locus-tag	class	description
HV234_RS00010	COG0592	DNA-directed DNA polymerase activity
HV234_RS00025	COG0583	DNA-binding transcription factor activity
HV234_RS00035	COG0561	phosphatase activity
HV234_RS00040	COG2186	Transcriptional regulator
HV234_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
HV234_RS00050	COG0800	Aldolase
HV234_RS00065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HV234_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
HV234_RS00075	COG5645	(Lipo)protein
HV234_RS00100	COG2188	Transcriptional regulator
HV234_RS00115	COG2149	membrane
HV234_RS00125	COG0641	radical SAM
HV234_RS00135	COG2610	gluconate transmembrane transporter activity
HV234_RS00140	COG0583	DNA-binding transcription factor activity
HV234_RS00150	COG2814	Major facilitator Superfamily
HV234_RS00175	COG0028	Belongs to the TPP enzyme family
HV234_RS00180	COG0440	acetolactate synthase activity
HV234_RS00190	COG2197	response regulator
HV234_RS00200	COG2271	Major facilitator Superfamily
HV234_RS00230	COG4580	involved in the transport of maltose and maltodextrins
HV234_RS00235	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV234_RS00240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV234_RS00240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV234_RS00250	COG1609	Transcriptional regulator
HV234_RS00260	COG5464	transposase or invertase
HV234_RS00270	COG0697	spore germination
HV234_RS00275	COG1263	PTS System
HV234_RS00275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV234_RS00285	COG2814	Major facilitator Superfamily
HV234_RS00295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV234_RS00300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV234_RS00310	COG1309	transcriptional regulator
HV234_RS00320	COG0583	DNA-binding transcription factor activity
HV234_RS00335	COG1464	Belongs to the NlpA lipoprotein family
HV234_RS00350	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HV234_RS00375	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HV234_RS00395	COG2211	Major facilitator Superfamily
HV234_RS00400	COG1501	Belongs to the glycosyl hydrolase 31 family
HV234_RS00415	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV234_RS00420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV234_RS00420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV234_RS00435	COG1940	carbohydrate kinase activity
HV234_RS00450	COG1486	melibiose metabolic process
HV234_RS00455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV234_RS00455	COG1263	PTS System
HV234_RS00465	COG2233	PERMEase
HV234_RS00470	COG0786	glutamate:sodium symporter activity
HV234_RS00485	COG3074	FtsZ-dependent cytokinesis
HV234_RS00500	COG2211	Major facilitator Superfamily
HV234_RS00505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV234_RS00515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV234_RS00535	COG3152	Membrane
HV234_RS00545	COG1494	fructose-1,6-bisphosphatase
HV234_RS00550	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HV234_RS00555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV234_RS00560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV234_RS00580	COG2860	membrane
HV234_RS00590	COG1561	YicC-like family, N-terminal region
HV234_RS00600	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HV234_RS00615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HV234_RS00625	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HV234_RS00630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HV234_RS00635	COG4245	von Willebrand factor, type A
HV234_RS00670	COG1519	Transferase
HV234_RS00675	COG1216	Glycosyl transferase, family 2
HV234_RS00680	COG0438	transferase activity, transferring glycosyl groups
HV234_RS00690	COG0859	PFAM glycosyl transferase family 9
HV234_RS00715	COG0859	PFAM glycosyl transferase family 9
HV234_RS00720	COG0859	PFAM glycosyl transferase family 9
HV234_RS00740	COG0463	Glycosyl transferase, family 2
HV234_RS00745	COG2861	carbohydrate metabolic process
HV234_RS00750	COG4942	peptidase
HV234_RS00760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV234_RS00765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV234_RS00785	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HV234_RS00795	COG2186	Transcriptional regulator
HV234_RS00815	COG3722	fumarate hydratase activity
HV234_RS00835	COG1566	PFAM secretion protein HlyD family protein
HV234_RS00840	COG0625	glutathione transferase activity
HV234_RS00850	COG3276	selenocysteine insertion sequence binding
HV234_RS00860	COG2211	Major facilitator Superfamily
HV234_RS00865	COG4977	sequence-specific DNA binding
HV234_RS00865	COG1917	Cupin 2, conserved barrel domain protein
HV234_RS00870	COG0235	Class ii aldolase
HV234_RS00875	COG3623	hexulose-6-phosphate isomerase
HV234_RS00880	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HV234_RS00885	COG1070	Carbohydrate kinase
HV234_RS00900	COG2731	YhcH YjgK YiaL family protein
HV234_RS00905	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV234_RS00910	COG1414	Transcriptional regulator
HV234_RS00915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV234_RS00920	COG3977	Valine--pyruvate aminotransferase
HV234_RS00925	COG0366	Alpha amylase catalytic
HV234_RS00930	COG2992	FlgJ-related protein
HV234_RS00935	COG1609	Transcriptional regulator
HV234_RS00935	COG2207	Transcriptional regulator
HV234_RS00940	COG4214	carbohydrate transport
HV234_RS00950	COG4213	ABC transporter substrate-binding protein
HV234_RS00955	COG2115	Belongs to the xylose isomerase family
HV234_RS00960	COG1070	Carbohydrate kinase
HV234_RS00965	COG4682	membrane
HV234_RS00970	COG3274	enterobacterial common antigen metabolic process
HV234_RS01000	COG1278	Cold shock
HV234_RS01005	COG2944	sequence-specific DNA binding
HV234_RS01010	COG2814	Major facilitator Superfamily
HV234_RS01030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV234_RS01040	COG1609	Transcriptional regulator
HV234_RS01045	COG2885	chlorophyll binding
HV234_RS01050	COG0243	molybdopterin cofactor binding
HV234_RS01055	COG0456	acetyltransferase
HV234_RS01060	COG2818	Glycosylase
HV234_RS01070	COG2223	nitrite transmembrane transporter activity
HV234_RS01085	COG0747	negative chemotaxis
HV234_RS01090	COG0601	transmembrane transport
HV234_RS01095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV234_RS01100	COG0444	Belongs to the ABC transporter superfamily
HV234_RS01105	COG4608	Belongs to the ABC transporter superfamily
HV234_RS01115	COG0489	protein tyrosine kinase activity
HV234_RS01130	COG0457	Tetratricopeptide repeat
HV234_RS01155	COG2194	sulfuric ester hydrolase activity
HV234_RS01185	COG1215	transferase activity, transferring glycosyl groups
HV234_RS01190	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HV234_RS01195	COG3118	belongs to the thioredoxin family
HV234_RS01195	COG0457	Tetratricopeptide repeat
HV234_RS01200	COG2200	EAL domain
HV234_RS01200	COG2199	diguanylate cyclase activity
HV234_RS01210	COG0612	Peptidase, M16
HV234_RS01220	COG2982	Protein involved in outer membrane biogenesis
HV234_RS01225	COG0477	Major facilitator Superfamily
HV234_RS01230	COG1295	ribonuclease BN
HV234_RS01235	COG0583	DNA-binding transcription factor activity
HV234_RS01240	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS01245	COG2197	response regulator
HV234_RS01265	COG1454	alcohol dehydrogenase
HV234_RS01275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV234_RS01280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HV234_RS01285	COG0671	phosphoesterase, PA-phosphatase related
HV234_RS01290	COG2205	protein histidine kinase activity
HV234_RS01295	COG0745	RESPONSE REGULATOR receiver
HV234_RS01300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV234_RS01305	COG2183	response to ionizing radiation
HV234_RS01310	COG1918	ferrous iron import across plasma membrane
HV234_RS01335	COG1040	competence protein
HV234_RS01345	COG2610	gluconate transmembrane transporter activity
HV234_RS01370	COG1959	2 iron, 2 sulfur cluster binding
HV234_RS01380	COG0589	response to stress
HV234_RS01390	COG0306	phosphate transporter
HV234_RS01395	COG2081	HI0933 family
HV234_RS01400	COG2204	response regulator
HV234_RS01405	COG3964	amidohydrolase
HV234_RS01410	COG0471	metal ion transport
HV234_RS01415	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HV234_RS01420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV234_RS01430	COG2239	Acts as a magnesium transporter
HV234_RS01445	COG0444	Belongs to the ABC transporter superfamily
HV234_RS01450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV234_RS01455	COG0601	transmembrane transport
HV234_RS01460	COG0747	negative chemotaxis
HV234_RS01470	COG3479	Phenolic acid decarboxylase
HV234_RS01510	COG0628	permease
HV234_RS01515	COG0477	Major facilitator Superfamily
HV234_RS01525	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HV234_RS01540	COG3714	YhhN family
HV234_RS01550	COG3776	membrane
HV234_RS01555	COG0742	ribosomal rna small subunit methyltransferase
HV234_RS01560	COG0552	protein localization to endoplasmic reticulum
HV234_RS01565	COG2884	Cell division ATP-binding protein ftsE
HV234_RS01570	COG2177	Part of the ABC transporter FtsEX involved in
HV234_RS01585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV234_RS01600	COG0683	leucine binding
HV234_RS01635	COG2721	sulfolactate sulfo-lyase activity
HV234_RS01640	COG2271	Major facilitator Superfamily
HV234_RS01645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV234_RS01650	COG1414	Transcriptional regulator
HV234_RS01675	COG0584	glycerophosphoryl diester phosphodiesterase
HV234_RS01685	COG0405	Gamma-glutamyltransferase
HV234_RS01690	COG1247	-acetyltransferase
HV234_RS01700	COG0673	inositol 2-dehydrogenase activity
HV234_RS01705	COG1741	Belongs to the pirin family
HV234_RS01710	COG1609	Transcriptional regulator
HV234_RS01715	COG3265	gluconokinase activity
HV234_RS01720	COG2610	gluconate transmembrane transporter activity
HV234_RS01735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV234_RS01760	COG0058	SHG alpha-glucan phosphorylase activity
HV234_RS01765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV234_RS01780	COG1349	DNA-binding transcription factor activity
HV234_RS01790	COG0058	SHG alpha-glucan phosphorylase activity
HV234_RS01795	COG1640	4-alpha-glucanotransferase
HV234_RS01810	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HV234_RS01815	COG1011	Hydrolase
HV234_RS01825	COG0494	nUDIX hydrolase
HV234_RS01830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HV234_RS01840	COG3166	PFAM Fimbrial assembly family protein
HV234_RS01855	COG4796	Type ii and iii secretion system protein
HV234_RS01870	COG3266	domain, Protein
HV234_RS01875	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV234_RS01880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV234_RS01905	COG2146	nitrite reductase [NAD(P)H] activity
HV234_RS01910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV234_RS01915	COG0402	S-adenosylhomocysteine deaminase activity
HV234_RS01920	COG0738	Major facilitator superfamily
HV234_RS01945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HV234_RS01950	COG1289	transmembrane transporter activity
HV234_RS01960	COG1765	OsmC-like protein
HV234_RS01965	COG3954	Phosphoribulokinase
HV234_RS01975	COG0429	hydrolase of the alpha beta-hydrolase fold
HV234_RS01985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HV234_RS01995	COG0488	(ABC) transporter
HV234_RS02010	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HV234_RS02015	COG1047	Peptidyl-prolyl cis-trans
HV234_RS02025	COG0545	Peptidyl-prolyl cis-trans isomerase
HV234_RS02030	COG2964	Protein conserved in bacteria
HV234_RS02085	COG0051	transcription antitermination factor activity, RNA binding
HV234_RS02095	COG0088	Forms part of the polypeptide exit tunnel
HV234_RS02110	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HV234_RS02125	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HV234_RS02175	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HV234_RS02190	COG0201	protein transport
HV234_RS02205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HV234_RS02215	COG0202	RNA polymerase activity
HV234_RS02220	COG0203	ribosomal protein L17
HV234_RS02230	COG0789	Transcriptional regulator
HV234_RS02235	COG3036	rescue of stalled ribosome
HV234_RS02265	COG0758	DNA mediated transformation
HV234_RS02275	COG0551	DNA topoisomerase type I activity
HV234_RS02295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV234_RS02335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV234_RS02340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV234_RS02345	COG1309	transcriptional regulator
HV234_RS02370	COG4145	pantothenate transmembrane transporter activity
HV234_RS02375	COG3924	membrane
HV234_RS02380	COG0439	Biotin carboxylase
HV234_RS02385	COG0511	ligase activity, forming carbon-carbon bonds
HV234_RS02400	COG0604	alcohol dehydrogenase
HV234_RS02405	COG2199	diguanylate cyclase activity
HV234_RS02405	COG2200	EAL domain
HV234_RS02410	COG1077	Cell shape determining protein MreB Mrl
HV234_RS02415	COG1792	Involved in formation and maintenance of cell shape
HV234_RS02420	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HV234_RS02430	COG1530	ribonuclease E activity
HV234_RS02435	COG3164	Protein of unknown function
HV234_RS02440	COG0312	modulator of DNA gyrase
HV234_RS02445	COG1349	DNA-binding transcription factor activity
HV234_RS02450	COG0583	DNA-binding transcription factor activity
HV234_RS02465	COG1289	transmembrane transporter activity
HV234_RS02470	COG2732	(Barnase) inhibitor
HV234_RS02495	COG2188	Transcriptional regulator
HV234_RS02505	COG0471	metal ion transport
HV234_RS02510	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV234_RS02515	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV234_RS02540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV234_RS02545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV234_RS02550	COG3105	Protein conserved in bacteria
HV234_RS02555	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HV234_RS02570	COG0625	glutathione transferase activity
HV234_RS02575	COG2969	positive regulation of protein catabolic process
HV234_RS02585	COG0493	'glutamate synthase
HV234_RS02590	COG0070	glutamate synthase
HV234_RS02590	COG0069	glutamate synthase activity
HV234_RS02590	COG0067	glutamate synthase
HV234_RS02595	COG1242	4 iron, 4 sulfur cluster binding
HV234_RS02600	COG5002	protein histidine kinase activity
HV234_RS02600	COG2198	Histidine kinase
HV234_RS02600	COG0784	Response regulator, receiver
HV234_RS02605	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HV234_RS02610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HV234_RS02615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS02620	COG1660	Displays ATPase and GTPase activities
HV234_RS02625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS02630	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV234_RS02635	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HV234_RS02640	COG1137	ATPase activity
HV234_RS02645	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HV234_RS02650	COG3117	lipopolysaccharide transmembrane transporter activity
HV234_RS02655	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HV234_RS02665	COG0530	calcium, potassium:sodium antiporter activity
HV234_RS02670	COG1127	ABC transporter
HV234_RS02675	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV234_RS02680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV234_RS02685	COG2854	intermembrane phospholipid transfer
HV234_RS02690	COG3113	response to antibiotic
HV234_RS02695	COG5007	Belongs to the BolA IbaG family
HV234_RS02705	COG3423	Transcriptional regulator
HV234_RS02710	COG0142	geranyltranstransferase activity
HV234_RS02725	COG0697	spore germination
HV234_RS02735	COG2027	D-alanyl-D-alanine carboxypeptidase
HV234_RS02745	COG1534	Rna-binding protein
HV234_RS02755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HV234_RS02760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HV234_RS02770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HV234_RS02795	COG0195	Participates in both transcription termination and antitermination
HV234_RS02800	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HV234_RS02835	COG0513	Belongs to the DEAD box helicase family
HV234_RS02840	COG0814	amino acid
HV234_RS02865	COG0511	ligase activity, forming carbon-carbon bonds
HV234_RS02910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV234_RS02915	COG0826	peptidase U32
HV234_RS02920	COG0826	peptidase U32
HV234_RS02925	COG3154	lipid carrier protein
HV234_RS02930	COG3153	acetyltransferase
HV234_RS02935	COG2827	Endonuclease containing a URI domain
HV234_RS02945	COG0693	protein deglycase activity
HV234_RS02950	COG0702	epimerase
HV234_RS02955	COG0701	Predicted permease
HV234_RS02960	COG2823	Periplasmic or secreted lipoprotein
HV234_RS02980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HV234_RS02995	COG1063	alcohol dehydrogenase
HV234_RS03000	COG3775	system Galactitol-specific IIC component
HV234_RS03005	COG3414	Phosphotransferase system galactitol-specific IIB component
HV234_RS03010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS03015	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
HV234_RS03020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS03020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS03025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV234_RS03025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV234_RS03025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS03035	COG0191	fructose-bisphosphate aldolase activity
HV234_RS03040	COG1349	DNA-binding transcription factor activity
HV234_RS03045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV234_RS03050	COG2721	sulfolactate sulfo-lyase activity
HV234_RS03075	COG2084	Dehydrogenase
HV234_RS03080	COG1929	Belongs to the glycerate kinase type-1 family
HV234_RS03105	COG1741	Belongs to the pirin family
HV234_RS03110	COG0583	DNA-binding transcription factor activity
HV234_RS03115	COG3152	Membrane
HV234_RS03120	COG0435	Glutathione S-transferase
HV234_RS03125	COG2259	Doxx family
HV234_RS03135	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HV234_RS03140	COG4575	ribosome binding
HV234_RS03145	COG1422	Protein of unknown function (DUF1090)
