locus-tag	class	description
F6O44_RS00010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F6O44_RS00015	COG1215	transferase activity, transferring glycosyl groups
F6O44_RS00020	COG5039	Polysaccharide pyruvyl transferase
F6O44_RS00160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F6O44_RS00175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F6O44_RS00190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F6O44_RS00205	COG0531	amino acid
F6O44_RS00210	COG0640	Transcriptional regulator
F6O44_RS00215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F6O44_RS00220	COG2925	Exonuclease
F6O44_RS00225	COG1686	Belongs to the peptidase S11 family
F6O44_RS00235	COG1289	transmembrane transporter activity
F6O44_RS00260	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F6O44_RS00270	COG2814	Major facilitator Superfamily
F6O44_RS00275	COG0673	inositol 2-dehydrogenase activity
F6O44_RS00280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS00280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS00285	COG1082	Xylose isomerase domain protein TIM barrel
F6O44_RS00290	COG1609	Transcriptional regulator
F6O44_RS00295	COG0095	Lipoate-protein ligase
F6O44_RS00300	COG0477	Major facilitator Superfamily
F6O44_RS00310	COG3300	MHYT domain
F6O44_RS00310	COG5001	Diguanylate cyclase
F6O44_RS00315	COG3615	Tellurite resistance protein tehB
F6O44_RS00345	COG0534	Mate efflux family protein
F6O44_RS00355	COG1725	Transcriptional regulator
F6O44_RS00385	COG1181	Belongs to the D-alanine--D-alanine ligase family
F6O44_RS00390	COG0477	Major facilitator Superfamily
F6O44_RS00395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F6O44_RS00415	COG2977	Belongs to the P-Pant transferase superfamily
F6O44_RS00435	COG1376	ErfK ybiS ycfS ynhG family protein
F6O44_RS00465	COG0463	Glycosyl transferase, family 2
F6O44_RS00470	COG2246	polysaccharide biosynthetic process
F6O44_RS00475	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F6O44_RS00485	COG1418	mRNA catabolic process
F6O44_RS00490	COG0270	DNA (cytosine-5-)-methyltransferase activity
F6O44_RS00495	COG3727	T/G mismatch-specific endonuclease activity
F6O44_RS00500	COG0697	spore germination
F6O44_RS00505	COG2354	Protein conserved in bacteria
F6O44_RS00510	COG5475	Uncharacterized small protein (DUF2158)
F6O44_RS00540	COG0366	Alpha amylase catalytic
F6O44_RS00545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6O44_RS00555	COG0765	amino acid transport
F6O44_RS00560	COG1126	abc transporter atp-binding protein
F6O44_RS00565	COG2197	response regulator
F6O44_RS00575	COG2197	response regulator
F6O44_RS00605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F6O44_RS00610	COG3152	Membrane
F6O44_RS00615	COG3012	SEC-C Motif Domain Protein
F6O44_RS00615	COG3318	Belongs to the UPF0149 family
F6O44_RS00620	COG0814	amino acid
F6O44_RS00630	COG1528	Iron-storage protein
F6O44_RS00640	COG0477	Major facilitator Superfamily
F6O44_RS00650	COG1528	Iron-storage protein
F6O44_RS00655	COG1879	ABC-type sugar transport system periplasmic component
F6O44_RS00665	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6O44_RS00695	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F6O44_RS00705	COG3102	Protein conserved in bacteria
F6O44_RS00725	COG3788	relative of glutathione S-transferase, MAPEG superfamily
F6O44_RS00730	COG1801	Protein of unknown function DUF72
F6O44_RS00735	COG1335	isochorismatase
F6O44_RS00745	COG0494	nUDIX hydrolase
F6O44_RS00770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F6O44_RS00780	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
F6O44_RS00785	COG0739	heme binding
F6O44_RS00790	COG1560	Kdo2-lipid A biosynthetic process
F6O44_RS00800	COG1737	Transcriptional regulator
F6O44_RS00810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F6O44_RS00815	COG0129	dihydroxy-acid dehydratase activity
F6O44_RS00820	COG0800	Aldolase
F6O44_RS00830	COG3141	response to X-ray
F6O44_RS00835	COG2979	Protein of unknown function (DUF533)
F6O44_RS00840	COG1770	oligopeptidase
F6O44_RS00845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F6O44_RS00855	COG2372	response to copper ion
F6O44_RS00860	COG1276	copper resistance
F6O44_RS00900	COG2990	Protein conserved in bacteria
F6O44_RS00925	COG3008	intermembrane lipid transfer
F6O44_RS00930	COG2995	paraquat-inducible protein a
F6O44_RS00935	COG1956	GAF domain-containing protein
F6O44_RS00955	COG2814	Major facilitator Superfamily
F6O44_RS00960	COG1414	Transcriptional regulator
F6O44_RS00990	COG0768	penicillin binding
F6O44_RS00995	COG2226	methyltransferase
F6O44_RS01010	COG3716	PTS system mannose fructose sorbose family IID component
F6O44_RS01015	COG3715	PTS system
F6O44_RS01020	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6O44_RS01020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS01025	COG1253	flavin adenine dinucleotide binding
F6O44_RS01035	COG1760	l-serine dehydratase
F6O44_RS01055	COG0251	oxidation-reduction process
F6O44_RS01060	COG1199	ATP-dependent helicase activity
F6O44_RS01070	COG3065	identical protein binding
F6O44_RS01080	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F6O44_RS01090	COG2894	cell division
F6O44_RS01105	COG0179	Fumarylacetoacetate (FAA) hydrolase
F6O44_RS01145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F6O44_RS01155	COG2135	peptidase activity
F6O44_RS01180	COG2719	SpoVR family
F6O44_RS01200	COG1619	proteins homologs of microcin C7 resistance protein MccF
F6O44_RS01210	COG4774	siderophore transport
F6O44_RS01225	COG2814	Major facilitator Superfamily
F6O44_RS01230	COG0583	DNA-binding transcription factor activity
F6O44_RS01245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F6O44_RS01250	COG1882	Formate acetyltransferase
F6O44_RS01255	COG1760	l-serine dehydratase
F6O44_RS01275	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F6O44_RS01285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6O44_RS01390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F6O44_RS01415	COG3209	COG3209 Rhs family protein
F6O44_RS01425	COG3209	COG3209 Rhs family protein
F6O44_RS01440	COG3300	MHYT domain
F6O44_RS01440	COG5001	Diguanylate cyclase
F6O44_RS01460	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
F6O44_RS01465	COG1560	Kdo2-lipid A biosynthetic process
F6O44_RS01475	COG3182	Iron-regulated membrane protein
F6O44_RS01495	COG2199	diguanylate cyclase activity
F6O44_RS01495	COG2203	Gaf domain
F6O44_RS01500	COG4974	Belongs to the 'phage' integrase family
F6O44_RS01550	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F6O44_RS01585	COG4695	Portal protein
F6O44_RS01725	COG3042	response to heat
F6O44_RS01730	COG3189	MarR family transcriptional regulator
F6O44_RS01735	COG0504	CTP synthase activity
F6O44_RS01740	COG2807	transmembrane transport
F6O44_RS01745	COG2207	Transcriptional regulator
F6O44_RS01755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F6O44_RS01760	COG2199	diguanylate cyclase activity
F6O44_RS01775	COG2766	serine protein kinase
F6O44_RS01780	COG3713	MltA-interacting MipA family protein
F6O44_RS01800	COG3139	Protein of unknown function (DUF1315)
F6O44_RS01810	COG1335	isochorismatase
F6O44_RS01815	COG0252	asparaginase activity
F6O44_RS01820	COG0616	signal peptide processing
F6O44_RS01825	COG0778	Nitroreductase
F6O44_RS01835	COG0709	Synthesizes selenophosphate from selenide and ATP
F6O44_RS01840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F6O44_RS01850	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS01850	COG0604	alcohol dehydrogenase
F6O44_RS01850	COG3321	synthase
F6O44_RS01860	COG0494	nUDIX hydrolase
F6O44_RS01865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F6O44_RS01870	COG2897	thiosulfate sulfurtransferase activity
F6O44_RS01875	COG4136	ATPase activity
F6O44_RS01880	COG4135	transport system, permease component
F6O44_RS01885	COG4134	Bacterial extracellular solute-binding protein
F6O44_RS01890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F6O44_RS01895	COG0398	Pfam SNARE associated Golgi protein
F6O44_RS01900	COG0398	Pfam SNARE associated Golgi protein
F6O44_RS01905	COG0708	Exodeoxyribonuclease III
F6O44_RS01915	COG3138	arginine N-succinyltransferase
F6O44_RS01930	COG3678	ATP-independent chaperone mediated protein folding
F6O44_RS01935	COG0322	excinuclease ABC activity
F6O44_RS01945	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F6O44_RS01950	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6O44_RS01955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6O44_RS01960	COG1447	Phosphotransferase system cellobiose-specific component IIA
F6O44_RS01965	COG2169	Transcriptional regulator
F6O44_RS01965	COG1917	Cupin 2, conserved barrel domain protein
F6O44_RS01970	COG1486	melibiose metabolic process
F6O44_RS01980	COG0753	catalase activity
F6O44_RS01990	COG1823	symporter activity
F6O44_RS01995	COG1988	membrane-bound metal-dependent
F6O44_RS02000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F6O44_RS02025	COG0727	PFAM Uncharacterised protein family (UPF0153)
F6O44_RS02030	COG3047	cAMP biosynthetic process
F6O44_RS02035	COG0583	DNA-binding transcription factor activity
F6O44_RS02050	COG1566	PFAM secretion protein HlyD family protein
F6O44_RS02080	COG0512	Glutamine amidotransferase of anthranilate synthase
F6O44_RS02080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F6O44_RS02085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F6O44_RS02095	COG0009	L-threonylcarbamoyladenylate synthase
F6O44_RS02100	COG1716	ATPase activity
F6O44_RS02100	COG5001	Diguanylate cyclase
F6O44_RS02105	COG1716	ATPase activity
F6O44_RS02105	COG5001	Diguanylate cyclase
F6O44_RS02115	COG2211	Major facilitator Superfamily
F6O44_RS02120	COG1472	Belongs to the glycosyl hydrolase 3 family
F6O44_RS02125	COG2207	Transcriptional regulator
F6O44_RS02130	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
F6O44_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS02165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F6O44_RS02175	COG0671	phosphoesterase, PA-phosphatase related
F6O44_RS02180	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
F6O44_RS02185	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F6O44_RS02195	COG0023	Translation Initiation Factor
F6O44_RS02205	COG1349	DNA-binding transcription factor activity
F6O44_RS02220	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F6O44_RS02220	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F6O44_RS02225	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F6O44_RS02235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F6O44_RS02240	COG4172	Belongs to the ABC transporter superfamily
F6O44_RS02250	COG4171	peptide transport system, permease
F6O44_RS02275	COG1473	amidohydrolase
F6O44_RS02285	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F6O44_RS02290	COG1842	Phage shock protein A
F6O44_RS02300	COG1983	PspC domain protein
F6O44_RS02310	COG3106	COG3106 Predicted ATPase
F6O44_RS02325	COG3180	Ammonia monooxygenase
F6O44_RS02330	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F6O44_RS02335	COG4948	Mandelate Racemase Muconate Lactonizing
F6O44_RS02340	COG2866	Carboxypeptidase
F6O44_RS02345	COG4166	transmembrane transport
F6O44_RS02355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS02370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F6O44_RS02380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6O44_RS02395	COG0656	L-ascorbic acid biosynthetic process
F6O44_RS02400	COG3507	Belongs to the glycosyl hydrolase 43 family
F6O44_RS02405	COG2211	Major facilitator Superfamily
F6O44_RS02410	COG4580	involved in the transport of maltose and maltodextrins
F6O44_RS02485	COG0693	protein deglycase activity
F6O44_RS02495	COG0673	inositol 2-dehydrogenase activity
F6O44_RS02500	COG1349	DNA-binding transcription factor activity
F6O44_RS02505	COG4172	Belongs to the ABC transporter superfamily
F6O44_RS02530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6O44_RS02535	COG1940	carbohydrate kinase activity
F6O44_RS02540	COG0456	acetyltransferase
F6O44_RS02550	COG0513	Belongs to the DEAD box helicase family
F6O44_RS02565	COG3093	addiction module antidote protein HigA
F6O44_RS02570	COG3549	Plasmid maintenance system killer
F6O44_RS02575	COG0589	response to stress
F6O44_RS02580	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F6O44_RS02590	COG3042	response to heat
F6O44_RS02595	COG3187	Heat shock protein
F6O44_RS02600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F6O44_RS02605	COG0586	Pfam SNARE associated Golgi protein
F6O44_RS02610	COG2911	Protein conserved in bacteria
F6O44_RS02620	COG3784	Protein of unknown function (DUF1318)
F6O44_RS02625	COG2207	Transcriptional regulator
F6O44_RS02630	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS02650	COG3396	Phenylacetate-CoA oxygenase
F6O44_RS02655	COG3460	Phenylacetate-CoA oxygenase
F6O44_RS02660	COG3396	Phenylacetate-CoA oxygenase
F6O44_RS02665	COG2151	metal-sulfur cluster biosynthetic enzyme
F6O44_RS02670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F6O44_RS02675	COG1024	Enoyl-CoA hydratase
F6O44_RS02680	COG1024	Enoyl-CoA hydratase
F6O44_RS02685	COG1250	3-hydroxyacyl-CoA dehydrogenase
F6O44_RS02690	COG2050	protein possibly involved in aromatic compounds catabolism
F6O44_RS02695	COG0183	Belongs to the thiolase family
F6O44_RS02700	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
F6O44_RS02705	COG3327	negative regulation of DNA-templated transcription, initiation
F6O44_RS02710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F6O44_RS02725	COG1643	Atp-dependent helicase
F6O44_RS02730	COG4122	O-methyltransferase activity
F6O44_RS02755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F6O44_RS02760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F6O44_RS02765	COG3138	arginine N-succinyltransferase
F6O44_RS02770	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS02775	COG3724	N-succinylarginine dihydrolase activity
F6O44_RS02780	COG2988	succinylglutamate desuccinylase activity
F6O44_RS02785	COG1113	amino acid transport
F6O44_RS02790	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F6O44_RS02795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F6O44_RS02830	COG3038	cytochrome b561
F6O44_RS02870	COG0583	DNA-binding transcription factor activity
F6O44_RS02875	COG3485	protocatechuate 3,4-dioxygenase
F6O44_RS02880	COG3485	protocatechuate 3,4-dioxygenase
F6O44_RS02885	COG5383	Protein conserved in bacteria
F6O44_RS02890	COG2272	Belongs to the type-B carboxylesterase lipase family
F6O44_RS02895	COG0583	DNA-binding transcription factor activity
F6O44_RS02900	COG1335	isochorismatase
F6O44_RS02905	COG1823	symporter activity
F6O44_RS02910	COG0436	Aminotransferase
F6O44_RS02930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F6O44_RS02935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F6O44_RS02940	COG1275	C4-dicarboxylate transporter malic acid transport protein
F6O44_RS02945	COG0500	methyltransferase
F6O44_RS02950	COG2195	Cleaves the N-terminal amino acid of tripeptides
F6O44_RS02955	COG0747	negative chemotaxis
F6O44_RS02965	COG0697	spore germination
F6O44_RS02970	COG2207	Transcriptional regulator
F6O44_RS02970	COG3708	Transcriptional regulator
F6O44_RS02975	COG3135	benzoate transporter
F6O44_RS02980	COG1396	sequence-specific DNA binding
F6O44_RS02985	COG0826	peptidase U32
F6O44_RS03000	COG1294	oxidase, subunit
F6O44_RS03005	COG1271	oxidase subunit
F6O44_RS03010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F6O44_RS03015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F6O44_RS03020	COG3842	ATPase activity
F6O44_RS03025	COG1176	ABC-type spermidine putrescine transport system, permease component I
F6O44_RS03030	COG1177	transmembrane transport
F6O44_RS03035	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS03060	COG2267	carboxylic ester hydrolase activity
F6O44_RS03065	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS03075	COG0747	negative chemotaxis
F6O44_RS03085	COG3238	Protein conserved in bacteria
F6O44_RS03090	COG1247	-acetyltransferase
F6O44_RS03100	COG2130	NADP-dependent
F6O44_RS03105	COG3691	Protein conserved in bacteria
F6O44_RS03110	COG4772	TonB-dependent receptor
F6O44_RS03135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6O44_RS03140	COG1473	amidohydrolase
F6O44_RS03145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6O44_RS03150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6O44_RS03165	COG1126	abc transporter atp-binding protein
F6O44_RS03170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6O44_RS03175	COG3619	membrane
F6O44_RS03180	COG0625	glutathione transferase activity
F6O44_RS03205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F6O44_RS03210	COG2162	N-hydroxyarylamine O-acetyltransferase activity
F6O44_RS03215	COG2181	nitrate reductase activity
F6O44_RS03220	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F6O44_RS03225	COG1140	nitrate reductase beta subunit
F6O44_RS03230	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F6O44_RS03250	COG1414	Transcriptional regulator
F6O44_RS03255	COG4948	Mandelate Racemase Muconate Lactonizing
F6O44_RS03260	COG4829	muconolactone delta-isomerase
F6O44_RS03265	COG3485	protocatechuate 3,4-dioxygenase
F6O44_RS03275	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F6O44_RS03290	COG0697	spore germination
F6O44_RS03300	COG0437	4 iron, 4 sulfur cluster binding
F6O44_RS03305	COG2864	formate dehydrogenase
F6O44_RS03365	COG2814	Major facilitator Superfamily
F6O44_RS03385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6O44_RS03395	COG0747	negative chemotaxis
F6O44_RS03400	COG1064	alcohol dehydrogenase
F6O44_RS03410	COG0488	(ABC) transporter
F6O44_RS03430	COG1609	Transcriptional regulator
F6O44_RS03455	COG1764	response to oxidative stress
F6O44_RS03470	COG2837	iron assimilation
F6O44_RS03475	COG3781	membrane
F6O44_RS03485	COG1294	oxidase, subunit
F6O44_RS03490	COG1271	oxidase subunit
F6O44_RS03495	COG0243	molybdopterin cofactor binding
F6O44_RS03500	COG0583	DNA-binding transcription factor activity
F6O44_RS03505	COG0583	DNA-binding transcription factor activity
F6O44_RS03515	COG2814	Major facilitator Superfamily
F6O44_RS03540	COG1309	transcriptional regulator
F6O44_RS03545	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F6O44_RS03555	COG0583	DNA-binding transcription factor activity
F6O44_RS03625	COG2205	protein histidine kinase activity
F6O44_RS03635	COG0076	glutamate decarboxylase activity
F6O44_RS03640	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F6O44_RS03645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F6O44_RS03650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F6O44_RS03655	COG1116	anion transmembrane transporter activity
F6O44_RS03660	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F6O44_RS03700	COG2070	2-Nitropropane dioxygenase
F6O44_RS03835	COG2815	serine threonine protein kinase
F6O44_RS03835	COG0515	serine threonine protein kinase
F6O44_RS03940	COG0668	transmembrane transport
F6O44_RS03945	COG0454	-acetyltransferase
F6O44_RS03975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F6O44_RS03980	COG2233	PERMEase
F6O44_RS03990	COG2351	hydroxyisourate hydrolase activity
F6O44_RS03995	COG0402	S-adenosylhomocysteine deaminase activity
F6O44_RS04000	COG1953	Uracil, thiamine, allantoin
F6O44_RS04055	COG0765	amino acid transport
F6O44_RS04060	COG0765	amino acid transport
F6O44_RS04070	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F6O44_RS04080	COG2814	Major facilitator Superfamily
F6O44_RS04085	COG0583	DNA-binding transcription factor activity
F6O44_RS04130	COG2801	Transposase and inactivated derivatives
F6O44_RS04135	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F6O44_RS04135	COG0456	acetyltransferase
F6O44_RS04150	COG0588	phosphoglycerate mutase activity
F6O44_RS04155	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F6O44_RS04165	COG4191	Histidine kinase
F6O44_RS04180	COG2814	Major facilitator Superfamily
F6O44_RS04205	COG0401	homolog of Blt101
F6O44_RS04210	COG1312	Catalyzes the dehydration of D-mannonate
F6O44_RS04215	COG2610	gluconate transmembrane transporter activity
F6O44_RS04245	COG3111	PFAM Bacterial OB fold (BOF) protein
F6O44_RS04255	COG2323	membrane
F6O44_RS04270	COG0366	Alpha amylase catalytic
F6O44_RS04280	COG3685	Protein conserved in bacteria
F6O44_RS04290	COG3685	Protein conserved in bacteria
F6O44_RS04295	COG3729	General stress protein
F6O44_RS04300	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS04325	COG2207	Transcriptional regulator
F6O44_RS04330	COG4628	conserved protein (DUF2132)
F6O44_RS04350	COG2011	ABC-type metal ion transport system permease component
F6O44_RS04355	COG2070	2-Nitropropane dioxygenase
F6O44_RS04365	COG0477	Major facilitator Superfamily
F6O44_RS04370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F6O44_RS04375	COG0697	spore germination
F6O44_RS04405	COG1349	DNA-binding transcription factor activity
F6O44_RS04410	COG3395	kinase activity
F6O44_RS04415	COG0235	Class ii aldolase
F6O44_RS04420	COG3622	Belongs to the hyi family
F6O44_RS04425	COG2271	Major facilitator Superfamily
F6O44_RS04430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F6O44_RS04455	COG2199	diguanylate cyclase activity
F6O44_RS04470	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS04475	COG0583	DNA-binding transcription factor activity
F6O44_RS04480	COG1349	DNA-binding transcription factor activity
F6O44_RS04485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F6O44_RS04490	COG3395	kinase activity
F6O44_RS04500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F6O44_RS04520	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS04540	COG1846	Transcriptional regulator
F6O44_RS04555	COG0697	spore germination
F6O44_RS04560	COG2814	Major facilitator Superfamily
F6O44_RS04570	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F6O44_RS04595	COG0583	DNA-binding transcription factor activity
F6O44_RS04605	COG2203	Gaf domain
F6O44_RS04605	COG2199	diguanylate cyclase activity
F6O44_RS04625	COG2223	nitrite transmembrane transporter activity
F6O44_RS04630	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F6O44_RS04640	COG0339	signal peptide processing
F6O44_RS04645	COG4221	oxidoreductase activity
F6O44_RS04650	COG1802	Transcriptional regulator
F6O44_RS04660	COG0246	Mannitol dehydrogenase
F6O44_RS04665	COG0477	Major facilitator Superfamily
F6O44_RS04670	COG1063	alcohol dehydrogenase
F6O44_RS04675	COG4948	Mandelate Racemase Muconate Lactonizing
F6O44_RS04680	COG2271	Major facilitator Superfamily
F6O44_RS04695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F6O44_RS04710	COG0243	molybdopterin cofactor binding
F6O44_RS04715	COG0437	4 iron, 4 sulfur cluster binding
F6O44_RS04720	COG3302	dmso reductase anchor subunit
F6O44_RS04735	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F6O44_RS04740	COG1940	carbohydrate kinase activity
F6O44_RS04745	COG0583	DNA-binding transcription factor activity
F6O44_RS04750	COG2814	Major facilitator Superfamily
F6O44_RS04755	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
F6O44_RS04775	COG3591	Belongs to the peptidase S1B family
F6O44_RS04780	COG3300	MHYT domain
F6O44_RS04780	COG5001	Diguanylate cyclase
F6O44_RS04800	COG0628	permease
F6O44_RS04830	COG0679	Auxin Efflux Carrier
F6O44_RS04840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F6O44_RS04855	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F6O44_RS04860	COG3290	protein histidine kinase activity
F6O44_RS04865	COG4565	transcriptional regulatory protein
F6O44_RS04890	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F6O44_RS04890	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F6O44_RS04900	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F6O44_RS04905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F6O44_RS04915	COG0183	Belongs to the thiolase family
F6O44_RS04920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F6O44_RS04930	COG1414	Transcriptional regulator
F6O44_RS04935	COG2840	Smr protein MutS2
F6O44_RS04940	COG0583	DNA-binding transcription factor activity
F6O44_RS04950	COG1473	amidohydrolase
F6O44_RS04955	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
F6O44_RS04970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F6O44_RS04975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F6O44_RS04990	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F6O44_RS04995	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F6O44_RS05015	COG0531	amino acid
F6O44_RS05025	COG3136	membrane protein required for alginate biosynthesis
F6O44_RS05030	COG0745	RESPONSE REGULATOR receiver
F6O44_RS05040	COG2205	protein histidine kinase activity
F6O44_RS05060	COG1482	cell wall glycoprotein biosynthetic process
F6O44_RS05065	COG5339	Protein conserved in bacteria
F6O44_RS05070	COG1609	Transcriptional regulator
F6O44_RS05075	COG1263	PTS System
F6O44_RS05075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6O44_RS05080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F6O44_RS05090	COG2391	methyltransferase activity
F6O44_RS05095	COG0425	Belongs to the sulfur carrier protein TusA family
F6O44_RS05115	COG5562	phage envelope protein
F6O44_RS05125	COG0673	inositol 2-dehydrogenase activity
F6O44_RS05135	COG2723	6-phospho-beta-galactosidase activity
F6O44_RS05170	COG4659	FMN binding
F6O44_RS05180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F6O44_RS05195	COG0625	glutathione transferase activity
F6O44_RS05200	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
F6O44_RS05215	COG3895	Periplasmic Protein
F6O44_RS05230	COG3706	GGDEF domain
F6O44_RS05245	COG1566	PFAM secretion protein HlyD family protein
F6O44_RS05250	COG1289	transmembrane transporter activity
F6O44_RS05255	COG2032	superoxide dismutase activity
F6O44_RS05260	COG4989	oxidoreductase activity
F6O44_RS05265	COG3313	Fe-S protein
F6O44_RS05270	COG1309	transcriptional regulator
F6O44_RS05275	COG1902	pentaerythritol trinitrate reductase activity
F6O44_RS05280	COG0346	lactoylglutathione lyase activity
F6O44_RS05290	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F6O44_RS05300	COG2207	Transcriptional regulator
F6O44_RS05300	COG3708	Transcriptional regulator
F6O44_RS05305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F6O44_RS05310	COG2814	Major facilitator Superfamily
F6O44_RS05325	COG0583	DNA-binding transcription factor activity
F6O44_RS05330	COG2814	Major facilitator Superfamily
F6O44_RS05335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F6O44_RS05340	COG0307	riboflavin synthase, alpha
F6O44_RS05345	COG0534	Mate efflux family protein
F6O44_RS05405	COG2223	nitrite transmembrane transporter activity
F6O44_RS05415	COG3829	transcription factor binding
F6O44_RS05420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F6O44_RS05425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F6O44_RS05430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F6O44_RS05440	COG0549	Belongs to the carbamate kinase family
F6O44_RS05445	COG3608	succinylglutamate desuccinylase aspartoacylase
F6O44_RS05445	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F6O44_RS05450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F6O44_RS05455	COG2068	MobA-Related Protein
F6O44_RS05460	COG0493	'glutamate synthase
F6O44_RS05460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6O44_RS05465	COG0402	S-adenosylhomocysteine deaminase activity
F6O44_RS05470	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6O44_RS05475	COG0493	'glutamate synthase
F6O44_RS05475	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6O44_RS05480	COG2233	PERMEase
F6O44_RS05510	COG1349	DNA-binding transcription factor activity
F6O44_RS05515	COG0346	lactoylglutathione lyase activity
F6O44_RS05540	COG0444	Belongs to the ABC transporter superfamily
F6O44_RS05545	COG4608	Belongs to the ABC transporter superfamily
F6O44_RS05555	COG4993	Dehydrogenase
F6O44_RS05570	COG0583	DNA-binding transcription factor activity
F6O44_RS05580	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F6O44_RS05590	COG1250	3-hydroxyacyl-CoA dehydrogenase
F6O44_RS05595	COG2610	gluconate transmembrane transporter activity
F6O44_RS05600	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS05635	COG1138	Cytochrome C-type biogenesis protein
F6O44_RS05665	COG1175	transmembrane transport
F6O44_RS05680	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F6O44_RS05705	COG0456	acetyltransferase
F6O44_RS05710	COG1396	sequence-specific DNA binding
F6O44_RS05725	COG0583	DNA-binding transcription factor activity
F6O44_RS05740	COG0113	porphobilinogen synthase activity
F6O44_RS05745	COG0697	spore germination
F6O44_RS05770	COG1280	lysine exporter protein (LysE YggA)
F6O44_RS05790	COG2378	regulation of single-species biofilm formation
F6O44_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS05820	COG1683	Conserved Protein
F6O44_RS05825	COG1473	amidohydrolase
F6O44_RS05835	COG1126	abc transporter atp-binding protein
F6O44_RS05840	COG0765	amino acid transport
F6O44_RS05860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6O44_RS05865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6O44_RS05870	COG1120	ATPase activity
F6O44_RS05875	COG4774	siderophore transport
F6O44_RS05880	COG1116	anion transmembrane transporter activity
F6O44_RS05905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6O44_RS05910	COG0583	DNA-binding transcription factor activity
F6O44_RS05935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F6O44_RS05940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6O44_RS05945	COG1120	ATPase activity
F6O44_RS05955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F6O44_RS05960	COG2271	Major facilitator Superfamily
F6O44_RS05965	COG3185	4-Hydroxyphenylpyruvate dioxygenase
F6O44_RS05965	COG1082	Xylose isomerase domain protein TIM barrel
F6O44_RS05995	COG1376	ErfK ybiS ycfS ynhG family protein
F6O44_RS06010	COG0719	Fe-S assembly protein
F6O44_RS06015	COG0396	ATPase activity
F6O44_RS06020	COG0719	Fe-S assembly protein
F6O44_RS06025	COG0316	Belongs to the HesB IscA family
F6O44_RS06050	COG2261	transglycosylase associated protein
F6O44_RS06055	COG3422	double-strand break repair
F6O44_RS06060	COG2050	protein possibly involved in aromatic compounds catabolism
F6O44_RS06075	COG0628	permease
F6O44_RS06085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F6O44_RS06085	COG0574	Belongs to the PEP-utilizing enzyme family
F6O44_RS06100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F6O44_RS06105	COG4256	Hemin uptake protein
F6O44_RS06115	COG0791	NLP P60 protein
F6O44_RS06125	COG0386	Belongs to the glutathione peroxidase family
F6O44_RS06145	COG0583	DNA-binding transcription factor activity
F6O44_RS06165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F6O44_RS06165	COG0072	phenylalanine-tRNA ligase activity
F6O44_RS06180	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F6O44_RS06200	COG2135	peptidase activity
F6O44_RS06240	COG3137	Salt-induced outer membrane protein
F6O44_RS06245	COG1105	Belongs to the carbohydrate kinase PfkB family
F6O44_RS06255	COG3001	Fructosamine kinase
F6O44_RS06260	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
F6O44_RS06265	COG2350	Protein conserved in bacteria
F6O44_RS06300	COG0823	Involved in the tonB-independent uptake of proteins
F6O44_RS06305	COG1917	Cupin 2, conserved barrel domain protein
F6O44_RS06330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F6O44_RS06340	COG0444	Belongs to the ABC transporter superfamily
F6O44_RS06345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6O44_RS06350	COG0601	transmembrane transport
F6O44_RS06360	COG2095	MarC family integral membrane protein
F6O44_RS06365	COG1454	alcohol dehydrogenase
F6O44_RS06365	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS06380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F6O44_RS06385	COG0745	RESPONSE REGULATOR receiver
F6O44_RS06390	COG1752	Esterase of the alpha-beta hydrolase superfamily
F6O44_RS06400	COG0788	formyltetrahydrofolate deformylase activity
F6O44_RS06420	COG1522	sequence-specific DNA binding
F6O44_RS06430	COG2181	nitrate reductase activity
F6O44_RS06435	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F6O44_RS06440	COG1140	nitrate reductase beta subunit
F6O44_RS06445	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F6O44_RS06450	COG2223	nitrite transmembrane transporter activity
F6O44_RS06455	COG3850	Histidine kinase
F6O44_RS06460	COG2197	response regulator
F6O44_RS06465	COG4932	domain protein
F6O44_RS06470	COG0243	molybdopterin cofactor binding
F6O44_RS06475	COG2146	nitrite reductase [NAD(P)H] activity
F6O44_RS06475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F6O44_RS06480	COG1116	anion transmembrane transporter activity
F6O44_RS06490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F6O44_RS06495	COG3707	response regulator
F6O44_RS06500	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F6O44_RS06510	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
F6O44_RS06515	COG4572	Cation transport regulator
F6O44_RS06520	COG0387	Pfam Sodium calcium exchanger
F6O44_RS06540	COG2890	protein-(glutamine-N5) methyltransferase activity
F6O44_RS06570	COG0659	secondary active sulfate transmembrane transporter activity
F6O44_RS06585	COG0012	GTP binding
F6O44_RS06590	COG3477	response to acidic pH
F6O44_RS06595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6O44_RS06600	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
F6O44_RS06610	COG3122	Protein conserved in bacteria
F6O44_RS06635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6O44_RS06650	COG0789	Transcriptional regulator
F6O44_RS06655	COG3272	Protein of unknown function (DUF1722)
F6O44_RS06660	COG1403	HNH endonuclease
F6O44_RS06670	COG0538	isocitrate dehydrogenase activity
F6O44_RS06675	COG1187	pseudouridine synthase activity
F6O44_RS06695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F6O44_RS06705	COG2205	protein histidine kinase activity
F6O44_RS06710	COG2850	peptidyl-arginine hydroxylation
F6O44_RS06715	COG1943	Transposase
F6O44_RS06735	COG1177	transmembrane transport
F6O44_RS06745	COG0318	PFAM AMP-dependent synthetase and ligase
F6O44_RS06750	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F6O44_RS06760	COG4591	ABC-type transport system involved in lipoprotein release permease component
F6O44_RS06765	COG1136	(ABC) transporter
F6O44_RS06770	COG4591	ABC-type transport system involved in lipoprotein release permease component
F6O44_RS06775	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F6O44_RS06780	COG1388	LysM domain
F6O44_RS06780	COG1376	ErfK ybiS ycfS ynhG family protein
F6O44_RS06790	COG1309	transcriptional regulator
F6O44_RS06800	COG3134	Outer membrane lipoprotein
F6O44_RS06805	COG1252	NADH dehydrogenase
F6O44_RS06825	COG0510	thiamine kinase activity
F6O44_RS06835	COG5633	Lipoprotein
F6O44_RS06840	COG0537	adenosine 5'-monophosphoramidase activity
F6O44_RS06845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6O44_RS06845	COG1263	PTS System
F6O44_RS06850	COG0084	hydrolase, TatD family'
F6O44_RS06855	COG0470	DNA polymerase III
F6O44_RS06865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F6O44_RS06870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F6O44_RS06875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F6O44_RS06885	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS06890	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F6O44_RS06910	COG1399	metal-binding, possibly nucleic acid-binding protein
F6O44_RS06925	COG1530	ribonuclease E activity
F6O44_RS06930	COG0583	DNA-binding transcription factor activity
F6O44_RS06935	COG2814	Major facilitator Superfamily
F6O44_RS06945	COG0673	inositol 2-dehydrogenase activity
F6O44_RS06955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F6O44_RS07000	COG1560	Kdo2-lipid A biosynthetic process
F6O44_RS07015	COG5645	(Lipo)protein
F6O44_RS07055	COG3381	protein complex oligomerization
F6O44_RS07080	COG0583	DNA-binding transcription factor activity
F6O44_RS07090	COG1335	isochorismatase
F6O44_RS07105	COG1702	phosphate starvation-inducible protein PhoH
F6O44_RS07115	COG2822	iron ion transport
F6O44_RS07125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F6O44_RS07135	COG0628	permease
F6O44_RS07140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F6O44_RS07155	COG1309	transcriptional regulator
F6O44_RS07200	COG3729	General stress protein
F6O44_RS07270	COG0174	glutamine synthetase
F6O44_RS07275	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F6O44_RS07280	COG1917	Cupin 2, conserved barrel domain protein
F6O44_RS07280	COG1396	sequence-specific DNA binding
F6O44_RS07285	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS07290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F6O44_RS07295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F6O44_RS07300	COG0583	DNA-binding transcription factor activity
F6O44_RS07305	COG0473	3-isopropylmalate dehydrogenase activity
F6O44_RS07310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F6O44_RS07315	COG4638	Rieske (2fe-2S)
F6O44_RS07320	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS07325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F6O44_RS07365	COG1191	sigma factor activity
F6O44_RS07380	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
F6O44_RS07425	COG1677	Flagellar hook-basal body complex protein FliE
F6O44_RS07435	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F6O44_RS07445	COG1157	protein secretion by the type III secretion system
F6O44_RS07450	COG2882	bacterial-type flagellum organization
F6O44_RS07525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F6O44_RS07530	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F6O44_RS07535	COG1414	Transcriptional regulator
F6O44_RS07545	COG2814	Major facilitator Superfamily
F6O44_RS07595	COG4786	Flagellar basal body rod
F6O44_RS07610	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
F6O44_RS07615	COG1558	bacterial-type flagellum-dependent cell motility
F6O44_RS07620	COG1815	bacterial-type flagellum-dependent cell motility
F6O44_RS07630	COG2747	anti-sigma28 factor FlgM
F6O44_RS07635	COG3418	PFAM FlgN family protein
F6O44_RS07645	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F6O44_RS07650	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F6O44_RS07655	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
F6O44_RS07660	COG0745	RESPONSE REGULATOR receiver
F6O44_RS07670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F6O44_RS07675	COG0840	transmembrane signaling receptor activity
F6O44_RS07680	COG0840	transmembrane signaling receptor activity
F6O44_RS07685	COG0835	chemotaxis
F6O44_RS07690	COG0643	Histidine kinase
F6O44_RS07690	COG2198	Histidine kinase
F6O44_RS07695	COG1360	Flagellar Motor Protein
F6O44_RS07745	COG0583	DNA-binding transcription factor activity
F6O44_RS07760	COG0583	DNA-binding transcription factor activity
F6O44_RS07775	COG0670	Belongs to the BI1 family
F6O44_RS07800	COG1832	CoA-binding protein
F6O44_RS07810	COG0210	DNA helicase
F6O44_RS07815	COG3304	Inner membrane component domain
F6O44_RS07820	COG1289	transmembrane transporter activity
F6O44_RS07825	COG3070	regulator of competence-specific genes
F6O44_RS07845	COG1067	ATP-dependent peptidase activity
F6O44_RS07855	COG3130	regulation of translation
F6O44_RS07860	COG3009	Protein conserved in bacteria
F6O44_RS07865	COG3008	intermembrane lipid transfer
F6O44_RS07865	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F6O44_RS07870	COG2995	paraquat-inducible protein a
F6O44_RS07875	COG0488	(ABC) transporter
F6O44_RS07885	COG0633	Ferredoxin
F6O44_RS07885	COG3217	Mosc domain protein beta barrel domain protein
F6O44_RS07900	COG0431	NADPH-dependent FMN reductase
F6O44_RS07905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F6O44_RS07910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6O44_RS07915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F6O44_RS07925	COG0308	aminopeptidase N
F6O44_RS07945	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F6O44_RS07950	COG1448	Aminotransferase
F6O44_RS07955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F6O44_RS07960	COG3108	Peptidase M15
F6O44_RS07975	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
F6O44_RS07985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F6O44_RS07990	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F6O44_RS07995	COG3173	Aminoglycoside phosphotransferase
F6O44_RS08005	COG2835	tetraacyldisaccharide 4'-kinase activity
F6O44_RS08010	COG3214	Protein conserved in bacteria
F6O44_RS08025	COG2333	competence protein COMEC
F6O44_RS08025	COG0658	competence protein
F6O44_RS08035	COG0539	negative regulation of cytoplasmic translation
F6O44_RS08065	COG1944	ATP diphosphatase activity
F6O44_RS08070	COG2116	formate transmembrane transporter activity
F6O44_RS08075	COG1882	Formate acetyltransferase
F6O44_RS08080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F6O44_RS08085	COG0477	Major facilitator Superfamily
F6O44_RS08090	COG3302	dmso reductase anchor subunit
F6O44_RS08095	COG0437	4 iron, 4 sulfur cluster binding
F6O44_RS08100	COG0243	molybdopterin cofactor binding
F6O44_RS08110	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F6O44_RS08130	COG0492	ferredoxin-NADP+ reductase activity
F6O44_RS08135	COG4988	ABC transporter
F6O44_RS08140	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F6O44_RS08160	COG0542	response to heat
F6O44_RS08170	COG1278	Cold shock
F6O44_RS08180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6O44_RS08185	COG2990	Protein conserved in bacteria
F6O44_RS08190	COG3593	DNA synthesis involved in DNA repair
F6O44_RS08200	COG2431	L-lysine efflux transmembrane transporter activity
F6O44_RS08210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F6O44_RS08220	COG0028	Belongs to the TPP enzyme family
F6O44_RS08225	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
F6O44_RS08230	COG0702	epimerase
F6O44_RS08235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F6O44_RS08245	COG3023	N-Acetylmuramoyl-L-alanine amidase
F6O44_RS08250	COG3706	GGDEF domain
F6O44_RS08250	COG4251	negative regulation of phosphorylation
F6O44_RS08250	COG2203	Gaf domain
F6O44_RS08250	COG5001	Diguanylate cyclase
F6O44_RS08260	COG2067	long-chain fatty acid transport protein
F6O44_RS08270	COG1126	abc transporter atp-binding protein
F6O44_RS08275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6O44_RS08280	COG4215	(ABC) transporter
F6O44_RS08285	COG4160	amino acid transport
F6O44_RS08290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6O44_RS08295	COG5002	protein histidine kinase activity
F6O44_RS08300	COG0745	RESPONSE REGULATOR receiver
F6O44_RS08305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F6O44_RS08320	COG1177	transmembrane transport
F6O44_RS08325	COG1176	ABC-type spermidine putrescine transport system, permease component I
F6O44_RS08330	COG3842	ATPase activity
F6O44_RS08335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F6O44_RS08350	COG0778	Nitroreductase
F6O44_RS08385	COG0300	oxidoreductase activity
F6O44_RS08390	COG3226	Transcriptional regulator
F6O44_RS08395	COG0738	Major facilitator superfamily
F6O44_RS08400	COG0561	phosphatase activity
F6O44_RS08405	COG2814	Major facilitator Superfamily
F6O44_RS08415	COG0671	phosphoesterase, PA-phosphatase related
F6O44_RS08425	COG1686	Belongs to the peptidase S11 family
F6O44_RS08430	COG0625	glutathione transferase activity
F6O44_RS08435	COG2133	pyrroloquinoline quinone binding
F6O44_RS08460	COG0747	negative chemotaxis
F6O44_RS08470	COG1446	asparaginase
F6O44_RS08480	COG0303	'Molybdopterin
F6O44_RS08485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F6O44_RS08490	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F6O44_RS08495	COG1882	Formate acetyltransferase
F6O44_RS08500	COG0561	phosphatase activity
F6O44_RS08510	COG1609	Transcriptional regulator
F6O44_RS08515	COG2271	Major facilitator Superfamily
F6O44_RS08525	COG0488	(ABC) transporter
F6O44_RS08535	COG1376	ErfK ybiS ycfS ynhG family protein
F6O44_RS08545	COG2723	6-phospho-beta-galactosidase activity
F6O44_RS08550	COG0667	Aldo Keto reductase
F6O44_RS08555	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F6O44_RS08560	COG1321	iron dependent repressor
F6O44_RS08570	COG2194	sulfuric ester hydrolase activity
F6O44_RS08575	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F6O44_RS08590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6O44_RS08595	COG0765	amino acid transport
F6O44_RS08600	COG1126	abc transporter atp-binding protein
F6O44_RS08605	COG0668	transmembrane transport
F6O44_RS08615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F6O44_RS08625	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F6O44_RS08635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F6O44_RS08645	COG0513	Belongs to the DEAD box helicase family
F6O44_RS08650	COG1309	transcriptional regulator
F6O44_RS08660	COG1131	(ABC) transporter
F6O44_RS08665	COG0842	Transport permease protein
F6O44_RS08680	COG3568	Endonuclease Exonuclease Phosphatase
F6O44_RS08685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F6O44_RS08690	COG0392	lysyltransferase activity
F6O44_RS08695	COG0670	Belongs to the BI1 family
F6O44_RS08700	COG0314	molybdopterin synthase activity
F6O44_RS08705	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F6O44_RS08715	COG0521	Mo-molybdopterin cofactor biosynthetic process
F6O44_RS08740	COG0745	RESPONSE REGULATOR receiver
F6O44_RS08765	COG2226	methyltransferase
F6O44_RS08780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F6O44_RS08785	COG1881	PFAM PEBP family protein
F6O44_RS08820	COG4677	pectinesterase activity
F6O44_RS08830	COG1595	DNA-templated transcription, initiation
F6O44_RS08855	COG0789	Transcriptional regulator
F6O44_RS08860	COG2200	EAL domain
F6O44_RS08885	COG0561	phosphatase activity
F6O44_RS08895	COG4149	molybdate abc transporter
F6O44_RS08900	COG0725	ABC transporter, periplasmic molybdate-binding protein
F6O44_RS08910	COG2005	Transcriptional regulator
F6O44_RS08910	COG3585	molybdate ion transport
F6O44_RS08915	COG1119	ATPase activity
F6O44_RS08920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F6O44_RS08925	COG1085	galactose-1-phosphate uridylyltransferase
F6O44_RS08935	COG2017	converts alpha-aldose to the beta-anomer
F6O44_RS08945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F6O44_RS08955	COG1230	cation diffusion facilitator family transporter
F6O44_RS08965	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F6O44_RS09005	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
F6O44_RS09010	COG2885	chlorophyll binding
F6O44_RS09020	COG3064	Membrane
F6O44_RS09025	COG0848	biopolymer transport protein
F6O44_RS09030	COG0811	peptide transport
F6O44_RS09035	COG0824	Thioesterase
F6O44_RS09040	COG3790	cyd operon protein YbgE
F6O44_RS09045	COG4890	Cyd operon protein YbgT
F6O44_RS09050	COG1294	oxidase, subunit
F6O44_RS09055	COG1271	oxidase subunit
F6O44_RS09065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F6O44_RS09075	COG0508	dehydrogenase complex catalyzes the overall conversion of
F6O44_RS09080	COG0567	Dehydrogenase, E1 component
F6O44_RS09085	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F6O44_RS09090	COG1053	succinate dehydrogenase
F6O44_RS09095	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F6O44_RS09100	COG2009	succinate dehydrogenase
F6O44_RS09105	COG0372	Belongs to the citrate synthase family
F6O44_RS09135	COG1984	allophanate hydrolase subunit 2
F6O44_RS09140	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F6O44_RS09145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F6O44_RS09155	COG0415	Belongs to the DNA photolyase family
F6O44_RS09185	COG2205	protein histidine kinase activity
F6O44_RS09190	COG0745	RESPONSE REGULATOR receiver
F6O44_RS09195	COG0033	Phosphoglucomutase
F6O44_RS09205	COG0596	Alpha beta hydrolase
F6O44_RS09220	COG0735	belongs to the Fur family
F6O44_RS09225	COG0583	DNA-binding transcription factor activity
F6O44_RS09230	COG1053	succinate dehydrogenase
F6O44_RS09275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F6O44_RS09280	COG1846	Transcriptional regulator
F6O44_RS09280	COG1940	carbohydrate kinase activity
F6O44_RS09285	COG0647	UMP catabolic process
F6O44_RS09290	COG0367	asparagine synthase
F6O44_RS09330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F6O44_RS09340	COG1702	phosphate starvation-inducible protein PhoH
F6O44_RS09365	COG0765	amino acid transport
F6O44_RS09370	COG0765	amino acid transport
F6O44_RS09375	COG1126	abc transporter atp-binding protein
F6O44_RS09380	COG2831	hemolysin activation secretion protein
F6O44_RS09390	COG2888	peptidyl-tyrosine sulfation
F6O44_RS09405	COG1466	dna polymerase III delta subunit
F6O44_RS09415	COG0406	alpha-ribazole phosphatase activity
F6O44_RS09420	COG0799	negative regulation of ribosome biogenesis
F6O44_RS09430	COG0768	penicillin binding
