locus-tag	class	description
A8C11_RS00110	COG0534	Mate efflux family protein
A8C11_RS00130	COG1169	isochorismate synthase
A8C11_RS00245	COG2226	methyltransferase
A8C11_RS01605	COG2723	6-phospho-beta-galactosidase activity
A8C11_RS01725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C11_RS01725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C11_RS01725	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A8C11_RS01795	COG0523	cobalamin synthesis protein
A8C11_RS01895	COG0025	NhaP-type Na H and K H
A8C11_RS02050	COG2226	methyltransferase
A8C11_RS02050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A8C11_RS02050	COG3433	isochorismatase activity
A8C11_RS02415	COG0025	NhaP-type Na H and K H
A8C11_RS02420	COG1309	transcriptional regulator
A8C11_RS02425	COG0604	alcohol dehydrogenase
A8C11_RS02445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A8C11_RS02455	COG0534	Mate efflux family protein
A8C11_RS02470	COG0582	viral genome integration into host DNA
A8C11_RS02475	COG1169	isochorismate synthase
A8C11_RS02480	COG2814	Major facilitator Superfamily
A8C11_RS02485	COG1132	(ABC) transporter
A8C11_RS02500	COG3433	isochorismatase activity
A8C11_RS02500	COG2226	methyltransferase
A8C11_RS02500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A8C11_RS02520	COG1021	2,3-dihydroxybenzoate-AMP ligase
A8C11_RS02525	COG4771	TonB-dependent receptor
A8C11_RS02660	COG3621	Patatin-like phospholipase
A8C11_RS02690	COG3706	GGDEF domain
A8C11_RS02715	COG3615	Tellurite resistance protein tehB
A8C11_RS02725	COG3300	MHYT domain
A8C11_RS02725	COG5001	Diguanylate cyclase
A8C11_RS02735	COG0477	Major facilitator Superfamily
A8C11_RS02740	COG0095	Lipoate-protein ligase
A8C11_RS02745	COG0583	DNA-binding transcription factor activity
A8C11_RS02750	COG1942	4-Oxalocrotonate Tautomerase
A8C11_RS02760	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A8C11_RS02780	COG1289	transmembrane transporter activity
A8C11_RS02790	COG3344	reverse transcriptase
A8C11_RS02800	COG2925	Exonuclease
A8C11_RS02805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A8C11_RS02810	COG0640	Transcriptional regulator
A8C11_RS02815	COG0531	amino acid
A8C11_RS02820	COG0583	DNA-binding transcription factor activity
A8C11_RS02825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8C11_RS02850	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A8C11_RS02870	COG1215	transferase activity, transferring glycosyl groups
A8C11_RS02880	COG0438	transferase activity, transferring glycosyl groups
A8C11_RS03015	COG1253	flavin adenine dinucleotide binding
A8C11_RS03020	COG2982	Protein involved in outer membrane biogenesis
A8C11_RS03035	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A8C11_RS03040	COG0443	Heat shock 70 kDa protein
A8C11_RS03065	COG1301	dicarboxylic acid transport
A8C11_RS03090	COG2205	protein histidine kinase activity
A8C11_RS03095	COG0745	RESPONSE REGULATOR receiver
A8C11_RS03100	COG0826	peptidase U32
A8C11_RS03110	COG4608	Belongs to the ABC transporter superfamily
A8C11_RS03115	COG0444	Belongs to the ABC transporter superfamily
A8C11_RS03120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C11_RS03125	COG0601	transmembrane transport
A8C11_RS03135	COG4948	Mandelate Racemase Muconate Lactonizing
A8C11_RS03140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8C11_RS03150	COG1070	Carbohydrate kinase
A8C11_RS03185	COG1830	Aldolase
A8C11_RS03190	COG0351	phosphomethylpyrimidine kinase
A8C11_RS03210	COG0583	DNA-binding transcription factor activity
A8C11_RS03220	COG2252	PERMEase
A8C11_RS03225	COG0583	DNA-binding transcription factor activity
A8C11_RS03230	COG5455	response to cobalt ion
A8C11_RS03250	COG4807	Protein conserved in bacteria
A8C11_RS03260	COG3275	phosphorelay sensor kinase activity
A8C11_RS03270	COG1174	glycine betaine transport
A8C11_RS03275	COG1125	glycine betaine transport
A8C11_RS03280	COG1174	glycine betaine transport
A8C11_RS03285	COG1732	Glycine betaine
A8C11_RS03290	COG1472	Belongs to the glycosyl hydrolase 3 family
A8C11_RS03295	COG0277	FAD linked oxidase domain protein
A8C11_RS03305	COG1686	Belongs to the peptidase S11 family
A8C11_RS03315	COG0586	Pfam SNARE associated Golgi protein
A8C11_RS03320	COG1538	Outer membrane efflux protein
A8C11_RS03330	COG2723	6-phospho-beta-galactosidase activity
A8C11_RS03345	COG3659	wide pore channel activity
A8C11_RS03350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A8C11_RS03360	COG1346	cytolysis
A8C11_RS03370	COG2949	membrane
A8C11_RS03380	COG1129	ABC transporter
A8C11_RS03395	COG2311	Membrane
A8C11_RS03410	COG4771	TonB-dependent receptor
A8C11_RS03415	COG0833	amino acid
A8C11_RS03420	COG0583	DNA-binding transcription factor activity
A8C11_RS03430	COG2855	membrane
A8C11_RS03440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C11_RS03440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C11_RS03440	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A8C11_RS03445	COG1105	Belongs to the carbohydrate kinase PfkB family
A8C11_RS03450	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS03450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS03470	COG1312	Catalyzes the dehydration of D-mannonate
A8C11_RS03475	COG0246	Mannitol dehydrogenase
A8C11_RS03480	COG0523	cobalamin synthesis protein
A8C11_RS03485	COG0671	phosphoesterase, PA-phosphatase related
A8C11_RS03490	COG0791	NLP P60 protein
A8C11_RS03495	COG2200	EAL domain
A8C11_RS03500	COG4166	transmembrane transport
A8C11_RS03505	COG4174	ABC transporter (Permease)
A8C11_RS03510	COG4239	(ABC) transporter, permease
A8C11_RS03515	COG4172	Belongs to the ABC transporter superfamily
A8C11_RS03525	COG2814	Major facilitator Superfamily
A8C11_RS03530	COG1187	pseudouridine synthase activity
A8C11_RS03535	COG1061	Type III restriction enzyme res subunit
A8C11_RS03555	COG0494	nUDIX hydrolase
A8C11_RS03560	COG1349	DNA-binding transcription factor activity
A8C11_RS03585	COG0628	permease
A8C11_RS03600	COG0659	secondary active sulfate transmembrane transporter activity
A8C11_RS03605	COG2239	Acts as a magnesium transporter
A8C11_RS03610	COG4615	Cyclic peptide transporter
A8C11_RS03615	COG3145	DNA-N1-methyladenine dioxygenase activity
A8C11_RS03620	COG2169	Transcriptional regulator
A8C11_RS03620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A8C11_RS03635	COG0642	Histidine kinase
A8C11_RS03635	COG2198	Histidine kinase
A8C11_RS03645	COG0784	Response regulator, receiver
A8C11_RS03645	COG2205	protein histidine kinase activity
A8C11_RS03670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8C11_RS03680	COG2271	Major facilitator Superfamily
A8C11_RS03685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A8C11_RS03695	COG0247	lactate metabolic process
A8C11_RS03705	COG2271	Major facilitator Superfamily
A8C11_RS03715	COG1414	Transcriptional regulator
A8C11_RS03740	COG5464	transposase or invertase
A8C11_RS03750	COG0318	PFAM AMP-dependent synthetase and ligase
A8C11_RS03775	COG1169	isochorismate synthase
A8C11_RS03780	COG2153	protein acetylation
A8C11_RS03795	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8C11_RS03800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A8C11_RS03810	COG0839	Belongs to the complex I subunit 6 family
A8C11_RS03860	COG0583	DNA-binding transcription factor activity
A8C11_RS03865	COG0436	Aminotransferase
A8C11_RS03875	COG0471	metal ion transport
A8C11_RS03875	COG0490	domain, Protein
A8C11_RS03880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8C11_RS03900	COG0280	phosphate acetyltransferase
A8C11_RS03900	COG0857	belongs to the CobB CobQ family
A8C11_RS03905	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
A8C11_RS03910	COG0622	Phosphoesterase
A8C11_RS03915	COG0625	glutathione transferase activity
A8C11_RS03920	COG0625	glutathione transferase activity
A8C11_RS03925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A8C11_RS03930	COG1090	epimerase
A8C11_RS03945	COG4598	ABC transporter
A8C11_RS03950	COG4160	amino acid transport
A8C11_RS03975	COG0163	prenyltransferase activity
A8C11_RS03980	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A8C11_RS03985	COG1286	toxin biosynthetic process
A8C11_RS03990	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
A8C11_RS03995	COG0285	dihydrofolate synthase activity
A8C11_RS04005	COG0586	Pfam SNARE associated Golgi protein
A8C11_RS04015	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A8C11_RS04035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A8C11_RS04050	COG3101	peptidyl-lysine hydroxylation
A8C11_RS04075	COG2062	phosphohistidine phosphatase, SixA
A8C11_RS04090	COG3691	Protein conserved in bacteria
A8C11_RS04100	COG2853	Lipoprotein
A8C11_RS04105	COG2116	formate transmembrane transporter activity
