locus-tag	class	description
HV240_RS00010	COG0592	DNA-directed DNA polymerase activity
HV240_RS00025	COG0583	DNA-binding transcription factor activity
HV240_RS00035	COG0561	phosphatase activity
HV240_RS00040	COG2186	Transcriptional regulator
HV240_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
HV240_RS00050	COG0800	Aldolase
HV240_RS00065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HV240_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
HV240_RS00075	COG5645	(Lipo)protein
HV240_RS00100	COG2188	Transcriptional regulator
HV240_RS00115	COG2149	membrane
HV240_RS00125	COG0641	radical SAM
HV240_RS00135	COG2610	gluconate transmembrane transporter activity
HV240_RS00140	COG0583	DNA-binding transcription factor activity
HV240_RS00150	COG2814	Major facilitator Superfamily
HV240_RS00175	COG0028	Belongs to the TPP enzyme family
HV240_RS00180	COG0440	acetolactate synthase activity
HV240_RS00190	COG2197	response regulator
HV240_RS00200	COG2271	Major facilitator Superfamily
HV240_RS00230	COG4580	involved in the transport of maltose and maltodextrins
HV240_RS00235	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV240_RS00240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV240_RS00240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV240_RS00250	COG1609	Transcriptional regulator
HV240_RS00260	COG5464	transposase or invertase
HV240_RS00270	COG0697	spore germination
HV240_RS00275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV240_RS00275	COG1263	PTS System
HV240_RS00285	COG2814	Major facilitator Superfamily
HV240_RS00295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV240_RS00300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV240_RS00310	COG1309	transcriptional regulator
HV240_RS00320	COG0583	DNA-binding transcription factor activity
HV240_RS00335	COG1464	Belongs to the NlpA lipoprotein family
HV240_RS00350	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HV240_RS00375	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HV240_RS00445	COG0582	viral genome integration into host DNA
HV240_RS00455	COG2211	Major facilitator Superfamily
HV240_RS00460	COG1501	Belongs to the glycosyl hydrolase 31 family
HV240_RS00465	COG3711	transcriptional antiterminator
HV240_RS00470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV240_RS00470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV240_RS00470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS00475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV240_RS00480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV240_RS00480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV240_RS00495	COG1940	carbohydrate kinase activity
HV240_RS00510	COG1486	melibiose metabolic process
HV240_RS00515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV240_RS00515	COG1263	PTS System
HV240_RS00525	COG2233	PERMEase
HV240_RS00530	COG0786	glutamate:sodium symporter activity
HV240_RS00545	COG3074	FtsZ-dependent cytokinesis
HV240_RS00560	COG2211	Major facilitator Superfamily
HV240_RS00565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV240_RS00575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV240_RS00595	COG3152	Membrane
HV240_RS00605	COG1494	fructose-1,6-bisphosphatase
HV240_RS00610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HV240_RS00615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV240_RS00620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV240_RS00640	COG2860	membrane
HV240_RS00650	COG1561	YicC-like family, N-terminal region
HV240_RS00660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HV240_RS00675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HV240_RS00685	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HV240_RS00690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HV240_RS00695	COG4245	von Willebrand factor, type A
HV240_RS00730	COG1519	Transferase
HV240_RS00735	COG1216	Glycosyl transferase, family 2
HV240_RS00740	COG0438	transferase activity, transferring glycosyl groups
HV240_RS00750	COG0859	PFAM glycosyl transferase family 9
HV240_RS00775	COG0859	PFAM glycosyl transferase family 9
HV240_RS00780	COG0859	PFAM glycosyl transferase family 9
HV240_RS00800	COG0463	Glycosyl transferase, family 2
HV240_RS00805	COG2861	carbohydrate metabolic process
HV240_RS00810	COG4942	peptidase
HV240_RS00820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV240_RS00825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV240_RS00845	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HV240_RS00855	COG2186	Transcriptional regulator
HV240_RS00875	COG3722	fumarate hydratase activity
HV240_RS00895	COG1566	PFAM secretion protein HlyD family protein
HV240_RS00900	COG0625	glutathione transferase activity
HV240_RS00910	COG3276	selenocysteine insertion sequence binding
HV240_RS00920	COG2211	Major facilitator Superfamily
HV240_RS00925	COG1917	Cupin 2, conserved barrel domain protein
HV240_RS00925	COG4977	sequence-specific DNA binding
HV240_RS00930	COG0235	Class ii aldolase
HV240_RS00935	COG3623	hexulose-6-phosphate isomerase
HV240_RS00940	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HV240_RS00945	COG1070	Carbohydrate kinase
HV240_RS00965	COG2731	YhcH YjgK YiaL family protein
HV240_RS00970	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV240_RS00975	COG1414	Transcriptional regulator
HV240_RS00980	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV240_RS00985	COG3977	Valine--pyruvate aminotransferase
HV240_RS00990	COG0366	Alpha amylase catalytic
HV240_RS00995	COG2992	FlgJ-related protein
HV240_RS01000	COG2207	Transcriptional regulator
HV240_RS01000	COG1609	Transcriptional regulator
HV240_RS01005	COG4214	carbohydrate transport
HV240_RS01015	COG4213	ABC transporter substrate-binding protein
HV240_RS01020	COG2115	Belongs to the xylose isomerase family
HV240_RS01025	COG1070	Carbohydrate kinase
HV240_RS01030	COG4682	membrane
HV240_RS01035	COG3274	enterobacterial common antigen metabolic process
HV240_RS01065	COG1278	Cold shock
HV240_RS01070	COG2944	sequence-specific DNA binding
HV240_RS01075	COG2814	Major facilitator Superfamily
HV240_RS01095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV240_RS01105	COG1609	Transcriptional regulator
HV240_RS01110	COG2885	chlorophyll binding
HV240_RS01115	COG0243	molybdopterin cofactor binding
HV240_RS01120	COG0456	acetyltransferase
HV240_RS01125	COG2818	Glycosylase
HV240_RS01135	COG2223	nitrite transmembrane transporter activity
HV240_RS01150	COG0747	negative chemotaxis
HV240_RS01155	COG0601	transmembrane transport
HV240_RS01160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV240_RS01165	COG0444	Belongs to the ABC transporter superfamily
HV240_RS01170	COG4608	Belongs to the ABC transporter superfamily
HV240_RS01180	COG0489	protein tyrosine kinase activity
HV240_RS01195	COG0457	Tetratricopeptide repeat
HV240_RS01220	COG2194	sulfuric ester hydrolase activity
HV240_RS01250	COG1215	transferase activity, transferring glycosyl groups
HV240_RS01255	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HV240_RS01260	COG3118	belongs to the thioredoxin family
HV240_RS01260	COG0457	Tetratricopeptide repeat
HV240_RS01265	COG2199	diguanylate cyclase activity
HV240_RS01265	COG2200	EAL domain
HV240_RS01275	COG0612	Peptidase, M16
HV240_RS01285	COG2982	Protein involved in outer membrane biogenesis
HV240_RS01290	COG0477	Major facilitator Superfamily
HV240_RS01295	COG1295	ribonuclease BN
HV240_RS01300	COG0583	DNA-binding transcription factor activity
HV240_RS01305	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS01310	COG2197	response regulator
HV240_RS01330	COG1454	alcohol dehydrogenase
HV240_RS01340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV240_RS01345	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HV240_RS01350	COG0671	phosphoesterase, PA-phosphatase related
HV240_RS01355	COG2205	protein histidine kinase activity
HV240_RS01360	COG0745	RESPONSE REGULATOR receiver
HV240_RS01365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV240_RS01370	COG2183	response to ionizing radiation
HV240_RS01380	COG1918	ferrous iron import across plasma membrane
HV240_RS01405	COG1040	competence protein
HV240_RS01415	COG2610	gluconate transmembrane transporter activity
HV240_RS01440	COG1959	2 iron, 2 sulfur cluster binding
HV240_RS01450	COG0589	response to stress
HV240_RS01460	COG0306	phosphate transporter
HV240_RS01465	COG2081	HI0933 family
HV240_RS01475	COG3039	Transposase
HV240_RS01485	COG3964	amidohydrolase
HV240_RS01490	COG0471	metal ion transport
HV240_RS01495	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HV240_RS01500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV240_RS01510	COG2239	Acts as a magnesium transporter
HV240_RS01525	COG0444	Belongs to the ABC transporter superfamily
HV240_RS01530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV240_RS01535	COG0601	transmembrane transport
HV240_RS01540	COG0747	negative chemotaxis
HV240_RS01550	COG3479	Phenolic acid decarboxylase
HV240_RS01590	COG0628	permease
HV240_RS01595	COG0477	Major facilitator Superfamily
HV240_RS01605	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HV240_RS01620	COG3714	YhhN family
HV240_RS01630	COG3776	membrane
HV240_RS01635	COG0742	ribosomal rna small subunit methyltransferase
HV240_RS01640	COG0552	protein localization to endoplasmic reticulum
HV240_RS01645	COG2884	Cell division ATP-binding protein ftsE
HV240_RS01650	COG2177	Part of the ABC transporter FtsEX involved in
HV240_RS01665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV240_RS01680	COG0683	leucine binding
HV240_RS01715	COG2721	sulfolactate sulfo-lyase activity
HV240_RS01720	COG2271	Major facilitator Superfamily
HV240_RS01725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV240_RS01730	COG1414	Transcriptional regulator
HV240_RS01755	COG0584	glycerophosphoryl diester phosphodiesterase
HV240_RS01765	COG0405	Gamma-glutamyltransferase
HV240_RS01770	COG1247	-acetyltransferase
HV240_RS01780	COG0673	inositol 2-dehydrogenase activity
HV240_RS01785	COG1741	Belongs to the pirin family
HV240_RS01790	COG1609	Transcriptional regulator
HV240_RS01795	COG3265	gluconokinase activity
HV240_RS01800	COG2610	gluconate transmembrane transporter activity
HV240_RS01815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV240_RS01840	COG0058	SHG alpha-glucan phosphorylase activity
HV240_RS01845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV240_RS01860	COG1349	DNA-binding transcription factor activity
HV240_RS01870	COG0058	SHG alpha-glucan phosphorylase activity
HV240_RS01875	COG1640	4-alpha-glucanotransferase
HV240_RS01890	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HV240_RS01895	COG1011	Hydrolase
HV240_RS01905	COG0494	nUDIX hydrolase
HV240_RS01910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HV240_RS01920	COG3166	PFAM Fimbrial assembly family protein
HV240_RS01935	COG4796	Type ii and iii secretion system protein
HV240_RS01950	COG3266	domain, Protein
HV240_RS01955	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV240_RS01960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV240_RS01985	COG2146	nitrite reductase [NAD(P)H] activity
HV240_RS01990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV240_RS01995	COG0402	S-adenosylhomocysteine deaminase activity
HV240_RS02000	COG0738	Major facilitator superfamily
HV240_RS02025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HV240_RS02030	COG1289	transmembrane transporter activity
HV240_RS02040	COG1765	OsmC-like protein
HV240_RS02045	COG3954	Phosphoribulokinase
HV240_RS02055	COG0429	hydrolase of the alpha beta-hydrolase fold
HV240_RS02065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HV240_RS02075	COG0488	(ABC) transporter
HV240_RS02090	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HV240_RS02095	COG1047	Peptidyl-prolyl cis-trans
HV240_RS02105	COG0545	Peptidyl-prolyl cis-trans isomerase
HV240_RS02110	COG2964	Protein conserved in bacteria
HV240_RS02165	COG0051	transcription antitermination factor activity, RNA binding
HV240_RS02175	COG0088	Forms part of the polypeptide exit tunnel
HV240_RS02190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HV240_RS02205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HV240_RS02255	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HV240_RS02270	COG0201	protein transport
HV240_RS02285	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HV240_RS02295	COG0202	RNA polymerase activity
HV240_RS02300	COG0203	ribosomal protein L17
HV240_RS02310	COG0789	Transcriptional regulator
HV240_RS02315	COG3036	rescue of stalled ribosome
HV240_RS02345	COG0758	DNA mediated transformation
HV240_RS02355	COG0551	DNA topoisomerase type I activity
HV240_RS02375	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV240_RS02415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV240_RS02420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV240_RS02425	COG1309	transcriptional regulator
HV240_RS02450	COG4145	pantothenate transmembrane transporter activity
HV240_RS02455	COG3924	membrane
HV240_RS02460	COG0439	Biotin carboxylase
HV240_RS02465	COG0511	ligase activity, forming carbon-carbon bonds
HV240_RS02480	COG0604	alcohol dehydrogenase
HV240_RS02485	COG2200	EAL domain
HV240_RS02485	COG2199	diguanylate cyclase activity
HV240_RS02490	COG1077	Cell shape determining protein MreB Mrl
HV240_RS02495	COG1792	Involved in formation and maintenance of cell shape
HV240_RS02500	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HV240_RS02510	COG1530	ribonuclease E activity
HV240_RS02515	COG3164	Protein of unknown function
HV240_RS02520	COG0312	modulator of DNA gyrase
HV240_RS02525	COG1349	DNA-binding transcription factor activity
HV240_RS02530	COG0583	DNA-binding transcription factor activity
HV240_RS02545	COG1289	transmembrane transporter activity
HV240_RS02550	COG2732	(Barnase) inhibitor
HV240_RS02575	COG2188	Transcriptional regulator
HV240_RS02585	COG0471	metal ion transport
HV240_RS02590	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV240_RS02595	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV240_RS02620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV240_RS02625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV240_RS02630	COG3105	Protein conserved in bacteria
HV240_RS02635	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HV240_RS02650	COG0625	glutathione transferase activity
HV240_RS02655	COG2969	positive regulation of protein catabolic process
HV240_RS02665	COG0493	'glutamate synthase
HV240_RS02670	COG0067	glutamate synthase
HV240_RS02670	COG0069	glutamate synthase activity
HV240_RS02670	COG0070	glutamate synthase
HV240_RS02675	COG1242	4 iron, 4 sulfur cluster binding
HV240_RS02680	COG0784	Response regulator, receiver
HV240_RS02680	COG2198	Histidine kinase
HV240_RS02680	COG5002	protein histidine kinase activity
HV240_RS02685	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HV240_RS02690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HV240_RS02695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS02700	COG1660	Displays ATPase and GTPase activities
HV240_RS02705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS02710	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV240_RS02715	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HV240_RS02720	COG1137	ATPase activity
HV240_RS02725	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HV240_RS02730	COG3117	lipopolysaccharide transmembrane transporter activity
HV240_RS02735	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HV240_RS02745	COG0530	calcium, potassium:sodium antiporter activity
HV240_RS02750	COG1127	ABC transporter
HV240_RS02755	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV240_RS02760	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV240_RS02765	COG2854	intermembrane phospholipid transfer
HV240_RS02770	COG3113	response to antibiotic
HV240_RS02775	COG5007	Belongs to the BolA IbaG family
HV240_RS02785	COG3423	Transcriptional regulator
HV240_RS02790	COG0142	geranyltranstransferase activity
HV240_RS02805	COG0697	spore germination
HV240_RS02815	COG2027	D-alanyl-D-alanine carboxypeptidase
HV240_RS02825	COG1534	Rna-binding protein
HV240_RS02835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HV240_RS02840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HV240_RS02850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HV240_RS02875	COG0195	Participates in both transcription termination and antitermination
HV240_RS02880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HV240_RS02915	COG0513	Belongs to the DEAD box helicase family
HV240_RS02920	COG0814	amino acid
HV240_RS02945	COG0511	ligase activity, forming carbon-carbon bonds
HV240_RS02990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV240_RS02995	COG0826	peptidase U32
HV240_RS03000	COG0826	peptidase U32
HV240_RS03005	COG3154	lipid carrier protein
HV240_RS03010	COG3153	acetyltransferase
HV240_RS03015	COG2827	Endonuclease containing a URI domain
HV240_RS03025	COG0693	protein deglycase activity
HV240_RS03030	COG0702	epimerase
HV240_RS03035	COG0701	Predicted permease
HV240_RS03040	COG2823	Periplasmic or secreted lipoprotein
HV240_RS03060	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HV240_RS03075	COG1063	alcohol dehydrogenase
HV240_RS03080	COG3775	system Galactitol-specific IIC component
HV240_RS03085	COG3414	Phosphotransferase system galactitol-specific IIB component
HV240_RS03090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS03095	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
HV240_RS03100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS03100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS03105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV240_RS03105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS03105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV240_RS03115	COG0191	fructose-bisphosphate aldolase activity
HV240_RS03120	COG1349	DNA-binding transcription factor activity
HV240_RS03125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV240_RS03130	COG2721	sulfolactate sulfo-lyase activity
HV240_RS03135	COG2271	Major facilitator Superfamily
HV240_RS03145	COG2084	Dehydrogenase
HV240_RS03150	COG1929	Belongs to the glycerate kinase type-1 family
HV240_RS03170	COG1741	Belongs to the pirin family
HV240_RS03175	COG0583	DNA-binding transcription factor activity
HV240_RS03180	COG3152	Membrane
HV240_RS03185	COG0435	Glutathione S-transferase
HV240_RS03190	COG2259	Doxx family
HV240_RS03200	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HV240_RS03205	COG4575	ribosome binding
HV240_RS03210	COG1422	Protein of unknown function (DUF1090)
HV240_RS03220	COG0586	Pfam SNARE associated Golgi protein
HV240_RS03225	COG2186	Transcriptional regulator
HV240_RS03230	COG2271	Major facilitator Superfamily
HV240_RS03240	COG2721	sulfolactate sulfo-lyase activity
HV240_RS03260	COG0673	inositol 2-dehydrogenase activity
HV240_RS03265	COG1451	nucleotide metabolic process
HV240_RS03270	COG3507	Belongs to the glycosyl hydrolase 43 family
HV240_RS03280	COG2211	Major facilitator Superfamily
HV240_RS03290	COG1902	pentaerythritol trinitrate reductase activity
HV240_RS03290	COG0446	pyridine nucleotide-disulphide oxidoreductase
HV240_RS03310	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS03340	COG1695	Transcriptional regulator
HV240_RS03345	COG2375	cellular response to nickel ion
HV240_RS03360	COG1461	Dihydroxyacetone kinase
HV240_RS03365	COG2376	Dihydroxyacetone kinase
HV240_RS03385	COG0582	viral genome integration into host DNA
HV240_RS03485	COG1802	Transcriptional regulator
HV240_RS03485	COG4626	Terminase
HV240_RS03520	COG0358	DNA primase activity
HV240_RS03525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HV240_RS03580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV240_RS03595	COG4991	sh3 domain protein
HV240_RS03600	COG3025	triphosphatase activity
HV240_RS03625	COG2960	long-chain fatty acid transporting porin activity
HV240_RS03635	COG3539	Fimbrial protein
HV240_RS03640	COG3121	Chaperone
HV240_RS03645	COG3188	usher protein
HV240_RS03650	COG3539	Fimbrial protein
HV240_RS03660	COG3384	dioxygenase
HV240_RS03665	COG0754	glutathionylspermidine amidase activity
HV240_RS03680	COG0494	nUDIX hydrolase
HV240_RS03685	COG3151	Protein conserved in bacteria
HV240_RS03690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HV240_RS03695	COG3150	esterase
HV240_RS03700	COG0187	DNA topoisomerase II activity
HV240_RS03715	COG2211	Major facilitator Superfamily
HV240_RS03720	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV240_RS03725	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HV240_RS03730	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV240_RS03735	COG0642	Histidine kinase
HV240_RS03745	COG3111	PFAM Bacterial OB fold (BOF) protein
HV240_RS03755	COG0204	Acyl-transferase
HV240_RS03760	COG2132	Multicopper oxidase
HV240_RS03765	COG1032	radical SAM domain protein
HV240_RS03775	COG1979	alcohol dehydrogenase
HV240_RS03780	COG2207	Transcriptional regulator
HV240_RS03785	COG0586	Pfam SNARE associated Golgi protein
HV240_RS03800	COG0848	biopolymer transport protein
HV240_RS03820	COG0625	glutathione transferase activity
HV240_RS03830	COG0754	glutathionylspermidine amidase activity
HV240_RS03835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV240_RS03860	COG0626	cystathionine gamma-synthase activity
HV240_RS03870	COG0471	metal ion transport
HV240_RS03880	COG1811	Na channel or pump
HV240_RS03885	COG1982	Orn Lys Arg decarboxylase major
HV240_RS03890	COG2211	Major facilitator Superfamily
HV240_RS03905	COG1194	a g-specific adenine glycosylase
HV240_RS03915	COG3171	Protein conserved in bacteria
HV240_RS03930	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HV240_RS03935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HV240_RS03940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV240_RS03955	COG0762	integral membrane protein
HV240_RS03960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HV240_RS03965	COG2805	Type II/IV secretion system protein
HV240_RS03970	COG2197	response regulator
HV240_RS03990	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HV240_RS03995	COG2356	endonuclease I
HV240_RS04005	COG2814	Major facilitator Superfamily
HV240_RS04025	COG1166	arginine decarboxylase activity
HV240_RS04035	COG0501	Belongs to the peptidase M48B family
HV240_RS04040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV240_RS04045	COG1122	ATPase activity
HV240_RS04065	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HV240_RS04070	COG5301	cellulose 1,4-beta-cellobiosidase activity
HV240_RS04120	COG4386	tail sheath protein
HV240_RS04145	COG4397	Mu-like prophage major head subunit gpT
HV240_RS04165	COG2369	cell adhesion
HV240_RS04170	COG4383	Mu-like prophage protein gp29
HV240_RS04220	COG3179	chitinase
HV240_RS04255	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HV240_RS04290	COG2842	Transposition protein
HV240_RS04300	COG3423	Transcriptional regulator
HV240_RS04340	COG0191	fructose-bisphosphate aldolase activity
HV240_RS04345	COG0668	transmembrane transport
HV240_RS04355	COG2968	Membrane
HV240_RS04360	COG0583	DNA-binding transcription factor activity
HV240_RS04365	COG0427	acetyl-CoA hydrolase
HV240_RS04370	COG1024	Enoyl-CoA hydratase
HV240_RS04375	COG1703	isobutyryl-CoA mutase activity
HV240_RS04380	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV240_RS04380	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV240_RS04395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV240_RS04400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HV240_RS04420	COG0006	proline dipeptidase activity
HV240_RS04425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV240_RS04430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV240_RS04450	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS04455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HV240_RS04460	COG2723	6-phospho-beta-galactosidase activity
HV240_RS04465	COG1737	Transcriptional regulator
HV240_RS04475	COG1272	protein, Hemolysin III
HV240_RS04485	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HV240_RS04495	COG0716	FMN binding
HV240_RS04510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HV240_RS04530	COG1811	Na channel or pump
HV240_RS04540	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV240_RS04545	COG0583	DNA-binding transcription factor activity
HV240_RS04550	COG4942	peptidase
HV240_RS04560	COG0582	viral genome integration into host DNA
HV240_RS04580	COG0702	epimerase
HV240_RS04590	COG0667	Aldo Keto reductase
HV240_RS04595	COG0656	L-ascorbic acid biosynthetic process
HV240_RS04610	COG3775	system Galactitol-specific IIC component
HV240_RS04615	COG1070	Carbohydrate kinase
HV240_RS04625	COG2188	Transcriptional regulator
HV240_RS04645	COG1063	alcohol dehydrogenase
HV240_RS04675	COG5002	protein histidine kinase activity
HV240_RS04685	COG0667	Aldo Keto reductase
HV240_RS04695	COG0778	Nitroreductase
HV240_RS04700	COG2814	Major facilitator Superfamily
HV240_RS04735	COG3596	GTP binding
HV240_RS04750	COG2003	Belongs to the UPF0758 family
HV240_RS04775	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV240_RS04790	COG2223	nitrite transmembrane transporter activity
HV240_RS04795	COG3835	regulator
HV240_RS04800	COG1929	Belongs to the glycerate kinase type-1 family
HV240_RS04845	COG0738	Major facilitator superfamily
HV240_RS04850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV240_RS04855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV240_RS04860	COG1349	DNA-binding transcription factor activity
HV240_RS04890	COG1312	Catalyzes the dehydration of D-mannonate
HV240_RS04895	COG3104	oligopeptide transport
HV240_RS04905	COG2909	trisaccharide binding
HV240_RS04910	COG1538	Outer membrane efflux protein
HV240_RS04915	COG1289	transmembrane transporter activity
HV240_RS04930	COG3592	Divergent 4Fe-4S mono-cluster
HV240_RS04935	COG2388	GCN5-related N-acetyl-transferase
HV240_RS04945	COG3539	Fimbrial protein
HV240_RS04950	COG3539	Fimbrial protein
HV240_RS04955	COG3539	Fimbrial protein
HV240_RS04960	COG3188	usher protein
HV240_RS04965	COG3121	Chaperone
HV240_RS04970	COG3539	Fimbrial protein
HV240_RS04980	COG4974	Belongs to the 'phage' integrase family
HV240_RS04985	COG0582	viral genome integration into host DNA
HV240_RS05000	COG1522	sequence-specific DNA binding
HV240_RS05005	COG1846	Transcriptional regulator
HV240_RS05010	COG0697	spore germination
HV240_RS05025	COG0640	Transcriptional regulator
HV240_RS05070	COG0667	Aldo Keto reductase
HV240_RS05075	COG0814	amino acid
HV240_RS05090	COG0183	Belongs to the thiolase family
HV240_RS05100	COG0823	Involved in the tonB-independent uptake of proteins
HV240_RS05105	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS05110	COG2814	Major facilitator Superfamily
HV240_RS05135	COG0823	Involved in the tonB-independent uptake of proteins
HV240_RS05145	COG3842	ATPase activity
HV240_RS05150	COG0395	ABC-type sugar transport system, permease component
HV240_RS05155	COG1175	transmembrane transport
HV240_RS05165	COG1794	racemase activity, acting on amino acids and derivatives
HV240_RS05170	COG0583	DNA-binding transcription factor activity
HV240_RS05180	COG1609	Transcriptional regulator
HV240_RS05185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV240_RS05190	COG2723	6-phospho-beta-galactosidase activity
HV240_RS05195	COG2186	Transcriptional regulator
HV240_RS05205	COG1609	Transcriptional regulator
HV240_RS05220	COG0667	Aldo Keto reductase
HV240_RS05230	COG0861	Integral membrane protein TerC family
HV240_RS05265	COG2165	general secretion pathway protein
HV240_RS05270	COG4795	General secretion pathway protein
HV240_RS05280	COG4967	type IV pilus modification protein PilV
HV240_RS05285	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HV240_RS05290	COG1025	Belongs to the peptidase M16 family
HV240_RS05295	COG1074	ATP-dependent DNA helicase activity
HV240_RS05300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HV240_RS05305	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HV240_RS05305	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HV240_RS05310	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV240_RS05315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HV240_RS05345	COG4656	Part of a membrane complex involved in electron transport
HV240_RS05350	COG1454	alcohol dehydrogenase
HV240_RS05380	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HV240_RS05545	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HV240_RS05550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HV240_RS05555	COG2166	iron-sulfur cluster assembly
HV240_RS05560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HV240_RS05570	COG0583	DNA-binding transcription factor activity
HV240_RS05575	COG2363	Small membrane protein
HV240_RS05585	COG1349	DNA-binding transcription factor activity
HV240_RS05605	COG0738	Major facilitator superfamily
HV240_RS05610	COG0235	Class ii aldolase
HV240_RS05625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV240_RS05640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV240_RS05645	COG1760	l-serine dehydratase
HV240_RS05650	COG0814	amino acid
HV240_RS05655	COG1611	Belongs to the LOG family
HV240_RS05675	COG3098	single-species biofilm formation
HV240_RS05680	COG0564	pseudouridine synthase activity
HV240_RS05685	COG0716	FMN binding
HV240_RS05690	COG2271	Major facilitator Superfamily
HV240_RS05695	COG4948	Mandelate Racemase Muconate Lactonizing
HV240_RS05700	COG4948	Mandelate Racemase Muconate Lactonizing
HV240_RS05705	COG1929	Belongs to the glycerate kinase type-1 family
HV240_RS05710	COG4999	Histidine kinase
HV240_RS05710	COG2205	protein histidine kinase activity
HV240_RS05710	COG3437	response regulator, receiver
HV240_RS05710	COG3850	Histidine kinase
HV240_RS05720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV240_RS05725	COG3956	TIGRFAM MazG family protein
HV240_RS05745	COG0602	queuosine metabolic process
HV240_RS05750	COG0720	synthase
HV240_RS05775	COG2234	aminopeptidase activity
HV240_RS05835	COG1388	LysM domain
HV240_RS05835	COG4942	peptidase
HV240_RS05840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HV240_RS05870	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV240_RS05890	COG3539	Fimbrial protein
HV240_RS05900	COG3188	usher protein
HV240_RS05905	COG3121	Chaperone
HV240_RS05915	COG3539	Fimbrial protein
HV240_RS05920	COG3539	Fimbrial protein
HV240_RS05945	COG1132	(ABC) transporter
HV240_RS05950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV240_RS05960	COG1538	Outer membrane efflux protein
HV240_RS05965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV240_RS06005	COG1454	alcohol dehydrogenase
HV240_RS06010	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HV240_RS06015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV240_RS06020	COG4558	Periplasmic binding protein
HV240_RS06025	COG3720	iron ion transport
HV240_RS06045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV240_RS06050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV240_RS06055	COG1121	(ABC) transporter
HV240_RS06065	COG1609	Transcriptional regulator
HV240_RS06070	COG1940	carbohydrate kinase activity
HV240_RS06075	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV240_RS06080	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV240_RS06085	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV240_RS06105	COG2723	6-phospho-beta-galactosidase activity
HV240_RS06110	COG2755	lipolytic protein G-D-S-L family
HV240_RS06110	COG0657	acetylesterase activity
HV240_RS06120	COG0309	Hydrogenase expression formation protein (HypE)
HV240_RS06125	COG0409	Hydrogenase expression formation protein
HV240_RS06130	COG0298	carbon dioxide binding
HV240_RS06135	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HV240_RS06150	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV240_RS06155	COG0651	ATP synthesis coupled electron transport
HV240_RS06160	COG0650	Formate hydrogenlyase subunit 4
HV240_RS06165	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HV240_RS06165	COG3261	NADH dehydrogenase
HV240_RS06170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV240_RS06175	COG3260	NADH ubiquinone oxidoreductase 20
HV240_RS06185	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HV240_RS06190	COG2723	6-phospho-beta-galactosidase activity
HV240_RS06195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV240_RS06195	COG1263	PTS System
HV240_RS06200	COG1609	Transcriptional regulator
HV240_RS06205	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV240_RS06210	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HV240_RS06215	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HV240_RS06240	COG1349	DNA-binding transcription factor activity
HV240_RS06245	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS06250	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS06260	COG3732	PTS system glucitol sorbitol-specific
HV240_RS06265	COG3730	PTS system glucitol sorbitol-specific
HV240_RS06270	COG2951	lytic endotransglycosylase activity
HV240_RS06280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV240_RS06285	COG0803	Belongs to the bacterial solute-binding protein 9 family
HV240_RS06290	COG1546	Belongs to the CinA family
HV240_RS06310	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HV240_RS06340	COG2823	Periplasmic or secreted lipoprotein
HV240_RS06345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV240_RS06350	COG1238	metal cluster binding
HV240_RS06370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HV240_RS06375	COG2814	Major facilitator Superfamily
HV240_RS06380	COG1566	PFAM secretion protein HlyD family protein
HV240_RS06385	COG1846	Transcriptional regulator
HV240_RS06395	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV240_RS06400	COG2113	Glycine betaine
HV240_RS06405	COG4176	ABC-type proline glycine betaine transport system permease component
HV240_RS06415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV240_RS06420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV240_RS06430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV240_RS06435	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV240_RS06445	COG4575	ribosome binding
HV240_RS06470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV240_RS06475	COG0640	Transcriptional regulator
HV240_RS06480	COG3284	Transcriptional regulator
HV240_RS06485	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS06515	COG0582	viral genome integration into host DNA
HV240_RS06530	COG2867	negative regulation of translational initiation
HV240_RS06545	COG0497	DNA recombination
HV240_RS06560	COG4536	flavin adenine dinucleotide binding
HV240_RS06565	COG4137	Cytochrome C assembly protein
HV240_RS06570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HV240_RS06605	COG2885	chlorophyll binding
HV240_RS06610	COG2199	diguanylate cyclase activity
HV240_RS06620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV240_RS06625	COG1605	Chorismate mutase
HV240_RS06625	COG0287	Prephenate dehydrogenase
HV240_RS06635	COG1605	Chorismate mutase
HV240_RS06635	COG0077	Prephenate dehydratase
HV240_RS06640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV240_RS06645	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV240_RS06660	COG0542	response to heat
HV240_RS06685	COG0477	Major facilitator Superfamily
HV240_RS06690	COG5544	Lipoprotein
HV240_RS06695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV240_RS06710	COG3118	belongs to the thioredoxin family
HV240_RS06715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV240_RS06730	COG0513	Belongs to the DEAD box helicase family
HV240_RS06740	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HV240_RS06755	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HV240_RS06765	COG3086	response to oxidative stress
HV240_RS06775	COG0681	Belongs to the peptidase S26 family
HV240_RS06795	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HV240_RS06805	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV240_RS06810	COG1737	Transcriptional regulator
HV240_RS06815	COG0560	Phosphoserine phosphatase
HV240_RS06830	COG0047	phosphoribosylformylglycinamidine synthase activity
HV240_RS06830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HV240_RS06835	COG2205	protein histidine kinase activity
HV240_RS06840	COG3170	Tfp pilus assembly protein FimV
HV240_RS06845	COG2204	response regulator
HV240_RS06850	COG0347	Belongs to the P(II) protein family
HV240_RS06865	COG2259	Doxx family
HV240_RS06870	COG1940	carbohydrate kinase activity
HV240_RS06880	COG0477	Major facilitator Superfamily
HV240_RS06880	COG2814	Major facilitator Superfamily
HV240_RS06885	COG2017	converts alpha-aldose to the beta-anomer
HV240_RS06890	COG2814	Major facilitator Superfamily
HV240_RS06895	COG3711	transcriptional antiterminator
HV240_RS06900	COG3683	transport system, periplasmic component
HV240_RS06905	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HV240_RS06930	COG0822	iron-sulfur transferase activity
HV240_RS06950	COG0633	Ferredoxin
HV240_RS06955	COG2975	iron-sulfur cluster assembly
HV240_RS06970	COG2897	thiosulfate sulfurtransferase activity
HV240_RS06975	COG2373	Large extracellular alpha-helical protein
HV240_RS06980	COG4953	penicillin-binding protein 1C
HV240_RS07010	COG2976	Protein conserved in bacteria
HV240_RS07035	COG1645	bacterial-type flagellum-dependent swarming motility
HV240_RS07050	COG1570	exodeoxyribonuclease VII activity
HV240_RS07055	COG0517	IMP dehydrogenase activity
HV240_RS07055	COG0516	GMP reductase activity
HV240_RS07060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HV240_RS07060	COG0519	Catalyzes the synthesis of GMP from XMP
HV240_RS07070	COG0583	DNA-binding transcription factor activity
HV240_RS07090	COG0248	Ppx GppA phosphatase
HV240_RS07120	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HV240_RS07135	COG2723	6-phospho-beta-galactosidase activity
HV240_RS07140	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HV240_RS07145	COG2233	PERMEase
HV240_RS07155	COG1393	Belongs to the ArsC family
HV240_RS07160	COG4783	chaperone-mediated protein folding
HV240_RS07165	COG0628	permease
HV240_RS07170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HV240_RS07175	COG2716	regulation of RNA biosynthetic process
HV240_RS07185	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HV240_RS07195	COG2321	neutral zinc metallopeptidase
HV240_RS07205	COG0400	carboxylic ester hydrolase activity
HV240_RS07220	COG1393	Belongs to the ArsC family
HV240_RS07230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV240_RS07235	COG0493	'glutamate synthase
HV240_RS07235	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV240_RS07245	COG5342	invasion associated locus B
HV240_RS07250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV240_RS07260	COG4810	utilization protein
HV240_RS07270	COG4766	ethanolamine catabolic process
HV240_RS07340	COG2207	Transcriptional regulator
HV240_RS07350	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV240_RS07370	COG2837	iron assimilation
HV240_RS07375	COG4150	thiosulfate binding
HV240_RS07380	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HV240_RS07385	COG4208	sulfate ABC transporter
HV240_RS07390	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HV240_RS07400	COG4319	ketosteroid isomerase
HV240_RS07440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HV240_RS07460	COG3530	Putative quorum-sensing-regulated virulence factor
HV240_RS07465	COG0385	Bile acid
HV240_RS07470	COG0583	DNA-binding transcription factor activity
HV240_RS07475	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HV240_RS07480	COG2211	Major facilitator Superfamily
HV240_RS07485	COG0583	DNA-binding transcription factor activity
HV240_RS07515	COG3415	Transposase
HV240_RS07520	COG3415	Transposase
HV240_RS07550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV240_RS07565	COG0667	Aldo Keto reductase
HV240_RS07570	COG3961	Belongs to the TPP enzyme family
HV240_RS07585	COG3279	Response regulator of the LytR AlgR family
HV240_RS07590	COG3275	phosphorelay sensor kinase activity
HV240_RS07595	COG0436	Aminotransferase
HV240_RS07615	COG2116	formate transmembrane transporter activity
HV240_RS07630	COG3691	Protein conserved in bacteria
HV240_RS07645	COG2062	phosphohistidine phosphatase, SixA
HV240_RS07670	COG0730	response to heat
HV240_RS07675	COG3101	peptidyl-lysine hydroxylation
HV240_RS07690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV240_RS07710	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV240_RS07720	COG0586	Pfam SNARE associated Golgi protein
HV240_RS07730	COG0285	dihydrofolate synthase activity
HV240_RS07735	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HV240_RS07740	COG1286	toxin biosynthetic process
HV240_RS07745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HV240_RS07750	COG0163	prenyltransferase activity
HV240_RS07770	COG4160	amino acid transport
HV240_RS07775	COG4598	ABC transporter
HV240_RS07795	COG1090	epimerase
HV240_RS07800	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV240_RS07805	COG0625	glutathione transferase activity
HV240_RS07810	COG0625	glutathione transferase activity
HV240_RS07815	COG0622	Phosphoesterase
HV240_RS07825	COG1609	Transcriptional regulator
HV240_RS07830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS07840	COG3037	sugar-specific permease SgaT UlaA
HV240_RS07845	COG3959	Transketolase, thiamine diphosphate binding domain
HV240_RS07850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HV240_RS07875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV240_RS07880	COG0471	metal ion transport
HV240_RS07880	COG0490	domain, Protein
HV240_RS07890	COG0436	Aminotransferase
HV240_RS07895	COG0583	DNA-binding transcription factor activity
HV240_RS07940	COG0839	Belongs to the complex I subunit 6 family
HV240_RS07945	COG0713	ATP synthesis coupled electron transport
HV240_RS07950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HV240_RS07955	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV240_RS07965	COG0582	viral genome integration into host DNA
HV240_RS07995	COG0582	viral genome integration into host DNA
HV240_RS08005	COG2153	protein acetylation
HV240_RS08010	COG1169	isochorismate synthase
HV240_RS08040	COG3647	Membrane
HV240_RS08065	COG0642	Histidine kinase
HV240_RS08095	COG1414	Transcriptional regulator
HV240_RS08105	COG2271	Major facilitator Superfamily
HV240_RS08115	COG0247	lactate metabolic process
HV240_RS08125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV240_RS08130	COG2271	Major facilitator Superfamily
HV240_RS08135	COG0584	glycerophosphoryl diester phosphodiesterase
HV240_RS08140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV240_RS08165	COG2205	protein histidine kinase activity
HV240_RS08165	COG0784	Response regulator, receiver
HV240_RS08175	COG0642	Histidine kinase
HV240_RS08175	COG2198	Histidine kinase
HV240_RS08190	COG2169	Transcriptional regulator
HV240_RS08190	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HV240_RS08200	COG4615	Cyclic peptide transporter
HV240_RS08205	COG2239	Acts as a magnesium transporter
HV240_RS08210	COG0659	secondary active sulfate transmembrane transporter activity
HV240_RS08230	COG0628	permease
HV240_RS08325	COG0582	viral genome integration into host DNA
HV240_RS08350	COG1349	DNA-binding transcription factor activity
HV240_RS08355	COG0494	nUDIX hydrolase
HV240_RS08365	COG1061	Type III restriction enzyme res subunit
HV240_RS08370	COG1187	pseudouridine synthase activity
HV240_RS08375	COG2814	Major facilitator Superfamily
HV240_RS08385	COG4172	Belongs to the ABC transporter superfamily
HV240_RS08390	COG4239	(ABC) transporter, permease
HV240_RS08395	COG4174	ABC transporter (Permease)
HV240_RS08400	COG4166	transmembrane transport
HV240_RS08405	COG2200	EAL domain
HV240_RS08410	COG0791	NLP P60 protein
HV240_RS08415	COG0671	phosphoesterase, PA-phosphatase related
HV240_RS08420	COG0523	cobalamin synthesis protein
HV240_RS08425	COG0246	Mannitol dehydrogenase
HV240_RS08430	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HV240_RS08440	COG2814	Major facilitator Superfamily
HV240_RS08445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS08445	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS08450	COG1105	Belongs to the carbohydrate kinase PfkB family
HV240_RS08455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV240_RS08455	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HV240_RS08455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV240_RS08460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV240_RS08465	COG2313	pseudouridylate synthase activity
HV240_RS08470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV240_RS08475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV240_RS08475	COG1522	sequence-specific DNA binding
HV240_RS08485	COG2855	membrane
HV240_RS08490	COG0583	DNA-binding transcription factor activity
HV240_RS08495	COG0833	amino acid
HV240_RS08500	COG4771	TonB-dependent receptor
HV240_RS08515	COG2311	Membrane
HV240_RS08530	COG1129	ABC transporter
HV240_RS08555	COG2949	membrane
HV240_RS08565	COG1346	cytolysis
HV240_RS08575	COG0583	DNA-binding transcription factor activity
HV240_RS08580	COG2271	Major facilitator Superfamily
HV240_RS08595	COG0625	glutathione transferase activity
HV240_RS08600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV240_RS08605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV240_RS08610	COG3711	transcriptional antiterminator
HV240_RS08620	COG2723	6-phospho-beta-galactosidase activity
HV240_RS08625	COG2226	methyltransferase
HV240_RS08630	COG1538	Outer membrane efflux protein
HV240_RS08635	COG0586	Pfam SNARE associated Golgi protein
HV240_RS08645	COG1686	Belongs to the peptidase S11 family
HV240_RS08655	COG0277	FAD linked oxidase domain protein
HV240_RS08660	COG1472	Belongs to the glycosyl hydrolase 3 family
HV240_RS08665	COG1732	Glycine betaine
HV240_RS08670	COG1174	glycine betaine transport
HV240_RS08675	COG1125	glycine betaine transport
HV240_RS08680	COG1174	glycine betaine transport
HV240_RS08690	COG0789	Transcriptional regulator
HV240_RS08695	COG3275	phosphorelay sensor kinase activity
HV240_RS08705	COG4807	Protein conserved in bacteria
HV240_RS08710	COG4808	Protein conserved in bacteria
HV240_RS08715	COG4715	Zinc finger, swim domain protein
HV240_RS08720	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HV240_RS08725	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HV240_RS08730	COG0714	Associated with various cellular activities
HV240_RS08735	COG3831	ATPase activity
HV240_RS08740	COG3831	ATPase activity
HV240_RS08750	COG0489	protein tyrosine kinase activity
HV240_RS08760	COG5455	response to cobalt ion
HV240_RS08765	COG0583	DNA-binding transcription factor activity
HV240_RS08770	COG2252	PERMEase
HV240_RS08780	COG0583	DNA-binding transcription factor activity
HV240_RS08785	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HV240_RS08830	COG3039	Transposase
HV240_RS08840	COG0351	phosphomethylpyrimidine kinase
HV240_RS08845	COG1830	Aldolase
HV240_RS08875	COG1070	Carbohydrate kinase
HV240_RS08885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV240_RS08895	COG4948	Mandelate Racemase Muconate Lactonizing
HV240_RS08900	COG0747	negative chemotaxis
HV240_RS08905	COG0601	transmembrane transport
HV240_RS08915	COG0444	Belongs to the ABC transporter superfamily
HV240_RS08920	COG4608	Belongs to the ABC transporter superfamily
HV240_RS08945	COG0745	RESPONSE REGULATOR receiver
HV240_RS08950	COG2205	protein histidine kinase activity
HV240_RS08980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV240_RS08995	COG1522	sequence-specific DNA binding
HV240_RS09005	COG2267	carboxylic ester hydrolase activity
HV240_RS09020	COG0601	transmembrane transport
HV240_RS09025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV240_RS09075	COG4608	Belongs to the ABC transporter superfamily
HV240_RS09085	COG1301	dicarboxylic acid transport
HV240_RS09110	COG0243	molybdopterin cofactor binding
HV240_RS09110	COG3383	formate dehydrogenase (NAD+) activity
HV240_RS09115	COG0437	4 iron, 4 sulfur cluster binding
HV240_RS09120	COG2864	formate dehydrogenase
HV240_RS09125	COG0372	Belongs to the citrate synthase family
HV240_RS09130	COG0443	Heat shock 70 kDa protein
HV240_RS09135	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HV240_RS09150	COG2982	Protein involved in outer membrane biogenesis
HV240_RS09155	COG1253	flavin adenine dinucleotide binding
HV240_RS09200	COG0463	Glycosyl transferase, family 2
HV240_RS09225	COG2244	polysaccharide biosynthetic process
HV240_RS09235	COG1215	transferase activity, transferring glycosyl groups
HV240_RS09240	COG1088	dTDP-glucose 4,6-dehydratase activity
HV240_RS09250	COG1091	dTDP-4-dehydrorhamnose reductase activity
HV240_RS09305	COG1216	Glycosyl transferase, family 2
HV240_RS09315	COG0107	imidazoleglycerol-phosphate synthase activity
HV240_RS09325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HV240_RS09340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HV240_RS09355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV240_RS09360	COG0583	DNA-binding transcription factor activity
HV240_RS09370	COG0531	amino acid
HV240_RS09390	COG2205	protein histidine kinase activity
HV240_RS09475	COG0640	Transcriptional regulator
HV240_RS09480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HV240_RS09485	COG2925	Exonuclease
HV240_RS09505	COG1289	transmembrane transporter activity
HV240_RS09525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HV240_RS09535	COG1942	4-Oxalocrotonate Tautomerase
HV240_RS09540	COG0583	DNA-binding transcription factor activity
HV240_RS09545	COG0095	Lipoate-protein ligase
HV240_RS09550	COG0477	Major facilitator Superfamily
HV240_RS09560	COG5001	Diguanylate cyclase
HV240_RS09560	COG3300	MHYT domain
HV240_RS09565	COG3615	Tellurite resistance protein tehB
HV240_RS09575	COG2188	Transcriptional regulator
HV240_RS09580	COG1263	PTS System
HV240_RS09580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV240_RS09595	COG3539	Fimbrial protein
HV240_RS09600	COG3539	Fimbrial protein
HV240_RS09605	COG3539	Fimbrial protein
HV240_RS09610	COG3188	usher protein
HV240_RS09615	COG3121	Chaperone
HV240_RS09620	COG3539	Fimbrial protein
HV240_RS09630	COG2197	response regulator
HV240_RS09650	COG1376	ErfK ybiS ycfS ynhG family protein
HV240_RS09665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HV240_RS09670	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HV240_RS09685	COG0642	Histidine kinase
HV240_RS09700	COG3423	Transcriptional regulator
HV240_RS09720	COG0534	Mate efflux family protein
HV240_RS09730	COG0582	viral genome integration into host DNA
HV240_RS09835	COG2916	Histone family protein nucleoid-structuring protein H-NS
HV240_RS09870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HV240_RS09900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV240_RS09910	COG0589	response to stress
HV240_RS09920	COG2819	hydrolase of the alpha beta superfamily
HV240_RS09940	COG0251	oxidation-reduction process
HV240_RS09970	COG0463	Glycosyl transferase, family 2
HV240_RS09980	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV240_RS09990	COG1418	mRNA catabolic process
HV240_RS09995	COG0270	DNA (cytosine-5-)-methyltransferase activity
HV240_RS10000	COG3727	T/G mismatch-specific endonuclease activity
HV240_RS10005	COG0697	spore germination
HV240_RS10010	COG2354	Protein conserved in bacteria
HV240_RS10015	COG5475	Uncharacterized small protein (DUF2158)
HV240_RS10045	COG0366	Alpha amylase catalytic
HV240_RS10075	COG2197	response regulator
HV240_RS10085	COG2197	response regulator
HV240_RS10115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV240_RS10120	COG3012	SEC-C Motif Domain Protein
HV240_RS10120	COG3318	Belongs to the UPF0149 family
HV240_RS10125	COG0814	amino acid
HV240_RS10140	COG1528	Iron-storage protein
HV240_RS10150	COG0477	Major facilitator Superfamily
HV240_RS10170	COG1528	Iron-storage protein
HV240_RS10180	COG1879	ABC-type sugar transport system periplasmic component
HV240_RS10190	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS10220	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV240_RS10230	COG3102	Protein conserved in bacteria
HV240_RS10250	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HV240_RS10255	COG1801	Protein of unknown function DUF72
HV240_RS10260	COG1335	isochorismatase
HV240_RS10270	COG0494	nUDIX hydrolase
HV240_RS10275	COG0217	transcriptional regulatory protein
HV240_RS10295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV240_RS10305	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HV240_RS10310	COG0739	heme binding
HV240_RS10315	COG1560	Kdo2-lipid A biosynthetic process
HV240_RS10325	COG1737	Transcriptional regulator
HV240_RS10330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HV240_RS10335	COG0129	dihydroxy-acid dehydratase activity
HV240_RS10340	COG0800	Aldolase
HV240_RS10350	COG3141	response to X-ray
HV240_RS10355	COG2979	Protein of unknown function (DUF533)
HV240_RS10360	COG1770	oligopeptidase
HV240_RS10365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV240_RS10375	COG2372	response to copper ion
HV240_RS10380	COG1276	copper resistance
HV240_RS10425	COG2990	Protein conserved in bacteria
HV240_RS10430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HV240_RS10450	COG3008	intermembrane lipid transfer
HV240_RS10455	COG2995	paraquat-inducible protein a
HV240_RS10460	COG1956	GAF domain-containing protein
HV240_RS10480	COG2814	Major facilitator Superfamily
HV240_RS10485	COG1414	Transcriptional regulator
HV240_RS10515	COG0768	penicillin binding
HV240_RS10520	COG2226	methyltransferase
HV240_RS10535	COG3716	PTS system mannose fructose sorbose family IID component
HV240_RS10540	COG3715	PTS system
HV240_RS10545	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS10545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV240_RS10550	COG1253	flavin adenine dinucleotide binding
HV240_RS10555	COG2200	EAL domain
HV240_RS10560	COG1760	l-serine dehydratase
HV240_RS10590	COG1653	transport
HV240_RS10595	COG1175	transmembrane transport
HV240_RS10600	COG0395	ABC-type sugar transport system, permease component
HV240_RS10605	COG3842	ATPase activity
HV240_RS10615	COG0251	oxidation-reduction process
HV240_RS10620	COG1199	ATP-dependent helicase activity
HV240_RS10625	COG1214	PFAM Peptidase M22, glycoprotease
HV240_RS10630	COG3065	identical protein binding
HV240_RS10640	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HV240_RS10650	COG2894	cell division
HV240_RS10665	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV240_RS10695	COG2719	SpoVR family
HV240_RS10715	COG1619	proteins homologs of microcin C7 resistance protein MccF
HV240_RS10740	COG2211	Major facilitator Superfamily
HV240_RS10755	COG2308	Evidence 4 Homologs of previously reported genes of
HV240_RS10780	COG2814	Major facilitator Superfamily
HV240_RS10795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV240_RS10805	COG1174	glycine betaine transport
HV240_RS10820	COG0564	pseudouridine synthase activity
HV240_RS10840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HV240_RS10855	COG2351	hydroxyisourate hydrolase activity
HV240_RS10860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS10860	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS10865	COG2814	Major facilitator Superfamily
HV240_RS10880	COG2068	MobA-Related Protein
HV240_RS10890	COG2233	PERMEase
HV240_RS10905	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV240_RS10910	COG0402	S-adenosylhomocysteine deaminase activity
HV240_RS10915	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV240_RS10915	COG0493	'glutamate synthase
HV240_RS10920	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HV240_RS10920	COG3608	succinylglutamate desuccinylase aspartoacylase
HV240_RS10925	COG0549	Belongs to the carbamate kinase family
HV240_RS10935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV240_RS10940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV240_RS10945	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HV240_RS10955	COG0012	GTP binding
HV240_RS10975	COG0659	secondary active sulfate transmembrane transporter activity
HV240_RS11005	COG2890	protein-(glutamine-N5) methyltransferase activity
HV240_RS11025	COG0387	Pfam Sodium calcium exchanger
HV240_RS11030	COG4572	Cation transport regulator
HV240_RS11035	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HV240_RS11045	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HV240_RS11050	COG3707	response regulator
HV240_RS11055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV240_RS11065	COG1116	anion transmembrane transporter activity
HV240_RS11070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV240_RS11070	COG2146	nitrite reductase [NAD(P)H] activity
HV240_RS11075	COG0243	molybdopterin cofactor binding
HV240_RS11080	COG4932	domain protein
HV240_RS11085	COG2197	response regulator
HV240_RS11090	COG3850	Histidine kinase
HV240_RS11095	COG2223	nitrite transmembrane transporter activity
HV240_RS11100	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV240_RS11105	COG1140	nitrate reductase beta subunit
HV240_RS11110	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV240_RS11115	COG2181	nitrate reductase activity
HV240_RS11120	COG0697	spore germination
HV240_RS11125	COG1522	sequence-specific DNA binding
HV240_RS11145	COG0788	formyltetrahydrofolate deformylase activity
HV240_RS11155	COG1752	Esterase of the alpha-beta hydrolase superfamily
HV240_RS11160	COG0745	RESPONSE REGULATOR receiver
HV240_RS11165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HV240_RS11180	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS11180	COG1454	alcohol dehydrogenase
HV240_RS11185	COG2095	MarC family integral membrane protein
HV240_RS11195	COG0601	transmembrane transport
HV240_RS11200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV240_RS11205	COG0444	Belongs to the ABC transporter superfamily
HV240_RS11215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV240_RS11235	COG2350	Protein conserved in bacteria
HV240_RS11240	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HV240_RS11245	COG3001	Fructosamine kinase
HV240_RS11255	COG1105	Belongs to the carbohydrate kinase PfkB family
HV240_RS11260	COG3137	Salt-induced outer membrane protein
HV240_RS11285	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HV240_RS11300	COG0072	phenylalanine-tRNA ligase activity
HV240_RS11300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HV240_RS11320	COG0386	Belongs to the glutathione peroxidase family
HV240_RS11330	COG0791	NLP P60 protein
HV240_RS11340	COG4256	Hemin uptake protein
HV240_RS11345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV240_RS11355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV240_RS11355	COG0574	Belongs to the PEP-utilizing enzyme family
HV240_RS11365	COG0628	permease
HV240_RS11370	COG0277	FAD linked oxidase domain protein
HV240_RS11370	COG0247	lactate metabolic process
HV240_RS11375	COG2050	protein possibly involved in aromatic compounds catabolism
HV240_RS11380	COG2261	transglycosylase associated protein
HV240_RS11385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV240_RS11400	COG3121	Chaperone
HV240_RS11420	COG0316	Belongs to the HesB IscA family
HV240_RS11425	COG0719	Fe-S assembly protein
HV240_RS11430	COG0396	ATPase activity
HV240_RS11435	COG0719	Fe-S assembly protein
HV240_RS11450	COG1376	ErfK ybiS ycfS ynhG family protein
HV240_RS11480	COG2271	Major facilitator Superfamily
HV240_RS11485	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV240_RS11490	COG1414	Transcriptional regulator
HV240_RS11525	COG2814	Major facilitator Superfamily
HV240_RS11555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV240_RS11560	COG1960	acyl-CoA dehydrogenase activity
HV240_RS11575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV240_RS11580	COG1116	anion transmembrane transporter activity
HV240_RS11585	COG4774	siderophore transport
HV240_RS11595	COG1120	ATPase activity
HV240_RS11600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV240_RS11605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV240_RS11625	COG0765	amino acid transport
HV240_RS11630	COG1126	abc transporter atp-binding protein
HV240_RS11650	COG3383	formate dehydrogenase (NAD+) activity
HV240_RS11655	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV240_RS11665	COG1175	transmembrane transport
HV240_RS11670	COG3842	ATPase activity
HV240_RS11695	COG1278	Cold shock
HV240_RS11700	COG0626	cystathionine gamma-synthase activity
HV240_RS11705	COG1757	Na H antiporter
HV240_RS11725	COG4993	Dehydrogenase
HV240_RS11730	COG4608	Belongs to the ABC transporter superfamily
HV240_RS11735	COG0444	Belongs to the ABC transporter superfamily
HV240_RS11750	COG0747	negative chemotaxis
HV240_RS11765	COG2011	ABC-type metal ion transport system permease component
HV240_RS11780	COG0346	lactoylglutathione lyase activity
HV240_RS11785	COG1349	DNA-binding transcription factor activity
HV240_RS11800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV240_RS11805	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS11810	COG3111	PFAM Bacterial OB fold (BOF) protein
HV240_RS11820	COG4529	Protein conserved in bacteria
HV240_RS11835	COG2323	membrane
HV240_RS11840	COG1546	Belongs to the CinA family
HV240_RS11850	COG0366	Alpha amylase catalytic
HV240_RS11855	COG1294	oxidase, subunit
HV240_RS11860	COG1271	oxidase subunit
HV240_RS11865	COG3546	catalase activity
HV240_RS11870	COG3685	Protein conserved in bacteria
HV240_RS11875	COG3685	Protein conserved in bacteria
HV240_RS11880	COG3729	General stress protein
HV240_RS11905	COG0307	riboflavin synthase, alpha
HV240_RS11910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV240_RS11915	COG2814	Major facilitator Superfamily
HV240_RS11920	COG0583	DNA-binding transcription factor activity
HV240_RS11935	COG2814	Major facilitator Superfamily
HV240_RS11940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HV240_RS11945	COG0791	NLP P60 protein
HV240_RS11950	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HV240_RS11960	COG0346	lactoylglutathione lyase activity
HV240_RS11965	COG1902	pentaerythritol trinitrate reductase activity
HV240_RS11970	COG1309	transcriptional regulator
HV240_RS11975	COG3313	Fe-S protein
HV240_RS11980	COG4989	oxidoreductase activity
HV240_RS11990	COG1289	transmembrane transporter activity
HV240_RS11995	COG1566	PFAM secretion protein HlyD family protein
HV240_RS12010	COG3706	GGDEF domain
HV240_RS12025	COG3895	Periplasmic Protein
HV240_RS12045	COG0625	glutathione transferase activity
HV240_RS12055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HV240_RS12065	COG4659	FMN binding
HV240_RS12100	COG2723	6-phospho-beta-galactosidase activity
HV240_RS12110	COG0673	inositol 2-dehydrogenase activity
HV240_RS12125	COG0425	Belongs to the sulfur carrier protein TusA family
HV240_RS12130	COG2391	methyltransferase activity
HV240_RS12140	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV240_RS12145	COG1263	PTS System
HV240_RS12145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV240_RS12150	COG1609	Transcriptional regulator
HV240_RS12155	COG5339	Protein conserved in bacteria
HV240_RS12165	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV240_RS12165	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV240_RS12170	COG0114	fumarate hydratase activity
HV240_RS12180	COG2205	protein histidine kinase activity
HV240_RS12190	COG0745	RESPONSE REGULATOR receiver
HV240_RS12200	COG3136	membrane protein required for alginate biosynthesis
HV240_RS12210	COG0531	amino acid
HV240_RS12225	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HV240_RS12230	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HV240_RS12240	COG0589	response to stress
HV240_RS12245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV240_RS12255	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HV240_RS12260	COG1473	amidohydrolase
HV240_RS12270	COG0583	DNA-binding transcription factor activity
HV240_RS12275	COG2840	Smr protein MutS2
HV240_RS12280	COG1414	Transcriptional regulator
HV240_RS12290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HV240_RS12295	COG0183	Belongs to the thiolase family
HV240_RS12305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HV240_RS12310	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV240_RS12315	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV240_RS12315	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV240_RS12335	COG4565	transcriptional regulatory protein
HV240_RS12340	COG3290	protein histidine kinase activity
HV240_RS12350	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS12355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HV240_RS12370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HV240_RS12380	COG0679	Auxin Efflux Carrier
HV240_RS12410	COG0628	permease
HV240_RS12425	COG3300	MHYT domain
HV240_RS12425	COG5001	Diguanylate cyclase
HV240_RS12430	COG3591	Belongs to the peptidase S1B family
HV240_RS12445	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HV240_RS12450	COG2814	Major facilitator Superfamily
HV240_RS12455	COG0583	DNA-binding transcription factor activity
HV240_RS12460	COG1940	carbohydrate kinase activity
HV240_RS12465	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HV240_RS12480	COG3302	dmso reductase anchor subunit
HV240_RS12485	COG0437	4 iron, 4 sulfur cluster binding
HV240_RS12505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV240_RS12520	COG4948	Mandelate Racemase Muconate Lactonizing
HV240_RS12525	COG1063	alcohol dehydrogenase
HV240_RS12530	COG0582	viral genome integration into host DNA
HV240_RS12580	COG3723	Recombinational DNA repair protein, rece pathway
HV240_RS12705	COG3772	lysozyme
HV240_RS12740	COG0494	nUDIX hydrolase
HV240_RS12870	COG0246	Mannitol dehydrogenase
HV240_RS12880	COG0589	response to stress
HV240_RS12885	COG1802	Transcriptional regulator
HV240_RS12890	COG4221	oxidoreductase activity
HV240_RS12895	COG0339	signal peptide processing
HV240_RS12910	COG3122	Protein conserved in bacteria
HV240_RS12935	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HV240_RS12995	COG3210	domain, Protein
HV240_RS13025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HV240_RS13045	COG1129	ABC transporter
HV240_RS13060	COG2814	Major facilitator Superfamily
HV240_RS13065	COG0697	spore germination
HV240_RS13110	COG2731	YhcH YjgK YiaL family protein
HV240_RS13120	COG0861	Integral membrane protein TerC family
HV240_RS13125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV240_RS13130	COG1454	alcohol dehydrogenase
HV240_RS13135	COG3395	kinase activity
HV240_RS13140	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HV240_RS13145	COG1349	DNA-binding transcription factor activity
HV240_RS13150	COG0039	L-malate dehydrogenase activity
HV240_RS13160	COG0583	DNA-binding transcription factor activity
HV240_RS13165	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS13180	COG2199	diguanylate cyclase activity
HV240_RS13225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV240_RS13230	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV240_RS13255	COG2814	Major facilitator Superfamily
HV240_RS13280	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS13290	COG3039	Transposase
HV240_RS13330	COG0477	Major facilitator Superfamily
HV240_RS13345	COG2011	ABC-type metal ion transport system permease component
HV240_RS13365	COG4628	conserved protein (DUF2132)
HV240_RS13395	COG0765	amino acid transport
HV240_RS13410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV240_RS13415	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS13420	COG1070	Carbohydrate kinase
HV240_RS13450	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS13465	COG1609	Transcriptional regulator
HV240_RS13475	COG0693	protein deglycase activity
HV240_RS13490	COG0412	Dienelactone hydrolase
HV240_RS13495	COG0583	DNA-binding transcription factor activity
HV240_RS13520	COG2841	Protein conserved in bacteria
HV240_RS13545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS13560	COG4821	SIS domain
HV240_RS13565	COG2188	Transcriptional regulator
HV240_RS13605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HV240_RS13635	COG3539	Fimbrial protein
HV240_RS13640	COG3121	Chaperone
HV240_RS13645	COG3539	Fimbrial protein
HV240_RS13690	COG3391	amine dehydrogenase activity
HV240_RS13695	COG4771	TonB-dependent receptor
HV240_RS13705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV240_RS13720	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS13730	COG1609	Transcriptional regulator
HV240_RS13765	COG1652	LysM domain
HV240_RS13770	COG4771	TonB-dependent receptor
HV240_RS13775	COG1021	2,3-dihydroxybenzoate-AMP ligase
HV240_RS13800	COG2814	Major facilitator Superfamily
HV240_RS13805	COG1169	isochorismate synthase
HV240_RS13830	COG0814	amino acid
HV240_RS13835	COG1760	l-serine dehydratase
HV240_RS13845	COG3039	Transposase
HV240_RS13875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HV240_RS13880	COG0022	dehydrogenase e1 component
HV240_RS13885	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV240_RS13890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV240_RS13905	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HV240_RS13910	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS13920	COG0401	homolog of Blt101
HV240_RS13930	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV240_RS13935	COG2771	luxR family
HV240_RS13935	COG2200	EAL domain
HV240_RS13980	COG1609	Transcriptional regulator
HV240_RS13985	COG1082	Xylose isomerase domain protein TIM barrel
HV240_RS13990	COG0673	inositol 2-dehydrogenase activity
HV240_RS13995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HV240_RS14000	COG1116	anion transmembrane transporter activity
HV240_RS14005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV240_RS14010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV240_RS14015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV240_RS14020	COG0076	glutamate decarboxylase activity
HV240_RS14035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HV240_RS14035	COG0519	Catalyzes the synthesis of GMP from XMP
HV240_RS14050	COG0439	Biotin carboxylase
HV240_RS14065	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HV240_RS14090	COG1280	lysine exporter protein (LysE YggA)
HV240_RS14125	COG1285	pathogenesis
HV240_RS14135	COG2271	Major facilitator Superfamily
HV240_RS14145	COG0583	DNA-binding transcription factor activity
HV240_RS14150	COG0583	DNA-binding transcription factor activity
HV240_RS14165	COG0243	molybdopterin cofactor binding
HV240_RS14170	COG3781	membrane
HV240_RS14185	COG1764	response to oxidative stress
HV240_RS14195	COG0583	DNA-binding transcription factor activity
HV240_RS14215	COG0488	(ABC) transporter
HV240_RS14230	COG1064	alcohol dehydrogenase
HV240_RS14265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV240_RS14275	COG2814	Major facilitator Superfamily
HV240_RS14285	COG2864	formate dehydrogenase
HV240_RS14290	COG0437	4 iron, 4 sulfur cluster binding
HV240_RS14305	COG0697	spore germination
HV240_RS14320	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HV240_RS14330	COG3485	protocatechuate 3,4-dioxygenase
HV240_RS14335	COG4829	muconolactone delta-isomerase
HV240_RS14340	COG4948	Mandelate Racemase Muconate Lactonizing
HV240_RS14345	COG1414	Transcriptional regulator
HV240_RS14360	COG2223	nitrite transmembrane transporter activity
HV240_RS14365	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV240_RS14370	COG1140	nitrate reductase beta subunit
HV240_RS14375	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV240_RS14380	COG2181	nitrate reductase activity
HV240_RS14385	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HV240_RS14390	COG1178	ABC-type Fe3 transport system permease component
HV240_RS14400	COG3842	ATPase activity
HV240_RS14405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV240_RS14430	COG1126	abc transporter atp-binding protein
HV240_RS14450	COG1473	amidohydrolase
HV240_RS14455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV240_RS14480	COG4772	TonB-dependent receptor
HV240_RS14485	COG3691	Protein conserved in bacteria
HV240_RS14495	COG2130	NADP-dependent
HV240_RS14505	COG1247	-acetyltransferase
HV240_RS14510	COG3238	Protein conserved in bacteria
HV240_RS14520	COG0747	negative chemotaxis
HV240_RS14525	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS14530	COG4677	pectinesterase activity
HV240_RS14535	COG0596	Alpha beta hydrolase
HV240_RS14560	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS14565	COG1177	transmembrane transport
HV240_RS14570	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV240_RS14575	COG3842	ATPase activity
HV240_RS14580	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV240_RS14585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV240_RS14590	COG1271	oxidase subunit
HV240_RS14595	COG1294	oxidase, subunit
HV240_RS14610	COG0826	peptidase U32
HV240_RS14615	COG1396	sequence-specific DNA binding
HV240_RS14625	COG3135	benzoate transporter
HV240_RS14630	COG3708	Transcriptional regulator
HV240_RS14630	COG2207	Transcriptional regulator
HV240_RS14635	COG0697	spore germination
HV240_RS14645	COG0747	negative chemotaxis
HV240_RS14650	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV240_RS14655	COG0500	methyltransferase
HV240_RS14660	COG1275	C4-dicarboxylate transporter malic acid transport protein
HV240_RS14665	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV240_RS14670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV240_RS14680	COG1335	isochorismatase
HV240_RS14690	COG5383	Protein conserved in bacteria
HV240_RS14695	COG3485	protocatechuate 3,4-dioxygenase
HV240_RS14700	COG3485	protocatechuate 3,4-dioxygenase
HV240_RS14705	COG0583	DNA-binding transcription factor activity
HV240_RS14730	COG3038	cytochrome b561
HV240_RS14755	COG3706	GGDEF domain
HV240_RS14760	COG0583	DNA-binding transcription factor activity
HV240_RS14765	COG0456	acetyltransferase
HV240_RS14770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HV240_RS14775	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS14780	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV240_RS14785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HV240_RS14810	COG4122	O-methyltransferase activity
HV240_RS14815	COG1643	Atp-dependent helicase
HV240_RS14830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV240_RS14835	COG3327	negative regulation of DNA-templated transcription, initiation
HV240_RS14840	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HV240_RS14845	COG0183	Belongs to the thiolase family
HV240_RS14850	COG2050	protein possibly involved in aromatic compounds catabolism
HV240_RS14855	COG1250	3-hydroxyacyl-CoA dehydrogenase
HV240_RS14860	COG1024	Enoyl-CoA hydratase
HV240_RS14865	COG1024	Enoyl-CoA hydratase
HV240_RS14870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV240_RS14875	COG2151	metal-sulfur cluster biosynthetic enzyme
HV240_RS14880	COG3396	Phenylacetate-CoA oxygenase
HV240_RS14885	COG3460	Phenylacetate-CoA oxygenase
HV240_RS14890	COG3396	Phenylacetate-CoA oxygenase
HV240_RS14895	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS14895	COG2030	dehydratase
HV240_RS14910	COG3813	Protein conserved in bacteria
HV240_RS14915	COG0583	DNA-binding transcription factor activity
HV240_RS14930	COG1733	regulation of RNA biosynthetic process
HV240_RS15015	COG1126	abc transporter atp-binding protein
HV240_RS15020	COG5285	phytanoyl-CoA dioxygenase
HV240_RS15035	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS15040	COG2207	Transcriptional regulator
HV240_RS15045	COG3784	Protein of unknown function (DUF1318)
HV240_RS15055	COG2911	Protein conserved in bacteria
HV240_RS15065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HV240_RS15070	COG3187	Heat shock protein
HV240_RS15075	COG3042	response to heat
HV240_RS15120	COG0674	pyruvate-flavodoxin oxidoreductase activity
HV240_RS15120	COG1013	pyruvate-flavodoxin oxidoreductase activity
HV240_RS15120	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HV240_RS15120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV240_RS15125	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV240_RS15145	COG0513	Belongs to the DEAD box helicase family
HV240_RS15160	COG1349	DNA-binding transcription factor activity
HV240_RS15165	COG0673	inositol 2-dehydrogenase activity
HV240_RS15170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HV240_RS15195	COG3477	response to acidic pH
HV240_RS15200	COG2885	chlorophyll binding
HV240_RS15200	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HV240_RS15215	COG0583	DNA-binding transcription factor activity
HV240_RS15230	COG0583	DNA-binding transcription factor activity
HV240_RS15255	COG0789	Transcriptional regulator
HV240_RS15265	COG0300	oxidoreductase activity
HV240_RS15280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV240_RS15300	COG3272	Protein of unknown function (DUF1722)
HV240_RS15305	COG4580	involved in the transport of maltose and maltodextrins
HV240_RS15350	COG0740	serine-type endopeptidase activity
HV240_RS15425	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HV240_RS15435	COG1484	DNA-dependent DNA replication
HV240_RS15520	COG0582	viral genome integration into host DNA
HV240_RS15525	COG0693	protein deglycase activity
HV240_RS15530	COG4166	transmembrane transport
HV240_RS15535	COG2866	Carboxypeptidase
HV240_RS15540	COG4948	Mandelate Racemase Muconate Lactonizing
HV240_RS15545	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HV240_RS15550	COG3180	Ammonia monooxygenase
HV240_RS15565	COG3106	COG3106 Predicted ATPase
HV240_RS15570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV240_RS15580	COG1983	PspC domain protein
HV240_RS15590	COG1842	Phage shock protein A
HV240_RS15595	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV240_RS15605	COG1473	amidohydrolase
HV240_RS15620	COG4166	transmembrane transport
HV240_RS15630	COG4171	peptide transport system, permease
HV240_RS15640	COG4172	Belongs to the ABC transporter superfamily
HV240_RS15650	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HV240_RS15655	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV240_RS15655	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV240_RS15670	COG1349	DNA-binding transcription factor activity
HV240_RS15680	COG0023	Translation Initiation Factor
HV240_RS15690	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HV240_RS15695	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HV240_RS15700	COG0671	phosphoesterase, PA-phosphatase related
HV240_RS15710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HV240_RS15735	COG0616	signal peptide processing
HV240_RS15740	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS15745	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HV240_RS15755	COG1472	Belongs to the glycosyl hydrolase 3 family
HV240_RS15760	COG2211	Major facilitator Superfamily
HV240_RS15765	COG1187	pseudouridine synthase activity
HV240_RS15770	COG4907	membrane protein (DUF2207)
HV240_RS15775	COG0009	L-threonylcarbamoyladenylate synthase
HV240_RS15785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HV240_RS15790	COG0512	Glutamine amidotransferase of anthranilate synthase
HV240_RS15790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV240_RS15795	COG0134	indole-3-glycerol-phosphate synthase activity
HV240_RS15795	COG0135	phosphoribosylanthranilate isomerase activity
HV240_RS15815	COG1063	alcohol dehydrogenase
HV240_RS15895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV240_RS15905	COG0582	viral genome integration into host DNA
HV240_RS15910	COG3047	cAMP biosynthetic process
HV240_RS15940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV240_RS15945	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS15950	COG1988	membrane-bound metal-dependent
HV240_RS15965	COG0753	catalase activity
HV240_RS15975	COG1486	melibiose metabolic process
HV240_RS15980	COG2169	Transcriptional regulator
HV240_RS15980	COG1917	Cupin 2, conserved barrel domain protein
HV240_RS15985	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV240_RS15990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV240_RS15995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV240_RS16000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV240_RS16010	COG0322	excinuclease ABC activity
HV240_RS16015	COG4907	membrane protein (DUF2207)
HV240_RS16020	COG1704	LemA family
HV240_RS16025	COG3678	ATP-independent chaperone mediated protein folding
HV240_RS16045	COG3138	arginine N-succinyltransferase
HV240_RS16055	COG0708	Exodeoxyribonuclease III
HV240_RS16060	COG0398	Pfam SNARE associated Golgi protein
HV240_RS16065	COG0398	Pfam SNARE associated Golgi protein
HV240_RS16070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV240_RS16075	COG4134	Bacterial extracellular solute-binding protein
HV240_RS16080	COG4135	transport system, permease component
HV240_RS16085	COG4136	ATPase activity
HV240_RS16090	COG2897	thiosulfate sulfurtransferase activity
HV240_RS16095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HV240_RS16100	COG0494	nUDIX hydrolase
HV240_RS16110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HV240_RS16115	COG0709	Synthesizes selenophosphate from selenide and ATP
HV240_RS16125	COG0778	Nitroreductase
HV240_RS16130	COG0616	signal peptide processing
HV240_RS16135	COG0252	asparaginase activity
HV240_RS16140	COG1335	isochorismatase
HV240_RS16145	COG2814	Major facilitator Superfamily
HV240_RS16150	COG1349	DNA-binding transcription factor activity
HV240_RS16155	COG0667	Aldo Keto reductase
HV240_RS16160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV240_RS16165	COG0191	fructose-bisphosphate aldolase activity
HV240_RS16170	COG1063	alcohol dehydrogenase
HV240_RS16175	COG2271	Major facilitator Superfamily
HV240_RS16180	COG1063	alcohol dehydrogenase
HV240_RS16195	COG3139	Protein of unknown function (DUF1315)
HV240_RS16215	COG0656	L-ascorbic acid biosynthetic process
HV240_RS16220	COG3713	MltA-interacting MipA family protein
HV240_RS16225	COG2766	serine protein kinase
HV240_RS16345	COG1802	Transcriptional regulator
HV240_RS16345	COG4626	Terminase
HV240_RS16390	COG1403	HNH endonuclease
HV240_RS16400	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HV240_RS16410	COG1846	Transcriptional regulator
HV240_RS16495	COG0582	viral genome integration into host DNA
HV240_RS16500	COG0859	PFAM glycosyl transferase family 9
HV240_RS16520	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV240_RS16555	COG4974	Belongs to the 'phage' integrase family
HV240_RS16560	COG2199	diguanylate cyclase activity
HV240_RS16560	COG2203	Gaf domain
HV240_RS16580	COG3182	Iron-regulated membrane protein
HV240_RS16590	COG1560	Kdo2-lipid A biosynthetic process
HV240_RS16595	COG1595	DNA-templated transcription, initiation
HV240_RS16600	COG3712	iron ion homeostasis
HV240_RS16605	COG4772	TonB-dependent receptor
HV240_RS16610	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HV240_RS16615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV240_RS16620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV240_RS16625	COG1120	ATPase activity
HV240_RS16635	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HV240_RS16640	COG3706	GGDEF domain
HV240_RS16645	COG0583	DNA-binding transcription factor activity
HV240_RS16660	COG0538	isocitrate dehydrogenase activity
HV240_RS16685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HV240_RS16700	COG2814	Major facilitator Superfamily
HV240_RS16710	COG0745	RESPONSE REGULATOR receiver
HV240_RS16715	COG2205	protein histidine kinase activity
HV240_RS16720	COG2850	peptidyl-arginine hydroxylation
HV240_RS16740	COG1177	transmembrane transport
HV240_RS16755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HV240_RS16765	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV240_RS16770	COG1136	(ABC) transporter
HV240_RS16775	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV240_RS16780	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HV240_RS16785	COG1376	ErfK ybiS ycfS ynhG family protein
HV240_RS16785	COG1388	LysM domain
HV240_RS16800	COG1309	transcriptional regulator
HV240_RS16810	COG3134	Outer membrane lipoprotein
HV240_RS16815	COG1252	NADH dehydrogenase
HV240_RS16840	COG5633	Lipoprotein
HV240_RS16845	COG0537	adenosine 5'-monophosphoramidase activity
HV240_RS16850	COG4773	Receptor
HV240_RS16855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV240_RS16855	COG1263	PTS System
HV240_RS16860	COG0084	hydrolase, TatD family'
HV240_RS16865	COG0470	DNA polymerase III
HV240_RS16875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HV240_RS16880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV240_RS16885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV240_RS16900	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HV240_RS16920	COG1399	metal-binding, possibly nucleic acid-binding protein
HV240_RS16925	COG0424	maF-like protein
HV240_RS16940	COG1530	ribonuclease E activity
HV240_RS16945	COG0583	DNA-binding transcription factor activity
HV240_RS16950	COG2814	Major facilitator Superfamily
HV240_RS16960	COG0673	inositol 2-dehydrogenase activity
HV240_RS16970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV240_RS16980	COG2999	glutathione oxidoreductase activity
HV240_RS17020	COG1560	Kdo2-lipid A biosynthetic process
HV240_RS17035	COG5645	(Lipo)protein
HV240_RS17075	COG3381	protein complex oligomerization
HV240_RS17095	COG0583	DNA-binding transcription factor activity
HV240_RS17105	COG1335	isochorismatase
HV240_RS17125	COG5002	protein histidine kinase activity
HV240_RS17125	COG3850	Histidine kinase
HV240_RS17145	COG1702	phosphate starvation-inducible protein PhoH
HV240_RS17150	COG2837	iron assimilation
HV240_RS17155	COG2822	iron ion transport
HV240_RS17165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV240_RS17175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV240_RS17190	COG1309	transcriptional regulator
HV240_RS17225	COG2233	PERMEase
HV240_RS17230	COG3729	General stress protein
HV240_RS17260	COG0531	amino acid
HV240_RS17265	COG0174	glutamine synthetase
HV240_RS17270	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HV240_RS17275	COG1396	sequence-specific DNA binding
HV240_RS17275	COG1917	Cupin 2, conserved barrel domain protein
HV240_RS17280	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS17285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HV240_RS17290	COG0583	DNA-binding transcription factor activity
HV240_RS17295	COG0473	3-isopropylmalate dehydrogenase activity
HV240_RS17300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV240_RS17300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS17300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS17305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV240_RS17310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV240_RS17315	COG1882	Formate acetyltransferase
HV240_RS17320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV240_RS17325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV240_RS17335	COG2207	Transcriptional regulator
HV240_RS17340	COG3706	GGDEF domain
HV240_RS17360	COG0287	Prephenate dehydrogenase
HV240_RS17360	COG1605	Chorismate mutase
HV240_RS17370	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HV240_RS17385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HV240_RS17450	COG1953	Uracil, thiamine, allantoin
HV240_RS17455	COG0402	S-adenosylhomocysteine deaminase activity
HV240_RS17460	COG2351	hydroxyisourate hydrolase activity
HV240_RS17470	COG2233	PERMEase
HV240_RS17475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV240_RS17530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HV240_RS17540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV240_RS17550	COG1278	Cold shock
HV240_RS17555	COG1278	Cold shock
HV240_RS17575	COG1309	transcriptional regulator
HV240_RS17615	COG1486	melibiose metabolic process
HV240_RS17620	COG2223	nitrite transmembrane transporter activity
HV240_RS17640	COG0670	Belongs to the BI1 family
HV240_RS17655	COG2207	Transcriptional regulator
HV240_RS17660	COG1881	PFAM PEBP family protein
HV240_RS17680	COG0438	transferase activity, transferring glycosyl groups
HV240_RS17685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV240_RS17690	COG2274	protein secretion by the type I secretion system
HV240_RS17705	COG1832	CoA-binding protein
HV240_RS17715	COG0210	DNA helicase
HV240_RS17720	COG3304	Inner membrane component domain
HV240_RS17725	COG1289	transmembrane transporter activity
HV240_RS17730	COG3070	regulator of competence-specific genes
HV240_RS17755	COG1067	ATP-dependent peptidase activity
HV240_RS17765	COG3130	regulation of translation
HV240_RS17770	COG3009	Protein conserved in bacteria
HV240_RS17775	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV240_RS17775	COG3008	intermembrane lipid transfer
HV240_RS17780	COG2995	paraquat-inducible protein a
HV240_RS17785	COG0488	(ABC) transporter
HV240_RS17795	COG3217	Mosc domain protein beta barrel domain protein
HV240_RS17795	COG0633	Ferredoxin
HV240_RS17810	COG0431	NADPH-dependent FMN reductase
HV240_RS17815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV240_RS17825	COG0308	aminopeptidase N
HV240_RS17840	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV240_RS17845	COG1448	Aminotransferase
HV240_RS17850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV240_RS17855	COG3108	Peptidase M15
HV240_RS17860	COG2989	Protein conserved in bacteria
HV240_RS17870	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HV240_RS17880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HV240_RS17885	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV240_RS17890	COG3173	Aminoglycoside phosphotransferase
HV240_RS17905	COG3214	Protein conserved in bacteria
HV240_RS17915	COG1132	(ABC) transporter
HV240_RS17920	COG0658	competence protein
HV240_RS17920	COG2333	competence protein COMEC
HV240_RS17930	COG0539	negative regulation of cytoplasmic translation
HV240_RS17940	COG0501	Belongs to the peptidase M48B family
HV240_RS17955	COG2323	membrane
HV240_RS17960	COG1944	ATP diphosphatase activity
HV240_RS17965	COG2116	formate transmembrane transporter activity
HV240_RS17970	COG1882	Formate acetyltransferase
HV240_RS17975	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV240_RS17980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HV240_RS17995	COG3959	Transketolase, thiamine diphosphate binding domain
HV240_RS18000	COG3958	Transketolase
HV240_RS18005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS18010	COG0477	Major facilitator Superfamily
HV240_RS18015	COG3302	dmso reductase anchor subunit
HV240_RS18020	COG0437	4 iron, 4 sulfur cluster binding
HV240_RS18025	COG0243	molybdopterin cofactor binding
HV240_RS18035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HV240_RS18045	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV240_RS18045	COG1674	ftsk spoiiie
HV240_RS18055	COG0492	ferredoxin-NADP+ reductase activity
HV240_RS18060	COG4988	ABC transporter
HV240_RS18065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HV240_RS18075	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HV240_RS18080	COG0542	response to heat
HV240_RS18090	COG1278	Cold shock
HV240_RS18100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV240_RS18105	COG3593	DNA synthesis involved in DNA repair
HV240_RS18110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HV240_RS18115	COG2431	L-lysine efflux transmembrane transporter activity
HV240_RS18125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV240_RS18135	COG0028	Belongs to the TPP enzyme family
HV240_RS18140	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HV240_RS18145	COG0702	epimerase
HV240_RS18150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV240_RS18155	COG3023	N-Acetylmuramoyl-L-alanine amidase
HV240_RS18160	COG0393	Putative heavy-metal-binding
HV240_RS18170	COG1126	abc transporter atp-binding protein
HV240_RS18175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV240_RS18180	COG4215	(ABC) transporter
HV240_RS18185	COG4160	amino acid transport
HV240_RS18190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV240_RS18200	COG0745	RESPONSE REGULATOR receiver
HV240_RS18215	COG1177	transmembrane transport
HV240_RS18220	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV240_RS18225	COG3842	ATPase activity
HV240_RS18230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV240_RS18245	COG0778	Nitroreductase
HV240_RS18270	COG3226	Transcriptional regulator
HV240_RS18275	COG0738	Major facilitator superfamily
HV240_RS18280	COG0561	phosphatase activity
HV240_RS18285	COG2814	Major facilitator Superfamily
HV240_RS18290	COG0671	phosphoesterase, PA-phosphatase related
HV240_RS18295	COG1349	DNA-binding transcription factor activity
HV240_RS18300	COG1686	Belongs to the peptidase S11 family
HV240_RS18305	COG0625	glutathione transferase activity
HV240_RS18310	COG2133	pyrroloquinoline quinone binding
HV240_RS18320	COG2223	nitrite transmembrane transporter activity
HV240_RS18345	COG0747	negative chemotaxis
HV240_RS18355	COG1446	asparaginase
HV240_RS18360	COG0303	'Molybdopterin
HV240_RS18365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV240_RS18370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV240_RS18375	COG1882	Formate acetyltransferase
HV240_RS18380	COG0561	phosphatase activity
HV240_RS18390	COG1609	Transcriptional regulator
HV240_RS18395	COG2271	Major facilitator Superfamily
HV240_RS18405	COG0488	(ABC) transporter
HV240_RS18415	COG1376	ErfK ybiS ycfS ynhG family protein
HV240_RS18420	COG2188	Transcriptional regulator
HV240_RS18425	COG2723	6-phospho-beta-galactosidase activity
HV240_RS18430	COG0667	Aldo Keto reductase
HV240_RS18435	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV240_RS18450	COG2194	sulfuric ester hydrolase activity
HV240_RS18455	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HV240_RS18470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV240_RS18475	COG0765	amino acid transport
HV240_RS18480	COG1126	abc transporter atp-binding protein
HV240_RS18485	COG0668	transmembrane transport
HV240_RS18500	COG4774	siderophore transport
HV240_RS18510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV240_RS18520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV240_RS18530	COG0513	Belongs to the DEAD box helicase family
HV240_RS18535	COG3958	Transketolase
HV240_RS18540	COG3959	Transketolase, thiamine diphosphate binding domain
HV240_RS18545	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS18550	COG2271	Major facilitator Superfamily
HV240_RS18555	COG0583	DNA-binding transcription factor activity
HV240_RS18560	COG1309	transcriptional regulator
HV240_RS18570	COG1131	(ABC) transporter
HV240_RS18575	COG0842	Transport permease protein
HV240_RS18580	COG0842	Transport permease protein
HV240_RS18590	COG3568	Endonuclease Exonuclease Phosphatase
HV240_RS18595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV240_RS18600	COG0392	lysyltransferase activity
HV240_RS18605	COG0670	Belongs to the BI1 family
HV240_RS18610	COG0314	molybdopterin synthase activity
HV240_RS18615	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HV240_RS18625	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV240_RS18670	COG2226	methyltransferase
HV240_RS18685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HV240_RS18690	COG1881	PFAM PEBP family protein
HV240_RS18730	COG4677	pectinesterase activity
HV240_RS18745	COG0789	Transcriptional regulator
HV240_RS18750	COG2200	EAL domain
HV240_RS18770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV240_RS18785	COG0561	phosphatase activity
HV240_RS18795	COG4149	molybdate abc transporter
HV240_RS18800	COG0725	ABC transporter, periplasmic molybdate-binding protein
HV240_RS18810	COG3585	molybdate ion transport
HV240_RS18810	COG2005	Transcriptional regulator
HV240_RS18815	COG1119	ATPase activity
HV240_RS18825	COG1085	galactose-1-phosphate uridylyltransferase
HV240_RS18835	COG2017	converts alpha-aldose to the beta-anomer
HV240_RS18845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV240_RS18860	COG3201	nicotinamide mononucleotide transporter
HV240_RS18865	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HV240_RS18900	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HV240_RS18905	COG2885	chlorophyll binding
HV240_RS18915	COG3064	Membrane
HV240_RS18915	COG3064	Membrane
HV240_RS18920	COG0848	biopolymer transport protein
HV240_RS18925	COG0811	peptide transport
HV240_RS18930	COG0824	Thioesterase
HV240_RS18935	COG3790	cyd operon protein YbgE
HV240_RS18940	COG4890	Cyd operon protein YbgT
HV240_RS18945	COG1294	oxidase, subunit
HV240_RS18950	COG1271	oxidase subunit
HV240_RS18955	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV240_RS18965	COG4865	methylaspartate mutase activity
HV240_RS18970	COG3799	methylaspartate ammonia-lyase activity
HV240_RS18985	COG1301	dicarboxylic acid transport
HV240_RS18995	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV240_RS18995	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV240_RS19005	COG0583	DNA-binding transcription factor activity
HV240_RS19015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV240_RS19025	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV240_RS19030	COG0567	Dehydrogenase, E1 component
HV240_RS19035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV240_RS19040	COG1053	succinate dehydrogenase
HV240_RS19045	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HV240_RS19055	COG0372	Belongs to the citrate synthase family
HV240_RS19085	COG1984	allophanate hydrolase subunit 2
HV240_RS19090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HV240_RS19095	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HV240_RS19105	COG0415	Belongs to the DNA photolyase family
HV240_RS19135	COG2205	protein histidine kinase activity
HV240_RS19140	COG0745	RESPONSE REGULATOR receiver
HV240_RS19145	COG0235	Class ii aldolase
HV240_RS19150	COG3623	hexulose-6-phosphate isomerase
HV240_RS19155	COG1070	Carbohydrate kinase
HV240_RS19160	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS19165	COG1129	ABC transporter
HV240_RS19170	COG1879	ABC-type sugar transport system periplasmic component
HV240_RS19175	COG1063	alcohol dehydrogenase
HV240_RS19180	COG1349	DNA-binding transcription factor activity
HV240_RS19190	COG0033	Phosphoglucomutase
HV240_RS19200	COG0596	Alpha beta hydrolase
HV240_RS19215	COG0735	belongs to the Fur family
HV240_RS19220	COG0583	DNA-binding transcription factor activity
HV240_RS19225	COG1053	succinate dehydrogenase
HV240_RS19265	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV240_RS19270	COG1940	carbohydrate kinase activity
HV240_RS19270	COG1846	Transcriptional regulator
HV240_RS19275	COG0647	UMP catabolic process
HV240_RS19280	COG0367	asparagine synthase
HV240_RS19320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV240_RS19330	COG1702	phosphate starvation-inducible protein PhoH
HV240_RS19335	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HV240_RS19340	COG4535	Mg2 and Co2 transporter CorC
HV240_RS19355	COG0765	amino acid transport
HV240_RS19360	COG0765	amino acid transport
HV240_RS19365	COG1126	abc transporter atp-binding protein
HV240_RS19375	COG3210	domain, Protein
HV240_RS19380	COG2888	peptidyl-tyrosine sulfation
HV240_RS19395	COG1466	dna polymerase III delta subunit
HV240_RS19410	COG0799	negative regulation of ribosome biogenesis
HV240_RS19420	COG0768	penicillin binding
HV240_RS19425	COG0772	Belongs to the SEDS family
HV240_RS19430	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV240_RS19435	COG1686	Belongs to the peptidase S11 family
HV240_RS19450	COG0583	DNA-binding transcription factor activity
HV240_RS19460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HV240_RS19465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV240_RS19485	COG3069	C4-dicarboxylate transmembrane transporter activity
HV240_RS19490	COG3719	Belongs to the RNase T2 family
HV240_RS19495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV240_RS19505	COG3634	alkyl hydroperoxide reductase activity
HV240_RS19515	COG0583	DNA-binding transcription factor activity
HV240_RS19520	COG3969	phosphoadenosine phosphosulfate
HV240_RS19525	COG1475	DNA binding
HV240_RS19530	COG0436	Aminotransferase
HV240_RS19535	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
HV240_RS19540	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HV240_RS19560	COG1129	ABC transporter
HV240_RS19565	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS19570	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS19580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV240_RS19595	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HV240_RS19605	COG0402	S-adenosylhomocysteine deaminase activity
HV240_RS19615	COG0483	inositol monophosphate 1-phosphatase activity
HV240_RS19620	COG2271	Major facilitator Superfamily
HV240_RS19650	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS19655	COG1129	ABC transporter
HV240_RS19660	COG0371	Dehydrogenase
HV240_RS19675	COG2879	small protein
HV240_RS19680	COG1966	Carbon starvation protein
HV240_RS19690	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS19695	COG1535	isochorismatase
HV240_RS19695	COG3433	isochorismatase activity
HV240_RS19700	COG1021	2,3-dihydroxybenzoate-AMP ligase
HV240_RS19705	COG1169	isochorismate synthase
HV240_RS19710	COG4592	Periplasmic binding protein
HV240_RS19720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV240_RS19725	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV240_RS19730	COG1120	ATPase activity
HV240_RS19735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HV240_RS19735	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HV240_RS19740	COG3251	PFAM MbtH domain protein
HV240_RS19745	COG2382	esterase
HV240_RS19750	COG4771	TonB-dependent receptor
HV240_RS19755	COG2977	Belongs to the P-Pant transferase superfamily
HV240_RS19760	COG3958	Transketolase
HV240_RS19765	COG3959	Transketolase, thiamine diphosphate binding domain
HV240_RS19770	COG2390	Transcriptional regulator
HV240_RS19775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HV240_RS19780	COG1879	ABC-type sugar transport system periplasmic component
HV240_RS19790	COG1129	ABC transporter
HV240_RS19795	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS19805	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS19815	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HV240_RS19845	COG4221	oxidoreductase activity
HV240_RS19860	COG0765	amino acid transport
HV240_RS19865	COG0765	amino acid transport
HV240_RS19880	COG1280	lysine exporter protein (LysE YggA)
HV240_RS19890	COG0697	spore germination
HV240_RS19905	COG0444	Belongs to the ABC transporter superfamily
HV240_RS19910	COG4608	Belongs to the ABC transporter superfamily
HV240_RS19915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV240_RS19925	COG4166	transmembrane transport
HV240_RS19935	COG3698	Phosphodiester glycosidase
HV240_RS19965	COG4774	siderophore transport
HV240_RS19985	COG2315	Protein conserved in bacteria
HV240_RS19990	COG0778	Nitroreductase
HV240_RS20000	COG0477	Major facilitator Superfamily
HV240_RS20005	COG0668	transmembrane transport
HV240_RS20015	COG0494	nUDIX hydrolase
HV240_RS20035	COG3188	usher protein
HV240_RS20050	COG2771	luxR family
HV240_RS20055	COG0583	DNA-binding transcription factor activity
HV240_RS20060	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS20075	COG1082	Xylose isomerase domain protein TIM barrel
HV240_RS20080	COG2211	Major facilitator Superfamily
HV240_RS20085	COG1113	amino acid transport
HV240_RS20095	COG0667	Aldo Keto reductase
HV240_RS20100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV240_RS20105	COG1473	amidohydrolase
HV240_RS20145	COG3550	peptidyl-serine autophosphorylation
HV240_RS20155	COG3711	transcriptional antiterminator
HV240_RS20160	COG2723	6-phospho-beta-galactosidase activity
HV240_RS20165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV240_RS20165	COG1263	PTS System
HV240_RS20165	COG2190	(PTS) system
HV240_RS20170	COG0583	DNA-binding transcription factor activity
HV240_RS20210	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS20215	COG1129	ABC transporter
HV240_RS20230	COG0673	inositol 2-dehydrogenase activity
HV240_RS20240	COG2367	Beta-lactamase
HV240_RS20255	COG3104	oligopeptide transport
HV240_RS20260	COG1982	Orn Lys Arg decarboxylase major
HV240_RS20265	COG0531	amino acid
HV240_RS20270	COG3710	Transcriptional regulator
HV240_RS20280	COG0583	DNA-binding transcription factor activity
HV240_RS20290	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HV240_RS20310	COG1285	pathogenesis
HV240_RS20315	COG2211	Major facilitator Superfamily
HV240_RS20430	COG0582	viral genome integration into host DNA
HV240_RS20445	COG2501	S4 domain
HV240_RS20455	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HV240_RS20470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HV240_RS20475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HV240_RS20480	COG0549	Belongs to the carbamate kinase family
HV240_RS20490	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV240_RS20495	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV240_RS20500	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV240_RS20505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV240_RS20510	COG3257	ureidoglycine aminohydrolase activity
HV240_RS20515	COG1929	Belongs to the glycerate kinase type-1 family
HV240_RS20520	COG2233	PERMEase
HV240_RS20530	COG1953	Uracil, thiamine, allantoin
HV240_RS20540	COG2084	Dehydrogenase
HV240_RS20545	COG3622	Belongs to the hyi family
HV240_RS20550	COG3960	tartronate-semialdehyde synthase activity
HV240_RS20585	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HV240_RS20590	COG4181	ATPase activity
HV240_RS20595	COG2755	lipolytic protein G-D-S-L family
HV240_RS20600	COG0300	oxidoreductase activity
HV240_RS20605	COG3118	belongs to the thioredoxin family
HV240_RS20610	COG0390	transport system, permease component
HV240_RS20615	COG4619	ABC transporter
HV240_RS20620	COG0330	HflC and HflK could
HV240_RS20625	COG1585	Membrane protein implicated in regulation of membrane protease activity
HV240_RS20645	COG0811	peptide transport
HV240_RS20665	COG3735	TraB family
HV240_RS20670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV240_RS20680	COG2223	nitrite transmembrane transporter activity
HV240_RS20685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HV240_RS20685	COG4651	solute:proton antiporter activity
HV240_RS20690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV240_RS20720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HV240_RS20730	COG2832	Protein of unknown function (DUF454)
HV240_RS20735	COG3923	Primosomal replication protein n
HV240_RS20750	COG3264	Mechanosensitive ion channel
HV240_RS20750	COG1196	nuclear chromosome segregation
HV240_RS20755	COG1309	transcriptional regulator
HV240_RS20760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV240_RS20765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV240_RS20780	COG0110	maltose O-acetyltransferase activity
HV240_RS20800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HV240_RS20820	COG1263	PTS System
HV240_RS20820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV240_RS20825	COG1874	Beta-galactosidase
HV240_RS20830	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HV240_RS20835	COG3833	ABC-type maltose transport systems, permease component
HV240_RS20840	COG1175	transmembrane transport
HV240_RS20845	COG2182	Extracellular solute-binding protein
HV240_RS20855	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV240_RS20870	COG5507	3-demethylubiquinone-9 3-methyltransferase
HV240_RS20875	COG2364	Membrane
HV240_RS20905	COG3695	enzyme binding
HV240_RS20910	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HV240_RS20915	COG1946	Acyl-CoA thioesterase
HV240_RS20920	COG0583	DNA-binding transcription factor activity
HV240_RS20925	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV240_RS20930	COG1811	Na channel or pump
HV240_RS20935	COG0004	ammonium transporteR
HV240_RS20940	COG0347	Belongs to the P(II) protein family
HV240_RS20945	COG1132	(ABC) transporter
HV240_RS20950	COG1132	(ABC) transporter
HV240_RS20955	COG1522	sequence-specific DNA binding
HV240_RS20970	COG4533	DNA binding
HV240_RS20980	COG0824	Thioesterase
HV240_RS20985	COG1555	photosystem II stabilization
HV240_RS20990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV240_RS20995	COG0776	regulation of translation
HV240_RS21000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HV240_RS21020	COG0271	Belongs to the BolA IbaG family
HV240_RS21025	COG3056	Lipoprotein
HV240_RS21030	COG2223	nitrite transmembrane transporter activity
HV240_RS21035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HV240_RS21040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HV240_RS21045	COG1845	cytochrome c oxidase, subunit III
HV240_RS21050	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HV240_RS21065	COG1414	Transcriptional regulator
HV240_RS21100	COG2211	Major facilitator Superfamily
HV240_RS21105	COG0673	inositol 2-dehydrogenase activity
HV240_RS21110	COG2814	Major facilitator Superfamily
HV240_RS21120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HV240_RS21140	COG0142	geranyltranstransferase activity
HV240_RS21150	COG0667	Aldo Keto reductase
HV240_RS21155	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HV240_RS21160	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HV240_RS21175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV240_RS21175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV240_RS21185	COG4238	major outer membrane lipoprotein
HV240_RS21210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV240_RS21215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV240_RS21220	COG1862	Preprotein translocase
HV240_RS21235	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HV240_RS21240	COG0450	alkyl hydroperoxide reductase
HV240_RS21255	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HV240_RS21265	COG1335	isochorismatase
HV240_RS21270	COG0583	DNA-binding transcription factor activity
HV240_RS21275	COG0366	Alpha amylase catalytic
HV240_RS21300	COG0420	3'-5' exonuclease activity
HV240_RS21305	COG0419	ATPase involved in DNA repair
HV240_RS21315	COG1940	carbohydrate kinase activity
HV240_RS21330	COG4126	flavin adenine dinucleotide binding
HV240_RS21340	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HV240_RS21345	COG3416	Protein conserved in bacteria
HV240_RS21355	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HV240_RS21365	COG1785	Belongs to the alkaline phosphatase family
HV240_RS21375	COG1609	Transcriptional regulator
HV240_RS21385	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS21420	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HV240_RS21430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HV240_RS21435	COG0113	porphobilinogen synthase activity
HV240_RS21450	COG2175	clavaminate synthase activity
HV240_RS21455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV240_RS21460	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HV240_RS21465	COG4521	taurine ABC transporter
HV240_RS21480	COG2271	Major facilitator Superfamily
HV240_RS21485	COG1840	ABC-type Fe3 transport system, periplasmic component
HV240_RS21495	COG3842	ATPase activity
HV240_RS21500	COG2040	homocysteine
HV240_RS21505	COG0833	amino acid
HV240_RS21510	COG5434	Belongs to the glycosyl hydrolase 28 family
HV240_RS21515	COG0531	amino acid
HV240_RS21520	COG4303	Ethanolamine ammonia lyase large subunit
HV240_RS21525	COG4302	ethanolamine ammonia-lyase activity
HV240_RS21565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV240_RS21570	COG1126	abc transporter atp-binding protein
HV240_RS21575	COG0765	amino acid transport
HV240_RS21580	COG0765	amino acid transport
HV240_RS21595	COG3188	usher protein
HV240_RS21620	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HV240_RS21630	COG3639	organic phosphonate transmembrane transporter activity
HV240_RS21650	COG3118	belongs to the thioredoxin family
HV240_RS21660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV240_RS21670	COG0583	DNA-binding transcription factor activity
HV240_RS21675	COG0791	NLP P60 protein
HV240_RS21680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV240_RS21685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HV240_RS21690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HV240_RS21715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV240_RS21725	COG1733	regulation of RNA biosynthetic process
HV240_RS21730	COG2085	NADP oxidoreductase coenzyme F420-dependent
HV240_RS21735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV240_RS21750	COG1309	transcriptional regulator
HV240_RS21760	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV240_RS21770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV240_RS21780	COG0477	Major facilitator Superfamily
HV240_RS21790	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HV240_RS21795	COG3153	acetyltransferase
HV240_RS21810	COG0246	Mannitol dehydrogenase
HV240_RS21815	COG2186	Transcriptional regulator
HV240_RS21835	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS21840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HV240_RS21850	COG1596	polysaccharide export
HV240_RS21870	COG0463	Glycosyl transferase, family 2
HV240_RS21875	COG0438	transferase activity, transferring glycosyl groups
HV240_RS21880	COG0438	transferase activity, transferring glycosyl groups
HV240_RS21880	COG0297	glycogen (starch) synthase activity
HV240_RS21895	COG1045	serine acetyltransferase
HV240_RS21915	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV240_RS21920	COG0454	-acetyltransferase
HV240_RS21935	COG2991	Protein conserved in bacteria
HV240_RS21950	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV240_RS21955	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV240_RS21970	COG3034	peptidoglycan biosynthetic process
HV240_RS21975	COG0121	glutamine amidotransferase
HV240_RS21985	COG1960	acyl-CoA dehydrogenase activity
HV240_RS21990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV240_RS22010	COG2226	methyltransferase
HV240_RS22020	COG0741	lytic transglycosylase activity
HV240_RS22020	COG1388	LysM domain
HV240_RS22025	COG2226	methyltransferase
HV240_RS22035	COG2814	Major facilitator Superfamily
HV240_RS22040	COG0583	DNA-binding transcription factor activity
HV240_RS22045	COG0656	L-ascorbic acid biosynthetic process
HV240_RS22080	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HV240_RS22090	COG2011	ABC-type metal ion transport system permease component
HV240_RS22095	COG1464	Belongs to the NlpA lipoprotein family
HV240_RS22105	COG1720	tRNA m6t6A37 methyltransferase activity
HV240_RS22115	COG3015	lipoprotein NlpE involved in copper resistance
HV240_RS22120	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HV240_RS22125	COG4681	YaeQ
HV240_RS22135	COG4568	rho-dependent transcription termination
HV240_RS22145	COG0346	lactoylglutathione lyase activity
HV240_RS22180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HV240_RS22185	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HV240_RS22190	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HV240_RS22200	COG0750	zinc metalloprotease
HV240_RS22205	COG0575	Belongs to the CDS family
HV240_RS22215	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HV240_RS22230	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HV240_RS22240	COG0024	Methionine aminopeptidase
HV240_RS22245	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HV240_RS22260	COG3835	regulator
HV240_RS22265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV240_RS22285	COG2860	membrane
HV240_RS22305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV240_RS22310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV240_RS22315	COG1120	ATPase activity
HV240_RS22320	COG4774	siderophore transport
HV240_RS22325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HV240_RS22410	COG1643	Atp-dependent helicase
HV240_RS22415	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HV240_RS22435	COG0617	tRNA 3'-terminal CCA addition
HV240_RS22440	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HV240_RS22455	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HV240_RS22460	COG0726	polysaccharide deacetylase
HV240_RS22465	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS22470	COG0842	Transport permease protein
HV240_RS22475	COG1131	(ABC) transporter
HV240_RS22480	COG0288	reversible hydration of carbon dioxide
HV240_RS22500	COG1802	Transcriptional regulator
HV240_RS22500	COG4626	Terminase
HV240_RS22555	COG3039	Transposase
HV240_RS22565	COG4993	Dehydrogenase
HV240_RS22570	COG2132	Multicopper oxidase
HV240_RS22585	COG0545	Peptidyl-prolyl cis-trans isomerase
HV240_RS22610	COG3064	Membrane
HV240_RS22625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV240_RS22630	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV240_RS22635	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HV240_RS22640	COG2186	Transcriptional regulator
HV240_RS22645	COG1113	amino acid transport
HV240_RS22650	COG2211	Major facilitator Superfamily
HV240_RS22655	COG3940	Belongs to the glycosyl hydrolase 43 family
HV240_RS22660	COG3725	Membrane protein required for beta-lactamase induction
HV240_RS22675	COG4969	Belongs to the N-Me-Phe pilin family
HV240_RS22680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV240_RS22685	COG1459	type II secretion system
HV240_RS22710	COG0494	nUDIX hydrolase
HV240_RS22730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HV240_RS22735	COG0849	cell division
HV240_RS22760	COG0772	Belongs to the SEDS family
HV240_RS22775	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HV240_RS22785	COG0768	penicillin binding
HV240_RS22805	COG1609	Transcriptional regulator
HV240_RS22815	COG0028	Belongs to the TPP enzyme family
HV240_RS22835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HV240_RS22860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV240_RS22865	COG0738	Major facilitator superfamily
HV240_RS22875	COG0583	DNA-binding transcription factor activity
HV240_RS22885	COG2814	Major facilitator Superfamily
HV240_RS22905	COG1178	ABC-type Fe3 transport system permease component
HV240_RS22915	COG0586	Pfam SNARE associated Golgi protein
HV240_RS22935	COG0235	Class ii aldolase
HV240_RS22940	COG0417	DNA replication proofreading
HV240_RS22950	COG0564	pseudouridine synthase activity
HV240_RS22960	COG3493	citrate carrier protein
HV240_RS22975	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HV240_RS23035	COG1940	carbohydrate kinase activity
HV240_RS23115	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HV240_RS23130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HV240_RS23135	COG0471	metal ion transport
HV240_RS23140	COG0471	metal ion transport
HV240_RS23145	COG2828	Protein conserved in bacteria
HV240_RS23150	COG0583	DNA-binding transcription factor activity
HV240_RS23165	COG1047	Peptidyl-prolyl cis-trans
HV240_RS23180	COG0196	riboflavin kinase activity
HV240_RS23190	COG0583	DNA-binding transcription factor activity
HV240_RS23225	COG4735	regulation of single-species biofilm formation
HV240_RS23230	COG1584	GPR1 FUN34 yaaH family protein
HV240_RS23240	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV240_RS23245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HV240_RS23250	COG1115	amino acid carrier protein
HV240_RS23260	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HV240_RS23270	COG0460	homoserine dehydrogenase
HV240_RS23270	COG0527	aspartate kinase activity
HV240_RS23280	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HV240_RS23290	COG0745	RESPONSE REGULATOR receiver
HV240_RS23295	COG4452	Inner membrane protein CreD
HV240_RS23300	COG2205	protein histidine kinase activity
HV240_RS23305	COG0745	RESPONSE REGULATOR receiver
HV240_RS23310	COG3045	CreA protein
HV240_RS23315	COG3708	Transcriptional regulator
HV240_RS23315	COG2207	Transcriptional regulator
HV240_RS23335	COG0741	lytic transglycosylase activity
HV240_RS23340	COG0488	(ABC) transporter
HV240_RS23350	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HV240_RS23355	COG0560	Phosphoserine phosphatase
HV240_RS23360	COG3726	membrane protein affecting hemolysin expression
HV240_RS23370	COG0813	purine-nucleoside phosphorylase activity
HV240_RS23390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV240_RS23395	COG0084	hydrolase, TatD family'
HV240_RS23400	COG4667	esterase of the alpha-beta hydrolase superfamily
HV240_RS23405	COG5487	UPF0391 membrane protein
HV240_RS23410	COG2823	Periplasmic or secreted lipoprotein
HV240_RS23420	COG1011	Hydrolase
HV240_RS23425	COG0456	acetyltransferase
HV240_RS23430	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HV240_RS23460	COG3706	GGDEF domain
HV240_RS23465	COG4114	ferric iron reductase
HV240_RS23470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV240_RS23475	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV240_RS23480	COG2197	response regulator
HV240_RS23485	COG2197	response regulator
HV240_RS23490	COG2207	Transcriptional regulator
HV240_RS23500	COG2966	Psort location CytoplasmicMembrane, score
HV240_RS23515	COG1484	DNA-dependent DNA replication
HV240_RS23530	COG5464	transposase or invertase
HV240_RS23540	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HV240_RS23545	COG3716	PTS system mannose fructose sorbose family IID component
HV240_RS23550	COG3715	PTS system
HV240_RS23565	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV240_RS23565	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HV240_RS23575	COG1063	alcohol dehydrogenase
HV240_RS23580	COG1802	Transcriptional regulator
HV240_RS23585	COG2271	Major facilitator Superfamily
HV240_RS23590	COG0456	acetyltransferase
HV240_RS23600	COG1737	Transcriptional regulator
HV240_RS23605	COG0800	Aldolase
HV240_RS23610	COG3734	2-keto-3-deoxy-galactonokinase
HV240_RS23615	COG4145	pantothenate transmembrane transporter activity
HV240_RS23625	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HV240_RS23635	COG1846	Transcriptional regulator
HV240_RS23640	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV240_RS23650	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS23655	COG3384	dioxygenase
HV240_RS23665	COG3971	2-oxopent-4-enoate hydratase activity
HV240_RS23685	COG2368	4-hydroxyphenylacetate
HV240_RS23690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV240_RS23695	COG1966	Carbon starvation protein
HV240_RS23700	COG2879	small protein
HV240_RS23705	COG0523	cobalamin synthesis protein
HV240_RS23720	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS23755	COG2733	membrane
HV240_RS23760	COG2814	Major facilitator Superfamily
HV240_RS23765	COG1475	DNA binding
HV240_RS23770	COG3969	phosphoadenosine phosphosulfate
HV240_RS23780	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HV240_RS23785	COG1924	4 iron, 4 sulfur cluster binding
HV240_RS23795	COG1473	amidohydrolase
HV240_RS23800	COG0700	Nucleoside recognition
HV240_RS23805	COG3366	ferrous iron transmembrane transporter activity
HV240_RS23810	COG0583	DNA-binding transcription factor activity
HV240_RS23820	COG1566	PFAM secretion protein HlyD family protein
HV240_RS23830	COG5457	Domain of unknown function (DUF1127)
HV240_RS23835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV240_RS23840	COG1715	Restriction endonuclease
HV240_RS23845	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HV240_RS23850	COG0732	type I restriction modification DNA specificity domain
HV240_RS23855	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HV240_RS23880	COG0531	amino acid
HV240_RS23895	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV240_RS23930	COG1454	alcohol dehydrogenase
HV240_RS23930	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS23940	COG1454	alcohol dehydrogenase
HV240_RS23940	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS23945	COG1882	Formate acetyltransferase
HV240_RS23950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV240_RS23960	COG4869	propanediol catabolic process
HV240_RS23990	COG0814	amino acid
HV240_RS24000	COG3706	GGDEF domain
HV240_RS24005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV240_RS24010	COG1129	ABC transporter
HV240_RS24010	COG0842	Transport permease protein
HV240_RS24015	COG0842	Transport permease protein
HV240_RS24045	COG2850	peptidyl-arginine hydroxylation
HV240_RS24050	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HV240_RS24055	COG0588	phosphoglycerate mutase activity
HV240_RS24065	COG0477	Major facilitator Superfamily
HV240_RS24075	COG0477	Major facilitator Superfamily
HV240_RS24080	COG4948	Mandelate Racemase Muconate Lactonizing
HV240_RS24085	COG1028	Short-chain dehydrogenase reductase Sdr
HV240_RS24090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV240_RS24140	COG1215	transferase activity, transferring glycosyl groups
HV240_RS24160	COG2003	Belongs to the UPF0758 family
HV240_RS24225	COG1061	Type III restriction enzyme res subunit
HV240_RS24250	COG0582	viral genome integration into host DNA
HV240_RS24260	COG1064	alcohol dehydrogenase
HV240_RS24265	COG1175	transmembrane transport
HV240_RS24270	COG0395	ABC-type sugar transport system, permease component
HV240_RS24275	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HV240_RS24280	COG3842	ATPase activity
HV240_RS24290	COG2814	Major facilitator Superfamily
HV240_RS24300	COG1082	Xylose isomerase domain protein TIM barrel
HV240_RS24310	COG3962	Belongs to the TPP enzyme family
HV240_RS24315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV240_RS24320	COG1737	Transcriptional regulator
HV240_RS24320	COG0837	glucose binding
HV240_RS24325	COG3718	enzyme involved in inositol metabolism
HV240_RS24340	COG0433	COG0433 Predicted ATPase
HV240_RS24345	COG0795	lipopolysaccharide-transporting ATPase activity
HV240_RS24350	COG0795	lipopolysaccharide-transporting ATPase activity
HV240_RS24360	COG2927	DNA polymerase III (CHI subunit)
HV240_RS24365	COG0525	valine-tRNA ligase activity
HV240_RS24390	COG2731	YhcH YjgK YiaL family protein
HV240_RS24415	COG0251	oxidation-reduction process
HV240_RS24430	COG1263	PTS System
HV240_RS24430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV240_RS24435	COG0366	Alpha amylase catalytic
HV240_RS24440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV240_RS24445	COG1486	melibiose metabolic process
HV240_RS24465	COG0602	queuosine metabolic process
HV240_RS24470	COG3501	Rhs element vgr protein
HV240_RS24485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV240_RS24485	COG3711	transcriptional antiterminator
HV240_RS24490	COG2706	6-phosphogluconolactonase activity
HV240_RS24505	COG3964	amidohydrolase
HV240_RS24540	COG0312	modulator of DNA gyrase
HV240_RS24550	COG1012	belongs to the aldehyde dehydrogenase family
HV240_RS24570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HV240_RS24580	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS24585	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS24590	COG1129	ABC transporter
HV240_RS24595	COG1879	ABC-type sugar transport system periplasmic component
HV240_RS24605	COG2105	PFAM AIG2 family protein
HV240_RS24610	COG2911	Protein conserved in bacteria
HV240_RS24615	COG0729	surface antigen
HV240_RS24625	COG1253	flavin adenine dinucleotide binding
HV240_RS24650	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HV240_RS24665	COG1733	regulation of RNA biosynthetic process
HV240_RS24670	COG0702	epimerase
HV240_RS24680	COG0697	spore germination
HV240_RS24690	COG1113	amino acid transport
HV240_RS24695	COG0545	Peptidyl-prolyl cis-trans isomerase
HV240_RS24700	COG3061	Opacity-associated protein A
HV240_RS24710	COG0359	binds to the 23S rRNA
HV240_RS24715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HV240_RS24720	COG2965	DNA replication, synthesis of RNA primer
HV240_RS24780	COG1073	alpha beta
HV240_RS24785	COG3650	response to hydrogen peroxide
HV240_RS24795	COG1960	acyl-CoA dehydrogenase activity
HV240_RS24805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV240_RS24810	COG0557	exoribonuclease II activity
HV240_RS24825	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HV240_RS24835	COG0330	HflC and HflK could
HV240_RS24840	COG0330	HflC and HflK could
HV240_RS24845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HV240_RS24865	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV240_RS24870	COG0802	atpase or kinase
HV240_RS24875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HV240_RS24875	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HV240_RS24880	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HV240_RS24900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV240_RS24905	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HV240_RS24920	COG1511	domain protein
HV240_RS24920	COG3264	Mechanosensitive ion channel
HV240_RS24930	COG1053	succinate dehydrogenase
HV240_RS24935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV240_RS24950	COG3040	lipid binding
HV240_RS24955	COG2076	Multidrug Resistance protein
HV240_RS25035	COG0459	protein refolding
HV240_RS25045	COG0531	amino acid
HV240_RS25050	COG3030	protein affecting phage T7 exclusion by the F plasmid
HV240_RS25055	COG1027	Aspartate ammonia-lyase
HV240_RS25060	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV240_RS25075	COG1309	transcriptional regulator
HV240_RS25090	COG0463	Glycosyl transferase, family 2
HV240_RS25105	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV240_RS25120	COG0861	Integral membrane protein TerC family
HV240_RS25140	COG2824	Alkylphosphonate utilization operon protein PhnA
HV240_RS25145	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HV240_RS25150	COG2188	Transcriptional regulator
HV240_RS25155	COG3624	Phosphonate C-P lyase system protein PhnG
HV240_RS25160	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HV240_RS25165	COG3626	phosphonate metabolism
HV240_RS25170	COG3627	carbon phosphorus lyase activity
HV240_RS25175	COG4107	phosphonate C-P lyase system protein PhnK
HV240_RS25180	COG4778	phosphonate C-P lyase system protein PhnL
HV240_RS25185	COG3454	Phosphonate metabolism
HV240_RS25190	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HV240_RS25195	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HV240_RS25205	COG0698	ribose 5-phosphate isomerase
HV240_RS25210	COG1737	Transcriptional regulator
HV240_RS25215	COG1879	ABC-type sugar transport system periplasmic component
HV240_RS25220	COG1129	ABC transporter
HV240_RS25225	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS25230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV240_RS25235	COG1940	carbohydrate kinase activity
HV240_RS25240	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HV240_RS25250	COG1566	PFAM secretion protein HlyD family protein
HV240_RS25255	COG1289	transmembrane transporter activity
HV240_RS25270	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HV240_RS25275	COG1301	dicarboxylic acid transport
HV240_RS25280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HV240_RS25285	COG3162	membrane
HV240_RS25290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV240_RS25325	COG1380	Effector of murein hydrolase LrgA
HV240_RS25330	COG0583	DNA-binding transcription factor activity
HV240_RS25345	COG0679	Auxin Efflux Carrier
HV240_RS25355	COG0025	NhaP-type Na H and K H
HV240_RS25360	COG2252	PERMEase
HV240_RS25385	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV240_RS25400	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV240_RS25410	COG4771	TonB-dependent receptor
HV240_RS25425	COG0629	single-stranded DNA binding
HV240_RS25430	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HV240_RS25445	COG2315	Protein conserved in bacteria
HV240_RS25450	COG0432	Pfam Uncharacterised protein family UPF0047
HV240_RS25460	COG1448	Aminotransferase
HV240_RS25465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HV240_RS25470	COG0305	Participates in initiation and elongation during chromosome replication
HV240_RS25485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV240_RS25495	COG0735	belongs to the Fur family
HV240_RS25500	COG3237	CsbD-like
HV240_RS25505	COG0534	Mate efflux family protein
HV240_RS25515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HV240_RS25540	COG4580	involved in the transport of maltose and maltodextrins
HV240_RS25575	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HV240_RS25585	COG0527	aspartate kinase activity
HV240_RS25590	COG3541	Predicted nucleotidyltransferase
HV240_RS25605	COG4650	regulator
HV240_RS25620	COG1187	pseudouridine synthase activity
HV240_RS25660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV240_RS25715	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HV240_RS25755	COG0151	Belongs to the GarS family
HV240_RS25765	COG4191	Histidine kinase
HV240_RS25805	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HV240_RS25820	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV240_RS25825	COG2104	thiamine diphosphate biosynthetic process
HV240_RS25840	COG3706	GGDEF domain
HV240_RS25850	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV240_RS25855	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV240_RS25890	COG0250	Participates in transcription elongation, termination and antitermination
HV240_RS25895	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HV240_RS25935	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HV240_RS25965	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HV240_RS25975	COG1739	Uncharacterized protein family UPF0029
HV240_RS26020	COG0805	protein transport
HV240_RS26025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HV240_RS26040	COG3165	ubiquinone biosynthetic process from chorismate
HV240_RS26060	COG0412	Dienelactone hydrolase
HV240_RS26075	COG0583	DNA-binding transcription factor activity
HV240_RS26080	COG0697	spore germination
HV240_RS26085	COG0561	phosphatase activity
HV240_RS26090	COG2267	carboxylic ester hydrolase activity
HV240_RS26095	COG1280	lysine exporter protein (LysE YggA)
HV240_RS26105	COG1280	lysine exporter protein (LysE YggA)
HV240_RS26120	COG2050	protein possibly involved in aromatic compounds catabolism
HV240_RS26130	COG0598	Magnesium transport protein CorA
HV240_RS26135	COG0210	DNA helicase
HV240_RS26140	COG1011	Hydrolase
HV240_RS26160	COG5567	small periplasmic lipoprotein
HV240_RS26170	COG3072	Adenylate cyclase
HV240_RS26180	COG1587	Uroporphyrinogen-III synthase
HV240_RS26185	COG2959	enzyme of heme biosynthesis
HV240_RS26190	COG3071	HemY protein
HV240_RS26235	COG2244	polysaccharide biosynthetic process
HV240_RS26240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HV240_RS26245	COG0456	acetyltransferase
HV240_RS26250	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HV240_RS26255	COG1088	dTDP-glucose 4,6-dehydratase activity
HV240_RS26260	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HV240_RS26265	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HV240_RS26275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HV240_RS26280	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HV240_RS26285	COG3118	belongs to the thioredoxin family
HV240_RS26300	COG0583	DNA-binding transcription factor activity
HV240_RS26310	COG1811	Na channel or pump
HV240_RS26320	COG1397	ADP-ribosylglycohydrolase
HV240_RS26330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV240_RS26345	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HV240_RS26355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV240_RS26360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV240_RS26370	COG0583	DNA-binding transcription factor activity
HV240_RS26375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV240_RS26385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV240_RS26390	COG3978	acetolactate synthase activity
HV240_RS26410	COG3085	chromosome segregation
HV240_RS26485	COG0583	DNA-binding transcription factor activity
HV240_RS26500	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HV240_RS26515	COG3443	Belongs to the bacterial solute-binding protein 9 family
HV240_RS26520	COG2207	Transcriptional regulator
HV240_RS26530	COG0371	Dehydrogenase
HV240_RS26535	COG1349	DNA-binding transcription factor activity
HV240_RS26545	COG0583	DNA-binding transcription factor activity
HV240_RS26550	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV240_RS26555	COG0527	aspartate kinase activity
HV240_RS26555	COG0460	homoserine dehydrogenase
HV240_RS26560	COG0626	cystathionine gamma-synthase activity
HV240_RS26575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HV240_RS26580	COG1609	Transcriptional regulator
HV240_RS26585	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV240_RS26600	COG1575	Belongs to the MenA family. Type 1 subfamily
HV240_RS26755	COG4695	Portal protein
HV240_RS26800	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV240_RS26850	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HV240_RS26855	COG3678	ATP-independent chaperone mediated protein folding
HV240_RS26860	COG0745	RESPONSE REGULATOR receiver
HV240_RS26865	COG2205	protein histidine kinase activity
HV240_RS26870	COG2258	MOSC domain
HV240_RS26915	COG1129	ABC transporter
HV240_RS26930	COG1454	alcohol dehydrogenase
HV240_RS26970	COG3715	PTS system
HV240_RS26975	COG3716	PTS system mannose fructose sorbose family IID component
HV240_RS27005	COG0437	4 iron, 4 sulfur cluster binding
HV240_RS27010	COG2864	formate dehydrogenase
HV240_RS27025	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV240_RS27035	COG0456	acetyltransferase
HV240_RS27040	COG1490	D-aminoacyl-tRNA deacylase activity
HV240_RS27050	COG1011	Hydrolase
HV240_RS27065	COG3852	Histidine kinase
HV240_RS27080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV240_RS27100	COG0204	Acyl-transferase
HV240_RS27110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HV240_RS27115	COG3084	Protein conserved in bacteria
HV240_RS27125	COG1763	Mo-molybdopterin cofactor biosynthetic process
HV240_RS27145	COG2186	Transcriptional regulator
HV240_RS27150	COG0477	Major facilitator Superfamily
HV240_RS27155	COG1609	Transcriptional regulator
HV240_RS27160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV240_RS27170	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV240_RS27175	COG1129	ABC transporter
HV240_RS27205	COG1522	sequence-specific DNA binding
HV240_RS27210	COG0716	FMN binding
HV240_RS27225	COG3312	ion transport
HV240_RS27285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HV240_RS27290	COG0573	inorganic phosphate transmembrane transporter activity
HV240_RS27295	COG0581	inorganic phosphate transmembrane transporter activity
HV240_RS27300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HV240_RS27305	COG0704	Plays a role in the regulation of phosphate uptake
HV240_RS27320	COG2382	esterase
HV240_RS27325	COG0363	glucosamine-6-phosphate deaminase activity
HV240_RS27330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV240_RS27335	COG2252	PERMEase
HV240_RS27340	COG0431	NADPH-dependent FMN reductase
HV240_RS27345	COG2091	lysine biosynthetic process via aminoadipic acid
HV240_RS27360	COG2731	YhcH YjgK YiaL family protein
HV240_RS27380	COG1737	Transcriptional regulator
HV240_RS27385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV240_RS27390	COG0456	acetyltransferase
HV240_RS27405	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HV240_RS27415	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HV240_RS27425	COG1192	Involved in chromosome partitioning
HV240_RS27550	COG4644	lycopene metabolic process
HV240_RS27585	COG0789	Transcriptional regulator
HV240_RS27685	COG2801	Transposase and inactivated derivatives
HV240_RS27730	COG4644	lycopene metabolic process
HV240_RS27775	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HV240_RS27780	COG3012	SEC-C Motif Domain Protein
HV240_RS27780	COG3318	Belongs to the UPF0149 family
HV240_RS27805	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HV240_RS28020	COG0789	Transcriptional regulator
HV240_RS28095	COG1475	DNA binding
HV240_RS28230	COG2223	nitrite transmembrane transporter activity
HV240_RS28240	COG1609	Transcriptional regulator
HV240_RS28260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV240_RS28315	COG0542	response to heat
HV240_RS28320	COG0071	Belongs to the small heat shock protein (HSP20) family
HV240_RS28425	COG0789	Transcriptional regulator
HV240_RS28465	COG2801	Transposase and inactivated derivatives
HV240_RS28550	COG3039	Transposase
HV240_RS28560	COG2205	protein histidine kinase activity
HV240_RS28565	COG0745	RESPONSE REGULATOR receiver
HV240_RS28570	COG1276	copper resistance
HV240_RS28575	COG2372	response to copper ion
HV240_RS28580	COG3667	copper resistance
HV240_RS28585	COG2132	Multicopper oxidase
HV240_RS28595	COG0739	heme binding
HV240_RS28625	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV240_RS28875	COG3039	Transposase
HV240_RS28970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HV240_RS29045	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV240_RS29190	COG3941	tape measure
HV240_RS29280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HV240_RS29285	COG1475	DNA binding
HV240_RS29290	COG1475	DNA binding
HV240_RS29385	COG0328	RNA-DNA hybrid ribonuclease activity
HV240_RS29410	COG3039	Transposase
HV240_RS29415	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HV240_RS29420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV240_RS29455	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV240_RS29460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV240_RS29515	COG3706	GGDEF domain