locus-tag	class	description
KONIH1_RS00020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KONIH1_RS00030	COG3852	Histidine kinase
KONIH1_RS00045	COG1011	Hydrolase
KONIH1_RS00055	COG1490	D-aminoacyl-tRNA deacylase activity
KONIH1_RS00060	COG0456	acetyltransferase
KONIH1_RS00065	COG0657	acetylesterase activity
KONIH1_RS00075	COG2864	formate dehydrogenase
KONIH1_RS00080	COG0437	4 iron, 4 sulfur cluster binding
KONIH1_RS00085	COG0243	molybdopterin cofactor binding
KONIH1_RS00085	COG3383	formate dehydrogenase (NAD+) activity
KONIH1_RS00090	COG3383	formate dehydrogenase (NAD+) activity
KONIH1_RS00090	COG0243	molybdopterin cofactor binding
KONIH1_RS00115	COG3716	PTS system mannose fructose sorbose family IID component
KONIH1_RS00120	COG3715	PTS system
KONIH1_RS00130	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KONIH1_RS00145	COG0205	6-phosphofructokinase activity
KONIH1_RS00185	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KONIH1_RS00230	COG2211	Major facilitator Superfamily
KONIH1_RS00235	COG0110	maltose O-acetyltransferase activity
KONIH1_RS00250	COG3539	Fimbrial protein
KONIH1_RS00260	COG3121	Chaperone
KONIH1_RS00265	COG3188	usher protein
KONIH1_RS00270	COG3539	Fimbrial protein
KONIH1_RS00280	COG3121	Chaperone
KONIH1_RS00295	COG0668	transmembrane transport
KONIH1_RS00310	COG1609	Transcriptional regulator
KONIH1_RS00315	COG2211	Major facilitator Superfamily
KONIH1_RS00320	COG1621	beta-fructofuranosidase activity
KONIH1_RS00340	COG1454	alcohol dehydrogenase
KONIH1_RS00350	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS00355	COG1129	ABC transporter
KONIH1_RS00400	COG2258	MOSC domain
KONIH1_RS00405	COG2205	protein histidine kinase activity
KONIH1_RS00410	COG0745	RESPONSE REGULATOR receiver
KONIH1_RS00415	COG3678	ATP-independent chaperone mediated protein folding
KONIH1_RS00420	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KONIH1_RS00490	COG4695	Portal protein
KONIH1_RS00640	COG1575	Belongs to the MenA family. Type 1 subfamily
KONIH1_RS00655	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KONIH1_RS00660	COG1609	Transcriptional regulator
KONIH1_RS00665	COG3039	Transposase
KONIH1_RS00670	COG1609	Transcriptional regulator
KONIH1_RS00675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KONIH1_RS00690	COG0626	cystathionine gamma-synthase activity
KONIH1_RS00695	COG0460	homoserine dehydrogenase
KONIH1_RS00695	COG0527	aspartate kinase activity
KONIH1_RS00700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KONIH1_RS00705	COG0583	DNA-binding transcription factor activity
KONIH1_RS00715	COG1349	DNA-binding transcription factor activity
KONIH1_RS00720	COG0371	Dehydrogenase
KONIH1_RS00730	COG2207	Transcriptional regulator
KONIH1_RS00735	COG3443	Belongs to the bacterial solute-binding protein 9 family
KONIH1_RS00750	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KONIH1_RS00770	COG0583	DNA-binding transcription factor activity
KONIH1_RS00845	COG3085	chromosome segregation
KONIH1_RS00860	COG3978	acetolactate synthase activity
KONIH1_RS00865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KONIH1_RS00875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KONIH1_RS00880	COG0583	DNA-binding transcription factor activity
KONIH1_RS00890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KONIH1_RS00895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KONIH1_RS00930	COG1397	ADP-ribosylglycohydrolase
KONIH1_RS00950	COG3118	belongs to the thioredoxin family
KONIH1_RS00955	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KONIH1_RS00960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KONIH1_RS00970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KONIH1_RS00975	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KONIH1_RS00980	COG1088	dTDP-glucose 4,6-dehydratase activity
KONIH1_RS00985	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KONIH1_RS00990	COG0456	acetyltransferase
KONIH1_RS00995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KONIH1_RS01000	COG2244	polysaccharide biosynthetic process
KONIH1_RS01045	COG3071	HemY protein
KONIH1_RS01050	COG2959	enzyme of heme biosynthesis
KONIH1_RS01055	COG1587	Uroporphyrinogen-III synthase
KONIH1_RS01065	COG3072	Adenylate cyclase
KONIH1_RS01080	COG0477	Major facilitator Superfamily
KONIH1_RS01085	COG1228	amidohydrolase
KONIH1_RS01095	COG5567	small periplasmic lipoprotein
KONIH1_RS01115	COG1011	Hydrolase
KONIH1_RS01120	COG0210	DNA helicase
KONIH1_RS01125	COG0598	Magnesium transport protein CorA
KONIH1_RS01135	COG2050	protein possibly involved in aromatic compounds catabolism
KONIH1_RS01150	COG1280	lysine exporter protein (LysE YggA)
KONIH1_RS01160	COG1280	lysine exporter protein (LysE YggA)
KONIH1_RS01165	COG2267	carboxylic ester hydrolase activity
KONIH1_RS01170	COG0561	phosphatase activity
KONIH1_RS01175	COG0697	spore germination
KONIH1_RS01180	COG0583	DNA-binding transcription factor activity
KONIH1_RS01195	COG0412	Dienelactone hydrolase
KONIH1_RS01215	COG3165	ubiquinone biosynthetic process from chorismate
KONIH1_RS01225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KONIH1_RS01235	COG0805	protein transport
KONIH1_RS01280	COG1739	Uncharacterized protein family UPF0029
KONIH1_RS01290	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KONIH1_RS01320	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KONIH1_RS01325	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KONIH1_RS01325	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KONIH1_RS01360	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KONIH1_RS01365	COG0250	Participates in transcription elongation, termination and antitermination
KONIH1_RS01400	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KONIH1_RS01405	COG1447	Phosphotransferase system cellobiose-specific component IIA
KONIH1_RS01415	COG3706	GGDEF domain
KONIH1_RS01420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KONIH1_RS01430	COG2104	thiamine diphosphate biosynthetic process
KONIH1_RS01435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KONIH1_RS01450	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KONIH1_RS01490	COG4191	Histidine kinase
KONIH1_RS01500	COG0151	Belongs to the GarS family
KONIH1_RS01540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KONIH1_RS01590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KONIH1_RS01630	COG1187	pseudouridine synthase activity
KONIH1_RS01645	COG4650	regulator
KONIH1_RS01655	COG3541	Predicted nucleotidyltransferase
KONIH1_RS01660	COG0527	aspartate kinase activity
KONIH1_RS01675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KONIH1_RS01685	COG0251	oxidation-reduction process
KONIH1_RS01755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KONIH1_RS01765	COG0534	Mate efflux family protein
KONIH1_RS01770	COG3237	CsbD-like
KONIH1_RS01775	COG0735	belongs to the Fur family
KONIH1_RS01785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KONIH1_RS01800	COG0305	Participates in initiation and elongation during chromosome replication
KONIH1_RS01805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KONIH1_RS01810	COG1448	Aminotransferase
KONIH1_RS01820	COG0432	Pfam Uncharacterised protein family UPF0047
KONIH1_RS01825	COG2315	Protein conserved in bacteria
KONIH1_RS01840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KONIH1_RS01845	COG0629	single-stranded DNA binding
KONIH1_RS01875	COG0366	Alpha amylase catalytic
KONIH1_RS01880	COG3977	Valine--pyruvate aminotransferase
KONIH1_RS01915	COG0741	lytic transglycosylase activity
KONIH1_RS01920	COG4771	TonB-dependent receptor
KONIH1_RS01930	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KONIH1_RS01945	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KONIH1_RS01965	COG2252	PERMEase
KONIH1_RS01970	COG0025	NhaP-type Na H and K H
KONIH1_RS01975	COG0583	DNA-binding transcription factor activity
KONIH1_RS01980	COG1380	Effector of murein hydrolase LrgA
KONIH1_RS01985	COG1346	cytolysis
KONIH1_RS01990	COG3039	Transposase
KONIH1_RS02000	COG3121	Chaperone
KONIH1_RS02030	COG3162	membrane
KONIH1_RS02035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KONIH1_RS02040	COG1301	dicarboxylic acid transport
KONIH1_RS02045	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KONIH1_RS02050	COG3383	formate dehydrogenase (NAD+) activity
KONIH1_RS02055	COG3383	formate dehydrogenase (NAD+) activity
KONIH1_RS02060	COG1940	carbohydrate kinase activity
KONIH1_RS02065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KONIH1_RS02070	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS02075	COG1129	ABC transporter
KONIH1_RS02080	COG1879	ABC-type sugar transport system periplasmic component
KONIH1_RS02085	COG1737	Transcriptional regulator
KONIH1_RS02090	COG0698	ribose 5-phosphate isomerase
KONIH1_RS02100	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KONIH1_RS02105	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KONIH1_RS02110	COG3454	Phosphonate metabolism
KONIH1_RS02115	COG4778	phosphonate C-P lyase system protein PhnL
KONIH1_RS02120	COG4107	phosphonate C-P lyase system protein PhnK
KONIH1_RS02125	COG3627	carbon phosphorus lyase activity
KONIH1_RS02130	COG3626	phosphonate metabolism
KONIH1_RS02135	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
KONIH1_RS02140	COG3624	Phosphonate C-P lyase system protein PhnG
KONIH1_RS02145	COG2188	Transcriptional regulator
KONIH1_RS02150	COG2764	glyoxalase bleomycin resistance protein dioxygenase
KONIH1_RS02155	COG2824	Alkylphosphonate utilization operon protein PhnA
KONIH1_RS02175	COG0861	Integral membrane protein TerC family
KONIH1_RS02190	COG2249	NAD(P)H dehydrogenase (quinone) activity
KONIH1_RS02220	COG1309	transcriptional regulator
KONIH1_RS02235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KONIH1_RS02240	COG1027	Aspartate ammonia-lyase
KONIH1_RS02245	COG3030	protein affecting phage T7 exclusion by the F plasmid
KONIH1_RS02250	COG0531	amino acid
KONIH1_RS02260	COG0459	protein refolding
KONIH1_RS02300	COG3039	Transposase
KONIH1_RS02305	COG1509	lysine 2,3-aminomutase activity
KONIH1_RS02325	COG2076	Multidrug Resistance protein
KONIH1_RS02330	COG3040	lipid binding
KONIH1_RS02345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KONIH1_RS02350	COG1053	succinate dehydrogenase
KONIH1_RS02365	COG1511	domain protein
KONIH1_RS02365	COG3264	Mechanosensitive ion channel
KONIH1_RS02380	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KONIH1_RS02385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS02405	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KONIH1_RS02410	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KONIH1_RS02410	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KONIH1_RS02415	COG0802	atpase or kinase
KONIH1_RS02420	COG0860	N-Acetylmuramoyl-L-alanine amidase
KONIH1_RS02440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KONIH1_RS02445	COG0330	HflC and HflK could
KONIH1_RS02450	COG0330	HflC and HflK could
KONIH1_RS02455	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KONIH1_RS02470	COG0557	exoribonuclease II activity
KONIH1_RS02475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KONIH1_RS02485	COG1960	acyl-CoA dehydrogenase activity
KONIH1_RS02495	COG3650	response to hydrogen peroxide
KONIH1_RS02500	COG1073	alpha beta
KONIH1_RS02560	COG2965	DNA replication, synthesis of RNA primer
KONIH1_RS02565	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KONIH1_RS02570	COG0359	binds to the 23S rRNA
KONIH1_RS02580	COG3061	Opacity-associated protein A
KONIH1_RS02585	COG0545	Peptidyl-prolyl cis-trans isomerase
KONIH1_RS02590	COG1113	amino acid transport
KONIH1_RS02600	COG0697	spore germination
KONIH1_RS02610	COG0702	epimerase
KONIH1_RS02615	COG1733	regulation of RNA biosynthetic process
KONIH1_RS02630	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KONIH1_RS02655	COG1253	flavin adenine dinucleotide binding
KONIH1_RS02665	COG0729	surface antigen
KONIH1_RS02670	COG2911	Protein conserved in bacteria
KONIH1_RS02675	COG2105	PFAM AIG2 family protein
KONIH1_RS02685	COG1879	ABC-type sugar transport system periplasmic component
KONIH1_RS02690	COG1129	ABC transporter
KONIH1_RS02695	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS02700	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS02710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KONIH1_RS02730	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS02740	COG0312	modulator of DNA gyrase
KONIH1_RS02775	COG3964	amidohydrolase
KONIH1_RS02790	COG2706	6-phosphogluconolactonase activity
KONIH1_RS02795	COG3711	transcriptional antiterminator
KONIH1_RS02795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS02815	COG0602	queuosine metabolic process
KONIH1_RS02835	COG1486	melibiose metabolic process
KONIH1_RS02840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KONIH1_RS02845	COG0366	Alpha amylase catalytic
KONIH1_RS02850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS02850	COG1263	PTS System
KONIH1_RS02865	COG0251	oxidation-reduction process
KONIH1_RS02870	COG3397	chitin binding
KONIH1_RS02885	COG2731	YhcH YjgK YiaL family protein
KONIH1_RS02890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KONIH1_RS02915	COG0525	valine-tRNA ligase activity
KONIH1_RS02920	COG2927	DNA polymerase III (CHI subunit)
KONIH1_RS02930	COG0795	lipopolysaccharide-transporting ATPase activity
KONIH1_RS02935	COG0795	lipopolysaccharide-transporting ATPase activity
KONIH1_RS02940	COG0433	COG0433 Predicted ATPase
KONIH1_RS02955	COG3718	enzyme involved in inositol metabolism
KONIH1_RS02960	COG0837	glucose binding
KONIH1_RS02960	COG1737	Transcriptional regulator
KONIH1_RS02965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KONIH1_RS02970	COG3962	Belongs to the TPP enzyme family
KONIH1_RS02980	COG1082	Xylose isomerase domain protein TIM barrel
KONIH1_RS02990	COG2814	Major facilitator Superfamily
KONIH1_RS03000	COG3842	ATPase activity
KONIH1_RS03005	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KONIH1_RS03010	COG0395	ABC-type sugar transport system, permease component
KONIH1_RS03015	COG1175	transmembrane transport
KONIH1_RS03020	COG1064	alcohol dehydrogenase
KONIH1_RS03040	COG0582	viral genome integration into host DNA
KONIH1_RS03050	COG3039	Transposase
KONIH1_RS03120	COG3344	reverse transcriptase
KONIH1_RS03135	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KONIH1_RS03145	COG3039	Transposase
KONIH1_RS03165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KONIH1_RS03170	COG0210	DNA helicase
KONIH1_RS03185	COG4983	Phage plasmid primase, P4 family domain protein
KONIH1_RS03205	COG2003	Belongs to the UPF0758 family
KONIH1_RS03270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KONIH1_RS03275	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS03280	COG4948	Mandelate Racemase Muconate Lactonizing
KONIH1_RS03285	COG0477	Major facilitator Superfamily
KONIH1_RS03295	COG0477	Major facilitator Superfamily
KONIH1_RS03310	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KONIH1_RS03315	COG2850	peptidyl-arginine hydroxylation
KONIH1_RS03345	COG0842	Transport permease protein
KONIH1_RS03350	COG1129	ABC transporter
KONIH1_RS03350	COG0842	Transport permease protein
KONIH1_RS03355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KONIH1_RS03360	COG3706	GGDEF domain
KONIH1_RS03370	COG0814	amino acid
KONIH1_RS03400	COG4869	propanediol catabolic process
KONIH1_RS03410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KONIH1_RS03415	COG1882	Formate acetyltransferase
KONIH1_RS03420	COG1454	alcohol dehydrogenase
KONIH1_RS03420	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS03430	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS03430	COG1454	alcohol dehydrogenase
KONIH1_RS03465	COG2249	NAD(P)H dehydrogenase (quinone) activity
KONIH1_RS03490	COG0531	amino acid
KONIH1_RS03505	COG0732	type I restriction modification DNA specificity domain
KONIH1_RS03525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KONIH1_RS03535	COG1566	PFAM secretion protein HlyD family protein
KONIH1_RS03545	COG0583	DNA-binding transcription factor activity
KONIH1_RS03550	COG3366	ferrous iron transmembrane transporter activity
KONIH1_RS03555	COG0700	Nucleoside recognition
KONIH1_RS03560	COG1473	amidohydrolase
KONIH1_RS03570	COG1924	4 iron, 4 sulfur cluster binding
KONIH1_RS03575	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
KONIH1_RS03585	COG3969	phosphoadenosine phosphosulfate
KONIH1_RS03590	COG1475	DNA binding
KONIH1_RS03595	COG2814	Major facilitator Superfamily
KONIH1_RS03600	COG2733	membrane
KONIH1_RS03610	COG1280	lysine exporter protein (LysE YggA)
KONIH1_RS03620	COG5464	transposase or invertase
KONIH1_RS03625	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS03640	COG0523	cobalamin synthesis protein
KONIH1_RS03645	COG2879	small protein
KONIH1_RS03650	COG1966	Carbon starvation protein
KONIH1_RS03655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KONIH1_RS03660	COG2368	4-hydroxyphenylacetate
KONIH1_RS03680	COG3971	2-oxopent-4-enoate hydratase activity
KONIH1_RS03690	COG3384	dioxygenase
KONIH1_RS03695	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS03705	COG0179	Fumarylacetoacetate (FAA) hydrolase
KONIH1_RS03710	COG1846	Transcriptional regulator
KONIH1_RS03720	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
KONIH1_RS03730	COG4145	pantothenate transmembrane transporter activity
KONIH1_RS03735	COG3734	2-keto-3-deoxy-galactonokinase
KONIH1_RS03740	COG0800	Aldolase
KONIH1_RS03745	COG1737	Transcriptional regulator
KONIH1_RS03755	COG0456	acetyltransferase
KONIH1_RS03760	COG2271	Major facilitator Superfamily
KONIH1_RS03765	COG1802	Transcriptional regulator
KONIH1_RS03770	COG1063	alcohol dehydrogenase
KONIH1_RS03780	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KONIH1_RS03780	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KONIH1_RS03795	COG3715	PTS system
KONIH1_RS03800	COG3716	PTS system mannose fructose sorbose family IID component
KONIH1_RS03805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KONIH1_RS03810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KONIH1_RS03815	COG5464	transposase or invertase
KONIH1_RS03830	COG1484	DNA-dependent DNA replication
KONIH1_RS03845	COG2966	Psort location CytoplasmicMembrane, score
KONIH1_RS03855	COG2207	Transcriptional regulator
KONIH1_RS03860	COG2197	response regulator
KONIH1_RS03865	COG2197	response regulator
KONIH1_RS03870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KONIH1_RS03875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KONIH1_RS03880	COG4114	ferric iron reductase
KONIH1_RS03885	COG3706	GGDEF domain
KONIH1_RS03915	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
KONIH1_RS03920	COG0456	acetyltransferase
KONIH1_RS03925	COG1011	Hydrolase
KONIH1_RS03935	COG2823	Periplasmic or secreted lipoprotein
KONIH1_RS03940	COG4667	esterase of the alpha-beta hydrolase superfamily
KONIH1_RS03945	COG0084	hydrolase, TatD family'
KONIH1_RS03950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KONIH1_RS03970	COG0813	purine-nucleoside phosphorylase activity