A8C11_RS04125	COG0583	DNA-binding transcription factor activity
A8C11_RS04130	COG0590	tRNA wobble adenosine to inosine editing
A8C11_RS04135	COG2807	transmembrane transport
A8C11_RS04140	COG0436	Aminotransferase
A8C11_RS04155	COG3275	phosphorelay sensor kinase activity
A8C11_RS04160	COG3279	Response regulator of the LytR AlgR family
A8C11_RS04175	COG3961	Belongs to the TPP enzyme family
A8C11_RS04180	COG0667	Aldo Keto reductase
A8C11_RS04195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C11_RS04200	COG2200	EAL domain
A8C11_RS04200	COG2199	diguanylate cyclase activity
A8C11_RS04210	COG3415	Transposase
A8C11_RS04215	COG3415	Transposase
A8C11_RS04240	COG0583	DNA-binding transcription factor activity
A8C11_RS04245	COG0385	Bile acid
A8C11_RS04250	COG3530	Putative quorum-sensing-regulated virulence factor
A8C11_RS04275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A8C11_RS04315	COG4319	ketosteroid isomerase
A8C11_RS04325	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A8C11_RS04330	COG4208	sulfate ABC transporter
A8C11_RS04335	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A8C11_RS04340	COG4150	thiosulfate binding
A8C11_RS04355	COG2837	iron assimilation
A8C11_RS04375	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8C11_RS04465	COG4810	utilization protein
A8C11_RS04475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A8C11_RS04480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A8C11_RS04485	COG5342	invasion associated locus B
A8C11_RS04495	COG0493	'glutamate synthase
A8C11_RS04495	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8C11_RS04500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8C11_RS04505	COG1393	Belongs to the ArsC family
A8C11_RS04520	COG0400	carboxylic ester hydrolase activity
A8C11_RS04525	COG1444	tRNA N-acetyltransferase activity
A8C11_RS04530	COG2321	neutral zinc metallopeptidase
A8C11_RS04540	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
A8C11_RS04550	COG2716	regulation of RNA biosynthetic process
A8C11_RS04555	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A8C11_RS04560	COG0628	permease
A8C11_RS04570	COG4783	chaperone-mediated protein folding
A8C11_RS04575	COG1393	Belongs to the ArsC family
A8C11_RS04590	COG2233	PERMEase
A8C11_RS04600	COG2723	6-phospho-beta-galactosidase activity
A8C11_RS04615	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A8C11_RS04630	COG2200	EAL domain
A8C11_RS04650	COG0641	radical SAM
A8C11_RS04655	COG3119	arylsulfatase activity
A8C11_RS04665	COG0517	IMP dehydrogenase activity
A8C11_RS04665	COG0516	GMP reductase activity
A8C11_RS04675	COG1645	bacterial-type flagellum-dependent swarming motility
A8C11_RS04700	COG0758	DNA mediated transformation
A8C11_RS04700	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A8C11_RS04825	COG2976	Protein conserved in bacteria
A8C11_RS04855	COG4953	penicillin-binding protein 1C
A8C11_RS04860	COG2373	Large extracellular alpha-helical protein
A8C11_RS04865	COG2897	thiosulfate sulfurtransferase activity
A8C11_RS04885	COG2975	iron-sulfur cluster assembly
A8C11_RS04890	COG0633	Ferredoxin
A8C11_RS04910	COG0822	iron-sulfur transferase activity
A8C11_RS04940	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
A8C11_RS04945	COG3683	transport system, periplasmic component
A8C11_RS04950	COG3711	transcriptional antiterminator
A8C11_RS04955	COG2814	Major facilitator Superfamily
A8C11_RS04960	COG2017	converts alpha-aldose to the beta-anomer
A8C11_RS04965	COG0477	Major facilitator Superfamily
A8C11_RS04965	COG2814	Major facilitator Superfamily
A8C11_RS04970	COG0457	Tetratricopeptide repeat
A8C11_RS04975	COG1940	carbohydrate kinase activity
A8C11_RS04980	COG2259	Doxx family
A8C11_RS04990	COG1017	nitric oxide dioxygenase activity
A8C11_RS04990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8C11_RS04995	COG0347	Belongs to the P(II) protein family
A8C11_RS05000	COG2204	response regulator
A8C11_RS05005	COG3170	Tfp pilus assembly protein FimV
A8C11_RS05010	COG2205	protein histidine kinase activity
A8C11_RS05015	COG0047	phosphoribosylformylglycinamidine synthase activity
A8C11_RS05015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A8C11_RS05030	COG0560	Phosphoserine phosphatase
A8C11_RS05035	COG1737	Transcriptional regulator
A8C11_RS05040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8C11_RS05050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A8C11_RS05075	COG0681	Belongs to the peptidase S26 family
A8C11_RS05125	COG1196	nuclear chromosome segregation
A8C11_RS05210	COG3728	DNA packaging
A8C11_RS05210	COG5484	DNA packaging
A8C11_RS05235	COG3179	chitinase
A8C11_RS05250	COG0484	heat shock protein binding
A8C11_RS05260	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
A8C11_RS05305	COG1484	DNA-dependent DNA replication
A8C11_RS05350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8C11_RS05385	COG3086	response to oxidative stress
A8C11_RS05390	COG3026	antisigma factor binding
A8C11_RS05395	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
A8C11_RS05405	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A8C11_RS05415	COG0513	Belongs to the DEAD box helicase family
A8C11_RS05430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8C11_RS05435	COG3118	belongs to the thioredoxin family
A8C11_RS05440	COG3148	PFAM DTW domain containing protein
A8C11_RS05450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8C11_RS05455	COG5544	Lipoprotein
A8C11_RS05460	COG0477	Major facilitator Superfamily
A8C11_RS05490	COG0542	response to heat
A8C11_RS05505	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8C11_RS05510	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A8C11_RS05515	COG1605	Chorismate mutase
A8C11_RS05515	COG0077	Prephenate dehydratase
A8C11_RS05525	COG1605	Chorismate mutase
A8C11_RS05525	COG0287	Prephenate dehydrogenase
A8C11_RS05530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A8C11_RS05540	COG2199	diguanylate cyclase activity
A8C11_RS05545	COG2885	chlorophyll binding
A8C11_RS05585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A8C11_RS05590	COG4137	Cytochrome C assembly protein
A8C11_RS05595	COG4536	flavin adenine dinucleotide binding
A8C11_RS05610	COG0497	DNA recombination
A8C11_RS05630	COG2867	negative regulation of translational initiation
A8C11_RS05660	COG3708	Transcriptional regulator
A8C11_RS05660	COG2207	Transcriptional regulator
A8C11_RS05665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C11_RS05700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C11_RS05710	COG0235	Class ii aldolase
A8C11_RS05720	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS05735	COG2197	response regulator
A8C11_RS05740	COG3539	Fimbrial protein
A8C11_RS05750	COG3188	usher protein
A8C11_RS05770	COG3121	Chaperone
A8C11_RS05775	COG3539	Fimbrial protein
A8C11_RS05785	COG3284	Transcriptional regulator
A8C11_RS05790	COG0583	DNA-binding transcription factor activity
A8C11_RS05800	COG0640	Transcriptional regulator
A8C11_RS05805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8C11_RS05820	COG2916	Histone family protein nucleoid-structuring protein H-NS
A8C11_RS05840	COG4575	ribosome binding
A8C11_RS05845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C11_RS05850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8C11_RS05855	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A8C11_RS05865	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A8C11_RS05880	COG4176	ABC-type proline glycine betaine transport system permease component
A8C11_RS05890	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A8C11_RS05905	COG1846	Transcriptional regulator
A8C11_RS05915	COG1566	PFAM secretion protein HlyD family protein
A8C11_RS05920	COG2814	Major facilitator Superfamily
A8C11_RS05925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A8C11_RS05945	COG1238	metal cluster binding
A8C11_RS05950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8C11_RS05955	COG2823	Periplasmic or secreted lipoprotein
A8C11_RS05990	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A8C11_RS06010	COG1546	Belongs to the CinA family
A8C11_RS06015	COG0803	Belongs to the bacterial solute-binding protein 9 family
A8C11_RS06020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8C11_RS06025	COG1121	(ABC) transporter
A8C11_RS06030	COG2951	lytic endotransglycosylase activity
A8C11_RS06035	COG3730	PTS system glucitol sorbitol-specific
A8C11_RS06040	COG3732	PTS system glucitol sorbitol-specific
A8C11_RS06050	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS06055	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS06060	COG1349	DNA-binding transcription factor activity
