locus-tag	class	description
CN260_RS00020	COG0187	DNA topoisomerase II activity
CN260_RS00025	COG0561	phosphatase activity
CN260_RS00040	COG2186	Transcriptional regulator
CN260_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
CN260_RS00050	COG0800	Aldolase
CN260_RS00060	COG2271	Major facilitator Superfamily
CN260_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
CN260_RS00070	COG5645	(Lipo)protein
CN260_RS00095	COG2188	Transcriptional regulator
CN260_RS00110	COG2149	membrane
CN260_RS00120	COG0641	radical SAM
CN260_RS00130	COG2610	gluconate transmembrane transporter activity
CN260_RS00135	COG0583	DNA-binding transcription factor activity
CN260_RS00140	COG2814	Major facilitator Superfamily
CN260_RS00165	COG0028	Belongs to the TPP enzyme family
CN260_RS00170	COG0440	acetolactate synthase activity
CN260_RS00175	COG2197	response regulator
CN260_RS00185	COG2271	Major facilitator Superfamily
CN260_RS00230	COG2188	Transcriptional regulator
CN260_RS00255	COG4580	involved in the transport of maltose and maltodextrins
CN260_RS00260	COG1447	Phosphotransferase system cellobiose-specific component IIA
CN260_RS00265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CN260_RS00265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CN260_RS00275	COG1609	Transcriptional regulator
CN260_RS00285	COG3384	dioxygenase
CN260_RS00290	COG0583	DNA-binding transcription factor activity
CN260_RS00295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CN260_RS00300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CN260_RS00305	COG2828	Protein conserved in bacteria
CN260_RS00320	COG0697	spore germination
CN260_RS00325	COG1263	PTS System
CN260_RS00325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CN260_RS00335	COG2814	Major facilitator Superfamily
CN260_RS00345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CN260_RS00380	COG0583	DNA-binding transcription factor activity
CN260_RS00405	COG1464	Belongs to the NlpA lipoprotein family
CN260_RS00420	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CN260_RS00430	COG1064	alcohol dehydrogenase
CN260_RS00465	COG2211	Major facilitator Superfamily
CN260_RS00470	COG1501	Belongs to the glycosyl hydrolase 31 family
CN260_RS00480	COG1486	melibiose metabolic process
CN260_RS00485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CN260_RS00485	COG1263	PTS System
CN260_RS00490	COG2982	Protein involved in outer membrane biogenesis
CN260_RS00495	COG2233	PERMEase
CN260_RS00500	COG0786	glutamate:sodium symporter activity
CN260_RS00520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CN260_RS00545	COG3152	Membrane
CN260_RS00555	COG1494	fructose-1,6-bisphosphatase
CN260_RS00560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CN260_RS00565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CN260_RS00570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CN260_RS00590	COG2860	membrane
CN260_RS00600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CN260_RS00600	COG2169	Transcriptional regulator
CN260_RS00605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CN260_RS00610	COG1561	YicC-like family, N-terminal region
CN260_RS00630	COG1131	(ABC) transporter
CN260_RS00635	COG0842	Transport permease protein
CN260_RS00660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CN260_RS00695	COG1519	Transferase
CN260_RS00700	COG1216	Glycosyl transferase, family 2
CN260_RS00705	COG0438	transferase activity, transferring glycosyl groups
CN260_RS00715	COG0859	PFAM glycosyl transferase family 9
CN260_RS00740	COG0859	PFAM glycosyl transferase family 9
CN260_RS00755	COG0156	8-amino-7-oxononanoate synthase activity
CN260_RS00765	COG0463	Glycosyl transferase, family 2
CN260_RS00770	COG2861	carbohydrate metabolic process
CN260_RS00775	COG4942	peptidase
CN260_RS00785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CN260_RS00790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CN260_RS00810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CN260_RS00820	COG2186	Transcriptional regulator
CN260_RS00840	COG3722	fumarate hydratase activity
CN260_RS00860	COG1566	PFAM secretion protein HlyD family protein
CN260_RS00865	COG0625	glutathione transferase activity
CN260_RS00875	COG3276	selenocysteine insertion sequence binding
CN260_RS00880	COG1414	Transcriptional regulator
CN260_RS00885	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CN260_RS00890	COG3977	Valine--pyruvate aminotransferase
CN260_RS00895	COG0366	Alpha amylase catalytic
CN260_RS00905	COG2992	FlgJ-related protein
CN260_RS00910	COG2207	Transcriptional regulator
CN260_RS00910	COG1609	Transcriptional regulator
CN260_RS00915	COG4214	carbohydrate transport
CN260_RS00925	COG4213	ABC transporter substrate-binding protein
CN260_RS00945	COG4682	membrane
CN260_RS00950	COG4682	membrane
CN260_RS00955	COG3274	enterobacterial common antigen metabolic process
CN260_RS01000	COG1278	Cold shock
CN260_RS01005	COG2944	sequence-specific DNA binding
CN260_RS01010	COG2814	Major facilitator Superfamily
CN260_RS01035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CN260_RS01045	COG1609	Transcriptional regulator
CN260_RS01050	COG2885	chlorophyll binding
CN260_RS01055	COG0243	molybdopterin cofactor binding
CN260_RS01060	COG0456	acetyltransferase
CN260_RS01065	COG2818	Glycosylase
CN260_RS01070	COG5571	outer membrane autotransporter
CN260_RS01075	COG2223	nitrite transmembrane transporter activity
CN260_RS01115	COG0747	negative chemotaxis
CN260_RS01120	COG0601	transmembrane transport
CN260_RS01125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CN260_RS01130	COG0444	Belongs to the ABC transporter superfamily
CN260_RS01135	COG4608	Belongs to the ABC transporter superfamily
CN260_RS01150	COG2894	cell division
CN260_RS01160	COG1215	transferase activity, transferring glycosyl groups
CN260_RS01165	COG0457	Tetratricopeptide repeat
CN260_RS01180	COG2194	sulfuric ester hydrolase activity
CN260_RS01210	COG1215	transferase activity, transferring glycosyl groups
CN260_RS01215	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CN260_RS01220	COG3118	belongs to the thioredoxin family
CN260_RS01220	COG0457	Tetratricopeptide repeat
CN260_RS01225	COG2200	EAL domain
CN260_RS01225	COG2199	diguanylate cyclase activity
CN260_RS01240	COG0612	Peptidase, M16
CN260_RS01255	COG2982	Protein involved in outer membrane biogenesis
CN260_RS01260	COG0477	Major facilitator Superfamily
CN260_RS01265	COG1295	ribonuclease BN
CN260_RS01270	COG0583	DNA-binding transcription factor activity
CN260_RS01275	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS01280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CN260_RS01290	COG1454	alcohol dehydrogenase
CN260_RS01300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CN260_RS01305	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CN260_RS01310	COG0671	phosphoesterase, PA-phosphatase related
CN260_RS01330	COG0589	response to stress
CN260_RS01340	COG0306	phosphate transporter
CN260_RS01345	COG2081	HI0933 family
CN260_RS01350	COG2239	Acts as a magnesium transporter
CN260_RS01360	COG1124	(ABC) transporter
CN260_RS01370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CN260_RS01375	COG0601	transmembrane transport
CN260_RS01380	COG0747	negative chemotaxis
CN260_RS01395	COG3479	Phenolic acid decarboxylase
CN260_RS01435	COG0628	permease
CN260_RS01440	COG0477	Major facilitator Superfamily
CN260_RS01450	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CN260_RS01465	COG3714	YhhN family
CN260_RS01475	COG3776	membrane
CN260_RS01480	COG0742	ribosomal rna small subunit methyltransferase
CN260_RS01485	COG0552	protein localization to endoplasmic reticulum
CN260_RS01490	COG2884	Cell division ATP-binding protein ftsE
CN260_RS01495	COG2177	Part of the ABC transporter FtsEX involved in
CN260_RS01510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CN260_RS01520	COG0683	leucine binding
CN260_RS01535	COG0683	leucine binding
CN260_RS01540	COG0559	Belongs to the binding-protein-dependent transport system permease family
CN260_RS01590	COG0584	glycerophosphoryl diester phosphodiesterase
CN260_RS01600	COG0405	Gamma-glutamyltransferase
CN260_RS01605	COG1247	-acetyltransferase
CN260_RS01615	COG0673	inositol 2-dehydrogenase activity
CN260_RS01620	COG1741	Belongs to the pirin family
CN260_RS01625	COG1609	Transcriptional regulator
CN260_RS01630	COG3265	gluconokinase activity
CN260_RS01635	COG2610	gluconate transmembrane transporter activity
CN260_RS01645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CN260_RS01670	COG0058	SHG alpha-glucan phosphorylase activity
CN260_RS01675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CN260_RS01690	COG1349	DNA-binding transcription factor activity
CN260_RS01705	COG0058	SHG alpha-glucan phosphorylase activity
CN260_RS01710	COG1640	4-alpha-glucanotransferase
CN260_RS01715	COG2610	gluconate transmembrane transporter activity
CN260_RS01725	COG1040	competence protein
CN260_RS01750	COG1918	ferrous iron import across plasma membrane
CN260_RS01755	COG2183	response to ionizing radiation
CN260_RS01760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CN260_RS01785	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CN260_RS01790	COG1011	Hydrolase
CN260_RS01800	COG0494	nUDIX hydrolase
CN260_RS01805	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CN260_RS01830	COG4796	Type ii and iii secretion system protein
CN260_RS01850	COG3266	domain, Protein
CN260_RS01855	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CN260_RS01860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CN260_RS01885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CN260_RS01890	COG0402	S-adenosylhomocysteine deaminase activity
CN260_RS01895	COG0738	Major facilitator superfamily
CN260_RS01920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CN260_RS01925	COG1289	transmembrane transporter activity
CN260_RS01940	COG1765	OsmC-like protein
CN260_RS01945	COG3954	Phosphoribulokinase
CN260_RS01955	COG0429	hydrolase of the alpha beta-hydrolase fold
CN260_RS01965	COG0488	(ABC) transporter
CN260_RS01985	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CN260_RS01990	COG1047	Peptidyl-prolyl cis-trans
CN260_RS02000	COG0545	Peptidyl-prolyl cis-trans isomerase
CN260_RS02005	COG2964	Protein conserved in bacteria
CN260_RS02065	COG0051	transcription antitermination factor activity, RNA binding
CN260_RS02090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CN260_RS02105	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CN260_RS02170	COG0201	protein transport
CN260_RS02195	COG0202	RNA polymerase activity
CN260_RS02210	COG0789	Transcriptional regulator
CN260_RS02215	COG3036	rescue of stalled ribosome
CN260_RS02245	COG0758	DNA mediated transformation
CN260_RS02255	COG0551	DNA topoisomerase type I activity
CN260_RS02275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CN260_RS02315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CN260_RS02320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CN260_RS02325	COG1309	transcriptional regulator
CN260_RS02350	COG4145	pantothenate transmembrane transporter activity
CN260_RS02355	COG3924	membrane
CN260_RS02360	COG0439	Biotin carboxylase
CN260_RS02365	COG0511	ligase activity, forming carbon-carbon bonds
CN260_RS02395	COG2200	EAL domain
CN260_RS02395	COG2199	diguanylate cyclase activity
CN260_RS02405	COG1077	Cell shape determining protein MreB Mrl
CN260_RS02410	COG1792	Involved in formation and maintenance of cell shape
CN260_RS02415	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CN260_RS02425	COG1530	ribonuclease E activity
CN260_RS02430	COG3164	Protein of unknown function
CN260_RS02435	COG0312	modulator of DNA gyrase
CN260_RS02440	COG0583	DNA-binding transcription factor activity
CN260_RS02455	COG1289	transmembrane transporter activity
CN260_RS02460	COG2732	(Barnase) inhibitor
CN260_RS02495	COG0471	metal ion transport
CN260_RS02500	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CN260_RS02505	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CN260_RS02530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CN260_RS02535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CN260_RS02540	COG3105	Protein conserved in bacteria
CN260_RS02545	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CN260_RS02565	COG0625	glutathione transferase activity
CN260_RS02570	COG2969	positive regulation of protein catabolic process
CN260_RS02580	COG0493	'glutamate synthase
CN260_RS02585	COG0067	glutamate synthase
CN260_RS02585	COG0070	glutamate synthase
CN260_RS02585	COG0069	glutamate synthase activity
CN260_RS02595	COG1242	4 iron, 4 sulfur cluster binding
CN260_RS02600	COG2271	Major facilitator Superfamily
CN260_RS02605	COG1063	alcohol dehydrogenase
CN260_RS02610	COG1312	Catalyzes the dehydration of D-mannonate
CN260_RS02615	COG5002	protein histidine kinase activity
CN260_RS02615	COG0784	Response regulator, receiver
CN260_RS02615	COG2198	Histidine kinase
CN260_RS02620	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CN260_RS02625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CN260_RS02630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CN260_RS02640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CN260_RS02645	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CN260_RS02650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CN260_RS02655	COG1137	ATPase activity
CN260_RS02660	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CN260_RS02665	COG3117	lipopolysaccharide transmembrane transporter activity
CN260_RS02670	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CN260_RS02680	COG0530	calcium, potassium:sodium antiporter activity
CN260_RS02690	COG1127	ABC transporter
CN260_RS02695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CN260_RS02700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CN260_RS02705	COG2854	intermembrane phospholipid transfer
CN260_RS02710	COG3113	response to antibiotic
CN260_RS02715	COG5007	Belongs to the BolA IbaG family
CN260_RS02725	COG3423	Transcriptional regulator
CN260_RS02730	COG0142	geranyltranstransferase activity
CN260_RS02745	COG0697	spore germination
CN260_RS02755	COG2027	D-alanyl-D-alanine carboxypeptidase
CN260_RS02765	COG1534	Rna-binding protein
CN260_RS02780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CN260_RS02785	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CN260_RS02795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CN260_RS02835	COG0195	Participates in both transcription termination and antitermination
CN260_RS02885	COG0814	amino acid
CN260_RS02890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CN260_RS02895	COG0826	peptidase U32
CN260_RS02900	COG0826	peptidase U32
CN260_RS02905	COG3154	lipid carrier protein
CN260_RS02910	COG3153	acetyltransferase
CN260_RS02925	COG0693	protein deglycase activity
CN260_RS02930	COG0702	epimerase
CN260_RS02935	COG0701	Predicted permease
CN260_RS02940	COG2823	Periplasmic or secreted lipoprotein
CN260_RS02960	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CN260_RS02965	COG2721	sulfolactate sulfo-lyase activity
CN260_RS02970	COG2271	Major facilitator Superfamily
CN260_RS02980	COG2084	Dehydrogenase
CN260_RS02985	COG1929	Belongs to the glycerate kinase type-1 family
CN260_RS03005	COG1741	Belongs to the pirin family
CN260_RS03010	COG0583	DNA-binding transcription factor activity
CN260_RS03015	COG3152	Membrane
CN260_RS03020	COG0435	Glutathione S-transferase
CN260_RS03025	COG2259	Doxx family
CN260_RS03035	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CN260_RS03040	COG4575	ribosome binding
CN260_RS03045	COG1422	Protein of unknown function (DUF1090)
CN260_RS03055	COG0586	Pfam SNARE associated Golgi protein
CN260_RS03065	COG2186	Transcriptional regulator
CN260_RS03070	COG2271	Major facilitator Superfamily
CN260_RS03080	COG2721	sulfolactate sulfo-lyase activity
CN260_RS03095	COG0861	Integral membrane protein TerC family
CN260_RS03100	COG0673	inositol 2-dehydrogenase activity
CN260_RS03105	COG1451	nucleotide metabolic process
CN260_RS03125	COG0446	pyridine nucleotide-disulphide oxidoreductase
CN260_RS03125	COG1902	pentaerythritol trinitrate reductase activity
CN260_RS03180	COG1695	Transcriptional regulator
CN260_RS03185	COG2375	cellular response to nickel ion
CN260_RS03200	COG1461	Dihydroxyacetone kinase
CN260_RS03205	COG2376	Dihydroxyacetone kinase
CN260_RS03280	COG3247	response to pH
CN260_RS03290	COG0784	Response regulator, receiver
CN260_RS03290	COG2205	protein histidine kinase activity
CN260_RS03290	COG2198	Histidine kinase
CN260_RS03290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CN260_RS03295	COG2197	response regulator
CN260_RS03310	COG0582	viral genome integration into host DNA
CN260_RS03400	COG1802	Transcriptional regulator
CN260_RS03400	COG4626	Terminase
CN260_RS03425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CN260_RS03430	COG0358	DNA primase activity
CN260_RS03435	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CN260_RS03500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CN260_RS03515	COG4991	sh3 domain protein
CN260_RS03520	COG3025	triphosphatase activity
CN260_RS03540	COG2960	long-chain fatty acid transporting porin activity
CN260_RS03555	COG3384	dioxygenase
CN260_RS03560	COG0754	glutathionylspermidine amidase activity
CN260_RS03575	COG0494	nUDIX hydrolase
CN260_RS03580	COG3151	Protein conserved in bacteria
CN260_RS03585	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CN260_RS03590	COG3150	esterase
CN260_RS03600	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CN260_RS03605	COG2249	NAD(P)H dehydrogenase (quinone) activity
CN260_RS03610	COG0642	Histidine kinase
CN260_RS03620	COG3111	PFAM Bacterial OB fold (BOF) protein
CN260_RS03625	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CN260_RS03630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CN260_RS03635	COG0204	Acyl-transferase
CN260_RS03640	COG2132	Multicopper oxidase
CN260_RS03645	COG1032	radical SAM domain protein
CN260_RS03655	COG0656	L-ascorbic acid biosynthetic process
CN260_RS03660	COG1979	alcohol dehydrogenase
CN260_RS03665	COG2207	Transcriptional regulator
CN260_RS03670	COG0586	Pfam SNARE associated Golgi protein
CN260_RS03675	COG0626	cystathionine gamma-synthase activity
CN260_RS03690	COG0848	biopolymer transport protein
CN260_RS03695	COG2211	Major facilitator Superfamily
CN260_RS03720	COG0625	glutathione transferase activity
CN260_RS03730	COG0754	glutathionylspermidine amidase activity
CN260_RS03735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CN260_RS03755	COG0583	DNA-binding transcription factor activity
CN260_RS03760	COG0626	cystathionine gamma-synthase activity
CN260_RS03810	COG1811	Na channel or pump
CN260_RS03820	COG1982	Orn Lys Arg decarboxylase major
CN260_RS03825	COG2211	Major facilitator Superfamily
CN260_RS03840	COG1194	a g-specific adenine glycosylase
CN260_RS03850	COG3171	Protein conserved in bacteria
CN260_RS03865	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CN260_RS03865	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CN260_RS03870	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CN260_RS03875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CN260_RS03890	COG0762	integral membrane protein
CN260_RS03895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CN260_RS03900	COG2805	Type II/IV secretion system protein
CN260_RS03920	COG0189	ligase activity
CN260_RS03925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CN260_RS03930	COG2356	endonuclease I
CN260_RS03940	COG2814	Major facilitator Superfamily
CN260_RS03975	COG0501	Belongs to the peptidase M48B family
CN260_RS03980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CN260_RS03995	COG0191	fructose-bisphosphate aldolase activity
CN260_RS04000	COG0668	transmembrane transport
CN260_RS04010	COG2968	Membrane
CN260_RS04025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CN260_RS04030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CN260_RS04040	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CN260_RS04050	COG0006	proline dipeptidase activity
CN260_RS04055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CN260_RS04060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CN260_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS04090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CN260_RS04110	COG2723	6-phospho-beta-galactosidase activity
CN260_RS04115	COG1737	Transcriptional regulator
CN260_RS04125	COG1272	protein, Hemolysin III
CN260_RS04135	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CN260_RS04145	COG0716	FMN binding
CN260_RS04150	COG4974	Belongs to the 'phage' integrase family
CN260_RS04160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CN260_RS04185	COG4942	peptidase
CN260_RS04200	COG3081	Nucleoid-associated protein
CN260_RS04230	COG0667	Aldo Keto reductase
CN260_RS04235	COG0656	L-ascorbic acid biosynthetic process
CN260_RS04275	COG5002	protein histidine kinase activity
CN260_RS04295	COG3436	PFAM IS66 Orf2 family protein
CN260_RS04300	COG4372	Transposase
CN260_RS04315	COG0778	Nitroreductase
CN260_RS04320	COG2814	Major facilitator Superfamily
CN260_RS04335	COG2814	Major facilitator Superfamily
CN260_RS04350	COG0667	Aldo Keto reductase
CN260_RS04390	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CN260_RS04395	COG1393	Belongs to the ArsC family
CN260_RS04410	COG1538	Outer membrane efflux protein
CN260_RS04415	COG1289	transmembrane transporter activity
CN260_RS04430	COG3592	Divergent 4Fe-4S mono-cluster
CN260_RS04435	COG2388	GCN5-related N-acetyl-transferase
CN260_RS04445	COG3539	Fimbrial protein
CN260_RS04450	COG3539	Fimbrial protein
CN260_RS04455	COG3539	Fimbrial protein
CN260_RS04460	COG3188	usher protein
CN260_RS04465	COG3121	Chaperone
CN260_RS04470	COG3539	Fimbrial protein
CN260_RS04480	COG4974	Belongs to the 'phage' integrase family
CN260_RS04485	COG0582	viral genome integration into host DNA
CN260_RS04495	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CN260_RS04500	COG1846	Transcriptional regulator
CN260_RS04505	COG0697	spore germination
CN260_RS04555	COG0667	Aldo Keto reductase
CN260_RS04560	COG0814	amino acid
CN260_RS04575	COG0183	Belongs to the thiolase family
CN260_RS04585	COG0823	Involved in the tonB-independent uptake of proteins
CN260_RS04590	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS04595	COG2814	Major facilitator Superfamily
CN260_RS04625	COG3842	ATPase activity
CN260_RS04630	COG0395	ABC-type sugar transport system, permease component
CN260_RS04635	COG1175	transmembrane transport
CN260_RS04640	COG1917	Cupin 2, conserved barrel domain protein
CN260_RS04645	COG1794	racemase activity, acting on amino acids and derivatives
CN260_RS04650	COG0583	DNA-binding transcription factor activity
CN260_RS04660	COG1609	Transcriptional regulator
CN260_RS04665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CN260_RS04670	COG2723	6-phospho-beta-galactosidase activity
CN260_RS04675	COG2186	Transcriptional regulator
CN260_RS04685	COG1609	Transcriptional regulator
CN260_RS04710	COG0667	Aldo Keto reductase
CN260_RS04720	COG0861	Integral membrane protein TerC family
CN260_RS04750	COG2165	general secretion pathway protein
CN260_RS04755	COG4795	General secretion pathway protein
CN260_RS04765	COG4967	type IV pilus modification protein PilV
CN260_RS04770	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CN260_RS04775	COG1025	Belongs to the peptidase M16 family
CN260_RS04780	COG1074	ATP-dependent DNA helicase activity
CN260_RS04785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CN260_RS04795	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CN260_RS04795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CN260_RS04800	COG0860	N-Acetylmuramoyl-L-alanine amidase
CN260_RS04805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CN260_RS04835	COG4656	Part of a membrane complex involved in electron transport
CN260_RS04840	COG1454	alcohol dehydrogenase
CN260_RS04840	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS04870	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CN260_RS05035	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CN260_RS05040	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CN260_RS05045	COG2166	iron-sulfur cluster assembly
CN260_RS05050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CN260_RS05060	COG0583	DNA-binding transcription factor activity
CN260_RS05065	COG2363	Small membrane protein
CN260_RS05075	COG1349	DNA-binding transcription factor activity
CN260_RS05095	COG0738	Major facilitator superfamily
CN260_RS05100	COG0235	Class ii aldolase
CN260_RS05105	COG1454	alcohol dehydrogenase
CN260_RS05120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CN260_RS05140	COG2011	ABC-type metal ion transport system permease component
CN260_RS05145	COG1464	Belongs to the NlpA lipoprotein family
CN260_RS05155	COG0477	Major facilitator Superfamily
CN260_RS05165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CN260_RS05170	COG1760	l-serine dehydratase
CN260_RS05175	COG0814	amino acid
CN260_RS05180	COG1611	Belongs to the LOG family
CN260_RS05195	COG3098	single-species biofilm formation
CN260_RS05200	COG0564	pseudouridine synthase activity
CN260_RS05205	COG0716	FMN binding
CN260_RS05210	COG2271	Major facilitator Superfamily
CN260_RS05215	COG4948	Mandelate Racemase Muconate Lactonizing
CN260_RS05220	COG4948	Mandelate Racemase Muconate Lactonizing
CN260_RS05225	COG1929	Belongs to the glycerate kinase type-1 family
CN260_RS05235	COG4999	Histidine kinase
CN260_RS05235	COG3850	Histidine kinase
CN260_RS05235	COG3437	response regulator, receiver
CN260_RS05235	COG2205	protein histidine kinase activity
CN260_RS05245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CN260_RS05250	COG3956	TIGRFAM MazG family protein
CN260_RS05270	COG0602	queuosine metabolic process
CN260_RS05275	COG0720	synthase
CN260_RS05295	COG2234	aminopeptidase activity
CN260_RS05355	COG1388	LysM domain
CN260_RS05355	COG4942	peptidase
CN260_RS05360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CN260_RS05385	COG0163	prenyltransferase activity
CN260_RS05390	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CN260_RS05435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CN260_RS05440	COG4558	Periplasmic binding protein
CN260_RS05445	COG3720	iron ion transport
CN260_RS05465	COG0679	Auxin Efflux Carrier
CN260_RS05480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CN260_RS05485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CN260_RS05490	COG1121	(ABC) transporter
CN260_RS05500	COG1609	Transcriptional regulator
CN260_RS05505	COG1940	carbohydrate kinase activity
CN260_RS05510	COG1447	Phosphotransferase system cellobiose-specific component IIA
CN260_RS05515	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CN260_RS05520	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CN260_RS05525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CN260_RS05530	COG4580	involved in the transport of maltose and maltodextrins
CN260_RS05540	COG2723	6-phospho-beta-galactosidase activity
CN260_RS05550	COG0309	Hydrogenase expression formation protein (HypE)
CN260_RS05555	COG0409	Hydrogenase expression formation protein
CN260_RS05560	COG0298	carbon dioxide binding
CN260_RS05565	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CN260_RS05585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CN260_RS05590	COG0651	ATP synthesis coupled electron transport
CN260_RS05595	COG0650	Formate hydrogenlyase subunit 4
CN260_RS05600	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CN260_RS05600	COG3261	NADH dehydrogenase
CN260_RS05605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CN260_RS05610	COG3260	NADH ubiquinone oxidoreductase 20
CN260_RS05620	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CN260_RS05630	COG2723	6-phospho-beta-galactosidase activity
CN260_RS05635	COG1263	PTS System
CN260_RS05635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CN260_RS05640	COG1609	Transcriptional regulator
CN260_RS05645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CN260_RS05650	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CN260_RS05655	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CN260_RS05685	COG1349	DNA-binding transcription factor activity
CN260_RS05690	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CN260_RS05695	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS05705	COG3732	PTS system glucitol sorbitol-specific
CN260_RS05710	COG3730	PTS system glucitol sorbitol-specific
CN260_RS05715	COG2951	lytic endotransglycosylase activity
CN260_RS05725	COG1121	(ABC) transporter
CN260_RS05730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CN260_RS05740	COG1546	Belongs to the CinA family
CN260_RS05765	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CN260_RS05795	COG2823	Periplasmic or secreted lipoprotein
CN260_RS05800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CN260_RS05805	COG1238	metal cluster binding
CN260_RS05825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CN260_RS05830	COG2814	Major facilitator Superfamily
CN260_RS05835	COG1566	PFAM secretion protein HlyD family protein
CN260_RS05840	COG1846	Transcriptional regulator
CN260_RS05850	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CN260_RS05860	COG4176	ABC-type proline glycine betaine transport system permease component
CN260_RS05875	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CN260_RS05885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CN260_RS05890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CN260_RS05895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CN260_RS05900	COG4575	ribosome binding
CN260_RS05925	COG2916	Histone family protein nucleoid-structuring protein H-NS
CN260_RS05940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CN260_RS05945	COG0640	Transcriptional regulator
CN260_RS05960	COG3284	Transcriptional regulator
CN260_RS05970	COG3539	Fimbrial protein
CN260_RS05975	COG3121	Chaperone
CN260_RS05995	COG3188	usher protein
CN260_RS06005	COG3539	Fimbrial protein
CN260_RS06010	COG2197	response regulator
CN260_RS06025	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS06035	COG0235	Class ii aldolase
CN260_RS06040	COG1126	abc transporter atp-binding protein
CN260_RS06045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CN260_RS06080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CN260_RS06085	COG3708	Transcriptional regulator
CN260_RS06085	COG2207	Transcriptional regulator
CN260_RS06105	COG0662	Cupin 2, conserved barrel domain protein
CN260_RS06115	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS06120	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CN260_RS06125	COG0210	DNA helicase
CN260_RS06145	COG0706	membrane insertase activity
CN260_RS06165	COG2867	negative regulation of translational initiation
CN260_RS06180	COG0497	DNA recombination
CN260_RS06200	COG4536	flavin adenine dinucleotide binding
CN260_RS06205	COG4137	Cytochrome C assembly protein
CN260_RS06210	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CN260_RS06245	COG2885	chlorophyll binding
CN260_RS06250	COG2199	diguanylate cyclase activity
CN260_RS06260	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CN260_RS06265	COG0287	Prephenate dehydrogenase
CN260_RS06265	COG1605	Chorismate mutase
CN260_RS06275	COG0077	Prephenate dehydratase
CN260_RS06275	COG1605	Chorismate mutase
CN260_RS06285	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CN260_RS06290	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CN260_RS06305	COG0542	response to heat
CN260_RS06330	COG0477	Major facilitator Superfamily
CN260_RS06335	COG5544	Lipoprotein
CN260_RS06340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CN260_RS06350	COG3148	PFAM DTW domain containing protein
CN260_RS06355	COG3118	belongs to the thioredoxin family
CN260_RS06360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CN260_RS06375	COG0513	Belongs to the DEAD box helicase family
CN260_RS06385	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CN260_RS06395	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CN260_RS06400	COG3026	antisigma factor binding
CN260_RS06405	COG3086	response to oxidative stress
CN260_RS06440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CN260_RS06490	COG1484	DNA-dependent DNA replication
CN260_RS06565	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CN260_RS06570	COG0484	heat shock protein binding
CN260_RS06630	COG3728	DNA packaging
CN260_RS06630	COG5484	DNA packaging
CN260_RS06715	COG1196	nuclear chromosome segregation
CN260_RS06770	COG0681	Belongs to the peptidase S26 family
CN260_RS06790	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CN260_RS06800	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CN260_RS06805	COG1737	Transcriptional regulator
CN260_RS06810	COG0560	Phosphoserine phosphatase
CN260_RS06825	COG0047	phosphoribosylformylglycinamidine synthase activity
CN260_RS06825	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CN260_RS06830	COG2205	protein histidine kinase activity
CN260_RS06835	COG3170	Tfp pilus assembly protein FimV
CN260_RS06840	COG2204	response regulator
CN260_RS06845	COG0347	Belongs to the P(II) protein family
CN260_RS06850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CN260_RS06850	COG1017	nitric oxide dioxygenase activity
CN260_RS06865	COG2259	Doxx family
CN260_RS06870	COG1940	carbohydrate kinase activity
CN260_RS06875	COG0457	Tetratricopeptide repeat
CN260_RS06880	COG0477	Major facilitator Superfamily
CN260_RS06880	COG2814	Major facilitator Superfamily
CN260_RS06885	COG2017	converts alpha-aldose to the beta-anomer
CN260_RS06890	COG2814	Major facilitator Superfamily
CN260_RS06895	COG3711	transcriptional antiterminator
CN260_RS06900	COG3683	transport system, periplasmic component
CN260_RS06905	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CN260_RS06935	COG0822	iron-sulfur transferase activity
CN260_RS06955	COG0633	Ferredoxin
CN260_RS06960	COG2975	iron-sulfur cluster assembly
CN260_RS06980	COG2897	thiosulfate sulfurtransferase activity
CN260_RS06985	COG2373	Large extracellular alpha-helical protein
CN260_RS06990	COG4953	penicillin-binding protein 1C
CN260_RS07020	COG2976	Protein conserved in bacteria
CN260_RS07040	COG1645	bacterial-type flagellum-dependent swarming motility
CN260_RS07050	COG0517	IMP dehydrogenase activity
CN260_RS07050	COG0516	GMP reductase activity
CN260_RS07095	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CN260_RS07125	COG3756	Protein conserved in bacteria
CN260_RS07185	COG5484	DNA packaging
CN260_RS07185	COG3728	DNA packaging
CN260_RS07330	COG3179	chitinase
CN260_RS07375	COG2200	EAL domain
CN260_RS07390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CN260_RS07405	COG2723	6-phospho-beta-galactosidase activity
CN260_RS07415	COG2233	PERMEase
CN260_RS07430	COG1393	Belongs to the ArsC family
CN260_RS07435	COG4783	chaperone-mediated protein folding
CN260_RS07440	COG0628	permease
CN260_RS07445	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CN260_RS07450	COG2716	regulation of RNA biosynthetic process
CN260_RS07460	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CN260_RS07470	COG2321	neutral zinc metallopeptidase
CN260_RS07475	COG1444	tRNA N-acetyltransferase activity
CN260_RS07480	COG0400	carboxylic ester hydrolase activity
CN260_RS07495	COG1393	Belongs to the ArsC family
CN260_RS07505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CN260_RS07515	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CN260_RS07515	COG0493	'glutamate synthase
CN260_RS07525	COG5342	invasion associated locus B
CN260_RS07530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CN260_RS07535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CN260_RS07545	COG4810	utilization protein
CN260_RS07635	COG0860	N-Acetylmuramoyl-L-alanine amidase
CN260_RS07655	COG2837	iron assimilation
CN260_RS07665	COG4150	thiosulfate binding
CN260_RS07670	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CN260_RS07675	COG4208	sulfate ABC transporter
CN260_RS07680	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CN260_RS07690	COG4319	ketosteroid isomerase
CN260_RS07725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CN260_RS07745	COG3530	Putative quorum-sensing-regulated virulence factor
CN260_RS07750	COG0385	Bile acid
CN260_RS07755	COG0583	DNA-binding transcription factor activity
CN260_RS07795	COG3415	Transposase
CN260_RS07800	COG3415	Transposase
CN260_RS07815	COG2200	EAL domain
CN260_RS07815	COG2199	diguanylate cyclase activity
CN260_RS07820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CN260_RS07835	COG0667	Aldo Keto reductase
CN260_RS07840	COG3961	Belongs to the TPP enzyme family
CN260_RS07855	COG3279	Response regulator of the LytR AlgR family
CN260_RS07860	COG3275	phosphorelay sensor kinase activity
CN260_RS07870	COG0436	Aminotransferase
CN260_RS07880	COG2807	transmembrane transport
CN260_RS07885	COG0590	tRNA wobble adenosine to inosine editing
CN260_RS07890	COG0583	DNA-binding transcription factor activity
CN260_RS07910	COG2116	formate transmembrane transporter activity
CN260_RS07915	COG2853	Lipoprotein
CN260_RS07930	COG3691	Protein conserved in bacteria
CN260_RS07945	COG2062	phosphohistidine phosphatase, SixA
CN260_RS07970	COG0730	response to heat
CN260_RS07975	COG3101	peptidyl-lysine hydroxylation
CN260_RS07990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CN260_RS08010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CN260_RS08020	COG0586	Pfam SNARE associated Golgi protein
CN260_RS08030	COG0285	dihydrofolate synthase activity
CN260_RS08035	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CN260_RS08040	COG1286	toxin biosynthetic process
CN260_RS08045	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CN260_RS08050	COG0163	prenyltransferase activity
CN260_RS08070	COG4160	amino acid transport
CN260_RS08075	COG4598	ABC transporter
CN260_RS08085	COG1090	epimerase
CN260_RS08090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CN260_RS08095	COG0625	glutathione transferase activity
CN260_RS08100	COG0625	glutathione transferase activity
CN260_RS08105	COG0622	Phosphoesterase
CN260_RS08110	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CN260_RS08115	COG0857	belongs to the CobB CobQ family
CN260_RS08115	COG0280	phosphate acetyltransferase
CN260_RS08135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CN260_RS08140	COG0490	domain, Protein
CN260_RS08140	COG0471	metal ion transport
CN260_RS08150	COG0436	Aminotransferase
CN260_RS08155	COG0583	DNA-binding transcription factor activity
CN260_RS08210	COG0839	Belongs to the complex I subunit 6 family
CN260_RS08220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CN260_RS08225	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CN260_RS08240	COG2153	protein acetylation
CN260_RS08245	COG1169	isochorismate synthase
CN260_RS08270	COG0318	PFAM AMP-dependent synthetase and ligase
CN260_RS08280	COG5464	transposase or invertase
CN260_RS08300	COG1414	Transcriptional regulator
CN260_RS08310	COG2271	Major facilitator Superfamily
CN260_RS08320	COG0247	lactate metabolic process
CN260_RS08330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CN260_RS08335	COG2271	Major facilitator Superfamily
CN260_RS08340	COG0584	glycerophosphoryl diester phosphodiesterase
CN260_RS08350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CN260_RS08380	COG0784	Response regulator, receiver
CN260_RS08380	COG2205	protein histidine kinase activity
CN260_RS08390	COG0642	Histidine kinase
CN260_RS08390	COG2198	Histidine kinase
CN260_RS08415	COG2169	Transcriptional regulator
CN260_RS08415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CN260_RS08420	COG3145	DNA-N1-methyladenine dioxygenase activity
CN260_RS08425	COG4615	Cyclic peptide transporter
CN260_RS08430	COG2239	Acts as a magnesium transporter
CN260_RS08435	COG0659	secondary active sulfate transmembrane transporter activity
CN260_RS08450	COG0628	permease
CN260_RS08480	COG1349	DNA-binding transcription factor activity
CN260_RS08485	COG0494	nUDIX hydrolase
CN260_RS08505	COG1061	Type III restriction enzyme res subunit
CN260_RS08510	COG1187	pseudouridine synthase activity
CN260_RS08515	COG2814	Major facilitator Superfamily
CN260_RS08525	COG4172	Belongs to the ABC transporter superfamily
CN260_RS08530	COG4239	(ABC) transporter, permease
CN260_RS08535	COG4174	ABC transporter (Permease)
CN260_RS08540	COG4166	transmembrane transport
CN260_RS08545	COG2200	EAL domain
CN260_RS08550	COG0791	NLP P60 protein
CN260_RS08555	COG0671	phosphoesterase, PA-phosphatase related
CN260_RS08560	COG0523	cobalamin synthesis protein
CN260_RS08565	COG0246	Mannitol dehydrogenase
CN260_RS08570	COG1312	Catalyzes the dehydration of D-mannonate
CN260_RS08590	COG2814	Major facilitator Superfamily
CN260_RS08600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CN260_RS08600	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CN260_RS08605	COG1105	Belongs to the carbohydrate kinase PfkB family
CN260_RS08610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CN260_RS08610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CN260_RS08610	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CN260_RS08620	COG2855	membrane
CN260_RS08630	COG0583	DNA-binding transcription factor activity
CN260_RS08635	COG0833	amino acid
CN260_RS08645	COG4771	TonB-dependent receptor
CN260_RS08660	COG2311	Membrane
CN260_RS08675	COG1129	ABC transporter
CN260_RS08685	COG2949	membrane
CN260_RS08700	COG1346	cytolysis
CN260_RS08710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CN260_RS08715	COG3659	wide pore channel activity
CN260_RS08730	COG2723	6-phospho-beta-galactosidase activity
CN260_RS08735	COG1538	Outer membrane efflux protein
CN260_RS08740	COG0586	Pfam SNARE associated Golgi protein
CN260_RS08750	COG1686	Belongs to the peptidase S11 family
CN260_RS08760	COG0277	FAD linked oxidase domain protein
CN260_RS08765	COG1472	Belongs to the glycosyl hydrolase 3 family
CN260_RS08770	COG1732	Glycine betaine
CN260_RS08775	COG1174	glycine betaine transport
CN260_RS08780	COG1125	glycine betaine transport
CN260_RS08785	COG1174	glycine betaine transport
CN260_RS08795	COG3275	phosphorelay sensor kinase activity
CN260_RS08805	COG4807	Protein conserved in bacteria
CN260_RS08825	COG5455	response to cobalt ion
CN260_RS08830	COG0583	DNA-binding transcription factor activity
CN260_RS08835	COG2252	PERMEase
CN260_RS08845	COG0583	DNA-binding transcription factor activity
CN260_RS08860	COG0351	phosphomethylpyrimidine kinase
CN260_RS08865	COG1830	Aldolase
CN260_RS08875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CN260_RS08900	COG1070	Carbohydrate kinase
CN260_RS08910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CN260_RS08915	COG4948	Mandelate Racemase Muconate Lactonizing
CN260_RS08920	COG0747	negative chemotaxis
CN260_RS08925	COG0601	transmembrane transport
CN260_RS08930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CN260_RS08935	COG0444	Belongs to the ABC transporter superfamily
CN260_RS08940	COG4608	Belongs to the ABC transporter superfamily
CN260_RS08950	COG0826	peptidase U32
CN260_RS08955	COG0745	RESPONSE REGULATOR receiver
CN260_RS08960	COG2205	protein histidine kinase activity
CN260_RS08985	COG1301	dicarboxylic acid transport
CN260_RS09000	COG5002	protein histidine kinase activity
CN260_RS09005	COG0443	Heat shock 70 kDa protein
CN260_RS09015	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CN260_RS09030	COG2982	Protein involved in outer membrane biogenesis
CN260_RS09035	COG1253	flavin adenine dinucleotide binding
CN260_RS09095	COG1216	Glycosyl transferase, family 2
CN260_RS09110	COG0562	UDP-galactopyranose mutase
CN260_RS09115	COG1216	Glycosyl transferase, family 2
CN260_RS09140	COG1088	dTDP-glucose 4,6-dehydratase activity
CN260_RS09210	COG0438	transferase activity, transferring glycosyl groups
CN260_RS09235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CN260_RS09265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CN260_RS09270	COG0583	DNA-binding transcription factor activity
CN260_RS09280	COG0531	amino acid
CN260_RS09285	COG0640	Transcriptional regulator
CN260_RS09290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CN260_RS09295	COG2925	Exonuclease
CN260_RS09310	COG1289	transmembrane transporter activity
CN260_RS09330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CN260_RS09340	COG1942	4-Oxalocrotonate Tautomerase
CN260_RS09345	COG0583	DNA-binding transcription factor activity
CN260_RS09350	COG0095	Lipoate-protein ligase
CN260_RS09355	COG0477	Major facilitator Superfamily
CN260_RS09370	COG5001	Diguanylate cyclase
CN260_RS09370	COG3300	MHYT domain
CN260_RS09380	COG3615	Tellurite resistance protein tehB
CN260_RS09405	COG3706	GGDEF domain
CN260_RS09425	COG0534	Mate efflux family protein
CN260_RS09435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CN260_RS09455	COG0604	alcohol dehydrogenase
CN260_RS09460	COG1309	transcriptional regulator
CN260_RS09465	COG0025	NhaP-type Na H and K H
CN260_RS09510	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CN260_RS09525	COG1418	mRNA catabolic process
CN260_RS09530	COG0270	DNA (cytosine-5-)-methyltransferase activity
CN260_RS09535	COG3727	T/G mismatch-specific endonuclease activity
CN260_RS09540	COG0697	spore germination
CN260_RS09545	COG2354	Protein conserved in bacteria
CN260_RS09575	COG0366	Alpha amylase catalytic
CN260_RS09580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CN260_RS09590	COG0765	amino acid transport
CN260_RS09595	COG1126	abc transporter atp-binding protein
CN260_RS09600	COG2197	response regulator
CN260_RS09610	COG2197	response regulator
CN260_RS09645	COG3012	SEC-C Motif Domain Protein
CN260_RS09645	COG3318	Belongs to the UPF0149 family
CN260_RS09650	COG0814	amino acid
CN260_RS09660	COG1528	Iron-storage protein
CN260_RS09675	COG0477	Major facilitator Superfamily
CN260_RS09685	COG2211	Major facilitator Superfamily
CN260_RS09695	COG1528	Iron-storage protein
CN260_RS09705	COG1879	ABC-type sugar transport system periplasmic component
CN260_RS09715	COG1172	Belongs to the binding-protein-dependent transport system permease family
CN260_RS09740	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CN260_RS09750	COG3102	Protein conserved in bacteria
CN260_RS09770	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CN260_RS09775	COG1801	Protein of unknown function DUF72
CN260_RS09780	COG1335	isochorismatase
CN260_RS09790	COG0494	nUDIX hydrolase
CN260_RS09815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CN260_RS09825	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CN260_RS09830	COG0739	heme binding
CN260_RS09835	COG1560	Kdo2-lipid A biosynthetic process
CN260_RS09845	COG1737	Transcriptional regulator
CN260_RS09860	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CN260_RS09865	COG0129	dihydroxy-acid dehydratase activity
CN260_RS09870	COG0800	Aldolase
CN260_RS09880	COG3141	response to X-ray
CN260_RS09885	COG2979	Protein of unknown function (DUF533)
CN260_RS09890	COG1770	oligopeptidase
CN260_RS09895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CN260_RS09905	COG2372	response to copper ion
CN260_RS09910	COG1276	copper resistance
CN260_RS09925	COG2990	Protein conserved in bacteria
CN260_RS09950	COG3008	intermembrane lipid transfer
CN260_RS09955	COG2995	paraquat-inducible protein a
CN260_RS09960	COG1956	GAF domain-containing protein
CN260_RS09980	COG2814	Major facilitator Superfamily
CN260_RS09990	COG1414	Transcriptional regulator
CN260_RS10030	COG0768	penicillin binding
CN260_RS10035	COG2226	methyltransferase
CN260_RS10050	COG3716	PTS system mannose fructose sorbose family IID component
CN260_RS10055	COG3715	PTS system
CN260_RS10060	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CN260_RS10060	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CN260_RS10065	COG1253	flavin adenine dinucleotide binding
CN260_RS10070	COG2200	EAL domain
CN260_RS10075	COG1760	l-serine dehydratase
CN260_RS10095	COG0251	oxidation-reduction process
CN260_RS10100	COG1199	ATP-dependent helicase activity
CN260_RS10110	COG3065	identical protein binding
CN260_RS10120	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CN260_RS10130	COG2894	cell division
CN260_RS10145	COG0179	Fumarylacetoacetate (FAA) hydrolase
CN260_RS10175	COG2719	SpoVR family
CN260_RS10195	COG1619	proteins homologs of microcin C7 resistance protein MccF
CN260_RS10205	COG4774	siderophore transport
CN260_RS10220	COG2308	Evidence 4 Homologs of previously reported genes of
CN260_RS10260	COG0583	DNA-binding transcription factor activity
CN260_RS10265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CN260_RS10280	COG1882	Formate acetyltransferase
CN260_RS10310	COG0583	DNA-binding transcription factor activity
CN260_RS10345	COG0582	viral genome integration into host DNA
CN260_RS10410	COG1846	Transcriptional regulator
CN260_RS10450	COG4725	Belongs to the MT-A70-like family
CN260_RS10480	COG3772	lysozyme
CN260_RS10505	COG3422	double-strand break repair
CN260_RS10510	COG1783	phage Terminase large subunit
CN260_RS10515	COG3567	Phage-associated protein, HI1409 family
CN260_RS10675	COG3122	Protein conserved in bacteria
CN260_RS10700	COG2885	chlorophyll binding
CN260_RS10780	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CN260_RS10860	COG0012	GTP binding
CN260_RS10880	COG0659	secondary active sulfate transmembrane transporter activity
CN260_RS10915	COG2890	protein-(glutamine-N5) methyltransferase activity
CN260_RS10935	COG0387	Pfam Sodium calcium exchanger
CN260_RS10940	COG4572	Cation transport regulator
CN260_RS10945	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CN260_RS10955	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CN260_RS10960	COG3707	response regulator
CN260_RS10965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CN260_RS10975	COG1116	anion transmembrane transporter activity
CN260_RS10980	COG2146	nitrite reductase [NAD(P)H] activity
CN260_RS10980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CN260_RS10985	COG0243	molybdopterin cofactor binding
CN260_RS10990	COG4932	domain protein
CN260_RS10995	COG2197	response regulator
CN260_RS11000	COG3850	Histidine kinase
CN260_RS11005	COG2223	nitrite transmembrane transporter activity
CN260_RS11010	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CN260_RS11015	COG1140	nitrate reductase beta subunit
CN260_RS11020	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CN260_RS11025	COG2181	nitrate reductase activity
CN260_RS11035	COG1522	sequence-specific DNA binding
CN260_RS11070	COG0788	formyltetrahydrofolate deformylase activity
CN260_RS11080	COG1752	Esterase of the alpha-beta hydrolase superfamily
CN260_RS11085	COG0745	RESPONSE REGULATOR receiver
CN260_RS11090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CN260_RS11095	COG2916	Histone family protein nucleoid-structuring protein H-NS
CN260_RS11100	COG1435	thymidine kinase activity
CN260_RS11105	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS11105	COG1454	alcohol dehydrogenase
CN260_RS11115	COG2095	MarC family integral membrane protein
CN260_RS11120	COG4166	transmembrane transport
CN260_RS11125	COG0601	transmembrane transport
CN260_RS11130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CN260_RS11135	COG0444	Belongs to the ABC transporter superfamily
CN260_RS11145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CN260_RS11165	COG2353	YceI-like domain
CN260_RS11170	COG2350	Protein conserved in bacteria
CN260_RS11180	COG3001	Fructosamine kinase
CN260_RS11190	COG1105	Belongs to the carbohydrate kinase PfkB family
CN260_RS11195	COG3137	Salt-induced outer membrane protein
CN260_RS11235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CN260_RS11235	COG0072	phenylalanine-tRNA ligase activity
CN260_RS11255	COG0583	DNA-binding transcription factor activity
CN260_RS11275	COG0386	Belongs to the glutathione peroxidase family
CN260_RS11285	COG0791	NLP P60 protein
CN260_RS11295	COG4256	Hemin uptake protein
CN260_RS11300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CN260_RS11310	COG0574	Belongs to the PEP-utilizing enzyme family
CN260_RS11310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CN260_RS11320	COG0628	permease
CN260_RS11325	COG0277	FAD linked oxidase domain protein
CN260_RS11325	COG0247	lactate metabolic process
CN260_RS11330	COG2050	protein possibly involved in aromatic compounds catabolism
CN260_RS11335	COG2261	transglycosylase associated protein
CN260_RS11355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CN260_RS11365	COG1120	ATPase activity
CN260_RS11370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CN260_RS11380	COG0583	DNA-binding transcription factor activity
CN260_RS11405	COG1304	FMN binding
CN260_RS11410	COG1309	transcriptional regulator
CN260_RS11425	COG0316	Belongs to the HesB IscA family
CN260_RS11430	COG0719	Fe-S assembly protein
CN260_RS11435	COG0396	ATPase activity
CN260_RS11440	COG0719	Fe-S assembly protein
CN260_RS11455	COG1376	ErfK ybiS ycfS ynhG family protein
CN260_RS11480	COG1309	transcriptional regulator
CN260_RS11485	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CN260_RS11485	COG1082	Xylose isomerase domain protein TIM barrel
CN260_RS11490	COG2271	Major facilitator Superfamily
CN260_RS11495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CN260_RS11505	COG1120	ATPase activity
CN260_RS11510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CN260_RS11515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CN260_RS11520	COG1414	Transcriptional regulator
CN260_RS11555	COG2814	Major facilitator Superfamily
CN260_RS11575	COG0583	DNA-binding transcription factor activity
CN260_RS11580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CN260_RS11600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CN260_RS11605	COG1116	anion transmembrane transporter activity
CN260_RS11610	COG4774	siderophore transport
CN260_RS11615	COG1120	ATPase activity
CN260_RS11620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CN260_RS11625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CN260_RS11645	COG0765	amino acid transport
CN260_RS11650	COG1126	abc transporter atp-binding protein
CN260_RS11680	COG1473	amidohydrolase
CN260_RS11685	COG3383	formate dehydrogenase (NAD+) activity
CN260_RS11690	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CN260_RS11705	COG1175	transmembrane transport
CN260_RS11735	COG4133	protoheme IX ABC transporter activity
CN260_RS11740	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CN260_RS11745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CN260_RS11760	COG1138	Cytochrome C-type biogenesis protein
CN260_RS11765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CN260_RS11770	COG4235	cytochrome complex assembly
CN260_RS11770	COG3088	subunit of a heme lyase
CN260_RS11805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CN260_RS11840	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS11845	COG2610	gluconate transmembrane transporter activity
CN260_RS11850	COG1250	3-hydroxyacyl-CoA dehydrogenase
CN260_RS11860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CN260_RS11870	COG0583	DNA-binding transcription factor activity
CN260_RS11900	COG2814	Major facilitator Superfamily
CN260_RS11915	COG0277	FAD linked oxidase domain protein
CN260_RS11920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CN260_RS11945	COG0402	S-adenosylhomocysteine deaminase activity
CN260_RS11990	COG3321	synthase
CN260_RS11990	COG0604	alcohol dehydrogenase
CN260_RS11990	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS12020	COG4608	Belongs to the ABC transporter superfamily
CN260_RS12025	COG0444	Belongs to the ABC transporter superfamily
CN260_RS12050	COG0346	lactoylglutathione lyase activity
CN260_RS12055	COG1349	DNA-binding transcription factor activity
CN260_RS12085	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CN260_RS12135	COG0307	riboflavin synthase, alpha
CN260_RS12140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CN260_RS12145	COG2814	Major facilitator Superfamily
CN260_RS12150	COG0583	DNA-binding transcription factor activity
CN260_RS12165	COG2814	Major facilitator Superfamily
CN260_RS12180	COG0791	NLP P60 protein
CN260_RS12185	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CN260_RS12195	COG0346	lactoylglutathione lyase activity
CN260_RS12200	COG1902	pentaerythritol trinitrate reductase activity
CN260_RS12205	COG1309	transcriptional regulator
CN260_RS12210	COG3313	Fe-S protein
CN260_RS12215	COG4989	oxidoreductase activity
CN260_RS12220	COG2032	superoxide dismutase activity
CN260_RS12225	COG1289	transmembrane transporter activity
CN260_RS12230	COG1566	PFAM secretion protein HlyD family protein
CN260_RS12245	COG3706	GGDEF domain
CN260_RS12260	COG3895	Periplasmic Protein
CN260_RS12275	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CN260_RS12280	COG0625	glutathione transferase activity
CN260_RS12295	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CN260_RS12305	COG4659	FMN binding
CN260_RS12340	COG2723	6-phospho-beta-galactosidase activity
CN260_RS12350	COG0673	inositol 2-dehydrogenase activity
CN260_RS12360	COG2814	Major facilitator Superfamily
CN260_RS12380	COG3038	cytochrome b561
CN260_RS12400	COG0583	DNA-binding transcription factor activity
CN260_RS12405	COG3485	protocatechuate 3,4-dioxygenase
CN260_RS12410	COG3485	protocatechuate 3,4-dioxygenase
CN260_RS12415	COG5383	Protein conserved in bacteria
CN260_RS12420	COG2272	Belongs to the type-B carboxylesterase lipase family
CN260_RS12435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CN260_RS12440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CN260_RS12445	COG1275	C4-dicarboxylate transporter malic acid transport protein
CN260_RS12450	COG0500	methyltransferase
CN260_RS12470	COG2207	Transcriptional regulator
CN260_RS12470	COG3708	Transcriptional regulator
CN260_RS12475	COG3135	benzoate transporter
CN260_RS12480	COG1396	sequence-specific DNA binding
CN260_RS12490	COG0826	peptidase U32
CN260_RS12510	COG1294	oxidase, subunit
CN260_RS12515	COG1271	oxidase subunit
CN260_RS12520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CN260_RS12525	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CN260_RS12530	COG3842	ATPase activity
CN260_RS12535	COG1176	ABC-type spermidine putrescine transport system, permease component I
CN260_RS12540	COG1177	transmembrane transport
CN260_RS12545	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS12575	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS12580	COG0747	negative chemotaxis
CN260_RS12590	COG3238	Protein conserved in bacteria
CN260_RS12595	COG1247	-acetyltransferase
CN260_RS12605	COG2130	NADP-dependent
CN260_RS12620	COG3691	Protein conserved in bacteria
CN260_RS12625	COG1228	amidohydrolase
CN260_RS12630	COG4772	TonB-dependent receptor
CN260_RS12655	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CN260_RS12660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CN260_RS12665	COG1473	amidohydrolase
CN260_RS12670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CN260_RS12675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CN260_RS12685	COG0765	amino acid transport
CN260_RS12690	COG1126	abc transporter atp-binding protein
CN260_RS12700	COG0625	glutathione transferase activity
CN260_RS12715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CN260_RS12720	COG3842	ATPase activity
CN260_RS12725	COG1840	ABC-type Fe3 transport system, periplasmic component
CN260_RS12730	COG1178	ABC-type Fe3 transport system permease component
CN260_RS12735	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CN260_RS12740	COG2181	nitrate reductase activity
CN260_RS12745	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CN260_RS12750	COG1140	nitrate reductase beta subunit
CN260_RS12755	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CN260_RS12775	COG1414	Transcriptional regulator
CN260_RS12780	COG4948	Mandelate Racemase Muconate Lactonizing
CN260_RS12785	COG4829	muconolactone delta-isomerase
CN260_RS12790	COG3485	protocatechuate 3,4-dioxygenase
CN260_RS12800	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CN260_RS12820	COG3383	formate dehydrogenase (NAD+) activity
CN260_RS12820	COG0243	molybdopterin cofactor binding
CN260_RS12825	COG3383	formate dehydrogenase (NAD+) activity
CN260_RS12825	COG0243	molybdopterin cofactor binding
CN260_RS12830	COG0437	4 iron, 4 sulfur cluster binding
CN260_RS12835	COG2864	formate dehydrogenase
CN260_RS12850	COG2326	polyphosphate kinase activity
CN260_RS12860	COG2814	Major facilitator Superfamily
CN260_RS12870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CN260_RS12880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CN260_RS12890	COG0747	negative chemotaxis
CN260_RS12895	COG1064	alcohol dehydrogenase
CN260_RS12910	COG0488	(ABC) transporter
CN260_RS12950	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS12955	COG3729	General stress protein
CN260_RS12970	COG3685	Protein conserved in bacteria
CN260_RS12980	COG0366	Alpha amylase catalytic
CN260_RS12990	COG2323	membrane
CN260_RS13000	COG3111	PFAM Bacterial OB fold (BOF) protein
CN260_RS13005	COG1764	response to oxidative stress
CN260_RS13030	COG3781	membrane
CN260_RS13035	COG0243	molybdopterin cofactor binding
CN260_RS13040	COG0583	DNA-binding transcription factor activity
CN260_RS13045	COG2814	Major facilitator Superfamily
CN260_RS13055	COG1285	pathogenesis
CN260_RS13060	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CN260_RS13070	COG0583	DNA-binding transcription factor activity
CN260_RS13090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CN260_RS13090	COG0519	Catalyzes the synthesis of GMP from XMP
CN260_RS13130	COG0596	Alpha beta hydrolase
CN260_RS13140	COG2205	protein histidine kinase activity
CN260_RS13160	COG0076	glutamate decarboxylase activity
CN260_RS13165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CN260_RS13170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CN260_RS13175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CN260_RS13180	COG1116	anion transmembrane transporter activity
CN260_RS13185	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CN260_RS13210	COG1609	Transcriptional regulator
CN260_RS13235	COG0402	S-adenosylhomocysteine deaminase activity
CN260_RS13240	COG1953	Uracil, thiamine, allantoin
CN260_RS13275	COG0406	alpha-ribazole phosphatase activity
CN260_RS13285	COG1335	isochorismatase
CN260_RS13325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CN260_RS13385	COG0765	amino acid transport
CN260_RS13395	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CN260_RS13410	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CN260_RS13415	COG0583	DNA-binding transcription factor activity
CN260_RS13425	COG1902	pentaerythritol trinitrate reductase activity
CN260_RS13465	COG1902	pentaerythritol trinitrate reductase activity
CN260_RS13470	COG4529	Protein conserved in bacteria
CN260_RS13475	COG0477	Major facilitator Superfamily
CN260_RS13500	COG2223	nitrite transmembrane transporter activity
CN260_RS13510	COG1609	Transcriptional regulator
CN260_RS13515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CN260_RS13525	COG3037	sugar-specific permease SgaT UlaA
CN260_RS13530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CN260_RS13540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CN260_RS13545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CN260_RS13545	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CN260_RS13545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CN260_RS13550	COG3039	Transposase
CN260_RS13565	COG1652	LysM domain
CN260_RS13595	COG0456	acetyltransferase
CN260_RS13595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CN260_RS13605	COG0667	Aldo Keto reductase
CN260_RS13610	COG0667	Aldo Keto reductase
CN260_RS13615	COG3386	PFAM SMP-30 Gluconolaconase
CN260_RS13620	COG0667	Aldo Keto reductase
CN260_RS13655	COG2801	Transposase and inactivated derivatives
CN260_RS13665	COG2801	Transposase and inactivated derivatives
CN260_RS13675	COG4977	sequence-specific DNA binding
CN260_RS13695	COG4977	sequence-specific DNA binding
CN260_RS13700	COG1349	DNA-binding transcription factor activity
CN260_RS13715	COG1349	DNA-binding transcription factor activity
CN260_RS13720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CN260_RS13725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CN260_RS13730	COG0738	Major facilitator superfamily
CN260_RS13775	COG1929	Belongs to the glycerate kinase type-1 family
CN260_RS13780	COG3835	regulator
CN260_RS13790	COG0583	DNA-binding transcription factor activity
CN260_RS13800	COG2186	Transcriptional regulator
CN260_RS13805	COG1263	PTS System
CN260_RS13805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CN260_RS13815	COG2814	Major facilitator Superfamily
CN260_RS13820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CN260_RS13820	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CN260_RS13830	COG2819	hydrolase of the alpha beta superfamily
CN260_RS13835	COG5001	Diguanylate cyclase
CN260_RS13835	COG3300	MHYT domain
CN260_RS13845	COG3039	Transposase
CN260_RS13880	COG3188	usher protein
CN260_RS13895	COG1649	PFAM Uncharacterised BCR, COG1649
CN260_RS13900	COG3550	peptidyl-serine autophosphorylation
CN260_RS13905	COG1396	sequence-specific DNA binding
CN260_RS13910	COG2351	hydroxyisourate hydrolase activity
CN260_RS13915	COG3195	allantoin biosynthetic process
CN260_RS13915	COG3648	Uricase
CN260_RS13920	COG2233	PERMEase
CN260_RS13950	COG2207	Transcriptional regulator
CN260_RS13965	COG4628	conserved protein (DUF2132)
CN260_RS13985	COG2011	ABC-type metal ion transport system permease component
CN260_RS13990	COG2070	2-Nitropropane dioxygenase
CN260_RS14000	COG0477	Major facilitator Superfamily
CN260_RS14075	COG2199	diguanylate cyclase activity
CN260_RS14090	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS14095	COG0583	DNA-binding transcription factor activity
CN260_RS14105	COG0039	L-malate dehydrogenase activity
CN260_RS14140	COG4977	sequence-specific DNA binding
CN260_RS14150	COG0697	spore germination
CN260_RS14155	COG2814	Major facilitator Superfamily
CN260_RS14170	COG1129	ABC transporter
CN260_RS14185	COG0683	leucine binding
CN260_RS14190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CN260_RS14225	COG2223	nitrite transmembrane transporter activity
CN260_RS14230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CN260_RS14245	COG1349	DNA-binding transcription factor activity
CN260_RS14250	COG2084	Dehydrogenase
CN260_RS14255	COG3395	kinase activity
CN260_RS14260	COG0235	Class ii aldolase
CN260_RS14265	COG3622	Belongs to the hyi family
CN260_RS14270	COG2610	gluconate transmembrane transporter activity
CN260_RS14290	COG2200	EAL domain
CN260_RS14295	COG1546	Belongs to the CinA family
CN260_RS14300	COG0071	Belongs to the small heat shock protein (HSP20) family
CN260_RS14310	COG2197	response regulator
CN260_RS14315	COG2135	peptidase activity
CN260_RS14320	COG2207	Transcriptional regulator
CN260_RS14335	COG4221	oxidoreductase activity
CN260_RS14340	COG1802	Transcriptional regulator
CN260_RS14345	COG0589	response to stress
CN260_RS14350	COG0246	Mannitol dehydrogenase
CN260_RS14355	COG2271	Major facilitator Superfamily
CN260_RS14370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CN260_RS14385	COG0243	molybdopterin cofactor binding
CN260_RS14390	COG0243	molybdopterin cofactor binding
CN260_RS14395	COG0437	4 iron, 4 sulfur cluster binding
CN260_RS14400	COG3302	dmso reductase anchor subunit
CN260_RS14415	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CN260_RS14420	COG1940	carbohydrate kinase activity
CN260_RS14425	COG0583	DNA-binding transcription factor activity
CN260_RS14430	COG2814	Major facilitator Superfamily
CN260_RS14435	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CN260_RS14445	COG3591	Belongs to the peptidase S1B family
CN260_RS14465	COG0628	permease
CN260_RS14495	COG0679	Auxin Efflux Carrier
CN260_RS14505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CN260_RS14545	COG3290	protein histidine kinase activity
CN260_RS14550	COG4565	transcriptional regulatory protein
CN260_RS14575	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CN260_RS14575	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CN260_RS14595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CN260_RS14600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CN260_RS14610	COG0183	Belongs to the thiolase family
CN260_RS14615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CN260_RS14625	COG1414	Transcriptional regulator
CN260_RS14630	COG2840	Smr protein MutS2
CN260_RS14635	COG0583	DNA-binding transcription factor activity
CN260_RS14645	COG1473	amidohydrolase
CN260_RS14650	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CN260_RS14665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CN260_RS14680	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CN260_RS14685	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CN260_RS14705	COG0531	amino acid
CN260_RS14715	COG3136	membrane protein required for alginate biosynthesis
CN260_RS14720	COG0745	RESPONSE REGULATOR receiver
CN260_RS14730	COG2205	protein histidine kinase activity
CN260_RS14740	COG0114	fumarate hydratase activity
CN260_RS14750	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CN260_RS14750	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CN260_RS14755	COG1482	cell wall glycoprotein biosynthetic process
CN260_RS14760	COG5339	Protein conserved in bacteria
CN260_RS14765	COG1609	Transcriptional regulator
CN260_RS14770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CN260_RS14770	COG1263	PTS System
CN260_RS14775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CN260_RS14800	COG2391	methyltransferase activity
CN260_RS14805	COG0425	Belongs to the sulfur carrier protein TusA family
CN260_RS14810	COG5562	phage envelope protein
CN260_RS14815	COG0401	homolog of Blt101
CN260_RS14820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CN260_RS14825	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS14830	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CN260_RS14835	COG0477	Major facilitator Superfamily
CN260_RS14840	COG1113	amino acid transport
CN260_RS14845	COG2988	succinylglutamate desuccinylase activity
CN260_RS14850	COG3724	N-succinylarginine dihydrolase activity
CN260_RS14855	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS14860	COG3138	arginine N-succinyltransferase
CN260_RS14865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CN260_RS14870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CN260_RS14875	COG0667	Aldo Keto reductase
CN260_RS14880	COG0583	DNA-binding transcription factor activity
CN260_RS14905	COG4122	O-methyltransferase activity
CN260_RS14910	COG1643	Atp-dependent helicase
CN260_RS14925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CN260_RS14930	COG3327	negative regulation of DNA-templated transcription, initiation
CN260_RS14935	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CN260_RS14940	COG0183	Belongs to the thiolase family
CN260_RS14945	COG2050	protein possibly involved in aromatic compounds catabolism
CN260_RS14950	COG1250	3-hydroxyacyl-CoA dehydrogenase
CN260_RS14955	COG1024	Enoyl-CoA hydratase
CN260_RS14960	COG1024	Enoyl-CoA hydratase
CN260_RS14965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CN260_RS14970	COG2151	metal-sulfur cluster biosynthetic enzyme
CN260_RS14975	COG3396	Phenylacetate-CoA oxygenase
CN260_RS14980	COG3460	Phenylacetate-CoA oxygenase
CN260_RS14985	COG3396	Phenylacetate-CoA oxygenase
CN260_RS14990	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS14990	COG2030	dehydratase
CN260_RS15035	COG2072	flavoprotein involved in K transport
CN260_RS15040	COG0583	DNA-binding transcription factor activity
CN260_RS15045	COG1126	abc transporter atp-binding protein
CN260_RS15055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CN260_RS15070	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS15075	COG2207	Transcriptional regulator
CN260_RS15080	COG3784	Protein of unknown function (DUF1318)
CN260_RS15090	COG2911	Protein conserved in bacteria
CN260_RS15095	COG0586	Pfam SNARE associated Golgi protein
CN260_RS15100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CN260_RS15105	COG3187	Heat shock protein
CN260_RS15110	COG3042	response to heat
CN260_RS15120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CN260_RS15120	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CN260_RS15120	COG1013	pyruvate-flavodoxin oxidoreductase activity
CN260_RS15120	COG0674	pyruvate-flavodoxin oxidoreductase activity
CN260_RS15125	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CN260_RS15135	COG0589	response to stress
CN260_RS15145	COG0513	Belongs to the DEAD box helicase family
CN260_RS15165	COG1349	DNA-binding transcription factor activity
CN260_RS15170	COG0673	inositol 2-dehydrogenase activity
CN260_RS15185	COG1113	amino acid transport
CN260_RS15190	COG1522	sequence-specific DNA binding
CN260_RS15200	COG1448	Aminotransferase
CN260_RS15205	COG2011	ABC-type metal ion transport system permease component
CN260_RS15220	COG0436	Aminotransferase
CN260_RS15225	COG0604	alcohol dehydrogenase
CN260_RS15250	COG0583	DNA-binding transcription factor activity
CN260_RS15270	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS15275	COG1309	transcriptional regulator
CN260_RS15280	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS15370	COG2885	chlorophyll binding
CN260_RS15395	COG0693	protein deglycase activity
CN260_RS15400	COG1078	dGTPase activity
CN260_RS15405	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS15410	COG0583	DNA-binding transcription factor activity
CN260_RS15430	COG0656	L-ascorbic acid biosynthetic process
CN260_RS15460	COG4166	transmembrane transport
CN260_RS15465	COG2866	Carboxypeptidase
CN260_RS15470	COG4948	Mandelate Racemase Muconate Lactonizing
CN260_RS15475	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CN260_RS15480	COG3180	Ammonia monooxygenase
CN260_RS15490	COG1486	melibiose metabolic process
CN260_RS15495	COG0583	DNA-binding transcription factor activity
CN260_RS15505	COG3106	COG3106 Predicted ATPase
CN260_RS15515	COG1983	PspC domain protein
CN260_RS15525	COG1842	Phage shock protein A
CN260_RS15530	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CN260_RS15555	COG0702	epimerase
CN260_RS15570	COG4171	peptide transport system, permease
CN260_RS15585	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CN260_RS15595	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CN260_RS15600	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CN260_RS15600	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CN260_RS15615	COG1349	DNA-binding transcription factor activity
CN260_RS15625	COG0023	Translation Initiation Factor
CN260_RS15635	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CN260_RS15640	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CN260_RS15645	COG0671	phosphoesterase, PA-phosphatase related
CN260_RS15655	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CN260_RS15685	COG0616	signal peptide processing
CN260_RS15695	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS15700	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CN260_RS15730	COG0583	DNA-binding transcription factor activity
CN260_RS15740	COG0009	L-threonylcarbamoyladenylate synthase
CN260_RS15750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CN260_RS15755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CN260_RS15755	COG0512	Glutamine amidotransferase of anthranilate synthase
CN260_RS15760	COG0135	phosphoribosylanthranilate isomerase activity
CN260_RS15760	COG0134	indole-3-glycerol-phosphate synthase activity
CN260_RS15795	COG4774	siderophore transport
CN260_RS15805	COG3047	cAMP biosynthetic process
CN260_RS15810	COG0727	PFAM Uncharacterised protein family (UPF0153)
CN260_RS15840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CN260_RS15845	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS15850	COG1988	membrane-bound metal-dependent
CN260_RS15855	COG1823	symporter activity
CN260_RS15865	COG0753	catalase activity
CN260_RS15875	COG1486	melibiose metabolic process
CN260_RS15880	COG2169	Transcriptional regulator
CN260_RS15880	COG1917	Cupin 2, conserved barrel domain protein
CN260_RS15885	COG1447	Phosphotransferase system cellobiose-specific component IIA
CN260_RS15890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CN260_RS15895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CN260_RS15900	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CN260_RS15910	COG0322	excinuclease ABC activity
CN260_RS15915	COG3678	ATP-independent chaperone mediated protein folding
CN260_RS15925	COG3724	N-succinylarginine dihydrolase activity
CN260_RS15935	COG3138	arginine N-succinyltransferase
CN260_RS15945	COG0708	Exodeoxyribonuclease III
CN260_RS15950	COG0398	Pfam SNARE associated Golgi protein
CN260_RS15955	COG0398	Pfam SNARE associated Golgi protein
CN260_RS15960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CN260_RS15965	COG4134	Bacterial extracellular solute-binding protein
CN260_RS15975	COG4136	ATPase activity
CN260_RS15980	COG2897	thiosulfate sulfurtransferase activity
CN260_RS15985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CN260_RS15990	COG0494	nUDIX hydrolase
CN260_RS15995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CN260_RS16000	COG0604	alcohol dehydrogenase
CN260_RS16000	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS16000	COG3321	synthase
CN260_RS16005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CN260_RS16010	COG0709	Synthesizes selenophosphate from selenide and ATP
CN260_RS16025	COG0778	Nitroreductase
CN260_RS16030	COG0616	signal peptide processing
CN260_RS16035	COG0252	asparaginase activity
CN260_RS16040	COG1335	isochorismatase
CN260_RS16055	COG3139	Protein of unknown function (DUF1315)
CN260_RS16075	COG0656	L-ascorbic acid biosynthetic process
CN260_RS16080	COG3713	MltA-interacting MipA family protein
CN260_RS16085	COG2766	serine protein kinase
CN260_RS16100	COG0386	Belongs to the glutathione peroxidase family
CN260_RS16120	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS16125	COG0583	DNA-binding transcription factor activity
CN260_RS16130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CN260_RS16135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CN260_RS16145	COG0859	PFAM glycosyl transferase family 9
CN260_RS16150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CN260_RS16160	COG2207	Transcriptional regulator
CN260_RS16165	COG2807	transmembrane transport
CN260_RS16170	COG0504	CTP synthase activity
CN260_RS16175	COG1683	Conserved Protein
CN260_RS16180	COG3189	MarR family transcriptional regulator
CN260_RS16185	COG3042	response to heat
CN260_RS16190	COG2199	diguanylate cyclase activity
CN260_RS16190	COG2203	Gaf domain
CN260_RS16210	COG3182	Iron-regulated membrane protein
CN260_RS16220	COG1560	Kdo2-lipid A biosynthetic process
CN260_RS16235	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CN260_RS16240	COG3706	GGDEF domain
CN260_RS16245	COG0583	DNA-binding transcription factor activity
CN260_RS16250	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CN260_RS16275	COG1294	oxidase, subunit
CN260_RS16280	COG1271	oxidase subunit
CN260_RS16285	COG3546	catalase activity
CN260_RS16290	COG3685	Protein conserved in bacteria
CN260_RS16295	COG3685	Protein conserved in bacteria
CN260_RS16300	COG3729	General stress protein
CN260_RS16305	COG1063	alcohol dehydrogenase
CN260_RS16310	COG3813	Protein conserved in bacteria
CN260_RS16330	COG0640	Transcriptional regulator
CN260_RS16335	COG0538	isocitrate dehydrogenase activity
CN260_RS16435	COG0616	signal peptide processing
CN260_RS16450	COG1802	Transcriptional regulator
CN260_RS16450	COG4626	Terminase
CN260_RS16480	COG3772	lysozyme
CN260_RS16495	COG1403	HNH endonuclease
CN260_RS16600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CN260_RS16610	COG0582	viral genome integration into host DNA
CN260_RS16625	COG0538	isocitrate dehydrogenase activity
CN260_RS16630	COG1187	pseudouridine synthase activity
CN260_RS16650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CN260_RS16670	COG2205	protein histidine kinase activity
CN260_RS16675	COG2850	peptidyl-arginine hydroxylation
CN260_RS16695	COG1177	transmembrane transport
CN260_RS16710	COG0318	PFAM AMP-dependent synthetase and ligase
CN260_RS16715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CN260_RS16720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CN260_RS16725	COG0698	ribose 5-phosphate isomerase
CN260_RS16740	COG3395	kinase activity
CN260_RS16755	COG2390	Transcriptional regulator
CN260_RS16765	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CN260_RS16775	COG4591	ABC-type transport system involved in lipoprotein release permease component
CN260_RS16785	COG4591	ABC-type transport system involved in lipoprotein release permease component
CN260_RS16795	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CN260_RS16800	COG1388	LysM domain
CN260_RS16800	COG1376	ErfK ybiS ycfS ynhG family protein
CN260_RS16810	COG1309	transcriptional regulator
CN260_RS16820	COG3134	Outer membrane lipoprotein
CN260_RS16825	COG1252	NADH dehydrogenase
CN260_RS16850	COG5633	Lipoprotein
CN260_RS16855	COG0537	adenosine 5'-monophosphoramidase activity
CN260_RS16865	COG0084	hydrolase, TatD family'
CN260_RS16870	COG0470	DNA polymerase III
CN260_RS16880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CN260_RS16885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CN260_RS16890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CN260_RS16905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CN260_RS16925	COG1399	metal-binding, possibly nucleic acid-binding protein
CN260_RS16945	COG1530	ribonuclease E activity
CN260_RS16950	COG0583	DNA-binding transcription factor activity
CN260_RS16955	COG2814	Major facilitator Superfamily
CN260_RS16975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CN260_RS17025	COG1560	Kdo2-lipid A biosynthetic process
CN260_RS17045	COG5645	(Lipo)protein
CN260_RS17085	COG3381	protein complex oligomerization
CN260_RS17115	COG1309	transcriptional regulator
CN260_RS17120	COG0583	DNA-binding transcription factor activity
CN260_RS17130	COG1335	isochorismatase
CN260_RS17145	COG1702	phosphate starvation-inducible protein PhoH
CN260_RS17165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CN260_RS17175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CN260_RS17195	COG1309	transcriptional regulator
CN260_RS17230	COG2233	PERMEase
CN260_RS17240	COG3729	General stress protein
CN260_RS17265	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS17280	COG0531	amino acid
CN260_RS17290	COG0174	glutamine synthetase
CN260_RS17295	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CN260_RS17300	COG1917	Cupin 2, conserved barrel domain protein
CN260_RS17300	COG1396	sequence-specific DNA binding
CN260_RS17305	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS17310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CN260_RS17315	COG0583	DNA-binding transcription factor activity
CN260_RS17320	COG0473	3-isopropylmalate dehydrogenase activity
CN260_RS17325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CN260_RS17330	COG4638	Rieske (2fe-2S)
CN260_RS17335	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS17340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CN260_RS17350	COG2200	EAL domain
CN260_RS17355	COG2200	EAL domain
CN260_RS17370	COG0670	Belongs to the BI1 family
CN260_RS17385	COG2207	Transcriptional regulator
CN260_RS17390	COG1881	PFAM PEBP family protein
CN260_RS17405	COG1832	CoA-binding protein
CN260_RS17415	COG0210	DNA helicase
CN260_RS17420	COG3304	Inner membrane component domain
CN260_RS17425	COG1289	transmembrane transporter activity
CN260_RS17430	COG3070	regulator of competence-specific genes
CN260_RS17455	COG1067	ATP-dependent peptidase activity
CN260_RS17465	COG3130	regulation of translation
CN260_RS17475	COG3009	Protein conserved in bacteria
CN260_RS17480	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CN260_RS17480	COG3008	intermembrane lipid transfer
CN260_RS17485	COG2995	paraquat-inducible protein a
CN260_RS17490	COG0488	(ABC) transporter
CN260_RS17500	COG3217	Mosc domain protein beta barrel domain protein
CN260_RS17500	COG0633	Ferredoxin
CN260_RS17515	COG0431	NADPH-dependent FMN reductase
CN260_RS17520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CN260_RS17525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CN260_RS17530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CN260_RS17540	COG0308	aminopeptidase N
CN260_RS17555	COG1473	amidohydrolase
CN260_RS17565	COG0814	amino acid
CN260_RS17575	COG1522	sequence-specific DNA binding
CN260_RS17585	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CN260_RS17590	COG1448	Aminotransferase
CN260_RS17595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CN260_RS17600	COG3108	Peptidase M15
CN260_RS17610	COG2989	Protein conserved in bacteria
CN260_RS17620	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CN260_RS17630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CN260_RS17635	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CN260_RS17640	COG3173	Aminoglycoside phosphotransferase
CN260_RS17655	COG3214	Protein conserved in bacteria
CN260_RS17670	COG0658	competence protein
CN260_RS17670	COG2333	competence protein COMEC
CN260_RS17680	COG0539	negative regulation of cytoplasmic translation
CN260_RS17700	COG2323	membrane
CN260_RS17705	COG1944	ATP diphosphatase activity
CN260_RS17710	COG2116	formate transmembrane transporter activity
CN260_RS17715	COG1882	Formate acetyltransferase
CN260_RS17720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CN260_RS17725	COG0477	Major facilitator Superfamily
CN260_RS17735	COG3302	dmso reductase anchor subunit
CN260_RS17740	COG0437	4 iron, 4 sulfur cluster binding
CN260_RS17745	COG0243	molybdopterin cofactor binding
CN260_RS17755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CN260_RS17765	COG1674	ftsk spoiiie
CN260_RS17765	COG1178	ABC-type Fe3 transport system permease component
CN260_RS17775	COG0492	ferredoxin-NADP+ reductase activity
CN260_RS17780	COG4988	ABC transporter
CN260_RS17785	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CN260_RS17800	COG0542	response to heat
CN260_RS17810	COG1278	Cold shock
CN260_RS17825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CN260_RS17830	COG3593	DNA synthesis involved in DNA repair
CN260_RS17840	COG2431	L-lysine efflux transmembrane transporter activity
CN260_RS17850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CN260_RS17865	COG0028	Belongs to the TPP enzyme family
CN260_RS17870	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CN260_RS17875	COG0702	epimerase
CN260_RS17880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CN260_RS17885	COG3023	N-Acetylmuramoyl-L-alanine amidase
CN260_RS17890	COG3706	GGDEF domain
CN260_RS17890	COG5001	Diguanylate cyclase
CN260_RS17890	COG4251	negative regulation of phosphorylation
CN260_RS17890	COG2203	Gaf domain
CN260_RS17905	COG1126	abc transporter atp-binding protein
CN260_RS17910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CN260_RS17915	COG4215	(ABC) transporter
CN260_RS17920	COG4160	amino acid transport
CN260_RS17925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CN260_RS17930	COG5002	protein histidine kinase activity
CN260_RS17935	COG0745	RESPONSE REGULATOR receiver
CN260_RS17950	COG1177	transmembrane transport
CN260_RS17955	COG1176	ABC-type spermidine putrescine transport system, permease component I
CN260_RS17960	COG3842	ATPase activity
CN260_RS17965	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CN260_RS17980	COG0778	Nitroreductase
CN260_RS18005	COG3226	Transcriptional regulator
CN260_RS18010	COG0738	Major facilitator superfamily
CN260_RS18015	COG0561	phosphatase activity
CN260_RS18020	COG2814	Major facilitator Superfamily
CN260_RS18030	COG0671	phosphoesterase, PA-phosphatase related
CN260_RS18035	COG1349	DNA-binding transcription factor activity
CN260_RS18040	COG1686	Belongs to the peptidase S11 family
CN260_RS18050	COG0625	glutathione transferase activity
CN260_RS18055	COG2133	pyrroloquinoline quinone binding
CN260_RS18065	COG2223	nitrite transmembrane transporter activity
CN260_RS18090	COG0747	negative chemotaxis
CN260_RS18100	COG1446	asparaginase
CN260_RS18105	COG0303	'Molybdopterin
CN260_RS18110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CN260_RS18115	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CN260_RS18120	COG1882	Formate acetyltransferase
CN260_RS18125	COG0561	phosphatase activity
CN260_RS18135	COG1609	Transcriptional regulator
CN260_RS18140	COG2271	Major facilitator Superfamily
CN260_RS18150	COG0488	(ABC) transporter
CN260_RS18155	COG2365	Tyrosine phosphatase family
CN260_RS18160	COG1376	ErfK ybiS ycfS ynhG family protein
CN260_RS18165	COG2188	Transcriptional regulator
CN260_RS18170	COG2723	6-phospho-beta-galactosidase activity
CN260_RS18175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CN260_RS18190	COG2194	sulfuric ester hydrolase activity
CN260_RS18195	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CN260_RS18210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CN260_RS18215	COG0765	amino acid transport
CN260_RS18220	COG1126	abc transporter atp-binding protein
CN260_RS18225	COG0668	transmembrane transport
CN260_RS18235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CN260_RS18245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CN260_RS18255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CN260_RS18260	COG1199	ATP-dependent helicase activity
CN260_RS18265	COG0513	Belongs to the DEAD box helicase family
CN260_RS18270	COG3958	Transketolase
CN260_RS18275	COG3959	Transketolase, thiamine diphosphate binding domain
CN260_RS18280	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS18285	COG2271	Major facilitator Superfamily
CN260_RS18290	COG0583	DNA-binding transcription factor activity
CN260_RS18295	COG1309	transcriptional regulator
CN260_RS18300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CN260_RS18305	COG1131	(ABC) transporter
CN260_RS18310	COG0842	Transport permease protein
CN260_RS18315	COG0842	Transport permease protein
CN260_RS18330	COG3568	Endonuclease Exonuclease Phosphatase
CN260_RS18335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CN260_RS18340	COG0392	lysyltransferase activity
CN260_RS18345	COG0670	Belongs to the BI1 family
CN260_RS18350	COG0314	molybdopterin synthase activity
CN260_RS18355	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CN260_RS18365	COG0521	Mo-molybdopterin cofactor biosynthetic process
CN260_RS18390	COG0745	RESPONSE REGULATOR receiver
CN260_RS18395	COG0642	Histidine kinase
CN260_RS18430	COG2226	methyltransferase
CN260_RS18450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CN260_RS18455	COG1881	PFAM PEBP family protein
CN260_RS18495	COG4677	pectinesterase activity
CN260_RS18505	COG0589	response to stress
CN260_RS18510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CN260_RS18540	COG0789	Transcriptional regulator
CN260_RS18545	COG2200	EAL domain
CN260_RS18570	COG0561	phosphatase activity
CN260_RS18580	COG4149	molybdate abc transporter
CN260_RS18585	COG0725	ABC transporter, periplasmic molybdate-binding protein
CN260_RS18595	COG3585	molybdate ion transport
CN260_RS18595	COG2005	Transcriptional regulator
CN260_RS18600	COG1119	ATPase activity
CN260_RS18610	COG1085	galactose-1-phosphate uridylyltransferase
CN260_RS18620	COG2017	converts alpha-aldose to the beta-anomer
CN260_RS18655	COG0471	metal ion transport
CN260_RS18655	COG0490	domain, Protein
CN260_RS18660	COG0583	DNA-binding transcription factor activity
CN260_RS18675	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CN260_RS18675	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CN260_RS18680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CN260_RS18695	COG3201	nicotinamide mononucleotide transporter
CN260_RS18700	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CN260_RS18745	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CN260_RS18750	COG2885	chlorophyll binding
CN260_RS18760	COG3064	Membrane
CN260_RS18765	COG0848	biopolymer transport protein
CN260_RS18770	COG0811	peptide transport
CN260_RS18775	COG0824	Thioesterase
CN260_RS18780	COG3790	cyd operon protein YbgE
CN260_RS18785	COG4890	Cyd operon protein YbgT
CN260_RS18790	COG1294	oxidase, subunit
CN260_RS18795	COG1271	oxidase subunit
CN260_RS18805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CN260_RS18815	COG0508	dehydrogenase complex catalyzes the overall conversion of
CN260_RS18820	COG0567	Dehydrogenase, E1 component
CN260_RS18825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CN260_RS18830	COG1053	succinate dehydrogenase
CN260_RS18835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CN260_RS18840	COG2009	succinate dehydrogenase
CN260_RS18885	COG1984	allophanate hydrolase subunit 2
CN260_RS18890	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CN260_RS18905	COG0415	Belongs to the DNA photolyase family
CN260_RS18935	COG2205	protein histidine kinase activity
CN260_RS18940	COG0745	RESPONSE REGULATOR receiver
CN260_RS18950	COG0033	Phosphoglucomutase
CN260_RS18960	COG0596	Alpha beta hydrolase
CN260_RS18975	COG0735	belongs to the Fur family
CN260_RS19020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CN260_RS19025	COG1846	Transcriptional regulator
CN260_RS19025	COG1940	carbohydrate kinase activity
CN260_RS19030	COG0647	UMP catabolic process
CN260_RS19035	COG0367	asparagine synthase
CN260_RS19080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CN260_RS19090	COG1702	phosphate starvation-inducible protein PhoH
CN260_RS19100	COG4535	Mg2 and Co2 transporter CorC
CN260_RS19115	COG0765	amino acid transport
CN260_RS19120	COG0765	amino acid transport
CN260_RS19125	COG1126	abc transporter atp-binding protein
CN260_RS19140	COG2888	peptidyl-tyrosine sulfation
CN260_RS19155	COG1466	dna polymerase III delta subunit
CN260_RS19175	COG0799	negative regulation of ribosome biogenesis
CN260_RS19185	COG0768	penicillin binding
CN260_RS19190	COG0772	Belongs to the SEDS family
CN260_RS19195	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CN260_RS19200	COG1686	Belongs to the peptidase S11 family
CN260_RS19215	COG0583	DNA-binding transcription factor activity
CN260_RS19230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CN260_RS19250	COG3069	C4-dicarboxylate transmembrane transporter activity
CN260_RS19255	COG3719	Belongs to the RNase T2 family
CN260_RS19260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CN260_RS19280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CN260_RS19285	COG0583	DNA-binding transcription factor activity
CN260_RS19290	COG3969	phosphoadenosine phosphosulfate
CN260_RS19295	COG1475	DNA binding
CN260_RS19300	COG0436	Aminotransferase
CN260_RS19325	COG1129	ABC transporter
CN260_RS19330	COG1172	Belongs to the binding-protein-dependent transport system permease family
CN260_RS19335	COG1172	Belongs to the binding-protein-dependent transport system permease family
CN260_RS19345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CN260_RS19360	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CN260_RS19370	COG0402	S-adenosylhomocysteine deaminase activity
CN260_RS19380	COG0483	inositol monophosphate 1-phosphatase activity
CN260_RS19385	COG2271	Major facilitator Superfamily
CN260_RS19415	COG1172	Belongs to the binding-protein-dependent transport system permease family
CN260_RS19420	COG1129	ABC transporter
CN260_RS19425	COG0371	Dehydrogenase
CN260_RS19445	COG2879	small protein
CN260_RS19450	COG1966	Carbon starvation protein
CN260_RS19460	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS19465	COG1535	isochorismatase
CN260_RS19465	COG3433	isochorismatase activity
CN260_RS19470	COG1021	2,3-dihydroxybenzoate-AMP ligase
CN260_RS19475	COG1169	isochorismate synthase
CN260_RS19480	COG4592	Periplasmic binding protein
CN260_RS19490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CN260_RS19495	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CN260_RS19500	COG1120	ATPase activity
CN260_RS19505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CN260_RS19505	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CN260_RS19510	COG3251	PFAM MbtH domain protein
CN260_RS19515	COG2382	esterase
CN260_RS19520	COG4771	TonB-dependent receptor
CN260_RS19525	COG2977	Belongs to the P-Pant transferase superfamily
CN260_RS19530	COG3958	Transketolase
CN260_RS19535	COG3959	Transketolase, thiamine diphosphate binding domain
CN260_RS19545	COG2390	Transcriptional regulator
CN260_RS19550	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CN260_RS19555	COG1879	ABC-type sugar transport system periplasmic component
CN260_RS19565	COG1129	ABC transporter
CN260_RS19570	COG1172	Belongs to the binding-protein-dependent transport system permease family
CN260_RS19580	COG1028	Short-chain dehydrogenase reductase Sdr
CN260_RS19590	COG0583	DNA-binding transcription factor activity
CN260_RS19595	COG0668	transmembrane transport
CN260_RS19605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CN260_RS19635	COG0747	negative chemotaxis
CN260_RS19640	COG0601	transmembrane transport
CN260_RS19645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CN260_RS19650	COG0444	Belongs to the ABC transporter superfamily
CN260_RS19655	COG4608	Belongs to the ABC transporter superfamily
CN260_RS19665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CN260_RS19670	COG4221	oxidoreductase activity
CN260_RS19680	COG4215	(ABC) transporter
CN260_RS19685	COG0765	amino acid transport
CN260_RS19690	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CN260_RS19730	COG4608	Belongs to the ABC transporter superfamily
CN260_RS19735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CN260_RS19745	COG4166	transmembrane transport
CN260_RS19755	COG3698	Phosphodiester glycosidase
CN260_RS19800	COG2315	Protein conserved in bacteria
CN260_RS19805	COG0778	Nitroreductase
CN260_RS19815	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CN260_RS19825	COG3716	PTS system mannose fructose sorbose family IID component
CN260_RS19830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CN260_RS19835	COG2222	sugar isomerase
CN260_RS19840	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CN260_RS19840	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CN260_RS19860	COG0477	Major facilitator Superfamily
CN260_RS19865	COG0668	transmembrane transport
CN260_RS19870	COG1609	Transcriptional regulator
CN260_RS19880	COG0673	inositol 2-dehydrogenase activity
CN260_RS19890	COG2211	Major facilitator Superfamily
CN260_RS19895	COG1113	amino acid transport
CN260_RS19910	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS19915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CN260_RS19925	COG0531	amino acid
CN260_RS19940	COG4680	protein conserved in bacteria
CN260_RS19985	COG0667	Aldo Keto reductase
CN260_RS19990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CN260_RS19995	COG1473	amidohydrolase
CN260_RS20015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CN260_RS20020	COG1120	ATPase activity
CN260_RS20025	COG1566	PFAM secretion protein HlyD family protein
CN260_RS20070	COG4211	Belongs to the binding-protein-dependent transport system permease family
CN260_RS20075	COG1129	ABC transporter
CN260_RS20090	COG0673	inositol 2-dehydrogenase activity
CN260_RS20125	COG3104	oligopeptide transport
CN260_RS20130	COG1982	Orn Lys Arg decarboxylase major
CN260_RS20135	COG0531	amino acid
CN260_RS20140	COG3710	Transcriptional regulator
CN260_RS20150	COG1560	Kdo2-lipid A biosynthetic process
CN260_RS20165	COG3188	usher protein
CN260_RS20170	COG3121	Chaperone
CN260_RS20175	COG3539	Fimbrial protein
CN260_RS20230	COG2501	S4 domain
CN260_RS20240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CN260_RS20260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CN260_RS20265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CN260_RS20280	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CN260_RS20285	COG4181	ATPase activity
CN260_RS20290	COG2755	lipolytic protein G-D-S-L family
CN260_RS20295	COG0300	oxidoreductase activity
CN260_RS20300	COG3118	belongs to the thioredoxin family
CN260_RS20310	COG0390	transport system, permease component
CN260_RS20315	COG4619	ABC transporter
CN260_RS20320	COG0330	HflC and HflK could
CN260_RS20325	COG1585	Membrane protein implicated in regulation of membrane protease activity
CN260_RS20340	COG3735	TraB family
CN260_RS20345	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CN260_RS20355	COG2223	nitrite transmembrane transporter activity
CN260_RS20360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CN260_RS20360	COG4651	solute:proton antiporter activity
CN260_RS20365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CN260_RS20410	COG2832	Protein of unknown function (DUF454)
CN260_RS20415	COG3923	Primosomal replication protein n
CN260_RS20430	COG1196	nuclear chromosome segregation
CN260_RS20430	COG3264	Mechanosensitive ion channel
CN260_RS20435	COG1309	transcriptional regulator
CN260_RS20440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CN260_RS20445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CN260_RS20460	COG0110	maltose O-acetyltransferase activity
CN260_RS20505	COG1874	Beta-galactosidase
CN260_RS20510	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CN260_RS20515	COG3833	ABC-type maltose transport systems, permease component
CN260_RS20520	COG1175	transmembrane transport
CN260_RS20525	COG2182	Extracellular solute-binding protein
CN260_RS20535	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CN260_RS20550	COG2364	Membrane
CN260_RS20610	COG0582	viral genome integration into host DNA
CN260_RS20625	COG3695	enzyme binding
CN260_RS20630	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CN260_RS20635	COG1946	Acyl-CoA thioesterase
CN260_RS20640	COG0004	ammonium transporteR
CN260_RS20645	COG0347	Belongs to the P(II) protein family
CN260_RS20650	COG1132	(ABC) transporter
CN260_RS20655	COG1132	(ABC) transporter
CN260_RS20660	COG1522	sequence-specific DNA binding
CN260_RS20675	COG4533	DNA binding
CN260_RS20685	COG0824	Thioesterase
CN260_RS20690	COG1555	photosystem II stabilization
CN260_RS20695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CN260_RS20700	COG0776	regulation of translation
CN260_RS20705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CN260_RS20735	COG0271	Belongs to the BolA IbaG family
CN260_RS20740	COG3056	Lipoprotein
CN260_RS20745	COG2223	nitrite transmembrane transporter activity
CN260_RS20750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CN260_RS20755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CN260_RS20760	COG1845	cytochrome c oxidase, subunit III
CN260_RS20765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CN260_RS20780	COG1414	Transcriptional regulator
CN260_RS20790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CN260_RS20795	COG1053	succinate dehydrogenase
CN260_RS20805	COG1053	succinate dehydrogenase
CN260_RS20820	COG0673	inositol 2-dehydrogenase activity
CN260_RS20825	COG2814	Major facilitator Superfamily
CN260_RS20835	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CN260_RS20840	COG0693	protein deglycase activity
CN260_RS20860	COG0142	geranyltranstransferase activity
CN260_RS20870	COG0667	Aldo Keto reductase
CN260_RS20875	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CN260_RS20895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CN260_RS20895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CN260_RS20905	COG4238	major outer membrane lipoprotein
CN260_RS20925	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CN260_RS20930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CN260_RS20935	COG1862	Preprotein translocase
CN260_RS20955	COG0450	alkyl hydroperoxide reductase
CN260_RS20960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CN260_RS20975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CN260_RS20985	COG1228	amidohydrolase
CN260_RS20995	COG1335	isochorismatase
CN260_RS21000	COG0583	DNA-binding transcription factor activity
CN260_RS21005	COG0366	Alpha amylase catalytic
CN260_RS21030	COG0420	3'-5' exonuclease activity
CN260_RS21035	COG0419	ATPase involved in DNA repair
CN260_RS21040	COG1940	carbohydrate kinase activity
CN260_RS21055	COG4126	flavin adenine dinucleotide binding
CN260_RS21065	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CN260_RS21070	COG3416	Protein conserved in bacteria
CN260_RS21080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CN260_RS21090	COG1785	Belongs to the alkaline phosphatase family
CN260_RS21130	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CN260_RS21135	COG1335	isochorismatase
CN260_RS21140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CN260_RS21145	COG0113	porphobilinogen synthase activity
CN260_RS21150	COG1943	Transposase
CN260_RS21160	COG2175	clavaminate synthase activity
CN260_RS21165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CN260_RS21170	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CN260_RS21175	COG4521	taurine ABC transporter
CN260_RS21180	COG2040	homocysteine
CN260_RS21185	COG0833	amino acid
CN260_RS21195	COG4303	Ethanolamine ammonia lyase large subunit
CN260_RS21200	COG4302	ethanolamine ammonia-lyase activity
CN260_RS21235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CN260_RS21240	COG1126	abc transporter atp-binding protein
CN260_RS21245	COG4597	amino acid ABC transporter
CN260_RS21250	COG0765	amino acid transport
CN260_RS21265	COG3188	usher protein
CN260_RS21290	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CN260_RS21300	COG3639	organic phosphonate transmembrane transporter activity
CN260_RS21320	COG0791	NLP P60 protein
CN260_RS21345	COG0582	viral genome integration into host DNA
CN260_RS21380	COG3121	Chaperone
CN260_RS21385	COG3188	usher protein
CN260_RS21400	COG0745	RESPONSE REGULATOR receiver
CN260_RS21420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CN260_RS21425	COG0022	dehydrogenase e1 component
CN260_RS21430	COG0508	dehydrogenase complex catalyzes the overall conversion of
CN260_RS21435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CN260_RS21445	COG0625	glutathione transferase activity
CN260_RS21450	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CN260_RS21470	COG0579	oxidoreductase
CN260_RS21475	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS21480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CN260_RS21485	COG1113	amino acid transport
CN260_RS21490	COG1802	Transcriptional regulator
CN260_RS21510	COG2195	Cleaves the N-terminal amino acid of tripeptides
CN260_RS21515	COG0454	-acetyltransferase
CN260_RS21530	COG2991	Protein conserved in bacteria
CN260_RS21545	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CN260_RS21550	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CN260_RS21570	COG3034	peptidoglycan biosynthetic process
CN260_RS21575	COG0121	glutamine amidotransferase
CN260_RS21585	COG1960	acyl-CoA dehydrogenase activity
CN260_RS21590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CN260_RS21600	COG0583	DNA-binding transcription factor activity
CN260_RS21615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CN260_RS21625	COG2226	methyltransferase
CN260_RS21635	COG0741	lytic transglycosylase activity
CN260_RS21635	COG1388	LysM domain
CN260_RS21640	COG2226	methyltransferase
CN260_RS21650	COG2814	Major facilitator Superfamily
CN260_RS21655	COG0583	DNA-binding transcription factor activity
CN260_RS21660	COG0656	L-ascorbic acid biosynthetic process
CN260_RS21700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CN260_RS21710	COG2011	ABC-type metal ion transport system permease component
CN260_RS21715	COG1464	Belongs to the NlpA lipoprotein family
CN260_RS21725	COG1720	tRNA m6t6A37 methyltransferase activity
CN260_RS21735	COG0791	NLP P60 protein
CN260_RS21740	COG3015	lipoprotein NlpE involved in copper resistance
CN260_RS21745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CN260_RS21760	COG4568	rho-dependent transcription termination
CN260_RS21770	COG0346	lactoylglutathione lyase activity
CN260_RS21775	COG1982	Orn Lys Arg decarboxylase major
CN260_RS21785	COG0587	DNA-directed DNA polymerase activity
CN260_RS21815	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CN260_RS21825	COG0750	zinc metalloprotease
CN260_RS21830	COG0575	Belongs to the CDS family
CN260_RS21845	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CN260_RS21870	COG0024	Methionine aminopeptidase
CN260_RS21875	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CN260_RS21890	COG3835	regulator
CN260_RS21895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CN260_RS21915	COG2860	membrane
CN260_RS21935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CN260_RS21940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CN260_RS21945	COG1120	ATPase activity
CN260_RS21950	COG4774	siderophore transport
CN260_RS21955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CN260_RS22045	COG1643	Atp-dependent helicase
CN260_RS22050	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CN260_RS22070	COG0617	tRNA 3'-terminal CCA addition
CN260_RS22075	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CN260_RS22095	COG0726	polysaccharide deacetylase
CN260_RS22100	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CN260_RS22105	COG0842	Transport permease protein
CN260_RS22110	COG1131	(ABC) transporter
CN260_RS22115	COG0288	reversible hydration of carbon dioxide
CN260_RS22125	COG4993	Dehydrogenase
CN260_RS22130	COG2132	Multicopper oxidase
CN260_RS22175	COG3064	Membrane
CN260_RS22190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CN260_RS22195	COG0508	dehydrogenase complex catalyzes the overall conversion of
CN260_RS22200	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CN260_RS22205	COG2186	Transcriptional regulator
CN260_RS22210	COG1113	amino acid transport
CN260_RS22215	COG2211	Major facilitator Superfamily
CN260_RS22220	COG3940	Belongs to the glycosyl hydrolase 43 family
CN260_RS22225	COG3725	Membrane protein required for beta-lactamase induction
CN260_RS22230	COG3023	N-Acetylmuramoyl-L-alanine amidase
CN260_RS22240	COG4969	Belongs to the N-Me-Phe pilin family
CN260_RS22245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CN260_RS22250	COG1459	type II secretion system
CN260_RS22275	COG0494	nUDIX hydrolase
CN260_RS22295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CN260_RS22300	COG0849	cell division
CN260_RS22325	COG0772	Belongs to the SEDS family
CN260_RS22340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CN260_RS22345	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CN260_RS22350	COG0768	penicillin binding
CN260_RS22375	COG1609	Transcriptional regulator
CN260_RS22385	COG0028	Belongs to the TPP enzyme family
CN260_RS22435	COG0738	Major facilitator superfamily
CN260_RS22445	COG0583	DNA-binding transcription factor activity
CN260_RS22450	COG2271	Major facilitator Superfamily
CN260_RS22455	COG2814	Major facilitator Superfamily
CN260_RS22475	COG1178	ABC-type Fe3 transport system permease component
CN260_RS22485	COG0586	Pfam SNARE associated Golgi protein
CN260_RS22505	COG0235	Class ii aldolase
CN260_RS22510	COG0417	DNA replication proofreading
CN260_RS22520	COG0564	pseudouridine synthase activity
CN260_RS22535	COG3493	citrate carrier protein
CN260_RS22550	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CN260_RS22555	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CN260_RS22565	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CN260_RS22615	COG0505	Belongs to the CarA family
CN260_RS22680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CN260_RS22705	COG1047	Peptidyl-prolyl cis-trans
CN260_RS22720	COG0196	riboflavin kinase activity
CN260_RS22735	COG0583	DNA-binding transcription factor activity
CN260_RS22760	COG4735	regulation of single-species biofilm formation
CN260_RS22765	COG1584	GPR1 FUN34 yaaH family protein
CN260_RS22770	COG0477	Major facilitator Superfamily
CN260_RS22775	COG0521	Mo-molybdopterin cofactor biosynthetic process
CN260_RS22780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CN260_RS22785	COG1115	amino acid carrier protein
CN260_RS22800	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CN260_RS22810	COG0527	aspartate kinase activity
CN260_RS22810	COG0460	homoserine dehydrogenase
CN260_RS22820	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CN260_RS22835	COG0745	RESPONSE REGULATOR receiver
CN260_RS22840	COG4452	Inner membrane protein CreD
CN260_RS22845	COG2205	protein histidine kinase activity
CN260_RS22850	COG0745	RESPONSE REGULATOR receiver
CN260_RS22855	COG3045	CreA protein
CN260_RS22860	COG3708	Transcriptional regulator
CN260_RS22860	COG2207	Transcriptional regulator
CN260_RS22880	COG0741	lytic transglycosylase activity
CN260_RS22890	COG0488	(ABC) transporter
CN260_RS22900	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CN260_RS22905	COG0560	Phosphoserine phosphatase
CN260_RS22915	COG3726	membrane protein affecting hemolysin expression
CN260_RS22945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CN260_RS22950	COG0084	hydrolase, TatD family'
CN260_RS22955	COG4667	esterase of the alpha-beta hydrolase superfamily
CN260_RS22965	COG2823	Periplasmic or secreted lipoprotein
CN260_RS22975	COG1011	Hydrolase
CN260_RS22980	COG0456	acetyltransferase
CN260_RS22985	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CN260_RS23015	COG3706	GGDEF domain
CN260_RS23020	COG4114	ferric iron reductase
CN260_RS23025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CN260_RS23025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CN260_RS23030	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CN260_RS23035	COG2197	response regulator
CN260_RS23040	COG2197	response regulator
CN260_RS23060	COG2966	Psort location CytoplasmicMembrane, score
CN260_RS23075	COG1484	DNA-dependent DNA replication
CN260_RS23090	COG5464	transposase or invertase
CN260_RS23100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CN260_RS23105	COG3716	PTS system mannose fructose sorbose family IID component
CN260_RS23110	COG3715	PTS system
CN260_RS23125	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CN260_RS23125	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CN260_RS23130	COG1214	PFAM Peptidase M22, glycoprotease
CN260_RS23130	COG0456	acetyltransferase
CN260_RS23140	COG1737	Transcriptional regulator
CN260_RS23145	COG0800	Aldolase
CN260_RS23150	COG3734	2-keto-3-deoxy-galactonokinase
CN260_RS23165	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CN260_RS23195	COG1846	Transcriptional regulator
CN260_RS23200	COG0179	Fumarylacetoacetate (FAA) hydrolase
CN260_RS23210	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS23215	COG3384	dioxygenase
CN260_RS23225	COG3971	2-oxopent-4-enoate hydratase activity
CN260_RS23245	COG2368	4-hydroxyphenylacetate
CN260_RS23250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CN260_RS23265	COG1966	Carbon starvation protein
CN260_RS23270	COG2879	small protein
CN260_RS23275	COG0523	cobalamin synthesis protein
CN260_RS23285	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS23290	COG5464	transposase or invertase
CN260_RS23295	COG2207	Transcriptional regulator
CN260_RS23295	COG1917	Cupin 2, conserved barrel domain protein
CN260_RS23305	COG2733	membrane
CN260_RS23320	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CN260_RS23325	COG1924	4 iron, 4 sulfur cluster binding
CN260_RS23340	COG1566	PFAM secretion protein HlyD family protein
CN260_RS23350	COG5457	Domain of unknown function (DUF1127)
CN260_RS23355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CN260_RS23375	COG0732	type I restriction modification DNA specificity domain
CN260_RS23390	COG0583	DNA-binding transcription factor activity
CN260_RS23395	COG2249	NAD(P)H dehydrogenase (quinone) activity
CN260_RS23405	COG1172	Belongs to the binding-protein-dependent transport system permease family
CN260_RS23410	COG1129	ABC transporter
CN260_RS23415	COG1879	ABC-type sugar transport system periplasmic component
CN260_RS23425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CN260_RS23430	COG1129	ABC transporter
CN260_RS23430	COG0842	Transport permease protein
CN260_RS23435	COG0842	Transport permease protein
CN260_RS23475	COG2850	peptidyl-arginine hydroxylation
CN260_RS23490	COG5002	protein histidine kinase activity
CN260_RS23495	COG0745	RESPONSE REGULATOR receiver
CN260_RS23500	COG1538	Outer membrane efflux protein
CN260_RS23505	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CN260_RS23510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CN260_RS23515	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CN260_RS23525	COG3040	lipid binding
CN260_RS23530	COG0789	Transcriptional regulator
CN260_RS23540	COG0300	oxidoreductase activity
CN260_RS23555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CN260_RS23575	COG3272	Protein of unknown function (DUF1722)
CN260_RS23580	COG4580	involved in the transport of maltose and maltodextrins
CN260_RS23585	COG2115	Belongs to the xylose isomerase family
CN260_RS23590	COG2211	Major facilitator Superfamily
CN260_RS23595	COG3507	Belongs to the glycosyl hydrolase 43 family
CN260_RS23805	COG0288	reversible hydration of carbon dioxide
CN260_RS23810	COG0659	secondary active sulfate transmembrane transporter activity
CN260_RS23815	COG1064	alcohol dehydrogenase
CN260_RS23820	COG1175	transmembrane transport
CN260_RS23825	COG0395	ABC-type sugar transport system, permease component
CN260_RS23830	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CN260_RS23835	COG3842	ATPase activity
CN260_RS23850	COG1082	Xylose isomerase domain protein TIM barrel
CN260_RS23860	COG3962	Belongs to the TPP enzyme family
CN260_RS23865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CN260_RS23870	COG0837	glucose binding
CN260_RS23870	COG1737	Transcriptional regulator
CN260_RS23880	COG3718	enzyme involved in inositol metabolism
CN260_RS23895	COG0433	COG0433 Predicted ATPase
CN260_RS23900	COG0795	lipopolysaccharide-transporting ATPase activity
CN260_RS23905	COG0795	lipopolysaccharide-transporting ATPase activity
CN260_RS23920	COG2927	DNA polymerase III (CHI subunit)
CN260_RS23925	COG0525	valine-tRNA ligase activity
CN260_RS23950	COG2731	YhcH YjgK YiaL family protein
CN260_RS23995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CN260_RS23995	COG1263	PTS System
CN260_RS24000	COG0366	Alpha amylase catalytic
CN260_RS24005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CN260_RS24010	COG1486	melibiose metabolic process
CN260_RS24030	COG0602	queuosine metabolic process
CN260_RS24035	COG2026	Addiction module toxin, RelE StbE family
CN260_RS24040	COG3077	Addiction module antitoxin, RelB DinJ family
CN260_RS24045	COG3711	transcriptional antiterminator
CN260_RS24045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CN260_RS24050	COG2706	6-phosphogluconolactonase activity
CN260_RS24065	COG3964	amidohydrolase
CN260_RS24100	COG0312	modulator of DNA gyrase
CN260_RS24120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CN260_RS24130	COG1172	Belongs to the binding-protein-dependent transport system permease family
CN260_RS24135	COG1172	Belongs to the binding-protein-dependent transport system permease family
CN260_RS24140	COG1129	ABC transporter
CN260_RS24145	COG1879	ABC-type sugar transport system periplasmic component
CN260_RS24165	COG2105	PFAM AIG2 family protein
CN260_RS24170	COG2911	Protein conserved in bacteria
CN260_RS24175	COG0729	surface antigen
CN260_RS24185	COG1253	flavin adenine dinucleotide binding
CN260_RS24200	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CN260_RS24215	COG1733	regulation of RNA biosynthetic process
CN260_RS24220	COG0702	epimerase
CN260_RS24230	COG0697	spore germination
CN260_RS24240	COG1113	amino acid transport
CN260_RS24245	COG0545	Peptidyl-prolyl cis-trans isomerase
CN260_RS24250	COG3061	Opacity-associated protein A
CN260_RS24260	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CN260_RS24265	COG2965	DNA replication, synthesis of RNA primer
CN260_RS24325	COG1073	alpha beta
CN260_RS24330	COG3650	response to hydrogen peroxide
CN260_RS24340	COG1960	acyl-CoA dehydrogenase activity
CN260_RS24345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CN260_RS24350	COG0557	exoribonuclease II activity
CN260_RS24365	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CN260_RS24375	COG0330	HflC and HflK could
CN260_RS24380	COG0330	HflC and HflK could
CN260_RS24385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CN260_RS24405	COG0860	N-Acetylmuramoyl-L-alanine amidase
CN260_RS24410	COG0802	atpase or kinase
CN260_RS24415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CN260_RS24415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CN260_RS24420	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CN260_RS24445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CN260_RS24470	COG1511	domain protein
CN260_RS24470	COG3264	Mechanosensitive ion channel
CN260_RS24485	COG1053	succinate dehydrogenase
CN260_RS24490	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CN260_RS24510	COG2076	Multidrug Resistance protein
CN260_RS24515	COG5510	response to toxic substance
CN260_RS24530	COG1509	lysine 2,3-aminomutase activity
CN260_RS24595	COG0531	amino acid
CN260_RS24600	COG3030	protein affecting phage T7 exclusion by the F plasmid
CN260_RS24610	COG1027	Aspartate ammonia-lyase
CN260_RS24615	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CN260_RS24630	COG1309	transcriptional regulator
CN260_RS24680	COG0457	Tetratricopeptide repeat
CN260_RS24685	COG1649	PFAM Uncharacterised BCR, COG1649
CN260_RS24685	COG0726	polysaccharide deacetylase
CN260_RS24690	COG1215	transferase activity, transferring glycosyl groups
CN260_RS24710	COG0861	Integral membrane protein TerC family
CN260_RS24740	COG1486	melibiose metabolic process
CN260_RS24750	COG2169	Transcriptional regulator
CN260_RS24765	COG2824	Alkylphosphonate utilization operon protein PhnA
CN260_RS24770	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CN260_RS24775	COG2188	Transcriptional regulator
CN260_RS24780	COG3624	Phosphonate C-P lyase system protein PhnG
CN260_RS24785	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CN260_RS24790	COG3626	phosphonate metabolism
CN260_RS24795	COG3627	carbon phosphorus lyase activity
CN260_RS24800	COG4107	phosphonate C-P lyase system protein PhnK
CN260_RS24805	COG4778	phosphonate C-P lyase system protein PhnL
CN260_RS24810	COG3454	Phosphonate metabolism
CN260_RS24820	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CN260_RS24830	COG4191	Histidine kinase
CN260_RS24830	COG0784	Response regulator, receiver
CN260_RS24835	COG1129	ABC transporter
CN260_RS24840	COG1172	Belongs to the binding-protein-dependent transport system permease family
CN260_RS24875	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CN260_RS24880	COG1301	dicarboxylic acid transport
CN260_RS24890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CN260_RS24900	COG3162	membrane
CN260_RS24930	COG3539	Fimbrial protein
CN260_RS24935	COG1346	cytolysis
CN260_RS24940	COG1380	Effector of murein hydrolase LrgA
CN260_RS24945	COG0583	DNA-binding transcription factor activity
CN260_RS24950	COG0025	NhaP-type Na H and K H
CN260_RS24955	COG2252	PERMEase
CN260_RS24960	COG0625	glutathione transferase activity
CN260_RS24965	COG0789	Transcriptional regulator
CN260_RS24975	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CN260_RS25010	COG1234	tRNA 3'-trailer cleavage
CN260_RS25015	COG1609	Transcriptional regulator
CN260_RS25020	COG0483	inositol monophosphate 1-phosphatase activity
CN260_RS25035	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CN260_RS25055	COG4771	TonB-dependent receptor
CN260_RS25060	COG0741	lytic transglycosylase activity
CN260_RS25080	COG2315	Protein conserved in bacteria
CN260_RS25085	COG0432	Pfam Uncharacterised protein family UPF0047
CN260_RS25100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CN260_RS25105	COG0305	Participates in initiation and elongation during chromosome replication
CN260_RS25120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CN260_RS25130	COG0735	belongs to the Fur family
CN260_RS25135	COG3237	CsbD-like
CN260_RS25140	COG0534	Mate efflux family protein
CN260_RS25150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CN260_RS25225	COG0251	oxidation-reduction process
CN260_RS25235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CN260_RS25255	COG0527	aspartate kinase activity
CN260_RS25310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CN260_RS25340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CN260_RS25350	COG0456	acetyltransferase
CN260_RS25395	COG0151	Belongs to the GarS family
CN260_RS25405	COG4191	Histidine kinase
CN260_RS25410	COG3678	ATP-independent chaperone mediated protein folding
CN260_RS25445	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CN260_RS25460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CN260_RS25465	COG2104	thiamine diphosphate biosynthetic process
CN260_RS25485	COG3706	GGDEF domain
CN260_RS25495	COG1447	Phosphotransferase system cellobiose-specific component IIA
CN260_RS25500	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CN260_RS25540	COG0250	Participates in transcription elongation, termination and antitermination
CN260_RS25620	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CN260_RS25630	COG1739	Uncharacterized protein family UPF0029
CN260_RS25675	COG0805	protein transport
CN260_RS25695	COG3165	ubiquinone biosynthetic process from chorismate
CN260_RS25720	COG0641	radical SAM
CN260_RS25730	COG2149	membrane
CN260_RS25735	COG2188	Transcriptional regulator
CN260_RS25755	COG0583	DNA-binding transcription factor activity
CN260_RS25760	COG0697	spore germination
CN260_RS25765	COG0561	phosphatase activity
CN260_RS25770	COG2267	carboxylic ester hydrolase activity
CN260_RS25775	COG1280	lysine exporter protein (LysE YggA)
CN260_RS25785	COG1280	lysine exporter protein (LysE YggA)
CN260_RS25820	COG0210	DNA helicase
CN260_RS25825	COG1011	Hydrolase
CN260_RS25855	COG3072	Adenylate cyclase
CN260_RS25870	COG2959	enzyme of heme biosynthesis
CN260_RS25875	COG3071	HemY protein
CN260_RS25920	COG2244	polysaccharide biosynthetic process
CN260_RS25925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CN260_RS25930	COG0456	acetyltransferase
CN260_RS25935	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CN260_RS25940	COG1088	dTDP-glucose 4,6-dehydratase activity
CN260_RS25945	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CN260_RS25950	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CN260_RS25960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CN260_RS25965	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CN260_RS25975	COG3118	belongs to the thioredoxin family
CN260_RS26005	COG1811	Na channel or pump
CN260_RS26015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CN260_RS26020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CN260_RS26030	COG0583	DNA-binding transcription factor activity
CN260_RS26035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CN260_RS26050	COG3978	acetolactate synthase activity
CN260_RS26070	COG3085	chromosome segregation
CN260_RS26145	COG0583	DNA-binding transcription factor activity
CN260_RS26170	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CN260_RS26185	COG3443	Belongs to the bacterial solute-binding protein 9 family
CN260_RS26190	COG2207	Transcriptional regulator
CN260_RS26200	COG0371	Dehydrogenase
CN260_RS26205	COG0697	spore germination
CN260_RS26215	COG0583	DNA-binding transcription factor activity
CN260_RS26225	COG0737	Belongs to the 5'-nucleotidase family
CN260_RS26235	COG0527	aspartate kinase activity
CN260_RS26235	COG0460	homoserine dehydrogenase
CN260_RS26240	COG0626	cystathionine gamma-synthase activity
CN260_RS26255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CN260_RS26260	COG1609	Transcriptional regulator
CN260_RS26265	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CN260_RS26280	COG1575	Belongs to the MenA family. Type 1 subfamily
CN260_RS26300	COG3678	ATP-independent chaperone mediated protein folding
CN260_RS26305	COG0745	RESPONSE REGULATOR receiver
CN260_RS26310	COG2205	protein histidine kinase activity
CN260_RS26315	COG2258	MOSC domain
CN260_RS26320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CN260_RS26365	COG1129	ABC transporter
CN260_RS26370	COG1172	Belongs to the binding-protein-dependent transport system permease family
CN260_RS26375	COG1172	Belongs to the binding-protein-dependent transport system permease family
CN260_RS26380	COG1454	alcohol dehydrogenase
CN260_RS26390	COG2211	Major facilitator Superfamily
CN260_RS26450	COG0205	6-phosphofructokinase activity
CN260_RS26470	COG0243	molybdopterin cofactor binding
CN260_RS26470	COG3383	formate dehydrogenase (NAD+) activity
CN260_RS26475	COG0243	molybdopterin cofactor binding
CN260_RS26475	COG3383	formate dehydrogenase (NAD+) activity
CN260_RS26480	COG0437	4 iron, 4 sulfur cluster binding
CN260_RS26485	COG2864	formate dehydrogenase
CN260_RS26500	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CN260_RS26510	COG0456	acetyltransferase
CN260_RS26525	COG1011	Hydrolase
CN260_RS26545	COG3852	Histidine kinase
CN260_RS26555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CN260_RS26585	COG0204	Acyl-transferase
CN260_RS26595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CN260_RS26600	COG3084	Protein conserved in bacteria
CN260_RS26610	COG1763	Mo-molybdopterin cofactor biosynthetic process
CN260_RS26645	COG2186	Transcriptional regulator
CN260_RS26650	COG0477	Major facilitator Superfamily
CN260_RS26655	COG1609	Transcriptional regulator
CN260_RS26660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CN260_RS26670	COG1172	Belongs to the binding-protein-dependent transport system permease family
CN260_RS26675	COG1129	ABC transporter
CN260_RS26705	COG1522	sequence-specific DNA binding
CN260_RS26710	COG0716	FMN binding
CN260_RS26725	COG3312	ion transport
CN260_RS26775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CN260_RS26780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CN260_RS26785	COG0573	inorganic phosphate transmembrane transporter activity
CN260_RS26790	COG0581	inorganic phosphate transmembrane transporter activity
CN260_RS26795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CN260_RS26800	COG0704	Plays a role in the regulation of phosphate uptake
CN260_RS26815	COG2382	esterase
CN260_RS26820	COG0363	glucosamine-6-phosphate deaminase activity
CN260_RS26825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CN260_RS26835	COG2252	PERMEase
CN260_RS26840	COG0431	NADPH-dependent FMN reductase
CN260_RS26845	COG2091	lysine biosynthetic process via aminoadipic acid
CN260_RS26880	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CN260_RS26955	COG1396	sequence-specific DNA binding
CN260_RS26960	COG4598	ABC transporter
CN260_RS26970	COG4215	(ABC) transporter
CN260_RS27015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CN260_RS27020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CN260_RS27025	COG4598	ABC transporter
CN260_RS27030	COG4160	amino acid transport
CN260_RS27035	COG4215	(ABC) transporter
CN260_RS27040	COG2988	succinylglutamate desuccinylase activity
CN260_RS27045	COG1012	belongs to the aldehyde dehydrogenase family
CN260_RS27050	COG3138	arginine N-succinyltransferase
CN260_RS27055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CN260_RS27065	COG2423	ornithine cyclodeaminase activity
CN260_RS27100	COG2826	transposase and inactivated derivatives, IS30 family
CN260_RS27155	COG3547	Transposase (IS116 IS110 IS902 family)
CN260_RS27170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CN260_RS27175	COG0501	Belongs to the peptidase M48B family
CN260_RS27230	COG0542	response to heat
CN260_RS27235	COG0071	Belongs to the small heat shock protein (HSP20) family
CN260_RS27285	COG0110	maltose O-acetyltransferase activity
CN260_RS27290	COG2223	nitrite transmembrane transporter activity
CN260_RS27300	COG1609	Transcriptional regulator
CN260_RS27335	COG0431	NADPH-dependent FMN reductase
CN260_RS27370	COG3436	PFAM IS66 Orf2 family protein
CN260_RS27375	COG1120	ATPase activity
CN260_RS27380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CN260_RS27385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CN260_RS27390	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CN260_RS27395	COG4772	TonB-dependent receptor
CN260_RS27400	COG3712	iron ion homeostasis
CN260_RS27405	COG1595	DNA-templated transcription, initiation
CN260_RS27450	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CN260_RS27480	COG0739	heme binding
CN260_RS27490	COG2132	Multicopper oxidase
CN260_RS27495	COG3667	copper resistance
CN260_RS27500	COG2372	response to copper ion
CN260_RS27505	COG1276	copper resistance
CN260_RS27510	COG0745	RESPONSE REGULATOR receiver
CN260_RS27515	COG2205	protein histidine kinase activity
CN260_RS27565	COG3436	PFAM IS66 Orf2 family protein
CN260_RS27580	COG4680	protein conserved in bacteria
CN260_RS27585	COG5499	transcription regulator containing HTH domain
CN260_RS27610	COG5642	Protein of unknown function (DUF2384)
CN260_RS27615	COG5654	RES domain protein
CN260_RS27685	COG3436	PFAM IS66 Orf2 family protein
CN260_RS27690	COG4372	Transposase
CN260_RS27785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CN260_RS27845	COG2801	Transposase and inactivated derivatives
CN260_RS27860	COG2801	Transposase and inactivated derivatives
CN260_RS27875	COG2916	Histone family protein nucleoid-structuring protein H-NS
CN260_RS27960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CN260_RS27990	COG2188	Transcriptional regulator
CN260_RS27995	COG0402	S-adenosylhomocysteine deaminase activity
CN260_RS28005	COG2801	Transposase and inactivated derivatives
CN260_RS28020	COG2200	EAL domain
CN260_RS28020	COG2203	Gaf domain
CN260_RS28020	COG2199	diguanylate cyclase activity
CN260_RS28030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CN260_RS28035	COG0318	PFAM AMP-dependent synthetase and ligase
CN260_RS28050	COG1662	PFAM IS1 transposase
CN260_RS28050	COG3677	Transposase
CN260_RS28135	COG4598	ABC transporter
CN260_RS28140	COG0765	amino acid transport
CN260_RS28145	COG0765	amino acid transport
CN260_RS28155	COG0583	DNA-binding transcription factor activity
CN260_RS28175	COG1401	restriction endodeoxyribonuclease activity
CN260_RS28175	COG1401	restriction endodeoxyribonuclease activity
CN260_RS28305	COG1358	cellular component organization or biogenesis
CN260_RS28325	COG4245	von Willebrand factor, type A
CN260_RS28335	COG4245	von Willebrand factor, type A
CN260_RS28340	COG4245	von Willebrand factor, type A
CN260_RS28360	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
CN260_RS28375	COG1609	Transcriptional regulator
CN260_RS28385	COG2223	nitrite transmembrane transporter activity
CN260_RS28390	COG0110	maltose O-acetyltransferase activity
CN260_RS28540	COG4372	Transposase
CN260_RS28545	COG3436	PFAM IS66 Orf2 family protein
CN260_RS28625	COG0789	Transcriptional regulator
CN260_RS28680	COG3385	transposase activity
CN260_RS28745	COG0625	glutathione transferase activity
CN260_RS28750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CN260_RS28760	COG0583	DNA-binding transcription factor activity
CN260_RS28770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CN260_RS28785	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CN260_RS28805	COG1846	Transcriptional regulator
CN260_RS28810	COG0583	DNA-binding transcription factor activity
CN260_RS28820	COG2948	multi-organism process
CN260_RS28875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CN260_RS28925	COG0058	SHG alpha-glucan phosphorylase activity
CN260_RS28930	COG0033	Phosphoglucomutase
CN260_RS28950	COG2801	Transposase and inactivated derivatives
CN260_RS28965	COG2801	Transposase and inactivated derivatives
CN260_RS29035	COG1192	Involved in chromosome partitioning
CN260_RS29600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CN260_RS29630	COG2003	Belongs to the UPF0758 family
CN260_RS29825	COG0629	single-stranded DNA binding
CN260_RS30130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CN260_RS30200	COG1349	DNA-binding transcription factor activity
CN260_RS30420	COG1802	Transcriptional regulator
CN260_RS30420	COG4626	Terminase
CN260_RS30525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CN260_RS30700	COG0616	signal peptide processing