HV234_RS03155	COG0586	Pfam SNARE associated Golgi protein
HV234_RS03160	COG2186	Transcriptional regulator
HV234_RS03165	COG2271	Major facilitator Superfamily
HV234_RS03175	COG2721	sulfolactate sulfo-lyase activity
HV234_RS03195	COG0673	inositol 2-dehydrogenase activity
HV234_RS03200	COG1451	nucleotide metabolic process
HV234_RS03205	COG3507	Belongs to the glycosyl hydrolase 43 family
HV234_RS03215	COG2211	Major facilitator Superfamily
HV234_RS03225	COG0446	pyridine nucleotide-disulphide oxidoreductase
HV234_RS03225	COG1902	pentaerythritol trinitrate reductase activity
HV234_RS03245	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS03275	COG1695	Transcriptional regulator
HV234_RS03280	COG2375	cellular response to nickel ion
HV234_RS03295	COG1461	Dihydroxyacetone kinase
HV234_RS03300	COG2376	Dihydroxyacetone kinase
HV234_RS03335	COG4983	Phage plasmid primase, P4 family domain protein
HV234_RS03345	COG1061	Type III restriction enzyme res subunit
HV234_RS03355	COG0789	Transcriptional regulator
HV234_RS03455	COG3039	Transposase
HV234_RS03460	COG3596	GTP binding
HV234_RS03465	COG2378	regulation of single-species biofilm formation
HV234_RS03475	COG2378	regulation of single-species biofilm formation
HV234_RS03500	COG2003	Belongs to the UPF0758 family
HV234_RS03555	COG0358	DNA primase activity
HV234_RS03560	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HV234_RS03615	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV234_RS03630	COG4991	sh3 domain protein
HV234_RS03635	COG3025	triphosphatase activity
HV234_RS03660	COG2960	long-chain fatty acid transporting porin activity
HV234_RS03670	COG3539	Fimbrial protein
HV234_RS03675	COG3121	Chaperone
HV234_RS03680	COG3188	usher protein
HV234_RS03685	COG3539	Fimbrial protein
HV234_RS03690	COG3384	dioxygenase
HV234_RS03695	COG0754	glutathionylspermidine amidase activity
HV234_RS03710	COG0494	nUDIX hydrolase
HV234_RS03715	COG3151	Protein conserved in bacteria
HV234_RS03720	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HV234_RS03725	COG3150	esterase
HV234_RS03730	COG0187	DNA topoisomerase II activity
HV234_RS03745	COG2211	Major facilitator Superfamily
HV234_RS03750	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV234_RS03755	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HV234_RS03760	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV234_RS03765	COG0642	Histidine kinase
HV234_RS03775	COG3111	PFAM Bacterial OB fold (BOF) protein
HV234_RS03785	COG0204	Acyl-transferase
HV234_RS03790	COG2132	Multicopper oxidase
HV234_RS03795	COG1032	radical SAM domain protein
HV234_RS03805	COG1979	alcohol dehydrogenase
HV234_RS03810	COG2207	Transcriptional regulator
HV234_RS03815	COG0586	Pfam SNARE associated Golgi protein
HV234_RS03830	COG0848	biopolymer transport protein
HV234_RS03850	COG0625	glutathione transferase activity
HV234_RS03860	COG0754	glutathionylspermidine amidase activity
HV234_RS03865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV234_RS03890	COG0626	cystathionine gamma-synthase activity
HV234_RS03900	COG0471	metal ion transport
HV234_RS03935	COG0582	viral genome integration into host DNA
HV234_RS03945	COG1811	Na channel or pump
HV234_RS03950	COG1982	Orn Lys Arg decarboxylase major
HV234_RS03955	COG2211	Major facilitator Superfamily
HV234_RS03970	COG1194	a g-specific adenine glycosylase
HV234_RS03980	COG3171	Protein conserved in bacteria
HV234_RS03995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HV234_RS04000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HV234_RS04005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV234_RS04020	COG0762	integral membrane protein
HV234_RS04025	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HV234_RS04030	COG2805	Type II/IV secretion system protein
HV234_RS04035	COG2197	response regulator
HV234_RS04055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HV234_RS04060	COG2356	endonuclease I
HV234_RS04070	COG2814	Major facilitator Superfamily
HV234_RS04090	COG1166	arginine decarboxylase activity
HV234_RS04100	COG0501	Belongs to the peptidase M48B family
HV234_RS04105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV234_RS04110	COG1122	ATPase activity
HV234_RS04115	COG1122	ATPase activity
HV234_RS04145	COG0191	fructose-bisphosphate aldolase activity
HV234_RS04150	COG0668	transmembrane transport
HV234_RS04160	COG2968	Membrane
HV234_RS04165	COG0583	DNA-binding transcription factor activity
HV234_RS04170	COG0427	acetyl-CoA hydrolase
HV234_RS04175	COG1024	Enoyl-CoA hydratase
HV234_RS04180	COG1703	isobutyryl-CoA mutase activity
HV234_RS04185	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV234_RS04185	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV234_RS04200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV234_RS04205	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HV234_RS04225	COG0006	proline dipeptidase activity
HV234_RS04230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV234_RS04235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV234_RS04255	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS04260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HV234_RS04265	COG2723	6-phospho-beta-galactosidase activity
HV234_RS04270	COG1737	Transcriptional regulator
HV234_RS04280	COG1272	protein, Hemolysin III
HV234_RS04290	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HV234_RS04300	COG0716	FMN binding
HV234_RS04315	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HV234_RS04335	COG1811	Na channel or pump
HV234_RS04345	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV234_RS04350	COG0583	DNA-binding transcription factor activity
HV234_RS04355	COG4942	peptidase
HV234_RS04365	COG0582	viral genome integration into host DNA
HV234_RS04420	COG0842	Transport permease protein
HV234_RS04425	COG0842	Transport permease protein
HV234_RS04425	COG1129	ABC transporter
HV234_RS04430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV234_RS04475	COG3539	Fimbrial protein
HV234_RS04530	COG3311	Transcriptional regulator
HV234_RS04540	COG4983	Phage plasmid primase, P4 family domain protein
HV234_RS04565	COG2003	Belongs to the UPF0758 family
HV234_RS04595	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV234_RS04610	COG2223	nitrite transmembrane transporter activity
HV234_RS04615	COG3835	regulator
HV234_RS04620	COG1929	Belongs to the glycerate kinase type-1 family
HV234_RS04665	COG0738	Major facilitator superfamily
HV234_RS04670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV234_RS04675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV234_RS04680	COG1349	DNA-binding transcription factor activity
HV234_RS04695	COG1349	DNA-binding transcription factor activity
HV234_RS04710	COG1312	Catalyzes the dehydration of D-mannonate
HV234_RS04715	COG3104	oligopeptide transport
HV234_RS04725	COG2909	trisaccharide binding
HV234_RS04730	COG1538	Outer membrane efflux protein
HV234_RS04735	COG1289	transmembrane transporter activity
HV234_RS04750	COG3592	Divergent 4Fe-4S mono-cluster
HV234_RS04755	COG2388	GCN5-related N-acetyl-transferase
HV234_RS04765	COG3539	Fimbrial protein
HV234_RS04770	COG3539	Fimbrial protein
HV234_RS04775	COG3539	Fimbrial protein
HV234_RS04780	COG3188	usher protein
HV234_RS04785	COG3121	Chaperone
HV234_RS04790	COG3539	Fimbrial protein
HV234_RS04800	COG4974	Belongs to the 'phage' integrase family
HV234_RS04805	COG0582	viral genome integration into host DNA
HV234_RS04815	COG1522	sequence-specific DNA binding
HV234_RS04820	COG1846	Transcriptional regulator
HV234_RS04825	COG0697	spore germination
HV234_RS04840	COG0640	Transcriptional regulator
HV234_RS04885	COG0667	Aldo Keto reductase
HV234_RS04890	COG0814	amino acid
HV234_RS04905	COG0183	Belongs to the thiolase family
HV234_RS04915	COG0823	Involved in the tonB-independent uptake of proteins
HV234_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS04925	COG2814	Major facilitator Superfamily
HV234_RS04950	COG0823	Involved in the tonB-independent uptake of proteins
HV234_RS04960	COG3842	ATPase activity
HV234_RS04965	COG0395	ABC-type sugar transport system, permease component
HV234_RS04970	COG1175	transmembrane transport
HV234_RS04980	COG1794	racemase activity, acting on amino acids and derivatives
HV234_RS04985	COG0583	DNA-binding transcription factor activity
HV234_RS04995	COG1609	Transcriptional regulator
HV234_RS05000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV234_RS05005	COG2723	6-phospho-beta-galactosidase activity
HV234_RS05010	COG2186	Transcriptional regulator
HV234_RS05020	COG1609	Transcriptional regulator
HV234_RS05035	COG0667	Aldo Keto reductase
HV234_RS05045	COG0861	Integral membrane protein TerC family
HV234_RS05080	COG2165	general secretion pathway protein
HV234_RS05085	COG4795	General secretion pathway protein
HV234_RS05095	COG4967	type IV pilus modification protein PilV
HV234_RS05100	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HV234_RS05105	COG1025	Belongs to the peptidase M16 family
HV234_RS05110	COG1074	ATP-dependent DNA helicase activity
HV234_RS05115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HV234_RS05120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HV234_RS05120	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HV234_RS05125	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV234_RS05130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HV234_RS05160	COG4656	Part of a membrane complex involved in electron transport
HV234_RS05165	COG1454	alcohol dehydrogenase
HV234_RS05195	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HV234_RS05360	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HV234_RS05365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HV234_RS05370	COG2166	iron-sulfur cluster assembly
HV234_RS05375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HV234_RS05385	COG0583	DNA-binding transcription factor activity
HV234_RS05390	COG2363	Small membrane protein
HV234_RS05400	COG1349	DNA-binding transcription factor activity
HV234_RS05420	COG0738	Major facilitator superfamily
HV234_RS05425	COG0235	Class ii aldolase
HV234_RS05440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV234_RS05455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV234_RS05460	COG1760	l-serine dehydratase
HV234_RS05465	COG0814	amino acid
HV234_RS05470	COG1611	Belongs to the LOG family
HV234_RS05490	COG3098	single-species biofilm formation
HV234_RS05495	COG0564	pseudouridine synthase activity
HV234_RS05500	COG0716	FMN binding
HV234_RS05505	COG2271	Major facilitator Superfamily
HV234_RS05510	COG4948	Mandelate Racemase Muconate Lactonizing
HV234_RS05515	COG4948	Mandelate Racemase Muconate Lactonizing
HV234_RS05520	COG1929	Belongs to the glycerate kinase type-1 family
HV234_RS05525	COG3850	Histidine kinase
HV234_RS05525	COG2205	protein histidine kinase activity
HV234_RS05525	COG3437	response regulator, receiver
HV234_RS05525	COG4999	Histidine kinase
HV234_RS05535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV234_RS05540	COG3956	TIGRFAM MazG family protein
HV234_RS05560	COG0602	queuosine metabolic process
HV234_RS05565	COG0720	synthase
HV234_RS05590	COG2234	aminopeptidase activity
HV234_RS05650	COG4942	peptidase
HV234_RS05650	COG1388	LysM domain
HV234_RS05655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HV234_RS05685	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV234_RS05705	COG3539	Fimbrial protein
HV234_RS05715	COG3188	usher protein
HV234_RS05720	COG3121	Chaperone
HV234_RS05730	COG3539	Fimbrial protein
HV234_RS05735	COG3539	Fimbrial protein
HV234_RS05760	COG1132	(ABC) transporter
HV234_RS05765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV234_RS05775	COG1538	Outer membrane efflux protein
HV234_RS05780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV234_RS05820	COG1454	alcohol dehydrogenase
HV234_RS05825	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HV234_RS05830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV234_RS05835	COG4558	Periplasmic binding protein
HV234_RS05840	COG3720	iron ion transport
HV234_RS05860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV234_RS05865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV234_RS05870	COG1121	(ABC) transporter
HV234_RS05880	COG1609	Transcriptional regulator
HV234_RS05885	COG1940	carbohydrate kinase activity
HV234_RS05890	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV234_RS05895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV234_RS05900	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV234_RS05905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV234_RS05920	COG2723	6-phospho-beta-galactosidase activity
HV234_RS05925	COG2755	lipolytic protein G-D-S-L family
HV234_RS05925	COG0657	acetylesterase activity
HV234_RS05935	COG0309	Hydrogenase expression formation protein (HypE)
HV234_RS05940	COG0409	Hydrogenase expression formation protein
HV234_RS05945	COG0298	carbon dioxide binding
HV234_RS05950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HV234_RS05965	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV234_RS05970	COG0651	ATP synthesis coupled electron transport
HV234_RS05975	COG0650	Formate hydrogenlyase subunit 4
HV234_RS05980	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HV234_RS05980	COG3261	NADH dehydrogenase
HV234_RS05985	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV234_RS05990	COG3260	NADH ubiquinone oxidoreductase 20
HV234_RS06000	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HV234_RS06005	COG2723	6-phospho-beta-galactosidase activity
HV234_RS06010	COG1263	PTS System
HV234_RS06010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV234_RS06015	COG1609	Transcriptional regulator
HV234_RS06020	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV234_RS06025	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HV234_RS06030	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HV234_RS06055	COG1349	DNA-binding transcription factor activity
HV234_RS06060	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS06065	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS06075	COG3732	PTS system glucitol sorbitol-specific
HV234_RS06080	COG3730	PTS system glucitol sorbitol-specific
HV234_RS06085	COG2951	lytic endotransglycosylase activity
HV234_RS06095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV234_RS06100	COG0803	Belongs to the bacterial solute-binding protein 9 family
HV234_RS06105	COG1546	Belongs to the CinA family
HV234_RS06125	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HV234_RS06155	COG2823	Periplasmic or secreted lipoprotein
HV234_RS06160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV234_RS06165	COG1238	metal cluster binding
HV234_RS06185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HV234_RS06190	COG2814	Major facilitator Superfamily
HV234_RS06195	COG1566	PFAM secretion protein HlyD family protein
HV234_RS06200	COG1846	Transcriptional regulator
HV234_RS06210	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV234_RS06215	COG2113	Glycine betaine
HV234_RS06220	COG4176	ABC-type proline glycine betaine transport system permease component
HV234_RS06230	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV234_RS06235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV234_RS06245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV234_RS06250	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV234_RS06260	COG4575	ribosome binding
HV234_RS06285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV234_RS06290	COG0640	Transcriptional regulator
HV234_RS06295	COG3284	Transcriptional regulator
HV234_RS06300	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS06315	COG3188	usher protein
HV234_RS06340	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS06345	COG2814	Major facilitator Superfamily
HV234_RS06360	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS06370	COG0235	Class ii aldolase
HV234_RS06375	COG1126	abc transporter atp-binding protein
HV234_RS06380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV234_RS06445	COG4974	Belongs to the 'phage' integrase family
HV234_RS06545	COG0582	viral genome integration into host DNA
HV234_RS06560	COG2867	negative regulation of translational initiation
HV234_RS06575	COG0497	DNA recombination
HV234_RS06590	COG4536	flavin adenine dinucleotide binding
HV234_RS06595	COG4137	Cytochrome C assembly protein
HV234_RS06600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HV234_RS06635	COG2885	chlorophyll binding
HV234_RS06640	COG2199	diguanylate cyclase activity
HV234_RS06650	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV234_RS06655	COG1605	Chorismate mutase
HV234_RS06655	COG0287	Prephenate dehydrogenase
HV234_RS06665	COG1605	Chorismate mutase
HV234_RS06665	COG0077	Prephenate dehydratase
HV234_RS06670	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV234_RS06675	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV234_RS06690	COG0542	response to heat
HV234_RS06715	COG0477	Major facilitator Superfamily
HV234_RS06720	COG5544	Lipoprotein
HV234_RS06725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV234_RS06740	COG3118	belongs to the thioredoxin family
HV234_RS06745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV234_RS06760	COG0513	Belongs to the DEAD box helicase family
HV234_RS06770	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HV234_RS06785	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HV234_RS06795	COG3086	response to oxidative stress
HV234_RS06805	COG0681	Belongs to the peptidase S26 family
HV234_RS06825	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HV234_RS06835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV234_RS06840	COG1737	Transcriptional regulator
HV234_RS06845	COG0560	Phosphoserine phosphatase
HV234_RS06860	COG0047	phosphoribosylformylglycinamidine synthase activity
HV234_RS06860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HV234_RS06865	COG2205	protein histidine kinase activity
HV234_RS06870	COG3170	Tfp pilus assembly protein FimV
HV234_RS06875	COG2204	response regulator
HV234_RS06880	COG0347	Belongs to the P(II) protein family
HV234_RS06895	COG2259	Doxx family
HV234_RS06900	COG1940	carbohydrate kinase activity
HV234_RS06905	COG0457	Tetratricopeptide repeat
HV234_RS06910	COG0477	Major facilitator Superfamily
HV234_RS06910	COG2814	Major facilitator Superfamily