A8C11_RS06090	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A8C11_RS06095	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A8C11_RS06100	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8C11_RS06105	COG1609	Transcriptional regulator
A8C11_RS06115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C11_RS06115	COG1263	PTS System
A8C11_RS06120	COG2723	6-phospho-beta-galactosidase activity
A8C11_RS06130	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A8C11_RS06140	COG3260	NADH ubiquinone oxidoreductase 20
A8C11_RS06145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8C11_RS06150	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A8C11_RS06150	COG3261	NADH dehydrogenase
A8C11_RS06155	COG0650	Formate hydrogenlyase subunit 4
A8C11_RS06160	COG0651	ATP synthesis coupled electron transport
A8C11_RS06165	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8C11_RS06180	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A8C11_RS06185	COG0298	carbon dioxide binding
A8C11_RS06190	COG0409	Hydrogenase expression formation protein
A8C11_RS06195	COG0309	Hydrogenase expression formation protein (HypE)
A8C11_RS06205	COG2723	6-phospho-beta-galactosidase activity
A8C11_RS06215	COG4580	involved in the transport of maltose and maltodextrins
A8C11_RS06220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS06225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS06230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS06235	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8C11_RS06240	COG1940	carbohydrate kinase activity
A8C11_RS06245	COG1609	Transcriptional regulator
A8C11_RS06250	COG0803	Belongs to the bacterial solute-binding protein 9 family
A8C11_RS06255	COG1121	(ABC) transporter
A8C11_RS06260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8C11_RS06265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8C11_RS06280	COG0679	Auxin Efflux Carrier
A8C11_RS06300	COG3720	iron ion transport
A8C11_RS06305	COG4558	Periplasmic binding protein
A8C11_RS06310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C11_RS06345	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A8C11_RS06350	COG0163	prenyltransferase activity
A8C11_RS06375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A8C11_RS06380	COG4942	peptidase
A8C11_RS06380	COG1388	LysM domain
A8C11_RS06440	COG2234	aminopeptidase activity
A8C11_RS06465	COG0720	synthase
A8C11_RS06470	COG0602	queuosine metabolic process
A8C11_RS06495	COG3956	TIGRFAM MazG family protein
A8C11_RS06500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A8C11_RS06510	COG3437	response regulator, receiver
A8C11_RS06510	COG4999	Histidine kinase
A8C11_RS06510	COG3850	Histidine kinase
A8C11_RS06510	COG2205	protein histidine kinase activity
A8C11_RS06515	COG1929	Belongs to the glycerate kinase type-1 family
A8C11_RS06520	COG4948	Mandelate Racemase Muconate Lactonizing
A8C11_RS06525	COG4948	Mandelate Racemase Muconate Lactonizing
A8C11_RS06530	COG2271	Major facilitator Superfamily
A8C11_RS06535	COG0716	FMN binding
A8C11_RS06540	COG0564	pseudouridine synthase activity
A8C11_RS06545	COG3098	single-species biofilm formation
A8C11_RS06560	COG1611	Belongs to the LOG family
A8C11_RS06565	COG0814	amino acid
A8C11_RS06570	COG1760	l-serine dehydratase
A8C11_RS06575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8C11_RS06585	COG0477	Major facilitator Superfamily
A8C11_RS06590	COG1464	Belongs to the NlpA lipoprotein family
A8C11_RS06595	COG2011	ABC-type metal ion transport system permease component
A8C11_RS06600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A8C11_RS06615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C11_RS06635	COG1454	alcohol dehydrogenase
A8C11_RS06640	COG0235	Class ii aldolase
A8C11_RS06650	COG0738	Major facilitator superfamily
A8C11_RS06670	COG1349	DNA-binding transcription factor activity
A8C11_RS06680	COG2363	Small membrane protein
A8C11_RS06685	COG0583	DNA-binding transcription factor activity
A8C11_RS06695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A8C11_RS06700	COG2166	iron-sulfur cluster assembly
A8C11_RS06705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A8C11_RS06710	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A8C11_RS06745	COG2885	chlorophyll binding
A8C11_RS06940	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
A8C11_RS06970	COG1454	alcohol dehydrogenase
A8C11_RS06970	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS06975	COG4656	Part of a membrane complex involved in electron transport
A8C11_RS07005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A8C11_RS07010	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8C11_RS07015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A8C11_RS07015	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A8C11_RS07025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A8C11_RS07030	COG1074	ATP-dependent DNA helicase activity
A8C11_RS07035	COG1025	Belongs to the peptidase M16 family
A8C11_RS07040	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A8C11_RS07045	COG4967	type IV pilus modification protein PilV
A8C11_RS07055	COG4795	General secretion pathway protein
A8C11_RS07060	COG2165	general secretion pathway protein
A8C11_RS07095	COG0861	Integral membrane protein TerC family
A8C11_RS07105	COG0667	Aldo Keto reductase
A8C11_RS07125	COG1609	Transcriptional regulator
A8C11_RS07135	COG2186	Transcriptional regulator
A8C11_RS07140	COG2723	6-phospho-beta-galactosidase activity
A8C11_RS07145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS07150	COG1609	Transcriptional regulator
A8C11_RS07160	COG0583	DNA-binding transcription factor activity
A8C11_RS07165	COG1794	racemase activity, acting on amino acids and derivatives
A8C11_RS07170	COG1917	Cupin 2, conserved barrel domain protein
A8C11_RS07175	COG1175	transmembrane transport
A8C11_RS07180	COG0395	ABC-type sugar transport system, permease component
A8C11_RS07185	COG3842	ATPase activity
A8C11_RS07220	COG2814	Major facilitator Superfamily
A8C11_RS07225	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS07235	COG0823	Involved in the tonB-independent uptake of proteins
A8C11_RS07245	COG0183	Belongs to the thiolase family
A8C11_RS07260	COG0814	amino acid
A8C11_RS07265	COG0667	Aldo Keto reductase
A8C11_RS07315	COG0697	spore germination
A8C11_RS07320	COG1846	Transcriptional regulator
A8C11_RS07325	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
A8C11_RS07335	COG0582	viral genome integration into host DNA
A8C11_RS07340	COG4974	Belongs to the 'phage' integrase family
A8C11_RS07360	COG3121	Chaperone
A8C11_RS07365	COG3188	usher protein
A8C11_RS07370	COG3539	Fimbrial protein
A8C11_RS07375	COG3539	Fimbrial protein
A8C11_RS07380	COG3539	Fimbrial protein
A8C11_RS07390	COG2388	GCN5-related N-acetyl-transferase
A8C11_RS07395	COG3592	Divergent 4Fe-4S mono-cluster
A8C11_RS07410	COG1289	transmembrane transporter activity
A8C11_RS07415	COG1538	Outer membrane efflux protein
A8C11_RS07430	COG1393	Belongs to the ArsC family
A8C11_RS07435	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A8C11_RS07475	COG0667	Aldo Keto reductase
A8C11_RS07490	COG2814	Major facilitator Superfamily
A8C11_RS07500	COG4942	peptidase
A8C11_RS07505	COG0583	DNA-binding transcription factor activity
A8C11_RS07510	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A8C11_RS07520	COG1811	Na channel or pump
A8C11_RS07540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A8C11_RS07550	COG4974	Belongs to the 'phage' integrase family
A8C11_RS07555	COG0716	FMN binding
A8C11_RS07565	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
A8C11_RS07575	COG1272	protein, Hemolysin III
A8C11_RS07585	COG1737	Transcriptional regulator
A8C11_RS07590	COG2723	6-phospho-beta-galactosidase activity
A8C11_RS07610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8C11_RS07615	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS07635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8C11_RS07640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8C11_RS07645	COG0006	proline dipeptidase activity
A8C11_RS07665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A8C11_RS07670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8C11_RS07690	COG2968	Membrane
A8C11_RS07705	COG0668	transmembrane transport
A8C11_RS07710	COG0191	fructose-bisphosphate aldolase activity
A8C11_RS07725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A8C11_RS07730	COG0501	Belongs to the peptidase M48B family
A8C11_RS07755	COG2814	Major facilitator Superfamily
A8C11_RS07765	COG2356	endonuclease I
A8C11_RS07770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A8C11_RS07775	COG0189	ligase activity
A8C11_RS07800	COG2805	Type II/IV secretion system protein
A8C11_RS07805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A8C11_RS07810	COG0762	integral membrane protein