KONIH1_RS03980	COG3726	membrane protein affecting hemolysin expression
KONIH1_RS03985	COG0560	Phosphoserine phosphatase
KONIH1_RS04000	COG0488	(ABC) transporter
KONIH1_RS04005	COG0741	lytic transglycosylase activity
KONIH1_RS04025	COG3708	Transcriptional regulator
KONIH1_RS04025	COG2207	Transcriptional regulator
KONIH1_RS04030	COG3045	CreA protein
KONIH1_RS04035	COG0745	RESPONSE REGULATOR receiver
KONIH1_RS04040	COG2205	protein histidine kinase activity
KONIH1_RS04045	COG4452	Inner membrane protein CreD
KONIH1_RS04050	COG0745	RESPONSE REGULATOR receiver
KONIH1_RS04055	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KONIH1_RS04060	COG0527	aspartate kinase activity
KONIH1_RS04060	COG0460	homoserine dehydrogenase
KONIH1_RS04070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KONIH1_RS04080	COG1115	amino acid carrier protein
KONIH1_RS04085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KONIH1_RS04090	COG0521	Mo-molybdopterin cofactor biosynthetic process
KONIH1_RS04095	COG0477	Major facilitator Superfamily
KONIH1_RS04100	COG1584	GPR1 FUN34 yaaH family protein
KONIH1_RS04105	COG4735	regulation of single-species biofilm formation
KONIH1_RS04165	COG0583	DNA-binding transcription factor activity
KONIH1_RS04175	COG0196	riboflavin kinase activity
KONIH1_RS04190	COG1047	Peptidyl-prolyl cis-trans
KONIH1_RS04205	COG0583	DNA-binding transcription factor activity
KONIH1_RS04210	COG2828	Protein conserved in bacteria
KONIH1_RS04215	COG0471	metal ion transport
KONIH1_RS04220	COG0471	metal ion transport
KONIH1_RS04225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KONIH1_RS04235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KONIH1_RS04255	COG0511	ligase activity, forming carbon-carbon bonds
KONIH1_RS04255	COG5016	pyruvate
KONIH1_RS04360	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KONIH1_RS04375	COG3493	citrate carrier protein
KONIH1_RS04385	COG0564	pseudouridine synthase activity
KONIH1_RS04395	COG0417	DNA replication proofreading
KONIH1_RS04400	COG0235	Class ii aldolase
KONIH1_RS04420	COG0586	Pfam SNARE associated Golgi protein
KONIH1_RS04430	COG1178	ABC-type Fe3 transport system permease component
KONIH1_RS04445	COG2814	Major facilitator Superfamily
KONIH1_RS04450	COG2271	Major facilitator Superfamily
KONIH1_RS04455	COG0583	DNA-binding transcription factor activity
KONIH1_RS04465	COG0738	Major facilitator superfamily
KONIH1_RS04470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KONIH1_RS04495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KONIH1_RS04505	COG0028	Belongs to the TPP enzyme family
KONIH1_RS04515	COG1609	Transcriptional regulator
KONIH1_RS04535	COG0768	penicillin binding
KONIH1_RS04545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KONIH1_RS04560	COG0772	Belongs to the SEDS family
KONIH1_RS04585	COG0849	cell division
KONIH1_RS04590	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KONIH1_RS04610	COG0494	nUDIX hydrolase
KONIH1_RS04615	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KONIH1_RS04635	COG1459	type II secretion system
KONIH1_RS04640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KONIH1_RS04645	COG4969	Belongs to the N-Me-Phe pilin family
KONIH1_RS04660	COG3725	Membrane protein required for beta-lactamase induction
KONIH1_RS04665	COG3940	Belongs to the glycosyl hydrolase 43 family
KONIH1_RS04670	COG2211	Major facilitator Superfamily
KONIH1_RS04675	COG1113	amino acid transport
KONIH1_RS04680	COG2186	Transcriptional regulator
KONIH1_RS04685	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KONIH1_RS04690	COG0508	dehydrogenase complex catalyzes the overall conversion of
KONIH1_RS04695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KONIH1_RS04710	COG3064	Membrane
KONIH1_RS04740	COG1349	DNA-binding transcription factor activity
KONIH1_RS04755	COG0545	Peptidyl-prolyl cis-trans isomerase
KONIH1_RS04770	COG2132	Multicopper oxidase
KONIH1_RS04775	COG4993	Dehydrogenase
KONIH1_RS04785	COG0288	reversible hydration of carbon dioxide
KONIH1_RS04790	COG1131	(ABC) transporter
KONIH1_RS04795	COG0842	Transport permease protein
KONIH1_RS04800	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS04805	COG0726	polysaccharide deacetylase
KONIH1_RS04830	COG3188	usher protein
KONIH1_RS04835	COG3121	Chaperone
KONIH1_RS04840	COG3539	Fimbrial protein
KONIH1_RS04860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KONIH1_RS04865	COG0617	tRNA 3'-terminal CCA addition
KONIH1_RS04885	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KONIH1_RS04890	COG1643	Atp-dependent helicase
KONIH1_RS04980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KONIH1_RS04985	COG4774	siderophore transport
KONIH1_RS04990	COG1120	ATPase activity
KONIH1_RS04995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KONIH1_RS05000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KONIH1_RS05025	COG2860	membrane
KONIH1_RS05045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KONIH1_RS05050	COG3835	regulator
KONIH1_RS05070	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KONIH1_RS05075	COG0024	Methionine aminopeptidase
KONIH1_RS05085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KONIH1_RS05110	COG0575	Belongs to the CDS family
KONIH1_RS05115	COG0750	zinc metalloprotease
KONIH1_RS05125	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
KONIH1_RS05130	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KONIH1_RS05170	COG1982	Orn Lys Arg decarboxylase major
KONIH1_RS05175	COG0346	lactoylglutathione lyase activity
KONIH1_RS05185	COG4568	rho-dependent transcription termination
KONIH1_RS05195	COG4681	YaeQ
KONIH1_RS05200	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KONIH1_RS05205	COG3015	lipoprotein NlpE involved in copper resistance
KONIH1_RS05210	COG0791	NLP P60 protein
KONIH1_RS05220	COG1720	tRNA m6t6A37 methyltransferase activity
KONIH1_RS05230	COG1464	Belongs to the NlpA lipoprotein family
KONIH1_RS05235	COG2011	ABC-type metal ion transport system permease component
KONIH1_RS05245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KONIH1_RS05285	COG0583	DNA-binding transcription factor activity
KONIH1_RS05290	COG2814	Major facilitator Superfamily
KONIH1_RS05300	COG2226	methyltransferase
KONIH1_RS05305	COG1388	LysM domain
KONIH1_RS05305	COG0741	lytic transglycosylase activity
KONIH1_RS05315	COG2226	methyltransferase
KONIH1_RS05335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KONIH1_RS05350	COG0121	glutamine amidotransferase
KONIH1_RS05355	COG3034	peptidoglycan biosynthetic process
KONIH1_RS05370	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KONIH1_RS05375	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KONIH1_RS05390	COG2991	Protein conserved in bacteria
KONIH1_RS05405	COG0454	-acetyltransferase
KONIH1_RS05410	COG2195	Cleaves the N-terminal amino acid of tripeptides
KONIH1_RS05430	COG1045	serine acetyltransferase
KONIH1_RS05445	COG0297	glycogen (starch) synthase activity
KONIH1_RS05445	COG0438	transferase activity, transferring glycosyl groups
KONIH1_RS05450	COG0438	transferase activity, transferring glycosyl groups
KONIH1_RS05455	COG0463	Glycosyl transferase, family 2
KONIH1_RS05475	COG1596	polysaccharide export
KONIH1_RS05485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KONIH1_RS05490	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS05510	COG2186	Transcriptional regulator
KONIH1_RS05515	COG0246	Mannitol dehydrogenase
KONIH1_RS05530	COG3153	acetyltransferase
KONIH1_RS05535	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KONIH1_RS05585	COG0477	Major facilitator Superfamily
KONIH1_RS05595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KONIH1_RS05605	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KONIH1_RS05610	COG0402	S-adenosylhomocysteine deaminase activity
KONIH1_RS05615	COG2188	Transcriptional regulator
KONIH1_RS05625	COG2986	histidine ammonia-lyase
KONIH1_RS05655	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KONIH1_RS05670	COG2801	Transposase and inactivated derivatives
KONIH1_RS05705	COG0582	viral genome integration into host DNA
KONIH1_RS05715	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KONIH1_RS05740	COG2375	cellular response to nickel ion
KONIH1_RS05750	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KONIH1_RS05825	COG3039	Transposase
KONIH1_RS05830	COG3596	GTP binding
KONIH1_RS05835	COG2378	regulation of single-species biofilm formation
KONIH1_RS05865	COG2003	Belongs to the UPF0758 family
KONIH1_RS05915	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KONIH1_RS05920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KONIH1_RS05925	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KONIH1_RS05930	COG0791	NLP P60 protein
KONIH1_RS05935	COG0583	DNA-binding transcription factor activity
KONIH1_RS05940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KONIH1_RS05950	COG1116	anion transmembrane transporter activity
KONIH1_RS05975	COG3639	organic phosphonate transmembrane transporter activity
KONIH1_RS05985	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KONIH1_RS06010	COG3188	usher protein
KONIH1_RS06025	COG0765	amino acid transport
KONIH1_RS06030	COG0765	amino acid transport
KONIH1_RS06035	COG1126	abc transporter atp-binding protein
KONIH1_RS06040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS06075	COG4302	ethanolamine ammonia-lyase activity
KONIH1_RS06080	COG4303	Ethanolamine ammonia lyase large subunit
KONIH1_RS06090	COG5434	Belongs to the glycosyl hydrolase 28 family
KONIH1_RS06095	COG0833	amino acid
KONIH1_RS06100	COG2040	homocysteine
KONIH1_RS06105	COG3842	ATPase activity
KONIH1_RS06115	COG1840	ABC-type Fe3 transport system, periplasmic component
KONIH1_RS06120	COG2271	Major facilitator Superfamily
KONIH1_RS06135	COG4521	taurine ABC transporter
KONIH1_RS06140	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KONIH1_RS06145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KONIH1_RS06150	COG2175	clavaminate synthase activity
KONIH1_RS06160	COG0113	porphobilinogen synthase activity
KONIH1_RS06165	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KONIH1_RS06175	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KONIH1_RS06210	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS06220	COG1609	Transcriptional regulator
KONIH1_RS06230	COG1785	Belongs to the alkaline phosphatase family
KONIH1_RS06240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KONIH1_RS06250	COG3416	Protein conserved in bacteria
KONIH1_RS06255	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KONIH1_RS06265	COG4126	flavin adenine dinucleotide binding
KONIH1_RS06280	COG1940	carbohydrate kinase activity
KONIH1_RS06290	COG0419	ATPase involved in DNA repair
KONIH1_RS06295	COG0420	3'-5' exonuclease activity
KONIH1_RS06320	COG0366	Alpha amylase catalytic
KONIH1_RS06325	COG0583	DNA-binding transcription factor activity
KONIH1_RS06330	COG1335	isochorismatase
KONIH1_RS06340	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KONIH1_RS06355	COG0450	alkyl hydroperoxide reductase
KONIH1_RS06360	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
KONIH1_RS06375	COG1862	Preprotein translocase
KONIH1_RS06385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KONIH1_RS06410	COG4238	major outer membrane lipoprotein
KONIH1_RS06420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KONIH1_RS06420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KONIH1_RS06440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KONIH1_RS06445	COG0667	Aldo Keto reductase
KONIH1_RS06455	COG0142	geranyltranstransferase activity
KONIH1_RS06475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KONIH1_RS06485	COG2814	Major facilitator Superfamily
KONIH1_RS06490	COG0673	inositol 2-dehydrogenase activity
KONIH1_RS06495	COG2211	Major facilitator Superfamily
KONIH1_RS06520	COG1053	succinate dehydrogenase
KONIH1_RS06530	COG1414	Transcriptional regulator
KONIH1_RS06545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KONIH1_RS06550	COG1845	cytochrome c oxidase, subunit III
KONIH1_RS06555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KONIH1_RS06560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KONIH1_RS06565	COG2223	nitrite transmembrane transporter activity
KONIH1_RS06570	COG3056	Lipoprotein
KONIH1_RS06575	COG0271	Belongs to the BolA IbaG family
KONIH1_RS06595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KONIH1_RS06600	COG0776	regulation of translation
KONIH1_RS06605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KONIH1_RS06610	COG1555	photosystem II stabilization
KONIH1_RS06615	COG0824	Thioesterase
KONIH1_RS06625	COG4533	DNA binding
KONIH1_RS06640	COG1522	sequence-specific DNA binding
KONIH1_RS06645	COG1132	(ABC) transporter
KONIH1_RS06650	COG1132	(ABC) transporter
KONIH1_RS06660	COG0347	Belongs to the P(II) protein family
KONIH1_RS06665	COG0004	ammonium transporteR
KONIH1_RS06670	COG1946	Acyl-CoA thioesterase
KONIH1_RS06675	COG3126	Type III secretion system lipoprotein chaperone (YscW)
KONIH1_RS06680	COG3695	enzyme binding
KONIH1_RS06705	COG2364	Membrane
KONIH1_RS06725	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KONIH1_RS06735	COG2182	Extracellular solute-binding protein
KONIH1_RS06740	COG1175	transmembrane transport
KONIH1_RS06745	COG3833	ABC-type maltose transport systems, permease component
KONIH1_RS06750	COG3867	Arabinogalactan endo-beta-1,4-galactanase
KONIH1_RS06755	COG1874	Beta-galactosidase
KONIH1_RS06760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS06760	COG1263	PTS System
KONIH1_RS06780	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KONIH1_RS06800	COG0110	maltose O-acetyltransferase activity
KONIH1_RS06815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KONIH1_RS06820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KONIH1_RS06825	COG1309	transcriptional regulator
KONIH1_RS06830	COG3264	Mechanosensitive ion channel
KONIH1_RS06830	COG1196	nuclear chromosome segregation
KONIH1_RS06840	COG3923	Primosomal replication protein n
KONIH1_RS06845	COG2832	Protein of unknown function (DUF454)
KONIH1_RS06885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KONIH1_RS06890	COG4651	solute:proton antiporter activity
KONIH1_RS06890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KONIH1_RS06895	COG2223	nitrite transmembrane transporter activity
KONIH1_RS06905	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KONIH1_RS06910	COG3735	TraB family
KONIH1_RS06930	COG0811	peptide transport
KONIH1_RS06960	COG1585	Membrane protein implicated in regulation of membrane protease activity
KONIH1_RS06965	COG0330	HflC and HflK could
KONIH1_RS06970	COG4619	ABC transporter
KONIH1_RS06975	COG0390	transport system, permease component
KONIH1_RS06980	COG3118	belongs to the thioredoxin family
KONIH1_RS06985	COG0300	oxidoreductase activity
KONIH1_RS06990	COG2755	lipolytic protein G-D-S-L family
KONIH1_RS06995	COG4181	ATPase activity
KONIH1_RS07000	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KONIH1_RS07020	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KONIH1_RS07025	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KONIH1_RS07035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KONIH1_RS07045	COG2501	S4 domain
KONIH1_RS07060	COG2808	Putative FMN-binding domain
KONIH1_RS07070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KONIH1_RS07080	COG0583	DNA-binding transcription factor activity
KONIH1_RS07090	COG3710	Transcriptional regulator
KONIH1_RS07095	COG0531	amino acid
KONIH1_RS07105	COG3104	oligopeptide transport
KONIH1_RS07120	COG2367	Beta-lactamase
KONIH1_RS07130	COG0673	inositol 2-dehydrogenase activity
KONIH1_RS07145	COG1129	ABC transporter
KONIH1_RS07150	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS07155	COG1263	PTS System
KONIH1_RS07155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS07155	COG2190	(PTS) system
KONIH1_RS07160	COG2723	6-phospho-beta-galactosidase activity
KONIH1_RS07165	COG3711	transcriptional antiterminator
KONIH1_RS07195	COG1120	ATPase activity
KONIH1_RS07200	COG4139	cobalamin transport
KONIH1_RS07225	COG1473	amidohydrolase
KONIH1_RS07230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS07235	COG0667	Aldo Keto reductase
KONIH1_RS07245	COG1113	amino acid transport
KONIH1_RS07250	COG2211	Major facilitator Superfamily
KONIH1_RS07270	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS07275	COG0583	DNA-binding transcription factor activity
KONIH1_RS07280	COG2771	luxR family
KONIH1_RS07295	COG3188	usher protein
KONIH1_RS07315	COG0494	nUDIX hydrolase
KONIH1_RS07325	COG0668	transmembrane transport
KONIH1_RS07330	COG0477	Major facilitator Superfamily
KONIH1_RS07340	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KONIH1_RS07340	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KONIH1_RS07350	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS07350	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS07355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS07360	COG3715	PTS system
KONIH1_RS07365	COG3716	PTS system mannose fructose sorbose family IID component
KONIH1_RS07370	COG1621	beta-fructofuranosidase activity
KONIH1_RS07440	COG0778	Nitroreductase
KONIH1_RS07445	COG2315	Protein conserved in bacteria
KONIH1_RS07465	COG4774	siderophore transport
KONIH1_RS07495	COG3698	Phosphodiester glycosidase
KONIH1_RS07515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KONIH1_RS07520	COG4608	Belongs to the ABC transporter superfamily
KONIH1_RS07525	COG0444	Belongs to the ABC transporter superfamily
KONIH1_RS07570	COG0765	amino acid transport
KONIH1_RS07575	COG0765	amino acid transport
KONIH1_RS07585	COG4221	oxidoreductase activity
KONIH1_RS07590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KONIH1_RS07595	COG4608	Belongs to the ABC transporter superfamily
KONIH1_RS07600	COG0444	Belongs to the ABC transporter superfamily
KONIH1_RS07605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KONIH1_RS07610	COG0601	transmembrane transport
KONIH1_RS07640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KONIH1_RS07650	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS07655	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS07660	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS07665	COG1129	ABC transporter
KONIH1_RS07675	COG1879	ABC-type sugar transport system periplasmic component
KONIH1_RS07680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KONIH1_RS07685	COG2390	Transcriptional regulator
KONIH1_RS07690	COG3959	Transketolase, thiamine diphosphate binding domain
KONIH1_RS07695	COG3958	Transketolase
KONIH1_RS07700	COG2977	Belongs to the P-Pant transferase superfamily
KONIH1_RS07705	COG4771	TonB-dependent receptor
KONIH1_RS07710	COG2382	esterase
KONIH1_RS07715	COG3251	PFAM MbtH domain protein
KONIH1_RS07720	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KONIH1_RS07720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KONIH1_RS07725	COG1120	ATPase activity
