locus-tag	class	description
HV042_RS00010	COG0592	DNA-directed DNA polymerase activity
HV042_RS00025	COG0583	DNA-binding transcription factor activity
HV042_RS00035	COG0561	phosphatase activity
HV042_RS00040	COG2186	Transcriptional regulator
HV042_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
HV042_RS00050	COG0800	Aldolase
HV042_RS00065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HV042_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
HV042_RS00075	COG5645	(Lipo)protein
HV042_RS00100	COG2188	Transcriptional regulator
HV042_RS00115	COG2149	membrane
HV042_RS00125	COG0641	radical SAM
HV042_RS00135	COG2610	gluconate transmembrane transporter activity
HV042_RS00140	COG0583	DNA-binding transcription factor activity
HV042_RS00150	COG2814	Major facilitator Superfamily
HV042_RS00175	COG0028	Belongs to the TPP enzyme family
HV042_RS00180	COG0440	acetolactate synthase activity
HV042_RS00190	COG2197	response regulator
HV042_RS00200	COG2271	Major facilitator Superfamily
HV042_RS00230	COG4580	involved in the transport of maltose and maltodextrins
HV042_RS00235	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV042_RS00240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV042_RS00240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV042_RS00250	COG1609	Transcriptional regulator
HV042_RS00260	COG5464	transposase or invertase
HV042_RS00270	COG0697	spore germination
HV042_RS00275	COG1263	PTS System
HV042_RS00275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV042_RS00285	COG2814	Major facilitator Superfamily
HV042_RS00295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV042_RS00300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV042_RS00310	COG1309	transcriptional regulator
HV042_RS00320	COG0583	DNA-binding transcription factor activity
HV042_RS00335	COG1464	Belongs to the NlpA lipoprotein family
HV042_RS00350	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HV042_RS00375	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HV042_RS00450	COG0582	viral genome integration into host DNA
HV042_RS00460	COG2211	Major facilitator Superfamily
HV042_RS00465	COG1501	Belongs to the glycosyl hydrolase 31 family
HV042_RS00470	COG3711	transcriptional antiterminator
HV042_RS00475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV042_RS00475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV042_RS00475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS00480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV042_RS00485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV042_RS00485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV042_RS00500	COG1940	carbohydrate kinase activity
HV042_RS00515	COG1486	melibiose metabolic process
HV042_RS00520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV042_RS00520	COG1263	PTS System
HV042_RS00525	COG2982	Protein involved in outer membrane biogenesis
HV042_RS00530	COG2233	PERMEase
HV042_RS00535	COG0786	glutamate:sodium symporter activity
HV042_RS00550	COG3074	FtsZ-dependent cytokinesis
HV042_RS00565	COG2211	Major facilitator Superfamily
HV042_RS00570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV042_RS00580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV042_RS00600	COG3152	Membrane
HV042_RS00610	COG1494	fructose-1,6-bisphosphatase
HV042_RS00615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HV042_RS00620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV042_RS00625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV042_RS00645	COG2860	membrane
HV042_RS00655	COG1561	YicC-like family, N-terminal region
HV042_RS00665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HV042_RS00680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HV042_RS00690	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HV042_RS00695	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HV042_RS00700	COG4245	von Willebrand factor, type A
HV042_RS00735	COG1519	Transferase
HV042_RS00740	COG1216	Glycosyl transferase, family 2
HV042_RS00745	COG0438	transferase activity, transferring glycosyl groups
HV042_RS00755	COG0859	PFAM glycosyl transferase family 9
HV042_RS00780	COG0859	PFAM glycosyl transferase family 9
HV042_RS00785	COG0859	PFAM glycosyl transferase family 9
HV042_RS00810	COG2861	carbohydrate metabolic process
HV042_RS00815	COG4942	peptidase
HV042_RS00825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV042_RS00830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV042_RS00850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HV042_RS00860	COG2186	Transcriptional regulator
HV042_RS00880	COG3722	fumarate hydratase activity
HV042_RS00900	COG1566	PFAM secretion protein HlyD family protein
HV042_RS00905	COG0625	glutathione transferase activity
HV042_RS00915	COG3276	selenocysteine insertion sequence binding
HV042_RS00925	COG2211	Major facilitator Superfamily
HV042_RS00930	COG1917	Cupin 2, conserved barrel domain protein
HV042_RS00930	COG4977	sequence-specific DNA binding
HV042_RS00935	COG0235	Class ii aldolase
HV042_RS00940	COG3623	hexulose-6-phosphate isomerase
HV042_RS00945	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HV042_RS00950	COG1070	Carbohydrate kinase
HV042_RS00965	COG2731	YhcH YjgK YiaL family protein
HV042_RS00970	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV042_RS00975	COG1414	Transcriptional regulator
HV042_RS00980	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV042_RS00985	COG3977	Valine--pyruvate aminotransferase
HV042_RS00990	COG0366	Alpha amylase catalytic
HV042_RS00995	COG2992	FlgJ-related protein
HV042_RS01000	COG1609	Transcriptional regulator
HV042_RS01000	COG2207	Transcriptional regulator
HV042_RS01005	COG4214	carbohydrate transport
HV042_RS01015	COG4213	ABC transporter substrate-binding protein
HV042_RS01020	COG2115	Belongs to the xylose isomerase family
HV042_RS01025	COG1070	Carbohydrate kinase
HV042_RS01030	COG4682	membrane
HV042_RS01035	COG3274	enterobacterial common antigen metabolic process
HV042_RS01065	COG1278	Cold shock
HV042_RS01070	COG2944	sequence-specific DNA binding
HV042_RS01075	COG2814	Major facilitator Superfamily
HV042_RS01095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV042_RS01105	COG1609	Transcriptional regulator
HV042_RS01110	COG2885	chlorophyll binding
HV042_RS01115	COG0243	molybdopterin cofactor binding
HV042_RS01120	COG0456	acetyltransferase
HV042_RS01125	COG2818	Glycosylase
HV042_RS01130	COG5571	outer membrane autotransporter
HV042_RS01135	COG2223	nitrite transmembrane transporter activity
HV042_RS01150	COG0747	negative chemotaxis
HV042_RS01155	COG0601	transmembrane transport
HV042_RS01160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV042_RS01165	COG0444	Belongs to the ABC transporter superfamily
HV042_RS01170	COG4608	Belongs to the ABC transporter superfamily
HV042_RS01180	COG0489	protein tyrosine kinase activity
HV042_RS01195	COG0457	Tetratricopeptide repeat
HV042_RS01215	COG2194	sulfuric ester hydrolase activity
HV042_RS01245	COG1215	transferase activity, transferring glycosyl groups
HV042_RS01250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HV042_RS01255	COG3118	belongs to the thioredoxin family
HV042_RS01255	COG0457	Tetratricopeptide repeat
HV042_RS01260	COG2200	EAL domain
HV042_RS01260	COG2199	diguanylate cyclase activity
HV042_RS01270	COG0612	Peptidase, M16
HV042_RS01280	COG2982	Protein involved in outer membrane biogenesis
HV042_RS01285	COG0477	Major facilitator Superfamily
HV042_RS01290	COG1295	ribonuclease BN
HV042_RS01295	COG0583	DNA-binding transcription factor activity
HV042_RS01300	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS01305	COG2197	response regulator
HV042_RS01325	COG1454	alcohol dehydrogenase
HV042_RS01335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV042_RS01340	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HV042_RS01345	COG0671	phosphoesterase, PA-phosphatase related
HV042_RS01350	COG2205	protein histidine kinase activity
HV042_RS01355	COG0745	RESPONSE REGULATOR receiver
HV042_RS01360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV042_RS01365	COG2183	response to ionizing radiation
HV042_RS01370	COG1918	ferrous iron import across plasma membrane
HV042_RS01395	COG1040	competence protein
HV042_RS01405	COG2610	gluconate transmembrane transporter activity
HV042_RS01430	COG1959	2 iron, 2 sulfur cluster binding
HV042_RS01440	COG0589	response to stress
HV042_RS01450	COG0306	phosphate transporter
HV042_RS01455	COG2081	HI0933 family
HV042_RS01465	COG3039	Transposase
HV042_RS01470	COG3964	amidohydrolase
HV042_RS01475	COG0471	metal ion transport
HV042_RS01480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HV042_RS01485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV042_RS01495	COG2239	Acts as a magnesium transporter
HV042_RS01510	COG0444	Belongs to the ABC transporter superfamily
HV042_RS01515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV042_RS01520	COG0601	transmembrane transport
HV042_RS01525	COG0747	negative chemotaxis
HV042_RS01535	COG3479	Phenolic acid decarboxylase
HV042_RS01575	COG0628	permease
HV042_RS01580	COG0477	Major facilitator Superfamily
HV042_RS01590	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HV042_RS01605	COG3714	YhhN family
HV042_RS01615	COG3776	membrane
HV042_RS01620	COG0742	ribosomal rna small subunit methyltransferase
HV042_RS01625	COG0552	protein localization to endoplasmic reticulum
HV042_RS01630	COG2884	Cell division ATP-binding protein ftsE
HV042_RS01635	COG2177	Part of the ABC transporter FtsEX involved in
HV042_RS01650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV042_RS01665	COG0683	leucine binding
HV042_RS01700	COG2721	sulfolactate sulfo-lyase activity
HV042_RS01705	COG2271	Major facilitator Superfamily
HV042_RS01710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV042_RS01715	COG1414	Transcriptional regulator
HV042_RS01740	COG0584	glycerophosphoryl diester phosphodiesterase
HV042_RS01750	COG0405	Gamma-glutamyltransferase
HV042_RS01755	COG1247	-acetyltransferase
HV042_RS01765	COG0673	inositol 2-dehydrogenase activity
HV042_RS01770	COG1741	Belongs to the pirin family
HV042_RS01775	COG1609	Transcriptional regulator
HV042_RS01780	COG3265	gluconokinase activity
HV042_RS01785	COG2610	gluconate transmembrane transporter activity
HV042_RS01800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV042_RS01825	COG0058	SHG alpha-glucan phosphorylase activity
HV042_RS01830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV042_RS01845	COG1349	DNA-binding transcription factor activity
HV042_RS01855	COG0058	SHG alpha-glucan phosphorylase activity
HV042_RS01860	COG1640	4-alpha-glucanotransferase
HV042_RS01875	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HV042_RS01880	COG1011	Hydrolase
HV042_RS01890	COG0494	nUDIX hydrolase
HV042_RS01895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HV042_RS01905	COG3166	PFAM Fimbrial assembly family protein
HV042_RS01920	COG4796	Type ii and iii secretion system protein
HV042_RS01935	COG3266	domain, Protein
HV042_RS01940	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV042_RS01945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV042_RS01970	COG2146	nitrite reductase [NAD(P)H] activity
HV042_RS01975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV042_RS01980	COG0402	S-adenosylhomocysteine deaminase activity
HV042_RS01985	COG0738	Major facilitator superfamily
HV042_RS02010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HV042_RS02015	COG1289	transmembrane transporter activity
HV042_RS02025	COG1765	OsmC-like protein
HV042_RS02030	COG3954	Phosphoribulokinase
HV042_RS02040	COG0429	hydrolase of the alpha beta-hydrolase fold
HV042_RS02050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HV042_RS02060	COG0488	(ABC) transporter
HV042_RS02075	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HV042_RS02080	COG1047	Peptidyl-prolyl cis-trans
HV042_RS02090	COG0545	Peptidyl-prolyl cis-trans isomerase
HV042_RS02095	COG2964	Protein conserved in bacteria
HV042_RS02150	COG0051	transcription antitermination factor activity, RNA binding
HV042_RS02160	COG0088	Forms part of the polypeptide exit tunnel
HV042_RS02175	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HV042_RS02190	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HV042_RS02240	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HV042_RS02255	COG0201	protein transport
HV042_RS02270	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HV042_RS02280	COG0202	RNA polymerase activity
HV042_RS02285	COG0203	ribosomal protein L17
HV042_RS02295	COG0789	Transcriptional regulator
HV042_RS02300	COG3036	rescue of stalled ribosome
HV042_RS02330	COG0758	DNA mediated transformation
HV042_RS02340	COG0551	DNA topoisomerase type I activity
HV042_RS02360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV042_RS02400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV042_RS02405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV042_RS02410	COG1309	transcriptional regulator
HV042_RS02435	COG4145	pantothenate transmembrane transporter activity
HV042_RS02440	COG3924	membrane
HV042_RS02445	COG0439	Biotin carboxylase
HV042_RS02450	COG0511	ligase activity, forming carbon-carbon bonds
HV042_RS02465	COG0604	alcohol dehydrogenase
HV042_RS02470	COG2199	diguanylate cyclase activity
HV042_RS02470	COG2200	EAL domain
HV042_RS02475	COG1077	Cell shape determining protein MreB Mrl
HV042_RS02480	COG1792	Involved in formation and maintenance of cell shape
HV042_RS02485	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HV042_RS02495	COG1530	ribonuclease E activity
HV042_RS02500	COG3164	Protein of unknown function
HV042_RS02505	COG0312	modulator of DNA gyrase
HV042_RS02510	COG1349	DNA-binding transcription factor activity
HV042_RS02515	COG0583	DNA-binding transcription factor activity
HV042_RS02530	COG1289	transmembrane transporter activity
HV042_RS02535	COG2732	(Barnase) inhibitor
HV042_RS02560	COG2188	Transcriptional regulator
HV042_RS02570	COG0471	metal ion transport
HV042_RS02575	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV042_RS02580	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV042_RS02590	COG0511	ligase activity, forming carbon-carbon bonds
HV042_RS02590	COG5016	pyruvate
HV042_RS02605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV042_RS02610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV042_RS02615	COG3105	Protein conserved in bacteria
HV042_RS02620	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HV042_RS02635	COG0625	glutathione transferase activity
HV042_RS02640	COG2969	positive regulation of protein catabolic process
HV042_RS02650	COG0493	'glutamate synthase
HV042_RS02655	COG0070	glutamate synthase
HV042_RS02655	COG0069	glutamate synthase activity
HV042_RS02655	COG0067	glutamate synthase
HV042_RS02660	COG1242	4 iron, 4 sulfur cluster binding
HV042_RS02665	COG0784	Response regulator, receiver
HV042_RS02665	COG5002	protein histidine kinase activity
HV042_RS02665	COG2198	Histidine kinase
HV042_RS02670	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HV042_RS02675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HV042_RS02680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS02685	COG1660	Displays ATPase and GTPase activities
HV042_RS02690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS02695	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV042_RS02700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HV042_RS02705	COG1137	ATPase activity
HV042_RS02710	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HV042_RS02715	COG3117	lipopolysaccharide transmembrane transporter activity
HV042_RS02720	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HV042_RS02730	COG0530	calcium, potassium:sodium antiporter activity
HV042_RS02735	COG1127	ABC transporter
HV042_RS02740	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV042_RS02745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV042_RS02750	COG2854	intermembrane phospholipid transfer
HV042_RS02755	COG3113	response to antibiotic
HV042_RS02760	COG5007	Belongs to the BolA IbaG family
HV042_RS02770	COG3423	Transcriptional regulator
HV042_RS02775	COG0142	geranyltranstransferase activity
HV042_RS02790	COG0697	spore germination
HV042_RS02800	COG2027	D-alanyl-D-alanine carboxypeptidase
HV042_RS02810	COG1534	Rna-binding protein
HV042_RS02820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HV042_RS02825	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HV042_RS02835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HV042_RS02860	COG0195	Participates in both transcription termination and antitermination
HV042_RS02865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HV042_RS02900	COG0513	Belongs to the DEAD box helicase family
HV042_RS02905	COG0814	amino acid
HV042_RS02930	COG0511	ligase activity, forming carbon-carbon bonds
HV042_RS02975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV042_RS02980	COG0826	peptidase U32
HV042_RS02985	COG0826	peptidase U32
HV042_RS02990	COG3154	lipid carrier protein
HV042_RS02995	COG3153	acetyltransferase
HV042_RS03000	COG2827	Endonuclease containing a URI domain
HV042_RS03010	COG0693	protein deglycase activity
HV042_RS03015	COG0702	epimerase
HV042_RS03020	COG0701	Predicted permease
HV042_RS03025	COG2823	Periplasmic or secreted lipoprotein
HV042_RS03045	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HV042_RS03060	COG1063	alcohol dehydrogenase
HV042_RS03065	COG3775	system Galactitol-specific IIC component
HV042_RS03070	COG3414	Phosphotransferase system galactitol-specific IIB component
HV042_RS03075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS03080	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
HV042_RS03085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS03085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS03090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS03090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV042_RS03090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV042_RS03100	COG0191	fructose-bisphosphate aldolase activity
HV042_RS03105	COG1349	DNA-binding transcription factor activity
HV042_RS03110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV042_RS03115	COG2721	sulfolactate sulfo-lyase activity
HV042_RS03120	COG2271	Major facilitator Superfamily
HV042_RS03130	COG2084	Dehydrogenase
HV042_RS03135	COG1929	Belongs to the glycerate kinase type-1 family