A8C11_RS07825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A8C11_RS07840	COG4214	carbohydrate transport
A8C11_RS07850	COG3171	Protein conserved in bacteria
A8C11_RS07860	COG1194	a g-specific adenine glycosylase
A8C11_RS07875	COG2211	Major facilitator Superfamily
A8C11_RS07880	COG1982	Orn Lys Arg decarboxylase major
A8C11_RS07885	COG1811	Na channel or pump
A8C11_RS07905	COG3188	usher protein
A8C11_RS07910	COG3121	Chaperone
A8C11_RS07915	COG3121	Chaperone
A8C11_RS07930	COG3121	Chaperone
A8C11_RS07945	COG0626	cystathionine gamma-synthase activity
A8C11_RS07950	COG0583	DNA-binding transcription factor activity
A8C11_RS07970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C11_RS07975	COG0754	glutathionylspermidine amidase activity
A8C11_RS07990	COG0625	glutathione transferase activity
A8C11_RS08015	COG2211	Major facilitator Superfamily
A8C11_RS08020	COG0848	biopolymer transport protein
A8C11_RS08035	COG0626	cystathionine gamma-synthase activity
A8C11_RS08040	COG0586	Pfam SNARE associated Golgi protein
A8C11_RS08045	COG2207	Transcriptional regulator
A8C11_RS08050	COG1979	alcohol dehydrogenase
A8C11_RS08055	COG0656	L-ascorbic acid biosynthetic process
A8C11_RS08065	COG1032	radical SAM domain protein
A8C11_RS08070	COG2132	Multicopper oxidase
A8C11_RS08075	COG0204	Acyl-transferase
A8C11_RS08080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A8C11_RS08090	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
A8C11_RS08095	COG3111	PFAM Bacterial OB fold (BOF) protein
A8C11_RS08105	COG0642	Histidine kinase
A8C11_RS08110	COG2249	NAD(P)H dehydrogenase (quinone) activity
A8C11_RS08115	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A8C11_RS08125	COG3150	esterase
A8C11_RS08130	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A8C11_RS08135	COG3151	Protein conserved in bacteria
A8C11_RS08140	COG0494	nUDIX hydrolase
A8C11_RS08155	COG0754	glutathionylspermidine amidase activity
A8C11_RS08160	COG3384	dioxygenase
A8C11_RS08175	COG2960	long-chain fatty acid transporting porin activity
A8C11_RS08200	COG3025	triphosphatase activity
A8C11_RS08205	COG4991	sh3 domain protein
A8C11_RS08220	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A8C11_RS08290	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A8C11_RS08295	COG0358	DNA primase activity
A8C11_RS08300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A8C11_RS08325	COG2197	response regulator
A8C11_RS08330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C11_RS08330	COG2205	protein histidine kinase activity
A8C11_RS08330	COG2198	Histidine kinase
A8C11_RS08330	COG0784	Response regulator, receiver
A8C11_RS08340	COG3247	response to pH
A8C11_RS08410	COG2376	Dihydroxyacetone kinase
A8C11_RS08415	COG1461	Dihydroxyacetone kinase
A8C11_RS08440	COG1695	Transcriptional regulator
A8C11_RS08490	COG1902	pentaerythritol trinitrate reductase activity
A8C11_RS08490	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8C11_RS08510	COG1451	nucleotide metabolic process
A8C11_RS08515	COG0673	inositol 2-dehydrogenase activity
A8C11_RS08520	COG0861	Integral membrane protein TerC family
A8C11_RS08535	COG2721	sulfolactate sulfo-lyase activity
A8C11_RS08545	COG2271	Major facilitator Superfamily
A8C11_RS08550	COG2186	Transcriptional regulator
A8C11_RS08555	COG0586	Pfam SNARE associated Golgi protein
A8C11_RS08565	COG1422	Protein of unknown function (DUF1090)
A8C11_RS08570	COG4575	ribosome binding
A8C11_RS08575	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
A8C11_RS08585	COG2259	Doxx family
A8C11_RS08590	COG0435	Glutathione S-transferase
A8C11_RS08595	COG3152	Membrane
A8C11_RS08600	COG0583	DNA-binding transcription factor activity
A8C11_RS08605	COG1741	Belongs to the pirin family
A8C11_RS08635	COG1929	Belongs to the glycerate kinase type-1 family
A8C11_RS08640	COG2084	Dehydrogenase
A8C11_RS08650	COG2271	Major facilitator Superfamily
A8C11_RS08660	COG2721	sulfolactate sulfo-lyase activity
A8C11_RS08665	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A8C11_RS08685	COG2823	Periplasmic or secreted lipoprotein
A8C11_RS08690	COG0701	Predicted permease
A8C11_RS08695	COG0702	epimerase
A8C11_RS08700	COG0693	protein deglycase activity
A8C11_RS08715	COG3153	acetyltransferase
A8C11_RS08720	COG3154	lipid carrier protein
A8C11_RS08725	COG0826	peptidase U32
A8C11_RS08730	COG0826	peptidase U32
A8C11_RS08735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C11_RS08740	COG0814	amino acid
A8C11_RS08785	COG0195	Participates in both transcription termination and antitermination
A8C11_RS08830	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A8C11_RS08840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A8C11_RS08845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A8C11_RS08855	COG1534	Rna-binding protein
A8C11_RS08865	COG2027	D-alanyl-D-alanine carboxypeptidase
A8C11_RS08875	COG0697	spore germination
A8C11_RS08890	COG0142	geranyltranstransferase activity
A8C11_RS08895	COG3423	Transcriptional regulator
A8C11_RS08905	COG5007	Belongs to the BolA IbaG family
A8C11_RS08910	COG3113	response to antibiotic
A8C11_RS08915	COG2854	intermembrane phospholipid transfer
A8C11_RS08920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A8C11_RS08925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A8C11_RS08930	COG1127	ABC transporter
A8C11_RS08935	COG0530	calcium, potassium:sodium antiporter activity
A8C11_RS08945	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A8C11_RS08950	COG3117	lipopolysaccharide transmembrane transporter activity
A8C11_RS08955	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A8C11_RS08960	COG1137	ATPase activity
A8C11_RS08965	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A8C11_RS08970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A8C11_RS08975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS08985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS08990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A8C11_RS08995	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
A8C11_RS09000	COG5002	protein histidine kinase activity
A8C11_RS09000	COG0784	Response regulator, receiver
A8C11_RS09000	COG2198	Histidine kinase
A8C11_RS09005	COG1312	Catalyzes the dehydration of D-mannonate
A8C11_RS09015	COG1063	alcohol dehydrogenase
A8C11_RS09020	COG2271	Major facilitator Superfamily
A8C11_RS09025	COG1242	4 iron, 4 sulfur cluster binding
A8C11_RS09030	COG0070	glutamate synthase
A8C11_RS09030	COG0069	glutamate synthase activity
A8C11_RS09030	COG0067	glutamate synthase
A8C11_RS09035	COG0493	'glutamate synthase
A8C11_RS09045	COG2969	positive regulation of protein catabolic process
A8C11_RS09050	COG0625	glutathione transferase activity
A8C11_RS09065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A8C11_RS09070	COG3105	Protein conserved in bacteria
A8C11_RS09075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8C11_RS09080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8C11_RS09105	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A8C11_RS09110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A8C11_RS09115	COG0471	metal ion transport
A8C11_RS09150	COG2732	(Barnase) inhibitor
A8C11_RS09155	COG1289	transmembrane transporter activity
A8C11_RS09170	COG0583	DNA-binding transcription factor activity
A8C11_RS09175	COG0312	modulator of DNA gyrase
A8C11_RS09180	COG3164	Protein of unknown function
A8C11_RS09185	COG1530	ribonuclease E activity
A8C11_RS09195	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A8C11_RS09200	COG1792	Involved in formation and maintenance of cell shape
A8C11_RS09205	COG1077	Cell shape determining protein MreB Mrl
A8C11_RS09210	COG2200	EAL domain
A8C11_RS09210	COG2199	diguanylate cyclase activity
A8C11_RS09235	COG0511	ligase activity, forming carbon-carbon bonds
A8C11_RS09240	COG0439	Biotin carboxylase
A8C11_RS09245	COG3924	membrane
A8C11_RS09270	COG1309	transcriptional regulator
A8C11_RS09275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C11_RS09280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8C11_RS09315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A8C11_RS09345	COG0758	DNA mediated transformation
A8C11_RS09375	COG0789	Transcriptional regulator
A8C11_RS09390	COG0202	RNA polymerase activity
A8C11_RS09410	COG0201	protein transport
A8C11_RS09475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A8C11_RS09490	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A8C11_RS09515	COG0051	transcription antitermination factor activity, RNA binding
A8C11_RS09570	COG2964	Protein conserved in bacteria
A8C11_RS09575	COG0545	Peptidyl-prolyl cis-trans isomerase
A8C11_RS09585	COG1047	Peptidyl-prolyl cis-trans