HV234_RS06915	COG2017	converts alpha-aldose to the beta-anomer
HV234_RS06920	COG2814	Major facilitator Superfamily
HV234_RS06925	COG3711	transcriptional antiterminator
HV234_RS06930	COG3683	transport system, periplasmic component
HV234_RS06935	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HV234_RS06960	COG0822	iron-sulfur transferase activity
HV234_RS06980	COG0633	Ferredoxin
HV234_RS06985	COG2975	iron-sulfur cluster assembly
HV234_RS07000	COG2897	thiosulfate sulfurtransferase activity
HV234_RS07005	COG2373	Large extracellular alpha-helical protein
HV234_RS07010	COG4953	penicillin-binding protein 1C
HV234_RS07040	COG2976	Protein conserved in bacteria
HV234_RS07065	COG1645	bacterial-type flagellum-dependent swarming motility
HV234_RS07080	COG1570	exodeoxyribonuclease VII activity
HV234_RS07085	COG0517	IMP dehydrogenase activity
HV234_RS07085	COG0516	GMP reductase activity
HV234_RS07090	COG0519	Catalyzes the synthesis of GMP from XMP
HV234_RS07090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HV234_RS07125	COG3723	Recombinational DNA repair protein, rece pathway
HV234_RS07245	COG3728	DNA packaging
HV234_RS07245	COG5484	DNA packaging
HV234_RS07345	COG3617	BRO family, N-terminal domain
HV234_RS07385	COG3179	chitinase
HV234_RS07400	COG0583	DNA-binding transcription factor activity
HV234_RS07410	COG2200	EAL domain
HV234_RS07415	COG0248	Ppx GppA phosphatase
HV234_RS07445	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HV234_RS07460	COG2723	6-phospho-beta-galactosidase activity
HV234_RS07465	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HV234_RS07470	COG2233	PERMEase
HV234_RS07480	COG1393	Belongs to the ArsC family
HV234_RS07485	COG4783	chaperone-mediated protein folding
HV234_RS07490	COG0628	permease
HV234_RS07495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HV234_RS07500	COG2716	regulation of RNA biosynthetic process
HV234_RS07510	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HV234_RS07520	COG2321	neutral zinc metallopeptidase
HV234_RS07530	COG0400	carboxylic ester hydrolase activity
HV234_RS07545	COG1393	Belongs to the ArsC family
HV234_RS07555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV234_RS07560	COG0493	'glutamate synthase
HV234_RS07560	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV234_RS07570	COG5342	invasion associated locus B
HV234_RS07575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV234_RS07585	COG4810	utilization protein
HV234_RS07595	COG4766	ethanolamine catabolic process
HV234_RS07665	COG2207	Transcriptional regulator
HV234_RS07675	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV234_RS07695	COG2837	iron assimilation
HV234_RS07700	COG4150	thiosulfate binding
HV234_RS07705	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HV234_RS07710	COG4208	sulfate ABC transporter
HV234_RS07715	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HV234_RS07725	COG4319	ketosteroid isomerase
HV234_RS07765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HV234_RS07785	COG3530	Putative quorum-sensing-regulated virulence factor
HV234_RS07790	COG0385	Bile acid
HV234_RS07795	COG0583	DNA-binding transcription factor activity
HV234_RS07800	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HV234_RS07805	COG2211	Major facilitator Superfamily
HV234_RS07810	COG0583	DNA-binding transcription factor activity
HV234_RS07840	COG3415	Transposase
HV234_RS07845	COG3415	Transposase
HV234_RS07875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV234_RS07890	COG0667	Aldo Keto reductase
HV234_RS07895	COG3961	Belongs to the TPP enzyme family
HV234_RS07910	COG3279	Response regulator of the LytR AlgR family
HV234_RS07915	COG3275	phosphorelay sensor kinase activity
HV234_RS07920	COG0436	Aminotransferase
HV234_RS07940	COG0582	viral genome integration into host DNA
HV234_RS08045	COG3179	chitinase
HV234_RS08080	COG1802	Transcriptional regulator
HV234_RS08080	COG4626	Terminase
HV234_RS08085	COG4695	Portal protein
HV234_RS08090	COG0740	serine-type endopeptidase activity
HV234_RS08150	COG3039	Transposase
HV234_RS08205	COG2116	formate transmembrane transporter activity
HV234_RS08220	COG3691	Protein conserved in bacteria
HV234_RS08235	COG2062	phosphohistidine phosphatase, SixA
HV234_RS08260	COG0730	response to heat
HV234_RS08265	COG3101	peptidyl-lysine hydroxylation
HV234_RS08280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV234_RS08300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV234_RS08310	COG0586	Pfam SNARE associated Golgi protein
HV234_RS08320	COG0285	dihydrofolate synthase activity
HV234_RS08325	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HV234_RS08330	COG1286	toxin biosynthetic process
HV234_RS08335	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HV234_RS08340	COG0163	prenyltransferase activity
HV234_RS08360	COG4160	amino acid transport
HV234_RS08365	COG4598	ABC transporter
HV234_RS08385	COG1090	epimerase
HV234_RS08390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV234_RS08395	COG0625	glutathione transferase activity
HV234_RS08400	COG0625	glutathione transferase activity
HV234_RS08405	COG0622	Phosphoesterase
HV234_RS08415	COG1609	Transcriptional regulator
HV234_RS08420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS08430	COG3037	sugar-specific permease SgaT UlaA
HV234_RS08435	COG3959	Transketolase, thiamine diphosphate binding domain
HV234_RS08440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HV234_RS08465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV234_RS08470	COG0490	domain, Protein
HV234_RS08470	COG0471	metal ion transport
HV234_RS08480	COG0436	Aminotransferase
HV234_RS08485	COG0583	DNA-binding transcription factor activity
HV234_RS08530	COG0839	Belongs to the complex I subunit 6 family
HV234_RS08535	COG0713	ATP synthesis coupled electron transport
HV234_RS08540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HV234_RS08545	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV234_RS08555	COG0582	viral genome integration into host DNA
HV234_RS08585	COG0582	viral genome integration into host DNA
HV234_RS08595	COG2153	protein acetylation
HV234_RS08600	COG1169	isochorismate synthase
HV234_RS08630	COG3647	Membrane
HV234_RS08655	COG0642	Histidine kinase
HV234_RS08685	COG1414	Transcriptional regulator
HV234_RS08695	COG2271	Major facilitator Superfamily
HV234_RS08705	COG0247	lactate metabolic process
HV234_RS08715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV234_RS08720	COG2271	Major facilitator Superfamily
HV234_RS08725	COG0584	glycerophosphoryl diester phosphodiesterase
HV234_RS08730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV234_RS08755	COG0784	Response regulator, receiver
HV234_RS08755	COG2205	protein histidine kinase activity
HV234_RS08765	COG2198	Histidine kinase
HV234_RS08765	COG0642	Histidine kinase
HV234_RS08780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HV234_RS08780	COG2169	Transcriptional regulator
HV234_RS08790	COG4615	Cyclic peptide transporter
HV234_RS08795	COG2239	Acts as a magnesium transporter
HV234_RS08800	COG0659	secondary active sulfate transmembrane transporter activity
HV234_RS08820	COG0628	permease
HV234_RS08845	COG1349	DNA-binding transcription factor activity
HV234_RS08850	COG0494	nUDIX hydrolase
HV234_RS08860	COG1061	Type III restriction enzyme res subunit
HV234_RS08865	COG1187	pseudouridine synthase activity
HV234_RS08870	COG2814	Major facilitator Superfamily
HV234_RS08880	COG4172	Belongs to the ABC transporter superfamily
HV234_RS08885	COG4239	(ABC) transporter, permease
HV234_RS08890	COG4174	ABC transporter (Permease)
HV234_RS08895	COG4166	transmembrane transport
HV234_RS08900	COG2200	EAL domain
HV234_RS08905	COG0791	NLP P60 protein
HV234_RS08910	COG0671	phosphoesterase, PA-phosphatase related
HV234_RS08915	COG0523	cobalamin synthesis protein
HV234_RS08920	COG0246	Mannitol dehydrogenase
HV234_RS08925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HV234_RS08935	COG2814	Major facilitator Superfamily
HV234_RS08940	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS08940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS08945	COG1105	Belongs to the carbohydrate kinase PfkB family
HV234_RS08950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV234_RS08950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV234_RS08950	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HV234_RS08955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV234_RS08960	COG2313	pseudouridylate synthase activity
HV234_RS08965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV234_RS08970	COG1522	sequence-specific DNA binding
HV234_RS08970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV234_RS08980	COG2855	membrane
HV234_RS08985	COG0583	DNA-binding transcription factor activity
HV234_RS08990	COG0833	amino acid
HV234_RS08995	COG4771	TonB-dependent receptor
HV234_RS09010	COG2311	Membrane
HV234_RS09025	COG1129	ABC transporter
HV234_RS09050	COG2949	membrane
HV234_RS09060	COG1346	cytolysis
HV234_RS09070	COG0583	DNA-binding transcription factor activity
HV234_RS09075	COG2271	Major facilitator Superfamily
HV234_RS09090	COG0625	glutathione transferase activity
HV234_RS09095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV234_RS09100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV234_RS09105	COG3711	transcriptional antiterminator
HV234_RS09115	COG2723	6-phospho-beta-galactosidase activity
HV234_RS09120	COG2226	methyltransferase
HV234_RS09125	COG1538	Outer membrane efflux protein
HV234_RS09130	COG0586	Pfam SNARE associated Golgi protein
HV234_RS09140	COG1686	Belongs to the peptidase S11 family
HV234_RS09150	COG0277	FAD linked oxidase domain protein
HV234_RS09155	COG1472	Belongs to the glycosyl hydrolase 3 family
HV234_RS09160	COG1732	Glycine betaine
HV234_RS09165	COG1174	glycine betaine transport
HV234_RS09170	COG1125	glycine betaine transport
HV234_RS09175	COG1174	glycine betaine transport
HV234_RS09185	COG0789	Transcriptional regulator
HV234_RS09190	COG3275	phosphorelay sensor kinase activity
HV234_RS09200	COG4807	Protein conserved in bacteria
HV234_RS09205	COG4808	Protein conserved in bacteria
HV234_RS09210	COG4715	Zinc finger, swim domain protein
HV234_RS09215	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HV234_RS09220	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HV234_RS09225	COG0714	Associated with various cellular activities
HV234_RS09230	COG3831	ATPase activity
HV234_RS09235	COG3831	ATPase activity
HV234_RS09245	COG0489	protein tyrosine kinase activity
HV234_RS09255	COG5455	response to cobalt ion
HV234_RS09260	COG0583	DNA-binding transcription factor activity
HV234_RS09265	COG2252	PERMEase
HV234_RS09275	COG0583	DNA-binding transcription factor activity
HV234_RS09280	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HV234_RS09290	COG0351	phosphomethylpyrimidine kinase
HV234_RS09295	COG1830	Aldolase
HV234_RS09325	COG1070	Carbohydrate kinase
HV234_RS09335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV234_RS09340	COG4948	Mandelate Racemase Muconate Lactonizing
HV234_RS09345	COG0747	negative chemotaxis
HV234_RS09350	COG0601	transmembrane transport
HV234_RS09360	COG0444	Belongs to the ABC transporter superfamily
HV234_RS09365	COG4608	Belongs to the ABC transporter superfamily
HV234_RS09390	COG0745	RESPONSE REGULATOR receiver
HV234_RS09395	COG2205	protein histidine kinase activity
HV234_RS09425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV234_RS09440	COG1522	sequence-specific DNA binding
HV234_RS09450	COG2267	carboxylic ester hydrolase activity
HV234_RS09465	COG0601	transmembrane transport
HV234_RS09470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV234_RS09475	COG0444	Belongs to the ABC transporter superfamily
HV234_RS09480	COG4608	Belongs to the ABC transporter superfamily
HV234_RS09490	COG1301	dicarboxylic acid transport
HV234_RS09510	COG5002	protein histidine kinase activity
HV234_RS09515	COG0243	molybdopterin cofactor binding
HV234_RS09515	COG3383	formate dehydrogenase (NAD+) activity
HV234_RS09520	COG0437	4 iron, 4 sulfur cluster binding
HV234_RS09525	COG2864	formate dehydrogenase
HV234_RS09530	COG0372	Belongs to the citrate synthase family
HV234_RS09535	COG0443	Heat shock 70 kDa protein
HV234_RS09540	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HV234_RS09555	COG2982	Protein involved in outer membrane biogenesis
HV234_RS09560	COG1253	flavin adenine dinucleotide binding
HV234_RS09595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HV234_RS09625	COG0110	maltose O-acetyltransferase activity
HV234_RS09640	COG1088	dTDP-glucose 4,6-dehydratase activity
HV234_RS09650	COG1091	dTDP-4-dehydrorhamnose reductase activity
HV234_RS09715	COG0463	Glycosyl transferase, family 2
HV234_RS09725	COG0107	imidazoleglycerol-phosphate synthase activity
HV234_RS09735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HV234_RS09750	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HV234_RS09765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV234_RS09770	COG0583	DNA-binding transcription factor activity
HV234_RS09780	COG0531	amino acid
HV234_RS09800	COG2205	protein histidine kinase activity
HV234_RS09885	COG0640	Transcriptional regulator
HV234_RS09890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HV234_RS09895	COG2925	Exonuclease
HV234_RS09915	COG1289	transmembrane transporter activity
HV234_RS09935	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HV234_RS09945	COG1942	4-Oxalocrotonate Tautomerase
HV234_RS09950	COG0583	DNA-binding transcription factor activity
HV234_RS09955	COG0095	Lipoate-protein ligase
HV234_RS09960	COG0477	Major facilitator Superfamily
HV234_RS09970	COG5001	Diguanylate cyclase
HV234_RS09970	COG3300	MHYT domain
HV234_RS09975	COG3615	Tellurite resistance protein tehB
HV234_RS09985	COG2188	Transcriptional regulator
HV234_RS09990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV234_RS09990	COG1263	PTS System
HV234_RS10005	COG3539	Fimbrial protein
HV234_RS10010	COG3539	Fimbrial protein
HV234_RS10015	COG3539	Fimbrial protein
HV234_RS10020	COG3188	usher protein
HV234_RS10025	COG3121	Chaperone
HV234_RS10030	COG3539	Fimbrial protein
HV234_RS10040	COG2197	response regulator
HV234_RS10050	COG3311	Transcriptional regulator
HV234_RS10190	COG0582	viral genome integration into host DNA
HV234_RS10200	COG0534	Mate efflux family protein
HV234_RS10210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HV234_RS10240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV234_RS10250	COG0589	response to stress
HV234_RS10260	COG2819	hydrolase of the alpha beta superfamily
HV234_RS10280	COG0251	oxidation-reduction process
HV234_RS10310	COG0463	Glycosyl transferase, family 2
HV234_RS10320	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV234_RS10330	COG1418	mRNA catabolic process
HV234_RS10335	COG0270	DNA (cytosine-5-)-methyltransferase activity
HV234_RS10340	COG3727	T/G mismatch-specific endonuclease activity
HV234_RS10345	COG0697	spore germination
HV234_RS10350	COG2354	Protein conserved in bacteria
HV234_RS10355	COG5475	Uncharacterized small protein (DUF2158)
HV234_RS10385	COG0366	Alpha amylase catalytic
HV234_RS10410	COG2197	response regulator
HV234_RS10420	COG2197	response regulator
HV234_RS10450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV234_RS10455	COG3318	Belongs to the UPF0149 family
HV234_RS10455	COG3012	SEC-C Motif Domain Protein
HV234_RS10460	COG0814	amino acid
HV234_RS10470	COG1528	Iron-storage protein
HV234_RS10480	COG0477	Major facilitator Superfamily
HV234_RS10500	COG1528	Iron-storage protein
HV234_RS10510	COG1879	ABC-type sugar transport system periplasmic component
HV234_RS10520	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS10550	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV234_RS10560	COG3102	Protein conserved in bacteria
HV234_RS10580	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HV234_RS10585	COG1801	Protein of unknown function DUF72
HV234_RS10590	COG0582	viral genome integration into host DNA
HV234_RS10790	COG5410	chromosome segregation
HV234_RS10870	COG1196	nuclear chromosome segregation
HV234_RS10870	COG0741	lytic transglycosylase activity
HV234_RS10870	COG0739	heme binding
HV234_RS10955	COG1335	isochorismatase
HV234_RS10965	COG0494	nUDIX hydrolase
HV234_RS10970	COG0217	transcriptional regulatory protein
HV234_RS10990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV234_RS11000	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HV234_RS11005	COG0739	heme binding
HV234_RS11010	COG1560	Kdo2-lipid A biosynthetic process
HV234_RS11020	COG1737	Transcriptional regulator
HV234_RS11025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HV234_RS11030	COG0129	dihydroxy-acid dehydratase activity
HV234_RS11035	COG0800	Aldolase
HV234_RS11045	COG3141	response to X-ray
HV234_RS11050	COG2979	Protein of unknown function (DUF533)
HV234_RS11055	COG1770	oligopeptidase
HV234_RS11060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV234_RS11070	COG2372	response to copper ion
HV234_RS11075	COG1276	copper resistance
HV234_RS11115	COG2990	Protein conserved in bacteria
HV234_RS11120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HV234_RS11140	COG3008	intermembrane lipid transfer
HV234_RS11145	COG2995	paraquat-inducible protein a
HV234_RS11150	COG1956	GAF domain-containing protein
HV234_RS11170	COG2814	Major facilitator Superfamily
HV234_RS11175	COG1414	Transcriptional regulator
HV234_RS11205	COG0768	penicillin binding
HV234_RS11210	COG2226	methyltransferase
HV234_RS11225	COG3716	PTS system mannose fructose sorbose family IID component
HV234_RS11230	COG3715	PTS system
HV234_RS11235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV234_RS11235	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS11240	COG1253	flavin adenine dinucleotide binding
HV234_RS11245	COG2200	EAL domain
HV234_RS11250	COG1760	l-serine dehydratase
HV234_RS11280	COG1653	transport
HV234_RS11285	COG1175	transmembrane transport
HV234_RS11290	COG0395	ABC-type sugar transport system, permease component
HV234_RS11295	COG3842	ATPase activity
HV234_RS11305	COG0251	oxidation-reduction process
HV234_RS11310	COG1199	ATP-dependent helicase activity
HV234_RS11315	COG1214	PFAM Peptidase M22, glycoprotease
HV234_RS11320	COG3065	identical protein binding