HV042_RS03165	COG1741	Belongs to the pirin family
HV042_RS03170	COG0583	DNA-binding transcription factor activity
HV042_RS03175	COG3152	Membrane
HV042_RS03180	COG0435	Glutathione S-transferase
HV042_RS03185	COG2259	Doxx family
HV042_RS03195	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HV042_RS03200	COG4575	ribosome binding
HV042_RS03205	COG1422	Protein of unknown function (DUF1090)
HV042_RS03215	COG0586	Pfam SNARE associated Golgi protein
HV042_RS03220	COG2186	Transcriptional regulator
HV042_RS03225	COG2271	Major facilitator Superfamily
HV042_RS03235	COG2721	sulfolactate sulfo-lyase activity
HV042_RS03255	COG0673	inositol 2-dehydrogenase activity
HV042_RS03260	COG1451	nucleotide metabolic process
HV042_RS03265	COG3507	Belongs to the glycosyl hydrolase 43 family
HV042_RS03275	COG2211	Major facilitator Superfamily
HV042_RS03285	COG1902	pentaerythritol trinitrate reductase activity
HV042_RS03285	COG0446	pyridine nucleotide-disulphide oxidoreductase
HV042_RS03305	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS03335	COG1695	Transcriptional regulator
HV042_RS03340	COG2375	cellular response to nickel ion
HV042_RS03355	COG1461	Dihydroxyacetone kinase
HV042_RS03360	COG2376	Dihydroxyacetone kinase
HV042_RS03380	COG0582	viral genome integration into host DNA
HV042_RS03460	COG1802	Transcriptional regulator
HV042_RS03460	COG4626	Terminase
HV042_RS03495	COG0358	DNA primase activity
HV042_RS03500	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HV042_RS03555	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV042_RS03570	COG4991	sh3 domain protein
HV042_RS03575	COG3025	triphosphatase activity
HV042_RS03600	COG2960	long-chain fatty acid transporting porin activity
HV042_RS03610	COG3539	Fimbrial protein
HV042_RS03615	COG3121	Chaperone
HV042_RS03620	COG3188	usher protein
HV042_RS03625	COG3539	Fimbrial protein
HV042_RS03650	COG2842	Transposition protein
HV042_RS03680	COG4382	Mu-like prophage protein Gp16
HV042_RS03720	COG0640	Transcriptional regulator
HV042_RS03735	COG4373	Mu-like prophage FluMu protein gp28
HV042_RS03755	COG4397	Mu-like prophage major head subunit gpT
HV042_RS03785	COG4386	tail sheath protein
HV042_RS03795	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
HV042_RS03815	COG4384	Bacteriophage Mu Gp45 protein
HV042_RS03825	COG3299	homolog of phage Mu protein gp47
HV042_RS03835	COG5301	cellulose 1,4-beta-cellobiosidase activity
HV042_RS03840	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HV042_RS03845	COG5301	cellulose 1,4-beta-cellobiosidase activity
HV042_RS03855	COG3384	dioxygenase
HV042_RS03860	COG0754	glutathionylspermidine amidase activity
HV042_RS03875	COG0494	nUDIX hydrolase
HV042_RS03880	COG3151	Protein conserved in bacteria
HV042_RS03885	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HV042_RS03890	COG3150	esterase
HV042_RS03895	COG0187	DNA topoisomerase II activity
HV042_RS03910	COG2211	Major facilitator Superfamily
HV042_RS03915	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV042_RS03920	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HV042_RS03925	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV042_RS03930	COG0642	Histidine kinase
HV042_RS03940	COG3111	PFAM Bacterial OB fold (BOF) protein
HV042_RS03950	COG0204	Acyl-transferase
HV042_RS03955	COG2132	Multicopper oxidase
HV042_RS03960	COG1032	radical SAM domain protein
HV042_RS03970	COG1979	alcohol dehydrogenase
HV042_RS03975	COG2207	Transcriptional regulator
HV042_RS03980	COG0586	Pfam SNARE associated Golgi protein
HV042_RS03995	COG0848	biopolymer transport protein
HV042_RS04015	COG0625	glutathione transferase activity
HV042_RS04025	COG0754	glutathionylspermidine amidase activity
HV042_RS04030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV042_RS04055	COG0626	cystathionine gamma-synthase activity
HV042_RS04065	COG0471	metal ion transport
HV042_RS04075	COG1811	Na channel or pump
HV042_RS04080	COG1982	Orn Lys Arg decarboxylase major
HV042_RS04085	COG2211	Major facilitator Superfamily
HV042_RS04100	COG1194	a g-specific adenine glycosylase
HV042_RS04110	COG3171	Protein conserved in bacteria
HV042_RS04125	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HV042_RS04130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HV042_RS04135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV042_RS04150	COG0762	integral membrane protein
HV042_RS04155	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HV042_RS04160	COG2805	Type II/IV secretion system protein
HV042_RS04165	COG2197	response regulator
HV042_RS04185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HV042_RS04190	COG2356	endonuclease I
HV042_RS04200	COG2814	Major facilitator Superfamily
HV042_RS04220	COG1166	arginine decarboxylase activity
HV042_RS04230	COG0501	Belongs to the peptidase M48B family
HV042_RS04235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV042_RS04240	COG1122	ATPase activity
HV042_RS04245	COG1122	ATPase activity
HV042_RS04275	COG0191	fructose-bisphosphate aldolase activity
HV042_RS04280	COG0668	transmembrane transport
HV042_RS04290	COG2968	Membrane
HV042_RS04295	COG0583	DNA-binding transcription factor activity
HV042_RS04300	COG0427	acetyl-CoA hydrolase
HV042_RS04305	COG1024	Enoyl-CoA hydratase
HV042_RS04310	COG1703	isobutyryl-CoA mutase activity
HV042_RS04330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV042_RS04335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HV042_RS04355	COG0006	proline dipeptidase activity
HV042_RS04360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV042_RS04365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV042_RS04385	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS04390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HV042_RS04395	COG2723	6-phospho-beta-galactosidase activity
HV042_RS04400	COG1737	Transcriptional regulator
HV042_RS04410	COG1272	protein, Hemolysin III
HV042_RS04420	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HV042_RS04430	COG0716	FMN binding
HV042_RS04445	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HV042_RS04465	COG1811	Na channel or pump
HV042_RS04475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV042_RS04480	COG0583	DNA-binding transcription factor activity
HV042_RS04485	COG4942	peptidase
HV042_RS04500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV042_RS04510	COG2814	Major facilitator Superfamily
HV042_RS04520	COG2223	nitrite transmembrane transporter activity
HV042_RS04530	COG1929	Belongs to the glycerate kinase type-1 family
HV042_RS04575	COG0738	Major facilitator superfamily
HV042_RS04580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV042_RS04585	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV042_RS04590	COG1349	DNA-binding transcription factor activity
HV042_RS04615	COG1904	glucuronate isomerase
HV042_RS04620	COG1312	Catalyzes the dehydration of D-mannonate
HV042_RS04625	COG3104	oligopeptide transport
HV042_RS04635	COG2909	trisaccharide binding
HV042_RS04640	COG1538	Outer membrane efflux protein
HV042_RS04645	COG1289	transmembrane transporter activity
HV042_RS04660	COG3592	Divergent 4Fe-4S mono-cluster
HV042_RS04665	COG2388	GCN5-related N-acetyl-transferase
HV042_RS04675	COG3539	Fimbrial protein
HV042_RS04680	COG3539	Fimbrial protein
HV042_RS04685	COG3539	Fimbrial protein
HV042_RS04690	COG3188	usher protein
HV042_RS04695	COG3121	Chaperone
HV042_RS04700	COG3539	Fimbrial protein
HV042_RS04710	COG4974	Belongs to the 'phage' integrase family
HV042_RS04715	COG0582	viral genome integration into host DNA
HV042_RS04725	COG1522	sequence-specific DNA binding
HV042_RS04730	COG1846	Transcriptional regulator
HV042_RS04735	COG0697	spore germination
HV042_RS04795	COG0667	Aldo Keto reductase
HV042_RS04800	COG0814	amino acid
HV042_RS04815	COG0183	Belongs to the thiolase family
HV042_RS04825	COG0823	Involved in the tonB-independent uptake of proteins
HV042_RS04830	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS04835	COG2814	Major facilitator Superfamily
HV042_RS04860	COG0823	Involved in the tonB-independent uptake of proteins
HV042_RS04870	COG3842	ATPase activity
HV042_RS04875	COG0395	ABC-type sugar transport system, permease component
HV042_RS04880	COG1175	transmembrane transport
HV042_RS04890	COG1794	racemase activity, acting on amino acids and derivatives
HV042_RS04895	COG0583	DNA-binding transcription factor activity
HV042_RS04905	COG1609	Transcriptional regulator
HV042_RS04910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV042_RS04915	COG2723	6-phospho-beta-galactosidase activity
HV042_RS04920	COG2186	Transcriptional regulator
HV042_RS04930	COG1609	Transcriptional regulator
HV042_RS04945	COG0667	Aldo Keto reductase
HV042_RS04955	COG0861	Integral membrane protein TerC family
HV042_RS04985	COG2165	general secretion pathway protein
HV042_RS04990	COG4795	General secretion pathway protein
HV042_RS05000	COG4967	type IV pilus modification protein PilV
HV042_RS05005	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HV042_RS05010	COG1025	Belongs to the peptidase M16 family
HV042_RS05015	COG1074	ATP-dependent DNA helicase activity
HV042_RS05020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HV042_RS05025	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HV042_RS05025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HV042_RS05030	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV042_RS05035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HV042_RS05065	COG4656	Part of a membrane complex involved in electron transport
HV042_RS05070	COG1454	alcohol dehydrogenase
HV042_RS05100	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HV042_RS05265	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HV042_RS05270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HV042_RS05275	COG2166	iron-sulfur cluster assembly
HV042_RS05280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HV042_RS05290	COG0583	DNA-binding transcription factor activity
HV042_RS05295	COG2363	Small membrane protein
HV042_RS05305	COG1349	DNA-binding transcription factor activity
HV042_RS05325	COG0738	Major facilitator superfamily
HV042_RS05330	COG0235	Class ii aldolase
HV042_RS05345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV042_RS05360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV042_RS05365	COG1760	l-serine dehydratase
HV042_RS05370	COG0814	amino acid
HV042_RS05375	COG1611	Belongs to the LOG family
HV042_RS05390	COG3098	single-species biofilm formation
HV042_RS05395	COG0564	pseudouridine synthase activity
HV042_RS05400	COG0716	FMN binding
HV042_RS05405	COG2271	Major facilitator Superfamily
HV042_RS05410	COG4948	Mandelate Racemase Muconate Lactonizing
HV042_RS05415	COG4948	Mandelate Racemase Muconate Lactonizing
HV042_RS05420	COG1929	Belongs to the glycerate kinase type-1 family
HV042_RS05425	COG4999	Histidine kinase
HV042_RS05425	COG3850	Histidine kinase
HV042_RS05425	COG3437	response regulator, receiver
HV042_RS05425	COG2205	protein histidine kinase activity
HV042_RS05435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV042_RS05440	COG3956	TIGRFAM MazG family protein
HV042_RS05460	COG0602	queuosine metabolic process
HV042_RS05465	COG0720	synthase
HV042_RS05485	COG1203	CRISPR-associated helicase, Cas3
HV042_RS05500	COG1857	crispr-associated protein
HV042_RS05515	COG1518	maintenance of DNA repeat elements
HV042_RS05520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV042_RS05525	COG2234	aminopeptidase activity
HV042_RS05585	COG4942	peptidase
HV042_RS05585	COG1388	LysM domain
HV042_RS05590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HV042_RS05620	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV042_RS05655	COG0583	DNA-binding transcription factor activity
HV042_RS05670	COG3039	Transposase
HV042_RS05685	COG0582	viral genome integration into host DNA
HV042_RS05690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HV042_RS05700	COG3547	Transposase (IS116 IS110 IS902 family)
HV042_RS05720	COG3423	Transcriptional regulator
HV042_RS05735	COG2003	Belongs to the UPF0758 family
HV042_RS05755	COG4974	Belongs to the 'phage' integrase family
HV042_RS05775	COG3328	transposase activity
HV042_RS05780	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HV042_RS05790	COG3586	endonuclease activity
HV042_RS05795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HV042_RS05810	COG3539	Fimbrial protein
HV042_RS05820	COG3188	usher protein
HV042_RS05825	COG3121	Chaperone
HV042_RS05835	COG3539	Fimbrial protein
HV042_RS05840	COG3539	Fimbrial protein
HV042_RS05865	COG1132	(ABC) transporter
HV042_RS05870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV042_RS05880	COG1538	Outer membrane efflux protein
HV042_RS05885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV042_RS05925	COG1454	alcohol dehydrogenase
HV042_RS05930	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HV042_RS05935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV042_RS05940	COG4558	Periplasmic binding protein
HV042_RS05945	COG3720	iron ion transport
HV042_RS05965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV042_RS05970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV042_RS05975	COG1121	(ABC) transporter
HV042_RS05985	COG1609	Transcriptional regulator
HV042_RS05990	COG1940	carbohydrate kinase activity
HV042_RS05995	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV042_RS06000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV042_RS06005	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV042_RS06010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV042_RS06025	COG2723	6-phospho-beta-galactosidase activity
HV042_RS06030	COG2755	lipolytic protein G-D-S-L family
HV042_RS06030	COG0657	acetylesterase activity
HV042_RS06040	COG0309	Hydrogenase expression formation protein (HypE)
HV042_RS06045	COG0409	Hydrogenase expression formation protein
HV042_RS06050	COG0298	carbon dioxide binding
HV042_RS06055	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HV042_RS06070	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV042_RS06075	COG0651	ATP synthesis coupled electron transport
HV042_RS06080	COG0650	Formate hydrogenlyase subunit 4
HV042_RS06085	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HV042_RS06085	COG3261	NADH dehydrogenase
HV042_RS06090	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV042_RS06095	COG3260	NADH ubiquinone oxidoreductase 20
HV042_RS06105	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HV042_RS06110	COG2723	6-phospho-beta-galactosidase activity
HV042_RS06115	COG1263	PTS System
HV042_RS06115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV042_RS06120	COG1609	Transcriptional regulator
HV042_RS06125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV042_RS06130	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HV042_RS06135	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HV042_RS06160	COG1349	DNA-binding transcription factor activity
HV042_RS06165	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS06170	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS06180	COG3732	PTS system glucitol sorbitol-specific
HV042_RS06185	COG3730	PTS system glucitol sorbitol-specific
HV042_RS06190	COG2951	lytic endotransglycosylase activity
HV042_RS06205	COG0803	Belongs to the bacterial solute-binding protein 9 family
HV042_RS06210	COG1546	Belongs to the CinA family
HV042_RS06230	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HV042_RS06260	COG2823	Periplasmic or secreted lipoprotein
HV042_RS06265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV042_RS06270	COG1238	metal cluster binding
HV042_RS06290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HV042_RS06295	COG2814	Major facilitator Superfamily
HV042_RS06300	COG1566	PFAM secretion protein HlyD family protein
HV042_RS06305	COG1846	Transcriptional regulator
HV042_RS06315	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV042_RS06320	COG2113	Glycine betaine
HV042_RS06325	COG4176	ABC-type proline glycine betaine transport system permease component
HV042_RS06335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV042_RS06340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV042_RS06350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV042_RS06355	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV042_RS06365	COG4575	ribosome binding
HV042_RS06390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV042_RS06395	COG0640	Transcriptional regulator
HV042_RS06400	COG3284	Transcriptional regulator
HV042_RS06405	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS06420	COG3188	usher protein
HV042_RS06445	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS06450	COG2814	Major facilitator Superfamily
HV042_RS06465	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS06475	COG0235	Class ii aldolase
HV042_RS06480	COG1126	abc transporter atp-binding protein
HV042_RS06485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV042_RS06525	COG4974	Belongs to the 'phage' integrase family
HV042_RS06590	COG4695	Portal protein
HV042_RS06725	COG2867	negative regulation of translational initiation
HV042_RS06740	COG0497	DNA recombination
HV042_RS06755	COG4536	flavin adenine dinucleotide binding
HV042_RS06760	COG4137	Cytochrome C assembly protein
HV042_RS06765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HV042_RS06800	COG2885	chlorophyll binding
HV042_RS06805	COG2199	diguanylate cyclase activity
HV042_RS06815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV042_RS06820	COG1605	Chorismate mutase
HV042_RS06820	COG0287	Prephenate dehydrogenase
HV042_RS06830	COG0077	Prephenate dehydratase
HV042_RS06830	COG1605	Chorismate mutase
HV042_RS06835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV042_RS06840	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV042_RS06855	COG0542	response to heat
HV042_RS06880	COG0477	Major facilitator Superfamily
HV042_RS06885	COG5544	Lipoprotein
HV042_RS06890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV042_RS06905	COG3118	belongs to the thioredoxin family
HV042_RS06910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV042_RS06925	COG0513	Belongs to the DEAD box helicase family
HV042_RS06935	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HV042_RS06950	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HV042_RS06960	COG3086	response to oxidative stress
HV042_RS06970	COG0681	Belongs to the peptidase S26 family