A8C11_RS09590	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
A8C11_RS09605	COG0488	(ABC) transporter
A8C11_RS09615	COG0429	hydrolase of the alpha beta-hydrolase fold
A8C11_RS09625	COG3954	Phosphoribulokinase
A8C11_RS09630	COG1765	OsmC-like protein
A8C11_RS09640	COG1289	transmembrane transporter activity
A8C11_RS09645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A8C11_RS09670	COG0738	Major facilitator superfamily
A8C11_RS09675	COG0402	S-adenosylhomocysteine deaminase activity
A8C11_RS09685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A8C11_RS09710	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A8C11_RS09715	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A8C11_RS09720	COG3266	domain, Protein
A8C11_RS09735	COG4796	Type ii and iii secretion system protein
A8C11_RS09755	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A8C11_RS09760	COG0494	nUDIX hydrolase
A8C11_RS09770	COG1011	Hydrolase
A8C11_RS09775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A8C11_RS09805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A8C11_RS09810	COG2183	response to ionizing radiation
A8C11_RS09815	COG1918	ferrous iron import across plasma membrane
A8C11_RS09840	COG1040	competence protein
A8C11_RS09850	COG2610	gluconate transmembrane transporter activity
A8C11_RS09855	COG1640	4-alpha-glucanotransferase
A8C11_RS09860	COG0058	SHG alpha-glucan phosphorylase activity
A8C11_RS09870	COG1349	DNA-binding transcription factor activity
A8C11_RS09885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A8C11_RS09890	COG0058	SHG alpha-glucan phosphorylase activity
A8C11_RS09915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A8C11_RS09925	COG2610	gluconate transmembrane transporter activity
A8C11_RS09930	COG3265	gluconokinase activity
A8C11_RS09935	COG1609	Transcriptional regulator
A8C11_RS09940	COG1741	Belongs to the pirin family
A8C11_RS09945	COG0673	inositol 2-dehydrogenase activity
A8C11_RS09955	COG1247	-acetyltransferase
A8C11_RS09960	COG0405	Gamma-glutamyltransferase
A8C11_RS09970	COG0584	glycerophosphoryl diester phosphodiesterase
A8C11_RS10020	COG0559	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS10025	COG0683	leucine binding
A8C11_RS10040	COG0683	leucine binding
A8C11_RS10055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A8C11_RS10070	COG2177	Part of the ABC transporter FtsEX involved in
A8C11_RS10075	COG2884	Cell division ATP-binding protein ftsE
A8C11_RS10080	COG0552	protein localization to endoplasmic reticulum
A8C11_RS10085	COG0742	ribosomal rna small subunit methyltransferase
A8C11_RS10090	COG3776	membrane
A8C11_RS10100	COG3714	YhhN family
A8C11_RS10115	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A8C11_RS10125	COG0477	Major facilitator Superfamily
A8C11_RS10130	COG0628	permease
A8C11_RS10170	COG3479	Phenolic acid decarboxylase
A8C11_RS10180	COG0747	negative chemotaxis
A8C11_RS10185	COG0601	transmembrane transport
A8C11_RS10190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C11_RS10200	COG1124	(ABC) transporter
A8C11_RS10215	COG2239	Acts as a magnesium transporter
A8C11_RS10245	COG1196	nuclear chromosome segregation
A8C11_RS10250	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A8C11_RS10280	COG2081	HI0933 family
A8C11_RS10285	COG0306	phosphate transporter
A8C11_RS10295	COG0589	response to stress
A8C11_RS10315	COG0671	phosphoesterase, PA-phosphatase related
A8C11_RS10320	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A8C11_RS10325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8C11_RS10335	COG1454	alcohol dehydrogenase
A8C11_RS10345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C11_RS10350	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS10355	COG0583	DNA-binding transcription factor activity
A8C11_RS10360	COG1295	ribonuclease BN
A8C11_RS10365	COG0477	Major facilitator Superfamily
A8C11_RS10370	COG2982	Protein involved in outer membrane biogenesis
A8C11_RS10385	COG0612	Peptidase, M16
A8C11_RS10395	COG2200	EAL domain
A8C11_RS10395	COG2199	diguanylate cyclase activity
A8C11_RS10405	COG3118	belongs to the thioredoxin family
A8C11_RS10405	COG0457	Tetratricopeptide repeat
A8C11_RS10410	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A8C11_RS10415	COG1215	transferase activity, transferring glycosyl groups
A8C11_RS10445	COG2194	sulfuric ester hydrolase activity
A8C11_RS10460	COG0457	Tetratricopeptide repeat
A8C11_RS10465	COG1215	transferase activity, transferring glycosyl groups
A8C11_RS10475	COG2894	cell division
A8C11_RS10490	COG4608	Belongs to the ABC transporter superfamily
A8C11_RS10495	COG0444	Belongs to the ABC transporter superfamily
A8C11_RS10500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C11_RS10505	COG0601	transmembrane transport
A8C11_RS10510	COG0747	negative chemotaxis
A8C11_RS10535	COG2223	nitrite transmembrane transporter activity
A8C11_RS10540	COG5571	outer membrane autotransporter
A8C11_RS10545	COG2818	Glycosylase
A8C11_RS10550	COG0456	acetyltransferase
A8C11_RS10555	COG0243	molybdopterin cofactor binding
A8C11_RS10560	COG2885	chlorophyll binding
A8C11_RS10570	COG1609	Transcriptional regulator
A8C11_RS10580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C11_RS10600	COG2814	Major facilitator Superfamily
A8C11_RS10605	COG2944	sequence-specific DNA binding
A8C11_RS10610	COG1278	Cold shock
A8C11_RS10645	COG3274	enterobacterial common antigen metabolic process
A8C11_RS10650	COG4682	membrane
A8C11_RS10655	COG4682	membrane
A8C11_RS10670	COG4213	ABC transporter substrate-binding protein
A8C11_RS10680	COG4214	carbohydrate transport
A8C11_RS10685	COG1609	Transcriptional regulator
A8C11_RS10685	COG2207	Transcriptional regulator
A8C11_RS10690	COG2992	FlgJ-related protein
A8C11_RS10695	COG0366	Alpha amylase catalytic
A8C11_RS10700	COG3977	Valine--pyruvate aminotransferase
A8C11_RS10705	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8C11_RS10710	COG3276	selenocysteine insertion sequence binding
A8C11_RS10720	COG0625	glutathione transferase activity
A8C11_RS10735	COG3722	fumarate hydratase activity
A8C11_RS10755	COG2186	Transcriptional regulator
A8C11_RS10765	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A8C11_RS10785	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A8C11_RS10790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8C11_RS10800	COG4942	peptidase
A8C11_RS10805	COG2861	carbohydrate metabolic process
A8C11_RS10810	COG0463	Glycosyl transferase, family 2
A8C11_RS10820	COG0156	8-amino-7-oxononanoate synthase activity
A8C11_RS10835	COG0859	PFAM glycosyl transferase family 9
A8C11_RS10860	COG0859	PFAM glycosyl transferase family 9
A8C11_RS10870	COG0438	transferase activity, transferring glycosyl groups
A8C11_RS10875	COG1216	Glycosyl transferase, family 2
A8C11_RS10880	COG1519	Transferase
A8C11_RS10915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A8C11_RS10945	COG0842	Transport permease protein
A8C11_RS10950	COG1131	(ABC) transporter
A8C11_RS10970	COG1561	YicC-like family, N-terminal region
A8C11_RS10980	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A8C11_RS10985	COG2169	Transcriptional regulator
A8C11_RS10985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A8C11_RS10995	COG2860	membrane
A8C11_RS11015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A8C11_RS11020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8C11_RS11025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A8C11_RS11030	COG1494	fructose-1,6-bisphosphatase
A8C11_RS11040	COG3152	Membrane
A8C11_RS11065	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A8C11_RS11070	COG3074	FtsZ-dependent cytokinesis
A8C11_RS11085	COG0786	glutamate:sodium symporter activity
A8C11_RS11095	COG2233	PERMEase
A8C11_RS11100	COG2982	Protein involved in outer membrane biogenesis
A8C11_RS11105	COG1263	PTS System
A8C11_RS11105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C11_RS11110	COG1486	melibiose metabolic process
A8C11_RS11120	COG1501	Belongs to the glycosyl hydrolase 31 family
A8C11_RS11125	COG2211	Major facilitator Superfamily
A8C11_RS11155	COG1064	alcohol dehydrogenase
A8C11_RS11165	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A8C11_RS11180	COG1464	Belongs to the NlpA lipoprotein family
A8C11_RS11205	COG0583	DNA-binding transcription factor activity
A8C11_RS11245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8C11_RS11255	COG2814	Major facilitator Superfamily
A8C11_RS11265	COG1263	PTS System
A8C11_RS11265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C11_RS11270	COG0697	spore germination
A8C11_RS11285	COG2828	Protein conserved in bacteria
A8C11_RS11290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A8C11_RS11295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A8C11_RS11300	COG0583	DNA-binding transcription factor activity
A8C11_RS11315	COG1609	Transcriptional regulator
A8C11_RS11325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS11325	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS11330	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8C11_RS11335	COG4580	involved in the transport of maltose and maltodextrins
A8C11_RS11360	COG2188	Transcriptional regulator
A8C11_RS11400	COG2271	Major facilitator Superfamily
A8C11_RS11410	COG2197	response regulator
A8C11_RS11415	COG0440	acetolactate synthase activity
A8C11_RS11420	COG0028	Belongs to the TPP enzyme family
A8C11_RS11440	COG2814	Major facilitator Superfamily
A8C11_RS11445	COG0583	DNA-binding transcription factor activity
A8C11_RS11455	COG2610	gluconate transmembrane transporter activity
A8C11_RS11475	COG2149	membrane
A8C11_RS11490	COG2188	Transcriptional regulator
A8C11_RS11500	COG3645	SOS response
A8C11_RS11515	COG5645	(Lipo)protein
A8C11_RS11520	COG0823	Involved in the tonB-independent uptake of proteins
A8C11_RS11525	COG2271	Major facilitator Superfamily
A8C11_RS11535	COG0800	Aldolase
A8C11_RS11540	COG3734	2-keto-3-deoxy-galactonokinase
A8C11_RS11545	COG2186	Transcriptional regulator
A8C11_RS11560	COG0561	phosphatase activity
A8C11_RS11565	COG0187	DNA topoisomerase II activity
A8C11_RS11595	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A8C11_RS11625	COG2091	lysine biosynthetic process via aminoadipic acid
A8C11_RS11630	COG0431	NADPH-dependent FMN reductase
A8C11_RS11635	COG2252	PERMEase
A8C11_RS11645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8C11_RS11650	COG0363	glucosamine-6-phosphate deaminase activity
A8C11_RS11655	COG2382	esterase
A8C11_RS11670	COG0704	Plays a role in the regulation of phosphate uptake
A8C11_RS11675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A8C11_RS11680	COG0581	inorganic phosphate transmembrane transporter activity
A8C11_RS11685	COG0573	inorganic phosphate transmembrane transporter activity
A8C11_RS11690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A8C11_RS11755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A8C11_RS11820	COG3312	ion transport
A8C11_RS11835	COG0716	FMN binding
A8C11_RS11840	COG1522	sequence-specific DNA binding
A8C11_RS11870	COG1129	ABC transporter
A8C11_RS11875	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS11885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C11_RS11890	COG1609	Transcriptional regulator
A8C11_RS11895	COG0477	Major facilitator Superfamily
A8C11_RS11900	COG2186	Transcriptional regulator
A8C11_RS11925	COG1763	Mo-molybdopterin cofactor biosynthetic process
A8C11_RS11935	COG3084	Protein conserved in bacteria
A8C11_RS11940	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A8C11_RS11950	COG0204	Acyl-transferase
A8C11_RS11970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A8C11_RS11980	COG3852	Histidine kinase
A8C11_RS12000	COG1011	Hydrolase
A8C11_RS12015	COG0456	acetyltransferase
A8C11_RS12025	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A8C11_RS12040	COG2864	formate dehydrogenase
A8C11_RS12045	COG0437	4 iron, 4 sulfur cluster binding
A8C11_RS12050	COG3383	formate dehydrogenase (NAD+) activity
A8C11_RS12050	COG0243	molybdopterin cofactor binding
A8C11_RS12055	COG3383	formate dehydrogenase (NAD+) activity
A8C11_RS12055	COG0243	molybdopterin cofactor binding
A8C11_RS12095	COG2211	Major facilitator Superfamily
A8C11_RS12105	COG1454	alcohol dehydrogenase
A8C11_RS12110	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS12115	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS12120	COG1129	ABC transporter
A8C11_RS12160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A8C11_RS12165	COG2258	MOSC domain
A8C11_RS12170	COG2205	protein histidine kinase activity
A8C11_RS12175	COG0745	RESPONSE REGULATOR receiver
A8C11_RS12180	COG3678	ATP-independent chaperone mediated protein folding
A8C11_RS12200	COG1575	Belongs to the MenA family. Type 1 subfamily
A8C11_RS12215	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A8C11_RS12220	COG1609	Transcriptional regulator
A8C11_RS12230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A8C11_RS12245	COG0626	cystathionine gamma-synthase activity
A8C11_RS12250	COG0460	homoserine dehydrogenase
A8C11_RS12250	COG0527	aspartate kinase activity
A8C11_RS12260	COG0737	Belongs to the 5'-nucleotidase family
A8C11_RS12270	COG0583	DNA-binding transcription factor activity
A8C11_RS12280	COG0697	spore germination
A8C11_RS12285	COG0371	Dehydrogenase
A8C11_RS12295	COG2207	Transcriptional regulator
A8C11_RS12300	COG3443	Belongs to the bacterial solute-binding protein 9 family
A8C11_RS12315	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A8C11_RS12330	COG0583	DNA-binding transcription factor activity
A8C11_RS12405	COG3085	chromosome segregation
A8C11_RS12425	COG3978	acetolactate synthase activity
A8C11_RS12440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A8C11_RS12445	COG0583	DNA-binding transcription factor activity
A8C11_RS12455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8C11_RS12460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8C11_RS12470	COG1811	Na channel or pump
A8C11_RS12495	COG3118	belongs to the thioredoxin family
A8C11_RS12500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A8C11_RS12505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A8C11_RS12515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A8C11_RS12520	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A8C11_RS12525	COG1088	dTDP-glucose 4,6-dehydratase activity
A8C11_RS12530	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A8C11_RS12535	COG0456	acetyltransferase
A8C11_RS12540	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A8C11_RS12545	COG2244	polysaccharide biosynthetic process
A8C11_RS12595	COG3071	HemY protein
A8C11_RS12600	COG2959	enzyme of heme biosynthesis
A8C11_RS12620	COG3072	Adenylate cyclase
A8C11_RS12650	COG1011	Hydrolase
A8C11_RS12655	COG0210	DNA helicase
A8C11_RS12690	COG1280	lysine exporter protein (LysE YggA)
A8C11_RS12700	COG1280	lysine exporter protein (LysE YggA)
A8C11_RS12705	COG2267	carboxylic ester hydrolase activity
A8C11_RS12710	COG0561	phosphatase activity
A8C11_RS12715	COG0697	spore germination
A8C11_RS12720	COG0583	DNA-binding transcription factor activity
A8C11_RS12750	COG3165	ubiquinone biosynthetic process from chorismate
A8C11_RS12770	COG0805	protein transport
A8C11_RS12815	COG1739	Uncharacterized protein family UPF0029
A8C11_RS12825	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
A8C11_RS12855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A8C11_RS12900	COG0250	Participates in transcription elongation, termination and antitermination
A8C11_RS12935	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A8C11_RS12940	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8C11_RS12950	COG3706	GGDEF domain
A8C11_RS12970	COG2104	thiamine diphosphate biosynthetic process
A8C11_RS12975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A8C11_RS12990	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
A8C11_RS13025	COG3678	ATP-independent chaperone mediated protein folding
A8C11_RS13035	COG4191	Histidine kinase
A8C11_RS13045	COG0151	Belongs to the GarS family
A8C11_RS13085	COG0456	acetyltransferase
A8C11_RS13095	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A8C11_RS13145	COG0527	aspartate kinase activity
A8C11_RS13155	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A8C11_RS13165	COG0251	oxidation-reduction process
A8C11_RS13235	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A8C11_RS13245	COG0534	Mate efflux family protein
A8C11_RS13255	COG3237	CsbD-like
A8C11_RS13260	COG0735	belongs to the Fur family
A8C11_RS13275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A8C11_RS13290	COG0305	Participates in initiation and elongation during chromosome replication
A8C11_RS13295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A8C11_RS13310	COG0432	Pfam Uncharacterised protein family UPF0047
A8C11_RS13315	COG2315	Protein conserved in bacteria
A8C11_RS13330	COG0741	lytic transglycosylase activity
A8C11_RS13340	COG4771	TonB-dependent receptor
A8C11_RS13365	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8C11_RS13375	COG0483	inositol monophosphate 1-phosphatase activity
A8C11_RS13380	COG1609	Transcriptional regulator
A8C11_RS13385	COG1234	tRNA 3'-trailer cleavage
A8C11_RS13415	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A8C11_RS13425	COG0789	Transcriptional regulator
A8C11_RS13430	COG0625	glutathione transferase activity
A8C11_RS13435	COG2252	PERMEase
A8C11_RS13440	COG0025	NhaP-type Na H and K H
A8C11_RS13445	COG0583	DNA-binding transcription factor activity
A8C11_RS13450	COG1380	Effector of murein hydrolase LrgA
A8C11_RS13455	COG1346	cytolysis
A8C11_RS13465	COG3539	Fimbrial protein
A8C11_RS13495	COG3162	membrane
A8C11_RS13505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A8C11_RS13515	COG1301	dicarboxylic acid transport
A8C11_RS13520	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
A8C11_RS13525	COG3383	formate dehydrogenase (NAD+) activity
A8C11_RS13530	COG3383	formate dehydrogenase (NAD+) activity
A8C11_RS13565	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS13570	COG1129	ABC transporter
A8C11_RS13575	COG0784	Response regulator, receiver
A8C11_RS13575	COG4191	Histidine kinase
A8C11_RS13585	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A8C11_RS13595	COG3454	Phosphonate metabolism
A8C11_RS13600	COG4778	phosphonate C-P lyase system protein PhnL
A8C11_RS13605	COG4107	phosphonate C-P lyase system protein PhnK
A8C11_RS13610	COG3627	carbon phosphorus lyase activity
A8C11_RS13615	COG3626	phosphonate metabolism
A8C11_RS13620	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
A8C11_RS13625	COG3624	Phosphonate C-P lyase system protein PhnG
A8C11_RS13630	COG2188	Transcriptional regulator
A8C11_RS13635	COG2764	glyoxalase bleomycin resistance protein dioxygenase
A8C11_RS13640	COG2824	Alkylphosphonate utilization operon protein PhnA
A8C11_RS13655	COG2169	Transcriptional regulator
A8C11_RS13660	COG1486	melibiose metabolic process
A8C11_RS13700	COG0861	Integral membrane protein TerC family
A8C11_RS13720	COG1215	transferase activity, transferring glycosyl groups
A8C11_RS13725	COG1649	PFAM Uncharacterised BCR, COG1649
A8C11_RS13725	COG0726	polysaccharide deacetylase
A8C11_RS13730	COG0457	Tetratricopeptide repeat
A8C11_RS13770	COG1309	transcriptional regulator
A8C11_RS13785	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A8C11_RS13790	COG1027	Aspartate ammonia-lyase
A8C11_RS13800	COG3030	protein affecting phage T7 exclusion by the F plasmid
A8C11_RS13805	COG0531	amino acid
A8C11_RS13875	COG1509	lysine 2,3-aminomutase activity
A8C11_RS13890	COG5510	response to toxic substance
A8C11_RS13895	COG2076	Multidrug Resistance protein
A8C11_RS13915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A8C11_RS13920	COG1053	succinate dehydrogenase
A8C11_RS13935	COG3264	Mechanosensitive ion channel
A8C11_RS13935	COG1511	domain protein
A8C11_RS13955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C11_RS13980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A8C11_RS13985	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A8C11_RS13985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A8C11_RS13990	COG0802	atpase or kinase
A8C11_RS13995	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8C11_RS14015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A8C11_RS14020	COG0330	HflC and HflK could
A8C11_RS14025	COG0330	HflC and HflK could
A8C11_RS14040	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
A8C11_RS14055	COG0557	exoribonuclease II activity
A8C11_RS14060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8C11_RS14065	COG1960	acyl-CoA dehydrogenase activity
A8C11_RS14075	COG3650	response to hydrogen peroxide
A8C11_RS14080	COG1073	alpha beta
A8C11_RS14140	COG2965	DNA replication, synthesis of RNA primer
A8C11_RS14145	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A8C11_RS14155	COG3061	Opacity-associated protein A
A8C11_RS14160	COG0545	Peptidyl-prolyl cis-trans isomerase
A8C11_RS14165	COG1113	amino acid transport
A8C11_RS14175	COG0697	spore germination
A8C11_RS14185	COG0702	epimerase
A8C11_RS14190	COG1733	regulation of RNA biosynthetic process
A8C11_RS14205	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A8C11_RS14230	COG1253	flavin adenine dinucleotide binding
A8C11_RS14240	COG0729	surface antigen
A8C11_RS14245	COG2911	Protein conserved in bacteria
A8C11_RS14250	COG2105	PFAM AIG2 family protein
A8C11_RS14265	COG1879	ABC-type sugar transport system periplasmic component
A8C11_RS14275	COG1129	ABC transporter
A8C11_RS14280	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS14285	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS14295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A8C11_RS14320	COG0312	modulator of DNA gyrase
A8C11_RS14360	COG3964	amidohydrolase
A8C11_RS14375	COG2706	6-phosphogluconolactonase activity
A8C11_RS14380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS14380	COG3711	transcriptional antiterminator
A8C11_RS14385	COG3077	Addiction module antitoxin, RelB DinJ family
A8C11_RS14390	COG2026	Addiction module toxin, RelE StbE family
A8C11_RS14395	COG0602	queuosine metabolic process
A8C11_RS14425	COG1486	melibiose metabolic process
A8C11_RS14430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS14435	COG0366	Alpha amylase catalytic
A8C11_RS14440	COG1263	PTS System
A8C11_RS14440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C11_RS14470	COG2731	YhcH YjgK YiaL family protein
A8C11_RS14495	COG0525	valine-tRNA ligase activity
A8C11_RS14500	COG2927	DNA polymerase III (CHI subunit)
A8C11_RS14510	COG0795	lipopolysaccharide-transporting ATPase activity
A8C11_RS14515	COG0795	lipopolysaccharide-transporting ATPase activity
A8C11_RS14520	COG0433	COG0433 Predicted ATPase
A8C11_RS14535	COG3718	enzyme involved in inositol metabolism
A8C11_RS14545	COG0837	glucose binding
A8C11_RS14545	COG1737	Transcriptional regulator
A8C11_RS14550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C11_RS14560	COG3962	Belongs to the TPP enzyme family
A8C11_RS14570	COG1082	Xylose isomerase domain protein TIM barrel
A8C11_RS14585	COG3842	ATPase activity
A8C11_RS14590	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A8C11_RS14595	COG0395	ABC-type sugar transport system, permease component
A8C11_RS14600	COG1175	transmembrane transport
A8C11_RS14605	COG1064	alcohol dehydrogenase
A8C11_RS14610	COG0659	secondary active sulfate transmembrane transporter activity
A8C11_RS14615	COG0288	reversible hydration of carbon dioxide
A8C11_RS14625	COG0582	viral genome integration into host DNA
A8C11_RS14630	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
A8C11_RS14650	COG1196	nuclear chromosome segregation
A8C11_RS14655	COG1715	Restriction endonuclease
A8C11_RS14660	COG2963	transposase activity
A8C11_RS14705	COG2801	Transposase and inactivated derivatives
A8C11_RS14710	COG1216	Glycosyl transferase, family 2
A8C11_RS14720	COG3328	transposase activity
A8C11_RS14730	COG3507	Belongs to the glycosyl hydrolase 43 family
A8C11_RS14735	COG2211	Major facilitator Superfamily
A8C11_RS14740	COG2115	Belongs to the xylose isomerase family
A8C11_RS14745	COG4580	involved in the transport of maltose and maltodextrins
A8C11_RS14750	COG3272	Protein of unknown function (DUF1722)
A8C11_RS14770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A8C11_RS14785	COG0300	oxidoreductase activity
A8C11_RS14790	COG3631	Ketosteroid isomerase-related protein
A8C11_RS14795	COG0789	Transcriptional regulator
A8C11_RS14800	COG3040	lipid binding
A8C11_RS14810	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8C11_RS14815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C11_RS14820	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C11_RS14825	COG1538	Outer membrane efflux protein
A8C11_RS14835	COG0745	RESPONSE REGULATOR receiver
A8C11_RS14840	COG5002	protein histidine kinase activity
A8C11_RS14855	COG2850	peptidyl-arginine hydroxylation
A8C11_RS14890	COG0842	Transport permease protein
A8C11_RS14895	COG0842	Transport permease protein
A8C11_RS14895	COG1129	ABC transporter
A8C11_RS14900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C11_RS14905	COG3706	GGDEF domain
A8C11_RS14915	COG1879	ABC-type sugar transport system periplasmic component
A8C11_RS14920	COG1129	ABC transporter
A8C11_RS14925	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS14935	COG2249	NAD(P)H dehydrogenase (quinone) activity
A8C11_RS14940	COG0583	DNA-binding transcription factor activity
A8C11_RS14950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C11_RS14955	COG5457	Domain of unknown function (DUF1127)
A8C11_RS14965	COG1566	PFAM secretion protein HlyD family protein
A8C11_RS14980	COG1924	4 iron, 4 sulfur cluster binding
A8C11_RS14985	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
A8C11_RS15000	COG2733	membrane
A8C11_RS15010	COG2207	Transcriptional regulator
A8C11_RS15010	COG1917	Cupin 2, conserved barrel domain protein
A8C11_RS15015	COG5464	transposase or invertase
A8C11_RS15020	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS15030	COG0523	cobalamin synthesis protein
A8C11_RS15035	COG2879	small protein
A8C11_RS15040	COG1966	Carbon starvation protein
