locus-tag	class	description
J415_RS00005	COG2850	peptidyl-arginine hydroxylation
J415_RS00010	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J415_RS00025	COG0477	Major facilitator Superfamily
J415_RS00035	COG0477	Major facilitator Superfamily
J415_RS00040	COG4948	Mandelate Racemase Muconate Lactonizing
J415_RS00045	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS00050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J415_RS00090	COG1715	Restriction endonuclease
J415_RS00105	COG2003	Belongs to the UPF0758 family
J415_RS00130	COG2378	regulation of single-species biofilm formation
J415_RS00150	COG3596	GTP binding
J415_RS00155	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J415_RS00170	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J415_RS00230	COG3153	acetyltransferase
J415_RS00235	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J415_RS00290	COG0582	viral genome integration into host DNA
J415_RS00310	COG1064	alcohol dehydrogenase
J415_RS00315	COG1175	transmembrane transport
J415_RS00320	COG0395	ABC-type sugar transport system, permease component
J415_RS00325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J415_RS00330	COG3842	ATPase activity
J415_RS00340	COG2814	Major facilitator Superfamily
J415_RS00350	COG1082	Xylose isomerase domain protein TIM barrel
J415_RS00360	COG3962	Belongs to the TPP enzyme family
J415_RS00365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J415_RS00370	COG0837	glucose binding
J415_RS00370	COG1737	Transcriptional regulator
J415_RS00375	COG3718	enzyme involved in inositol metabolism
J415_RS00390	COG0433	COG0433 Predicted ATPase
J415_RS00395	COG0795	lipopolysaccharide-transporting ATPase activity
J415_RS00400	COG0795	lipopolysaccharide-transporting ATPase activity
J415_RS00410	COG2927	DNA polymerase III (CHI subunit)
J415_RS00415	COG0525	valine-tRNA ligase activity
J415_RS00440	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J415_RS00445	COG2731	YhcH YjgK YiaL family protein
J415_RS00460	COG3397	chitin binding
J415_RS00465	COG0251	oxidation-reduction process
J415_RS00480	COG1263	PTS System
J415_RS00480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS00485	COG0366	Alpha amylase catalytic
J415_RS00490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J415_RS00495	COG1486	melibiose metabolic process
J415_RS00515	COG0602	queuosine metabolic process
J415_RS00535	COG3711	transcriptional antiterminator
J415_RS00535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS00540	COG2706	6-phosphogluconolactonase activity
J415_RS00555	COG3964	amidohydrolase
J415_RS00590	COG0312	modulator of DNA gyrase
J415_RS00600	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS00620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J415_RS00635	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS00640	COG1129	ABC transporter
J415_RS00645	COG1879	ABC-type sugar transport system periplasmic component
J415_RS00655	COG2105	PFAM AIG2 family protein
J415_RS00660	COG2911	Protein conserved in bacteria
J415_RS00665	COG0729	surface antigen
J415_RS00675	COG1253	flavin adenine dinucleotide binding
J415_RS00700	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J415_RS00715	COG1733	regulation of RNA biosynthetic process
J415_RS00720	COG0702	epimerase
J415_RS00730	COG0697	spore germination
J415_RS00740	COG1113	amino acid transport
J415_RS00745	COG0545	Peptidyl-prolyl cis-trans isomerase
J415_RS00750	COG3061	Opacity-associated protein A
J415_RS00760	COG0359	binds to the 23S rRNA
J415_RS00765	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J415_RS00770	COG2965	DNA replication, synthesis of RNA primer
J415_RS00830	COG1073	alpha beta
J415_RS00835	COG3650	response to hydrogen peroxide
J415_RS00845	COG1960	acyl-CoA dehydrogenase activity
J415_RS00855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J415_RS00860	COG0557	exoribonuclease II activity
J415_RS00875	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J415_RS00880	COG0330	HflC and HflK could
J415_RS00885	COG0330	HflC and HflK could
J415_RS00890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J415_RS00910	COG0860	N-Acetylmuramoyl-L-alanine amidase
J415_RS00915	COG0802	atpase or kinase
J415_RS00920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J415_RS00920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J415_RS00925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J415_RS00945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS00950	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J415_RS00965	COG3264	Mechanosensitive ion channel
J415_RS00965	COG1511	domain protein
J415_RS00980	COG1053	succinate dehydrogenase
J415_RS00985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J415_RS01000	COG3040	lipid binding
J415_RS01005	COG2076	Multidrug Resistance protein
J415_RS01025	COG1509	lysine 2,3-aminomutase activity
J415_RS01040	COG3121	Chaperone
J415_RS01080	COG0459	protein refolding
J415_RS01090	COG0531	amino acid
J415_RS01095	COG3030	protein affecting phage T7 exclusion by the F plasmid
J415_RS01100	COG1027	Aspartate ammonia-lyase
J415_RS01105	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J415_RS01120	COG1309	transcriptional regulator
J415_RS01135	COG2249	NAD(P)H dehydrogenase (quinone) activity
J415_RS01150	COG0861	Integral membrane protein TerC family
J415_RS01170	COG2824	Alkylphosphonate utilization operon protein PhnA
J415_RS01175	COG2764	glyoxalase bleomycin resistance protein dioxygenase
J415_RS01180	COG2188	Transcriptional regulator
J415_RS01185	COG3624	Phosphonate C-P lyase system protein PhnG
J415_RS01190	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
J415_RS01195	COG3626	phosphonate metabolism
J415_RS01200	COG3627	carbon phosphorus lyase activity
J415_RS01205	COG4107	phosphonate C-P lyase system protein PhnK
J415_RS01210	COG4778	phosphonate C-P lyase system protein PhnL
J415_RS01215	COG3454	Phosphonate metabolism
J415_RS01220	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
J415_RS01225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J415_RS01235	COG0698	ribose 5-phosphate isomerase
J415_RS01240	COG1737	Transcriptional regulator
J415_RS01245	COG1879	ABC-type sugar transport system periplasmic component
J415_RS01250	COG1129	ABC transporter
J415_RS01255	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS01260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J415_RS01265	COG1940	carbohydrate kinase activity
J415_RS01270	COG3383	formate dehydrogenase (NAD+) activity
J415_RS01275	COG3383	formate dehydrogenase (NAD+) activity
J415_RS01280	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J415_RS01285	COG1301	dicarboxylic acid transport
J415_RS01290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J415_RS01295	COG3162	membrane
J415_RS01325	COG3121	Chaperone
J415_RS01335	COG1346	cytolysis
J415_RS01340	COG1380	Effector of murein hydrolase LrgA
J415_RS01345	COG0583	DNA-binding transcription factor activity
J415_RS01355	COG2252	PERMEase
J415_RS01375	COG4943	cyclic-guanylate-specific phosphodiesterase activity
J415_RS01385	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J415_RS01395	COG4771	TonB-dependent receptor
J415_RS01400	COG0741	lytic transglycosylase activity
J415_RS01405	COG0629	single-stranded DNA binding
J415_RS01410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J415_RS01425	COG2315	Protein conserved in bacteria
J415_RS01430	COG0432	Pfam Uncharacterised protein family UPF0047
J415_RS01440	COG1448	Aminotransferase
J415_RS01445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J415_RS01450	COG0305	Participates in initiation and elongation during chromosome replication
J415_RS01465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J415_RS01475	COG0735	belongs to the Fur family
J415_RS01480	COG3237	CsbD-like
J415_RS01485	COG0534	Mate efflux family protein
J415_RS01495	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J415_RS01565	COG0251	oxidation-reduction process
J415_RS01575	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J415_RS01590	COG0527	aspartate kinase activity
J415_RS01595	COG3541	Predicted nucleotidyltransferase
J415_RS01605	COG4650	regulator
J415_RS01620	COG1187	pseudouridine synthase activity
J415_RS01660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J415_RS01710	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J415_RS01755	COG0151	Belongs to the GarS family
J415_RS01765	COG4191	Histidine kinase
J415_RS01805	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
J415_RS01820	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J415_RS01825	COG2104	thiamine diphosphate biosynthetic process
J415_RS01835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J415_RS01840	COG3706	GGDEF domain
J415_RS01850	COG1447	Phosphotransferase system cellobiose-specific component IIA
J415_RS01855	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J415_RS01890	COG0250	Participates in transcription elongation, termination and antitermination
J415_RS01895	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J415_RS01935	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J415_RS01965	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
J415_RS01975	COG1739	Uncharacterized protein family UPF0029
J415_RS02020	COG0805	protein transport
J415_RS02030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J415_RS02040	COG3165	ubiquinone biosynthetic process from chorismate
J415_RS02060	COG0412	Dienelactone hydrolase
J415_RS02080	COG0583	DNA-binding transcription factor activity
J415_RS02085	COG0697	spore germination
J415_RS02090	COG0561	phosphatase activity
J415_RS02095	COG2267	carboxylic ester hydrolase activity
J415_RS02100	COG1280	lysine exporter protein (LysE YggA)
J415_RS02110	COG1280	lysine exporter protein (LysE YggA)
J415_RS02125	COG2050	protein possibly involved in aromatic compounds catabolism
J415_RS02135	COG0598	Magnesium transport protein CorA
J415_RS02140	COG0210	DNA helicase
J415_RS02145	COG1011	Hydrolase
J415_RS02165	COG5567	small periplasmic lipoprotein
J415_RS02175	COG1228	amidohydrolase
J415_RS02180	COG0477	Major facilitator Superfamily
J415_RS02195	COG3072	Adenylate cyclase
J415_RS02205	COG1587	Uroporphyrinogen-III synthase
J415_RS02210	COG2959	enzyme of heme biosynthesis
J415_RS02215	COG3071	HemY protein
J415_RS02260	COG2244	polysaccharide biosynthetic process
J415_RS02265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J415_RS02270	COG0456	acetyltransferase
J415_RS02275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J415_RS02280	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J415_RS02290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J415_RS02295	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J415_RS02300	COG3118	belongs to the thioredoxin family
J415_RS02320	COG1397	ADP-ribosylglycohydrolase
J415_RS02355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J415_RS02360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J415_RS02370	COG0583	DNA-binding transcription factor activity
J415_RS02375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J415_RS02385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J415_RS02390	COG3978	acetolactate synthase activity
J415_RS02405	COG3085	chromosome segregation
J415_RS02480	COG0583	DNA-binding transcription factor activity
J415_RS02500	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J415_RS02515	COG3443	Belongs to the bacterial solute-binding protein 9 family
J415_RS02520	COG2207	Transcriptional regulator
J415_RS02530	COG0371	Dehydrogenase
J415_RS02535	COG1349	DNA-binding transcription factor activity
J415_RS02545	COG0583	DNA-binding transcription factor activity
J415_RS02550	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J415_RS02555	COG0460	homoserine dehydrogenase
J415_RS02555	COG0527	aspartate kinase activity
J415_RS02560	COG0626	cystathionine gamma-synthase activity
J415_RS02575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J415_RS02580	COG1609	Transcriptional regulator
J415_RS02585	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J415_RS02600	COG1575	Belongs to the MenA family. Type 1 subfamily
J415_RS02620	COG3678	ATP-independent chaperone mediated protein folding
J415_RS02625	COG0745	RESPONSE REGULATOR receiver
J415_RS02630	COG2205	protein histidine kinase activity
J415_RS02635	COG2258	MOSC domain
J415_RS02680	COG1129	ABC transporter
J415_RS02685	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS02695	COG1454	alcohol dehydrogenase
J415_RS02715	COG1621	beta-fructofuranosidase activity
J415_RS02720	COG2211	Major facilitator Superfamily
J415_RS02725	COG1609	Transcriptional regulator
J415_RS02740	COG0668	transmembrane transport
J415_RS02755	COG3121	Chaperone
J415_RS02765	COG3539	Fimbrial protein
J415_RS02780	COG3188	usher protein
J415_RS02785	COG3121	Chaperone
J415_RS02795	COG3539	Fimbrial protein
J415_RS02805	COG0110	maltose O-acetyltransferase activity
J415_RS02810	COG2211	Major facilitator Superfamily
J415_RS02855	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J415_RS02895	COG0205	6-phosphofructokinase activity
J415_RS02910	COG3383	formate dehydrogenase (NAD+) activity
J415_RS02910	COG0243	molybdopterin cofactor binding
J415_RS02915	COG3383	formate dehydrogenase (NAD+) activity
J415_RS02915	COG0243	molybdopterin cofactor binding
J415_RS02920	COG0437	4 iron, 4 sulfur cluster binding
J415_RS02925	COG2864	formate dehydrogenase
J415_RS02935	COG0657	acetylesterase activity
J415_RS02940	COG0456	acetyltransferase
J415_RS02945	COG1490	D-aminoacyl-tRNA deacylase activity
J415_RS02955	COG1011	Hydrolase
J415_RS02970	COG3852	Histidine kinase
J415_RS02980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J415_RS03000	COG0204	Acyl-transferase
J415_RS03010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J415_RS03015	COG3084	Protein conserved in bacteria
J415_RS03025	COG1763	Mo-molybdopterin cofactor biosynthetic process
J415_RS03060	COG0477	Major facilitator Superfamily
J415_RS03065	COG1609	Transcriptional regulator
J415_RS03070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J415_RS03080	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS03085	COG1129	ABC transporter
J415_RS03115	COG1522	sequence-specific DNA binding
J415_RS03120	COG0716	FMN binding
J415_RS03135	COG3312	ion transport
J415_RS03190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J415_RS03195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J415_RS03200	COG0573	inorganic phosphate transmembrane transporter activity
J415_RS03205	COG0581	inorganic phosphate transmembrane transporter activity
J415_RS03210	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J415_RS03215	COG0704	Plays a role in the regulation of phosphate uptake
J415_RS03225	COG2382	esterase
J415_RS03230	COG0363	glucosamine-6-phosphate deaminase activity
J415_RS03235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J415_RS03240	COG2252	PERMEase
J415_RS03245	COG0431	NADPH-dependent FMN reductase
J415_RS03250	COG2091	lysine biosynthetic process via aminoadipic acid
J415_RS03265	COG0456	acetyltransferase
J415_RS03290	COG0592	DNA-directed DNA polymerase activity
J415_RS03300	COG0187	DNA topoisomerase II activity
J415_RS03305	COG0583	DNA-binding transcription factor activity
J415_RS03315	COG0561	phosphatase activity
J415_RS03320	COG2186	Transcriptional regulator
J415_RS03325	COG3734	2-keto-3-deoxy-galactonokinase
J415_RS03330	COG0800	Aldolase
J415_RS03340	COG2271	Major facilitator Superfamily
J415_RS03345	COG0823	Involved in the tonB-independent uptake of proteins
J415_RS03350	COG5645	(Lipo)protein
J415_RS03370	COG2188	Transcriptional regulator
J415_RS03385	COG2149	membrane
J415_RS03395	COG0641	radical SAM
J415_RS03405	COG2610	gluconate transmembrane transporter activity
J415_RS03410	COG0583	DNA-binding transcription factor activity
J415_RS03415	COG2814	Major facilitator Superfamily
J415_RS03430	COG0028	Belongs to the TPP enzyme family
J415_RS03435	COG0440	acetolactate synthase activity
J415_RS03440	COG2197	response regulator
J415_RS03490	COG2188	Transcriptional regulator
J415_RS03520	COG1447	Phosphotransferase system cellobiose-specific component IIA
J415_RS03525	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J415_RS03525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J415_RS03535	COG1609	Transcriptional regulator
J415_RS03545	COG5464	transposase or invertase
J415_RS03555	COG0697	spore germination
J415_RS03570	COG1263	PTS System
J415_RS03570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS03580	COG2814	Major facilitator Superfamily
J415_RS03595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J415_RS03615	COG0583	DNA-binding transcription factor activity
J415_RS03630	COG1464	Belongs to the NlpA lipoprotein family
J415_RS03645	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
J415_RS03655	COG1064	alcohol dehydrogenase
J415_RS03675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J415_RS03705	COG2211	Major facilitator Superfamily
J415_RS03710	COG1501	Belongs to the glycosyl hydrolase 31 family
J415_RS03715	COG3711	transcriptional antiterminator
J415_RS03720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS03720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS03720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS03725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS03730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS03730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS03740	COG0191	fructose-bisphosphate aldolase activity
J415_RS03745	COG1940	carbohydrate kinase activity
J415_RS03760	COG1486	melibiose metabolic process
J415_RS03765	COG1263	PTS System
J415_RS03765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS03770	COG2982	Protein involved in outer membrane biogenesis