HV234_RS11330	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HV234_RS11340	COG2894	cell division
HV234_RS11355	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV234_RS11385	COG2719	SpoVR family
HV234_RS11405	COG1619	proteins homologs of microcin C7 resistance protein MccF
HV234_RS11425	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HV234_RS11430	COG2211	Major facilitator Superfamily
HV234_RS11440	COG1472	Belongs to the glycosyl hydrolase 3 family
HV234_RS11445	COG2308	Evidence 4 Homologs of previously reported genes of
HV234_RS11470	COG2814	Major facilitator Superfamily
HV234_RS11485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV234_RS11495	COG1174	glycine betaine transport
HV234_RS11510	COG0564	pseudouridine synthase activity
HV234_RS11515	COG0583	DNA-binding transcription factor activity
HV234_RS11535	COG2351	hydroxyisourate hydrolase activity
HV234_RS11540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS11540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS11545	COG2814	Major facilitator Superfamily
HV234_RS11560	COG2068	MobA-Related Protein
HV234_RS11570	COG2233	PERMEase
HV234_RS11580	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV234_RS11585	COG0402	S-adenosylhomocysteine deaminase activity
HV234_RS11590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV234_RS11590	COG0493	'glutamate synthase
HV234_RS11595	COG3608	succinylglutamate desuccinylase aspartoacylase
HV234_RS11595	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HV234_RS11600	COG0549	Belongs to the carbamate kinase family
HV234_RS11610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV234_RS11615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV234_RS11620	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HV234_RS11630	COG0012	GTP binding
HV234_RS11650	COG0659	secondary active sulfate transmembrane transporter activity
HV234_RS11680	COG2890	protein-(glutamine-N5) methyltransferase activity
HV234_RS11700	COG0387	Pfam Sodium calcium exchanger
HV234_RS11705	COG4572	Cation transport regulator
HV234_RS11710	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HV234_RS11720	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HV234_RS11725	COG3707	response regulator
HV234_RS11730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV234_RS11740	COG1116	anion transmembrane transporter activity
HV234_RS11745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV234_RS11745	COG2146	nitrite reductase [NAD(P)H] activity
HV234_RS11750	COG0243	molybdopterin cofactor binding
HV234_RS11755	COG4932	domain protein
HV234_RS11760	COG2197	response regulator
HV234_RS11765	COG3850	Histidine kinase
HV234_RS11770	COG2223	nitrite transmembrane transporter activity
HV234_RS11775	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV234_RS11780	COG1140	nitrate reductase beta subunit
HV234_RS11785	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV234_RS11790	COG2181	nitrate reductase activity
HV234_RS11800	COG1522	sequence-specific DNA binding
HV234_RS11820	COG0788	formyltetrahydrofolate deformylase activity
HV234_RS11830	COG1752	Esterase of the alpha-beta hydrolase superfamily
HV234_RS11835	COG0745	RESPONSE REGULATOR receiver
HV234_RS11840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HV234_RS11855	COG1454	alcohol dehydrogenase
HV234_RS11855	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS11860	COG2095	MarC family integral membrane protein
HV234_RS11870	COG0601	transmembrane transport
HV234_RS11875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV234_RS11880	COG0444	Belongs to the ABC transporter superfamily
HV234_RS11890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV234_RS11910	COG2350	Protein conserved in bacteria
HV234_RS11960	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HV234_RS11965	COG3001	Fructosamine kinase
HV234_RS11975	COG1105	Belongs to the carbohydrate kinase PfkB family
HV234_RS11980	COG3137	Salt-induced outer membrane protein
HV234_RS12005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HV234_RS12020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HV234_RS12020	COG0072	phenylalanine-tRNA ligase activity
HV234_RS12040	COG0386	Belongs to the glutathione peroxidase family
HV234_RS12050	COG0791	NLP P60 protein
HV234_RS12060	COG4256	Hemin uptake protein
HV234_RS12065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV234_RS12075	COG0574	Belongs to the PEP-utilizing enzyme family
HV234_RS12075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV234_RS12085	COG0628	permease
HV234_RS12090	COG0277	FAD linked oxidase domain protein
HV234_RS12090	COG0247	lactate metabolic process
HV234_RS12095	COG2050	protein possibly involved in aromatic compounds catabolism
HV234_RS12100	COG3039	Transposase
HV234_RS12105	COG2261	transglycosylase associated protein
HV234_RS12110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV234_RS12125	COG3121	Chaperone
HV234_RS12145	COG0316	Belongs to the HesB IscA family
HV234_RS12150	COG0719	Fe-S assembly protein
HV234_RS12155	COG0396	ATPase activity
HV234_RS12160	COG0719	Fe-S assembly protein
HV234_RS12175	COG1376	ErfK ybiS ycfS ynhG family protein
HV234_RS12205	COG2271	Major facilitator Superfamily
HV234_RS12210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV234_RS12215	COG1414	Transcriptional regulator
HV234_RS12250	COG2814	Major facilitator Superfamily
HV234_RS12275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV234_RS12280	COG1960	acyl-CoA dehydrogenase activity
HV234_RS12295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV234_RS12300	COG1116	anion transmembrane transporter activity
HV234_RS12305	COG4774	siderophore transport
HV234_RS12315	COG1120	ATPase activity
HV234_RS12320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV234_RS12325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV234_RS12345	COG0765	amino acid transport
HV234_RS12350	COG1126	abc transporter atp-binding protein
HV234_RS12370	COG3383	formate dehydrogenase (NAD+) activity
HV234_RS12375	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV234_RS12385	COG1175	transmembrane transport
HV234_RS12390	COG3842	ATPase activity
HV234_RS12415	COG1278	Cold shock
HV234_RS12420	COG0626	cystathionine gamma-synthase activity
HV234_RS12425	COG1757	Na H antiporter
HV234_RS12445	COG4993	Dehydrogenase
HV234_RS12450	COG4608	Belongs to the ABC transporter superfamily
HV234_RS12490	COG0747	negative chemotaxis
HV234_RS12505	COG2011	ABC-type metal ion transport system permease component
HV234_RS12520	COG0346	lactoylglutathione lyase activity
HV234_RS12525	COG1349	DNA-binding transcription factor activity
HV234_RS12540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV234_RS12545	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS12550	COG3039	Transposase
HV234_RS12555	COG3111	PFAM Bacterial OB fold (BOF) protein
HV234_RS12565	COG4529	Protein conserved in bacteria
HV234_RS12585	COG3039	Transposase
HV234_RS12590	COG1546	Belongs to the CinA family
HV234_RS12600	COG0366	Alpha amylase catalytic
HV234_RS12605	COG1294	oxidase, subunit
HV234_RS12610	COG1271	oxidase subunit
HV234_RS12615	COG3546	catalase activity
HV234_RS12620	COG3685	Protein conserved in bacteria
HV234_RS12625	COG3685	Protein conserved in bacteria
HV234_RS12630	COG3729	General stress protein
HV234_RS12655	COG0307	riboflavin synthase, alpha
HV234_RS12660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV234_RS12665	COG2814	Major facilitator Superfamily
HV234_RS12670	COG0583	DNA-binding transcription factor activity
HV234_RS12685	COG2814	Major facilitator Superfamily
HV234_RS12690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HV234_RS12695	COG0791	NLP P60 protein
HV234_RS12700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HV234_RS12710	COG0346	lactoylglutathione lyase activity
HV234_RS12715	COG1902	pentaerythritol trinitrate reductase activity
HV234_RS12720	COG1309	transcriptional regulator
HV234_RS12725	COG3313	Fe-S protein
HV234_RS12730	COG4989	oxidoreductase activity
HV234_RS12740	COG1289	transmembrane transporter activity
HV234_RS12745	COG1566	PFAM secretion protein HlyD family protein
HV234_RS12760	COG3706	GGDEF domain
HV234_RS12775	COG3895	Periplasmic Protein
HV234_RS12795	COG0625	glutathione transferase activity
HV234_RS12805	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HV234_RS12815	COG4659	FMN binding
HV234_RS12855	COG2723	6-phospho-beta-galactosidase activity
HV234_RS12865	COG0673	inositol 2-dehydrogenase activity
HV234_RS12880	COG0425	Belongs to the sulfur carrier protein TusA family
HV234_RS12885	COG2391	methyltransferase activity
HV234_RS12895	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV234_RS12900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV234_RS12900	COG1263	PTS System
HV234_RS12905	COG1609	Transcriptional regulator
HV234_RS12910	COG5339	Protein conserved in bacteria
HV234_RS12920	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV234_RS12920	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV234_RS12925	COG0114	fumarate hydratase activity
HV234_RS12935	COG2205	protein histidine kinase activity
HV234_RS12945	COG0745	RESPONSE REGULATOR receiver
HV234_RS12955	COG3136	membrane protein required for alginate biosynthesis
HV234_RS12965	COG0531	amino acid
HV234_RS12980	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HV234_RS12985	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HV234_RS12995	COG0589	response to stress
HV234_RS13000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV234_RS13010	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HV234_RS13015	COG1473	amidohydrolase
HV234_RS13025	COG0583	DNA-binding transcription factor activity
HV234_RS13030	COG2840	Smr protein MutS2
HV234_RS13035	COG1414	Transcriptional regulator
HV234_RS13045	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HV234_RS13050	COG0183	Belongs to the thiolase family
HV234_RS13060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HV234_RS13065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV234_RS13070	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV234_RS13070	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV234_RS13090	COG4565	transcriptional regulatory protein
HV234_RS13095	COG3290	protein histidine kinase activity
HV234_RS13105	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS13110	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HV234_RS13125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HV234_RS13135	COG0679	Auxin Efflux Carrier
HV234_RS13165	COG0628	permease
HV234_RS13185	COG3591	Belongs to the peptidase S1B family
HV234_RS13200	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HV234_RS13205	COG2814	Major facilitator Superfamily
HV234_RS13210	COG0583	DNA-binding transcription factor activity
HV234_RS13215	COG1940	carbohydrate kinase activity
HV234_RS13220	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HV234_RS13235	COG3302	dmso reductase anchor subunit
HV234_RS13240	COG0437	4 iron, 4 sulfur cluster binding
HV234_RS13245	COG0243	molybdopterin cofactor binding
HV234_RS13270	COG0243	molybdopterin cofactor binding
HV234_RS13285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV234_RS13300	COG4948	Mandelate Racemase Muconate Lactonizing
HV234_RS13305	COG1063	alcohol dehydrogenase
HV234_RS13310	COG0477	Major facilitator Superfamily
HV234_RS13315	COG0246	Mannitol dehydrogenase
HV234_RS13320	COG0589	response to stress
HV234_RS13325	COG1802	Transcriptional regulator
HV234_RS13330	COG4221	oxidoreductase activity
HV234_RS13335	COG0339	signal peptide processing
HV234_RS13350	COG3122	Protein conserved in bacteria
HV234_RS13375	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HV234_RS13380	COG2223	nitrite transmembrane transporter activity
HV234_RS13400	COG2200	EAL domain
HV234_RS13435	COG3210	domain, Protein
HV234_RS13465	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HV234_RS13485	COG1129	ABC transporter
HV234_RS13500	COG2814	Major facilitator Superfamily
HV234_RS13505	COG0697	spore germination
HV234_RS13550	COG2731	YhcH YjgK YiaL family protein
HV234_RS13560	COG0861	Integral membrane protein TerC family
HV234_RS13565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV234_RS13570	COG1454	alcohol dehydrogenase
HV234_RS13575	COG3395	kinase activity
HV234_RS13580	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HV234_RS13585	COG1349	DNA-binding transcription factor activity
HV234_RS13590	COG0039	L-malate dehydrogenase activity
HV234_RS13600	COG0583	DNA-binding transcription factor activity
HV234_RS13605	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS13620	COG2199	diguanylate cyclase activity
HV234_RS13665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV234_RS13670	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV234_RS13695	COG2814	Major facilitator Superfamily
HV234_RS13720	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS13755	COG3039	Transposase
HV234_RS13765	COG0477	Major facilitator Superfamily
HV234_RS13780	COG2011	ABC-type metal ion transport system permease component
HV234_RS13800	COG4628	conserved protein (DUF2132)
HV234_RS13815	COG1126	abc transporter atp-binding protein
HV234_RS13820	COG0765	amino acid transport
HV234_RS13825	COG0765	amino acid transport
HV234_RS13845	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HV234_RS13850	COG2207	Transcriptional regulator
HV234_RS13860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HV234_RS13865	COG1446	asparaginase
HV234_RS13870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV234_RS13885	COG1120	ATPase activity
HV234_RS13890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV234_RS13895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV234_RS13925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV234_RS13930	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS13935	COG1070	Carbohydrate kinase
HV234_RS13965	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS13980	COG1609	Transcriptional regulator
HV234_RS13990	COG0693	protein deglycase activity
HV234_RS14005	COG0412	Dienelactone hydrolase
HV234_RS14010	COG0583	DNA-binding transcription factor activity
HV234_RS14035	COG2841	Protein conserved in bacteria
HV234_RS14060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS14075	COG4821	SIS domain
HV234_RS14080	COG2188	Transcriptional regulator
HV234_RS14120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HV234_RS14150	COG3539	Fimbrial protein
HV234_RS14155	COG3121	Chaperone
HV234_RS14160	COG3539	Fimbrial protein
HV234_RS14205	COG3391	amine dehydrogenase activity
HV234_RS14210	COG4771	TonB-dependent receptor
HV234_RS14220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV234_RS14235	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS14245	COG1609	Transcriptional regulator
HV234_RS14280	COG1652	LysM domain
HV234_RS14285	COG4771	TonB-dependent receptor
HV234_RS14290	COG1021	2,3-dihydroxybenzoate-AMP ligase
HV234_RS14310	COG3433	isochorismatase activity
HV234_RS14310	COG2226	methyltransferase
HV234_RS14310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HV234_RS14325	COG1132	(ABC) transporter
HV234_RS14330	COG2814	Major facilitator Superfamily
HV234_RS14335	COG1169	isochorismate synthase
HV234_RS14360	COG0814	amino acid
HV234_RS14365	COG1760	l-serine dehydratase
HV234_RS14395	COG2801	Transposase and inactivated derivatives
HV234_RS14405	COG2801	Transposase and inactivated derivatives
HV234_RS14415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HV234_RS14420	COG0022	dehydrogenase e1 component
HV234_RS14425	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV234_RS14430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV234_RS14445	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HV234_RS14450	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS14460	COG0401	homolog of Blt101
HV234_RS14470	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV234_RS14475	COG2771	luxR family
HV234_RS14475	COG2200	EAL domain
HV234_RS14520	COG1609	Transcriptional regulator
HV234_RS14525	COG1082	Xylose isomerase domain protein TIM barrel
HV234_RS14530	COG0673	inositol 2-dehydrogenase activity
HV234_RS14535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HV234_RS14540	COG1116	anion transmembrane transporter activity
HV234_RS14545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV234_RS14550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV234_RS14555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV234_RS14560	COG0076	glutamate decarboxylase activity
HV234_RS14575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HV234_RS14575	COG0519	Catalyzes the synthesis of GMP from XMP
HV234_RS14590	COG0439	Biotin carboxylase
HV234_RS14605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HV234_RS14630	COG1280	lysine exporter protein (LysE YggA)
HV234_RS14665	COG1285	pathogenesis
HV234_RS14675	COG2271	Major facilitator Superfamily
HV234_RS14685	COG0583	DNA-binding transcription factor activity
HV234_RS14690	COG0583	DNA-binding transcription factor activity
HV234_RS14700	COG1280	lysine exporter protein (LysE YggA)
HV234_RS14705	COG0243	molybdopterin cofactor binding
HV234_RS14710	COG3781	membrane
HV234_RS14725	COG1764	response to oxidative stress
HV234_RS14735	COG0583	DNA-binding transcription factor activity
HV234_RS14755	COG0488	(ABC) transporter
HV234_RS14770	COG1064	alcohol dehydrogenase
HV234_RS14800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV234_RS14810	COG2814	Major facilitator Superfamily
HV234_RS14820	COG2864	formate dehydrogenase
HV234_RS14825	COG0437	4 iron, 4 sulfur cluster binding
HV234_RS14835	COG0697	spore germination
HV234_RS14850	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HV234_RS14860	COG3485	protocatechuate 3,4-dioxygenase
HV234_RS14865	COG4829	muconolactone delta-isomerase
HV234_RS14870	COG4948	Mandelate Racemase Muconate Lactonizing
HV234_RS14875	COG1414	Transcriptional regulator
HV234_RS14890	COG2223	nitrite transmembrane transporter activity
HV234_RS14895	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV234_RS14900	COG1140	nitrate reductase beta subunit
HV234_RS14905	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV234_RS14910	COG2181	nitrate reductase activity
HV234_RS14915	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HV234_RS14920	COG1178	ABC-type Fe3 transport system permease component
HV234_RS14930	COG3842	ATPase activity
HV234_RS14935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV234_RS14955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV234_RS14980	COG4772	TonB-dependent receptor
HV234_RS14985	COG3691	Protein conserved in bacteria
HV234_RS14995	COG2130	NADP-dependent
HV234_RS15005	COG1247	-acetyltransferase
HV234_RS15010	COG3238	Protein conserved in bacteria
HV234_RS15020	COG0747	negative chemotaxis
HV234_RS15025	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS15030	COG4677	pectinesterase activity
HV234_RS15035	COG0596	Alpha beta hydrolase
HV234_RS15060	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS15065	COG1177	transmembrane transport
HV234_RS15070	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV234_RS15075	COG3842	ATPase activity
HV234_RS15080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV234_RS15085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV234_RS15090	COG1271	oxidase subunit
HV234_RS15095	COG1294	oxidase, subunit
HV234_RS15110	COG0826	peptidase U32
HV234_RS15115	COG1396	sequence-specific DNA binding
HV234_RS15125	COG3135	benzoate transporter
HV234_RS15130	COG3708	Transcriptional regulator
HV234_RS15130	COG2207	Transcriptional regulator
HV234_RS15135	COG0697	spore germination
HV234_RS15145	COG0747	negative chemotaxis
HV234_RS15150	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV234_RS15155	COG0500	methyltransferase
HV234_RS15160	COG1275	C4-dicarboxylate transporter malic acid transport protein
HV234_RS15165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV234_RS15170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV234_RS15180	COG1335	isochorismatase
HV234_RS15190	COG5383	Protein conserved in bacteria
HV234_RS15195	COG3485	protocatechuate 3,4-dioxygenase
HV234_RS15200	COG3485	protocatechuate 3,4-dioxygenase
HV234_RS15205	COG0583	DNA-binding transcription factor activity
HV234_RS15230	COG3038	cytochrome b561
HV234_RS15255	COG3706	GGDEF domain
HV234_RS15260	COG0583	DNA-binding transcription factor activity
HV234_RS15265	COG0456	acetyltransferase
HV234_RS15270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HV234_RS15275	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS15280	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV234_RS15285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HV234_RS15310	COG4122	O-methyltransferase activity
HV234_RS15315	COG1643	Atp-dependent helicase
HV234_RS15330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV234_RS15335	COG3327	negative regulation of DNA-templated transcription, initiation
HV234_RS15340	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HV234_RS15345	COG0183	Belongs to the thiolase family
HV234_RS15350	COG2050	protein possibly involved in aromatic compounds catabolism
HV234_RS15355	COG1250	3-hydroxyacyl-CoA dehydrogenase
HV234_RS15360	COG1024	Enoyl-CoA hydratase
HV234_RS15365	COG1024	Enoyl-CoA hydratase
HV234_RS15370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV234_RS15375	COG2151	metal-sulfur cluster biosynthetic enzyme
HV234_RS15380	COG3396	Phenylacetate-CoA oxygenase
HV234_RS15385	COG3460	Phenylacetate-CoA oxygenase
HV234_RS15390	COG3396	Phenylacetate-CoA oxygenase
HV234_RS15395	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS15395	COG2030	dehydratase
HV234_RS15410	COG3813	Protein conserved in bacteria
HV234_RS15415	COG0583	DNA-binding transcription factor activity
HV234_RS15430	COG1733	regulation of RNA biosynthetic process
HV234_RS15445	COG0477	Major facilitator Superfamily
HV234_RS15450	COG0582	viral genome integration into host DNA
HV234_RS15455	COG0406	alpha-ribazole phosphatase activity
HV234_RS15465	COG0583	DNA-binding transcription factor activity
HV234_RS15470	COG0583	DNA-binding transcription factor activity
HV234_RS15490	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HV234_RS15495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV234_RS15500	COG4977	sequence-specific DNA binding
HV234_RS15510	COG0477	Major facilitator Superfamily
HV234_RS15530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV234_RS15535	COG3708	Transcriptional regulator
HV234_RS15535	COG2207	Transcriptional regulator
HV234_RS15540	COG2207	Transcriptional regulator
HV234_RS15555	COG1566	PFAM secretion protein HlyD family protein
HV234_RS15585	COG2072	flavoprotein involved in K transport
HV234_RS15590	COG0583	DNA-binding transcription factor activity
HV234_RS15595	COG1126	abc transporter atp-binding protein
HV234_RS15600	COG5285	phytanoyl-CoA dioxygenase
HV234_RS15615	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS15620	COG2207	Transcriptional regulator
HV234_RS15625	COG3784	Protein of unknown function (DUF1318)
HV234_RS15635	COG2911	Protein conserved in bacteria
HV234_RS15645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HV234_RS15650	COG3187	Heat shock protein
HV234_RS15655	COG3042	response to heat
HV234_RS15700	COG0674	pyruvate-flavodoxin oxidoreductase activity
HV234_RS15700	COG1013	pyruvate-flavodoxin oxidoreductase activity
HV234_RS15700	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HV234_RS15700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV234_RS15705	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV234_RS15725	COG0513	Belongs to the DEAD box helicase family
HV234_RS15740	COG1349	DNA-binding transcription factor activity
HV234_RS15745	COG0673	inositol 2-dehydrogenase activity
HV234_RS15750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HV234_RS15775	COG3477	response to acidic pH
HV234_RS15780	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HV234_RS15780	COG2885	chlorophyll binding
HV234_RS15795	COG0583	DNA-binding transcription factor activity
HV234_RS15810	COG0583	DNA-binding transcription factor activity
HV234_RS15835	COG0789	Transcriptional regulator
HV234_RS15845	COG0300	oxidoreductase activity
HV234_RS15860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV234_RS15880	COG3272	Protein of unknown function (DUF1722)
HV234_RS15885	COG4580	involved in the transport of maltose and maltodextrins
HV234_RS15895	COG2211	Major facilitator Superfamily
HV234_RS15900	COG3507	Belongs to the glycosyl hydrolase 43 family
HV234_RS15935	COG3436	PFAM IS66 Orf2 family protein
HV234_RS15940	COG4372	Transposase
HV234_RS16030	COG0740	serine-type endopeptidase activity
HV234_RS16035	COG4695	Portal protein
HV234_RS16040	COG1802	Transcriptional regulator
HV234_RS16040	COG4626	Terminase
HV234_RS16110	COG1802	Transcriptional regulator
HV234_RS16110	COG4626	Terminase
HV234_RS16190	COG0582	viral genome integration into host DNA
HV234_RS16195	COG0693	protein deglycase activity
HV234_RS16200	COG4166	transmembrane transport
HV234_RS16205	COG2866	Carboxypeptidase
HV234_RS16210	COG4948	Mandelate Racemase Muconate Lactonizing
HV234_RS16215	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HV234_RS16220	COG3180	Ammonia monooxygenase
HV234_RS16235	COG3106	COG3106 Predicted ATPase
HV234_RS16240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV234_RS16250	COG1983	PspC domain protein
HV234_RS16260	COG1842	Phage shock protein A
HV234_RS16265	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV234_RS16275	COG1473	amidohydrolase
HV234_RS16290	COG4166	transmembrane transport
HV234_RS16300	COG4171	peptide transport system, permease
HV234_RS16310	COG4172	Belongs to the ABC transporter superfamily
HV234_RS16320	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HV234_RS16325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV234_RS16325	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV234_RS16340	COG1349	DNA-binding transcription factor activity
HV234_RS16350	COG0023	Translation Initiation Factor
HV234_RS16360	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HV234_RS16365	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HV234_RS16370	COG0671	phosphoesterase, PA-phosphatase related
HV234_RS16380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HV234_RS16405	COG0616	signal peptide processing
HV234_RS16410	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS16415	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HV234_RS16425	COG1472	Belongs to the glycosyl hydrolase 3 family
HV234_RS16430	COG2211	Major facilitator Superfamily
HV234_RS16435	COG1187	pseudouridine synthase activity
HV234_RS16440	COG4907	membrane protein (DUF2207)
HV234_RS16445	COG0009	L-threonylcarbamoyladenylate synthase
HV234_RS16455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HV234_RS16460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV234_RS16460	COG0512	Glutamine amidotransferase of anthranilate synthase
HV234_RS16465	COG0134	indole-3-glycerol-phosphate synthase activity
HV234_RS16465	COG0135	phosphoribosylanthranilate isomerase activity
HV234_RS16485	COG1063	alcohol dehydrogenase
HV234_RS16505	COG3047	cAMP biosynthetic process
HV234_RS16535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV234_RS16540	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS16545	COG1988	membrane-bound metal-dependent
HV234_RS16560	COG0753	catalase activity
HV234_RS16570	COG1486	melibiose metabolic process
HV234_RS16575	COG2169	Transcriptional regulator
HV234_RS16575	COG1917	Cupin 2, conserved barrel domain protein
HV234_RS16580	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV234_RS16585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV234_RS16590	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV234_RS16595	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV234_RS16605	COG0322	excinuclease ABC activity
HV234_RS16610	COG4907	membrane protein (DUF2207)
HV234_RS16615	COG1704	LemA family
HV234_RS16620	COG3678	ATP-independent chaperone mediated protein folding
HV234_RS16640	COG3138	arginine N-succinyltransferase
HV234_RS16650	COG0708	Exodeoxyribonuclease III
HV234_RS16655	COG0398	Pfam SNARE associated Golgi protein
HV234_RS16660	COG0398	Pfam SNARE associated Golgi protein
HV234_RS16665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV234_RS16670	COG4134	Bacterial extracellular solute-binding protein
HV234_RS16675	COG4135	transport system, permease component
HV234_RS16680	COG4136	ATPase activity
HV234_RS16685	COG2897	thiosulfate sulfurtransferase activity
HV234_RS16690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HV234_RS16695	COG0494	nUDIX hydrolase
HV234_RS16705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HV234_RS16710	COG0709	Synthesizes selenophosphate from selenide and ATP
HV234_RS16720	COG0778	Nitroreductase
HV234_RS16725	COG0616	signal peptide processing
HV234_RS16730	COG0252	asparaginase activity
HV234_RS16735	COG1335	isochorismatase
HV234_RS16740	COG2814	Major facilitator Superfamily
HV234_RS16745	COG1349	DNA-binding transcription factor activity
HV234_RS16750	COG0667	Aldo Keto reductase
HV234_RS16755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV234_RS16760	COG0191	fructose-bisphosphate aldolase activity
HV234_RS16765	COG1063	alcohol dehydrogenase
HV234_RS16770	COG2271	Major facilitator Superfamily
HV234_RS16775	COG1063	alcohol dehydrogenase
HV234_RS16790	COG3139	Protein of unknown function (DUF1315)
HV234_RS16810	COG0656	L-ascorbic acid biosynthetic process
HV234_RS16815	COG3713	MltA-interacting MipA family protein
HV234_RS16820	COG2766	serine protein kinase
HV234_RS16830	COG0859	PFAM glycosyl transferase family 9
HV234_RS16860	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV234_RS16895	COG4974	Belongs to the 'phage' integrase family
HV234_RS16900	COG2199	diguanylate cyclase activity
HV234_RS16900	COG2203	Gaf domain
HV234_RS16920	COG3182	Iron-regulated membrane protein
HV234_RS16930	COG1560	Kdo2-lipid A biosynthetic process
HV234_RS16935	COG1595	DNA-templated transcription, initiation
HV234_RS16940	COG3712	iron ion homeostasis
HV234_RS16945	COG4772	TonB-dependent receptor
HV234_RS16950	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HV234_RS16955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV234_RS16960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV234_RS16965	COG1120	ATPase activity
HV234_RS16975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HV234_RS16980	COG3706	GGDEF domain
HV234_RS16985	COG0583	DNA-binding transcription factor activity
HV234_RS17000	COG0538	isocitrate dehydrogenase activity
HV234_RS17025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HV234_RS17040	COG2814	Major facilitator Superfamily
HV234_RS17050	COG0745	RESPONSE REGULATOR receiver
HV234_RS17055	COG2205	protein histidine kinase activity
HV234_RS17060	COG2850	peptidyl-arginine hydroxylation
HV234_RS17080	COG1177	transmembrane transport
HV234_RS17095	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HV234_RS17105	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV234_RS17110	COG1136	(ABC) transporter
HV234_RS17115	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV234_RS17120	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HV234_RS17125	COG1376	ErfK ybiS ycfS ynhG family protein
HV234_RS17125	COG1388	LysM domain
HV234_RS17140	COG1309	transcriptional regulator
HV234_RS17150	COG3134	Outer membrane lipoprotein
HV234_RS17155	COG1252	NADH dehydrogenase
HV234_RS17180	COG5633	Lipoprotein
HV234_RS17185	COG0537	adenosine 5'-monophosphoramidase activity
HV234_RS17190	COG4773	Receptor
HV234_RS17195	COG1263	PTS System
HV234_RS17195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV234_RS17200	COG0084	hydrolase, TatD family'
HV234_RS17205	COG0470	DNA polymerase III
HV234_RS17215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HV234_RS17220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV234_RS17225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV234_RS17240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HV234_RS17260	COG1399	metal-binding, possibly nucleic acid-binding protein
HV234_RS17265	COG0424	maF-like protein
HV234_RS17280	COG1530	ribonuclease E activity
HV234_RS17285	COG0583	DNA-binding transcription factor activity
HV234_RS17290	COG2814	Major facilitator Superfamily
HV234_RS17300	COG0673	inositol 2-dehydrogenase activity
HV234_RS17310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV234_RS17320	COG2999	glutathione oxidoreductase activity
HV234_RS17360	COG1560	Kdo2-lipid A biosynthetic process
HV234_RS17375	COG5645	(Lipo)protein
HV234_RS17415	COG3381	protein complex oligomerization
HV234_RS17615	COG0583	DNA-binding transcription factor activity
HV234_RS17625	COG1335	isochorismatase
HV234_RS17645	COG3850	Histidine kinase
HV234_RS17645	COG5002	protein histidine kinase activity
HV234_RS17665	COG1702	phosphate starvation-inducible protein PhoH
HV234_RS17670	COG2837	iron assimilation
HV234_RS17675	COG2822	iron ion transport
HV234_RS17685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV234_RS17695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV234_RS17710	COG1309	transcriptional regulator
HV234_RS17745	COG2233	PERMEase
HV234_RS17750	COG3729	General stress protein
HV234_RS17780	COG0531	amino acid
HV234_RS17785	COG0174	glutamine synthetase
HV234_RS17790	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HV234_RS17795	COG1396	sequence-specific DNA binding
HV234_RS17795	COG1917	Cupin 2, conserved barrel domain protein
HV234_RS17800	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS17805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HV234_RS17810	COG0583	DNA-binding transcription factor activity
HV234_RS17815	COG0473	3-isopropylmalate dehydrogenase activity
HV234_RS17820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS17820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS17820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV234_RS17825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV234_RS17830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV234_RS17835	COG1882	Formate acetyltransferase
HV234_RS17840	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV234_RS17845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV234_RS17855	COG2207	Transcriptional regulator
HV234_RS17860	COG3706	GGDEF domain
HV234_RS17890	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HV234_RS17955	COG1953	Uracil, thiamine, allantoin
HV234_RS17960	COG0402	S-adenosylhomocysteine deaminase activity
HV234_RS17965	COG2351	hydroxyisourate hydrolase activity
HV234_RS17975	COG2233	PERMEase
HV234_RS17980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV234_RS18035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HV234_RS18045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV234_RS18055	COG1278	Cold shock
HV234_RS18060	COG1278	Cold shock
HV234_RS18080	COG0765	amino acid transport
HV234_RS18095	COG1309	transcriptional regulator
HV234_RS18150	COG0670	Belongs to the BI1 family
HV234_RS18165	COG2207	Transcriptional regulator
HV234_RS18170	COG1881	PFAM PEBP family protein
HV234_RS18190	COG0438	transferase activity, transferring glycosyl groups
HV234_RS18195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV234_RS18200	COG2274	protein secretion by the type I secretion system
HV234_RS18220	COG1832	CoA-binding protein
HV234_RS18230	COG0210	DNA helicase
HV234_RS18235	COG3304	Inner membrane component domain
HV234_RS18240	COG1289	transmembrane transporter activity
HV234_RS18245	COG3070	regulator of competence-specific genes
HV234_RS18265	COG1067	ATP-dependent peptidase activity
HV234_RS18275	COG3130	regulation of translation
HV234_RS18280	COG3009	Protein conserved in bacteria
HV234_RS18285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV234_RS18285	COG3008	intermembrane lipid transfer
HV234_RS18290	COG2995	paraquat-inducible protein a
HV234_RS18295	COG0488	(ABC) transporter
HV234_RS18305	COG0633	Ferredoxin
HV234_RS18305	COG3217	Mosc domain protein beta barrel domain protein
HV234_RS18320	COG0431	NADPH-dependent FMN reductase
HV234_RS18325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV234_RS18335	COG0308	aminopeptidase N
HV234_RS18350	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV234_RS18355	COG1448	Aminotransferase
HV234_RS18360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV234_RS18365	COG3108	Peptidase M15
HV234_RS18370	COG2989	Protein conserved in bacteria