KONIH1_RS07730	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KONIH1_RS07735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KONIH1_RS07750	COG4592	Periplasmic binding protein
KONIH1_RS07755	COG1169	isochorismate synthase
KONIH1_RS07760	COG1021	2,3-dihydroxybenzoate-AMP ligase
KONIH1_RS07765	COG1535	isochorismatase
KONIH1_RS07765	COG3433	isochorismatase activity
KONIH1_RS07770	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS07780	COG1966	Carbon starvation protein
KONIH1_RS07785	COG2879	small protein
KONIH1_RS07795	COG0371	Dehydrogenase
KONIH1_RS07800	COG1129	ABC transporter
KONIH1_RS07805	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS07835	COG2271	Major facilitator Superfamily
KONIH1_RS07840	COG0483	inositol monophosphate 1-phosphatase activity
KONIH1_RS07850	COG0402	S-adenosylhomocysteine deaminase activity
KONIH1_RS07860	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KONIH1_RS07875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KONIH1_RS07885	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS07890	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS07895	COG1129	ABC transporter
KONIH1_RS07910	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KONIH1_RS07915	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KONIH1_RS07920	COG0436	Aminotransferase
KONIH1_RS07925	COG1475	DNA binding
KONIH1_RS07930	COG3969	phosphoadenosine phosphosulfate
KONIH1_RS07935	COG0583	DNA-binding transcription factor activity
KONIH1_RS07945	COG3634	alkyl hydroperoxide reductase activity
KONIH1_RS07955	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KONIH1_RS07960	COG3719	Belongs to the RNase T2 family
KONIH1_RS07965	COG3069	C4-dicarboxylate transmembrane transporter activity
KONIH1_RS07985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KONIH1_RS07990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KONIH1_RS08000	COG0583	DNA-binding transcription factor activity
KONIH1_RS08015	COG1686	Belongs to the peptidase S11 family
KONIH1_RS08020	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KONIH1_RS08025	COG0772	Belongs to the SEDS family
KONIH1_RS08030	COG0768	penicillin binding
KONIH1_RS08040	COG0799	negative regulation of ribosome biogenesis
KONIH1_RS08055	COG1466	dna polymerase III delta subunit
KONIH1_RS08070	COG2888	peptidyl-tyrosine sulfation
KONIH1_RS08080	COG2831	hemolysin activation secretion protein
KONIH1_RS08085	COG1126	abc transporter atp-binding protein
KONIH1_RS08090	COG0765	amino acid transport
KONIH1_RS08095	COG0765	amino acid transport
KONIH1_RS08110	COG4535	Mg2 and Co2 transporter CorC
KONIH1_RS08115	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KONIH1_RS08120	COG1702	phosphate starvation-inducible protein PhoH
KONIH1_RS08130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KONIH1_RS08170	COG0367	asparagine synthase
KONIH1_RS08175	COG0647	UMP catabolic process
KONIH1_RS08180	COG1846	Transcriptional regulator
KONIH1_RS08180	COG1940	carbohydrate kinase activity
KONIH1_RS08185	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KONIH1_RS08225	COG1053	succinate dehydrogenase
KONIH1_RS08230	COG0583	DNA-binding transcription factor activity
KONIH1_RS08235	COG0735	belongs to the Fur family
KONIH1_RS08250	COG0596	Alpha beta hydrolase
KONIH1_RS08255	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KONIH1_RS08260	COG0033	Phosphoglucomutase
KONIH1_RS08270	COG1349	DNA-binding transcription factor activity
KONIH1_RS08275	COG1063	alcohol dehydrogenase
KONIH1_RS08280	COG1879	ABC-type sugar transport system periplasmic component
KONIH1_RS08285	COG1129	ABC transporter
KONIH1_RS08290	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS08295	COG1070	Carbohydrate kinase
KONIH1_RS08300	COG3623	hexulose-6-phosphate isomerase
KONIH1_RS08310	COG0745	RESPONSE REGULATOR receiver
KONIH1_RS08315	COG2205	protein histidine kinase activity
KONIH1_RS08345	COG0415	Belongs to the DNA photolyase family
KONIH1_RS08355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KONIH1_RS08360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KONIH1_RS08365	COG1984	allophanate hydrolase subunit 2
KONIH1_RS08395	COG0372	Belongs to the citrate synthase family
KONIH1_RS08405	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KONIH1_RS08410	COG1053	succinate dehydrogenase
KONIH1_RS08415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KONIH1_RS08420	COG0567	Dehydrogenase, E1 component
KONIH1_RS08425	COG0508	dehydrogenase complex catalyzes the overall conversion of
KONIH1_RS08435	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KONIH1_RS08445	COG0583	DNA-binding transcription factor activity
KONIH1_RS08455	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KONIH1_RS08455	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KONIH1_RS08465	COG1301	dicarboxylic acid transport
KONIH1_RS08480	COG3799	methylaspartate ammonia-lyase activity
KONIH1_RS08485	COG4865	methylaspartate mutase activity
KONIH1_RS08495	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KONIH1_RS08505	COG3039	Transposase
KONIH1_RS08510	COG1271	oxidase subunit
KONIH1_RS08515	COG1294	oxidase, subunit
KONIH1_RS08520	COG3790	cyd operon protein YbgE
KONIH1_RS08525	COG0824	Thioesterase
KONIH1_RS08530	COG0811	peptide transport
KONIH1_RS08535	COG0848	biopolymer transport protein
KONIH1_RS08540	COG3064	Membrane
KONIH1_RS08550	COG2885	chlorophyll binding
KONIH1_RS08555	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KONIH1_RS08585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KONIH1_RS08605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KONIH1_RS08615	COG2017	converts alpha-aldose to the beta-anomer
KONIH1_RS08625	COG1085	galactose-1-phosphate uridylyltransferase
KONIH1_RS08630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KONIH1_RS08635	COG1119	ATPase activity
KONIH1_RS08640	COG3585	molybdate ion transport
KONIH1_RS08640	COG2005	Transcriptional regulator
KONIH1_RS08650	COG0725	ABC transporter, periplasmic molybdate-binding protein
KONIH1_RS08655	COG4149	molybdate abc transporter
KONIH1_RS08665	COG0561	phosphatase activity
KONIH1_RS08700	COG2200	EAL domain
KONIH1_RS08705	COG0789	Transcriptional regulator
KONIH1_RS08720	COG4677	pectinesterase activity
KONIH1_RS08750	COG1881	PFAM PEBP family protein
KONIH1_RS08755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KONIH1_RS08770	COG2226	methyltransferase
KONIH1_RS08795	COG0745	RESPONSE REGULATOR receiver
KONIH1_RS08815	COG0521	Mo-molybdopterin cofactor biosynthetic process
KONIH1_RS08825	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KONIH1_RS08830	COG0314	molybdopterin synthase activity
KONIH1_RS08835	COG0670	Belongs to the BI1 family
KONIH1_RS08840	COG0392	lysyltransferase activity
KONIH1_RS08845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KONIH1_RS08850	COG3568	Endonuclease Exonuclease Phosphatase
KONIH1_RS08860	COG0842	Transport permease protein
KONIH1_RS08865	COG0842	Transport permease protein
KONIH1_RS08870	COG1131	(ABC) transporter
KONIH1_RS08875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KONIH1_RS08880	COG1309	transcriptional regulator
KONIH1_RS08885	COG0583	DNA-binding transcription factor activity
KONIH1_RS08890	COG2271	Major facilitator Superfamily
KONIH1_RS08895	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS08900	COG3959	Transketolase, thiamine diphosphate binding domain
KONIH1_RS08905	COG3958	Transketolase
KONIH1_RS08910	COG0513	Belongs to the DEAD box helicase family
KONIH1_RS08920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KONIH1_RS08930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KONIH1_RS08940	COG4774	siderophore transport
KONIH1_RS08955	COG0668	transmembrane transport
KONIH1_RS08965	COG1126	abc transporter atp-binding protein
KONIH1_RS08970	COG0765	amino acid transport
KONIH1_RS08975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS08990	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KONIH1_RS08995	COG2194	sulfuric ester hydrolase activity
KONIH1_RS09010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KONIH1_RS09015	COG0667	Aldo Keto reductase
KONIH1_RS09020	COG2723	6-phospho-beta-galactosidase activity
KONIH1_RS09025	COG2188	Transcriptional regulator
KONIH1_RS09030	COG1376	ErfK ybiS ycfS ynhG family protein
KONIH1_RS09060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KONIH1_RS09065	COG0488	(ABC) transporter
KONIH1_RS09075	COG2271	Major facilitator Superfamily
KONIH1_RS09080	COG1609	Transcriptional regulator
KONIH1_RS09090	COG0561	phosphatase activity
KONIH1_RS09095	COG1882	Formate acetyltransferase
KONIH1_RS09100	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KONIH1_RS09105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KONIH1_RS09110	COG0303	'Molybdopterin
KONIH1_RS09115	COG1446	asparaginase
KONIH1_RS09125	COG0747	negative chemotaxis
KONIH1_RS09160	COG2133	pyrroloquinoline quinone binding
KONIH1_RS09165	COG0625	glutathione transferase activity
KONIH1_RS09170	COG0582	viral genome integration into host DNA
KONIH1_RS09235	COG1846	Transcriptional regulator
KONIH1_RS09340	COG3039	Transposase
KONIH1_RS09370	COG0740	serine-type endopeptidase activity
KONIH1_RS09410	COG1196	nuclear chromosome segregation
KONIH1_RS09460	COG1686	Belongs to the peptidase S11 family
KONIH1_RS09465	COG1349	DNA-binding transcription factor activity
KONIH1_RS09470	COG0671	phosphoesterase, PA-phosphatase related
KONIH1_RS09475	COG2814	Major facilitator Superfamily
KONIH1_RS09480	COG0561	phosphatase activity
KONIH1_RS09485	COG0738	Major facilitator superfamily
KONIH1_RS09490	COG3226	Transcriptional regulator
KONIH1_RS09505	COG3039	Transposase
KONIH1_RS09515	COG1192	Involved in chromosome partitioning
KONIH1_RS09570	COG0778	Nitroreductase
KONIH1_RS09585	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KONIH1_RS09590	COG3842	ATPase activity
KONIH1_RS09595	COG1176	ABC-type spermidine putrescine transport system, permease component I
KONIH1_RS09600	COG1177	transmembrane transport
KONIH1_RS09615	COG0745	RESPONSE REGULATOR receiver
KONIH1_RS09620	COG5002	protein histidine kinase activity
KONIH1_RS09625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS09630	COG4160	amino acid transport
KONIH1_RS09635	COG4215	(ABC) transporter
KONIH1_RS09640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS09645	COG1126	abc transporter atp-binding protein
KONIH1_RS09655	COG0393	Putative heavy-metal-binding
KONIH1_RS09660	COG3023	N-Acetylmuramoyl-L-alanine amidase
KONIH1_RS09665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KONIH1_RS09670	COG0702	epimerase
KONIH1_RS09675	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
KONIH1_RS09680	COG0028	Belongs to the TPP enzyme family
KONIH1_RS09690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KONIH1_RS09700	COG2431	L-lysine efflux transmembrane transporter activity
KONIH1_RS09705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KONIH1_RS09710	COG3593	DNA synthesis involved in DNA repair
KONIH1_RS09715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KONIH1_RS09725	COG1278	Cold shock
KONIH1_RS09735	COG0542	response to heat
KONIH1_RS09740	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KONIH1_RS09750	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KONIH1_RS09755	COG4988	ABC transporter
KONIH1_RS09760	COG0492	ferredoxin-NADP+ reductase activity
KONIH1_RS09770	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KONIH1_RS09770	COG1674	ftsk spoiiie
KONIH1_RS09780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KONIH1_RS09790	COG0243	molybdopterin cofactor binding
KONIH1_RS09795	COG0437	4 iron, 4 sulfur cluster binding
KONIH1_RS09800	COG3302	dmso reductase anchor subunit
KONIH1_RS09805	COG0477	Major facilitator Superfamily
KONIH1_RS09810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS09815	COG3958	Transketolase
KONIH1_RS09820	COG3959	Transketolase, thiamine diphosphate binding domain
KONIH1_RS09840	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KONIH1_RS09845	COG1882	Formate acetyltransferase
KONIH1_RS09850	COG2116	formate transmembrane transporter activity
KONIH1_RS09855	COG1944	ATP diphosphatase activity
KONIH1_RS09860	COG2323	membrane
KONIH1_RS09880	COG0539	negative regulation of cytoplasmic translation
KONIH1_RS09890	COG2333	competence protein COMEC
KONIH1_RS09890	COG0658	competence protein
KONIH1_RS09895	COG1132	(ABC) transporter
KONIH1_RS09905	COG3214	Protein conserved in bacteria
KONIH1_RS09920	COG3173	Aminoglycoside phosphotransferase
KONIH1_RS09925	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KONIH1_RS09930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KONIH1_RS09940	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KONIH1_RS09950	COG2989	Protein conserved in bacteria
KONIH1_RS09960	COG3108	Peptidase M15
KONIH1_RS09965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KONIH1_RS09980	COG1448	Aminotransferase
KONIH1_RS09985	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KONIH1_RS10000	COG0308	aminopeptidase N
KONIH1_RS10005	COG1116	anion transmembrane transporter activity
KONIH1_RS10010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KONIH1_RS10015	COG0431	NADPH-dependent FMN reductase
KONIH1_RS10030	COG0633	Ferredoxin
KONIH1_RS10030	COG3217	Mosc domain protein beta barrel domain protein
KONIH1_RS10040	COG0488	(ABC) transporter
KONIH1_RS10045	COG2995	paraquat-inducible protein a
KONIH1_RS10050	COG3008	intermembrane lipid transfer
KONIH1_RS10050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KONIH1_RS10055	COG3009	Protein conserved in bacteria
KONIH1_RS10065	COG1067	ATP-dependent peptidase activity
KONIH1_RS10090	COG3070	regulator of competence-specific genes
KONIH1_RS10095	COG1289	transmembrane transporter activity
KONIH1_RS10100	COG3304	Inner membrane component domain
KONIH1_RS10105	COG0210	DNA helicase
KONIH1_RS10115	COG1832	CoA-binding protein
KONIH1_RS10135	COG2274	protein secretion by the type I secretion system
KONIH1_RS10140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KONIH1_RS10145	COG3039	Transposase
KONIH1_RS10150	COG0438	transferase activity, transferring glycosyl groups
KONIH1_RS10175	COG1881	PFAM PEBP family protein
KONIH1_RS10180	COG2207	Transcriptional regulator
KONIH1_RS10195	COG0670	Belongs to the BI1 family
KONIH1_RS10220	COG4821	SIS domain
KONIH1_RS10230	COG4821	SIS domain
KONIH1_RS10235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS10240	COG3716	PTS system mannose fructose sorbose family IID component
KONIH1_RS10245	COG3715	PTS system
KONIH1_RS10255	COG2188	Transcriptional regulator
KONIH1_RS10260	COG0436	Aminotransferase
KONIH1_RS10265	COG0504	CTP synthase activity
KONIH1_RS10270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KONIH1_RS10275	COG0006	proline dipeptidase activity
KONIH1_RS10285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KONIH1_RS10290	COG1126	abc transporter atp-binding protein
KONIH1_RS10295	COG0765	amino acid transport
KONIH1_RS10300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS10310	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS10325	COG2207	Transcriptional regulator
KONIH1_RS10330	COG1486	melibiose metabolic process
KONIH1_RS10355	COG0814	amino acid
KONIH1_RS10360	COG0156	8-amino-7-oxononanoate synthase activity
KONIH1_RS10390	COG1126	abc transporter atp-binding protein
KONIH1_RS10395	COG0765	amino acid transport
KONIH1_RS10420	COG1278	Cold shock
KONIH1_RS10450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KONIH1_RS10460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KONIH1_RS10530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KONIH1_RS10535	COG2233	PERMEase
KONIH1_RS10545	COG2351	hydroxyisourate hydrolase activity
KONIH1_RS10550	COG0402	S-adenosylhomocysteine deaminase activity
KONIH1_RS10555	COG1953	Uracil, thiamine, allantoin
KONIH1_RS10610	COG0765	amino acid transport
KONIH1_RS10620	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KONIH1_RS10635	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KONIH1_RS10645	COG1605	Chorismate mutase
KONIH1_RS10645	COG0287	Prephenate dehydrogenase
KONIH1_RS10655	COG3706	GGDEF domain
KONIH1_RS10660	COG2207	Transcriptional regulator
KONIH1_RS10670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KONIH1_RS10675	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KONIH1_RS10680	COG1882	Formate acetyltransferase
KONIH1_RS10685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KONIH1_RS10690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KONIH1_RS10695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KONIH1_RS10695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS10695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS10700	COG0473	3-isopropylmalate dehydrogenase activity
KONIH1_RS10705	COG0583	DNA-binding transcription factor activity
KONIH1_RS10710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KONIH1_RS10715	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS10720	COG1917	Cupin 2, conserved barrel domain protein
KONIH1_RS10720	COG1396	sequence-specific DNA binding
KONIH1_RS10725	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KONIH1_RS10730	COG0174	glutamine synthetase
KONIH1_RS10735	COG0531	amino acid
KONIH1_RS10765	COG3729	General stress protein
KONIH1_RS10770	COG2233	PERMEase
KONIH1_RS10805	COG1309	transcriptional regulator
KONIH1_RS10820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KONIH1_RS10830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KONIH1_RS10840	COG2822	iron ion transport
KONIH1_RS10850	COG1702	phosphate starvation-inducible protein PhoH
KONIH1_RS10870	COG3850	Histidine kinase
KONIH1_RS10870	COG5002	protein histidine kinase activity
KONIH1_RS10890	COG1335	isochorismatase
KONIH1_RS10900	COG0583	DNA-binding transcription factor activity
KONIH1_RS10920	COG3381	protein complex oligomerization
KONIH1_RS10960	COG5645	(Lipo)protein
KONIH1_RS10975	COG1560	Kdo2-lipid A biosynthetic process
KONIH1_RS11010	COG2999	glutathione oxidoreductase activity
KONIH1_RS11020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KONIH1_RS11030	COG0673	inositol 2-dehydrogenase activity
KONIH1_RS11040	COG2814	Major facilitator Superfamily
KONIH1_RS11045	COG0583	DNA-binding transcription factor activity
KONIH1_RS11050	COG1530	ribonuclease E activity
KONIH1_RS11065	COG0424	maF-like protein
KONIH1_RS11070	COG1399	metal-binding, possibly nucleic acid-binding protein
KONIH1_RS11090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KONIH1_RS11105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KONIH1_RS11110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KONIH1_RS11115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KONIH1_RS11125	COG0470	DNA polymerase III
KONIH1_RS11130	COG0084	hydrolase, TatD family'
KONIH1_RS11140	COG4773	Receptor
KONIH1_RS11145	COG0537	adenosine 5'-monophosphoramidase activity
KONIH1_RS11150	COG5633	Lipoprotein
KONIH1_RS11175	COG1252	NADH dehydrogenase
KONIH1_RS11180	COG3134	Outer membrane lipoprotein
KONIH1_RS11190	COG1309	transcriptional regulator
KONIH1_RS11200	COG1388	LysM domain
KONIH1_RS11200	COG1376	ErfK ybiS ycfS ynhG family protein
KONIH1_RS11205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KONIH1_RS11210	COG4591	ABC-type transport system involved in lipoprotein release permease component
KONIH1_RS11215	COG1136	(ABC) transporter
KONIH1_RS11220	COG4591	ABC-type transport system involved in lipoprotein release permease component
KONIH1_RS11230	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KONIH1_RS11235	COG2390	Transcriptional regulator
KONIH1_RS11250	COG3395	kinase activity
KONIH1_RS11265	COG0698	ribose 5-phosphate isomerase
KONIH1_RS11270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KONIH1_RS11275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KONIH1_RS11290	COG1177	transmembrane transport
KONIH1_RS11310	COG2850	peptidyl-arginine hydroxylation
KONIH1_RS11315	COG2205	protein histidine kinase activity
KONIH1_RS11320	COG0745	RESPONSE REGULATOR receiver
KONIH1_RS11330	COG2814	Major facilitator Superfamily
KONIH1_RS11335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KONIH1_RS11355	COG1187	pseudouridine synthase activity
KONIH1_RS11360	COG0538	isocitrate dehydrogenase activity
KONIH1_RS11385	COG0583	DNA-binding transcription factor activity
KONIH1_RS11390	COG3706	GGDEF domain
KONIH1_RS11395	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KONIH1_RS11405	COG1120	ATPase activity
KONIH1_RS11410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KONIH1_RS11415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KONIH1_RS11420	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KONIH1_RS11425	COG4772	TonB-dependent receptor
KONIH1_RS11430	COG3712	iron ion homeostasis
KONIH1_RS11435	COG1595	DNA-templated transcription, initiation
KONIH1_RS11440	COG2226	methyltransferase
KONIH1_RS11445	COG1560	Kdo2-lipid A biosynthetic process
KONIH1_RS11455	COG3182	Iron-regulated membrane protein
KONIH1_RS11465	COG2203	Gaf domain
KONIH1_RS11465	COG2199	diguanylate cyclase activity
KONIH1_RS11470	COG3042	response to heat
KONIH1_RS11475	COG3189	MarR family transcriptional regulator
KONIH1_RS11480	COG1683	Conserved Protein
KONIH1_RS11485	COG0504	CTP synthase activity
KONIH1_RS11490	COG2807	transmembrane transport
KONIH1_RS11495	COG2207	Transcriptional regulator
KONIH1_RS11505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KONIH1_RS11510	COG2199	diguanylate cyclase activity
KONIH1_RS11520	COG0859	PFAM glycosyl transferase family 9
KONIH1_RS11530	COG2766	serine protein kinase
KONIH1_RS11535	COG3713	MltA-interacting MipA family protein
KONIH1_RS11540	COG0656	L-ascorbic acid biosynthetic process
KONIH1_RS11560	COG3139	Protein of unknown function (DUF1315)
KONIH1_RS11575	COG1063	alcohol dehydrogenase
KONIH1_RS11580	COG2271	Major facilitator Superfamily
KONIH1_RS11585	COG1063	alcohol dehydrogenase
KONIH1_RS11590	COG0191	fructose-bisphosphate aldolase activity
KONIH1_RS11595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KONIH1_RS11600	COG0667	Aldo Keto reductase
KONIH1_RS11605	COG1349	DNA-binding transcription factor activity
KONIH1_RS11610	COG2814	Major facilitator Superfamily
KONIH1_RS11615	COG1335	isochorismatase
KONIH1_RS11620	COG0252	asparaginase activity
KONIH1_RS11625	COG0616	signal peptide processing
KONIH1_RS11630	COG0778	Nitroreductase
KONIH1_RS11640	COG0709	Synthesizes selenophosphate from selenide and ATP
KONIH1_RS11645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KONIH1_RS11655	COG0494	nUDIX hydrolase
KONIH1_RS11660	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KONIH1_RS11665	COG2897	thiosulfate sulfurtransferase activity
KONIH1_RS11670	COG4136	ATPase activity
KONIH1_RS11675	COG4135	transport system, permease component
KONIH1_RS11680	COG4134	Bacterial extracellular solute-binding protein
KONIH1_RS11685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KONIH1_RS11690	COG0398	Pfam SNARE associated Golgi protein
KONIH1_RS11695	COG0398	Pfam SNARE associated Golgi protein
KONIH1_RS11700	COG0708	Exodeoxyribonuclease III
KONIH1_RS11710	COG3138	arginine N-succinyltransferase
KONIH1_RS11730	COG3678	ATP-independent chaperone mediated protein folding
KONIH1_RS11735	COG1704	LemA family
KONIH1_RS11740	COG4907	membrane protein (DUF2207)
KONIH1_RS11745	COG0322	excinuclease ABC activity
KONIH1_RS11755	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KONIH1_RS11760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KONIH1_RS11765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KONIH1_RS11770	COG1447	Phosphotransferase system cellobiose-specific component IIA
KONIH1_RS11775	COG1917	Cupin 2, conserved barrel domain protein
KONIH1_RS11775	COG2169	Transcriptional regulator
KONIH1_RS11780	COG1486	melibiose metabolic process
KONIH1_RS11790	COG0753	catalase activity
KONIH1_RS11800	COG1823	symporter activity
KONIH1_RS11805	COG1988	membrane-bound metal-dependent
KONIH1_RS11810	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS11815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KONIH1_RS11835	COG0038	chloride channel
KONIH1_RS11850	COG3047	cAMP biosynthetic process
KONIH1_RS11875	COG0583	DNA-binding transcription factor activity
KONIH1_RS11880	COG1063	alcohol dehydrogenase
KONIH1_RS11900	COG0135	phosphoribosylanthranilate isomerase activity
KONIH1_RS11900	COG0134	indole-3-glycerol-phosphate synthase activity
KONIH1_RS11905	COG0512	Glutamine amidotransferase of anthranilate synthase
KONIH1_RS11905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KONIH1_RS11910	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KONIH1_RS11920	COG0009	L-threonylcarbamoyladenylate synthase
KONIH1_RS11925	COG1187	pseudouridine synthase activity
KONIH1_RS11930	COG2211	Major facilitator Superfamily
KONIH1_RS11935	COG1472	Belongs to the glycosyl hydrolase 3 family
KONIH1_RS11940	COG2207	Transcriptional regulator
KONIH1_RS11950	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS11955	COG0616	signal peptide processing
KONIH1_RS11975	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KONIH1_RS11985	COG0671	phosphoesterase, PA-phosphatase related
KONIH1_RS11990	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
KONIH1_RS11995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KONIH1_RS12005	COG0023	Translation Initiation Factor
KONIH1_RS12015	COG1349	DNA-binding transcription factor activity
KONIH1_RS12030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KONIH1_RS12030	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KONIH1_RS12035	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KONIH1_RS12040	COG4172	Belongs to the ABC transporter superfamily
KONIH1_RS12050	COG4171	peptide transport system, permease
KONIH1_RS12060	COG4166	transmembrane transport
KONIH1_RS12075	COG1473	amidohydrolase
KONIH1_RS12085	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KONIH1_RS12090	COG1842	Phage shock protein A
KONIH1_RS12100	COG1983	PspC domain protein
KONIH1_RS12110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KONIH1_RS12115	COG3106	COG3106 Predicted ATPase
KONIH1_RS12130	COG3180	Ammonia monooxygenase
KONIH1_RS12135	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KONIH1_RS12140	COG4948	Mandelate Racemase Muconate Lactonizing
KONIH1_RS12145	COG2866	Carboxypeptidase
KONIH1_RS12150	COG4166	transmembrane transport
KONIH1_RS12165	COG2011	ABC-type metal ion transport system permease component
KONIH1_RS12170	COG1464	Belongs to the NlpA lipoprotein family
KONIH1_RS12175	COG2814	Major facilitator Superfamily
KONIH1_RS12190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KONIH1_RS12205	COG2188	Transcriptional regulator
KONIH1_RS12210	COG1605	Chorismate mutase
KONIH1_RS12215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS12220	COG1126	abc transporter atp-binding protein
KONIH1_RS12225	COG0765	amino acid transport
KONIH1_RS12235	COG1045	serine acetyltransferase
KONIH1_RS12240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KONIH1_RS12260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KONIH1_RS12265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KONIH1_RS12275	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KONIH1_RS12285	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KONIH1_RS12290	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KONIH1_RS12305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KONIH1_RS12315	COG0693	protein deglycase activity
KONIH1_RS12320	COG0582	viral genome integration into host DNA
KONIH1_RS12380	COG4626	Terminase
KONIH1_RS12380	COG1802	Transcriptional regulator
KONIH1_RS12500	COG4386	tail sheath protein
KONIH1_RS12515	COG0741	lytic transglycosylase activity
KONIH1_RS12680	COG3507	Belongs to the glycosyl hydrolase 43 family
KONIH1_RS12685	COG2211	Major facilitator Superfamily
KONIH1_RS12690	COG4580	involved in the transport of maltose and maltodextrins
KONIH1_RS12695	COG3272	Protein of unknown function (DUF1722)
KONIH1_RS12705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KONIH1_RS12720	COG0300	oxidoreductase activity
KONIH1_RS12730	COG0789	Transcriptional regulator
KONIH1_RS12755	COG0583	DNA-binding transcription factor activity
KONIH1_RS12765	COG0300	oxidoreductase activity
KONIH1_RS12785	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KONIH1_RS12785	COG2885	chlorophyll binding
KONIH1_RS12790	COG3477	response to acidic pH
KONIH1_RS12810	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KONIH1_RS12815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KONIH1_RS12820	COG0673	inositol 2-dehydrogenase activity
KONIH1_RS12825	COG1349	DNA-binding transcription factor activity
KONIH1_RS12840	COG0513	Belongs to the DEAD box helicase family
KONIH1_RS12865	COG0589	response to stress
KONIH1_RS12875	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KONIH1_RS12880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KONIH1_RS12880	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KONIH1_RS12880	COG0674	pyruvate-flavodoxin oxidoreductase activity
KONIH1_RS12880	COG1013	pyruvate-flavodoxin oxidoreductase activity
KONIH1_RS12955	COG3042	response to heat
KONIH1_RS12960	COG3187	Heat shock protein
KONIH1_RS12965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KONIH1_RS12970	COG0586	Pfam SNARE associated Golgi protein
KONIH1_RS12975	COG2911	Protein conserved in bacteria
KONIH1_RS12985	COG3784	Protein of unknown function (DUF1318)
KONIH1_RS12990	COG2207	Transcriptional regulator
KONIH1_RS12995	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS13010	COG5285	phytanoyl-CoA dioxygenase
KONIH1_RS13015	COG1126	abc transporter atp-binding protein
KONIH1_RS13020	COG0583	DNA-binding transcription factor activity
KONIH1_RS13025	COG2072	flavoprotein involved in K transport
KONIH1_RS13040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KONIH1_RS13055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KONIH1_RS13080	COG1566	PFAM secretion protein HlyD family protein
KONIH1_RS13095	COG2207	Transcriptional regulator
KONIH1_RS13100	COG3708	Transcriptional regulator
KONIH1_RS13100	COG2207	Transcriptional regulator
KONIH1_RS13105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KONIH1_RS13120	COG0406	alpha-ribazole phosphatase activity
KONIH1_RS13125	COG2378	regulation of single-species biofilm formation
KONIH1_RS13130	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS13140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KONIH1_RS13145	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KONIH1_RS13165	COG0583	DNA-binding transcription factor activity
KONIH1_RS13190	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS13190	COG2030	dehydratase
KONIH1_RS13195	COG3396	Phenylacetate-CoA oxygenase
KONIH1_RS13200	COG3460	Phenylacetate-CoA oxygenase
KONIH1_RS13205	COG3396	Phenylacetate-CoA oxygenase
KONIH1_RS13210	COG2151	metal-sulfur cluster biosynthetic enzyme
KONIH1_RS13215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KONIH1_RS13220	COG1024	Enoyl-CoA hydratase
KONIH1_RS13225	COG1024	Enoyl-CoA hydratase
KONIH1_RS13230	COG1250	3-hydroxyacyl-CoA dehydrogenase
KONIH1_RS13235	COG2050	protein possibly involved in aromatic compounds catabolism
KONIH1_RS13240	COG0183	Belongs to the thiolase family
KONIH1_RS13245	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KONIH1_RS13250	COG3327	negative regulation of DNA-templated transcription, initiation
KONIH1_RS13255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KONIH1_RS13270	COG1643	Atp-dependent helicase
KONIH1_RS13275	COG4122	O-methyltransferase activity
KONIH1_RS13280	COG1538	Outer membrane efflux protein
KONIH1_RS13300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KONIH1_RS13305	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KONIH1_RS13310	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS13315	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KONIH1_RS13320	COG0456	acetyltransferase
KONIH1_RS13325	COG0583	DNA-binding transcription factor activity
KONIH1_RS13330	COG3706	GGDEF domain
KONIH1_RS13350	COG3038	cytochrome b561
KONIH1_RS13375	COG0583	DNA-binding transcription factor activity
KONIH1_RS13380	COG3485	protocatechuate 3,4-dioxygenase
KONIH1_RS13385	COG3485	protocatechuate 3,4-dioxygenase
KONIH1_RS13390	COG5383	Protein conserved in bacteria
KONIH1_RS13395	COG2272	Belongs to the type-B carboxylesterase lipase family
KONIH1_RS13405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KONIH1_RS13410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KONIH1_RS13415	COG1275	C4-dicarboxylate transporter malic acid transport protein
KONIH1_RS13420	COG0500	methyltransferase
KONIH1_RS13425	COG2195	Cleaves the N-terminal amino acid of tripeptides
KONIH1_RS13430	COG0747	negative chemotaxis
KONIH1_RS13435	COG3039	Transposase
KONIH1_RS13445	COG0697	spore germination
KONIH1_RS13450	COG2207	Transcriptional regulator
KONIH1_RS13455	COG3135	benzoate transporter
KONIH1_RS13460	COG1396	sequence-specific DNA binding
KONIH1_RS13465	COG0826	peptidase U32
KONIH1_RS13475	COG1294	oxidase, subunit
KONIH1_RS13480	COG1271	oxidase subunit
KONIH1_RS13485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KONIH1_RS13495	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KONIH1_RS13500	COG3842	ATPase activity
KONIH1_RS13505	COG1176	ABC-type spermidine putrescine transport system, permease component I
KONIH1_RS13510	COG1177	transmembrane transport
KONIH1_RS13515	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS13525	COG0596	Alpha beta hydrolase
KONIH1_RS13530	COG4677	pectinesterase activity
KONIH1_RS13535	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS13540	COG0747	negative chemotaxis
KONIH1_RS13550	COG3238	Protein conserved in bacteria
KONIH1_RS13555	COG1247	-acetyltransferase
KONIH1_RS13570	COG2130	NADP-dependent
KONIH1_RS13580	COG3691	Protein conserved in bacteria
KONIH1_RS13585	COG4772	TonB-dependent receptor
KONIH1_RS13610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KONIH1_RS13615	COG1473	amidohydrolase
KONIH1_RS13620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KONIH1_RS13625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS13640	COG1126	abc transporter atp-binding protein
KONIH1_RS13650	COG2271	Major facilitator Superfamily
KONIH1_RS13660	COG1609	Transcriptional regulator
KONIH1_RS13665	COG0625	glutathione transferase activity
KONIH1_RS13690	COG2211	Major facilitator Superfamily
KONIH1_RS13700	COG4977	sequence-specific DNA binding
KONIH1_RS13705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KONIH1_RS13710	COG3842	ATPase activity
KONIH1_RS13715	COG1840	ABC-type Fe3 transport system, periplasmic component
KONIH1_RS13720	COG1178	ABC-type Fe3 transport system permease component
KONIH1_RS13725	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KONIH1_RS13730	COG2181	nitrate reductase activity
KONIH1_RS13735	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KONIH1_RS13740	COG1140	nitrate reductase beta subunit
KONIH1_RS13745	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KONIH1_RS13765	COG0697	spore germination
KONIH1_RS13775	COG3383	formate dehydrogenase (NAD+) activity
KONIH1_RS13775	COG0243	molybdopterin cofactor binding
KONIH1_RS13780	COG3383	formate dehydrogenase (NAD+) activity
KONIH1_RS13780	COG0243	molybdopterin cofactor binding
KONIH1_RS13785	COG0437	4 iron, 4 sulfur cluster binding
KONIH1_RS13790	COG2864	formate dehydrogenase
KONIH1_RS13800	COG2814	Major facilitator Superfamily
KONIH1_RS13810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KONIH1_RS13820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KONIH1_RS13840	COG1064	alcohol dehydrogenase
KONIH1_RS13850	COG1064	alcohol dehydrogenase
KONIH1_RS13860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KONIH1_RS13885	COG0488	(ABC) transporter
KONIH1_RS13915	COG1764	response to oxidative stress
KONIH1_RS13930	COG3781	membrane
KONIH1_RS13935	COG0243	molybdopterin cofactor binding
KONIH1_RS13940	COG1280	lysine exporter protein (LysE YggA)
KONIH1_RS13950	COG0583	DNA-binding transcription factor activity
KONIH1_RS13955	COG0583	DNA-binding transcription factor activity
KONIH1_RS13965	COG2271	Major facilitator Superfamily
KONIH1_RS14005	COG1280	lysine exporter protein (LysE YggA)
KONIH1_RS14030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KONIH1_RS14030	COG1116	anion transmembrane transporter activity
KONIH1_RS14045	COG0439	Biotin carboxylase
KONIH1_RS14060	COG0519	Catalyzes the synthesis of GMP from XMP
KONIH1_RS14060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KONIH1_RS14075	COG0076	glutamate decarboxylase activity
KONIH1_RS14080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KONIH1_RS14085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KONIH1_RS14090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KONIH1_RS14095	COG1116	anion transmembrane transporter activity
KONIH1_RS14100	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KONIH1_RS14105	COG0673	inositol 2-dehydrogenase activity
KONIH1_RS14110	COG1082	Xylose isomerase domain protein TIM barrel
KONIH1_RS14115	COG1609	Transcriptional regulator
KONIH1_RS14145	COG1649	PFAM Uncharacterised BCR, COG1649
KONIH1_RS14150	COG2771	luxR family
KONIH1_RS14150	COG2200	EAL domain
KONIH1_RS14155	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KONIH1_RS14175	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS14185	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KONIH1_RS14200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KONIH1_RS14205	COG0508	dehydrogenase complex catalyzes the overall conversion of
KONIH1_RS14210	COG0022	dehydrogenase e1 component
KONIH1_RS14215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KONIH1_RS14300	COG1760	l-serine dehydratase
KONIH1_RS14305	COG0814	amino acid
KONIH1_RS14330	COG1169	isochorismate synthase
KONIH1_RS14335	COG2814	Major facilitator Superfamily
KONIH1_RS14340	COG1132	(ABC) transporter
KONIH1_RS14345	COG1132	(ABC) transporter
KONIH1_RS14345	COG2375	cellular response to nickel ion
KONIH1_RS14355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KONIH1_RS14355	COG2226	methyltransferase
KONIH1_RS14355	COG3433	isochorismatase activity
KONIH1_RS14375	COG1021	2,3-dihydroxybenzoate-AMP ligase
KONIH1_RS14380	COG4771	TonB-dependent receptor
KONIH1_RS14385	COG1652	LysM domain
KONIH1_RS14415	COG1609	Transcriptional regulator
KONIH1_RS14425	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS14440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KONIH1_RS14450	COG4771	TonB-dependent receptor
KONIH1_RS14455	COG3391	amine dehydrogenase activity
KONIH1_RS14485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KONIH1_RS14530	COG4821	SIS domain
KONIH1_RS14545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS14585	COG2841	Protein conserved in bacteria
KONIH1_RS14610	COG0583	DNA-binding transcription factor activity
KONIH1_RS14615	COG0412	Dienelactone hydrolase
KONIH1_RS14630	COG0693	protein deglycase activity
KONIH1_RS14640	COG1609	Transcriptional regulator
KONIH1_RS14650	COG1129	ABC transporter
KONIH1_RS14655	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS14680	COG1070	Carbohydrate kinase
KONIH1_RS14685	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS14690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KONIH1_RS14695	COG3775	system Galactitol-specific IIC component
KONIH1_RS14715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KONIH1_RS14720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KONIH1_RS14725	COG1120	ATPase activity
KONIH1_RS14740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KONIH1_RS14745	COG1446	asparaginase
KONIH1_RS14750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KONIH1_RS14760	COG2207	Transcriptional regulator
KONIH1_RS14765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KONIH1_RS14785	COG0765	amino acid transport
KONIH1_RS14790	COG0765	amino acid transport
KONIH1_RS14795	COG1126	abc transporter atp-binding protein
KONIH1_RS14810	COG4628	conserved protein (DUF2132)
KONIH1_RS14830	COG2011	ABC-type metal ion transport system permease component
KONIH1_RS14845	COG0477	Major facilitator Superfamily
KONIH1_RS14880	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KONIH1_RS14885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KONIH1_RS14930	COG2199	diguanylate cyclase activity
KONIH1_RS14945	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS14950	COG0583	DNA-binding transcription factor activity
KONIH1_RS14960	COG0039	L-malate dehydrogenase activity
KONIH1_RS15000	COG0697	spore germination
KONIH1_RS15005	COG2814	Major facilitator Superfamily
KONIH1_RS15025	COG1129	ABC transporter
KONIH1_RS15045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KONIH1_RS15085	COG2200	EAL domain
KONIH1_RS15105	COG2223	nitrite transmembrane transporter activity
KONIH1_RS15110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KONIH1_RS15135	COG3122	Protein conserved in bacteria
KONIH1_RS15160	COG0339	signal peptide processing
KONIH1_RS15165	COG4221	oxidoreductase activity
KONIH1_RS15170	COG1802	Transcriptional regulator
KONIH1_RS15175	COG0589	response to stress
KONIH1_RS15180	COG0246	Mannitol dehydrogenase
KONIH1_RS15185	COG0477	Major facilitator Superfamily
KONIH1_RS15190	COG1063	alcohol dehydrogenase
KONIH1_RS15195	COG4948	Mandelate Racemase Muconate Lactonizing
KONIH1_RS15210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KONIH1_RS15225	COG0243	molybdopterin cofactor binding
KONIH1_RS15230	COG0437	4 iron, 4 sulfur cluster binding
KONIH1_RS15235	COG3302	dmso reductase anchor subunit
KONIH1_RS15240	COG3381	protein complex oligomerization
KONIH1_RS15250	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KONIH1_RS15255	COG1940	carbohydrate kinase activity
KONIH1_RS15260	COG0583	DNA-binding transcription factor activity
KONIH1_RS15265	COG2814	Major facilitator Superfamily
KONIH1_RS15270	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KONIH1_RS15280	COG3591	Belongs to the peptidase S1B family
KONIH1_RS15300	COG0628	permease
KONIH1_RS15330	COG0679	Auxin Efflux Carrier
KONIH1_RS15340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KONIH1_RS15355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KONIH1_RS15360	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS15370	COG3290	protein histidine kinase activity
KONIH1_RS15375	COG4565	transcriptional regulatory protein
KONIH1_RS15395	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KONIH1_RS15395	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KONIH1_RS15400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KONIH1_RS15405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KONIH1_RS15415	COG0183	Belongs to the thiolase family
KONIH1_RS15420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KONIH1_RS15430	COG1414	Transcriptional regulator
KONIH1_RS15435	COG2840	Smr protein MutS2
KONIH1_RS15440	COG0583	DNA-binding transcription factor activity
KONIH1_RS15450	COG1473	amidohydrolase
KONIH1_RS15455	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KONIH1_RS15460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KONIH1_RS15465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KONIH1_RS15470	COG0589	response to stress
KONIH1_RS15480	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KONIH1_RS15485	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KONIH1_RS15495	COG0531	amino acid
KONIH1_RS15505	COG3136	membrane protein required for alginate biosynthesis
KONIH1_RS15515	COG0745	RESPONSE REGULATOR receiver
KONIH1_RS15525	COG0386	Belongs to the glutathione peroxidase family
KONIH1_RS15535	COG2205	protein histidine kinase activity
KONIH1_RS15545	COG0114	fumarate hydratase activity
KONIH1_RS15550	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KONIH1_RS15550	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KONIH1_RS15555	COG1482	cell wall glycoprotein biosynthetic process
KONIH1_RS15560	COG5339	Protein conserved in bacteria
KONIH1_RS15565	COG1609	Transcriptional regulator
KONIH1_RS15570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS15570	COG1263	PTS System
KONIH1_RS15575	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KONIH1_RS15585	COG2391	methyltransferase activity
KONIH1_RS15590	COG0425	Belongs to the sulfur carrier protein TusA family
KONIH1_RS15605	COG0673	inositol 2-dehydrogenase activity
KONIH1_RS15615	COG2723	6-phospho-beta-galactosidase activity
KONIH1_RS15650	COG4659	FMN binding
KONIH1_RS15660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KONIH1_RS15670	COG0625	glutathione transferase activity
KONIH1_RS15690	COG3895	Periplasmic Protein
KONIH1_RS15705	COG3706	GGDEF domain
KONIH1_RS15720	COG1566	PFAM secretion protein HlyD family protein
KONIH1_RS15725	COG1289	transmembrane transporter activity
KONIH1_RS15735	COG4989	oxidoreductase activity
KONIH1_RS15740	COG3313	Fe-S protein
KONIH1_RS15745	COG1309	transcriptional regulator
KONIH1_RS15750	COG1902	pentaerythritol trinitrate reductase activity
KONIH1_RS15755	COG0346	lactoylglutathione lyase activity
KONIH1_RS15765	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KONIH1_RS15770	COG0791	NLP P60 protein
KONIH1_RS15780	COG2814	Major facilitator Superfamily
KONIH1_RS15790	COG0583	DNA-binding transcription factor activity
KONIH1_RS15795	COG2814	Major facilitator Superfamily
KONIH1_RS15800	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KONIH1_RS15805	COG0307	riboflavin synthase, alpha
KONIH1_RS15830	COG3729	General stress protein
KONIH1_RS15835	COG3685	Protein conserved in bacteria
KONIH1_RS15840	COG3685	Protein conserved in bacteria
KONIH1_RS15845	COG3546	catalase activity
KONIH1_RS15855	COG1294	oxidase, subunit
KONIH1_RS15870	COG1546	Belongs to the CinA family
KONIH1_RS15875	COG2323	membrane
KONIH1_RS15890	COG4529	Protein conserved in bacteria
KONIH1_RS15895	COG3111	PFAM Bacterial OB fold (BOF) protein
KONIH1_RS15900	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS15905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KONIH1_RS15920	COG1349	DNA-binding transcription factor activity
KONIH1_RS15925	COG0346	lactoylglutathione lyase activity
KONIH1_RS15935	COG4166	transmembrane transport
KONIH1_RS15950	COG0444	Belongs to the ABC transporter superfamily
KONIH1_RS15960	COG4993	Dehydrogenase
KONIH1_RS15965	COG0582	viral genome integration into host DNA
KONIH1_RS15975	COG3121	Chaperone
KONIH1_RS15990	COG3539	Fimbrial protein
KONIH1_RS15995	COG0582	viral genome integration into host DNA
KONIH1_RS16015	COG1278	Cold shock
KONIH1_RS16040	COG3842	ATPase activity
KONIH1_RS16045	COG1175	transmembrane transport
KONIH1_RS16140	COG2885	chlorophyll binding
KONIH1_RS16165	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KONIH1_RS16170	COG3383	formate dehydrogenase (NAD+) activity
KONIH1_RS16175	COG1473	amidohydrolase
KONIH1_RS16185	COG1126	abc transporter atp-binding protein
KONIH1_RS16190	COG0765	amino acid transport
KONIH1_RS16210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KONIH1_RS16215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KONIH1_RS16220	COG1120	ATPase activity
KONIH1_RS16225	COG4774	siderophore transport
KONIH1_RS16230	COG1116	anion transmembrane transporter activity
KONIH1_RS16235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KONIH1_RS16250	COG1960	acyl-CoA dehydrogenase activity
KONIH1_RS16255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KONIH1_RS16285	COG2814	Major facilitator Superfamily
KONIH1_RS16320	COG1414	Transcriptional regulator
KONIH1_RS16325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KONIH1_RS16330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KONIH1_RS16335	COG1120	ATPase activity
KONIH1_RS16345	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KONIH1_RS16350	COG2271	Major facilitator Superfamily
KONIH1_RS16355	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KONIH1_RS16355	COG1082	Xylose isomerase domain protein TIM barrel
KONIH1_RS16380	COG1376	ErfK ybiS ycfS ynhG family protein
KONIH1_RS16395	COG0719	Fe-S assembly protein
KONIH1_RS16400	COG0396	ATPase activity
KONIH1_RS16405	COG0719	Fe-S assembly protein
KONIH1_RS16410	COG0316	Belongs to the HesB IscA family
KONIH1_RS16415	COG3539	Fimbrial protein
KONIH1_RS16430	COG3121	Chaperone
KONIH1_RS16445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KONIH1_RS16450	COG2261	transglycosylase associated protein
KONIH1_RS16455	COG3039	Transposase
KONIH1_RS16460	COG2050	protein possibly involved in aromatic compounds catabolism
KONIH1_RS16465	COG0277	FAD linked oxidase domain protein
KONIH1_RS16465	COG0247	lactate metabolic process
KONIH1_RS16470	COG0628	permease
KONIH1_RS16475	COG0574	Belongs to the PEP-utilizing enzyme family
KONIH1_RS16475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KONIH1_RS16485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KONIH1_RS16490	COG4256	Hemin uptake protein
KONIH1_RS16500	COG0791	NLP P60 protein
KONIH1_RS16510	COG0386	Belongs to the glutathione peroxidase family
KONIH1_RS16530	COG0072	phenylalanine-tRNA ligase activity
KONIH1_RS16530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KONIH1_RS16540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KONIH1_RS16565	COG3137	Salt-induced outer membrane protein
KONIH1_RS16570	COG1105	Belongs to the carbohydrate kinase PfkB family
KONIH1_RS16580	COG3001	Fructosamine kinase
KONIH1_RS16590	COG2350	Protein conserved in bacteria
KONIH1_RS16595	COG1902	pentaerythritol trinitrate reductase activity
KONIH1_RS16615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KONIH1_RS16625	COG0444	Belongs to the ABC transporter superfamily
KONIH1_RS16630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KONIH1_RS16635	COG0601	transmembrane transport
KONIH1_RS16645	COG2095	MarC family integral membrane protein
KONIH1_RS16650	COG1454	alcohol dehydrogenase
KONIH1_RS16650	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS16665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KONIH1_RS16670	COG0745	RESPONSE REGULATOR receiver
KONIH1_RS16675	COG1752	Esterase of the alpha-beta hydrolase superfamily
KONIH1_RS16685	COG0788	formyltetrahydrofolate deformylase activity
KONIH1_RS16700	COG2181	nitrate reductase activity
KONIH1_RS16705	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KONIH1_RS16710	COG1140	nitrate reductase beta subunit
KONIH1_RS16715	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KONIH1_RS16720	COG2223	nitrite transmembrane transporter activity
KONIH1_RS16725	COG3850	Histidine kinase
KONIH1_RS16730	COG2197	response regulator
KONIH1_RS16735	COG4932	domain protein
KONIH1_RS16740	COG0243	molybdopterin cofactor binding
KONIH1_RS16745	COG2146	nitrite reductase [NAD(P)H] activity
KONIH1_RS16745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KONIH1_RS16750	COG1116	anion transmembrane transporter activity
KONIH1_RS16760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KONIH1_RS16765	COG3707	response regulator
KONIH1_RS16770	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KONIH1_RS16780	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KONIH1_RS16785	COG4572	Cation transport regulator
KONIH1_RS16790	COG0387	Pfam Sodium calcium exchanger
KONIH1_RS16810	COG2890	protein-(glutamine-N5) methyltransferase activity
KONIH1_RS16840	COG0659	secondary active sulfate transmembrane transporter activity
KONIH1_RS16860	COG0012	GTP binding
KONIH1_RS16865	COG0582	viral genome integration into host DNA
KONIH1_RS16875	COG3829	transcription factor binding
KONIH1_RS16880	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KONIH1_RS16885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KONIH1_RS16890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KONIH1_RS16900	COG0549	Belongs to the carbamate kinase family
KONIH1_RS16905	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KONIH1_RS16905	COG3608	succinylglutamate desuccinylase aspartoacylase
KONIH1_RS16910	COG0493	'glutamate synthase
KONIH1_RS16910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KONIH1_RS16915	COG0402	S-adenosylhomocysteine deaminase activity
KONIH1_RS16920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KONIH1_RS16925	COG0493	'glutamate synthase
KONIH1_RS16925	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KONIH1_RS16930	COG2233	PERMEase
KONIH1_RS16935	COG3383	formate dehydrogenase (NAD+) activity
KONIH1_RS16940	COG3383	formate dehydrogenase (NAD+) activity
KONIH1_RS16945	COG2068	MobA-Related Protein
KONIH1_RS16960	COG2814	Major facilitator Superfamily
KONIH1_RS16965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS16965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS16970	COG2351	hydroxyisourate hydrolase activity
KONIH1_RS16990	COG0583	DNA-binding transcription factor activity
KONIH1_RS16995	COG0564	pseudouridine synthase activity
KONIH1_RS17010	COG1174	glycine betaine transport
KONIH1_RS17020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KONIH1_RS17035	COG2814	Major facilitator Superfamily
KONIH1_RS17060	COG2308	Evidence 4 Homologs of previously reported genes of
KONIH1_RS17070	COG1472	Belongs to the glycosyl hydrolase 3 family
KONIH1_RS17080	COG2211	Major facilitator Superfamily
KONIH1_RS17095	COG1619	proteins homologs of microcin C7 resistance protein MccF
KONIH1_RS17240	COG4695	Portal protein
KONIH1_RS17320	COG4974	Belongs to the 'phage' integrase family
KONIH1_RS17345	COG2719	SpoVR family
KONIH1_RS17375	COG0179	Fumarylacetoacetate (FAA) hydrolase
KONIH1_RS17390	COG2894	cell division
KONIH1_RS17400	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KONIH1_RS17410	COG3065	identical protein binding
KONIH1_RS17415	COG1214	PFAM Peptidase M22, glycoprotease
KONIH1_RS17420	COG1199	ATP-dependent helicase activity
KONIH1_RS17425	COG0251	oxidation-reduction process
KONIH1_RS17435	COG3842	ATPase activity
KONIH1_RS17440	COG0395	ABC-type sugar transport system, permease component
KONIH1_RS17445	COG1175	transmembrane transport
KONIH1_RS17450	COG1653	transport
KONIH1_RS17480	COG1760	l-serine dehydratase
KONIH1_RS17485	COG2200	EAL domain
KONIH1_RS17490	COG1253	flavin adenine dinucleotide binding
KONIH1_RS17495	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS17495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS17500	COG3715	PTS system
KONIH1_RS17505	COG3716	PTS system mannose fructose sorbose family IID component
KONIH1_RS17525	COG2226	methyltransferase
KONIH1_RS17530	COG0768	penicillin binding
KONIH1_RS17555	COG1414	Transcriptional regulator
KONIH1_RS17560	COG2814	Major facilitator Superfamily
KONIH1_RS17580	COG1956	GAF domain-containing protein
KONIH1_RS17585	COG2995	paraquat-inducible protein a
KONIH1_RS17590	COG3008	intermembrane lipid transfer
KONIH1_RS17615	COG2990	Protein conserved in bacteria
KONIH1_RS17650	COG1276	copper resistance
KONIH1_RS17655	COG2372	response to copper ion
KONIH1_RS17665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KONIH1_RS17670	COG1770	oligopeptidase
KONIH1_RS17675	COG2979	Protein of unknown function (DUF533)
KONIH1_RS17680	COG3141	response to X-ray
KONIH1_RS17690	COG0800	Aldolase
KONIH1_RS17695	COG0129	dihydroxy-acid dehydratase activity
KONIH1_RS17700	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KONIH1_RS17705	COG1737	Transcriptional regulator
KONIH1_RS17715	COG3493	citrate carrier protein
KONIH1_RS17720	COG0679	Auxin Efflux Carrier
KONIH1_RS17725	COG0281	malic enzyme
KONIH1_RS17735	COG1560	Kdo2-lipid A biosynthetic process
KONIH1_RS17740	COG0739	heme binding
KONIH1_RS17745	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KONIH1_RS17755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KONIH1_RS17775	COG0217	transcriptional regulatory protein
KONIH1_RS17780	COG0494	nUDIX hydrolase
KONIH1_RS17790	COG1335	isochorismatase
KONIH1_RS17795	COG1801	Protein of unknown function DUF72
KONIH1_RS17815	COG3039	Transposase
KONIH1_RS17850	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KONIH1_RS17855	COG1801	Protein of unknown function DUF72
KONIH1_RS17860	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KONIH1_RS17880	COG3102	Protein conserved in bacteria
KONIH1_RS17890	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KONIH1_RS17915	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS17925	COG1879	ABC-type sugar transport system periplasmic component
KONIH1_RS17935	COG1528	Iron-storage protein
KONIH1_RS17950	COG0477	Major facilitator Superfamily
KONIH1_RS17960	COG1528	Iron-storage protein
KONIH1_RS17970	COG0814	amino acid
KONIH1_RS17975	COG3012	SEC-C Motif Domain Protein
KONIH1_RS17975	COG3318	Belongs to the UPF0149 family
KONIH1_RS17980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KONIH1_RS18065	COG0741	lytic transglycosylase activity
KONIH1_RS18190	COG0305	Participates in initiation and elongation during chromosome replication
KONIH1_RS18275	COG2197	response regulator
KONIH1_RS18285	COG2197	response regulator
KONIH1_RS18290	COG1126	abc transporter atp-binding protein
KONIH1_RS18295	COG0765	amino acid transport
KONIH1_RS18305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS18310	COG0366	Alpha amylase catalytic
KONIH1_RS18345	COG5475	Uncharacterized small protein (DUF2158)
KONIH1_RS18350	COG2354	Protein conserved in bacteria
KONIH1_RS18355	COG0697	spore germination
KONIH1_RS18360	COG3727	T/G mismatch-specific endonuclease activity
KONIH1_RS18365	COG0270	DNA (cytosine-5-)-methyltransferase activity
KONIH1_RS18370	COG1418	mRNA catabolic process
KONIH1_RS18380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KONIH1_RS18390	COG0463	Glycosyl transferase, family 2
KONIH1_RS18420	COG0251	oxidation-reduction process
KONIH1_RS18440	COG2819	hydrolase of the alpha beta superfamily
KONIH1_RS18450	COG0589	response to stress
KONIH1_RS18460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KONIH1_RS18490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KONIH1_RS18500	COG0534	Mate efflux family protein
KONIH1_RS18525	COG0583	DNA-binding transcription factor activity
KONIH1_RS18530	COG0667	Aldo Keto reductase
KONIH1_RS18545	COG1376	ErfK ybiS ycfS ynhG family protein
KONIH1_RS18585	COG3539	Fimbrial protein
KONIH1_RS18590	COG3121	Chaperone
KONIH1_RS18595	COG3188	usher protein
KONIH1_RS18600	COG3539	Fimbrial protein
KONIH1_RS18605	COG3539	Fimbrial protein
KONIH1_RS18610	COG3539	Fimbrial protein
KONIH1_RS18625	COG1263	PTS System
KONIH1_RS18625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS18630	COG2188	Transcriptional regulator
KONIH1_RS18640	COG3615	Tellurite resistance protein tehB
KONIH1_RS18645	COG3300	MHYT domain
KONIH1_RS18645	COG5001	Diguanylate cyclase
KONIH1_RS18655	COG0477	Major facilitator Superfamily
KONIH1_RS18660	COG0095	Lipoate-protein ligase
KONIH1_RS18665	COG0583	DNA-binding transcription factor activity
KONIH1_RS18670	COG1942	4-Oxalocrotonate Tautomerase
KONIH1_RS18680	COG1082	Xylose isomerase domain protein TIM barrel
KONIH1_RS18685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS18685	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS18690	COG0673	inositol 2-dehydrogenase activity
KONIH1_RS18695	COG2814	Major facilitator Superfamily
KONIH1_RS18705	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KONIH1_RS18725	COG1289	transmembrane transporter activity
KONIH1_RS18745	COG2925	Exonuclease
KONIH1_RS18750	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KONIH1_RS18755	COG0640	Transcriptional regulator
KONIH1_RS18840	COG2205	protein histidine kinase activity
KONIH1_RS18845	COG3604	Transcriptional regulator
KONIH1_RS18860	COG0531	amino acid
KONIH1_RS18865	COG0583	DNA-binding transcription factor activity
KONIH1_RS18870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KONIH1_RS18880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KONIH1_RS18895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KONIH1_RS18905	COG0107	imidazoleglycerol-phosphate synthase activity
KONIH1_RS18915	COG1215	transferase activity, transferring glycosyl groups
KONIH1_RS19010	COG2244	polysaccharide biosynthetic process
KONIH1_RS19015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KONIH1_RS19045	COG1253	flavin adenine dinucleotide binding
KONIH1_RS19050	COG2982	Protein involved in outer membrane biogenesis
KONIH1_RS19065	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KONIH1_RS19070	COG0443	Heat shock 70 kDa protein
KONIH1_RS19075	COG0372	Belongs to the citrate synthase family
KONIH1_RS19080	COG2205	protein histidine kinase activity
KONIH1_RS19095	COG1301	dicarboxylic acid transport
KONIH1_RS19105	COG4608	Belongs to the ABC transporter superfamily
KONIH1_RS19110	COG0444	Belongs to the ABC transporter superfamily
KONIH1_RS19115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KONIH1_RS19120	COG0601	transmembrane transport
KONIH1_RS19135	COG2267	carboxylic ester hydrolase activity
KONIH1_RS19145	COG1522	sequence-specific DNA binding
KONIH1_RS19160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS19190	COG2205	protein histidine kinase activity
KONIH1_RS19195	COG0745	RESPONSE REGULATOR receiver
KONIH1_RS19200	COG0826	peptidase U32
KONIH1_RS19220	COG4608	Belongs to the ABC transporter superfamily
KONIH1_RS19225	COG0444	Belongs to the ABC transporter superfamily
KONIH1_RS19230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KONIH1_RS19235	COG0601	transmembrane transport
KONIH1_RS19240	COG0747	negative chemotaxis
KONIH1_RS19245	COG4948	Mandelate Racemase Muconate Lactonizing
KONIH1_RS19250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KONIH1_RS19260	COG1070	Carbohydrate kinase
KONIH1_RS19290	COG1830	Aldolase
KONIH1_RS19295	COG0351	phosphomethylpyrimidine kinase
KONIH1_RS19305	COG2015	COG2015, Alkyl sulfatase and related hydrolases
KONIH1_RS19315	COG0583	DNA-binding transcription factor activity
KONIH1_RS19325	COG2252	PERMEase
KONIH1_RS19330	COG0583	DNA-binding transcription factor activity
KONIH1_RS19335	COG5455	response to cobalt ion
KONIH1_RS19355	COG4808	Protein conserved in bacteria
KONIH1_RS19360	COG4807	Protein conserved in bacteria
KONIH1_RS19370	COG3275	phosphorelay sensor kinase activity
KONIH1_RS19375	COG0789	Transcriptional regulator
KONIH1_RS19380	COG1174	glycine betaine transport
KONIH1_RS19385	COG1125	glycine betaine transport
KONIH1_RS19390	COG1174	glycine betaine transport
KONIH1_RS19395	COG1732	Glycine betaine
KONIH1_RS19400	COG1472	Belongs to the glycosyl hydrolase 3 family
KONIH1_RS19405	COG0277	FAD linked oxidase domain protein
KONIH1_RS19415	COG1686	Belongs to the peptidase S11 family
KONIH1_RS19430	COG0586	Pfam SNARE associated Golgi protein
KONIH1_RS19435	COG1538	Outer membrane efflux protein
KONIH1_RS19440	COG2226	methyltransferase
KONIH1_RS19445	COG2723	6-phospho-beta-galactosidase activity
KONIH1_RS19460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KONIH1_RS19465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KONIH1_RS19470	COG0625	glutathione transferase activity
KONIH1_RS19485	COG2271	Major facilitator Superfamily
KONIH1_RS19490	COG0583	DNA-binding transcription factor activity
KONIH1_RS19500	COG1346	cytolysis
KONIH1_RS19510	COG2949	membrane
KONIH1_RS19520	COG1129	ABC transporter
KONIH1_RS19535	COG2311	Membrane
KONIH1_RS19550	COG4771	TonB-dependent receptor
KONIH1_RS19555	COG0833	amino acid
KONIH1_RS19560	COG0583	DNA-binding transcription factor activity
KONIH1_RS19565	COG2855	membrane
KONIH1_RS19575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KONIH1_RS19575	COG1522	sequence-specific DNA binding
KONIH1_RS19580	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KONIH1_RS19585	COG2313	pseudouridylate synthase activity
KONIH1_RS19590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KONIH1_RS19595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KONIH1_RS19595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KONIH1_RS19595	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KONIH1_RS19600	COG1105	Belongs to the carbohydrate kinase PfkB family
KONIH1_RS19605	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS19605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS19610	COG2814	Major facilitator Superfamily
KONIH1_RS19620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KONIH1_RS19625	COG0246	Mannitol dehydrogenase
KONIH1_RS19630	COG0523	cobalamin synthesis protein
KONIH1_RS19635	COG0671	phosphoesterase, PA-phosphatase related
KONIH1_RS19640	COG0791	NLP P60 protein
KONIH1_RS19645	COG2200	EAL domain
KONIH1_RS19650	COG4166	transmembrane transport
KONIH1_RS19655	COG4174	ABC transporter (Permease)
KONIH1_RS19660	COG4239	(ABC) transporter, permease
KONIH1_RS19665	COG4172	Belongs to the ABC transporter superfamily
KONIH1_RS19675	COG2814	Major facilitator Superfamily
KONIH1_RS19680	COG1187	pseudouridine synthase activity
KONIH1_RS19685	COG1061	Type III restriction enzyme res subunit
KONIH1_RS19695	COG0494	nUDIX hydrolase
KONIH1_RS19700	COG1349	DNA-binding transcription factor activity
KONIH1_RS19760	COG0628	permease
KONIH1_RS19775	COG0659	secondary active sulfate transmembrane transporter activity
KONIH1_RS19780	COG2239	Acts as a magnesium transporter
KONIH1_RS19785	COG4615	Cyclic peptide transporter
KONIH1_RS19790	COG3145	DNA-N1-methyladenine dioxygenase activity
KONIH1_RS19795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KONIH1_RS19795	COG2169	Transcriptional regulator
KONIH1_RS19810	COG0642	Histidine kinase
KONIH1_RS19810	COG2198	Histidine kinase
KONIH1_RS19820	COG2205	protein histidine kinase activity
KONIH1_RS19820	COG0784	Response regulator, receiver
KONIH1_RS19845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KONIH1_RS19850	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KONIH1_RS19855	COG0583	DNA-binding transcription factor activity
KONIH1_RS19860	COG0584	glycerophosphoryl diester phosphodiesterase
KONIH1_RS19865	COG2271	Major facilitator Superfamily
KONIH1_RS19870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KONIH1_RS19880	COG0247	lactate metabolic process
KONIH1_RS19890	COG2271	Major facilitator Superfamily
KONIH1_RS19900	COG1414	Transcriptional regulator
KONIH1_RS19955	COG3647	Membrane
KONIH1_RS19985	COG1169	isochorismate synthase
KONIH1_RS19990	COG2153	protein acetylation
KONIH1_RS20000	COG0582	viral genome integration into host DNA
KONIH1_RS20020	COG3121	Chaperone
KONIH1_RS20030	COG0582	viral genome integration into host DNA
KONIH1_RS20040	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KONIH1_RS20045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KONIH1_RS20050	COG0713	ATP synthesis coupled electron transport
KONIH1_RS20055	COG0839	Belongs to the complex I subunit 6 family
KONIH1_RS20100	COG0583	DNA-binding transcription factor activity
KONIH1_RS20105	COG0436	Aminotransferase
KONIH1_RS20115	COG0471	metal ion transport
KONIH1_RS20115	COG0490	domain, Protein
KONIH1_RS20120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KONIH1_RS20145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KONIH1_RS20150	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KONIH1_RS20155	COG3037	sugar-specific permease SgaT UlaA
KONIH1_RS20165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS20170	COG1609	Transcriptional regulator
KONIH1_RS20180	COG0622	Phosphoesterase
KONIH1_RS20185	COG0625	glutathione transferase activity
KONIH1_RS20190	COG0625	glutathione transferase activity
KONIH1_RS20195	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KONIH1_RS20200	COG1090	epimerase
KONIH1_RS20220	COG4598	ABC transporter
KONIH1_RS20225	COG4160	amino acid transport
KONIH1_RS20245	COG0163	prenyltransferase activity
KONIH1_RS20250	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KONIH1_RS20255	COG1286	toxin biosynthetic process
KONIH1_RS20260	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KONIH1_RS20265	COG0285	dihydrofolate synthase activity
KONIH1_RS20275	COG0586	Pfam SNARE associated Golgi protein
KONIH1_RS20285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KONIH1_RS20305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KONIH1_RS20320	COG3101	peptidyl-lysine hydroxylation
KONIH1_RS20325	COG0730	response to heat
KONIH1_RS20350	COG2062	phosphohistidine phosphatase, SixA
KONIH1_RS20365	COG3691	Protein conserved in bacteria
KONIH1_RS20380	COG2116	formate transmembrane transporter activity
KONIH1_RS20405	COG0583	DNA-binding transcription factor activity
KONIH1_RS20410	COG2807	transmembrane transport
KONIH1_RS20415	COG0436	Aminotransferase
KONIH1_RS20420	COG3275	phosphorelay sensor kinase activity
KONIH1_RS20425	COG3279	Response regulator of the LytR AlgR family
KONIH1_RS20440	COG3961	Belongs to the TPP enzyme family
KONIH1_RS20445	COG0667	Aldo Keto reductase
KONIH1_RS20460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KONIH1_RS20465	COG2200	EAL domain
KONIH1_RS20465	COG2199	diguanylate cyclase activity
KONIH1_RS20480	COG3415	Transposase
KONIH1_RS20485	COG3415	Transposase
KONIH1_RS20515	COG0583	DNA-binding transcription factor activity
KONIH1_RS20520	COG2211	Major facilitator Superfamily
KONIH1_RS20525	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KONIH1_RS20530	COG0583	DNA-binding transcription factor activity
KONIH1_RS20535	COG0385	Bile acid
KONIH1_RS20540	COG3530	Putative quorum-sensing-regulated virulence factor
KONIH1_RS20560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KONIH1_RS20605	COG4319	ketosteroid isomerase
KONIH1_RS20615	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KONIH1_RS20620	COG4208	sulfate ABC transporter
KONIH1_RS20625	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KONIH1_RS20630	COG4150	thiosulfate binding
KONIH1_RS20635	COG2837	iron assimilation
KONIH1_RS20655	COG0860	N-Acetylmuramoyl-L-alanine amidase
KONIH1_RS20665	COG2207	Transcriptional regulator
KONIH1_RS20735	COG4766	ethanolamine catabolic process
KONIH1_RS20745	COG4810	utilization protein
KONIH1_RS20755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KONIH1_RS20760	COG5342	invasion associated locus B
KONIH1_RS20770	COG0493	'glutamate synthase
KONIH1_RS20770	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KONIH1_RS20775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KONIH1_RS20780	COG1393	Belongs to the ArsC family
KONIH1_RS20795	COG0400	carboxylic ester hydrolase activity
KONIH1_RS20805	COG2321	neutral zinc metallopeptidase
KONIH1_RS20815	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KONIH1_RS20825	COG2716	regulation of RNA biosynthetic process
KONIH1_RS20830	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KONIH1_RS20835	COG0628	permease
KONIH1_RS20840	COG4783	chaperone-mediated protein folding
KONIH1_RS20845	COG1393	Belongs to the ArsC family
KONIH1_RS20855	COG2233	PERMEase
KONIH1_RS20860	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KONIH1_RS20865	COG2723	6-phospho-beta-galactosidase activity
KONIH1_RS20880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KONIH1_RS20890	COG2211	Major facilitator Superfamily
KONIH1_RS20910	COG0248	Ppx GppA phosphatase
KONIH1_RS20915	COG2200	EAL domain
KONIH1_RS20925	COG0583	DNA-binding transcription factor activity
KONIH1_RS20935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KONIH1_RS20935	COG0519	Catalyzes the synthesis of GMP from XMP
KONIH1_RS20940	COG0516	GMP reductase activity
KONIH1_RS20940	COG0517	IMP dehydrogenase activity
KONIH1_RS20945	COG1570	exodeoxyribonuclease VII activity
KONIH1_RS20960	COG1645	bacterial-type flagellum-dependent swarming motility
KONIH1_RS20985	COG2976	Protein conserved in bacteria
KONIH1_RS21015	COG4953	penicillin-binding protein 1C
KONIH1_RS21020	COG2373	Large extracellular alpha-helical protein
KONIH1_RS21030	COG1473	amidohydrolase
KONIH1_RS21035	COG2897	thiosulfate sulfurtransferase activity
KONIH1_RS21050	COG2975	iron-sulfur cluster assembly
KONIH1_RS21055	COG0633	Ferredoxin
KONIH1_RS21075	COG0822	iron-sulfur transferase activity
KONIH1_RS21100	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
KONIH1_RS21105	COG3683	transport system, periplasmic component
KONIH1_RS21110	COG3711	transcriptional antiterminator
KONIH1_RS21115	COG2814	Major facilitator Superfamily
KONIH1_RS21120	COG2017	converts alpha-aldose to the beta-anomer
KONIH1_RS21125	COG0477	Major facilitator Superfamily
KONIH1_RS21125	COG2814	Major facilitator Superfamily
KONIH1_RS21130	COG0457	Tetratricopeptide repeat
KONIH1_RS21135	COG1940	carbohydrate kinase activity
KONIH1_RS21140	COG2259	Doxx family
KONIH1_RS21150	COG1017	nitric oxide dioxygenase activity
KONIH1_RS21150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KONIH1_RS21155	COG0347	Belongs to the P(II) protein family
KONIH1_RS21160	COG2204	response regulator
KONIH1_RS21165	COG3170	Tfp pilus assembly protein FimV
KONIH1_RS21170	COG2205	protein histidine kinase activity
KONIH1_RS21175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KONIH1_RS21175	COG0047	phosphoribosylformylglycinamidine synthase activity
KONIH1_RS21190	COG0560	Phosphoserine phosphatase
KONIH1_RS21195	COG1737	Transcriptional regulator
KONIH1_RS21200	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KONIH1_RS21210	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KONIH1_RS21230	COG0681	Belongs to the peptidase S26 family
KONIH1_RS21240	COG3086	response to oxidative stress
KONIH1_RS21250	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
KONIH1_RS21260	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KONIH1_RS21270	COG0513	Belongs to the DEAD box helicase family
KONIH1_RS21285	COG3385	transposase activity
KONIH1_RS21290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KONIH1_RS21295	COG3118	belongs to the thioredoxin family
KONIH1_RS21300	COG3148	PFAM DTW domain containing protein
KONIH1_RS21310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KONIH1_RS21315	COG5544	Lipoprotein
KONIH1_RS21320	COG0477	Major facilitator Superfamily
KONIH1_RS21350	COG0542	response to heat
KONIH1_RS21365	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KONIH1_RS21370	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KONIH1_RS21375	COG1605	Chorismate mutase
KONIH1_RS21375	COG0077	Prephenate dehydratase
KONIH1_RS21385	COG0287	Prephenate dehydrogenase
KONIH1_RS21385	COG1605	Chorismate mutase
KONIH1_RS21390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KONIH1_RS21400	COG2199	diguanylate cyclase activity
KONIH1_RS21405	COG2885	chlorophyll binding
KONIH1_RS21460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KONIH1_RS21490	COG4695	Portal protein
KONIH1_RS21640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KONIH1_RS21645	COG4137	Cytochrome C assembly protein
KONIH1_RS21650	COG4536	flavin adenine dinucleotide binding
KONIH1_RS21665	COG0497	DNA recombination
KONIH1_RS21680	COG2867	negative regulation of translational initiation
KONIH1_RS21690	COG0582	viral genome integration into host DNA
KONIH1_RS21695	COG2801	Transposase and inactivated derivatives
KONIH1_RS21700	COG2963	transposase activity
KONIH1_RS21735	COG2801	Transposase and inactivated derivatives
KONIH1_RS21765	COG0582	viral genome integration into host DNA
KONIH1_RS21775	COG4585	Histidine kinase
KONIH1_RS21780	COG3039	Transposase
KONIH1_RS21790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KONIH1_RS21840	COG3451	type IV secretory pathway VirB4
KONIH1_RS21890	COG3039	Transposase
KONIH1_RS21960	COG3121	Chaperone
KONIH1_RS21975	COG2205	protein histidine kinase activity
KONIH1_RS21975	COG2198	Histidine kinase
KONIH1_RS21975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS21975	COG0784	Response regulator, receiver
KONIH1_RS21980	COG2197	response regulator
KONIH1_RS22015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KONIH1_RS22025	COG0235	Class ii aldolase
KONIH1_RS22035	COG4235	cytochrome complex assembly
KONIH1_RS22035	COG3088	subunit of a heme lyase
KONIH1_RS22040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KONIH1_RS22045	COG1138	Cytochrome C-type biogenesis protein
KONIH1_RS22055	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KONIH1_RS22060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KONIH1_RS22075	COG1858	cytochrome C peroxidase
KONIH1_RS22080	COG2814	Major facilitator Superfamily
KONIH1_RS22085	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS22105	COG3188	usher protein
KONIH1_RS22130	COG3284	Transcriptional regulator
KONIH1_RS22135	COG0640	Transcriptional regulator
KONIH1_RS22140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KONIH1_RS22170	COG4575	ribosome binding
KONIH1_RS22180	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KONIH1_RS22185	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KONIH1_RS22195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KONIH1_RS22200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KONIH1_RS22210	COG4176	ABC-type proline glycine betaine transport system permease component
KONIH1_RS22220	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KONIH1_RS22230	COG1846	Transcriptional regulator
KONIH1_RS22235	COG1566	PFAM secretion protein HlyD family protein
KONIH1_RS22240	COG2814	Major facilitator Superfamily
KONIH1_RS22245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KONIH1_RS22265	COG1238	metal cluster binding
KONIH1_RS22270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KONIH1_RS22275	COG2823	Periplasmic or secreted lipoprotein
KONIH1_RS22310	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KONIH1_RS22330	COG1546	Belongs to the CinA family
KONIH1_RS22340	COG0803	Belongs to the bacterial solute-binding protein 9 family
KONIH1_RS22345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KONIH1_RS22355	COG2951	lytic endotransglycosylase activity
KONIH1_RS22360	COG3730	PTS system glucitol sorbitol-specific
KONIH1_RS22365	COG3732	PTS system glucitol sorbitol-specific
KONIH1_RS22375	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS22380	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS22385	COG1349	DNA-binding transcription factor activity
KONIH1_RS22410	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
KONIH1_RS22415	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KONIH1_RS22420	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KONIH1_RS22425	COG1609	Transcriptional regulator
KONIH1_RS22430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS22430	COG1263	PTS System
KONIH1_RS22435	COG2723	6-phospho-beta-galactosidase activity
KONIH1_RS22440	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KONIH1_RS22450	COG3260	NADH ubiquinone oxidoreductase 20
KONIH1_RS22455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KONIH1_RS22460	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
KONIH1_RS22460	COG3261	NADH dehydrogenase
KONIH1_RS22465	COG0650	Formate hydrogenlyase subunit 4
KONIH1_RS22470	COG0651	ATP synthesis coupled electron transport
KONIH1_RS22475	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KONIH1_RS22490	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KONIH1_RS22495	COG0298	carbon dioxide binding
KONIH1_RS22500	COG0409	Hydrogenase expression formation protein
KONIH1_RS22505	COG0309	Hydrogenase expression formation protein (HypE)
KONIH1_RS22515	COG0657	acetylesterase activity
KONIH1_RS22515	COG2755	lipolytic protein G-D-S-L family
KONIH1_RS22520	COG2723	6-phospho-beta-galactosidase activity
KONIH1_RS22535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KONIH1_RS22540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KONIH1_RS22545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KONIH1_RS22550	COG1447	Phosphotransferase system cellobiose-specific component IIA
KONIH1_RS22555	COG1940	carbohydrate kinase activity
KONIH1_RS22560	COG1609	Transcriptional regulator
KONIH1_RS22570	COG1121	(ABC) transporter
KONIH1_RS22575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KONIH1_RS22580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KONIH1_RS22600	COG3720	iron ion transport
KONIH1_RS22605	COG4558	Periplasmic binding protein
KONIH1_RS22610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KONIH1_RS22615	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KONIH1_RS22625	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS22630	COG2271	Major facilitator Superfamily
KONIH1_RS22635	COG1063	alcohol dehydrogenase
KONIH1_RS22645	COG1454	alcohol dehydrogenase
KONIH1_RS22685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KONIH1_RS22690	COG1538	Outer membrane efflux protein
KONIH1_RS22700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KONIH1_RS22705	COG1132	(ABC) transporter
KONIH1_RS22735	COG3539	Fimbrial protein
KONIH1_RS22745	COG3121	Chaperone
KONIH1_RS22750	COG3188	usher protein
KONIH1_RS22760	COG3539	Fimbrial protein
KONIH1_RS22840	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KONIH1_RS22860	COG0477	Major facilitator Superfamily
KONIH1_RS22870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KONIH1_RS22875	COG4942	peptidase
KONIH1_RS22875	COG1388	LysM domain
KONIH1_RS22935	COG2234	aminopeptidase activity
KONIH1_RS22950	COG0697	spore germination
KONIH1_RS22955	COG1104	cysteine desulfurase activity
KONIH1_RS22985	COG0720	synthase
KONIH1_RS22990	COG0602	queuosine metabolic process
KONIH1_RS23010	COG3956	TIGRFAM MazG family protein
KONIH1_RS23015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KONIH1_RS23025	COG2205	protein histidine kinase activity
KONIH1_RS23025	COG3437	response regulator, receiver
KONIH1_RS23025	COG4999	Histidine kinase
KONIH1_RS23025	COG3850	Histidine kinase
KONIH1_RS23030	COG1929	Belongs to the glycerate kinase type-1 family
KONIH1_RS23035	COG4948	Mandelate Racemase Muconate Lactonizing
KONIH1_RS23040	COG4948	Mandelate Racemase Muconate Lactonizing
KONIH1_RS23045	COG2271	Major facilitator Superfamily
KONIH1_RS23050	COG0716	FMN binding
KONIH1_RS23055	COG0564	pseudouridine synthase activity
KONIH1_RS23060	COG3098	single-species biofilm formation
KONIH1_RS23080	COG1611	Belongs to the LOG family
KONIH1_RS23085	COG0814	amino acid
KONIH1_RS23090	COG1760	l-serine dehydratase
KONIH1_RS23095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KONIH1_RS23110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KONIH1_RS23125	COG0235	Class ii aldolase
KONIH1_RS23130	COG0738	Major facilitator superfamily
KONIH1_RS23150	COG1349	DNA-binding transcription factor activity
KONIH1_RS23160	COG2363	Small membrane protein
KONIH1_RS23165	COG0583	DNA-binding transcription factor activity
KONIH1_RS23175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KONIH1_RS23180	COG2166	iron-sulfur cluster assembly
KONIH1_RS23185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KONIH1_RS23195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KONIH1_RS23200	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KONIH1_RS23365	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KONIH1_RS23380	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
KONIH1_RS23395	COG1454	alcohol dehydrogenase
KONIH1_RS23395	COG1012	belongs to the aldehyde dehydrogenase family
KONIH1_RS23400	COG4656	Part of a membrane complex involved in electron transport
KONIH1_RS23430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KONIH1_RS23435	COG0860	N-Acetylmuramoyl-L-alanine amidase
KONIH1_RS23440	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KONIH1_RS23440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KONIH1_RS23445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KONIH1_RS23450	COG1074	ATP-dependent DNA helicase activity
KONIH1_RS23455	COG1025	Belongs to the peptidase M16 family
KONIH1_RS23460	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KONIH1_RS23465	COG4967	type IV pilus modification protein PilV
KONIH1_RS23475	COG4795	General secretion pathway protein
KONIH1_RS23480	COG2165	general secretion pathway protein
KONIH1_RS23515	COG0861	Integral membrane protein TerC family
KONIH1_RS23525	COG0667	Aldo Keto reductase
KONIH1_RS23540	COG1609	Transcriptional regulator
KONIH1_RS23550	COG2186	Transcriptional regulator
KONIH1_RS23555	COG2723	6-phospho-beta-galactosidase activity
KONIH1_RS23560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KONIH1_RS23565	COG1609	Transcriptional regulator
KONIH1_RS23575	COG0583	DNA-binding transcription factor activity
KONIH1_RS23580	COG3539	Fimbrial protein
KONIH1_RS23590	COG3121	Chaperone
KONIH1_RS23595	COG3188	usher protein
KONIH1_RS23605	COG1794	racemase activity, acting on amino acids and derivatives
KONIH1_RS23615	COG1175	transmembrane transport
KONIH1_RS23620	COG0395	ABC-type sugar transport system, permease component
KONIH1_RS23625	COG3842	ATPase activity
KONIH1_RS23635	COG0823	Involved in the tonB-independent uptake of proteins
KONIH1_RS23660	COG2814	Major facilitator Superfamily
KONIH1_RS23665	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS23670	COG0823	Involved in the tonB-independent uptake of proteins
KONIH1_RS23680	COG0183	Belongs to the thiolase family
KONIH1_RS23695	COG0814	amino acid
KONIH1_RS23700	COG0667	Aldo Keto reductase
KONIH1_RS23745	COG0640	Transcriptional regulator
KONIH1_RS23760	COG0697	spore germination
KONIH1_RS23765	COG1846	Transcriptional regulator
KONIH1_RS23770	COG1522	sequence-specific DNA binding
KONIH1_RS23780	COG2388	GCN5-related N-acetyl-transferase
KONIH1_RS23785	COG3592	Divergent 4Fe-4S mono-cluster
KONIH1_RS23800	COG1289	transmembrane transporter activity
KONIH1_RS23805	COG1538	Outer membrane efflux protein
KONIH1_RS23810	COG2909	trisaccharide binding
KONIH1_RS23835	COG1349	DNA-binding transcription factor activity
KONIH1_RS23850	COG1349	DNA-binding transcription factor activity
KONIH1_RS23855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KONIH1_RS23860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KONIH1_RS23865	COG0738	Major facilitator superfamily
KONIH1_RS23910	COG1929	Belongs to the glycerate kinase type-1 family
KONIH1_RS23915	COG3835	regulator
KONIH1_RS23920	COG2223	nitrite transmembrane transporter activity
KONIH1_RS23935	COG1393	Belongs to the ArsC family
KONIH1_RS23940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KONIH1_RS23950	COG2814	Major facilitator Superfamily
KONIH1_RS23955	COG0778	Nitroreductase
KONIH1_RS23965	COG0667	Aldo Keto reductase
KONIH1_RS23975	COG5002	protein histidine kinase activity
KONIH1_RS24005	COG3039	Transposase
KONIH1_RS24010	COG0656	L-ascorbic acid biosynthetic process
KONIH1_RS24015	COG0667	Aldo Keto reductase
KONIH1_RS24025	COG0702	epimerase
KONIH1_RS24055	COG4221	oxidoreductase activity
KONIH1_RS24070	COG1064	alcohol dehydrogenase
KONIH1_RS24080	COG1309	transcriptional regulator
KONIH1_RS24090	COG0582	viral genome integration into host DNA
KONIH1_RS24100	COG4942	peptidase
KONIH1_RS24105	COG0583	DNA-binding transcription factor activity
KONIH1_RS24110	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KONIH1_RS24120	COG1811	Na channel or pump
KONIH1_RS24140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KONIH1_RS24155	COG0716	FMN binding
KONIH1_RS24165	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KONIH1_RS24185	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS24185	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS24190	COG3715	PTS system
KONIH1_RS24195	COG3716	PTS system mannose fructose sorbose family IID component
KONIH1_RS24210	COG1272	protein, Hemolysin III
KONIH1_RS24220	COG1737	Transcriptional regulator
KONIH1_RS24225	COG2723	6-phospho-beta-galactosidase activity
KONIH1_RS24230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KONIH1_RS24235	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS24255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KONIH1_RS24260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KONIH1_RS24265	COG0006	proline dipeptidase activity
KONIH1_RS24280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KONIH1_RS24285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KONIH1_RS24300	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KONIH1_RS24300	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KONIH1_RS24305	COG1703	isobutyryl-CoA mutase activity
KONIH1_RS24310	COG1024	Enoyl-CoA hydratase
KONIH1_RS24315	COG0427	acetyl-CoA hydrolase
KONIH1_RS24320	COG0583	DNA-binding transcription factor activity
KONIH1_RS24325	COG2968	Membrane
KONIH1_RS24335	COG0668	transmembrane transport
KONIH1_RS24340	COG0191	fructose-bisphosphate aldolase activity
KONIH1_RS24375	COG1122	ATPase activity
KONIH1_RS24380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KONIH1_RS24385	COG0501	Belongs to the peptidase M48B family
KONIH1_RS24405	COG2814	Major facilitator Superfamily
KONIH1_RS24415	COG2356	endonuclease I
KONIH1_RS24420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KONIH1_RS24425	COG0189	ligase activity
KONIH1_RS24440	COG2197	response regulator
KONIH1_RS24445	COG2805	Type II/IV secretion system protein
KONIH1_RS24450	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KONIH1_RS24455	COG0762	integral membrane protein
KONIH1_RS24470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KONIH1_RS24475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KONIH1_RS24480	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KONIH1_RS24495	COG3171	Protein conserved in bacteria
KONIH1_RS24505	COG1194	a g-specific adenine glycosylase
KONIH1_RS24520	COG2211	Major facilitator Superfamily
KONIH1_RS24525	COG1982	Orn Lys Arg decarboxylase major
KONIH1_RS24530	COG1811	Na channel or pump
KONIH1_RS24540	COG0471	metal ion transport
KONIH1_RS24550	COG0626	cystathionine gamma-synthase activity
KONIH1_RS24570	COG2365	Tyrosine phosphatase family
KONIH1_RS24580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KONIH1_RS24585	COG0754	glutathionylspermidine amidase activity
KONIH1_RS24595	COG0625	glutathione transferase activity
KONIH1_RS24615	COG0848	biopolymer transport protein
KONIH1_RS24630	COG0586	Pfam SNARE associated Golgi protein
KONIH1_RS24635	COG2207	Transcriptional regulator
KONIH1_RS24640	COG1979	alcohol dehydrogenase
KONIH1_RS24655	COG1032	radical SAM domain protein
KONIH1_RS24690	COG2801	Transposase and inactivated derivatives
KONIH1_RS24715	COG0604	alcohol dehydrogenase
KONIH1_RS24750	COG3344	reverse transcriptase
KONIH1_RS24755	COG2801	Transposase and inactivated derivatives
KONIH1_RS24795	COG0697	spore germination
KONIH1_RS24800	COG1234	tRNA 3'-trailer cleavage
KONIH1_RS24810	COG1902	pentaerythritol trinitrate reductase activity
KONIH1_RS24815	COG0640	Transcriptional regulator
KONIH1_RS24820	COG2963	transposase activity
KONIH1_RS24850	COG1032	radical SAM domain protein
KONIH1_RS24855	COG2132	Multicopper oxidase
KONIH1_RS24860	COG0204	Acyl-transferase
KONIH1_RS24870	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KONIH1_RS24875	COG3111	PFAM Bacterial OB fold (BOF) protein
KONIH1_RS24880	COG0745	RESPONSE REGULATOR receiver
KONIH1_RS24885	COG0642	Histidine kinase
KONIH1_RS24890	COG2249	NAD(P)H dehydrogenase (quinone) activity
KONIH1_RS24895	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KONIH1_RS24905	COG3150	esterase
KONIH1_RS24910	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KONIH1_RS24915	COG3151	Protein conserved in bacteria
KONIH1_RS24920	COG0494	nUDIX hydrolase
KONIH1_RS24935	COG0754	glutathionylspermidine amidase activity
KONIH1_RS24940	COG3384	dioxygenase
KONIH1_RS24950	COG3539	Fimbrial protein
KONIH1_RS24955	COG3188	usher protein
KONIH1_RS24960	COG3121	Chaperone
KONIH1_RS24965	COG3539	Fimbrial protein
KONIH1_RS24975	COG2960	long-chain fatty acid transporting porin activity
KONIH1_RS24995	COG3025	triphosphatase activity
KONIH1_RS25000	COG4991	sh3 domain protein
KONIH1_RS25015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KONIH1_RS25070	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KONIH1_RS25075	COG0358	DNA primase activity
KONIH1_RS25120	COG2376	Dihydroxyacetone kinase
KONIH1_RS25125	COG1461	Dihydroxyacetone kinase
KONIH1_RS25145	COG2375	cellular response to nickel ion
KONIH1_RS25150	COG1695	Transcriptional regulator
KONIH1_RS25160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KONIH1_RS25165	COG1609	Transcriptional regulator
KONIH1_RS25170	COG3250	beta-galactosidase activity
KONIH1_RS25175	COG2731	YhcH YjgK YiaL family protein
KONIH1_RS25180	COG0531	amino acid
KONIH1_RS25185	COG0531	amino acid
KONIH1_RS25195	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
KONIH1_RS25195	COG3408	Glycogen debranching enzyme
KONIH1_RS25240	COG0446	pyridine nucleotide-disulphide oxidoreductase
KONIH1_RS25240	COG1902	pentaerythritol trinitrate reductase activity
KONIH1_RS25250	COG2211	Major facilitator Superfamily
KONIH1_RS25260	COG3507	Belongs to the glycosyl hydrolase 43 family
KONIH1_RS25265	COG1451	nucleotide metabolic process
KONIH1_RS25270	COG0673	inositol 2-dehydrogenase activity
KONIH1_RS25290	COG2721	sulfolactate sulfo-lyase activity
KONIH1_RS25300	COG2271	Major facilitator Superfamily
KONIH1_RS25305	COG2186	Transcriptional regulator
KONIH1_RS25310	COG0586	Pfam SNARE associated Golgi protein
KONIH1_RS25320	COG1422	Protein of unknown function (DUF1090)
KONIH1_RS25325	COG4575	ribosome binding
KONIH1_RS25330	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
KONIH1_RS25340	COG2259	Doxx family
KONIH1_RS25345	COG0435	Glutathione S-transferase
KONIH1_RS25350	COG3152	Membrane
KONIH1_RS25355	COG0583	DNA-binding transcription factor activity
KONIH1_RS25360	COG1741	Belongs to the pirin family
KONIH1_RS25370	COG1929	Belongs to the glycerate kinase type-1 family
KONIH1_RS25375	COG2084	Dehydrogenase
KONIH1_RS25385	COG2271	Major facilitator Superfamily
KONIH1_RS25390	COG2721	sulfolactate sulfo-lyase activity
KONIH1_RS25395	COG1349	DNA-binding transcription factor activity
KONIH1_RS25405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS25415	COG3716	PTS system mannose fructose sorbose family IID component
KONIH1_RS25420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS25425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KONIH1_RS25430	COG2222	sugar isomerase
KONIH1_RS25445	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KONIH1_RS25465	COG2823	Periplasmic or secreted lipoprotein
KONIH1_RS25470	COG0701	Predicted permease
KONIH1_RS25475	COG0702	epimerase
KONIH1_RS25480	COG0693	protein deglycase activity
KONIH1_RS25490	COG2827	Endonuclease containing a URI domain
KONIH1_RS25495	COG3153	acetyltransferase
KONIH1_RS25500	COG3154	lipid carrier protein
KONIH1_RS25505	COG0826	peptidase U32
KONIH1_RS25510	COG0826	peptidase U32
KONIH1_RS25515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KONIH1_RS25520	COG0814	amino acid
KONIH1_RS25525	COG0513	Belongs to the DEAD box helicase family
KONIH1_RS25555	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KONIH1_RS25560	COG0195	Participates in both transcription termination and antitermination
KONIH1_RS25585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KONIH1_RS25595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KONIH1_RS25600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KONIH1_RS25610	COG1534	Rna-binding protein
KONIH1_RS25620	COG2027	D-alanyl-D-alanine carboxypeptidase
KONIH1_RS25630	COG0697	spore germination
KONIH1_RS25645	COG0142	geranyltranstransferase activity
KONIH1_RS25650	COG3423	Transcriptional regulator
KONIH1_RS25660	COG5007	Belongs to the BolA IbaG family
KONIH1_RS25665	COG3113	response to antibiotic
KONIH1_RS25670	COG2854	intermembrane phospholipid transfer
KONIH1_RS25675	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KONIH1_RS25680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KONIH1_RS25685	COG1127	ABC transporter
KONIH1_RS25690	COG0530	calcium, potassium:sodium antiporter activity
KONIH1_RS25700	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KONIH1_RS25705	COG3117	lipopolysaccharide transmembrane transporter activity
KONIH1_RS25710	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KONIH1_RS25715	COG1137	ATPase activity
KONIH1_RS25720	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KONIH1_RS25725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KONIH1_RS25730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS25735	COG1660	Displays ATPase and GTPase activities
KONIH1_RS25740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS25745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KONIH1_RS25750	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KONIH1_RS25755	COG5002	protein histidine kinase activity
KONIH1_RS25755	COG2198	Histidine kinase
KONIH1_RS25755	COG0784	Response regulator, receiver
KONIH1_RS25760	COG1242	4 iron, 4 sulfur cluster binding
KONIH1_RS25765	COG0069	glutamate synthase activity
KONIH1_RS25765	COG0067	glutamate synthase
KONIH1_RS25765	COG0070	glutamate synthase
KONIH1_RS25770	COG0493	'glutamate synthase
KONIH1_RS25775	COG2731	YhcH YjgK YiaL family protein
KONIH1_RS25805	COG2969	positive regulation of protein catabolic process
KONIH1_RS25810	COG0625	glutathione transferase activity
KONIH1_RS25825	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KONIH1_RS25830	COG3105	Protein conserved in bacteria
KONIH1_RS25835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KONIH1_RS25840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KONIH1_RS25855	COG5016	pyruvate
KONIH1_RS25855	COG0511	ligase activity, forming carbon-carbon bonds
KONIH1_RS25865	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KONIH1_RS25870	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KONIH1_RS25875	COG0471	metal ion transport
KONIH1_RS25885	COG1802	Transcriptional regulator
KONIH1_RS25910	COG2732	(Barnase) inhibitor
KONIH1_RS25915	COG1289	transmembrane transporter activity
KONIH1_RS25930	COG0583	DNA-binding transcription factor activity
KONIH1_RS25935	COG1349	DNA-binding transcription factor activity
KONIH1_RS25940	COG0312	modulator of DNA gyrase
KONIH1_RS25945	COG3164	Protein of unknown function
KONIH1_RS25960	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KONIH1_RS25965	COG1792	Involved in formation and maintenance of cell shape
KONIH1_RS25970	COG1077	Cell shape determining protein MreB Mrl
KONIH1_RS25975	COG2200	EAL domain
KONIH1_RS25975	COG2199	diguanylate cyclase activity
KONIH1_RS25980	COG0604	alcohol dehydrogenase
KONIH1_RS26000	COG0511	ligase activity, forming carbon-carbon bonds
KONIH1_RS26005	COG0439	Biotin carboxylase
KONIH1_RS26010	COG3924	membrane
KONIH1_RS26015	COG4145	pantothenate transmembrane transporter activity
KONIH1_RS26040	COG1309	transcriptional regulator
KONIH1_RS26045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KONIH1_RS26050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KONIH1_RS26090	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KONIH1_RS26115	COG0758	DNA mediated transformation
KONIH1_RS26145	COG0789	Transcriptional regulator
KONIH1_RS26155	COG0203	ribosomal protein L17
KONIH1_RS26160	COG0202	RNA polymerase activity
KONIH1_RS26170	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KONIH1_RS26185	COG0201	protein transport
KONIH1_RS26200	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KONIH1_RS26250	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KONIH1_RS26265	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KONIH1_RS26280	COG0088	Forms part of the polypeptide exit tunnel
KONIH1_RS26290	COG0051	transcription antitermination factor activity, RNA binding
KONIH1_RS26345	COG2964	Protein conserved in bacteria
KONIH1_RS26350	COG0545	Peptidyl-prolyl cis-trans isomerase
KONIH1_RS26360	COG1047	Peptidyl-prolyl cis-trans
KONIH1_RS26365	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KONIH1_RS26380	COG0488	(ABC) transporter
KONIH1_RS26390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KONIH1_RS26400	COG0429	hydrolase of the alpha beta-hydrolase fold
KONIH1_RS26410	COG3954	Phosphoribulokinase
KONIH1_RS26415	COG1765	OsmC-like protein
KONIH1_RS26425	COG1289	transmembrane transporter activity
KONIH1_RS26430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KONIH1_RS26450	COG0738	Major facilitator superfamily
KONIH1_RS26455	COG0402	S-adenosylhomocysteine deaminase activity
KONIH1_RS26460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KONIH1_RS26465	COG2146	nitrite reductase [NAD(P)H] activity
KONIH1_RS26490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KONIH1_RS26495	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KONIH1_RS26500	COG3266	domain, Protein
KONIH1_RS26515	COG4796	Type ii and iii secretion system protein
KONIH1_RS26540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KONIH1_RS26545	COG0494	nUDIX hydrolase
KONIH1_RS26555	COG1011	Hydrolase
KONIH1_RS26560	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KONIH1_RS26575	COG1640	4-alpha-glucanotransferase
KONIH1_RS26580	COG0058	SHG alpha-glucan phosphorylase activity
KONIH1_RS26595	COG1349	DNA-binding transcription factor activity
KONIH1_RS26610	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KONIH1_RS26615	COG0058	SHG alpha-glucan phosphorylase activity
KONIH1_RS26640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KONIH1_RS26645	COG2610	gluconate transmembrane transporter activity
KONIH1_RS26650	COG3265	gluconokinase activity
KONIH1_RS26655	COG1609	Transcriptional regulator
KONIH1_RS26660	COG1741	Belongs to the pirin family
KONIH1_RS26665	COG0673	inositol 2-dehydrogenase activity
KONIH1_RS26675	COG1247	-acetyltransferase
KONIH1_RS26680	COG0405	Gamma-glutamyltransferase
KONIH1_RS26690	COG0584	glycerophosphoryl diester phosphodiesterase
KONIH1_RS26715	COG1414	Transcriptional regulator
KONIH1_RS26720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KONIH1_RS26725	COG2271	Major facilitator Superfamily
KONIH1_RS26730	COG2721	sulfolactate sulfo-lyase activity
KONIH1_RS26755	COG0683	leucine binding
KONIH1_RS26765	COG0683	leucine binding
KONIH1_RS26780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KONIH1_RS26795	COG2177	Part of the ABC transporter FtsEX involved in
KONIH1_RS26800	COG2884	Cell division ATP-binding protein ftsE
KONIH1_RS26805	COG0552	protein localization to endoplasmic reticulum
KONIH1_RS26810	COG0742	ribosomal rna small subunit methyltransferase
KONIH1_RS26815	COG3776	membrane
KONIH1_RS26825	COG3714	YhhN family
KONIH1_RS26840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KONIH1_RS26850	COG0477	Major facilitator Superfamily
KONIH1_RS26855	COG0628	permease
KONIH1_RS26885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KONIH1_RS26905	COG1216	Glycosyl transferase, family 2
KONIH1_RS26930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KONIH1_RS26940	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS26945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KONIH1_RS26950	COG2091	lysine biosynthetic process via aminoadipic acid
KONIH1_RS26990	COG3479	Phenolic acid decarboxylase
KONIH1_RS27005	COG0747	negative chemotaxis
KONIH1_RS27010	COG0601	transmembrane transport
KONIH1_RS27015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KONIH1_RS27020	COG0444	Belongs to the ABC transporter superfamily
KONIH1_RS27040	COG2239	Acts as a magnesium transporter
KONIH1_RS27045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KONIH1_RS27050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KONIH1_RS27055	COG0471	metal ion transport
KONIH1_RS27060	COG3964	amidohydrolase
KONIH1_RS27070	COG2081	HI0933 family
KONIH1_RS27075	COG0306	phosphate transporter
KONIH1_RS27085	COG0589	response to stress
KONIH1_RS27105	COG2610	gluconate transmembrane transporter activity
KONIH1_RS27140	COG1918	ferrous iron import across plasma membrane
KONIH1_RS27145	COG2183	response to ionizing radiation
KONIH1_RS27150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KONIH1_RS27165	COG0671	phosphoesterase, PA-phosphatase related
KONIH1_RS27170	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KONIH1_RS27175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KONIH1_RS27180	COG0625	glutathione transferase activity
KONIH1_RS27185	COG1454	alcohol dehydrogenase
KONIH1_RS27205	COG2197	response regulator
KONIH1_RS27210	COG1028	Short-chain dehydrogenase reductase Sdr
KONIH1_RS27215	COG0583	DNA-binding transcription factor activity
KONIH1_RS27220	COG1295	ribonuclease BN
KONIH1_RS27225	COG0477	Major facilitator Superfamily
KONIH1_RS27230	COG2982	Protein involved in outer membrane biogenesis
KONIH1_RS27240	COG0612	Peptidase, M16
KONIH1_RS27250	COG2200	EAL domain
KONIH1_RS27250	COG2199	diguanylate cyclase activity
KONIH1_RS27255	COG0457	Tetratricopeptide repeat
KONIH1_RS27255	COG3118	belongs to the thioredoxin family
KONIH1_RS27260	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KONIH1_RS27265	COG1215	transferase activity, transferring glycosyl groups
KONIH1_RS27300	COG2194	sulfuric ester hydrolase activity
KONIH1_RS27330	COG0457	Tetratricopeptide repeat
KONIH1_RS27345	COG0489	protein tyrosine kinase activity
KONIH1_RS27355	COG4608	Belongs to the ABC transporter superfamily
KONIH1_RS27360	COG0444	Belongs to the ABC transporter superfamily
KONIH1_RS27365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KONIH1_RS27370	COG0601	transmembrane transport
KONIH1_RS27375	COG0747	negative chemotaxis
KONIH1_RS27390	COG2223	nitrite transmembrane transporter activity
KONIH1_RS27395	COG5571	outer membrane autotransporter
KONIH1_RS27400	COG2818	Glycosylase
KONIH1_RS27405	COG0456	acetyltransferase
KONIH1_RS27415	COG2885	chlorophyll binding
KONIH1_RS27420	COG1609	Transcriptional regulator
KONIH1_RS27430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KONIH1_RS27450	COG2814	Major facilitator Superfamily
KONIH1_RS27455	COG2944	sequence-specific DNA binding
KONIH1_RS27460	COG1278	Cold shock
KONIH1_RS27490	COG3274	enterobacterial common antigen metabolic process
KONIH1_RS27495	COG4682	membrane
KONIH1_RS27500	COG1070	Carbohydrate kinase
KONIH1_RS27505	COG2115	Belongs to the xylose isomerase family
KONIH1_RS27510	COG4213	ABC transporter substrate-binding protein
KONIH1_RS27520	COG4214	carbohydrate transport
KONIH1_RS27525	COG2207	Transcriptional regulator
KONIH1_RS27525	COG1609	Transcriptional regulator
KONIH1_RS27530	COG2992	FlgJ-related protein
KONIH1_RS27535	COG0366	Alpha amylase catalytic
KONIH1_RS27540	COG3977	Valine--pyruvate aminotransferase
KONIH1_RS27545	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KONIH1_RS27550	COG1414	Transcriptional regulator
KONIH1_RS27560	COG2731	YhcH YjgK YiaL family protein
KONIH1_RS27575	COG1070	Carbohydrate kinase
KONIH1_RS27580	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KONIH1_RS27585	COG3623	hexulose-6-phosphate isomerase
KONIH1_RS27590	COG0235	Class ii aldolase
KONIH1_RS27595	COG4977	sequence-specific DNA binding
KONIH1_RS27595	COG1917	Cupin 2, conserved barrel domain protein
KONIH1_RS27600	COG2211	Major facilitator Superfamily
KONIH1_RS27610	COG3276	selenocysteine insertion sequence binding
KONIH1_RS27620	COG0625	glutathione transferase activity
KONIH1_RS27625	COG1566	PFAM secretion protein HlyD family protein
KONIH1_RS27645	COG3722	fumarate hydratase activity
KONIH1_RS27665	COG2186	Transcriptional regulator
KONIH1_RS27675	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KONIH1_RS27695	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KONIH1_RS27700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KONIH1_RS27710	COG4942	peptidase
KONIH1_RS27715	COG2861	carbohydrate metabolic process
KONIH1_RS27720	COG0463	Glycosyl transferase, family 2
KONIH1_RS27730	COG0156	8-amino-7-oxononanoate synthase activity
KONIH1_RS27740	COG0859	PFAM glycosyl transferase family 9
KONIH1_RS27745	COG0859	PFAM glycosyl transferase family 9
KONIH1_RS27770	COG0859	PFAM glycosyl transferase family 9
KONIH1_RS27780	COG0438	transferase activity, transferring glycosyl groups
KONIH1_RS27785	COG1216	Glycosyl transferase, family 2
KONIH1_RS27790	COG1519	Transferase
KONIH1_RS27810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KONIH1_RS27815	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KONIH1_RS27825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KONIH1_RS27840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KONIH1_RS27850	COG1561	YicC-like family, N-terminal region
KONIH1_RS27860	COG2860	membrane
KONIH1_RS27880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KONIH1_RS27885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KONIH1_RS27890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KONIH1_RS27895	COG1494	fructose-1,6-bisphosphatase
KONIH1_RS27905	COG3152	Membrane
KONIH1_RS27935	COG3074	FtsZ-dependent cytokinesis
KONIH1_RS27950	COG0786	glutamate:sodium symporter activity
KONIH1_RS27955	COG2233	PERMEase
KONIH1_RS27960	COG2982	Protein involved in outer membrane biogenesis
KONIH1_RS27965	COG1263	PTS System
KONIH1_RS27965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS27970	COG1486	melibiose metabolic process
KONIH1_RS27985	COG1940	carbohydrate kinase activity
KONIH1_RS27990	COG0191	fructose-bisphosphate aldolase activity
KONIH1_RS28000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KONIH1_RS28000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KONIH1_RS28005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KONIH1_RS28010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KONIH1_RS28010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KONIH1_RS28010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KONIH1_RS28015	COG3711	transcriptional antiterminator
KONIH1_RS28020	COG1501	Belongs to the glycosyl hydrolase 31 family
KONIH1_RS28025	COG2211	Major facilitator Superfamily
KONIH1_RS28035	COG0582	viral genome integration into host DNA
KONIH1_RS28110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KONIH1_RS28130	COG1064	alcohol dehydrogenase
KONIH1_RS28140	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KONIH1_RS28155	COG1464	Belongs to the NlpA lipoprotein family
KONIH1_RS28170	COG0583	DNA-binding transcription factor activity
KONIH1_RS28180	COG1309	transcriptional regulator
KONIH1_RS28190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KONIH1_RS28195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KONIH1_RS28205	COG2814	Major facilitator Superfamily
KONIH1_RS28215	COG1263	PTS System
KONIH1_RS28215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KONIH1_RS28230	COG0697	spore germination
KONIH1_RS28240	COG5464	transposase or invertase
KONIH1_RS28250	COG1609	Transcriptional regulator
KONIH1_RS28260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KONIH1_RS28260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KONIH1_RS28265	COG1447	Phosphotransferase system cellobiose-specific component IIA
KONIH1_RS28270	COG4580	involved in the transport of maltose and maltodextrins
KONIH1_RS28295	COG2188	Transcriptional regulator
KONIH1_RS28335	COG2271	Major facilitator Superfamily
KONIH1_RS28345	COG2197	response regulator
KONIH1_RS28350	COG0440	acetolactate synthase activity
KONIH1_RS28355	COG0028	Belongs to the TPP enzyme family
KONIH1_RS28370	COG2814	Major facilitator Superfamily
KONIH1_RS28375	COG0583	DNA-binding transcription factor activity
KONIH1_RS28380	COG2610	gluconate transmembrane transporter activity
KONIH1_RS28390	COG0641	radical SAM
KONIH1_RS28400	COG2149	membrane
KONIH1_RS28415	COG2188	Transcriptional regulator
KONIH1_RS28435	COG5645	(Lipo)protein
KONIH1_RS28440	COG0823	Involved in the tonB-independent uptake of proteins
KONIH1_RS28445	COG2271	Major facilitator Superfamily
KONIH1_RS28455	COG0800	Aldolase
KONIH1_RS28460	COG3734	2-keto-3-deoxy-galactonokinase
KONIH1_RS28465	COG2186	Transcriptional regulator
KONIH1_RS28470	COG0561	phosphatase activity
KONIH1_RS28480	COG0583	DNA-binding transcription factor activity
KONIH1_RS28485	COG0187	DNA topoisomerase II activity
KONIH1_RS28495	COG0592	DNA-directed DNA polymerase activity
KONIH1_RS28520	COG0456	acetyltransferase
KONIH1_RS28535	COG2091	lysine biosynthetic process via aminoadipic acid
KONIH1_RS28540	COG0431	NADPH-dependent FMN reductase
KONIH1_RS28545	COG2252	PERMEase
KONIH1_RS28550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KONIH1_RS28555	COG0363	glucosamine-6-phosphate deaminase activity
KONIH1_RS28560	COG2382	esterase
KONIH1_RS28570	COG3039	Transposase
KONIH1_RS28575	COG0704	Plays a role in the regulation of phosphate uptake
KONIH1_RS28580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KONIH1_RS28585	COG0581	inorganic phosphate transmembrane transporter activity
KONIH1_RS28590	COG0573	inorganic phosphate transmembrane transporter activity
KONIH1_RS28595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KONIH1_RS28600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KONIH1_RS28655	COG3312	ion transport
KONIH1_RS28670	COG0716	FMN binding
KONIH1_RS28675	COG1522	sequence-specific DNA binding
KONIH1_RS28705	COG1129	ABC transporter
KONIH1_RS28710	COG1172	Belongs to the binding-protein-dependent transport system permease family
KONIH1_RS28720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KONIH1_RS28725	COG1609	Transcriptional regulator
KONIH1_RS28730	COG0477	Major facilitator Superfamily
KONIH1_RS28735	COG2186	Transcriptional regulator
KONIH1_RS28755	COG1763	Mo-molybdopterin cofactor biosynthetic process
KONIH1_RS28765	COG3084	Protein conserved in bacteria
KONIH1_RS28770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KONIH1_RS28780	COG0204	Acyl-transferase
KONIH1_RS28815	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KONIH1_RS28815	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KONIH1_RS28870	COG0456	acetyltransferase
KONIH1_RS29200	COG1129	ABC transporter
KONIH1_RS29590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KONIH1_RS29595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KONIH1_RS29685	COG0456	acetyltransferase
KONIH1_RS30015	COG0668	transmembrane transport
KONIH1_RS30170	COG4695	Portal protein
KONIH1_RS30450	COG0583	DNA-binding transcription factor activity
KONIH1_RS30810	COG0191	fructose-bisphosphate aldolase activity
KONIH1_RS31015	COG1454	alcohol dehydrogenase
KONIH1_RS31050	COG2205	protein histidine kinase activity
KONIH1_RS31370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KONIH1_RS31400	COG0527	aspartate kinase activity
KONIH1_RS31400	COG0460	homoserine dehydrogenase
KONIH1_RS31730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KONIH1_RS31795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase