locus-tag	class	description
AL497_RS00155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL497_RS00285	COG1802	Transcriptional regulator
AL497_RS00285	COG4626	Terminase
AL497_RS00300	COG0616	signal peptide processing
AL497_RS00435	COG3065	identical protein binding
AL497_RS00445	COG1199	ATP-dependent helicase activity
AL497_RS00450	COG0251	oxidation-reduction process
AL497_RS00470	COG1760	l-serine dehydratase
AL497_RS00475	COG2200	EAL domain
AL497_RS00480	COG1253	flavin adenine dinucleotide binding
AL497_RS00485	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS00485	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS00490	COG3715	PTS system
AL497_RS00495	COG3716	PTS system mannose fructose sorbose family IID component
AL497_RS00510	COG2226	methyltransferase
AL497_RS00515	COG0768	penicillin binding
AL497_RS00550	COG1414	Transcriptional regulator
AL497_RS00555	COG2814	Major facilitator Superfamily
AL497_RS00575	COG1956	GAF domain-containing protein
AL497_RS00580	COG2995	paraquat-inducible protein a
AL497_RS00585	COG3008	intermembrane lipid transfer
AL497_RS00610	COG2990	Protein conserved in bacteria
AL497_RS00650	COG1276	copper resistance
AL497_RS00655	COG2372	response to copper ion
AL497_RS00665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL497_RS00670	COG1770	oligopeptidase
AL497_RS00675	COG2979	Protein of unknown function (DUF533)
AL497_RS00680	COG3141	response to X-ray
AL497_RS00690	COG0800	Aldolase
AL497_RS00695	COG0129	dihydroxy-acid dehydratase activity
AL497_RS00700	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL497_RS00710	COG1737	Transcriptional regulator
AL497_RS00720	COG1560	Kdo2-lipid A biosynthetic process
AL497_RS00725	COG0739	heme binding
AL497_RS00730	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL497_RS00740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS00765	COG0494	nUDIX hydrolase
AL497_RS00775	COG1335	isochorismatase
AL497_RS00780	COG1801	Protein of unknown function DUF72
AL497_RS00785	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AL497_RS00805	COG3102	Protein conserved in bacteria
AL497_RS00815	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AL497_RS00845	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS00855	COG1879	ABC-type sugar transport system periplasmic component
AL497_RS00860	COG1528	Iron-storage protein
AL497_RS00885	COG1528	Iron-storage protein
AL497_RS00895	COG0814	amino acid
AL497_RS00900	COG3318	Belongs to the UPF0149 family
AL497_RS00900	COG3012	SEC-C Motif Domain Protein
AL497_RS00905	COG3152	Membrane
AL497_RS00910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL497_RS00940	COG2197	response regulator
AL497_RS00950	COG2197	response regulator
AL497_RS00955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL497_RS00960	COG1126	abc transporter atp-binding protein
AL497_RS00965	COG0765	amino acid transport
AL497_RS00975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS00980	COG0366	Alpha amylase catalytic
AL497_RS01010	COG5475	Uncharacterized small protein (DUF2158)
AL497_RS01015	COG2354	Protein conserved in bacteria
AL497_RS01020	COG0697	spore germination
AL497_RS01025	COG3727	T/G mismatch-specific endonuclease activity
AL497_RS01030	COG0270	DNA (cytosine-5-)-methyltransferase activity
AL497_RS01035	COG1418	mRNA catabolic process
AL497_RS01045	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL497_RS01065	COG1376	ErfK ybiS ycfS ynhG family protein
AL497_RS01085	COG2977	Belongs to the P-Pant transferase superfamily
AL497_RS01105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL497_RS01120	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL497_RS01140	COG1725	Transcriptional regulator
AL497_RS01150	COG0534	Mate efflux family protein
AL497_RS01165	COG0582	viral genome integration into host DNA
AL497_RS01175	COG1121	(ABC) transporter
AL497_RS01180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS01185	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL497_RS01215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL497_RS01225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL497_RS01230	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL497_RS01235	COG1121	(ABC) transporter
AL497_RS01240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS01245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS01275	COG0523	cobalamin synthesis protein
AL497_RS01305	COG0523	cobalamin synthesis protein
AL497_RS01315	COG0735	belongs to the Fur family
AL497_RS01320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS01340	COG0582	viral genome integration into host DNA
AL497_RS01345	COG1169	isochorismate synthase
AL497_RS01350	COG2814	Major facilitator Superfamily
AL497_RS01355	COG1132	(ABC) transporter
AL497_RS01370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL497_RS01370	COG3433	isochorismatase activity
AL497_RS01370	COG2226	methyltransferase
AL497_RS01390	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL497_RS01395	COG4771	TonB-dependent receptor
AL497_RS01470	COG3504	Conjugal transfer protein
AL497_RS01535	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AL497_RS01560	COG0154	amidase activity
AL497_RS01590	COG1960	acyl-CoA dehydrogenase activity
AL497_RS01595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL497_RS01600	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL497_RS01620	COG2197	response regulator
AL497_RS01665	COG3615	Tellurite resistance protein tehB
AL497_RS01670	COG5001	Diguanylate cyclase
AL497_RS01670	COG3300	MHYT domain
AL497_RS01680	COG0477	Major facilitator Superfamily
AL497_RS01685	COG0095	Lipoate-protein ligase
AL497_RS01695	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL497_RS01720	COG1289	transmembrane transporter activity
AL497_RS01730	COG1686	Belongs to the peptidase S11 family
AL497_RS01735	COG2925	Exonuclease
AL497_RS01740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL497_RS01745	COG0640	Transcriptional regulator
AL497_RS01750	COG0531	amino acid
AL497_RS01760	COG0583	DNA-binding transcription factor activity
AL497_RS01765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL497_RS01780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL497_RS01795	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL497_RS01820	COG0438	transferase activity, transferring glycosyl groups
AL497_RS01830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL497_RS01875	COG0438	transferase activity, transferring glycosyl groups
AL497_RS01910	COG2244	polysaccharide biosynthetic process
AL497_RS01915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL497_RS01955	COG1253	flavin adenine dinucleotide binding
AL497_RS01960	COG2982	Protein involved in outer membrane biogenesis
AL497_RS01975	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL497_RS01980	COG0443	Heat shock 70 kDa protein
AL497_RS02010	COG2205	protein histidine kinase activity
AL497_RS02015	COG0745	RESPONSE REGULATOR receiver
AL497_RS02020	COG0826	peptidase U32
AL497_RS02035	COG1070	Carbohydrate kinase
AL497_RS02045	COG2390	Transcriptional regulator
AL497_RS02070	COG1830	Aldolase
AL497_RS02075	COG0351	phosphomethylpyrimidine kinase
AL497_RS02100	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL497_RS02110	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL497_RS02120	COG0583	DNA-binding transcription factor activity
AL497_RS02130	COG2252	PERMEase
AL497_RS02135	COG0583	DNA-binding transcription factor activity
AL497_RS02140	COG5455	response to cobalt ion
AL497_RS02150	COG0489	protein tyrosine kinase activity
AL497_RS02165	COG4808	Protein conserved in bacteria
AL497_RS02170	COG4807	Protein conserved in bacteria
AL497_RS02180	COG3275	phosphorelay sensor kinase activity
AL497_RS02185	COG0789	Transcriptional regulator
AL497_RS02195	COG1174	glycine betaine transport
AL497_RS02200	COG1125	glycine betaine transport
AL497_RS02205	COG1174	glycine betaine transport
AL497_RS02210	COG1732	Glycine betaine
AL497_RS02215	COG1472	Belongs to the glycosyl hydrolase 3 family
AL497_RS02220	COG0277	FAD linked oxidase domain protein
AL497_RS02230	COG1686	Belongs to the peptidase S11 family
AL497_RS02240	COG0586	Pfam SNARE associated Golgi protein
AL497_RS02245	COG1538	Outer membrane efflux protein
AL497_RS02255	COG2723	6-phospho-beta-galactosidase activity
AL497_RS02270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL497_RS02275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL497_RS02280	COG0625	glutathione transferase activity
AL497_RS02295	COG2271	Major facilitator Superfamily
AL497_RS02300	COG0583	DNA-binding transcription factor activity
AL497_RS02310	COG1346	cytolysis
AL497_RS02320	COG2949	membrane
AL497_RS02330	COG1129	ABC transporter
AL497_RS02350	COG2311	Membrane
AL497_RS02380	COG1393	Belongs to the ArsC family
AL497_RS02385	COG4771	TonB-dependent receptor
AL497_RS02390	COG0833	amino acid
AL497_RS02405	COG0583	DNA-binding transcription factor activity
AL497_RS02410	COG2855	membrane
AL497_RS02420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS02420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS02420	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL497_RS02425	COG1105	Belongs to the carbohydrate kinase PfkB family
AL497_RS02455	COG1312	Catalyzes the dehydration of D-mannonate
AL497_RS02460	COG0246	Mannitol dehydrogenase
AL497_RS02465	COG0523	cobalamin synthesis protein
AL497_RS02470	COG0671	phosphoesterase, PA-phosphatase related
AL497_RS02475	COG0791	NLP P60 protein
AL497_RS02480	COG2200	EAL domain
AL497_RS02485	COG4166	transmembrane transport
AL497_RS02490	COG4174	ABC transporter (Permease)
AL497_RS02495	COG4239	(ABC) transporter, permease
AL497_RS02500	COG4172	Belongs to the ABC transporter superfamily
AL497_RS02515	COG2814	Major facilitator Superfamily
AL497_RS02520	COG1187	pseudouridine synthase activity
AL497_RS02525	COG1061	Type III restriction enzyme res subunit
AL497_RS02545	COG0494	nUDIX hydrolase
AL497_RS02550	COG1349	DNA-binding transcription factor activity
AL497_RS02575	COG0628	permease
AL497_RS02590	COG0659	secondary active sulfate transmembrane transporter activity
AL497_RS02595	COG2239	Acts as a magnesium transporter
AL497_RS02600	COG4615	Cyclic peptide transporter
AL497_RS02610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL497_RS02610	COG2169	Transcriptional regulator
AL497_RS02630	COG0642	Histidine kinase
AL497_RS02630	COG2198	Histidine kinase
AL497_RS02670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL497_RS02675	COG0584	glycerophosphoryl diester phosphodiesterase
AL497_RS02680	COG2271	Major facilitator Superfamily
AL497_RS02685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL497_RS02695	COG0247	lactate metabolic process
AL497_RS02720	COG0642	Histidine kinase
AL497_RS02745	COG0318	PFAM AMP-dependent synthetase and ligase
AL497_RS02770	COG1169	isochorismate synthase
AL497_RS02775	COG2153	protein acetylation
AL497_RS02790	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL497_RS02795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL497_RS02805	COG0839	Belongs to the complex I subunit 6 family
AL497_RS02860	COG0583	DNA-binding transcription factor activity
AL497_RS02865	COG0436	Aminotransferase
AL497_RS02875	COG0471	metal ion transport
AL497_RS02875	COG0490	domain, Protein
AL497_RS02880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL497_RS02910	COG0622	Phosphoesterase
AL497_RS02915	COG0625	glutathione transferase activity
AL497_RS02920	COG0625	glutathione transferase activity
AL497_RS02925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL497_RS02930	COG1090	epimerase
AL497_RS02950	COG4598	ABC transporter
AL497_RS02955	COG4160	amino acid transport
AL497_RS02970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS02980	COG0163	prenyltransferase activity
AL497_RS02985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL497_RS02990	COG1286	toxin biosynthetic process
AL497_RS02995	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL497_RS03000	COG0285	dihydrofolate synthase activity
AL497_RS03010	COG0586	Pfam SNARE associated Golgi protein
AL497_RS03020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL497_RS03035	COG2814	Major facilitator Superfamily
AL497_RS03040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL497_RS03055	COG3101	peptidyl-lysine hydroxylation
AL497_RS03060	COG0730	response to heat
AL497_RS03085	COG2062	phosphohistidine phosphatase, SixA
AL497_RS03100	COG3691	Protein conserved in bacteria
AL497_RS03110	COG2853	Lipoprotein
AL497_RS03115	COG2116	formate transmembrane transporter activity
AL497_RS03140	COG0590	tRNA wobble adenosine to inosine editing
AL497_RS03145	COG2807	transmembrane transport
AL497_RS03155	COG0436	Aminotransferase
AL497_RS03160	COG3275	phosphorelay sensor kinase activity
AL497_RS03165	COG3279	Response regulator of the LytR AlgR family
AL497_RS03180	COG3961	Belongs to the TPP enzyme family
AL497_RS03185	COG0667	Aldo Keto reductase
AL497_RS03200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL497_RS03205	COG2199	diguanylate cyclase activity
AL497_RS03205	COG2200	EAL domain
AL497_RS03220	COG3415	Transposase
AL497_RS03225	COG3415	Transposase
AL497_RS03265	COG0583	DNA-binding transcription factor activity
AL497_RS03270	COG0385	Bile acid
AL497_RS03275	COG3530	Putative quorum-sensing-regulated virulence factor
AL497_RS03300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS03340	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AL497_RS03345	COG4208	sulfate ABC transporter
AL497_RS03350	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL497_RS03355	COG4150	thiosulfate binding
AL497_RS03360	COG2837	iron assimilation
AL497_RS03380	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL497_RS03400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL497_RS03405	COG5342	invasion associated locus B
AL497_RS03415	COG0493	'glutamate synthase
AL497_RS03415	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS03420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL497_RS03430	COG1393	Belongs to the ArsC family
AL497_RS03445	COG0400	carboxylic ester hydrolase activity
AL497_RS03455	COG2321	neutral zinc metallopeptidase
AL497_RS03465	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL497_RS03475	COG2716	regulation of RNA biosynthetic process
AL497_RS03480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL497_RS03485	COG0628	permease
AL497_RS03490	COG4783	chaperone-mediated protein folding
AL497_RS03495	COG1393	Belongs to the ArsC family
AL497_RS03510	COG2233	PERMEase
AL497_RS03520	COG2723	6-phospho-beta-galactosidase activity
AL497_RS03535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL497_RS03545	COG2211	Major facilitator Superfamily
AL497_RS03550	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AL497_RS03565	COG0248	Ppx GppA phosphatase
AL497_RS03570	COG2200	EAL domain
AL497_RS03605	COG0516	GMP reductase activity
AL497_RS03605	COG0517	IMP dehydrogenase activity
AL497_RS03625	COG1645	bacterial-type flagellum-dependent swarming motility
AL497_RS03640	COG2976	Protein conserved in bacteria
AL497_RS03670	COG4953	penicillin-binding protein 1C
AL497_RS03675	COG2373	Large extracellular alpha-helical protein
AL497_RS03680	COG2897	thiosulfate sulfurtransferase activity
AL497_RS03695	COG2975	iron-sulfur cluster assembly
AL497_RS03700	COG0633	Ferredoxin
AL497_RS03720	COG0822	iron-sulfur transferase activity
AL497_RS03745	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AL497_RS03750	COG3683	transport system, periplasmic component
AL497_RS03755	COG3711	transcriptional antiterminator
AL497_RS03760	COG2814	Major facilitator Superfamily
AL497_RS03765	COG2259	Doxx family
AL497_RS03775	COG1017	nitric oxide dioxygenase activity
AL497_RS03775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL497_RS03780	COG0347	Belongs to the P(II) protein family
AL497_RS03785	COG2204	response regulator
AL497_RS03790	COG3170	Tfp pilus assembly protein FimV
AL497_RS03795	COG2205	protein histidine kinase activity
AL497_RS03800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL497_RS03800	COG0047	phosphoribosylformylglycinamidine synthase activity
AL497_RS03820	COG0560	Phosphoserine phosphatase
AL497_RS03830	COG1737	Transcriptional regulator
AL497_RS03835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS03845	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL497_RS03865	COG0681	Belongs to the peptidase S26 family
AL497_RS03875	COG3086	response to oxidative stress
AL497_RS03880	COG3026	antisigma factor binding
AL497_RS03885	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AL497_RS03895	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL497_RS03905	COG0513	Belongs to the DEAD box helicase family
AL497_RS03920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL497_RS03925	COG3118	belongs to the thioredoxin family
AL497_RS03930	COG3148	PFAM DTW domain containing protein
AL497_RS03940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL497_RS03945	COG5544	Lipoprotein
AL497_RS03950	COG0477	Major facilitator Superfamily
AL497_RS03985	COG0542	response to heat
AL497_RS04000	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL497_RS04005	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL497_RS04015	COG1605	Chorismate mutase
AL497_RS04015	COG0077	Prephenate dehydratase
AL497_RS04025	COG1605	Chorismate mutase
AL497_RS04025	COG0287	Prephenate dehydrogenase
AL497_RS04030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL497_RS04040	COG2199	diguanylate cyclase activity
AL497_RS04045	COG2885	chlorophyll binding
AL497_RS04080	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL497_RS04085	COG4137	Cytochrome C assembly protein
AL497_RS04090	COG4536	flavin adenine dinucleotide binding
AL497_RS04105	COG0497	DNA recombination
AL497_RS04120	COG2867	negative regulation of translational initiation
AL497_RS04235	COG0740	serine-type endopeptidase activity
AL497_RS04275	COG3772	lysozyme
AL497_RS04365	COG0582	viral genome integration into host DNA
AL497_RS04380	COG0582	viral genome integration into host DNA
AL497_RS04430	COG0210	DNA helicase
AL497_RS04435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL497_RS04460	COG4983	Phage plasmid primase, P4 family domain protein
AL497_RS04465	COG3596	GTP binding
AL497_RS04510	COG2003	Belongs to the UPF0758 family
AL497_RS04540	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL497_RS04550	COG2169	Transcriptional regulator
AL497_RS04555	COG3813	Protein conserved in bacteria
AL497_RS04560	COG0243	molybdopterin cofactor binding
AL497_RS04565	COG3005	denitrification pathway
AL497_RS04570	COG4235	cytochrome complex assembly
AL497_RS04570	COG3088	subunit of a heme lyase
AL497_RS04575	COG3088	subunit of a heme lyase
AL497_RS04575	COG4235	cytochrome complex assembly
AL497_RS04580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL497_RS04585	COG1138	Cytochrome C-type biogenesis protein
AL497_RS04595	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL497_RS04600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL497_RS04605	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL497_RS04610	COG4133	protoheme IX ABC transporter activity
AL497_RS04615	COG0477	Major facilitator Superfamily
AL497_RS04620	COG0583	DNA-binding transcription factor activity
AL497_RS04625	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL497_RS04630	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS04660	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AL497_RS04665	COG0747	negative chemotaxis
AL497_RS04670	COG0601	transmembrane transport
AL497_RS04675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL497_RS04680	COG0444	Belongs to the ABC transporter superfamily
AL497_RS04685	COG4608	Belongs to the ABC transporter superfamily
AL497_RS04700	COG3284	Transcriptional regulator
AL497_RS04705	COG0671	phosphoesterase, PA-phosphatase related
AL497_RS04710	COG0583	DNA-binding transcription factor activity
AL497_RS04720	COG0640	Transcriptional regulator
AL497_RS04725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL497_RS04755	COG4575	ribosome binding
AL497_RS04765	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL497_RS04770	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL497_RS04780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL497_RS04785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL497_RS04795	COG4176	ABC-type proline glycine betaine transport system permease component
AL497_RS04805	COG1846	Transcriptional regulator
AL497_RS04810	COG1566	PFAM secretion protein HlyD family protein
AL497_RS04815	COG2814	Major facilitator Superfamily
AL497_RS04820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL497_RS04840	COG1238	metal cluster binding
AL497_RS04845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL497_RS04850	COG2823	Periplasmic or secreted lipoprotein
AL497_RS04880	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AL497_RS04905	COG1546	Belongs to the CinA family
AL497_RS04910	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL497_RS04915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS04930	COG2951	lytic endotransglycosylase activity
AL497_RS04935	COG3730	PTS system glucitol sorbitol-specific
AL497_RS04940	COG3732	PTS system glucitol sorbitol-specific
AL497_RS04950	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS04955	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS04960	COG1349	DNA-binding transcription factor activity
AL497_RS04990	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AL497_RS04995	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AL497_RS05000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS05005	COG1609	Transcriptional regulator
AL497_RS05010	COG1263	PTS System
AL497_RS05010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS05015	COG2723	6-phospho-beta-galactosidase activity
AL497_RS05025	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AL497_RS05035	COG3260	NADH ubiquinone oxidoreductase 20
AL497_RS05040	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL497_RS05045	COG3261	NADH dehydrogenase
AL497_RS05045	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AL497_RS05050	COG0650	Formate hydrogenlyase subunit 4
AL497_RS05055	COG0651	ATP synthesis coupled electron transport
AL497_RS05060	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS05075	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AL497_RS05080	COG0298	carbon dioxide binding
AL497_RS05085	COG0409	Hydrogenase expression formation protein
AL497_RS05090	COG0309	Hydrogenase expression formation protein (HypE)
AL497_RS05105	COG1121	(ABC) transporter
AL497_RS05110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS05115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL497_RS05130	COG0583	DNA-binding transcription factor activity
AL497_RS05135	COG0679	Auxin Efflux Carrier
AL497_RS05155	COG3720	iron ion transport
AL497_RS05160	COG4558	Periplasmic binding protein
AL497_RS05165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS05200	COG3121	Chaperone
AL497_RS05215	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL497_RS05220	COG0163	prenyltransferase activity
AL497_RS05240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL497_RS05245	COG4942	peptidase
AL497_RS05245	COG1388	LysM domain
AL497_RS05275	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AL497_RS05305	COG2234	aminopeptidase activity
AL497_RS05330	COG0720	synthase
AL497_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS05340	COG0602	queuosine metabolic process
AL497_RS05360	COG3956	TIGRFAM MazG family protein
AL497_RS05365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL497_RS05375	COG3437	response regulator, receiver
AL497_RS05375	COG3850	Histidine kinase
AL497_RS05375	COG2205	protein histidine kinase activity
AL497_RS05375	COG4999	Histidine kinase
AL497_RS05380	COG1929	Belongs to the glycerate kinase type-1 family
AL497_RS05385	COG4948	Mandelate Racemase Muconate Lactonizing
AL497_RS05390	COG4948	Mandelate Racemase Muconate Lactonizing
AL497_RS05395	COG2271	Major facilitator Superfamily
AL497_RS05405	COG0716	FMN binding
AL497_RS05410	COG0564	pseudouridine synthase activity
AL497_RS05415	COG3098	single-species biofilm formation
AL497_RS05430	COG1611	Belongs to the LOG family
AL497_RS05435	COG0814	amino acid
AL497_RS05440	COG1760	l-serine dehydratase
AL497_RS05455	COG2363	Small membrane protein
AL497_RS05460	COG0583	DNA-binding transcription factor activity
AL497_RS05465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL497_RS05470	COG2166	iron-sulfur cluster assembly
AL497_RS05475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL497_RS05480	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL497_RS05500	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL497_RS05505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL497_RS05505	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL497_RS05510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL497_RS05515	COG1074	ATP-dependent DNA helicase activity
AL497_RS05520	COG1025	Belongs to the peptidase M16 family
AL497_RS05525	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL497_RS05540	COG4795	General secretion pathway protein
AL497_RS05545	COG2165	general secretion pathway protein
AL497_RS05585	COG0861	Integral membrane protein TerC family
AL497_RS05595	COG0667	Aldo Keto reductase
AL497_RS05620	COG1609	Transcriptional regulator
AL497_RS05630	COG1609	Transcriptional regulator
AL497_RS05640	COG0583	DNA-binding transcription factor activity
AL497_RS05645	COG1794	racemase activity, acting on amino acids and derivatives
AL497_RS05670	COG2814	Major facilitator Superfamily
AL497_RS05675	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS05680	COG0183	Belongs to the thiolase family
AL497_RS05685	COG0583	DNA-binding transcription factor activity
AL497_RS05695	COG0814	amino acid
AL497_RS05700	COG0667	Aldo Keto reductase
AL497_RS05715	COG0640	Transcriptional regulator
AL497_RS05730	COG0697	spore germination
AL497_RS05735	COG1846	Transcriptional regulator
AL497_RS05745	COG0154	amidase activity
AL497_RS05750	COG1960	acyl-CoA dehydrogenase activity
AL497_RS05760	COG4638	Rieske (2fe-2S)
AL497_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS05780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL497_RS05795	COG3188	usher protein
AL497_RS05800	COG3121	Chaperone
AL497_RS05805	COG3539	Fimbrial protein
AL497_RS05830	COG0582	viral genome integration into host DNA
AL497_RS05835	COG4974	Belongs to the 'phage' integrase family
AL497_RS05850	COG3539	Fimbrial protein
AL497_RS05855	COG3121	Chaperone
AL497_RS05860	COG3188	usher protein
AL497_RS05865	COG3539	Fimbrial protein
AL497_RS05870	COG3539	Fimbrial protein
AL497_RS05875	COG3539	Fimbrial protein
AL497_RS05885	COG2388	GCN5-related N-acetyl-transferase
AL497_RS05890	COG3592	Divergent 4Fe-4S mono-cluster
AL497_RS05910	COG1289	transmembrane transporter activity
AL497_RS05915	COG1538	Outer membrane efflux protein
AL497_RS05925	COG1982	Orn Lys Arg decarboxylase major
AL497_RS05930	COG0531	amino acid
AL497_RS05945	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL497_RS05970	COG2271	Major facilitator Superfamily
AL497_RS05975	COG0483	inositol monophosphate 1-phosphatase activity
AL497_RS05980	COG1609	Transcriptional regulator
AL497_RS05985	COG0753	catalase activity
AL497_RS05995	COG0531	amino acid
AL497_RS06005	COG0124	histidyl-tRNA synthetase
AL497_RS06010	COG0124	histidyl-tRNA synthetase
AL497_RS06025	COG3539	Fimbrial protein
AL497_RS06035	COG3121	Chaperone
AL497_RS06040	COG3188	usher protein
AL497_RS06050	COG3539	Fimbrial protein
AL497_RS06080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL497_RS06090	COG4942	peptidase
AL497_RS06095	COG0583	DNA-binding transcription factor activity
AL497_RS06100	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL497_RS06110	COG1811	Na channel or pump
AL497_RS06130	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL497_RS06140	COG4974	Belongs to the 'phage' integrase family
AL497_RS06145	COG0716	FMN binding
AL497_RS06155	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL497_RS06165	COG1272	protein, Hemolysin III
AL497_RS06175	COG1737	Transcriptional regulator
AL497_RS06180	COG2723	6-phospho-beta-galactosidase activity
AL497_RS06200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL497_RS06205	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS06225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL497_RS06230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL497_RS06235	COG0006	proline dipeptidase activity
AL497_RS06255	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL497_RS06260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL497_RS06275	COG2968	Membrane
AL497_RS06280	COG1279	arginine transmembrane transporter activity
AL497_RS06285	COG0668	transmembrane transport
AL497_RS06290	COG0583	DNA-binding transcription factor activity
AL497_RS06300	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL497_RS06305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL497_RS06310	COG2271	Major facilitator Superfamily
AL497_RS06315	COG0549	Belongs to the carbamate kinase family
AL497_RS06320	COG0191	fructose-bisphosphate aldolase activity
AL497_RS06335	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL497_RS06340	COG0501	Belongs to the peptidase M48B family
AL497_RS06360	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AL497_RS06365	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS06395	COG1414	Transcriptional regulator
AL497_RS06400	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS06415	COG2146	nitrite reductase [NAD(P)H] activity
AL497_RS06455	COG2814	Major facilitator Superfamily
AL497_RS06465	COG2356	endonuclease I
AL497_RS06470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL497_RS06475	COG0189	ligase activity
AL497_RS06495	COG2197	response regulator
AL497_RS06500	COG2805	Type II/IV secretion system protein
AL497_RS06505	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL497_RS06510	COG0762	integral membrane protein
AL497_RS06525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL497_RS06540	COG4214	carbohydrate transport
AL497_RS06550	COG3171	Protein conserved in bacteria
AL497_RS06560	COG1194	a g-specific adenine glycosylase
AL497_RS06575	COG2211	Major facilitator Superfamily
AL497_RS06580	COG1982	Orn Lys Arg decarboxylase major
AL497_RS06590	COG1811	Na channel or pump
AL497_RS06615	COG2731	YhcH YjgK YiaL family protein
AL497_RS06640	COG2186	Transcriptional regulator
AL497_RS06660	COG2382	esterase
AL497_RS06670	COG4771	TonB-dependent receptor
AL497_RS06680	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AL497_RS06695	COG1917	Cupin 2, conserved barrel domain protein
AL497_RS06695	COG4977	sequence-specific DNA binding
AL497_RS06700	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL497_RS06705	COG3753	Protein conserved in bacteria
AL497_RS06710	COG1652	LysM domain
AL497_RS06715	COG0583	DNA-binding transcription factor activity
AL497_RS06725	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL497_RS06730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL497_RS06745	COG2072	flavoprotein involved in K transport
AL497_RS06755	COG0583	DNA-binding transcription factor activity
AL497_RS06765	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS06785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL497_RS06790	COG0754	glutathionylspermidine amidase activity
AL497_RS06800	COG0625	glutathione transferase activity
AL497_RS06810	COG0848	biopolymer transport protein
AL497_RS06825	COG0626	cystathionine gamma-synthase activity
AL497_RS06830	COG0586	Pfam SNARE associated Golgi protein
AL497_RS06835	COG2207	Transcriptional regulator
AL497_RS06845	COG1979	alcohol dehydrogenase
AL497_RS06850	COG0656	L-ascorbic acid biosynthetic process
AL497_RS06860	COG1032	radical SAM domain protein
AL497_RS06870	COG0204	Acyl-transferase
AL497_RS06885	COG3111	PFAM Bacterial OB fold (BOF) protein
AL497_RS06895	COG0642	Histidine kinase
AL497_RS06900	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL497_RS06905	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL497_RS06910	COG0187	DNA topoisomerase II activity
AL497_RS06915	COG3150	esterase
AL497_RS06920	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL497_RS06925	COG3151	Protein conserved in bacteria
AL497_RS06930	COG0494	nUDIX hydrolase
AL497_RS06945	COG0754	glutathionylspermidine amidase activity
AL497_RS06950	COG3384	dioxygenase
AL497_RS06960	COG2960	long-chain fatty acid transporting porin activity
AL497_RS06980	COG3025	triphosphatase activity
AL497_RS06985	COG4991	sh3 domain protein
AL497_RS07000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL497_RS07010	COG0477	Major facilitator Superfamily
AL497_RS07020	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL497_RS07025	COG0358	DNA primase activity
AL497_RS07035	COG3663	DNA glycosylase
AL497_RS07075	COG3119	arylsulfatase activity
AL497_RS07080	COG0641	radical SAM
AL497_RS07085	COG0714	Associated with various cellular activities
AL497_RS07120	COG0641	radical SAM
AL497_RS07145	COG2376	Dihydroxyacetone kinase
AL497_RS07150	COG1461	Dihydroxyacetone kinase
AL497_RS07165	COG2375	cellular response to nickel ion
AL497_RS07170	COG1695	Transcriptional regulator
AL497_RS07180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL497_RS07185	COG1609	Transcriptional regulator
AL497_RS07190	COG3250	beta-galactosidase activity
AL497_RS07195	COG2731	YhcH YjgK YiaL family protein
AL497_RS07200	COG0531	amino acid
AL497_RS07205	COG0531	amino acid
AL497_RS07215	COG3408	Glycogen debranching enzyme
AL497_RS07215	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AL497_RS07260	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL497_RS07260	COG1902	pentaerythritol trinitrate reductase activity
AL497_RS07270	COG1451	nucleotide metabolic process
AL497_RS07275	COG0673	inositol 2-dehydrogenase activity
AL497_RS07280	COG0861	Integral membrane protein TerC family
AL497_RS07295	COG2721	sulfolactate sulfo-lyase activity
AL497_RS07305	COG2271	Major facilitator Superfamily
AL497_RS07310	COG2186	Transcriptional regulator
AL497_RS07315	COG0586	Pfam SNARE associated Golgi protein
AL497_RS07325	COG1422	Protein of unknown function (DUF1090)
AL497_RS07330	COG4575	ribosome binding
AL497_RS07335	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AL497_RS07350	COG2259	Doxx family
AL497_RS07355	COG0435	Glutathione S-transferase
AL497_RS07360	COG3152	Membrane
AL497_RS07365	COG0583	DNA-binding transcription factor activity
AL497_RS07370	COG1741	Belongs to the pirin family
AL497_RS07385	COG0668	transmembrane transport
AL497_RS07405	COG1929	Belongs to the glycerate kinase type-1 family
AL497_RS07410	COG2084	Dehydrogenase
AL497_RS07420	COG2721	sulfolactate sulfo-lyase activity
AL497_RS07425	COG1349	DNA-binding transcription factor activity
AL497_RS07435	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS07445	COG3716	PTS system mannose fructose sorbose family IID component
AL497_RS07450	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS07455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL497_RS07460	COG2222	sugar isomerase
AL497_RS07475	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL497_RS07495	COG2823	Periplasmic or secreted lipoprotein
AL497_RS07505	COG0701	Predicted permease
AL497_RS07510	COG0702	epimerase
AL497_RS07515	COG0693	protein deglycase activity
AL497_RS07530	COG3153	acetyltransferase
AL497_RS07535	COG3154	lipid carrier protein
AL497_RS07540	COG0826	peptidase U32
AL497_RS07545	COG0826	peptidase U32
AL497_RS07550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS07555	COG0814	amino acid
AL497_RS07605	COG0195	Participates in both transcription termination and antitermination
AL497_RS07645	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL497_RS07655	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL497_RS07660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL497_RS07670	COG1534	Rna-binding protein
AL497_RS07680	COG2027	D-alanyl-D-alanine carboxypeptidase
AL497_RS07690	COG0697	spore germination
AL497_RS07705	COG0142	geranyltranstransferase activity
AL497_RS07710	COG3423	Transcriptional regulator
AL497_RS07720	COG5007	Belongs to the BolA IbaG family
AL497_RS07725	COG3113	response to antibiotic
AL497_RS07730	COG2854	intermembrane phospholipid transfer
AL497_RS07735	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL497_RS07740	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL497_RS07745	COG1127	ABC transporter
AL497_RS07755	COG0530	calcium, potassium:sodium antiporter activity
AL497_RS07765	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AL497_RS07770	COG3117	lipopolysaccharide transmembrane transporter activity
AL497_RS07775	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL497_RS07780	COG1137	ATPase activity
AL497_RS07785	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL497_RS07790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL497_RS07795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS07805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS07810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL497_RS07815	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL497_RS07820	COG2198	Histidine kinase
AL497_RS07820	COG0784	Response regulator, receiver
AL497_RS07820	COG5002	protein histidine kinase activity
AL497_RS07835	COG0069	glutamate synthase activity
AL497_RS07835	COG0070	glutamate synthase
AL497_RS07835	COG0067	glutamate synthase
AL497_RS07840	COG0493	'glutamate synthase
AL497_RS07845	COG2969	positive regulation of protein catabolic process
AL497_RS07850	COG0625	glutathione transferase activity
AL497_RS07870	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL497_RS07875	COG3105	Protein conserved in bacteria
AL497_RS07880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL497_RS07885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL497_RS07920	COG2732	(Barnase) inhibitor
AL497_RS07925	COG1289	transmembrane transporter activity
AL497_RS07940	COG0583	DNA-binding transcription factor activity
AL497_RS07945	COG0312	modulator of DNA gyrase
AL497_RS07950	COG3164	Protein of unknown function
AL497_RS07965	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL497_RS07970	COG1792	Involved in formation and maintenance of cell shape
AL497_RS07975	COG1077	Cell shape determining protein MreB Mrl
AL497_RS07985	COG2200	EAL domain
AL497_RS07985	COG2199	diguanylate cyclase activity
AL497_RS07990	COG0604	alcohol dehydrogenase
AL497_RS08005	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL497_RS08015	COG0511	ligase activity, forming carbon-carbon bonds
AL497_RS08020	COG0439	Biotin carboxylase
AL497_RS08025	COG3924	membrane
AL497_RS08030	COG4145	pantothenate transmembrane transporter activity
AL497_RS08050	COG1309	transcriptional regulator
AL497_RS08055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS08060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL497_RS08100	COG2850	peptidyl-arginine hydroxylation
AL497_RS08105	COG5002	protein histidine kinase activity
AL497_RS08110	COG0745	RESPONSE REGULATOR receiver
AL497_RS08120	COG1538	Outer membrane efflux protein
AL497_RS08125	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS08130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS08135	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL497_RS08240	COG0582	viral genome integration into host DNA
AL497_RS08250	COG0288	reversible hydration of carbon dioxide
AL497_RS08255	COG0659	secondary active sulfate transmembrane transporter activity
AL497_RS08260	COG1064	alcohol dehydrogenase
AL497_RS08265	COG1175	transmembrane transport
AL497_RS08270	COG0395	ABC-type sugar transport system, permease component
AL497_RS08275	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL497_RS08280	COG3842	ATPase activity
AL497_RS08290	COG2814	Major facilitator Superfamily
AL497_RS08300	COG1082	Xylose isomerase domain protein TIM barrel
AL497_RS08310	COG3962	Belongs to the TPP enzyme family
AL497_RS08315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL497_RS08320	COG1737	Transcriptional regulator
AL497_RS08320	COG0837	glucose binding
AL497_RS08325	COG3718	enzyme involved in inositol metabolism
AL497_RS08340	COG0433	COG0433 Predicted ATPase
AL497_RS08350	COG0795	lipopolysaccharide-transporting ATPase activity
AL497_RS08355	COG0795	lipopolysaccharide-transporting ATPase activity
AL497_RS08370	COG2927	DNA polymerase III (CHI subunit)
AL497_RS08375	COG0525	valine-tRNA ligase activity
AL497_RS08395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL497_RS08400	COG2731	YhcH YjgK YiaL family protein
AL497_RS08420	COG0251	oxidation-reduction process
AL497_RS08425	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AL497_RS08445	COG1263	PTS System
AL497_RS08445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS08450	COG0366	Alpha amylase catalytic
AL497_RS08455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS08460	COG1486	melibiose metabolic process
AL497_RS08485	COG0602	queuosine metabolic process
AL497_RS08490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS08490	COG3711	transcriptional antiterminator
AL497_RS08495	COG2706	6-phosphogluconolactonase activity
AL497_RS08510	COG3964	amidohydrolase
AL497_RS08545	COG0312	modulator of DNA gyrase
AL497_RS08560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL497_RS08570	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS08575	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS08580	COG1129	ABC transporter
AL497_RS08585	COG1879	ABC-type sugar transport system periplasmic component
AL497_RS08595	COG2105	PFAM AIG2 family protein
AL497_RS08600	COG2911	Protein conserved in bacteria
AL497_RS08605	COG0729	surface antigen
AL497_RS08615	COG1253	flavin adenine dinucleotide binding
AL497_RS08625	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL497_RS08640	COG1733	regulation of RNA biosynthetic process
AL497_RS08645	COG0702	epimerase
AL497_RS08655	COG0697	spore germination
AL497_RS08665	COG1113	amino acid transport
AL497_RS08670	COG0545	Peptidyl-prolyl cis-trans isomerase
AL497_RS08675	COG3061	Opacity-associated protein A
AL497_RS08685	COG0359	binds to the 23S rRNA
AL497_RS08690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL497_RS08695	COG2965	DNA replication, synthesis of RNA primer
AL497_RS08755	COG1073	alpha beta
AL497_RS08760	COG3650	response to hydrogen peroxide
AL497_RS08770	COG1960	acyl-CoA dehydrogenase activity
AL497_RS08775	COG0477	Major facilitator Superfamily
AL497_RS08780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL497_RS08785	COG0557	exoribonuclease II activity
AL497_RS08800	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL497_RS08810	COG0330	HflC and HflK could
AL497_RS08815	COG0330	HflC and HflK could
AL497_RS08820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL497_RS08840	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL497_RS08845	COG0802	atpase or kinase
AL497_RS08850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL497_RS08850	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL497_RS08855	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL497_RS08875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS08900	COG3264	Mechanosensitive ion channel
AL497_RS08900	COG1511	domain protein
AL497_RS08915	COG1053	succinate dehydrogenase
AL497_RS08920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL497_RS08940	COG2076	Multidrug Resistance protein
AL497_RS08945	COG5510	response to toxic substance
AL497_RS08960	COG1509	lysine 2,3-aminomutase activity
AL497_RS09015	COG0459	protein refolding
AL497_RS09025	COG0531	amino acid
AL497_RS09030	COG3030	protein affecting phage T7 exclusion by the F plasmid
AL497_RS09040	COG1027	Aspartate ammonia-lyase
AL497_RS09045	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL497_RS09060	COG1309	transcriptional regulator
AL497_RS09090	COG0457	Tetratricopeptide repeat
AL497_RS09095	COG1649	PFAM Uncharacterised BCR, COG1649
AL497_RS09095	COG0726	polysaccharide deacetylase
AL497_RS09100	COG1215	transferase activity, transferring glycosyl groups
AL497_RS09115	COG0861	Integral membrane protein TerC family
AL497_RS09150	COG1486	melibiose metabolic process
AL497_RS09160	COG2169	Transcriptional regulator
AL497_RS09175	COG2824	Alkylphosphonate utilization operon protein PhnA
AL497_RS09180	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AL497_RS09185	COG2188	Transcriptional regulator
AL497_RS09190	COG3624	Phosphonate C-P lyase system protein PhnG
AL497_RS09195	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AL497_RS09200	COG3626	phosphonate metabolism
AL497_RS09205	COG3627	carbon phosphorus lyase activity
AL497_RS09210	COG4107	phosphonate C-P lyase system protein PhnK
AL497_RS09215	COG4778	phosphonate C-P lyase system protein PhnL
AL497_RS09220	COG3454	Phosphonate metabolism
AL497_RS09230	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AL497_RS09240	COG4191	Histidine kinase
AL497_RS09240	COG0784	Response regulator, receiver
AL497_RS09245	COG1129	ABC transporter
AL497_RS09250	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS09275	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AL497_RS09280	COG1301	dicarboxylic acid transport
AL497_RS09290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL497_RS09295	COG3162	membrane
AL497_RS09305	COG3539	Fimbrial protein
AL497_RS09310	COG3539	Fimbrial protein
AL497_RS09325	COG3539	Fimbrial protein
AL497_RS09330	COG1346	cytolysis
AL497_RS09340	COG0583	DNA-binding transcription factor activity
AL497_RS09345	COG0025	NhaP-type Na H and K H
AL497_RS09350	COG2252	PERMEase
AL497_RS09360	COG0625	glutathione transferase activity
AL497_RS09365	COG0789	Transcriptional regulator
AL497_RS09375	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL497_RS09390	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL497_RS09430	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL497_RS09445	COG2315	Protein conserved in bacteria
AL497_RS09450	COG0432	Pfam Uncharacterised protein family UPF0047
AL497_RS09460	COG1448	Aminotransferase
AL497_RS09465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL497_RS09470	COG0305	Participates in initiation and elongation during chromosome replication
AL497_RS09485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL497_RS09495	COG0735	belongs to the Fur family
AL497_RS09500	COG3237	CsbD-like
AL497_RS09505	COG0534	Mate efflux family protein
AL497_RS09515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL497_RS09540	COG4580	involved in the transport of maltose and maltodextrins
AL497_RS09595	COG0251	oxidation-reduction process
AL497_RS09600	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL497_RS09615	COG0527	aspartate kinase activity
AL497_RS09620	COG3541	Predicted nucleotidyltransferase
AL497_RS09625	COG1690	Belongs to the RtcB family
AL497_RS09635	COG4650	regulator
AL497_RS09660	COG1187	pseudouridine synthase activity
AL497_RS09675	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL497_RS09680	COG1410	methionine synthase
AL497_RS09680	COG0646	methionine synthase
AL497_RS09700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL497_RS09745	COG0151	Belongs to the GarS family
AL497_RS09755	COG4191	Histidine kinase
AL497_RS09795	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AL497_RS09810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL497_RS09815	COG2104	thiamine diphosphate biosynthetic process
AL497_RS09835	COG3706	GGDEF domain
AL497_RS09845	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL497_RS09850	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL497_RS09890	COG0250	Participates in transcription elongation, termination and antitermination
AL497_RS09995	COG0583	DNA-binding transcription factor activity
AL497_RS10020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL497_RS10035	COG3443	Belongs to the bacterial solute-binding protein 9 family
AL497_RS10040	COG2207	Transcriptional regulator
AL497_RS10050	COG0371	Dehydrogenase
AL497_RS10055	COG0697	spore germination
AL497_RS10065	COG0527	aspartate kinase activity
AL497_RS10065	COG0460	homoserine dehydrogenase
AL497_RS10070	COG0626	cystathionine gamma-synthase activity
AL497_RS10085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL497_RS10090	COG1609	Transcriptional regulator
AL497_RS10095	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL497_RS10110	COG1575	Belongs to the MenA family. Type 1 subfamily
AL497_RS10130	COG3678	ATP-independent chaperone mediated protein folding
AL497_RS10135	COG0745	RESPONSE REGULATOR receiver
AL497_RS10140	COG2205	protein histidine kinase activity
AL497_RS10145	COG2258	MOSC domain
AL497_RS10150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL497_RS10190	COG1454	alcohol dehydrogenase
AL497_RS10200	COG2271	Major facilitator Superfamily
AL497_RS10205	COG2731	YhcH YjgK YiaL family protein
AL497_RS10210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL497_RS10215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL497_RS10225	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AL497_RS10245	COG3383	formate dehydrogenase (NAD+) activity
AL497_RS10245	COG0243	molybdopterin cofactor binding
AL497_RS10250	COG3383	formate dehydrogenase (NAD+) activity
AL497_RS10250	COG0243	molybdopterin cofactor binding
AL497_RS10255	COG0437	4 iron, 4 sulfur cluster binding
AL497_RS10260	COG2864	formate dehydrogenase
AL497_RS10270	COG0657	acetylesterase activity
AL497_RS10275	COG0456	acetyltransferase
AL497_RS10290	COG1011	Hydrolase
AL497_RS10310	COG3852	Histidine kinase
AL497_RS10320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL497_RS10355	COG0204	Acyl-transferase
AL497_RS10365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL497_RS10370	COG3084	Protein conserved in bacteria
AL497_RS10380	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL497_RS10415	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AL497_RS10425	COG1739	Uncharacterized protein family UPF0029
AL497_RS10470	COG0805	protein transport
AL497_RS10480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL497_RS10490	COG3165	ubiquinone biosynthetic process from chorismate
AL497_RS10520	COG0583	DNA-binding transcription factor activity
AL497_RS10525	COG0697	spore germination
AL497_RS10530	COG0561	phosphatase activity
AL497_RS10535	COG2267	carboxylic ester hydrolase activity
AL497_RS10540	COG1280	lysine exporter protein (LysE YggA)
AL497_RS10550	COG1280	lysine exporter protein (LysE YggA)
AL497_RS10565	COG2050	protein possibly involved in aromatic compounds catabolism
AL497_RS10580	COG0210	DNA helicase
AL497_RS10585	COG1011	Hydrolase
AL497_RS10615	COG3072	Adenylate cyclase
AL497_RS10625	COG1587	Uroporphyrinogen-III synthase
AL497_RS10630	COG2959	enzyme of heme biosynthesis
AL497_RS10635	COG3071	HemY protein
AL497_RS10685	COG2244	polysaccharide biosynthetic process
AL497_RS10690	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL497_RS10695	COG0456	acetyltransferase
AL497_RS10700	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AL497_RS10705	COG1088	dTDP-glucose 4,6-dehydratase activity
AL497_RS10710	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL497_RS10715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL497_RS10725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL497_RS10730	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL497_RS10740	COG3118	belongs to the thioredoxin family
AL497_RS10755	COG0583	DNA-binding transcription factor activity
AL497_RS10765	COG1811	Na channel or pump
AL497_RS10775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL497_RS10780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL497_RS10795	COG0583	DNA-binding transcription factor activity
AL497_RS10800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL497_RS10810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL497_RS10815	COG3978	acetolactate synthase activity
AL497_RS10830	COG0606	chelatase, subunit chli
AL497_RS10835	COG3085	chromosome segregation
AL497_RS10885	COG2186	Transcriptional regulator
AL497_RS10890	COG0477	Major facilitator Superfamily
AL497_RS10895	COG1609	Transcriptional regulator
AL497_RS10900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL497_RS10910	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS10915	COG1129	ABC transporter
AL497_RS10945	COG1522	sequence-specific DNA binding
AL497_RS10950	COG0716	FMN binding
AL497_RS10965	COG3312	ion transport
AL497_RS11000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL497_RS11005	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL497_RS11015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL497_RS11020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL497_RS11025	COG0573	inorganic phosphate transmembrane transporter activity
AL497_RS11030	COG0581	inorganic phosphate transmembrane transporter activity
AL497_RS11040	COG0704	Plays a role in the regulation of phosphate uptake
AL497_RS11055	COG2382	esterase
AL497_RS11060	COG0363	glucosamine-6-phosphate deaminase activity
AL497_RS11065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL497_RS11075	COG2252	PERMEase
AL497_RS11080	COG0431	NADPH-dependent FMN reductase
AL497_RS11085	COG2091	lysine biosynthetic process via aminoadipic acid
AL497_RS11115	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL497_RS11125	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL497_RS11135	COG0592	DNA-directed DNA polymerase activity
AL497_RS11145	COG0187	DNA topoisomerase II activity
AL497_RS11150	COG0561	phosphatase activity
AL497_RS11165	COG2186	Transcriptional regulator
AL497_RS11170	COG3734	2-keto-3-deoxy-galactonokinase
AL497_RS11175	COG0800	Aldolase
AL497_RS11185	COG2271	Major facilitator Superfamily
AL497_RS11190	COG0823	Involved in the tonB-independent uptake of proteins
AL497_RS11195	COG5645	(Lipo)protein
AL497_RS11215	COG2188	Transcriptional regulator
AL497_RS11230	COG2149	membrane
AL497_RS11250	COG2610	gluconate transmembrane transporter activity
AL497_RS11255	COG0583	DNA-binding transcription factor activity
AL497_RS11260	COG2814	Major facilitator Superfamily
AL497_RS11290	COG0028	Belongs to the TPP enzyme family
AL497_RS11295	COG0440	acetolactate synthase activity
AL497_RS11300	COG2197	response regulator
AL497_RS11310	COG2271	Major facilitator Superfamily
AL497_RS11345	COG2188	Transcriptional regulator
AL497_RS11375	COG4580	involved in the transport of maltose and maltodextrins
AL497_RS11380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS11380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS11390	COG1609	Transcriptional regulator
AL497_RS11415	COG0697	spore germination
AL497_RS11465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL497_RS11480	COG1263	PTS System
AL497_RS11480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS11485	COG1464	Belongs to the NlpA lipoprotein family
AL497_RS11495	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AL497_RS11505	COG1064	alcohol dehydrogenase
AL497_RS11520	COG3311	Transcriptional regulator
AL497_RS11525	COG1569	PIN domain
AL497_RS11555	COG2211	Major facilitator Superfamily
AL497_RS11560	COG1501	Belongs to the glycosyl hydrolase 31 family
AL497_RS11565	COG3711	transcriptional antiterminator
AL497_RS11570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS11570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS11570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS11575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS11580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS11580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS11590	COG0191	fructose-bisphosphate aldolase activity
AL497_RS11595	COG1940	carbohydrate kinase activity
AL497_RS11615	COG1486	melibiose metabolic process
AL497_RS11620	COG1263	PTS System
AL497_RS11620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS11625	COG2982	Protein involved in outer membrane biogenesis
AL497_RS11630	COG2233	PERMEase
AL497_RS11635	COG0786	glutamate:sodium symporter activity
AL497_RS11650	COG3074	FtsZ-dependent cytokinesis
AL497_RS11655	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AL497_RS11680	COG3152	Membrane
AL497_RS11690	COG1494	fructose-1,6-bisphosphatase
AL497_RS11695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL497_RS11700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL497_RS11705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL497_RS11715	COG0194	GDP metabolic process
AL497_RS11725	COG2194	sulfuric ester hydrolase activity
AL497_RS11730	COG2860	membrane
AL497_RS11735	COG1561	YicC-like family, N-terminal region
AL497_RS11760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL497_RS11770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL497_RS11795	COG1519	Transferase
AL497_RS11810	COG1216	Glycosyl transferase, family 2
AL497_RS11825	COG0438	transferase activity, transferring glycosyl groups
AL497_RS11830	COG0859	PFAM glycosyl transferase family 9
AL497_RS11835	COG0859	PFAM glycosyl transferase family 9
AL497_RS11850	COG0156	8-amino-7-oxononanoate synthase activity
AL497_RS11865	COG0463	Glycosyl transferase, family 2
AL497_RS11870	COG2861	carbohydrate metabolic process
AL497_RS11875	COG4942	peptidase
AL497_RS11885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL497_RS11890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL497_RS11915	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL497_RS11925	COG2186	Transcriptional regulator
AL497_RS11945	COG3722	fumarate hydratase activity
AL497_RS11965	COG1566	PFAM secretion protein HlyD family protein
AL497_RS11970	COG0625	glutathione transferase activity
AL497_RS11980	COG3276	selenocysteine insertion sequence binding
AL497_RS11985	COG1454	alcohol dehydrogenase
AL497_RS11990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS11995	COG3977	Valine--pyruvate aminotransferase
AL497_RS12000	COG0366	Alpha amylase catalytic
AL497_RS12010	COG2992	FlgJ-related protein
AL497_RS12015	COG2207	Transcriptional regulator
AL497_RS12015	COG1609	Transcriptional regulator
AL497_RS12020	COG4214	carbohydrate transport
AL497_RS12030	COG4213	ABC transporter substrate-binding protein
AL497_RS12045	COG1070	Carbohydrate kinase
AL497_RS12050	COG4682	membrane
AL497_RS12055	COG3274	enterobacterial common antigen metabolic process
AL497_RS12080	COG1278	Cold shock
AL497_RS12085	COG2944	sequence-specific DNA binding
AL497_RS12090	COG2814	Major facilitator Superfamily
AL497_RS12110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL497_RS12120	COG1609	Transcriptional regulator
AL497_RS12125	COG2885	chlorophyll binding
AL497_RS12130	COG0243	molybdopterin cofactor binding
AL497_RS12135	COG0456	acetyltransferase
AL497_RS12140	COG2818	Glycosylase
AL497_RS12145	COG5571	outer membrane autotransporter
AL497_RS12155	COG2223	nitrite transmembrane transporter activity
AL497_RS12175	COG0747	negative chemotaxis
AL497_RS12180	COG0601	transmembrane transport
AL497_RS12185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL497_RS12190	COG0444	Belongs to the ABC transporter superfamily
AL497_RS12195	COG4608	Belongs to the ABC transporter superfamily
AL497_RS12215	COG2194	sulfuric ester hydrolase activity
AL497_RS12245	COG1215	transferase activity, transferring glycosyl groups
AL497_RS12250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AL497_RS12255	COG0457	Tetratricopeptide repeat
AL497_RS12255	COG3118	belongs to the thioredoxin family
AL497_RS12260	COG2199	diguanylate cyclase activity
AL497_RS12260	COG2200	EAL domain
AL497_RS12270	COG0612	Peptidase, M16
AL497_RS12280	COG2982	Protein involved in outer membrane biogenesis
AL497_RS12285	COG0477	Major facilitator Superfamily
AL497_RS12290	COG1295	ribonuclease BN
AL497_RS12295	COG0583	DNA-binding transcription factor activity
AL497_RS12300	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS12305	COG2197	response regulator
AL497_RS12315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL497_RS12325	COG1454	alcohol dehydrogenase
AL497_RS12330	COG0625	glutathione transferase activity
AL497_RS12335	COG1609	Transcriptional regulator
AL497_RS12340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL497_RS12345	COG2610	gluconate transmembrane transporter activity
AL497_RS12355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL497_RS12360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL497_RS12380	COG1959	2 iron, 2 sulfur cluster binding
AL497_RS12390	COG0589	response to stress
AL497_RS12400	COG0306	phosphate transporter
AL497_RS12405	COG2081	HI0933 family
AL497_RS12410	COG2239	Acts as a magnesium transporter
AL497_RS12430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL497_RS12435	COG0601	transmembrane transport
AL497_RS12440	COG0747	negative chemotaxis
AL497_RS12450	COG3479	Phenolic acid decarboxylase
AL497_RS12490	COG2091	lysine biosynthetic process via aminoadipic acid
AL497_RS12495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL497_RS12500	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS12510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL497_RS12545	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AL497_RS12545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL497_RS12555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL497_RS12575	COG0477	Major facilitator Superfamily
AL497_RS12585	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL497_RS12600	COG3714	YhhN family
AL497_RS12610	COG3776	membrane
AL497_RS12615	COG0742	ribosomal rna small subunit methyltransferase
AL497_RS12620	COG0552	protein localization to endoplasmic reticulum
AL497_RS12625	COG2884	Cell division ATP-binding protein ftsE
AL497_RS12630	COG2177	Part of the ABC transporter FtsEX involved in
AL497_RS12640	COG0683	leucine binding
AL497_RS12655	COG0683	leucine binding
AL497_RS12660	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL497_RS12670	COG0411	ABC transporter
AL497_RS12700	COG0584	glycerophosphoryl diester phosphodiesterase
AL497_RS12710	COG0405	Gamma-glutamyltransferase
AL497_RS12715	COG1247	-acetyltransferase
AL497_RS12725	COG0673	inositol 2-dehydrogenase activity
AL497_RS12730	COG1741	Belongs to the pirin family
AL497_RS12735	COG1609	Transcriptional regulator
AL497_RS12740	COG3265	gluconokinase activity
AL497_RS12745	COG2610	gluconate transmembrane transporter activity
AL497_RS12755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL497_RS12780	COG0058	SHG alpha-glucan phosphorylase activity
AL497_RS12785	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL497_RS12800	COG1349	DNA-binding transcription factor activity
AL497_RS12810	COG0058	SHG alpha-glucan phosphorylase activity
AL497_RS12815	COG1640	4-alpha-glucanotransferase
AL497_RS12820	COG2610	gluconate transmembrane transporter activity
AL497_RS12830	COG1040	competence protein
AL497_RS12855	COG1918	ferrous iron import across plasma membrane
AL497_RS12860	COG2183	response to ionizing radiation
AL497_RS12865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL497_RS12875	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS12880	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL497_RS12885	COG4948	Mandelate Racemase Muconate Lactonizing
AL497_RS12900	COG3254	rhamnose metabolic process
AL497_RS12905	COG0738	Major facilitator superfamily
AL497_RS12930	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL497_RS12935	COG1011	Hydrolase
AL497_RS12945	COG0494	nUDIX hydrolase
AL497_RS12955	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL497_RS12980	COG4796	Type ii and iii secretion system protein
AL497_RS13000	COG3266	domain, Protein
AL497_RS13005	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AL497_RS13010	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL497_RS13030	COG2146	nitrite reductase [NAD(P)H] activity
AL497_RS13035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL497_RS13040	COG0402	S-adenosylhomocysteine deaminase activity
AL497_RS13045	COG0738	Major facilitator superfamily
AL497_RS13060	COG2184	nucleotidyltransferase activity
AL497_RS13070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL497_RS13075	COG1289	transmembrane transporter activity
AL497_RS13085	COG1765	OsmC-like protein
AL497_RS13090	COG3954	Phosphoribulokinase
AL497_RS13100	COG0429	hydrolase of the alpha beta-hydrolase fold
AL497_RS13110	COG0488	(ABC) transporter
AL497_RS13125	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AL497_RS13130	COG1047	Peptidyl-prolyl cis-trans
AL497_RS13140	COG0545	Peptidyl-prolyl cis-trans isomerase
AL497_RS13150	COG2964	Protein conserved in bacteria
AL497_RS13205	COG0051	transcription antitermination factor activity, RNA binding
AL497_RS13230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL497_RS13245	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL497_RS13310	COG0201	protein transport
AL497_RS13325	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL497_RS13350	COG0789	Transcriptional regulator
AL497_RS13355	COG3036	rescue of stalled ribosome
AL497_RS13385	COG0758	DNA mediated transformation
AL497_RS13395	COG0551	DNA topoisomerase type I activity
AL497_RS13415	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL497_RS13450	COG0842	Transport permease protein
AL497_RS13455	COG1129	ABC transporter
AL497_RS13455	COG0842	Transport permease protein
AL497_RS13460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS13465	COG3706	GGDEF domain
AL497_RS13490	COG4869	propanediol catabolic process
AL497_RS13500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL497_RS13505	COG1882	Formate acetyltransferase
AL497_RS13520	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS13520	COG1454	alcohol dehydrogenase
AL497_RS13565	COG3716	PTS system mannose fructose sorbose family IID component
AL497_RS13570	COG3715	PTS system
AL497_RS13575	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS13575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS13595	COG0531	amino acid
AL497_RS13605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL497_RS13610	COG5457	Domain of unknown function (DUF1127)
AL497_RS13620	COG1566	PFAM secretion protein HlyD family protein
AL497_RS13645	COG1924	4 iron, 4 sulfur cluster binding
AL497_RS13650	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AL497_RS13660	COG2733	membrane
AL497_RS13670	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS13675	COG0523	cobalamin synthesis protein
AL497_RS13680	COG2879	small protein
AL497_RS13685	COG1966	Carbon starvation protein
AL497_RS13690	COG2831	hemolysin activation secretion protein
AL497_RS13695	COG3210	domain, Protein
AL497_RS13720	COG3210	domain, Protein
AL497_RS13750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL497_RS13755	COG2368	4-hydroxyphenylacetate
AL497_RS13775	COG3971	2-oxopent-4-enoate hydratase activity
AL497_RS13785	COG3384	dioxygenase
AL497_RS13790	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS13800	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL497_RS13810	COG1846	Transcriptional regulator
AL497_RS13825	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL497_RS13825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL497_RS13840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL497_RS13845	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS13850	COG0531	amino acid
AL497_RS13870	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL497_RS13885	COG3734	2-keto-3-deoxy-galactonokinase
AL497_RS13890	COG0800	Aldolase
AL497_RS13895	COG1737	Transcriptional regulator
AL497_RS13895	COG0837	glucose binding
AL497_RS13920	COG1484	DNA-dependent DNA replication
AL497_RS13935	COG2966	Psort location CytoplasmicMembrane, score
AL497_RS13950	COG2197	response regulator
AL497_RS13955	COG2197	response regulator
AL497_RS13960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL497_RS13965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS13970	COG4114	ferric iron reductase
AL497_RS13975	COG3706	GGDEF domain
AL497_RS14005	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AL497_RS14010	COG0456	acetyltransferase
AL497_RS14015	COG1011	Hydrolase
AL497_RS14025	COG2823	Periplasmic or secreted lipoprotein
AL497_RS14030	COG5487	UPF0391 membrane protein
AL497_RS14035	COG4667	esterase of the alpha-beta hydrolase superfamily
AL497_RS14040	COG0084	hydrolase, TatD family'
AL497_RS14070	COG3726	membrane protein affecting hemolysin expression
AL497_RS14080	COG0560	Phosphoserine phosphatase
AL497_RS14085	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AL497_RS14095	COG0488	(ABC) transporter
AL497_RS14105	COG0741	lytic transglycosylase activity
AL497_RS14125	COG3708	Transcriptional regulator
AL497_RS14125	COG2207	Transcriptional regulator
AL497_RS14130	COG3045	CreA protein
AL497_RS14135	COG0745	RESPONSE REGULATOR receiver
AL497_RS14140	COG2205	protein histidine kinase activity
AL497_RS14145	COG4452	Inner membrane protein CreD
AL497_RS14150	COG0745	RESPONSE REGULATOR receiver
AL497_RS14165	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AL497_RS14175	COG0527	aspartate kinase activity
AL497_RS14175	COG0460	homoserine dehydrogenase
AL497_RS14185	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL497_RS14195	COG1115	amino acid carrier protein
AL497_RS14200	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL497_RS14205	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL497_RS14215	COG1584	GPR1 FUN34 yaaH family protein
AL497_RS14235	COG0583	DNA-binding transcription factor activity
AL497_RS14275	COG3539	Fimbrial protein
AL497_RS14285	COG3188	usher protein
AL497_RS14300	COG3539	Fimbrial protein
AL497_RS14305	COG3121	Chaperone
AL497_RS14325	COG0583	DNA-binding transcription factor activity
AL497_RS14340	COG0196	riboflavin kinase activity
AL497_RS14350	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL497_RS14355	COG1047	Peptidyl-prolyl cis-trans
AL497_RS14370	COG0583	DNA-binding transcription factor activity
AL497_RS14380	COG2828	Protein conserved in bacteria
AL497_RS14385	COG0471	metal ion transport
AL497_RS14390	COG0471	metal ion transport
AL497_RS14395	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL497_RS14405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL497_RS14475	COG0505	Belongs to the CarA family
AL497_RS14530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL497_RS14540	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL497_RS14545	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL497_RS14560	COG3493	citrate carrier protein
AL497_RS14570	COG0564	pseudouridine synthase activity
AL497_RS14580	COG0417	DNA replication proofreading
AL497_RS14585	COG0235	Class ii aldolase
AL497_RS14605	COG0586	Pfam SNARE associated Golgi protein
AL497_RS14615	COG1178	ABC-type Fe3 transport system permease component
AL497_RS14635	COG2814	Major facilitator Superfamily
AL497_RS14640	COG2271	Major facilitator Superfamily
AL497_RS14645	COG0583	DNA-binding transcription factor activity
AL497_RS14655	COG0738	Major facilitator superfamily
AL497_RS14705	COG0028	Belongs to the TPP enzyme family
AL497_RS14735	COG0768	penicillin binding
AL497_RS14740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL497_RS14745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL497_RS14760	COG0772	Belongs to the SEDS family
AL497_RS14775	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL497_RS14785	COG0849	cell division
AL497_RS14790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL497_RS14810	COG0494	nUDIX hydrolase
AL497_RS14835	COG1459	type II secretion system
AL497_RS14840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL497_RS14845	COG4969	Belongs to the N-Me-Phe pilin family
AL497_RS14860	COG3725	Membrane protein required for beta-lactamase induction
AL497_RS14865	COG3940	Belongs to the glycosyl hydrolase 43 family
AL497_RS14870	COG2211	Major facilitator Superfamily
AL497_RS14875	COG1113	amino acid transport
AL497_RS14880	COG2186	Transcriptional regulator
AL497_RS14885	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL497_RS14890	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL497_RS14895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL497_RS14910	COG3064	Membrane
AL497_RS14915	COG1049	propionate catabolic process, 2-methylcitrate cycle
AL497_RS14935	COG0545	Peptidyl-prolyl cis-trans isomerase
AL497_RS14950	COG2132	Multicopper oxidase
AL497_RS14955	COG4993	Dehydrogenase
AL497_RS14965	COG0288	reversible hydration of carbon dioxide
AL497_RS14975	COG1131	(ABC) transporter
AL497_RS14980	COG0842	Transport permease protein
AL497_RS14985	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS14990	COG0726	polysaccharide deacetylase
AL497_RS14995	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AL497_RS15010	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL497_RS15035	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AL497_RS15040	COG1643	Atp-dependent helicase
AL497_RS15050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL497_RS15055	COG4774	siderophore transport
AL497_RS15060	COG1120	ATPase activity
AL497_RS15065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL497_RS15070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS15095	COG2860	membrane
AL497_RS15100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL497_RS15120	COG3835	regulator
AL497_RS15140	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL497_RS15145	COG0024	Methionine aminopeptidase
AL497_RS15170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL497_RS15185	COG0575	Belongs to the CDS family
AL497_RS15190	COG0750	zinc metalloprotease
AL497_RS15245	COG1982	Orn Lys Arg decarboxylase major
AL497_RS15250	COG0346	lactoylglutathione lyase activity
AL497_RS15255	COG0037	tRNA processing
AL497_RS15260	COG4568	rho-dependent transcription termination
AL497_RS15275	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL497_RS15280	COG3015	lipoprotein NlpE involved in copper resistance
AL497_RS15290	COG1720	tRNA m6t6A37 methyltransferase activity
AL497_RS15300	COG1464	Belongs to the NlpA lipoprotein family
AL497_RS15305	COG2011	ABC-type metal ion transport system permease component
AL497_RS15315	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL497_RS15350	COG0656	L-ascorbic acid biosynthetic process
AL497_RS15355	COG0583	DNA-binding transcription factor activity
AL497_RS15360	COG2814	Major facilitator Superfamily
AL497_RS15370	COG2226	methyltransferase
AL497_RS15375	COG1388	LysM domain
AL497_RS15375	COG0741	lytic transglycosylase activity
AL497_RS15385	COG2226	methyltransferase
AL497_RS15395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL497_RS15405	COG0583	DNA-binding transcription factor activity
AL497_RS15415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL497_RS15420	COG1960	acyl-CoA dehydrogenase activity
AL497_RS15430	COG0121	glutamine amidotransferase
AL497_RS15435	COG3034	peptidoglycan biosynthetic process
AL497_RS15455	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL497_RS15460	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL497_RS15475	COG2991	Protein conserved in bacteria
AL497_RS15490	COG0454	-acetyltransferase
AL497_RS15505	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL497_RS15525	COG1045	serine acetyltransferase
AL497_RS15540	COG0297	glycogen (starch) synthase activity
AL497_RS15540	COG0438	transferase activity, transferring glycosyl groups
AL497_RS15545	COG0438	transferase activity, transferring glycosyl groups
AL497_RS15550	COG0463	Glycosyl transferase, family 2
AL497_RS15570	COG1596	polysaccharide export
AL497_RS15580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL497_RS15595	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS15605	COG0583	DNA-binding transcription factor activity
AL497_RS15620	COG1802	Transcriptional regulator
AL497_RS15625	COG1113	amino acid transport
AL497_RS15630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL497_RS15635	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS15640	COG0579	oxidoreductase
AL497_RS15660	COG3188	usher protein
AL497_RS15665	COG3121	Chaperone
AL497_RS15715	COG0791	NLP P60 protein
AL497_RS15735	COG3639	organic phosphonate transmembrane transporter activity
AL497_RS15745	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AL497_RS15770	COG3188	usher protein
AL497_RS15790	COG2271	Major facilitator Superfamily
AL497_RS15795	COG0583	DNA-binding transcription factor activity
AL497_RS15800	COG0765	amino acid transport
AL497_RS15805	COG0765	amino acid transport
AL497_RS15815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS15830	COG0833	amino acid
AL497_RS15835	COG2040	homocysteine
AL497_RS15840	COG4521	taurine ABC transporter
AL497_RS15845	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL497_RS15850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL497_RS15855	COG2175	clavaminate synthase activity
AL497_RS15870	COG0113	porphobilinogen synthase activity
AL497_RS15875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL497_RS15885	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AL497_RS15920	COG1785	Belongs to the alkaline phosphatase family
AL497_RS15930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL497_RS15940	COG3416	Protein conserved in bacteria
AL497_RS15945	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL497_RS15955	COG4126	flavin adenine dinucleotide binding
AL497_RS15970	COG1940	carbohydrate kinase activity
AL497_RS15975	COG0419	ATPase involved in DNA repair
AL497_RS15980	COG0420	3'-5' exonuclease activity
AL497_RS16005	COG0366	Alpha amylase catalytic
AL497_RS16010	COG0583	DNA-binding transcription factor activity
AL497_RS16015	COG1335	isochorismatase
AL497_RS16025	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AL497_RS16030	COG0450	alkyl hydroperoxide reductase
AL497_RS16050	COG1862	Preprotein translocase
AL497_RS16060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL497_RS16075	COG3248	Nucleoside-binding outer membrane protein
AL497_RS16080	COG4238	major outer membrane lipoprotein
AL497_RS16090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL497_RS16090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL497_RS16110	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL497_RS16115	COG0667	Aldo Keto reductase
AL497_RS16125	COG0142	geranyltranstransferase activity
AL497_RS16150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL497_RS16165	COG2831	hemolysin activation secretion protein
AL497_RS16170	COG0736	holo-[acyl-carrier-protein] synthase activity
AL497_RS16180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL497_RS16185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL497_RS16195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL497_RS16210	COG1136	(ABC) transporter
AL497_RS16220	COG2177	Part of the ABC transporter FtsEX involved in
AL497_RS16250	COG2814	Major facilitator Superfamily
AL497_RS16265	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL497_RS16270	COG1845	cytochrome c oxidase, subunit III
AL497_RS16275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL497_RS16280	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL497_RS16285	COG2223	nitrite transmembrane transporter activity
AL497_RS16290	COG3056	Lipoprotein
AL497_RS16300	COG0271	Belongs to the BolA IbaG family
AL497_RS16330	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL497_RS16335	COG0776	regulation of translation
AL497_RS16340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL497_RS16350	COG1555	photosystem II stabilization
AL497_RS16355	COG0824	Thioesterase
AL497_RS16365	COG4533	DNA binding
AL497_RS16380	COG1522	sequence-specific DNA binding
AL497_RS16385	COG1132	(ABC) transporter
AL497_RS16390	COG1132	(ABC) transporter
AL497_RS16395	COG0347	Belongs to the P(II) protein family
AL497_RS16400	COG0004	ammonium transporteR
AL497_RS16405	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL497_RS16410	COG0583	DNA-binding transcription factor activity
AL497_RS16415	COG1946	Acyl-CoA thioesterase
AL497_RS16420	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL497_RS16425	COG3695	enzyme binding
AL497_RS16455	COG2364	Membrane
AL497_RS16460	COG5507	3-demethylubiquinone-9 3-methyltransferase
AL497_RS16465	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL497_RS16475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL497_RS16495	COG0110	maltose O-acetyltransferase activity
AL497_RS16510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL497_RS16515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS16520	COG1309	transcriptional regulator
AL497_RS16525	COG1196	nuclear chromosome segregation
AL497_RS16525	COG3264	Mechanosensitive ion channel
AL497_RS16535	COG3923	Primosomal replication protein n
AL497_RS16540	COG2832	Protein of unknown function (DUF454)
AL497_RS16580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL497_RS16585	COG4651	solute:proton antiporter activity
AL497_RS16585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL497_RS16590	COG2223	nitrite transmembrane transporter activity
AL497_RS16600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL497_RS16605	COG3735	TraB family
AL497_RS16620	COG1585	Membrane protein implicated in regulation of membrane protease activity
AL497_RS16625	COG0330	HflC and HflK could
AL497_RS16630	COG4619	ABC transporter
AL497_RS16635	COG0390	transport system, permease component
AL497_RS16640	COG3118	belongs to the thioredoxin family
AL497_RS16645	COG0300	oxidoreductase activity
AL497_RS16650	COG2755	lipolytic protein G-D-S-L family
AL497_RS16655	COG4181	ATPase activity
AL497_RS16660	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL497_RS16680	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL497_RS16685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL497_RS16700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL497_RS16710	COG2501	S4 domain
AL497_RS16750	COG0583	DNA-binding transcription factor activity
AL497_RS16765	COG1560	Kdo2-lipid A biosynthetic process
AL497_RS16775	COG1902	pentaerythritol trinitrate reductase activity
AL497_RS16780	COG3710	Transcriptional regulator
AL497_RS16790	COG0531	amino acid
AL497_RS16795	COG1982	Orn Lys Arg decarboxylase major
AL497_RS16800	COG3104	oligopeptide transport
AL497_RS16810	COG0402	S-adenosylhomocysteine deaminase activity
AL497_RS16815	COG0549	Belongs to the carbamate kinase family
AL497_RS16820	COG1304	FMN binding
AL497_RS16825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL497_RS16835	COG0666	response to abiotic stimulus
AL497_RS16845	COG0583	DNA-binding transcription factor activity
AL497_RS16860	COG1566	PFAM secretion protein HlyD family protein
AL497_RS16880	COG1473	amidohydrolase
AL497_RS16885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS16890	COG0667	Aldo Keto reductase
AL497_RS16945	COG0531	amino acid
AL497_RS16955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL497_RS16960	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS16970	COG1252	NADH dehydrogenase
AL497_RS16985	COG1113	amino acid transport
AL497_RS16990	COG0668	transmembrane transport
AL497_RS16995	COG0477	Major facilitator Superfamily
AL497_RS17015	COG0778	Nitroreductase
AL497_RS17020	COG2315	Protein conserved in bacteria
AL497_RS17050	COG3698	Phosphodiester glycosidase
AL497_RS17085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL497_RS17105	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS17115	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS17120	COG1129	ABC transporter
AL497_RS17130	COG1879	ABC-type sugar transport system periplasmic component
AL497_RS17135	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL497_RS17140	COG2390	Transcriptional regulator
AL497_RS17150	COG3959	Transketolase, thiamine diphosphate binding domain
AL497_RS17155	COG3958	Transketolase
AL497_RS17160	COG4771	TonB-dependent receptor
AL497_RS17170	COG2382	esterase
AL497_RS17175	COG3251	PFAM MbtH domain protein
AL497_RS17180	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AL497_RS17180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL497_RS17185	COG1120	ATPase activity
AL497_RS17190	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS17195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS17200	COG0477	Major facilitator Superfamily
AL497_RS17210	COG4592	Periplasmic binding protein
AL497_RS17215	COG1169	isochorismate synthase
AL497_RS17220	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL497_RS17225	COG3433	isochorismatase activity
AL497_RS17225	COG1535	isochorismatase
AL497_RS17230	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS17240	COG1966	Carbon starvation protein
AL497_RS17245	COG2879	small protein
AL497_RS17265	COG1129	ABC transporter
AL497_RS17270	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL497_RS17295	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AL497_RS17305	COG0436	Aminotransferase
AL497_RS17310	COG1475	DNA binding
AL497_RS17315	COG3969	phosphoadenosine phosphosulfate
AL497_RS17320	COG0583	DNA-binding transcription factor activity
AL497_RS17330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL497_RS17340	COG3634	alkyl hydroperoxide reductase activity
AL497_RS17350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL497_RS17355	COG3719	Belongs to the RNase T2 family
AL497_RS17360	COG3069	C4-dicarboxylate transmembrane transporter activity
AL497_RS17380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL497_RS17395	COG0583	DNA-binding transcription factor activity
AL497_RS17410	COG1686	Belongs to the peptidase S11 family
AL497_RS17415	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL497_RS17420	COG0772	Belongs to the SEDS family
AL497_RS17425	COG0768	penicillin binding
AL497_RS17435	COG0799	negative regulation of ribosome biogenesis
AL497_RS17440	COG0406	alpha-ribazole phosphatase activity
AL497_RS17450	COG1466	dna polymerase III delta subunit
AL497_RS17465	COG2888	peptidyl-tyrosine sulfation
AL497_RS17475	COG2831	hemolysin activation secretion protein
AL497_RS17480	COG1126	abc transporter atp-binding protein
AL497_RS17485	COG0765	amino acid transport
AL497_RS17490	COG0765	amino acid transport
AL497_RS17520	COG1702	phosphate starvation-inducible protein PhoH
AL497_RS17530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL497_RS17570	COG0367	asparagine synthase
AL497_RS17575	COG0647	UMP catabolic process
AL497_RS17580	COG1940	carbohydrate kinase activity
AL497_RS17580	COG1846	Transcriptional regulator
AL497_RS17585	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL497_RS17630	COG1053	succinate dehydrogenase
AL497_RS17635	COG0583	DNA-binding transcription factor activity
AL497_RS17640	COG0735	belongs to the Fur family
AL497_RS17655	COG0596	Alpha beta hydrolase
AL497_RS17665	COG0033	Phosphoglucomutase
AL497_RS17670	COG0745	RESPONSE REGULATOR receiver
AL497_RS17675	COG2205	protein histidine kinase activity
AL497_RS17705	COG0415	Belongs to the DNA photolyase family
AL497_RS17715	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL497_RS17720	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL497_RS17725	COG1984	allophanate hydrolase subunit 2
AL497_RS17755	COG0372	Belongs to the citrate synthase family
AL497_RS17770	COG2009	succinate dehydrogenase
AL497_RS17775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL497_RS17780	COG1053	succinate dehydrogenase
AL497_RS17785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL497_RS17790	COG0567	Dehydrogenase, E1 component
AL497_RS17795	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL497_RS17810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL497_RS17820	COG1271	oxidase subunit
AL497_RS17825	COG1294	oxidase, subunit
AL497_RS17830	COG4890	Cyd operon protein YbgT
AL497_RS17835	COG3790	cyd operon protein YbgE
AL497_RS17840	COG0824	Thioesterase
AL497_RS17845	COG0811	peptide transport
AL497_RS17850	COG0848	biopolymer transport protein
AL497_RS17855	COG3064	Membrane
AL497_RS17865	COG2885	chlorophyll binding
AL497_RS17870	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL497_RS17910	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL497_RS17920	COG1230	cation diffusion facilitator family transporter
AL497_RS17930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL497_RS17945	COG2017	converts alpha-aldose to the beta-anomer
AL497_RS17955	COG1085	galactose-1-phosphate uridylyltransferase
AL497_RS17960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL497_RS17965	COG1119	ATPase activity
AL497_RS17970	COG2005	Transcriptional regulator
AL497_RS17970	COG3585	molybdate ion transport
AL497_RS17980	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL497_RS17985	COG4149	molybdate abc transporter
AL497_RS17995	COG0561	phosphatase activity
AL497_RS18020	COG2200	EAL domain
AL497_RS18025	COG0789	Transcriptional regulator
AL497_RS18050	COG1595	DNA-templated transcription, initiation
AL497_RS18060	COG4677	pectinesterase activity
AL497_RS18100	COG1881	PFAM PEBP family protein
AL497_RS18105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL497_RS18120	COG2226	methyltransferase
AL497_RS18145	COG0745	RESPONSE REGULATOR receiver
AL497_RS18170	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL497_RS18180	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL497_RS18185	COG0314	molybdopterin synthase activity
AL497_RS18190	COG0670	Belongs to the BI1 family
AL497_RS18195	COG0392	lysyltransferase activity
AL497_RS18200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL497_RS18205	COG3568	Endonuclease Exonuclease Phosphatase
AL497_RS18215	COG0842	Transport permease protein
AL497_RS18220	COG0842	Transport permease protein
AL497_RS18225	COG1131	(ABC) transporter
AL497_RS18235	COG1309	transcriptional regulator
AL497_RS18240	COG0513	Belongs to the DEAD box helicase family
AL497_RS18250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL497_RS18260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL497_RS18270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL497_RS18280	COG0668	transmembrane transport
AL497_RS18285	COG1126	abc transporter atp-binding protein
AL497_RS18290	COG0765	amino acid transport
AL497_RS18295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS18310	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL497_RS18315	COG2194	sulfuric ester hydrolase activity
AL497_RS18325	COG1321	iron dependent repressor
AL497_RS18330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AL497_RS18335	COG0667	Aldo Keto reductase
AL497_RS18340	COG2723	6-phospho-beta-galactosidase activity
AL497_RS18345	COG2188	Transcriptional regulator
AL497_RS18350	COG1376	ErfK ybiS ycfS ynhG family protein
AL497_RS18360	COG0488	(ABC) transporter
AL497_RS18370	COG2271	Major facilitator Superfamily
AL497_RS18375	COG1609	Transcriptional regulator
AL497_RS18385	COG0561	phosphatase activity
AL497_RS18390	COG1882	Formate acetyltransferase
AL497_RS18395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL497_RS18400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL497_RS18405	COG0303	'Molybdopterin
AL497_RS18415	COG1446	asparaginase
AL497_RS18425	COG0747	negative chemotaxis
AL497_RS18450	COG2133	pyrroloquinoline quinone binding
AL497_RS18455	COG0625	glutathione transferase activity
AL497_RS18460	COG1686	Belongs to the peptidase S11 family
AL497_RS18465	COG1349	DNA-binding transcription factor activity
AL497_RS18470	COG0671	phosphoesterase, PA-phosphatase related
AL497_RS18480	COG2814	Major facilitator Superfamily
AL497_RS18485	COG0561	phosphatase activity
AL497_RS18490	COG0738	Major facilitator superfamily
AL497_RS18495	COG3226	Transcriptional regulator
AL497_RS18500	COG0300	oxidoreductase activity
AL497_RS18540	COG0778	Nitroreductase
AL497_RS18555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL497_RS18560	COG3842	ATPase activity
AL497_RS18565	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL497_RS18570	COG1177	transmembrane transport
AL497_RS18580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL497_RS18585	COG0745	RESPONSE REGULATOR receiver
AL497_RS18590	COG5002	protein histidine kinase activity
AL497_RS18595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS18600	COG4160	amino acid transport
AL497_RS18605	COG4215	(ABC) transporter
AL497_RS18610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS18615	COG1126	abc transporter atp-binding protein
AL497_RS18625	COG2067	long-chain fatty acid transport protein
AL497_RS18635	COG5001	Diguanylate cyclase
AL497_RS18635	COG4251	negative regulation of phosphorylation
AL497_RS18635	COG3706	GGDEF domain
AL497_RS18635	COG2203	Gaf domain
AL497_RS18640	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL497_RS18650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL497_RS18655	COG0702	epimerase
AL497_RS18660	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL497_RS18665	COG0028	Belongs to the TPP enzyme family
AL497_RS18675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL497_RS18685	COG2431	L-lysine efflux transmembrane transporter activity
AL497_RS18695	COG3593	DNA synthesis involved in DNA repair
AL497_RS18700	COG2990	Protein conserved in bacteria
AL497_RS18705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS18715	COG1278	Cold shock
AL497_RS18725	COG0542	response to heat
AL497_RS18740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL497_RS18745	COG4988	ABC transporter
AL497_RS18750	COG0492	ferredoxin-NADP+ reductase activity
AL497_RS18775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL497_RS18790	COG0437	4 iron, 4 sulfur cluster binding
AL497_RS18795	COG3302	dmso reductase anchor subunit
AL497_RS18800	COG0477	Major facilitator Superfamily
AL497_RS18805	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL497_RS18810	COG1882	Formate acetyltransferase
AL497_RS18815	COG2116	formate transmembrane transporter activity
AL497_RS18820	COG1944	ATP diphosphatase activity
AL497_RS18845	COG0539	negative regulation of cytoplasmic translation
AL497_RS18855	COG2333	competence protein COMEC
AL497_RS18855	COG0658	competence protein
AL497_RS18870	COG3214	Protein conserved in bacteria
AL497_RS18875	COG2835	tetraacyldisaccharide 4'-kinase activity
AL497_RS18885	COG3173	Aminoglycoside phosphotransferase
AL497_RS18890	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL497_RS18895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL497_RS18905	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AL497_RS18915	COG2989	Protein conserved in bacteria
AL497_RS18925	COG3108	Peptidase M15
AL497_RS18930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL497_RS18935	COG1448	Aminotransferase
AL497_RS18940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL497_RS18950	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL497_RS18960	COG0308	aminopeptidase N
AL497_RS18970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL497_RS18975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS18980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL497_RS18985	COG0431	NADPH-dependent FMN reductase
AL497_RS19000	COG0633	Ferredoxin
AL497_RS19000	COG3217	Mosc domain protein beta barrel domain protein
AL497_RS19010	COG0488	(ABC) transporter
AL497_RS19015	COG2995	paraquat-inducible protein a
AL497_RS19020	COG3008	intermembrane lipid transfer
AL497_RS19020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL497_RS19025	COG3009	Protein conserved in bacteria
AL497_RS19035	COG3130	regulation of translation
AL497_RS19045	COG1067	ATP-dependent peptidase activity
AL497_RS19065	COG3070	regulator of competence-specific genes
AL497_RS19070	COG1289	transmembrane transporter activity
AL497_RS19075	COG3304	Inner membrane component domain
AL497_RS19080	COG0210	DNA helicase
AL497_RS19090	COG1832	CoA-binding protein
AL497_RS19105	COG2274	protein secretion by the type I secretion system
AL497_RS19110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS19115	COG0438	transferase activity, transferring glycosyl groups
AL497_RS19145	COG0670	Belongs to the BI1 family
AL497_RS19160	COG0583	DNA-binding transcription factor activity
AL497_RS19175	COG0583	DNA-binding transcription factor activity
AL497_RS19225	COG1360	Flagellar Motor Protein
AL497_RS19230	COG2198	Histidine kinase
AL497_RS19230	COG0643	Histidine kinase
AL497_RS19235	COG0835	chemotaxis
AL497_RS19240	COG0840	transmembrane signaling receptor activity
AL497_RS19245	COG0840	transmembrane signaling receptor activity
AL497_RS19250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL497_RS19260	COG0745	RESPONSE REGULATOR receiver
AL497_RS19265	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL497_RS19270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL497_RS19275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL497_RS19285	COG3418	PFAM FlgN family protein
AL497_RS19290	COG2747	anti-sigma28 factor FlgM
AL497_RS19300	COG1815	bacterial-type flagellum-dependent cell motility
AL497_RS19305	COG1558	bacterial-type flagellum-dependent cell motility
AL497_RS19310	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL497_RS19325	COG4786	Flagellar basal body rod
AL497_RS19345	COG1256	bacterial-type flagellum assembly
AL497_RS19385	COG2814	Major facilitator Superfamily
AL497_RS19395	COG1414	Transcriptional regulator
AL497_RS19400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL497_RS19405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL497_RS19475	COG2882	bacterial-type flagellum organization
AL497_RS19480	COG1157	protein secretion by the type III secretion system
AL497_RS19490	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL497_RS19495	COG1766	The M ring may be actively involved in energy transduction
AL497_RS19500	COG1677	Flagellar hook-basal body complex protein FliE
AL497_RS19535	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL497_RS19550	COG1191	sigma factor activity
AL497_RS19590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL497_RS19595	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS19600	COG4638	Rieske (2fe-2S)
AL497_RS19605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL497_RS19615	COG0473	3-isopropylmalate dehydrogenase activity
AL497_RS19620	COG0583	DNA-binding transcription factor activity
AL497_RS19625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL497_RS19630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL497_RS19635	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS19640	COG1917	Cupin 2, conserved barrel domain protein
AL497_RS19640	COG1396	sequence-specific DNA binding
AL497_RS19645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AL497_RS19650	COG0174	glutamine synthetase
AL497_RS19660	COG0531	amino acid
AL497_RS19720	COG3729	General stress protein
AL497_RS19730	COG2233	PERMEase
AL497_RS19765	COG1309	transcriptional regulator
AL497_RS19780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL497_RS19785	COG0628	permease
AL497_RS19795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL497_RS19805	COG2822	iron ion transport
AL497_RS19815	COG1702	phosphate starvation-inducible protein PhoH
AL497_RS19825	COG1335	isochorismatase
AL497_RS19835	COG0583	DNA-binding transcription factor activity
AL497_RS19865	COG3381	protein complex oligomerization
AL497_RS19905	COG5645	(Lipo)protein
AL497_RS19920	COG1560	Kdo2-lipid A biosynthetic process
AL497_RS19965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL497_RS19975	COG0673	inositol 2-dehydrogenase activity
AL497_RS19985	COG2814	Major facilitator Superfamily
AL497_RS19990	COG0583	DNA-binding transcription factor activity
AL497_RS19995	COG1530	ribonuclease E activity
AL497_RS20015	COG1399	metal-binding, possibly nucleic acid-binding protein
AL497_RS20035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL497_RS20040	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS20050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL497_RS20055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL497_RS20060	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL497_RS20070	COG0470	DNA polymerase III
AL497_RS20075	COG0084	hydrolase, TatD family'
AL497_RS20080	COG1263	PTS System
AL497_RS20080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS20085	COG0537	adenosine 5'-monophosphoramidase activity
AL497_RS20090	COG5633	Lipoprotein
AL497_RS20125	COG1252	NADH dehydrogenase
AL497_RS20130	COG3134	Outer membrane lipoprotein
AL497_RS20140	COG1309	transcriptional regulator
AL497_RS20150	COG1376	ErfK ybiS ycfS ynhG family protein
AL497_RS20150	COG1388	LysM domain
AL497_RS20155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL497_RS20160	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL497_RS20165	COG1136	(ABC) transporter
AL497_RS20170	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL497_RS20180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL497_RS20185	COG2390	Transcriptional regulator
AL497_RS20200	COG3395	kinase activity
AL497_RS20215	COG0698	ribose 5-phosphate isomerase
AL497_RS20220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL497_RS20225	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL497_RS20235	COG0318	PFAM AMP-dependent synthetase and ligase
AL497_RS20245	COG1177	transmembrane transport
AL497_RS20265	COG1943	Transposase
AL497_RS20275	COG2850	peptidyl-arginine hydroxylation
AL497_RS20290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL497_RS20310	COG1187	pseudouridine synthase activity
AL497_RS20315	COG0538	isocitrate dehydrogenase activity
AL497_RS20350	COG1403	HNH endonuclease
AL497_RS20355	COG3272	Protein of unknown function (DUF1722)
AL497_RS20360	COG0789	Transcriptional regulator
AL497_RS20370	COG4977	sequence-specific DNA binding
AL497_RS20375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL497_RS20400	COG3122	Protein conserved in bacteria
AL497_RS20415	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AL497_RS20420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS20425	COG3477	response to acidic pH
AL497_RS20430	COG0012	GTP binding
AL497_RS20445	COG0659	secondary active sulfate transmembrane transporter activity
AL497_RS20480	COG2890	protein-(glutamine-N5) methyltransferase activity
AL497_RS20500	COG0387	Pfam Sodium calcium exchanger
AL497_RS20505	COG4572	Cation transport regulator
AL497_RS20510	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AL497_RS20520	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL497_RS20525	COG3707	response regulator
AL497_RS20530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL497_RS20540	COG1116	anion transmembrane transporter activity
AL497_RS20545	COG2146	nitrite reductase [NAD(P)H] activity
AL497_RS20545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL497_RS20550	COG0243	molybdopterin cofactor binding
AL497_RS20555	COG4932	domain protein
AL497_RS20560	COG2197	response regulator
AL497_RS20565	COG3850	Histidine kinase
AL497_RS20570	COG2223	nitrite transmembrane transporter activity
AL497_RS20575	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL497_RS20580	COG1140	nitrate reductase beta subunit
AL497_RS20585	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL497_RS20590	COG2181	nitrate reductase activity
AL497_RS20600	COG1522	sequence-specific DNA binding
AL497_RS20630	COG0788	formyltetrahydrofolate deformylase activity
AL497_RS20640	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL497_RS20645	COG0745	RESPONSE REGULATOR receiver
AL497_RS20650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL497_RS20665	COG1454	alcohol dehydrogenase
AL497_RS20665	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS20670	COG2095	MarC family integral membrane protein
AL497_RS20680	COG0601	transmembrane transport
AL497_RS20685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL497_RS20690	COG0444	Belongs to the ABC transporter superfamily
AL497_RS20700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL497_RS20725	COG0823	Involved in the tonB-independent uptake of proteins
AL497_RS20765	COG2135	peptidase activity
AL497_RS20770	COG2350	Protein conserved in bacteria
AL497_RS20775	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL497_RS20780	COG3001	Fructosamine kinase
AL497_RS20790	COG1105	Belongs to the carbohydrate kinase PfkB family
AL497_RS20795	COG3137	Salt-induced outer membrane protein
AL497_RS20820	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL497_RS20830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL497_RS20830	COG0072	phenylalanine-tRNA ligase activity
AL497_RS20850	COG0583	DNA-binding transcription factor activity
AL497_RS20870	COG0386	Belongs to the glutathione peroxidase family
AL497_RS20880	COG0791	NLP P60 protein
AL497_RS20890	COG4256	Hemin uptake protein
AL497_RS20895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL497_RS20910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL497_RS20910	COG0574	Belongs to the PEP-utilizing enzyme family
AL497_RS20920	COG0628	permease
AL497_RS20925	COG0277	FAD linked oxidase domain protein
AL497_RS20925	COG0247	lactate metabolic process
AL497_RS20930	COG2050	protein possibly involved in aromatic compounds catabolism
AL497_RS20935	COG3422	double-strand break repair
AL497_RS20940	COG2261	transglycosylase associated protein
AL497_RS20955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL497_RS20965	COG0316	Belongs to the HesB IscA family
AL497_RS20970	COG0719	Fe-S assembly protein
AL497_RS20975	COG0396	ATPase activity
AL497_RS20980	COG0719	Fe-S assembly protein
AL497_RS20995	COG1376	ErfK ybiS ycfS ynhG family protein
AL497_RS21020	COG1082	Xylose isomerase domain protein TIM barrel
AL497_RS21020	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AL497_RS21025	COG2271	Major facilitator Superfamily
AL497_RS21030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL497_RS21040	COG1120	ATPase activity
AL497_RS21045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS21050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL497_RS21075	COG0583	DNA-binding transcription factor activity
AL497_RS21080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS21100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL497_RS21105	COG1116	anion transmembrane transporter activity
AL497_RS21120	COG1120	ATPase activity
AL497_RS21125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS21130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS21150	COG0765	amino acid transport
AL497_RS21155	COG1126	abc transporter atp-binding protein
AL497_RS21165	COG1473	amidohydrolase
AL497_RS21170	COG1683	Conserved Protein
AL497_RS21175	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS21180	COG2378	regulation of single-species biofilm formation
AL497_RS21200	COG1280	lysine exporter protein (LysE YggA)
AL497_RS21230	COG3590	peptidase
AL497_RS21240	COG2207	Transcriptional regulator
AL497_RS21250	COG0251	oxidation-reduction process
AL497_RS21255	COG1309	transcriptional regulator
AL497_RS21275	COG0406	alpha-ribazole phosphatase activity
AL497_RS21280	COG1396	sequence-specific DNA binding
AL497_RS21285	COG0456	acetyltransferase
AL497_RS21305	COG3383	formate dehydrogenase (NAD+) activity
AL497_RS21310	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL497_RS21320	COG1175	transmembrane transport
AL497_RS21350	COG1138	Cytochrome C-type biogenesis protein
AL497_RS21380	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS21385	COG2610	gluconate transmembrane transporter activity
AL497_RS21390	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL497_RS21400	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL497_RS21410	COG0583	DNA-binding transcription factor activity
AL497_RS21425	COG4993	Dehydrogenase
AL497_RS21435	COG4608	Belongs to the ABC transporter superfamily
AL497_RS21440	COG0444	Belongs to the ABC transporter superfamily
AL497_RS21465	COG0346	lactoylglutathione lyase activity
AL497_RS21470	COG1349	DNA-binding transcription factor activity
AL497_RS21500	COG2233	PERMEase
AL497_RS21505	COG0493	'glutamate synthase
AL497_RS21505	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS21510	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS21515	COG0402	S-adenosylhomocysteine deaminase activity
AL497_RS21520	COG0493	'glutamate synthase
AL497_RS21520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL497_RS21525	COG2068	MobA-Related Protein
AL497_RS21530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL497_RS21535	COG3608	succinylglutamate desuccinylase aspartoacylase
AL497_RS21535	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AL497_RS21540	COG0549	Belongs to the carbamate kinase family
AL497_RS21550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL497_RS21555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL497_RS21560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL497_RS21565	COG3829	transcription factor binding
AL497_RS21575	COG2223	nitrite transmembrane transporter activity
AL497_RS21635	COG0534	Mate efflux family protein
AL497_RS21640	COG0307	riboflavin synthase, alpha
AL497_RS21645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL497_RS21650	COG2814	Major facilitator Superfamily
AL497_RS21655	COG0583	DNA-binding transcription factor activity
AL497_RS21670	COG2814	Major facilitator Superfamily
AL497_RS21680	COG3708	Transcriptional regulator
AL497_RS21680	COG2207	Transcriptional regulator
AL497_RS21685	COG0791	NLP P60 protein
AL497_RS21690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL497_RS21700	COG0346	lactoylglutathione lyase activity
AL497_RS21705	COG1902	pentaerythritol trinitrate reductase activity
AL497_RS21710	COG1309	transcriptional regulator
AL497_RS21715	COG3313	Fe-S protein
AL497_RS21720	COG4989	oxidoreductase activity
AL497_RS21725	COG2032	superoxide dismutase activity
AL497_RS21730	COG1289	transmembrane transporter activity
AL497_RS21735	COG1566	PFAM secretion protein HlyD family protein
AL497_RS21750	COG3706	GGDEF domain
AL497_RS21765	COG3895	Periplasmic Protein
AL497_RS21780	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL497_RS21785	COG0625	glutathione transferase activity
AL497_RS21800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL497_RS21810	COG4659	FMN binding
AL497_RS21845	COG2723	6-phospho-beta-galactosidase activity
AL497_RS21865	COG5562	phage envelope protein
AL497_RS21885	COG0425	Belongs to the sulfur carrier protein TusA family
AL497_RS21890	COG2391	methyltransferase activity
AL497_RS21900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL497_RS21905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL497_RS21905	COG1263	PTS System
AL497_RS21910	COG1609	Transcriptional regulator
AL497_RS21915	COG5339	Protein conserved in bacteria
AL497_RS21920	COG1482	cell wall glycoprotein biosynthetic process
AL497_RS21925	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AL497_RS21925	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AL497_RS21940	COG2205	protein histidine kinase activity
AL497_RS21950	COG0745	RESPONSE REGULATOR receiver
AL497_RS21955	COG3136	membrane protein required for alginate biosynthesis
AL497_RS21965	COG0531	amino acid
AL497_RS21985	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL497_RS21990	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL497_RS22005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL497_RS22010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL497_RS22025	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL497_RS22030	COG1473	amidohydrolase
AL497_RS22040	COG0583	DNA-binding transcription factor activity
AL497_RS22045	COG2840	Smr protein MutS2
AL497_RS22050	COG1414	Transcriptional regulator
AL497_RS22060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL497_RS22065	COG0183	Belongs to the thiolase family
AL497_RS22075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL497_RS22080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL497_RS22090	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AL497_RS22090	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AL497_RS22115	COG4565	transcriptional regulatory protein
AL497_RS22120	COG3290	protein histidine kinase activity
AL497_RS22125	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL497_RS22140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL497_RS22150	COG0679	Auxin Efflux Carrier
AL497_RS22180	COG0628	permease
AL497_RS22200	COG3300	MHYT domain
AL497_RS22200	COG5001	Diguanylate cyclase
AL497_RS22205	COG3591	Belongs to the peptidase S1B family
AL497_RS22225	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL497_RS22230	COG2814	Major facilitator Superfamily
AL497_RS22235	COG0583	DNA-binding transcription factor activity
AL497_RS22240	COG1940	carbohydrate kinase activity
AL497_RS22245	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL497_RS22260	COG3302	dmso reductase anchor subunit
AL497_RS22265	COG0437	4 iron, 4 sulfur cluster binding
AL497_RS22270	COG0243	molybdopterin cofactor binding
AL497_RS22285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL497_RS22300	COG2271	Major facilitator Superfamily
AL497_RS22305	COG4948	Mandelate Racemase Muconate Lactonizing
AL497_RS22310	COG1063	alcohol dehydrogenase
AL497_RS22315	COG0477	Major facilitator Superfamily
AL497_RS22320	COG0246	Mannitol dehydrogenase
AL497_RS22330	COG1802	Transcriptional regulator
AL497_RS22335	COG4221	oxidoreductase activity
AL497_RS22340	COG0339	signal peptide processing
AL497_RS22350	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL497_RS22355	COG2223	nitrite transmembrane transporter activity
AL497_RS22380	COG2199	diguanylate cyclase activity
AL497_RS22380	COG2203	Gaf domain
AL497_RS22405	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL497_RS22415	COG2814	Major facilitator Superfamily
AL497_RS22420	COG0697	spore germination
AL497_RS22435	COG1846	Transcriptional regulator
AL497_RS22455	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS22475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL497_RS22485	COG3395	kinase activity
AL497_RS22490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL497_RS22495	COG1349	DNA-binding transcription factor activity
AL497_RS22500	COG0583	DNA-binding transcription factor activity
AL497_RS22505	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS22520	COG2199	diguanylate cyclase activity
AL497_RS22545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL497_RS22550	COG2271	Major facilitator Superfamily
AL497_RS22555	COG3622	Belongs to the hyi family
AL497_RS22560	COG0235	Class ii aldolase
AL497_RS22565	COG3395	kinase activity
AL497_RS22570	COG1349	DNA-binding transcription factor activity
AL497_RS22600	COG0697	spore germination
AL497_RS22605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL497_RS22610	COG0477	Major facilitator Superfamily
AL497_RS22620	COG2070	2-Nitropropane dioxygenase
AL497_RS22625	COG2011	ABC-type metal ion transport system permease component
AL497_RS22645	COG4628	conserved protein (DUF2132)
AL497_RS22650	COG2207	Transcriptional regulator
AL497_RS22675	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS22680	COG3729	General stress protein
AL497_RS22685	COG3685	Protein conserved in bacteria
AL497_RS22700	COG1271	oxidase subunit
AL497_RS22705	COG1294	oxidase, subunit
AL497_RS22730	COG2323	membrane
AL497_RS22740	COG3111	PFAM Bacterial OB fold (BOF) protein
AL497_RS22750	COG0626	cystathionine gamma-synthase activity
AL497_RS22770	COG2610	gluconate transmembrane transporter activity
AL497_RS22775	COG1312	Catalyzes the dehydration of D-mannonate
AL497_RS22780	COG0401	homolog of Blt101
AL497_RS22790	COG4529	Protein conserved in bacteria
AL497_RS22805	COG2814	Major facilitator Superfamily
AL497_RS22815	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL497_RS22820	COG0588	phosphoglycerate mutase activity
AL497_RS22830	COG2723	6-phospho-beta-galactosidase activity
AL497_RS22840	COG4580	involved in the transport of maltose and maltodextrins
AL497_RS22845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS22850	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS22855	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS22860	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL497_RS22865	COG1940	carbohydrate kinase activity
AL497_RS22870	COG1609	Transcriptional regulator
AL497_RS22880	COG0667	Aldo Keto reductase
AL497_RS22885	COG0667	Aldo Keto reductase
AL497_RS22890	COG0667	Aldo Keto reductase
AL497_RS22915	COG0656	L-ascorbic acid biosynthetic process
AL497_RS22925	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL497_RS22930	COG0667	Aldo Keto reductase
AL497_RS22955	COG2315	Protein conserved in bacteria
AL497_RS23035	COG2814	Major facilitator Superfamily
AL497_RS23045	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL497_RS23055	COG0765	amino acid transport
AL497_RS23060	COG0765	amino acid transport
AL497_RS23110	COG1953	Uracil, thiamine, allantoin
AL497_RS23115	COG0402	S-adenosylhomocysteine deaminase activity
AL497_RS23120	COG2351	hydroxyisourate hydrolase activity
AL497_RS23130	COG2233	PERMEase
AL497_RS23135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL497_RS23165	COG0454	-acetyltransferase
AL497_RS23170	COG0668	transmembrane transport
AL497_RS23245	COG0515	serine threonine protein kinase
AL497_RS23245	COG2815	serine threonine protein kinase
AL497_RS23360	COG1649	PFAM Uncharacterised BCR, COG1649
AL497_RS23365	COG2070	2-Nitropropane dioxygenase
AL497_RS23370	COG0583	DNA-binding transcription factor activity
AL497_RS23405	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL497_RS23410	COG1116	anion transmembrane transporter activity
AL497_RS23415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL497_RS23420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL497_RS23425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL497_RS23430	COG0076	glutamate decarboxylase activity
AL497_RS23440	COG2205	protein histidine kinase activity
AL497_RS23510	COG0583	DNA-binding transcription factor activity
AL497_RS23520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL497_RS23525	COG1309	transcriptional regulator
AL497_RS23550	COG2814	Major facilitator Superfamily
AL497_RS23560	COG0583	DNA-binding transcription factor activity
AL497_RS23565	COG0583	DNA-binding transcription factor activity
AL497_RS23570	COG0243	molybdopterin cofactor binding
AL497_RS23575	COG1271	oxidase subunit
AL497_RS23580	COG1294	oxidase, subunit
AL497_RS23590	COG3781	membrane
AL497_RS23595	COG2837	iron assimilation
AL497_RS23610	COG1764	response to oxidative stress
AL497_RS23635	COG1609	Transcriptional regulator
AL497_RS23655	COG0488	(ABC) transporter
AL497_RS23665	COG1064	alcohol dehydrogenase
AL497_RS23670	COG0747	negative chemotaxis
AL497_RS23680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL497_RS23690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS23700	COG2814	Major facilitator Superfamily
AL497_RS23760	COG2864	formate dehydrogenase
AL497_RS23765	COG0437	4 iron, 4 sulfur cluster binding
AL497_RS23780	COG0697	spore germination
AL497_RS23795	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL497_RS23805	COG3485	protocatechuate 3,4-dioxygenase
AL497_RS23810	COG4829	muconolactone delta-isomerase
AL497_RS23815	COG4948	Mandelate Racemase Muconate Lactonizing
AL497_RS23825	COG1414	Transcriptional regulator
AL497_RS23845	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL497_RS23850	COG1140	nitrate reductase beta subunit
AL497_RS23855	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL497_RS23860	COG2181	nitrate reductase activity
AL497_RS23865	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AL497_RS23870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL497_RS23895	COG0625	glutathione transferase activity
AL497_RS23900	COG3619	membrane
AL497_RS23905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS23910	COG1126	abc transporter atp-binding protein
AL497_RS23925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL497_RS23930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS23935	COG1473	amidohydrolase
AL497_RS23940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL497_RS23970	COG4772	TonB-dependent receptor
AL497_RS23975	COG3691	Protein conserved in bacteria
AL497_RS23980	COG2130	NADP-dependent
AL497_RS23990	COG1247	-acetyltransferase
AL497_RS23995	COG3238	Protein conserved in bacteria
AL497_RS24005	COG0747	negative chemotaxis
AL497_RS24010	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS24015	COG2267	carboxylic ester hydrolase activity
AL497_RS24035	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS24040	COG1177	transmembrane transport
AL497_RS24050	COG3842	ATPase activity
AL497_RS24055	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL497_RS24060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL497_RS24070	COG1271	oxidase subunit
AL497_RS24075	COG1294	oxidase, subunit
AL497_RS24090	COG0826	peptidase U32
AL497_RS24095	COG1396	sequence-specific DNA binding
AL497_RS24100	COG3135	benzoate transporter
AL497_RS24105	COG3708	Transcriptional regulator
AL497_RS24105	COG2207	Transcriptional regulator
AL497_RS24110	COG0697	spore germination
AL497_RS24120	COG0747	negative chemotaxis
AL497_RS24125	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL497_RS24130	COG0500	methyltransferase
AL497_RS24135	COG1275	C4-dicarboxylate transporter malic acid transport protein
AL497_RS24140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL497_RS24145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL497_RS24165	COG0436	Aminotransferase
AL497_RS24170	COG1823	symporter activity
AL497_RS24175	COG1335	isochorismatase
AL497_RS24180	COG0583	DNA-binding transcription factor activity
AL497_RS24185	COG2272	Belongs to the type-B carboxylesterase lipase family
AL497_RS24190	COG5383	Protein conserved in bacteria
AL497_RS24195	COG3485	protocatechuate 3,4-dioxygenase
AL497_RS24200	COG3485	protocatechuate 3,4-dioxygenase
AL497_RS24205	COG0583	DNA-binding transcription factor activity
AL497_RS24245	COG3038	cytochrome b561
AL497_RS24280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL497_RS24285	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL497_RS24290	COG1113	amino acid transport
AL497_RS24295	COG2988	succinylglutamate desuccinylase activity
AL497_RS24300	COG3724	N-succinylarginine dihydrolase activity
AL497_RS24305	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS24310	COG3138	arginine N-succinyltransferase
AL497_RS24315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL497_RS24320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL497_RS24345	COG4122	O-methyltransferase activity
AL497_RS24350	COG1643	Atp-dependent helicase
AL497_RS24365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL497_RS24370	COG3327	negative regulation of DNA-templated transcription, initiation
AL497_RS24375	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AL497_RS24380	COG0183	Belongs to the thiolase family
AL497_RS24385	COG2050	protein possibly involved in aromatic compounds catabolism
AL497_RS24390	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL497_RS24395	COG1024	Enoyl-CoA hydratase
AL497_RS24400	COG1024	Enoyl-CoA hydratase
AL497_RS24405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL497_RS24410	COG2151	metal-sulfur cluster biosynthetic enzyme
AL497_RS24415	COG3396	Phenylacetate-CoA oxygenase
AL497_RS24420	COG3460	Phenylacetate-CoA oxygenase
AL497_RS24425	COG3396	Phenylacetate-CoA oxygenase
AL497_RS24430	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS24430	COG2030	dehydratase
AL497_RS24445	COG1012	belongs to the aldehyde dehydrogenase family
AL497_RS24450	COG2207	Transcriptional regulator
AL497_RS24455	COG3784	Protein of unknown function (DUF1318)
AL497_RS24465	COG2911	Protein conserved in bacteria
AL497_RS24470	COG0586	Pfam SNARE associated Golgi protein
AL497_RS24475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL497_RS24480	COG3187	Heat shock protein
AL497_RS24485	COG3042	response to heat
AL497_RS24490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AL497_RS24490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL497_RS24490	COG1013	pyruvate-flavodoxin oxidoreductase activity
AL497_RS24490	COG0674	pyruvate-flavodoxin oxidoreductase activity
AL497_RS24495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL497_RS24500	COG0589	response to stress
AL497_RS24510	COG0513	Belongs to the DEAD box helicase family
AL497_RS24530	COG1940	carbohydrate kinase activity
AL497_RS24535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL497_RS24560	COG4172	Belongs to the ABC transporter superfamily
AL497_RS24565	COG1349	DNA-binding transcription factor activity
AL497_RS24570	COG0673	inositol 2-dehydrogenase activity
AL497_RS24580	COG0693	protein deglycase activity
AL497_RS24620	COG4580	involved in the transport of maltose and maltodextrins
AL497_RS24625	COG2211	Major facilitator Superfamily
AL497_RS24630	COG3507	Belongs to the glycosyl hydrolase 43 family
AL497_RS24635	COG0656	L-ascorbic acid biosynthetic process
AL497_RS24650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL497_RS24660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL497_RS24675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL497_RS24685	COG4166	transmembrane transport
AL497_RS24690	COG2866	Carboxypeptidase
AL497_RS24695	COG4948	Mandelate Racemase Muconate Lactonizing
AL497_RS24700	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AL497_RS24705	COG3180	Ammonia monooxygenase
AL497_RS24720	COG3106	COG3106 Predicted ATPase
AL497_RS24730	COG1983	PspC domain protein
AL497_RS24740	COG1842	Phage shock protein A
AL497_RS24745	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL497_RS24755	COG1473	amidohydrolase
AL497_RS24780	COG2135	peptidase activity
AL497_RS24785	COG2200	EAL domain
AL497_RS24790	COG0431	NADPH-dependent FMN reductase
AL497_RS24795	COG0640	Transcriptional regulator
AL497_RS24810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL497_RS24860	COG1196	nuclear chromosome segregation
AL497_RS24860	COG1196	nuclear chromosome segregation
AL497_RS24940	COG3728	DNA packaging
AL497_RS24940	COG5484	DNA packaging
AL497_RS25005	COG0484	heat shock protein binding
AL497_RS25035	COG0456	acetyltransferase
AL497_RS25075	COG1846	Transcriptional regulator
AL497_RS25125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL497_RS25160	COG4171	peptide transport system, permease
AL497_RS25170	COG4172	Belongs to the ABC transporter superfamily
AL497_RS25175	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL497_RS25185	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL497_RS25190	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL497_RS25190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL497_RS25205	COG1349	DNA-binding transcription factor activity
AL497_RS25215	COG0023	Translation Initiation Factor
AL497_RS25225	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL497_RS25230	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL497_RS25235	COG0671	phosphoesterase, PA-phosphatase related
AL497_RS25245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL497_RS25280	COG0616	signal peptide processing
AL497_RS25285	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS25290	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AL497_RS25295	COG2207	Transcriptional regulator
AL497_RS25300	COG1472	Belongs to the glycosyl hydrolase 3 family
AL497_RS25305	COG2211	Major facilitator Superfamily
AL497_RS25315	COG5001	Diguanylate cyclase
AL497_RS25315	COG1716	ATPase activity
AL497_RS25320	COG5001	Diguanylate cyclase
AL497_RS25320	COG1716	ATPase activity
AL497_RS25325	COG0009	L-threonylcarbamoyladenylate synthase
AL497_RS25335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL497_RS25340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL497_RS25340	COG0512	Glutamine amidotransferase of anthranilate synthase
AL497_RS25345	COG0134	indole-3-glycerol-phosphate synthase activity
AL497_RS25345	COG0135	phosphoribosylanthranilate isomerase activity
AL497_RS25370	COG1566	PFAM secretion protein HlyD family protein
AL497_RS25385	COG0583	DNA-binding transcription factor activity
AL497_RS25390	COG3047	cAMP biosynthetic process
AL497_RS25395	COG0727	PFAM Uncharacterised protein family (UPF0153)
AL497_RS25420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL497_RS25425	COG1988	membrane-bound metal-dependent
AL497_RS25430	COG1823	symporter activity
AL497_RS25440	COG0753	catalase activity
AL497_RS25450	COG1486	melibiose metabolic process
AL497_RS25455	COG2169	Transcriptional regulator
AL497_RS25455	COG1917	Cupin 2, conserved barrel domain protein
AL497_RS25460	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL497_RS25465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS25470	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL497_RS25475	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL497_RS25485	COG0322	excinuclease ABC activity
AL497_RS25490	COG3678	ATP-independent chaperone mediated protein folding
AL497_RS25510	COG3138	arginine N-succinyltransferase
AL497_RS25525	COG0708	Exodeoxyribonuclease III
AL497_RS25530	COG0398	Pfam SNARE associated Golgi protein
AL497_RS25535	COG0398	Pfam SNARE associated Golgi protein
AL497_RS25540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL497_RS25545	COG4134	Bacterial extracellular solute-binding protein
AL497_RS25550	COG4135	transport system, permease component
AL497_RS25555	COG4136	ATPase activity
AL497_RS25560	COG2897	thiosulfate sulfurtransferase activity
AL497_RS25565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL497_RS25570	COG0494	nUDIX hydrolase
AL497_RS25580	COG1028	Short-chain dehydrogenase reductase Sdr
AL497_RS25580	COG0604	alcohol dehydrogenase
AL497_RS25580	COG3321	synthase
AL497_RS25590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL497_RS25595	COG0709	Synthesizes selenophosphate from selenide and ATP
AL497_RS25605	COG0778	Nitroreductase
AL497_RS25610	COG0616	signal peptide processing
AL497_RS25615	COG0252	asparaginase activity
AL497_RS25620	COG1335	isochorismatase
AL497_RS25630	COG3139	Protein of unknown function (DUF1315)
AL497_RS25650	COG3713	MltA-interacting MipA family protein
AL497_RS25655	COG2766	serine protein kinase
AL497_RS25670	COG2199	diguanylate cyclase activity
AL497_RS25675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL497_RS25685	COG2207	Transcriptional regulator
AL497_RS25690	COG2807	transmembrane transport
AL497_RS25695	COG0504	CTP synthase activity
AL497_RS25700	COG3189	MarR family transcriptional regulator
AL497_RS25705	COG3042	response to heat
AL497_RS25710	COG2199	diguanylate cyclase activity
AL497_RS25710	COG2203	Gaf domain
AL497_RS25730	COG3182	Iron-regulated membrane protein
AL497_RS25740	COG1560	Kdo2-lipid A biosynthetic process
AL497_RS25745	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL497_RS25750	COG3706	GGDEF domain
AL497_RS25780	COG3209	COG3209 Rhs family protein
AL497_RS25795	COG3209	COG3209 Rhs family protein
AL497_RS25820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL497_RS25915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL497_RS25925	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL497_RS25945	COG1760	l-serine dehydratase
AL497_RS25950	COG1882	Formate acetyltransferase
AL497_RS25970	COG0583	DNA-binding transcription factor activity
AL497_RS25975	COG2814	Major facilitator Superfamily
AL497_RS25990	COG4774	siderophore transport
AL497_RS26000	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL497_RS26020	COG2719	SpoVR family
AL497_RS26050	COG2755	lipolytic protein G-D-S-L family
AL497_RS26050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL497_RS26065	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL497_RS26080	COG2894	cell division
AL497_RS26090	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides