locus-tag	class	description
EAE_00010	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EAE_00030	COG3052	prosthetic group binding
EAE_00040	COG0179	Fumarylacetoacetate (FAA) hydrolase
EAE_00045	COG3493	citrate carrier protein
EAE_00060	COG2963	transposase activity
EAE_00070	COG2801	Transposase and inactivated derivatives
EAE_00075	COG3121	Chaperone
EAE_00085	COG3188	usher protein
EAE_00110	COG2963	transposase activity
EAE_00125	COG1733	regulation of RNA biosynthetic process
EAE_00160	COG3596	GTP binding
EAE_00190	COG2003	Belongs to the UPF0758 family
EAE_00240	COG0590	tRNA wobble adenosine to inosine editing
EAE_00245	COG2807	transmembrane transport
EAE_00250	COG0436	Aminotransferase
EAE_00255	COG3275	phosphorelay sensor kinase activity
EAE_00260	COG3279	Response regulator of the LytR AlgR family
EAE_00275	COG3961	Belongs to the TPP enzyme family
EAE_00280	COG0667	Aldo Keto reductase
EAE_00295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EAE_00300	COG2199	diguanylate cyclase activity
EAE_00300	COG2200	EAL domain
EAE_00310	COG3415	Transposase
EAE_00315	COG3415	Transposase
EAE_00330	COG0583	DNA-binding transcription factor activity
EAE_00335	COG0385	Bile acid
EAE_00340	COG3530	Putative quorum-sensing-regulated virulence factor
EAE_00365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE_00405	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EAE_00410	COG4208	sulfate ABC transporter
EAE_00415	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EAE_00420	COG4150	thiosulfate binding
EAE_00425	COG2837	iron assimilation
EAE_00445	COG0860	N-Acetylmuramoyl-L-alanine amidase
EAE_00465	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EAE_00470	COG5342	invasion associated locus B
EAE_00480	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAE_00480	COG0493	'glutamate synthase
EAE_00485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAE_00490	COG1393	Belongs to the ArsC family
EAE_00505	COG0400	carboxylic ester hydrolase activity
EAE_00515	COG2321	neutral zinc metallopeptidase
EAE_00525	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EAE_00535	COG2716	regulation of RNA biosynthetic process
EAE_00540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EAE_00545	COG0628	permease
EAE_00550	COG4783	chaperone-mediated protein folding
EAE_00555	COG1393	Belongs to the ArsC family
EAE_00570	COG2233	PERMEase
EAE_00580	COG2723	6-phospho-beta-galactosidase activity
EAE_00595	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EAE_00605	COG2211	Major facilitator Superfamily
EAE_00610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EAE_00625	COG0248	Ppx GppA phosphatase
EAE_00630	COG2200	EAL domain
EAE_00665	COG0517	IMP dehydrogenase activity
EAE_00665	COG0516	GMP reductase activity
EAE_00685	COG1645	bacterial-type flagellum-dependent swarming motility
EAE_00700	COG2976	Protein conserved in bacteria
EAE_00730	COG4953	penicillin-binding protein 1C
EAE_00735	COG2373	Large extracellular alpha-helical protein
EAE_00740	COG2897	thiosulfate sulfurtransferase activity
EAE_00755	COG2975	iron-sulfur cluster assembly
EAE_00760	COG0633	Ferredoxin
EAE_00780	COG0822	iron-sulfur transferase activity
EAE_00805	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EAE_00810	COG3683	transport system, periplasmic component
EAE_00815	COG3711	transcriptional antiterminator
EAE_00820	COG2814	Major facilitator Superfamily
EAE_00825	COG2259	Doxx family
EAE_00835	COG1017	nitric oxide dioxygenase activity
EAE_00835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE_00840	COG0347	Belongs to the P(II) protein family
EAE_00845	COG2204	response regulator
EAE_00850	COG3170	Tfp pilus assembly protein FimV
EAE_00855	COG2205	protein histidine kinase activity
EAE_00860	COG0047	phosphoribosylformylglycinamidine synthase activity
EAE_00860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAE_00880	COG0560	Phosphoserine phosphatase
EAE_00890	COG1737	Transcriptional regulator
EAE_00905	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAE_00915	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EAE_00935	COG0681	Belongs to the peptidase S26 family
EAE_00945	COG3086	response to oxidative stress
EAE_00950	COG3026	antisigma factor binding
EAE_00955	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EAE_00965	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EAE_00975	COG0513	Belongs to the DEAD box helicase family
EAE_00990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAE_00995	COG3118	belongs to the thioredoxin family
EAE_01000	COG3148	PFAM DTW domain containing protein
EAE_01010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAE_01015	COG5544	Lipoprotein
EAE_01020	COG0477	Major facilitator Superfamily
EAE_01025	COG0542	response to heat
EAE_01040	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAE_01045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EAE_01050	COG1605	Chorismate mutase
EAE_01050	COG0077	Prephenate dehydratase
EAE_01060	COG0287	Prephenate dehydrogenase
EAE_01060	COG1605	Chorismate mutase
EAE_01065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAE_01075	COG2199	diguanylate cyclase activity
EAE_01080	COG2885	chlorophyll binding
EAE_01115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EAE_01120	COG4137	Cytochrome C assembly protein
EAE_01125	COG4536	flavin adenine dinucleotide binding
EAE_01140	COG0497	DNA recombination
EAE_01155	COG2867	negative regulation of translational initiation
EAE_01175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EAE_01185	COG2169	Transcriptional regulator
EAE_01190	COG3813	Protein conserved in bacteria
EAE_01200	COG0243	molybdopterin cofactor binding
EAE_01205	COG3005	denitrification pathway
EAE_01210	COG4235	cytochrome complex assembly
EAE_01210	COG3088	subunit of a heme lyase
EAE_01215	COG4235	cytochrome complex assembly
EAE_01215	COG3088	subunit of a heme lyase
EAE_01220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EAE_01225	COG1138	Cytochrome C-type biogenesis protein
EAE_01235	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAE_01240	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAE_01245	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAE_01250	COG4133	protoheme IX ABC transporter activity
EAE_01255	COG0477	Major facilitator Superfamily
EAE_01260	COG0583	DNA-binding transcription factor activity
EAE_01265	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EAE_01280	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_01310	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EAE_01315	COG0747	negative chemotaxis
EAE_01320	COG0601	transmembrane transport
EAE_01325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAE_01330	COG0444	Belongs to the ABC transporter superfamily
EAE_01335	COG4608	Belongs to the ABC transporter superfamily
EAE_01345	COG3284	Transcriptional regulator
EAE_01350	COG0671	phosphoesterase, PA-phosphatase related
EAE_01355	COG0583	DNA-binding transcription factor activity
EAE_01365	COG0640	Transcriptional regulator
EAE_01370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAE_01400	COG4575	ribosome binding
EAE_01410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAE_01415	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAE_01425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAE_01430	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAE_01440	COG4176	ABC-type proline glycine betaine transport system permease component
EAE_01450	COG1846	Transcriptional regulator
EAE_01455	COG1566	PFAM secretion protein HlyD family protein
EAE_01460	COG2814	Major facilitator Superfamily
EAE_01465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAE_01485	COG1238	metal cluster binding
EAE_01490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAE_01495	COG2823	Periplasmic or secreted lipoprotein
EAE_01505	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EAE_01525	COG1546	Belongs to the CinA family
EAE_01530	COG0803	Belongs to the bacterial solute-binding protein 9 family
EAE_01535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EAE_01550	COG2951	lytic endotransglycosylase activity
EAE_01555	COG3730	PTS system glucitol sorbitol-specific
EAE_01560	COG3732	PTS system glucitol sorbitol-specific
EAE_01570	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_01575	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE_01580	COG1349	DNA-binding transcription factor activity
EAE_01605	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EAE_01610	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EAE_01615	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAE_01620	COG1609	Transcriptional regulator
EAE_01625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAE_01625	COG1263	PTS System
EAE_01630	COG2723	6-phospho-beta-galactosidase activity
EAE_01635	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EAE_01645	COG3260	NADH ubiquinone oxidoreductase 20
EAE_01650	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAE_01655	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EAE_01655	COG3261	NADH dehydrogenase
EAE_01660	COG0650	Formate hydrogenlyase subunit 4
EAE_01665	COG0651	ATP synthesis coupled electron transport
EAE_01670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAE_01685	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EAE_01690	COG0298	carbon dioxide binding
EAE_01695	COG0409	Hydrogenase expression formation protein
EAE_01700	COG0309	Hydrogenase expression formation protein (HypE)
EAE_01715	COG1121	(ABC) transporter
EAE_01720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EAE_01725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EAE_01735	COG0583	DNA-binding transcription factor activity
EAE_01740	COG0679	Auxin Efflux Carrier
EAE_01760	COG3720	iron ion transport
EAE_01765	COG4558	Periplasmic binding protein
EAE_01770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE_01805	COG3121	Chaperone
EAE_01820	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EAE_01825	COG0163	prenyltransferase activity
EAE_01845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EAE_01850	COG4942	peptidase
EAE_01850	COG1388	LysM domain
EAE_01880	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EAE_01910	COG2234	aminopeptidase activity
EAE_01930	COG0720	synthase
EAE_01935	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_01940	COG0602	queuosine metabolic process
EAE_01960	COG3956	TIGRFAM MazG family protein
EAE_01965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAE_01975	COG4999	Histidine kinase
EAE_01975	COG3850	Histidine kinase
EAE_01975	COG3437	response regulator, receiver
EAE_01975	COG2205	protein histidine kinase activity
EAE_01980	COG1929	Belongs to the glycerate kinase type-1 family
EAE_01985	COG4948	Mandelate Racemase Muconate Lactonizing
EAE_01990	COG4948	Mandelate Racemase Muconate Lactonizing
EAE_01995	COG2271	Major facilitator Superfamily
EAE_02005	COG0716	FMN binding
EAE_02010	COG0564	pseudouridine synthase activity
EAE_02015	COG3098	single-species biofilm formation
EAE_02030	COG1611	Belongs to the LOG family
EAE_02035	COG0814	amino acid
EAE_02040	COG1760	l-serine dehydratase
EAE_02055	COG2363	Small membrane protein
EAE_02060	COG0583	DNA-binding transcription factor activity
EAE_02065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EAE_02070	COG2166	iron-sulfur cluster assembly
EAE_02075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EAE_02080	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EAE_02085	COG0860	N-Acetylmuramoyl-L-alanine amidase
EAE_02090	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EAE_02090	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EAE_02095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EAE_02100	COG1074	ATP-dependent DNA helicase activity
EAE_02105	COG1025	Belongs to the peptidase M16 family
EAE_02110	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EAE_02125	COG4795	General secretion pathway protein
EAE_02130	COG2165	general secretion pathway protein
EAE_02160	COG0861	Integral membrane protein TerC family
EAE_02170	COG0667	Aldo Keto reductase
EAE_02185	COG1609	Transcriptional regulator
EAE_02195	COG1609	Transcriptional regulator
EAE_02205	COG0583	DNA-binding transcription factor activity
EAE_02210	COG1794	racemase activity, acting on amino acids and derivatives
EAE_02235	COG2814	Major facilitator Superfamily
EAE_02240	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_02245	COG0183	Belongs to the thiolase family
EAE_02250	COG0583	DNA-binding transcription factor activity
EAE_02260	COG0814	amino acid
EAE_02265	COG0667	Aldo Keto reductase
EAE_02280	COG0640	Transcriptional regulator
EAE_02295	COG0697	spore germination
EAE_02300	COG1846	Transcriptional regulator
EAE_02310	COG0154	amidase activity
EAE_02315	COG1960	acyl-CoA dehydrogenase activity
EAE_02325	COG4638	Rieske (2fe-2S)
EAE_02335	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_02345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAE_02360	COG3188	usher protein
EAE_02365	COG3121	Chaperone
EAE_02370	COG3539	Fimbrial protein
EAE_02395	COG0582	viral genome integration into host DNA
EAE_02400	COG4974	Belongs to the 'phage' integrase family
EAE_02415	COG3539	Fimbrial protein
EAE_02420	COG3121	Chaperone
EAE_02425	COG3188	usher protein
EAE_02430	COG3539	Fimbrial protein
EAE_02435	COG3539	Fimbrial protein
EAE_02440	COG3539	Fimbrial protein
EAE_02450	COG2388	GCN5-related N-acetyl-transferase
EAE_02455	COG3592	Divergent 4Fe-4S mono-cluster
EAE_02470	COG1289	transmembrane transporter activity
EAE_02475	COG1538	Outer membrane efflux protein
EAE_02485	COG1982	Orn Lys Arg decarboxylase major
EAE_02490	COG0531	amino acid
EAE_02505	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EAE_02530	COG2271	Major facilitator Superfamily
EAE_02535	COG0483	inositol monophosphate 1-phosphatase activity
EAE_02540	COG1609	Transcriptional regulator
EAE_02545	COG0753	catalase activity
EAE_02555	COG0531	amino acid
EAE_02565	COG0124	histidyl-tRNA synthetase
EAE_02570	COG0124	histidyl-tRNA synthetase
EAE_02585	COG3539	Fimbrial protein
EAE_02595	COG3121	Chaperone
EAE_02600	COG3188	usher protein
EAE_02610	COG3539	Fimbrial protein
EAE_02640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EAE_02660	COG2003	Belongs to the UPF0758 family
EAE_02695	COG3596	GTP binding
EAE_02735	COG2963	transposase activity
EAE_02750	COG3188	usher protein
EAE_02760	COG0583	DNA-binding transcription factor activity
EAE_02770	COG2200	EAL domain
EAE_02770	COG2771	luxR family
EAE_02780	COG0582	viral genome integration into host DNA
EAE_02785	COG4942	peptidase
EAE_02805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EAE_02815	COG4974	Belongs to the 'phage' integrase family
EAE_02820	COG0716	FMN binding
EAE_02830	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EAE_02840	COG1272	protein, Hemolysin III
EAE_02850	COG1737	Transcriptional regulator
EAE_02855	COG2723	6-phospho-beta-galactosidase activity
EAE_02875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EAE_02880	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_02900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAE_02905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAE_02910	COG0006	proline dipeptidase activity
EAE_02925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EAE_02930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAE_02945	COG2968	Membrane
EAE_02950	COG1279	arginine transmembrane transporter activity
EAE_02955	COG0668	transmembrane transport
EAE_02960	COG0191	fructose-bisphosphate aldolase activity
EAE_02975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EAE_02980	COG0501	Belongs to the peptidase M48B family
EAE_03000	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
EAE_03005	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_03035	COG1414	Transcriptional regulator
EAE_03040	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_03055	COG2146	nitrite reductase [NAD(P)H] activity
EAE_03095	COG2814	Major facilitator Superfamily
EAE_03105	COG2356	endonuclease I
EAE_03110	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EAE_03115	COG0189	ligase activity
EAE_03130	COG2197	response regulator
EAE_03135	COG2805	Type II/IV secretion system protein
EAE_03140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EAE_03145	COG0762	integral membrane protein
EAE_03160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EAE_03175	COG4214	carbohydrate transport
EAE_03185	COG3171	Protein conserved in bacteria
EAE_03195	COG1194	a g-specific adenine glycosylase
EAE_03210	COG2211	Major facilitator Superfamily
EAE_03215	COG1982	Orn Lys Arg decarboxylase major
EAE_03220	COG1811	Na channel or pump
EAE_03235	COG2731	YhcH YjgK YiaL family protein
EAE_03260	COG2186	Transcriptional regulator
EAE_03280	COG2382	esterase
EAE_03290	COG4771	TonB-dependent receptor
EAE_03300	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EAE_03315	COG4977	sequence-specific DNA binding
EAE_03315	COG1917	Cupin 2, conserved barrel domain protein
EAE_03320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EAE_03325	COG3753	Protein conserved in bacteria
EAE_03330	COG1652	LysM domain
EAE_03345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EAE_03350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EAE_03365	COG2072	flavoprotein involved in K transport
EAE_03375	COG0583	DNA-binding transcription factor activity
EAE_03385	COG1012	belongs to the aldehyde dehydrogenase family
EAE_03400	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EAE_03405	COG1012	belongs to the aldehyde dehydrogenase family
EAE_03410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAE_03415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAE_03420	COG2267	carboxylic ester hydrolase activity
EAE_03430	COG1802	Transcriptional regulator
EAE_03445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAE_03450	COG0754	glutathionylspermidine amidase activity
EAE_03460	COG0625	glutathione transferase activity
EAE_03470	COG0848	biopolymer transport protein
EAE_03480	COG0626	cystathionine gamma-synthase activity
EAE_03485	COG0586	Pfam SNARE associated Golgi protein
EAE_03490	COG2207	Transcriptional regulator
EAE_03500	COG1979	alcohol dehydrogenase
EAE_03505	COG0656	L-ascorbic acid biosynthetic process
EAE_03515	COG1032	radical SAM domain protein
EAE_03525	COG0204	Acyl-transferase
EAE_03535	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EAE_03540	COG3111	PFAM Bacterial OB fold (BOF) protein
EAE_03560	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAE_03565	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EAE_03570	COG0187	DNA topoisomerase II activity
EAE_03575	COG3150	esterase
EAE_03580	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EAE_03585	COG3151	Protein conserved in bacteria
EAE_03590	COG0494	nUDIX hydrolase
EAE_03605	COG0754	glutathionylspermidine amidase activity
EAE_03610	COG3384	dioxygenase
EAE_03620	COG2960	long-chain fatty acid transporting porin activity
EAE_03640	COG3025	triphosphatase activity
EAE_03645	COG4991	sh3 domain protein
EAE_03660	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EAE_03670	COG0477	Major facilitator Superfamily
EAE_03680	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EAE_03685	COG0358	DNA primase activity
EAE_03695	COG3663	DNA glycosylase
EAE_03700	COG3385	transposase activity
EAE_03735	COG2801	Transposase and inactivated derivatives
EAE_03780	COG3119	arylsulfatase activity
EAE_03785	COG0641	radical SAM
EAE_03790	COG0714	Associated with various cellular activities
EAE_03825	COG0641	radical SAM
EAE_03850	COG2376	Dihydroxyacetone kinase
EAE_03855	COG1461	Dihydroxyacetone kinase
EAE_03870	COG2375	cellular response to nickel ion
EAE_03875	COG1695	Transcriptional regulator
EAE_03885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAE_03890	COG1609	Transcriptional regulator
EAE_03895	COG3250	beta-galactosidase activity
EAE_03900	COG2731	YhcH YjgK YiaL family protein
EAE_03905	COG0531	amino acid
EAE_03910	COG0531	amino acid
EAE_03920	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EAE_03920	COG3408	Glycogen debranching enzyme
EAE_03965	COG1902	pentaerythritol trinitrate reductase activity
EAE_03965	COG0446	pyridine nucleotide-disulphide oxidoreductase
EAE_03975	COG1451	nucleotide metabolic process
EAE_03980	COG0673	inositol 2-dehydrogenase activity
EAE_03995	COG2721	sulfolactate sulfo-lyase activity
EAE_04005	COG2271	Major facilitator Superfamily
EAE_04010	COG2186	Transcriptional regulator
EAE_04015	COG0586	Pfam SNARE associated Golgi protein
EAE_04025	COG1422	Protein of unknown function (DUF1090)
EAE_04030	COG4575	ribosome binding
EAE_04035	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EAE_04050	COG2259	Doxx family
EAE_04055	COG0435	Glutathione S-transferase
EAE_04060	COG3152	Membrane
EAE_04065	COG0583	DNA-binding transcription factor activity
EAE_04070	COG1741	Belongs to the pirin family
EAE_04085	COG0668	transmembrane transport
EAE_04090	COG1929	Belongs to the glycerate kinase type-1 family
EAE_04095	COG2084	Dehydrogenase
EAE_04105	COG2721	sulfolactate sulfo-lyase activity
EAE_04110	COG1349	DNA-binding transcription factor activity
EAE_04120	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAE_04130	COG3716	PTS system mannose fructose sorbose family IID component
EAE_04140	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE_04145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EAE_04150	COG2222	sugar isomerase
EAE_04165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EAE_04185	COG2823	Periplasmic or secreted lipoprotein
EAE_04190	COG0701	Predicted permease
EAE_04195	COG0702	epimerase
EAE_04200	COG0693	protein deglycase activity
EAE_04215	COG3153	acetyltransferase
EAE_04220	COG3154	lipid carrier protein
EAE_04225	COG0826	peptidase U32
EAE_04230	COG0826	peptidase U32
EAE_04235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAE_04240	COG0814	amino acid
EAE_04280	COG0195	Participates in both transcription termination and antitermination
EAE_04310	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EAE_04320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EAE_04325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAE_04335	COG1534	Rna-binding protein
EAE_04345	COG2027	D-alanyl-D-alanine carboxypeptidase
EAE_04355	COG0697	spore germination
EAE_04370	COG0142	geranyltranstransferase activity
EAE_04375	COG3423	Transcriptional regulator
EAE_04385	COG5007	Belongs to the BolA IbaG family
EAE_04390	COG3113	response to antibiotic
EAE_04395	COG2854	intermembrane phospholipid transfer
EAE_04400	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EAE_04405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EAE_04410	COG1127	ABC transporter
EAE_04415	COG0530	calcium, potassium:sodium antiporter activity
EAE_04425	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EAE_04430	COG3117	lipopolysaccharide transmembrane transporter activity
EAE_04435	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EAE_04440	COG1137	ATPase activity
EAE_04445	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EAE_04450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EAE_04455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE_04465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE_04470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAE_04475	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EAE_04480	COG0784	Response regulator, receiver
EAE_04480	COG2198	Histidine kinase
EAE_04480	COG5002	protein histidine kinase activity
EAE_04485	COG1242	4 iron, 4 sulfur cluster binding
EAE_04490	COG0070	glutamate synthase
EAE_04490	COG0069	glutamate synthase activity
EAE_04490	COG0067	glutamate synthase
EAE_04495	COG0493	'glutamate synthase
EAE_04500	COG2969	positive regulation of protein catabolic process
EAE_04505	COG0625	glutathione transferase activity
EAE_04520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EAE_04525	COG3105	Protein conserved in bacteria
EAE_04530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAE_04535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAE_04565	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EAE_04570	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EAE_04575	COG0471	metal ion transport
EAE_04585	COG1802	Transcriptional regulator
EAE_04610	COG2732	(Barnase) inhibitor
EAE_04615	COG1289	transmembrane transporter activity
EAE_04630	COG0583	DNA-binding transcription factor activity
EAE_04635	COG0312	modulator of DNA gyrase
EAE_04640	COG3164	Protein of unknown function
EAE_04655	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EAE_04660	COG1792	Involved in formation and maintenance of cell shape
EAE_04665	COG1077	Cell shape determining protein MreB Mrl
EAE_04670	COG2200	EAL domain
EAE_04670	COG2199	diguanylate cyclase activity
EAE_04675	COG0604	alcohol dehydrogenase
EAE_04690	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EAE_04695	COG0511	ligase activity, forming carbon-carbon bonds
EAE_04700	COG0439	Biotin carboxylase
EAE_04705	COG3924	membrane
EAE_04710	COG4145	pantothenate transmembrane transporter activity
EAE_04730	COG1309	transcriptional regulator
EAE_04735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE_04740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAE_04750	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAE_04770	COG0551	DNA topoisomerase type I activity
EAE_04780	COG0758	DNA mediated transformation
EAE_04810	COG3036	rescue of stalled ribosome
EAE_04815	COG0789	Transcriptional regulator
EAE_04840	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EAE_04855	COG0201	protein transport
EAE_04920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EAE_04935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EAE_04960	COG0051	transcription antitermination factor activity, RNA binding
EAE_05015	COG2964	Protein conserved in bacteria
EAE_05020	COG0545	Peptidyl-prolyl cis-trans isomerase
EAE_05030	COG1047	Peptidyl-prolyl cis-trans
EAE_05035	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EAE_05050	COG0488	(ABC) transporter
EAE_05055	COG0429	hydrolase of the alpha beta-hydrolase fold
EAE_05065	COG3954	Phosphoribulokinase
EAE_05070	COG1765	OsmC-like protein
EAE_05080	COG1289	transmembrane transporter activity
EAE_05085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EAE_05095	COG2184	nucleotidyltransferase activity
EAE_05110	COG0738	Major facilitator superfamily
EAE_05115	COG0402	S-adenosylhomocysteine deaminase activity
EAE_05120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAE_05125	COG2146	nitrite reductase [NAD(P)H] activity
EAE_05145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EAE_05150	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EAE_05155	COG3266	domain, Protein
EAE_05170	COG4796	Type ii and iii secretion system protein
EAE_05195	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EAE_05210	COG0494	nUDIX hydrolase
EAE_05220	COG1011	Hydrolase
EAE_05225	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EAE_05250	COG0738	Major facilitator superfamily
EAE_05255	COG3254	rhamnose metabolic process
EAE_05260	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_05270	COG4948	Mandelate Racemase Muconate Lactonizing
EAE_05275	COG0179	Fumarylacetoacetate (FAA) hydrolase
EAE_05280	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_05285	COG2186	Transcriptional regulator
EAE_05290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAE_05295	COG2183	response to ionizing radiation
EAE_05300	COG1918	ferrous iron import across plasma membrane
EAE_05325	COG1040	competence protein
EAE_05335	COG2610	gluconate transmembrane transporter activity
EAE_05340	COG1640	4-alpha-glucanotransferase
EAE_05345	COG0058	SHG alpha-glucan phosphorylase activity
EAE_05355	COG1349	DNA-binding transcription factor activity
EAE_05370	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EAE_05375	COG0058	SHG alpha-glucan phosphorylase activity
EAE_05400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EAE_05405	COG2610	gluconate transmembrane transporter activity
EAE_05410	COG3265	gluconokinase activity
EAE_05415	COG1609	Transcriptional regulator
EAE_05420	COG1741	Belongs to the pirin family
EAE_05425	COG0673	inositol 2-dehydrogenase activity
EAE_05440	COG1247	-acetyltransferase
EAE_05445	COG0405	Gamma-glutamyltransferase
EAE_05455	COG0584	glycerophosphoryl diester phosphodiesterase
EAE_05485	COG0411	ABC transporter
EAE_05495	COG0559	Belongs to the binding-protein-dependent transport system permease family
EAE_05500	COG0683	leucine binding
EAE_05515	COG0683	leucine binding
EAE_05525	COG2177	Part of the ABC transporter FtsEX involved in
EAE_05530	COG2884	Cell division ATP-binding protein ftsE
EAE_05535	COG0552	protein localization to endoplasmic reticulum
EAE_05540	COG0742	ribosomal rna small subunit methyltransferase
EAE_05545	COG3776	membrane
EAE_05555	COG3714	YhhN family
EAE_05570	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EAE_05580	COG0477	Major facilitator Superfamily
EAE_05600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAE_05610	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EAE_05610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAE_05645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAE_05655	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_05660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAE_05665	COG2091	lysine biosynthetic process via aminoadipic acid
EAE_05705	COG3479	Phenolic acid decarboxylase
EAE_05715	COG0747	negative chemotaxis
EAE_05720	COG0601	transmembrane transport
EAE_05725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAE_05755	COG2239	Acts as a magnesium transporter
EAE_05760	COG2081	HI0933 family
EAE_05765	COG0306	phosphate transporter
EAE_05775	COG0589	response to stress
EAE_05785	COG1959	2 iron, 2 sulfur cluster binding
EAE_05805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EAE_05810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAE_05820	COG2610	gluconate transmembrane transporter activity
EAE_05825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EAE_05830	COG1609	Transcriptional regulator
EAE_05835	COG0625	glutathione transferase activity
EAE_05840	COG1454	alcohol dehydrogenase
EAE_05850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAE_05860	COG2197	response regulator
EAE_05865	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_05870	COG0583	DNA-binding transcription factor activity
EAE_05875	COG1295	ribonuclease BN
EAE_05880	COG0477	Major facilitator Superfamily
EAE_05885	COG2982	Protein involved in outer membrane biogenesis
EAE_05895	COG0612	Peptidase, M16
EAE_05905	COG2199	diguanylate cyclase activity
EAE_05905	COG2200	EAL domain
EAE_05910	COG0457	Tetratricopeptide repeat
EAE_05910	COG3118	belongs to the thioredoxin family
EAE_05915	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EAE_05920	COG1215	transferase activity, transferring glycosyl groups
EAE_05950	COG2194	sulfuric ester hydrolase activity
EAE_05970	COG4608	Belongs to the ABC transporter superfamily
EAE_05975	COG0444	Belongs to the ABC transporter superfamily
EAE_05980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAE_05985	COG0601	transmembrane transport
EAE_06010	COG2223	nitrite transmembrane transporter activity
EAE_06015	COG5571	outer membrane autotransporter
EAE_06020	COG2818	Glycosylase
EAE_06025	COG0456	acetyltransferase
EAE_06030	COG0243	molybdopterin cofactor binding
EAE_06035	COG2885	chlorophyll binding
EAE_06040	COG1609	Transcriptional regulator
EAE_06050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAE_06070	COG2814	Major facilitator Superfamily
EAE_06075	COG2944	sequence-specific DNA binding
EAE_06080	COG1278	Cold shock
EAE_06105	COG3274	enterobacterial common antigen metabolic process
EAE_06110	COG4682	membrane
EAE_06115	COG1070	Carbohydrate kinase
EAE_06130	COG4213	ABC transporter substrate-binding protein
EAE_06140	COG4214	carbohydrate transport
EAE_06145	COG2207	Transcriptional regulator
EAE_06145	COG1609	Transcriptional regulator
EAE_06150	COG2992	FlgJ-related protein
EAE_06155	COG0366	Alpha amylase catalytic
EAE_06160	COG3977	Valine--pyruvate aminotransferase
EAE_06165	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAE_06170	COG1454	alcohol dehydrogenase
EAE_06175	COG3276	selenocysteine insertion sequence binding
EAE_06185	COG0625	glutathione transferase activity
EAE_06190	COG1566	PFAM secretion protein HlyD family protein
EAE_06210	COG3722	fumarate hydratase activity
EAE_06230	COG2186	Transcriptional regulator
EAE_06240	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EAE_06260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAE_06265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAE_06275	COG4942	peptidase
EAE_06280	COG2861	carbohydrate metabolic process
EAE_06285	COG0463	Glycosyl transferase, family 2
EAE_06300	COG0156	8-amino-7-oxononanoate synthase activity
EAE_06315	COG0859	PFAM glycosyl transferase family 9
EAE_06340	COG0859	PFAM glycosyl transferase family 9
EAE_06355	COG1216	Glycosyl transferase, family 2
EAE_06360	COG1519	Transferase
EAE_06385	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EAE_06395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EAE_06420	COG1561	YicC-like family, N-terminal region
EAE_06425	COG2860	membrane
EAE_06435	COG0194	GDP metabolic process
EAE_06445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAE_06450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAE_06455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EAE_06460	COG1494	fructose-1,6-bisphosphatase
EAE_06470	COG3152	Membrane
EAE_06495	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EAE_06500	COG3074	FtsZ-dependent cytokinesis
EAE_06515	COG0786	glutamate:sodium symporter activity
EAE_06520	COG2233	PERMEase
EAE_06525	COG2982	Protein involved in outer membrane biogenesis
EAE_06530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAE_06530	COG1263	PTS System
EAE_06535	COG1486	melibiose metabolic process
EAE_06545	COG1501	Belongs to the glycosyl hydrolase 31 family
EAE_06550	COG2211	Major facilitator Superfamily
EAE_06555	COG0582	viral genome integration into host DNA
EAE_06605	COG3596	GTP binding
EAE_06610	COG2378	regulation of single-species biofilm formation
EAE_06625	COG2003	Belongs to the UPF0758 family
EAE_06675	COG1064	alcohol dehydrogenase
EAE_06685	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EAE_06695	COG1464	Belongs to the NlpA lipoprotein family
EAE_06705	COG1263	PTS System
EAE_06705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAE_06720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAE_06780	COG0697	spore germination
EAE_06790	COG1609	Transcriptional regulator
EAE_06800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAE_06800	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAE_06805	COG4580	involved in the transport of maltose and maltodextrins
EAE_06830	COG2188	Transcriptional regulator
EAE_06870	COG2271	Major facilitator Superfamily
EAE_06880	COG2197	response regulator
EAE_06885	COG0440	acetolactate synthase activity
EAE_06890	COG0028	Belongs to the TPP enzyme family
EAE_06905	COG2814	Major facilitator Superfamily
EAE_06910	COG0583	DNA-binding transcription factor activity
EAE_06915	COG2610	gluconate transmembrane transporter activity
EAE_06935	COG2149	membrane
EAE_06950	COG2188	Transcriptional regulator
EAE_06970	COG5645	(Lipo)protein
EAE_06975	COG0823	Involved in the tonB-independent uptake of proteins
EAE_06980	COG2271	Major facilitator Superfamily
EAE_06990	COG0800	Aldolase
EAE_06995	COG3734	2-keto-3-deoxy-galactonokinase
EAE_07000	COG2186	Transcriptional regulator
EAE_07015	COG0561	phosphatase activity
EAE_07020	COG0187	DNA topoisomerase II activity
EAE_07030	COG0592	DNA-directed DNA polymerase activity
EAE_07040	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EAE_07050	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EAE_07080	COG2091	lysine biosynthetic process via aminoadipic acid
EAE_07085	COG0431	NADPH-dependent FMN reductase
EAE_07090	COG2252	PERMEase
EAE_07095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAE_07100	COG0363	glucosamine-6-phosphate deaminase activity
EAE_07105	COG2382	esterase
EAE_07120	COG0704	Plays a role in the regulation of phosphate uptake
EAE_07130	COG0581	inorganic phosphate transmembrane transporter activity
EAE_07135	COG0573	inorganic phosphate transmembrane transporter activity
EAE_07140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EAE_07150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EAE_07160	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EAE_07165	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EAE_07200	COG3312	ion transport
EAE_07215	COG0716	FMN binding
EAE_07220	COG1522	sequence-specific DNA binding
EAE_07250	COG1129	ABC transporter
EAE_07255	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAE_07265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAE_07270	COG1609	Transcriptional regulator
EAE_07275	COG0477	Major facilitator Superfamily
EAE_07280	COG2186	Transcriptional regulator
EAE_07285	COG1763	Mo-molybdopterin cofactor biosynthetic process
EAE_07295	COG3084	Protein conserved in bacteria
EAE_07300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAE_07310	COG0204	Acyl-transferase
EAE_07335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EAE_07345	COG3852	Histidine kinase
EAE_07360	COG2188	Transcriptional regulator
EAE_07365	COG1082	Xylose isomerase domain protein TIM barrel
EAE_07370	COG2271	Major facilitator Superfamily
EAE_07375	COG1011	Hydrolase
EAE_07390	COG0456	acetyltransferase
EAE_07395	COG0657	acetylesterase activity
EAE_07405	COG2864	formate dehydrogenase
EAE_07410	COG0437	4 iron, 4 sulfur cluster binding
EAE_07415	COG3383	formate dehydrogenase (NAD+) activity
EAE_07415	COG0243	molybdopterin cofactor binding
EAE_07420	COG0243	molybdopterin cofactor binding
EAE_07420	COG3383	formate dehydrogenase (NAD+) activity
EAE_07440	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EAE_07450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAE_07455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAE_07460	COG2731	YhcH YjgK YiaL family protein
EAE_07465	COG2271	Major facilitator Superfamily
EAE_07475	COG1454	alcohol dehydrogenase
EAE_07515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EAE_07520	COG2258	MOSC domain
EAE_07525	COG2205	protein histidine kinase activity
EAE_07530	COG0745	RESPONSE REGULATOR receiver
EAE_07535	COG3678	ATP-independent chaperone mediated protein folding
EAE_07555	COG1575	Belongs to the MenA family. Type 1 subfamily
EAE_07570	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EAE_07575	COG1609	Transcriptional regulator
EAE_07580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EAE_07595	COG0626	cystathionine gamma-synthase activity
EAE_07600	COG0527	aspartate kinase activity
EAE_07600	COG0460	homoserine dehydrogenase
EAE_07610	COG0697	spore germination
EAE_07615	COG0371	Dehydrogenase
EAE_07625	COG2207	Transcriptional regulator
EAE_07630	COG3443	Belongs to the bacterial solute-binding protein 9 family
EAE_07645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EAE_07660	COG0583	DNA-binding transcription factor activity
EAE_07700	COG3085	chromosome segregation
EAE_07705	COG0606	chelatase, subunit chli
EAE_07715	COG3978	acetolactate synthase activity
EAE_07720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EAE_07730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAE_07735	COG0583	DNA-binding transcription factor activity
EAE_07745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAE_07750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAE_07760	COG1811	Na channel or pump
EAE_07770	COG0583	DNA-binding transcription factor activity
EAE_07785	COG3118	belongs to the thioredoxin family
EAE_07790	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EAE_07795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EAE_07805	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EAE_07810	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EAE_07815	COG0456	acetyltransferase
EAE_07820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EAE_07825	COG2244	polysaccharide biosynthetic process
EAE_07850	COG3071	HemY protein
EAE_07855	COG2959	enzyme of heme biosynthesis
EAE_07860	COG1587	Uroporphyrinogen-III synthase
EAE_07870	COG3072	Adenylate cyclase
EAE_07905	COG1011	Hydrolase
EAE_07910	COG0210	DNA helicase
EAE_07925	COG2050	protein possibly involved in aromatic compounds catabolism
EAE_07940	COG1280	lysine exporter protein (LysE YggA)
EAE_07950	COG1280	lysine exporter protein (LysE YggA)
EAE_07955	COG2267	carboxylic ester hydrolase activity
EAE_07960	COG0561	phosphatase activity
EAE_07965	COG0697	spore germination
EAE_07970	COG0583	DNA-binding transcription factor activity
EAE_08000	COG3165	ubiquinone biosynthetic process from chorismate
EAE_08010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EAE_08020	COG0805	protein transport
EAE_08060	COG1739	Uncharacterized protein family UPF0029
EAE_08070	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EAE_08100	COG0250	Participates in transcription elongation, termination and antitermination
EAE_08135	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EAE_08140	COG1447	Phosphotransferase system cellobiose-specific component IIA
EAE_08150	COG3706	GGDEF domain
EAE_08165	COG2104	thiamine diphosphate biosynthetic process
EAE_08170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EAE_08185	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EAE_08225	COG4191	Histidine kinase
EAE_08235	COG0151	Belongs to the GarS family
EAE_08255	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EAE_08275	COG0646	methionine synthase
EAE_08275	COG1410	methionine synthase
EAE_08280	COG1283	sodium-dependent phosphate transmembrane transporter activity
EAE_08295	COG1187	pseudouridine synthase activity
EAE_08320	COG4650	regulator
EAE_08330	COG1690	Belongs to the RtcB family
EAE_08335	COG3541	Predicted nucleotidyltransferase
EAE_08340	COG0527	aspartate kinase activity
EAE_08350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EAE_08355	COG0251	oxidation-reduction process
EAE_08400	COG4580	involved in the transport of maltose and maltodextrins
EAE_08425	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EAE_08435	COG0534	Mate efflux family protein
EAE_08440	COG3237	CsbD-like
EAE_08445	COG0735	belongs to the Fur family
EAE_08455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAE_08470	COG0305	Participates in initiation and elongation during chromosome replication
EAE_08475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EAE_08480	COG1448	Aminotransferase
EAE_08490	COG0432	Pfam Uncharacterised protein family UPF0047
EAE_08495	COG2315	Protein conserved in bacteria
EAE_08510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EAE_08535	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EAE_08550	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EAE_08560	COG0789	Transcriptional regulator
EAE_08565	COG0625	glutathione transferase activity
EAE_08570	COG2252	PERMEase
EAE_08575	COG0025	NhaP-type Na H and K H
EAE_08580	COG0583	DNA-binding transcription factor activity
EAE_08590	COG1346	cytolysis
EAE_08595	COG3539	Fimbrial protein
EAE_08610	COG3539	Fimbrial protein
EAE_08615	COG3539	Fimbrial protein
EAE_08625	COG3162	membrane
EAE_08630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAE_08635	COG1301	dicarboxylic acid transport
EAE_08640	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EAE_08665	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAE_08670	COG1129	ABC transporter
EAE_08675	COG0784	Response regulator, receiver
EAE_08675	COG4191	Histidine kinase
EAE_08685	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EAE_08695	COG3454	Phosphonate metabolism
EAE_08700	COG4778	phosphonate C-P lyase system protein PhnL
EAE_08705	COG4107	phosphonate C-P lyase system protein PhnK
EAE_08710	COG3627	carbon phosphorus lyase activity
EAE_08715	COG3626	phosphonate metabolism
EAE_08720	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EAE_08725	COG3624	Phosphonate C-P lyase system protein PhnG
EAE_08730	COG2188	Transcriptional regulator
EAE_08735	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EAE_08740	COG2824	Alkylphosphonate utilization operon protein PhnA
EAE_08755	COG2169	Transcriptional regulator
EAE_08760	COG1486	melibiose metabolic process
EAE_08795	COG0861	Integral membrane protein TerC family
EAE_08810	COG1215	transferase activity, transferring glycosyl groups
EAE_08815	COG1649	PFAM Uncharacterised BCR, COG1649
EAE_08815	COG0726	polysaccharide deacetylase
EAE_08820	COG0457	Tetratricopeptide repeat
EAE_08875	COG1216	Glycosyl transferase, family 2
EAE_08875	COG1442	glycosyl transferase family 8
EAE_08925	COG2135	peptidase activity
EAE_08935	COG2135	peptidase activity
EAE_08945	COG2207	Transcriptional regulator
EAE_08965	COG2826	transposase and inactivated derivatives, IS30 family
EAE_08970	COG3547	Transposase (IS116 IS110 IS902 family)
EAE_09005	COG3210	domain, Protein
EAE_09085	COG0582	viral genome integration into host DNA
EAE_09095	COG1309	transcriptional regulator
EAE_09110	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EAE_09115	COG1027	Aspartate ammonia-lyase
EAE_09120	COG3030	protein affecting phage T7 exclusion by the F plasmid
EAE_09125	COG0531	amino acid
EAE_09135	COG0459	protein refolding
EAE_09195	COG1509	lysine 2,3-aminomutase activity
EAE_09210	COG5510	response to toxic substance
EAE_09215	COG2076	Multidrug Resistance protein
EAE_09235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EAE_09240	COG1053	succinate dehydrogenase
EAE_09255	COG3264	Mechanosensitive ion channel
EAE_09255	COG1511	domain protein
EAE_09275	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EAE_09280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE_09285	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EAE_09290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EAE_09290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EAE_09295	COG0802	atpase or kinase
EAE_09300	COG0860	N-Acetylmuramoyl-L-alanine amidase
EAE_09320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EAE_09325	COG0330	HflC and HflK could
EAE_09330	COG0330	HflC and HflK could
EAE_09340	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EAE_09355	COG0557	exoribonuclease II activity
EAE_09360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAE_09365	COG0477	Major facilitator Superfamily
EAE_09370	COG1960	acyl-CoA dehydrogenase activity
EAE_09380	COG3650	response to hydrogen peroxide
EAE_09385	COG1073	alpha beta
EAE_09445	COG2965	DNA replication, synthesis of RNA primer
EAE_09450	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EAE_09455	COG0359	binds to the 23S rRNA
EAE_09465	COG3061	Opacity-associated protein A
EAE_09470	COG0545	Peptidyl-prolyl cis-trans isomerase
EAE_09475	COG1113	amino acid transport
EAE_09485	COG0697	spore germination
EAE_09495	COG0702	epimerase
EAE_09500	COG1733	regulation of RNA biosynthetic process
EAE_09505	COG1733	regulation of RNA biosynthetic process
EAE_09520	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EAE_09530	COG1253	flavin adenine dinucleotide binding
EAE_09540	COG0729	surface antigen
EAE_09545	COG2911	Protein conserved in bacteria
EAE_09550	COG2105	PFAM AIG2 family protein
EAE_09560	COG1879	ABC-type sugar transport system periplasmic component
EAE_09565	COG1129	ABC transporter
EAE_09570	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAE_09575	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAE_09585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EAE_09600	COG0312	modulator of DNA gyrase
EAE_09635	COG3964	amidohydrolase
EAE_09650	COG2706	6-phosphogluconolactonase activity
EAE_09655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE_09655	COG3711	transcriptional antiterminator
EAE_09660	COG0602	queuosine metabolic process
EAE_09680	COG1486	melibiose metabolic process
EAE_09685	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAE_09690	COG0366	Alpha amylase catalytic
EAE_09695	COG1263	PTS System
EAE_09695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAE_09700	COG1609	Transcriptional regulator
EAE_09710	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EAE_09715	COG0251	oxidation-reduction process
EAE_09730	COG2731	YhcH YjgK YiaL family protein
EAE_09735	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EAE_09755	COG0525	valine-tRNA ligase activity
EAE_09760	COG2927	DNA polymerase III (CHI subunit)
EAE_09770	COG0795	lipopolysaccharide-transporting ATPase activity
EAE_09775	COG0795	lipopolysaccharide-transporting ATPase activity
EAE_09785	COG0433	COG0433 Predicted ATPase
EAE_09800	COG3718	enzyme involved in inositol metabolism
EAE_09805	COG1737	Transcriptional regulator
EAE_09805	COG0837	glucose binding
EAE_09810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAE_09815	COG3962	Belongs to the TPP enzyme family
EAE_09825	COG1082	Xylose isomerase domain protein TIM barrel
EAE_09835	COG2814	Major facilitator Superfamily
EAE_09845	COG3842	ATPase activity
EAE_09850	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EAE_09855	COG0395	ABC-type sugar transport system, permease component
EAE_09860	COG1175	transmembrane transport
EAE_09865	COG1064	alcohol dehydrogenase
EAE_09870	COG0659	secondary active sulfate transmembrane transporter activity
EAE_09875	COG0288	reversible hydration of carbon dioxide
EAE_09930	COG1401	restriction endodeoxyribonuclease activity
EAE_09945	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EAE_09970	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAE_09975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE_09980	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE_09985	COG1538	Outer membrane efflux protein
EAE_09990	COG0745	RESPONSE REGULATOR receiver
EAE_09995	COG5002	protein histidine kinase activity
EAE_10000	COG2850	peptidyl-arginine hydroxylation
EAE_10015	COG0842	Transport permease protein
EAE_10020	COG1129	ABC transporter
EAE_10020	COG0842	Transport permease protein
EAE_10025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE_10030	COG3706	GGDEF domain
EAE_10055	COG4869	propanediol catabolic process
EAE_10065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAE_10070	COG1882	Formate acetyltransferase
EAE_10085	COG1454	alcohol dehydrogenase
EAE_10085	COG1012	belongs to the aldehyde dehydrogenase family
EAE_10130	COG3716	PTS system mannose fructose sorbose family IID component
EAE_10135	COG3715	PTS system
EAE_10140	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE_10140	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAE_10160	COG0531	amino acid
EAE_10170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAE_10175	COG5457	Domain of unknown function (DUF1127)
EAE_10185	COG1566	PFAM secretion protein HlyD family protein
EAE_10195	COG3366	ferrous iron transmembrane transporter activity
EAE_10200	COG0700	Nucleoside recognition
EAE_10205	COG1473	amidohydrolase
EAE_10215	COG1924	4 iron, 4 sulfur cluster binding
EAE_10220	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
EAE_10235	COG2733	membrane
EAE_10240	COG1012	belongs to the aldehyde dehydrogenase family
EAE_10245	COG0523	cobalamin synthesis protein
EAE_10250	COG2879	small protein
EAE_10255	COG1966	Carbon starvation protein
EAE_10260	COG2831	hemolysin activation secretion protein
EAE_10265	COG3210	domain, Protein
EAE_10300	COG3210	domain, Protein
EAE_10310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAE_10315	COG2368	4-hydroxyphenylacetate
EAE_10335	COG3971	2-oxopent-4-enoate hydratase activity
EAE_10345	COG3384	dioxygenase
EAE_10350	COG1012	belongs to the aldehyde dehydrogenase family
EAE_10360	COG0179	Fumarylacetoacetate (FAA) hydrolase
EAE_10365	COG1846	Transcriptional regulator
EAE_10380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAE_10380	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EAE_10395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAE_10400	COG1012	belongs to the aldehyde dehydrogenase family
EAE_10405	COG0531	amino acid
EAE_10420	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EAE_10435	COG3734	2-keto-3-deoxy-galactonokinase
EAE_10440	COG0800	Aldolase
EAE_10445	COG0837	glucose binding
EAE_10445	COG1737	Transcriptional regulator
EAE_10470	COG1484	DNA-dependent DNA replication
EAE_10485	COG2966	Psort location CytoplasmicMembrane, score
EAE_10500	COG2197	response regulator
EAE_10505	COG2197	response regulator
EAE_10510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAE_10515	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAE_10520	COG4114	ferric iron reductase
EAE_10525	COG3706	GGDEF domain
EAE_10540	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EAE_10545	COG0456	acetyltransferase
EAE_10550	COG1011	Hydrolase
EAE_10560	COG2823	Periplasmic or secreted lipoprotein
EAE_10565	COG5487	UPF0391 membrane protein
EAE_10570	COG4667	esterase of the alpha-beta hydrolase superfamily
EAE_10575	COG0084	hydrolase, TatD family'
EAE_10605	COG3726	membrane protein affecting hemolysin expression
EAE_10610	COG0560	Phosphoserine phosphatase
EAE_10615	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EAE_10625	COG0488	(ABC) transporter
EAE_10630	COG0741	lytic transglycosylase activity
EAE_10650	COG2207	Transcriptional regulator
EAE_10650	COG3708	Transcriptional regulator
EAE_10655	COG3045	CreA protein
EAE_10660	COG0745	RESPONSE REGULATOR receiver
EAE_10665	COG2205	protein histidine kinase activity
EAE_10670	COG4452	Inner membrane protein CreD
EAE_10675	COG0745	RESPONSE REGULATOR receiver
EAE_10680	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EAE_10685	COG0460	homoserine dehydrogenase
EAE_10685	COG0527	aspartate kinase activity
EAE_10695	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EAE_10705	COG1115	amino acid carrier protein
EAE_10710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EAE_10715	COG0521	Mo-molybdopterin cofactor biosynthetic process
EAE_10725	COG1584	GPR1 FUN34 yaaH family protein
EAE_10740	COG0583	DNA-binding transcription factor activity
EAE_10775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAE_10780	COG3539	Fimbrial protein
EAE_10790	COG3188	usher protein
EAE_10805	COG3539	Fimbrial protein
EAE_10810	COG3121	Chaperone
EAE_10830	COG0583	DNA-binding transcription factor activity
EAE_10840	COG0196	riboflavin kinase activity
EAE_10850	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EAE_10855	COG1047	Peptidyl-prolyl cis-trans
EAE_10870	COG0583	DNA-binding transcription factor activity
EAE_10880	COG2828	Protein conserved in bacteria
EAE_10885	COG0471	metal ion transport
EAE_10890	COG0471	metal ion transport
EAE_10895	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EAE_10905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EAE_10980	COG0505	Belongs to the CarA family
EAE_11030	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EAE_11040	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EAE_11045	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EAE_11060	COG3493	citrate carrier protein
EAE_11070	COG0564	pseudouridine synthase activity
EAE_11080	COG0417	DNA replication proofreading
EAE_11085	COG0235	Class ii aldolase
EAE_11105	COG0586	Pfam SNARE associated Golgi protein
EAE_11115	COG1178	ABC-type Fe3 transport system permease component
EAE_11135	COG2814	Major facilitator Superfamily
EAE_11140	COG2271	Major facilitator Superfamily
EAE_11145	COG0583	DNA-binding transcription factor activity
EAE_11155	COG0738	Major facilitator superfamily
EAE_11200	COG0028	Belongs to the TPP enzyme family
EAE_11230	COG0768	penicillin binding
EAE_11235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAE_11240	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EAE_11255	COG0772	Belongs to the SEDS family
EAE_11270	COG1181	Belongs to the D-alanine--D-alanine ligase family
EAE_11280	COG0849	cell division
EAE_11285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EAE_11305	COG0494	nUDIX hydrolase
EAE_11330	COG1459	type II secretion system
EAE_11335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAE_11340	COG4969	Belongs to the N-Me-Phe pilin family
EAE_11355	COG3725	Membrane protein required for beta-lactamase induction
EAE_11360	COG3940	Belongs to the glycosyl hydrolase 43 family
EAE_11365	COG2211	Major facilitator Superfamily
EAE_11370	COG1113	amino acid transport
EAE_11375	COG2186	Transcriptional regulator
EAE_11380	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EAE_11385	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAE_11390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAE_11405	COG3064	Membrane
EAE_11410	COG1049	propionate catabolic process, 2-methylcitrate cycle
EAE_11430	COG0545	Peptidyl-prolyl cis-trans isomerase
EAE_11445	COG2132	Multicopper oxidase
EAE_11450	COG4993	Dehydrogenase
EAE_11460	COG0288	reversible hydration of carbon dioxide
EAE_11465	COG1131	(ABC) transporter
EAE_11470	COG0842	Transport permease protein
EAE_11475	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE_11480	COG0726	polysaccharide deacetylase
EAE_11485	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EAE_11500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EAE_11525	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EAE_11530	COG1643	Atp-dependent helicase
EAE_11545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAE_11550	COG4774	siderophore transport
EAE_11555	COG1120	ATPase activity
EAE_11560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EAE_11565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE_11585	COG2860	membrane
EAE_11610	COG3835	regulator
EAE_11630	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EAE_11635	COG0024	Methionine aminopeptidase
EAE_11660	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EAE_11670	COG0575	Belongs to the CDS family
EAE_11675	COG0750	zinc metalloprotease
EAE_11730	COG1982	Orn Lys Arg decarboxylase major
EAE_11735	COG0346	lactoylglutathione lyase activity
EAE_11740	COG0037	tRNA processing
EAE_11745	COG4568	rho-dependent transcription termination
EAE_11755	COG4681	YaeQ
EAE_11760	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EAE_11765	COG3015	lipoprotein NlpE involved in copper resistance
EAE_11775	COG1720	tRNA m6t6A37 methyltransferase activity
EAE_11785	COG1464	Belongs to the NlpA lipoprotein family
EAE_11790	COG2011	ABC-type metal ion transport system permease component
EAE_11800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EAE_11805	COG0656	L-ascorbic acid biosynthetic process
EAE_11810	COG0583	DNA-binding transcription factor activity
EAE_11815	COG2814	Major facilitator Superfamily
EAE_11825	COG2226	methyltransferase
EAE_11830	COG1388	LysM domain
EAE_11830	COG0741	lytic transglycosylase activity
EAE_11840	COG2226	methyltransferase
EAE_11850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAE_11855	COG0583	DNA-binding transcription factor activity
EAE_11865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAE_11870	COG1960	acyl-CoA dehydrogenase activity
EAE_11880	COG0121	glutamine amidotransferase
EAE_11885	COG3034	peptidoglycan biosynthetic process
EAE_11900	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EAE_11905	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EAE_11920	COG2991	Protein conserved in bacteria
EAE_11935	COG0454	-acetyltransferase
EAE_11945	COG2195	Cleaves the N-terminal amino acid of tripeptides
EAE_11965	COG1045	serine acetyltransferase
EAE_11980	COG0438	transferase activity, transferring glycosyl groups
EAE_11980	COG0297	glycogen (starch) synthase activity
EAE_11985	COG0438	transferase activity, transferring glycosyl groups
EAE_11990	COG0463	Glycosyl transferase, family 2
EAE_12010	COG1596	polysaccharide export
EAE_12020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EAE_12035	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_12045	COG0583	DNA-binding transcription factor activity
EAE_12060	COG1802	Transcriptional regulator
EAE_12065	COG1113	amino acid transport
EAE_12070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAE_12075	COG1012	belongs to the aldehyde dehydrogenase family
EAE_12080	COG0579	oxidoreductase
EAE_12100	COG3188	usher protein
EAE_12105	COG3121	Chaperone
EAE_12165	COG0791	NLP P60 protein
EAE_12185	COG3639	organic phosphonate transmembrane transporter activity
EAE_12195	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EAE_12220	COG3188	usher protein
EAE_12240	COG2271	Major facilitator Superfamily
EAE_12245	COG0583	DNA-binding transcription factor activity
EAE_12250	COG0765	amino acid transport
EAE_12255	COG0765	amino acid transport
EAE_12265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE_12275	COG0833	amino acid
EAE_12280	COG2040	homocysteine
EAE_12285	COG4521	taurine ABC transporter
EAE_12290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EAE_12295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAE_12300	COG2175	clavaminate synthase activity
EAE_12315	COG1943	Transposase
EAE_12320	COG0113	porphobilinogen synthase activity
EAE_12325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EAE_12335	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EAE_12355	COG1181	Belongs to the D-alanine--D-alanine ligase family
EAE_12370	COG1785	Belongs to the alkaline phosphatase family
EAE_12380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EAE_12390	COG3416	Protein conserved in bacteria
EAE_12395	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EAE_12405	COG4126	flavin adenine dinucleotide binding
EAE_12420	COG1940	carbohydrate kinase activity
EAE_12425	COG0419	ATPase involved in DNA repair
EAE_12430	COG0420	3'-5' exonuclease activity
EAE_12455	COG0366	Alpha amylase catalytic
EAE_12460	COG0583	DNA-binding transcription factor activity
EAE_12465	COG1335	isochorismatase
EAE_12475	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EAE_12480	COG0450	alkyl hydroperoxide reductase
EAE_12500	COG1862	Preprotein translocase
EAE_12510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAE_12525	COG3248	Nucleoside-binding outer membrane protein
EAE_12530	COG4238	major outer membrane lipoprotein
EAE_12540	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAE_12540	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAE_12555	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EAE_12560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EAE_12565	COG0667	Aldo Keto reductase
EAE_12575	COG0142	geranyltranstransferase activity
EAE_12600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EAE_12615	COG2831	hemolysin activation secretion protein
EAE_12620	COG0736	holo-[acyl-carrier-protein] synthase activity
EAE_12625	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_12630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EAE_12645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAE_12660	COG1136	(ABC) transporter
EAE_12700	COG2814	Major facilitator Superfamily
EAE_12715	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EAE_12720	COG1845	cytochrome c oxidase, subunit III
EAE_12725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EAE_12730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EAE_12735	COG2223	nitrite transmembrane transporter activity
EAE_12740	COG3056	Lipoprotein
EAE_12750	COG0271	Belongs to the BolA IbaG family
EAE_12775	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EAE_12780	COG0776	regulation of translation
EAE_12785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAE_12795	COG1555	photosystem II stabilization
EAE_12800	COG0824	Thioesterase
EAE_12810	COG4533	DNA binding
EAE_12825	COG1522	sequence-specific DNA binding
EAE_12830	COG1132	(ABC) transporter
EAE_12835	COG1132	(ABC) transporter
EAE_12840	COG0347	Belongs to the P(II) protein family
EAE_12845	COG0004	ammonium transporteR
EAE_12850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EAE_12855	COG0583	DNA-binding transcription factor activity
EAE_12860	COG1946	Acyl-CoA thioesterase
EAE_12865	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EAE_12870	COG3695	enzyme binding
EAE_12895	COG2364	Membrane
EAE_12900	COG5507	3-demethylubiquinone-9 3-methyltransferase
EAE_12905	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EAE_12915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EAE_12935	COG0110	maltose O-acetyltransferase activity
EAE_12950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAE_12955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE_12960	COG1309	transcriptional regulator
EAE_12965	COG3264	Mechanosensitive ion channel
EAE_12965	COG1196	nuclear chromosome segregation
EAE_12975	COG3923	Primosomal replication protein n
EAE_12980	COG2832	Protein of unknown function (DUF454)
EAE_13020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAE_13025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAE_13025	COG4651	solute:proton antiporter activity
EAE_13030	COG2223	nitrite transmembrane transporter activity
EAE_13040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAE_13045	COG3735	TraB family
EAE_13060	COG1585	Membrane protein implicated in regulation of membrane protease activity
EAE_13065	COG0330	HflC and HflK could
EAE_13070	COG4619	ABC transporter
EAE_13075	COG0390	transport system, permease component
EAE_13080	COG3118	belongs to the thioredoxin family
EAE_13085	COG0300	oxidoreductase activity
EAE_13090	COG2755	lipolytic protein G-D-S-L family
EAE_13095	COG4181	ATPase activity
EAE_13100	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EAE_13115	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EAE_13120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EAE_13130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EAE_13140	COG2501	S4 domain
EAE_13175	COG0583	DNA-binding transcription factor activity
EAE_13225	COG1560	Kdo2-lipid A biosynthetic process
EAE_13235	COG1902	pentaerythritol trinitrate reductase activity
EAE_13240	COG3710	Transcriptional regulator
EAE_13245	COG0531	amino acid
EAE_13250	COG1982	Orn Lys Arg decarboxylase major
EAE_13255	COG3104	oligopeptide transport
EAE_13265	COG0402	S-adenosylhomocysteine deaminase activity
EAE_13270	COG0549	Belongs to the carbamate kinase family
EAE_13275	COG1304	FMN binding
EAE_13280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EAE_13290	COG0666	response to abiotic stimulus
EAE_13300	COG0583	DNA-binding transcription factor activity
EAE_13315	COG1566	PFAM secretion protein HlyD family protein
EAE_13335	COG1473	amidohydrolase
EAE_13340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE_13345	COG0667	Aldo Keto reductase
EAE_13385	COG4680	protein conserved in bacteria
EAE_13400	COG0531	amino acid
EAE_13410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAE_13415	COG1012	belongs to the aldehyde dehydrogenase family
EAE_13425	COG1252	NADH dehydrogenase
EAE_13440	COG1113	amino acid transport
EAE_13445	COG0668	transmembrane transport
EAE_13450	COG0477	Major facilitator Superfamily
EAE_13465	COG0778	Nitroreductase
EAE_13470	COG2315	Protein conserved in bacteria
EAE_13500	COG3698	Phosphodiester glycosidase
EAE_13530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAE_13550	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_13560	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAE_13565	COG1129	ABC transporter
EAE_13575	COG1879	ABC-type sugar transport system periplasmic component
EAE_13580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EAE_13585	COG2390	Transcriptional regulator
EAE_13590	COG3959	Transketolase, thiamine diphosphate binding domain
EAE_13595	COG3958	Transketolase
EAE_13600	COG4771	TonB-dependent receptor
EAE_13605	COG2382	esterase
EAE_13610	COG3251	PFAM MbtH domain protein
EAE_13615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EAE_13615	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EAE_13620	COG1120	ATPase activity
EAE_13625	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE_13630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE_13645	COG4592	Periplasmic binding protein
EAE_13650	COG1169	isochorismate synthase
EAE_13655	COG1021	2,3-dihydroxybenzoate-AMP ligase
EAE_13660	COG3433	isochorismatase activity
EAE_13660	COG1535	isochorismatase
EAE_13665	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_13675	COG1966	Carbon starvation protein
EAE_13680	COG2879	small protein
EAE_13700	COG1129	ABC transporter
EAE_13705	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAE_13730	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EAE_13740	COG0436	Aminotransferase
EAE_13745	COG1475	DNA binding
EAE_13750	COG3969	phosphoadenosine phosphosulfate
EAE_13755	COG0583	DNA-binding transcription factor activity
EAE_13765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAE_13775	COG3634	alkyl hydroperoxide reductase activity
EAE_13785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAE_13790	COG3719	Belongs to the RNase T2 family
EAE_13795	COG3069	C4-dicarboxylate transmembrane transporter activity
EAE_13815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAE_13830	COG0583	DNA-binding transcription factor activity
EAE_13845	COG1686	Belongs to the peptidase S11 family
EAE_13850	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EAE_13855	COG0772	Belongs to the SEDS family
EAE_13860	COG0768	penicillin binding
EAE_13870	COG0799	negative regulation of ribosome biogenesis
EAE_13875	COG0406	alpha-ribazole phosphatase activity
EAE_13885	COG1466	dna polymerase III delta subunit
EAE_13900	COG2888	peptidyl-tyrosine sulfation
EAE_13910	COG2831	hemolysin activation secretion protein
EAE_13915	COG1126	abc transporter atp-binding protein
EAE_13920	COG0765	amino acid transport
EAE_13925	COG0765	amino acid transport
EAE_13950	COG1702	phosphate starvation-inducible protein PhoH
EAE_13960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAE_13970	COG0367	asparagine synthase
EAE_13975	COG0647	UMP catabolic process
EAE_13980	COG1846	Transcriptional regulator
EAE_13980	COG1940	carbohydrate kinase activity
EAE_13985	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EAE_14025	COG1053	succinate dehydrogenase
EAE_14030	COG0583	DNA-binding transcription factor activity
EAE_14035	COG0735	belongs to the Fur family
EAE_14050	COG0596	Alpha beta hydrolase
EAE_14060	COG0033	Phosphoglucomutase
EAE_14065	COG0745	RESPONSE REGULATOR receiver
EAE_14070	COG2205	protein histidine kinase activity
EAE_14095	COG0415	Belongs to the DNA photolyase family
EAE_14105	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EAE_14110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EAE_14115	COG1984	allophanate hydrolase subunit 2
EAE_14145	COG0372	Belongs to the citrate synthase family
EAE_14150	COG2009	succinate dehydrogenase
EAE_14155	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EAE_14160	COG1053	succinate dehydrogenase
EAE_14165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EAE_14170	COG0567	Dehydrogenase, E1 component
EAE_14175	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAE_14185	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EAE_14195	COG1271	oxidase subunit
EAE_14200	COG1294	oxidase, subunit
EAE_14205	COG4890	Cyd operon protein YbgT
EAE_14210	COG3790	cyd operon protein YbgE
EAE_14215	COG0824	Thioesterase
EAE_14220	COG0811	peptide transport
EAE_14225	COG0848	biopolymer transport protein
EAE_14230	COG3064	Membrane
EAE_14240	COG2885	chlorophyll binding
EAE_14245	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EAE_14255	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EAE_14265	COG1230	cation diffusion facilitator family transporter
EAE_14275	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAE_14285	COG2017	converts alpha-aldose to the beta-anomer
EAE_14295	COG1085	galactose-1-phosphate uridylyltransferase
EAE_14300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EAE_14305	COG1119	ATPase activity
EAE_14310	COG2005	Transcriptional regulator
EAE_14310	COG3585	molybdate ion transport
EAE_14320	COG0725	ABC transporter, periplasmic molybdate-binding protein
EAE_14325	COG4149	molybdate abc transporter
EAE_14335	COG0561	phosphatase activity
EAE_14360	COG2200	EAL domain
EAE_14365	COG0789	Transcriptional regulator
EAE_14390	COG1595	DNA-templated transcription, initiation
EAE_14400	COG4677	pectinesterase activity
EAE_14435	COG1881	PFAM PEBP family protein
EAE_14440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EAE_14455	COG2226	methyltransferase
EAE_14480	COG0745	RESPONSE REGULATOR receiver
EAE_14500	COG0521	Mo-molybdopterin cofactor biosynthetic process
EAE_14510	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EAE_14515	COG0314	molybdopterin synthase activity
EAE_14520	COG0670	Belongs to the BI1 family
EAE_14525	COG0392	lysyltransferase activity
EAE_14530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAE_14535	COG3568	Endonuclease Exonuclease Phosphatase
EAE_14545	COG0842	Transport permease protein
EAE_14550	COG0842	Transport permease protein
EAE_14555	COG1131	(ABC) transporter
EAE_14565	COG1309	transcriptional regulator
EAE_14570	COG0513	Belongs to the DEAD box helicase family
EAE_14580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAE_14590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EAE_14600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAE_14610	COG0668	transmembrane transport
EAE_14615	COG1126	abc transporter atp-binding protein
EAE_14620	COG0765	amino acid transport
EAE_14625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE_14640	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EAE_14645	COG2194	sulfuric ester hydrolase activity
EAE_14655	COG1321	iron dependent repressor
EAE_14660	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EAE_14665	COG0667	Aldo Keto reductase
EAE_14670	COG2723	6-phospho-beta-galactosidase activity
EAE_14675	COG2188	Transcriptional regulator
EAE_14680	COG1376	ErfK ybiS ycfS ynhG family protein
EAE_14690	COG0488	(ABC) transporter
EAE_14700	COG2271	Major facilitator Superfamily
EAE_14705	COG1609	Transcriptional regulator
EAE_14715	COG0561	phosphatase activity
EAE_14720	COG1882	Formate acetyltransferase
EAE_14725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAE_14730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EAE_14735	COG0303	'Molybdopterin
EAE_14740	COG1446	asparaginase
EAE_14750	COG0747	negative chemotaxis
EAE_14775	COG2133	pyrroloquinoline quinone binding
EAE_14780	COG0625	glutathione transferase activity
EAE_14785	COG1686	Belongs to the peptidase S11 family
EAE_14790	COG1349	DNA-binding transcription factor activity
EAE_14795	COG0671	phosphoesterase, PA-phosphatase related
EAE_14805	COG2814	Major facilitator Superfamily
EAE_14810	COG0561	phosphatase activity
EAE_14815	COG0738	Major facilitator superfamily
EAE_14820	COG3226	Transcriptional regulator
EAE_14825	COG0300	oxidoreductase activity
EAE_14860	COG0778	Nitroreductase
EAE_14875	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EAE_14880	COG3842	ATPase activity
EAE_14885	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAE_14890	COG1177	transmembrane transport
EAE_14900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EAE_14905	COG0745	RESPONSE REGULATOR receiver
EAE_14910	COG5002	protein histidine kinase activity
EAE_14915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE_14920	COG4160	amino acid transport
EAE_14925	COG4215	(ABC) transporter
EAE_14930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE_14935	COG1126	abc transporter atp-binding protein
EAE_14945	COG2067	long-chain fatty acid transport protein
EAE_14955	COG3706	GGDEF domain
EAE_14955	COG5001	Diguanylate cyclase
EAE_14955	COG4251	negative regulation of phosphorylation
EAE_14955	COG2203	Gaf domain
EAE_14960	COG3023	N-Acetylmuramoyl-L-alanine amidase
EAE_14965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAE_14970	COG0702	epimerase
EAE_14975	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EAE_14980	COG0028	Belongs to the TPP enzyme family
EAE_14995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE_15005	COG2431	L-lysine efflux transmembrane transporter activity
EAE_15015	COG3593	DNA synthesis involved in DNA repair
EAE_15020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE_15030	COG1278	Cold shock
EAE_15040	COG0542	response to heat
EAE_15055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EAE_15060	COG4988	ABC transporter
EAE_15065	COG0492	ferredoxin-NADP+ reductase activity
EAE_15085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EAE_15095	COG0243	molybdopterin cofactor binding
EAE_15100	COG0437	4 iron, 4 sulfur cluster binding
EAE_15105	COG3302	dmso reductase anchor subunit
EAE_15110	COG0477	Major facilitator Superfamily
EAE_15115	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAE_15120	COG1882	Formate acetyltransferase
EAE_15125	COG2116	formate transmembrane transporter activity
EAE_15130	COG1944	ATP diphosphatase activity
EAE_15155	COG0539	negative regulation of cytoplasmic translation
EAE_15165	COG0658	competence protein
EAE_15165	COG2333	competence protein COMEC
EAE_15180	COG3214	Protein conserved in bacteria
EAE_15185	COG2835	tetraacyldisaccharide 4'-kinase activity
EAE_15195	COG3173	Aminoglycoside phosphotransferase
EAE_15200	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EAE_15205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EAE_15215	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EAE_15225	COG2989	Protein conserved in bacteria
EAE_15230	COG3108	Peptidase M15
EAE_15235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAE_15240	COG1448	Aminotransferase
EAE_15245	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAE_15255	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EAE_15260	COG0308	aminopeptidase N
EAE_15270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAE_15275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAE_15280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAE_15285	COG0431	NADPH-dependent FMN reductase
EAE_15300	COG3217	Mosc domain protein beta barrel domain protein
EAE_15300	COG0633	Ferredoxin
EAE_15310	COG0488	(ABC) transporter
EAE_15315	COG2995	paraquat-inducible protein a
EAE_15320	COG3008	intermembrane lipid transfer
EAE_15320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EAE_15325	COG3009	Protein conserved in bacteria
EAE_15330	COG3130	regulation of translation
EAE_15340	COG1067	ATP-dependent peptidase activity
EAE_15360	COG3070	regulator of competence-specific genes
EAE_15365	COG1289	transmembrane transporter activity
EAE_15370	COG3304	Inner membrane component domain
EAE_15375	COG0210	DNA helicase
EAE_15385	COG1832	CoA-binding protein
EAE_15405	COG2274	protein secretion by the type I secretion system
EAE_15410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE_15415	COG0438	transferase activity, transferring glycosyl groups
EAE_15445	COG0670	Belongs to the BI1 family
EAE_15455	COG0583	DNA-binding transcription factor activity
EAE_15470	COG0583	DNA-binding transcription factor activity
EAE_15525	COG2198	Histidine kinase
EAE_15525	COG0643	Histidine kinase
EAE_15530	COG0835	chemotaxis
EAE_15535	COG0840	transmembrane signaling receptor activity
EAE_15540	COG0840	transmembrane signaling receptor activity
EAE_15545	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EAE_15555	COG0745	RESPONSE REGULATOR receiver
EAE_15560	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EAE_15565	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EAE_15570	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EAE_15580	COG3418	PFAM FlgN family protein
EAE_15585	COG2747	anti-sigma28 factor FlgM
EAE_15595	COG1815	bacterial-type flagellum-dependent cell motility
EAE_15600	COG1558	bacterial-type flagellum-dependent cell motility
EAE_15605	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EAE_15620	COG4786	Flagellar basal body rod
EAE_15640	COG1256	bacterial-type flagellum assembly
EAE_15675	COG2814	Major facilitator Superfamily
EAE_15685	COG1414	Transcriptional regulator
EAE_15690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EAE_15695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAE_15765	COG2882	bacterial-type flagellum organization
EAE_15770	COG1157	protein secretion by the type III secretion system
EAE_15780	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EAE_15790	COG1677	Flagellar hook-basal body complex protein FliE
EAE_15820	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EAE_15835	COG1191	sigma factor activity
EAE_15875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE_15880	COG1012	belongs to the aldehyde dehydrogenase family
EAE_15885	COG4638	Rieske (2fe-2S)
EAE_15890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EAE_15900	COG0473	3-isopropylmalate dehydrogenase activity
EAE_15905	COG0583	DNA-binding transcription factor activity
EAE_15910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAE_15915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAE_15920	COG1012	belongs to the aldehyde dehydrogenase family
EAE_15925	COG1396	sequence-specific DNA binding
EAE_15925	COG1917	Cupin 2, conserved barrel domain protein
EAE_15930	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EAE_15935	COG0174	glutamine synthetase
EAE_15940	COG0531	amino acid
EAE_16005	COG2233	PERMEase
EAE_16040	COG1309	transcriptional regulator
EAE_16055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAE_16060	COG0628	permease
EAE_16070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EAE_16080	COG2822	iron ion transport
EAE_16090	COG1702	phosphate starvation-inducible protein PhoH
EAE_16095	COG2814	Major facilitator Superfamily
EAE_16115	COG2814	Major facilitator Superfamily
EAE_16130	COG1811	Na channel or pump
EAE_16135	COG0837	glucose binding
EAE_16150	COG0673	inositol 2-dehydrogenase activity
EAE_16170	COG2706	6-phosphogluconolactonase activity
EAE_16180	COG1335	isochorismatase
EAE_16190	COG0583	DNA-binding transcription factor activity
EAE_16205	COG3381	protein complex oligomerization
EAE_16245	COG5645	(Lipo)protein
EAE_16260	COG1560	Kdo2-lipid A biosynthetic process
EAE_16305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAE_16315	COG0673	inositol 2-dehydrogenase activity
EAE_16325	COG2814	Major facilitator Superfamily
EAE_16330	COG0583	DNA-binding transcription factor activity
EAE_16335	COG1530	ribonuclease E activity
EAE_16350	COG1399	metal-binding, possibly nucleic acid-binding protein
EAE_16370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EAE_16375	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_16385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAE_16390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EAE_16395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EAE_16405	COG0470	DNA polymerase III
EAE_16410	COG0084	hydrolase, TatD family'
EAE_16415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAE_16415	COG1263	PTS System
EAE_16420	COG0537	adenosine 5'-monophosphoramidase activity
EAE_16425	COG5633	Lipoprotein
EAE_16435	COG0510	thiamine kinase activity
EAE_16455	COG1252	NADH dehydrogenase
EAE_16460	COG3134	Outer membrane lipoprotein
EAE_16470	COG1309	transcriptional regulator
EAE_16480	COG1376	ErfK ybiS ycfS ynhG family protein
EAE_16480	COG1388	LysM domain
EAE_16485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EAE_16490	COG4591	ABC-type transport system involved in lipoprotein release permease component
EAE_16495	COG1136	(ABC) transporter
EAE_16500	COG4591	ABC-type transport system involved in lipoprotein release permease component
EAE_16510	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EAE_16515	COG0318	PFAM AMP-dependent synthetase and ligase
EAE_16525	COG1177	transmembrane transport
EAE_16545	COG1943	Transposase
EAE_16550	COG2850	peptidyl-arginine hydroxylation
EAE_16565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EAE_16585	COG1187	pseudouridine synthase activity
EAE_16590	COG0538	isocitrate dehydrogenase activity
EAE_16600	COG1403	HNH endonuclease
EAE_16605	COG3272	Protein of unknown function (DUF1722)
EAE_16610	COG0789	Transcriptional regulator
EAE_16620	COG4977	sequence-specific DNA binding
EAE_16625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAE_16650	COG3122	Protein conserved in bacteria
EAE_16665	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EAE_16670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAE_16690	COG0012	GTP binding
EAE_16705	COG0659	secondary active sulfate transmembrane transporter activity
EAE_16735	COG2890	protein-(glutamine-N5) methyltransferase activity
EAE_16755	COG0387	Pfam Sodium calcium exchanger
EAE_16760	COG4572	Cation transport regulator
EAE_16765	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EAE_16775	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EAE_16780	COG3707	response regulator
EAE_16785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAE_16795	COG1116	anion transmembrane transporter activity
EAE_16800	COG2146	nitrite reductase [NAD(P)H] activity
EAE_16800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAE_16805	COG0243	molybdopterin cofactor binding
EAE_16810	COG4932	domain protein
EAE_16815	COG2197	response regulator
EAE_16820	COG3850	Histidine kinase
EAE_16825	COG2223	nitrite transmembrane transporter activity
EAE_16830	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EAE_16835	COG1140	nitrate reductase beta subunit
EAE_16840	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EAE_16845	COG2181	nitrate reductase activity
EAE_16855	COG1522	sequence-specific DNA binding
EAE_16860	COG0788	formyltetrahydrofolate deformylase activity
EAE_16870	COG1752	Esterase of the alpha-beta hydrolase superfamily
EAE_16875	COG0745	RESPONSE REGULATOR receiver
EAE_16880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EAE_16895	COG1012	belongs to the aldehyde dehydrogenase family
EAE_16895	COG1454	alcohol dehydrogenase
EAE_16900	COG2095	MarC family integral membrane protein
EAE_16910	COG0601	transmembrane transport
EAE_16915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAE_16920	COG0444	Belongs to the ABC transporter superfamily
EAE_16930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAE_16945	COG2350	Protein conserved in bacteria
EAE_16950	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EAE_16955	COG3001	Fructosamine kinase
EAE_16965	COG1105	Belongs to the carbohydrate kinase PfkB family
EAE_16970	COG3137	Salt-induced outer membrane protein
EAE_16990	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EAE_17000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAE_17000	COG0072	phenylalanine-tRNA ligase activity
EAE_17020	COG0583	DNA-binding transcription factor activity
EAE_17040	COG0386	Belongs to the glutathione peroxidase family
EAE_17050	COG0791	NLP P60 protein
EAE_17060	COG4256	Hemin uptake protein
EAE_17080	COG0574	Belongs to the PEP-utilizing enzyme family
EAE_17080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAE_17085	COG0628	permease
EAE_17090	COG0277	FAD linked oxidase domain protein
EAE_17090	COG0247	lactate metabolic process
EAE_17095	COG2050	protein possibly involved in aromatic compounds catabolism
EAE_17100	COG3422	double-strand break repair
EAE_17105	COG2261	transglycosylase associated protein
EAE_17120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAE_17125	COG0316	Belongs to the HesB IscA family
EAE_17130	COG0719	Fe-S assembly protein
EAE_17135	COG0396	ATPase activity
EAE_17140	COG0719	Fe-S assembly protein
EAE_17155	COG1376	ErfK ybiS ycfS ynhG family protein
EAE_17180	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EAE_17180	COG1082	Xylose isomerase domain protein TIM barrel
EAE_17185	COG2271	Major facilitator Superfamily
EAE_17190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EAE_17200	COG1120	ATPase activity
EAE_17205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE_17210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EAE_17235	COG0583	DNA-binding transcription factor activity
EAE_17240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAE_17260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAE_17265	COG1116	anion transmembrane transporter activity
EAE_17270	COG4774	siderophore transport
EAE_17275	COG1120	ATPase activity
EAE_17280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE_17285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE_17305	COG0765	amino acid transport
EAE_17310	COG1126	abc transporter atp-binding protein
EAE_17320	COG1473	amidohydrolase
EAE_17325	COG1683	Conserved Protein
EAE_17330	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_17335	COG2378	regulation of single-species biofilm formation
EAE_17355	COG1280	lysine exporter protein (LysE YggA)
EAE_17375	COG2207	Transcriptional regulator
EAE_17385	COG0251	oxidation-reduction process
EAE_17390	COG1309	transcriptional regulator
EAE_17410	COG0406	alpha-ribazole phosphatase activity
EAE_17415	COG1396	sequence-specific DNA binding
EAE_17420	COG0456	acetyltransferase
EAE_17440	COG3383	formate dehydrogenase (NAD+) activity
EAE_17445	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EAE_17455	COG1175	transmembrane transport
EAE_17485	COG1138	Cytochrome C-type biogenesis protein
EAE_17510	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_17515	COG2610	gluconate transmembrane transporter activity
EAE_17520	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAE_17530	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EAE_17540	COG0583	DNA-binding transcription factor activity
EAE_17560	COG4993	Dehydrogenase
EAE_17570	COG4608	Belongs to the ABC transporter superfamily
EAE_17575	COG0444	Belongs to the ABC transporter superfamily
EAE_17600	COG0346	lactoylglutathione lyase activity
EAE_17605	COG1349	DNA-binding transcription factor activity
EAE_17640	COG2233	PERMEase
EAE_17645	COG0493	'glutamate synthase
EAE_17645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAE_17650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAE_17655	COG0402	S-adenosylhomocysteine deaminase activity
EAE_17660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAE_17660	COG0493	'glutamate synthase
EAE_17665	COG2068	MobA-Related Protein
EAE_17670	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAE_17675	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EAE_17675	COG3608	succinylglutamate desuccinylase aspartoacylase
EAE_17680	COG0549	Belongs to the carbamate kinase family
EAE_17690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EAE_17695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAE_17700	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EAE_17705	COG3829	transcription factor binding
EAE_17715	COG2223	nitrite transmembrane transporter activity
EAE_17760	COG0534	Mate efflux family protein
EAE_17765	COG0307	riboflavin synthase, alpha
EAE_17770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EAE_17775	COG2814	Major facilitator Superfamily
EAE_17780	COG0583	DNA-binding transcription factor activity
EAE_17790	COG2814	Major facilitator Superfamily
EAE_17800	COG3708	Transcriptional regulator
EAE_17800	COG2207	Transcriptional regulator
EAE_17805	COG0791	NLP P60 protein
EAE_17810	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EAE_17820	COG0346	lactoylglutathione lyase activity
EAE_17825	COG1902	pentaerythritol trinitrate reductase activity
EAE_17830	COG1309	transcriptional regulator
EAE_17835	COG3313	Fe-S protein
EAE_17840	COG4989	oxidoreductase activity
EAE_17845	COG2032	superoxide dismutase activity
EAE_17850	COG1289	transmembrane transporter activity
EAE_17855	COG1566	PFAM secretion protein HlyD family protein
EAE_17870	COG3706	GGDEF domain
EAE_17885	COG3895	Periplasmic Protein
EAE_17900	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EAE_17905	COG0625	glutathione transferase activity
EAE_17920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EAE_17930	COG4659	FMN binding
EAE_17965	COG2723	6-phospho-beta-galactosidase activity
EAE_17975	COG0673	inositol 2-dehydrogenase activity
EAE_17985	COG5562	phage envelope protein
EAE_18005	COG0425	Belongs to the sulfur carrier protein TusA family
EAE_18010	COG2391	methyltransferase activity
EAE_18020	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EAE_18025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAE_18025	COG1263	PTS System
EAE_18030	COG1609	Transcriptional regulator
EAE_18035	COG5339	Protein conserved in bacteria
EAE_18040	COG1482	cell wall glycoprotein biosynthetic process
EAE_18045	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EAE_18045	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EAE_18055	COG2801	Transposase and inactivated derivatives
EAE_18060	COG0114	fumarate hydratase activity
EAE_18070	COG2205	protein histidine kinase activity
EAE_18080	COG0745	RESPONSE REGULATOR receiver
EAE_18085	COG3136	membrane protein required for alginate biosynthesis
EAE_18095	COG0531	amino acid
EAE_18105	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EAE_18110	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EAE_18125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAE_18130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EAE_18145	COG1473	amidohydrolase
EAE_18155	COG0583	DNA-binding transcription factor activity
EAE_18160	COG2840	Smr protein MutS2
EAE_18165	COG1414	Transcriptional regulator
EAE_18175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EAE_18180	COG0183	Belongs to the thiolase family
EAE_18190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EAE_18195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAE_18205	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EAE_18205	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EAE_18230	COG4565	transcriptional regulatory protein
EAE_18235	COG3290	protein histidine kinase activity
EAE_18240	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EAE_18255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EAE_18265	COG0679	Auxin Efflux Carrier
EAE_18295	COG0628	permease
EAE_18315	COG5001	Diguanylate cyclase
EAE_18315	COG3300	MHYT domain
EAE_18320	COG3591	Belongs to the peptidase S1B family
EAE_18340	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EAE_18345	COG2814	Major facilitator Superfamily
EAE_18350	COG0583	DNA-binding transcription factor activity
EAE_18355	COG1940	carbohydrate kinase activity
EAE_18360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EAE_18375	COG3302	dmso reductase anchor subunit
EAE_18380	COG0437	4 iron, 4 sulfur cluster binding
EAE_18385	COG0243	molybdopterin cofactor binding
EAE_18400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAE_18415	COG2271	Major facilitator Superfamily
EAE_18420	COG4948	Mandelate Racemase Muconate Lactonizing
EAE_18425	COG1063	alcohol dehydrogenase
EAE_18430	COG0477	Major facilitator Superfamily
EAE_18435	COG0246	Mannitol dehydrogenase
EAE_18445	COG1802	Transcriptional regulator
EAE_18450	COG4221	oxidoreductase activity
EAE_18455	COG0339	signal peptide processing
EAE_18465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EAE_18470	COG2223	nitrite transmembrane transporter activity
EAE_18495	COG2203	Gaf domain
EAE_18495	COG2199	diguanylate cyclase activity
EAE_18520	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EAE_18530	COG2814	Major facilitator Superfamily
EAE_18535	COG0697	spore germination
EAE_18550	COG1846	Transcriptional regulator
EAE_18570	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_18590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAE_18600	COG3395	kinase activity
EAE_18605	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EAE_18610	COG1349	DNA-binding transcription factor activity
EAE_18615	COG0583	DNA-binding transcription factor activity
EAE_18620	COG1012	belongs to the aldehyde dehydrogenase family
EAE_18635	COG2199	diguanylate cyclase activity
EAE_18660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAE_18665	COG2271	Major facilitator Superfamily
EAE_18675	COG3622	Belongs to the hyi family
EAE_18680	COG0235	Class ii aldolase
EAE_18685	COG3395	kinase activity
EAE_18690	COG1349	DNA-binding transcription factor activity
EAE_18725	COG0697	spore germination
EAE_18735	COG0477	Major facilitator Superfamily
EAE_18745	COG2070	2-Nitropropane dioxygenase
EAE_18750	COG2011	ABC-type metal ion transport system permease component
EAE_18770	COG4628	conserved protein (DUF2132)
EAE_18775	COG2207	Transcriptional regulator
EAE_18800	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_18805	COG3729	General stress protein
EAE_18810	COG3685	Protein conserved in bacteria
EAE_18815	COG3685	Protein conserved in bacteria
EAE_18820	COG2323	membrane
EAE_18830	COG3111	PFAM Bacterial OB fold (BOF) protein
EAE_18840	COG0626	cystathionine gamma-synthase activity
EAE_18860	COG2610	gluconate transmembrane transporter activity
EAE_18865	COG1312	Catalyzes the dehydration of D-mannonate
EAE_18870	COG0401	homolog of Blt101
EAE_18880	COG4529	Protein conserved in bacteria
EAE_18895	COG2814	Major facilitator Superfamily
EAE_18910	COG0745	RESPONSE REGULATOR receiver
EAE_18910	COG2205	protein histidine kinase activity
EAE_18910	COG4191	Histidine kinase
EAE_18920	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EAE_18925	COG0588	phosphoglycerate mutase activity
EAE_18935	COG2723	6-phospho-beta-galactosidase activity
EAE_18945	COG4580	involved in the transport of maltose and maltodextrins
EAE_18950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAE_18955	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAE_18960	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAE_18965	COG1447	Phosphotransferase system cellobiose-specific component IIA
EAE_18970	COG1940	carbohydrate kinase activity
EAE_18975	COG1609	Transcriptional regulator
EAE_18985	COG0667	Aldo Keto reductase
EAE_18990	COG0667	Aldo Keto reductase
EAE_18995	COG0667	Aldo Keto reductase
EAE_19020	COG0656	L-ascorbic acid biosynthetic process
EAE_19030	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAE_19035	COG0667	Aldo Keto reductase
EAE_19115	COG2814	Major facilitator Superfamily
EAE_19125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EAE_19135	COG0765	amino acid transport
EAE_19140	COG0765	amino acid transport
EAE_19190	COG1953	Uracil, thiamine, allantoin
EAE_19195	COG0402	S-adenosylhomocysteine deaminase activity
EAE_19200	COG2351	hydroxyisourate hydrolase activity
EAE_19210	COG2233	PERMEase
EAE_19215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAE_19245	COG0454	-acetyltransferase
EAE_19250	COG0668	transmembrane transport
EAE_19345	COG0515	serine threonine protein kinase
EAE_19345	COG2815	serine threonine protein kinase
EAE_19455	COG1649	PFAM Uncharacterised BCR, COG1649
EAE_19460	COG2070	2-Nitropropane dioxygenase
EAE_19465	COG0583	DNA-binding transcription factor activity
EAE_19500	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EAE_19505	COG1116	anion transmembrane transporter activity
EAE_19510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAE_19515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAE_19520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAE_19525	COG0076	glutamate decarboxylase activity
EAE_19535	COG2205	protein histidine kinase activity
EAE_19605	COG0583	DNA-binding transcription factor activity
EAE_19615	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EAE_19620	COG1309	transcriptional regulator
EAE_19645	COG2814	Major facilitator Superfamily
EAE_19655	COG0583	DNA-binding transcription factor activity
EAE_19660	COG0583	DNA-binding transcription factor activity
EAE_19665	COG0243	molybdopterin cofactor binding
EAE_19670	COG1271	oxidase subunit
EAE_19675	COG1294	oxidase, subunit
EAE_19685	COG3781	membrane
EAE_19690	COG2837	iron assimilation
EAE_19705	COG1764	response to oxidative stress
EAE_19730	COG1609	Transcriptional regulator
EAE_19750	COG0488	(ABC) transporter
EAE_19760	COG1064	alcohol dehydrogenase
EAE_19765	COG0747	negative chemotaxis
EAE_19775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAE_19785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAE_19795	COG2814	Major facilitator Superfamily
EAE_19855	COG2864	formate dehydrogenase
EAE_19860	COG0437	4 iron, 4 sulfur cluster binding
EAE_19865	COG0243	molybdopterin cofactor binding
EAE_19865	COG3383	formate dehydrogenase (NAD+) activity
EAE_19870	COG3383	formate dehydrogenase (NAD+) activity
EAE_19870	COG0243	molybdopterin cofactor binding
EAE_19875	COG0697	spore germination
EAE_19890	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EAE_19900	COG3485	protocatechuate 3,4-dioxygenase
EAE_19905	COG4829	muconolactone delta-isomerase
EAE_19910	COG4948	Mandelate Racemase Muconate Lactonizing
EAE_19915	COG1414	Transcriptional regulator
EAE_19935	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EAE_19940	COG1140	nitrate reductase beta subunit
EAE_19945	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EAE_19950	COG2181	nitrate reductase activity
EAE_19955	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EAE_19960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAE_19985	COG0625	glutathione transferase activity
EAE_19990	COG3619	membrane
EAE_19995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE_20000	COG1126	abc transporter atp-binding protein
EAE_20015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE_20020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAE_20025	COG1473	amidohydrolase
EAE_20030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAE_20060	COG4772	TonB-dependent receptor
EAE_20065	COG3691	Protein conserved in bacteria
EAE_20070	COG2130	NADP-dependent
EAE_20080	COG1247	-acetyltransferase
EAE_20085	COG3238	Protein conserved in bacteria
EAE_20105	COG0747	negative chemotaxis
EAE_20110	COG1012	belongs to the aldehyde dehydrogenase family
EAE_20115	COG2267	carboxylic ester hydrolase activity
EAE_20130	COG1012	belongs to the aldehyde dehydrogenase family
EAE_20135	COG1177	transmembrane transport
EAE_20140	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAE_20145	COG3842	ATPase activity
EAE_20150	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EAE_20155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAE_20160	COG1271	oxidase subunit
EAE_20165	COG1294	oxidase, subunit
EAE_20180	COG0826	peptidase U32
EAE_20185	COG1396	sequence-specific DNA binding
EAE_20190	COG3135	benzoate transporter
EAE_20200	COG0697	spore germination
EAE_20210	COG0747	negative chemotaxis
EAE_20215	COG2195	Cleaves the N-terminal amino acid of tripeptides
EAE_20220	COG0500	methyltransferase
EAE_20225	COG1275	C4-dicarboxylate transporter malic acid transport protein
EAE_20230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAE_20235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAE_20255	COG0436	Aminotransferase
EAE_20260	COG1823	symporter activity
EAE_20265	COG1335	isochorismatase
EAE_20275	COG2272	Belongs to the type-B carboxylesterase lipase family
EAE_20280	COG5383	Protein conserved in bacteria
EAE_20285	COG3485	protocatechuate 3,4-dioxygenase
EAE_20290	COG3485	protocatechuate 3,4-dioxygenase
EAE_20295	COG0583	DNA-binding transcription factor activity
EAE_20335	COG3038	cytochrome b561
EAE_20370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EAE_20375	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EAE_20380	COG1113	amino acid transport
EAE_20385	COG2988	succinylglutamate desuccinylase activity
EAE_20390	COG3724	N-succinylarginine dihydrolase activity
EAE_20395	COG1012	belongs to the aldehyde dehydrogenase family
EAE_20400	COG3138	arginine N-succinyltransferase
EAE_20405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EAE_20410	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EAE_20435	COG4122	O-methyltransferase activity
EAE_20440	COG1643	Atp-dependent helicase
EAE_20455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAE_20460	COG3327	negative regulation of DNA-templated transcription, initiation
EAE_20465	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EAE_20470	COG0183	Belongs to the thiolase family
EAE_20475	COG2050	protein possibly involved in aromatic compounds catabolism
EAE_20480	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAE_20485	COG1024	Enoyl-CoA hydratase
EAE_20490	COG1024	Enoyl-CoA hydratase
EAE_20500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE_20505	COG2151	metal-sulfur cluster biosynthetic enzyme
EAE_20510	COG3396	Phenylacetate-CoA oxygenase
EAE_20515	COG3460	Phenylacetate-CoA oxygenase
EAE_20520	COG3396	Phenylacetate-CoA oxygenase
EAE_20525	COG2030	dehydratase
EAE_20525	COG1012	belongs to the aldehyde dehydrogenase family
EAE_20545	COG1012	belongs to the aldehyde dehydrogenase family
EAE_20550	COG2207	Transcriptional regulator
EAE_20555	COG3784	Protein of unknown function (DUF1318)
EAE_20565	COG2911	Protein conserved in bacteria
EAE_20570	COG0586	Pfam SNARE associated Golgi protein
EAE_20575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAE_20580	COG3187	Heat shock protein
EAE_20585	COG3042	response to heat
EAE_20590	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAE_20590	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EAE_20590	COG0674	pyruvate-flavodoxin oxidoreductase activity
EAE_20590	COG1013	pyruvate-flavodoxin oxidoreductase activity
EAE_20595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAE_20600	COG0589	response to stress
EAE_20610	COG0513	Belongs to the DEAD box helicase family
EAE_20620	COG0456	acetyltransferase
EAE_20625	COG1940	carbohydrate kinase activity
EAE_20630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAE_20655	COG4172	Belongs to the ABC transporter superfamily
EAE_20660	COG1349	DNA-binding transcription factor activity
EAE_20665	COG0673	inositol 2-dehydrogenase activity
EAE_20675	COG0693	protein deglycase activity
EAE_20745	COG3501	Rhs element vgr protein
EAE_20770	COG4580	involved in the transport of maltose and maltodextrins
EAE_20775	COG2211	Major facilitator Superfamily
EAE_20780	COG3507	Belongs to the glycosyl hydrolase 43 family
EAE_20785	COG0656	L-ascorbic acid biosynthetic process
EAE_20795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAE_20805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EAE_20820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE_20830	COG4166	transmembrane transport
EAE_20835	COG2866	Carboxypeptidase
EAE_20840	COG4948	Mandelate Racemase Muconate Lactonizing
EAE_20845	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EAE_20850	COG3180	Ammonia monooxygenase
EAE_20865	COG3106	COG3106 Predicted ATPase
EAE_20875	COG1983	PspC domain protein
EAE_20885	COG1842	Phage shock protein A
EAE_20890	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EAE_20900	COG1473	amidohydrolase
EAE_20925	COG2135	peptidase activity
EAE_20930	COG2135	peptidase activity
EAE_20935	COG1280	lysine exporter protein (LysE YggA)
EAE_20940	COG1560	Kdo2-lipid A biosynthetic process
EAE_20955	COG3459	Glycosyltransferase 36 associated
EAE_20965	COG1278	Cold shock
EAE_20975	COG0406	alpha-ribazole phosphatase activity
EAE_20980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAE_21025	COG1196	nuclear chromosome segregation
EAE_21025	COG1196	nuclear chromosome segregation
EAE_21125	COG3179	chitinase
EAE_21145	COG0484	heat shock protein binding
EAE_21230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAE_21245	COG4171	peptide transport system, permease
EAE_21255	COG4172	Belongs to the ABC transporter superfamily
EAE_21260	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EAE_21270	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EAE_21275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAE_21275	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAE_21290	COG1349	DNA-binding transcription factor activity
EAE_21300	COG0023	Translation Initiation Factor
EAE_21310	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EAE_21315	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EAE_21320	COG0671	phosphoesterase, PA-phosphatase related
EAE_21330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EAE_21365	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_21370	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EAE_21375	COG2207	Transcriptional regulator
EAE_21380	COG1472	Belongs to the glycosyl hydrolase 3 family
EAE_21385	COG2211	Major facilitator Superfamily
EAE_21395	COG1716	ATPase activity
EAE_21395	COG5001	Diguanylate cyclase
EAE_21400	COG5001	Diguanylate cyclase
EAE_21400	COG1716	ATPase activity
EAE_21405	COG0009	L-threonylcarbamoyladenylate synthase
EAE_21415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EAE_21420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAE_21420	COG0512	Glutamine amidotransferase of anthranilate synthase
EAE_21425	COG0135	phosphoribosylanthranilate isomerase activity
EAE_21425	COG0134	indole-3-glycerol-phosphate synthase activity
EAE_21450	COG1566	PFAM secretion protein HlyD family protein
EAE_21465	COG0583	DNA-binding transcription factor activity
EAE_21470	COG3047	cAMP biosynthetic process
EAE_21475	COG0727	PFAM Uncharacterised protein family (UPF0153)
EAE_21505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAE_21510	COG1988	membrane-bound metal-dependent
EAE_21515	COG1823	symporter activity
EAE_21525	COG0753	catalase activity
EAE_21535	COG1486	melibiose metabolic process
EAE_21540	COG1917	Cupin 2, conserved barrel domain protein
EAE_21540	COG2169	Transcriptional regulator
EAE_21545	COG1447	Phosphotransferase system cellobiose-specific component IIA
EAE_21550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAE_21555	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EAE_21560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAE_21570	COG0322	excinuclease ABC activity
EAE_21575	COG3678	ATP-independent chaperone mediated protein folding
EAE_21595	COG3138	arginine N-succinyltransferase
EAE_21605	COG0708	Exodeoxyribonuclease III
EAE_21610	COG0398	Pfam SNARE associated Golgi protein
EAE_21615	COG0398	Pfam SNARE associated Golgi protein
EAE_21620	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAE_21625	COG4134	Bacterial extracellular solute-binding protein
EAE_21630	COG4135	transport system, permease component
EAE_21635	COG4136	ATPase activity
EAE_21640	COG2897	thiosulfate sulfurtransferase activity
EAE_21645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EAE_21650	COG0494	nUDIX hydrolase
EAE_21660	COG3321	synthase
EAE_21660	COG1028	Short-chain dehydrogenase reductase Sdr
EAE_21660	COG0604	alcohol dehydrogenase
EAE_21670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EAE_21675	COG0709	Synthesizes selenophosphate from selenide and ATP
EAE_21685	COG0778	Nitroreductase
EAE_21690	COG0616	signal peptide processing
EAE_21695	COG0252	asparaginase activity
EAE_21700	COG1335	isochorismatase
EAE_21710	COG3139	Protein of unknown function (DUF1315)
EAE_21730	COG3713	MltA-interacting MipA family protein
EAE_21735	COG2766	serine protein kinase
EAE_21745	COG2199	diguanylate cyclase activity
EAE_21750	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAE_21760	COG2207	Transcriptional regulator
EAE_21765	COG2807	transmembrane transport
EAE_21770	COG0504	CTP synthase activity
EAE_21775	COG3189	MarR family transcriptional regulator
EAE_21780	COG3042	response to heat
EAE_21785	COG2199	diguanylate cyclase activity
EAE_21785	COG2203	Gaf domain
EAE_21800	COG3182	Iron-regulated membrane protein
EAE_21810	COG1560	Kdo2-lipid A biosynthetic process
EAE_21815	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EAE_21840	COG3300	MHYT domain
EAE_21840	COG5001	Diguanylate cyclase
EAE_21865	COG3209	COG3209 Rhs family protein
EAE_21875	COG3209	COG3209 Rhs family protein
EAE_21900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAE_22010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAE_22020	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EAE_22030	COG1760	l-serine dehydratase
EAE_22035	COG1882	Formate acetyltransferase
EAE_22040	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAE_22055	COG0583	DNA-binding transcription factor activity
EAE_22060	COG2814	Major facilitator Superfamily
EAE_22075	COG4774	siderophore transport
EAE_22085	COG1619	proteins homologs of microcin C7 resistance protein MccF
EAE_22105	COG2719	SpoVR family
EAE_22130	COG2135	peptidase activity
EAE_22145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAE_22350	COG3772	lysozyme
EAE_22510	COG0582	viral genome integration into host DNA
EAE_22520	COG0179	Fumarylacetoacetate (FAA) hydrolase
EAE_22535	COG2894	cell division
EAE_22545	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EAE_22555	COG3065	identical protein binding
EAE_22565	COG1199	ATP-dependent helicase activity
EAE_22570	COG0251	oxidation-reduction process
EAE_22590	COG1760	l-serine dehydratase
EAE_22595	COG2200	EAL domain
EAE_22600	COG1253	flavin adenine dinucleotide binding
EAE_22605	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAE_22605	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EAE_22610	COG3715	PTS system
EAE_22615	COG3716	PTS system mannose fructose sorbose family IID component
EAE_22630	COG2226	methyltransferase
EAE_22635	COG0768	penicillin binding
EAE_22660	COG1414	Transcriptional regulator
EAE_22665	COG2814	Major facilitator Superfamily
EAE_22685	COG1956	GAF domain-containing protein
EAE_22690	COG2995	paraquat-inducible protein a
EAE_22695	COG3008	intermembrane lipid transfer
EAE_22720	COG2990	Protein conserved in bacteria
EAE_22760	COG1276	copper resistance
EAE_22765	COG2372	response to copper ion
EAE_22775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EAE_22780	COG1770	oligopeptidase
EAE_22785	COG2979	Protein of unknown function (DUF533)
EAE_22790	COG3141	response to X-ray
EAE_22800	COG0800	Aldolase
EAE_22805	COG0129	dihydroxy-acid dehydratase activity
EAE_22810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EAE_22815	COG1737	Transcriptional regulator
EAE_22825	COG1560	Kdo2-lipid A biosynthetic process
EAE_22830	COG0739	heme binding
EAE_22835	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EAE_22845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EAE_22870	COG0494	nUDIX hydrolase
EAE_22880	COG1335	isochorismatase
EAE_22885	COG1801	Protein of unknown function DUF72
EAE_22890	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EAE_22910	COG3102	Protein conserved in bacteria
EAE_22920	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EAE_22950	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAE_22960	COG1879	ABC-type sugar transport system periplasmic component
EAE_22965	COG1528	Iron-storage protein
EAE_22975	COG0477	Major facilitator Superfamily
EAE_22985	COG1528	Iron-storage protein
EAE_22995	COG0814	amino acid
EAE_23000	COG3318	Belongs to the UPF0149 family
EAE_23000	COG3012	SEC-C Motif Domain Protein
EAE_23005	COG3152	Membrane
EAE_23010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAE_23025	COG2197	response regulator
EAE_23035	COG2197	response regulator
EAE_23040	COG1126	abc transporter atp-binding protein
EAE_23045	COG0765	amino acid transport
EAE_23055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE_23060	COG0366	Alpha amylase catalytic
EAE_23090	COG5475	Uncharacterized small protein (DUF2158)
EAE_23095	COG2354	Protein conserved in bacteria
EAE_23100	COG0697	spore germination
EAE_23105	COG3727	T/G mismatch-specific endonuclease activity
EAE_23110	COG0270	DNA (cytosine-5-)-methyltransferase activity
EAE_23115	COG1418	mRNA catabolic process
EAE_23125	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAE_23155	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EAE_23170	COG1376	ErfK ybiS ycfS ynhG family protein
EAE_23185	COG2977	Belongs to the P-Pant transferase superfamily
EAE_23205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EAE_23220	COG1181	Belongs to the D-alanine--D-alanine ligase family
EAE_23240	COG0534	Mate efflux family protein
EAE_23260	COG3615	Tellurite resistance protein tehB
EAE_23265	COG3300	MHYT domain
EAE_23265	COG5001	Diguanylate cyclase
EAE_23275	COG0477	Major facilitator Superfamily
EAE_23280	COG0095	Lipoate-protein ligase
EAE_23290	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EAE_23315	COG1289	transmembrane transporter activity
EAE_23325	COG1686	Belongs to the peptidase S11 family
EAE_23330	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EAE_23330	COG2755	lipolytic protein G-D-S-L family
EAE_23340	COG2925	Exonuclease
EAE_23345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EAE_23350	COG0640	Transcriptional regulator
EAE_23355	COG0531	amino acid
EAE_23360	COG0583	DNA-binding transcription factor activity
EAE_23365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAE_23375	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EAE_23390	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EAE_23415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EAE_23425	COG1088	dTDP-glucose 4,6-dehydratase activity
EAE_23460	COG1088	dTDP-glucose 4,6-dehydratase activity
EAE_23465	COG1215	transferase activity, transferring glycosyl groups
EAE_23475	COG2244	polysaccharide biosynthetic process
EAE_23480	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EAE_23500	COG0463	Glycosyl transferase, family 2
EAE_23555	COG1253	flavin adenine dinucleotide binding
EAE_23560	COG2982	Protein involved in outer membrane biogenesis
EAE_23585	COG0443	Heat shock 70 kDa protein
EAE_23610	COG2205	protein histidine kinase activity
EAE_23615	COG0745	RESPONSE REGULATOR receiver
EAE_23620	COG0826	peptidase U32
EAE_23635	COG1070	Carbohydrate kinase
EAE_23645	COG2390	Transcriptional regulator
EAE_23670	COG1830	Aldolase
EAE_23675	COG0351	phosphomethylpyrimidine kinase
EAE_23700	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EAE_23710	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EAE_23720	COG0583	DNA-binding transcription factor activity
EAE_23730	COG2252	PERMEase
EAE_23735	COG0583	DNA-binding transcription factor activity
EAE_23740	COG5455	response to cobalt ion
EAE_23750	COG0489	protein tyrosine kinase activity
EAE_23765	COG4808	Protein conserved in bacteria
EAE_23770	COG4807	Protein conserved in bacteria
EAE_23780	COG3275	phosphorelay sensor kinase activity
EAE_23785	COG0789	Transcriptional regulator
EAE_23795	COG1174	glycine betaine transport
EAE_23800	COG1125	glycine betaine transport
EAE_23805	COG1174	glycine betaine transport
EAE_23810	COG1732	Glycine betaine
EAE_23815	COG1472	Belongs to the glycosyl hydrolase 3 family
EAE_23820	COG0277	FAD linked oxidase domain protein
EAE_23830	COG1686	Belongs to the peptidase S11 family
EAE_23840	COG0586	Pfam SNARE associated Golgi protein
EAE_23845	COG1538	Outer membrane efflux protein
EAE_23850	COG2226	methyltransferase
EAE_23855	COG2723	6-phospho-beta-galactosidase activity
EAE_23870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAE_23875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAE_23880	COG0625	glutathione transferase activity
EAE_23895	COG2271	Major facilitator Superfamily
EAE_23900	COG0583	DNA-binding transcription factor activity
EAE_23910	COG1346	cytolysis
EAE_23920	COG2949	membrane
EAE_23950	COG2311	Membrane
EAE_23980	COG4771	TonB-dependent receptor
EAE_23985	COG0833	amino acid
EAE_24000	COG0583	DNA-binding transcription factor activity
EAE_24005	COG2855	membrane
EAE_24015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAE_24015	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EAE_24015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EAE_24020	COG1105	Belongs to the carbohydrate kinase PfkB family
EAE_24050	COG1312	Catalyzes the dehydration of D-mannonate
EAE_24055	COG0246	Mannitol dehydrogenase
EAE_24060	COG0523	cobalamin synthesis protein
EAE_24065	COG0671	phosphoesterase, PA-phosphatase related
EAE_24070	COG0791	NLP P60 protein
EAE_24075	COG2200	EAL domain
EAE_24080	COG4166	transmembrane transport
EAE_24085	COG4174	ABC transporter (Permease)
EAE_24090	COG4239	(ABC) transporter, permease
EAE_24095	COG4172	Belongs to the ABC transporter superfamily
EAE_24105	COG2814	Major facilitator Superfamily
EAE_24110	COG1187	pseudouridine synthase activity
EAE_24115	COG1061	Type III restriction enzyme res subunit
EAE_24135	COG0494	nUDIX hydrolase
EAE_24140	COG1349	DNA-binding transcription factor activity
EAE_24160	COG0628	permease
EAE_24175	COG0659	secondary active sulfate transmembrane transporter activity
EAE_24180	COG2239	Acts as a magnesium transporter
EAE_24185	COG4615	Cyclic peptide transporter
EAE_24195	COG2169	Transcriptional regulator
EAE_24195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EAE_24215	COG0642	Histidine kinase
EAE_24215	COG2198	Histidine kinase
EAE_24250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EAE_24255	COG0584	glycerophosphoryl diester phosphodiesterase
EAE_24260	COG2271	Major facilitator Superfamily
EAE_24265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EAE_24275	COG0247	lactate metabolic process
EAE_24295	COG0642	Histidine kinase
EAE_24320	COG0318	PFAM AMP-dependent synthetase and ligase
EAE_24345	COG1169	isochorismate synthase
EAE_24350	COG2153	protein acetylation
EAE_24365	COG2801	Transposase and inactivated derivatives
EAE_24375	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAE_24380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EAE_24390	COG0839	Belongs to the complex I subunit 6 family
EAE_24435	COG0583	DNA-binding transcription factor activity
EAE_24440	COG0436	Aminotransferase
EAE_24450	COG0490	domain, Protein
EAE_24450	COG0471	metal ion transport
EAE_24455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAE_24485	COG0622	Phosphoesterase
EAE_24490	COG0625	glutathione transferase activity
EAE_24495	COG0625	glutathione transferase activity
EAE_24500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EAE_24505	COG1090	epimerase
EAE_24525	COG4598	ABC transporter
EAE_24530	COG4160	amino acid transport
EAE_24545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAE_24555	COG0163	prenyltransferase activity
EAE_24560	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EAE_24565	COG1286	toxin biosynthetic process
EAE_24570	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EAE_24575	COG0285	dihydrofolate synthase activity
EAE_24585	COG0586	Pfam SNARE associated Golgi protein
EAE_24595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EAE_24610	COG2814	Major facilitator Superfamily
EAE_24615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAE_24630	COG3101	peptidyl-lysine hydroxylation
EAE_24635	COG0730	response to heat
EAE_24660	COG2062	phosphohistidine phosphatase, SixA
EAE_24675	COG3691	Protein conserved in bacteria
EAE_24685	COG2853	Lipoprotein
EAE_24690	COG2116	formate transmembrane transporter activity
EAE_24695	COG0582	viral genome integration into host DNA
EAE_24725	COG0745	RESPONSE REGULATOR receiver
EAE_24740	COG2801	Transposase and inactivated derivatives
EAE_24745	COG2801	Transposase and inactivated derivatives
EAE_24755	COG0697	spore germination