locus-tag	class	description
GIY01_RS00055	COG0588	phosphoglycerate mutase activity
GIY01_RS00060	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GIY01_RS00070	COG0745	RESPONSE REGULATOR receiver
GIY01_RS00070	COG4191	Histidine kinase
GIY01_RS00070	COG2205	protein histidine kinase activity
GIY01_RS00085	COG2814	Major facilitator Superfamily
GIY01_RS00100	COG4529	Protein conserved in bacteria
GIY01_RS00110	COG0401	homolog of Blt101
GIY01_RS00115	COG1312	Catalyzes the dehydration of D-mannonate
GIY01_RS00120	COG2610	gluconate transmembrane transporter activity
GIY01_RS00140	COG0626	cystathionine gamma-synthase activity
GIY01_RS00150	COG3111	PFAM Bacterial OB fold (BOF) protein
GIY01_RS00160	COG2323	membrane
GIY01_RS00165	COG3685	Protein conserved in bacteria
GIY01_RS00170	COG3685	Protein conserved in bacteria
GIY01_RS00175	COG3729	General stress protein
GIY01_RS00180	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS00205	COG2207	Transcriptional regulator
GIY01_RS00210	COG4628	conserved protein (DUF2132)
GIY01_RS00230	COG2011	ABC-type metal ion transport system permease component
GIY01_RS00235	COG2070	2-Nitropropane dioxygenase
GIY01_RS00245	COG0477	Major facilitator Superfamily
GIY01_RS00250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GIY01_RS00255	COG0697	spore germination
GIY01_RS00285	COG1349	DNA-binding transcription factor activity
GIY01_RS00290	COG3395	kinase activity
GIY01_RS00295	COG0235	Class ii aldolase
GIY01_RS00300	COG3622	Belongs to the hyi family
GIY01_RS00305	COG2271	Major facilitator Superfamily
GIY01_RS00310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GIY01_RS00335	COG2199	diguanylate cyclase activity
GIY01_RS00350	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS00355	COG0583	DNA-binding transcription factor activity
GIY01_RS00360	COG1349	DNA-binding transcription factor activity
GIY01_RS00365	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GIY01_RS00370	COG3395	kinase activity
GIY01_RS00380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GIY01_RS00400	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS00420	COG1846	Transcriptional regulator
GIY01_RS00435	COG0697	spore germination
GIY01_RS00440	COG2814	Major facilitator Superfamily
GIY01_RS00450	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GIY01_RS00475	COG2199	diguanylate cyclase activity
GIY01_RS00475	COG2203	Gaf domain
GIY01_RS00495	COG2223	nitrite transmembrane transporter activity
GIY01_RS00500	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GIY01_RS00515	COG4221	oxidoreductase activity
GIY01_RS00520	COG1802	Transcriptional regulator
GIY01_RS00530	COG0246	Mannitol dehydrogenase
GIY01_RS00535	COG0477	Major facilitator Superfamily
GIY01_RS00540	COG1063	alcohol dehydrogenase
GIY01_RS00545	COG4948	Mandelate Racemase Muconate Lactonizing
GIY01_RS00550	COG2271	Major facilitator Superfamily
GIY01_RS00565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GIY01_RS00585	COG0437	4 iron, 4 sulfur cluster binding
GIY01_RS00590	COG3302	dmso reductase anchor subunit
GIY01_RS00605	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GIY01_RS00610	COG1940	carbohydrate kinase activity
GIY01_RS00615	COG0583	DNA-binding transcription factor activity
GIY01_RS00620	COG2814	Major facilitator Superfamily
GIY01_RS00625	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GIY01_RS00645	COG3591	Belongs to the peptidase S1B family
GIY01_RS00650	COG5001	Diguanylate cyclase
GIY01_RS00650	COG3300	MHYT domain
GIY01_RS00670	COG0628	permease
GIY01_RS00700	COG0679	Auxin Efflux Carrier
GIY01_RS00710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GIY01_RS00725	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GIY01_RS00730	COG3290	protein histidine kinase activity
GIY01_RS00735	COG4565	transcriptional regulatory protein
GIY01_RS00760	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GIY01_RS00760	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GIY01_RS00770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GIY01_RS00775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GIY01_RS00785	COG0183	Belongs to the thiolase family
GIY01_RS00790	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GIY01_RS00800	COG1414	Transcriptional regulator
GIY01_RS00805	COG2840	Smr protein MutS2
GIY01_RS00810	COG0583	DNA-binding transcription factor activity
GIY01_RS00820	COG1473	amidohydrolase
GIY01_RS00825	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GIY01_RS00830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GIY01_RS00835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GIY01_RS00850	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GIY01_RS00855	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GIY01_RS00865	COG0531	amino acid
GIY01_RS00875	COG3136	membrane protein required for alginate biosynthesis
GIY01_RS00880	COG0745	RESPONSE REGULATOR receiver
GIY01_RS00960	COG0582	viral genome integration into host DNA
GIY01_RS00965	COG2205	protein histidine kinase activity
GIY01_RS00985	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GIY01_RS00985	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GIY01_RS00990	COG1482	cell wall glycoprotein biosynthetic process
GIY01_RS00995	COG5339	Protein conserved in bacteria
GIY01_RS01000	COG1609	Transcriptional regulator
GIY01_RS01005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIY01_RS01005	COG1263	PTS System
GIY01_RS01010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GIY01_RS01020	COG2391	methyltransferase activity
GIY01_RS01025	COG0425	Belongs to the sulfur carrier protein TusA family
GIY01_RS01040	COG1464	Belongs to the NlpA lipoprotein family
GIY01_RS01045	COG5562	phage envelope protein
GIY01_RS01055	COG0673	inositol 2-dehydrogenase activity
GIY01_RS01065	COG2723	6-phospho-beta-galactosidase activity
GIY01_RS01100	COG4659	FMN binding
GIY01_RS01110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GIY01_RS01125	COG0625	glutathione transferase activity
GIY01_RS01130	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GIY01_RS01145	COG3895	Periplasmic Protein
GIY01_RS01160	COG3706	GGDEF domain
GIY01_RS01175	COG1566	PFAM secretion protein HlyD family protein
GIY01_RS01180	COG1289	transmembrane transporter activity
GIY01_RS01185	COG2032	superoxide dismutase activity
GIY01_RS01190	COG4989	oxidoreductase activity
GIY01_RS01195	COG3313	Fe-S protein
GIY01_RS01200	COG1309	transcriptional regulator
GIY01_RS01205	COG1902	pentaerythritol trinitrate reductase activity
GIY01_RS01210	COG0346	lactoylglutathione lyase activity
GIY01_RS01220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GIY01_RS01225	COG0791	NLP P60 protein
GIY01_RS01230	COG3708	Transcriptional regulator
GIY01_RS01230	COG2207	Transcriptional regulator
GIY01_RS01240	COG2814	Major facilitator Superfamily
GIY01_RS01255	COG0583	DNA-binding transcription factor activity
GIY01_RS01260	COG2814	Major facilitator Superfamily
GIY01_RS01265	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GIY01_RS01270	COG0307	riboflavin synthase, alpha
GIY01_RS01275	COG0534	Mate efflux family protein
GIY01_RS01335	COG2223	nitrite transmembrane transporter activity
GIY01_RS01345	COG3829	transcription factor binding
GIY01_RS01350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GIY01_RS01355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GIY01_RS01360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GIY01_RS01370	COG0549	Belongs to the carbamate kinase family
GIY01_RS01375	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GIY01_RS01375	COG3608	succinylglutamate desuccinylase aspartoacylase
GIY01_RS01380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GIY01_RS01385	COG2068	MobA-Related Protein
GIY01_RS01405	COG0583	DNA-binding transcription factor activity
GIY01_RS01415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GIY01_RS01425	COG1250	3-hydroxyacyl-CoA dehydrogenase
GIY01_RS01430	COG2610	gluconate transmembrane transporter activity
GIY01_RS01435	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS01465	COG1138	Cytochrome C-type biogenesis protein
GIY01_RS01495	COG1175	transmembrane transport
GIY01_RS01515	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GIY01_RS01520	COG3383	formate dehydrogenase (NAD+) activity
GIY01_RS01540	COG0456	acetyltransferase
GIY01_RS01545	COG1396	sequence-specific DNA binding
GIY01_RS01550	COG0406	alpha-ribazole phosphatase activity
GIY01_RS01570	COG1309	transcriptional regulator
GIY01_RS01575	COG0251	oxidation-reduction process
GIY01_RS01600	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS01605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GIY01_RS01610	COG0697	spore germination
GIY01_RS01615	COG2271	Major facilitator Superfamily
GIY01_RS01630	COG0163	prenyltransferase activity
GIY01_RS01635	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GIY01_RS01645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GIY01_RS01680	COG2378	regulation of single-species biofilm formation
GIY01_RS01685	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS01690	COG1683	Conserved Protein
GIY01_RS01695	COG1473	amidohydrolase
GIY01_RS01705	COG1126	abc transporter atp-binding protein
GIY01_RS01710	COG0765	amino acid transport
GIY01_RS01730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIY01_RS01735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIY01_RS01740	COG1120	ATPase activity
GIY01_RS01745	COG4774	siderophore transport
GIY01_RS01750	COG1116	anion transmembrane transporter activity
GIY01_RS01755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GIY01_RS01775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GIY01_RS01780	COG0583	DNA-binding transcription factor activity
GIY01_RS01805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GIY01_RS01810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIY01_RS01815	COG1120	ATPase activity
GIY01_RS01825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GIY01_RS01830	COG2271	Major facilitator Superfamily
GIY01_RS01835	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GIY01_RS01835	COG1082	Xylose isomerase domain protein TIM barrel
GIY01_RS01860	COG1376	ErfK ybiS ycfS ynhG family protein
GIY01_RS01875	COG0719	Fe-S assembly protein
GIY01_RS01880	COG0396	ATPase activity
GIY01_RS01885	COG0719	Fe-S assembly protein
GIY01_RS01890	COG0316	Belongs to the HesB IscA family
GIY01_RS01900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GIY01_RS01915	COG2261	transglycosylase associated protein
GIY01_RS01920	COG3422	double-strand break repair
GIY01_RS01925	COG2050	protein possibly involved in aromatic compounds catabolism
GIY01_RS01930	COG0277	FAD linked oxidase domain protein
GIY01_RS01930	COG0247	lactate metabolic process
GIY01_RS01935	COG0628	permease
GIY01_RS01945	COG0574	Belongs to the PEP-utilizing enzyme family
GIY01_RS01945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GIY01_RS01960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GIY01_RS01965	COG4256	Hemin uptake protein
GIY01_RS01975	COG0791	NLP P60 protein
GIY01_RS01985	COG0386	Belongs to the glutathione peroxidase family
GIY01_RS02005	COG0583	DNA-binding transcription factor activity
GIY01_RS02025	COG0072	phenylalanine-tRNA ligase activity
GIY01_RS02025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GIY01_RS02040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GIY01_RS02060	COG3137	Salt-induced outer membrane protein
GIY01_RS02065	COG1105	Belongs to the carbohydrate kinase PfkB family
GIY01_RS02075	COG3001	Fructosamine kinase
GIY01_RS02080	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GIY01_RS02085	COG2350	Protein conserved in bacteria
GIY01_RS02105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GIY01_RS02115	COG0444	Belongs to the ABC transporter superfamily
GIY01_RS02120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GIY01_RS02125	COG0601	transmembrane transport
GIY01_RS02135	COG2095	MarC family integral membrane protein
GIY01_RS02140	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS02140	COG1454	alcohol dehydrogenase
GIY01_RS02155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GIY01_RS02160	COG0745	RESPONSE REGULATOR receiver
GIY01_RS02165	COG1752	Esterase of the alpha-beta hydrolase superfamily
GIY01_RS02175	COG0788	formyltetrahydrofolate deformylase activity
GIY01_RS02225	COG1522	sequence-specific DNA binding
GIY01_RS02235	COG2181	nitrate reductase activity
GIY01_RS02240	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GIY01_RS02245	COG1140	nitrate reductase beta subunit
GIY01_RS02250	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GIY01_RS02255	COG2223	nitrite transmembrane transporter activity
GIY01_RS02260	COG3850	Histidine kinase
GIY01_RS02265	COG2197	response regulator
GIY01_RS02270	COG4932	domain protein
GIY01_RS02275	COG0243	molybdopterin cofactor binding
GIY01_RS02280	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GIY01_RS02280	COG2146	nitrite reductase [NAD(P)H] activity
GIY01_RS02285	COG1116	anion transmembrane transporter activity
GIY01_RS02295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GIY01_RS02300	COG3707	response regulator
GIY01_RS02305	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GIY01_RS02315	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GIY01_RS02325	COG4572	Cation transport regulator
GIY01_RS02330	COG0387	Pfam Sodium calcium exchanger
GIY01_RS02350	COG2890	protein-(glutamine-N5) methyltransferase activity
GIY01_RS02380	COG0659	secondary active sulfate transmembrane transporter activity
GIY01_RS02395	COG0012	GTP binding
GIY01_RS02400	COG3477	response to acidic pH
GIY01_RS02405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GIY01_RS02410	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GIY01_RS02420	COG3122	Protein conserved in bacteria
GIY01_RS02445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIY01_RS02450	COG4977	sequence-specific DNA binding
GIY01_RS02460	COG0789	Transcriptional regulator
GIY01_RS02465	COG3272	Protein of unknown function (DUF1722)
GIY01_RS02470	COG1403	HNH endonuclease
GIY01_RS02480	COG0538	isocitrate dehydrogenase activity
GIY01_RS02485	COG1187	pseudouridine synthase activity
GIY01_RS02505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GIY01_RS02520	COG2850	peptidyl-arginine hydroxylation
GIY01_RS02525	COG1943	Transposase
GIY01_RS02545	COG1177	transmembrane transport
GIY01_RS02555	COG0318	PFAM AMP-dependent synthetase and ligase
GIY01_RS02565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GIY01_RS02570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GIY01_RS02575	COG0698	ribose 5-phosphate isomerase
GIY01_RS02580	COG3731	PTS system glucitol sorbitol-specific IIA component
GIY01_RS02600	COG3395	kinase activity
GIY01_RS02615	COG2390	Transcriptional regulator
GIY01_RS02620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GIY01_RS02630	COG4591	ABC-type transport system involved in lipoprotein release permease component
GIY01_RS02635	COG1136	(ABC) transporter
GIY01_RS02640	COG4591	ABC-type transport system involved in lipoprotein release permease component
GIY01_RS02645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GIY01_RS02650	COG1376	ErfK ybiS ycfS ynhG family protein
GIY01_RS02650	COG1388	LysM domain
GIY01_RS02660	COG1309	transcriptional regulator
GIY01_RS02670	COG3134	Outer membrane lipoprotein
GIY01_RS02675	COG1252	NADH dehydrogenase
GIY01_RS02695	COG0510	thiamine kinase activity
GIY01_RS02705	COG5633	Lipoprotein
GIY01_RS02710	COG0537	adenosine 5'-monophosphoramidase activity
GIY01_RS02715	COG1263	PTS System
GIY01_RS02715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIY01_RS02720	COG0084	hydrolase, TatD family'
GIY01_RS02725	COG0470	DNA polymerase III
GIY01_RS02735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GIY01_RS02740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GIY01_RS02745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GIY01_RS02755	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS02760	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GIY01_RS02780	COG1399	metal-binding, possibly nucleic acid-binding protein
GIY01_RS02795	COG1530	ribonuclease E activity
GIY01_RS02800	COG0583	DNA-binding transcription factor activity
GIY01_RS02805	COG2814	Major facilitator Superfamily
GIY01_RS02815	COG0673	inositol 2-dehydrogenase activity
GIY01_RS02825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GIY01_RS02870	COG1560	Kdo2-lipid A biosynthetic process
GIY01_RS02885	COG5645	(Lipo)protein
GIY01_RS02925	COG3381	protein complex oligomerization
GIY01_RS02950	COG0583	DNA-binding transcription factor activity
GIY01_RS02960	COG1335	isochorismatase
GIY01_RS02970	COG1702	phosphate starvation-inducible protein PhoH
GIY01_RS02980	COG2822	iron ion transport
GIY01_RS02990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GIY01_RS03000	COG0628	permease
GIY01_RS03005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GIY01_RS03020	COG1309	transcriptional regulator
GIY01_RS03070	COG2233	PERMEase
GIY01_RS03080	COG3729	General stress protein
GIY01_RS03140	COG0531	amino acid
GIY01_RS03145	COG0174	glutamine synthetase
GIY01_RS03150	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GIY01_RS03155	COG1917	Cupin 2, conserved barrel domain protein
GIY01_RS03155	COG1396	sequence-specific DNA binding
GIY01_RS03160	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS03165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GIY01_RS03170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GIY01_RS03175	COG0583	DNA-binding transcription factor activity
GIY01_RS03180	COG0473	3-isopropylmalate dehydrogenase activity
GIY01_RS03185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GIY01_RS03190	COG4638	Rieske (2fe-2S)
GIY01_RS03195	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS03200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GIY01_RS03240	COG1191	sigma factor activity
GIY01_RS03255	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GIY01_RS03285	COG1677	Flagellar hook-basal body complex protein FliE
GIY01_RS03295	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GIY01_RS03305	COG1157	protein secretion by the type III secretion system
GIY01_RS03310	COG2882	bacterial-type flagellum organization
GIY01_RS03380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GIY01_RS03385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GIY01_RS03390	COG1414	Transcriptional regulator
GIY01_RS03400	COG2814	Major facilitator Superfamily
GIY01_RS03435	COG1256	bacterial-type flagellum assembly
GIY01_RS03455	COG4786	Flagellar basal body rod
GIY01_RS03470	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GIY01_RS03475	COG1558	bacterial-type flagellum-dependent cell motility
GIY01_RS03480	COG1815	bacterial-type flagellum-dependent cell motility
GIY01_RS03490	COG2747	anti-sigma28 factor FlgM
GIY01_RS03495	COG3418	PFAM FlgN family protein
GIY01_RS03505	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GIY01_RS03510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GIY01_RS03515	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GIY01_RS03520	COG0745	RESPONSE REGULATOR receiver
GIY01_RS03530	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GIY01_RS03535	COG0840	transmembrane signaling receptor activity
GIY01_RS03540	COG0840	transmembrane signaling receptor activity
GIY01_RS03545	COG0835	chemotaxis
GIY01_RS03550	COG0643	Histidine kinase
GIY01_RS03550	COG2198	Histidine kinase
GIY01_RS03555	COG1360	Flagellar Motor Protein
GIY01_RS03605	COG0583	DNA-binding transcription factor activity
GIY01_RS03620	COG0583	DNA-binding transcription factor activity
GIY01_RS03635	COG0670	Belongs to the BI1 family
GIY01_RS03665	COG0438	transferase activity, transferring glycosyl groups
GIY01_RS03670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIY01_RS03675	COG2274	protein secretion by the type I secretion system
GIY01_RS03690	COG1832	CoA-binding protein
GIY01_RS03700	COG0210	DNA helicase
GIY01_RS03705	COG3304	Inner membrane component domain
GIY01_RS03710	COG1289	transmembrane transporter activity
GIY01_RS03715	COG3070	regulator of competence-specific genes
GIY01_RS03735	COG1067	ATP-dependent peptidase activity
GIY01_RS03745	COG3130	regulation of translation
GIY01_RS03750	COG3009	Protein conserved in bacteria
GIY01_RS03755	COG3008	intermembrane lipid transfer
GIY01_RS03755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GIY01_RS03760	COG2995	paraquat-inducible protein a
GIY01_RS03765	COG0488	(ABC) transporter
GIY01_RS03775	COG0633	Ferredoxin
GIY01_RS03775	COG3217	Mosc domain protein beta barrel domain protein
GIY01_RS03790	COG0431	NADPH-dependent FMN reductase
GIY01_RS03795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GIY01_RS03800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GIY01_RS03805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GIY01_RS03815	COG0308	aminopeptidase N
GIY01_RS03830	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GIY01_RS03835	COG1448	Aminotransferase
GIY01_RS03840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GIY01_RS03845	COG3108	Peptidase M15
GIY01_RS03850	COG2989	Protein conserved in bacteria
GIY01_RS03860	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GIY01_RS03870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GIY01_RS03875	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GIY01_RS03880	COG3173	Aminoglycoside phosphotransferase
GIY01_RS03890	COG2835	tetraacyldisaccharide 4'-kinase activity
GIY01_RS03895	COG3214	Protein conserved in bacteria
GIY01_RS03910	COG2333	competence protein COMEC
GIY01_RS03910	COG0658	competence protein
GIY01_RS03920	COG0539	negative regulation of cytoplasmic translation
GIY01_RS03945	COG1944	ATP diphosphatase activity
GIY01_RS03950	COG2116	formate transmembrane transporter activity
GIY01_RS03955	COG1882	Formate acetyltransferase
GIY01_RS03960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GIY01_RS03965	COG0477	Major facilitator Superfamily
GIY01_RS03970	COG3302	dmso reductase anchor subunit
GIY01_RS03975	COG0437	4 iron, 4 sulfur cluster binding
GIY01_RS03980	COG0243	molybdopterin cofactor binding
GIY01_RS03990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GIY01_RS04000	COG1674	ftsk spoiiie
GIY01_RS04000	COG1178	ABC-type Fe3 transport system permease component
GIY01_RS04010	COG0492	ferredoxin-NADP+ reductase activity
GIY01_RS04015	COG4988	ABC transporter
GIY01_RS04020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GIY01_RS04035	COG0542	response to heat
GIY01_RS04045	COG1278	Cold shock
GIY01_RS04055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIY01_RS04060	COG3593	DNA synthesis involved in DNA repair
GIY01_RS04070	COG2431	L-lysine efflux transmembrane transporter activity
GIY01_RS04080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GIY01_RS04095	COG0028	Belongs to the TPP enzyme family
GIY01_RS04100	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GIY01_RS04105	COG0702	epimerase
GIY01_RS04110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GIY01_RS04115	COG3023	N-Acetylmuramoyl-L-alanine amidase
GIY01_RS04120	COG3706	GGDEF domain
GIY01_RS04120	COG4251	negative regulation of phosphorylation
GIY01_RS04120	COG5001	Diguanylate cyclase
GIY01_RS04120	COG2203	Gaf domain
GIY01_RS04130	COG2067	long-chain fatty acid transport protein
GIY01_RS04140	COG1126	abc transporter atp-binding protein
GIY01_RS04145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIY01_RS04150	COG4215	(ABC) transporter
GIY01_RS04155	COG4160	amino acid transport
GIY01_RS04160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIY01_RS04165	COG5002	protein histidine kinase activity
GIY01_RS04170	COG0745	RESPONSE REGULATOR receiver
GIY01_RS04175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GIY01_RS04185	COG1177	transmembrane transport
GIY01_RS04190	COG1176	ABC-type spermidine putrescine transport system, permease component I
GIY01_RS04195	COG3842	ATPase activity
GIY01_RS04200	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GIY01_RS04215	COG0778	Nitroreductase
GIY01_RS04250	COG0300	oxidoreductase activity
GIY01_RS04255	COG3226	Transcriptional regulator
GIY01_RS04260	COG0738	Major facilitator superfamily
GIY01_RS04265	COG0561	phosphatase activity
GIY01_RS04270	COG2814	Major facilitator Superfamily
GIY01_RS04280	COG0671	phosphoesterase, PA-phosphatase related
GIY01_RS04285	COG1349	DNA-binding transcription factor activity
GIY01_RS04290	COG1686	Belongs to the peptidase S11 family
GIY01_RS04295	COG0625	glutathione transferase activity
GIY01_RS04300	COG2133	pyrroloquinoline quinone binding
GIY01_RS04325	COG0747	negative chemotaxis
GIY01_RS04335	COG1446	asparaginase
GIY01_RS04340	COG0303	'Molybdopterin
GIY01_RS04345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GIY01_RS04350	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GIY01_RS04355	COG1882	Formate acetyltransferase
GIY01_RS04360	COG0561	phosphatase activity
GIY01_RS04370	COG1609	Transcriptional regulator
GIY01_RS04375	COG2271	Major facilitator Superfamily
GIY01_RS04385	COG0488	(ABC) transporter
GIY01_RS04395	COG1376	ErfK ybiS ycfS ynhG family protein
GIY01_RS04400	COG2188	Transcriptional regulator
GIY01_RS04405	COG2723	6-phospho-beta-galactosidase activity
GIY01_RS04410	COG0667	Aldo Keto reductase
GIY01_RS04415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GIY01_RS04420	COG1321	iron dependent repressor
GIY01_RS04430	COG2194	sulfuric ester hydrolase activity
GIY01_RS04435	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GIY01_RS04450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIY01_RS04455	COG0765	amino acid transport
GIY01_RS04460	COG1126	abc transporter atp-binding protein
GIY01_RS04465	COG0668	transmembrane transport
GIY01_RS04475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GIY01_RS04485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GIY01_RS04495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GIY01_RS04505	COG0513	Belongs to the DEAD box helicase family
GIY01_RS04510	COG1309	transcriptional regulator
GIY01_RS04520	COG1131	(ABC) transporter
GIY01_RS04525	COG0842	Transport permease protein
GIY01_RS04530	COG0842	Transport permease protein
GIY01_RS04540	COG3568	Endonuclease Exonuclease Phosphatase
GIY01_RS04545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GIY01_RS04550	COG0392	lysyltransferase activity
GIY01_RS04555	COG0670	Belongs to the BI1 family
GIY01_RS04560	COG0314	molybdopterin synthase activity
GIY01_RS04565	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GIY01_RS04575	COG0521	Mo-molybdopterin cofactor biosynthetic process
GIY01_RS04595	COG0745	RESPONSE REGULATOR receiver
GIY01_RS04620	COG2226	methyltransferase
GIY01_RS04635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GIY01_RS04640	COG1881	PFAM PEBP family protein
GIY01_RS04675	COG4677	pectinesterase activity
GIY01_RS04685	COG1595	DNA-templated transcription, initiation
GIY01_RS04710	COG0789	Transcriptional regulator
GIY01_RS04715	COG2200	EAL domain
GIY01_RS04740	COG0561	phosphatase activity
GIY01_RS04750	COG4149	molybdate abc transporter
GIY01_RS04755	COG0725	ABC transporter, periplasmic molybdate-binding protein
GIY01_RS04765	COG2005	Transcriptional regulator
GIY01_RS04765	COG3585	molybdate ion transport
GIY01_RS04770	COG1119	ATPase activity
GIY01_RS04775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GIY01_RS04780	COG1085	galactose-1-phosphate uridylyltransferase
GIY01_RS04790	COG2017	converts alpha-aldose to the beta-anomer
GIY01_RS04800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GIY01_RS04810	COG1230	cation diffusion facilitator family transporter
GIY01_RS04820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GIY01_RS04860	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GIY01_RS04865	COG2885	chlorophyll binding
GIY01_RS04875	COG3064	Membrane
GIY01_RS04880	COG0848	biopolymer transport protein
GIY01_RS04885	COG0811	peptide transport
GIY01_RS04890	COG0824	Thioesterase
GIY01_RS04895	COG3790	cyd operon protein YbgE
GIY01_RS04900	COG4890	Cyd operon protein YbgT
GIY01_RS04905	COG1294	oxidase, subunit
GIY01_RS04910	COG1271	oxidase subunit
GIY01_RS04920	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GIY01_RS04930	COG0508	dehydrogenase complex catalyzes the overall conversion of
GIY01_RS04935	COG0567	Dehydrogenase, E1 component
GIY01_RS04940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GIY01_RS04945	COG1053	succinate dehydrogenase
GIY01_RS04950	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GIY01_RS04955	COG2009	succinate dehydrogenase
GIY01_RS04960	COG0372	Belongs to the citrate synthase family
GIY01_RS04990	COG1984	allophanate hydrolase subunit 2
GIY01_RS04995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GIY01_RS05000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GIY01_RS05010	COG0415	Belongs to the DNA photolyase family
GIY01_RS05040	COG2205	protein histidine kinase activity
GIY01_RS05045	COG0745	RESPONSE REGULATOR receiver
GIY01_RS05050	COG0033	Phosphoglucomutase
GIY01_RS05060	COG0596	Alpha beta hydrolase
GIY01_RS05075	COG0735	belongs to the Fur family
GIY01_RS05080	COG0583	DNA-binding transcription factor activity
GIY01_RS05085	COG1053	succinate dehydrogenase
GIY01_RS05130	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GIY01_RS05135	COG1846	Transcriptional regulator
GIY01_RS05135	COG1940	carbohydrate kinase activity
GIY01_RS05140	COG0647	UMP catabolic process
GIY01_RS05145	COG0367	asparagine synthase
GIY01_RS05185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GIY01_RS05195	COG1702	phosphate starvation-inducible protein PhoH
GIY01_RS05220	COG0765	amino acid transport
GIY01_RS05225	COG0765	amino acid transport
GIY01_RS05230	COG1126	abc transporter atp-binding protein
GIY01_RS05235	COG2831	hemolysin activation secretion protein
GIY01_RS05245	COG2888	peptidyl-tyrosine sulfation
GIY01_RS05260	COG1466	dna polymerase III delta subunit
GIY01_RS05270	COG0406	alpha-ribazole phosphatase activity
GIY01_RS05275	COG0799	negative regulation of ribosome biogenesis
GIY01_RS05285	COG0768	penicillin binding
GIY01_RS05290	COG0772	Belongs to the SEDS family
GIY01_RS05295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GIY01_RS05300	COG1686	Belongs to the peptidase S11 family
GIY01_RS05315	COG0583	DNA-binding transcription factor activity
GIY01_RS05330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GIY01_RS05350	COG3069	C4-dicarboxylate transmembrane transporter activity
GIY01_RS05355	COG3719	Belongs to the RNase T2 family
GIY01_RS05360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GIY01_RS05370	COG3634	alkyl hydroperoxide reductase activity
GIY01_RS05380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GIY01_RS05390	COG0583	DNA-binding transcription factor activity
GIY01_RS05395	COG3969	phosphoadenosine phosphosulfate
GIY01_RS05400	COG1475	DNA binding
GIY01_RS05405	COG0436	Aminotransferase
GIY01_RS05415	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GIY01_RS05440	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIY01_RS05445	COG1129	ABC transporter
GIY01_RS05465	COG2879	small protein
GIY01_RS05470	COG1966	Carbon starvation protein
GIY01_RS05480	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS05485	COG3433	isochorismatase activity
GIY01_RS05485	COG1535	isochorismatase
GIY01_RS05490	COG1021	2,3-dihydroxybenzoate-AMP ligase
GIY01_RS05495	COG1169	isochorismate synthase
GIY01_RS05500	COG4592	Periplasmic binding protein
GIY01_RS05515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIY01_RS05520	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIY01_RS05525	COG1120	ATPase activity
GIY01_RS05530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GIY01_RS05530	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GIY01_RS05535	COG3251	PFAM MbtH domain protein
GIY01_RS05540	COG2382	esterase
GIY01_RS05545	COG4771	TonB-dependent receptor
GIY01_RS05550	COG3958	Transketolase
GIY01_RS05555	COG3959	Transketolase, thiamine diphosphate binding domain
GIY01_RS05560	COG2390	Transcriptional regulator
GIY01_RS05565	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GIY01_RS05570	COG1879	ABC-type sugar transport system periplasmic component
GIY01_RS05580	COG1129	ABC transporter
GIY01_RS05585	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIY01_RS05595	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS05615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GIY01_RS05645	COG3698	Phosphodiester glycosidase
GIY01_RS05675	COG2315	Protein conserved in bacteria
GIY01_RS05680	COG0778	Nitroreductase
GIY01_RS05700	COG0477	Major facilitator Superfamily
GIY01_RS05705	COG0668	transmembrane transport
GIY01_RS05710	COG1113	amino acid transport
GIY01_RS05725	COG1252	NADH dehydrogenase
GIY01_RS05735	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS05750	COG0531	amino acid
GIY01_RS05765	COG4680	protein conserved in bacteria
GIY01_RS05805	COG0667	Aldo Keto reductase
GIY01_RS05810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIY01_RS05815	COG1473	amidohydrolase
GIY01_RS05835	COG1566	PFAM secretion protein HlyD family protein
GIY01_RS05850	COG0583	DNA-binding transcription factor activity
GIY01_RS05860	COG0666	response to abiotic stimulus
GIY01_RS05870	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GIY01_RS05875	COG1304	FMN binding
GIY01_RS05880	COG0549	Belongs to the carbamate kinase family
GIY01_RS05885	COG0402	S-adenosylhomocysteine deaminase activity
GIY01_RS05895	COG3104	oligopeptide transport
GIY01_RS05905	COG0531	amino acid
GIY01_RS05910	COG3710	Transcriptional regulator
GIY01_RS05915	COG1902	pentaerythritol trinitrate reductase activity
GIY01_RS05925	COG1560	Kdo2-lipid A biosynthetic process
GIY01_RS05990	COG0583	DNA-binding transcription factor activity
GIY01_RS06035	COG2501	S4 domain
GIY01_RS06045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GIY01_RS06055	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GIY01_RS06060	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GIY01_RS06075	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GIY01_RS06080	COG4181	ATPase activity
GIY01_RS06085	COG2755	lipolytic protein G-D-S-L family
GIY01_RS06090	COG0300	oxidoreductase activity
GIY01_RS06095	COG3118	belongs to the thioredoxin family
GIY01_RS06100	COG0390	transport system, permease component
GIY01_RS06105	COG4619	ABC transporter
GIY01_RS06110	COG0330	HflC and HflK could
GIY01_RS06115	COG1585	Membrane protein implicated in regulation of membrane protease activity
GIY01_RS06130	COG3735	TraB family
GIY01_RS06135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GIY01_RS06145	COG2223	nitrite transmembrane transporter activity
GIY01_RS06150	COG4651	solute:proton antiporter activity
GIY01_RS06150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GIY01_RS06155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIY01_RS06195	COG2832	Protein of unknown function (DUF454)
GIY01_RS06200	COG3923	Primosomal replication protein n
GIY01_RS06210	COG3264	Mechanosensitive ion channel
GIY01_RS06210	COG1196	nuclear chromosome segregation
GIY01_RS06215	COG1309	transcriptional regulator
GIY01_RS06220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIY01_RS06225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GIY01_RS06240	COG0110	maltose O-acetyltransferase activity
GIY01_RS06260	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GIY01_RS06270	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GIY01_RS06275	COG5507	3-demethylubiquinone-9 3-methyltransferase
GIY01_RS06280	COG2364	Membrane
GIY01_RS06310	COG3695	enzyme binding
GIY01_RS06315	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GIY01_RS06320	COG1946	Acyl-CoA thioesterase
GIY01_RS06325	COG0583	DNA-binding transcription factor activity
GIY01_RS06330	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GIY01_RS06335	COG0004	ammonium transporteR
GIY01_RS06340	COG0347	Belongs to the P(II) protein family
GIY01_RS06345	COG1132	(ABC) transporter
GIY01_RS06350	COG1132	(ABC) transporter
GIY01_RS06355	COG1522	sequence-specific DNA binding
GIY01_RS06370	COG4533	DNA binding
GIY01_RS06380	COG0824	Thioesterase
GIY01_RS06385	COG1555	photosystem II stabilization
GIY01_RS06395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GIY01_RS06400	COG0776	regulation of translation
GIY01_RS06405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GIY01_RS06430	COG0271	Belongs to the BolA IbaG family
GIY01_RS06440	COG3056	Lipoprotein
GIY01_RS06460	COG2223	nitrite transmembrane transporter activity
GIY01_RS06465	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GIY01_RS06470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GIY01_RS06475	COG1845	cytochrome c oxidase, subunit III
GIY01_RS06480	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GIY01_RS06495	COG2814	Major facilitator Superfamily
GIY01_RS06535	COG1136	(ABC) transporter
GIY01_RS06550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GIY01_RS06565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GIY01_RS06570	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS06575	COG0736	holo-[acyl-carrier-protein] synthase activity
GIY01_RS06580	COG2831	hemolysin activation secretion protein
GIY01_RS06595	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GIY01_RS06620	COG0142	geranyltranstransferase activity
GIY01_RS06630	COG0667	Aldo Keto reductase
GIY01_RS06635	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GIY01_RS06640	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GIY01_RS06655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GIY01_RS06655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GIY01_RS06665	COG4238	major outer membrane lipoprotein
GIY01_RS06670	COG3248	Nucleoside-binding outer membrane protein
GIY01_RS06685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GIY01_RS06695	COG1862	Preprotein translocase
GIY01_RS06715	COG0450	alkyl hydroperoxide reductase
GIY01_RS06720	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GIY01_RS06730	COG1335	isochorismatase
GIY01_RS06735	COG0583	DNA-binding transcription factor activity
GIY01_RS06740	COG0366	Alpha amylase catalytic
GIY01_RS06765	COG0420	3'-5' exonuclease activity
GIY01_RS06770	COG0419	ATPase involved in DNA repair
GIY01_RS06775	COG1940	carbohydrate kinase activity
GIY01_RS06790	COG4126	flavin adenine dinucleotide binding
GIY01_RS06800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GIY01_RS06805	COG3416	Protein conserved in bacteria
GIY01_RS06815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GIY01_RS06825	COG1785	Belongs to the alkaline phosphatase family
GIY01_RS06860	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GIY01_RS06870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GIY01_RS06875	COG0113	porphobilinogen synthase activity
GIY01_RS06880	COG1943	Transposase
GIY01_RS06895	COG2175	clavaminate synthase activity
GIY01_RS06900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GIY01_RS06905	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GIY01_RS06910	COG4521	taurine ABC transporter
GIY01_RS06915	COG2040	homocysteine
GIY01_RS06920	COG0833	amino acid
GIY01_RS06930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIY01_RS06940	COG0765	amino acid transport
GIY01_RS06945	COG0765	amino acid transport
GIY01_RS06950	COG0583	DNA-binding transcription factor activity
GIY01_RS06955	COG2271	Major facilitator Superfamily
GIY01_RS06975	COG3188	usher protein
GIY01_RS07000	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GIY01_RS07010	COG3639	organic phosphonate transmembrane transporter activity
GIY01_RS07030	COG0791	NLP P60 protein
GIY01_RS07100	COG3121	Chaperone
GIY01_RS07105	COG3188	usher protein
GIY01_RS07125	COG0579	oxidoreductase
GIY01_RS07130	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS07135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GIY01_RS07140	COG1113	amino acid transport
GIY01_RS07145	COG1802	Transcriptional regulator
GIY01_RS07160	COG0583	DNA-binding transcription factor activity
GIY01_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS07185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GIY01_RS07195	COG1596	polysaccharide export
GIY01_RS07215	COG0463	Glycosyl transferase, family 2
GIY01_RS07220	COG0438	transferase activity, transferring glycosyl groups
GIY01_RS07225	COG0438	transferase activity, transferring glycosyl groups
GIY01_RS07225	COG0297	glycogen (starch) synthase activity
GIY01_RS07240	COG1045	serine acetyltransferase
GIY01_RS07260	COG2195	Cleaves the N-terminal amino acid of tripeptides
GIY01_RS07265	COG0454	-acetyltransferase
GIY01_RS07280	COG2991	Protein conserved in bacteria
GIY01_RS07295	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GIY01_RS07300	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GIY01_RS07315	COG3034	peptidoglycan biosynthetic process
GIY01_RS07320	COG0121	glutamine amidotransferase
GIY01_RS07330	COG1960	acyl-CoA dehydrogenase activity
GIY01_RS07335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GIY01_RS07345	COG0583	DNA-binding transcription factor activity
GIY01_RS07355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIY01_RS07365	COG2226	methyltransferase
GIY01_RS07375	COG0741	lytic transglycosylase activity
GIY01_RS07375	COG1388	LysM domain
GIY01_RS07380	COG2226	methyltransferase
GIY01_RS07390	COG2814	Major facilitator Superfamily
GIY01_RS07395	COG0583	DNA-binding transcription factor activity
GIY01_RS07400	COG0656	L-ascorbic acid biosynthetic process
GIY01_RS07435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GIY01_RS07445	COG2011	ABC-type metal ion transport system permease component
GIY01_RS07450	COG1464	Belongs to the NlpA lipoprotein family
GIY01_RS07460	COG1720	tRNA m6t6A37 methyltransferase activity
GIY01_RS07470	COG3015	lipoprotein NlpE involved in copper resistance
GIY01_RS07475	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GIY01_RS07490	COG4568	rho-dependent transcription termination
GIY01_RS07495	COG0037	tRNA processing
GIY01_RS07500	COG0346	lactoylglutathione lyase activity
GIY01_RS07505	COG1982	Orn Lys Arg decarboxylase major
GIY01_RS07560	COG0750	zinc metalloprotease
GIY01_RS07565	COG0575	Belongs to the CDS family
GIY01_RS07575	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GIY01_RS07600	COG0024	Methionine aminopeptidase
GIY01_RS07605	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GIY01_RS07625	COG3835	regulator
GIY01_RS07645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GIY01_RS07650	COG2860	membrane
GIY01_RS07670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIY01_RS07675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GIY01_RS07680	COG1120	ATPase activity
GIY01_RS07685	COG4774	siderophore transport
GIY01_RS07690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GIY01_RS07700	COG1643	Atp-dependent helicase
GIY01_RS07705	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GIY01_RS07730	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GIY01_RS07745	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GIY01_RS07750	COG0726	polysaccharide deacetylase
GIY01_RS07755	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIY01_RS07760	COG0842	Transport permease protein
GIY01_RS07765	COG1131	(ABC) transporter
GIY01_RS07770	COG0288	reversible hydration of carbon dioxide
GIY01_RS07780	COG4993	Dehydrogenase
GIY01_RS07785	COG2132	Multicopper oxidase
GIY01_RS07800	COG0545	Peptidyl-prolyl cis-trans isomerase
GIY01_RS07820	COG1049	propionate catabolic process, 2-methylcitrate cycle
GIY01_RS07825	COG3064	Membrane
GIY01_RS07840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GIY01_RS07845	COG0508	dehydrogenase complex catalyzes the overall conversion of
GIY01_RS07850	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GIY01_RS07855	COG2186	Transcriptional regulator
GIY01_RS07860	COG1113	amino acid transport
GIY01_RS07865	COG2211	Major facilitator Superfamily
GIY01_RS07870	COG3940	Belongs to the glycosyl hydrolase 43 family
GIY01_RS07875	COG3725	Membrane protein required for beta-lactamase induction
GIY01_RS07890	COG4969	Belongs to the N-Me-Phe pilin family
GIY01_RS07895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GIY01_RS07900	COG1459	type II secretion system
GIY01_RS07925	COG0494	nUDIX hydrolase
GIY01_RS07945	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GIY01_RS07950	COG0849	cell division
GIY01_RS07960	COG1181	Belongs to the D-alanine--D-alanine ligase family
GIY01_RS07975	COG0772	Belongs to the SEDS family
GIY01_RS07990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GIY01_RS07995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GIY01_RS08000	COG0768	penicillin binding
GIY01_RS08030	COG0028	Belongs to the TPP enzyme family
GIY01_RS08080	COG0738	Major facilitator superfamily
GIY01_RS08090	COG0583	DNA-binding transcription factor activity
GIY01_RS08095	COG2271	Major facilitator Superfamily
GIY01_RS08100	COG2814	Major facilitator Superfamily
GIY01_RS08120	COG1178	ABC-type Fe3 transport system permease component
GIY01_RS08130	COG0586	Pfam SNARE associated Golgi protein
GIY01_RS08150	COG0235	Class ii aldolase
GIY01_RS08155	COG0417	DNA replication proofreading
GIY01_RS08165	COG0564	pseudouridine synthase activity
GIY01_RS08175	COG3493	citrate carrier protein
GIY01_RS08190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GIY01_RS08195	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GIY01_RS08205	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GIY01_RS08255	COG0505	Belongs to the CarA family
GIY01_RS08320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GIY01_RS08330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GIY01_RS08340	COG0471	metal ion transport
GIY01_RS08345	COG2828	Protein conserved in bacteria
GIY01_RS08355	COG0583	DNA-binding transcription factor activity
GIY01_RS08370	COG1047	Peptidyl-prolyl cis-trans
GIY01_RS08375	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GIY01_RS08385	COG0196	riboflavin kinase activity
GIY01_RS08400	COG0583	DNA-binding transcription factor activity
GIY01_RS08420	COG3121	Chaperone
GIY01_RS08425	COG3539	Fimbrial protein
GIY01_RS08440	COG3188	usher protein
GIY01_RS08450	COG3539	Fimbrial protein
GIY01_RS08455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GIY01_RS08490	COG0583	DNA-binding transcription factor activity
GIY01_RS08505	COG1584	GPR1 FUN34 yaaH family protein
GIY01_RS08510	COG0477	Major facilitator Superfamily
GIY01_RS08515	COG0521	Mo-molybdopterin cofactor biosynthetic process
GIY01_RS08520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GIY01_RS08525	COG1115	amino acid carrier protein
GIY01_RS08535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GIY01_RS08545	COG0460	homoserine dehydrogenase
GIY01_RS08545	COG0527	aspartate kinase activity
GIY01_RS08555	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GIY01_RS08565	COG0745	RESPONSE REGULATOR receiver
GIY01_RS08570	COG4452	Inner membrane protein CreD
GIY01_RS08575	COG2205	protein histidine kinase activity
GIY01_RS08580	COG0745	RESPONSE REGULATOR receiver
GIY01_RS08585	COG3045	CreA protein
GIY01_RS08590	COG3708	Transcriptional regulator
GIY01_RS08590	COG2207	Transcriptional regulator
GIY01_RS08610	COG0741	lytic transglycosylase activity
GIY01_RS08615	COG0488	(ABC) transporter
GIY01_RS08625	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GIY01_RS08630	COG0560	Phosphoserine phosphatase
GIY01_RS08635	COG3726	membrane protein affecting hemolysin expression
GIY01_RS08665	COG0084	hydrolase, TatD family'
GIY01_RS08670	COG4667	esterase of the alpha-beta hydrolase superfamily
GIY01_RS08675	COG5487	UPF0391 membrane protein
GIY01_RS08680	COG2823	Periplasmic or secreted lipoprotein
GIY01_RS08690	COG1011	Hydrolase
GIY01_RS08695	COG0456	acetyltransferase
GIY01_RS08700	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GIY01_RS08730	COG3706	GGDEF domain
GIY01_RS08735	COG4114	ferric iron reductase
GIY01_RS08740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GIY01_RS08745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GIY01_RS08750	COG2197	response regulator
GIY01_RS08755	COG2197	response regulator
GIY01_RS08770	COG2966	Psort location CytoplasmicMembrane, score
GIY01_RS08785	COG1484	DNA-dependent DNA replication
GIY01_RS08810	COG1737	Transcriptional regulator
GIY01_RS08810	COG0837	glucose binding
GIY01_RS08815	COG0800	Aldolase
GIY01_RS08820	COG3734	2-keto-3-deoxy-galactonokinase
GIY01_RS08835	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GIY01_RS08850	COG0531	amino acid
GIY01_RS08855	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS08860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GIY01_RS08875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GIY01_RS08875	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GIY01_RS08895	COG0179	Fumarylacetoacetate (FAA) hydrolase
GIY01_RS08905	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS08910	COG3384	dioxygenase
GIY01_RS08920	COG3971	2-oxopent-4-enoate hydratase activity
GIY01_RS08940	COG2368	4-hydroxyphenylacetate
GIY01_RS08945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GIY01_RS08965	COG3210	domain, Protein
GIY01_RS08995	COG2831	hemolysin activation secretion protein
GIY01_RS09000	COG1966	Carbon starvation protein
GIY01_RS09005	COG2879	small protein
GIY01_RS09010	COG0523	cobalamin synthesis protein
GIY01_RS09015	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS09020	COG2733	membrane
GIY01_RS09025	COG2814	Major facilitator Superfamily
GIY01_RS09035	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GIY01_RS09040	COG1924	4 iron, 4 sulfur cluster binding
GIY01_RS09050	COG1473	amidohydrolase
GIY01_RS09055	COG0700	Nucleoside recognition
GIY01_RS09060	COG3366	ferrous iron transmembrane transporter activity
GIY01_RS09075	COG1566	PFAM secretion protein HlyD family protein
GIY01_RS09085	COG5457	Domain of unknown function (DUF1127)
GIY01_RS09090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GIY01_RS09100	COG0531	amino acid
GIY01_RS09120	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIY01_RS09120	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIY01_RS09125	COG3715	PTS system
GIY01_RS09130	COG3716	PTS system mannose fructose sorbose family IID component
GIY01_RS09175	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS09175	COG1454	alcohol dehydrogenase
GIY01_RS09190	COG1882	Formate acetyltransferase
GIY01_RS09195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GIY01_RS09205	COG4869	propanediol catabolic process
GIY01_RS09230	COG3706	GGDEF domain
GIY01_RS09235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIY01_RS09240	COG0842	Transport permease protein
GIY01_RS09240	COG1129	ABC transporter
GIY01_RS09245	COG0842	Transport permease protein
GIY01_RS09280	COG2850	peptidyl-arginine hydroxylation
GIY01_RS09285	COG5002	protein histidine kinase activity
GIY01_RS09290	COG0745	RESPONSE REGULATOR receiver
GIY01_RS09295	COG1538	Outer membrane efflux protein
GIY01_RS09300	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIY01_RS09310	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GIY01_RS09435	COG4974	Belongs to the 'phage' integrase family
GIY01_RS09455	COG0582	viral genome integration into host DNA
GIY01_RS09465	COG0288	reversible hydration of carbon dioxide
GIY01_RS09470	COG0659	secondary active sulfate transmembrane transporter activity
GIY01_RS09475	COG1064	alcohol dehydrogenase
GIY01_RS09480	COG1175	transmembrane transport
GIY01_RS09485	COG0395	ABC-type sugar transport system, permease component
GIY01_RS09490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GIY01_RS09495	COG3842	ATPase activity
GIY01_RS09505	COG2814	Major facilitator Superfamily
GIY01_RS09515	COG1082	Xylose isomerase domain protein TIM barrel
GIY01_RS09525	COG3962	Belongs to the TPP enzyme family
GIY01_RS09535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIY01_RS09540	COG0837	glucose binding
GIY01_RS09540	COG1737	Transcriptional regulator
GIY01_RS09545	COG3718	enzyme involved in inositol metabolism
GIY01_RS09560	COG0433	COG0433 Predicted ATPase
GIY01_RS09565	COG0795	lipopolysaccharide-transporting ATPase activity
GIY01_RS09570	COG0795	lipopolysaccharide-transporting ATPase activity
GIY01_RS09580	COG2927	DNA polymerase III (CHI subunit)
GIY01_RS09585	COG0525	valine-tRNA ligase activity
GIY01_RS09605	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GIY01_RS09610	COG2731	YhcH YjgK YiaL family protein
GIY01_RS09630	COG0251	oxidation-reduction process
GIY01_RS09635	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GIY01_RS09650	COG1263	PTS System
GIY01_RS09650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIY01_RS09655	COG0366	Alpha amylase catalytic
GIY01_RS09660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GIY01_RS09665	COG1486	melibiose metabolic process
GIY01_RS09685	COG0602	queuosine metabolic process
GIY01_RS09690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIY01_RS09690	COG3711	transcriptional antiterminator
GIY01_RS09695	COG2706	6-phosphogluconolactonase activity
GIY01_RS09710	COG3964	amidohydrolase
GIY01_RS09745	COG0312	modulator of DNA gyrase
GIY01_RS09760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GIY01_RS09770	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIY01_RS09775	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIY01_RS09780	COG1129	ABC transporter
GIY01_RS09785	COG1879	ABC-type sugar transport system periplasmic component
GIY01_RS09795	COG2105	PFAM AIG2 family protein
GIY01_RS09800	COG2911	Protein conserved in bacteria
GIY01_RS09805	COG0729	surface antigen
GIY01_RS09815	COG1253	flavin adenine dinucleotide binding
GIY01_RS09825	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GIY01_RS09840	COG1733	regulation of RNA biosynthetic process
GIY01_RS09845	COG0702	epimerase
GIY01_RS09855	COG0697	spore germination
GIY01_RS09865	COG1113	amino acid transport
GIY01_RS09870	COG0545	Peptidyl-prolyl cis-trans isomerase
GIY01_RS09875	COG3061	Opacity-associated protein A
GIY01_RS09885	COG0359	binds to the 23S rRNA
GIY01_RS09890	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GIY01_RS09895	COG2965	DNA replication, synthesis of RNA primer
GIY01_RS09955	COG1073	alpha beta
GIY01_RS09960	COG3650	response to hydrogen peroxide
GIY01_RS09970	COG1960	acyl-CoA dehydrogenase activity
GIY01_RS09975	COG0477	Major facilitator Superfamily
GIY01_RS09980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GIY01_RS09985	COG0557	exoribonuclease II activity
GIY01_RS10000	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GIY01_RS10010	COG0330	HflC and HflK could
GIY01_RS10015	COG0330	HflC and HflK could
GIY01_RS10020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GIY01_RS10040	COG0860	N-Acetylmuramoyl-L-alanine amidase
GIY01_RS10045	COG0802	atpase or kinase
GIY01_RS10050	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GIY01_RS10050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GIY01_RS10055	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GIY01_RS10075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIY01_RS10080	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GIY01_RS10095	COG3264	Mechanosensitive ion channel
GIY01_RS10095	COG1511	domain protein
GIY01_RS10115	COG1053	succinate dehydrogenase
GIY01_RS10120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GIY01_RS10140	COG2076	Multidrug Resistance protein
GIY01_RS10145	COG5510	response to toxic substance
GIY01_RS10160	COG1509	lysine 2,3-aminomutase activity
GIY01_RS10205	COG0459	protein refolding
GIY01_RS10215	COG0531	amino acid
GIY01_RS10220	COG3030	protein affecting phage T7 exclusion by the F plasmid
GIY01_RS10225	COG1027	Aspartate ammonia-lyase
GIY01_RS10230	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GIY01_RS10245	COG1309	transcriptional regulator
GIY01_RS10295	COG0457	Tetratricopeptide repeat
GIY01_RS10300	COG1649	PFAM Uncharacterised BCR, COG1649
GIY01_RS10300	COG0726	polysaccharide deacetylase
GIY01_RS10305	COG1215	transferase activity, transferring glycosyl groups
GIY01_RS10320	COG0861	Integral membrane protein TerC family
GIY01_RS10355	COG1486	melibiose metabolic process
GIY01_RS10360	COG2169	Transcriptional regulator
GIY01_RS10375	COG2824	Alkylphosphonate utilization operon protein PhnA
GIY01_RS10380	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GIY01_RS10410	COG3624	Phosphonate C-P lyase system protein PhnG
GIY01_RS10415	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GIY01_RS10420	COG3626	phosphonate metabolism
GIY01_RS10425	COG3627	carbon phosphorus lyase activity
GIY01_RS10430	COG4107	phosphonate C-P lyase system protein PhnK
GIY01_RS10435	COG4778	phosphonate C-P lyase system protein PhnL
GIY01_RS10440	COG3454	Phosphonate metabolism
GIY01_RS10450	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GIY01_RS10460	COG0784	Response regulator, receiver
GIY01_RS10460	COG4191	Histidine kinase
GIY01_RS10465	COG1129	ABC transporter
GIY01_RS10470	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIY01_RS10495	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GIY01_RS10500	COG1301	dicarboxylic acid transport
GIY01_RS10505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GIY01_RS10510	COG3162	membrane
GIY01_RS10520	COG3539	Fimbrial protein
GIY01_RS10525	COG3539	Fimbrial protein
GIY01_RS10540	COG3539	Fimbrial protein
GIY01_RS10545	COG1346	cytolysis
GIY01_RS10555	COG0583	DNA-binding transcription factor activity
GIY01_RS10560	COG0025	NhaP-type Na H and K H
GIY01_RS10565	COG2252	PERMEase
GIY01_RS10570	COG0625	glutathione transferase activity
GIY01_RS10575	COG0789	Transcriptional regulator
GIY01_RS10585	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GIY01_RS10600	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GIY01_RS10630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GIY01_RS10645	COG2315	Protein conserved in bacteria
GIY01_RS10650	COG0432	Pfam Uncharacterised protein family UPF0047
GIY01_RS10660	COG1448	Aminotransferase
GIY01_RS10665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GIY01_RS10670	COG0305	Participates in initiation and elongation during chromosome replication
GIY01_RS10685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GIY01_RS10695	COG0735	belongs to the Fur family
GIY01_RS10700	COG3237	CsbD-like
GIY01_RS10705	COG0534	Mate efflux family protein
GIY01_RS10715	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GIY01_RS10740	COG4580	involved in the transport of maltose and maltodextrins
GIY01_RS10785	COG0251	oxidation-reduction process
GIY01_RS10790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GIY01_RS10800	COG0527	aspartate kinase activity
GIY01_RS10825	COG1187	pseudouridine synthase activity
GIY01_RS10840	COG1283	sodium-dependent phosphate transmembrane transporter activity
GIY01_RS10845	COG1410	methionine synthase
GIY01_RS10845	COG0646	methionine synthase
GIY01_RS10865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GIY01_RS10905	COG0151	Belongs to the GarS family
GIY01_RS10915	COG4191	Histidine kinase
GIY01_RS10955	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GIY01_RS10970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GIY01_RS10975	COG2104	thiamine diphosphate biosynthetic process
GIY01_RS10990	COG3706	GGDEF domain
GIY01_RS11000	COG1447	Phosphotransferase system cellobiose-specific component IIA
GIY01_RS11005	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GIY01_RS11040	COG0250	Participates in transcription elongation, termination and antitermination
GIY01_RS11145	COG0583	DNA-binding transcription factor activity
GIY01_RS11160	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GIY01_RS11175	COG3443	Belongs to the bacterial solute-binding protein 9 family
GIY01_RS11180	COG2207	Transcriptional regulator
GIY01_RS11190	COG0371	Dehydrogenase
GIY01_RS11195	COG0697	spore germination
GIY01_RS11205	COG0527	aspartate kinase activity
GIY01_RS11205	COG0460	homoserine dehydrogenase
GIY01_RS11210	COG0626	cystathionine gamma-synthase activity
GIY01_RS11225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GIY01_RS11230	COG1609	Transcriptional regulator
GIY01_RS11235	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GIY01_RS11250	COG1575	Belongs to the MenA family. Type 1 subfamily
GIY01_RS11295	COG0745	RESPONSE REGULATOR receiver
GIY01_RS11300	COG2205	protein histidine kinase activity
GIY01_RS11305	COG2258	MOSC domain
GIY01_RS11310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GIY01_RS11350	COG1454	alcohol dehydrogenase
GIY01_RS11365	COG2731	YhcH YjgK YiaL family protein
GIY01_RS11370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GIY01_RS11375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIY01_RS11385	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GIY01_RS11410	COG0437	4 iron, 4 sulfur cluster binding
GIY01_RS11415	COG2864	formate dehydrogenase
GIY01_RS11425	COG0657	acetylesterase activity
GIY01_RS11430	COG0456	acetyltransferase
GIY01_RS11445	COG1011	Hydrolase
GIY01_RS11460	COG3852	Histidine kinase
GIY01_RS11470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GIY01_RS11495	COG0204	Acyl-transferase
GIY01_RS11505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GIY01_RS11510	COG3084	Protein conserved in bacteria
GIY01_RS11520	COG1763	Mo-molybdopterin cofactor biosynthetic process
GIY01_RS11545	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GIY01_RS11595	COG0805	protein transport
GIY01_RS11605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GIY01_RS11615	COG3165	ubiquinone biosynthetic process from chorismate
GIY01_RS11645	COG0583	DNA-binding transcription factor activity
GIY01_RS11650	COG0697	spore germination
GIY01_RS11655	COG0561	phosphatase activity
GIY01_RS11660	COG2267	carboxylic ester hydrolase activity
GIY01_RS11665	COG1280	lysine exporter protein (LysE YggA)
GIY01_RS11675	COG1280	lysine exporter protein (LysE YggA)
GIY01_RS11690	COG2050	protein possibly involved in aromatic compounds catabolism
GIY01_RS11705	COG0210	DNA helicase
GIY01_RS11710	COG1011	Hydrolase
GIY01_RS11740	COG3072	Adenylate cyclase
GIY01_RS11750	COG1587	Uroporphyrinogen-III synthase
GIY01_RS11755	COG2959	enzyme of heme biosynthesis
GIY01_RS11760	COG3071	HemY protein
GIY01_RS11810	COG2244	polysaccharide biosynthetic process
GIY01_RS11815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GIY01_RS11820	COG0456	acetyltransferase
GIY01_RS11825	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GIY01_RS11830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GIY01_RS11840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GIY01_RS11845	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GIY01_RS11850	COG3118	belongs to the thioredoxin family
GIY01_RS11865	COG0583	DNA-binding transcription factor activity
GIY01_RS11875	COG1811	Na channel or pump
GIY01_RS11885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GIY01_RS11890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GIY01_RS11900	COG0583	DNA-binding transcription factor activity
GIY01_RS11905	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GIY01_RS11915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GIY01_RS11920	COG3978	acetolactate synthase activity
GIY01_RS11935	COG0606	chelatase, subunit chli
GIY01_RS11940	COG3085	chromosome segregation
GIY01_RS11985	COG2186	Transcriptional regulator
GIY01_RS11990	COG0477	Major facilitator Superfamily
GIY01_RS11995	COG1609	Transcriptional regulator
GIY01_RS12000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIY01_RS12010	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIY01_RS12015	COG1129	ABC transporter
GIY01_RS12045	COG1522	sequence-specific DNA binding
GIY01_RS12050	COG0716	FMN binding
GIY01_RS12065	COG3312	ion transport
GIY01_RS12100	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GIY01_RS12105	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GIY01_RS12115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GIY01_RS12125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GIY01_RS12130	COG0573	inorganic phosphate transmembrane transporter activity
GIY01_RS12135	COG0581	inorganic phosphate transmembrane transporter activity
GIY01_RS12145	COG0704	Plays a role in the regulation of phosphate uptake
GIY01_RS12160	COG2382	esterase
GIY01_RS12165	COG0363	glucosamine-6-phosphate deaminase activity
GIY01_RS12170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GIY01_RS12175	COG2252	PERMEase
GIY01_RS12180	COG0431	NADPH-dependent FMN reductase
GIY01_RS12185	COG2091	lysine biosynthetic process via aminoadipic acid
GIY01_RS12215	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GIY01_RS12225	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GIY01_RS12235	COG0592	DNA-directed DNA polymerase activity
GIY01_RS12245	COG0187	DNA topoisomerase II activity
GIY01_RS12250	COG0561	phosphatase activity
GIY01_RS12265	COG2186	Transcriptional regulator
GIY01_RS12270	COG3734	2-keto-3-deoxy-galactonokinase
GIY01_RS12275	COG0800	Aldolase
GIY01_RS12285	COG2271	Major facilitator Superfamily
GIY01_RS12290	COG0823	Involved in the tonB-independent uptake of proteins
GIY01_RS12295	COG5645	(Lipo)protein
GIY01_RS12330	COG2149	membrane
GIY01_RS12350	COG2610	gluconate transmembrane transporter activity
GIY01_RS12355	COG0583	DNA-binding transcription factor activity
GIY01_RS12360	COG2814	Major facilitator Superfamily
GIY01_RS12385	COG0028	Belongs to the TPP enzyme family
GIY01_RS12390	COG0440	acetolactate synthase activity
GIY01_RS12395	COG2197	response regulator
GIY01_RS12405	COG2271	Major facilitator Superfamily
GIY01_RS12445	COG2188	Transcriptional regulator
GIY01_RS12475	COG4580	involved in the transport of maltose and maltodextrins
GIY01_RS12480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GIY01_RS12480	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GIY01_RS12490	COG1609	Transcriptional regulator
GIY01_RS12505	COG0697	spore germination
GIY01_RS12565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GIY01_RS12580	COG1263	PTS System
GIY01_RS12580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIY01_RS12585	COG1464	Belongs to the NlpA lipoprotein family
GIY01_RS12595	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GIY01_RS12605	COG1064	alcohol dehydrogenase
GIY01_RS12610	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GIY01_RS12650	COG2211	Major facilitator Superfamily
GIY01_RS12655	COG1501	Belongs to the glycosyl hydrolase 31 family
GIY01_RS12660	COG3711	transcriptional antiterminator
GIY01_RS12665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIY01_RS12665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIY01_RS12665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIY01_RS12670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIY01_RS12675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIY01_RS12675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIY01_RS12685	COG0191	fructose-bisphosphate aldolase activity
GIY01_RS12690	COG1940	carbohydrate kinase activity
GIY01_RS12705	COG1486	melibiose metabolic process
GIY01_RS12710	COG1263	PTS System
GIY01_RS12710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIY01_RS12715	COG2982	Protein involved in outer membrane biogenesis
GIY01_RS12720	COG2233	PERMEase
GIY01_RS12725	COG0786	glutamate:sodium symporter activity
GIY01_RS12740	COG3074	FtsZ-dependent cytokinesis
GIY01_RS12745	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GIY01_RS12770	COG3152	Membrane
GIY01_RS12780	COG1494	fructose-1,6-bisphosphatase
GIY01_RS12790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GIY01_RS12795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GIY01_RS12805	COG0194	GDP metabolic process
GIY01_RS12815	COG2860	membrane
GIY01_RS12820	COG1561	YicC-like family, N-terminal region
GIY01_RS12845	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GIY01_RS12855	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GIY01_RS12880	COG1519	Transferase
GIY01_RS12885	COG1216	Glycosyl transferase, family 2
GIY01_RS12900	COG0859	PFAM glycosyl transferase family 9
GIY01_RS12925	COG0859	PFAM glycosyl transferase family 9
GIY01_RS12940	COG0156	8-amino-7-oxononanoate synthase activity
GIY01_RS12955	COG0463	Glycosyl transferase, family 2
GIY01_RS12960	COG2861	carbohydrate metabolic process
GIY01_RS12965	COG4942	peptidase
GIY01_RS12975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GIY01_RS12980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GIY01_RS13000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GIY01_RS13010	COG2186	Transcriptional regulator
GIY01_RS13030	COG3722	fumarate hydratase activity
GIY01_RS13050	COG1566	PFAM secretion protein HlyD family protein
GIY01_RS13055	COG0625	glutathione transferase activity
GIY01_RS13065	COG3276	selenocysteine insertion sequence binding
GIY01_RS13070	COG1454	alcohol dehydrogenase
GIY01_RS13075	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIY01_RS13080	COG3977	Valine--pyruvate aminotransferase
GIY01_RS13085	COG0366	Alpha amylase catalytic
GIY01_RS13090	COG2992	FlgJ-related protein
GIY01_RS13095	COG2207	Transcriptional regulator
GIY01_RS13095	COG1609	Transcriptional regulator
GIY01_RS13100	COG4214	carbohydrate transport
GIY01_RS13110	COG4213	ABC transporter substrate-binding protein
GIY01_RS13120	COG1070	Carbohydrate kinase
GIY01_RS13125	COG4682	membrane
GIY01_RS13130	COG3274	enterobacterial common antigen metabolic process
GIY01_RS13155	COG1278	Cold shock
GIY01_RS13160	COG2944	sequence-specific DNA binding
GIY01_RS13165	COG2814	Major facilitator Superfamily
GIY01_RS13185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIY01_RS13195	COG1609	Transcriptional regulator
GIY01_RS13200	COG2885	chlorophyll binding
GIY01_RS13205	COG0243	molybdopterin cofactor binding
GIY01_RS13210	COG0456	acetyltransferase
GIY01_RS13215	COG2818	Glycosylase
GIY01_RS13220	COG5571	outer membrane autotransporter
GIY01_RS13225	COG2223	nitrite transmembrane transporter activity
GIY01_RS13245	COG0747	negative chemotaxis
GIY01_RS13250	COG0601	transmembrane transport
GIY01_RS13255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GIY01_RS13260	COG0444	Belongs to the ABC transporter superfamily
GIY01_RS13265	COG4608	Belongs to the ABC transporter superfamily
GIY01_RS13280	COG2194	sulfuric ester hydrolase activity
GIY01_RS13310	COG1215	transferase activity, transferring glycosyl groups
GIY01_RS13315	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GIY01_RS13320	COG3118	belongs to the thioredoxin family
GIY01_RS13320	COG0457	Tetratricopeptide repeat
GIY01_RS13325	COG2200	EAL domain
GIY01_RS13325	COG2199	diguanylate cyclase activity
GIY01_RS13335	COG0612	Peptidase, M16
GIY01_RS13345	COG2982	Protein involved in outer membrane biogenesis
GIY01_RS13350	COG0477	Major facilitator Superfamily
GIY01_RS13355	COG1295	ribonuclease BN
GIY01_RS13360	COG0583	DNA-binding transcription factor activity
GIY01_RS13365	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS13370	COG2197	response regulator
GIY01_RS13380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GIY01_RS13390	COG1454	alcohol dehydrogenase
GIY01_RS13395	COG0625	glutathione transferase activity
GIY01_RS13400	COG1609	Transcriptional regulator
GIY01_RS13405	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GIY01_RS13410	COG2610	gluconate transmembrane transporter activity
GIY01_RS13420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GIY01_RS13425	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GIY01_RS13445	COG0589	response to stress
GIY01_RS13455	COG0306	phosphate transporter
GIY01_RS13460	COG2081	HI0933 family
GIY01_RS13465	COG2239	Acts as a magnesium transporter
GIY01_RS13495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GIY01_RS13500	COG0601	transmembrane transport
GIY01_RS13505	COG0747	negative chemotaxis
GIY01_RS13515	COG3479	Phenolic acid decarboxylase
GIY01_RS13555	COG2091	lysine biosynthetic process via aminoadipic acid
GIY01_RS13560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GIY01_RS13565	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS13575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GIY01_RS13610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GIY01_RS13610	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GIY01_RS13620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GIY01_RS13640	COG0477	Major facilitator Superfamily
GIY01_RS13650	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GIY01_RS13665	COG3714	YhhN family
GIY01_RS13675	COG3776	membrane
GIY01_RS13680	COG0742	ribosomal rna small subunit methyltransferase
GIY01_RS13685	COG0552	protein localization to endoplasmic reticulum
GIY01_RS13690	COG2884	Cell division ATP-binding protein ftsE
GIY01_RS13695	COG2177	Part of the ABC transporter FtsEX involved in
GIY01_RS13705	COG0683	leucine binding
GIY01_RS13710	COG0456	acetyltransferase
GIY01_RS13720	COG0683	leucine binding
GIY01_RS13725	COG0559	Belongs to the binding-protein-dependent transport system permease family
GIY01_RS13735	COG0411	ABC transporter
GIY01_RS13775	COG0584	glycerophosphoryl diester phosphodiesterase
GIY01_RS13785	COG0405	Gamma-glutamyltransferase
GIY01_RS13790	COG1247	-acetyltransferase
GIY01_RS13800	COG0673	inositol 2-dehydrogenase activity
GIY01_RS13805	COG1741	Belongs to the pirin family
GIY01_RS13810	COG1609	Transcriptional regulator
GIY01_RS13815	COG3265	gluconokinase activity
GIY01_RS13820	COG2610	gluconate transmembrane transporter activity
GIY01_RS13825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GIY01_RS13850	COG0058	SHG alpha-glucan phosphorylase activity
GIY01_RS13855	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GIY01_RS13870	COG1349	DNA-binding transcription factor activity
GIY01_RS13880	COG0058	SHG alpha-glucan phosphorylase activity
GIY01_RS13885	COG1640	4-alpha-glucanotransferase
GIY01_RS13890	COG2610	gluconate transmembrane transporter activity
GIY01_RS13900	COG1040	competence protein
GIY01_RS13925	COG1918	ferrous iron import across plasma membrane
GIY01_RS13930	COG2183	response to ionizing radiation
GIY01_RS13935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GIY01_RS13945	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS13950	COG0179	Fumarylacetoacetate (FAA) hydrolase
GIY01_RS13955	COG4948	Mandelate Racemase Muconate Lactonizing
GIY01_RS13970	COG3254	rhamnose metabolic process
GIY01_RS13975	COG0738	Major facilitator superfamily
GIY01_RS14000	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GIY01_RS14005	COG1011	Hydrolase
GIY01_RS14015	COG0494	nUDIX hydrolase
GIY01_RS14035	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GIY01_RS14060	COG4796	Type ii and iii secretion system protein
GIY01_RS14075	COG3266	domain, Protein
GIY01_RS14080	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GIY01_RS14085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GIY01_RS14105	COG2146	nitrite reductase [NAD(P)H] activity
GIY01_RS14110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GIY01_RS14115	COG0402	S-adenosylhomocysteine deaminase activity
GIY01_RS14120	COG0738	Major facilitator superfamily
GIY01_RS14135	COG2184	nucleotidyltransferase activity
GIY01_RS14145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GIY01_RS14150	COG1289	transmembrane transporter activity
GIY01_RS14160	COG1765	OsmC-like protein
GIY01_RS14165	COG3954	Phosphoribulokinase
GIY01_RS14175	COG0429	hydrolase of the alpha beta-hydrolase fold
GIY01_RS14180	COG0488	(ABC) transporter
GIY01_RS14195	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GIY01_RS14200	COG1047	Peptidyl-prolyl cis-trans
GIY01_RS14210	COG0545	Peptidyl-prolyl cis-trans isomerase
GIY01_RS14270	COG0051	transcription antitermination factor activity, RNA binding
GIY01_RS14295	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GIY01_RS14310	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GIY01_RS14375	COG0201	protein transport
GIY01_RS14390	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GIY01_RS14415	COG0789	Transcriptional regulator
GIY01_RS14420	COG3036	rescue of stalled ribosome
GIY01_RS14450	COG0758	DNA mediated transformation
GIY01_RS14460	COG0551	DNA topoisomerase type I activity
GIY01_RS14480	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GIY01_RS14515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GIY01_RS14520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GIY01_RS14525	COG1309	transcriptional regulator
GIY01_RS14545	COG4145	pantothenate transmembrane transporter activity
GIY01_RS14550	COG3924	membrane
GIY01_RS14555	COG0439	Biotin carboxylase
GIY01_RS14560	COG0511	ligase activity, forming carbon-carbon bonds
GIY01_RS14565	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GIY01_RS14580	COG0604	alcohol dehydrogenase
GIY01_RS14585	COG2200	EAL domain
GIY01_RS14585	COG2199	diguanylate cyclase activity
GIY01_RS14590	COG1077	Cell shape determining protein MreB Mrl
GIY01_RS14595	COG1792	Involved in formation and maintenance of cell shape
GIY01_RS14600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GIY01_RS14615	COG3164	Protein of unknown function
GIY01_RS14620	COG0312	modulator of DNA gyrase
GIY01_RS14625	COG0583	DNA-binding transcription factor activity
GIY01_RS14640	COG1289	transmembrane transporter activity
GIY01_RS14645	COG2732	(Barnase) inhibitor
GIY01_RS14680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GIY01_RS14685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GIY01_RS14690	COG3105	Protein conserved in bacteria
GIY01_RS14695	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GIY01_RS14710	COG0625	glutathione transferase activity
GIY01_RS14715	COG2969	positive regulation of protein catabolic process
GIY01_RS14720	COG0493	'glutamate synthase
GIY01_RS14725	COG0067	glutamate synthase
GIY01_RS14725	COG0069	glutamate synthase activity
GIY01_RS14725	COG0070	glutamate synthase
GIY01_RS14730	COG1242	4 iron, 4 sulfur cluster binding
GIY01_RS14735	COG0784	Response regulator, receiver
GIY01_RS14735	COG2198	Histidine kinase
GIY01_RS14735	COG5002	protein histidine kinase activity
GIY01_RS14740	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GIY01_RS14745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GIY01_RS14750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIY01_RS14760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIY01_RS14765	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GIY01_RS14770	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GIY01_RS14775	COG1137	ATPase activity
GIY01_RS14780	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GIY01_RS14785	COG3117	lipopolysaccharide transmembrane transporter activity
GIY01_RS14790	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GIY01_RS14800	COG0530	calcium, potassium:sodium antiporter activity
GIY01_RS14805	COG1127	ABC transporter
GIY01_RS14810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GIY01_RS14815	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GIY01_RS14820	COG2854	intermembrane phospholipid transfer
GIY01_RS14825	COG3113	response to antibiotic
GIY01_RS14830	COG5007	Belongs to the BolA IbaG family
GIY01_RS14840	COG3423	Transcriptional regulator
GIY01_RS14845	COG0142	geranyltranstransferase activity
GIY01_RS14860	COG0697	spore germination
GIY01_RS14870	COG2027	D-alanyl-D-alanine carboxypeptidase
GIY01_RS14880	COG1534	Rna-binding protein
GIY01_RS14890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GIY01_RS14905	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GIY01_RS14945	COG0195	Participates in both transcription termination and antitermination
GIY01_RS14990	COG0814	amino acid
GIY01_RS14995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GIY01_RS15000	COG0826	peptidase U32
GIY01_RS15005	COG0826	peptidase U32
GIY01_RS15010	COG3154	lipid carrier protein
GIY01_RS15015	COG3153	acetyltransferase
GIY01_RS15045	COG0693	protein deglycase activity
GIY01_RS15050	COG0702	epimerase
GIY01_RS15055	COG0701	Predicted permease
GIY01_RS15060	COG2823	Periplasmic or secreted lipoprotein
GIY01_RS15080	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GIY01_RS15095	COG2222	sugar isomerase
GIY01_RS15100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GIY01_RS15105	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIY01_RS15110	COG3716	PTS system mannose fructose sorbose family IID component
GIY01_RS15120	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIY01_RS15130	COG1349	DNA-binding transcription factor activity
GIY01_RS15135	COG2721	sulfolactate sulfo-lyase activity
GIY01_RS15145	COG2084	Dehydrogenase
GIY01_RS15150	COG1929	Belongs to the glycerate kinase type-1 family
GIY01_RS15160	COG0668	transmembrane transport
GIY01_RS15175	COG1741	Belongs to the pirin family
GIY01_RS15180	COG0583	DNA-binding transcription factor activity
GIY01_RS15185	COG3152	Membrane
GIY01_RS15190	COG0435	Glutathione S-transferase
GIY01_RS15195	COG2259	Doxx family
GIY01_RS15210	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GIY01_RS15215	COG4575	ribosome binding
GIY01_RS15220	COG1422	Protein of unknown function (DUF1090)
GIY01_RS15230	COG0586	Pfam SNARE associated Golgi protein
GIY01_RS15235	COG2186	Transcriptional regulator
GIY01_RS15240	COG2271	Major facilitator Superfamily
GIY01_RS15250	COG2721	sulfolactate sulfo-lyase activity
GIY01_RS15260	COG0861	Integral membrane protein TerC family
GIY01_RS15265	COG0673	inositol 2-dehydrogenase activity
GIY01_RS15270	COG1451	nucleotide metabolic process
GIY01_RS15280	COG0446	pyridine nucleotide-disulphide oxidoreductase
GIY01_RS15280	COG1902	pentaerythritol trinitrate reductase activity
GIY01_RS15325	COG3408	Glycogen debranching enzyme
GIY01_RS15325	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GIY01_RS15335	COG0531	amino acid
GIY01_RS15340	COG0531	amino acid
GIY01_RS15345	COG2731	YhcH YjgK YiaL family protein
GIY01_RS15350	COG3250	beta-galactosidase activity
GIY01_RS15355	COG1609	Transcriptional regulator
GIY01_RS15360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GIY01_RS15370	COG1695	Transcriptional regulator
GIY01_RS15375	COG2375	cellular response to nickel ion
GIY01_RS15390	COG1461	Dihydroxyacetone kinase
GIY01_RS15395	COG2376	Dihydroxyacetone kinase
GIY01_RS15440	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GIY01_RS15450	COG0477	Major facilitator Superfamily
GIY01_RS15460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GIY01_RS15465	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GIY01_RS15480	COG3663	DNA glycosylase
GIY01_RS15490	COG0358	DNA primase activity
GIY01_RS15495	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GIY01_RS15505	COG0477	Major facilitator Superfamily
GIY01_RS15515	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GIY01_RS15530	COG4991	sh3 domain protein
GIY01_RS15535	COG3025	triphosphatase activity
GIY01_RS15555	COG2960	long-chain fatty acid transporting porin activity
GIY01_RS15565	COG3384	dioxygenase
GIY01_RS15570	COG0754	glutathionylspermidine amidase activity
GIY01_RS15585	COG0494	nUDIX hydrolase
GIY01_RS15590	COG3151	Protein conserved in bacteria
GIY01_RS15595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GIY01_RS15600	COG3150	esterase
GIY01_RS15605	COG0187	DNA topoisomerase II activity
GIY01_RS15610	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GIY01_RS15615	COG2249	NAD(P)H dehydrogenase (quinone) activity
GIY01_RS15620	COG0642	Histidine kinase
GIY01_RS15630	COG3111	PFAM Bacterial OB fold (BOF) protein
GIY01_RS15635	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GIY01_RS15645	COG0204	Acyl-transferase
GIY01_RS15655	COG1032	radical SAM domain protein
GIY01_RS15665	COG0656	L-ascorbic acid biosynthetic process
GIY01_RS15670	COG1979	alcohol dehydrogenase
GIY01_RS15675	COG2207	Transcriptional regulator
GIY01_RS15680	COG0586	Pfam SNARE associated Golgi protein
GIY01_RS15685	COG0626	cystathionine gamma-synthase activity
GIY01_RS15695	COG0848	biopolymer transport protein
GIY01_RS15705	COG0625	glutathione transferase activity
GIY01_RS15715	COG0754	glutathionylspermidine amidase activity
GIY01_RS15720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GIY01_RS15735	COG1802	Transcriptional regulator
GIY01_RS15745	COG2267	carboxylic ester hydrolase activity
GIY01_RS15750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GIY01_RS15755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GIY01_RS15760	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS15765	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GIY01_RS15780	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS15795	COG0583	DNA-binding transcription factor activity
GIY01_RS15800	COG1652	LysM domain
GIY01_RS15805	COG3753	Protein conserved in bacteria
GIY01_RS15810	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GIY01_RS15815	COG4977	sequence-specific DNA binding
GIY01_RS15815	COG1917	Cupin 2, conserved barrel domain protein
GIY01_RS15830	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GIY01_RS15840	COG4771	TonB-dependent receptor
GIY01_RS15850	COG2382	esterase
GIY01_RS15870	COG2186	Transcriptional regulator
GIY01_RS15895	COG2731	YhcH YjgK YiaL family protein
GIY01_RS15915	COG1811	Na channel or pump
GIY01_RS15920	COG1982	Orn Lys Arg decarboxylase major
GIY01_RS15925	COG2211	Major facilitator Superfamily
GIY01_RS15940	COG1194	a g-specific adenine glycosylase
GIY01_RS15950	COG3171	Protein conserved in bacteria
GIY01_RS15960	COG4214	carbohydrate transport
GIY01_RS15975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GIY01_RS15990	COG0762	integral membrane protein
GIY01_RS15995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GIY01_RS16000	COG2805	Type II/IV secretion system protein
GIY01_RS16005	COG2197	response regulator
GIY01_RS16020	COG0189	ligase activity
GIY01_RS16025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GIY01_RS16030	COG2356	endonuclease I
GIY01_RS16040	COG2814	Major facilitator Superfamily
GIY01_RS16085	COG2146	nitrite reductase [NAD(P)H] activity
GIY01_RS16100	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS16105	COG1414	Transcriptional regulator
GIY01_RS16135	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS16140	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
GIY01_RS16160	COG0501	Belongs to the peptidase M48B family
GIY01_RS16180	COG0191	fructose-bisphosphate aldolase activity
GIY01_RS16185	COG0668	transmembrane transport
GIY01_RS16190	COG1279	arginine transmembrane transporter activity
GIY01_RS16195	COG2968	Membrane
GIY01_RS16210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GIY01_RS16215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GIY01_RS16235	COG0006	proline dipeptidase activity
GIY01_RS16240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GIY01_RS16245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GIY01_RS16265	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS16270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GIY01_RS16290	COG2723	6-phospho-beta-galactosidase activity
GIY01_RS16295	COG1737	Transcriptional regulator
GIY01_RS16305	COG1272	protein, Hemolysin III
GIY01_RS16315	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GIY01_RS16325	COG0716	FMN binding
GIY01_RS16330	COG4974	Belongs to the 'phage' integrase family
GIY01_RS16340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GIY01_RS16360	COG1811	Na channel or pump
GIY01_RS16370	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GIY01_RS16385	COG3539	Fimbrial protein
GIY01_RS16395	COG3188	usher protein
GIY01_RS16400	COG3121	Chaperone
GIY01_RS16410	COG3539	Fimbrial protein
GIY01_RS16425	COG0124	histidyl-tRNA synthetase
GIY01_RS16430	COG0124	histidyl-tRNA synthetase
GIY01_RS16440	COG0531	amino acid
GIY01_RS16450	COG0753	catalase activity
GIY01_RS16455	COG1609	Transcriptional regulator
GIY01_RS16465	COG2271	Major facilitator Superfamily
GIY01_RS16495	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GIY01_RS16510	COG0531	amino acid
GIY01_RS16515	COG1982	Orn Lys Arg decarboxylase major
GIY01_RS16530	COG1538	Outer membrane efflux protein
GIY01_RS16535	COG1289	transmembrane transporter activity
GIY01_RS16550	COG3592	Divergent 4Fe-4S mono-cluster
GIY01_RS16555	COG2388	GCN5-related N-acetyl-transferase
GIY01_RS16565	COG3539	Fimbrial protein
GIY01_RS16570	COG3539	Fimbrial protein
GIY01_RS16575	COG3539	Fimbrial protein
GIY01_RS16580	COG3188	usher protein
GIY01_RS16585	COG3121	Chaperone
GIY01_RS16590	COG3539	Fimbrial protein
GIY01_RS16605	COG4974	Belongs to the 'phage' integrase family
GIY01_RS16610	COG0582	viral genome integration into host DNA
GIY01_RS16635	COG3539	Fimbrial protein
GIY01_RS16640	COG3121	Chaperone
GIY01_RS16645	COG3188	usher protein
GIY01_RS16660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GIY01_RS16670	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS16680	COG4638	Rieske (2fe-2S)
GIY01_RS16690	COG1960	acyl-CoA dehydrogenase activity
GIY01_RS16695	COG0154	amidase activity
GIY01_RS16705	COG1846	Transcriptional regulator
GIY01_RS16710	COG0697	spore germination
GIY01_RS16725	COG0640	Transcriptional regulator
GIY01_RS16740	COG0667	Aldo Keto reductase
GIY01_RS16745	COG0814	amino acid
GIY01_RS16755	COG0583	DNA-binding transcription factor activity
GIY01_RS16760	COG0183	Belongs to the thiolase family
GIY01_RS16765	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS16770	COG2814	Major facilitator Superfamily
GIY01_RS16810	COG0861	Integral membrane protein TerC family
GIY01_RS16820	COG0667	Aldo Keto reductase
GIY01_RS16835	COG1609	Transcriptional regulator
GIY01_RS16845	COG1609	Transcriptional regulator
GIY01_RS16855	COG0583	DNA-binding transcription factor activity
GIY01_RS16860	COG1794	racemase activity, acting on amino acids and derivatives
GIY01_RS16915	COG2165	general secretion pathway protein
GIY01_RS16920	COG4795	General secretion pathway protein
GIY01_RS16935	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GIY01_RS16940	COG1025	Belongs to the peptidase M16 family
GIY01_RS16945	COG1074	ATP-dependent DNA helicase activity
GIY01_RS16950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GIY01_RS16955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GIY01_RS16955	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GIY01_RS16960	COG0860	N-Acetylmuramoyl-L-alanine amidase
GIY01_RS16980	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GIY01_RS16985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GIY01_RS16990	COG2166	iron-sulfur cluster assembly
GIY01_RS16995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GIY01_RS17000	COG0583	DNA-binding transcription factor activity
GIY01_RS17005	COG2363	Small membrane protein
GIY01_RS17020	COG1760	l-serine dehydratase
GIY01_RS17025	COG0814	amino acid
GIY01_RS17030	COG1611	Belongs to the LOG family
GIY01_RS17045	COG3098	single-species biofilm formation
GIY01_RS17050	COG0564	pseudouridine synthase activity
GIY01_RS17055	COG0716	FMN binding
GIY01_RS17065	COG2271	Major facilitator Superfamily
GIY01_RS17070	COG4948	Mandelate Racemase Muconate Lactonizing
GIY01_RS17075	COG4948	Mandelate Racemase Muconate Lactonizing
GIY01_RS17080	COG1929	Belongs to the glycerate kinase type-1 family
GIY01_RS17090	COG3437	response regulator, receiver
GIY01_RS17090	COG2205	protein histidine kinase activity
GIY01_RS17090	COG3850	Histidine kinase
GIY01_RS17090	COG4999	Histidine kinase
GIY01_RS17100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GIY01_RS17105	COG3956	TIGRFAM MazG family protein
GIY01_RS17125	COG0602	queuosine metabolic process
GIY01_RS17130	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS17135	COG0720	synthase
GIY01_RS17155	COG2234	aminopeptidase activity
GIY01_RS17185	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GIY01_RS17215	COG4942	peptidase
GIY01_RS17215	COG1388	LysM domain
GIY01_RS17220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GIY01_RS17240	COG0163	prenyltransferase activity
GIY01_RS17245	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GIY01_RS17260	COG3121	Chaperone
GIY01_RS17295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIY01_RS17300	COG4558	Periplasmic binding protein
GIY01_RS17305	COG3720	iron ion transport
GIY01_RS17325	COG0679	Auxin Efflux Carrier
GIY01_RS17330	COG0583	DNA-binding transcription factor activity
GIY01_RS17340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GIY01_RS17345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GIY01_RS17350	COG1121	(ABC) transporter
GIY01_RS17365	COG0309	Hydrogenase expression formation protein (HypE)
GIY01_RS17370	COG0409	Hydrogenase expression formation protein
GIY01_RS17375	COG0298	carbon dioxide binding
GIY01_RS17380	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GIY01_RS17395	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIY01_RS17400	COG0651	ATP synthesis coupled electron transport
GIY01_RS17405	COG0650	Formate hydrogenlyase subunit 4
GIY01_RS17410	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GIY01_RS17410	COG3261	NADH dehydrogenase
GIY01_RS17415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GIY01_RS17420	COG3260	NADH ubiquinone oxidoreductase 20
GIY01_RS17430	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GIY01_RS17435	COG2723	6-phospho-beta-galactosidase activity
GIY01_RS17440	COG1263	PTS System
GIY01_RS17440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIY01_RS17445	COG1609	Transcriptional regulator
GIY01_RS17450	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIY01_RS17455	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GIY01_RS17460	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GIY01_RS17485	COG1349	DNA-binding transcription factor activity
GIY01_RS17490	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIY01_RS17495	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS17505	COG3732	PTS system glucitol sorbitol-specific
GIY01_RS17510	COG3730	PTS system glucitol sorbitol-specific
GIY01_RS17515	COG2951	lytic endotransglycosylase activity
GIY01_RS17530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GIY01_RS17535	COG0803	Belongs to the bacterial solute-binding protein 9 family
GIY01_RS17540	COG1546	Belongs to the CinA family
GIY01_RS17560	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GIY01_RS17590	COG2823	Periplasmic or secreted lipoprotein
GIY01_RS17595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GIY01_RS17600	COG1238	metal cluster binding
GIY01_RS17620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GIY01_RS17625	COG2814	Major facilitator Superfamily
GIY01_RS17630	COG1566	PFAM secretion protein HlyD family protein
GIY01_RS17635	COG1846	Transcriptional regulator
GIY01_RS17645	COG4176	ABC-type proline glycine betaine transport system permease component
GIY01_RS17655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GIY01_RS17660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GIY01_RS17670	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GIY01_RS17675	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GIY01_RS17685	COG4575	ribosome binding
GIY01_RS17715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GIY01_RS17720	COG0640	Transcriptional regulator
GIY01_RS17730	COG0583	DNA-binding transcription factor activity
GIY01_RS17735	COG0671	phosphoesterase, PA-phosphatase related
GIY01_RS17740	COG3284	Transcriptional regulator
GIY01_RS17750	COG4608	Belongs to the ABC transporter superfamily
GIY01_RS17755	COG0444	Belongs to the ABC transporter superfamily
GIY01_RS17760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GIY01_RS17765	COG0601	transmembrane transport
GIY01_RS17770	COG0747	negative chemotaxis
GIY01_RS17775	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GIY01_RS17805	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS17810	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GIY01_RS17815	COG0583	DNA-binding transcription factor activity
GIY01_RS17820	COG0477	Major facilitator Superfamily
GIY01_RS17825	COG4133	protoheme IX ABC transporter activity
GIY01_RS17830	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GIY01_RS17835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GIY01_RS17840	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GIY01_RS17850	COG1138	Cytochrome C-type biogenesis protein
GIY01_RS17855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GIY01_RS17860	COG3088	subunit of a heme lyase
GIY01_RS17860	COG4235	cytochrome complex assembly
GIY01_RS17865	COG3088	subunit of a heme lyase
GIY01_RS17865	COG4235	cytochrome complex assembly
GIY01_RS17870	COG3005	denitrification pathway
GIY01_RS17875	COG0243	molybdopterin cofactor binding
GIY01_RS17885	COG3813	Protein conserved in bacteria
GIY01_RS17895	COG2169	Transcriptional regulator
GIY01_RS17905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GIY01_RS17925	COG1074	ATP-dependent DNA helicase activity
GIY01_RS17940	COG0582	viral genome integration into host DNA
GIY01_RS17955	COG2867	negative regulation of translational initiation
GIY01_RS17970	COG0497	DNA recombination
GIY01_RS17985	COG4536	flavin adenine dinucleotide binding
GIY01_RS17990	COG4137	Cytochrome C assembly protein
GIY01_RS17995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GIY01_RS18030	COG2885	chlorophyll binding
GIY01_RS18035	COG2199	diguanylate cyclase activity
GIY01_RS18045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GIY01_RS18050	COG0287	Prephenate dehydrogenase
GIY01_RS18050	COG1605	Chorismate mutase
GIY01_RS18060	COG0077	Prephenate dehydratase
GIY01_RS18060	COG1605	Chorismate mutase
GIY01_RS18070	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GIY01_RS18075	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GIY01_RS18090	COG0542	response to heat
GIY01_RS18115	COG0477	Major facilitator Superfamily
GIY01_RS18120	COG5544	Lipoprotein
GIY01_RS18125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GIY01_RS18135	COG3148	PFAM DTW domain containing protein
GIY01_RS18140	COG3118	belongs to the thioredoxin family
GIY01_RS18145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GIY01_RS18160	COG0513	Belongs to the DEAD box helicase family
GIY01_RS18170	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GIY01_RS18185	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GIY01_RS18190	COG3026	antisigma factor binding
GIY01_RS18195	COG3086	response to oxidative stress
GIY01_RS18205	COG0681	Belongs to the peptidase S26 family
GIY01_RS18225	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GIY01_RS18235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIY01_RS18240	COG1737	Transcriptional regulator
GIY01_RS18250	COG0560	Phosphoserine phosphatase
GIY01_RS18265	COG0047	phosphoribosylformylglycinamidine synthase activity
GIY01_RS18265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GIY01_RS18270	COG2205	protein histidine kinase activity
GIY01_RS18275	COG3170	Tfp pilus assembly protein FimV
GIY01_RS18280	COG2204	response regulator
GIY01_RS18285	COG0347	Belongs to the P(II) protein family
GIY01_RS18290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GIY01_RS18290	COG1017	nitric oxide dioxygenase activity
GIY01_RS18300	COG2259	Doxx family
GIY01_RS18305	COG2814	Major facilitator Superfamily
GIY01_RS18310	COG3711	transcriptional antiterminator
GIY01_RS18315	COG3683	transport system, periplasmic component
GIY01_RS18320	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GIY01_RS18345	COG0822	iron-sulfur transferase activity
GIY01_RS18365	COG0633	Ferredoxin
GIY01_RS18370	COG2975	iron-sulfur cluster assembly
GIY01_RS18385	COG2897	thiosulfate sulfurtransferase activity
GIY01_RS18390	COG2373	Large extracellular alpha-helical protein
GIY01_RS18395	COG4953	penicillin-binding protein 1C
GIY01_RS18425	COG2976	Protein conserved in bacteria
GIY01_RS18440	COG1645	bacterial-type flagellum-dependent swarming motility
GIY01_RS18460	COG0516	GMP reductase activity
GIY01_RS18460	COG0517	IMP dehydrogenase activity
GIY01_RS18495	COG2200	EAL domain
GIY01_RS18500	COG0248	Ppx GppA phosphatase
GIY01_RS18515	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GIY01_RS18520	COG2211	Major facilitator Superfamily
GIY01_RS18530	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GIY01_RS18545	COG2723	6-phospho-beta-galactosidase activity
GIY01_RS18555	COG2233	PERMEase
GIY01_RS18570	COG1393	Belongs to the ArsC family
GIY01_RS18575	COG4783	chaperone-mediated protein folding
GIY01_RS18580	COG0628	permease
GIY01_RS18585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GIY01_RS18590	COG2716	regulation of RNA biosynthetic process
GIY01_RS18600	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GIY01_RS18610	COG2321	neutral zinc metallopeptidase
GIY01_RS18620	COG0400	carboxylic ester hydrolase activity
GIY01_RS18635	COG1393	Belongs to the ArsC family
GIY01_RS18645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GIY01_RS18650	COG0493	'glutamate synthase
GIY01_RS18650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GIY01_RS18660	COG5342	invasion associated locus B
GIY01_RS18665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GIY01_RS18685	COG0860	N-Acetylmuramoyl-L-alanine amidase
GIY01_RS18705	COG2837	iron assimilation
GIY01_RS18710	COG4150	thiosulfate binding
GIY01_RS18715	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GIY01_RS18720	COG4208	sulfate ABC transporter
GIY01_RS18725	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GIY01_RS18765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIY01_RS18790	COG3530	Putative quorum-sensing-regulated virulence factor
GIY01_RS18795	COG0385	Bile acid
GIY01_RS18800	COG0583	DNA-binding transcription factor activity
GIY01_RS18835	COG3415	Transposase
GIY01_RS18840	COG3415	Transposase
GIY01_RS18855	COG2200	EAL domain
GIY01_RS18855	COG2199	diguanylate cyclase activity
GIY01_RS18860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GIY01_RS18875	COG0667	Aldo Keto reductase
GIY01_RS18880	COG3961	Belongs to the TPP enzyme family
GIY01_RS18895	COG3279	Response regulator of the LytR AlgR family
GIY01_RS18900	COG3275	phosphorelay sensor kinase activity
GIY01_RS18905	COG0436	Aminotransferase
GIY01_RS18915	COG2807	transmembrane transport
GIY01_RS18920	COG0590	tRNA wobble adenosine to inosine editing
GIY01_RS18945	COG2116	formate transmembrane transporter activity
GIY01_RS18950	COG2853	Lipoprotein
GIY01_RS18960	COG3691	Protein conserved in bacteria
GIY01_RS18975	COG2062	phosphohistidine phosphatase, SixA
GIY01_RS19000	COG0730	response to heat
GIY01_RS19005	COG3101	peptidyl-lysine hydroxylation
GIY01_RS19020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GIY01_RS19025	COG2814	Major facilitator Superfamily
GIY01_RS19030	COG2188	Transcriptional regulator
GIY01_RS19040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GIY01_RS19045	COG1447	Phosphotransferase system cellobiose-specific component IIA
GIY01_RS19055	COG0561	phosphatase activity
GIY01_RS19070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GIY01_RS19080	COG0586	Pfam SNARE associated Golgi protein
GIY01_RS19090	COG0285	dihydrofolate synthase activity
GIY01_RS19095	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GIY01_RS19100	COG1286	toxin biosynthetic process
GIY01_RS19105	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GIY01_RS19110	COG0163	prenyltransferase activity
GIY01_RS19120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIY01_RS19135	COG4160	amino acid transport
GIY01_RS19140	COG4598	ABC transporter
GIY01_RS19160	COG1090	epimerase
GIY01_RS19165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GIY01_RS19170	COG0625	glutathione transferase activity
GIY01_RS19175	COG0625	glutathione transferase activity
GIY01_RS19180	COG0622	Phosphoesterase
GIY01_RS19210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GIY01_RS19215	COG0471	metal ion transport
GIY01_RS19215	COG0490	domain, Protein
GIY01_RS19225	COG0436	Aminotransferase
GIY01_RS19230	COG0583	DNA-binding transcription factor activity
GIY01_RS19275	COG0839	Belongs to the complex I subunit 6 family
GIY01_RS19285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GIY01_RS19290	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GIY01_RS19310	COG2153	protein acetylation
GIY01_RS19315	COG1169	isochorismate synthase
GIY01_RS19340	COG0318	PFAM AMP-dependent synthetase and ligase
GIY01_RS19365	COG0642	Histidine kinase
GIY01_RS19385	COG0247	lactate metabolic process
GIY01_RS19395	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GIY01_RS19400	COG2271	Major facilitator Superfamily
GIY01_RS19405	COG0584	glycerophosphoryl diester phosphodiesterase
GIY01_RS19410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GIY01_RS19445	COG0642	Histidine kinase
GIY01_RS19445	COG2198	Histidine kinase
GIY01_RS19465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GIY01_RS19465	COG2169	Transcriptional regulator
GIY01_RS19475	COG4615	Cyclic peptide transporter
GIY01_RS19480	COG2239	Acts as a magnesium transporter
GIY01_RS19485	COG0659	secondary active sulfate transmembrane transporter activity
GIY01_RS19500	COG0628	permease
GIY01_RS19525	COG1349	DNA-binding transcription factor activity
GIY01_RS19530	COG0494	nUDIX hydrolase
GIY01_RS19550	COG1061	Type III restriction enzyme res subunit
GIY01_RS19555	COG1187	pseudouridine synthase activity
GIY01_RS19560	COG2814	Major facilitator Superfamily
GIY01_RS19570	COG4172	Belongs to the ABC transporter superfamily
GIY01_RS19575	COG4239	(ABC) transporter, permease
GIY01_RS19580	COG4174	ABC transporter (Permease)
GIY01_RS19585	COG4166	transmembrane transport
GIY01_RS19590	COG2200	EAL domain
GIY01_RS19595	COG0791	NLP P60 protein
GIY01_RS19600	COG0671	phosphoesterase, PA-phosphatase related
GIY01_RS19605	COG0523	cobalamin synthesis protein
GIY01_RS19610	COG0246	Mannitol dehydrogenase
GIY01_RS19615	COG1312	Catalyzes the dehydration of D-mannonate
GIY01_RS19645	COG1105	Belongs to the carbohydrate kinase PfkB family
GIY01_RS19650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIY01_RS19650	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GIY01_RS19650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIY01_RS19660	COG2855	membrane
GIY01_RS19665	COG0583	DNA-binding transcription factor activity
GIY01_RS19680	COG0833	amino acid
GIY01_RS19685	COG4771	TonB-dependent receptor
GIY01_RS19715	COG2311	Membrane
GIY01_RS19730	COG1129	ABC transporter
GIY01_RS19740	COG2949	membrane
GIY01_RS19750	COG1346	cytolysis
GIY01_RS19760	COG0583	DNA-binding transcription factor activity
GIY01_RS19765	COG2271	Major facilitator Superfamily
GIY01_RS19780	COG0625	glutathione transferase activity
GIY01_RS19785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GIY01_RS19790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GIY01_RS19805	COG2723	6-phospho-beta-galactosidase activity
GIY01_RS19810	COG2226	methyltransferase
GIY01_RS19815	COG1538	Outer membrane efflux protein
GIY01_RS19820	COG0586	Pfam SNARE associated Golgi protein
GIY01_RS19830	COG1686	Belongs to the peptidase S11 family
GIY01_RS19840	COG0277	FAD linked oxidase domain protein
GIY01_RS19845	COG1472	Belongs to the glycosyl hydrolase 3 family
GIY01_RS19850	COG1732	Glycine betaine
GIY01_RS19855	COG1174	glycine betaine transport
GIY01_RS19860	COG1125	glycine betaine transport
GIY01_RS19865	COG1174	glycine betaine transport
GIY01_RS19875	COG0789	Transcriptional regulator
GIY01_RS19880	COG3275	phosphorelay sensor kinase activity
GIY01_RS19890	COG4807	Protein conserved in bacteria
GIY01_RS19895	COG4808	Protein conserved in bacteria
GIY01_RS19910	COG0489	protein tyrosine kinase activity
GIY01_RS19920	COG5455	response to cobalt ion
GIY01_RS19925	COG0583	DNA-binding transcription factor activity
GIY01_RS19930	COG2252	PERMEase
GIY01_RS19940	COG0583	DNA-binding transcription factor activity
GIY01_RS19950	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GIY01_RS19985	COG0351	phosphomethylpyrimidine kinase
GIY01_RS19990	COG1830	Aldolase
GIY01_RS20015	COG2390	Transcriptional regulator
GIY01_RS20025	COG1070	Carbohydrate kinase
GIY01_RS20040	COG0826	peptidase U32
GIY01_RS20045	COG0745	RESPONSE REGULATOR receiver
GIY01_RS20050	COG2205	protein histidine kinase activity
GIY01_RS20080	COG0443	Heat shock 70 kDa protein
GIY01_RS20085	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GIY01_RS20100	COG2982	Protein involved in outer membrane biogenesis
GIY01_RS20105	COG1253	flavin adenine dinucleotide binding
GIY01_RS20145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GIY01_RS20155	COG0463	Glycosyl transferase, family 2
GIY01_RS20170	COG2244	polysaccharide biosynthetic process
GIY01_RS20180	COG1215	transferase activity, transferring glycosyl groups
GIY01_RS20235	COG1088	dTDP-glucose 4,6-dehydratase activity
GIY01_RS20245	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GIY01_RS20270	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GIY01_RS20285	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GIY01_RS20300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GIY01_RS20305	COG0583	DNA-binding transcription factor activity
GIY01_RS20315	COG0531	amino acid
GIY01_RS20320	COG0640	Transcriptional regulator
GIY01_RS20325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GIY01_RS20330	COG2925	Exonuclease
GIY01_RS20340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GIY01_RS20340	COG2755	lipolytic protein G-D-S-L family
GIY01_RS20345	COG1686	Belongs to the peptidase S11 family
GIY01_RS20355	COG1289	transmembrane transporter activity
GIY01_RS20380	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GIY01_RS20390	COG0095	Lipoate-protein ligase
GIY01_RS20395	COG0477	Major facilitator Superfamily
GIY01_RS20405	COG5001	Diguanylate cyclase
GIY01_RS20405	COG3300	MHYT domain
GIY01_RS20410	COG3615	Tellurite resistance protein tehB
GIY01_RS20440	COG0534	Mate efflux family protein
GIY01_RS20450	COG1725	Transcriptional regulator
GIY01_RS20480	COG1181	Belongs to the D-alanine--D-alanine ligase family
GIY01_RS20485	COG0477	Major facilitator Superfamily
GIY01_RS20490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GIY01_RS20510	COG2977	Belongs to the P-Pant transferase superfamily
GIY01_RS20530	COG1376	ErfK ybiS ycfS ynhG family protein
GIY01_RS20555	COG2197	response regulator
GIY01_RS20570	COG1250	3-hydroxyacyl-CoA dehydrogenase
GIY01_RS20575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GIY01_RS20580	COG1960	acyl-CoA dehydrogenase activity
GIY01_RS20610	COG0154	amidase activity
GIY01_RS20635	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GIY01_RS20685	COG3504	Conjugal transfer protein
GIY01_RS20765	COG4771	TonB-dependent receptor
GIY01_RS20770	COG1021	2,3-dihydroxybenzoate-AMP ligase
GIY01_RS20790	COG3433	isochorismatase activity
GIY01_RS20790	COG2226	methyltransferase
GIY01_RS20790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GIY01_RS20805	COG1132	(ABC) transporter
GIY01_RS20810	COG2814	Major facilitator Superfamily
GIY01_RS20815	COG1169	isochorismate synthase
GIY01_RS20820	COG0582	viral genome integration into host DNA
GIY01_RS20835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIY01_RS20840	COG0735	belongs to the Fur family
GIY01_RS20850	COG0523	cobalamin synthesis protein
GIY01_RS20875	COG0523	cobalamin synthesis protein
GIY01_RS20905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GIY01_RS20910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GIY01_RS20915	COG1121	(ABC) transporter
GIY01_RS20920	COG0803	Belongs to the bacterial solute-binding protein 9 family
GIY01_RS20925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GIY01_RS20935	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GIY01_RS20965	COG0803	Belongs to the bacterial solute-binding protein 9 family
GIY01_RS20970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GIY01_RS20975	COG1121	(ABC) transporter
GIY01_RS20985	COG0582	viral genome integration into host DNA
GIY01_RS21010	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GIY01_RS21040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GIY01_RS21050	COG1418	mRNA catabolic process
GIY01_RS21055	COG0270	DNA (cytosine-5-)-methyltransferase activity
GIY01_RS21060	COG3727	T/G mismatch-specific endonuclease activity
GIY01_RS21065	COG0697	spore germination
GIY01_RS21070	COG2354	Protein conserved in bacteria
GIY01_RS21075	COG5475	Uncharacterized small protein (DUF2158)
GIY01_RS21105	COG0366	Alpha amylase catalytic
GIY01_RS21110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIY01_RS21120	COG0765	amino acid transport
GIY01_RS21125	COG1126	abc transporter atp-binding protein
GIY01_RS21130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GIY01_RS21135	COG2197	response regulator
GIY01_RS21145	COG2197	response regulator
GIY01_RS21175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GIY01_RS21180	COG3152	Membrane
GIY01_RS21185	COG3012	SEC-C Motif Domain Protein
GIY01_RS21185	COG3318	Belongs to the UPF0149 family
GIY01_RS21190	COG0814	amino acid
GIY01_RS21200	COG1528	Iron-storage protein
GIY01_RS21210	COG0477	Major facilitator Superfamily
GIY01_RS21220	COG1528	Iron-storage protein
GIY01_RS21225	COG1879	ABC-type sugar transport system periplasmic component
GIY01_RS21235	COG1172	Belongs to the binding-protein-dependent transport system permease family
GIY01_RS21265	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GIY01_RS21275	COG3102	Protein conserved in bacteria
GIY01_RS21295	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GIY01_RS21300	COG1801	Protein of unknown function DUF72
GIY01_RS21305	COG1335	isochorismatase
GIY01_RS21315	COG0494	nUDIX hydrolase
GIY01_RS21340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GIY01_RS21350	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GIY01_RS21355	COG0739	heme binding
GIY01_RS21360	COG1560	Kdo2-lipid A biosynthetic process
GIY01_RS21370	COG1737	Transcriptional regulator
GIY01_RS21375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GIY01_RS21380	COG0129	dihydroxy-acid dehydratase activity
GIY01_RS21385	COG0800	Aldolase
GIY01_RS21395	COG3141	response to X-ray
GIY01_RS21400	COG2979	Protein of unknown function (DUF533)
GIY01_RS21405	COG1770	oligopeptidase
GIY01_RS21410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIY01_RS21420	COG2372	response to copper ion
GIY01_RS21425	COG1276	copper resistance
GIY01_RS21455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIY01_RS21475	COG1396	sequence-specific DNA binding
GIY01_RS21500	COG1484	DNA-dependent DNA replication
GIY01_RS21545	COG3008	intermembrane lipid transfer
GIY01_RS21550	COG2995	paraquat-inducible protein a
GIY01_RS21555	COG1956	GAF domain-containing protein
GIY01_RS21575	COG2814	Major facilitator Superfamily
GIY01_RS21580	COG1414	Transcriptional regulator
GIY01_RS21610	COG0768	penicillin binding
GIY01_RS21615	COG2226	methyltransferase
GIY01_RS21630	COG3716	PTS system mannose fructose sorbose family IID component
GIY01_RS21635	COG3715	PTS system
GIY01_RS21640	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GIY01_RS21640	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIY01_RS21645	COG1253	flavin adenine dinucleotide binding
GIY01_RS21650	COG2200	EAL domain
GIY01_RS21655	COG1760	l-serine dehydratase
GIY01_RS21675	COG0251	oxidation-reduction process
GIY01_RS21680	COG1199	ATP-dependent helicase activity
GIY01_RS21690	COG3065	identical protein binding
GIY01_RS21700	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GIY01_RS21710	COG2894	cell division
GIY01_RS21725	COG0179	Fumarylacetoacetate (FAA) hydrolase
GIY01_RS21735	COG0582	viral genome integration into host DNA
GIY01_RS21775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIY01_RS21945	COG3728	DNA packaging
GIY01_RS21945	COG5484	DNA packaging
GIY01_RS22080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GIY01_RS22090	COG2135	peptidase activity
GIY01_RS22115	COG2719	SpoVR family
GIY01_RS22135	COG1619	proteins homologs of microcin C7 resistance protein MccF
GIY01_RS22145	COG4774	siderophore transport
GIY01_RS22160	COG2814	Major facilitator Superfamily
GIY01_RS22165	COG0583	DNA-binding transcription factor activity
GIY01_RS22180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GIY01_RS22185	COG1882	Formate acetyltransferase
GIY01_RS22190	COG1760	l-serine dehydratase
GIY01_RS22200	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GIY01_RS22210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIY01_RS22320	COG0582	viral genome integration into host DNA
GIY01_RS22330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIY01_RS22420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GIY01_RS22425	COG1403	HNH endonuclease
GIY01_RS22450	COG3772	lysozyme
GIY01_RS22530	COG4386	tail sheath protein
GIY01_RS22585	COG3274	enterobacterial common antigen metabolic process
GIY01_RS22620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GIY01_RS22645	COG3209	COG3209 Rhs family protein
GIY01_RS22710	COG3706	GGDEF domain
GIY01_RS22715	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GIY01_RS22720	COG1560	Kdo2-lipid A biosynthetic process
GIY01_RS22730	COG3182	Iron-regulated membrane protein
GIY01_RS22750	COG2203	Gaf domain
GIY01_RS22750	COG2199	diguanylate cyclase activity
GIY01_RS22755	COG3042	response to heat
GIY01_RS22760	COG3189	MarR family transcriptional regulator
GIY01_RS22765	COG0504	CTP synthase activity
GIY01_RS22770	COG2807	transmembrane transport
GIY01_RS22775	COG2207	Transcriptional regulator
GIY01_RS22785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GIY01_RS22790	COG2199	diguanylate cyclase activity
GIY01_RS22805	COG2766	serine protein kinase
GIY01_RS22810	COG3713	MltA-interacting MipA family protein
GIY01_RS22830	COG3139	Protein of unknown function (DUF1315)
GIY01_RS22840	COG1335	isochorismatase
GIY01_RS22845	COG0252	asparaginase activity
GIY01_RS22850	COG0616	signal peptide processing
GIY01_RS22855	COG0778	Nitroreductase
GIY01_RS22865	COG0709	Synthesizes selenophosphate from selenide and ATP
GIY01_RS22870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GIY01_RS22880	COG3321	synthase
GIY01_RS22880	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS22880	COG0604	alcohol dehydrogenase
GIY01_RS22890	COG0494	nUDIX hydrolase
GIY01_RS22895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GIY01_RS22900	COG2897	thiosulfate sulfurtransferase activity
GIY01_RS22905	COG4136	ATPase activity
GIY01_RS22910	COG4135	transport system, permease component
GIY01_RS22915	COG4134	Bacterial extracellular solute-binding protein
GIY01_RS22920	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GIY01_RS22925	COG0398	Pfam SNARE associated Golgi protein
GIY01_RS22930	COG0398	Pfam SNARE associated Golgi protein
GIY01_RS22935	COG0708	Exodeoxyribonuclease III
GIY01_RS22945	COG3138	arginine N-succinyltransferase
GIY01_RS22960	COG3678	ATP-independent chaperone mediated protein folding
GIY01_RS22965	COG0322	excinuclease ABC activity
GIY01_RS22975	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GIY01_RS22980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GIY01_RS22985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GIY01_RS22990	COG1447	Phosphotransferase system cellobiose-specific component IIA
GIY01_RS22995	COG2169	Transcriptional regulator
GIY01_RS22995	COG1917	Cupin 2, conserved barrel domain protein
GIY01_RS23000	COG1486	melibiose metabolic process
GIY01_RS23010	COG0753	catalase activity
GIY01_RS23020	COG1823	symporter activity
GIY01_RS23025	COG1988	membrane-bound metal-dependent
GIY01_RS23030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GIY01_RS23055	COG0727	PFAM Uncharacterised protein family (UPF0153)
GIY01_RS23060	COG3047	cAMP biosynthetic process
GIY01_RS23065	COG0583	DNA-binding transcription factor activity
GIY01_RS23080	COG1566	PFAM secretion protein HlyD family protein
GIY01_RS23105	COG0134	indole-3-glycerol-phosphate synthase activity
GIY01_RS23105	COG0135	phosphoribosylanthranilate isomerase activity
GIY01_RS23110	COG0512	Glutamine amidotransferase of anthranilate synthase
GIY01_RS23110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GIY01_RS23115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GIY01_RS23125	COG0009	L-threonylcarbamoyladenylate synthase
GIY01_RS23135	COG5001	Diguanylate cyclase
GIY01_RS23135	COG1716	ATPase activity
GIY01_RS23145	COG2211	Major facilitator Superfamily
GIY01_RS23150	COG1472	Belongs to the glycosyl hydrolase 3 family
GIY01_RS23155	COG2207	Transcriptional regulator
GIY01_RS23160	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GIY01_RS23165	COG1028	Short-chain dehydrogenase reductase Sdr
GIY01_RS23170	COG0616	signal peptide processing
GIY01_RS23195	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GIY01_RS23205	COG0671	phosphoesterase, PA-phosphatase related
GIY01_RS23210	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GIY01_RS23215	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GIY01_RS23225	COG0023	Translation Initiation Factor
GIY01_RS23235	COG1349	DNA-binding transcription factor activity
GIY01_RS23250	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GIY01_RS23250	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GIY01_RS23255	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GIY01_RS23265	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GIY01_RS23270	COG4172	Belongs to the ABC transporter superfamily
GIY01_RS23280	COG4171	peptide transport system, permease
GIY01_RS23305	COG1473	amidohydrolase
GIY01_RS23315	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GIY01_RS23320	COG1842	Phage shock protein A
GIY01_RS23330	COG1983	PspC domain protein
GIY01_RS23340	COG3106	COG3106 Predicted ATPase
GIY01_RS23355	COG3180	Ammonia monooxygenase
GIY01_RS23360	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GIY01_RS23365	COG4948	Mandelate Racemase Muconate Lactonizing
GIY01_RS23370	COG2866	Carboxypeptidase
GIY01_RS23375	COG4166	transmembrane transport
GIY01_RS23385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GIY01_RS23400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GIY01_RS23410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GIY01_RS23420	COG0656	L-ascorbic acid biosynthetic process
GIY01_RS23470	COG0693	protein deglycase activity
GIY01_RS23480	COG0673	inositol 2-dehydrogenase activity
GIY01_RS23485	COG1349	DNA-binding transcription factor activity
GIY01_RS23490	COG4172	Belongs to the ABC transporter superfamily
GIY01_RS23515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GIY01_RS23520	COG1940	carbohydrate kinase activity
GIY01_RS23525	COG0456	acetyltransferase
GIY01_RS23535	COG0513	Belongs to the DEAD box helicase family
GIY01_RS23545	COG0589	response to stress
GIY01_RS23550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GIY01_RS23555	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GIY01_RS23555	COG0674	pyruvate-flavodoxin oxidoreductase activity
GIY01_RS23555	COG1013	pyruvate-flavodoxin oxidoreductase activity
GIY01_RS23555	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GIY01_RS23560	COG3042	response to heat
GIY01_RS23565	COG3187	Heat shock protein
GIY01_RS23570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GIY01_RS23575	COG0586	Pfam SNARE associated Golgi protein
GIY01_RS23580	COG2911	Protein conserved in bacteria
GIY01_RS23590	COG3784	Protein of unknown function (DUF1318)
GIY01_RS23595	COG2207	Transcriptional regulator
GIY01_RS23600	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS23615	COG2030	dehydratase
GIY01_RS23615	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS23620	COG3396	Phenylacetate-CoA oxygenase
GIY01_RS23625	COG3460	Phenylacetate-CoA oxygenase
GIY01_RS23630	COG3396	Phenylacetate-CoA oxygenase
GIY01_RS23635	COG2151	metal-sulfur cluster biosynthetic enzyme
GIY01_RS23640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GIY01_RS23645	COG1024	Enoyl-CoA hydratase
GIY01_RS23650	COG1024	Enoyl-CoA hydratase
GIY01_RS23655	COG1250	3-hydroxyacyl-CoA dehydrogenase
GIY01_RS23660	COG2050	protein possibly involved in aromatic compounds catabolism
GIY01_RS23665	COG0183	Belongs to the thiolase family
GIY01_RS23670	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GIY01_RS23675	COG3327	negative regulation of DNA-templated transcription, initiation
GIY01_RS23680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GIY01_RS23695	COG1643	Atp-dependent helicase
GIY01_RS23700	COG4122	O-methyltransferase activity
GIY01_RS23725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GIY01_RS23730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GIY01_RS23735	COG3138	arginine N-succinyltransferase
GIY01_RS23740	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS23745	COG3724	N-succinylarginine dihydrolase activity
GIY01_RS23750	COG2988	succinylglutamate desuccinylase activity
GIY01_RS23755	COG1113	amino acid transport
GIY01_RS23760	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GIY01_RS23765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GIY01_RS23800	COG3038	cytochrome b561
GIY01_RS23840	COG0583	DNA-binding transcription factor activity
GIY01_RS23845	COG3485	protocatechuate 3,4-dioxygenase
GIY01_RS23850	COG3485	protocatechuate 3,4-dioxygenase
GIY01_RS23855	COG5383	Protein conserved in bacteria
GIY01_RS23860	COG2272	Belongs to the type-B carboxylesterase lipase family
GIY01_RS23865	COG0583	DNA-binding transcription factor activity
GIY01_RS23870	COG1335	isochorismatase
GIY01_RS23875	COG1823	symporter activity
GIY01_RS23880	COG0436	Aminotransferase
GIY01_RS23905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GIY01_RS23910	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GIY01_RS23915	COG1275	C4-dicarboxylate transporter malic acid transport protein
GIY01_RS23920	COG0500	methyltransferase
GIY01_RS23925	COG2195	Cleaves the N-terminal amino acid of tripeptides
GIY01_RS23930	COG0747	negative chemotaxis
GIY01_RS23940	COG0697	spore germination
GIY01_RS23945	COG3708	Transcriptional regulator
GIY01_RS23945	COG2207	Transcriptional regulator
GIY01_RS23950	COG3135	benzoate transporter
GIY01_RS23955	COG1396	sequence-specific DNA binding
GIY01_RS23960	COG0826	peptidase U32
GIY01_RS23975	COG1294	oxidase, subunit
GIY01_RS23980	COG1271	oxidase subunit
GIY01_RS23985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GIY01_RS23990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GIY01_RS23995	COG3842	ATPase activity
GIY01_RS24000	COG1176	ABC-type spermidine putrescine transport system, permease component I
GIY01_RS24005	COG1177	transmembrane transport
GIY01_RS24010	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS24035	COG2267	carboxylic ester hydrolase activity
GIY01_RS24040	COG1012	belongs to the aldehyde dehydrogenase family
GIY01_RS24045	COG0747	negative chemotaxis
GIY01_RS24055	COG3238	Protein conserved in bacteria
GIY01_RS24060	COG1247	-acetyltransferase
GIY01_RS24070	COG2130	NADP-dependent
GIY01_RS24075	COG3691	Protein conserved in bacteria
GIY01_RS24080	COG4772	TonB-dependent receptor
GIY01_RS24110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GIY01_RS24115	COG1473	amidohydrolase
GIY01_RS24120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GIY01_RS24125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIY01_RS24140	COG1126	abc transporter atp-binding protein
GIY01_RS24145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GIY01_RS24155	COG0625	glutathione transferase activity
GIY01_RS24180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GIY01_RS24185	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GIY01_RS24190	COG2181	nitrate reductase activity
GIY01_RS24195	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GIY01_RS24200	COG1140	nitrate reductase beta subunit
GIY01_RS24205	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GIY01_RS24225	COG1414	Transcriptional regulator
GIY01_RS24230	COG4948	Mandelate Racemase Muconate Lactonizing
GIY01_RS24235	COG4829	muconolactone delta-isomerase
GIY01_RS24240	COG3485	protocatechuate 3,4-dioxygenase
GIY01_RS24250	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GIY01_RS24265	COG0697	spore germination
GIY01_RS24275	COG0437	4 iron, 4 sulfur cluster binding
GIY01_RS24280	COG2864	formate dehydrogenase
GIY01_RS24340	COG2814	Major facilitator Superfamily
GIY01_RS24350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GIY01_RS24360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GIY01_RS24370	COG0747	negative chemotaxis
GIY01_RS24375	COG1064	alcohol dehydrogenase
GIY01_RS24385	COG0488	(ABC) transporter
GIY01_RS24405	COG1609	Transcriptional regulator
GIY01_RS24430	COG1764	response to oxidative stress
GIY01_RS24445	COG2837	iron assimilation
GIY01_RS24450	COG3781	membrane
GIY01_RS24460	COG1294	oxidase, subunit
GIY01_RS24465	COG1271	oxidase subunit
GIY01_RS24470	COG0243	molybdopterin cofactor binding
GIY01_RS24475	COG0583	DNA-binding transcription factor activity
GIY01_RS24480	COG0583	DNA-binding transcription factor activity
GIY01_RS24490	COG2271	Major facilitator Superfamily
GIY01_RS24515	COG1309	transcriptional regulator
GIY01_RS24520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GIY01_RS24530	COG0583	DNA-binding transcription factor activity
GIY01_RS24600	COG2205	protein histidine kinase activity
GIY01_RS24610	COG0076	glutamate decarboxylase activity
GIY01_RS24615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GIY01_RS24620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GIY01_RS24625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GIY01_RS24630	COG1116	anion transmembrane transporter activity
GIY01_RS24635	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GIY01_RS24670	COG0583	DNA-binding transcription factor activity
GIY01_RS24675	COG2070	2-Nitropropane dioxygenase
GIY01_RS24680	COG1649	PFAM Uncharacterised BCR, COG1649
GIY01_RS24885	COG0668	transmembrane transport
GIY01_RS24890	COG0454	-acetyltransferase
GIY01_RS24920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GIY01_RS24925	COG2233	PERMEase
GIY01_RS24935	COG2351	hydroxyisourate hydrolase activity
GIY01_RS24945	COG1953	Uracil, thiamine, allantoin
GIY01_RS24995	COG0765	amino acid transport
GIY01_RS25000	COG0765	amino acid transport
GIY01_RS25010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GIY01_RS25020	COG2814	Major facilitator Superfamily
GIY01_RS25025	COG0583	DNA-binding transcription factor activity
GIY01_RS25095	COG0667	Aldo Keto reductase
GIY01_RS25100	COG2249	NAD(P)H dehydrogenase (quinone) activity
GIY01_RS25110	COG0656	L-ascorbic acid biosynthetic process
GIY01_RS25135	COG0667	Aldo Keto reductase
GIY01_RS25140	COG0667	Aldo Keto reductase
GIY01_RS25145	COG0667	Aldo Keto reductase
GIY01_RS25155	COG1609	Transcriptional regulator
GIY01_RS25160	COG1940	carbohydrate kinase activity
GIY01_RS25165	COG1447	Phosphotransferase system cellobiose-specific component IIA
GIY01_RS25170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GIY01_RS25175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GIY01_RS25180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GIY01_RS25185	COG4580	involved in the transport of maltose and maltodextrins