HV234_RS18380	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HV234_RS18390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HV234_RS18395	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV234_RS18400	COG3173	Aminoglycoside phosphotransferase
HV234_RS18415	COG3214	Protein conserved in bacteria
HV234_RS18425	COG1132	(ABC) transporter
HV234_RS18440	COG0539	negative regulation of cytoplasmic translation
HV234_RS18450	COG0501	Belongs to the peptidase M48B family
HV234_RS18465	COG2323	membrane
HV234_RS18470	COG1944	ATP diphosphatase activity
HV234_RS18475	COG2116	formate transmembrane transporter activity
HV234_RS18480	COG1882	Formate acetyltransferase
HV234_RS18485	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV234_RS18490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HV234_RS18505	COG3959	Transketolase, thiamine diphosphate binding domain
HV234_RS18510	COG3958	Transketolase
HV234_RS18515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS18520	COG0477	Major facilitator Superfamily
HV234_RS18525	COG3302	dmso reductase anchor subunit
HV234_RS18530	COG0437	4 iron, 4 sulfur cluster binding
HV234_RS18535	COG0243	molybdopterin cofactor binding
HV234_RS18545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HV234_RS18555	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV234_RS18555	COG1674	ftsk spoiiie
HV234_RS18565	COG0492	ferredoxin-NADP+ reductase activity
HV234_RS18570	COG4988	ABC transporter
HV234_RS18575	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HV234_RS18585	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HV234_RS18590	COG0542	response to heat
HV234_RS18600	COG1278	Cold shock
HV234_RS18610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV234_RS18615	COG3593	DNA synthesis involved in DNA repair
HV234_RS18620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HV234_RS18625	COG2431	L-lysine efflux transmembrane transporter activity
HV234_RS18635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV234_RS18645	COG0028	Belongs to the TPP enzyme family
HV234_RS18650	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HV234_RS18655	COG0702	epimerase
HV234_RS18660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV234_RS18665	COG3023	N-Acetylmuramoyl-L-alanine amidase
HV234_RS18670	COG0393	Putative heavy-metal-binding
HV234_RS18680	COG1126	abc transporter atp-binding protein
HV234_RS18685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV234_RS18690	COG4215	(ABC) transporter
HV234_RS18695	COG4160	amino acid transport
HV234_RS18700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV234_RS18710	COG0745	RESPONSE REGULATOR receiver
HV234_RS18725	COG1177	transmembrane transport
HV234_RS18730	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV234_RS18735	COG3842	ATPase activity
HV234_RS18740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV234_RS18755	COG0778	Nitroreductase
HV234_RS18780	COG3226	Transcriptional regulator
HV234_RS18785	COG0738	Major facilitator superfamily
HV234_RS18790	COG0561	phosphatase activity
HV234_RS18795	COG2814	Major facilitator Superfamily
HV234_RS18800	COG0671	phosphoesterase, PA-phosphatase related
HV234_RS18805	COG1349	DNA-binding transcription factor activity
HV234_RS18810	COG1686	Belongs to the peptidase S11 family
HV234_RS18815	COG0625	glutathione transferase activity
HV234_RS18820	COG2133	pyrroloquinoline quinone binding
HV234_RS18830	COG2223	nitrite transmembrane transporter activity
HV234_RS18855	COG0747	negative chemotaxis
HV234_RS18865	COG1446	asparaginase
HV234_RS18870	COG0303	'Molybdopterin
HV234_RS18875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV234_RS18880	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV234_RS18885	COG1882	Formate acetyltransferase
HV234_RS18890	COG0561	phosphatase activity
HV234_RS18900	COG1609	Transcriptional regulator
HV234_RS18905	COG2271	Major facilitator Superfamily
HV234_RS18915	COG0488	(ABC) transporter
HV234_RS18925	COG1376	ErfK ybiS ycfS ynhG family protein
HV234_RS18930	COG2188	Transcriptional regulator
HV234_RS18935	COG2723	6-phospho-beta-galactosidase activity
HV234_RS18940	COG0667	Aldo Keto reductase
HV234_RS18945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV234_RS18960	COG2194	sulfuric ester hydrolase activity
HV234_RS18965	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HV234_RS18980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV234_RS18985	COG0765	amino acid transport
HV234_RS18990	COG1126	abc transporter atp-binding protein
HV234_RS18995	COG0668	transmembrane transport
HV234_RS19010	COG4774	siderophore transport
HV234_RS19020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV234_RS19030	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV234_RS19040	COG0513	Belongs to the DEAD box helicase family
HV234_RS19045	COG3958	Transketolase
HV234_RS19050	COG3959	Transketolase, thiamine diphosphate binding domain
HV234_RS19055	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS19060	COG2271	Major facilitator Superfamily
HV234_RS19065	COG0583	DNA-binding transcription factor activity
HV234_RS19070	COG1309	transcriptional regulator
HV234_RS19080	COG1131	(ABC) transporter
HV234_RS19085	COG0842	Transport permease protein
HV234_RS19090	COG0842	Transport permease protein
HV234_RS19100	COG3568	Endonuclease Exonuclease Phosphatase
HV234_RS19105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV234_RS19110	COG0392	lysyltransferase activity
HV234_RS19115	COG0670	Belongs to the BI1 family
HV234_RS19120	COG0314	molybdopterin synthase activity
HV234_RS19125	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HV234_RS19135	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV234_RS19180	COG2226	methyltransferase
HV234_RS19195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HV234_RS19200	COG1881	PFAM PEBP family protein
HV234_RS19240	COG4677	pectinesterase activity
HV234_RS19255	COG0789	Transcriptional regulator
HV234_RS19260	COG2200	EAL domain
HV234_RS19280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV234_RS19295	COG0561	phosphatase activity
HV234_RS19305	COG4149	molybdate abc transporter
HV234_RS19310	COG0725	ABC transporter, periplasmic molybdate-binding protein
HV234_RS19320	COG3585	molybdate ion transport
HV234_RS19320	COG2005	Transcriptional regulator
HV234_RS19325	COG1119	ATPase activity
HV234_RS19335	COG1085	galactose-1-phosphate uridylyltransferase
HV234_RS19345	COG2017	converts alpha-aldose to the beta-anomer
HV234_RS19355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV234_RS19370	COG3201	nicotinamide mononucleotide transporter
HV234_RS19375	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HV234_RS19410	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HV234_RS19415	COG2885	chlorophyll binding
HV234_RS19425	COG3064	Membrane
HV234_RS19425	COG3064	Membrane
HV234_RS19430	COG0848	biopolymer transport protein
HV234_RS19435	COG0811	peptide transport
HV234_RS19440	COG0824	Thioesterase
HV234_RS19445	COG3790	cyd operon protein YbgE
HV234_RS19450	COG4890	Cyd operon protein YbgT
HV234_RS19455	COG1294	oxidase, subunit
HV234_RS19460	COG1271	oxidase subunit
HV234_RS19465	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV234_RS19475	COG4865	methylaspartate mutase activity
HV234_RS19480	COG3799	methylaspartate ammonia-lyase activity
HV234_RS19495	COG1301	dicarboxylic acid transport
HV234_RS19505	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV234_RS19505	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV234_RS19515	COG0583	DNA-binding transcription factor activity
HV234_RS19525	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV234_RS19535	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV234_RS19540	COG0567	Dehydrogenase, E1 component
HV234_RS19545	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV234_RS19550	COG1053	succinate dehydrogenase
HV234_RS19555	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HV234_RS19565	COG0372	Belongs to the citrate synthase family
HV234_RS19595	COG1984	allophanate hydrolase subunit 2
HV234_RS19600	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HV234_RS19605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HV234_RS19615	COG0415	Belongs to the DNA photolyase family
HV234_RS19645	COG2205	protein histidine kinase activity
HV234_RS19650	COG0745	RESPONSE REGULATOR receiver
HV234_RS19655	COG0235	Class ii aldolase
HV234_RS19660	COG3623	hexulose-6-phosphate isomerase
HV234_RS19665	COG1070	Carbohydrate kinase
HV234_RS19670	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS19675	COG1129	ABC transporter
HV234_RS19680	COG1879	ABC-type sugar transport system periplasmic component
HV234_RS19695	COG0033	Phosphoglucomutase
HV234_RS19705	COG0596	Alpha beta hydrolase
HV234_RS19720	COG0735	belongs to the Fur family
HV234_RS19725	COG0583	DNA-binding transcription factor activity
HV234_RS19730	COG1053	succinate dehydrogenase
HV234_RS19770	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV234_RS19775	COG1940	carbohydrate kinase activity
HV234_RS19775	COG1846	Transcriptional regulator
HV234_RS19780	COG0647	UMP catabolic process
HV234_RS19785	COG0367	asparagine synthase
HV234_RS19825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV234_RS19835	COG1702	phosphate starvation-inducible protein PhoH
HV234_RS19840	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HV234_RS19845	COG4535	Mg2 and Co2 transporter CorC
HV234_RS19860	COG0765	amino acid transport
HV234_RS19865	COG0765	amino acid transport
HV234_RS19870	COG1126	abc transporter atp-binding protein
HV234_RS19880	COG3210	domain, Protein
HV234_RS19885	COG2888	peptidyl-tyrosine sulfation
HV234_RS19900	COG1466	dna polymerase III delta subunit
HV234_RS19915	COG0799	negative regulation of ribosome biogenesis
HV234_RS19925	COG0768	penicillin binding
HV234_RS19930	COG0772	Belongs to the SEDS family
HV234_RS19935	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV234_RS19940	COG1686	Belongs to the peptidase S11 family
HV234_RS19955	COG0583	DNA-binding transcription factor activity
HV234_RS19965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HV234_RS19970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV234_RS19990	COG3069	C4-dicarboxylate transmembrane transporter activity
HV234_RS19995	COG3719	Belongs to the RNase T2 family
HV234_RS20000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV234_RS20010	COG3634	alkyl hydroperoxide reductase activity
HV234_RS20020	COG0583	DNA-binding transcription factor activity
HV234_RS20025	COG3969	phosphoadenosine phosphosulfate
HV234_RS20030	COG1475	DNA binding
HV234_RS20035	COG0436	Aminotransferase
HV234_RS20040	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
HV234_RS20045	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HV234_RS20060	COG1129	ABC transporter
HV234_RS20065	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS20070	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS20080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV234_RS20100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HV234_RS20110	COG0402	S-adenosylhomocysteine deaminase activity
HV234_RS20120	COG0483	inositol monophosphate 1-phosphatase activity
HV234_RS20125	COG2271	Major facilitator Superfamily
HV234_RS20155	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS20160	COG1129	ABC transporter
HV234_RS20165	COG0371	Dehydrogenase
HV234_RS20180	COG2879	small protein
HV234_RS20185	COG1966	Carbon starvation protein
HV234_RS20195	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS20200	COG1535	isochorismatase
HV234_RS20200	COG3433	isochorismatase activity
HV234_RS20205	COG1021	2,3-dihydroxybenzoate-AMP ligase
HV234_RS20210	COG1169	isochorismate synthase
HV234_RS20215	COG4592	Periplasmic binding protein
HV234_RS20225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV234_RS20230	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV234_RS20235	COG1120	ATPase activity
HV234_RS20240	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HV234_RS20240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HV234_RS20245	COG3251	PFAM MbtH domain protein
HV234_RS20250	COG2382	esterase
HV234_RS20255	COG4771	TonB-dependent receptor
HV234_RS20260	COG2977	Belongs to the P-Pant transferase superfamily
HV234_RS20265	COG3958	Transketolase
HV234_RS20270	COG3959	Transketolase, thiamine diphosphate binding domain
HV234_RS20275	COG2390	Transcriptional regulator
HV234_RS20280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HV234_RS20285	COG1879	ABC-type sugar transport system periplasmic component
HV234_RS20295	COG1129	ABC transporter
HV234_RS20300	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS20310	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS20320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HV234_RS20350	COG4221	oxidoreductase activity
HV234_RS20365	COG0765	amino acid transport
HV234_RS20370	COG0765	amino acid transport
HV234_RS20385	COG1280	lysine exporter protein (LysE YggA)
HV234_RS20395	COG0697	spore germination
HV234_RS20410	COG0444	Belongs to the ABC transporter superfamily
HV234_RS20415	COG4608	Belongs to the ABC transporter superfamily
HV234_RS20420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV234_RS20430	COG4166	transmembrane transport
HV234_RS20440	COG3698	Phosphodiester glycosidase
HV234_RS20470	COG4774	siderophore transport
HV234_RS20490	COG2315	Protein conserved in bacteria
HV234_RS20495	COG0778	Nitroreductase
HV234_RS20505	COG0477	Major facilitator Superfamily
HV234_RS20510	COG0668	transmembrane transport
HV234_RS20515	COG1609	Transcriptional regulator
HV234_RS20520	COG0494	nUDIX hydrolase
HV234_RS20540	COG3188	usher protein
HV234_RS20555	COG2771	luxR family
HV234_RS20560	COG0583	DNA-binding transcription factor activity
HV234_RS20565	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS20580	COG1082	Xylose isomerase domain protein TIM barrel
HV234_RS20585	COG2211	Major facilitator Superfamily
HV234_RS20590	COG1113	amino acid transport
HV234_RS20600	COG0667	Aldo Keto reductase
HV234_RS20605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV234_RS20610	COG1473	amidohydrolase
HV234_RS20650	COG3550	peptidyl-serine autophosphorylation
HV234_RS20660	COG3711	transcriptional antiterminator
HV234_RS20665	COG2723	6-phospho-beta-galactosidase activity
HV234_RS20670	COG1263	PTS System
HV234_RS20670	COG2190	(PTS) system
HV234_RS20670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV234_RS20675	COG0583	DNA-binding transcription factor activity
HV234_RS20715	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS20720	COG1129	ABC transporter
HV234_RS20735	COG0673	inositol 2-dehydrogenase activity
HV234_RS20745	COG2367	Beta-lactamase
HV234_RS20760	COG3104	oligopeptide transport
HV234_RS20765	COG1982	Orn Lys Arg decarboxylase major
HV234_RS20770	COG0531	amino acid
HV234_RS20775	COG3710	Transcriptional regulator
HV234_RS20785	COG0583	DNA-binding transcription factor activity
HV234_RS20795	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HV234_RS20820	COG1285	pathogenesis
HV234_RS20825	COG2211	Major facilitator Superfamily
HV234_RS20855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV234_RS21110	COG0305	Participates in initiation and elongation during chromosome replication
HV234_RS21205	COG0582	viral genome integration into host DNA
HV234_RS21220	COG2501	S4 domain
HV234_RS21230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HV234_RS21245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HV234_RS21250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HV234_RS21255	COG0549	Belongs to the carbamate kinase family
HV234_RS21270	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV234_RS21275	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV234_RS21280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV234_RS21285	COG3257	ureidoglycine aminohydrolase activity
HV234_RS21290	COG1929	Belongs to the glycerate kinase type-1 family
HV234_RS21295	COG2233	PERMEase
HV234_RS21335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV234_RS21345	COG3960	tartronate-semialdehyde synthase activity
HV234_RS21350	COG3622	Belongs to the hyi family
HV234_RS21355	COG2084	Dehydrogenase
HV234_RS21375	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HV234_RS21380	COG4181	ATPase activity
HV234_RS21385	COG2755	lipolytic protein G-D-S-L family
HV234_RS21390	COG0300	oxidoreductase activity
HV234_RS21395	COG3118	belongs to the thioredoxin family
HV234_RS21400	COG0390	transport system, permease component
HV234_RS21405	COG4619	ABC transporter
HV234_RS21410	COG0330	HflC and HflK could
HV234_RS21415	COG1585	Membrane protein implicated in regulation of membrane protease activity
HV234_RS21435	COG0811	peptide transport
HV234_RS21455	COG3735	TraB family
HV234_RS21460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV234_RS21470	COG2223	nitrite transmembrane transporter activity
HV234_RS21475	COG4651	solute:proton antiporter activity
HV234_RS21475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HV234_RS21480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV234_RS21510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HV234_RS21520	COG2832	Protein of unknown function (DUF454)
HV234_RS21525	COG3923	Primosomal replication protein n
HV234_RS21540	COG1196	nuclear chromosome segregation
HV234_RS21540	COG3264	Mechanosensitive ion channel
HV234_RS21545	COG1309	transcriptional regulator
HV234_RS21550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV234_RS21555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV234_RS21575	COG0110	maltose O-acetyltransferase activity
HV234_RS21595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HV234_RS21615	COG1263	PTS System
HV234_RS21615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV234_RS21620	COG1874	Beta-galactosidase
HV234_RS21625	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HV234_RS21630	COG3833	ABC-type maltose transport systems, permease component
HV234_RS21635	COG1175	transmembrane transport
HV234_RS21640	COG2182	Extracellular solute-binding protein
HV234_RS21650	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV234_RS21665	COG5507	3-demethylubiquinone-9 3-methyltransferase
HV234_RS21670	COG2364	Membrane
HV234_RS21700	COG3695	enzyme binding
HV234_RS21705	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HV234_RS21710	COG1946	Acyl-CoA thioesterase
HV234_RS21715	COG0583	DNA-binding transcription factor activity
HV234_RS21720	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV234_RS21725	COG1811	Na channel or pump
HV234_RS21730	COG0004	ammonium transporteR
HV234_RS21735	COG0347	Belongs to the P(II) protein family
HV234_RS21740	COG1132	(ABC) transporter
HV234_RS21745	COG1132	(ABC) transporter
HV234_RS21750	COG1522	sequence-specific DNA binding
HV234_RS21765	COG4533	DNA binding
HV234_RS21775	COG0824	Thioesterase
HV234_RS21780	COG1555	photosystem II stabilization
HV234_RS21785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV234_RS21790	COG0776	regulation of translation
HV234_RS21795	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HV234_RS21815	COG0271	Belongs to the BolA IbaG family
HV234_RS21820	COG3056	Lipoprotein
HV234_RS21825	COG2223	nitrite transmembrane transporter activity
HV234_RS21830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HV234_RS21835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HV234_RS21840	COG1845	cytochrome c oxidase, subunit III
HV234_RS21845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HV234_RS21860	COG1414	Transcriptional regulator
HV234_RS21895	COG2211	Major facilitator Superfamily
HV234_RS21900	COG0673	inositol 2-dehydrogenase activity
HV234_RS21905	COG2814	Major facilitator Superfamily
HV234_RS21915	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HV234_RS21935	COG0142	geranyltranstransferase activity
HV234_RS21945	COG0667	Aldo Keto reductase
HV234_RS21950	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HV234_RS21955	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HV234_RS21970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV234_RS21970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV234_RS21980	COG4238	major outer membrane lipoprotein
HV234_RS22005	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV234_RS22010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV234_RS22015	COG1862	Preprotein translocase
HV234_RS22030	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HV234_RS22035	COG0450	alkyl hydroperoxide reductase
HV234_RS22050	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HV234_RS22060	COG1335	isochorismatase
HV234_RS22065	COG0583	DNA-binding transcription factor activity
HV234_RS22070	COG0366	Alpha amylase catalytic
HV234_RS22095	COG0420	3'-5' exonuclease activity
HV234_RS22100	COG0419	ATPase involved in DNA repair
HV234_RS22110	COG1940	carbohydrate kinase activity
HV234_RS22125	COG4126	flavin adenine dinucleotide binding
HV234_RS22135	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HV234_RS22140	COG3416	Protein conserved in bacteria
HV234_RS22150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HV234_RS22160	COG1785	Belongs to the alkaline phosphatase family
HV234_RS22170	COG1609	Transcriptional regulator
HV234_RS22180	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS22215	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HV234_RS22225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HV234_RS22230	COG0113	porphobilinogen synthase activity
HV234_RS22245	COG2175	clavaminate synthase activity
HV234_RS22250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV234_RS22255	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HV234_RS22260	COG4521	taurine ABC transporter
HV234_RS22275	COG2271	Major facilitator Superfamily
HV234_RS22280	COG1840	ABC-type Fe3 transport system, periplasmic component
HV234_RS22290	COG3842	ATPase activity
HV234_RS22295	COG2040	homocysteine
HV234_RS22300	COG0833	amino acid
HV234_RS22305	COG5434	Belongs to the glycosyl hydrolase 28 family
HV234_RS22310	COG0531	amino acid
HV234_RS22315	COG4303	Ethanolamine ammonia lyase large subunit
HV234_RS22320	COG4302	ethanolamine ammonia-lyase activity
HV234_RS22360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV234_RS22365	COG1126	abc transporter atp-binding protein
HV234_RS22370	COG0765	amino acid transport
HV234_RS22375	COG0765	amino acid transport
HV234_RS22390	COG3188	usher protein
HV234_RS22420	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HV234_RS22430	COG3639	organic phosphonate transmembrane transporter activity
HV234_RS22450	COG3118	belongs to the thioredoxin family
HV234_RS22460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV234_RS22470	COG0583	DNA-binding transcription factor activity
HV234_RS22475	COG0791	NLP P60 protein
HV234_RS22480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV234_RS22485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HV234_RS22490	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HV234_RS22525	COG3093	addiction module antidote protein HigA
HV234_RS22550	COG3846	protein secretion by the type IV secretion system
HV234_RS22585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV234_RS22595	COG1733	regulation of RNA biosynthetic process
HV234_RS22600	COG2085	NADP oxidoreductase coenzyme F420-dependent
HV234_RS22605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV234_RS22620	COG1309	transcriptional regulator
HV234_RS22630	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV234_RS22640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV234_RS22650	COG0477	Major facilitator Superfamily
HV234_RS22660	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HV234_RS22665	COG3153	acetyltransferase
HV234_RS22680	COG0246	Mannitol dehydrogenase
HV234_RS22685	COG2186	Transcriptional regulator
HV234_RS22705	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS22710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HV234_RS22720	COG1596	polysaccharide export
HV234_RS22740	COG0463	Glycosyl transferase, family 2
HV234_RS22745	COG0438	transferase activity, transferring glycosyl groups
HV234_RS22750	COG0297	glycogen (starch) synthase activity
HV234_RS22750	COG0438	transferase activity, transferring glycosyl groups
HV234_RS22765	COG1045	serine acetyltransferase
HV234_RS22785	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV234_RS22790	COG0454	-acetyltransferase
HV234_RS22805	COG2991	Protein conserved in bacteria
HV234_RS22820	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV234_RS22825	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV234_RS22840	COG3034	peptidoglycan biosynthetic process
HV234_RS22845	COG0121	glutamine amidotransferase
HV234_RS22855	COG1960	acyl-CoA dehydrogenase activity
HV234_RS22860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV234_RS22880	COG2226	methyltransferase
HV234_RS22890	COG1388	LysM domain
HV234_RS22890	COG0741	lytic transglycosylase activity
HV234_RS22895	COG2226	methyltransferase
HV234_RS22905	COG2814	Major facilitator Superfamily
HV234_RS22910	COG0583	DNA-binding transcription factor activity
HV234_RS22915	COG0656	L-ascorbic acid biosynthetic process
HV234_RS22950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HV234_RS22960	COG2011	ABC-type metal ion transport system permease component
HV234_RS22965	COG1464	Belongs to the NlpA lipoprotein family
HV234_RS22975	COG1720	tRNA m6t6A37 methyltransferase activity
HV234_RS22985	COG3015	lipoprotein NlpE involved in copper resistance
HV234_RS22990	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HV234_RS22995	COG4681	YaeQ
HV234_RS23005	COG4568	rho-dependent transcription termination
HV234_RS23015	COG0346	lactoylglutathione lyase activity
HV234_RS23050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HV234_RS23055	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HV234_RS23060	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HV234_RS23070	COG0750	zinc metalloprotease
HV234_RS23075	COG0575	Belongs to the CDS family
HV234_RS23085	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HV234_RS23100	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HV234_RS23110	COG0024	Methionine aminopeptidase
HV234_RS23115	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HV234_RS23130	COG3835	regulator
HV234_RS23135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV234_RS23155	COG2860	membrane
HV234_RS23175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV234_RS23180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV234_RS23185	COG1120	ATPase activity
HV234_RS23190	COG4774	siderophore transport
HV234_RS23195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HV234_RS23290	COG1643	Atp-dependent helicase
HV234_RS23295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HV234_RS23315	COG0617	tRNA 3'-terminal CCA addition
HV234_RS23320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HV234_RS23335	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HV234_RS23340	COG0726	polysaccharide deacetylase
HV234_RS23345	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS23350	COG0842	Transport permease protein
HV234_RS23355	COG1131	(ABC) transporter
HV234_RS23360	COG0288	reversible hydration of carbon dioxide
HV234_RS23370	COG4993	Dehydrogenase
HV234_RS23375	COG2132	Multicopper oxidase
HV234_RS23395	COG0545	Peptidyl-prolyl cis-trans isomerase
HV234_RS23420	COG3064	Membrane
HV234_RS23435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV234_RS23440	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV234_RS23445	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HV234_RS23450	COG2186	Transcriptional regulator
HV234_RS23455	COG1113	amino acid transport
HV234_RS23460	COG2211	Major facilitator Superfamily
HV234_RS23465	COG3940	Belongs to the glycosyl hydrolase 43 family
HV234_RS23470	COG3725	Membrane protein required for beta-lactamase induction
HV234_RS23485	COG4969	Belongs to the N-Me-Phe pilin family
HV234_RS23490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV234_RS23495	COG1459	type II secretion system
HV234_RS23520	COG0494	nUDIX hydrolase
HV234_RS23540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HV234_RS23545	COG0849	cell division
HV234_RS23570	COG0772	Belongs to the SEDS family
HV234_RS23585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HV234_RS23595	COG0768	penicillin binding
HV234_RS23615	COG1609	Transcriptional regulator
HV234_RS23625	COG0028	Belongs to the TPP enzyme family
HV234_RS23645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HV234_RS23670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV234_RS23675	COG0738	Major facilitator superfamily
HV234_RS23685	COG0583	DNA-binding transcription factor activity
HV234_RS23690	COG2271	Major facilitator Superfamily
HV234_RS23695	COG2814	Major facilitator Superfamily
HV234_RS23715	COG1178	ABC-type Fe3 transport system permease component
HV234_RS23725	COG0586	Pfam SNARE associated Golgi protein
HV234_RS23745	COG0235	Class ii aldolase
HV234_RS23750	COG0417	DNA replication proofreading
HV234_RS23760	COG0564	pseudouridine synthase activity
HV234_RS23770	COG3493	citrate carrier protein
HV234_RS23785	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HV234_RS23845	COG1940	carbohydrate kinase activity
HV234_RS23920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HV234_RS23935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HV234_RS23940	COG0471	metal ion transport
HV234_RS23945	COG0471	metal ion transport
HV234_RS23950	COG2828	Protein conserved in bacteria
HV234_RS23955	COG0583	DNA-binding transcription factor activity
HV234_RS23970	COG1047	Peptidyl-prolyl cis-trans
HV234_RS23985	COG0196	riboflavin kinase activity
HV234_RS23995	COG0583	DNA-binding transcription factor activity
HV234_RS24030	COG4735	regulation of single-species biofilm formation
HV234_RS24035	COG1584	GPR1 FUN34 yaaH family protein
HV234_RS24045	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV234_RS24050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HV234_RS24055	COG1115	amino acid carrier protein
HV234_RS24065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HV234_RS24075	COG0460	homoserine dehydrogenase
HV234_RS24075	COG0527	aspartate kinase activity
HV234_RS24085	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HV234_RS24095	COG0745	RESPONSE REGULATOR receiver
HV234_RS24100	COG4452	Inner membrane protein CreD
HV234_RS24105	COG2205	protein histidine kinase activity
HV234_RS24110	COG0745	RESPONSE REGULATOR receiver
HV234_RS24115	COG3045	CreA protein
HV234_RS24120	COG2207	Transcriptional regulator
HV234_RS24120	COG3708	Transcriptional regulator
HV234_RS24140	COG0741	lytic transglycosylase activity
HV234_RS24145	COG0488	(ABC) transporter
HV234_RS24155	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HV234_RS24160	COG0560	Phosphoserine phosphatase
HV234_RS24165	COG3726	membrane protein affecting hemolysin expression
HV234_RS24175	COG0813	purine-nucleoside phosphorylase activity
HV234_RS24195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV234_RS24200	COG0084	hydrolase, TatD family'
HV234_RS24205	COG4667	esterase of the alpha-beta hydrolase superfamily
HV234_RS24210	COG5487	UPF0391 membrane protein
HV234_RS24215	COG2823	Periplasmic or secreted lipoprotein
HV234_RS24225	COG1011	Hydrolase
HV234_RS24230	COG0456	acetyltransferase
HV234_RS24235	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HV234_RS24265	COG3706	GGDEF domain
HV234_RS24270	COG4114	ferric iron reductase
HV234_RS24275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV234_RS24280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV234_RS24285	COG2197	response regulator
HV234_RS24290	COG2197	response regulator
HV234_RS24295	COG2207	Transcriptional regulator
HV234_RS24305	COG2966	Psort location CytoplasmicMembrane, score
HV234_RS24320	COG1484	DNA-dependent DNA replication
HV234_RS24335	COG5464	transposase or invertase
HV234_RS24345	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HV234_RS24350	COG3716	PTS system mannose fructose sorbose family IID component
HV234_RS24355	COG3715	PTS system
HV234_RS24370	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HV234_RS24370	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV234_RS24380	COG1063	alcohol dehydrogenase
HV234_RS24385	COG1802	Transcriptional regulator
HV234_RS24390	COG2271	Major facilitator Superfamily
HV234_RS24395	COG0456	acetyltransferase
HV234_RS24405	COG1737	Transcriptional regulator
HV234_RS24410	COG0800	Aldolase
HV234_RS24415	COG3734	2-keto-3-deoxy-galactonokinase
HV234_RS24420	COG4145	pantothenate transmembrane transporter activity
HV234_RS24430	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HV234_RS24440	COG1846	Transcriptional regulator
HV234_RS24445	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV234_RS24455	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS24460	COG3384	dioxygenase
HV234_RS24470	COG3971	2-oxopent-4-enoate hydratase activity
HV234_RS24490	COG2368	4-hydroxyphenylacetate
HV234_RS24495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV234_RS24500	COG1966	Carbon starvation protein
HV234_RS24505	COG2879	small protein
HV234_RS24510	COG0523	cobalamin synthesis protein
HV234_RS24525	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS24550	COG3039	Transposase
HV234_RS24555	COG2733	membrane
HV234_RS24560	COG2814	Major facilitator Superfamily
HV234_RS24565	COG1475	DNA binding
HV234_RS24570	COG3969	phosphoadenosine phosphosulfate
HV234_RS24580	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HV234_RS24585	COG1924	4 iron, 4 sulfur cluster binding
HV234_RS24595	COG1473	amidohydrolase
HV234_RS24600	COG0700	Nucleoside recognition
HV234_RS24605	COG3366	ferrous iron transmembrane transporter activity
HV234_RS24610	COG0583	DNA-binding transcription factor activity
HV234_RS24620	COG1566	PFAM secretion protein HlyD family protein
HV234_RS24630	COG5457	Domain of unknown function (DUF1127)
HV234_RS24635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV234_RS24640	COG1715	Restriction endonuclease
HV234_RS24645	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HV234_RS24650	COG0732	type I restriction modification DNA specificity domain
HV234_RS24685	COG2850	peptidyl-arginine hydroxylation
HV234_RS24690	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HV234_RS24695	COG0588	phosphoglycerate mutase activity
HV234_RS24705	COG0477	Major facilitator Superfamily
HV234_RS24715	COG0477	Major facilitator Superfamily
HV234_RS24720	COG4948	Mandelate Racemase Muconate Lactonizing
HV234_RS24725	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS24730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV234_RS24815	COG2003	Belongs to the UPF0758 family
HV234_RS24850	COG3039	Transposase
HV234_RS24875	COG1061	Type III restriction enzyme res subunit
HV234_RS24910	COG0582	viral genome integration into host DNA
HV234_RS24920	COG1064	alcohol dehydrogenase
HV234_RS24925	COG1175	transmembrane transport
HV234_RS24930	COG0395	ABC-type sugar transport system, permease component
HV234_RS24935	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HV234_RS24940	COG3842	ATPase activity
HV234_RS24950	COG2814	Major facilitator Superfamily
HV234_RS24960	COG1082	Xylose isomerase domain protein TIM barrel
HV234_RS24970	COG3962	Belongs to the TPP enzyme family
HV234_RS24975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV234_RS24980	COG0837	glucose binding
HV234_RS24980	COG1737	Transcriptional regulator
HV234_RS24985	COG3718	enzyme involved in inositol metabolism
HV234_RS25000	COG0433	COG0433 Predicted ATPase
HV234_RS25005	COG0795	lipopolysaccharide-transporting ATPase activity
HV234_RS25010	COG0795	lipopolysaccharide-transporting ATPase activity
HV234_RS25020	COG2927	DNA polymerase III (CHI subunit)
HV234_RS25025	COG0525	valine-tRNA ligase activity
HV234_RS25050	COG2731	YhcH YjgK YiaL family protein
HV234_RS25075	COG0251	oxidation-reduction process
HV234_RS25090	COG1263	PTS System
HV234_RS25090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV234_RS25095	COG0366	Alpha amylase catalytic
HV234_RS25100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV234_RS25105	COG1486	melibiose metabolic process
HV234_RS25125	COG0602	queuosine metabolic process
HV234_RS25130	COG3501	Rhs element vgr protein
HV234_RS25145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV234_RS25145	COG3711	transcriptional antiterminator
HV234_RS25150	COG2706	6-phosphogluconolactonase activity
HV234_RS25165	COG3964	amidohydrolase
HV234_RS25200	COG0312	modulator of DNA gyrase
HV234_RS25210	COG1012	belongs to the aldehyde dehydrogenase family
HV234_RS25230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HV234_RS25240	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS25245	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS25250	COG1129	ABC transporter
HV234_RS25255	COG1879	ABC-type sugar transport system periplasmic component
HV234_RS25265	COG2105	PFAM AIG2 family protein
HV234_RS25270	COG2911	Protein conserved in bacteria
HV234_RS25275	COG0729	surface antigen
HV234_RS25285	COG1253	flavin adenine dinucleotide binding
HV234_RS25310	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HV234_RS25325	COG1733	regulation of RNA biosynthetic process
HV234_RS25330	COG0702	epimerase
HV234_RS25340	COG0697	spore germination
HV234_RS25350	COG1113	amino acid transport
HV234_RS25355	COG0545	Peptidyl-prolyl cis-trans isomerase
HV234_RS25360	COG3061	Opacity-associated protein A
HV234_RS25370	COG0359	binds to the 23S rRNA
HV234_RS25375	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HV234_RS25380	COG2965	DNA replication, synthesis of RNA primer
HV234_RS25440	COG1073	alpha beta
HV234_RS25445	COG3650	response to hydrogen peroxide
HV234_RS25455	COG1960	acyl-CoA dehydrogenase activity
HV234_RS25465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV234_RS25470	COG0557	exoribonuclease II activity
HV234_RS25485	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HV234_RS25495	COG0330	HflC and HflK could
HV234_RS25500	COG0330	HflC and HflK could
HV234_RS25505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HV234_RS25525	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV234_RS25530	COG0802	atpase or kinase
HV234_RS25535	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HV234_RS25535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HV234_RS25540	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HV234_RS25560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV234_RS25565	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HV234_RS25580	COG3264	Mechanosensitive ion channel
HV234_RS25580	COG1511	domain protein
HV234_RS25590	COG1053	succinate dehydrogenase
HV234_RS25595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV234_RS25610	COG3040	lipid binding
HV234_RS25615	COG2076	Multidrug Resistance protein
HV234_RS25695	COG0459	protein refolding
HV234_RS25705	COG0531	amino acid
HV234_RS25710	COG3030	protein affecting phage T7 exclusion by the F plasmid
HV234_RS25715	COG1027	Aspartate ammonia-lyase
HV234_RS25720	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV234_RS25735	COG1309	transcriptional regulator
HV234_RS25750	COG0582	viral genome integration into host DNA
HV234_RS25785	COG0463	Glycosyl transferase, family 2
HV234_RS25800	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV234_RS25815	COG0861	Integral membrane protein TerC family
HV234_RS25835	COG2824	Alkylphosphonate utilization operon protein PhnA
HV234_RS25840	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HV234_RS25845	COG2188	Transcriptional regulator
HV234_RS25850	COG3624	Phosphonate C-P lyase system protein PhnG
HV234_RS25855	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HV234_RS25860	COG3626	phosphonate metabolism
HV234_RS25865	COG3627	carbon phosphorus lyase activity
HV234_RS25870	COG4107	phosphonate C-P lyase system protein PhnK
HV234_RS25875	COG4778	phosphonate C-P lyase system protein PhnL
HV234_RS25880	COG3454	Phosphonate metabolism
HV234_RS25885	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HV234_RS25890	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HV234_RS25900	COG0698	ribose 5-phosphate isomerase
HV234_RS25905	COG1737	Transcriptional regulator
HV234_RS25910	COG1879	ABC-type sugar transport system periplasmic component
HV234_RS25915	COG1129	ABC transporter
HV234_RS25920	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS25925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV234_RS25930	COG1940	carbohydrate kinase activity
HV234_RS25935	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HV234_RS25945	COG1566	PFAM secretion protein HlyD family protein
HV234_RS25950	COG1289	transmembrane transporter activity
HV234_RS25960	COG3383	formate dehydrogenase (NAD+) activity
HV234_RS25965	COG3383	formate dehydrogenase (NAD+) activity
HV234_RS25970	COG3383	formate dehydrogenase (NAD+) activity
HV234_RS25975	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HV234_RS25980	COG1301	dicarboxylic acid transport
HV234_RS25985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HV234_RS25990	COG3162	membrane
HV234_RS25995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV234_RS26030	COG1380	Effector of murein hydrolase LrgA
HV234_RS26035	COG0583	DNA-binding transcription factor activity
HV234_RS26050	COG0679	Auxin Efflux Carrier
HV234_RS26060	COG0025	NhaP-type Na H and K H
HV234_RS26065	COG2252	PERMEase
HV234_RS26115	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV234_RS26125	COG4771	TonB-dependent receptor
HV234_RS26135	COG0629	single-stranded DNA binding
HV234_RS26140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HV234_RS26155	COG2315	Protein conserved in bacteria
HV234_RS26160	COG0432	Pfam Uncharacterised protein family UPF0047
HV234_RS26170	COG1448	Aminotransferase
HV234_RS26175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HV234_RS26180	COG0305	Participates in initiation and elongation during chromosome replication
HV234_RS26195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV234_RS26205	COG0735	belongs to the Fur family
HV234_RS26210	COG3237	CsbD-like
HV234_RS26215	COG0534	Mate efflux family protein
HV234_RS26225	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HV234_RS26250	COG4580	involved in the transport of maltose and maltodextrins
HV234_RS26285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HV234_RS26295	COG0527	aspartate kinase activity
HV234_RS26300	COG3541	Predicted nucleotidyltransferase
HV234_RS26315	COG4650	regulator
HV234_RS26330	COG1187	pseudouridine synthase activity
HV234_RS26370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV234_RS26425	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HV234_RS26465	COG0151	Belongs to the GarS family
HV234_RS26475	COG4191	Histidine kinase
HV234_RS26515	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HV234_RS26530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV234_RS26535	COG2104	thiamine diphosphate biosynthetic process
HV234_RS26550	COG3706	GGDEF domain
HV234_RS26560	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV234_RS26565	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV234_RS26600	COG0250	Participates in transcription elongation, termination and antitermination
HV234_RS26605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HV234_RS26645	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HV234_RS26675	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HV234_RS26685	COG1739	Uncharacterized protein family UPF0029
HV234_RS26730	COG0805	protein transport
HV234_RS26735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HV234_RS26750	COG3165	ubiquinone biosynthetic process from chorismate
HV234_RS26770	COG0412	Dienelactone hydrolase
HV234_RS26785	COG0583	DNA-binding transcription factor activity
HV234_RS26790	COG0697	spore germination
HV234_RS26795	COG0561	phosphatase activity
HV234_RS26800	COG2267	carboxylic ester hydrolase activity
HV234_RS26805	COG1280	lysine exporter protein (LysE YggA)
HV234_RS26815	COG1280	lysine exporter protein (LysE YggA)
HV234_RS26830	COG2050	protein possibly involved in aromatic compounds catabolism
HV234_RS26840	COG0598	Magnesium transport protein CorA
HV234_RS26845	COG0210	DNA helicase
HV234_RS26850	COG1011	Hydrolase
HV234_RS26870	COG5567	small periplasmic lipoprotein
HV234_RS26880	COG3072	Adenylate cyclase
HV234_RS26890	COG1587	Uroporphyrinogen-III synthase
HV234_RS26895	COG2959	enzyme of heme biosynthesis
HV234_RS26900	COG3071	HemY protein
HV234_RS26945	COG2244	polysaccharide biosynthetic process
HV234_RS26950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HV234_RS26955	COG0456	acetyltransferase
HV234_RS26960	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HV234_RS26965	COG1088	dTDP-glucose 4,6-dehydratase activity
HV234_RS26970	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HV234_RS26975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HV234_RS26985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HV234_RS26990	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HV234_RS26995	COG3118	belongs to the thioredoxin family
HV234_RS27010	COG0583	DNA-binding transcription factor activity
HV234_RS27020	COG1811	Na channel or pump
HV234_RS27030	COG1397	ADP-ribosylglycohydrolase
HV234_RS27040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV234_RS27055	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HV234_RS27065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV234_RS27070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV234_RS27080	COG0583	DNA-binding transcription factor activity
HV234_RS27085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV234_RS27095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV234_RS27100	COG3978	acetolactate synthase activity
HV234_RS27120	COG3085	chromosome segregation
HV234_RS27195	COG0583	DNA-binding transcription factor activity
HV234_RS27210	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HV234_RS27225	COG3443	Belongs to the bacterial solute-binding protein 9 family
HV234_RS27230	COG2207	Transcriptional regulator
HV234_RS27240	COG0371	Dehydrogenase
HV234_RS27245	COG1349	DNA-binding transcription factor activity
HV234_RS27255	COG0583	DNA-binding transcription factor activity
HV234_RS27260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV234_RS27265	COG0460	homoserine dehydrogenase
HV234_RS27265	COG0527	aspartate kinase activity
HV234_RS27270	COG0626	cystathionine gamma-synthase activity
HV234_RS27285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HV234_RS27290	COG1609	Transcriptional regulator
HV234_RS27295	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV234_RS27310	COG1575	Belongs to the MenA family. Type 1 subfamily
HV234_RS27330	COG3678	ATP-independent chaperone mediated protein folding
HV234_RS27335	COG0745	RESPONSE REGULATOR receiver
HV234_RS27340	COG2205	protein histidine kinase activity
HV234_RS27345	COG2258	MOSC domain
HV234_RS27390	COG1129	ABC transporter
HV234_RS27405	COG1454	alcohol dehydrogenase
HV234_RS27420	COG2211	Major facilitator Superfamily
HV234_RS27445	COG0110	maltose O-acetyltransferase activity
HV234_RS27450	COG2211	Major facilitator Superfamily
HV234_RS27465	COG2271	Major facilitator Superfamily
HV234_RS27470	COG2731	YhcH YjgK YiaL family protein
HV234_RS27475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV234_RS27480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV234_RS27490	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV234_RS27530	COG0205	6-phosphofructokinase activity
HV234_RS27555	COG3715	PTS system
HV234_RS27560	COG3716	PTS system mannose fructose sorbose family IID component
HV234_RS27590	COG0437	4 iron, 4 sulfur cluster binding
HV234_RS27595	COG2864	formate dehydrogenase
HV234_RS27610	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV234_RS27620	COG0456	acetyltransferase
HV234_RS27625	COG1490	D-aminoacyl-tRNA deacylase activity
HV234_RS27635	COG1011	Hydrolase
HV234_RS27650	COG3852	Histidine kinase
HV234_RS27665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV234_RS27685	COG0204	Acyl-transferase
HV234_RS27695	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HV234_RS27700	COG3084	Protein conserved in bacteria
HV234_RS27710	COG1763	Mo-molybdopterin cofactor biosynthetic process
HV234_RS27730	COG2186	Transcriptional regulator
HV234_RS27735	COG0477	Major facilitator Superfamily
HV234_RS27740	COG1609	Transcriptional regulator
HV234_RS27745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV234_RS27755	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV234_RS27760	COG1129	ABC transporter
HV234_RS27790	COG1522	sequence-specific DNA binding
HV234_RS27795	COG0716	FMN binding
HV234_RS27810	COG3312	ion transport
HV234_RS27870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HV234_RS27875	COG0573	inorganic phosphate transmembrane transporter activity
HV234_RS27880	COG0581	inorganic phosphate transmembrane transporter activity
HV234_RS27885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HV234_RS27890	COG0704	Plays a role in the regulation of phosphate uptake
HV234_RS27905	COG2382	esterase
HV234_RS27910	COG0363	glucosamine-6-phosphate deaminase activity
HV234_RS27915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV234_RS27920	COG2252	PERMEase
HV234_RS27925	COG0431	NADPH-dependent FMN reductase
HV234_RS27930	COG2091	lysine biosynthetic process via aminoadipic acid
HV234_RS27945	COG2731	YhcH YjgK YiaL family protein
HV234_RS27965	COG1737	Transcriptional regulator
HV234_RS27970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV234_RS27975	COG0456	acetyltransferase
HV234_RS27990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HV234_RS28000	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HV234_RS28070	COG3436	PFAM IS66 Orf2 family protein
HV234_RS28075	COG4372	Transposase
HV234_RS28080	COG1192	Involved in chromosome partitioning
HV234_RS28165	COG0210	DNA helicase
HV234_RS28350	COG3550	peptidyl-serine autophosphorylation
HV234_RS28380	COG0625	glutathione transferase activity
HV234_RS28385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV234_RS28400	COG0583	DNA-binding transcription factor activity
HV234_RS28410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV234_RS28425	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HV234_RS28445	COG1846	Transcriptional regulator
HV234_RS28450	COG0583	DNA-binding transcription factor activity
HV234_RS28460	COG2948	multi-organism process
HV234_RS28515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV234_RS28610	COG5433	transposase activity
HV234_RS28655	COG3039	Transposase
HV234_RS28660	COG1528	Iron-storage protein
HV234_RS28670	COG0789	Transcriptional regulator
HV234_RS28710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV234_RS28725	COG1342	Belongs to the UPF0251 family
HV234_RS28740	COG0783	Belongs to the Dps family
HV234_RS28745	COG0640	Transcriptional regulator
HV234_RS28750	COG0446	pyridine nucleotide-disulphide oxidoreductase
HV234_RS28790	COG0270	DNA (cytosine-5-)-methyltransferase activity
HV234_RS28815	COG0659	secondary active sulfate transmembrane transporter activity
HV234_RS28820	COG0589	response to stress
HV234_RS28825	COG1393	Belongs to the ArsC family
HV234_RS28830	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV234_RS28835	COG0640	Transcriptional regulator
HV234_RS28840	COG0431	NADPH-dependent FMN reductase
HV234_RS28845	COG2801	Transposase and inactivated derivatives
HV234_RS28855	COG2801	Transposase and inactivated derivatives
HV234_RS28870	COG3039	Transposase
HV234_RS28885	COG3039	Transposase
HV234_RS28935	COG1358	cellular component organization or biogenesis
HV234_RS28965	COG4245	von Willebrand factor, type A
HV234_RS29010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HV234_RS29190	COG2026	Addiction module toxin, RelE StbE family
HV234_RS29195	COG3077	Addiction module antitoxin, RelB DinJ family
HV234_RS29200	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HV234_RS29210	COG3547	Transposase (IS116 IS110 IS902 family)
HV234_RS29215	COG2801	Transposase and inactivated derivatives
HV234_RS29350	COG5654	RES domain protein
HV234_RS29355	COG5642	Protein of unknown function (DUF2384)
HV234_RS29505	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV234_RS29555	COG0604	alcohol dehydrogenase
HV234_RS29555	COG1028	Short-chain dehydrogenase reductase Sdr
HV234_RS29555	COG3321	synthase
HV234_RS29635	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HV234_RS29660	COG3318	Belongs to the UPF0149 family
HV234_RS29660	COG3012	SEC-C Motif Domain Protein
HV234_RS29665	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HV234_RS29740	COG0583	DNA-binding transcription factor activity
HV234_RS29745	COG3547	Transposase (IS116 IS110 IS902 family)
HV234_RS29765	COG2223	nitrite transmembrane transporter activity
HV234_RS29775	COG1609	Transcriptional regulator
HV234_RS29795	COG3436	PFAM IS66 Orf2 family protein
HV234_RS29805	COG3429	Glucose-6-phosphate dehydrogenase subunit
HV234_RS29805	COG3409	Peptidoglycan-binding domain 1 protein
HV234_RS29850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV234_RS29910	COG0542	response to heat
HV234_RS29915	COG0071	Belongs to the small heat shock protein (HSP20) family
HV234_RS29955	COG2801	Transposase and inactivated derivatives
HV234_RS29965	COG2801	Transposase and inactivated derivatives
HV234_RS30030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV234_RS30060	COG0431	NADPH-dependent FMN reductase
HV234_RS30075	COG3436	PFAM IS66 Orf2 family protein
HV234_RS30080	COG4372	Transposase
HV234_RS30090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HV234_RS30110	COG2205	protein histidine kinase activity
HV234_RS30115	COG0745	RESPONSE REGULATOR receiver
HV234_RS30120	COG1276	copper resistance
HV234_RS30125	COG2372	response to copper ion
HV234_RS30130	COG3667	copper resistance
HV234_RS30135	COG2132	Multicopper oxidase
HV234_RS30145	COG0739	heme binding
HV234_RS30175	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV234_RS30245	COG1716	ATPase activity
HV234_RS30245	COG5001	Diguanylate cyclase
HV234_RS30250	COG2199	diguanylate cyclase activity
HV234_RS30250	COG2203	Gaf domain
HV234_RS30320	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HV234_RS30395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV234_RS30405	COG0589	response to stress
HV234_RS30460	COG1127	ABC transporter
HV234_RS30465	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV234_RS30490	COG3039	Transposase
HV234_RS30520	COG0058	SHG alpha-glucan phosphorylase activity
HV234_RS30525	COG0033	Phosphoglucomutase
HV234_RS30535	COG3436	PFAM IS66 Orf2 family protein
HV234_RS30540	COG4372	Transposase
HV234_RS30600	COG3692	DNA binding
HV234_RS30610	COG1192	Involved in chromosome partitioning
HV234_RS30675	COG0629	single-stranded DNA binding
HV234_RS30685	COG1475	DNA binding
HV234_RS30980	COG4644	lycopene metabolic process
HV234_RS31030	COG2161	toxin-antitoxin pair type II binding
HV234_RS31035	COG4115	mRNA cleavage