locus-tag	class	description
kpn2146_RS00005	COG0716	FMN binding
kpn2146_RS00010	COG1522	sequence-specific DNA binding
kpn2146_RS00040	COG1129	ABC transporter
kpn2146_RS00045	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS00055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
kpn2146_RS00060	COG1609	Transcriptional regulator
kpn2146_RS00065	COG0477	Major facilitator Superfamily
kpn2146_RS00070	COG2186	Transcriptional regulator
kpn2146_RS00095	COG1763	Mo-molybdopterin cofactor biosynthetic process
kpn2146_RS00105	COG3084	Protein conserved in bacteria
kpn2146_RS00110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
kpn2146_RS00120	COG0204	Acyl-transferase
kpn2146_RS00140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
kpn2146_RS00150	COG3852	Histidine kinase
kpn2146_RS00170	COG1011	Hydrolase
kpn2146_RS00185	COG0456	acetyltransferase
kpn2146_RS00190	COG0657	acetylesterase activity
kpn2146_RS00195	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
kpn2146_RS00210	COG2864	formate dehydrogenase
kpn2146_RS00215	COG0437	4 iron, 4 sulfur cluster binding
kpn2146_RS00220	COG0243	molybdopterin cofactor binding
kpn2146_RS00220	COG3383	formate dehydrogenase (NAD+) activity
kpn2146_RS00225	COG3383	formate dehydrogenase (NAD+) activity
kpn2146_RS00225	COG0243	molybdopterin cofactor binding
kpn2146_RS00240	COG0205	6-phosphofructokinase activity
kpn2146_RS00300	COG2211	Major facilitator Superfamily
kpn2146_RS00310	COG1454	alcohol dehydrogenase
kpn2146_RS00315	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS00320	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS00325	COG1129	ABC transporter
kpn2146_RS00365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
kpn2146_RS00370	COG2258	MOSC domain
kpn2146_RS00375	COG2205	protein histidine kinase activity
kpn2146_RS00380	COG0745	RESPONSE REGULATOR receiver
kpn2146_RS00385	COG3678	ATP-independent chaperone mediated protein folding
kpn2146_RS00405	COG1575	Belongs to the MenA family. Type 1 subfamily
kpn2146_RS00420	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
kpn2146_RS00425	COG1609	Transcriptional regulator
kpn2146_RS00435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
kpn2146_RS00450	COG0626	cystathionine gamma-synthase activity
kpn2146_RS00455	COG0527	aspartate kinase activity
kpn2146_RS00455	COG0460	homoserine dehydrogenase
kpn2146_RS00465	COG0737	Belongs to the 5'-nucleotidase family
kpn2146_RS00475	COG0583	DNA-binding transcription factor activity
kpn2146_RS00485	COG0697	spore germination
kpn2146_RS00490	COG0371	Dehydrogenase
kpn2146_RS00500	COG2207	Transcriptional regulator
kpn2146_RS00505	COG3443	Belongs to the bacterial solute-binding protein 9 family
kpn2146_RS00520	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
kpn2146_RS00535	COG0583	DNA-binding transcription factor activity
kpn2146_RS00610	COG3085	chromosome segregation
kpn2146_RS00630	COG3978	acetolactate synthase activity
kpn2146_RS00645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
kpn2146_RS00650	COG0583	DNA-binding transcription factor activity
kpn2146_RS00660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
kpn2146_RS00665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
kpn2146_RS00675	COG1811	Na channel or pump
kpn2146_RS00700	COG3118	belongs to the thioredoxin family
kpn2146_RS00705	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
kpn2146_RS00710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
kpn2146_RS00720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
kpn2146_RS00725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
kpn2146_RS00730	COG1088	dTDP-glucose 4,6-dehydratase activity
kpn2146_RS00735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
kpn2146_RS00740	COG0456	acetyltransferase
kpn2146_RS00745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
kpn2146_RS00750	COG2244	polysaccharide biosynthetic process
kpn2146_RS00800	COG3071	HemY protein
kpn2146_RS00805	COG2959	enzyme of heme biosynthesis
kpn2146_RS00825	COG3072	Adenylate cyclase
kpn2146_RS00855	COG1011	Hydrolase
kpn2146_RS00860	COG0210	DNA helicase
kpn2146_RS00895	COG1280	lysine exporter protein (LysE YggA)
kpn2146_RS00905	COG1280	lysine exporter protein (LysE YggA)
kpn2146_RS00910	COG2267	carboxylic ester hydrolase activity
kpn2146_RS00915	COG0561	phosphatase activity
kpn2146_RS00920	COG0697	spore germination
kpn2146_RS00925	COG0583	DNA-binding transcription factor activity
kpn2146_RS00955	COG3165	ubiquinone biosynthetic process from chorismate
kpn2146_RS00975	COG0805	protein transport
kpn2146_RS01020	COG1739	Uncharacterized protein family UPF0029
kpn2146_RS01030	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
kpn2146_RS01060	COG0812	UDP-N-acetylmuramate dehydrogenase activity
kpn2146_RS01105	COG0250	Participates in transcription elongation, termination and antitermination
kpn2146_RS01140	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
kpn2146_RS01145	COG1447	Phosphotransferase system cellobiose-specific component IIA
kpn2146_RS01155	COG3706	GGDEF domain
kpn2146_RS01175	COG2104	thiamine diphosphate biosynthetic process
kpn2146_RS01180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
kpn2146_RS01195	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
kpn2146_RS01230	COG3678	ATP-independent chaperone mediated protein folding
kpn2146_RS01240	COG4191	Histidine kinase
kpn2146_RS01250	COG0151	Belongs to the GarS family
kpn2146_RS01290	COG0456	acetyltransferase
kpn2146_RS01300	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
kpn2146_RS01330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
kpn2146_RS01385	COG0527	aspartate kinase activity
kpn2146_RS01395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
kpn2146_RS01405	COG0251	oxidation-reduction process
kpn2146_RS01480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
kpn2146_RS01490	COG0534	Mate efflux family protein
kpn2146_RS01500	COG3237	CsbD-like
kpn2146_RS01505	COG0735	belongs to the Fur family
kpn2146_RS01520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
kpn2146_RS01535	COG0305	Participates in initiation and elongation during chromosome replication
kpn2146_RS01540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
kpn2146_RS01555	COG0432	Pfam Uncharacterised protein family UPF0047
kpn2146_RS01560	COG2315	Protein conserved in bacteria
kpn2146_RS01575	COG0741	lytic transglycosylase activity
kpn2146_RS01585	COG4771	TonB-dependent receptor
kpn2146_RS01610	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
kpn2146_RS01620	COG0483	inositol monophosphate 1-phosphatase activity
kpn2146_RS01625	COG1609	Transcriptional regulator
kpn2146_RS01630	COG1234	tRNA 3'-trailer cleavage
kpn2146_RS01660	COG4943	cyclic-guanylate-specific phosphodiesterase activity
kpn2146_RS01670	COG0789	Transcriptional regulator
kpn2146_RS01675	COG0625	glutathione transferase activity
kpn2146_RS01680	COG2252	PERMEase
kpn2146_RS01685	COG0025	NhaP-type Na H and K H
kpn2146_RS01690	COG0583	DNA-binding transcription factor activity
kpn2146_RS01695	COG1380	Effector of murein hydrolase LrgA
kpn2146_RS01700	COG1346	cytolysis
kpn2146_RS01710	COG3539	Fimbrial protein
kpn2146_RS01740	COG3162	membrane
kpn2146_RS01750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
kpn2146_RS01760	COG1301	dicarboxylic acid transport
kpn2146_RS01765	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
kpn2146_RS01770	COG3383	formate dehydrogenase (NAD+) activity
kpn2146_RS01775	COG3383	formate dehydrogenase (NAD+) activity
kpn2146_RS01810	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS01815	COG1129	ABC transporter
kpn2146_RS01820	COG4191	Histidine kinase
kpn2146_RS01820	COG0784	Response regulator, receiver
kpn2146_RS01830	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
kpn2146_RS01840	COG3454	Phosphonate metabolism
kpn2146_RS01845	COG4778	phosphonate C-P lyase system protein PhnL
kpn2146_RS01850	COG4107	phosphonate C-P lyase system protein PhnK
kpn2146_RS01855	COG3627	carbon phosphorus lyase activity
kpn2146_RS01860	COG3626	phosphonate metabolism
kpn2146_RS01865	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
kpn2146_RS01870	COG3624	Phosphonate C-P lyase system protein PhnG
kpn2146_RS01875	COG2188	Transcriptional regulator
kpn2146_RS01880	COG2764	glyoxalase bleomycin resistance protein dioxygenase
kpn2146_RS01885	COG2824	Alkylphosphonate utilization operon protein PhnA
kpn2146_RS01900	COG2169	Transcriptional regulator
kpn2146_RS01905	COG1486	melibiose metabolic process
kpn2146_RS01930	COG2801	Transposase and inactivated derivatives
kpn2146_RS01955	COG0861	Integral membrane protein TerC family
kpn2146_RS01975	COG1215	transferase activity, transferring glycosyl groups
kpn2146_RS01980	COG1649	PFAM Uncharacterised BCR, COG1649
kpn2146_RS01980	COG0726	polysaccharide deacetylase
kpn2146_RS01985	COG0457	Tetratricopeptide repeat
kpn2146_RS02020	COG1309	transcriptional regulator
kpn2146_RS02035	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
kpn2146_RS02040	COG1027	Aspartate ammonia-lyase
kpn2146_RS02050	COG3030	protein affecting phage T7 exclusion by the F plasmid
kpn2146_RS02055	COG0531	amino acid
kpn2146_RS02130	COG1509	lysine 2,3-aminomutase activity
kpn2146_RS02145	COG5510	response to toxic substance
kpn2146_RS02150	COG2076	Multidrug Resistance protein
kpn2146_RS02170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
kpn2146_RS02175	COG1053	succinate dehydrogenase
kpn2146_RS02190	COG3264	Mechanosensitive ion channel
kpn2146_RS02190	COG1511	domain protein
kpn2146_RS02210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
kpn2146_RS02230	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
kpn2146_RS02235	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
kpn2146_RS02235	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
kpn2146_RS02240	COG0802	atpase or kinase
kpn2146_RS02245	COG0860	N-Acetylmuramoyl-L-alanine amidase
kpn2146_RS02265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
kpn2146_RS02270	COG0330	HflC and HflK could
kpn2146_RS02275	COG0330	HflC and HflK could
kpn2146_RS02290	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
kpn2146_RS02305	COG0557	exoribonuclease II activity
kpn2146_RS02310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
kpn2146_RS02315	COG1960	acyl-CoA dehydrogenase activity
kpn2146_RS02325	COG3650	response to hydrogen peroxide
kpn2146_RS02330	COG1073	alpha beta
kpn2146_RS02390	COG2965	DNA replication, synthesis of RNA primer
kpn2146_RS02395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
kpn2146_RS02405	COG3061	Opacity-associated protein A
kpn2146_RS02410	COG0545	Peptidyl-prolyl cis-trans isomerase
kpn2146_RS02415	COG1113	amino acid transport
kpn2146_RS02425	COG0697	spore germination
kpn2146_RS02435	COG0702	epimerase
kpn2146_RS02440	COG1733	regulation of RNA biosynthetic process
kpn2146_RS02455	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
kpn2146_RS02470	COG1253	flavin adenine dinucleotide binding
kpn2146_RS02480	COG0729	surface antigen
kpn2146_RS02485	COG2911	Protein conserved in bacteria
kpn2146_RS02490	COG2105	PFAM AIG2 family protein
kpn2146_RS02510	COG1879	ABC-type sugar transport system periplasmic component
kpn2146_RS02520	COG1129	ABC transporter
kpn2146_RS02525	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS02530	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS02540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
kpn2146_RS02565	COG0312	modulator of DNA gyrase
kpn2146_RS02605	COG3964	amidohydrolase
kpn2146_RS02620	COG2706	6-phosphogluconolactonase activity
kpn2146_RS02625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS02625	COG3711	transcriptional antiterminator
kpn2146_RS02630	COG3077	Addiction module antitoxin, RelB DinJ family
kpn2146_RS02635	COG2026	Addiction module toxin, RelE StbE family
kpn2146_RS02640	COG0602	queuosine metabolic process
kpn2146_RS02670	COG1486	melibiose metabolic process
kpn2146_RS02675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
kpn2146_RS02680	COG0366	Alpha amylase catalytic
kpn2146_RS02685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
kpn2146_RS02685	COG1263	PTS System
kpn2146_RS02715	COG2731	YhcH YjgK YiaL family protein
kpn2146_RS02725	COG2222	sugar isomerase
kpn2146_RS02730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
kpn2146_RS02735	COG1228	amidohydrolase
kpn2146_RS02740	COG1288	antiporter activity
kpn2146_RS02745	COG2188	Transcriptional regulator
kpn2146_RS02770	COG0525	valine-tRNA ligase activity
kpn2146_RS02775	COG2927	DNA polymerase III (CHI subunit)
kpn2146_RS02785	COG0795	lipopolysaccharide-transporting ATPase activity
kpn2146_RS02790	COG0795	lipopolysaccharide-transporting ATPase activity
kpn2146_RS02795	COG0433	COG0433 Predicted ATPase
kpn2146_RS02810	COG3718	enzyme involved in inositol metabolism
kpn2146_RS02830	COG1737	Transcriptional regulator
kpn2146_RS02830	COG0837	glucose binding
kpn2146_RS02835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
kpn2146_RS02845	COG3962	Belongs to the TPP enzyme family
kpn2146_RS02855	COG1082	Xylose isomerase domain protein TIM barrel
kpn2146_RS02865	COG1653	transport
kpn2146_RS02870	COG3842	ATPase activity
kpn2146_RS02875	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
kpn2146_RS02880	COG0395	ABC-type sugar transport system, permease component
kpn2146_RS02885	COG1175	transmembrane transport
kpn2146_RS02890	COG1064	alcohol dehydrogenase
kpn2146_RS02895	COG0659	secondary active sulfate transmembrane transporter activity
kpn2146_RS02900	COG0288	reversible hydration of carbon dioxide
kpn2146_RS02910	COG0582	viral genome integration into host DNA
kpn2146_RS03010	COG0582	viral genome integration into host DNA
kpn2146_RS03070	COG2963	transposase activity
kpn2146_RS03080	COG2801	Transposase and inactivated derivatives
kpn2146_RS03085	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
kpn2146_RS03085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
kpn2146_RS03125	COG3507	Belongs to the glycosyl hydrolase 43 family
kpn2146_RS03130	COG2211	Major facilitator Superfamily
kpn2146_RS03145	COG4580	involved in the transport of maltose and maltodextrins
kpn2146_RS03150	COG3272	Protein of unknown function (DUF1722)
kpn2146_RS03170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
kpn2146_RS03185	COG0300	oxidoreductase activity
kpn2146_RS03195	COG0789	Transcriptional regulator
kpn2146_RS03200	COG3040	lipid binding
kpn2146_RS03210	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
kpn2146_RS03215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
kpn2146_RS03220	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
kpn2146_RS03225	COG1538	Outer membrane efflux protein
kpn2146_RS03235	COG0745	RESPONSE REGULATOR receiver
kpn2146_RS03240	COG5002	protein histidine kinase activity
kpn2146_RS03255	COG2850	peptidyl-arginine hydroxylation
kpn2146_RS03290	COG0842	Transport permease protein
kpn2146_RS03295	COG0842	Transport permease protein
kpn2146_RS03295	COG1129	ABC transporter
kpn2146_RS03300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
kpn2146_RS03310	COG1879	ABC-type sugar transport system periplasmic component
kpn2146_RS03315	COG1129	ABC transporter
kpn2146_RS03320	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS03330	COG2249	NAD(P)H dehydrogenase (quinone) activity
kpn2146_RS03335	COG0583	DNA-binding transcription factor activity
kpn2146_RS03345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
kpn2146_RS03350	COG5457	Domain of unknown function (DUF1127)
kpn2146_RS03360	COG1566	PFAM secretion protein HlyD family protein
kpn2146_RS03375	COG1924	4 iron, 4 sulfur cluster binding
kpn2146_RS03380	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
kpn2146_RS03395	COG2733	membrane
kpn2146_RS03405	COG2207	Transcriptional regulator
kpn2146_RS03405	COG1917	Cupin 2, conserved barrel domain protein
kpn2146_RS03410	COG5464	transposase or invertase
kpn2146_RS03415	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS03425	COG0523	cobalamin synthesis protein
kpn2146_RS03430	COG2879	small protein
kpn2146_RS03435	COG1966	Carbon starvation protein
kpn2146_RS03450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
kpn2146_RS03455	COG2368	4-hydroxyphenylacetate
kpn2146_RS03475	COG3971	2-oxopent-4-enoate hydratase activity
kpn2146_RS03485	COG3384	dioxygenase
kpn2146_RS03490	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS03500	COG0179	Fumarylacetoacetate (FAA) hydrolase
kpn2146_RS03510	COG1846	Transcriptional regulator
kpn2146_RS03540	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
kpn2146_RS03555	COG3734	2-keto-3-deoxy-galactonokinase
kpn2146_RS03560	COG0800	Aldolase
kpn2146_RS03565	COG1737	Transcriptional regulator
kpn2146_RS03575	COG1214	PFAM Peptidase M22, glycoprotease
kpn2146_RS03575	COG0456	acetyltransferase
kpn2146_RS03580	COG2271	Major facilitator Superfamily
kpn2146_RS03585	COG1802	Transcriptional regulator
kpn2146_RS03590	COG1063	alcohol dehydrogenase
kpn2146_RS03600	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
kpn2146_RS03600	COG3933	PFAM sigma-54 factor interaction domain-containing protein
kpn2146_RS03615	COG3715	PTS system
kpn2146_RS03620	COG3716	PTS system mannose fructose sorbose family IID component
kpn2146_RS03625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
kpn2146_RS03635	COG5464	transposase or invertase
kpn2146_RS03650	COG1484	DNA-dependent DNA replication
kpn2146_RS03665	COG2966	Psort location CytoplasmicMembrane, score
kpn2146_RS03685	COG2197	response regulator
kpn2146_RS03690	COG2197	response regulator
kpn2146_RS03695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
kpn2146_RS03700	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
kpn2146_RS03700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
kpn2146_RS03705	COG4114	ferric iron reductase
kpn2146_RS03710	COG3706	GGDEF domain
kpn2146_RS03745	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
kpn2146_RS03750	COG0456	acetyltransferase
kpn2146_RS03755	COG1011	Hydrolase
kpn2146_RS03765	COG2823	Periplasmic or secreted lipoprotein
kpn2146_RS03775	COG4667	esterase of the alpha-beta hydrolase superfamily
kpn2146_RS03780	COG0084	hydrolase, TatD family'
kpn2146_RS03785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
kpn2146_RS03815	COG3726	membrane protein affecting hemolysin expression
kpn2146_RS03820	COG0560	Phosphoserine phosphatase
kpn2146_RS03825	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
kpn2146_RS03835	COG0488	(ABC) transporter
kpn2146_RS03840	COG0741	lytic transglycosylase activity
kpn2146_RS03860	COG3708	Transcriptional regulator
kpn2146_RS03860	COG2207	Transcriptional regulator
kpn2146_RS03865	COG3045	CreA protein
kpn2146_RS03870	COG0745	RESPONSE REGULATOR receiver
kpn2146_RS03875	COG2205	protein histidine kinase activity
kpn2146_RS03880	COG4452	Inner membrane protein CreD
kpn2146_RS03885	COG0745	RESPONSE REGULATOR receiver
kpn2146_RS03890	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
kpn2146_RS03900	COG0460	homoserine dehydrogenase
kpn2146_RS03900	COG0527	aspartate kinase activity
kpn2146_RS03910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
kpn2146_RS03925	COG1115	amino acid carrier protein
kpn2146_RS03930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
kpn2146_RS03935	COG0521	Mo-molybdopterin cofactor biosynthetic process
kpn2146_RS03940	COG0477	Major facilitator Superfamily
kpn2146_RS03945	COG1584	GPR1 FUN34 yaaH family protein
kpn2146_RS03950	COG4735	regulation of single-species biofilm formation
kpn2146_RS03975	COG0583	DNA-binding transcription factor activity
kpn2146_RS03990	COG0196	riboflavin kinase activity
kpn2146_RS04005	COG1047	Peptidyl-prolyl cis-trans
kpn2146_RS04030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
kpn2146_RS04105	COG0505	Belongs to the CarA family
kpn2146_RS04150	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
kpn2146_RS04160	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
kpn2146_RS04165	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
kpn2146_RS04180	COG3493	citrate carrier protein
kpn2146_RS04195	COG0564	pseudouridine synthase activity
kpn2146_RS04205	COG0417	DNA replication proofreading
kpn2146_RS04210	COG0235	Class ii aldolase
kpn2146_RS04235	COG0586	Pfam SNARE associated Golgi protein
kpn2146_RS04245	COG1178	ABC-type Fe3 transport system permease component
kpn2146_RS04270	COG2814	Major facilitator Superfamily
kpn2146_RS04275	COG2271	Major facilitator Superfamily
kpn2146_RS04280	COG0583	DNA-binding transcription factor activity
kpn2146_RS04290	COG0738	Major facilitator superfamily
kpn2146_RS04335	COG0028	Belongs to the TPP enzyme family
kpn2146_RS04345	COG1609	Transcriptional regulator
kpn2146_RS04365	COG0768	penicillin binding
kpn2146_RS04370	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
kpn2146_RS04375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
kpn2146_RS04390	COG0772	Belongs to the SEDS family
kpn2146_RS04415	COG0849	cell division
kpn2146_RS04420	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
kpn2146_RS04440	COG0494	nUDIX hydrolase
kpn2146_RS04470	COG1459	type II secretion system
kpn2146_RS04475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
kpn2146_RS04480	COG4969	Belongs to the N-Me-Phe pilin family
kpn2146_RS04490	COG3023	N-Acetylmuramoyl-L-alanine amidase
kpn2146_RS04495	COG3725	Membrane protein required for beta-lactamase induction
kpn2146_RS04500	COG3940	Belongs to the glycosyl hydrolase 43 family
kpn2146_RS04505	COG2211	Major facilitator Superfamily
kpn2146_RS04510	COG1113	amino acid transport
kpn2146_RS04520	COG2186	Transcriptional regulator
kpn2146_RS04525	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
kpn2146_RS04530	COG0508	dehydrogenase complex catalyzes the overall conversion of
kpn2146_RS04535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
kpn2146_RS04550	COG3064	Membrane
kpn2146_RS04610	COG2132	Multicopper oxidase
kpn2146_RS04615	COG4993	Dehydrogenase
kpn2146_RS04630	COG0288	reversible hydration of carbon dioxide
kpn2146_RS04635	COG1131	(ABC) transporter
kpn2146_RS04640	COG0842	Transport permease protein
kpn2146_RS04645	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS04650	COG0726	polysaccharide deacetylase
kpn2146_RS04670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
kpn2146_RS04675	COG0617	tRNA 3'-terminal CCA addition
kpn2146_RS04695	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
kpn2146_RS04700	COG1643	Atp-dependent helicase
kpn2146_RS04800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
kpn2146_RS04805	COG4774	siderophore transport
kpn2146_RS04810	COG1120	ATPase activity
kpn2146_RS04815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
kpn2146_RS04820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
kpn2146_RS04840	COG2860	membrane
kpn2146_RS04860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
kpn2146_RS04865	COG3835	regulator
kpn2146_RS04880	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
kpn2146_RS04885	COG0024	Methionine aminopeptidase
kpn2146_RS04910	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
kpn2146_RS04920	COG0575	Belongs to the CDS family
kpn2146_RS04925	COG0750	zinc metalloprotease
kpn2146_RS04935	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
kpn2146_RS04975	COG1982	Orn Lys Arg decarboxylase major
kpn2146_RS04980	COG0346	lactoylglutathione lyase activity
kpn2146_RS04990	COG4568	rho-dependent transcription termination
kpn2146_RS05005	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
kpn2146_RS05010	COG3015	lipoprotein NlpE involved in copper resistance
kpn2146_RS05015	COG0791	NLP P60 protein
kpn2146_RS05025	COG1720	tRNA m6t6A37 methyltransferase activity
kpn2146_RS05035	COG1464	Belongs to the NlpA lipoprotein family
kpn2146_RS05040	COG2011	ABC-type metal ion transport system permease component
kpn2146_RS05050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
kpn2146_RS05085	COG0656	L-ascorbic acid biosynthetic process
kpn2146_RS05090	COG0583	DNA-binding transcription factor activity
kpn2146_RS05095	COG2814	Major facilitator Superfamily
kpn2146_RS05105	COG2226	methyltransferase
kpn2146_RS05110	COG1388	LysM domain
kpn2146_RS05110	COG0741	lytic transglycosylase activity
kpn2146_RS05120	COG2226	methyltransferase
kpn2146_RS05130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
kpn2146_RS05140	COG0583	DNA-binding transcription factor activity
kpn2146_RS05150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
kpn2146_RS05155	COG1960	acyl-CoA dehydrogenase activity
kpn2146_RS05165	COG0121	glutamine amidotransferase
kpn2146_RS05170	COG3034	peptidoglycan biosynthetic process
kpn2146_RS05190	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
kpn2146_RS05195	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
kpn2146_RS05210	COG2991	Protein conserved in bacteria
kpn2146_RS05225	COG0454	-acetyltransferase
kpn2146_RS05230	COG2195	Cleaves the N-terminal amino acid of tripeptides
kpn2146_RS05250	COG1802	Transcriptional regulator
kpn2146_RS05255	COG1113	amino acid transport
kpn2146_RS05260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
kpn2146_RS05265	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS05270	COG0579	oxidoreductase
kpn2146_RS05285	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
kpn2146_RS05290	COG0625	glutathione transferase activity
kpn2146_RS05295	COG3775	system Galactitol-specific IIC component
kpn2146_RS05300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
kpn2146_RS05305	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS05310	COG1070	Carbohydrate kinase
kpn2146_RS05330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
kpn2146_RS05335	COG0508	dehydrogenase complex catalyzes the overall conversion of
kpn2146_RS05340	COG0022	dehydrogenase e1 component
kpn2146_RS05345	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
kpn2146_RS05380	COG0791	NLP P60 protein
kpn2146_RS05400	COG3639	organic phosphonate transmembrane transporter activity
kpn2146_RS05410	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
kpn2146_RS05435	COG3188	usher protein
kpn2146_RS05450	COG0765	amino acid transport
kpn2146_RS05455	COG0765	amino acid transport
kpn2146_RS05460	COG1126	abc transporter atp-binding protein
kpn2146_RS05465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
kpn2146_RS05505	COG4302	ethanolamine ammonia-lyase activity
kpn2146_RS05510	COG4303	Ethanolamine ammonia lyase large subunit
kpn2146_RS05525	COG0833	amino acid
kpn2146_RS05530	COG2040	homocysteine
kpn2146_RS05535	COG4521	taurine ABC transporter
kpn2146_RS05540	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
kpn2146_RS05545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
kpn2146_RS05550	COG2175	clavaminate synthase activity
kpn2146_RS05560	COG0113	porphobilinogen synthase activity
kpn2146_RS05565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
kpn2146_RS05570	COG1335	isochorismatase
kpn2146_RS05575	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
kpn2146_RS05615	COG1785	Belongs to the alkaline phosphatase family
kpn2146_RS05625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
kpn2146_RS05635	COG3416	Protein conserved in bacteria
kpn2146_RS05640	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
kpn2146_RS05650	COG4126	flavin adenine dinucleotide binding
kpn2146_RS05665	COG1940	carbohydrate kinase activity
kpn2146_RS05670	COG0419	ATPase involved in DNA repair
kpn2146_RS05675	COG0420	3'-5' exonuclease activity
kpn2146_RS05700	COG0366	Alpha amylase catalytic
kpn2146_RS05705	COG0583	DNA-binding transcription factor activity
kpn2146_RS05710	COG1335	isochorismatase
kpn2146_RS05720	COG1228	amidohydrolase
kpn2146_RS05730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
kpn2146_RS05745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS05755	COG0450	alkyl hydroperoxide reductase
kpn2146_RS05780	COG1862	Preprotein translocase
kpn2146_RS05785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
kpn2146_RS05790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
kpn2146_RS05810	COG4238	major outer membrane lipoprotein
kpn2146_RS05820	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
kpn2146_RS05820	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
kpn2146_RS05840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
kpn2146_RS05845	COG0667	Aldo Keto reductase
kpn2146_RS05855	COG0142	geranyltranstransferase activity
kpn2146_RS05875	COG0693	protein deglycase activity
kpn2146_RS05880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
kpn2146_RS05890	COG2814	Major facilitator Superfamily
kpn2146_RS05895	COG0673	inositol 2-dehydrogenase activity
kpn2146_RS05910	COG1053	succinate dehydrogenase
kpn2146_RS05920	COG1053	succinate dehydrogenase
kpn2146_RS05925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
kpn2146_RS05930	COG1414	Transcriptional regulator
kpn2146_RS05945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
kpn2146_RS05950	COG1845	cytochrome c oxidase, subunit III
kpn2146_RS05955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
kpn2146_RS05960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
kpn2146_RS05965	COG2223	nitrite transmembrane transporter activity
kpn2146_RS05970	COG3056	Lipoprotein
kpn2146_RS05975	COG0271	Belongs to the BolA IbaG family
kpn2146_RS05995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
kpn2146_RS06000	COG0776	regulation of translation
kpn2146_RS06005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
kpn2146_RS06010	COG1555	photosystem II stabilization
kpn2146_RS06015	COG0824	Thioesterase
kpn2146_RS06025	COG4533	DNA binding
kpn2146_RS06040	COG1522	sequence-specific DNA binding
kpn2146_RS06045	COG1132	(ABC) transporter
kpn2146_RS06050	COG1132	(ABC) transporter
kpn2146_RS06055	COG0347	Belongs to the P(II) protein family
kpn2146_RS06060	COG0004	ammonium transporteR
kpn2146_RS06065	COG1946	Acyl-CoA thioesterase
kpn2146_RS06070	COG3126	Type III secretion system lipoprotein chaperone (YscW)
kpn2146_RS06075	COG3695	enzyme binding
kpn2146_RS06105	COG2364	Membrane
kpn2146_RS06120	COG4943	cyclic-guanylate-specific phosphodiesterase activity
kpn2146_RS06135	COG2182	Extracellular solute-binding protein
kpn2146_RS06140	COG1175	transmembrane transport
kpn2146_RS06145	COG3833	ABC-type maltose transport systems, permease component
kpn2146_RS06150	COG3867	Arabinogalactan endo-beta-1,4-galactanase
kpn2146_RS06155	COG1874	Beta-galactosidase
kpn2146_RS06205	COG0110	maltose O-acetyltransferase activity
kpn2146_RS06220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
kpn2146_RS06225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
kpn2146_RS06230	COG1309	transcriptional regulator
kpn2146_RS06235	COG1196	nuclear chromosome segregation
kpn2146_RS06235	COG3264	Mechanosensitive ion channel
kpn2146_RS06240	COG5464	transposase or invertase
kpn2146_RS06250	COG3923	Primosomal replication protein n
kpn2146_RS06255	COG2832	Protein of unknown function (DUF454)
kpn2146_RS06295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
kpn2146_RS06300	COG4651	solute:proton antiporter activity
kpn2146_RS06300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
kpn2146_RS06315	COG2223	nitrite transmembrane transporter activity
kpn2146_RS06325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
kpn2146_RS06330	COG3735	TraB family
kpn2146_RS06345	COG1585	Membrane protein implicated in regulation of membrane protease activity
kpn2146_RS06350	COG0330	HflC and HflK could
kpn2146_RS06355	COG4619	ABC transporter
kpn2146_RS06360	COG0390	transport system, permease component
kpn2146_RS06365	COG3118	belongs to the thioredoxin family
kpn2146_RS06370	COG0300	oxidoreductase activity
kpn2146_RS06375	COG2755	lipolytic protein G-D-S-L family
kpn2146_RS06380	COG4181	ATPase activity
kpn2146_RS06385	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
kpn2146_RS06405	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
kpn2146_RS06410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
kpn2146_RS06425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
kpn2146_RS06435	COG2501	S4 domain
kpn2146_RS06450	COG0582	viral genome integration into host DNA
kpn2146_RS06525	COG0305	Participates in initiation and elongation during chromosome replication
kpn2146_RS06585	COG3772	lysozyme
kpn2146_RS06765	COG3344	reverse transcriptase
kpn2146_RS06815	COG3539	Fimbrial protein
kpn2146_RS06820	COG3121	Chaperone
kpn2146_RS06825	COG3188	usher protein
kpn2146_RS06840	COG1560	Kdo2-lipid A biosynthetic process
kpn2146_RS06850	COG3710	Transcriptional regulator
kpn2146_RS06855	COG0531	amino acid
kpn2146_RS06860	COG1982	Orn Lys Arg decarboxylase major
kpn2146_RS06865	COG3104	oligopeptide transport
kpn2146_RS06895	COG0673	inositol 2-dehydrogenase activity
kpn2146_RS06910	COG1129	ABC transporter
kpn2146_RS06915	COG4211	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS06970	COG1566	PFAM secretion protein HlyD family protein
kpn2146_RS06975	COG1120	ATPase activity
kpn2146_RS06980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
kpn2146_RS07015	COG1473	amidohydrolase
kpn2146_RS07020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
kpn2146_RS07025	COG0667	Aldo Keto reductase
kpn2146_RS07070	COG0531	amino acid
kpn2146_RS07080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
kpn2146_RS07085	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS07100	COG1113	amino acid transport
kpn2146_RS07105	COG2211	Major facilitator Superfamily
kpn2146_RS07115	COG0673	inositol 2-dehydrogenase activity
kpn2146_RS07130	COG2771	luxR family
kpn2146_RS07145	COG3188	usher protein
kpn2146_RS07180	COG0668	transmembrane transport
kpn2146_RS07185	COG0477	Major facilitator Superfamily
kpn2146_RS07200	COG3933	PFAM sigma-54 factor interaction domain-containing protein
kpn2146_RS07200	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
kpn2146_RS07205	COG2222	sugar isomerase
kpn2146_RS07210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
kpn2146_RS07215	COG3716	PTS system mannose fructose sorbose family IID component
kpn2146_RS07225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
kpn2146_RS07235	COG0778	Nitroreductase
kpn2146_RS07240	COG2315	Protein conserved in bacteria
kpn2146_RS07305	COG2801	Transposase and inactivated derivatives
kpn2146_RS07310	COG3698	Phosphodiester glycosidase
kpn2146_RS07320	COG0697	spore germination
kpn2146_RS07335	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
kpn2146_RS07340	COG0765	amino acid transport
kpn2146_RS07345	COG4215	(ABC) transporter
kpn2146_RS07355	COG4221	oxidoreductase activity
kpn2146_RS07360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
kpn2146_RS07370	COG4608	Belongs to the ABC transporter superfamily
kpn2146_RS07375	COG0444	Belongs to the ABC transporter superfamily
kpn2146_RS07380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
kpn2146_RS07385	COG0601	transmembrane transport
kpn2146_RS07390	COG0747	negative chemotaxis
kpn2146_RS07415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
kpn2146_RS07425	COG0668	transmembrane transport
kpn2146_RS07430	COG0583	DNA-binding transcription factor activity
kpn2146_RS07445	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS07455	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS07460	COG1129	ABC transporter
kpn2146_RS07470	COG1879	ABC-type sugar transport system periplasmic component
kpn2146_RS07475	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
kpn2146_RS07480	COG2390	Transcriptional regulator
kpn2146_RS07485	COG3959	Transketolase, thiamine diphosphate binding domain
kpn2146_RS07490	COG3958	Transketolase
kpn2146_RS07495	COG2977	Belongs to the P-Pant transferase superfamily
kpn2146_RS07500	COG4771	TonB-dependent receptor
kpn2146_RS07505	COG2382	esterase
kpn2146_RS07510	COG3251	PFAM MbtH domain protein
kpn2146_RS07515	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
kpn2146_RS07515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
kpn2146_RS07520	COG1120	ATPase activity
kpn2146_RS07525	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
kpn2146_RS07530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
kpn2146_RS07540	COG4592	Periplasmic binding protein
kpn2146_RS07545	COG1169	isochorismate synthase
kpn2146_RS07550	COG1021	2,3-dihydroxybenzoate-AMP ligase
kpn2146_RS07555	COG1535	isochorismatase
kpn2146_RS07555	COG3433	isochorismatase activity
kpn2146_RS07560	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS07570	COG1966	Carbon starvation protein
kpn2146_RS07575	COG2879	small protein
kpn2146_RS07590	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS07595	COG0371	Dehydrogenase
kpn2146_RS07600	COG1129	ABC transporter
kpn2146_RS07605	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS07635	COG2271	Major facilitator Superfamily
kpn2146_RS07640	COG0483	inositol monophosphate 1-phosphatase activity
kpn2146_RS07650	COG0402	S-adenosylhomocysteine deaminase activity
kpn2146_RS07660	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
kpn2146_RS07675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
kpn2146_RS07685	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS07690	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS07695	COG1129	ABC transporter
kpn2146_RS07720	COG0436	Aminotransferase
kpn2146_RS07725	COG1475	DNA binding
kpn2146_RS07730	COG3969	phosphoadenosine phosphosulfate
kpn2146_RS07735	COG0583	DNA-binding transcription factor activity
kpn2146_RS07740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
kpn2146_RS07760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
kpn2146_RS07765	COG3719	Belongs to the RNase T2 family
kpn2146_RS07770	COG3069	C4-dicarboxylate transmembrane transporter activity
kpn2146_RS07790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
kpn2146_RS07805	COG0583	DNA-binding transcription factor activity
kpn2146_RS07820	COG1686	Belongs to the peptidase S11 family
kpn2146_RS07825	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
kpn2146_RS07830	COG0772	Belongs to the SEDS family
kpn2146_RS07835	COG0768	penicillin binding
kpn2146_RS07845	COG0799	negative regulation of ribosome biogenesis
kpn2146_RS07860	COG1466	dna polymerase III delta subunit
kpn2146_RS07875	COG2888	peptidyl-tyrosine sulfation
kpn2146_RS07895	COG1126	abc transporter atp-binding protein
kpn2146_RS07900	COG0765	amino acid transport
kpn2146_RS07905	COG0765	amino acid transport
kpn2146_RS07920	COG4535	Mg2 and Co2 transporter CorC
kpn2146_RS07930	COG1702	phosphate starvation-inducible protein PhoH
kpn2146_RS07940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
kpn2146_RS07980	COG0367	asparagine synthase
kpn2146_RS07985	COG0647	UMP catabolic process
kpn2146_RS07990	COG1940	carbohydrate kinase activity
kpn2146_RS07990	COG1846	Transcriptional regulator
kpn2146_RS07995	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
kpn2146_RS08035	COG0735	belongs to the Fur family
kpn2146_RS08050	COG0596	Alpha beta hydrolase
kpn2146_RS08065	COG0033	Phosphoglucomutase
kpn2146_RS08075	COG0745	RESPONSE REGULATOR receiver
kpn2146_RS08080	COG2205	protein histidine kinase activity
kpn2146_RS08105	COG0415	Belongs to the DNA photolyase family
kpn2146_RS08120	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
kpn2146_RS08125	COG1984	allophanate hydrolase subunit 2
kpn2146_RS08165	COG2009	succinate dehydrogenase
kpn2146_RS08170	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
kpn2146_RS08175	COG1053	succinate dehydrogenase
kpn2146_RS08180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
kpn2146_RS08185	COG0567	Dehydrogenase, E1 component
kpn2146_RS08190	COG0508	dehydrogenase complex catalyzes the overall conversion of
kpn2146_RS08200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
kpn2146_RS08210	COG1271	oxidase subunit
kpn2146_RS08215	COG1294	oxidase, subunit
kpn2146_RS08220	COG4890	Cyd operon protein YbgT
kpn2146_RS08225	COG3790	cyd operon protein YbgE
kpn2146_RS08230	COG0824	Thioesterase
kpn2146_RS08235	COG0811	peptide transport
kpn2146_RS08240	COG0848	biopolymer transport protein
kpn2146_RS08245	COG3064	Membrane
kpn2146_RS08255	COG2885	chlorophyll binding
kpn2146_RS08260	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
kpn2146_RS08325	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
kpn2146_RS08330	COG3201	nicotinamide mononucleotide transporter
kpn2146_RS08345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
kpn2146_RS08355	COG2017	converts alpha-aldose to the beta-anomer
kpn2146_RS08365	COG1085	galactose-1-phosphate uridylyltransferase
kpn2146_RS08380	COG1119	ATPase activity
kpn2146_RS08385	COG3585	molybdate ion transport
kpn2146_RS08385	COG2005	Transcriptional regulator
kpn2146_RS08395	COG0725	ABC transporter, periplasmic molybdate-binding protein
kpn2146_RS08400	COG4149	molybdate abc transporter
kpn2146_RS08405	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
kpn2146_RS08410	COG0561	phosphatase activity
kpn2146_RS08435	COG2200	EAL domain
kpn2146_RS08440	COG0789	Transcriptional regulator
kpn2146_RS08475	COG4677	pectinesterase activity
kpn2146_RS08510	COG1881	PFAM PEBP family protein
kpn2146_RS08515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
kpn2146_RS08530	COG2226	methyltransferase
kpn2146_RS08555	COG0642	Histidine kinase
kpn2146_RS08560	COG0745	RESPONSE REGULATOR receiver
kpn2146_RS08580	COG0521	Mo-molybdopterin cofactor biosynthetic process
kpn2146_RS08590	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
kpn2146_RS08595	COG0314	molybdopterin synthase activity
kpn2146_RS08600	COG0670	Belongs to the BI1 family
kpn2146_RS08605	COG0392	lysyltransferase activity
kpn2146_RS08610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
kpn2146_RS08615	COG3568	Endonuclease Exonuclease Phosphatase
kpn2146_RS08625	COG0842	Transport permease protein
kpn2146_RS08630	COG0842	Transport permease protein
kpn2146_RS08635	COG1131	(ABC) transporter
kpn2146_RS08640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
kpn2146_RS08645	COG1309	transcriptional regulator
kpn2146_RS08650	COG0583	DNA-binding transcription factor activity
kpn2146_RS08660	COG2271	Major facilitator Superfamily
kpn2146_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS08670	COG3959	Transketolase, thiamine diphosphate binding domain
kpn2146_RS08675	COG3958	Transketolase
kpn2146_RS08680	COG0513	Belongs to the DEAD box helicase family
kpn2146_RS08685	COG1199	ATP-dependent helicase activity
kpn2146_RS08690	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
kpn2146_RS08700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
kpn2146_RS08710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
kpn2146_RS08720	COG0668	transmembrane transport
kpn2146_RS08725	COG1126	abc transporter atp-binding protein
kpn2146_RS08730	COG0765	amino acid transport
kpn2146_RS08735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
kpn2146_RS08755	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
kpn2146_RS08760	COG2194	sulfuric ester hydrolase activity
kpn2146_RS08770	COG1321	iron dependent repressor
kpn2146_RS08775	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
kpn2146_RS08780	COG2723	6-phospho-beta-galactosidase activity
kpn2146_RS08785	COG2188	Transcriptional regulator
kpn2146_RS08790	COG1376	ErfK ybiS ycfS ynhG family protein
kpn2146_RS08795	COG2365	Tyrosine phosphatase family
kpn2146_RS08800	COG0488	(ABC) transporter
kpn2146_RS08815	COG2271	Major facilitator Superfamily
kpn2146_RS08820	COG1609	Transcriptional regulator
kpn2146_RS08830	COG0561	phosphatase activity
kpn2146_RS08835	COG1882	Formate acetyltransferase
kpn2146_RS08840	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
kpn2146_RS08845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
kpn2146_RS08850	COG0303	'Molybdopterin
kpn2146_RS08865	COG0747	negative chemotaxis
kpn2146_RS08885	COG2223	nitrite transmembrane transporter activity
kpn2146_RS08895	COG2133	pyrroloquinoline quinone binding
kpn2146_RS08900	COG0625	glutathione transferase activity
kpn2146_RS08910	COG1686	Belongs to the peptidase S11 family
kpn2146_RS08915	COG1349	DNA-binding transcription factor activity
kpn2146_RS08920	COG0671	phosphoesterase, PA-phosphatase related
kpn2146_RS08925	COG2814	Major facilitator Superfamily
kpn2146_RS08930	COG0561	phosphatase activity
kpn2146_RS08935	COG0738	Major facilitator superfamily
kpn2146_RS08940	COG3226	Transcriptional regulator
kpn2146_RS08945	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
kpn2146_RS08950	COG3344	reverse transcriptase
kpn2146_RS08985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
kpn2146_RS09020	COG4695	Portal protein
kpn2146_RS09195	COG0778	Nitroreductase
kpn2146_RS09205	COG0778	Nitroreductase
kpn2146_RS09220	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
kpn2146_RS09225	COG3842	ATPase activity
kpn2146_RS09230	COG1176	ABC-type spermidine putrescine transport system, permease component I
kpn2146_RS09235	COG1177	transmembrane transport
kpn2146_RS09250	COG0745	RESPONSE REGULATOR receiver
kpn2146_RS09255	COG5002	protein histidine kinase activity
kpn2146_RS09260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
kpn2146_RS09265	COG4160	amino acid transport
kpn2146_RS09270	COG4215	(ABC) transporter
kpn2146_RS09275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
kpn2146_RS09280	COG1126	abc transporter atp-binding protein
kpn2146_RS09290	COG2203	Gaf domain
kpn2146_RS09290	COG3706	GGDEF domain
kpn2146_RS09290	COG5001	Diguanylate cyclase
kpn2146_RS09290	COG4251	negative regulation of phosphorylation
kpn2146_RS09295	COG3023	N-Acetylmuramoyl-L-alanine amidase
kpn2146_RS09300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
kpn2146_RS09305	COG0702	epimerase
kpn2146_RS09310	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
kpn2146_RS09315	COG0028	Belongs to the TPP enzyme family
kpn2146_RS09325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
kpn2146_RS09335	COG2431	L-lysine efflux transmembrane transporter activity
kpn2146_RS09345	COG3593	DNA synthesis involved in DNA repair
kpn2146_RS09350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
kpn2146_RS09360	COG1278	Cold shock
kpn2146_RS09370	COG0542	response to heat
kpn2146_RS09385	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
kpn2146_RS09390	COG4988	ABC transporter
kpn2146_RS09395	COG0492	ferredoxin-NADP+ reductase activity
kpn2146_RS09410	COG1674	ftsk spoiiie
kpn2146_RS09410	COG1178	ABC-type Fe3 transport system permease component
kpn2146_RS09420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
kpn2146_RS09430	COG0243	molybdopterin cofactor binding
kpn2146_RS09435	COG0437	4 iron, 4 sulfur cluster binding
kpn2146_RS09440	COG3302	dmso reductase anchor subunit
kpn2146_RS09450	COG0477	Major facilitator Superfamily
kpn2146_RS09455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
kpn2146_RS09460	COG1882	Formate acetyltransferase
kpn2146_RS09465	COG2116	formate transmembrane transporter activity
kpn2146_RS09470	COG1944	ATP diphosphatase activity
kpn2146_RS09475	COG2323	membrane
kpn2146_RS09495	COG0539	negative regulation of cytoplasmic translation
kpn2146_RS09505	COG0658	competence protein
kpn2146_RS09505	COG2333	competence protein COMEC
kpn2146_RS09520	COG3214	Protein conserved in bacteria
kpn2146_RS09535	COG3173	Aminoglycoside phosphotransferase
kpn2146_RS09540	COG1434	Gram-negative-bacterium-type cell wall biogenesis
kpn2146_RS09545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
kpn2146_RS09555	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
kpn2146_RS09565	COG2989	Protein conserved in bacteria
kpn2146_RS09570	COG3108	Peptidase M15
kpn2146_RS09575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
kpn2146_RS09580	COG1448	Aminotransferase
kpn2146_RS09595	COG1522	sequence-specific DNA binding
kpn2146_RS09605	COG0814	amino acid
kpn2146_RS09615	COG1473	amidohydrolase
kpn2146_RS09630	COG0308	aminopeptidase N
kpn2146_RS09640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
kpn2146_RS09645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
kpn2146_RS09650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
kpn2146_RS09655	COG0431	NADPH-dependent FMN reductase
kpn2146_RS09670	COG3217	Mosc domain protein beta barrel domain protein
kpn2146_RS09670	COG0633	Ferredoxin
kpn2146_RS09680	COG0488	(ABC) transporter
kpn2146_RS09685	COG2995	paraquat-inducible protein a
kpn2146_RS09690	COG3008	intermembrane lipid transfer
kpn2146_RS09690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
kpn2146_RS09695	COG3009	Protein conserved in bacteria
kpn2146_RS09700	COG3130	regulation of translation
kpn2146_RS09710	COG1067	ATP-dependent peptidase activity
kpn2146_RS09730	COG3070	regulator of competence-specific genes
kpn2146_RS09735	COG1289	transmembrane transporter activity
kpn2146_RS09740	COG3304	Inner membrane component domain
kpn2146_RS09745	COG0210	DNA helicase
kpn2146_RS09755	COG1832	CoA-binding protein
kpn2146_RS09770	COG1881	PFAM PEBP family protein
kpn2146_RS09775	COG2207	Transcriptional regulator
kpn2146_RS09790	COG0670	Belongs to the BI1 family
kpn2146_RS09845	COG2916	Histone family protein nucleoid-structuring protein H-NS
kpn2146_RS09925	COG0582	viral genome integration into host DNA
kpn2146_RS09930	COG2200	EAL domain
kpn2146_RS09935	COG2200	EAL domain
kpn2146_RS09945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
kpn2146_RS09950	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS09955	COG4638	Rieske (2fe-2S)
kpn2146_RS09960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
kpn2146_RS09965	COG0473	3-isopropylmalate dehydrogenase activity
kpn2146_RS09970	COG0583	DNA-binding transcription factor activity
kpn2146_RS09975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
kpn2146_RS09980	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS09985	COG1917	Cupin 2, conserved barrel domain protein
kpn2146_RS09985	COG1396	sequence-specific DNA binding
kpn2146_RS09990	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
kpn2146_RS09995	COG0174	glutamine synthetase
kpn2146_RS10000	COG0531	amino acid
kpn2146_RS10015	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS10045	COG3729	General stress protein
kpn2146_RS10055	COG2233	PERMEase
kpn2146_RS10090	COG1309	transcriptional regulator
kpn2146_RS10105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
kpn2146_RS10115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
kpn2146_RS10135	COG1702	phosphate starvation-inducible protein PhoH
kpn2146_RS10140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
kpn2146_RS10150	COG1335	isochorismatase
kpn2146_RS10160	COG0583	DNA-binding transcription factor activity
kpn2146_RS10195	COG3381	protein complex oligomerization
kpn2146_RS10230	COG5645	(Lipo)protein
kpn2146_RS10245	COG1560	Kdo2-lipid A biosynthetic process
kpn2146_RS10295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
kpn2146_RS10315	COG2814	Major facilitator Superfamily
kpn2146_RS10320	COG0583	DNA-binding transcription factor activity
kpn2146_RS10325	COG1530	ribonuclease E activity
kpn2146_RS10340	COG1399	metal-binding, possibly nucleic acid-binding protein
kpn2146_RS10360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
kpn2146_RS10375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
kpn2146_RS10380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
kpn2146_RS10385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
kpn2146_RS10395	COG0470	DNA polymerase III
kpn2146_RS10400	COG0084	hydrolase, TatD family'
kpn2146_RS10410	COG0537	adenosine 5'-monophosphoramidase activity
kpn2146_RS10415	COG5633	Lipoprotein
kpn2146_RS10440	COG1252	NADH dehydrogenase
kpn2146_RS10445	COG3134	Outer membrane lipoprotein
kpn2146_RS10460	COG1309	transcriptional regulator
kpn2146_RS10475	COG1376	ErfK ybiS ycfS ynhG family protein
kpn2146_RS10475	COG1388	LysM domain
kpn2146_RS10480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
kpn2146_RS10490	COG4591	ABC-type transport system involved in lipoprotein release permease component
kpn2146_RS10500	COG4591	ABC-type transport system involved in lipoprotein release permease component
kpn2146_RS10510	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
kpn2146_RS10520	COG0318	PFAM AMP-dependent synthetase and ligase
kpn2146_RS10535	COG1177	transmembrane transport
kpn2146_RS10555	COG2850	peptidyl-arginine hydroxylation
kpn2146_RS10560	COG2205	protein histidine kinase activity
kpn2146_RS10580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
kpn2146_RS10600	COG1187	pseudouridine synthase activity
kpn2146_RS10605	COG0538	isocitrate dehydrogenase activity
kpn2146_RS10610	COG0640	Transcriptional regulator
kpn2146_RS10630	COG3813	Protein conserved in bacteria
kpn2146_RS10635	COG1063	alcohol dehydrogenase
kpn2146_RS10645	COG3729	General stress protein
kpn2146_RS10650	COG3685	Protein conserved in bacteria
kpn2146_RS10655	COG3685	Protein conserved in bacteria
kpn2146_RS10660	COG3546	catalase activity
kpn2146_RS10665	COG1271	oxidase subunit
kpn2146_RS10670	COG1294	oxidase, subunit
kpn2146_RS10700	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
kpn2146_RS10705	COG0583	DNA-binding transcription factor activity
kpn2146_RS10710	COG3706	GGDEF domain
kpn2146_RS10715	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
kpn2146_RS10735	COG1560	Kdo2-lipid A biosynthetic process
kpn2146_RS10745	COG3182	Iron-regulated membrane protein
kpn2146_RS10760	COG2199	diguanylate cyclase activity
kpn2146_RS10760	COG2203	Gaf domain
kpn2146_RS10765	COG3042	response to heat
kpn2146_RS10770	COG3189	MarR family transcriptional regulator
kpn2146_RS10775	COG1683	Conserved Protein
kpn2146_RS10780	COG0504	CTP synthase activity
kpn2146_RS10785	COG2807	transmembrane transport
kpn2146_RS10790	COG2207	Transcriptional regulator
kpn2146_RS10800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
kpn2146_RS10805	COG0859	PFAM glycosyl transferase family 9
kpn2146_RS10815	COG3344	reverse transcriptase
kpn2146_RS10820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
kpn2146_RS10825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
kpn2146_RS10830	COG0583	DNA-binding transcription factor activity
kpn2146_RS10835	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS10860	COG0386	Belongs to the glutathione peroxidase family
kpn2146_RS10875	COG2766	serine protein kinase
kpn2146_RS10880	COG3713	MltA-interacting MipA family protein
kpn2146_RS10885	COG0656	L-ascorbic acid biosynthetic process
kpn2146_RS10905	COG3139	Protein of unknown function (DUF1315)
kpn2146_RS10920	COG1063	alcohol dehydrogenase
kpn2146_RS10925	COG2271	Major facilitator Superfamily
kpn2146_RS10930	COG1063	alcohol dehydrogenase
kpn2146_RS10935	COG0191	fructose-bisphosphate aldolase activity
kpn2146_RS10940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
kpn2146_RS10945	COG0667	Aldo Keto reductase
kpn2146_RS10950	COG1349	DNA-binding transcription factor activity
kpn2146_RS10955	COG2814	Major facilitator Superfamily
kpn2146_RS10960	COG1335	isochorismatase
kpn2146_RS10965	COG0252	asparaginase activity
kpn2146_RS10970	COG0616	signal peptide processing
kpn2146_RS10975	COG0778	Nitroreductase
kpn2146_RS10985	COG2801	Transposase and inactivated derivatives
kpn2146_RS10995	COG0709	Synthesizes selenophosphate from selenide and ATP
kpn2146_RS11000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
kpn2146_RS11005	COG0604	alcohol dehydrogenase
kpn2146_RS11005	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS11005	COG3321	synthase
kpn2146_RS11010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
kpn2146_RS11020	COG0494	nUDIX hydrolase
kpn2146_RS11025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
kpn2146_RS11030	COG2897	thiosulfate sulfurtransferase activity
kpn2146_RS11035	COG4136	ATPase activity
kpn2146_RS11040	COG4135	transport system, permease component
kpn2146_RS11045	COG4134	Bacterial extracellular solute-binding protein
kpn2146_RS11050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
kpn2146_RS11055	COG0398	Pfam SNARE associated Golgi protein
kpn2146_RS11060	COG0398	Pfam SNARE associated Golgi protein
kpn2146_RS11065	COG0708	Exodeoxyribonuclease III
kpn2146_RS11075	COG3138	arginine N-succinyltransferase
kpn2146_RS11085	COG3724	N-succinylarginine dihydrolase activity
kpn2146_RS11100	COG3678	ATP-independent chaperone mediated protein folding
kpn2146_RS11105	COG0322	excinuclease ABC activity
kpn2146_RS11115	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
kpn2146_RS11120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
kpn2146_RS11130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
kpn2146_RS11135	COG1447	Phosphotransferase system cellobiose-specific component IIA
kpn2146_RS11140	COG1917	Cupin 2, conserved barrel domain protein
kpn2146_RS11140	COG2169	Transcriptional regulator
kpn2146_RS11145	COG1486	melibiose metabolic process
kpn2146_RS11155	COG0753	catalase activity
kpn2146_RS11165	COG1823	symporter activity
kpn2146_RS11170	COG1988	membrane-bound metal-dependent
kpn2146_RS11175	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS11180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
kpn2146_RS11210	COG0727	PFAM Uncharacterised protein family (UPF0153)
kpn2146_RS11215	COG3047	cAMP biosynthetic process
kpn2146_RS11225	COG4774	siderophore transport
kpn2146_RS11280	COG0135	phosphoribosylanthranilate isomerase activity
kpn2146_RS11280	COG0134	indole-3-glycerol-phosphate synthase activity
kpn2146_RS11285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
kpn2146_RS11285	COG0512	Glutamine amidotransferase of anthranilate synthase
kpn2146_RS11290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
kpn2146_RS11300	COG0009	L-threonylcarbamoyladenylate synthase
kpn2146_RS11310	COG0583	DNA-binding transcription factor activity
kpn2146_RS11320	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
kpn2146_RS11325	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS11335	COG0616	signal peptide processing
kpn2146_RS11370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
kpn2146_RS11380	COG0671	phosphoesterase, PA-phosphatase related
kpn2146_RS11385	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
kpn2146_RS11390	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
kpn2146_RS11400	COG0023	Translation Initiation Factor
kpn2146_RS11415	COG1349	DNA-binding transcription factor activity
kpn2146_RS11430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
kpn2146_RS11430	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
kpn2146_RS11440	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
kpn2146_RS11450	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
kpn2146_RS11465	COG4171	peptide transport system, permease
kpn2146_RS11585	COG3344	reverse transcriptase
kpn2146_RS11590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
kpn2146_RS11595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
kpn2146_RS11600	COG2135	peptidase activity
kpn2146_RS11615	COG0702	epimerase
kpn2146_RS11630	COG1473	amidohydrolase
kpn2146_RS11640	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
kpn2146_RS11645	COG1842	Phage shock protein A
kpn2146_RS11655	COG1983	PspC domain protein
kpn2146_RS11665	COG3106	COG3106 Predicted ATPase
kpn2146_RS11675	COG0583	DNA-binding transcription factor activity
kpn2146_RS11680	COG1486	melibiose metabolic process
kpn2146_RS11690	COG3180	Ammonia monooxygenase
kpn2146_RS11695	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
kpn2146_RS11700	COG4948	Mandelate Racemase Muconate Lactonizing
kpn2146_RS11705	COG2866	Carboxypeptidase
kpn2146_RS11715	COG4166	transmembrane transport
kpn2146_RS11745	COG0656	L-ascorbic acid biosynthetic process
kpn2146_RS11760	COG0583	DNA-binding transcription factor activity
kpn2146_RS11765	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS11770	COG1078	dGTPase activity
kpn2146_RS11775	COG0693	protein deglycase activity
kpn2146_RS11780	COG0582	viral genome integration into host DNA
kpn2146_RS11885	COG0484	heat shock protein binding
kpn2146_RS11905	COG3772	lysozyme
kpn2146_RS11925	COG1783	phage Terminase large subunit
kpn2146_RS11930	COG3567	Phage-associated protein, HI1409 family
kpn2146_RS12000	COG0741	lytic transglycosylase activity
kpn2146_RS12000	COG0739	heme binding
kpn2146_RS12000	COG1196	nuclear chromosome segregation
kpn2146_RS12085	COG3344	reverse transcriptase
kpn2146_RS12125	COG2885	chlorophyll binding
kpn2146_RS12230	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS12235	COG1309	transcriptional regulator
kpn2146_RS12240	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS12260	COG0583	DNA-binding transcription factor activity
kpn2146_RS12285	COG0604	alcohol dehydrogenase
kpn2146_RS12290	COG0436	Aminotransferase
kpn2146_RS12305	COG2011	ABC-type metal ion transport system permease component
kpn2146_RS12310	COG1448	Aminotransferase
kpn2146_RS12320	COG1522	sequence-specific DNA binding
kpn2146_RS12325	COG1113	amino acid transport
kpn2146_RS12340	COG0673	inositol 2-dehydrogenase activity
kpn2146_RS12345	COG1349	DNA-binding transcription factor activity
kpn2146_RS12355	COG0513	Belongs to the DEAD box helicase family
kpn2146_RS12365	COG0589	response to stress
kpn2146_RS12375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
kpn2146_RS12380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
kpn2146_RS12380	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
kpn2146_RS12380	COG0674	pyruvate-flavodoxin oxidoreductase activity
kpn2146_RS12380	COG1013	pyruvate-flavodoxin oxidoreductase activity
kpn2146_RS12385	COG3042	response to heat
kpn2146_RS12390	COG3187	Heat shock protein
kpn2146_RS12395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
kpn2146_RS12400	COG0586	Pfam SNARE associated Golgi protein
kpn2146_RS12405	COG2911	Protein conserved in bacteria
kpn2146_RS12415	COG3784	Protein of unknown function (DUF1318)
kpn2146_RS12420	COG2207	Transcriptional regulator
kpn2146_RS12425	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS12445	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS12445	COG2030	dehydratase
kpn2146_RS12450	COG3396	Phenylacetate-CoA oxygenase
kpn2146_RS12455	COG3460	Phenylacetate-CoA oxygenase
kpn2146_RS12460	COG3396	Phenylacetate-CoA oxygenase
kpn2146_RS12465	COG2151	metal-sulfur cluster biosynthetic enzyme
kpn2146_RS12470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
kpn2146_RS12475	COG1024	Enoyl-CoA hydratase
kpn2146_RS12480	COG1024	Enoyl-CoA hydratase
kpn2146_RS12485	COG1250	3-hydroxyacyl-CoA dehydrogenase
kpn2146_RS12490	COG2050	protein possibly involved in aromatic compounds catabolism
kpn2146_RS12495	COG0183	Belongs to the thiolase family
kpn2146_RS12500	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
kpn2146_RS12505	COG3327	negative regulation of DNA-templated transcription, initiation
kpn2146_RS12510	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
kpn2146_RS12525	COG1643	Atp-dependent helicase
kpn2146_RS12530	COG4122	O-methyltransferase activity
kpn2146_RS12555	COG0583	DNA-binding transcription factor activity
kpn2146_RS12560	COG0667	Aldo Keto reductase
kpn2146_RS12565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
kpn2146_RS12575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
kpn2146_RS12580	COG3138	arginine N-succinyltransferase
kpn2146_RS12585	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS12590	COG3724	N-succinylarginine dihydrolase activity
kpn2146_RS12595	COG2988	succinylglutamate desuccinylase activity
kpn2146_RS12600	COG1113	amino acid transport
kpn2146_RS12605	COG0477	Major facilitator Superfamily
kpn2146_RS12610	COG1434	Gram-negative-bacterium-type cell wall biogenesis
kpn2146_RS12620	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS12625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
kpn2146_RS12630	COG0401	homolog of Blt101
kpn2146_RS12635	COG5562	phage envelope protein
kpn2146_RS12640	COG0425	Belongs to the sulfur carrier protein TusA family
kpn2146_RS12645	COG2391	methyltransferase activity
kpn2146_RS12670	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
kpn2146_RS12675	COG1263	PTS System
kpn2146_RS12675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
kpn2146_RS12680	COG1609	Transcriptional regulator
kpn2146_RS12685	COG5339	Protein conserved in bacteria
kpn2146_RS12690	COG1482	cell wall glycoprotein biosynthetic process
kpn2146_RS12695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
kpn2146_RS12695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
kpn2146_RS12700	COG0114	fumarate hydratase activity
kpn2146_RS12710	COG2205	protein histidine kinase activity
kpn2146_RS12720	COG0745	RESPONSE REGULATOR receiver
kpn2146_RS12725	COG3136	membrane protein required for alginate biosynthesis
kpn2146_RS12735	COG0531	amino acid
kpn2146_RS12760	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
kpn2146_RS12765	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
kpn2146_RS12780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
kpn2146_RS12795	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
kpn2146_RS12800	COG1473	amidohydrolase
kpn2146_RS12810	COG0583	DNA-binding transcription factor activity
kpn2146_RS12815	COG2840	Smr protein MutS2
kpn2146_RS12820	COG1414	Transcriptional regulator
kpn2146_RS12830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
kpn2146_RS12835	COG0183	Belongs to the thiolase family
kpn2146_RS12845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
kpn2146_RS12850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
kpn2146_RS12860	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
kpn2146_RS12860	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
kpn2146_RS12885	COG4565	transcriptional regulatory protein
kpn2146_RS12890	COG3290	protein histidine kinase activity
kpn2146_RS12915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
kpn2146_RS12925	COG0679	Auxin Efflux Carrier
kpn2146_RS12955	COG0628	permease
kpn2146_RS12975	COG3591	Belongs to the peptidase S1B family
kpn2146_RS12995	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
kpn2146_RS13000	COG2814	Major facilitator Superfamily
kpn2146_RS13005	COG0583	DNA-binding transcription factor activity
kpn2146_RS13010	COG1940	carbohydrate kinase activity
kpn2146_RS13015	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
kpn2146_RS13030	COG3302	dmso reductase anchor subunit
kpn2146_RS13035	COG0437	4 iron, 4 sulfur cluster binding
kpn2146_RS13040	COG0243	molybdopterin cofactor binding
kpn2146_RS13055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
kpn2146_RS13070	COG2271	Major facilitator Superfamily
kpn2146_RS13075	COG0246	Mannitol dehydrogenase
kpn2146_RS13080	COG0589	response to stress
kpn2146_RS13085	COG1802	Transcriptional regulator
kpn2146_RS13090	COG4221	oxidoreductase activity
kpn2146_RS13105	COG2207	Transcriptional regulator
kpn2146_RS13110	COG2135	peptidase activity
kpn2146_RS13125	COG2197	response regulator
kpn2146_RS13140	COG0071	Belongs to the small heat shock protein (HSP20) family
kpn2146_RS13145	COG1546	Belongs to the CinA family
kpn2146_RS13150	COG2200	EAL domain
kpn2146_RS13160	COG3708	Transcriptional regulator
kpn2146_RS13160	COG2207	Transcriptional regulator
kpn2146_RS13165	COG2610	gluconate transmembrane transporter activity
kpn2146_RS13170	COG3622	Belongs to the hyi family
kpn2146_RS13175	COG0235	Class ii aldolase
kpn2146_RS13180	COG3395	kinase activity
kpn2146_RS13185	COG2084	Dehydrogenase
kpn2146_RS13190	COG1349	DNA-binding transcription factor activity
kpn2146_RS13205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
kpn2146_RS13210	COG2223	nitrite transmembrane transporter activity
kpn2146_RS13245	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
kpn2146_RS13250	COG0683	leucine binding
kpn2146_RS13270	COG0410	ABC transporter
kpn2146_RS13280	COG2814	Major facilitator Superfamily
kpn2146_RS13285	COG0697	spore germination
kpn2146_RS13295	COG4977	sequence-specific DNA binding
kpn2146_RS13325	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS13330	COG2731	YhcH YjgK YiaL family protein
kpn2146_RS13345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
kpn2146_RS13355	COG3395	kinase activity
kpn2146_RS13360	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
kpn2146_RS13365	COG1349	DNA-binding transcription factor activity
kpn2146_RS13370	COG0039	L-malate dehydrogenase activity
kpn2146_RS13380	COG0583	DNA-binding transcription factor activity
kpn2146_RS13385	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS13400	COG2199	diguanylate cyclase activity
kpn2146_RS13465	COG0477	Major facilitator Superfamily
kpn2146_RS13475	COG2070	2-Nitropropane dioxygenase
kpn2146_RS13480	COG2011	ABC-type metal ion transport system permease component
kpn2146_RS13500	COG4628	conserved protein (DUF2132)
kpn2146_RS13515	COG2207	Transcriptional regulator
kpn2146_RS13545	COG2233	PERMEase
kpn2146_RS13550	COG3648	Uricase
kpn2146_RS13550	COG3195	allantoin biosynthetic process
kpn2146_RS13555	COG2351	hydroxyisourate hydrolase activity
kpn2146_RS13560	COG1396	sequence-specific DNA binding
kpn2146_RS13565	COG3550	peptidyl-serine autophosphorylation
kpn2146_RS13570	COG1649	PFAM Uncharacterised BCR, COG1649
kpn2146_RS13580	COG3188	usher protein
kpn2146_RS13615	COG5001	Diguanylate cyclase
kpn2146_RS13615	COG3300	MHYT domain
kpn2146_RS13620	COG2819	hydrolase of the alpha beta superfamily
kpn2146_RS13640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS13640	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS13645	COG2814	Major facilitator Superfamily
kpn2146_RS13660	COG1263	PTS System
kpn2146_RS13660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
kpn2146_RS13665	COG2186	Transcriptional regulator
kpn2146_RS13685	COG3835	regulator
kpn2146_RS13690	COG1929	Belongs to the glycerate kinase type-1 family
kpn2146_RS13735	COG0738	Major facilitator superfamily
kpn2146_RS13740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
kpn2146_RS13745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
kpn2146_RS13750	COG1349	DNA-binding transcription factor activity
kpn2146_RS13765	COG1349	DNA-binding transcription factor activity
kpn2146_RS13770	COG4977	sequence-specific DNA binding
kpn2146_RS13790	COG4977	sequence-specific DNA binding
kpn2146_RS13805	COG2801	Transposase and inactivated derivatives
kpn2146_RS13820	COG0667	Aldo Keto reductase
kpn2146_RS13830	COG0667	Aldo Keto reductase
kpn2146_RS13835	COG0667	Aldo Keto reductase
kpn2146_RS13845	COG0456	acetyltransferase
kpn2146_RS13845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
kpn2146_RS13880	COG1652	LysM domain
kpn2146_RS13915	COG1609	Transcriptional regulator
kpn2146_RS13925	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS13940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
kpn2146_RS13950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
kpn2146_RS13955	COG0583	DNA-binding transcription factor activity
kpn2146_RS13960	COG0583	DNA-binding transcription factor activity
kpn2146_RS13975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
kpn2146_RS13975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
kpn2146_RS13975	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
kpn2146_RS13980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
kpn2146_RS13990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
kpn2146_RS13995	COG3037	sugar-specific permease SgaT UlaA
kpn2146_RS14005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS14010	COG1609	Transcriptional regulator
kpn2146_RS14020	COG2223	nitrite transmembrane transporter activity
kpn2146_RS14050	COG0477	Major facilitator Superfamily
kpn2146_RS14055	COG4529	Protein conserved in bacteria
kpn2146_RS14060	COG1902	pentaerythritol trinitrate reductase activity
kpn2146_RS14070	COG0583	DNA-binding transcription factor activity
kpn2146_RS14075	COG2070	2-Nitropropane dioxygenase
kpn2146_RS14085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
kpn2146_RS14095	COG0765	amino acid transport
kpn2146_RS14165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
kpn2146_RS14200	COG1335	isochorismatase
kpn2146_RS14240	COG1953	Uracil, thiamine, allantoin
kpn2146_RS14245	COG0402	S-adenosylhomocysteine deaminase activity
kpn2146_RS14250	COG3706	GGDEF domain
kpn2146_RS14255	COG1609	Transcriptional regulator
kpn2146_RS14265	COG0673	inositol 2-dehydrogenase activity
kpn2146_RS14275	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
kpn2146_RS14280	COG1116	anion transmembrane transporter activity
kpn2146_RS14285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
kpn2146_RS14290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
kpn2146_RS14295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
kpn2146_RS14300	COG0076	glutamate decarboxylase activity
kpn2146_RS14315	COG2205	protein histidine kinase activity
kpn2146_RS14325	COG0596	Alpha beta hydrolase
kpn2146_RS14365	COG0519	Catalyzes the synthesis of GMP from XMP
kpn2146_RS14365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
kpn2146_RS14385	COG0583	DNA-binding transcription factor activity
kpn2146_RS14395	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
kpn2146_RS14400	COG1285	pathogenesis
kpn2146_RS14405	COG2814	Major facilitator Superfamily
kpn2146_RS14410	COG1447	Phosphotransferase system cellobiose-specific component IIA
kpn2146_RS14415	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
kpn2146_RS14440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
kpn2146_RS14445	COG0583	DNA-binding transcription factor activity
kpn2146_RS14450	COG0243	molybdopterin cofactor binding
kpn2146_RS14455	COG3781	membrane
kpn2146_RS14480	COG1764	response to oxidative stress
kpn2146_RS14490	COG3111	PFAM Bacterial OB fold (BOF) protein
kpn2146_RS14500	COG2323	membrane
kpn2146_RS14510	COG0366	Alpha amylase catalytic
kpn2146_RS14520	COG3685	Protein conserved in bacteria
kpn2146_RS14530	COG3729	General stress protein
kpn2146_RS14535	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS14580	COG0488	(ABC) transporter
kpn2146_RS14600	COG1064	alcohol dehydrogenase
kpn2146_RS14605	COG0747	negative chemotaxis
kpn2146_RS14615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
kpn2146_RS14625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
kpn2146_RS14635	COG2814	Major facilitator Superfamily
kpn2146_RS14645	COG2326	polyphosphate kinase activity
kpn2146_RS14655	COG2864	formate dehydrogenase
kpn2146_RS14660	COG0437	4 iron, 4 sulfur cluster binding
kpn2146_RS14665	COG0243	molybdopterin cofactor binding
kpn2146_RS14665	COG3383	formate dehydrogenase (NAD+) activity
kpn2146_RS14670	COG0243	molybdopterin cofactor binding
kpn2146_RS14670	COG3383	formate dehydrogenase (NAD+) activity
kpn2146_RS14690	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
kpn2146_RS14700	COG3485	protocatechuate 3,4-dioxygenase
kpn2146_RS14705	COG4829	muconolactone delta-isomerase
kpn2146_RS14710	COG4948	Mandelate Racemase Muconate Lactonizing
kpn2146_RS14715	COG1414	Transcriptional regulator
kpn2146_RS14735	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
kpn2146_RS14740	COG1140	nitrate reductase beta subunit
kpn2146_RS14745	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
kpn2146_RS14750	COG2181	nitrate reductase activity
kpn2146_RS14755	COG2162	N-hydroxyarylamine O-acetyltransferase activity
kpn2146_RS14760	COG1178	ABC-type Fe3 transport system permease component
kpn2146_RS14765	COG1840	ABC-type Fe3 transport system, periplasmic component
kpn2146_RS14770	COG3842	ATPase activity
kpn2146_RS14775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
kpn2146_RS14790	COG2211	Major facilitator Superfamily
kpn2146_RS14810	COG0625	glutathione transferase activity
kpn2146_RS14820	COG1126	abc transporter atp-binding protein
kpn2146_RS14825	COG0765	amino acid transport
kpn2146_RS14835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
kpn2146_RS14840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
kpn2146_RS14845	COG1473	amidohydrolase
kpn2146_RS14850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
kpn2146_RS14855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
kpn2146_RS14880	COG4772	TonB-dependent receptor
kpn2146_RS14885	COG1228	amidohydrolase
kpn2146_RS14890	COG3691	Protein conserved in bacteria
kpn2146_RS14905	COG2130	NADP-dependent
kpn2146_RS14915	COG1247	-acetyltransferase
kpn2146_RS14920	COG3238	Protein conserved in bacteria
kpn2146_RS14930	COG0747	negative chemotaxis
kpn2146_RS14940	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS14970	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS14975	COG1177	transmembrane transport
kpn2146_RS14980	COG1176	ABC-type spermidine putrescine transport system, permease component I
kpn2146_RS14985	COG3842	ATPase activity
kpn2146_RS14990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
kpn2146_RS14995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
kpn2146_RS15000	COG1271	oxidase subunit
kpn2146_RS15005	COG1294	oxidase, subunit
kpn2146_RS15025	COG0826	peptidase U32
kpn2146_RS15035	COG1396	sequence-specific DNA binding
kpn2146_RS15040	COG3135	benzoate transporter
kpn2146_RS15045	COG2207	Transcriptional regulator
kpn2146_RS15045	COG3708	Transcriptional regulator
kpn2146_RS15060	COG0500	methyltransferase
kpn2146_RS15065	COG1275	C4-dicarboxylate transporter malic acid transport protein
kpn2146_RS15070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
kpn2146_RS15075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
kpn2146_RS15090	COG2272	Belongs to the type-B carboxylesterase lipase family
kpn2146_RS15095	COG5383	Protein conserved in bacteria
kpn2146_RS15100	COG3485	protocatechuate 3,4-dioxygenase
kpn2146_RS15105	COG3485	protocatechuate 3,4-dioxygenase
kpn2146_RS15110	COG0583	DNA-binding transcription factor activity
kpn2146_RS15130	COG3038	cytochrome b561
kpn2146_RS15150	COG2814	Major facilitator Superfamily
kpn2146_RS15160	COG0673	inositol 2-dehydrogenase activity
kpn2146_RS15200	COG4659	FMN binding
kpn2146_RS15210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
kpn2146_RS15225	COG0625	glutathione transferase activity
kpn2146_RS15230	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
kpn2146_RS15245	COG3895	Periplasmic Protein
kpn2146_RS15260	COG3706	GGDEF domain
kpn2146_RS15275	COG1566	PFAM secretion protein HlyD family protein
kpn2146_RS15280	COG1289	transmembrane transporter activity
kpn2146_RS15285	COG2032	superoxide dismutase activity
kpn2146_RS15290	COG4989	oxidoreductase activity
kpn2146_RS15295	COG3313	Fe-S protein
kpn2146_RS15300	COG1309	transcriptional regulator
kpn2146_RS15305	COG1902	pentaerythritol trinitrate reductase activity
kpn2146_RS15310	COG0346	lactoylglutathione lyase activity
kpn2146_RS15320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
kpn2146_RS15325	COG0791	NLP P60 protein
kpn2146_RS15340	COG2814	Major facilitator Superfamily
kpn2146_RS15350	COG0583	DNA-binding transcription factor activity
kpn2146_RS15355	COG2814	Major facilitator Superfamily
kpn2146_RS15360	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
kpn2146_RS15365	COG0307	riboflavin synthase, alpha
kpn2146_RS15420	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
kpn2146_RS15460	COG1349	DNA-binding transcription factor activity
kpn2146_RS15465	COG0346	lactoylglutathione lyase activity
kpn2146_RS15490	COG0444	Belongs to the ABC transporter superfamily
kpn2146_RS15495	COG4608	Belongs to the ABC transporter superfamily
kpn2146_RS15525	COG0604	alcohol dehydrogenase
kpn2146_RS15525	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS15525	COG3321	synthase
kpn2146_RS15565	COG0402	S-adenosylhomocysteine deaminase activity
kpn2146_RS15590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
kpn2146_RS15595	COG0277	FAD linked oxidase domain protein
kpn2146_RS15615	COG0583	DNA-binding transcription factor activity
kpn2146_RS15625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
kpn2146_RS15635	COG1250	3-hydroxyacyl-CoA dehydrogenase
kpn2146_RS15640	COG2610	gluconate transmembrane transporter activity
kpn2146_RS15645	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS15680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
kpn2146_RS15695	COG0745	RESPONSE REGULATOR receiver
kpn2146_RS15700	COG5002	protein histidine kinase activity
kpn2146_RS15700	COG3850	Histidine kinase
kpn2146_RS15715	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
kpn2146_RS15735	COG4235	cytochrome complex assembly
kpn2146_RS15735	COG3088	subunit of a heme lyase
kpn2146_RS15740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
kpn2146_RS15745	COG1138	Cytochrome C-type biogenesis protein
kpn2146_RS15760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
kpn2146_RS15765	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
kpn2146_RS15770	COG4133	protoheme IX ABC transporter activity
kpn2146_RS15800	COG1175	transmembrane transport
kpn2146_RS15815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
kpn2146_RS15820	COG3383	formate dehydrogenase (NAD+) activity
kpn2146_RS15825	COG1473	amidohydrolase
kpn2146_RS15855	COG1126	abc transporter atp-binding protein
kpn2146_RS15860	COG0765	amino acid transport
kpn2146_RS15885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
kpn2146_RS15890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
kpn2146_RS15895	COG1120	ATPase activity
kpn2146_RS15900	COG4774	siderophore transport
kpn2146_RS15905	COG1116	anion transmembrane transporter activity
kpn2146_RS15910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
kpn2146_RS15930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
kpn2146_RS15935	COG0583	DNA-binding transcription factor activity
kpn2146_RS15955	COG2814	Major facilitator Superfamily
kpn2146_RS15990	COG1414	Transcriptional regulator
kpn2146_RS15995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
kpn2146_RS16000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
kpn2146_RS16005	COG1120	ATPase activity
kpn2146_RS16015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
kpn2146_RS16020	COG2271	Major facilitator Superfamily
kpn2146_RS16025	COG3185	4-Hydroxyphenylpyruvate dioxygenase
kpn2146_RS16025	COG1082	Xylose isomerase domain protein TIM barrel
kpn2146_RS16030	COG1309	transcriptional regulator
kpn2146_RS16060	COG1376	ErfK ybiS ycfS ynhG family protein
kpn2146_RS16075	COG0719	Fe-S assembly protein
kpn2146_RS16080	COG0396	ATPase activity
kpn2146_RS16085	COG0719	Fe-S assembly protein
kpn2146_RS16090	COG0316	Belongs to the HesB IscA family
kpn2146_RS16110	COG1309	transcriptional regulator
kpn2146_RS16115	COG1304	FMN binding
kpn2146_RS16140	COG0583	DNA-binding transcription factor activity
kpn2146_RS16150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
kpn2146_RS16155	COG1120	ATPase activity
kpn2146_RS16185	COG2261	transglycosylase associated protein
kpn2146_RS16190	COG2050	protein possibly involved in aromatic compounds catabolism
kpn2146_RS16195	COG0277	FAD linked oxidase domain protein
kpn2146_RS16195	COG0247	lactate metabolic process
kpn2146_RS16200	COG0628	permease
kpn2146_RS16210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
kpn2146_RS16210	COG0574	Belongs to the PEP-utilizing enzyme family
kpn2146_RS16225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
kpn2146_RS16230	COG4256	Hemin uptake protein
kpn2146_RS16240	COG0791	NLP P60 protein
kpn2146_RS16250	COG0386	Belongs to the glutathione peroxidase family
kpn2146_RS16270	COG0583	DNA-binding transcription factor activity
kpn2146_RS16290	COG0072	phenylalanine-tRNA ligase activity
kpn2146_RS16290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
kpn2146_RS16325	COG3137	Salt-induced outer membrane protein
kpn2146_RS16330	COG1105	Belongs to the carbohydrate kinase PfkB family
kpn2146_RS16340	COG3001	Fructosamine kinase
kpn2146_RS16350	COG2350	Protein conserved in bacteria
kpn2146_RS16360	COG2353	YceI-like domain
kpn2146_RS16385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
kpn2146_RS16395	COG0444	Belongs to the ABC transporter superfamily
kpn2146_RS16400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
kpn2146_RS16405	COG0601	transmembrane transport
kpn2146_RS16410	COG4166	transmembrane transport
kpn2146_RS16420	COG2095	MarC family integral membrane protein
kpn2146_RS16430	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS16430	COG1454	alcohol dehydrogenase
kpn2146_RS16435	COG1435	thymidine kinase activity
kpn2146_RS16445	COG2916	Histone family protein nucleoid-structuring protein H-NS
kpn2146_RS16450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
kpn2146_RS16455	COG0745	RESPONSE REGULATOR receiver
kpn2146_RS16460	COG1752	Esterase of the alpha-beta hydrolase superfamily
kpn2146_RS16470	COG0788	formyltetrahydrofolate deformylase activity
kpn2146_RS16505	COG1522	sequence-specific DNA binding
kpn2146_RS16515	COG2181	nitrate reductase activity
kpn2146_RS16520	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
kpn2146_RS16525	COG1140	nitrate reductase beta subunit
kpn2146_RS16530	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
kpn2146_RS16540	COG2223	nitrite transmembrane transporter activity
kpn2146_RS16545	COG3850	Histidine kinase
kpn2146_RS16550	COG2197	response regulator
kpn2146_RS16555	COG4932	domain protein
kpn2146_RS16560	COG0243	molybdopterin cofactor binding
kpn2146_RS16565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
kpn2146_RS16565	COG2146	nitrite reductase [NAD(P)H] activity
kpn2146_RS16570	COG1116	anion transmembrane transporter activity
kpn2146_RS16580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
kpn2146_RS16590	COG3707	response regulator
kpn2146_RS16595	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
kpn2146_RS16605	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
kpn2146_RS16610	COG4572	Cation transport regulator
kpn2146_RS16615	COG0387	Pfam Sodium calcium exchanger
kpn2146_RS16635	COG2890	protein-(glutamine-N5) methyltransferase activity
kpn2146_RS16665	COG0659	secondary active sulfate transmembrane transporter activity
kpn2146_RS16685	COG0012	GTP binding
kpn2146_RS16775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
kpn2146_RS16830	COG2885	chlorophyll binding
kpn2146_RS16855	COG3122	Protein conserved in bacteria
kpn2146_RS16870	COG0583	DNA-binding transcription factor activity
kpn2146_RS16900	COG0583	DNA-binding transcription factor activity
kpn2146_RS16935	COG1882	Formate acetyltransferase
kpn2146_RS16950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
kpn2146_RS16955	COG0583	DNA-binding transcription factor activity
kpn2146_RS16995	COG2308	Evidence 4 Homologs of previously reported genes of
kpn2146_RS17005	COG4774	siderophore transport
kpn2146_RS17015	COG1619	proteins homologs of microcin C7 resistance protein MccF
kpn2146_RS17040	COG2719	SpoVR family
kpn2146_RS17070	COG0179	Fumarylacetoacetate (FAA) hydrolase
kpn2146_RS17090	COG2894	cell division
kpn2146_RS17100	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
kpn2146_RS17110	COG3065	identical protein binding
kpn2146_RS17120	COG1199	ATP-dependent helicase activity
kpn2146_RS17125	COG0251	oxidation-reduction process
kpn2146_RS17145	COG1760	l-serine dehydratase
kpn2146_RS17155	COG2200	EAL domain
kpn2146_RS17160	COG1253	flavin adenine dinucleotide binding
kpn2146_RS17165	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS17165	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
kpn2146_RS17170	COG3715	PTS system
kpn2146_RS17175	COG3716	PTS system mannose fructose sorbose family IID component
kpn2146_RS17190	COG2226	methyltransferase
kpn2146_RS17195	COG0768	penicillin binding
kpn2146_RS17225	COG1414	Transcriptional regulator
kpn2146_RS17230	COG2814	Major facilitator Superfamily
kpn2146_RS17250	COG1956	GAF domain-containing protein
kpn2146_RS17255	COG2995	paraquat-inducible protein a
kpn2146_RS17260	COG3008	intermembrane lipid transfer
kpn2146_RS17285	COG2990	Protein conserved in bacteria
kpn2146_RS17300	COG1276	copper resistance
kpn2146_RS17305	COG2372	response to copper ion
kpn2146_RS17315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
kpn2146_RS17320	COG1770	oligopeptidase
kpn2146_RS17325	COG2979	Protein of unknown function (DUF533)
kpn2146_RS17330	COG3141	response to X-ray
kpn2146_RS17340	COG0800	Aldolase
kpn2146_RS17345	COG0129	dihydroxy-acid dehydratase activity
kpn2146_RS17350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
kpn2146_RS17360	COG1737	Transcriptional regulator
kpn2146_RS17370	COG1560	Kdo2-lipid A biosynthetic process
kpn2146_RS17375	COG0739	heme binding
kpn2146_RS17380	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
kpn2146_RS17390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
kpn2146_RS17415	COG0494	nUDIX hydrolase
kpn2146_RS17425	COG1335	isochorismatase
kpn2146_RS17430	COG1801	Protein of unknown function DUF72
kpn2146_RS17435	COG3788	relative of glutathione S-transferase, MAPEG superfamily
kpn2146_RS17455	COG3102	Protein conserved in bacteria
kpn2146_RS17465	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
kpn2146_RS17490	COG1172	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS17500	COG1879	ABC-type sugar transport system periplasmic component
kpn2146_RS17505	COG1528	Iron-storage protein
kpn2146_RS17515	COG2211	Major facilitator Superfamily
kpn2146_RS17525	COG0477	Major facilitator Superfamily
kpn2146_RS17540	COG1528	Iron-storage protein
kpn2146_RS17550	COG0814	amino acid
kpn2146_RS17555	COG3012	SEC-C Motif Domain Protein
kpn2146_RS17555	COG3318	Belongs to the UPF0149 family
kpn2146_RS17590	COG2197	response regulator
kpn2146_RS17600	COG2197	response regulator
kpn2146_RS17605	COG1126	abc transporter atp-binding protein
kpn2146_RS17610	COG0765	amino acid transport
kpn2146_RS17620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
kpn2146_RS17625	COG0366	Alpha amylase catalytic
kpn2146_RS17655	COG2354	Protein conserved in bacteria
kpn2146_RS17660	COG0697	spore germination
kpn2146_RS17665	COG3727	T/G mismatch-specific endonuclease activity
kpn2146_RS17670	COG0270	DNA (cytosine-5-)-methyltransferase activity
kpn2146_RS17675	COG1418	mRNA catabolic process
kpn2146_RS17685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
kpn2146_RS17735	COG0025	NhaP-type Na H and K H
kpn2146_RS17740	COG1309	transcriptional regulator
kpn2146_RS17745	COG0604	alcohol dehydrogenase
kpn2146_RS17765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
kpn2146_RS17775	COG0534	Mate efflux family protein
kpn2146_RS17795	COG3706	GGDEF domain
kpn2146_RS17820	COG3615	Tellurite resistance protein tehB
kpn2146_RS17830	COG5001	Diguanylate cyclase
kpn2146_RS17830	COG3300	MHYT domain
kpn2146_RS17840	COG0477	Major facilitator Superfamily
kpn2146_RS17845	COG0095	Lipoate-protein ligase
kpn2146_RS17850	COG0583	DNA-binding transcription factor activity
kpn2146_RS17855	COG1942	4-Oxalocrotonate Tautomerase
kpn2146_RS17865	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
kpn2146_RS17885	COG1289	transmembrane transporter activity
kpn2146_RS17900	COG2925	Exonuclease
kpn2146_RS17905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
kpn2146_RS17910	COG0640	Transcriptional regulator
kpn2146_RS17915	COG0531	amino acid
kpn2146_RS17920	COG0583	DNA-binding transcription factor activity
kpn2146_RS17925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
kpn2146_RS17950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
kpn2146_RS17980	COG3677	Transposase
kpn2146_RS17980	COG1662	PFAM IS1 transposase
kpn2146_RS17985	COG0463	Glycosyl transferase, family 2
kpn2146_RS17990	COG2246	polysaccharide biosynthetic process
kpn2146_RS18000	COG0438	transferase activity, transferring glycosyl groups
kpn2146_RS18040	COG1215	transferase activity, transferring glycosyl groups
kpn2146_RS18050	COG2244	polysaccharide biosynthetic process
kpn2146_RS18115	COG2963	transposase activity
kpn2146_RS18120	COG2801	Transposase and inactivated derivatives
kpn2146_RS18125	COG3436	PFAM IS66 Orf2 family protein
kpn2146_RS18135	COG4372	Transposase
kpn2146_RS18140	COG3436	PFAM IS66 Orf2 family protein
kpn2146_RS18190	COG4372	Transposase
kpn2146_RS18195	COG3436	PFAM IS66 Orf2 family protein
kpn2146_RS18215	COG1253	flavin adenine dinucleotide binding
kpn2146_RS18220	COG2982	Protein involved in outer membrane biogenesis
kpn2146_RS18235	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
kpn2146_RS18240	COG0443	Heat shock 70 kDa protein
kpn2146_RS18270	COG1301	dicarboxylic acid transport
kpn2146_RS18280	COG1522	sequence-specific DNA binding
kpn2146_RS18290	COG4215	(ABC) transporter
kpn2146_RS18295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
kpn2146_RS18325	COG2205	protein histidine kinase activity
kpn2146_RS18330	COG0745	RESPONSE REGULATOR receiver
kpn2146_RS18350	COG0826	peptidase U32
kpn2146_RS18360	COG4608	Belongs to the ABC transporter superfamily
kpn2146_RS18365	COG0444	Belongs to the ABC transporter superfamily
kpn2146_RS18370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
kpn2146_RS18375	COG0601	transmembrane transport
kpn2146_RS18380	COG0747	negative chemotaxis
kpn2146_RS18390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
kpn2146_RS18400	COG1070	Carbohydrate kinase
kpn2146_RS18435	COG1830	Aldolase
kpn2146_RS18440	COG0351	phosphomethylpyrimidine kinase
kpn2146_RS18460	COG0583	DNA-binding transcription factor activity
kpn2146_RS18470	COG2252	PERMEase
kpn2146_RS18475	COG0583	DNA-binding transcription factor activity
kpn2146_RS18480	COG5455	response to cobalt ion
kpn2146_RS18500	COG4807	Protein conserved in bacteria
kpn2146_RS18510	COG3275	phosphorelay sensor kinase activity
kpn2146_RS18520	COG1174	glycine betaine transport
kpn2146_RS18525	COG1125	glycine betaine transport
kpn2146_RS18530	COG1174	glycine betaine transport
kpn2146_RS18535	COG1732	Glycine betaine
kpn2146_RS18540	COG1472	Belongs to the glycosyl hydrolase 3 family
kpn2146_RS18545	COG0277	FAD linked oxidase domain protein
kpn2146_RS18555	COG1686	Belongs to the peptidase S11 family
kpn2146_RS18565	COG0586	Pfam SNARE associated Golgi protein
kpn2146_RS18570	COG1538	Outer membrane efflux protein
kpn2146_RS18580	COG2723	6-phospho-beta-galactosidase activity
kpn2146_RS18595	COG3659	wide pore channel activity
kpn2146_RS18600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
kpn2146_RS18610	COG1346	cytolysis
kpn2146_RS18620	COG2949	membrane
kpn2146_RS18630	COG1129	ABC transporter
kpn2146_RS18645	COG2311	Membrane
kpn2146_RS18660	COG4771	TonB-dependent receptor
kpn2146_RS18665	COG2801	Transposase and inactivated derivatives
kpn2146_RS18675	COG0833	amino acid
kpn2146_RS18680	COG0583	DNA-binding transcription factor activity
kpn2146_RS18690	COG2855	membrane
kpn2146_RS18700	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
kpn2146_RS18700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
kpn2146_RS18700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
kpn2146_RS18705	COG1105	Belongs to the carbohydrate kinase PfkB family
kpn2146_RS18710	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS18710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS18730	COG1312	Catalyzes the dehydration of D-mannonate
kpn2146_RS18735	COG0246	Mannitol dehydrogenase
kpn2146_RS18740	COG0523	cobalamin synthesis protein
kpn2146_RS18745	COG0671	phosphoesterase, PA-phosphatase related
kpn2146_RS18750	COG0791	NLP P60 protein
kpn2146_RS18755	COG2200	EAL domain
kpn2146_RS18760	COG4166	transmembrane transport
kpn2146_RS18765	COG4174	ABC transporter (Permease)
kpn2146_RS18770	COG4239	(ABC) transporter, permease
kpn2146_RS18775	COG4172	Belongs to the ABC transporter superfamily
kpn2146_RS18785	COG2814	Major facilitator Superfamily
kpn2146_RS18790	COG1187	pseudouridine synthase activity
kpn2146_RS18795	COG1061	Type III restriction enzyme res subunit
kpn2146_RS18815	COG0494	nUDIX hydrolase
kpn2146_RS18820	COG1349	DNA-binding transcription factor activity
kpn2146_RS18845	COG0628	permease
kpn2146_RS18860	COG0659	secondary active sulfate transmembrane transporter activity
kpn2146_RS18865	COG2239	Acts as a magnesium transporter
kpn2146_RS18870	COG4615	Cyclic peptide transporter
kpn2146_RS18875	COG3145	DNA-N1-methyladenine dioxygenase activity
kpn2146_RS18880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
kpn2146_RS18880	COG2169	Transcriptional regulator
kpn2146_RS18900	COG2198	Histidine kinase
kpn2146_RS18900	COG0642	Histidine kinase
kpn2146_RS18910	COG2205	protein histidine kinase activity
kpn2146_RS18910	COG0784	Response regulator, receiver
kpn2146_RS18935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
kpn2146_RS18940	COG0584	glycerophosphoryl diester phosphodiesterase
kpn2146_RS18945	COG2271	Major facilitator Superfamily
kpn2146_RS18950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
kpn2146_RS18960	COG0247	lactate metabolic process
kpn2146_RS18970	COG2271	Major facilitator Superfamily
kpn2146_RS18980	COG1414	Transcriptional regulator
kpn2146_RS19000	COG5464	transposase or invertase
kpn2146_RS19010	COG0318	PFAM AMP-dependent synthetase and ligase
kpn2146_RS19035	COG1169	isochorismate synthase
kpn2146_RS19040	COG2153	protein acetylation
kpn2146_RS19055	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
kpn2146_RS19060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
kpn2146_RS19070	COG0839	Belongs to the complex I subunit 6 family
kpn2146_RS19120	COG0583	DNA-binding transcription factor activity
kpn2146_RS19125	COG0436	Aminotransferase
kpn2146_RS19135	COG0471	metal ion transport
kpn2146_RS19135	COG0490	domain, Protein
kpn2146_RS19140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
kpn2146_RS19160	COG0857	belongs to the CobB CobQ family
kpn2146_RS19160	COG0280	phosphate acetyltransferase
kpn2146_RS19165	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
kpn2146_RS19170	COG0622	Phosphoesterase
kpn2146_RS19175	COG0625	glutathione transferase activity
kpn2146_RS19180	COG0625	glutathione transferase activity
kpn2146_RS19185	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
kpn2146_RS19190	COG1090	epimerase
kpn2146_RS19205	COG4598	ABC transporter
kpn2146_RS19210	COG4160	amino acid transport
kpn2146_RS19235	COG0163	prenyltransferase activity
kpn2146_RS19240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
kpn2146_RS19245	COG1286	toxin biosynthetic process
kpn2146_RS19250	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
kpn2146_RS19255	COG0285	dihydrofolate synthase activity
kpn2146_RS19265	COG0586	Pfam SNARE associated Golgi protein
kpn2146_RS19275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
kpn2146_RS19295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
kpn2146_RS19310	COG3101	peptidyl-lysine hydroxylation
kpn2146_RS19315	COG0730	response to heat
kpn2146_RS19340	COG2062	phosphohistidine phosphatase, SixA
kpn2146_RS19355	COG3691	Protein conserved in bacteria
kpn2146_RS19365	COG2853	Lipoprotein
kpn2146_RS19370	COG2116	formate transmembrane transporter activity
kpn2146_RS19390	COG0583	DNA-binding transcription factor activity
kpn2146_RS19395	COG0590	tRNA wobble adenosine to inosine editing
kpn2146_RS19400	COG2807	transmembrane transport
kpn2146_RS19405	COG0436	Aminotransferase
kpn2146_RS19420	COG3275	phosphorelay sensor kinase activity
kpn2146_RS19425	COG3279	Response regulator of the LytR AlgR family
kpn2146_RS19440	COG3961	Belongs to the TPP enzyme family
kpn2146_RS19445	COG0667	Aldo Keto reductase
kpn2146_RS19460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
kpn2146_RS19465	COG2200	EAL domain
kpn2146_RS19465	COG2199	diguanylate cyclase activity
kpn2146_RS19480	COG3415	Transposase
kpn2146_RS19485	COG3415	Transposase
kpn2146_RS19510	COG0583	DNA-binding transcription factor activity
kpn2146_RS19515	COG0385	Bile acid
kpn2146_RS19520	COG3530	Putative quorum-sensing-regulated virulence factor
kpn2146_RS19545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
kpn2146_RS19585	COG4319	ketosteroid isomerase
kpn2146_RS19595	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
kpn2146_RS19600	COG4208	sulfate ABC transporter
kpn2146_RS19605	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
kpn2146_RS19610	COG4150	thiosulfate binding
kpn2146_RS19625	COG2837	iron assimilation
kpn2146_RS19645	COG0860	N-Acetylmuramoyl-L-alanine amidase
kpn2146_RS19735	COG4810	utilization protein
kpn2146_RS19745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
kpn2146_RS19750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
kpn2146_RS19755	COG5342	invasion associated locus B
kpn2146_RS19765	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
kpn2146_RS19765	COG0493	'glutamate synthase
kpn2146_RS19770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
kpn2146_RS19775	COG1393	Belongs to the ArsC family
kpn2146_RS19790	COG0400	carboxylic ester hydrolase activity
kpn2146_RS19795	COG1444	tRNA N-acetyltransferase activity
kpn2146_RS19800	COG2321	neutral zinc metallopeptidase
kpn2146_RS19810	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
kpn2146_RS19820	COG2716	regulation of RNA biosynthetic process
kpn2146_RS19825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
kpn2146_RS19830	COG0628	permease
kpn2146_RS19840	COG4783	chaperone-mediated protein folding
kpn2146_RS19845	COG1393	Belongs to the ArsC family
kpn2146_RS19860	COG2233	PERMEase
kpn2146_RS19870	COG2723	6-phospho-beta-galactosidase activity
kpn2146_RS19885	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
kpn2146_RS19900	COG2200	EAL domain
kpn2146_RS19920	COG0641	radical SAM
kpn2146_RS19925	COG3119	arylsulfatase activity
kpn2146_RS19935	COG3179	chitinase
kpn2146_RS20065	COG3344	reverse transcriptase
kpn2146_RS20120	COG3756	Protein conserved in bacteria
kpn2146_RS20150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
kpn2146_RS20190	COG0517	IMP dehydrogenase activity
kpn2146_RS20190	COG0516	GMP reductase activity
kpn2146_RS20200	COG1645	bacterial-type flagellum-dependent swarming motility
kpn2146_RS20220	COG2976	Protein conserved in bacteria
kpn2146_RS20250	COG4953	penicillin-binding protein 1C
kpn2146_RS20255	COG2373	Large extracellular alpha-helical protein
kpn2146_RS20260	COG2897	thiosulfate sulfurtransferase activity
kpn2146_RS20280	COG2975	iron-sulfur cluster assembly
kpn2146_RS20285	COG0633	Ferredoxin
kpn2146_RS20305	COG0822	iron-sulfur transferase activity
kpn2146_RS20335	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
kpn2146_RS20340	COG3683	transport system, periplasmic component
kpn2146_RS20345	COG3711	transcriptional antiterminator
kpn2146_RS20350	COG2814	Major facilitator Superfamily
kpn2146_RS20355	COG2017	converts alpha-aldose to the beta-anomer
kpn2146_RS20360	COG0477	Major facilitator Superfamily
kpn2146_RS20360	COG2814	Major facilitator Superfamily
kpn2146_RS20365	COG0457	Tetratricopeptide repeat
kpn2146_RS20370	COG1940	carbohydrate kinase activity
kpn2146_RS20375	COG2259	Doxx family
kpn2146_RS20385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
kpn2146_RS20385	COG1017	nitric oxide dioxygenase activity
kpn2146_RS20390	COG0347	Belongs to the P(II) protein family
kpn2146_RS20395	COG2204	response regulator
kpn2146_RS20400	COG3170	Tfp pilus assembly protein FimV
kpn2146_RS20405	COG2205	protein histidine kinase activity
kpn2146_RS20410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
kpn2146_RS20410	COG0047	phosphoribosylformylglycinamidine synthase activity
kpn2146_RS20425	COG0560	Phosphoserine phosphatase
kpn2146_RS20430	COG1737	Transcriptional regulator
kpn2146_RS20435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
kpn2146_RS20445	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
kpn2146_RS20470	COG0681	Belongs to the peptidase S26 family
kpn2146_RS20480	COG3086	response to oxidative stress
kpn2146_RS20485	COG3026	antisigma factor binding
kpn2146_RS20490	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
kpn2146_RS20500	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
kpn2146_RS20510	COG0513	Belongs to the DEAD box helicase family
kpn2146_RS20525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
kpn2146_RS20530	COG3118	belongs to the thioredoxin family
kpn2146_RS20535	COG3148	PFAM DTW domain containing protein
kpn2146_RS20545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
kpn2146_RS20550	COG5544	Lipoprotein
kpn2146_RS20555	COG0477	Major facilitator Superfamily
kpn2146_RS20585	COG0542	response to heat
kpn2146_RS20600	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
kpn2146_RS20605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
kpn2146_RS20610	COG0077	Prephenate dehydratase
kpn2146_RS20610	COG1605	Chorismate mutase
kpn2146_RS20620	COG1605	Chorismate mutase
kpn2146_RS20620	COG0287	Prephenate dehydrogenase
kpn2146_RS20625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
kpn2146_RS20635	COG2199	diguanylate cyclase activity
kpn2146_RS20640	COG2885	chlorophyll binding
kpn2146_RS20680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
kpn2146_RS20685	COG4137	Cytochrome C assembly protein
kpn2146_RS20690	COG4536	flavin adenine dinucleotide binding
kpn2146_RS20705	COG0497	DNA recombination
kpn2146_RS20725	COG2867	negative regulation of translational initiation
kpn2146_RS20875	COG4695	Portal protein
kpn2146_RS20915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
kpn2146_RS20945	COG4974	Belongs to the 'phage' integrase family
kpn2146_RS20970	COG3708	Transcriptional regulator
kpn2146_RS20970	COG2207	Transcriptional regulator
kpn2146_RS20975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
kpn2146_RS21010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
kpn2146_RS21020	COG0235	Class ii aldolase
kpn2146_RS21030	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS21045	COG2197	response regulator
kpn2146_RS21050	COG3539	Fimbrial protein
kpn2146_RS21060	COG3188	usher protein
kpn2146_RS21080	COG3121	Chaperone
kpn2146_RS21085	COG3539	Fimbrial protein
kpn2146_RS21095	COG3284	Transcriptional regulator
kpn2146_RS21100	COG0583	DNA-binding transcription factor activity
kpn2146_RS21110	COG0640	Transcriptional regulator
kpn2146_RS21115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
kpn2146_RS21130	COG2916	Histone family protein nucleoid-structuring protein H-NS
kpn2146_RS21150	COG4575	ribosome binding
kpn2146_RS21155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
kpn2146_RS21160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
kpn2146_RS21165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
kpn2146_RS21175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
kpn2146_RS21190	COG4176	ABC-type proline glycine betaine transport system permease component
kpn2146_RS21200	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
kpn2146_RS21215	COG1846	Transcriptional regulator
kpn2146_RS21225	COG1566	PFAM secretion protein HlyD family protein
kpn2146_RS21230	COG2814	Major facilitator Superfamily
kpn2146_RS21235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
kpn2146_RS21255	COG1238	metal cluster binding
kpn2146_RS21260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
kpn2146_RS21265	COG2823	Periplasmic or secreted lipoprotein
kpn2146_RS21300	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
kpn2146_RS21320	COG1546	Belongs to the CinA family
kpn2146_RS21325	COG0803	Belongs to the bacterial solute-binding protein 9 family
kpn2146_RS21330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
kpn2146_RS21335	COG1121	(ABC) transporter
kpn2146_RS21340	COG2951	lytic endotransglycosylase activity
kpn2146_RS21345	COG3730	PTS system glucitol sorbitol-specific
kpn2146_RS21350	COG3732	PTS system glucitol sorbitol-specific
kpn2146_RS21360	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS21365	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS21370	COG1349	DNA-binding transcription factor activity
kpn2146_RS21400	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
kpn2146_RS21405	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
kpn2146_RS21410	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
kpn2146_RS21415	COG1609	Transcriptional regulator
kpn2146_RS21425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
kpn2146_RS21425	COG1263	PTS System
kpn2146_RS21430	COG2723	6-phospho-beta-galactosidase activity
kpn2146_RS21440	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
kpn2146_RS21450	COG3260	NADH ubiquinone oxidoreductase 20
kpn2146_RS21455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
kpn2146_RS21460	COG3261	NADH dehydrogenase
kpn2146_RS21460	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
kpn2146_RS21465	COG0650	Formate hydrogenlyase subunit 4
kpn2146_RS21470	COG0651	ATP synthesis coupled electron transport
kpn2146_RS21475	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
kpn2146_RS21490	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
kpn2146_RS21495	COG0298	carbon dioxide binding
kpn2146_RS21500	COG0409	Hydrogenase expression formation protein
kpn2146_RS21505	COG0309	Hydrogenase expression formation protein (HypE)
kpn2146_RS21515	COG2723	6-phospho-beta-galactosidase activity
kpn2146_RS21525	COG4580	involved in the transport of maltose and maltodextrins
kpn2146_RS21535	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
kpn2146_RS21540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
kpn2146_RS21545	COG1447	Phosphotransferase system cellobiose-specific component IIA
kpn2146_RS21550	COG1940	carbohydrate kinase activity
kpn2146_RS21555	COG1609	Transcriptional regulator
kpn2146_RS21560	COG0803	Belongs to the bacterial solute-binding protein 9 family
kpn2146_RS21565	COG1121	(ABC) transporter
kpn2146_RS21570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
kpn2146_RS21575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
kpn2146_RS21590	COG0679	Auxin Efflux Carrier
kpn2146_RS21610	COG3720	iron ion transport
kpn2146_RS21615	COG4558	Periplasmic binding protein
kpn2146_RS21620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
kpn2146_RS21655	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
kpn2146_RS21660	COG0163	prenyltransferase activity
kpn2146_RS21685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
kpn2146_RS21690	COG1388	LysM domain
kpn2146_RS21690	COG4942	peptidase
kpn2146_RS21750	COG2234	aminopeptidase activity
kpn2146_RS21775	COG0720	synthase
kpn2146_RS21780	COG0602	queuosine metabolic process
kpn2146_RS21805	COG3956	TIGRFAM MazG family protein
kpn2146_RS21810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
kpn2146_RS21820	COG4999	Histidine kinase
kpn2146_RS21820	COG3437	response regulator, receiver
kpn2146_RS21820	COG3850	Histidine kinase
kpn2146_RS21820	COG2205	protein histidine kinase activity
kpn2146_RS21825	COG1929	Belongs to the glycerate kinase type-1 family
kpn2146_RS21830	COG4948	Mandelate Racemase Muconate Lactonizing
kpn2146_RS21835	COG4948	Mandelate Racemase Muconate Lactonizing
kpn2146_RS21840	COG2271	Major facilitator Superfamily
kpn2146_RS21845	COG0716	FMN binding
kpn2146_RS21850	COG0564	pseudouridine synthase activity
kpn2146_RS21855	COG3098	single-species biofilm formation
kpn2146_RS21870	COG1611	Belongs to the LOG family
kpn2146_RS21875	COG0814	amino acid
kpn2146_RS21880	COG1760	l-serine dehydratase
kpn2146_RS21885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
kpn2146_RS21895	COG0477	Major facilitator Superfamily
kpn2146_RS21900	COG1464	Belongs to the NlpA lipoprotein family
kpn2146_RS21905	COG2011	ABC-type metal ion transport system permease component
kpn2146_RS21910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
kpn2146_RS21925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
kpn2146_RS21945	COG1454	alcohol dehydrogenase
kpn2146_RS21950	COG0235	Class ii aldolase
kpn2146_RS21960	COG0738	Major facilitator superfamily
kpn2146_RS21980	COG1349	DNA-binding transcription factor activity
kpn2146_RS21990	COG2363	Small membrane protein
kpn2146_RS21995	COG0583	DNA-binding transcription factor activity
kpn2146_RS22005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
kpn2146_RS22010	COG2166	iron-sulfur cluster assembly
kpn2146_RS22015	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
kpn2146_RS22020	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
kpn2146_RS22185	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
kpn2146_RS22215	COG1454	alcohol dehydrogenase
kpn2146_RS22215	COG1012	belongs to the aldehyde dehydrogenase family
kpn2146_RS22220	COG4656	Part of a membrane complex involved in electron transport
kpn2146_RS22250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
kpn2146_RS22255	COG0860	N-Acetylmuramoyl-L-alanine amidase
kpn2146_RS22260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
kpn2146_RS22260	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
kpn2146_RS22270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
kpn2146_RS22275	COG1074	ATP-dependent DNA helicase activity
kpn2146_RS22280	COG1025	Belongs to the peptidase M16 family
kpn2146_RS22285	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
kpn2146_RS22290	COG4967	type IV pilus modification protein PilV
kpn2146_RS22300	COG4795	General secretion pathway protein
kpn2146_RS22305	COG2165	general secretion pathway protein
kpn2146_RS22340	COG0861	Integral membrane protein TerC family
kpn2146_RS22350	COG0667	Aldo Keto reductase
kpn2146_RS22370	COG1609	Transcriptional regulator
kpn2146_RS22380	COG2186	Transcriptional regulator
kpn2146_RS22385	COG2723	6-phospho-beta-galactosidase activity
kpn2146_RS22390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
kpn2146_RS22395	COG1609	Transcriptional regulator
kpn2146_RS22405	COG0583	DNA-binding transcription factor activity
kpn2146_RS22410	COG1794	racemase activity, acting on amino acids and derivatives
kpn2146_RS22415	COG1917	Cupin 2, conserved barrel domain protein
kpn2146_RS22420	COG1175	transmembrane transport
kpn2146_RS22425	COG0395	ABC-type sugar transport system, permease component
kpn2146_RS22430	COG3842	ATPase activity
kpn2146_RS22465	COG2814	Major facilitator Superfamily
kpn2146_RS22470	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS22480	COG0823	Involved in the tonB-independent uptake of proteins
kpn2146_RS22490	COG0183	Belongs to the thiolase family
kpn2146_RS22505	COG0814	amino acid
kpn2146_RS22510	COG0667	Aldo Keto reductase
kpn2146_RS22560	COG0697	spore germination
kpn2146_RS22565	COG1846	Transcriptional regulator
kpn2146_RS22570	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
kpn2146_RS22580	COG0582	viral genome integration into host DNA
kpn2146_RS22585	COG4974	Belongs to the 'phage' integrase family
kpn2146_RS22600	COG3539	Fimbrial protein
kpn2146_RS22605	COG3121	Chaperone
kpn2146_RS22610	COG3188	usher protein
kpn2146_RS22615	COG3539	Fimbrial protein
kpn2146_RS22620	COG3539	Fimbrial protein
kpn2146_RS22625	COG3539	Fimbrial protein
kpn2146_RS22635	COG2388	GCN5-related N-acetyl-transferase
kpn2146_RS22640	COG3592	Divergent 4Fe-4S mono-cluster
kpn2146_RS22655	COG1289	transmembrane transporter activity
kpn2146_RS22660	COG1538	Outer membrane efflux protein
kpn2146_RS22675	COG1393	Belongs to the ArsC family
kpn2146_RS22680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
kpn2146_RS22715	COG0667	Aldo Keto reductase
kpn2146_RS22730	COG2814	Major facilitator Superfamily
kpn2146_RS22740	COG4942	peptidase
kpn2146_RS22765	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
kpn2146_RS22775	COG4974	Belongs to the 'phage' integrase family
kpn2146_RS22780	COG0716	FMN binding
kpn2146_RS22790	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
kpn2146_RS22800	COG1272	protein, Hemolysin III
kpn2146_RS22810	COG1737	Transcriptional regulator
kpn2146_RS22815	COG2723	6-phospho-beta-galactosidase activity
kpn2146_RS22835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
kpn2146_RS22840	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS22860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
kpn2146_RS22865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
kpn2146_RS22870	COG0006	proline dipeptidase activity
kpn2146_RS22890	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
kpn2146_RS22895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
kpn2146_RS22915	COG2968	Membrane
kpn2146_RS22930	COG0668	transmembrane transport
kpn2146_RS22935	COG0191	fructose-bisphosphate aldolase activity
kpn2146_RS22950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
kpn2146_RS22955	COG0501	Belongs to the peptidase M48B family
kpn2146_RS22975	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
kpn2146_RS22980	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS23010	COG1414	Transcriptional regulator
kpn2146_RS23015	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS23030	COG2146	nitrite reductase [NAD(P)H] activity
kpn2146_RS23060	COG2814	Major facilitator Superfamily
kpn2146_RS23070	COG2356	endonuclease I
kpn2146_RS23075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
kpn2146_RS23080	COG0189	ligase activity
kpn2146_RS23105	COG2805	Type II/IV secretion system protein
kpn2146_RS23110	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
kpn2146_RS23115	COG0762	integral membrane protein
kpn2146_RS23130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
kpn2146_RS23140	COG3171	Protein conserved in bacteria
kpn2146_RS23150	COG1194	a g-specific adenine glycosylase
kpn2146_RS23165	COG2211	Major facilitator Superfamily
kpn2146_RS23170	COG1982	Orn Lys Arg decarboxylase major
kpn2146_RS23175	COG1811	Na channel or pump
kpn2146_RS23185	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
kpn2146_RS23245	COG3423	Transcriptional regulator
kpn2146_RS23250	COG1278	Cold shock
kpn2146_RS23260	COG3423	Transcriptional regulator
kpn2146_RS23525	COG0626	cystathionine gamma-synthase activity
kpn2146_RS23530	COG0583	DNA-binding transcription factor activity
kpn2146_RS23550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
kpn2146_RS23555	COG0754	glutathionylspermidine amidase activity
kpn2146_RS23570	COG0625	glutathione transferase activity
kpn2146_RS23595	COG2211	Major facilitator Superfamily
kpn2146_RS23600	COG0848	biopolymer transport protein
kpn2146_RS23615	COG0626	cystathionine gamma-synthase activity
kpn2146_RS23620	COG0586	Pfam SNARE associated Golgi protein
kpn2146_RS23625	COG2207	Transcriptional regulator
kpn2146_RS23630	COG1979	alcohol dehydrogenase
kpn2146_RS23635	COG0656	L-ascorbic acid biosynthetic process
kpn2146_RS23645	COG1032	radical SAM domain protein
kpn2146_RS23650	COG2132	Multicopper oxidase
kpn2146_RS23655	COG0204	Acyl-transferase
kpn2146_RS23660	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
kpn2146_RS23665	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
kpn2146_RS23670	COG3111	PFAM Bacterial OB fold (BOF) protein
kpn2146_RS23680	COG0642	Histidine kinase
kpn2146_RS23685	COG2249	NAD(P)H dehydrogenase (quinone) activity
kpn2146_RS23690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
kpn2146_RS23700	COG3150	esterase
kpn2146_RS23705	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
kpn2146_RS23710	COG3151	Protein conserved in bacteria
kpn2146_RS23715	COG0494	nUDIX hydrolase
kpn2146_RS23730	COG0754	glutathionylspermidine amidase activity
kpn2146_RS23735	COG3384	dioxygenase
kpn2146_RS23750	COG2960	long-chain fatty acid transporting porin activity
kpn2146_RS23775	COG3025	triphosphatase activity
kpn2146_RS23780	COG4991	sh3 domain protein
kpn2146_RS23795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
kpn2146_RS23860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
kpn2146_RS23865	COG0358	DNA primase activity
kpn2146_RS23870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
kpn2146_RS23895	COG2197	response regulator
kpn2146_RS23900	COG2198	Histidine kinase
kpn2146_RS23900	COG0784	Response regulator, receiver
kpn2146_RS23900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
kpn2146_RS23900	COG2205	protein histidine kinase activity
kpn2146_RS23910	COG3247	response to pH
kpn2146_RS23980	COG2376	Dihydroxyacetone kinase
kpn2146_RS23985	COG1461	Dihydroxyacetone kinase
kpn2146_RS24000	COG2375	cellular response to nickel ion
kpn2146_RS24010	COG1695	Transcriptional regulator
kpn2146_RS24060	COG1902	pentaerythritol trinitrate reductase activity
kpn2146_RS24060	COG0446	pyridine nucleotide-disulphide oxidoreductase
kpn2146_RS24080	COG1451	nucleotide metabolic process
kpn2146_RS24085	COG0673	inositol 2-dehydrogenase activity
kpn2146_RS24090	COG0861	Integral membrane protein TerC family
kpn2146_RS24105	COG2721	sulfolactate sulfo-lyase activity
kpn2146_RS24115	COG2271	Major facilitator Superfamily
kpn2146_RS24120	COG2186	Transcriptional regulator
kpn2146_RS24125	COG0586	Pfam SNARE associated Golgi protein
kpn2146_RS24135	COG1422	Protein of unknown function (DUF1090)
kpn2146_RS24140	COG4575	ribosome binding
kpn2146_RS24145	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
kpn2146_RS24155	COG2259	Doxx family
kpn2146_RS24160	COG0435	Glutathione S-transferase
kpn2146_RS24165	COG3152	Membrane
kpn2146_RS24170	COG0583	DNA-binding transcription factor activity
kpn2146_RS24175	COG1741	Belongs to the pirin family
kpn2146_RS24205	COG1929	Belongs to the glycerate kinase type-1 family
kpn2146_RS24210	COG2084	Dehydrogenase
kpn2146_RS24220	COG2271	Major facilitator Superfamily
kpn2146_RS24230	COG2721	sulfolactate sulfo-lyase activity
kpn2146_RS24235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
kpn2146_RS24240	COG1349	DNA-binding transcription factor activity
kpn2146_RS24255	COG1105	Belongs to the carbohydrate kinase PfkB family
kpn2146_RS24260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
kpn2146_RS24260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
kpn2146_RS24260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS24265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS24265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS24275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS24280	COG3414	Phosphotransferase system galactitol-specific IIB component
kpn2146_RS24285	COG3775	system Galactitol-specific IIC component
kpn2146_RS24290	COG1063	alcohol dehydrogenase
kpn2146_RS24305	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
kpn2146_RS24325	COG2823	Periplasmic or secreted lipoprotein
kpn2146_RS24330	COG0701	Predicted permease
kpn2146_RS24335	COG0702	epimerase
kpn2146_RS24340	COG0693	protein deglycase activity
kpn2146_RS24355	COG3153	acetyltransferase
kpn2146_RS24360	COG3154	lipid carrier protein
kpn2146_RS24365	COG0826	peptidase U32
kpn2146_RS24370	COG0826	peptidase U32
kpn2146_RS24375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
kpn2146_RS24380	COG0814	amino acid
kpn2146_RS24425	COG0195	Participates in both transcription termination and antitermination
kpn2146_RS24470	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
kpn2146_RS24480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
kpn2146_RS24485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
kpn2146_RS24495	COG1534	Rna-binding protein
kpn2146_RS24505	COG2027	D-alanyl-D-alanine carboxypeptidase
kpn2146_RS24515	COG0697	spore germination
kpn2146_RS24530	COG0142	geranyltranstransferase activity
kpn2146_RS24535	COG3423	Transcriptional regulator
kpn2146_RS24545	COG5007	Belongs to the BolA IbaG family
kpn2146_RS24550	COG3113	response to antibiotic
kpn2146_RS24555	COG2854	intermembrane phospholipid transfer
kpn2146_RS24560	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
kpn2146_RS24565	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
kpn2146_RS24570	COG1127	ABC transporter
kpn2146_RS24575	COG0530	calcium, potassium:sodium antiporter activity
kpn2146_RS24585	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
kpn2146_RS24590	COG3117	lipopolysaccharide transmembrane transporter activity
kpn2146_RS24595	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
kpn2146_RS24600	COG1137	ATPase activity
kpn2146_RS24605	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
kpn2146_RS24610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
kpn2146_RS24615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS24625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
kpn2146_RS24630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
kpn2146_RS24635	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
kpn2146_RS24640	COG5002	protein histidine kinase activity
kpn2146_RS24640	COG2198	Histidine kinase
kpn2146_RS24640	COG0784	Response regulator, receiver
kpn2146_RS24645	COG1312	Catalyzes the dehydration of D-mannonate
kpn2146_RS24655	COG1063	alcohol dehydrogenase
kpn2146_RS24660	COG2271	Major facilitator Superfamily
kpn2146_RS24665	COG1242	4 iron, 4 sulfur cluster binding
kpn2146_RS24670	COG0070	glutamate synthase
kpn2146_RS24670	COG0067	glutamate synthase
kpn2146_RS24670	COG0069	glutamate synthase activity
kpn2146_RS24675	COG0493	'glutamate synthase
kpn2146_RS24685	COG2969	positive regulation of protein catabolic process
kpn2146_RS24690	COG0625	glutathione transferase activity
kpn2146_RS24705	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
kpn2146_RS24710	COG3105	Protein conserved in bacteria
kpn2146_RS24715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
kpn2146_RS24720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
kpn2146_RS24745	COG2732	(Barnase) inhibitor
kpn2146_RS24750	COG1289	transmembrane transporter activity
kpn2146_RS24765	COG0583	DNA-binding transcription factor activity
kpn2146_RS24770	COG0312	modulator of DNA gyrase
kpn2146_RS24775	COG3164	Protein of unknown function
kpn2146_RS24780	COG1530	ribonuclease E activity
kpn2146_RS24790	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
kpn2146_RS24795	COG1792	Involved in formation and maintenance of cell shape
kpn2146_RS24800	COG1077	Cell shape determining protein MreB Mrl
kpn2146_RS24805	COG2200	EAL domain
kpn2146_RS24805	COG2199	diguanylate cyclase activity
kpn2146_RS24830	COG0511	ligase activity, forming carbon-carbon bonds
kpn2146_RS24835	COG0439	Biotin carboxylase
kpn2146_RS24840	COG3924	membrane
kpn2146_RS24845	COG4145	pantothenate transmembrane transporter activity
kpn2146_RS24870	COG4626	Terminase
kpn2146_RS24870	COG1802	Transcriptional regulator
kpn2146_RS24955	COG3561	AntA/AntB antirepressor
kpn2146_RS24970	COG0582	viral genome integration into host DNA
kpn2146_RS24975	COG1309	transcriptional regulator
kpn2146_RS24980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
kpn2146_RS24985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
kpn2146_RS25020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
kpn2146_RS25040	COG0551	DNA topoisomerase type I activity
kpn2146_RS25050	COG0758	DNA mediated transformation
kpn2146_RS25080	COG0789	Transcriptional regulator
kpn2146_RS25095	COG0202	RNA polymerase activity
kpn2146_RS25115	COG0201	protein transport
kpn2146_RS25180	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
kpn2146_RS25195	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
kpn2146_RS25220	COG0051	transcription antitermination factor activity, RNA binding
kpn2146_RS25275	COG2964	Protein conserved in bacteria
kpn2146_RS25280	COG0545	Peptidyl-prolyl cis-trans isomerase
kpn2146_RS25290	COG1047	Peptidyl-prolyl cis-trans
kpn2146_RS25295	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
kpn2146_RS25310	COG0488	(ABC) transporter
kpn2146_RS25320	COG0429	hydrolase of the alpha beta-hydrolase fold
kpn2146_RS25330	COG3954	Phosphoribulokinase
kpn2146_RS25335	COG1765	OsmC-like protein
kpn2146_RS25345	COG1289	transmembrane transporter activity
kpn2146_RS25350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
kpn2146_RS25375	COG0738	Major facilitator superfamily
kpn2146_RS25380	COG0402	S-adenosylhomocysteine deaminase activity
kpn2146_RS25390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
kpn2146_RS25415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
kpn2146_RS25420	COG0338	D12 class N6 adenine-specific DNA methyltransferase
kpn2146_RS25425	COG3266	domain, Protein
kpn2146_RS25440	COG4796	Type ii and iii secretion system protein
kpn2146_RS25465	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
kpn2146_RS25470	COG0494	nUDIX hydrolase
kpn2146_RS25480	COG1011	Hydrolase
kpn2146_RS25485	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
kpn2146_RS25515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
kpn2146_RS25520	COG2183	response to ionizing radiation
kpn2146_RS25525	COG1918	ferrous iron import across plasma membrane
kpn2146_RS25550	COG1040	competence protein
kpn2146_RS25560	COG2610	gluconate transmembrane transporter activity
kpn2146_RS25565	COG1640	4-alpha-glucanotransferase
kpn2146_RS25570	COG0058	SHG alpha-glucan phosphorylase activity
kpn2146_RS25580	COG1349	DNA-binding transcription factor activity
kpn2146_RS25595	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
kpn2146_RS25610	COG0058	SHG alpha-glucan phosphorylase activity
kpn2146_RS25635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
kpn2146_RS25645	COG2610	gluconate transmembrane transporter activity
kpn2146_RS25650	COG3265	gluconokinase activity
kpn2146_RS25655	COG1609	Transcriptional regulator
kpn2146_RS25660	COG1741	Belongs to the pirin family
kpn2146_RS25665	COG0673	inositol 2-dehydrogenase activity
kpn2146_RS25675	COG1247	-acetyltransferase
kpn2146_RS25680	COG0405	Gamma-glutamyltransferase
kpn2146_RS25690	COG0584	glycerophosphoryl diester phosphodiesterase
kpn2146_RS25740	COG0559	Belongs to the binding-protein-dependent transport system permease family
kpn2146_RS25745	COG0683	leucine binding
kpn2146_RS25760	COG0683	leucine binding
kpn2146_RS25770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
kpn2146_RS25785	COG2177	Part of the ABC transporter FtsEX involved in
kpn2146_RS25790	COG2884	Cell division ATP-binding protein ftsE
kpn2146_RS25795	COG0552	protein localization to endoplasmic reticulum
kpn2146_RS25800	COG0742	ribosomal rna small subunit methyltransferase
kpn2146_RS25805	COG3776	membrane
kpn2146_RS25815	COG3714	YhhN family
kpn2146_RS25830	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
kpn2146_RS25840	COG0477	Major facilitator Superfamily
kpn2146_RS25845	COG0628	permease
kpn2146_RS25885	COG3479	Phenolic acid decarboxylase
kpn2146_RS25895	COG0747	negative chemotaxis
kpn2146_RS25900	COG0601	transmembrane transport
kpn2146_RS25905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
kpn2146_RS25915	COG1124	(ABC) transporter
kpn2146_RS25925	COG2239	Acts as a magnesium transporter
kpn2146_RS25930	COG2081	HI0933 family
kpn2146_RS25935	COG0306	phosphate transporter
kpn2146_RS25945	COG0589	response to stress
kpn2146_RS25965	COG0671	phosphoesterase, PA-phosphatase related
kpn2146_RS25970	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
kpn2146_RS25975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
kpn2146_RS25985	COG1454	alcohol dehydrogenase
kpn2146_RS25995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
kpn2146_RS26000	COG1028	Short-chain dehydrogenase reductase Sdr
kpn2146_RS26005	COG0583	DNA-binding transcription factor activity
kpn2146_RS26010	COG1295	ribonuclease BN
kpn2146_RS26015	COG0477	Major facilitator Superfamily
kpn2146_RS26020	COG2982	Protein involved in outer membrane biogenesis
kpn2146_RS26035	COG0612	Peptidase, M16
kpn2146_RS26045	COG2200	EAL domain
kpn2146_RS26045	COG2199	diguanylate cyclase activity
kpn2146_RS26055	COG3118	belongs to the thioredoxin family
kpn2146_RS26055	COG0457	Tetratricopeptide repeat
kpn2146_RS26060	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
kpn2146_RS26065	COG1215	transferase activity, transferring glycosyl groups
kpn2146_RS26095	COG2194	sulfuric ester hydrolase activity
kpn2146_RS26110	COG0457	Tetratricopeptide repeat
kpn2146_RS26115	COG1215	transferase activity, transferring glycosyl groups
kpn2146_RS26140	COG4608	Belongs to the ABC transporter superfamily
kpn2146_RS26145	COG0444	Belongs to the ABC transporter superfamily
kpn2146_RS26150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
kpn2146_RS26155	COG0601	transmembrane transport
kpn2146_RS26160	COG0747	negative chemotaxis
kpn2146_RS26170	COG2801	Transposase and inactivated derivatives
kpn2146_RS26200	COG2223	nitrite transmembrane transporter activity
kpn2146_RS26205	COG5571	outer membrane autotransporter
kpn2146_RS26210	COG2818	Glycosylase
kpn2146_RS26215	COG0456	acetyltransferase
kpn2146_RS26220	COG0243	molybdopterin cofactor binding
kpn2146_RS26225	COG2885	chlorophyll binding
kpn2146_RS26235	COG1609	Transcriptional regulator
kpn2146_RS26245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
kpn2146_RS26265	COG2814	Major facilitator Superfamily
kpn2146_RS26270	COG2944	sequence-specific DNA binding
kpn2146_RS26275	COG1278	Cold shock
kpn2146_RS26305	COG3274	enterobacterial common antigen metabolic process
kpn2146_RS26310	COG4682	membrane
kpn2146_RS26315	COG4682	membrane
kpn2146_RS26330	COG4213	ABC transporter substrate-binding protein
kpn2146_RS26340	COG4214	carbohydrate transport
kpn2146_RS26345	COG2207	Transcriptional regulator
kpn2146_RS26345	COG1609	Transcriptional regulator
kpn2146_RS26350	COG2992	FlgJ-related protein
kpn2146_RS26355	COG0366	Alpha amylase catalytic
kpn2146_RS26360	COG3977	Valine--pyruvate aminotransferase
kpn2146_RS26365	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
kpn2146_RS26370	COG3276	selenocysteine insertion sequence binding
kpn2146_RS26380	COG0625	glutathione transferase activity
kpn2146_RS26385	COG1566	PFAM secretion protein HlyD family protein
kpn2146_RS26405	COG3722	fumarate hydratase activity
kpn2146_RS26425	COG2186	Transcriptional regulator
kpn2146_RS26435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
kpn2146_RS26455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
kpn2146_RS26460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
kpn2146_RS26470	COG4942	peptidase
kpn2146_RS26475	COG2861	carbohydrate metabolic process
kpn2146_RS26480	COG0463	Glycosyl transferase, family 2
kpn2146_RS26490	COG0156	8-amino-7-oxononanoate synthase activity
kpn2146_RS26505	COG0859	PFAM glycosyl transferase family 9
kpn2146_RS26530	COG0859	PFAM glycosyl transferase family 9
kpn2146_RS26540	COG0438	transferase activity, transferring glycosyl groups
kpn2146_RS26545	COG1216	Glycosyl transferase, family 2
kpn2146_RS26550	COG1519	Transferase
kpn2146_RS26585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
kpn2146_RS26610	COG0842	Transport permease protein
kpn2146_RS26615	COG1131	(ABC) transporter
kpn2146_RS26635	COG1561	YicC-like family, N-terminal region
kpn2146_RS26645	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
kpn2146_RS26650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
kpn2146_RS26650	COG2169	Transcriptional regulator
kpn2146_RS26660	COG2860	membrane
kpn2146_RS26680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
kpn2146_RS26685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
kpn2146_RS26690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
kpn2146_RS26695	COG1494	fructose-1,6-bisphosphatase
kpn2146_RS26705	COG3152	Membrane
kpn2146_RS26730	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
kpn2146_RS26735	COG3074	FtsZ-dependent cytokinesis
kpn2146_RS26750	COG0786	glutamate:sodium symporter activity
kpn2146_RS26760	COG2233	PERMEase
kpn2146_RS26765	COG2982	Protein involved in outer membrane biogenesis
kpn2146_RS26770	COG1263	PTS System
kpn2146_RS26770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
kpn2146_RS26775	COG1486	melibiose metabolic process
kpn2146_RS26785	COG1501	Belongs to the glycosyl hydrolase 31 family
kpn2146_RS26790	COG2211	Major facilitator Superfamily
kpn2146_RS26820	COG1064	alcohol dehydrogenase
kpn2146_RS26830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
kpn2146_RS26845	COG1464	Belongs to the NlpA lipoprotein family
kpn2146_RS26870	COG0583	DNA-binding transcription factor activity
kpn2146_RS26915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
kpn2146_RS26925	COG2814	Major facilitator Superfamily
kpn2146_RS26935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
kpn2146_RS26935	COG1263	PTS System
kpn2146_RS26940	COG0697	spore germination
kpn2146_RS26955	COG2828	Protein conserved in bacteria
kpn2146_RS26960	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
kpn2146_RS26965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
kpn2146_RS26970	COG0583	DNA-binding transcription factor activity
kpn2146_RS26975	COG3384	dioxygenase
kpn2146_RS26985	COG1609	Transcriptional regulator
kpn2146_RS26995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
kpn2146_RS26995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
kpn2146_RS27000	COG1447	Phosphotransferase system cellobiose-specific component IIA
kpn2146_RS27005	COG4580	involved in the transport of maltose and maltodextrins
kpn2146_RS27030	COG2188	Transcriptional regulator
kpn2146_RS27070	COG2271	Major facilitator Superfamily
kpn2146_RS27080	COG2197	response regulator
kpn2146_RS27085	COG0440	acetolactate synthase activity
kpn2146_RS27090	COG0028	Belongs to the TPP enzyme family
kpn2146_RS27110	COG2814	Major facilitator Superfamily
kpn2146_RS27115	COG0583	DNA-binding transcription factor activity
kpn2146_RS27125	COG2610	gluconate transmembrane transporter activity
kpn2146_RS27145	COG2149	membrane
kpn2146_RS27160	COG2188	Transcriptional regulator
kpn2146_RS27170	COG3645	SOS response
kpn2146_RS27185	COG5645	(Lipo)protein
kpn2146_RS27190	COG0823	Involved in the tonB-independent uptake of proteins
kpn2146_RS27195	COG2271	Major facilitator Superfamily
kpn2146_RS27205	COG0800	Aldolase
kpn2146_RS27210	COG3734	2-keto-3-deoxy-galactonokinase
kpn2146_RS27215	COG2186	Transcriptional regulator
kpn2146_RS27230	COG0561	phosphatase activity
kpn2146_RS27235	COG0187	DNA topoisomerase II activity
kpn2146_RS27265	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
kpn2146_RS27295	COG2091	lysine biosynthetic process via aminoadipic acid
kpn2146_RS27315	COG0431	NADPH-dependent FMN reductase
kpn2146_RS27320	COG2252	PERMEase
kpn2146_RS27330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
kpn2146_RS27335	COG0363	glucosamine-6-phosphate deaminase activity
kpn2146_RS27340	COG2382	esterase
kpn2146_RS27355	COG0704	Plays a role in the regulation of phosphate uptake
kpn2146_RS27360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
kpn2146_RS27365	COG0581	inorganic phosphate transmembrane transporter activity
kpn2146_RS27370	COG0573	inorganic phosphate transmembrane transporter activity
kpn2146_RS27375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
kpn2146_RS27380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
kpn2146_RS27445	COG3312	ion transport
kpn2146_RS27835	COG3383	formate dehydrogenase (NAD+) activity
kpn2146_RS27835	COG0243	molybdopterin cofactor binding
kpn2146_RS28320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
kpn2146_RS28375	COG1129	ABC transporter
kpn2146_RS28505	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
kpn2146_RS28505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
kpn2146_RS28600	COG3383	formate dehydrogenase (NAD+) activity
kpn2146_RS28600	COG0243	molybdopterin cofactor binding
kpn2146_RS28775	COG2205	protein histidine kinase activity
kpn2146_RS28995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
kpn2146_RS28995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
kpn2146_RS29335	COG0460	homoserine dehydrogenase
kpn2146_RS29335	COG0527	aspartate kinase activity