F6O44_RS09435	COG0772	Belongs to the SEDS family
F6O44_RS09440	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F6O44_RS09445	COG1686	Belongs to the peptidase S11 family
F6O44_RS09460	COG0583	DNA-binding transcription factor activity
F6O44_RS09475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F6O44_RS09495	COG3069	C4-dicarboxylate transmembrane transporter activity
F6O44_RS09500	COG3719	Belongs to the RNase T2 family
F6O44_RS09505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F6O44_RS09515	COG3634	alkyl hydroperoxide reductase activity
F6O44_RS09525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F6O44_RS09535	COG0583	DNA-binding transcription factor activity
F6O44_RS09540	COG3969	phosphoadenosine phosphosulfate
F6O44_RS09545	COG1475	DNA binding
F6O44_RS09550	COG0436	Aminotransferase
F6O44_RS09560	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
F6O44_RS09585	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6O44_RS09590	COG1129	ABC transporter
F6O44_RS09605	COG2879	small protein
F6O44_RS09610	COG1966	Carbon starvation protein
F6O44_RS09620	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS09625	COG1535	isochorismatase
F6O44_RS09625	COG3433	isochorismatase activity
F6O44_RS09630	COG1021	2,3-dihydroxybenzoate-AMP ligase
F6O44_RS09635	COG1169	isochorismate synthase
F6O44_RS09640	COG4592	Periplasmic binding protein
F6O44_RS09650	COG0477	Major facilitator Superfamily
F6O44_RS09655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6O44_RS09660	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6O44_RS09665	COG1120	ATPase activity
F6O44_RS09670	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F6O44_RS09670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F6O44_RS09675	COG3251	PFAM MbtH domain protein
F6O44_RS09680	COG2382	esterase
F6O44_RS09685	COG4771	TonB-dependent receptor
F6O44_RS09690	COG3958	Transketolase
F6O44_RS09695	COG3959	Transketolase, thiamine diphosphate binding domain
F6O44_RS09700	COG2390	Transcriptional regulator
F6O44_RS09705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F6O44_RS09710	COG1879	ABC-type sugar transport system periplasmic component
F6O44_RS09720	COG1129	ABC transporter
F6O44_RS09725	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6O44_RS09735	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS09755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F6O44_RS09785	COG3698	Phosphodiester glycosidase
F6O44_RS09815	COG2315	Protein conserved in bacteria
F6O44_RS09820	COG0778	Nitroreductase
F6O44_RS09835	COG0477	Major facilitator Superfamily
F6O44_RS09840	COG0668	transmembrane transport
F6O44_RS09845	COG1113	amino acid transport
F6O44_RS09860	COG1252	NADH dehydrogenase
F6O44_RS09870	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS09875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F6O44_RS09885	COG0531	amino acid
F6O44_RS09935	COG0667	Aldo Keto reductase
F6O44_RS09940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6O44_RS09945	COG1473	amidohydrolase
F6O44_RS09965	COG1566	PFAM secretion protein HlyD family protein
F6O44_RS09980	COG0583	DNA-binding transcription factor activity
F6O44_RS09990	COG0666	response to abiotic stimulus
F6O44_RS10000	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F6O44_RS10005	COG1304	FMN binding
F6O44_RS10010	COG0549	Belongs to the carbamate kinase family
F6O44_RS10015	COG0402	S-adenosylhomocysteine deaminase activity
F6O44_RS10025	COG3104	oligopeptide transport
F6O44_RS10035	COG0531	amino acid
F6O44_RS10045	COG3710	Transcriptional regulator
F6O44_RS10050	COG1902	pentaerythritol trinitrate reductase activity
F6O44_RS10060	COG1560	Kdo2-lipid A biosynthetic process
F6O44_RS10125	COG0583	DNA-binding transcription factor activity
F6O44_RS10165	COG2501	S4 domain
F6O44_RS10175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F6O44_RS10185	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F6O44_RS10190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F6O44_RS10205	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F6O44_RS10210	COG4181	ATPase activity
F6O44_RS10215	COG2755	lipolytic protein G-D-S-L family
F6O44_RS10220	COG0300	oxidoreductase activity
F6O44_RS10225	COG3118	belongs to the thioredoxin family
F6O44_RS10230	COG0390	transport system, permease component
F6O44_RS10235	COG4619	ABC transporter
F6O44_RS10240	COG0330	HflC and HflK could
F6O44_RS10245	COG1585	Membrane protein implicated in regulation of membrane protease activity
F6O44_RS10260	COG3735	TraB family
F6O44_RS10265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F6O44_RS10275	COG2223	nitrite transmembrane transporter activity
F6O44_RS10280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F6O44_RS10280	COG4651	solute:proton antiporter activity
F6O44_RS10285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6O44_RS10325	COG2832	Protein of unknown function (DUF454)
F6O44_RS10330	COG3923	Primosomal replication protein n
F6O44_RS10340	COG3264	Mechanosensitive ion channel
F6O44_RS10340	COG1196	nuclear chromosome segregation
F6O44_RS10345	COG1309	transcriptional regulator
F6O44_RS10350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6O44_RS10355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6O44_RS10370	COG0110	maltose O-acetyltransferase activity
F6O44_RS10395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F6O44_RS10405	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F6O44_RS10410	COG5507	3-demethylubiquinone-9 3-methyltransferase
F6O44_RS10415	COG2364	Membrane
F6O44_RS10445	COG3695	enzyme binding
F6O44_RS10450	COG3126	Type III secretion system lipoprotein chaperone (YscW)
F6O44_RS10455	COG1946	Acyl-CoA thioesterase
F6O44_RS10460	COG0583	DNA-binding transcription factor activity
F6O44_RS10465	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F6O44_RS10470	COG0004	ammonium transporteR
F6O44_RS10475	COG0347	Belongs to the P(II) protein family
F6O44_RS10480	COG1132	(ABC) transporter
F6O44_RS10485	COG1132	(ABC) transporter
F6O44_RS10490	COG1522	sequence-specific DNA binding
F6O44_RS10505	COG4533	DNA binding
F6O44_RS10515	COG0824	Thioesterase
F6O44_RS10520	COG1555	photosystem II stabilization
F6O44_RS10530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F6O44_RS10535	COG0776	regulation of translation
F6O44_RS10540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F6O44_RS10575	COG0271	Belongs to the BolA IbaG family
F6O44_RS10585	COG3056	Lipoprotein
F6O44_RS10590	COG2223	nitrite transmembrane transporter activity
F6O44_RS10595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F6O44_RS10600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F6O44_RS10605	COG1845	cytochrome c oxidase, subunit III
F6O44_RS10610	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F6O44_RS10625	COG2814	Major facilitator Superfamily
F6O44_RS10655	COG2177	Part of the ABC transporter FtsEX involved in
F6O44_RS10680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F6O44_RS10695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F6O44_RS10700	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS10705	COG0736	holo-[acyl-carrier-protein] synthase activity
F6O44_RS10710	COG2831	hemolysin activation secretion protein
F6O44_RS10725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F6O44_RS10750	COG0142	geranyltranstransferase activity
F6O44_RS10760	COG0667	Aldo Keto reductase
F6O44_RS10765	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F6O44_RS10770	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F6O44_RS10785	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F6O44_RS10785	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F6O44_RS10795	COG4238	major outer membrane lipoprotein
F6O44_RS10800	COG3248	Nucleoside-binding outer membrane protein
F6O44_RS10825	COG1862	Preprotein translocase
F6O44_RS10850	COG1574	metal-dependent hydrolase with the TIM-barrel fold
F6O44_RS10860	COG1335	isochorismatase
F6O44_RS10865	COG0583	DNA-binding transcription factor activity
F6O44_RS10870	COG0366	Alpha amylase catalytic
F6O44_RS10895	COG0420	3'-5' exonuclease activity
F6O44_RS10900	COG0419	ATPase involved in DNA repair
F6O44_RS10905	COG1940	carbohydrate kinase activity
F6O44_RS10920	COG4126	flavin adenine dinucleotide binding
F6O44_RS10930	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F6O44_RS10935	COG3416	Protein conserved in bacteria
F6O44_RS10945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F6O44_RS10955	COG1785	Belongs to the alkaline phosphatase family
F6O44_RS10990	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F6O44_RS11000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F6O44_RS11005	COG0113	porphobilinogen synthase activity
F6O44_RS11010	COG1943	Transposase
F6O44_RS11030	COG2175	clavaminate synthase activity
F6O44_RS11035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F6O44_RS11040	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F6O44_RS11045	COG4521	taurine ABC transporter
F6O44_RS11050	COG2040	homocysteine
F6O44_RS11055	COG0833	amino acid
F6O44_RS11065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6O44_RS11075	COG0765	amino acid transport
F6O44_RS11080	COG0765	amino acid transport
F6O44_RS11085	COG0583	DNA-binding transcription factor activity
F6O44_RS11090	COG2271	Major facilitator Superfamily
F6O44_RS11110	COG3188	usher protein
F6O44_RS11135	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
F6O44_RS11145	COG3639	organic phosphonate transmembrane transporter activity
F6O44_RS11165	COG0791	NLP P60 protein
F6O44_RS11225	COG3121	Chaperone
F6O44_RS11250	COG0579	oxidoreductase
F6O44_RS11255	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS11260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F6O44_RS11265	COG1113	amino acid transport
F6O44_RS11270	COG1802	Transcriptional regulator
F6O44_RS11285	COG0583	DNA-binding transcription factor activity
F6O44_RS11295	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS11310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F6O44_RS11320	COG1596	polysaccharide export
F6O44_RS11340	COG0463	Glycosyl transferase, family 2
F6O44_RS11345	COG0438	transferase activity, transferring glycosyl groups
F6O44_RS11350	COG0297	glycogen (starch) synthase activity
F6O44_RS11350	COG0438	transferase activity, transferring glycosyl groups
F6O44_RS11365	COG1045	serine acetyltransferase
F6O44_RS11395	COG0454	-acetyltransferase
F6O44_RS11410	COG2991	Protein conserved in bacteria
F6O44_RS11425	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F6O44_RS11430	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F6O44_RS11445	COG3034	peptidoglycan biosynthetic process
F6O44_RS11450	COG0121	glutamine amidotransferase
F6O44_RS11460	COG1960	acyl-CoA dehydrogenase activity
F6O44_RS11465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F6O44_RS11475	COG0583	DNA-binding transcription factor activity
F6O44_RS11485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F6O44_RS11495	COG2226	methyltransferase
F6O44_RS11505	COG0741	lytic transglycosylase activity
F6O44_RS11505	COG1388	LysM domain
F6O44_RS11510	COG2226	methyltransferase
F6O44_RS11520	COG2814	Major facilitator Superfamily
F6O44_RS11525	COG0583	DNA-binding transcription factor activity
F6O44_RS11530	COG0656	L-ascorbic acid biosynthetic process
F6O44_RS11565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F6O44_RS11575	COG2011	ABC-type metal ion transport system permease component
F6O44_RS11580	COG1464	Belongs to the NlpA lipoprotein family
F6O44_RS11590	COG1720	tRNA m6t6A37 methyltransferase activity
F6O44_RS11600	COG3015	lipoprotein NlpE involved in copper resistance
F6O44_RS11605	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F6O44_RS11620	COG4568	rho-dependent transcription termination
F6O44_RS11625	COG0037	tRNA processing
F6O44_RS11630	COG0346	lactoylglutathione lyase activity
F6O44_RS11635	COG1982	Orn Lys Arg decarboxylase major
F6O44_RS11690	COG0750	zinc metalloprotease
F6O44_RS11695	COG0575	Belongs to the CDS family
F6O44_RS11710	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F6O44_RS11735	COG0024	Methionine aminopeptidase
F6O44_RS11740	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F6O44_RS11760	COG3835	regulator
F6O44_RS11785	COG2860	membrane
F6O44_RS11805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6O44_RS11810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F6O44_RS11815	COG1120	ATPase activity
F6O44_RS11820	COG4774	siderophore transport
F6O44_RS11825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F6O44_RS11835	COG1643	Atp-dependent helicase
F6O44_RS11840	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F6O44_RS11865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F6O44_RS11880	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
F6O44_RS11885	COG0726	polysaccharide deacetylase
F6O44_RS11890	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS11895	COG0842	Transport permease protein
F6O44_RS11900	COG1131	(ABC) transporter
F6O44_RS11905	COG0288	reversible hydration of carbon dioxide
F6O44_RS11915	COG4993	Dehydrogenase
F6O44_RS11920	COG2132	Multicopper oxidase
F6O44_RS11935	COG0545	Peptidyl-prolyl cis-trans isomerase
F6O44_RS11955	COG1049	propionate catabolic process, 2-methylcitrate cycle
F6O44_RS11960	COG3064	Membrane
F6O44_RS11975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F6O44_RS11980	COG0508	dehydrogenase complex catalyzes the overall conversion of
F6O44_RS11985	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F6O44_RS11990	COG2186	Transcriptional regulator
F6O44_RS11995	COG1113	amino acid transport
F6O44_RS12000	COG2211	Major facilitator Superfamily
F6O44_RS12005	COG3940	Belongs to the glycosyl hydrolase 43 family
F6O44_RS12010	COG3725	Membrane protein required for beta-lactamase induction
F6O44_RS12025	COG4969	Belongs to the N-Me-Phe pilin family
F6O44_RS12030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F6O44_RS12035	COG1459	type II secretion system
F6O44_RS12060	COG0494	nUDIX hydrolase
F6O44_RS12080	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F6O44_RS12085	COG0849	cell division
F6O44_RS12095	COG1181	Belongs to the D-alanine--D-alanine ligase family
F6O44_RS12110	COG0772	Belongs to the SEDS family
F6O44_RS12125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F6O44_RS12130	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F6O44_RS12135	COG0768	penicillin binding
F6O44_RS12165	COG0028	Belongs to the TPP enzyme family
F6O44_RS12215	COG0738	Major facilitator superfamily
F6O44_RS12225	COG0583	DNA-binding transcription factor activity
F6O44_RS12230	COG2271	Major facilitator Superfamily
F6O44_RS12255	COG1178	ABC-type Fe3 transport system permease component
F6O44_RS12265	COG0586	Pfam SNARE associated Golgi protein
F6O44_RS12285	COG0235	Class ii aldolase
F6O44_RS12290	COG0417	DNA replication proofreading
F6O44_RS12300	COG0564	pseudouridine synthase activity
F6O44_RS12310	COG3493	citrate carrier protein
F6O44_RS12325	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F6O44_RS12330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F6O44_RS12340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F6O44_RS12390	COG0505	Belongs to the CarA family
F6O44_RS12455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F6O44_RS12465	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F6O44_RS12470	COG0471	metal ion transport
F6O44_RS12475	COG0471	metal ion transport
F6O44_RS12480	COG2828	Protein conserved in bacteria
F6O44_RS12490	COG0583	DNA-binding transcription factor activity
F6O44_RS12505	COG1047	Peptidyl-prolyl cis-trans
F6O44_RS12510	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F6O44_RS12520	COG0196	riboflavin kinase activity
F6O44_RS12535	COG0583	DNA-binding transcription factor activity
F6O44_RS12555	COG3121	Chaperone
F6O44_RS12560	COG3539	Fimbrial protein
F6O44_RS12575	COG3188	usher protein
F6O44_RS12585	COG3539	Fimbrial protein
F6O44_RS12625	COG0583	DNA-binding transcription factor activity
F6O44_RS12640	COG1584	GPR1 FUN34 yaaH family protein
F6O44_RS12650	COG0521	Mo-molybdopterin cofactor biosynthetic process
F6O44_RS12655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F6O44_RS12660	COG1115	amino acid carrier protein
F6O44_RS12670	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F6O44_RS12680	COG0527	aspartate kinase activity
F6O44_RS12680	COG0460	homoserine dehydrogenase
F6O44_RS12690	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F6O44_RS12700	COG0745	RESPONSE REGULATOR receiver
F6O44_RS12705	COG4452	Inner membrane protein CreD
F6O44_RS12710	COG2205	protein histidine kinase activity
F6O44_RS12715	COG0745	RESPONSE REGULATOR receiver
F6O44_RS12720	COG3045	CreA protein
F6O44_RS12725	COG2207	Transcriptional regulator
F6O44_RS12725	COG3708	Transcriptional regulator
F6O44_RS12745	COG0741	lytic transglycosylase activity
F6O44_RS12750	COG0488	(ABC) transporter
F6O44_RS12760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
F6O44_RS12765	COG0560	Phosphoserine phosphatase
F6O44_RS12770	COG3726	membrane protein affecting hemolysin expression
F6O44_RS12800	COG0084	hydrolase, TatD family'
F6O44_RS12805	COG4667	esterase of the alpha-beta hydrolase superfamily
F6O44_RS12810	COG5487	UPF0391 membrane protein
F6O44_RS12815	COG2823	Periplasmic or secreted lipoprotein
F6O44_RS12825	COG1011	Hydrolase
F6O44_RS12830	COG0456	acetyltransferase
F6O44_RS12835	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
F6O44_RS12865	COG3706	GGDEF domain
F6O44_RS12870	COG4114	ferric iron reductase
F6O44_RS12875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6O44_RS12880	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F6O44_RS12885	COG2197	response regulator
F6O44_RS12890	COG2197	response regulator
F6O44_RS12905	COG2966	Psort location CytoplasmicMembrane, score
F6O44_RS12920	COG1484	DNA-dependent DNA replication
F6O44_RS12945	COG0837	glucose binding
F6O44_RS12945	COG1737	Transcriptional regulator
F6O44_RS12950	COG0800	Aldolase
F6O44_RS12955	COG3734	2-keto-3-deoxy-galactonokinase
F6O44_RS12970	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F6O44_RS12990	COG0531	amino acid
F6O44_RS12995	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS13000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F6O44_RS13015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F6O44_RS13015	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
F6O44_RS13030	COG1846	Transcriptional regulator
F6O44_RS13040	COG0179	Fumarylacetoacetate (FAA) hydrolase
F6O44_RS13050	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS13055	COG3384	dioxygenase
F6O44_RS13065	COG3971	2-oxopent-4-enoate hydratase activity
F6O44_RS13085	COG2368	4-hydroxyphenylacetate
F6O44_RS13090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F6O44_RS13115	COG3210	domain, Protein
F6O44_RS13125	COG3210	domain, Protein
F6O44_RS13130	COG2831	hemolysin activation secretion protein
F6O44_RS13135	COG1966	Carbon starvation protein
F6O44_RS13140	COG2879	small protein
F6O44_RS13145	COG0523	cobalamin synthesis protein
F6O44_RS13150	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS13155	COG2733	membrane
F6O44_RS13160	COG2814	Major facilitator Superfamily
F6O44_RS13170	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
F6O44_RS13175	COG1924	4 iron, 4 sulfur cluster binding
F6O44_RS13190	COG1566	PFAM secretion protein HlyD family protein
F6O44_RS13200	COG5457	Domain of unknown function (DUF1127)
F6O44_RS13205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F6O44_RS13215	COG0531	amino acid
F6O44_RS13235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6O44_RS13235	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS13240	COG3715	PTS system
F6O44_RS13245	COG3716	PTS system mannose fructose sorbose family IID component
F6O44_RS13290	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS13290	COG1454	alcohol dehydrogenase
F6O44_RS13305	COG1882	Formate acetyltransferase
F6O44_RS13310	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F6O44_RS13320	COG4869	propanediol catabolic process
F6O44_RS13345	COG3706	GGDEF domain
F6O44_RS13350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6O44_RS13355	COG0842	Transport permease protein
F6O44_RS13355	COG1129	ABC transporter
F6O44_RS13360	COG0842	Transport permease protein
F6O44_RS13395	COG2850	peptidyl-arginine hydroxylation
F6O44_RS13400	COG5002	protein histidine kinase activity
F6O44_RS13405	COG0745	RESPONSE REGULATOR receiver
F6O44_RS13410	COG1538	Outer membrane efflux protein
F6O44_RS13415	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6O44_RS13420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6O44_RS13425	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6O44_RS13470	COG2003	Belongs to the UPF0758 family
F6O44_RS13490	COG3596	GTP binding
F6O44_RS13515	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F6O44_RS13520	COG0732	type I restriction modification DNA specificity domain
F6O44_RS13530	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F6O44_RS13545	COG0582	viral genome integration into host DNA
F6O44_RS13555	COG0288	reversible hydration of carbon dioxide
F6O44_RS13560	COG0659	secondary active sulfate transmembrane transporter activity
F6O44_RS13565	COG1064	alcohol dehydrogenase
F6O44_RS13570	COG1175	transmembrane transport
F6O44_RS13575	COG0395	ABC-type sugar transport system, permease component
F6O44_RS13580	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F6O44_RS13585	COG3842	ATPase activity
F6O44_RS13595	COG2814	Major facilitator Superfamily
F6O44_RS13605	COG1082	Xylose isomerase domain protein TIM barrel
F6O44_RS13615	COG3962	Belongs to the TPP enzyme family
F6O44_RS13620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6O44_RS13625	COG1737	Transcriptional regulator
F6O44_RS13625	COG0837	glucose binding
F6O44_RS13630	COG3718	enzyme involved in inositol metabolism
F6O44_RS13645	COG0433	COG0433 Predicted ATPase
F6O44_RS13650	COG0795	lipopolysaccharide-transporting ATPase activity
F6O44_RS13655	COG0795	lipopolysaccharide-transporting ATPase activity
F6O44_RS13665	COG2927	DNA polymerase III (CHI subunit)
F6O44_RS13670	COG0525	valine-tRNA ligase activity
F6O44_RS13690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F6O44_RS13695	COG2731	YhcH YjgK YiaL family protein
F6O44_RS13715	COG0251	oxidation-reduction process
F6O44_RS13720	COG3525	Glycosyl hydrolase, family 20, catalytic domain
F6O44_RS13730	COG1609	Transcriptional regulator
F6O44_RS13735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6O44_RS13735	COG1263	PTS System
F6O44_RS13740	COG0366	Alpha amylase catalytic
F6O44_RS13745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6O44_RS13750	COG1486	melibiose metabolic process
F6O44_RS13775	COG0602	queuosine metabolic process
F6O44_RS13780	COG3711	transcriptional antiterminator
F6O44_RS13780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS13785	COG2706	6-phosphogluconolactonase activity
F6O44_RS13800	COG3964	amidohydrolase
F6O44_RS13835	COG0312	modulator of DNA gyrase
F6O44_RS13850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F6O44_RS13860	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6O44_RS13865	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6O44_RS13870	COG1129	ABC transporter
F6O44_RS13875	COG1879	ABC-type sugar transport system periplasmic component
F6O44_RS13885	COG2105	PFAM AIG2 family protein
F6O44_RS13890	COG2911	Protein conserved in bacteria
F6O44_RS13895	COG0729	surface antigen
F6O44_RS13905	COG1253	flavin adenine dinucleotide binding
F6O44_RS13915	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
F6O44_RS13930	COG1733	regulation of RNA biosynthetic process
F6O44_RS13935	COG0702	epimerase
F6O44_RS13945	COG0697	spore germination
F6O44_RS13955	COG1113	amino acid transport
F6O44_RS13960	COG0545	Peptidyl-prolyl cis-trans isomerase
F6O44_RS13965	COG3061	Opacity-associated protein A
F6O44_RS13975	COG0359	binds to the 23S rRNA
F6O44_RS13980	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F6O44_RS13985	COG2965	DNA replication, synthesis of RNA primer
F6O44_RS14045	COG1073	alpha beta
F6O44_RS14050	COG3650	response to hydrogen peroxide
F6O44_RS14060	COG1960	acyl-CoA dehydrogenase activity
F6O44_RS14065	COG0477	Major facilitator Superfamily
F6O44_RS14070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F6O44_RS14075	COG0557	exoribonuclease II activity
F6O44_RS14090	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
F6O44_RS14100	COG0330	HflC and HflK could
F6O44_RS14105	COG0330	HflC and HflK could
F6O44_RS14110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F6O44_RS14130	COG0860	N-Acetylmuramoyl-L-alanine amidase
F6O44_RS14135	COG0802	atpase or kinase
F6O44_RS14140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F6O44_RS14140	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F6O44_RS14145	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F6O44_RS14165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6O44_RS14170	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F6O44_RS14185	COG3264	Mechanosensitive ion channel
F6O44_RS14185	COG1511	domain protein
F6O44_RS14200	COG1053	succinate dehydrogenase
F6O44_RS14205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F6O44_RS14225	COG2076	Multidrug Resistance protein
F6O44_RS14230	COG5510	response to toxic substance
F6O44_RS14245	COG1509	lysine 2,3-aminomutase activity
F6O44_RS14300	COG0459	protein refolding
F6O44_RS14310	COG0531	amino acid
F6O44_RS14315	COG3030	protein affecting phage T7 exclusion by the F plasmid
F6O44_RS14320	COG1027	Aspartate ammonia-lyase
F6O44_RS14325	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F6O44_RS14340	COG1309	transcriptional regulator
F6O44_RS14375	COG0457	Tetratricopeptide repeat
F6O44_RS14380	COG0726	polysaccharide deacetylase
F6O44_RS14380	COG1649	PFAM Uncharacterised BCR, COG1649
F6O44_RS14385	COG1215	transferase activity, transferring glycosyl groups
F6O44_RS14400	COG0861	Integral membrane protein TerC family
F6O44_RS14435	COG1486	melibiose metabolic process
F6O44_RS14440	COG2169	Transcriptional regulator
F6O44_RS14455	COG2824	Alkylphosphonate utilization operon protein PhnA
F6O44_RS14460	COG2764	glyoxalase bleomycin resistance protein dioxygenase
F6O44_RS14465	COG2188	Transcriptional regulator
F6O44_RS14470	COG3624	Phosphonate C-P lyase system protein PhnG
F6O44_RS14475	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F6O44_RS14480	COG3626	phosphonate metabolism
F6O44_RS14485	COG3627	carbon phosphorus lyase activity
F6O44_RS14490	COG4107	phosphonate C-P lyase system protein PhnK
F6O44_RS14495	COG4778	phosphonate C-P lyase system protein PhnL
F6O44_RS14500	COG3454	Phosphonate metabolism
F6O44_RS14510	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F6O44_RS14520	COG0784	Response regulator, receiver
F6O44_RS14520	COG4191	Histidine kinase
F6O44_RS14525	COG1129	ABC transporter
F6O44_RS14530	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6O44_RS14555	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F6O44_RS14560	COG1301	dicarboxylic acid transport
F6O44_RS14570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F6O44_RS14575	COG3162	membrane
F6O44_RS14585	COG3539	Fimbrial protein
F6O44_RS14590	COG3539	Fimbrial protein
F6O44_RS14605	COG3539	Fimbrial protein
F6O44_RS14610	COG1346	cytolysis
F6O44_RS14620	COG0583	DNA-binding transcription factor activity
F6O44_RS14625	COG0025	NhaP-type Na H and K H
F6O44_RS14630	COG2252	PERMEase
F6O44_RS14640	COG0625	glutathione transferase activity
F6O44_RS14645	COG0789	Transcriptional regulator
F6O44_RS14655	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F6O44_RS14670	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
F6O44_RS14680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F6O44_RS14695	COG2315	Protein conserved in bacteria
F6O44_RS14700	COG0432	Pfam Uncharacterised protein family UPF0047
F6O44_RS14710	COG1448	Aminotransferase
F6O44_RS14715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F6O44_RS14720	COG0305	Participates in initiation and elongation during chromosome replication
F6O44_RS14735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F6O44_RS14745	COG0735	belongs to the Fur family
F6O44_RS14750	COG3237	CsbD-like
F6O44_RS14755	COG0534	Mate efflux family protein
F6O44_RS14765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F6O44_RS14790	COG4580	involved in the transport of maltose and maltodextrins
F6O44_RS14840	COG0251	oxidation-reduction process
F6O44_RS14845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F6O44_RS14855	COG0527	aspartate kinase activity
F6O44_RS14860	COG3541	Predicted nucleotidyltransferase
F6O44_RS14865	COG1690	Belongs to the RtcB family
F6O44_RS14880	COG4650	regulator
F6O44_RS14895	COG1187	pseudouridine synthase activity
F6O44_RS14910	COG1283	sodium-dependent phosphate transmembrane transporter activity
F6O44_RS14915	COG1410	methionine synthase
F6O44_RS14915	COG0646	methionine synthase
F6O44_RS14935	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F6O44_RS14980	COG0151	Belongs to the GarS family
F6O44_RS14990	COG4191	Histidine kinase
F6O44_RS14995	COG3678	ATP-independent chaperone mediated protein folding
F6O44_RS15030	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
F6O44_RS15045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F6O44_RS15050	COG2104	thiamine diphosphate biosynthetic process
F6O44_RS15070	COG3706	GGDEF domain
F6O44_RS15080	COG1447	Phosphotransferase system cellobiose-specific component IIA
F6O44_RS15085	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F6O44_RS15120	COG0250	Participates in transcription elongation, termination and antitermination
F6O44_RS15225	COG0583	DNA-binding transcription factor activity
F6O44_RS15240	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F6O44_RS15255	COG3443	Belongs to the bacterial solute-binding protein 9 family
F6O44_RS15260	COG2207	Transcriptional regulator
F6O44_RS15270	COG0371	Dehydrogenase
F6O44_RS15275	COG0697	spore germination
F6O44_RS15285	COG0460	homoserine dehydrogenase
F6O44_RS15285	COG0527	aspartate kinase activity
F6O44_RS15290	COG0626	cystathionine gamma-synthase activity
F6O44_RS15305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F6O44_RS15310	COG1609	Transcriptional regulator
F6O44_RS15315	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F6O44_RS15330	COG1575	Belongs to the MenA family. Type 1 subfamily
F6O44_RS15350	COG3678	ATP-independent chaperone mediated protein folding
F6O44_RS15355	COG0745	RESPONSE REGULATOR receiver
F6O44_RS15360	COG2205	protein histidine kinase activity
F6O44_RS15365	COG2258	MOSC domain
F6O44_RS15370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F6O44_RS15410	COG1454	alcohol dehydrogenase
F6O44_RS15420	COG2271	Major facilitator Superfamily
F6O44_RS15425	COG2731	YhcH YjgK YiaL family protein
F6O44_RS15430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F6O44_RS15435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6O44_RS15445	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F6O44_RS15470	COG0437	4 iron, 4 sulfur cluster binding
F6O44_RS15475	COG2864	formate dehydrogenase
F6O44_RS15485	COG0657	acetylesterase activity
F6O44_RS15490	COG0456	acetyltransferase
F6O44_RS15505	COG1011	Hydrolase
F6O44_RS15510	COG2271	Major facilitator Superfamily
F6O44_RS15515	COG1082	Xylose isomerase domain protein TIM barrel
F6O44_RS15520	COG2188	Transcriptional regulator
F6O44_RS15535	COG3852	Histidine kinase
F6O44_RS15545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F6O44_RS15585	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F6O44_RS15590	COG3084	Protein conserved in bacteria
F6O44_RS15600	COG1763	Mo-molybdopterin cofactor biosynthetic process
F6O44_RS15625	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
F6O44_RS15635	COG1739	Uncharacterized protein family UPF0029
F6O44_RS15685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F6O44_RS15695	COG3165	ubiquinone biosynthetic process from chorismate
F6O44_RS15725	COG0583	DNA-binding transcription factor activity
F6O44_RS15730	COG0697	spore germination
F6O44_RS15735	COG0561	phosphatase activity
F6O44_RS15740	COG2267	carboxylic ester hydrolase activity
F6O44_RS15745	COG1280	lysine exporter protein (LysE YggA)
F6O44_RS15755	COG1280	lysine exporter protein (LysE YggA)
F6O44_RS15770	COG2050	protein possibly involved in aromatic compounds catabolism
F6O44_RS15785	COG0210	DNA helicase
F6O44_RS15790	COG1011	Hydrolase
F6O44_RS15795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F6O44_RS15820	COG3072	Adenylate cyclase
F6O44_RS15830	COG1587	Uroporphyrinogen-III synthase
F6O44_RS15835	COG2959	enzyme of heme biosynthesis
F6O44_RS15840	COG3071	HemY protein
F6O44_RS15890	COG2244	polysaccharide biosynthetic process
F6O44_RS15895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F6O44_RS15900	COG0456	acetyltransferase
F6O44_RS15905	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F6O44_RS15910	COG1088	dTDP-glucose 4,6-dehydratase activity
F6O44_RS15915	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F6O44_RS15920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F6O44_RS15930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F6O44_RS15935	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F6O44_RS15945	COG3118	belongs to the thioredoxin family
F6O44_RS15960	COG0583	DNA-binding transcription factor activity
F6O44_RS15970	COG1811	Na channel or pump
F6O44_RS15980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F6O44_RS15995	COG0583	DNA-binding transcription factor activity
F6O44_RS16000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F6O44_RS16010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F6O44_RS16015	COG3978	acetolactate synthase activity
F6O44_RS16030	COG0606	chelatase, subunit chli
F6O44_RS16035	COG3085	chromosome segregation
F6O44_RS16085	COG2186	Transcriptional regulator
F6O44_RS16090	COG0477	Major facilitator Superfamily
F6O44_RS16095	COG1609	Transcriptional regulator
F6O44_RS16100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6O44_RS16110	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6O44_RS16115	COG1129	ABC transporter
F6O44_RS16145	COG1522	sequence-specific DNA binding
F6O44_RS16150	COG0716	FMN binding
F6O44_RS16165	COG3312	ion transport
F6O44_RS16200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F6O44_RS16205	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F6O44_RS16215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F6O44_RS16230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F6O44_RS16235	COG0573	inorganic phosphate transmembrane transporter activity
F6O44_RS16240	COG0581	inorganic phosphate transmembrane transporter activity
F6O44_RS16250	COG0704	Plays a role in the regulation of phosphate uptake
F6O44_RS16265	COG2382	esterase
F6O44_RS16275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F6O44_RS16285	COG2252	PERMEase
F6O44_RS16290	COG0431	NADPH-dependent FMN reductase
F6O44_RS16320	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F6O44_RS16330	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F6O44_RS16350	COG0187	DNA topoisomerase II activity
F6O44_RS16355	COG0561	phosphatase activity
F6O44_RS16370	COG2186	Transcriptional regulator
F6O44_RS16375	COG3734	2-keto-3-deoxy-galactonokinase
F6O44_RS16380	COG0800	Aldolase
F6O44_RS16390	COG2271	Major facilitator Superfamily
F6O44_RS16395	COG0823	Involved in the tonB-independent uptake of proteins
F6O44_RS16400	COG5645	(Lipo)protein
F6O44_RS16420	COG2188	Transcriptional regulator
F6O44_RS16435	COG2149	membrane
F6O44_RS16455	COG2610	gluconate transmembrane transporter activity
F6O44_RS16460	COG0583	DNA-binding transcription factor activity
F6O44_RS16465	COG2814	Major facilitator Superfamily
F6O44_RS16490	COG0028	Belongs to the TPP enzyme family
F6O44_RS16495	COG0440	acetolactate synthase activity
F6O44_RS16500	COG2197	response regulator
F6O44_RS16510	COG2271	Major facilitator Superfamily
F6O44_RS16545	COG2188	Transcriptional regulator
F6O44_RS16570	COG4580	involved in the transport of maltose and maltodextrins
F6O44_RS16575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6O44_RS16575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6O44_RS16585	COG1609	Transcriptional regulator
F6O44_RS16595	COG0697	spore germination
F6O44_RS16645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6O44_RS16660	COG1263	PTS System
F6O44_RS16660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6O44_RS16670	COG1464	Belongs to the NlpA lipoprotein family
F6O44_RS16680	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F6O44_RS16690	COG1064	alcohol dehydrogenase
F6O44_RS16730	COG2211	Major facilitator Superfamily
F6O44_RS16735	COG1501	Belongs to the glycosyl hydrolase 31 family
F6O44_RS16745	COG1486	melibiose metabolic process
F6O44_RS16750	COG1263	PTS System
F6O44_RS16750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6O44_RS16755	COG2982	Protein involved in outer membrane biogenesis
F6O44_RS16760	COG2233	PERMEase
F6O44_RS16765	COG0786	glutamate:sodium symporter activity
F6O44_RS16780	COG3074	FtsZ-dependent cytokinesis
F6O44_RS16785	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F6O44_RS16810	COG3152	Membrane
F6O44_RS16820	COG1494	fructose-1,6-bisphosphatase
F6O44_RS16825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F6O44_RS16830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F6O44_RS16835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F6O44_RS16845	COG0194	GDP metabolic process
F6O44_RS16855	COG2194	sulfuric ester hydrolase activity
F6O44_RS16860	COG2860	membrane
F6O44_RS16865	COG1561	YicC-like family, N-terminal region
F6O44_RS16890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F6O44_RS16900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F6O44_RS16925	COG1519	Transferase
F6O44_RS16940	COG1216	Glycosyl transferase, family 2
F6O44_RS16955	COG0438	transferase activity, transferring glycosyl groups
F6O44_RS16960	COG0859	PFAM glycosyl transferase family 9
F6O44_RS16965	COG0859	PFAM glycosyl transferase family 9
F6O44_RS16980	COG0156	8-amino-7-oxononanoate synthase activity
F6O44_RS16995	COG0463	Glycosyl transferase, family 2
F6O44_RS17000	COG2861	carbohydrate metabolic process
F6O44_RS17005	COG4942	peptidase
F6O44_RS17015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F6O44_RS17020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F6O44_RS17040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F6O44_RS17050	COG2186	Transcriptional regulator
F6O44_RS17070	COG3722	fumarate hydratase activity
F6O44_RS17090	COG1566	PFAM secretion protein HlyD family protein
F6O44_RS17095	COG0625	glutathione transferase activity
F6O44_RS17105	COG3276	selenocysteine insertion sequence binding
F6O44_RS17110	COG1454	alcohol dehydrogenase
F6O44_RS17115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6O44_RS17120	COG3977	Valine--pyruvate aminotransferase
F6O44_RS17125	COG0366	Alpha amylase catalytic
F6O44_RS17130	COG2992	FlgJ-related protein
F6O44_RS17135	COG1609	Transcriptional regulator
F6O44_RS17135	COG2207	Transcriptional regulator
F6O44_RS17140	COG4214	carbohydrate transport
F6O44_RS17150	COG4213	ABC transporter substrate-binding protein
F6O44_RS17160	COG1070	Carbohydrate kinase
F6O44_RS17165	COG4682	membrane
F6O44_RS17170	COG3274	enterobacterial common antigen metabolic process
F6O44_RS17195	COG1278	Cold shock
F6O44_RS17200	COG2944	sequence-specific DNA binding
F6O44_RS17225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6O44_RS17235	COG1609	Transcriptional regulator
F6O44_RS17240	COG2885	chlorophyll binding
F6O44_RS17245	COG0243	molybdopterin cofactor binding
F6O44_RS17250	COG0456	acetyltransferase
F6O44_RS17255	COG2818	Glycosylase
F6O44_RS17260	COG5571	outer membrane autotransporter
F6O44_RS17265	COG2223	nitrite transmembrane transporter activity
F6O44_RS17290	COG0747	negative chemotaxis
F6O44_RS17295	COG0601	transmembrane transport
F6O44_RS17300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6O44_RS17305	COG0444	Belongs to the ABC transporter superfamily
F6O44_RS17310	COG4608	Belongs to the ABC transporter superfamily
F6O44_RS17325	COG2194	sulfuric ester hydrolase activity
F6O44_RS17355	COG1215	transferase activity, transferring glycosyl groups
F6O44_RS17360	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F6O44_RS17365	COG0457	Tetratricopeptide repeat
F6O44_RS17365	COG3118	belongs to the thioredoxin family
F6O44_RS17370	COG2199	diguanylate cyclase activity
F6O44_RS17370	COG2200	EAL domain
F6O44_RS17380	COG0612	Peptidase, M16
F6O44_RS17390	COG2982	Protein involved in outer membrane biogenesis
F6O44_RS17395	COG0477	Major facilitator Superfamily
F6O44_RS17400	COG1295	ribonuclease BN
F6O44_RS17405	COG0583	DNA-binding transcription factor activity
F6O44_RS17410	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS17415	COG2197	response regulator
F6O44_RS17425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F6O44_RS17435	COG1454	alcohol dehydrogenase
F6O44_RS17440	COG0625	glutathione transferase activity
F6O44_RS17445	COG1609	Transcriptional regulator
F6O44_RS17450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F6O44_RS17455	COG2610	gluconate transmembrane transporter activity
F6O44_RS17465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F6O44_RS17470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F6O44_RS17490	COG0589	response to stress
F6O44_RS17500	COG0306	phosphate transporter
F6O44_RS17505	COG2081	HI0933 family
F6O44_RS17510	COG2239	Acts as a magnesium transporter
F6O44_RS17530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6O44_RS17535	COG0601	transmembrane transport
F6O44_RS17540	COG0747	negative chemotaxis
F6O44_RS17550	COG3479	Phenolic acid decarboxylase
F6O44_RS17590	COG2091	lysine biosynthetic process via aminoadipic acid
F6O44_RS17595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F6O44_RS17600	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS17610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F6O44_RS17645	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F6O44_RS17645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F6O44_RS17655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F6O44_RS17675	COG0477	Major facilitator Superfamily
F6O44_RS17685	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F6O44_RS17700	COG3714	YhhN family
F6O44_RS17710	COG3776	membrane
F6O44_RS17715	COG0742	ribosomal rna small subunit methyltransferase
F6O44_RS17720	COG0552	protein localization to endoplasmic reticulum
F6O44_RS17725	COG2884	Cell division ATP-binding protein ftsE
F6O44_RS17730	COG2177	Part of the ABC transporter FtsEX involved in
F6O44_RS17740	COG0683	leucine binding
F6O44_RS17755	COG0683	leucine binding
F6O44_RS17760	COG0559	Belongs to the binding-protein-dependent transport system permease family
F6O44_RS17770	COG0411	ABC transporter
F6O44_RS17810	COG0584	glycerophosphoryl diester phosphodiesterase
F6O44_RS17820	COG0405	Gamma-glutamyltransferase
F6O44_RS17825	COG1247	-acetyltransferase
F6O44_RS17835	COG0673	inositol 2-dehydrogenase activity
F6O44_RS17840	COG1741	Belongs to the pirin family
F6O44_RS17845	COG1609	Transcriptional regulator
F6O44_RS17850	COG3265	gluconokinase activity
F6O44_RS17855	COG2610	gluconate transmembrane transporter activity
F6O44_RS17865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F6O44_RS17890	COG0058	SHG alpha-glucan phosphorylase activity
F6O44_RS17895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F6O44_RS17910	COG1349	DNA-binding transcription factor activity
F6O44_RS17920	COG0058	SHG alpha-glucan phosphorylase activity
F6O44_RS17925	COG1640	4-alpha-glucanotransferase
F6O44_RS17930	COG2610	gluconate transmembrane transporter activity
F6O44_RS17940	COG1040	competence protein
F6O44_RS17965	COG1918	ferrous iron import across plasma membrane
F6O44_RS17970	COG2183	response to ionizing radiation
F6O44_RS17975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F6O44_RS17985	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS17990	COG0179	Fumarylacetoacetate (FAA) hydrolase
F6O44_RS17995	COG4948	Mandelate Racemase Muconate Lactonizing
F6O44_RS18010	COG3254	rhamnose metabolic process
F6O44_RS18015	COG0738	Major facilitator superfamily
F6O44_RS18040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F6O44_RS18045	COG1011	Hydrolase
F6O44_RS18055	COG0494	nUDIX hydrolase
F6O44_RS18060	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F6O44_RS18085	COG4796	Type ii and iii secretion system protein
F6O44_RS18100	COG3266	domain, Protein
F6O44_RS18105	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F6O44_RS18110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F6O44_RS18130	COG2146	nitrite reductase [NAD(P)H] activity
F6O44_RS18135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F6O44_RS18145	COG0402	S-adenosylhomocysteine deaminase activity
F6O44_RS18150	COG0738	Major facilitator superfamily
F6O44_RS18165	COG2184	nucleotidyltransferase activity
F6O44_RS18175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F6O44_RS18180	COG1289	transmembrane transporter activity
F6O44_RS18190	COG1765	OsmC-like protein
F6O44_RS18195	COG3954	Phosphoribulokinase
F6O44_RS18205	COG0429	hydrolase of the alpha beta-hydrolase fold
F6O44_RS18215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F6O44_RS18225	COG0488	(ABC) transporter
F6O44_RS18240	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F6O44_RS18245	COG1047	Peptidyl-prolyl cis-trans
F6O44_RS18255	COG0545	Peptidyl-prolyl cis-trans isomerase
F6O44_RS18265	COG2964	Protein conserved in bacteria
F6O44_RS18325	COG0051	transcription antitermination factor activity, RNA binding
F6O44_RS18350	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F6O44_RS18365	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F6O44_RS18430	COG0201	protein transport
F6O44_RS18445	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F6O44_RS18470	COG0789	Transcriptional regulator
F6O44_RS18475	COG3036	rescue of stalled ribosome
F6O44_RS18505	COG0758	DNA mediated transformation
F6O44_RS18515	COG0551	DNA topoisomerase type I activity
F6O44_RS18535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F6O44_RS18580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6O44_RS18585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6O44_RS18590	COG1309	transcriptional regulator
F6O44_RS18610	COG4145	pantothenate transmembrane transporter activity
F6O44_RS18615	COG3924	membrane
F6O44_RS18620	COG0439	Biotin carboxylase
F6O44_RS18625	COG0511	ligase activity, forming carbon-carbon bonds
F6O44_RS18630	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F6O44_RS18645	COG0604	alcohol dehydrogenase
F6O44_RS18650	COG2200	EAL domain
F6O44_RS18650	COG2199	diguanylate cyclase activity
F6O44_RS18655	COG1077	Cell shape determining protein MreB Mrl
F6O44_RS18660	COG1792	Involved in formation and maintenance of cell shape
F6O44_RS18665	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F6O44_RS18680	COG3164	Protein of unknown function
F6O44_RS18690	COG0583	DNA-binding transcription factor activity
F6O44_RS18705	COG1289	transmembrane transporter activity
F6O44_RS18710	COG2732	(Barnase) inhibitor
F6O44_RS18735	COG1802	Transcriptional regulator
F6O44_RS18745	COG0471	metal ion transport
F6O44_RS18750	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F6O44_RS18755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F6O44_RS18785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F6O44_RS18790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F6O44_RS18795	COG3105	Protein conserved in bacteria
F6O44_RS18800	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F6O44_RS18815	COG0625	glutathione transferase activity
F6O44_RS18820	COG2969	positive regulation of protein catabolic process
F6O44_RS18825	COG0493	'glutamate synthase
F6O44_RS18830	COG0069	glutamate synthase activity
F6O44_RS18830	COG0067	glutamate synthase
F6O44_RS18830	COG0070	glutamate synthase
F6O44_RS18835	COG1242	4 iron, 4 sulfur cluster binding
F6O44_RS18840	COG5002	protein histidine kinase activity
F6O44_RS18840	COG2198	Histidine kinase
F6O44_RS18840	COG0784	Response regulator, receiver
F6O44_RS18845	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
F6O44_RS18850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F6O44_RS18855	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS18865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS18870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F6O44_RS18875	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F6O44_RS18880	COG1137	ATPase activity
F6O44_RS18885	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F6O44_RS18890	COG3117	lipopolysaccharide transmembrane transporter activity
F6O44_RS18895	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F6O44_RS18905	COG0530	calcium, potassium:sodium antiporter activity
F6O44_RS18915	COG1127	ABC transporter
F6O44_RS18920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F6O44_RS18925	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F6O44_RS18930	COG2854	intermembrane phospholipid transfer
F6O44_RS18935	COG3113	response to antibiotic
F6O44_RS18940	COG5007	Belongs to the BolA IbaG family
F6O44_RS18950	COG3423	Transcriptional regulator
F6O44_RS18955	COG0142	geranyltranstransferase activity
F6O44_RS18970	COG0697	spore germination
F6O44_RS18980	COG2027	D-alanyl-D-alanine carboxypeptidase
F6O44_RS18990	COG1534	Rna-binding protein
F6O44_RS19000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F6O44_RS19005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F6O44_RS19015	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F6O44_RS19055	COG0195	Participates in both transcription termination and antitermination
F6O44_RS19100	COG0814	amino acid
F6O44_RS19105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6O44_RS19110	COG0826	peptidase U32
F6O44_RS19115	COG0826	peptidase U32
F6O44_RS19120	COG3154	lipid carrier protein
F6O44_RS19125	COG3153	acetyltransferase
F6O44_RS19140	COG0693	protein deglycase activity
F6O44_RS19145	COG0702	epimerase
F6O44_RS19150	COG0701	Predicted permease
F6O44_RS19160	COG2823	Periplasmic or secreted lipoprotein
F6O44_RS19180	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F6O44_RS19190	COG1349	DNA-binding transcription factor activity
F6O44_RS19195	COG1063	alcohol dehydrogenase
F6O44_RS19205	COG3414	Phosphotransferase system galactitol-specific IIB component
F6O44_RS19210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS19220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS19220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS19225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS19225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6O44_RS19225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6O44_RS19230	COG1105	Belongs to the carbohydrate kinase PfkB family
F6O44_RS19240	COG1349	DNA-binding transcription factor activity
F6O44_RS19245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6O44_RS19250	COG2721	sulfolactate sulfo-lyase activity
F6O44_RS19260	COG2084	Dehydrogenase
F6O44_RS19265	COG1929	Belongs to the glycerate kinase type-1 family
F6O44_RS19290	COG1741	Belongs to the pirin family
F6O44_RS19295	COG0583	DNA-binding transcription factor activity
F6O44_RS19300	COG3152	Membrane
F6O44_RS19305	COG0435	Glutathione S-transferase
F6O44_RS19310	COG2259	Doxx family
F6O44_RS19325	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
F6O44_RS19330	COG4575	ribosome binding
F6O44_RS19335	COG1422	Protein of unknown function (DUF1090)
F6O44_RS19345	COG0586	Pfam SNARE associated Golgi protein
F6O44_RS19350	COG2186	Transcriptional regulator
F6O44_RS19355	COG2271	Major facilitator Superfamily
F6O44_RS19365	COG2721	sulfolactate sulfo-lyase activity
F6O44_RS19380	COG0673	inositol 2-dehydrogenase activity
F6O44_RS19385	COG1451	nucleotide metabolic process
F6O44_RS19395	COG0446	pyridine nucleotide-disulphide oxidoreductase
F6O44_RS19395	COG1902	pentaerythritol trinitrate reductase activity
F6O44_RS19440	COG3408	Glycogen debranching enzyme
F6O44_RS19440	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
F6O44_RS19450	COG0531	amino acid
F6O44_RS19455	COG0531	amino acid
F6O44_RS19460	COG2731	YhcH YjgK YiaL family protein
F6O44_RS19465	COG3250	beta-galactosidase activity
F6O44_RS19470	COG1609	Transcriptional regulator
F6O44_RS19475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F6O44_RS19485	COG1695	Transcriptional regulator
F6O44_RS19490	COG2375	cellular response to nickel ion
F6O44_RS19505	COG1461	Dihydroxyacetone kinase
F6O44_RS19510	COG2376	Dihydroxyacetone kinase
F6O44_RS19535	COG0641	radical SAM
F6O44_RS19570	COG0714	Associated with various cellular activities
F6O44_RS19575	COG0641	radical SAM
F6O44_RS19580	COG3119	arylsulfatase activity
F6O44_RS19640	COG3663	DNA glycosylase
F6O44_RS19650	COG0358	DNA primase activity
F6O44_RS19655	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F6O44_RS19665	COG0477	Major facilitator Superfamily
F6O44_RS19675	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F6O44_RS19690	COG4991	sh3 domain protein
F6O44_RS19695	COG3025	triphosphatase activity
F6O44_RS19715	COG2960	long-chain fatty acid transporting porin activity
F6O44_RS19725	COG3384	dioxygenase
F6O44_RS19730	COG0754	glutathionylspermidine amidase activity
F6O44_RS19745	COG0494	nUDIX hydrolase
F6O44_RS19750	COG3151	Protein conserved in bacteria
F6O44_RS19755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F6O44_RS19760	COG3150	esterase
F6O44_RS19765	COG0187	DNA topoisomerase II activity
F6O44_RS19770	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F6O44_RS19775	COG2249	NAD(P)H dehydrogenase (quinone) activity
F6O44_RS19780	COG0642	Histidine kinase
F6O44_RS19790	COG3111	PFAM Bacterial OB fold (BOF) protein
F6O44_RS19795	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F6O44_RS19805	COG0204	Acyl-transferase
F6O44_RS19815	COG1032	radical SAM domain protein
F6O44_RS19825	COG0656	L-ascorbic acid biosynthetic process
F6O44_RS19830	COG1979	alcohol dehydrogenase
F6O44_RS19835	COG2207	Transcriptional regulator
F6O44_RS19840	COG0586	Pfam SNARE associated Golgi protein
F6O44_RS19845	COG0626	cystathionine gamma-synthase activity
F6O44_RS19855	COG0848	biopolymer transport protein
F6O44_RS19865	COG0625	glutathione transferase activity
F6O44_RS19875	COG0754	glutathionylspermidine amidase activity
F6O44_RS19880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F6O44_RS19900	COG1012	belongs to the aldehyde dehydrogenase family
F6O44_RS19910	COG0583	DNA-binding transcription factor activity
F6O44_RS19920	COG2072	flavoprotein involved in K transport
F6O44_RS19935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F6O44_RS19940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F6O44_RS19950	COG0583	DNA-binding transcription factor activity
F6O44_RS19955	COG1652	LysM domain
F6O44_RS19960	COG3753	Protein conserved in bacteria
F6O44_RS19965	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F6O44_RS19970	COG1917	Cupin 2, conserved barrel domain protein
F6O44_RS19970	COG4977	sequence-specific DNA binding
F6O44_RS19985	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F6O44_RS20005	COG2382	esterase
F6O44_RS20025	COG2186	Transcriptional regulator
F6O44_RS20050	COG2731	YhcH YjgK YiaL family protein
F6O44_RS20075	COG1811	Na channel or pump
F6O44_RS20085	COG1982	Orn Lys Arg decarboxylase major
F6O44_RS20090	COG2211	Major facilitator Superfamily
F6O44_RS20105	COG1194	a g-specific adenine glycosylase
F6O44_RS20115	COG3171	Protein conserved in bacteria
F6O44_RS20125	COG4214	carbohydrate transport
F6O44_RS20140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F6O44_RS20155	COG0762	integral membrane protein
F6O44_RS20160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F6O44_RS20165	COG2805	Type II/IV secretion system protein
F6O44_RS20170	COG2197	response regulator
F6O44_RS20185	COG0189	ligase activity
F6O44_RS20190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F6O44_RS20195	COG2356	endonuclease I
F6O44_RS20205	COG2814	Major facilitator Superfamily
F6O44_RS20250	COG2146	nitrite reductase [NAD(P)H] activity
F6O44_RS20265	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS20270	COG1414	Transcriptional regulator
F6O44_RS20300	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS20305	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
F6O44_RS20325	COG0501	Belongs to the peptidase M48B family
F6O44_RS20330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F6O44_RS20345	COG0191	fructose-bisphosphate aldolase activity
F6O44_RS20350	COG0549	Belongs to the carbamate kinase family
F6O44_RS20355	COG2271	Major facilitator Superfamily
F6O44_RS20360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F6O44_RS20365	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F6O44_RS20375	COG0583	DNA-binding transcription factor activity
F6O44_RS20380	COG0668	transmembrane transport
F6O44_RS20385	COG1279	arginine transmembrane transporter activity
F6O44_RS20390	COG2968	Membrane
F6O44_RS20405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F6O44_RS20410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F6O44_RS20430	COG0006	proline dipeptidase activity
F6O44_RS20435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F6O44_RS20440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F6O44_RS20460	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS20465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F6O44_RS20485	COG2723	6-phospho-beta-galactosidase activity
F6O44_RS20490	COG1737	Transcriptional regulator
F6O44_RS20500	COG1272	protein, Hemolysin III
F6O44_RS20510	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F6O44_RS20520	COG0716	FMN binding
F6O44_RS20525	COG4974	Belongs to the 'phage' integrase family
F6O44_RS20535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F6O44_RS20555	COG4942	peptidase
F6O44_RS20580	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
F6O44_RS20590	COG1454	alcohol dehydrogenase
F6O44_RS20595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS20595	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS20620	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
F6O44_RS20625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F6O44_RS20635	COG1454	alcohol dehydrogenase
F6O44_RS20640	COG3933	PFAM sigma-54 factor interaction domain-containing protein
F6O44_RS20640	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F6O44_RS20655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F6O44_RS20685	COG3539	Fimbrial protein
F6O44_RS20695	COG3188	usher protein
F6O44_RS20700	COG3121	Chaperone
F6O44_RS20710	COG3539	Fimbrial protein
F6O44_RS20725	COG0124	histidyl-tRNA synthetase
F6O44_RS20740	COG0531	amino acid
F6O44_RS20750	COG0753	catalase activity
F6O44_RS20755	COG1609	Transcriptional regulator
F6O44_RS20760	COG0483	inositol monophosphate 1-phosphatase activity
F6O44_RS20765	COG2271	Major facilitator Superfamily
F6O44_RS20795	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F6O44_RS20810	COG0531	amino acid
F6O44_RS20815	COG1982	Orn Lys Arg decarboxylase major
F6O44_RS20830	COG1538	Outer membrane efflux protein
F6O44_RS20835	COG1289	transmembrane transporter activity
F6O44_RS20850	COG3592	Divergent 4Fe-4S mono-cluster
F6O44_RS20855	COG2388	GCN5-related N-acetyl-transferase
F6O44_RS20865	COG3539	Fimbrial protein
F6O44_RS20870	COG3539	Fimbrial protein
F6O44_RS20875	COG3539	Fimbrial protein
F6O44_RS20880	COG3188	usher protein
F6O44_RS20885	COG3121	Chaperone
F6O44_RS20890	COG3539	Fimbrial protein
F6O44_RS20905	COG4974	Belongs to the 'phage' integrase family
F6O44_RS20910	COG0582	viral genome integration into host DNA
F6O44_RS20935	COG3539	Fimbrial protein
F6O44_RS20945	COG3188	usher protein
F6O44_RS20960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F6O44_RS20970	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS20980	COG4638	Rieske (2fe-2S)
F6O44_RS20990	COG1960	acyl-CoA dehydrogenase activity
F6O44_RS20995	COG0154	amidase activity
F6O44_RS21005	COG1846	Transcriptional regulator
F6O44_RS21010	COG0697	spore germination
F6O44_RS21025	COG0640	Transcriptional regulator
F6O44_RS21040	COG0667	Aldo Keto reductase
F6O44_RS21045	COG0814	amino acid
F6O44_RS21055	COG0583	DNA-binding transcription factor activity
F6O44_RS21065	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS21070	COG2814	Major facilitator Superfamily
F6O44_RS21095	COG1794	racemase activity, acting on amino acids and derivatives
F6O44_RS21100	COG0583	DNA-binding transcription factor activity
F6O44_RS21110	COG1609	Transcriptional regulator
F6O44_RS21120	COG1609	Transcriptional regulator
F6O44_RS21135	COG0667	Aldo Keto reductase
F6O44_RS21145	COG0861	Integral membrane protein TerC family
F6O44_RS21185	COG2165	general secretion pathway protein
F6O44_RS21190	COG4795	General secretion pathway protein
F6O44_RS21210	COG1025	Belongs to the peptidase M16 family
F6O44_RS21215	COG1074	ATP-dependent DNA helicase activity
F6O44_RS21220	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F6O44_RS21225	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F6O44_RS21225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F6O44_RS21230	COG0860	N-Acetylmuramoyl-L-alanine amidase
F6O44_RS21250	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F6O44_RS21255	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F6O44_RS21260	COG2166	iron-sulfur cluster assembly
F6O44_RS21265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F6O44_RS21270	COG0583	DNA-binding transcription factor activity
F6O44_RS21275	COG2363	Small membrane protein
F6O44_RS21290	COG1760	l-serine dehydratase
F6O44_RS21295	COG0814	amino acid
F6O44_RS21300	COG1611	Belongs to the LOG family
F6O44_RS21315	COG3098	single-species biofilm formation
F6O44_RS21320	COG0564	pseudouridine synthase activity
F6O44_RS21325	COG0716	FMN binding
F6O44_RS21335	COG2271	Major facilitator Superfamily
F6O44_RS21340	COG4948	Mandelate Racemase Muconate Lactonizing
F6O44_RS21345	COG4948	Mandelate Racemase Muconate Lactonizing
F6O44_RS21350	COG1929	Belongs to the glycerate kinase type-1 family
F6O44_RS21355	COG3850	Histidine kinase
F6O44_RS21355	COG4999	Histidine kinase
F6O44_RS21355	COG3437	response regulator, receiver
F6O44_RS21355	COG2205	protein histidine kinase activity
F6O44_RS21365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F6O44_RS21370	COG3956	TIGRFAM MazG family protein
F6O44_RS21390	COG0602	queuosine metabolic process
F6O44_RS21395	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS21400	COG0720	synthase
F6O44_RS21425	COG2234	aminopeptidase activity
F6O44_RS21455	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F6O44_RS21485	COG4942	peptidase
F6O44_RS21485	COG1388	LysM domain
F6O44_RS21490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F6O44_RS21510	COG0163	prenyltransferase activity
F6O44_RS21515	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F6O44_RS21530	COG3121	Chaperone
F6O44_RS21565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6O44_RS21570	COG4558	Periplasmic binding protein
F6O44_RS21575	COG3720	iron ion transport
F6O44_RS21595	COG0679	Auxin Efflux Carrier
F6O44_RS21600	COG0583	DNA-binding transcription factor activity
F6O44_RS21610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F6O44_RS21615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F6O44_RS21620	COG1121	(ABC) transporter
F6O44_RS21635	COG0309	Hydrogenase expression formation protein (HypE)
F6O44_RS21640	COG0409	Hydrogenase expression formation protein
F6O44_RS21645	COG0298	carbon dioxide binding
F6O44_RS21650	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F6O44_RS21665	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6O44_RS21670	COG0651	ATP synthesis coupled electron transport
F6O44_RS21675	COG0650	Formate hydrogenlyase subunit 4
F6O44_RS21680	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
F6O44_RS21680	COG3261	NADH dehydrogenase
F6O44_RS21685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F6O44_RS21690	COG3260	NADH ubiquinone oxidoreductase 20
F6O44_RS21700	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F6O44_RS21705	COG2723	6-phospho-beta-galactosidase activity
F6O44_RS21710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6O44_RS21710	COG1263	PTS System
F6O44_RS21715	COG1609	Transcriptional regulator
F6O44_RS21720	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6O44_RS21725	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
F6O44_RS21730	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
F6O44_RS21755	COG1349	DNA-binding transcription factor activity
F6O44_RS21760	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS21765	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS21775	COG3732	PTS system glucitol sorbitol-specific
F6O44_RS21780	COG3730	PTS system glucitol sorbitol-specific
F6O44_RS21785	COG2951	lytic endotransglycosylase activity
F6O44_RS21800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F6O44_RS21805	COG0803	Belongs to the bacterial solute-binding protein 9 family
F6O44_RS21810	COG1546	Belongs to the CinA family
F6O44_RS21835	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
F6O44_RS21865	COG2823	Periplasmic or secreted lipoprotein
F6O44_RS21870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F6O44_RS21875	COG1238	metal cluster binding
F6O44_RS21895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F6O44_RS21900	COG2814	Major facilitator Superfamily
F6O44_RS21905	COG1566	PFAM secretion protein HlyD family protein
F6O44_RS21910	COG1846	Transcriptional regulator
F6O44_RS21920	COG4176	ABC-type proline glycine betaine transport system permease component
F6O44_RS21930	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F6O44_RS21935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F6O44_RS21945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F6O44_RS21950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F6O44_RS21960	COG4575	ribosome binding
F6O44_RS21995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F6O44_RS22000	COG0640	Transcriptional regulator
F6O44_RS22010	COG0583	DNA-binding transcription factor activity
F6O44_RS22015	COG0671	phosphoesterase, PA-phosphatase related
F6O44_RS22020	COG3284	Transcriptional regulator
F6O44_RS22030	COG4608	Belongs to the ABC transporter superfamily
F6O44_RS22035	COG0444	Belongs to the ABC transporter superfamily
F6O44_RS22040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6O44_RS22045	COG0601	transmembrane transport
F6O44_RS22050	COG0747	negative chemotaxis
F6O44_RS22055	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
F6O44_RS22085	COG1028	Short-chain dehydrogenase reductase Sdr
F6O44_RS22090	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
F6O44_RS22095	COG0583	DNA-binding transcription factor activity
F6O44_RS22100	COG0477	Major facilitator Superfamily
F6O44_RS22105	COG4133	protoheme IX ABC transporter activity
F6O44_RS22110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F6O44_RS22115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F6O44_RS22120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F6O44_RS22130	COG1138	Cytochrome C-type biogenesis protein
F6O44_RS22135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F6O44_RS22140	COG4235	cytochrome complex assembly
F6O44_RS22140	COG3088	subunit of a heme lyase
F6O44_RS22145	COG3088	subunit of a heme lyase
F6O44_RS22145	COG4235	cytochrome complex assembly
F6O44_RS22150	COG3005	denitrification pathway
F6O44_RS22155	COG0243	molybdopterin cofactor binding
F6O44_RS22165	COG3813	Protein conserved in bacteria
F6O44_RS22205	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F6O44_RS22235	COG2003	Belongs to the UPF0758 family
F6O44_RS22260	COG2378	regulation of single-species biofilm formation
F6O44_RS22270	COG2378	regulation of single-species biofilm formation
F6O44_RS22275	COG3596	GTP binding
F6O44_RS22300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F6O44_RS22310	COG3311	Transcriptional regulator
F6O44_RS22320	COG0582	viral genome integration into host DNA
F6O44_RS22335	COG2867	negative regulation of translational initiation
F6O44_RS22350	COG0497	DNA recombination
F6O44_RS22365	COG4536	flavin adenine dinucleotide binding
F6O44_RS22370	COG4137	Cytochrome C assembly protein
F6O44_RS22375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F6O44_RS22410	COG2885	chlorophyll binding
F6O44_RS22415	COG2199	diguanylate cyclase activity
F6O44_RS22425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F6O44_RS22430	COG1605	Chorismate mutase
F6O44_RS22430	COG0287	Prephenate dehydrogenase
F6O44_RS22440	COG1605	Chorismate mutase
F6O44_RS22440	COG0077	Prephenate dehydratase
F6O44_RS22450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F6O44_RS22455	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F6O44_RS22495	COG0477	Major facilitator Superfamily
F6O44_RS22500	COG5544	Lipoprotein
F6O44_RS22505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F6O44_RS22515	COG3148	PFAM DTW domain containing protein
F6O44_RS22520	COG3118	belongs to the thioredoxin family
F6O44_RS22525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F6O44_RS22540	COG0513	Belongs to the DEAD box helicase family
F6O44_RS22550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F6O44_RS22565	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
F6O44_RS22570	COG3026	antisigma factor binding
F6O44_RS22575	COG3086	response to oxidative stress
F6O44_RS22585	COG0681	Belongs to the peptidase S26 family
F6O44_RS22605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F6O44_RS22615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6O44_RS22620	COG1737	Transcriptional regulator
F6O44_RS22630	COG0560	Phosphoserine phosphatase
F6O44_RS22650	COG0047	phosphoribosylformylglycinamidine synthase activity
F6O44_RS22650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F6O44_RS22655	COG2205	protein histidine kinase activity
F6O44_RS22660	COG3170	Tfp pilus assembly protein FimV
F6O44_RS22665	COG2204	response regulator
F6O44_RS22670	COG0347	Belongs to the P(II) protein family
F6O44_RS22675	COG1017	nitric oxide dioxygenase activity
F6O44_RS22675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F6O44_RS22685	COG2259	Doxx family
F6O44_RS22695	COG3711	transcriptional antiterminator
F6O44_RS22700	COG3683	transport system, periplasmic component
F6O44_RS22705	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F6O44_RS22730	COG0822	iron-sulfur transferase activity
F6O44_RS22750	COG0633	Ferredoxin
F6O44_RS22755	COG2975	iron-sulfur cluster assembly
F6O44_RS22770	COG2897	thiosulfate sulfurtransferase activity
F6O44_RS22775	COG2373	Large extracellular alpha-helical protein
F6O44_RS22780	COG4953	penicillin-binding protein 1C
F6O44_RS22810	COG2976	Protein conserved in bacteria
F6O44_RS22825	COG1645	bacterial-type flagellum-dependent swarming motility
F6O44_RS22845	COG0517	IMP dehydrogenase activity
F6O44_RS22845	COG0516	GMP reductase activity
F6O44_RS22885	COG0248	Ppx GppA phosphatase
F6O44_RS22900	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F6O44_RS22905	COG2211	Major facilitator Superfamily
F6O44_RS22915	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F6O44_RS22930	COG2723	6-phospho-beta-galactosidase activity
F6O44_RS22940	COG2233	PERMEase
F6O44_RS22955	COG1393	Belongs to the ArsC family
F6O44_RS22960	COG4783	chaperone-mediated protein folding
F6O44_RS22965	COG0628	permease
F6O44_RS22970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F6O44_RS22975	COG2716	regulation of RNA biosynthetic process
F6O44_RS22985	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
F6O44_RS22995	COG2321	neutral zinc metallopeptidase
F6O44_RS23005	COG0400	carboxylic ester hydrolase activity
F6O44_RS23020	COG1393	Belongs to the ArsC family
F6O44_RS23030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6O44_RS23035	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6O44_RS23035	COG0493	'glutamate synthase
F6O44_RS23045	COG5342	invasion associated locus B
F6O44_RS23050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F6O44_RS23070	COG0860	N-Acetylmuramoyl-L-alanine amidase
F6O44_RS23090	COG2837	iron assimilation
F6O44_RS23095	COG4150	thiosulfate binding
F6O44_RS23100	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F6O44_RS23105	COG4208	sulfate ABC transporter
F6O44_RS23110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F6O44_RS23150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6O44_RS23175	COG3530	Putative quorum-sensing-regulated virulence factor
F6O44_RS23180	COG0385	Bile acid
F6O44_RS23185	COG0583	DNA-binding transcription factor activity
F6O44_RS23220	COG3415	Transposase
F6O44_RS23225	COG3415	Transposase
F6O44_RS23240	COG2200	EAL domain
F6O44_RS23240	COG2199	diguanylate cyclase activity
F6O44_RS23245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F6O44_RS23260	COG0667	Aldo Keto reductase
F6O44_RS23265	COG3961	Belongs to the TPP enzyme family
F6O44_RS23280	COG3279	Response regulator of the LytR AlgR family
F6O44_RS23285	COG3275	phosphorelay sensor kinase activity
F6O44_RS23290	COG0436	Aminotransferase
F6O44_RS23300	COG2807	transmembrane transport
F6O44_RS23305	COG0590	tRNA wobble adenosine to inosine editing
F6O44_RS23330	COG2116	formate transmembrane transporter activity
F6O44_RS23335	COG2853	Lipoprotein
F6O44_RS23345	COG3691	Protein conserved in bacteria
F6O44_RS23360	COG2062	phosphohistidine phosphatase, SixA
F6O44_RS23390	COG3101	peptidyl-lysine hydroxylation
F6O44_RS23405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F6O44_RS23410	COG2814	Major facilitator Superfamily
F6O44_RS23425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F6O44_RS23435	COG0586	Pfam SNARE associated Golgi protein
F6O44_RS23445	COG0285	dihydrofolate synthase activity
F6O44_RS23450	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
F6O44_RS23455	COG1286	toxin biosynthetic process
F6O44_RS23460	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F6O44_RS23465	COG0163	prenyltransferase activity
F6O44_RS23475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6O44_RS23490	COG4160	amino acid transport
F6O44_RS23495	COG4598	ABC transporter
F6O44_RS23515	COG1090	epimerase
F6O44_RS23520	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F6O44_RS23525	COG0625	glutathione transferase activity
F6O44_RS23530	COG0625	glutathione transferase activity
F6O44_RS23535	COG0622	Phosphoesterase
F6O44_RS23565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F6O44_RS23570	COG0471	metal ion transport
F6O44_RS23570	COG0490	domain, Protein
F6O44_RS23580	COG0436	Aminotransferase
F6O44_RS23585	COG0583	DNA-binding transcription factor activity
F6O44_RS23635	COG0839	Belongs to the complex I subunit 6 family
F6O44_RS23645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F6O44_RS23650	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F6O44_RS23665	COG2153	protein acetylation
F6O44_RS23670	COG1169	isochorismate synthase
F6O44_RS23695	COG0318	PFAM AMP-dependent synthetase and ligase
F6O44_RS23720	COG0642	Histidine kinase
F6O44_RS23740	COG0247	lactate metabolic process
F6O44_RS23750	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F6O44_RS23755	COG2271	Major facilitator Superfamily
F6O44_RS23760	COG0584	glycerophosphoryl diester phosphodiesterase
F6O44_RS23765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F6O44_RS23800	COG0642	Histidine kinase
F6O44_RS23800	COG2198	Histidine kinase
F6O44_RS23820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F6O44_RS23820	COG2169	Transcriptional regulator
F6O44_RS23830	COG4615	Cyclic peptide transporter
F6O44_RS23835	COG2239	Acts as a magnesium transporter
F6O44_RS23840	COG0659	secondary active sulfate transmembrane transporter activity
F6O44_RS23855	COG0628	permease
F6O44_RS23900	COG0494	nUDIX hydrolase
F6O44_RS23920	COG1061	Type III restriction enzyme res subunit
F6O44_RS23925	COG1187	pseudouridine synthase activity
F6O44_RS23930	COG2814	Major facilitator Superfamily
F6O44_RS23945	COG4172	Belongs to the ABC transporter superfamily
F6O44_RS23950	COG4239	(ABC) transporter, permease
F6O44_RS23955	COG4174	ABC transporter (Permease)
F6O44_RS23960	COG4166	transmembrane transport
F6O44_RS23965	COG2200	EAL domain
F6O44_RS23970	COG0791	NLP P60 protein
F6O44_RS23975	COG0671	phosphoesterase, PA-phosphatase related
F6O44_RS23980	COG0523	cobalamin synthesis protein
F6O44_RS23985	COG0246	Mannitol dehydrogenase
F6O44_RS23990	COG1312	Catalyzes the dehydration of D-mannonate
F6O44_RS24020	COG1105	Belongs to the carbohydrate kinase PfkB family
F6O44_RS24025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6O44_RS24025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6O44_RS24025	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F6O44_RS24035	COG2855	membrane
F6O44_RS24040	COG0583	DNA-binding transcription factor activity
F6O44_RS24055	COG0833	amino acid
F6O44_RS24060	COG4771	TonB-dependent receptor
F6O44_RS24065	COG1393	Belongs to the ArsC family
F6O44_RS24090	COG2311	Membrane
F6O44_RS24115	COG2949	membrane
F6O44_RS24125	COG1346	cytolysis
F6O44_RS24135	COG0583	DNA-binding transcription factor activity
F6O44_RS24140	COG2271	Major facilitator Superfamily
F6O44_RS24155	COG0625	glutathione transferase activity
F6O44_RS24160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F6O44_RS24165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F6O44_RS24180	COG2723	6-phospho-beta-galactosidase activity
F6O44_RS24195	COG0586	Pfam SNARE associated Golgi protein
F6O44_RS24205	COG1686	Belongs to the peptidase S11 family
F6O44_RS24215	COG0277	FAD linked oxidase domain protein
F6O44_RS24220	COG1472	Belongs to the glycosyl hydrolase 3 family
F6O44_RS24225	COG1732	Glycine betaine
F6O44_RS24230	COG1174	glycine betaine transport
F6O44_RS24235	COG1125	glycine betaine transport
F6O44_RS24240	COG1174	glycine betaine transport
F6O44_RS24250	COG0789	Transcriptional regulator
F6O44_RS24255	COG3275	phosphorelay sensor kinase activity
F6O44_RS24265	COG4807	Protein conserved in bacteria
F6O44_RS24270	COG4808	Protein conserved in bacteria
F6O44_RS24285	COG0489	protein tyrosine kinase activity
F6O44_RS24295	COG5455	response to cobalt ion
F6O44_RS24300	COG0583	DNA-binding transcription factor activity
F6O44_RS24305	COG2252	PERMEase
F6O44_RS24315	COG0583	DNA-binding transcription factor activity
F6O44_RS24325	COG2015	COG2015, Alkyl sulfatase and related hydrolases
F6O44_RS24335	COG2015	COG2015, Alkyl sulfatase and related hydrolases
F6O44_RS24365	COG1830	Aldolase
F6O44_RS24390	COG2390	Transcriptional regulator
F6O44_RS24400	COG1070	Carbohydrate kinase
F6O44_RS24415	COG0826	peptidase U32
F6O44_RS24420	COG0745	RESPONSE REGULATOR receiver
F6O44_RS24425	COG2205	protein histidine kinase activity
F6O44_RS24460	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F6O44_RS24475	COG2982	Protein involved in outer membrane biogenesis
F6O44_RS24480	COG1253	flavin adenine dinucleotide binding
F6O44_RS24620	COG2890	protein-(glutamine-N5) methyltransferase activity
F6O44_RS24680	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F6O44_RS24765	COG1192	Involved in chromosome partitioning
F6O44_RS25000	COG4245	von Willebrand factor, type A
F6O44_RS25005	COG4245	von Willebrand factor, type A
F6O44_RS25035	COG1358	cellular component organization or biogenesis
F6O44_RS25175	COG3550	peptidyl-serine autophosphorylation
F6O44_RS25200	COG0789	Transcriptional regulator
F6O44_RS25255	COG0789	Transcriptional regulator
F6O44_RS25465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F6O44_RS25470	COG1304	FMN binding
F6O44_RS25490	COG0484	heat shock protein binding
F6O44_RS25545	COG1662	PFAM IS1 transposase
F6O44_RS25550	COG1662	PFAM IS1 transposase
F6O44_RS25550	COG3677	Transposase
F6O44_RS25565	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F6O44_RS25565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F6O44_RS25585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F6O44_RS25600	COG3157	Type VI secretion system effector, Hcp
F6O44_RS25755	COG2026	Addiction module toxin, RelE StbE family
F6O44_RS25760	COG3077	Addiction module antitoxin, RelB DinJ family
F6O44_RS25770	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F6O44_RS25780	COG3547	Transposase (IS116 IS110 IS902 family)
F6O44_RS25785	COG2801	Transposase and inactivated derivatives
F6O44_RS25870	COG0583	DNA-binding transcription factor activity
F6O44_RS25895	COG3039	Transposase
F6O44_RS25915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F6O44_RS25940	COG2801	Transposase and inactivated derivatives
F6O44_RS25950	COG2801	Transposase and inactivated derivatives
F6O44_RS25955	COG0431	NADPH-dependent FMN reductase
F6O44_RS25960	COG0640	Transcriptional regulator
F6O44_RS25965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F6O44_RS25970	COG1393	Belongs to the ArsC family
F6O44_RS25975	COG0589	response to stress
F6O44_RS25980	COG0659	secondary active sulfate transmembrane transporter activity
F6O44_RS26070	COG2205	protein histidine kinase activity
F6O44_RS26080	COG2194	sulfuric ester hydrolase activity
F6O44_RS26130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F6O44_RS26220	COG1357	PFAM Pentapeptide repeats (8 copies)
F6O44_RS26330	COG1349	DNA-binding transcription factor activity
F6O44_RS26340	COG2084	Dehydrogenase