J415_RS03775	COG2233	PERMEase
J415_RS03780	COG0786	glutamate:sodium symporter activity
J415_RS03795	COG3074	FtsZ-dependent cytokinesis
J415_RS03825	COG3152	Membrane
J415_RS03835	COG1494	fructose-1,6-bisphosphatase
J415_RS03840	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J415_RS03845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J415_RS03850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J415_RS03870	COG2860	membrane
J415_RS03880	COG1561	YicC-like family, N-terminal region
J415_RS03890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J415_RS03905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J415_RS03915	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J415_RS03920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J415_RS03940	COG1519	Transferase
J415_RS03945	COG1216	Glycosyl transferase, family 2
J415_RS03950	COG0438	transferase activity, transferring glycosyl groups
J415_RS03960	COG0859	PFAM glycosyl transferase family 9
J415_RS03985	COG0859	PFAM glycosyl transferase family 9
J415_RS03990	COG0859	PFAM glycosyl transferase family 9
J415_RS04000	COG0156	8-amino-7-oxononanoate synthase activity
J415_RS04010	COG0463	Glycosyl transferase, family 2
J415_RS04015	COG2861	carbohydrate metabolic process
J415_RS04020	COG4942	peptidase
J415_RS04030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J415_RS04035	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J415_RS04055	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J415_RS04065	COG2186	Transcriptional regulator
J415_RS04085	COG3722	fumarate hydratase activity
J415_RS04105	COG1566	PFAM secretion protein HlyD family protein
J415_RS04110	COG0625	glutathione transferase activity
J415_RS04120	COG3276	selenocysteine insertion sequence binding
J415_RS04130	COG2211	Major facilitator Superfamily
J415_RS04135	COG4977	sequence-specific DNA binding
J415_RS04135	COG1917	Cupin 2, conserved barrel domain protein
J415_RS04140	COG0235	Class ii aldolase
J415_RS04145	COG3623	hexulose-6-phosphate isomerase
J415_RS04150	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
J415_RS04155	COG1070	Carbohydrate kinase
J415_RS04170	COG2731	YhcH YjgK YiaL family protein
J415_RS04180	COG1414	Transcriptional regulator
J415_RS04185	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J415_RS04190	COG3977	Valine--pyruvate aminotransferase
J415_RS04195	COG0366	Alpha amylase catalytic
J415_RS04200	COG2992	FlgJ-related protein
J415_RS04205	COG2207	Transcriptional regulator
J415_RS04205	COG1609	Transcriptional regulator
J415_RS04210	COG4214	carbohydrate transport
J415_RS04220	COG4213	ABC transporter substrate-binding protein
J415_RS04225	COG2115	Belongs to the xylose isomerase family
J415_RS04230	COG1070	Carbohydrate kinase
J415_RS04235	COG4682	membrane
J415_RS04240	COG3274	enterobacterial common antigen metabolic process
J415_RS04270	COG1278	Cold shock
J415_RS04275	COG2944	sequence-specific DNA binding
J415_RS04280	COG2814	Major facilitator Superfamily
J415_RS04300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J415_RS04310	COG1609	Transcriptional regulator
J415_RS04315	COG2885	chlorophyll binding
J415_RS04320	COG0243	molybdopterin cofactor binding
J415_RS04325	COG0456	acetyltransferase
J415_RS04330	COG2818	Glycosylase
J415_RS04335	COG5571	outer membrane autotransporter
J415_RS04340	COG2223	nitrite transmembrane transporter activity
J415_RS04355	COG0747	negative chemotaxis
J415_RS04360	COG0601	transmembrane transport
J415_RS04365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J415_RS04370	COG0444	Belongs to the ABC transporter superfamily
J415_RS04375	COG4608	Belongs to the ABC transporter superfamily
J415_RS04385	COG0489	protein tyrosine kinase activity
J415_RS04400	COG0457	Tetratricopeptide repeat
J415_RS04460	COG1215	transferase activity, transferring glycosyl groups
J415_RS04465	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
J415_RS04470	COG0457	Tetratricopeptide repeat
J415_RS04470	COG3118	belongs to the thioredoxin family
J415_RS04475	COG2200	EAL domain
J415_RS04475	COG2199	diguanylate cyclase activity
J415_RS04485	COG0612	Peptidase, M16
J415_RS04495	COG2982	Protein involved in outer membrane biogenesis
J415_RS04500	COG0477	Major facilitator Superfamily
J415_RS04505	COG1295	ribonuclease BN
J415_RS04510	COG0583	DNA-binding transcription factor activity
J415_RS04515	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS04520	COG2197	response regulator
J415_RS04540	COG1454	alcohol dehydrogenase
J415_RS04545	COG0625	glutathione transferase activity
J415_RS04550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J415_RS04555	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J415_RS04560	COG0671	phosphoesterase, PA-phosphatase related
J415_RS04575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J415_RS04580	COG2183	response to ionizing radiation
J415_RS04585	COG1918	ferrous iron import across plasma membrane
J415_RS04620	COG2610	gluconate transmembrane transporter activity
J415_RS04640	COG0589	response to stress
J415_RS04650	COG0306	phosphate transporter
J415_RS04655	COG2081	HI0933 family
J415_RS04660	COG2204	response regulator
J415_RS04665	COG3964	amidohydrolase
J415_RS04670	COG0471	metal ion transport
J415_RS04675	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J415_RS04680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J415_RS04690	COG2239	Acts as a magnesium transporter
J415_RS04710	COG0444	Belongs to the ABC transporter superfamily
J415_RS04715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J415_RS04720	COG0601	transmembrane transport
J415_RS04725	COG0747	negative chemotaxis
J415_RS04740	COG3479	Phenolic acid decarboxylase
J415_RS04780	COG2091	lysine biosynthetic process via aminoadipic acid
J415_RS04785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J415_RS04790	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS04800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J415_RS04825	COG1216	Glycosyl transferase, family 2
J415_RS04845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J415_RS04875	COG0628	permease
J415_RS04880	COG0477	Major facilitator Superfamily
J415_RS04890	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J415_RS04905	COG3714	YhhN family
J415_RS04915	COG3776	membrane
J415_RS04920	COG0742	ribosomal rna small subunit methyltransferase
J415_RS04925	COG0552	protein localization to endoplasmic reticulum
J415_RS04930	COG2884	Cell division ATP-binding protein ftsE
J415_RS04935	COG2177	Part of the ABC transporter FtsEX involved in
J415_RS04950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J415_RS04960	COG0683	leucine binding
J415_RS04970	COG0683	leucine binding
J415_RS04995	COG2721	sulfolactate sulfo-lyase activity
J415_RS05000	COG2271	Major facilitator Superfamily
J415_RS05005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J415_RS05010	COG1414	Transcriptional regulator
J415_RS05035	COG0584	glycerophosphoryl diester phosphodiesterase
J415_RS05045	COG0405	Gamma-glutamyltransferase
J415_RS05050	COG1247	-acetyltransferase
J415_RS05060	COG0673	inositol 2-dehydrogenase activity
J415_RS05065	COG1741	Belongs to the pirin family
J415_RS05070	COG1609	Transcriptional regulator
J415_RS05075	COG3265	gluconokinase activity
J415_RS05080	COG2610	gluconate transmembrane transporter activity
J415_RS05085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J415_RS05110	COG0058	SHG alpha-glucan phosphorylase activity
J415_RS05115	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J415_RS05130	COG1349	DNA-binding transcription factor activity
J415_RS05140	COG0058	SHG alpha-glucan phosphorylase activity
J415_RS05145	COG1640	4-alpha-glucanotransferase
J415_RS05160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J415_RS05165	COG1011	Hydrolase
J415_RS05175	COG0494	nUDIX hydrolase
J415_RS05180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J415_RS05200	COG4796	Type ii and iii secretion system protein
J415_RS05215	COG3266	domain, Protein
J415_RS05220	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J415_RS05225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J415_RS05250	COG2146	nitrite reductase [NAD(P)H] activity
J415_RS05255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J415_RS05260	COG0402	S-adenosylhomocysteine deaminase activity
J415_RS05265	COG0738	Major facilitator superfamily
J415_RS05285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J415_RS05290	COG1289	transmembrane transporter activity
J415_RS05300	COG1765	OsmC-like protein
J415_RS05305	COG3954	Phosphoribulokinase
J415_RS05315	COG0429	hydrolase of the alpha beta-hydrolase fold
J415_RS05325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J415_RS05335	COG0488	(ABC) transporter
J415_RS05350	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
J415_RS05355	COG1047	Peptidyl-prolyl cis-trans
J415_RS05365	COG0545	Peptidyl-prolyl cis-trans isomerase
J415_RS05370	COG2964	Protein conserved in bacteria
J415_RS05425	COG0051	transcription antitermination factor activity, RNA binding
J415_RS05435	COG0088	Forms part of the polypeptide exit tunnel
J415_RS05450	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J415_RS05465	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J415_RS05515	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J415_RS05530	COG0201	protein transport
J415_RS05545	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J415_RS05555	COG0202	RNA polymerase activity
J415_RS05560	COG0203	ribosomal protein L17
J415_RS05570	COG0789	Transcriptional regulator
J415_RS05600	COG0758	DNA mediated transformation
J415_RS05625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J415_RS05675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J415_RS05680	COG1309	transcriptional regulator
J415_RS05705	COG4145	pantothenate transmembrane transporter activity
J415_RS05710	COG3924	membrane
J415_RS05715	COG0439	Biotin carboxylase
J415_RS05720	COG0511	ligase activity, forming carbon-carbon bonds
J415_RS05740	COG0604	alcohol dehydrogenase
J415_RS05745	COG2200	EAL domain
J415_RS05745	COG2199	diguanylate cyclase activity
J415_RS05750	COG1077	Cell shape determining protein MreB Mrl
J415_RS05755	COG1792	Involved in formation and maintenance of cell shape
J415_RS05760	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J415_RS05775	COG3164	Protein of unknown function
J415_RS05780	COG0312	modulator of DNA gyrase
J415_RS05790	COG0583	DNA-binding transcription factor activity
J415_RS05805	COG1289	transmembrane transporter activity
J415_RS05810	COG2732	(Barnase) inhibitor
J415_RS05835	COG1802	Transcriptional regulator
J415_RS05845	COG0471	metal ion transport
J415_RS05850	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J415_RS05855	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J415_RS05865	COG0511	ligase activity, forming carbon-carbon bonds
J415_RS05865	COG5016	pyruvate
J415_RS05880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J415_RS05885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J415_RS05890	COG3105	Protein conserved in bacteria
J415_RS05895	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J415_RS05910	COG0625	glutathione transferase activity
J415_RS05915	COG2969	positive regulation of protein catabolic process
J415_RS05945	COG2731	YhcH YjgK YiaL family protein
J415_RS05950	COG0493	'glutamate synthase
J415_RS05955	COG0067	glutamate synthase
J415_RS05955	COG0069	glutamate synthase activity
J415_RS05955	COG0070	glutamate synthase
J415_RS05960	COG1242	4 iron, 4 sulfur cluster binding
J415_RS05965	COG0784	Response regulator, receiver
J415_RS05965	COG2198	Histidine kinase
J415_RS05965	COG5002	protein histidine kinase activity
J415_RS05970	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J415_RS05975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J415_RS05980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS05985	COG1660	Displays ATPase and GTPase activities
J415_RS05990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS05995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J415_RS06000	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J415_RS06005	COG1137	ATPase activity
J415_RS06010	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J415_RS06015	COG3117	lipopolysaccharide transmembrane transporter activity
J415_RS06020	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J415_RS06030	COG0530	calcium, potassium:sodium antiporter activity
J415_RS06035	COG1127	ABC transporter
J415_RS06040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J415_RS06045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J415_RS06050	COG2854	intermembrane phospholipid transfer
J415_RS06055	COG3113	response to antibiotic
J415_RS06060	COG5007	Belongs to the BolA IbaG family
J415_RS06070	COG3423	Transcriptional regulator
J415_RS06075	COG0142	geranyltranstransferase activity
J415_RS06090	COG0697	spore germination
J415_RS06100	COG2027	D-alanyl-D-alanine carboxypeptidase
J415_RS06110	COG1534	Rna-binding protein
J415_RS06120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J415_RS06125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J415_RS06135	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J415_RS06160	COG0195	Participates in both transcription termination and antitermination
J415_RS06165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J415_RS06195	COG0513	Belongs to the DEAD box helicase family
J415_RS06200	COG0814	amino acid
J415_RS06205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J415_RS06210	COG0826	peptidase U32
J415_RS06215	COG0826	peptidase U32
J415_RS06220	COG3154	lipid carrier protein
J415_RS06225	COG3153	acetyltransferase
J415_RS06230	COG2827	Endonuclease containing a URI domain
J415_RS06240	COG0693	protein deglycase activity
J415_RS06250	COG0701	Predicted permease
J415_RS06255	COG2823	Periplasmic or secreted lipoprotein
J415_RS06275	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J415_RS06290	COG1063	alcohol dehydrogenase
J415_RS06295	COG3775	system Galactitol-specific IIC component
J415_RS06300	COG3414	Phosphotransferase system galactitol-specific IIB component
J415_RS06305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS06310	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
J415_RS06315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS06315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS06320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS06320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS06320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS06335	COG1349	DNA-binding transcription factor activity
J415_RS06340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J415_RS06345	COG2721	sulfolactate sulfo-lyase activity
J415_RS06350	COG2271	Major facilitator Superfamily
J415_RS06360	COG2084	Dehydrogenase
J415_RS06365	COG1929	Belongs to the glycerate kinase type-1 family
J415_RS06375	COG1741	Belongs to the pirin family
J415_RS06380	COG0583	DNA-binding transcription factor activity
J415_RS06385	COG3152	Membrane
J415_RS06390	COG0435	Glutathione S-transferase
J415_RS06395	COG2259	Doxx family
J415_RS06405	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
J415_RS06410	COG4575	ribosome binding
J415_RS06415	COG1422	Protein of unknown function (DUF1090)
J415_RS06425	COG0586	Pfam SNARE associated Golgi protein
J415_RS06430	COG2186	Transcriptional regulator
J415_RS06435	COG2271	Major facilitator Superfamily
J415_RS06445	COG2721	sulfolactate sulfo-lyase activity
J415_RS06465	COG0673	inositol 2-dehydrogenase activity
J415_RS06470	COG1451	nucleotide metabolic process
J415_RS06475	COG3507	Belongs to the glycosyl hydrolase 43 family
J415_RS06485	COG2211	Major facilitator Superfamily
J415_RS06495	COG1902	pentaerythritol trinitrate reductase activity
J415_RS06495	COG0446	pyridine nucleotide-disulphide oxidoreductase
J415_RS06550	COG3408	Glycogen debranching enzyme
J415_RS06550	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
J415_RS06560	COG0531	amino acid
J415_RS06565	COG0531	amino acid
J415_RS06570	COG2731	YhcH YjgK YiaL family protein
J415_RS06575	COG3250	beta-galactosidase activity
J415_RS06580	COG1609	Transcriptional regulator
J415_RS06585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J415_RS06595	COG1695	Transcriptional regulator
J415_RS06600	COG2375	cellular response to nickel ion
J415_RS06615	COG1461	Dihydroxyacetone kinase
J415_RS06620	COG2376	Dihydroxyacetone kinase
J415_RS06670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J415_RS06725	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J415_RS06740	COG4991	sh3 domain protein
J415_RS06745	COG3025	triphosphatase activity
J415_RS06765	COG2960	long-chain fatty acid transporting porin activity
J415_RS06775	COG3539	Fimbrial protein
J415_RS06780	COG3121	Chaperone
J415_RS06790	COG3539	Fimbrial protein
J415_RS06800	COG3384	dioxygenase
J415_RS06805	COG0754	glutathionylspermidine amidase activity
J415_RS06820	COG0494	nUDIX hydrolase
J415_RS06825	COG3151	Protein conserved in bacteria
J415_RS06830	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J415_RS06835	COG3150	esterase
J415_RS06845	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J415_RS06850	COG2249	NAD(P)H dehydrogenase (quinone) activity
J415_RS06855	COG0642	Histidine kinase
J415_RS06860	COG0745	RESPONSE REGULATOR receiver
J415_RS06865	COG3111	PFAM Bacterial OB fold (BOF) protein
J415_RS06870	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
J415_RS06880	COG0204	Acyl-transferase
J415_RS06885	COG2132	Multicopper oxidase
J415_RS06890	COG1032	radical SAM domain protein
J415_RS06905	COG1979	alcohol dehydrogenase
J415_RS06910	COG2207	Transcriptional regulator
J415_RS06915	COG0586	Pfam SNARE associated Golgi protein
J415_RS06930	COG0848	biopolymer transport protein
J415_RS06950	COG0625	glutathione transferase activity
J415_RS06960	COG0754	glutathionylspermidine amidase activity
J415_RS06965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J415_RS06975	COG2365	Tyrosine phosphatase family
J415_RS06995	COG0626	cystathionine gamma-synthase activity
J415_RS07005	COG0471	metal ion transport
J415_RS07015	COG1811	Na channel or pump
J415_RS07020	COG1982	Orn Lys Arg decarboxylase major
J415_RS07025	COG2211	Major facilitator Superfamily
J415_RS07040	COG1194	a g-specific adenine glycosylase
J415_RS07050	COG3171	Protein conserved in bacteria
J415_RS07065	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J415_RS07070	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J415_RS07075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J415_RS07090	COG0762	integral membrane protein
J415_RS07095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J415_RS07100	COG2805	Type II/IV secretion system protein
J415_RS07105	COG3118	belongs to the thioredoxin family
J415_RS07110	COG2805	Type II/IV secretion system protein
J415_RS07115	COG2197	response regulator
J415_RS07135	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J415_RS07140	COG2356	endonuclease I
J415_RS07150	COG2814	Major facilitator Superfamily
J415_RS07170	COG0501	Belongs to the peptidase M48B family
J415_RS07175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J415_RS07180	COG1122	ATPase activity
J415_RS07215	COG0191	fructose-bisphosphate aldolase activity
J415_RS07220	COG0668	transmembrane transport
J415_RS07230	COG2968	Membrane
J415_RS07235	COG0583	DNA-binding transcription factor activity
J415_RS07240	COG0427	acetyl-CoA hydrolase
J415_RS07245	COG1024	Enoyl-CoA hydratase
J415_RS07250	COG1703	isobutyryl-CoA mutase activity
J415_RS07255	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J415_RS07255	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J415_RS07270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J415_RS07275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J415_RS07290	COG0006	proline dipeptidase activity
J415_RS07295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J415_RS07320	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS07325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J415_RS07330	COG2723	6-phospho-beta-galactosidase activity
J415_RS07335	COG1737	Transcriptional regulator
J415_RS07345	COG1272	protein, Hemolysin III
J415_RS07360	COG3716	PTS system mannose fructose sorbose family IID component
J415_RS07365	COG3715	PTS system
J415_RS07370	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS07370	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS07390	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J415_RS07400	COG0716	FMN binding
J415_RS07415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J415_RS07435	COG1811	Na channel or pump
J415_RS07450	COG0583	DNA-binding transcription factor activity
J415_RS07455	COG4942	peptidase
J415_RS07480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS07480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS07485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS07490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS07490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J415_RS07490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS07495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J415_RS07500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J415_RS07510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS07515	COG2207	Transcriptional regulator
J415_RS07520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS07525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J415_RS07525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS07525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS07530	COG0667	Aldo Keto reductase
J415_RS07535	COG0656	L-ascorbic acid biosynthetic process
J415_RS07560	COG0667	Aldo Keto reductase
J415_RS07570	COG0778	Nitroreductase
J415_RS07585	COG0667	Aldo Keto reductase
J415_RS07630	COG0583	DNA-binding transcription factor activity
J415_RS07640	COG2223	nitrite transmembrane transporter activity
J415_RS07650	COG1929	Belongs to the glycerate kinase type-1 family
J415_RS07695	COG0738	Major facilitator superfamily
J415_RS07700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J415_RS07705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J415_RS07710	COG1349	DNA-binding transcription factor activity
J415_RS07725	COG1349	DNA-binding transcription factor activity
J415_RS07750	COG2909	trisaccharide binding
J415_RS07755	COG1538	Outer membrane efflux protein
J415_RS07760	COG1289	transmembrane transporter activity
J415_RS07775	COG3592	Divergent 4Fe-4S mono-cluster
J415_RS07780	COG2388	GCN5-related N-acetyl-transferase
J415_RS07790	COG1522	sequence-specific DNA binding
J415_RS07795	COG1846	Transcriptional regulator
J415_RS07800	COG0697	spore germination
J415_RS07815	COG0640	Transcriptional regulator
J415_RS07860	COG0667	Aldo Keto reductase
J415_RS07865	COG0814	amino acid
J415_RS07880	COG0183	Belongs to the thiolase family
J415_RS07890	COG0823	Involved in the tonB-independent uptake of proteins
J415_RS07895	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS07900	COG2814	Major facilitator Superfamily
J415_RS07925	COG0823	Involved in the tonB-independent uptake of proteins
J415_RS07935	COG3842	ATPase activity
J415_RS07940	COG0395	ABC-type sugar transport system, permease component
J415_RS07945	COG1175	transmembrane transport
J415_RS07955	COG1794	racemase activity, acting on amino acids and derivatives
J415_RS07975	COG3188	usher protein
J415_RS07980	COG3121	Chaperone
J415_RS07985	COG0583	DNA-binding transcription factor activity
J415_RS07995	COG1609	Transcriptional regulator
J415_RS08000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J415_RS08005	COG2723	6-phospho-beta-galactosidase activity
J415_RS08010	COG2186	Transcriptional regulator
J415_RS08020	COG1609	Transcriptional regulator
J415_RS08035	COG0667	Aldo Keto reductase
J415_RS08045	COG0861	Integral membrane protein TerC family
J415_RS08080	COG2165	general secretion pathway protein
J415_RS08085	COG4795	General secretion pathway protein
J415_RS08095	COG4967	type IV pilus modification protein PilV
J415_RS08100	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J415_RS08105	COG1025	Belongs to the peptidase M16 family
J415_RS08110	COG1074	ATP-dependent DNA helicase activity
J415_RS08115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J415_RS08120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J415_RS08120	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J415_RS08125	COG0860	N-Acetylmuramoyl-L-alanine amidase
J415_RS08130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J415_RS08160	COG4656	Part of a membrane complex involved in electron transport
J415_RS08165	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS08165	COG1454	alcohol dehydrogenase
J415_RS08180	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
J415_RS08195	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
J415_RS08360	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J415_RS08365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J415_RS08370	COG2166	iron-sulfur cluster assembly
J415_RS08375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J415_RS08385	COG0583	DNA-binding transcription factor activity
J415_RS08390	COG2363	Small membrane protein
J415_RS08400	COG1349	DNA-binding transcription factor activity
J415_RS08420	COG0738	Major facilitator superfamily
J415_RS08425	COG0235	Class ii aldolase
J415_RS08440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J415_RS08455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J415_RS08460	COG1760	l-serine dehydratase
J415_RS08470	COG1611	Belongs to the LOG family
J415_RS08490	COG3098	single-species biofilm formation
J415_RS08495	COG0564	pseudouridine synthase activity
J415_RS08500	COG0716	FMN binding
J415_RS08505	COG2271	Major facilitator Superfamily
J415_RS08510	COG4948	Mandelate Racemase Muconate Lactonizing
J415_RS08515	COG4948	Mandelate Racemase Muconate Lactonizing
J415_RS08520	COG1929	Belongs to the glycerate kinase type-1 family
J415_RS08525	COG3850	Histidine kinase
J415_RS08525	COG2205	protein histidine kinase activity
J415_RS08525	COG4999	Histidine kinase
J415_RS08525	COG3437	response regulator, receiver
J415_RS08535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J415_RS08540	COG3956	TIGRFAM MazG family protein
J415_RS08560	COG0602	queuosine metabolic process
J415_RS08565	COG0720	synthase
J415_RS08590	COG2234	aminopeptidase activity
J415_RS08650	COG4942	peptidase
J415_RS08650	COG1388	LysM domain
J415_RS08655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J415_RS08665	COG0477	Major facilitator Superfamily
J415_RS08685	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J415_RS08705	COG3539	Fimbrial protein
J415_RS08715	COG3188	usher protein
J415_RS08720	COG3121	Chaperone
J415_RS08730	COG3539	Fimbrial protein
J415_RS08760	COG1132	(ABC) transporter
J415_RS08765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J415_RS08775	COG1538	Outer membrane efflux protein
J415_RS08780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J415_RS08820	COG1454	alcohol dehydrogenase
J415_RS08830	COG1063	alcohol dehydrogenase
J415_RS08850	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J415_RS08855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J415_RS08860	COG4558	Periplasmic binding protein
J415_RS08865	COG3720	iron ion transport
J415_RS08885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J415_RS08890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J415_RS08895	COG1121	(ABC) transporter
J415_RS08905	COG1609	Transcriptional regulator
J415_RS08910	COG1940	carbohydrate kinase activity
J415_RS08915	COG1447	Phosphotransferase system cellobiose-specific component IIA
J415_RS08920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J415_RS08925	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J415_RS08930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J415_RS08945	COG2723	6-phospho-beta-galactosidase activity
J415_RS08950	COG2755	lipolytic protein G-D-S-L family
J415_RS08950	COG0657	acetylesterase activity
J415_RS08960	COG0309	Hydrogenase expression formation protein (HypE)
J415_RS08965	COG0409	Hydrogenase expression formation protein
J415_RS08970	COG0298	carbon dioxide binding
J415_RS08975	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J415_RS08990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J415_RS08995	COG0651	ATP synthesis coupled electron transport
J415_RS09000	COG0650	Formate hydrogenlyase subunit 4
J415_RS09005	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
J415_RS09005	COG3261	NADH dehydrogenase
J415_RS09010	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J415_RS09015	COG3260	NADH ubiquinone oxidoreductase 20
J415_RS09025	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J415_RS09030	COG2723	6-phospho-beta-galactosidase activity
J415_RS09035	COG1263	PTS System
J415_RS09035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS09040	COG1609	Transcriptional regulator
J415_RS09050	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J415_RS09055	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
J415_RS09080	COG1349	DNA-binding transcription factor activity
J415_RS09085	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS09100	COG3732	PTS system glucitol sorbitol-specific
J415_RS09105	COG3730	PTS system glucitol sorbitol-specific
J415_RS09110	COG2951	lytic endotransglycosylase activity
J415_RS09120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J415_RS09125	COG0803	Belongs to the bacterial solute-binding protein 9 family
J415_RS09135	COG1546	Belongs to the CinA family
J415_RS09155	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
J415_RS09175	COG2823	Periplasmic or secreted lipoprotein
J415_RS09180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J415_RS09185	COG1238	metal cluster binding
J415_RS09205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J415_RS09210	COG2814	Major facilitator Superfamily
J415_RS09215	COG1566	PFAM secretion protein HlyD family protein
J415_RS09220	COG1846	Transcriptional regulator
J415_RS09230	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J415_RS09235	COG2113	Glycine betaine
J415_RS09240	COG4176	ABC-type proline glycine betaine transport system permease component
J415_RS09250	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J415_RS09255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J415_RS09265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J415_RS09270	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J415_RS09280	COG4575	ribosome binding
J415_RS09310	COG0640	Transcriptional regulator
J415_RS09315	COG3284	Transcriptional regulator
J415_RS09365	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS09370	COG2814	Major facilitator Superfamily
J415_RS09375	COG1858	cytochrome C peroxidase
J415_RS09385	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J415_RS09390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J415_RS09395	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J415_RS09405	COG1138	Cytochrome C-type biogenesis protein
J415_RS09410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J415_RS09415	COG3088	subunit of a heme lyase
J415_RS09415	COG4235	cytochrome complex assembly
J415_RS09425	COG0235	Class ii aldolase
J415_RS09430	COG1126	abc transporter atp-binding protein
J415_RS09435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS09635	COG2867	negative regulation of translational initiation
J415_RS09650	COG0497	DNA recombination
J415_RS09665	COG4536	flavin adenine dinucleotide binding
J415_RS09670	COG4137	Cytochrome C assembly protein
J415_RS09675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J415_RS09710	COG2885	chlorophyll binding
J415_RS09715	COG2199	diguanylate cyclase activity
J415_RS09725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J415_RS09730	COG1605	Chorismate mutase
J415_RS09730	COG0287	Prephenate dehydrogenase
J415_RS09740	COG1605	Chorismate mutase
J415_RS09740	COG0077	Prephenate dehydratase
J415_RS09745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J415_RS09750	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J415_RS09765	COG0542	response to heat
J415_RS09800	COG0477	Major facilitator Superfamily
J415_RS09805	COG5544	Lipoprotein
J415_RS09810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J415_RS09820	COG3148	PFAM DTW domain containing protein
J415_RS09825	COG3118	belongs to the thioredoxin family
J415_RS09830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J415_RS09845	COG0513	Belongs to the DEAD box helicase family
J415_RS09855	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J415_RS09865	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
J415_RS09875	COG3086	response to oxidative stress
J415_RS09885	COG0681	Belongs to the peptidase S26 family
J415_RS09905	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J415_RS09915	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J415_RS09920	COG1737	Transcriptional regulator
J415_RS09925	COG0560	Phosphoserine phosphatase
J415_RS09940	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J415_RS09940	COG0047	phosphoribosylformylglycinamidine synthase activity
J415_RS09945	COG2205	protein histidine kinase activity
J415_RS09950	COG3170	Tfp pilus assembly protein FimV
J415_RS09955	COG2204	response regulator
J415_RS09960	COG0347	Belongs to the P(II) protein family
J415_RS09965	COG0371	Dehydrogenase
J415_RS09970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J415_RS09990	COG1609	Transcriptional regulator
J415_RS09995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J415_RS09995	COG1017	nitric oxide dioxygenase activity
J415_RS10005	COG2259	Doxx family
J415_RS10010	COG1940	carbohydrate kinase activity
J415_RS10015	COG0457	Tetratricopeptide repeat
J415_RS10020	COG2814	Major facilitator Superfamily
J415_RS10020	COG0477	Major facilitator Superfamily
J415_RS10030	COG2814	Major facilitator Superfamily
J415_RS10035	COG3711	transcriptional antiterminator
J415_RS10040	COG3683	transport system, periplasmic component
J415_RS10075	COG0822	iron-sulfur transferase activity
J415_RS10095	COG0633	Ferredoxin
J415_RS10100	COG2975	iron-sulfur cluster assembly
J415_RS10115	COG2897	thiosulfate sulfurtransferase activity
J415_RS10120	COG1473	amidohydrolase
J415_RS10130	COG2373	Large extracellular alpha-helical protein
J415_RS10135	COG4953	penicillin-binding protein 1C
J415_RS10165	COG2976	Protein conserved in bacteria
J415_RS10325	COG1645	bacterial-type flagellum-dependent swarming motility
J415_RS10340	COG1570	exodeoxyribonuclease VII activity
J415_RS10345	COG0517	IMP dehydrogenase activity
J415_RS10345	COG0516	GMP reductase activity
J415_RS10350	COG0519	Catalyzes the synthesis of GMP from XMP
J415_RS10350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J415_RS10360	COG0583	DNA-binding transcription factor activity
J415_RS10370	COG2200	EAL domain
J415_RS10375	COG0248	Ppx GppA phosphatase
J415_RS10395	COG2211	Major facilitator Superfamily
J415_RS10405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J415_RS10420	COG2723	6-phospho-beta-galactosidase activity
J415_RS10425	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J415_RS10430	COG2233	PERMEase
J415_RS10440	COG1393	Belongs to the ArsC family
J415_RS10445	COG4783	chaperone-mediated protein folding
J415_RS10450	COG0628	permease
J415_RS10455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J415_RS10460	COG2716	regulation of RNA biosynthetic process
J415_RS10470	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J415_RS10480	COG2321	neutral zinc metallopeptidase
J415_RS10490	COG0400	carboxylic ester hydrolase activity
J415_RS10505	COG1393	Belongs to the ArsC family
J415_RS10510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J415_RS10515	COG0493	'glutamate synthase
J415_RS10515	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J415_RS10525	COG5342	invasion associated locus B
J415_RS10530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J415_RS10540	COG4810	utilization protein
J415_RS10550	COG4766	ethanolamine catabolic process
J415_RS10620	COG2207	Transcriptional regulator
J415_RS10630	COG0860	N-Acetylmuramoyl-L-alanine amidase
J415_RS10650	COG2837	iron assimilation
J415_RS10655	COG4150	thiosulfate binding
J415_RS10660	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J415_RS10665	COG4208	sulfate ABC transporter
J415_RS10670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J415_RS10680	COG4319	ketosteroid isomerase
J415_RS10745	COG3530	Putative quorum-sensing-regulated virulence factor
J415_RS10750	COG0385	Bile acid
J415_RS10755	COG0583	DNA-binding transcription factor activity
J415_RS10760	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J415_RS10765	COG2211	Major facilitator Superfamily
J415_RS10770	COG0583	DNA-binding transcription factor activity
J415_RS10800	COG3415	Transposase
J415_RS10805	COG3415	Transposase
J415_RS10820	COG2200	EAL domain
J415_RS10820	COG2199	diguanylate cyclase activity
J415_RS10825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J415_RS10840	COG0667	Aldo Keto reductase
J415_RS10845	COG3961	Belongs to the TPP enzyme family
J415_RS10860	COG3279	Response regulator of the LytR AlgR family
J415_RS10865	COG3275	phosphorelay sensor kinase activity
J415_RS10870	COG0436	Aminotransferase
J415_RS10875	COG2807	transmembrane transport
J415_RS10880	COG0583	DNA-binding transcription factor activity
J415_RS10905	COG2116	formate transmembrane transporter activity
J415_RS10920	COG3691	Protein conserved in bacteria
J415_RS10935	COG2062	phosphohistidine phosphatase, SixA
J415_RS10960	COG0730	response to heat
J415_RS10965	COG3101	peptidyl-lysine hydroxylation
J415_RS10980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J415_RS11000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J415_RS11010	COG0586	Pfam SNARE associated Golgi protein
J415_RS11020	COG0285	dihydrofolate synthase activity
J415_RS11025	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J415_RS11030	COG1286	toxin biosynthetic process
J415_RS11035	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J415_RS11040	COG0163	prenyltransferase activity
J415_RS11060	COG4160	amino acid transport
J415_RS11065	COG4598	ABC transporter
J415_RS11085	COG1090	epimerase
J415_RS11090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J415_RS11095	COG0625	glutathione transferase activity
J415_RS11100	COG0625	glutathione transferase activity
J415_RS11105	COG0622	Phosphoesterase
J415_RS11115	COG1609	Transcriptional regulator
J415_RS11120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS11130	COG3037	sugar-specific permease SgaT UlaA
J415_RS11135	COG3959	Transketolase, thiamine diphosphate binding domain
J415_RS11140	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J415_RS11165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J415_RS11170	COG0490	domain, Protein
J415_RS11170	COG0471	metal ion transport
J415_RS11180	COG0436	Aminotransferase
J415_RS11185	COG0583	DNA-binding transcription factor activity
J415_RS11230	COG0839	Belongs to the complex I subunit 6 family
J415_RS11235	COG0713	ATP synthesis coupled electron transport
J415_RS11240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J415_RS11245	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J415_RS11255	COG0582	viral genome integration into host DNA
J415_RS11265	COG3121	Chaperone
J415_RS11285	COG0582	viral genome integration into host DNA
J415_RS11295	COG2153	protein acetylation
J415_RS11300	COG1169	isochorismate synthase
J415_RS11335	COG3647	Membrane
J415_RS11390	COG1414	Transcriptional regulator
J415_RS11400	COG2271	Major facilitator Superfamily
J415_RS11410	COG0247	lactate metabolic process
J415_RS11420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J415_RS11425	COG2271	Major facilitator Superfamily
J415_RS11430	COG0584	glycerophosphoryl diester phosphodiesterase
J415_RS11435	COG0583	DNA-binding transcription factor activity
J415_RS11440	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
J415_RS11445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J415_RS11470	COG2205	protein histidine kinase activity
J415_RS11470	COG0784	Response regulator, receiver
J415_RS11480	COG2198	Histidine kinase
J415_RS11480	COG0642	Histidine kinase
J415_RS11500	COG3145	DNA-N1-methyladenine dioxygenase activity
J415_RS11505	COG4615	Cyclic peptide transporter
J415_RS11510	COG2239	Acts as a magnesium transporter
J415_RS11515	COG0659	secondary active sulfate transmembrane transporter activity
J415_RS11530	COG0628	permease
J415_RS11595	COG1349	DNA-binding transcription factor activity
J415_RS11600	COG0494	nUDIX hydrolase
J415_RS11610	COG1061	Type III restriction enzyme res subunit
J415_RS11615	COG1187	pseudouridine synthase activity
J415_RS11620	COG2814	Major facilitator Superfamily
J415_RS11630	COG4172	Belongs to the ABC transporter superfamily
J415_RS11635	COG4239	(ABC) transporter, permease
J415_RS11640	COG4174	ABC transporter (Permease)
J415_RS11645	COG4166	transmembrane transport
J415_RS11650	COG2200	EAL domain
J415_RS11655	COG0791	NLP P60 protein
J415_RS11660	COG0671	phosphoesterase, PA-phosphatase related
J415_RS11665	COG0523	cobalamin synthesis protein
J415_RS11670	COG0246	Mannitol dehydrogenase
J415_RS11675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J415_RS11685	COG2814	Major facilitator Superfamily
J415_RS11690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS11690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS11695	COG1105	Belongs to the carbohydrate kinase PfkB family
J415_RS11700	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J415_RS11700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS11700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS11705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J415_RS11710	COG2313	pseudouridylate synthase activity
J415_RS11720	COG1522	sequence-specific DNA binding
J415_RS11720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J415_RS11730	COG2855	membrane
J415_RS11735	COG0583	DNA-binding transcription factor activity
J415_RS11740	COG0833	amino acid
J415_RS11745	COG4771	TonB-dependent receptor
J415_RS11760	COG2311	Membrane
J415_RS11775	COG1129	ABC transporter
J415_RS11785	COG2949	membrane
J415_RS11795	COG1346	cytolysis
J415_RS11805	COG0583	DNA-binding transcription factor activity
J415_RS11810	COG2271	Major facilitator Superfamily
J415_RS11825	COG0625	glutathione transferase activity
J415_RS11830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J415_RS11835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J415_RS11850	COG2723	6-phospho-beta-galactosidase activity
J415_RS11855	COG2226	methyltransferase
J415_RS11860	COG1538	Outer membrane efflux protein
J415_RS11865	COG0586	Pfam SNARE associated Golgi protein
J415_RS11880	COG1686	Belongs to the peptidase S11 family
J415_RS11890	COG0277	FAD linked oxidase domain protein
J415_RS11895	COG1472	Belongs to the glycosyl hydrolase 3 family
J415_RS11900	COG1732	Glycine betaine
J415_RS11905	COG1174	glycine betaine transport
J415_RS11910	COG1125	glycine betaine transport
J415_RS11915	COG1174	glycine betaine transport
J415_RS11920	COG0789	Transcriptional regulator
J415_RS11925	COG3275	phosphorelay sensor kinase activity
J415_RS11935	COG4807	Protein conserved in bacteria
J415_RS11940	COG4808	Protein conserved in bacteria
J415_RS11960	COG5455	response to cobalt ion
J415_RS11965	COG0583	DNA-binding transcription factor activity
J415_RS11970	COG2252	PERMEase
J415_RS11980	COG0583	DNA-binding transcription factor activity
J415_RS11990	COG2015	COG2015, Alkyl sulfatase and related hydrolases
J415_RS12000	COG0351	phosphomethylpyrimidine kinase
J415_RS12005	COG2188	Transcriptional regulator
J415_RS12010	COG2188	Transcriptional regulator
J415_RS12015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J415_RS12020	COG1397	ADP-ribosylglycohydrolase
J415_RS12025	COG2211	Major facilitator Superfamily
J415_RS12030	COG1830	Aldolase
J415_RS12060	COG1070	Carbohydrate kinase
J415_RS12070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J415_RS12075	COG4948	Mandelate Racemase Muconate Lactonizing
J415_RS12080	COG0747	negative chemotaxis
J415_RS12085	COG0601	transmembrane transport
J415_RS12090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J415_RS12095	COG0444	Belongs to the ABC transporter superfamily
J415_RS12100	COG4608	Belongs to the ABC transporter superfamily
J415_RS12120	COG0826	peptidase U32
J415_RS12125	COG0745	RESPONSE REGULATOR receiver
J415_RS12130	COG2205	protein histidine kinase activity
J415_RS12160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS12175	COG1522	sequence-specific DNA binding
J415_RS12185	COG2267	carboxylic ester hydrolase activity
J415_RS12200	COG0601	transmembrane transport
J415_RS12205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J415_RS12210	COG0444	Belongs to the ABC transporter superfamily
J415_RS12215	COG4608	Belongs to the ABC transporter superfamily
J415_RS12225	COG1301	dicarboxylic acid transport
J415_RS12240	COG2205	protein histidine kinase activity
J415_RS12245	COG0372	Belongs to the citrate synthase family
J415_RS12250	COG0443	Heat shock 70 kDa protein
J415_RS12255	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J415_RS12270	COG2982	Protein involved in outer membrane biogenesis
J415_RS12275	COG1253	flavin adenine dinucleotide binding
J415_RS12340	COG2244	polysaccharide biosynthetic process
J415_RS12350	COG1088	dTDP-glucose 4,6-dehydratase activity
J415_RS12360	COG1091	dTDP-4-dehydrorhamnose reductase activity
J415_RS12410	COG1215	transferase activity, transferring glycosyl groups
J415_RS12420	COG0107	imidazoleglycerol-phosphate synthase activity
J415_RS12430	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J415_RS12445	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J415_RS12455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J415_RS12460	COG0583	DNA-binding transcription factor activity
J415_RS12465	COG0531	amino acid
J415_RS12480	COG3604	Transcriptional regulator
J415_RS12485	COG2205	protein histidine kinase activity
J415_RS12570	COG0640	Transcriptional regulator
J415_RS12580	COG2925	Exonuclease
J415_RS12600	COG1289	transmembrane transporter activity
J415_RS12620	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J415_RS12630	COG2814	Major facilitator Superfamily
J415_RS12635	COG0673	inositol 2-dehydrogenase activity
J415_RS12640	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS12640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS12645	COG1082	Xylose isomerase domain protein TIM barrel
J415_RS12655	COG1942	4-Oxalocrotonate Tautomerase
J415_RS12660	COG0583	DNA-binding transcription factor activity
J415_RS12665	COG0095	Lipoate-protein ligase
J415_RS12670	COG0477	Major facilitator Superfamily
J415_RS12680	COG3300	MHYT domain
J415_RS12680	COG5001	Diguanylate cyclase
J415_RS12685	COG3615	Tellurite resistance protein tehB
J415_RS12695	COG2188	Transcriptional regulator
J415_RS12700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS12700	COG1263	PTS System
J415_RS12715	COG3539	Fimbrial protein
J415_RS12720	COG3539	Fimbrial protein
J415_RS12725	COG3539	Fimbrial protein
J415_RS12730	COG3188	usher protein
J415_RS12735	COG3121	Chaperone
J415_RS12740	COG3539	Fimbrial protein
J415_RS12780	COG1376	ErfK ybiS ycfS ynhG family protein
J415_RS12795	COG0667	Aldo Keto reductase
J415_RS12800	COG0583	DNA-binding transcription factor activity
J415_RS12840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J415_RS12845	COG0604	alcohol dehydrogenase
J415_RS12850	COG0583	DNA-binding transcription factor activity
J415_RS12915	COG2814	Major facilitator Superfamily
J415_RS12965	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J415_RS12970	COG0583	DNA-binding transcription factor activity
J415_RS12975	COG1486	melibiose metabolic process
J415_RS12980	COG3118	belongs to the thioredoxin family
J415_RS12985	COG2207	Transcriptional regulator
J415_RS12990	COG1881	PFAM PEBP family protein
J415_RS12995	COG1902	pentaerythritol trinitrate reductase activity
J415_RS13005	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS13025	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J415_RS13030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J415_RS13035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J415_RS13050	COG3414	Phosphotransferase system galactitol-specific IIB component
J415_RS13055	COG3775	system Galactitol-specific IIC component
J415_RS13060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J415_RS13070	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J415_RS13075	COG1129	ABC transporter
J415_RS13080	COG1879	ABC-type sugar transport system periplasmic component
J415_RS13085	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS13090	COG1070	Carbohydrate kinase
J415_RS13095	COG0582	viral genome integration into host DNA
J415_RS13105	COG0534	Mate efflux family protein
J415_RS13140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J415_RS13170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J415_RS13180	COG0589	response to stress
J415_RS13190	COG2819	hydrolase of the alpha beta superfamily
J415_RS13210	COG0251	oxidation-reduction process
J415_RS13240	COG0463	Glycosyl transferase, family 2
J415_RS13245	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J415_RS13255	COG1418	mRNA catabolic process
J415_RS13260	COG0270	DNA (cytosine-5-)-methyltransferase activity
J415_RS13265	COG3727	T/G mismatch-specific endonuclease activity
J415_RS13270	COG0697	spore germination
J415_RS13275	COG2354	Protein conserved in bacteria
J415_RS13280	COG5475	Uncharacterized small protein (DUF2158)
J415_RS13315	COG0366	Alpha amylase catalytic
J415_RS13320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS13330	COG0765	amino acid transport
J415_RS13335	COG1126	abc transporter atp-binding protein
J415_RS13340	COG2197	response regulator
J415_RS13350	COG2197	response regulator
J415_RS13380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J415_RS13385	COG3318	Belongs to the UPF0149 family
J415_RS13385	COG3012	SEC-C Motif Domain Protein
J415_RS13390	COG0814	amino acid
J415_RS13400	COG1528	Iron-storage protein
J415_RS13410	COG0477	Major facilitator Superfamily
J415_RS13425	COG1528	Iron-storage protein
J415_RS13435	COG1879	ABC-type sugar transport system periplasmic component
J415_RS13445	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS13470	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
J415_RS13480	COG3102	Protein conserved in bacteria
J415_RS13505	COG3788	relative of glutathione S-transferase, MAPEG superfamily
J415_RS13510	COG1801	Protein of unknown function DUF72
J415_RS13515	COG1335	isochorismatase
J415_RS13525	COG0494	nUDIX hydrolase
J415_RS13530	COG0217	transcriptional regulatory protein
J415_RS13550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J415_RS13560	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J415_RS13565	COG0739	heme binding
J415_RS13570	COG1560	Kdo2-lipid A biosynthetic process
J415_RS13580	COG0281	malic enzyme
J415_RS13585	COG0679	Auxin Efflux Carrier
J415_RS13590	COG3493	citrate carrier protein
J415_RS13600	COG1737	Transcriptional regulator
J415_RS13605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J415_RS13610	COG0129	dihydroxy-acid dehydratase activity
J415_RS13615	COG0800	Aldolase
J415_RS13625	COG3141	response to X-ray
J415_RS13630	COG2979	Protein of unknown function (DUF533)
J415_RS13635	COG1770	oligopeptidase
J415_RS13640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J415_RS13650	COG2372	response to copper ion
J415_RS13655	COG1276	copper resistance
J415_RS13715	COG3008	intermembrane lipid transfer
J415_RS13720	COG2995	paraquat-inducible protein a
J415_RS13725	COG1956	GAF domain-containing protein
J415_RS13745	COG2814	Major facilitator Superfamily
J415_RS13750	COG1414	Transcriptional regulator
J415_RS13775	COG0768	penicillin binding
J415_RS13780	COG2226	methyltransferase
J415_RS13800	COG3716	PTS system mannose fructose sorbose family IID component
J415_RS13805	COG3715	PTS system
J415_RS13810	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS13810	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS13815	COG1253	flavin adenine dinucleotide binding
J415_RS13820	COG2200	EAL domain
J415_RS13825	COG1760	l-serine dehydratase
J415_RS13860	COG1175	transmembrane transport
J415_RS13865	COG0395	ABC-type sugar transport system, permease component
J415_RS13870	COG3842	ATPase activity
J415_RS13880	COG0251	oxidation-reduction process
J415_RS13885	COG1199	ATP-dependent helicase activity
J415_RS13890	COG1214	PFAM Peptidase M22, glycoprotease
J415_RS13895	COG3065	identical protein binding
J415_RS13905	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J415_RS13915	COG2894	cell division
J415_RS13930	COG0179	Fumarylacetoacetate (FAA) hydrolase
J415_RS13960	COG2719	SpoVR family
J415_RS13980	COG1619	proteins homologs of microcin C7 resistance protein MccF
J415_RS13995	COG2211	Major facilitator Superfamily
J415_RS14005	COG1472	Belongs to the glycosyl hydrolase 3 family
J415_RS14015	COG2308	Evidence 4 Homologs of previously reported genes of
J415_RS14040	COG2814	Major facilitator Superfamily
J415_RS14055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J415_RS14065	COG1174	glycine betaine transport
J415_RS14080	COG0564	pseudouridine synthase activity
J415_RS14085	COG0583	DNA-binding transcription factor activity
J415_RS14105	COG2351	hydroxyisourate hydrolase activity
J415_RS14110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS14110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS14115	COG2814	Major facilitator Superfamily
J415_RS14130	COG2068	MobA-Related Protein
J415_RS14135	COG3383	formate dehydrogenase (NAD+) activity
J415_RS14140	COG3383	formate dehydrogenase (NAD+) activity
J415_RS14145	COG2233	PERMEase
J415_RS14150	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J415_RS14150	COG0493	'glutamate synthase
J415_RS14155	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J415_RS14160	COG0402	S-adenosylhomocysteine deaminase activity
J415_RS14165	COG0493	'glutamate synthase
J415_RS14165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J415_RS14170	COG3608	succinylglutamate desuccinylase aspartoacylase
J415_RS14170	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
J415_RS14175	COG0549	Belongs to the carbamate kinase family
J415_RS14185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J415_RS14190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J415_RS14195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J415_RS14200	COG3829	transcription factor binding
J415_RS14210	COG0582	viral genome integration into host DNA
J415_RS14215	COG0012	GTP binding
J415_RS14235	COG0659	secondary active sulfate transmembrane transporter activity
J415_RS14265	COG2890	protein-(glutamine-N5) methyltransferase activity
J415_RS14285	COG0387	Pfam Sodium calcium exchanger
J415_RS14290	COG4572	Cation transport regulator
J415_RS14295	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
J415_RS14305	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J415_RS14310	COG3707	response regulator
J415_RS14315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J415_RS14325	COG1116	anion transmembrane transporter activity
J415_RS14340	COG0243	molybdopterin cofactor binding
J415_RS14345	COG4932	domain protein
J415_RS14350	COG2197	response regulator
J415_RS14355	COG3850	Histidine kinase
J415_RS14360	COG2223	nitrite transmembrane transporter activity
J415_RS14365	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
J415_RS14370	COG1140	nitrate reductase beta subunit
J415_RS14375	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
J415_RS14380	COG2181	nitrate reductase activity
J415_RS14395	COG0788	formyltetrahydrofolate deformylase activity
J415_RS14405	COG1752	Esterase of the alpha-beta hydrolase superfamily
J415_RS14410	COG0745	RESPONSE REGULATOR receiver
J415_RS14415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J415_RS14430	COG1454	alcohol dehydrogenase
J415_RS14430	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS14435	COG2095	MarC family integral membrane protein
J415_RS14445	COG0601	transmembrane transport
J415_RS14450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J415_RS14455	COG0444	Belongs to the ABC transporter superfamily
J415_RS14465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J415_RS14485	COG1902	pentaerythritol trinitrate reductase activity
J415_RS14490	COG2350	Protein conserved in bacteria
J415_RS14500	COG3001	Fructosamine kinase
J415_RS14510	COG1105	Belongs to the carbohydrate kinase PfkB family
J415_RS14515	COG3137	Salt-induced outer membrane protein
J415_RS14540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J415_RS14550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J415_RS14550	COG0072	phenylalanine-tRNA ligase activity
J415_RS14570	COG0386	Belongs to the glutathione peroxidase family
J415_RS14580	COG0791	NLP P60 protein
J415_RS14590	COG4256	Hemin uptake protein
J415_RS14595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J415_RS14605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J415_RS14605	COG0574	Belongs to the PEP-utilizing enzyme family
J415_RS14610	COG0628	permease
J415_RS14615	COG0247	lactate metabolic process
J415_RS14615	COG0277	FAD linked oxidase domain protein
J415_RS14620	COG2050	protein possibly involved in aromatic compounds catabolism
J415_RS14625	COG2261	transglycosylase associated protein
J415_RS14630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J415_RS14645	COG3121	Chaperone
J415_RS14660	COG3539	Fimbrial protein
J415_RS14665	COG0316	Belongs to the HesB IscA family
J415_RS14670	COG0719	Fe-S assembly protein
J415_RS14675	COG0396	ATPase activity
J415_RS14680	COG0719	Fe-S assembly protein
J415_RS14695	COG1376	ErfK ybiS ycfS ynhG family protein
J415_RS14720	COG3185	4-Hydroxyphenylpyruvate dioxygenase
J415_RS14720	COG1082	Xylose isomerase domain protein TIM barrel
J415_RS14725	COG2271	Major facilitator Superfamily
J415_RS14730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J415_RS14740	COG1120	ATPase activity
J415_RS14745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J415_RS14750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J415_RS14755	COG1414	Transcriptional regulator
J415_RS14790	COG2814	Major facilitator Superfamily
J415_RS14820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J415_RS14840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J415_RS14845	COG1116	anion transmembrane transporter activity
J415_RS14850	COG4774	siderophore transport
J415_RS14855	COG1120	ATPase activity
J415_RS14860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J415_RS14865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J415_RS14885	COG0765	amino acid transport
J415_RS14890	COG1126	abc transporter atp-binding protein
J415_RS14900	COG1473	amidohydrolase
J415_RS14905	COG3383	formate dehydrogenase (NAD+) activity
J415_RS14910	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J415_RS14975	COG1175	transmembrane transport
J415_RS14980	COG3842	ATPase activity
J415_RS15005	COG1278	Cold shock
J415_RS15025	COG0582	viral genome integration into host DNA
J415_RS15030	COG3539	Fimbrial protein
J415_RS15045	COG3121	Chaperone
J415_RS15055	COG0582	viral genome integration into host DNA
J415_RS15060	COG4993	Dehydrogenase
J415_RS15070	COG0444	Belongs to the ABC transporter superfamily
J415_RS15085	COG4166	transmembrane transport
J415_RS15095	COG0346	lactoylglutathione lyase activity
J415_RS15115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J415_RS15120	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS15125	COG3111	PFAM Bacterial OB fold (BOF) protein
J415_RS15130	COG4529	Protein conserved in bacteria
J415_RS15145	COG2323	membrane
J415_RS15150	COG1546	Belongs to the CinA family
J415_RS15165	COG1294	oxidase, subunit
J415_RS15170	COG1271	oxidase subunit
J415_RS15175	COG3546	catalase activity
J415_RS15180	COG3685	Protein conserved in bacteria
J415_RS15185	COG3685	Protein conserved in bacteria
J415_RS15190	COG3729	General stress protein
J415_RS15215	COG0307	riboflavin synthase, alpha
J415_RS15220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J415_RS15225	COG2814	Major facilitator Superfamily
J415_RS15230	COG0583	DNA-binding transcription factor activity
J415_RS15240	COG2814	Major facilitator Superfamily
J415_RS15250	COG0791	NLP P60 protein
J415_RS15255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J415_RS15265	COG0346	lactoylglutathione lyase activity
J415_RS15275	COG1309	transcriptional regulator
J415_RS15280	COG3313	Fe-S protein
J415_RS15285	COG4989	oxidoreductase activity
J415_RS15295	COG1289	transmembrane transporter activity
J415_RS15300	COG1566	PFAM secretion protein HlyD family protein
J415_RS15315	COG3706	GGDEF domain
J415_RS15350	COG0625	glutathione transferase activity
J415_RS15360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J415_RS15370	COG4659	FMN binding
J415_RS15405	COG2723	6-phospho-beta-galactosidase activity
J415_RS15415	COG0673	inositol 2-dehydrogenase activity
J415_RS15430	COG0425	Belongs to the sulfur carrier protein TusA family
J415_RS15435	COG2391	methyltransferase activity
J415_RS15445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J415_RS15450	COG1263	PTS System
J415_RS15450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS15455	COG1609	Transcriptional regulator
J415_RS15460	COG5339	Protein conserved in bacteria
J415_RS15465	COG1482	cell wall glycoprotein biosynthetic process
J415_RS15470	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J415_RS15470	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J415_RS15475	COG0114	fumarate hydratase activity
J415_RS15485	COG2205	protein histidine kinase activity
J415_RS15495	COG0386	Belongs to the glutathione peroxidase family
J415_RS15505	COG0745	RESPONSE REGULATOR receiver
J415_RS15515	COG3136	membrane protein required for alginate biosynthesis
J415_RS15525	COG0531	amino acid
J415_RS15535	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J415_RS15540	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J415_RS15550	COG0589	response to stress
J415_RS15555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J415_RS15560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J415_RS15565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J415_RS15570	COG1473	amidohydrolase
J415_RS15580	COG0583	DNA-binding transcription factor activity
J415_RS15585	COG2840	Smr protein MutS2
J415_RS15590	COG1414	Transcriptional regulator
J415_RS15600	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J415_RS15605	COG0183	Belongs to the thiolase family
J415_RS15615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J415_RS15620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J415_RS15625	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J415_RS15625	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J415_RS15645	COG4565	transcriptional regulatory protein
J415_RS15650	COG3290	protein histidine kinase activity
J415_RS15660	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS15665	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J415_RS15680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J415_RS15690	COG0679	Auxin Efflux Carrier
J415_RS15720	COG0628	permease
J415_RS15740	COG3591	Belongs to the peptidase S1B family
J415_RS15750	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J415_RS15755	COG2814	Major facilitator Superfamily
J415_RS15760	COG0583	DNA-binding transcription factor activity
J415_RS15765	COG1940	carbohydrate kinase activity
J415_RS15770	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J415_RS15780	COG3381	protein complex oligomerization
J415_RS15785	COG3302	dmso reductase anchor subunit
J415_RS15790	COG0437	4 iron, 4 sulfur cluster binding
J415_RS15795	COG0243	molybdopterin cofactor binding
J415_RS15810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J415_RS15825	COG4948	Mandelate Racemase Muconate Lactonizing
J415_RS15830	COG1063	alcohol dehydrogenase
J415_RS15835	COG0477	Major facilitator Superfamily
J415_RS15840	COG0246	Mannitol dehydrogenase
J415_RS15845	COG0589	response to stress
J415_RS15850	COG1802	Transcriptional regulator
J415_RS15855	COG4221	oxidoreductase activity
J415_RS15860	COG0339	signal peptide processing
J415_RS15885	COG3122	Protein conserved in bacteria
J415_RS15910	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J415_RS15915	COG2223	nitrite transmembrane transporter activity
J415_RS15975	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J415_RS16010	COG2814	Major facilitator Superfamily
J415_RS16015	COG0697	spore germination
J415_RS16055	COG0039	L-malate dehydrogenase activity
J415_RS16065	COG0583	DNA-binding transcription factor activity
J415_RS16070	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS16085	COG2199	diguanylate cyclase activity
J415_RS16130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J415_RS16135	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J415_RS16185	COG2011	ABC-type metal ion transport system permease component
J415_RS16205	COG4628	conserved protein (DUF2132)
J415_RS16220	COG1126	abc transporter atp-binding protein
J415_RS16225	COG0765	amino acid transport
J415_RS16250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J415_RS16255	COG2207	Transcriptional regulator
J415_RS16265	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J415_RS16270	COG1446	asparaginase
J415_RS16275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J415_RS16290	COG1120	ATPase activity
J415_RS16295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J415_RS16300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J415_RS16320	COG3775	system Galactitol-specific IIC component
J415_RS16325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J415_RS16330	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS16335	COG1070	Carbohydrate kinase
J415_RS16360	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS16375	COG1609	Transcriptional regulator
J415_RS16385	COG0693	protein deglycase activity
J415_RS16400	COG0412	Dienelactone hydrolase
J415_RS16405	COG0583	DNA-binding transcription factor activity
J415_RS16430	COG2841	Protein conserved in bacteria
J415_RS16465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS16480	COG4821	SIS domain
J415_RS16525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J415_RS16555	COG3391	amine dehydrogenase activity
J415_RS16560	COG4771	TonB-dependent receptor
J415_RS16570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J415_RS16585	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS16595	COG1609	Transcriptional regulator
J415_RS16650	COG1652	LysM domain
J415_RS16655	COG4771	TonB-dependent receptor
J415_RS16660	COG1021	2,3-dihydroxybenzoate-AMP ligase
J415_RS16680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J415_RS16680	COG3433	isochorismatase activity
J415_RS16680	COG2226	methyltransferase
J415_RS16690	COG1132	(ABC) transporter
J415_RS16690	COG2375	cellular response to nickel ion
J415_RS16695	COG1132	(ABC) transporter
J415_RS16700	COG2814	Major facilitator Superfamily
J415_RS16705	COG1169	isochorismate synthase
J415_RS16710	COG0814	amino acid
J415_RS16715	COG1760	l-serine dehydratase
J415_RS16745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS16750	COG0765	amino acid transport
J415_RS16755	COG1126	abc transporter atp-binding protein
J415_RS16835	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J415_RS16840	COG0022	dehydrogenase e1 component
J415_RS16845	COG0508	dehydrogenase complex catalyzes the overall conversion of
J415_RS16850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J415_RS16875	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS16895	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J415_RS16900	COG2200	EAL domain
J415_RS16900	COG2771	luxR family
J415_RS16905	COG1649	PFAM Uncharacterised BCR, COG1649
J415_RS16945	COG1609	Transcriptional regulator
J415_RS16950	COG1082	Xylose isomerase domain protein TIM barrel
J415_RS16955	COG0673	inositol 2-dehydrogenase activity
J415_RS16960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J415_RS16965	COG1116	anion transmembrane transporter activity
J415_RS16970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J415_RS16980	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J415_RS16985	COG0076	glutamate decarboxylase activity
J415_RS17000	COG0519	Catalyzes the synthesis of GMP from XMP
J415_RS17000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J415_RS17015	COG0439	Biotin carboxylase
J415_RS17030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J415_RS17030	COG1116	anion transmembrane transporter activity
J415_RS17055	COG1280	lysine exporter protein (LysE YggA)
J415_RS17095	COG2271	Major facilitator Superfamily
J415_RS17105	COG0583	DNA-binding transcription factor activity
J415_RS17110	COG0583	DNA-binding transcription factor activity
J415_RS17120	COG1280	lysine exporter protein (LysE YggA)
J415_RS17125	COG0243	molybdopterin cofactor binding
J415_RS17130	COG3781	membrane
J415_RS17145	COG1764	response to oxidative stress
J415_RS17175	COG0488	(ABC) transporter
J415_RS17190	COG1064	alcohol dehydrogenase
J415_RS17210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J415_RS17230	COG2814	Major facilitator Superfamily
J415_RS17240	COG2864	formate dehydrogenase
J415_RS17245	COG0437	4 iron, 4 sulfur cluster binding
J415_RS17250	COG0243	molybdopterin cofactor binding
J415_RS17250	COG3383	formate dehydrogenase (NAD+) activity
J415_RS17255	COG0243	molybdopterin cofactor binding
J415_RS17255	COG3383	formate dehydrogenase (NAD+) activity
J415_RS17265	COG0697	spore germination
J415_RS17285	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
J415_RS17290	COG1140	nitrate reductase beta subunit
J415_RS17295	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
J415_RS17300	COG2181	nitrate reductase activity
J415_RS17305	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J415_RS17310	COG1178	ABC-type Fe3 transport system permease component
J415_RS17315	COG1840	ABC-type Fe3 transport system, periplasmic component
J415_RS17320	COG3842	ATPase activity
J415_RS17325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J415_RS17330	COG4977	sequence-specific DNA binding
J415_RS17365	COG0625	glutathione transferase activity
J415_RS17370	COG1609	Transcriptional regulator
J415_RS17380	COG2271	Major facilitator Superfamily
J415_RS17390	COG1126	abc transporter atp-binding protein
J415_RS17405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS17410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J415_RS17415	COG1473	amidohydrolase
J415_RS17420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J415_RS17445	COG4772	TonB-dependent receptor
J415_RS17450	COG3691	Protein conserved in bacteria
J415_RS17460	COG2130	NADP-dependent
J415_RS17475	COG1247	-acetyltransferase
J415_RS17480	COG3238	Protein conserved in bacteria
J415_RS17490	COG0747	negative chemotaxis
J415_RS17495	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS17500	COG4677	pectinesterase activity
J415_RS17505	COG0596	Alpha beta hydrolase
J415_RS17515	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS17520	COG1177	transmembrane transport
J415_RS17525	COG1176	ABC-type spermidine putrescine transport system, permease component I
J415_RS17530	COG3842	ATPase activity
J415_RS17535	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J415_RS17545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J415_RS17550	COG1271	oxidase subunit
J415_RS17555	COG1294	oxidase, subunit
J415_RS17565	COG0826	peptidase U32
J415_RS17570	COG1396	sequence-specific DNA binding
J415_RS17575	COG3135	benzoate transporter
J415_RS17580	COG2207	Transcriptional regulator
J415_RS17585	COG0697	spore germination
J415_RS17595	COG0747	negative chemotaxis
J415_RS17600	COG2195	Cleaves the N-terminal amino acid of tripeptides
J415_RS17605	COG0500	methyltransferase
J415_RS17610	COG1275	C4-dicarboxylate transporter malic acid transport protein
J415_RS17615	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J415_RS17620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J415_RS17630	COG2272	Belongs to the type-B carboxylesterase lipase family
J415_RS17635	COG5383	Protein conserved in bacteria
J415_RS17640	COG3485	protocatechuate 3,4-dioxygenase
J415_RS17645	COG3485	protocatechuate 3,4-dioxygenase
J415_RS17650	COG0583	DNA-binding transcription factor activity
J415_RS17680	COG3038	cytochrome b561
J415_RS17700	COG3706	GGDEF domain
J415_RS17705	COG0583	DNA-binding transcription factor activity
J415_RS17710	COG0456	acetyltransferase
J415_RS17715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J415_RS17720	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS17725	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J415_RS17730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J415_RS17750	COG1538	Outer membrane efflux protein
J415_RS17755	COG4122	O-methyltransferase activity
J415_RS17760	COG1643	Atp-dependent helicase
J415_RS17775	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J415_RS17780	COG3327	negative regulation of DNA-templated transcription, initiation
J415_RS17785	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
J415_RS17795	COG2050	protein possibly involved in aromatic compounds catabolism
J415_RS17800	COG1250	3-hydroxyacyl-CoA dehydrogenase
J415_RS17805	COG1024	Enoyl-CoA hydratase
J415_RS17810	COG1024	Enoyl-CoA hydratase
J415_RS17815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J415_RS17820	COG2151	metal-sulfur cluster biosynthetic enzyme
J415_RS17825	COG3396	Phenylacetate-CoA oxygenase
J415_RS17830	COG3460	Phenylacetate-CoA oxygenase
J415_RS17835	COG3396	Phenylacetate-CoA oxygenase
J415_RS17840	COG2030	dehydratase
J415_RS17840	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS17865	COG0583	DNA-binding transcription factor activity
J415_RS17885	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J415_RS17890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J415_RS17900	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS17905	COG2378	regulation of single-species biofilm formation
J415_RS17910	COG0406	alpha-ribazole phosphatase activity
J415_RS17925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J415_RS17930	COG2207	Transcriptional regulator
J415_RS17930	COG3708	Transcriptional regulator
J415_RS17935	COG2207	Transcriptional regulator
J415_RS17950	COG1566	PFAM secretion protein HlyD family protein
J415_RS17975	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J415_RS18010	COG0583	DNA-binding transcription factor activity
J415_RS18015	COG1126	abc transporter atp-binding protein
J415_RS18020	COG5285	phytanoyl-CoA dioxygenase
J415_RS18035	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS18040	COG2207	Transcriptional regulator
J415_RS18045	COG3784	Protein of unknown function (DUF1318)
J415_RS18055	COG2911	Protein conserved in bacteria
J415_RS18060	COG0586	Pfam SNARE associated Golgi protein
J415_RS18065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J415_RS18075	COG3042	response to heat
J415_RS18150	COG1013	pyruvate-flavodoxin oxidoreductase activity
J415_RS18150	COG0674	pyruvate-flavodoxin oxidoreductase activity
J415_RS18150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J415_RS18150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J415_RS18155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J415_RS18165	COG0589	response to stress
J415_RS18190	COG0513	Belongs to the DEAD box helicase family
J415_RS18210	COG0673	inositol 2-dehydrogenase activity
J415_RS18215	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J415_RS18220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J415_RS18240	COG3477	response to acidic pH
J415_RS18245	COG2885	chlorophyll binding
J415_RS18245	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
J415_RS18265	COG0300	oxidoreductase activity
J415_RS18275	COG0583	DNA-binding transcription factor activity
J415_RS18300	COG0789	Transcriptional regulator
J415_RS18310	COG0300	oxidoreductase activity
J415_RS18325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J415_RS18335	COG3272	Protein of unknown function (DUF1722)
J415_RS18340	COG4580	involved in the transport of maltose and maltodextrins
J415_RS18345	COG2211	Major facilitator Superfamily
J415_RS18350	COG3507	Belongs to the glycosyl hydrolase 43 family
J415_RS18435	COG0693	protein deglycase activity
J415_RS18445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J415_RS18460	COG2515	1-aminocyclopropane-1-carboxylate deaminase
J415_RS18465	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J415_RS18475	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J415_RS18485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J415_RS18490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J415_RS18510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J415_RS18515	COG1045	serine acetyltransferase
J415_RS18525	COG0765	amino acid transport
J415_RS18530	COG1126	abc transporter atp-binding protein
J415_RS18535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS18540	COG1605	Chorismate mutase
J415_RS18545	COG2188	Transcriptional regulator
J415_RS18560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J415_RS18575	COG2814	Major facilitator Superfamily
J415_RS18580	COG1464	Belongs to the NlpA lipoprotein family
J415_RS18585	COG2011	ABC-type metal ion transport system permease component
J415_RS18600	COG4166	transmembrane transport
J415_RS18605	COG2866	Carboxypeptidase
J415_RS18610	COG4948	Mandelate Racemase Muconate Lactonizing
J415_RS18615	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J415_RS18620	COG3180	Ammonia monooxygenase
J415_RS18635	COG3106	COG3106 Predicted ATPase
J415_RS18640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J415_RS18650	COG1983	PspC domain protein
J415_RS18660	COG1842	Phage shock protein A
J415_RS18665	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J415_RS18675	COG1473	amidohydrolase
J415_RS18690	COG4166	transmembrane transport
J415_RS18700	COG4171	peptide transport system, permease
J415_RS18710	COG4172	Belongs to the ABC transporter superfamily
J415_RS18715	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J415_RS18720	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J415_RS18720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J415_RS18735	COG1349	DNA-binding transcription factor activity
J415_RS18745	COG0023	Translation Initiation Factor
J415_RS18755	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J415_RS18760	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J415_RS18765	COG0671	phosphoesterase, PA-phosphatase related
J415_RS18775	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J415_RS18795	COG0616	signal peptide processing
J415_RS18800	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS18810	COG2207	Transcriptional regulator
J415_RS18815	COG1472	Belongs to the glycosyl hydrolase 3 family
J415_RS18825	COG1187	pseudouridine synthase activity
J415_RS18830	COG0009	L-threonylcarbamoyladenylate synthase
J415_RS18840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J415_RS18845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J415_RS18845	COG0512	Glutamine amidotransferase of anthranilate synthase
J415_RS18850	COG0134	indole-3-glycerol-phosphate synthase activity
J415_RS18850	COG0135	phosphoribosylanthranilate isomerase activity
J415_RS18875	COG0583	DNA-binding transcription factor activity
J415_RS18900	COG3047	cAMP biosynthetic process
J415_RS18915	COG0038	chloride channel
J415_RS18935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J415_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS18945	COG1988	membrane-bound metal-dependent
J415_RS18950	COG1823	symporter activity
J415_RS18970	COG1486	melibiose metabolic process
J415_RS18975	COG1917	Cupin 2, conserved barrel domain protein
J415_RS18975	COG2169	Transcriptional regulator
J415_RS18980	COG1447	Phosphotransferase system cellobiose-specific component IIA
J415_RS18985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J415_RS18990	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J415_RS18995	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J415_RS19005	COG0322	excinuclease ABC activity
J415_RS19015	COG1704	LemA family
J415_RS19020	COG3678	ATP-independent chaperone mediated protein folding
J415_RS19040	COG3138	arginine N-succinyltransferase
J415_RS19050	COG0708	Exodeoxyribonuclease III
J415_RS19055	COG0398	Pfam SNARE associated Golgi protein
J415_RS19060	COG0398	Pfam SNARE associated Golgi protein
J415_RS19065	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J415_RS19070	COG4134	Bacterial extracellular solute-binding protein
J415_RS19075	COG4135	transport system, permease component
J415_RS19080	COG4136	ATPase activity
J415_RS19085	COG2897	thiosulfate sulfurtransferase activity
J415_RS19090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J415_RS19095	COG0494	nUDIX hydrolase
J415_RS19105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J415_RS19110	COG0709	Synthesizes selenophosphate from selenide and ATP
J415_RS19120	COG0778	Nitroreductase
J415_RS19125	COG0616	signal peptide processing
J415_RS19130	COG0252	asparaginase activity
J415_RS19135	COG1335	isochorismatase
J415_RS19140	COG2814	Major facilitator Superfamily
J415_RS19145	COG1349	DNA-binding transcription factor activity
J415_RS19150	COG0667	Aldo Keto reductase
J415_RS19155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J415_RS19160	COG0191	fructose-bisphosphate aldolase activity
J415_RS19165	COG1063	alcohol dehydrogenase
J415_RS19170	COG2271	Major facilitator Superfamily
J415_RS19175	COG1063	alcohol dehydrogenase
J415_RS19190	COG3139	Protein of unknown function (DUF1315)
J415_RS19210	COG0656	L-ascorbic acid biosynthetic process
J415_RS19215	COG3713	MltA-interacting MipA family protein
J415_RS19220	COG2766	serine protein kinase
J415_RS19230	COG0859	PFAM glycosyl transferase family 9
J415_RS19240	COG2199	diguanylate cyclase activity
J415_RS19245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J415_RS19255	COG2207	Transcriptional regulator
J415_RS19265	COG0504	CTP synthase activity
J415_RS19270	COG1683	Conserved Protein
J415_RS19280	COG3042	response to heat
J415_RS19375	COG4695	Portal protein
J415_RS19380	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
J415_RS19400	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J415_RS19435	COG4974	Belongs to the 'phage' integrase family
J415_RS19440	COG2203	Gaf domain
J415_RS19440	COG2199	diguanylate cyclase activity
J415_RS19450	COG3182	Iron-regulated membrane protein
J415_RS19460	COG1560	Kdo2-lipid A biosynthetic process
J415_RS19465	COG2226	methyltransferase
J415_RS19470	COG1595	DNA-templated transcription, initiation
J415_RS19475	COG3712	iron ion homeostasis
J415_RS19480	COG4772	TonB-dependent receptor
J415_RS19485	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J415_RS19490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J415_RS19495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J415_RS19500	COG1120	ATPase activity
J415_RS19510	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J415_RS19515	COG3706	GGDEF domain
J415_RS19520	COG0538	isocitrate dehydrogenase activity
J415_RS19525	COG1187	pseudouridine synthase activity
J415_RS19545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J415_RS19550	COG2814	Major facilitator Superfamily
J415_RS19560	COG0745	RESPONSE REGULATOR receiver
J415_RS19565	COG2205	protein histidine kinase activity
J415_RS19570	COG2850	peptidyl-arginine hydroxylation
J415_RS19590	COG1177	transmembrane transport
J415_RS19605	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J415_RS19610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J415_RS19615	COG0698	ribose 5-phosphate isomerase
J415_RS19630	COG3395	kinase activity
J415_RS19645	COG2390	Transcriptional regulator
J415_RS19650	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J415_RS19660	COG4591	ABC-type transport system involved in lipoprotein release permease component
J415_RS19665	COG1136	(ABC) transporter
J415_RS19670	COG4591	ABC-type transport system involved in lipoprotein release permease component
J415_RS19675	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J415_RS19680	COG1376	ErfK ybiS ycfS ynhG family protein
J415_RS19680	COG1388	LysM domain
J415_RS19690	COG1309	transcriptional regulator
J415_RS19700	COG3134	Outer membrane lipoprotein
J415_RS19705	COG1252	NADH dehydrogenase
J415_RS19730	COG5633	Lipoprotein
J415_RS19735	COG0537	adenosine 5'-monophosphoramidase activity
J415_RS19740	COG4773	Receptor
J415_RS19750	COG0084	hydrolase, TatD family'
J415_RS19755	COG0470	DNA polymerase III
J415_RS19765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J415_RS19770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J415_RS19775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J415_RS19790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J415_RS19810	COG1399	metal-binding, possibly nucleic acid-binding protein
J415_RS19815	COG0424	maF-like protein
J415_RS19830	COG1530	ribonuclease E activity
J415_RS19835	COG0583	DNA-binding transcription factor activity
J415_RS19840	COG2814	Major facilitator Superfamily
J415_RS19850	COG0673	inositol 2-dehydrogenase activity
J415_RS19860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J415_RS19870	COG2999	glutathione oxidoreductase activity
J415_RS19905	COG1560	Kdo2-lipid A biosynthetic process
J415_RS19920	COG5645	(Lipo)protein
J415_RS19960	COG3381	protein complex oligomerization
J415_RS19980	COG0583	DNA-binding transcription factor activity
J415_RS19990	COG1335	isochorismatase
J415_RS20010	COG5002	protein histidine kinase activity
J415_RS20010	COG3850	Histidine kinase
J415_RS20025	COG1702	phosphate starvation-inducible protein PhoH
J415_RS20035	COG2822	iron ion transport
J415_RS20045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J415_RS20055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J415_RS20070	COG1309	transcriptional regulator
J415_RS20105	COG2233	PERMEase
J415_RS20110	COG3729	General stress protein
J415_RS20140	COG0531	amino acid
J415_RS20145	COG0174	glutamine synthetase
J415_RS20150	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J415_RS20155	COG1396	sequence-specific DNA binding
J415_RS20155	COG1917	Cupin 2, conserved barrel domain protein
J415_RS20160	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS20165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J415_RS20170	COG0583	DNA-binding transcription factor activity
J415_RS20175	COG0473	3-isopropylmalate dehydrogenase activity
J415_RS20180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J415_RS20180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS20180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS20185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS20190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS20195	COG1882	Formate acetyltransferase
J415_RS20200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J415_RS20205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J415_RS20215	COG2207	Transcriptional regulator
J415_RS20220	COG3706	GGDEF domain
J415_RS20230	COG1605	Chorismate mutase
J415_RS20230	COG0287	Prephenate dehydrogenase
J415_RS20265	COG0765	amino acid transport
J415_RS20320	COG1953	Uracil, thiamine, allantoin
J415_RS20330	COG2351	hydroxyisourate hydrolase activity
J415_RS20340	COG2233	PERMEase
J415_RS20415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J415_RS20425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J415_RS20440	COG5002	protein histidine kinase activity
J415_RS20445	COG0745	RESPONSE REGULATOR receiver
J415_RS20455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J415_RS20465	COG1278	Cold shock
J415_RS20470	COG1278	Cold shock
J415_RS20475	COG0471	metal ion transport
J415_RS20490	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
J415_RS20510	COG3052	prosthetic group binding
J415_RS20515	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
J415_RS20520	COG0179	Fumarylacetoacetate (FAA) hydrolase
J415_RS20525	COG2814	Major facilitator Superfamily
J415_RS20530	COG2828	Protein conserved in bacteria
J415_RS20535	COG0583	DNA-binding transcription factor activity
J415_RS20555	COG0765	amino acid transport
J415_RS20560	COG1126	abc transporter atp-binding protein
J415_RS20595	COG0814	amino acid
J415_RS20615	COG0604	alcohol dehydrogenase
J415_RS20620	COG0300	oxidoreductase activity
J415_RS20635	COG1486	melibiose metabolic process
J415_RS20640	COG2207	Transcriptional regulator
J415_RS20655	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS20665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS20670	COG0765	amino acid transport
J415_RS20675	COG1126	abc transporter atp-binding protein
J415_RS20680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J415_RS20690	COG0006	proline dipeptidase activity
J415_RS20695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J415_RS20700	COG0504	CTP synthase activity
J415_RS20705	COG0436	Aminotransferase
J415_RS20710	COG2188	Transcriptional regulator
J415_RS20720	COG3715	PTS system
J415_RS20725	COG3716	PTS system mannose fructose sorbose family IID component
J415_RS20730	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS20735	COG4821	SIS domain
J415_RS20745	COG4821	SIS domain
J415_RS20770	COG0670	Belongs to the BI1 family
J415_RS20790	COG1881	PFAM PEBP family protein
J415_RS20815	COG0438	transferase activity, transferring glycosyl groups
J415_RS20820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J415_RS20825	COG2274	protein secretion by the type I secretion system
J415_RS20845	COG1832	CoA-binding protein
J415_RS20860	COG3304	Inner membrane component domain
J415_RS20865	COG1289	transmembrane transporter activity
J415_RS20870	COG3070	regulator of competence-specific genes
J415_RS20890	COG1067	ATP-dependent peptidase activity
J415_RS20905	COG3009	Protein conserved in bacteria
J415_RS20910	COG3008	intermembrane lipid transfer
J415_RS20910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J415_RS20915	COG2995	paraquat-inducible protein a
J415_RS20920	COG0488	(ABC) transporter
J415_RS20930	COG0633	Ferredoxin
J415_RS20930	COG3217	Mosc domain protein beta barrel domain protein
J415_RS20945	COG0431	NADPH-dependent FMN reductase
J415_RS20950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J415_RS20955	COG1116	anion transmembrane transporter activity
J415_RS20960	COG0308	aminopeptidase N
J415_RS20975	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J415_RS20980	COG1448	Aminotransferase
J415_RS20985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J415_RS20990	COG3108	Peptidase M15
J415_RS21000	COG2989	Protein conserved in bacteria
J415_RS21020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J415_RS21025	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J415_RS21030	COG3173	Aminoglycoside phosphotransferase
J415_RS21045	COG3214	Protein conserved in bacteria
J415_RS21055	COG1132	(ABC) transporter
J415_RS21070	COG0539	negative regulation of cytoplasmic translation
J415_RS21090	COG2323	membrane
J415_RS21095	COG1944	ATP diphosphatase activity
J415_RS21100	COG2116	formate transmembrane transporter activity
J415_RS21105	COG1882	Formate acetyltransferase
J415_RS21110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J415_RS21130	COG3959	Transketolase, thiamine diphosphate binding domain
J415_RS21135	COG3958	Transketolase
J415_RS21140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS21145	COG0477	Major facilitator Superfamily
J415_RS21150	COG3302	dmso reductase anchor subunit
J415_RS21155	COG0437	4 iron, 4 sulfur cluster binding
J415_RS21160	COG0243	molybdopterin cofactor binding
J415_RS21170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J415_RS21190	COG0492	ferredoxin-NADP+ reductase activity
J415_RS21195	COG4988	ABC transporter
J415_RS21200	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J415_RS21210	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J415_RS21235	COG1203	CRISPR-associated helicase, Cas3
J415_RS21240	COG0542	response to heat
J415_RS21250	COG1278	Cold shock
J415_RS21260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J415_RS21265	COG3593	DNA synthesis involved in DNA repair
J415_RS21270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J415_RS21275	COG2431	L-lysine efflux transmembrane transporter activity
J415_RS21285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J415_RS21290	COG0028	Belongs to the TPP enzyme family
J415_RS21295	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
J415_RS21300	COG0702	epimerase
J415_RS21305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J415_RS21310	COG3023	N-Acetylmuramoyl-L-alanine amidase
J415_RS21315	COG0393	Putative heavy-metal-binding
J415_RS21325	COG1126	abc transporter atp-binding protein
J415_RS21330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS21335	COG4215	(ABC) transporter
J415_RS21340	COG4160	amino acid transport
J415_RS21345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS21350	COG5002	protein histidine kinase activity
J415_RS21355	COG0745	RESPONSE REGULATOR receiver
J415_RS21370	COG1177	transmembrane transport
J415_RS21375	COG1176	ABC-type spermidine putrescine transport system, permease component I
J415_RS21380	COG3842	ATPase activity
J415_RS21385	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J415_RS21400	COG0778	Nitroreductase
J415_RS21440	COG3226	Transcriptional regulator
J415_RS21445	COG0738	Major facilitator superfamily
J415_RS21450	COG0561	phosphatase activity
J415_RS21455	COG2814	Major facilitator Superfamily
J415_RS21460	COG0671	phosphoesterase, PA-phosphatase related
J415_RS21465	COG1349	DNA-binding transcription factor activity
J415_RS21470	COG1686	Belongs to the peptidase S11 family
J415_RS21480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J415_RS21555	COG3179	chitinase
J415_RS21575	COG0484	heat shock protein binding
J415_RS21640	COG1846	Transcriptional regulator
J415_RS21650	COG1396	sequence-specific DNA binding
J415_RS21690	COG0582	viral genome integration into host DNA
J415_RS21695	COG0625	glutathione transferase activity
J415_RS21700	COG2133	pyrroloquinoline quinone binding
J415_RS21735	COG0747	negative chemotaxis
J415_RS21745	COG1446	asparaginase
J415_RS21750	COG0303	'Molybdopterin
J415_RS21755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J415_RS21760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J415_RS21765	COG1882	Formate acetyltransferase
J415_RS21770	COG0561	phosphatase activity
J415_RS21780	COG1609	Transcriptional regulator
J415_RS21785	COG2271	Major facilitator Superfamily
J415_RS21795	COG0488	(ABC) transporter
J415_RS21805	COG1376	ErfK ybiS ycfS ynhG family protein
J415_RS21810	COG2188	Transcriptional regulator
J415_RS21815	COG2723	6-phospho-beta-galactosidase activity
J415_RS21820	COG0667	Aldo Keto reductase
J415_RS21825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J415_RS21840	COG2194	sulfuric ester hydrolase activity
J415_RS21845	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
J415_RS21860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS21865	COG0765	amino acid transport
J415_RS21870	COG1126	abc transporter atp-binding protein
J415_RS21875	COG0668	transmembrane transport
J415_RS21890	COG4774	siderophore transport
J415_RS21900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J415_RS21910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J415_RS21920	COG0513	Belongs to the DEAD box helicase family
J415_RS21925	COG3958	Transketolase
J415_RS21930	COG3959	Transketolase, thiamine diphosphate binding domain
J415_RS21935	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS21940	COG2271	Major facilitator Superfamily
J415_RS21945	COG0583	DNA-binding transcription factor activity
J415_RS21950	COG1309	transcriptional regulator
J415_RS21955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J415_RS21960	COG1131	(ABC) transporter
J415_RS21965	COG0842	Transport permease protein
J415_RS21970	COG0842	Transport permease protein
J415_RS21980	COG3568	Endonuclease Exonuclease Phosphatase
J415_RS21985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J415_RS21990	COG0392	lysyltransferase activity
J415_RS21995	COG0670	Belongs to the BI1 family
J415_RS22000	COG0314	molybdopterin synthase activity
J415_RS22005	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J415_RS22015	COG0521	Mo-molybdopterin cofactor biosynthetic process
J415_RS22035	COG0745	RESPONSE REGULATOR receiver
J415_RS22060	COG2226	methyltransferase
J415_RS22075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J415_RS22080	COG1881	PFAM PEBP family protein
J415_RS22110	COG4677	pectinesterase activity
J415_RS22125	COG0789	Transcriptional regulator
J415_RS22130	COG2200	EAL domain
J415_RS22165	COG0561	phosphatase activity
J415_RS22175	COG4149	molybdate abc transporter
J415_RS22180	COG0725	ABC transporter, periplasmic molybdate-binding protein
J415_RS22190	COG3585	molybdate ion transport
J415_RS22190	COG2005	Transcriptional regulator
J415_RS22195	COG1119	ATPase activity
J415_RS22200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J415_RS22205	COG1085	galactose-1-phosphate uridylyltransferase
J415_RS22215	COG2017	converts alpha-aldose to the beta-anomer
J415_RS22225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J415_RS22245	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J415_RS22265	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J415_RS22270	COG2885	chlorophyll binding
J415_RS22280	COG3064	Membrane
J415_RS22285	COG0848	biopolymer transport protein
J415_RS22290	COG0811	peptide transport
J415_RS22295	COG0824	Thioesterase
J415_RS22300	COG3790	cyd operon protein YbgE
J415_RS22305	COG1294	oxidase, subunit
J415_RS22310	COG1271	oxidase subunit
J415_RS22315	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J415_RS22325	COG4865	methylaspartate mutase activity
J415_RS22330	COG3799	methylaspartate ammonia-lyase activity
J415_RS22345	COG1301	dicarboxylic acid transport
J415_RS22355	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J415_RS22355	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J415_RS22370	COG0583	DNA-binding transcription factor activity
J415_RS22380	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J415_RS22390	COG0508	dehydrogenase complex catalyzes the overall conversion of
J415_RS22395	COG0567	Dehydrogenase, E1 component
J415_RS22400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J415_RS22405	COG1053	succinate dehydrogenase
J415_RS22410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J415_RS22420	COG0372	Belongs to the citrate synthase family
J415_RS22450	COG1984	allophanate hydrolase subunit 2
J415_RS22455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J415_RS22460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J415_RS22470	COG0415	Belongs to the DNA photolyase family
J415_RS22500	COG2205	protein histidine kinase activity
J415_RS22505	COG0745	RESPONSE REGULATOR receiver
J415_RS22515	COG3623	hexulose-6-phosphate isomerase
J415_RS22520	COG1070	Carbohydrate kinase
J415_RS22525	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS22530	COG1129	ABC transporter
J415_RS22535	COG1879	ABC-type sugar transport system periplasmic component
J415_RS22540	COG1063	alcohol dehydrogenase
J415_RS22555	COG0033	Phosphoglucomutase
J415_RS22565	COG0596	Alpha beta hydrolase
J415_RS22580	COG0735	belongs to the Fur family
J415_RS22585	COG0583	DNA-binding transcription factor activity
J415_RS22590	COG1053	succinate dehydrogenase
J415_RS22630	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J415_RS22635	COG1846	Transcriptional regulator
J415_RS22635	COG1940	carbohydrate kinase activity
J415_RS22640	COG0647	UMP catabolic process
J415_RS22650	COG0367	asparagine synthase
J415_RS22690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J415_RS22700	COG1702	phosphate starvation-inducible protein PhoH
J415_RS22705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J415_RS22710	COG4535	Mg2 and Co2 transporter CorC
J415_RS22725	COG0765	amino acid transport
J415_RS22730	COG0765	amino acid transport
J415_RS22735	COG1126	abc transporter atp-binding protein
J415_RS22740	COG2831	hemolysin activation secretion protein
J415_RS22750	COG2888	peptidyl-tyrosine sulfation
J415_RS22765	COG1466	dna polymerase III delta subunit
J415_RS22775	COG0406	alpha-ribazole phosphatase activity
J415_RS22780	COG0799	negative regulation of ribosome biogenesis
J415_RS22790	COG0768	penicillin binding
J415_RS22795	COG0772	Belongs to the SEDS family
J415_RS22800	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J415_RS22820	COG0583	DNA-binding transcription factor activity
J415_RS22830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J415_RS22835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J415_RS22855	COG3069	C4-dicarboxylate transmembrane transporter activity
J415_RS22860	COG3719	Belongs to the RNase T2 family
J415_RS22865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J415_RS22875	COG3634	alkyl hydroperoxide reductase activity
J415_RS22885	COG0583	DNA-binding transcription factor activity
J415_RS22890	COG3969	phosphoadenosine phosphosulfate
J415_RS22895	COG1475	DNA binding
J415_RS22900	COG0436	Aminotransferase
J415_RS22905	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
J415_RS22910	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
J415_RS22925	COG1129	ABC transporter
J415_RS22930	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS22935	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS22945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J415_RS22960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J415_RS22970	COG0402	S-adenosylhomocysteine deaminase activity
J415_RS22980	COG0483	inositol monophosphate 1-phosphatase activity
J415_RS23015	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS23020	COG1129	ABC transporter
J415_RS23025	COG0371	Dehydrogenase
J415_RS23035	COG2879	small protein
J415_RS23040	COG1966	Carbon starvation protein
J415_RS23050	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS23055	COG3433	isochorismatase activity
J415_RS23055	COG1535	isochorismatase
J415_RS23060	COG1021	2,3-dihydroxybenzoate-AMP ligase
J415_RS23065	COG1169	isochorismate synthase
J415_RS23070	COG4592	Periplasmic binding protein
J415_RS23085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J415_RS23090	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J415_RS23095	COG1120	ATPase activity
J415_RS23100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J415_RS23100	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J415_RS23105	COG3251	PFAM MbtH domain protein
J415_RS23110	COG2382	esterase
J415_RS23115	COG4771	TonB-dependent receptor
J415_RS23125	COG3958	Transketolase
J415_RS23130	COG3959	Transketolase, thiamine diphosphate binding domain
J415_RS23135	COG2390	Transcriptional regulator
J415_RS23140	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J415_RS23145	COG1879	ABC-type sugar transport system periplasmic component
J415_RS23160	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS23170	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS23180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J415_RS23210	COG0601	transmembrane transport
J415_RS23215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J415_RS23220	COG0444	Belongs to the ABC transporter superfamily
J415_RS23225	COG4608	Belongs to the ABC transporter superfamily
J415_RS23230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J415_RS23235	COG4221	oxidoreductase activity
J415_RS23245	COG0765	amino acid transport
J415_RS23250	COG0765	amino acid transport
J415_RS23265	COG1280	lysine exporter protein (LysE YggA)
J415_RS23285	COG0154	amidase activity
J415_RS23290	COG0444	Belongs to the ABC transporter superfamily
J415_RS23295	COG4608	Belongs to the ABC transporter superfamily
J415_RS23300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J415_RS23350	COG4774	siderophore transport
J415_RS23370	COG2315	Protein conserved in bacteria
J415_RS23375	COG0778	Nitroreductase
J415_RS23450	COG3716	PTS system mannose fructose sorbose family IID component
J415_RS23460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS23465	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS23465	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS23470	COG3933	PFAM sigma-54 factor interaction domain-containing protein
J415_RS23470	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J415_RS23480	COG0477	Major facilitator Superfamily
J415_RS23485	COG0668	transmembrane transport
J415_RS23495	COG0494	nUDIX hydrolase
J415_RS23515	COG3188	usher protein
J415_RS23530	COG2771	luxR family
J415_RS23535	COG0583	DNA-binding transcription factor activity
J415_RS23540	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS23560	COG2211	Major facilitator Superfamily
J415_RS23565	COG1113	amino acid transport
J415_RS23575	COG0667	Aldo Keto reductase
J415_RS23580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS23585	COG1473	amidohydrolase
J415_RS23605	COG4139	cobalamin transport
J415_RS23610	COG1120	ATPase activity
J415_RS23640	COG3550	peptidyl-serine autophosphorylation
J415_RS23650	COG3711	transcriptional antiterminator
J415_RS23655	COG2723	6-phospho-beta-galactosidase activity
J415_RS23660	COG1263	PTS System
J415_RS23660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS23660	COG2190	(PTS) system
J415_RS23665	COG1172	Belongs to the binding-protein-dependent transport system permease family
J415_RS23670	COG1129	ABC transporter
J415_RS23685	COG0673	inositol 2-dehydrogenase activity
J415_RS23695	COG2367	Beta-lactamase
J415_RS23710	COG3104	oligopeptide transport
J415_RS23720	COG0531	amino acid
J415_RS23725	COG3710	Transcriptional regulator
J415_RS23735	COG0583	DNA-binding transcription factor activity
J415_RS23745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J415_RS23755	COG2808	Putative FMN-binding domain
J415_RS23770	COG2501	S4 domain
J415_RS23780	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J415_RS23790	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J415_RS23795	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J415_RS23815	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J415_RS23820	COG4181	ATPase activity
J415_RS23825	COG2755	lipolytic protein G-D-S-L family
J415_RS23830	COG0300	oxidoreductase activity
J415_RS23835	COG3118	belongs to the thioredoxin family
J415_RS23840	COG0390	transport system, permease component
J415_RS23845	COG4619	ABC transporter
J415_RS23850	COG0330	HflC and HflK could
J415_RS23855	COG1585	Membrane protein implicated in regulation of membrane protease activity
J415_RS23885	COG0811	peptide transport
J415_RS23905	COG3735	TraB family
J415_RS23955	COG2223	nitrite transmembrane transporter activity
J415_RS23960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J415_RS23960	COG4651	solute:proton antiporter activity
J415_RS23965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J415_RS24005	COG2832	Protein of unknown function (DUF454)
J415_RS24010	COG3923	Primosomal replication protein n
J415_RS24020	COG3264	Mechanosensitive ion channel
J415_RS24020	COG1196	nuclear chromosome segregation
J415_RS24025	COG1309	transcriptional regulator
J415_RS24030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J415_RS24035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J415_RS24050	COG0110	maltose O-acetyltransferase activity
J415_RS24070	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J415_RS24090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J415_RS24090	COG1263	PTS System
J415_RS24095	COG1874	Beta-galactosidase
J415_RS24100	COG3867	Arabinogalactan endo-beta-1,4-galactanase
J415_RS24105	COG3833	ABC-type maltose transport systems, permease component
J415_RS24110	COG1175	transmembrane transport
J415_RS24115	COG2182	Extracellular solute-binding protein
J415_RS24125	COG4943	cyclic-guanylate-specific phosphodiesterase activity
J415_RS24140	COG5507	3-demethylubiquinone-9 3-methyltransferase
J415_RS24145	COG2364	Membrane
J415_RS24170	COG3695	enzyme binding
J415_RS24175	COG3126	Type III secretion system lipoprotein chaperone (YscW)
J415_RS24180	COG1946	Acyl-CoA thioesterase
J415_RS24185	COG0004	ammonium transporteR
J415_RS24190	COG0347	Belongs to the P(II) protein family
J415_RS24200	COG1132	(ABC) transporter
J415_RS24205	COG1132	(ABC) transporter
J415_RS24210	COG1522	sequence-specific DNA binding
J415_RS24225	COG4533	DNA binding
J415_RS24235	COG0824	Thioesterase
J415_RS24240	COG1555	photosystem II stabilization
J415_RS24245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J415_RS24250	COG0776	regulation of translation
J415_RS24255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J415_RS24275	COG0271	Belongs to the BolA IbaG family
J415_RS24280	COG3056	Lipoprotein
J415_RS24285	COG2223	nitrite transmembrane transporter activity
J415_RS24290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J415_RS24295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J415_RS24300	COG1845	cytochrome c oxidase, subunit III
J415_RS24305	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J415_RS24320	COG1414	Transcriptional regulator
J415_RS24330	COG1053	succinate dehydrogenase
J415_RS24360	COG2211	Major facilitator Superfamily
J415_RS24365	COG0673	inositol 2-dehydrogenase activity
J415_RS24370	COG2814	Major facilitator Superfamily
J415_RS24380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J415_RS24400	COG0142	geranyltranstransferase activity
J415_RS24410	COG0667	Aldo Keto reductase
J415_RS24415	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J415_RS24435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J415_RS24435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J415_RS24445	COG4238	major outer membrane lipoprotein
J415_RS24470	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J415_RS24480	COG1862	Preprotein translocase
J415_RS24495	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
J415_RS24500	COG0450	alkyl hydroperoxide reductase
J415_RS24515	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J415_RS24525	COG1335	isochorismatase
J415_RS24530	COG0583	DNA-binding transcription factor activity
J415_RS24535	COG0366	Alpha amylase catalytic
J415_RS24560	COG0420	3'-5' exonuclease activity
J415_RS24590	COG4126	flavin adenine dinucleotide binding
J415_RS24600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J415_RS24605	COG3416	Protein conserved in bacteria
J415_RS24615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J415_RS24625	COG1785	Belongs to the alkaline phosphatase family
J415_RS24635	COG1609	Transcriptional regulator
J415_RS24645	COG1028	Short-chain dehydrogenase reductase Sdr
J415_RS24680	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
J415_RS24690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J415_RS24695	COG0113	porphobilinogen synthase activity
J415_RS24705	COG2175	clavaminate synthase activity
J415_RS24710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J415_RS24715	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J415_RS24720	COG4521	taurine ABC transporter
J415_RS24735	COG2271	Major facilitator Superfamily
J415_RS24740	COG1840	ABC-type Fe3 transport system, periplasmic component
J415_RS24750	COG3842	ATPase activity
J415_RS24755	COG2040	homocysteine
J415_RS24760	COG0833	amino acid
J415_RS24765	COG5434	Belongs to the glycosyl hydrolase 28 family
J415_RS24775	COG4303	Ethanolamine ammonia lyase large subunit
J415_RS24780	COG4302	ethanolamine ammonia-lyase activity
J415_RS24815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J415_RS24820	COG1126	abc transporter atp-binding protein
J415_RS24825	COG0765	amino acid transport
J415_RS24830	COG0765	amino acid transport
J415_RS24845	COG3188	usher protein
J415_RS24870	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
J415_RS24880	COG3639	organic phosphonate transmembrane transporter activity
J415_RS24900	COG3118	belongs to the thioredoxin family
J415_RS24915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J415_RS24920	COG0583	DNA-binding transcription factor activity
J415_RS24925	COG0791	NLP P60 protein
J415_RS24930	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J415_RS24935	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J415_RS24940	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J415_RS24950	COG0582	viral genome integration into host DNA
J415_RS24985	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J415_RS25015	COG0431	NADPH-dependent FMN reductase
J415_RS25030	COG3596	GTP binding
J415_RS25045	COG2003	Belongs to the UPF0758 family
J415_RS25070	COG2171	N-acyltransferase activity
J415_RS25075	COG1309	transcriptional regulator
J415_RS25105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J415_RS25135	COG2986	histidine ammonia-lyase
J415_RS25145	COG2188	Transcriptional regulator
J415_RS25150	COG0402	S-adenosylhomocysteine deaminase activity
J415_RS25155	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J415_RS25165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J415_RS25175	COG0477	Major facilitator Superfamily
J415_RS25195	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J415_RS25200	COG3153	acetyltransferase
J415_RS25215	COG0246	Mannitol dehydrogenase
J415_RS25220	COG2186	Transcriptional regulator
J415_RS25240	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS25255	COG1596	polysaccharide export
J415_RS25275	COG0463	Glycosyl transferase, family 2
J415_RS25285	COG0297	glycogen (starch) synthase activity
J415_RS25285	COG0438	transferase activity, transferring glycosyl groups
J415_RS25300	COG1045	serine acetyltransferase
J415_RS25320	COG2195	Cleaves the N-terminal amino acid of tripeptides
J415_RS25325	COG0454	-acetyltransferase
J415_RS25340	COG2991	Protein conserved in bacteria
J415_RS25355	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J415_RS25360	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J415_RS25375	COG3034	peptidoglycan biosynthetic process
J415_RS25380	COG0121	glutamine amidotransferase
J415_RS25395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J415_RS25415	COG2226	methyltransferase
J415_RS25425	COG0741	lytic transglycosylase activity
J415_RS25425	COG1388	LysM domain
J415_RS25430	COG2226	methyltransferase
J415_RS25440	COG2814	Major facilitator Superfamily
J415_RS25445	COG0583	DNA-binding transcription factor activity
J415_RS25485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J415_RS25495	COG2011	ABC-type metal ion transport system permease component
J415_RS25500	COG1464	Belongs to the NlpA lipoprotein family
J415_RS25510	COG1720	tRNA m6t6A37 methyltransferase activity
J415_RS25520	COG0791	NLP P60 protein
J415_RS25525	COG3015	lipoprotein NlpE involved in copper resistance
J415_RS25530	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
J415_RS25535	COG4681	YaeQ
J415_RS25545	COG4568	rho-dependent transcription termination
J415_RS25555	COG0346	lactoylglutathione lyase activity
J415_RS25560	COG1982	Orn Lys Arg decarboxylase major
J415_RS25600	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J415_RS25605	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
J415_RS25615	COG0750	zinc metalloprotease
J415_RS25620	COG0575	Belongs to the CDS family
J415_RS25645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J415_RS25655	COG0024	Methionine aminopeptidase
J415_RS25665	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J415_RS25685	COG3835	regulator
J415_RS25690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J415_RS25710	COG2860	membrane
J415_RS25730	COG5464	transposase or invertase
J415_RS25735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J415_RS25740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J415_RS25745	COG1120	ATPase activity
J415_RS25750	COG4774	siderophore transport
J415_RS25755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J415_RS25845	COG1643	Atp-dependent helicase
J415_RS25850	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J415_RS25870	COG0617	tRNA 3'-terminal CCA addition
J415_RS25875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J415_RS25895	COG3539	Fimbrial protein
J415_RS25900	COG3121	Chaperone
J415_RS25905	COG3188	usher protein
J415_RS25930	COG0726	polysaccharide deacetylase
J415_RS25935	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J415_RS25940	COG0842	Transport permease protein
J415_RS25945	COG1131	(ABC) transporter
J415_RS25950	COG0288	reversible hydration of carbon dioxide
J415_RS25960	COG4993	Dehydrogenase
J415_RS25965	COG2132	Multicopper oxidase
J415_RS25980	COG0545	Peptidyl-prolyl cis-trans isomerase
J415_RS25995	COG1349	DNA-binding transcription factor activity
J415_RS26025	COG3064	Membrane
J415_RS26040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J415_RS26045	COG0508	dehydrogenase complex catalyzes the overall conversion of
J415_RS26050	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J415_RS26055	COG2186	Transcriptional regulator
J415_RS26060	COG1113	amino acid transport
J415_RS26065	COG2211	Major facilitator Superfamily
J415_RS26070	COG3940	Belongs to the glycosyl hydrolase 43 family
J415_RS26075	COG3725	Membrane protein required for beta-lactamase induction
J415_RS26090	COG4969	Belongs to the N-Me-Phe pilin family
J415_RS26095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J415_RS26100	COG1459	type II secretion system
J415_RS26120	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J415_RS26125	COG0494	nUDIX hydrolase
J415_RS26145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J415_RS26175	COG0772	Belongs to the SEDS family
J415_RS26190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J415_RS26200	COG0768	penicillin binding
J415_RS26220	COG1609	Transcriptional regulator
J415_RS26230	COG0028	Belongs to the TPP enzyme family
J415_RS26240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J415_RS26265	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J415_RS26270	COG0738	Major facilitator superfamily
J415_RS26280	COG0583	DNA-binding transcription factor activity
J415_RS26285	COG2271	Major facilitator Superfamily
J415_RS26290	COG2814	Major facilitator Superfamily
J415_RS26305	COG1178	ABC-type Fe3 transport system permease component
J415_RS26315	COG0586	Pfam SNARE associated Golgi protein
J415_RS26335	COG0235	Class ii aldolase
J415_RS26340	COG0417	DNA replication proofreading
J415_RS26350	COG0564	pseudouridine synthase activity
J415_RS26360	COG3493	citrate carrier protein
J415_RS26375	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J415_RS26390	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J415_RS26480	COG5016	pyruvate
J415_RS26480	COG0511	ligase activity, forming carbon-carbon bonds
J415_RS26500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J415_RS26510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J415_RS26515	COG0471	metal ion transport
J415_RS26520	COG0471	metal ion transport
J415_RS26525	COG2828	Protein conserved in bacteria
J415_RS26530	COG0583	DNA-binding transcription factor activity
J415_RS26545	COG1047	Peptidyl-prolyl cis-trans
J415_RS26560	COG0196	riboflavin kinase activity
J415_RS26570	COG0583	DNA-binding transcription factor activity
J415_RS26630	COG4735	regulation of single-species biofilm formation
J415_RS26635	COG1584	GPR1 FUN34 yaaH family protein
J415_RS26645	COG0521	Mo-molybdopterin cofactor biosynthetic process
J415_RS26650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J415_RS26655	COG1115	amino acid carrier protein
J415_RS26665	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J415_RS26675	COG0527	aspartate kinase activity
J415_RS26675	COG0460	homoserine dehydrogenase
J415_RS26680	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J415_RS26685	COG0745	RESPONSE REGULATOR receiver
J415_RS26690	COG4452	Inner membrane protein CreD
J415_RS26695	COG2205	protein histidine kinase activity
J415_RS26700	COG0745	RESPONSE REGULATOR receiver
J415_RS26705	COG3045	CreA protein
J415_RS26710	COG3708	Transcriptional regulator
J415_RS26710	COG2207	Transcriptional regulator
J415_RS26730	COG0741	lytic transglycosylase activity
J415_RS26735	COG0488	(ABC) transporter
J415_RS26750	COG0560	Phosphoserine phosphatase
J415_RS26755	COG3726	membrane protein affecting hemolysin expression
J415_RS26765	COG0813	purine-nucleoside phosphorylase activity
J415_RS26785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J415_RS26790	COG0084	hydrolase, TatD family'
J415_RS26795	COG4667	esterase of the alpha-beta hydrolase superfamily
J415_RS26800	COG2823	Periplasmic or secreted lipoprotein
J415_RS26810	COG1011	Hydrolase
J415_RS26815	COG0456	acetyltransferase
J415_RS26820	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
J415_RS26850	COG3706	GGDEF domain
J415_RS26855	COG4114	ferric iron reductase
J415_RS26860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J415_RS26865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J415_RS26870	COG2197	response regulator
J415_RS26875	COG2197	response regulator
J415_RS26880	COG2207	Transcriptional regulator
J415_RS26890	COG2966	Psort location CytoplasmicMembrane, score
J415_RS26905	COG1484	DNA-dependent DNA replication
J415_RS26920	COG5464	transposase or invertase
J415_RS26925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J415_RS26930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J415_RS26935	COG3716	PTS system mannose fructose sorbose family IID component
J415_RS26940	COG3715	PTS system
J415_RS26955	COG3933	PFAM sigma-54 factor interaction domain-containing protein
J415_RS26955	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J415_RS26965	COG1063	alcohol dehydrogenase
J415_RS26970	COG1802	Transcriptional regulator
J415_RS26975	COG2271	Major facilitator Superfamily
J415_RS26980	COG0456	acetyltransferase
J415_RS26990	COG1737	Transcriptional regulator
J415_RS26995	COG0800	Aldolase
J415_RS27000	COG3734	2-keto-3-deoxy-galactonokinase
J415_RS27005	COG4145	pantothenate transmembrane transporter activity
J415_RS27015	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
J415_RS27025	COG1846	Transcriptional regulator
J415_RS27030	COG0179	Fumarylacetoacetate (FAA) hydrolase
J415_RS27040	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS27045	COG3384	dioxygenase
J415_RS27055	COG3971	2-oxopent-4-enoate hydratase activity
J415_RS27075	COG2368	4-hydroxyphenylacetate
J415_RS27080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J415_RS27085	COG1966	Carbon starvation protein
J415_RS27090	COG2879	small protein
J415_RS27095	COG0523	cobalamin synthesis protein
J415_RS27110	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS27115	COG5464	transposase or invertase
J415_RS27125	COG1280	lysine exporter protein (LysE YggA)
J415_RS27130	COG2733	membrane
J415_RS27135	COG2814	Major facilitator Superfamily
J415_RS27140	COG1475	DNA binding
J415_RS27145	COG3969	phosphoadenosine phosphosulfate
J415_RS27155	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
J415_RS27160	COG1924	4 iron, 4 sulfur cluster binding
J415_RS27170	COG1473	amidohydrolase
J415_RS27175	COG0700	Nucleoside recognition
J415_RS27180	COG3366	ferrous iron transmembrane transporter activity
J415_RS27185	COG0583	DNA-binding transcription factor activity
J415_RS27195	COG1566	PFAM secretion protein HlyD family protein
J415_RS27205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J415_RS27240	COG0531	amino acid
J415_RS27300	COG1454	alcohol dehydrogenase
J415_RS27300	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS27310	COG1454	alcohol dehydrogenase
J415_RS27310	COG1012	belongs to the aldehyde dehydrogenase family
J415_RS27315	COG1882	Formate acetyltransferase
J415_RS27320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J415_RS27330	COG4869	propanediol catabolic process
J415_RS27360	COG0814	amino acid
J415_RS27370	COG3706	GGDEF domain
J415_RS27375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J415_RS27380	COG1129	ABC transporter
J415_RS27380	COG0842	Transport permease protein
J415_RS27385	COG0842	Transport permease protein
J415_RS27470	COG1203	CRISPR-associated helicase, Cas3