HV042_RS06990	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HV042_RS07000	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV042_RS07005	COG1737	Transcriptional regulator
HV042_RS07010	COG0560	Phosphoserine phosphatase
HV042_RS07025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HV042_RS07025	COG0047	phosphoribosylformylglycinamidine synthase activity
HV042_RS07030	COG2205	protein histidine kinase activity
HV042_RS07035	COG3170	Tfp pilus assembly protein FimV
HV042_RS07040	COG2204	response regulator
HV042_RS07045	COG0347	Belongs to the P(II) protein family
HV042_RS07060	COG2259	Doxx family
HV042_RS07065	COG1940	carbohydrate kinase activity
HV042_RS07070	COG0457	Tetratricopeptide repeat
HV042_RS07075	COG0477	Major facilitator Superfamily
HV042_RS07075	COG2814	Major facilitator Superfamily
HV042_RS07080	COG2017	converts alpha-aldose to the beta-anomer
HV042_RS07085	COG2814	Major facilitator Superfamily
HV042_RS07090	COG3711	transcriptional antiterminator
HV042_RS07095	COG3683	transport system, periplasmic component
HV042_RS07100	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HV042_RS07125	COG0822	iron-sulfur transferase activity
HV042_RS07145	COG0633	Ferredoxin
HV042_RS07150	COG2975	iron-sulfur cluster assembly
HV042_RS07165	COG2897	thiosulfate sulfurtransferase activity
HV042_RS07170	COG2373	Large extracellular alpha-helical protein
HV042_RS07175	COG4953	penicillin-binding protein 1C
HV042_RS07205	COG2976	Protein conserved in bacteria
HV042_RS07230	COG1645	bacterial-type flagellum-dependent swarming motility
HV042_RS07245	COG1570	exodeoxyribonuclease VII activity
HV042_RS07250	COG0516	GMP reductase activity
HV042_RS07250	COG0517	IMP dehydrogenase activity
HV042_RS07255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HV042_RS07255	COG0519	Catalyzes the synthesis of GMP from XMP
HV042_RS07265	COG0583	DNA-binding transcription factor activity
HV042_RS07275	COG2200	EAL domain
HV042_RS07280	COG0248	Ppx GppA phosphatase
HV042_RS07300	COG2211	Major facilitator Superfamily
HV042_RS07310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HV042_RS07325	COG2723	6-phospho-beta-galactosidase activity
HV042_RS07330	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HV042_RS07335	COG2233	PERMEase
HV042_RS07345	COG1393	Belongs to the ArsC family
HV042_RS07350	COG4783	chaperone-mediated protein folding
HV042_RS07355	COG0628	permease
HV042_RS07360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HV042_RS07365	COG2716	regulation of RNA biosynthetic process
HV042_RS07375	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HV042_RS07385	COG2321	neutral zinc metallopeptidase
HV042_RS07395	COG0400	carboxylic ester hydrolase activity
HV042_RS07410	COG1393	Belongs to the ArsC family
HV042_RS07420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV042_RS07425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV042_RS07425	COG0493	'glutamate synthase
HV042_RS07435	COG5342	invasion associated locus B
HV042_RS07440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV042_RS07450	COG4810	utilization protein
HV042_RS07460	COG4766	ethanolamine catabolic process
HV042_RS07530	COG2207	Transcriptional regulator
HV042_RS07540	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV042_RS07560	COG2837	iron assimilation
HV042_RS07565	COG4150	thiosulfate binding
HV042_RS07570	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HV042_RS07575	COG4208	sulfate ABC transporter
HV042_RS07580	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HV042_RS07590	COG4319	ketosteroid isomerase
HV042_RS07630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HV042_RS07650	COG3530	Putative quorum-sensing-regulated virulence factor
HV042_RS07655	COG0385	Bile acid
HV042_RS07660	COG0583	DNA-binding transcription factor activity
HV042_RS07665	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HV042_RS07670	COG2211	Major facilitator Superfamily
HV042_RS07675	COG0583	DNA-binding transcription factor activity
HV042_RS07705	COG3415	Transposase
HV042_RS07710	COG3415	Transposase
HV042_RS07725	COG2200	EAL domain
HV042_RS07725	COG2199	diguanylate cyclase activity
HV042_RS07730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV042_RS07745	COG0667	Aldo Keto reductase
HV042_RS07750	COG3961	Belongs to the TPP enzyme family
HV042_RS07765	COG3279	Response regulator of the LytR AlgR family
HV042_RS07770	COG3275	phosphorelay sensor kinase activity
HV042_RS07775	COG0436	Aminotransferase
HV042_RS07850	COG0582	viral genome integration into host DNA
HV042_RS07860	COG0582	viral genome integration into host DNA
HV042_RS07920	COG1061	Type III restriction enzyme res subunit
HV042_RS07970	COG3179	chitinase
HV042_RS08010	COG1802	Transcriptional regulator
HV042_RS08010	COG4626	Terminase
HV042_RS08020	COG4695	Portal protein
HV042_RS08135	COG2116	formate transmembrane transporter activity
HV042_RS08150	COG3691	Protein conserved in bacteria
HV042_RS08165	COG2062	phosphohistidine phosphatase, SixA
HV042_RS08190	COG0730	response to heat
HV042_RS08195	COG3101	peptidyl-lysine hydroxylation
HV042_RS08210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV042_RS08230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV042_RS08240	COG0586	Pfam SNARE associated Golgi protein
HV042_RS08250	COG0285	dihydrofolate synthase activity
HV042_RS08255	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HV042_RS08260	COG1286	toxin biosynthetic process
HV042_RS08265	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HV042_RS08270	COG0163	prenyltransferase activity
HV042_RS08290	COG4160	amino acid transport
HV042_RS08295	COG4598	ABC transporter
HV042_RS08315	COG1090	epimerase
HV042_RS08320	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV042_RS08325	COG0625	glutathione transferase activity
HV042_RS08330	COG0625	glutathione transferase activity
HV042_RS08335	COG0622	Phosphoesterase
HV042_RS08345	COG1609	Transcriptional regulator
HV042_RS08350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS08360	COG3037	sugar-specific permease SgaT UlaA
HV042_RS08365	COG3959	Transketolase, thiamine diphosphate binding domain
HV042_RS08370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HV042_RS08395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV042_RS08400	COG0471	metal ion transport
HV042_RS08400	COG0490	domain, Protein
HV042_RS08410	COG0436	Aminotransferase
HV042_RS08415	COG0583	DNA-binding transcription factor activity
HV042_RS08460	COG0839	Belongs to the complex I subunit 6 family
HV042_RS08465	COG0713	ATP synthesis coupled electron transport
HV042_RS08470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HV042_RS08475	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV042_RS08485	COG0582	viral genome integration into host DNA
HV042_RS08515	COG0582	viral genome integration into host DNA
HV042_RS08525	COG2153	protein acetylation
HV042_RS08530	COG1169	isochorismate synthase
HV042_RS08560	COG3647	Membrane
HV042_RS08585	COG0642	Histidine kinase
HV042_RS08615	COG1414	Transcriptional regulator
HV042_RS08625	COG2271	Major facilitator Superfamily
HV042_RS08635	COG0247	lactate metabolic process
HV042_RS08645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV042_RS08650	COG2271	Major facilitator Superfamily
HV042_RS08655	COG0584	glycerophosphoryl diester phosphodiesterase
HV042_RS08660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV042_RS08685	COG0784	Response regulator, receiver
HV042_RS08685	COG2205	protein histidine kinase activity
HV042_RS08695	COG2198	Histidine kinase
HV042_RS08695	COG0642	Histidine kinase
HV042_RS08710	COG2169	Transcriptional regulator
HV042_RS08710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HV042_RS08720	COG4615	Cyclic peptide transporter
HV042_RS08725	COG2239	Acts as a magnesium transporter
HV042_RS08730	COG0659	secondary active sulfate transmembrane transporter activity
HV042_RS08750	COG0628	permease
HV042_RS08775	COG1349	DNA-binding transcription factor activity
HV042_RS08780	COG0494	nUDIX hydrolase
HV042_RS08790	COG1061	Type III restriction enzyme res subunit
HV042_RS08795	COG1187	pseudouridine synthase activity
HV042_RS08800	COG2814	Major facilitator Superfamily
HV042_RS08810	COG4172	Belongs to the ABC transporter superfamily
HV042_RS08815	COG4239	(ABC) transporter, permease
HV042_RS08820	COG4174	ABC transporter (Permease)
HV042_RS08825	COG4166	transmembrane transport
HV042_RS08830	COG2200	EAL domain
HV042_RS08835	COG0791	NLP P60 protein
HV042_RS08840	COG0671	phosphoesterase, PA-phosphatase related
HV042_RS08845	COG0523	cobalamin synthesis protein
HV042_RS08850	COG0246	Mannitol dehydrogenase
HV042_RS08855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HV042_RS08865	COG2814	Major facilitator Superfamily
HV042_RS08870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS08870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS08875	COG1105	Belongs to the carbohydrate kinase PfkB family
HV042_RS08880	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HV042_RS08880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV042_RS08880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV042_RS08885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV042_RS08890	COG2313	pseudouridylate synthase activity
HV042_RS08895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV042_RS08900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV042_RS08900	COG1522	sequence-specific DNA binding
HV042_RS08910	COG2855	membrane
HV042_RS08915	COG0583	DNA-binding transcription factor activity
HV042_RS08920	COG0833	amino acid
HV042_RS08925	COG4771	TonB-dependent receptor
HV042_RS08940	COG2311	Membrane
HV042_RS08955	COG1129	ABC transporter
HV042_RS08980	COG2949	membrane
HV042_RS08990	COG1346	cytolysis
HV042_RS09000	COG0583	DNA-binding transcription factor activity
HV042_RS09005	COG2271	Major facilitator Superfamily
HV042_RS09020	COG0625	glutathione transferase activity
HV042_RS09025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV042_RS09030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV042_RS09035	COG3711	transcriptional antiterminator
HV042_RS09045	COG2723	6-phospho-beta-galactosidase activity
HV042_RS09050	COG2226	methyltransferase
HV042_RS09055	COG1538	Outer membrane efflux protein
HV042_RS09060	COG0586	Pfam SNARE associated Golgi protein
HV042_RS09070	COG1686	Belongs to the peptidase S11 family
HV042_RS09080	COG0277	FAD linked oxidase domain protein
HV042_RS09085	COG1472	Belongs to the glycosyl hydrolase 3 family
HV042_RS09090	COG1732	Glycine betaine
HV042_RS09095	COG1174	glycine betaine transport
HV042_RS09100	COG1125	glycine betaine transport
HV042_RS09105	COG1174	glycine betaine transport
HV042_RS09115	COG0789	Transcriptional regulator
HV042_RS09120	COG3275	phosphorelay sensor kinase activity
HV042_RS09130	COG4807	Protein conserved in bacteria
HV042_RS09135	COG4808	Protein conserved in bacteria
HV042_RS09140	COG4715	Zinc finger, swim domain protein
HV042_RS09145	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HV042_RS09150	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HV042_RS09155	COG0714	Associated with various cellular activities
HV042_RS09160	COG3831	ATPase activity
HV042_RS09165	COG3831	ATPase activity
HV042_RS09175	COG0489	protein tyrosine kinase activity
HV042_RS09185	COG5455	response to cobalt ion
HV042_RS09190	COG0583	DNA-binding transcription factor activity
HV042_RS09195	COG2252	PERMEase
HV042_RS09205	COG0583	DNA-binding transcription factor activity
HV042_RS09210	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HV042_RS09220	COG0351	phosphomethylpyrimidine kinase
HV042_RS09225	COG1830	Aldolase
HV042_RS09255	COG1070	Carbohydrate kinase
HV042_RS09265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV042_RS09270	COG4948	Mandelate Racemase Muconate Lactonizing
HV042_RS09275	COG0747	negative chemotaxis
HV042_RS09280	COG0601	transmembrane transport
HV042_RS09290	COG0444	Belongs to the ABC transporter superfamily
HV042_RS09295	COG4608	Belongs to the ABC transporter superfamily
HV042_RS09320	COG0745	RESPONSE REGULATOR receiver
HV042_RS09325	COG2205	protein histidine kinase activity
HV042_RS09355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV042_RS09370	COG1522	sequence-specific DNA binding
HV042_RS09380	COG2267	carboxylic ester hydrolase activity
HV042_RS09395	COG0601	transmembrane transport
HV042_RS09400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV042_RS09405	COG0444	Belongs to the ABC transporter superfamily
HV042_RS09410	COG4608	Belongs to the ABC transporter superfamily
HV042_RS09420	COG1301	dicarboxylic acid transport
HV042_RS09445	COG0243	molybdopterin cofactor binding
HV042_RS09445	COG3383	formate dehydrogenase (NAD+) activity
HV042_RS09450	COG0437	4 iron, 4 sulfur cluster binding
HV042_RS09455	COG2864	formate dehydrogenase
HV042_RS09460	COG0372	Belongs to the citrate synthase family
HV042_RS09465	COG0443	Heat shock 70 kDa protein
HV042_RS09470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HV042_RS09485	COG2982	Protein involved in outer membrane biogenesis
HV042_RS09490	COG1253	flavin adenine dinucleotide binding
HV042_RS09535	COG0438	transferase activity, transferring glycosyl groups
HV042_RS09555	COG2244	polysaccharide biosynthetic process
HV042_RS09565	COG1215	transferase activity, transferring glycosyl groups
HV042_RS09630	COG1216	Glycosyl transferase, family 2
HV042_RS09640	COG0107	imidazoleglycerol-phosphate synthase activity
HV042_RS09650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HV042_RS09665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HV042_RS09680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV042_RS09685	COG0583	DNA-binding transcription factor activity
HV042_RS09695	COG0531	amino acid
HV042_RS09715	COG2205	protein histidine kinase activity
HV042_RS09800	COG0640	Transcriptional regulator
HV042_RS09805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HV042_RS09810	COG2925	Exonuclease
HV042_RS09830	COG1289	transmembrane transporter activity
HV042_RS09850	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HV042_RS09860	COG1942	4-Oxalocrotonate Tautomerase
HV042_RS09865	COG0583	DNA-binding transcription factor activity
HV042_RS09870	COG0095	Lipoate-protein ligase
HV042_RS09875	COG0477	Major facilitator Superfamily
HV042_RS09885	COG3300	MHYT domain
HV042_RS09885	COG5001	Diguanylate cyclase
HV042_RS09890	COG3615	Tellurite resistance protein tehB
HV042_RS09900	COG2188	Transcriptional regulator
HV042_RS09905	COG1263	PTS System
HV042_RS09905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV042_RS09920	COG3539	Fimbrial protein
HV042_RS09925	COG3539	Fimbrial protein
HV042_RS09930	COG3539	Fimbrial protein
HV042_RS09935	COG3188	usher protein
HV042_RS09940	COG3121	Chaperone
HV042_RS09945	COG3539	Fimbrial protein
HV042_RS09955	COG2197	response regulator
HV042_RS09975	COG1376	ErfK ybiS ycfS ynhG family protein
HV042_RS09990	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HV042_RS09995	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HV042_RS10010	COG0642	Histidine kinase
HV042_RS10025	COG3423	Transcriptional regulator
HV042_RS10045	COG0534	Mate efflux family protein
HV042_RS10055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HV042_RS10085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV042_RS10095	COG0589	response to stress
HV042_RS10125	COG0251	oxidation-reduction process
HV042_RS10155	COG0463	Glycosyl transferase, family 2
HV042_RS10165	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV042_RS10175	COG1418	mRNA catabolic process
HV042_RS10180	COG0270	DNA (cytosine-5-)-methyltransferase activity
HV042_RS10185	COG3727	T/G mismatch-specific endonuclease activity
HV042_RS10190	COG0697	spore germination
HV042_RS10195	COG2354	Protein conserved in bacteria
HV042_RS10200	COG5475	Uncharacterized small protein (DUF2158)
HV042_RS10230	COG0366	Alpha amylase catalytic
HV042_RS10255	COG2197	response regulator
HV042_RS10265	COG2197	response regulator
HV042_RS10350	COG0305	Participates in initiation and elongation during chromosome replication
HV042_RS10530	COG3772	lysozyme
HV042_RS10540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV042_RS10545	COG3012	SEC-C Motif Domain Protein
HV042_RS10545	COG3318	Belongs to the UPF0149 family
HV042_RS10550	COG0814	amino acid
HV042_RS10560	COG1528	Iron-storage protein
HV042_RS10570	COG0477	Major facilitator Superfamily
HV042_RS10600	COG1879	ABC-type sugar transport system periplasmic component
HV042_RS10610	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS10640	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV042_RS10650	COG3102	Protein conserved in bacteria
HV042_RS10670	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HV042_RS10675	COG1801	Protein of unknown function DUF72
HV042_RS10680	COG1335	isochorismatase
HV042_RS10690	COG0494	nUDIX hydrolase
HV042_RS10695	COG0217	transcriptional regulatory protein
HV042_RS10715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV042_RS10725	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HV042_RS10730	COG0739	heme binding
HV042_RS10735	COG1560	Kdo2-lipid A biosynthetic process
HV042_RS10745	COG1737	Transcriptional regulator
HV042_RS10750	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HV042_RS10755	COG0129	dihydroxy-acid dehydratase activity
HV042_RS10760	COG0800	Aldolase
HV042_RS10770	COG3141	response to X-ray
HV042_RS10775	COG2979	Protein of unknown function (DUF533)
HV042_RS10780	COG1770	oligopeptidase
HV042_RS10785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV042_RS10795	COG2372	response to copper ion
HV042_RS10800	COG1276	copper resistance
HV042_RS10840	COG2990	Protein conserved in bacteria
HV042_RS10845	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HV042_RS10865	COG3008	intermembrane lipid transfer
HV042_RS10870	COG2995	paraquat-inducible protein a
HV042_RS10875	COG1956	GAF domain-containing protein
HV042_RS10895	COG2814	Major facilitator Superfamily
HV042_RS10900	COG1414	Transcriptional regulator
HV042_RS10930	COG0768	penicillin binding
HV042_RS10935	COG2226	methyltransferase
HV042_RS10950	COG3716	PTS system mannose fructose sorbose family IID component
HV042_RS10955	COG3715	PTS system
HV042_RS10960	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS10960	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV042_RS10965	COG1253	flavin adenine dinucleotide binding
HV042_RS10970	COG2200	EAL domain
HV042_RS10975	COG1760	l-serine dehydratase
HV042_RS11005	COG1653	transport
HV042_RS11010	COG1175	transmembrane transport
HV042_RS11015	COG0395	ABC-type sugar transport system, permease component
HV042_RS11020	COG3842	ATPase activity
HV042_RS11030	COG0251	oxidation-reduction process
HV042_RS11035	COG1199	ATP-dependent helicase activity
HV042_RS11040	COG1214	PFAM Peptidase M22, glycoprotease
HV042_RS11045	COG3065	identical protein binding
HV042_RS11055	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HV042_RS11065	COG2894	cell division
HV042_RS11080	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV042_RS11110	COG2719	SpoVR family
HV042_RS11130	COG1619	proteins homologs of microcin C7 resistance protein MccF
HV042_RS11155	COG2211	Major facilitator Superfamily
HV042_RS11165	COG1472	Belongs to the glycosyl hydrolase 3 family
HV042_RS11170	COG2308	Evidence 4 Homologs of previously reported genes of
HV042_RS11195	COG2814	Major facilitator Superfamily
HV042_RS11210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV042_RS11220	COG1174	glycine betaine transport
HV042_RS11235	COG0564	pseudouridine synthase activity
HV042_RS11240	COG0583	DNA-binding transcription factor activity
HV042_RS11245	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HV042_RS11260	COG2351	hydroxyisourate hydrolase activity
HV042_RS11265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS11265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS11270	COG2814	Major facilitator Superfamily
HV042_RS11285	COG2068	MobA-Related Protein
HV042_RS11295	COG2233	PERMEase
HV042_RS11305	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV042_RS11310	COG0402	S-adenosylhomocysteine deaminase activity
HV042_RS11315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV042_RS11315	COG0493	'glutamate synthase
HV042_RS11320	COG3608	succinylglutamate desuccinylase aspartoacylase
HV042_RS11320	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HV042_RS11325	COG0549	Belongs to the carbamate kinase family
HV042_RS11335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV042_RS11340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV042_RS11345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HV042_RS11355	COG0012	GTP binding
HV042_RS11375	COG0659	secondary active sulfate transmembrane transporter activity
HV042_RS11405	COG2890	protein-(glutamine-N5) methyltransferase activity
HV042_RS11425	COG0387	Pfam Sodium calcium exchanger
HV042_RS11430	COG4572	Cation transport regulator
HV042_RS11435	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HV042_RS11445	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HV042_RS11450	COG3707	response regulator
HV042_RS11455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV042_RS11465	COG1116	anion transmembrane transporter activity
HV042_RS11470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV042_RS11470	COG2146	nitrite reductase [NAD(P)H] activity
HV042_RS11475	COG0243	molybdopterin cofactor binding
HV042_RS11480	COG4932	domain protein
HV042_RS11485	COG2197	response regulator
HV042_RS11490	COG3850	Histidine kinase
HV042_RS11495	COG2223	nitrite transmembrane transporter activity
HV042_RS11500	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV042_RS11505	COG1140	nitrate reductase beta subunit
HV042_RS11510	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV042_RS11515	COG2181	nitrate reductase activity
HV042_RS11525	COG1522	sequence-specific DNA binding
HV042_RS11545	COG0788	formyltetrahydrofolate deformylase activity
HV042_RS11555	COG1752	Esterase of the alpha-beta hydrolase superfamily
HV042_RS11560	COG0745	RESPONSE REGULATOR receiver
HV042_RS11565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HV042_RS11575	COG3039	Transposase
HV042_RS11585	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS11585	COG1454	alcohol dehydrogenase
HV042_RS11590	COG2095	MarC family integral membrane protein
HV042_RS11600	COG0601	transmembrane transport
HV042_RS11605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV042_RS11610	COG0444	Belongs to the ABC transporter superfamily
HV042_RS11620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV042_RS11640	COG2350	Protein conserved in bacteria
HV042_RS11645	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HV042_RS11650	COG3001	Fructosamine kinase
HV042_RS11660	COG1105	Belongs to the carbohydrate kinase PfkB family
HV042_RS11665	COG3137	Salt-induced outer membrane protein
HV042_RS11690	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HV042_RS11705	COG0072	phenylalanine-tRNA ligase activity
HV042_RS11705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HV042_RS11725	COG0386	Belongs to the glutathione peroxidase family
HV042_RS11735	COG0791	NLP P60 protein
HV042_RS11745	COG4256	Hemin uptake protein
HV042_RS11750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV042_RS11760	COG0574	Belongs to the PEP-utilizing enzyme family
HV042_RS11760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV042_RS11770	COG0628	permease
HV042_RS11775	COG0277	FAD linked oxidase domain protein
HV042_RS11775	COG0247	lactate metabolic process
HV042_RS11780	COG2050	protein possibly involved in aromatic compounds catabolism
HV042_RS11785	COG2261	transglycosylase associated protein
HV042_RS11790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV042_RS11805	COG3121	Chaperone
HV042_RS11825	COG0316	Belongs to the HesB IscA family
HV042_RS11830	COG0719	Fe-S assembly protein
HV042_RS11835	COG0396	ATPase activity
HV042_RS11840	COG0719	Fe-S assembly protein
HV042_RS11855	COG1376	ErfK ybiS ycfS ynhG family protein
HV042_RS11885	COG2271	Major facilitator Superfamily
HV042_RS11890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV042_RS11895	COG1414	Transcriptional regulator
HV042_RS11930	COG2814	Major facilitator Superfamily
HV042_RS11955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV042_RS11960	COG1960	acyl-CoA dehydrogenase activity
HV042_RS11975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV042_RS11980	COG1116	anion transmembrane transporter activity
HV042_RS11985	COG4774	siderophore transport
HV042_RS11990	COG1120	ATPase activity
HV042_RS11995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV042_RS12000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV042_RS12020	COG0765	amino acid transport
HV042_RS12025	COG1126	abc transporter atp-binding protein
HV042_RS12045	COG3383	formate dehydrogenase (NAD+) activity
HV042_RS12050	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV042_RS12060	COG1175	transmembrane transport
HV042_RS12065	COG3842	ATPase activity
HV042_RS12090	COG1278	Cold shock
HV042_RS12095	COG0626	cystathionine gamma-synthase activity
HV042_RS12100	COG1757	Na H antiporter
HV042_RS12120	COG4993	Dehydrogenase
HV042_RS12125	COG4608	Belongs to the ABC transporter superfamily
HV042_RS12130	COG0444	Belongs to the ABC transporter superfamily
HV042_RS12145	COG0747	negative chemotaxis
HV042_RS12160	COG2011	ABC-type metal ion transport system permease component
HV042_RS12175	COG0346	lactoylglutathione lyase activity
HV042_RS12180	COG1349	DNA-binding transcription factor activity
HV042_RS12195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV042_RS12200	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS12205	COG3111	PFAM Bacterial OB fold (BOF) protein
HV042_RS12215	COG4529	Protein conserved in bacteria
HV042_RS12230	COG2323	membrane
HV042_RS12235	COG1546	Belongs to the CinA family
HV042_RS12245	COG0366	Alpha amylase catalytic
HV042_RS12250	COG1294	oxidase, subunit
HV042_RS12255	COG1271	oxidase subunit
HV042_RS12260	COG3546	catalase activity
HV042_RS12265	COG3685	Protein conserved in bacteria
HV042_RS12270	COG3685	Protein conserved in bacteria
HV042_RS12275	COG3729	General stress protein
HV042_RS12300	COG0307	riboflavin synthase, alpha
HV042_RS12305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV042_RS12310	COG2814	Major facilitator Superfamily
HV042_RS12315	COG0583	DNA-binding transcription factor activity
HV042_RS12330	COG2814	Major facilitator Superfamily
HV042_RS12335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HV042_RS12365	COG2801	Transposase and inactivated derivatives
HV042_RS12380	COG0791	NLP P60 protein
HV042_RS12385	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HV042_RS12395	COG0346	lactoylglutathione lyase activity
HV042_RS12400	COG1902	pentaerythritol trinitrate reductase activity
HV042_RS12405	COG1309	transcriptional regulator
HV042_RS12410	COG3313	Fe-S protein
HV042_RS12415	COG4989	oxidoreductase activity
HV042_RS12425	COG1289	transmembrane transporter activity
HV042_RS12430	COG1566	PFAM secretion protein HlyD family protein
HV042_RS12445	COG3706	GGDEF domain
HV042_RS12460	COG3895	Periplasmic Protein
HV042_RS12480	COG0625	glutathione transferase activity
HV042_RS12490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HV042_RS12500	COG4659	FMN binding
HV042_RS12535	COG2723	6-phospho-beta-galactosidase activity
HV042_RS12545	COG0673	inositol 2-dehydrogenase activity
HV042_RS12560	COG0425	Belongs to the sulfur carrier protein TusA family
HV042_RS12565	COG2391	methyltransferase activity
HV042_RS12575	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV042_RS12580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV042_RS12580	COG1263	PTS System
HV042_RS12585	COG1609	Transcriptional regulator
HV042_RS12590	COG5339	Protein conserved in bacteria
HV042_RS12600	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV042_RS12600	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV042_RS12605	COG0114	fumarate hydratase activity
HV042_RS12615	COG2205	protein histidine kinase activity
HV042_RS12625	COG0745	RESPONSE REGULATOR receiver
HV042_RS12635	COG3039	Transposase
HV042_RS12640	COG3136	membrane protein required for alginate biosynthesis
HV042_RS12650	COG0531	amino acid
HV042_RS12665	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HV042_RS12670	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HV042_RS12680	COG0589	response to stress
HV042_RS12685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV042_RS12695	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HV042_RS12700	COG1473	amidohydrolase
HV042_RS12710	COG0583	DNA-binding transcription factor activity
HV042_RS12715	COG2840	Smr protein MutS2
HV042_RS12720	COG1414	Transcriptional regulator
HV042_RS12730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HV042_RS12735	COG0183	Belongs to the thiolase family
HV042_RS12745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HV042_RS12750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV042_RS12755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV042_RS12755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV042_RS12775	COG4565	transcriptional regulatory protein
HV042_RS12780	COG3290	protein histidine kinase activity
HV042_RS12790	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS12795	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HV042_RS12810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HV042_RS12820	COG0679	Auxin Efflux Carrier
HV042_RS12850	COG0628	permease
HV042_RS12865	COG3300	MHYT domain
HV042_RS12865	COG5001	Diguanylate cyclase
HV042_RS12870	COG3591	Belongs to the peptidase S1B family
HV042_RS12885	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HV042_RS12890	COG2814	Major facilitator Superfamily
HV042_RS12895	COG0583	DNA-binding transcription factor activity
HV042_RS12900	COG1940	carbohydrate kinase activity
HV042_RS12905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HV042_RS12920	COG3302	dmso reductase anchor subunit
HV042_RS12925	COG0437	4 iron, 4 sulfur cluster binding
HV042_RS12930	COG0243	molybdopterin cofactor binding
HV042_RS12945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV042_RS12960	COG4948	Mandelate Racemase Muconate Lactonizing
HV042_RS12965	COG1063	alcohol dehydrogenase
HV042_RS12970	COG0477	Major facilitator Superfamily
HV042_RS12975	COG0246	Mannitol dehydrogenase
HV042_RS12980	COG0589	response to stress
HV042_RS12985	COG1802	Transcriptional regulator
HV042_RS12990	COG4221	oxidoreductase activity
HV042_RS12995	COG0339	signal peptide processing
HV042_RS13010	COG3122	Protein conserved in bacteria
HV042_RS13035	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HV042_RS13040	COG2223	nitrite transmembrane transporter activity
HV042_RS13060	COG2200	EAL domain
HV042_RS13095	COG3210	domain, Protein
HV042_RS13125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HV042_RS13145	COG1129	ABC transporter
HV042_RS13160	COG2814	Major facilitator Superfamily
HV042_RS13165	COG0697	spore germination
HV042_RS13210	COG2731	YhcH YjgK YiaL family protein
HV042_RS13220	COG0861	Integral membrane protein TerC family
HV042_RS13225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV042_RS13230	COG1454	alcohol dehydrogenase
HV042_RS13235	COG3395	kinase activity
HV042_RS13240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HV042_RS13245	COG1349	DNA-binding transcription factor activity
HV042_RS13250	COG0039	L-malate dehydrogenase activity
HV042_RS13260	COG0583	DNA-binding transcription factor activity
HV042_RS13265	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS13280	COG2199	diguanylate cyclase activity
HV042_RS13325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV042_RS13330	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV042_RS13355	COG3039	Transposase
HV042_RS13360	COG2814	Major facilitator Superfamily
HV042_RS13385	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS13425	COG0477	Major facilitator Superfamily
HV042_RS13440	COG2011	ABC-type metal ion transport system permease component
HV042_RS13460	COG4628	conserved protein (DUF2132)
HV042_RS13475	COG1126	abc transporter atp-binding protein
HV042_RS13480	COG0765	amino acid transport
HV042_RS13485	COG0765	amino acid transport
HV042_RS13505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HV042_RS13510	COG2207	Transcriptional regulator
HV042_RS13520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HV042_RS13525	COG1446	asparaginase
HV042_RS13530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV042_RS13545	COG1120	ATPase activity
HV042_RS13550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV042_RS13555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV042_RS13570	COG3775	system Galactitol-specific IIC component
HV042_RS13575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV042_RS13580	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS13585	COG1070	Carbohydrate kinase
HV042_RS13615	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS13630	COG1609	Transcriptional regulator
HV042_RS13640	COG0693	protein deglycase activity
HV042_RS13655	COG0412	Dienelactone hydrolase
HV042_RS13660	COG0583	DNA-binding transcription factor activity
HV042_RS13685	COG2841	Protein conserved in bacteria
HV042_RS13710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS13725	COG4821	SIS domain
HV042_RS13730	COG2188	Transcriptional regulator
HV042_RS13770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HV042_RS13800	COG3539	Fimbrial protein
HV042_RS13805	COG3121	Chaperone
HV042_RS13810	COG3539	Fimbrial protein
HV042_RS13855	COG3391	amine dehydrogenase activity
HV042_RS13860	COG4771	TonB-dependent receptor
HV042_RS13870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV042_RS13885	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS13895	COG1609	Transcriptional regulator
HV042_RS13930	COG1652	LysM domain
HV042_RS13935	COG4771	TonB-dependent receptor
HV042_RS13940	COG1021	2,3-dihydroxybenzoate-AMP ligase
HV042_RS13975	COG1132	(ABC) transporter
HV042_RS13980	COG2814	Major facilitator Superfamily
HV042_RS13985	COG1169	isochorismate synthase
HV042_RS14010	COG0814	amino acid
HV042_RS14015	COG1760	l-serine dehydratase
HV042_RS14030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HV042_RS14040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV042_RS14045	COG0765	amino acid transport
HV042_RS14050	COG1126	abc transporter atp-binding protein
HV042_RS14060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HV042_RS14065	COG1309	transcriptional regulator
HV042_RS14075	COG2801	Transposase and inactivated derivatives
HV042_RS14085	COG2801	Transposase and inactivated derivatives
HV042_RS14100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HV042_RS14105	COG0022	dehydrogenase e1 component
HV042_RS14110	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV042_RS14115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV042_RS14130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HV042_RS14135	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS14145	COG0401	homolog of Blt101
HV042_RS14155	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV042_RS14160	COG2200	EAL domain
HV042_RS14160	COG2771	luxR family
HV042_RS14210	COG1082	Xylose isomerase domain protein TIM barrel
HV042_RS14215	COG0673	inositol 2-dehydrogenase activity
HV042_RS14220	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HV042_RS14225	COG1116	anion transmembrane transporter activity
HV042_RS14230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV042_RS14235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV042_RS14240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV042_RS14245	COG0076	glutamate decarboxylase activity
HV042_RS14260	COG0519	Catalyzes the synthesis of GMP from XMP
HV042_RS14260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HV042_RS14275	COG0439	Biotin carboxylase
HV042_RS14290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV042_RS14290	COG1116	anion transmembrane transporter activity
HV042_RS14315	COG1280	lysine exporter protein (LysE YggA)
HV042_RS14330	COG0583	DNA-binding transcription factor activity
HV042_RS14350	COG1285	pathogenesis
HV042_RS14360	COG2271	Major facilitator Superfamily
HV042_RS14375	COG0583	DNA-binding transcription factor activity
HV042_RS14385	COG1280	lysine exporter protein (LysE YggA)
HV042_RS14390	COG0243	molybdopterin cofactor binding
HV042_RS14395	COG3781	membrane
HV042_RS14410	COG1764	response to oxidative stress
HV042_RS14420	COG0583	DNA-binding transcription factor activity
HV042_RS14445	COG3039	Transposase
HV042_RS14460	COG0488	(ABC) transporter
HV042_RS14505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV042_RS14515	COG2814	Major facilitator Superfamily
HV042_RS14525	COG2864	formate dehydrogenase
HV042_RS14530	COG0437	4 iron, 4 sulfur cluster binding
HV042_RS14540	COG0697	spore germination
HV042_RS14555	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HV042_RS14565	COG3485	protocatechuate 3,4-dioxygenase
HV042_RS14570	COG4829	muconolactone delta-isomerase
HV042_RS14575	COG4948	Mandelate Racemase Muconate Lactonizing
HV042_RS14580	COG1414	Transcriptional regulator
HV042_RS14595	COG2223	nitrite transmembrane transporter activity
HV042_RS14600	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV042_RS14605	COG1140	nitrate reductase beta subunit
HV042_RS14610	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV042_RS14615	COG2181	nitrate reductase activity
HV042_RS14620	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HV042_RS14625	COG1178	ABC-type Fe3 transport system permease component
HV042_RS14635	COG3842	ATPase activity
HV042_RS14640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV042_RS14645	COG4977	sequence-specific DNA binding
HV042_RS14655	COG2211	Major facilitator Superfamily
HV042_RS14665	COG3039	Transposase
HV042_RS14685	COG0625	glutathione transferase activity
HV042_RS14690	COG1609	Transcriptional regulator
HV042_RS14710	COG1126	abc transporter atp-binding protein
HV042_RS14730	COG1473	amidohydrolase
HV042_RS14735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV042_RS14760	COG4772	TonB-dependent receptor
HV042_RS14765	COG3691	Protein conserved in bacteria
HV042_RS14775	COG2130	NADP-dependent
HV042_RS14785	COG1247	-acetyltransferase
HV042_RS14790	COG3238	Protein conserved in bacteria
HV042_RS14800	COG0747	negative chemotaxis
HV042_RS14805	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS14810	COG4677	pectinesterase activity
HV042_RS14815	COG0596	Alpha beta hydrolase
HV042_RS14840	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS14845	COG1177	transmembrane transport
HV042_RS14850	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV042_RS14855	COG3842	ATPase activity
HV042_RS14860	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV042_RS14865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV042_RS14870	COG1271	oxidase subunit
HV042_RS14875	COG1294	oxidase, subunit
HV042_RS14890	COG0826	peptidase U32
HV042_RS14895	COG1396	sequence-specific DNA binding
HV042_RS14905	COG3135	benzoate transporter
HV042_RS14910	COG2207	Transcriptional regulator
HV042_RS14910	COG3708	Transcriptional regulator
HV042_RS14925	COG0747	negative chemotaxis
HV042_RS14930	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV042_RS14935	COG0500	methyltransferase
HV042_RS14940	COG1275	C4-dicarboxylate transporter malic acid transport protein
HV042_RS14945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV042_RS14950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV042_RS14960	COG1335	isochorismatase
HV042_RS14965	COG2272	Belongs to the type-B carboxylesterase lipase family
HV042_RS14970	COG5383	Protein conserved in bacteria
HV042_RS14975	COG3485	protocatechuate 3,4-dioxygenase
HV042_RS14980	COG3485	protocatechuate 3,4-dioxygenase
HV042_RS14985	COG0583	DNA-binding transcription factor activity
HV042_RS15010	COG3038	cytochrome b561
HV042_RS15035	COG3706	GGDEF domain
HV042_RS15040	COG0583	DNA-binding transcription factor activity
HV042_RS15045	COG0456	acetyltransferase
HV042_RS15050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HV042_RS15055	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS15060	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV042_RS15065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HV042_RS15090	COG4122	O-methyltransferase activity
HV042_RS15110	COG1643	Atp-dependent helicase
HV042_RS15125	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV042_RS15130	COG3327	negative regulation of DNA-templated transcription, initiation
HV042_RS15135	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HV042_RS15140	COG0183	Belongs to the thiolase family
HV042_RS15145	COG2050	protein possibly involved in aromatic compounds catabolism
HV042_RS15150	COG1250	3-hydroxyacyl-CoA dehydrogenase
HV042_RS15155	COG1024	Enoyl-CoA hydratase
HV042_RS15160	COG1024	Enoyl-CoA hydratase
HV042_RS15165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV042_RS15170	COG2151	metal-sulfur cluster biosynthetic enzyme
HV042_RS15175	COG3396	Phenylacetate-CoA oxygenase
HV042_RS15180	COG3460	Phenylacetate-CoA oxygenase
HV042_RS15185	COG3396	Phenylacetate-CoA oxygenase
HV042_RS15190	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS15190	COG2030	dehydratase
HV042_RS15205	COG3813	Protein conserved in bacteria
HV042_RS15210	COG0583	DNA-binding transcription factor activity
HV042_RS15225	COG1733	regulation of RNA biosynthetic process
HV042_RS15235	COG0406	alpha-ribazole phosphatase activity
HV042_RS15240	COG3547	Transposase (IS116 IS110 IS902 family)
HV042_RS15250	COG0583	DNA-binding transcription factor activity
HV042_RS15255	COG0583	DNA-binding transcription factor activity
HV042_RS15275	COG3039	Transposase
HV042_RS15280	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HV042_RS15285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV042_RS15290	COG4977	sequence-specific DNA binding
HV042_RS15300	COG0477	Major facilitator Superfamily
HV042_RS15320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV042_RS15325	COG2207	Transcriptional regulator
HV042_RS15325	COG3708	Transcriptional regulator
HV042_RS15330	COG2207	Transcriptional regulator
HV042_RS15345	COG1566	PFAM secretion protein HlyD family protein
HV042_RS15375	COG2072	flavoprotein involved in K transport
HV042_RS15380	COG0583	DNA-binding transcription factor activity
HV042_RS15385	COG1126	abc transporter atp-binding protein
HV042_RS15390	COG5285	phytanoyl-CoA dioxygenase
HV042_RS15405	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS15410	COG2207	Transcriptional regulator
HV042_RS15415	COG3784	Protein of unknown function (DUF1318)
HV042_RS15425	COG2911	Protein conserved in bacteria
HV042_RS15435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HV042_RS15440	COG3187	Heat shock protein
HV042_RS15445	COG3042	response to heat
HV042_RS15490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV042_RS15490	COG1013	pyruvate-flavodoxin oxidoreductase activity
HV042_RS15490	COG0674	pyruvate-flavodoxin oxidoreductase activity
HV042_RS15490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HV042_RS15495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV042_RS15515	COG0513	Belongs to the DEAD box helicase family
HV042_RS15575	COG1802	Transcriptional regulator
HV042_RS15575	COG4626	Terminase
HV042_RS15655	COG0582	viral genome integration into host DNA
HV042_RS15665	COG1349	DNA-binding transcription factor activity
HV042_RS15670	COG0673	inositol 2-dehydrogenase activity
HV042_RS15675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HV042_RS15700	COG3477	response to acidic pH
HV042_RS15705	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HV042_RS15705	COG2885	chlorophyll binding
HV042_RS15720	COG0583	DNA-binding transcription factor activity
HV042_RS15735	COG0583	DNA-binding transcription factor activity
HV042_RS15760	COG0789	Transcriptional regulator
HV042_RS15770	COG0300	oxidoreductase activity
HV042_RS15785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV042_RS15805	COG3272	Protein of unknown function (DUF1722)
HV042_RS15810	COG4580	involved in the transport of maltose and maltodextrins
HV042_RS15820	COG2211	Major facilitator Superfamily
HV042_RS15825	COG3507	Belongs to the glycosyl hydrolase 43 family
HV042_RS15840	COG0693	protein deglycase activity
HV042_RS15845	COG4166	transmembrane transport
HV042_RS15850	COG2866	Carboxypeptidase
HV042_RS15855	COG4948	Mandelate Racemase Muconate Lactonizing
HV042_RS15860	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HV042_RS15865	COG3180	Ammonia monooxygenase
HV042_RS15880	COG3106	COG3106 Predicted ATPase
HV042_RS15885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV042_RS15895	COG1983	PspC domain protein
HV042_RS15905	COG1842	Phage shock protein A
HV042_RS15910	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV042_RS15920	COG1473	amidohydrolase
HV042_RS15935	COG4166	transmembrane transport
HV042_RS15945	COG4171	peptide transport system, permease
HV042_RS15955	COG4172	Belongs to the ABC transporter superfamily
HV042_RS15965	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HV042_RS15970	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV042_RS15970	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV042_RS15985	COG1349	DNA-binding transcription factor activity
HV042_RS15995	COG0023	Translation Initiation Factor
HV042_RS16005	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HV042_RS16010	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HV042_RS16015	COG0671	phosphoesterase, PA-phosphatase related
HV042_RS16025	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HV042_RS16050	COG0616	signal peptide processing
HV042_RS16055	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS16060	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HV042_RS16070	COG1472	Belongs to the glycosyl hydrolase 3 family
HV042_RS16075	COG2211	Major facilitator Superfamily
HV042_RS16080	COG1187	pseudouridine synthase activity
HV042_RS16095	COG4907	membrane protein (DUF2207)
HV042_RS16100	COG0009	L-threonylcarbamoyladenylate synthase
HV042_RS16110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HV042_RS16115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV042_RS16115	COG0512	Glutamine amidotransferase of anthranilate synthase
HV042_RS16120	COG0134	indole-3-glycerol-phosphate synthase activity
HV042_RS16120	COG0135	phosphoribosylanthranilate isomerase activity
HV042_RS16140	COG1063	alcohol dehydrogenase
HV042_RS16165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV042_RS16250	COG4386	tail sheath protein
HV042_RS16330	COG3039	Transposase
HV042_RS16340	COG3179	chitinase
HV042_RS16360	COG1403	HNH endonuclease
HV042_RS16365	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HV042_RS16430	COG1396	sequence-specific DNA binding
HV042_RS16450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV042_RS16460	COG0582	viral genome integration into host DNA
HV042_RS16465	COG3047	cAMP biosynthetic process
HV042_RS16495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV042_RS16500	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS16505	COG1988	membrane-bound metal-dependent
HV042_RS16520	COG0753	catalase activity
HV042_RS16530	COG1486	melibiose metabolic process
HV042_RS16540	COG3039	Transposase
HV042_RS16550	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV042_RS16560	COG0322	excinuclease ABC activity
HV042_RS16565	COG4907	membrane protein (DUF2207)
HV042_RS16570	COG1704	LemA family
HV042_RS16575	COG3678	ATP-independent chaperone mediated protein folding
HV042_RS16595	COG3138	arginine N-succinyltransferase
HV042_RS16605	COG0708	Exodeoxyribonuclease III
HV042_RS16610	COG0398	Pfam SNARE associated Golgi protein
HV042_RS16615	COG0398	Pfam SNARE associated Golgi protein
HV042_RS16620	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV042_RS16625	COG4134	Bacterial extracellular solute-binding protein
HV042_RS16630	COG4135	transport system, permease component
HV042_RS16635	COG4136	ATPase activity
HV042_RS16640	COG2897	thiosulfate sulfurtransferase activity
HV042_RS16645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HV042_RS16650	COG0494	nUDIX hydrolase
HV042_RS16660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HV042_RS16665	COG0709	Synthesizes selenophosphate from selenide and ATP
HV042_RS16675	COG0778	Nitroreductase
HV042_RS16680	COG0616	signal peptide processing
HV042_RS16685	COG0252	asparaginase activity
HV042_RS16690	COG1335	isochorismatase
HV042_RS16695	COG2814	Major facilitator Superfamily
HV042_RS16700	COG1349	DNA-binding transcription factor activity
HV042_RS16705	COG0667	Aldo Keto reductase
HV042_RS16710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV042_RS16715	COG0191	fructose-bisphosphate aldolase activity
HV042_RS16720	COG1063	alcohol dehydrogenase
HV042_RS16725	COG2271	Major facilitator Superfamily
HV042_RS16730	COG1063	alcohol dehydrogenase
HV042_RS16745	COG3139	Protein of unknown function (DUF1315)
HV042_RS16765	COG0656	L-ascorbic acid biosynthetic process
HV042_RS16770	COG3713	MltA-interacting MipA family protein
HV042_RS16775	COG2766	serine protein kinase
HV042_RS16785	COG0859	PFAM glycosyl transferase family 9
HV042_RS16790	COG2199	diguanylate cyclase activity
HV042_RS16795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV042_RS16805	COG2207	Transcriptional regulator
HV042_RS16810	COG2807	transmembrane transport
HV042_RS16815	COG0504	CTP synthase activity
HV042_RS16820	COG1683	Conserved Protein
HV042_RS16825	COG3189	MarR family transcriptional regulator
HV042_RS16830	COG3042	response to heat
HV042_RS16965	COG4695	Portal protein
HV042_RS17035	COG4974	Belongs to the 'phage' integrase family
HV042_RS17040	COG2203	Gaf domain
HV042_RS17040	COG2199	diguanylate cyclase activity
HV042_RS17060	COG3182	Iron-regulated membrane protein
HV042_RS17070	COG1560	Kdo2-lipid A biosynthetic process
HV042_RS17075	COG1595	DNA-templated transcription, initiation
HV042_RS17080	COG3712	iron ion homeostasis
HV042_RS17085	COG4772	TonB-dependent receptor
HV042_RS17090	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HV042_RS17095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV042_RS17100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV042_RS17105	COG1120	ATPase activity
HV042_RS17115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HV042_RS17120	COG3706	GGDEF domain
HV042_RS17125	COG0583	DNA-binding transcription factor activity
HV042_RS17140	COG0538	isocitrate dehydrogenase activity
HV042_RS17145	COG1187	pseudouridine synthase activity
HV042_RS17165	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HV042_RS17180	COG2814	Major facilitator Superfamily
HV042_RS17190	COG0745	RESPONSE REGULATOR receiver
HV042_RS17195	COG2205	protein histidine kinase activity
HV042_RS17200	COG2850	peptidyl-arginine hydroxylation
HV042_RS17220	COG1177	transmembrane transport
HV042_RS17235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HV042_RS17245	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV042_RS17250	COG1136	(ABC) transporter
HV042_RS17255	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV042_RS17260	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HV042_RS17265	COG1388	LysM domain
HV042_RS17265	COG1376	ErfK ybiS ycfS ynhG family protein
HV042_RS17280	COG1309	transcriptional regulator
HV042_RS17290	COG3134	Outer membrane lipoprotein
HV042_RS17295	COG1252	NADH dehydrogenase
HV042_RS17320	COG5633	Lipoprotein
HV042_RS17325	COG0537	adenosine 5'-monophosphoramidase activity
HV042_RS17330	COG4773	Receptor
HV042_RS17335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV042_RS17335	COG1263	PTS System
HV042_RS17340	COG0084	hydrolase, TatD family'
HV042_RS17345	COG0470	DNA polymerase III
HV042_RS17355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HV042_RS17360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV042_RS17365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV042_RS17380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HV042_RS17400	COG1399	metal-binding, possibly nucleic acid-binding protein
HV042_RS17405	COG0424	maF-like protein
HV042_RS17420	COG1530	ribonuclease E activity
HV042_RS17425	COG0583	DNA-binding transcription factor activity
HV042_RS17430	COG2814	Major facilitator Superfamily
HV042_RS17440	COG0673	inositol 2-dehydrogenase activity
HV042_RS17450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV042_RS17460	COG2999	glutathione oxidoreductase activity
HV042_RS17480	COG3039	Transposase
HV042_RS17505	COG1560	Kdo2-lipid A biosynthetic process
HV042_RS17520	COG5645	(Lipo)protein
HV042_RS17560	COG3381	protein complex oligomerization
HV042_RS17580	COG0583	DNA-binding transcription factor activity
HV042_RS17590	COG1335	isochorismatase
HV042_RS17610	COG5002	protein histidine kinase activity
HV042_RS17610	COG3850	Histidine kinase
HV042_RS17630	COG1702	phosphate starvation-inducible protein PhoH
HV042_RS17635	COG2837	iron assimilation
HV042_RS17640	COG2822	iron ion transport
HV042_RS17650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV042_RS17660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV042_RS17675	COG1309	transcriptional regulator
HV042_RS17710	COG2233	PERMEase
HV042_RS17715	COG3729	General stress protein
HV042_RS17745	COG0531	amino acid
HV042_RS17750	COG0174	glutamine synthetase
HV042_RS17755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HV042_RS17760	COG1917	Cupin 2, conserved barrel domain protein
HV042_RS17760	COG1396	sequence-specific DNA binding
HV042_RS17765	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS17770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HV042_RS17775	COG0583	DNA-binding transcription factor activity
HV042_RS17780	COG0473	3-isopropylmalate dehydrogenase activity
HV042_RS17785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS17785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS17785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV042_RS17790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV042_RS17795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV042_RS17800	COG1882	Formate acetyltransferase
HV042_RS17805	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV042_RS17810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV042_RS17820	COG2207	Transcriptional regulator
HV042_RS17825	COG3706	GGDEF domain
HV042_RS17845	COG1605	Chorismate mutase
HV042_RS17845	COG0287	Prephenate dehydrogenase
HV042_RS17855	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HV042_RS17870	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HV042_RS17935	COG1953	Uracil, thiamine, allantoin
HV042_RS17940	COG0402	S-adenosylhomocysteine deaminase activity
HV042_RS17945	COG2351	hydroxyisourate hydrolase activity
HV042_RS17955	COG2233	PERMEase
HV042_RS17960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV042_RS18020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HV042_RS18030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV042_RS18040	COG1278	Cold shock
HV042_RS18045	COG1278	Cold shock
HV042_RS18065	COG0765	amino acid transport
HV042_RS18080	COG1309	transcriptional regulator
HV042_RS18120	COG1486	melibiose metabolic process
HV042_RS18125	COG2223	nitrite transmembrane transporter activity
HV042_RS18130	COG2207	Transcriptional regulator
HV042_RS18140	COG0477	Major facilitator Superfamily
HV042_RS18155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV042_RS18165	COG1126	abc transporter atp-binding protein
HV042_RS18170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV042_RS18180	COG0006	proline dipeptidase activity
HV042_RS18185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV042_RS18195	COG0436	Aminotransferase
HV042_RS18200	COG2188	Transcriptional regulator
HV042_RS18210	COG3715	PTS system
HV042_RS18215	COG3716	PTS system mannose fructose sorbose family IID component
HV042_RS18220	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV042_RS18225	COG4821	SIS domain
HV042_RS18235	COG4821	SIS domain
HV042_RS18320	COG1196	nuclear chromosome segregation
HV042_RS18370	COG0616	signal peptide processing
HV042_RS18390	COG4220	transposase activity
HV042_RS18435	COG1403	HNH endonuclease
HV042_RS18440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HV042_RS18490	COG1484	DNA-dependent DNA replication
HV042_RS18495	COG3756	Protein conserved in bacteria
HV042_RS18530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV042_RS18555	COG0670	Belongs to the BI1 family
HV042_RS18570	COG2207	Transcriptional regulator
HV042_RS18575	COG1881	PFAM PEBP family protein
HV042_RS18595	COG0438	transferase activity, transferring glycosyl groups
HV042_RS18600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV042_RS18605	COG2274	protein secretion by the type I secretion system
HV042_RS18630	COG1832	CoA-binding protein
HV042_RS18640	COG0210	DNA helicase
HV042_RS18645	COG3304	Inner membrane component domain
HV042_RS18650	COG1289	transmembrane transporter activity
HV042_RS18655	COG3070	regulator of competence-specific genes
HV042_RS18675	COG1067	ATP-dependent peptidase activity
HV042_RS18685	COG3130	regulation of translation
HV042_RS18690	COG3009	Protein conserved in bacteria
HV042_RS18695	COG3008	intermembrane lipid transfer
HV042_RS18695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV042_RS18700	COG2995	paraquat-inducible protein a
HV042_RS18705	COG0488	(ABC) transporter
HV042_RS18715	COG0633	Ferredoxin
HV042_RS18715	COG3217	Mosc domain protein beta barrel domain protein
HV042_RS18730	COG0431	NADPH-dependent FMN reductase
HV042_RS18735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV042_RS18745	COG0308	aminopeptidase N
HV042_RS18760	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV042_RS18765	COG1448	Aminotransferase
HV042_RS18770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV042_RS18775	COG3108	Peptidase M15
HV042_RS18780	COG2989	Protein conserved in bacteria
HV042_RS18790	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HV042_RS18800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HV042_RS18805	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV042_RS18810	COG3173	Aminoglycoside phosphotransferase
HV042_RS18825	COG3214	Protein conserved in bacteria
HV042_RS18835	COG1132	(ABC) transporter
HV042_RS18840	COG0658	competence protein
HV042_RS18840	COG2333	competence protein COMEC
HV042_RS18850	COG0539	negative regulation of cytoplasmic translation
HV042_RS18860	COG0501	Belongs to the peptidase M48B family
HV042_RS18875	COG2323	membrane
HV042_RS18880	COG1944	ATP diphosphatase activity
HV042_RS18885	COG2116	formate transmembrane transporter activity
HV042_RS18890	COG1882	Formate acetyltransferase
HV042_RS18895	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV042_RS18900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HV042_RS18915	COG3959	Transketolase, thiamine diphosphate binding domain
HV042_RS18920	COG3958	Transketolase
HV042_RS18925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS18930	COG0477	Major facilitator Superfamily
HV042_RS18935	COG3302	dmso reductase anchor subunit
HV042_RS18940	COG0437	4 iron, 4 sulfur cluster binding
HV042_RS18945	COG0243	molybdopterin cofactor binding
HV042_RS18955	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HV042_RS18965	COG1674	ftsk spoiiie
HV042_RS18965	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV042_RS18975	COG0492	ferredoxin-NADP+ reductase activity
HV042_RS18980	COG4988	ABC transporter
HV042_RS18985	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HV042_RS18995	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HV042_RS19000	COG0542	response to heat
HV042_RS19005	COG3039	Transposase
HV042_RS19015	COG1278	Cold shock
HV042_RS19025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV042_RS19030	COG3593	DNA synthesis involved in DNA repair
HV042_RS19035	COG3039	Transposase
HV042_RS19040	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HV042_RS19045	COG2431	L-lysine efflux transmembrane transporter activity
HV042_RS19055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV042_RS19065	COG0028	Belongs to the TPP enzyme family
HV042_RS19070	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HV042_RS19075	COG0702	epimerase
HV042_RS19080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV042_RS19085	COG3023	N-Acetylmuramoyl-L-alanine amidase
HV042_RS19090	COG0393	Putative heavy-metal-binding
HV042_RS19100	COG1126	abc transporter atp-binding protein
HV042_RS19105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV042_RS19110	COG4215	(ABC) transporter
HV042_RS19115	COG4160	amino acid transport
HV042_RS19120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV042_RS19130	COG0745	RESPONSE REGULATOR receiver
HV042_RS19145	COG1177	transmembrane transport
HV042_RS19150	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV042_RS19155	COG3842	ATPase activity
HV042_RS19160	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV042_RS19175	COG0778	Nitroreductase
HV042_RS19200	COG3226	Transcriptional regulator
HV042_RS19205	COG0738	Major facilitator superfamily
HV042_RS19210	COG0561	phosphatase activity
HV042_RS19215	COG2814	Major facilitator Superfamily
HV042_RS19220	COG0671	phosphoesterase, PA-phosphatase related
HV042_RS19225	COG1349	DNA-binding transcription factor activity
HV042_RS19230	COG1686	Belongs to the peptidase S11 family
HV042_RS19235	COG0625	glutathione transferase activity
HV042_RS19240	COG2133	pyrroloquinoline quinone binding
HV042_RS19250	COG2223	nitrite transmembrane transporter activity
HV042_RS19275	COG0747	negative chemotaxis
HV042_RS19285	COG1446	asparaginase
HV042_RS19290	COG0303	'Molybdopterin
HV042_RS19295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV042_RS19300	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV042_RS19305	COG1882	Formate acetyltransferase
HV042_RS19310	COG0561	phosphatase activity
HV042_RS19320	COG1609	Transcriptional regulator
HV042_RS19325	COG2271	Major facilitator Superfamily
HV042_RS19335	COG0488	(ABC) transporter
HV042_RS19345	COG1376	ErfK ybiS ycfS ynhG family protein
HV042_RS19350	COG2188	Transcriptional regulator
HV042_RS19355	COG2723	6-phospho-beta-galactosidase activity
HV042_RS19360	COG0667	Aldo Keto reductase
HV042_RS19365	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV042_RS19380	COG2194	sulfuric ester hydrolase activity
HV042_RS19385	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HV042_RS19400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV042_RS19405	COG0765	amino acid transport
HV042_RS19410	COG1126	abc transporter atp-binding protein
HV042_RS19415	COG0668	transmembrane transport
HV042_RS19430	COG4774	siderophore transport
HV042_RS19440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV042_RS19450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV042_RS19460	COG0513	Belongs to the DEAD box helicase family
HV042_RS19465	COG3958	Transketolase
HV042_RS19470	COG3959	Transketolase, thiamine diphosphate binding domain
HV042_RS19475	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS19480	COG2271	Major facilitator Superfamily
HV042_RS19485	COG0583	DNA-binding transcription factor activity
HV042_RS19490	COG1309	transcriptional regulator
HV042_RS19500	COG1131	(ABC) transporter
HV042_RS19505	COG0842	Transport permease protein
HV042_RS19510	COG0842	Transport permease protein
HV042_RS19520	COG3568	Endonuclease Exonuclease Phosphatase
HV042_RS19525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV042_RS19530	COG0392	lysyltransferase activity
HV042_RS19535	COG0670	Belongs to the BI1 family
HV042_RS19540	COG0314	molybdopterin synthase activity
HV042_RS19545	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HV042_RS19555	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV042_RS19575	COG0745	RESPONSE REGULATOR receiver
HV042_RS19600	COG2226	methyltransferase
HV042_RS19615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HV042_RS19620	COG1881	PFAM PEBP family protein
HV042_RS19660	COG4677	pectinesterase activity
HV042_RS19675	COG0789	Transcriptional regulator
HV042_RS19680	COG2200	EAL domain
HV042_RS19700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV042_RS19715	COG0561	phosphatase activity
HV042_RS19725	COG4149	molybdate abc transporter
HV042_RS19730	COG0725	ABC transporter, periplasmic molybdate-binding protein
HV042_RS19740	COG3585	molybdate ion transport
HV042_RS19740	COG2005	Transcriptional regulator
HV042_RS19745	COG1119	ATPase activity
HV042_RS19750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HV042_RS19755	COG1085	galactose-1-phosphate uridylyltransferase
HV042_RS19765	COG2017	converts alpha-aldose to the beta-anomer
HV042_RS19775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV042_RS19790	COG3201	nicotinamide mononucleotide transporter
HV042_RS19795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HV042_RS19830	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HV042_RS19835	COG2885	chlorophyll binding
HV042_RS19845	COG3064	Membrane
HV042_RS19845	COG3064	Membrane
HV042_RS19850	COG0848	biopolymer transport protein
HV042_RS19855	COG0811	peptide transport
HV042_RS19860	COG0824	Thioesterase
HV042_RS19865	COG3790	cyd operon protein YbgE
HV042_RS19870	COG4890	Cyd operon protein YbgT
HV042_RS19875	COG1294	oxidase, subunit
HV042_RS19880	COG1271	oxidase subunit
HV042_RS19885	COG3039	Transposase
HV042_RS19890	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV042_RS19900	COG4865	methylaspartate mutase activity
HV042_RS19905	COG3799	methylaspartate ammonia-lyase activity
HV042_RS19920	COG1301	dicarboxylic acid transport
HV042_RS19930	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV042_RS19930	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV042_RS19940	COG0583	DNA-binding transcription factor activity
HV042_RS19950	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV042_RS19960	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV042_RS19965	COG0567	Dehydrogenase, E1 component
HV042_RS19970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV042_RS19975	COG1053	succinate dehydrogenase
HV042_RS19980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HV042_RS19990	COG0372	Belongs to the citrate synthase family
HV042_RS20020	COG1984	allophanate hydrolase subunit 2
HV042_RS20025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HV042_RS20030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HV042_RS20040	COG0415	Belongs to the DNA photolyase family
HV042_RS20070	COG2205	protein histidine kinase activity
HV042_RS20075	COG0745	RESPONSE REGULATOR receiver
HV042_RS20080	COG0235	Class ii aldolase
HV042_RS20085	COG3623	hexulose-6-phosphate isomerase
HV042_RS20090	COG1070	Carbohydrate kinase
HV042_RS20095	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS20100	COG1129	ABC transporter
HV042_RS20105	COG1879	ABC-type sugar transport system periplasmic component
HV042_RS20110	COG1063	alcohol dehydrogenase
HV042_RS20115	COG1349	DNA-binding transcription factor activity
HV042_RS20125	COG0033	Phosphoglucomutase
HV042_RS20135	COG0596	Alpha beta hydrolase
HV042_RS20150	COG0735	belongs to the Fur family
HV042_RS20155	COG0583	DNA-binding transcription factor activity
HV042_RS20160	COG1053	succinate dehydrogenase
HV042_RS20200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV042_RS20205	COG1846	Transcriptional regulator
HV042_RS20205	COG1940	carbohydrate kinase activity
HV042_RS20210	COG0647	UMP catabolic process
HV042_RS20215	COG3039	Transposase
HV042_RS20235	COG0367	asparagine synthase
HV042_RS20275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV042_RS20285	COG1702	phosphate starvation-inducible protein PhoH
HV042_RS20290	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HV042_RS20295	COG4535	Mg2 and Co2 transporter CorC
HV042_RS20310	COG0765	amino acid transport
HV042_RS20315	COG0765	amino acid transport
HV042_RS20320	COG1126	abc transporter atp-binding protein
HV042_RS20330	COG3210	domain, Protein
HV042_RS20335	COG2888	peptidyl-tyrosine sulfation
HV042_RS20350	COG1466	dna polymerase III delta subunit
HV042_RS20365	COG0799	negative regulation of ribosome biogenesis
HV042_RS20375	COG0768	penicillin binding
HV042_RS20380	COG0772	Belongs to the SEDS family
HV042_RS20385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV042_RS20390	COG1686	Belongs to the peptidase S11 family
HV042_RS20405	COG0583	DNA-binding transcription factor activity
HV042_RS20415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HV042_RS20420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV042_RS20440	COG3069	C4-dicarboxylate transmembrane transporter activity
HV042_RS20445	COG3719	Belongs to the RNase T2 family
HV042_RS20450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV042_RS20460	COG3634	alkyl hydroperoxide reductase activity
HV042_RS20470	COG0583	DNA-binding transcription factor activity
HV042_RS20475	COG3969	phosphoadenosine phosphosulfate
HV042_RS20480	COG1475	DNA binding
HV042_RS20485	COG0436	Aminotransferase
HV042_RS20490	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
HV042_RS20495	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HV042_RS20510	COG1129	ABC transporter
HV042_RS20515	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS20520	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS20530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV042_RS20550	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HV042_RS20560	COG0402	S-adenosylhomocysteine deaminase activity
HV042_RS20570	COG0483	inositol monophosphate 1-phosphatase activity
HV042_RS20575	COG2271	Major facilitator Superfamily
HV042_RS20605	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS20610	COG1129	ABC transporter
HV042_RS20615	COG0371	Dehydrogenase
HV042_RS20630	COG2879	small protein
HV042_RS20635	COG1966	Carbon starvation protein
HV042_RS20645	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS20650	COG3433	isochorismatase activity
HV042_RS20650	COG1535	isochorismatase
HV042_RS20655	COG1021	2,3-dihydroxybenzoate-AMP ligase
HV042_RS20660	COG1169	isochorismate synthase
HV042_RS20665	COG4592	Periplasmic binding protein
HV042_RS20675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV042_RS20680	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV042_RS20685	COG1120	ATPase activity
HV042_RS20690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HV042_RS20690	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HV042_RS20695	COG3251	PFAM MbtH domain protein
HV042_RS20700	COG2382	esterase
HV042_RS20705	COG4771	TonB-dependent receptor
HV042_RS20710	COG2977	Belongs to the P-Pant transferase superfamily
HV042_RS20715	COG3958	Transketolase
HV042_RS20720	COG3959	Transketolase, thiamine diphosphate binding domain
HV042_RS20725	COG2390	Transcriptional regulator
HV042_RS20730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HV042_RS20735	COG1879	ABC-type sugar transport system periplasmic component
HV042_RS20745	COG1129	ABC transporter
HV042_RS20750	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS20760	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS20770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HV042_RS20800	COG4221	oxidoreductase activity
HV042_RS20810	COG0765	amino acid transport
HV042_RS20815	COG0765	amino acid transport
HV042_RS20830	COG1280	lysine exporter protein (LysE YggA)
HV042_RS20840	COG0697	spore germination
HV042_RS20850	COG0154	amidase activity
HV042_RS20855	COG0444	Belongs to the ABC transporter superfamily
HV042_RS20860	COG4608	Belongs to the ABC transporter superfamily
HV042_RS20865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV042_RS20875	COG4166	transmembrane transport
HV042_RS20885	COG3698	Phosphodiester glycosidase
HV042_RS20915	COG4774	siderophore transport
HV042_RS20935	COG2315	Protein conserved in bacteria
HV042_RS20940	COG0778	Nitroreductase
HV042_RS20950	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV042_RS20955	COG3715	PTS system
HV042_RS20960	COG3716	PTS system mannose fructose sorbose family IID component
HV042_RS20970	COG2222	sugar isomerase
HV042_RS20975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV042_RS20975	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HV042_RS20990	COG0477	Major facilitator Superfamily
HV042_RS20995	COG0668	transmembrane transport
HV042_RS21000	COG1609	Transcriptional regulator
HV042_RS21005	COG0494	nUDIX hydrolase
HV042_RS21045	COG0583	DNA-binding transcription factor activity
HV042_RS21050	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS21065	COG1082	Xylose isomerase domain protein TIM barrel
HV042_RS21070	COG2211	Major facilitator Superfamily
HV042_RS21075	COG1113	amino acid transport
HV042_RS21085	COG0667	Aldo Keto reductase
HV042_RS21090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV042_RS21095	COG1473	amidohydrolase
HV042_RS21135	COG3550	peptidyl-serine autophosphorylation
HV042_RS21145	COG3711	transcriptional antiterminator
HV042_RS21150	COG2723	6-phospho-beta-galactosidase activity
HV042_RS21155	COG2190	(PTS) system
HV042_RS21155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV042_RS21155	COG1263	PTS System
HV042_RS21160	COG0583	DNA-binding transcription factor activity
HV042_RS21200	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS21205	COG1129	ABC transporter
HV042_RS21220	COG0673	inositol 2-dehydrogenase activity
HV042_RS21230	COG2367	Beta-lactamase
HV042_RS21245	COG3104	oligopeptide transport
HV042_RS21250	COG1982	Orn Lys Arg decarboxylase major
HV042_RS21255	COG0531	amino acid
HV042_RS21260	COG3710	Transcriptional regulator
HV042_RS21280	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HV042_RS21300	COG1285	pathogenesis
HV042_RS21305	COG2211	Major facilitator Superfamily
HV042_RS21375	COG0582	viral genome integration into host DNA
HV042_RS21490	COG0582	viral genome integration into host DNA
HV042_RS21505	COG2501	S4 domain
HV042_RS21515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HV042_RS21530	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HV042_RS21535	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HV042_RS21540	COG0549	Belongs to the carbamate kinase family
HV042_RS21550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV042_RS21555	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV042_RS21560	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV042_RS21565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV042_RS21570	COG3257	ureidoglycine aminohydrolase activity
HV042_RS21575	COG1929	Belongs to the glycerate kinase type-1 family
HV042_RS21580	COG2233	PERMEase
HV042_RS21590	COG1953	Uracil, thiamine, allantoin
HV042_RS21600	COG2084	Dehydrogenase
HV042_RS21605	COG3622	Belongs to the hyi family
HV042_RS21610	COG3960	tartronate-semialdehyde synthase activity
HV042_RS21645	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HV042_RS21650	COG4181	ATPase activity
HV042_RS21655	COG2755	lipolytic protein G-D-S-L family
HV042_RS21660	COG0300	oxidoreductase activity
HV042_RS21665	COG3118	belongs to the thioredoxin family
HV042_RS21670	COG0390	transport system, permease component
HV042_RS21675	COG4619	ABC transporter
HV042_RS21680	COG0330	HflC and HflK could
HV042_RS21685	COG1585	Membrane protein implicated in regulation of membrane protease activity
HV042_RS21705	COG0811	peptide transport
HV042_RS21725	COG3735	TraB family
HV042_RS21730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV042_RS21740	COG2223	nitrite transmembrane transporter activity
HV042_RS21745	COG4651	solute:proton antiporter activity
HV042_RS21745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HV042_RS21750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV042_RS21780	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HV042_RS21790	COG2832	Protein of unknown function (DUF454)
HV042_RS21795	COG3923	Primosomal replication protein n
HV042_RS21810	COG3264	Mechanosensitive ion channel
HV042_RS21810	COG1196	nuclear chromosome segregation
HV042_RS21815	COG1309	transcriptional regulator
HV042_RS21820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV042_RS21825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV042_RS21840	COG0110	maltose O-acetyltransferase activity
HV042_RS21860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HV042_RS21880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV042_RS21880	COG1263	PTS System
HV042_RS21885	COG1874	Beta-galactosidase
HV042_RS21890	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HV042_RS21895	COG3833	ABC-type maltose transport systems, permease component
HV042_RS21900	COG1175	transmembrane transport
HV042_RS21905	COG2182	Extracellular solute-binding protein
HV042_RS21915	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV042_RS21930	COG5507	3-demethylubiquinone-9 3-methyltransferase
HV042_RS21935	COG2364	Membrane
HV042_RS21965	COG3695	enzyme binding
HV042_RS21970	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HV042_RS21975	COG1946	Acyl-CoA thioesterase
HV042_RS21980	COG0583	DNA-binding transcription factor activity
HV042_RS21985	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV042_RS21990	COG1811	Na channel or pump
HV042_RS21995	COG0004	ammonium transporteR
HV042_RS22000	COG0347	Belongs to the P(II) protein family
HV042_RS22005	COG1132	(ABC) transporter
HV042_RS22010	COG1132	(ABC) transporter
HV042_RS22015	COG1522	sequence-specific DNA binding
HV042_RS22030	COG4533	DNA binding
HV042_RS22040	COG0824	Thioesterase
HV042_RS22045	COG1555	photosystem II stabilization
HV042_RS22050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV042_RS22055	COG0776	regulation of translation
HV042_RS22060	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HV042_RS22080	COG0271	Belongs to the BolA IbaG family
HV042_RS22085	COG3056	Lipoprotein
HV042_RS22090	COG2223	nitrite transmembrane transporter activity
HV042_RS22095	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HV042_RS22100	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HV042_RS22105	COG1845	cytochrome c oxidase, subunit III
HV042_RS22110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HV042_RS22125	COG1414	Transcriptional regulator
HV042_RS22160	COG2211	Major facilitator Superfamily
HV042_RS22165	COG0673	inositol 2-dehydrogenase activity
HV042_RS22170	COG2814	Major facilitator Superfamily
HV042_RS22180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HV042_RS22200	COG0142	geranyltranstransferase activity
HV042_RS22210	COG0667	Aldo Keto reductase
HV042_RS22215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HV042_RS22220	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HV042_RS22235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV042_RS22235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV042_RS22245	COG4238	major outer membrane lipoprotein
HV042_RS22270	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV042_RS22275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV042_RS22280	COG1862	Preprotein translocase
HV042_RS22295	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HV042_RS22300	COG0450	alkyl hydroperoxide reductase
HV042_RS22315	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HV042_RS22325	COG1335	isochorismatase
HV042_RS22330	COG0583	DNA-binding transcription factor activity
HV042_RS22335	COG0366	Alpha amylase catalytic
HV042_RS22360	COG0420	3'-5' exonuclease activity
HV042_RS22365	COG0419	ATPase involved in DNA repair
HV042_RS22375	COG1940	carbohydrate kinase activity
HV042_RS22390	COG4126	flavin adenine dinucleotide binding
HV042_RS22400	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HV042_RS22405	COG3416	Protein conserved in bacteria
HV042_RS22415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HV042_RS22425	COG1785	Belongs to the alkaline phosphatase family
HV042_RS22435	COG1609	Transcriptional regulator
HV042_RS22445	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS22480	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HV042_RS22490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HV042_RS22495	COG0113	porphobilinogen synthase activity
HV042_RS22510	COG2175	clavaminate synthase activity
HV042_RS22515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV042_RS22520	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HV042_RS22525	COG4521	taurine ABC transporter
HV042_RS22540	COG2271	Major facilitator Superfamily
HV042_RS22545	COG1840	ABC-type Fe3 transport system, periplasmic component
HV042_RS22555	COG3842	ATPase activity
HV042_RS22560	COG2040	homocysteine
HV042_RS22565	COG0833	amino acid
HV042_RS22570	COG5434	Belongs to the glycosyl hydrolase 28 family
HV042_RS22575	COG0531	amino acid
HV042_RS22580	COG4303	Ethanolamine ammonia lyase large subunit
HV042_RS22585	COG4302	ethanolamine ammonia-lyase activity
HV042_RS22625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV042_RS22630	COG1126	abc transporter atp-binding protein
HV042_RS22635	COG0765	amino acid transport
HV042_RS22640	COG0765	amino acid transport
HV042_RS22655	COG3188	usher protein
HV042_RS22680	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HV042_RS22690	COG3639	organic phosphonate transmembrane transporter activity
HV042_RS22710	COG3118	belongs to the thioredoxin family
HV042_RS22720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV042_RS22730	COG0583	DNA-binding transcription factor activity
HV042_RS22735	COG0791	NLP P60 protein
HV042_RS22740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV042_RS22745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HV042_RS22750	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HV042_RS22770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV042_RS22780	COG1733	regulation of RNA biosynthetic process
HV042_RS22790	COG2085	NADP oxidoreductase coenzyme F420-dependent
HV042_RS22795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV042_RS22815	COG1309	transcriptional regulator
HV042_RS22830	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV042_RS22840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV042_RS22850	COG0477	Major facilitator Superfamily
HV042_RS22860	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HV042_RS22865	COG3153	acetyltransferase
HV042_RS22880	COG0246	Mannitol dehydrogenase
HV042_RS22885	COG2186	Transcriptional regulator
HV042_RS22905	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS22910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HV042_RS22920	COG1596	polysaccharide export
HV042_RS22940	COG0463	Glycosyl transferase, family 2
HV042_RS22945	COG0438	transferase activity, transferring glycosyl groups
HV042_RS22950	COG0297	glycogen (starch) synthase activity
HV042_RS22950	COG0438	transferase activity, transferring glycosyl groups
HV042_RS22965	COG1045	serine acetyltransferase
HV042_RS22985	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV042_RS22990	COG0454	-acetyltransferase
HV042_RS23005	COG2991	Protein conserved in bacteria
HV042_RS23020	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV042_RS23025	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV042_RS23040	COG3034	peptidoglycan biosynthetic process
HV042_RS23045	COG0121	glutamine amidotransferase
HV042_RS23055	COG1960	acyl-CoA dehydrogenase activity
HV042_RS23060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV042_RS23080	COG2226	methyltransferase
HV042_RS23090	COG1388	LysM domain
HV042_RS23090	COG0741	lytic transglycosylase activity
HV042_RS23095	COG2226	methyltransferase
HV042_RS23105	COG2814	Major facilitator Superfamily
HV042_RS23110	COG0583	DNA-binding transcription factor activity
HV042_RS23115	COG0656	L-ascorbic acid biosynthetic process
HV042_RS23150	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HV042_RS23160	COG2011	ABC-type metal ion transport system permease component
HV042_RS23165	COG1464	Belongs to the NlpA lipoprotein family
HV042_RS23175	COG1720	tRNA m6t6A37 methyltransferase activity
HV042_RS23185	COG3015	lipoprotein NlpE involved in copper resistance
HV042_RS23190	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HV042_RS23195	COG4681	YaeQ
HV042_RS23205	COG4568	rho-dependent transcription termination
HV042_RS23215	COG0346	lactoylglutathione lyase activity
HV042_RS23250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HV042_RS23255	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HV042_RS23260	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HV042_RS23270	COG0750	zinc metalloprotease
HV042_RS23275	COG0575	Belongs to the CDS family
HV042_RS23285	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HV042_RS23300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HV042_RS23310	COG0024	Methionine aminopeptidase
HV042_RS23315	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HV042_RS23330	COG3835	regulator
HV042_RS23335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV042_RS23355	COG2860	membrane
HV042_RS23375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV042_RS23380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV042_RS23385	COG1120	ATPase activity
HV042_RS23390	COG4774	siderophore transport
HV042_RS23395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HV042_RS23480	COG1643	Atp-dependent helicase
HV042_RS23485	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HV042_RS23505	COG0617	tRNA 3'-terminal CCA addition
HV042_RS23510	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HV042_RS23525	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HV042_RS23530	COG0726	polysaccharide deacetylase
HV042_RS23535	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS23540	COG0842	Transport permease protein
HV042_RS23545	COG1131	(ABC) transporter
HV042_RS23550	COG0288	reversible hydration of carbon dioxide
HV042_RS23560	COG4993	Dehydrogenase
HV042_RS23565	COG2132	Multicopper oxidase
HV042_RS23580	COG0545	Peptidyl-prolyl cis-trans isomerase
HV042_RS23605	COG3064	Membrane
HV042_RS23620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV042_RS23625	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV042_RS23630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HV042_RS23635	COG2186	Transcriptional regulator
HV042_RS23640	COG1113	amino acid transport
HV042_RS23645	COG2211	Major facilitator Superfamily
HV042_RS23650	COG3940	Belongs to the glycosyl hydrolase 43 family
HV042_RS23655	COG3725	Membrane protein required for beta-lactamase induction
HV042_RS23670	COG4969	Belongs to the N-Me-Phe pilin family
HV042_RS23675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV042_RS23680	COG1459	type II secretion system
HV042_RS23705	COG0494	nUDIX hydrolase
HV042_RS23725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HV042_RS23730	COG0849	cell division
HV042_RS23755	COG0772	Belongs to the SEDS family
HV042_RS23770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HV042_RS23780	COG0768	penicillin binding
HV042_RS23800	COG1609	Transcriptional regulator
HV042_RS23810	COG0028	Belongs to the TPP enzyme family
HV042_RS23825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HV042_RS23850	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV042_RS23855	COG0738	Major facilitator superfamily
HV042_RS23865	COG0583	DNA-binding transcription factor activity
HV042_RS23870	COG2271	Major facilitator Superfamily
HV042_RS23875	COG2814	Major facilitator Superfamily
HV042_RS23895	COG1178	ABC-type Fe3 transport system permease component
HV042_RS23905	COG0586	Pfam SNARE associated Golgi protein
HV042_RS23925	COG0235	Class ii aldolase
HV042_RS23930	COG0417	DNA replication proofreading
HV042_RS23940	COG0564	pseudouridine synthase activity
HV042_RS23950	COG3493	citrate carrier protein
HV042_RS23965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HV042_RS24025	COG1940	carbohydrate kinase activity
HV042_RS24100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HV042_RS24115	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HV042_RS24120	COG0471	metal ion transport
HV042_RS24125	COG0471	metal ion transport
HV042_RS24130	COG2828	Protein conserved in bacteria
HV042_RS24135	COG0583	DNA-binding transcription factor activity
HV042_RS24150	COG1047	Peptidyl-prolyl cis-trans
HV042_RS24165	COG0196	riboflavin kinase activity
HV042_RS24175	COG0583	DNA-binding transcription factor activity
HV042_RS24210	COG4735	regulation of single-species biofilm formation
HV042_RS24215	COG1584	GPR1 FUN34 yaaH family protein
HV042_RS24225	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV042_RS24230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HV042_RS24235	COG1115	amino acid carrier protein
HV042_RS24245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HV042_RS24255	COG0460	homoserine dehydrogenase
HV042_RS24255	COG0527	aspartate kinase activity
HV042_RS24265	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HV042_RS24275	COG0745	RESPONSE REGULATOR receiver
HV042_RS24280	COG4452	Inner membrane protein CreD
HV042_RS24285	COG2205	protein histidine kinase activity
HV042_RS24290	COG0745	RESPONSE REGULATOR receiver
HV042_RS24295	COG3045	CreA protein
HV042_RS24300	COG2207	Transcriptional regulator
HV042_RS24300	COG3708	Transcriptional regulator
HV042_RS24320	COG0741	lytic transglycosylase activity
HV042_RS24325	COG0488	(ABC) transporter
HV042_RS24335	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HV042_RS24340	COG0560	Phosphoserine phosphatase
HV042_RS24345	COG3726	membrane protein affecting hemolysin expression
HV042_RS24355	COG0813	purine-nucleoside phosphorylase activity
HV042_RS24375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV042_RS24380	COG0084	hydrolase, TatD family'
HV042_RS24385	COG4667	esterase of the alpha-beta hydrolase superfamily
HV042_RS24390	COG5487	UPF0391 membrane protein
HV042_RS24395	COG2823	Periplasmic or secreted lipoprotein
HV042_RS24405	COG1011	Hydrolase
HV042_RS24410	COG0456	acetyltransferase
HV042_RS24415	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HV042_RS24445	COG3706	GGDEF domain
HV042_RS24450	COG4114	ferric iron reductase
HV042_RS24455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV042_RS24460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV042_RS24465	COG2197	response regulator
HV042_RS24470	COG2197	response regulator
HV042_RS24475	COG2207	Transcriptional regulator
HV042_RS24485	COG2966	Psort location CytoplasmicMembrane, score
HV042_RS24500	COG1484	DNA-dependent DNA replication
HV042_RS24515	COG5464	transposase or invertase
HV042_RS24525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HV042_RS24530	COG3716	PTS system mannose fructose sorbose family IID component
HV042_RS24535	COG3715	PTS system
HV042_RS24550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV042_RS24550	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HV042_RS24560	COG1063	alcohol dehydrogenase
HV042_RS24565	COG1802	Transcriptional regulator
HV042_RS24570	COG2271	Major facilitator Superfamily
HV042_RS24575	COG0456	acetyltransferase
HV042_RS24585	COG1737	Transcriptional regulator
HV042_RS24590	COG0800	Aldolase
HV042_RS24595	COG3734	2-keto-3-deoxy-galactonokinase
HV042_RS24600	COG4145	pantothenate transmembrane transporter activity
HV042_RS24610	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HV042_RS24620	COG1846	Transcriptional regulator
HV042_RS24625	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV042_RS24635	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS24640	COG3384	dioxygenase
HV042_RS24650	COG3971	2-oxopent-4-enoate hydratase activity
HV042_RS24670	COG2368	4-hydroxyphenylacetate
HV042_RS24675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV042_RS24680	COG1966	Carbon starvation protein
HV042_RS24685	COG2879	small protein
HV042_RS24690	COG0523	cobalamin synthesis protein
HV042_RS24705	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS24730	COG2733	membrane
HV042_RS24735	COG2814	Major facilitator Superfamily
HV042_RS24740	COG1475	DNA binding
HV042_RS24745	COG3969	phosphoadenosine phosphosulfate
HV042_RS24755	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HV042_RS24760	COG1924	4 iron, 4 sulfur cluster binding
HV042_RS24770	COG1473	amidohydrolase
HV042_RS24775	COG0700	Nucleoside recognition
HV042_RS24780	COG3366	ferrous iron transmembrane transporter activity
HV042_RS24785	COG0583	DNA-binding transcription factor activity
HV042_RS24795	COG1566	PFAM secretion protein HlyD family protein
HV042_RS24805	COG5457	Domain of unknown function (DUF1127)
HV042_RS24815	COG1715	Restriction endonuclease
HV042_RS24820	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HV042_RS24825	COG0732	type I restriction modification DNA specificity domain
HV042_RS24830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HV042_RS24835	COG1120	ATPase activity
HV042_RS24855	COG0531	amino acid
HV042_RS24870	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV042_RS24905	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS24905	COG1454	alcohol dehydrogenase
HV042_RS24920	COG1882	Formate acetyltransferase
HV042_RS24925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV042_RS24935	COG4869	propanediol catabolic process
HV042_RS24965	COG0814	amino acid
HV042_RS24975	COG3706	GGDEF domain
HV042_RS24980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV042_RS24985	COG0842	Transport permease protein
HV042_RS24985	COG1129	ABC transporter
HV042_RS24990	COG0842	Transport permease protein
HV042_RS25020	COG2850	peptidyl-arginine hydroxylation
HV042_RS25025	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HV042_RS25030	COG0588	phosphoglycerate mutase activity
HV042_RS25040	COG0477	Major facilitator Superfamily
HV042_RS25050	COG0477	Major facilitator Superfamily
HV042_RS25055	COG4948	Mandelate Racemase Muconate Lactonizing
HV042_RS25060	COG1028	Short-chain dehydrogenase reductase Sdr
HV042_RS25065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV042_RS25150	COG0582	viral genome integration into host DNA
HV042_RS25160	COG1064	alcohol dehydrogenase
HV042_RS25165	COG1175	transmembrane transport
HV042_RS25170	COG0395	ABC-type sugar transport system, permease component
HV042_RS25175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HV042_RS25180	COG3842	ATPase activity
HV042_RS25190	COG2814	Major facilitator Superfamily
HV042_RS25200	COG1082	Xylose isomerase domain protein TIM barrel
HV042_RS25210	COG3962	Belongs to the TPP enzyme family
HV042_RS25215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV042_RS25220	COG1737	Transcriptional regulator
HV042_RS25220	COG0837	glucose binding
HV042_RS25225	COG3718	enzyme involved in inositol metabolism
HV042_RS25240	COG0433	COG0433 Predicted ATPase
HV042_RS25245	COG0795	lipopolysaccharide-transporting ATPase activity
HV042_RS25250	COG0795	lipopolysaccharide-transporting ATPase activity
HV042_RS25260	COG2927	DNA polymerase III (CHI subunit)
HV042_RS25265	COG0525	valine-tRNA ligase activity
HV042_RS25290	COG2731	YhcH YjgK YiaL family protein
HV042_RS25315	COG0251	oxidation-reduction process
HV042_RS25325	COG1609	Transcriptional regulator
HV042_RS25330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV042_RS25330	COG1263	PTS System
HV042_RS25335	COG0366	Alpha amylase catalytic
HV042_RS25340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV042_RS25345	COG1486	melibiose metabolic process
HV042_RS25365	COG0602	queuosine metabolic process
HV042_RS25370	COG3501	Rhs element vgr protein
HV042_RS25385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV042_RS25385	COG3711	transcriptional antiterminator
HV042_RS25390	COG2706	6-phosphogluconolactonase activity
HV042_RS25405	COG3964	amidohydrolase
HV042_RS25440	COG0312	modulator of DNA gyrase
HV042_RS25450	COG1012	belongs to the aldehyde dehydrogenase family
HV042_RS25470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HV042_RS25480	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS25485	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS25490	COG1129	ABC transporter
HV042_RS25495	COG1879	ABC-type sugar transport system periplasmic component
HV042_RS25505	COG2105	PFAM AIG2 family protein
HV042_RS25510	COG2911	Protein conserved in bacteria
HV042_RS25515	COG0729	surface antigen
HV042_RS25525	COG1253	flavin adenine dinucleotide binding
HV042_RS25550	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HV042_RS25565	COG1733	regulation of RNA biosynthetic process
HV042_RS25570	COG0702	epimerase
HV042_RS25580	COG0697	spore germination
HV042_RS25590	COG1113	amino acid transport
HV042_RS25595	COG0545	Peptidyl-prolyl cis-trans isomerase
HV042_RS25600	COG3061	Opacity-associated protein A
HV042_RS25610	COG0359	binds to the 23S rRNA
HV042_RS25615	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HV042_RS25620	COG2965	DNA replication, synthesis of RNA primer
HV042_RS25680	COG1073	alpha beta
HV042_RS25685	COG3650	response to hydrogen peroxide
HV042_RS25695	COG1960	acyl-CoA dehydrogenase activity
HV042_RS25705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV042_RS25710	COG0557	exoribonuclease II activity
HV042_RS25725	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HV042_RS25735	COG0330	HflC and HflK could
HV042_RS25740	COG0330	HflC and HflK could
HV042_RS25745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HV042_RS25765	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV042_RS25770	COG0802	atpase or kinase
HV042_RS25775	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HV042_RS25775	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HV042_RS25780	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HV042_RS25800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV042_RS25805	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HV042_RS25820	COG3264	Mechanosensitive ion channel
HV042_RS25820	COG1511	domain protein
HV042_RS25830	COG1053	succinate dehydrogenase
HV042_RS25835	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV042_RS25850	COG3040	lipid binding
HV042_RS25855	COG2076	Multidrug Resistance protein
HV042_RS25890	COG3039	Transposase
HV042_RS25950	COG0459	protein refolding
HV042_RS25960	COG0531	amino acid
HV042_RS25975	COG3030	protein affecting phage T7 exclusion by the F plasmid
HV042_RS25980	COG1027	Aspartate ammonia-lyase
HV042_RS25985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV042_RS26000	COG1309	transcriptional regulator
HV042_RS26015	COG5301	cellulose 1,4-beta-cellobiosidase activity
HV042_RS26020	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HV042_RS26025	COG5301	cellulose 1,4-beta-cellobiosidase activity
HV042_RS26035	COG3299	homolog of phage Mu protein gp47
HV042_RS26065	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
HV042_RS26075	COG4386	tail sheath protein
HV042_RS26105	COG4397	Mu-like prophage major head subunit gpT
HV042_RS26130	COG4373	Mu-like prophage FluMu protein gp28
HV042_RS26145	COG0640	Transcriptional regulator
HV042_RS26215	COG2842	Transposition protein
HV042_RS26225	COG3423	Transcriptional regulator
HV042_RS26245	COG0463	Glycosyl transferase, family 2
HV042_RS26260	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV042_RS26275	COG0861	Integral membrane protein TerC family
HV042_RS26295	COG2824	Alkylphosphonate utilization operon protein PhnA
HV042_RS26300	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HV042_RS26305	COG2188	Transcriptional regulator
HV042_RS26310	COG3624	Phosphonate C-P lyase system protein PhnG
HV042_RS26315	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HV042_RS26320	COG3626	phosphonate metabolism
HV042_RS26325	COG3627	carbon phosphorus lyase activity
HV042_RS26330	COG4107	phosphonate C-P lyase system protein PhnK
HV042_RS26335	COG4778	phosphonate C-P lyase system protein PhnL
HV042_RS26340	COG3454	Phosphonate metabolism
HV042_RS26345	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HV042_RS26350	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HV042_RS26360	COG0698	ribose 5-phosphate isomerase
HV042_RS26365	COG1737	Transcriptional regulator
HV042_RS26370	COG1879	ABC-type sugar transport system periplasmic component
HV042_RS26375	COG1129	ABC transporter
HV042_RS26380	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS26385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV042_RS26390	COG1940	carbohydrate kinase activity
HV042_RS26395	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HV042_RS26405	COG1566	PFAM secretion protein HlyD family protein
HV042_RS26410	COG1289	transmembrane transporter activity
HV042_RS26425	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HV042_RS26430	COG1301	dicarboxylic acid transport
HV042_RS26435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HV042_RS26440	COG3162	membrane
HV042_RS26445	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV042_RS26480	COG1380	Effector of murein hydrolase LrgA
HV042_RS26485	COG0583	DNA-binding transcription factor activity
HV042_RS26505	COG3039	Transposase
HV042_RS26520	COG0025	NhaP-type Na H and K H
HV042_RS26525	COG2252	PERMEase
HV042_RS26545	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV042_RS26560	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV042_RS26570	COG4771	TonB-dependent receptor
HV042_RS26580	COG0629	single-stranded DNA binding
HV042_RS26585	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HV042_RS26600	COG2315	Protein conserved in bacteria
HV042_RS26605	COG0432	Pfam Uncharacterised protein family UPF0047
HV042_RS26615	COG1448	Aminotransferase
HV042_RS26620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HV042_RS26625	COG0305	Participates in initiation and elongation during chromosome replication
HV042_RS26640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV042_RS26650	COG0735	belongs to the Fur family
HV042_RS26655	COG3237	CsbD-like
HV042_RS26660	COG0534	Mate efflux family protein
HV042_RS26670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HV042_RS26695	COG4580	involved in the transport of maltose and maltodextrins
HV042_RS26730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HV042_RS26740	COG0527	aspartate kinase activity
HV042_RS26745	COG3541	Predicted nucleotidyltransferase
HV042_RS26760	COG4650	regulator
HV042_RS26775	COG1187	pseudouridine synthase activity
HV042_RS26815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV042_RS26870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HV042_RS26910	COG0151	Belongs to the GarS family
HV042_RS26920	COG4191	Histidine kinase
HV042_RS26960	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HV042_RS26975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV042_RS26980	COG2104	thiamine diphosphate biosynthetic process
HV042_RS26995	COG3706	GGDEF domain
HV042_RS27005	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV042_RS27010	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV042_RS27045	COG0250	Participates in transcription elongation, termination and antitermination
HV042_RS27050	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HV042_RS27090	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HV042_RS27120	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HV042_RS27130	COG1739	Uncharacterized protein family UPF0029
HV042_RS27175	COG0805	protein transport
HV042_RS27180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HV042_RS27195	COG3165	ubiquinone biosynthetic process from chorismate
HV042_RS27215	COG0412	Dienelactone hydrolase
HV042_RS27230	COG0583	DNA-binding transcription factor activity
HV042_RS27235	COG0697	spore germination
HV042_RS27240	COG0561	phosphatase activity
HV042_RS27245	COG2267	carboxylic ester hydrolase activity
HV042_RS27250	COG1280	lysine exporter protein (LysE YggA)
HV042_RS27260	COG1280	lysine exporter protein (LysE YggA)
HV042_RS27275	COG2050	protein possibly involved in aromatic compounds catabolism
HV042_RS27285	COG0598	Magnesium transport protein CorA
HV042_RS27290	COG0210	DNA helicase
HV042_RS27295	COG1011	Hydrolase
HV042_RS27315	COG5567	small periplasmic lipoprotein
HV042_RS27325	COG3072	Adenylate cyclase
HV042_RS27335	COG1587	Uroporphyrinogen-III synthase
HV042_RS27340	COG2959	enzyme of heme biosynthesis
HV042_RS27345	COG3071	HemY protein
HV042_RS27390	COG2244	polysaccharide biosynthetic process
HV042_RS27395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HV042_RS27400	COG0456	acetyltransferase
HV042_RS27405	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HV042_RS27410	COG1088	dTDP-glucose 4,6-dehydratase activity
HV042_RS27415	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HV042_RS27420	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HV042_RS27430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HV042_RS27435	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HV042_RS27440	COG3118	belongs to the thioredoxin family
HV042_RS27455	COG0583	DNA-binding transcription factor activity
HV042_RS27465	COG1811	Na channel or pump
HV042_RS27475	COG1397	ADP-ribosylglycohydrolase
HV042_RS27485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV042_RS27510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV042_RS27515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV042_RS27525	COG0583	DNA-binding transcription factor activity
HV042_RS27530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV042_RS27540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV042_RS27545	COG3978	acetolactate synthase activity
HV042_RS27565	COG3085	chromosome segregation
HV042_RS27640	COG0583	DNA-binding transcription factor activity
HV042_RS27655	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HV042_RS27670	COG3443	Belongs to the bacterial solute-binding protein 9 family
HV042_RS27675	COG2207	Transcriptional regulator
HV042_RS27685	COG0371	Dehydrogenase
HV042_RS27690	COG1349	DNA-binding transcription factor activity
HV042_RS27700	COG0583	DNA-binding transcription factor activity
HV042_RS27705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV042_RS27710	COG0527	aspartate kinase activity
HV042_RS27710	COG0460	homoserine dehydrogenase
HV042_RS27715	COG0626	cystathionine gamma-synthase activity
HV042_RS27730	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HV042_RS27735	COG1609	Transcriptional regulator
HV042_RS27740	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV042_RS27755	COG1575	Belongs to the MenA family. Type 1 subfamily
HV042_RS27915	COG4695	Portal protein
HV042_RS27950	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV042_RS28000	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HV042_RS28005	COG3678	ATP-independent chaperone mediated protein folding
HV042_RS28010	COG0745	RESPONSE REGULATOR receiver
HV042_RS28015	COG2205	protein histidine kinase activity
HV042_RS28020	COG2258	MOSC domain
HV042_RS28065	COG1129	ABC transporter
HV042_RS28080	COG1454	alcohol dehydrogenase
HV042_RS28095	COG2211	Major facilitator Superfamily
HV042_RS28110	COG0110	maltose O-acetyltransferase activity
HV042_RS28115	COG2211	Major facilitator Superfamily
HV042_RS28135	COG2731	YhcH YjgK YiaL family protein
HV042_RS28140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV042_RS28145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV042_RS28155	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV042_RS28195	COG0205	6-phosphofructokinase activity
HV042_RS28220	COG3715	PTS system
HV042_RS28225	COG3716	PTS system mannose fructose sorbose family IID component
HV042_RS28255	COG0437	4 iron, 4 sulfur cluster binding
HV042_RS28260	COG2864	formate dehydrogenase
HV042_RS28275	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV042_RS28285	COG0456	acetyltransferase
HV042_RS28290	COG1490	D-aminoacyl-tRNA deacylase activity
HV042_RS28300	COG1011	Hydrolase
HV042_RS28315	COG3852	Histidine kinase
HV042_RS28330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV042_RS28350	COG0204	Acyl-transferase
HV042_RS28360	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HV042_RS28365	COG3084	Protein conserved in bacteria
HV042_RS28375	COG1763	Mo-molybdopterin cofactor biosynthetic process
HV042_RS28395	COG2186	Transcriptional regulator
HV042_RS28400	COG0477	Major facilitator Superfamily
HV042_RS28405	COG1609	Transcriptional regulator
HV042_RS28410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV042_RS28420	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV042_RS28425	COG1129	ABC transporter
HV042_RS28455	COG1522	sequence-specific DNA binding
HV042_RS28460	COG0716	FMN binding
HV042_RS28475	COG3312	ion transport
HV042_RS28535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HV042_RS28540	COG0573	inorganic phosphate transmembrane transporter activity
HV042_RS28545	COG0581	inorganic phosphate transmembrane transporter activity
HV042_RS28550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HV042_RS28555	COG0704	Plays a role in the regulation of phosphate uptake
HV042_RS28570	COG2382	esterase
HV042_RS28575	COG0363	glucosamine-6-phosphate deaminase activity
HV042_RS28580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV042_RS28585	COG2252	PERMEase
HV042_RS28590	COG0431	NADPH-dependent FMN reductase
HV042_RS28595	COG2091	lysine biosynthetic process via aminoadipic acid
HV042_RS28610	COG2731	YhcH YjgK YiaL family protein
HV042_RS28630	COG1737	Transcriptional regulator
HV042_RS28635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV042_RS28640	COG0456	acetyltransferase
HV042_RS28655	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HV042_RS28665	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HV042_RS28685	COG0739	heme binding
HV042_RS28695	COG2132	Multicopper oxidase
HV042_RS28700	COG3667	copper resistance
HV042_RS28705	COG2372	response to copper ion
HV042_RS28710	COG1276	copper resistance
HV042_RS28715	COG0745	RESPONSE REGULATOR receiver
HV042_RS28720	COG2205	protein histidine kinase activity
HV042_RS28730	COG3039	Transposase
HV042_RS28815	COG2801	Transposase and inactivated derivatives
HV042_RS28855	COG0789	Transcriptional regulator
HV042_RS28960	COG0071	Belongs to the small heat shock protein (HSP20) family
HV042_RS28965	COG0542	response to heat
HV042_RS29020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV042_RS29040	COG1609	Transcriptional regulator
HV042_RS29050	COG2223	nitrite transmembrane transporter activity
HV042_RS29140	COG3039	Transposase
HV042_RS29390	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV042_RS29415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HV042_RS29505	COG1528	Iron-storage protein
HV042_RS29510	COG3039	Transposase
HV042_RS29530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV042_RS29535	COG1127	ABC transporter
HV042_RS29590	COG1192	Involved in chromosome partitioning
HV042_RS30115	COG1528	Iron-storage protein
HV042_RS30120	COG3039	Transposase
HV042_RS30250	COG0629	single-stranded DNA binding
HV042_RS30570	COG0489	protein tyrosine kinase activity