A8C11_RS15055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A8C11_RS15060	COG2368	4-hydroxyphenylacetate
A8C11_RS15080	COG3971	2-oxopent-4-enoate hydratase activity
A8C11_RS15090	COG3384	dioxygenase
A8C11_RS15095	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS15105	COG0179	Fumarylacetoacetate (FAA) hydrolase
A8C11_RS15115	COG1846	Transcriptional regulator
A8C11_RS15145	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
A8C11_RS15160	COG3734	2-keto-3-deoxy-galactonokinase
A8C11_RS15165	COG0800	Aldolase
A8C11_RS15170	COG1737	Transcriptional regulator
A8C11_RS15180	COG0456	acetyltransferase
A8C11_RS15180	COG1214	PFAM Peptidase M22, glycoprotease
A8C11_RS15185	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A8C11_RS15185	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A8C11_RS15200	COG3715	PTS system
A8C11_RS15205	COG3716	PTS system mannose fructose sorbose family IID component
A8C11_RS15210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A8C11_RS15220	COG5464	transposase or invertase
A8C11_RS15235	COG1484	DNA-dependent DNA replication
A8C11_RS15250	COG2966	Psort location CytoplasmicMembrane, score
A8C11_RS15270	COG2197	response regulator
A8C11_RS15275	COG2197	response regulator
A8C11_RS15280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A8C11_RS15285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS15285	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS15290	COG4114	ferric iron reductase
A8C11_RS15295	COG3706	GGDEF domain
A8C11_RS15330	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
A8C11_RS15335	COG0456	acetyltransferase
A8C11_RS15340	COG1011	Hydrolase
A8C11_RS15350	COG2823	Periplasmic or secreted lipoprotein
A8C11_RS15355	COG5487	UPF0391 membrane protein
A8C11_RS15360	COG4667	esterase of the alpha-beta hydrolase superfamily
A8C11_RS15365	COG0084	hydrolase, TatD family'
A8C11_RS15370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C11_RS15400	COG3726	membrane protein affecting hemolysin expression
A8C11_RS15405	COG0560	Phosphoserine phosphatase
A8C11_RS15410	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A8C11_RS15420	COG0488	(ABC) transporter
A8C11_RS15425	COG0741	lytic transglycosylase activity
A8C11_RS15445	COG3708	Transcriptional regulator
A8C11_RS15445	COG2207	Transcriptional regulator
A8C11_RS15450	COG3045	CreA protein
A8C11_RS15455	COG0745	RESPONSE REGULATOR receiver
A8C11_RS15460	COG2205	protein histidine kinase activity
A8C11_RS15465	COG4452	Inner membrane protein CreD
A8C11_RS15470	COG0745	RESPONSE REGULATOR receiver
A8C11_RS15475	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A8C11_RS15485	COG0527	aspartate kinase activity
A8C11_RS15485	COG0460	homoserine dehydrogenase
A8C11_RS15495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A8C11_RS15510	COG1115	amino acid carrier protein
A8C11_RS15515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A8C11_RS15520	COG0521	Mo-molybdopterin cofactor biosynthetic process
A8C11_RS15525	COG0477	Major facilitator Superfamily
A8C11_RS15530	COG1584	GPR1 FUN34 yaaH family protein
A8C11_RS15535	COG4735	regulation of single-species biofilm formation
A8C11_RS15560	COG0583	DNA-binding transcription factor activity
A8C11_RS15575	COG0196	riboflavin kinase activity
A8C11_RS15590	COG1047	Peptidyl-prolyl cis-trans
A8C11_RS15605	COG3152	Membrane
A8C11_RS15615	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A8C11_RS15635	COG0505	Belongs to the CarA family
A8C11_RS15680	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A8C11_RS15690	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A8C11_RS15695	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A8C11_RS15710	COG3493	citrate carrier protein
A8C11_RS15725	COG0564	pseudouridine synthase activity
A8C11_RS15735	COG0417	DNA replication proofreading
A8C11_RS15740	COG0235	Class ii aldolase
A8C11_RS15765	COG0586	Pfam SNARE associated Golgi protein
A8C11_RS15775	COG1178	ABC-type Fe3 transport system permease component
A8C11_RS15800	COG2814	Major facilitator Superfamily
A8C11_RS15805	COG2271	Major facilitator Superfamily
A8C11_RS15810	COG0583	DNA-binding transcription factor activity
A8C11_RS15820	COG0738	Major facilitator superfamily
A8C11_RS15865	COG0028	Belongs to the TPP enzyme family
A8C11_RS15875	COG1609	Transcriptional regulator
A8C11_RS15895	COG0768	penicillin binding
A8C11_RS15900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A8C11_RS15905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A8C11_RS15920	COG0772	Belongs to the SEDS family
A8C11_RS15945	COG0849	cell division
A8C11_RS15950	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A8C11_RS15970	COG0494	nUDIX hydrolase
A8C11_RS16000	COG1459	type II secretion system
A8C11_RS16005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A8C11_RS16010	COG4969	Belongs to the N-Me-Phe pilin family
A8C11_RS16020	COG3023	N-Acetylmuramoyl-L-alanine amidase
A8C11_RS16025	COG3725	Membrane protein required for beta-lactamase induction
A8C11_RS16030	COG3940	Belongs to the glycosyl hydrolase 43 family
A8C11_RS16035	COG2211	Major facilitator Superfamily
A8C11_RS16040	COG1113	amino acid transport
A8C11_RS16050	COG2186	Transcriptional regulator
A8C11_RS16055	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A8C11_RS16060	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8C11_RS16065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8C11_RS16080	COG3064	Membrane
A8C11_RS16125	COG2132	Multicopper oxidase
A8C11_RS16130	COG4993	Dehydrogenase
A8C11_RS16145	COG0288	reversible hydration of carbon dioxide
A8C11_RS16150	COG1131	(ABC) transporter
A8C11_RS16155	COG0842	Transport permease protein
A8C11_RS16160	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS16165	COG0726	polysaccharide deacetylase
A8C11_RS16185	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A8C11_RS16190	COG0617	tRNA 3'-terminal CCA addition
A8C11_RS16210	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A8C11_RS16215	COG1643	Atp-dependent helicase
A8C11_RS16310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A8C11_RS16315	COG4774	siderophore transport
A8C11_RS16320	COG1120	ATPase activity
A8C11_RS16325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8C11_RS16330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C11_RS16350	COG2860	membrane
A8C11_RS16370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8C11_RS16375	COG3835	regulator
A8C11_RS16390	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
A8C11_RS16395	COG0024	Methionine aminopeptidase
A8C11_RS16420	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A8C11_RS16430	COG0575	Belongs to the CDS family
A8C11_RS16435	COG0750	zinc metalloprotease
A8C11_RS16445	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
A8C11_RS16475	COG0587	DNA-directed DNA polymerase activity
A8C11_RS16485	COG1982	Orn Lys Arg decarboxylase major
A8C11_RS16490	COG0346	lactoylglutathione lyase activity
A8C11_RS16500	COG4568	rho-dependent transcription termination
A8C11_RS16515	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A8C11_RS16520	COG3015	lipoprotein NlpE involved in copper resistance
A8C11_RS16525	COG0791	NLP P60 protein
A8C11_RS16535	COG1720	tRNA m6t6A37 methyltransferase activity
A8C11_RS16545	COG1464	Belongs to the NlpA lipoprotein family
A8C11_RS16550	COG2011	ABC-type metal ion transport system permease component
A8C11_RS16560	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A8C11_RS16595	COG0656	L-ascorbic acid biosynthetic process
A8C11_RS16600	COG0583	DNA-binding transcription factor activity
A8C11_RS16615	COG2226	methyltransferase
A8C11_RS16620	COG1388	LysM domain
A8C11_RS16620	COG0741	lytic transglycosylase activity
A8C11_RS16630	COG2226	methyltransferase
A8C11_RS16640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8C11_RS16650	COG0583	DNA-binding transcription factor activity
A8C11_RS16660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A8C11_RS16665	COG1960	acyl-CoA dehydrogenase activity
A8C11_RS16675	COG0121	glutamine amidotransferase
A8C11_RS16680	COG3034	peptidoglycan biosynthetic process
A8C11_RS16700	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A8C11_RS16705	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A8C11_RS16720	COG2991	Protein conserved in bacteria
A8C11_RS16735	COG0454	-acetyltransferase
A8C11_RS16740	COG2195	Cleaves the N-terminal amino acid of tripeptides
A8C11_RS16760	COG1802	Transcriptional regulator
A8C11_RS16765	COG1113	amino acid transport
A8C11_RS16770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A8C11_RS16775	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS16780	COG0579	oxidoreductase
A8C11_RS16795	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A8C11_RS16800	COG0625	glutathione transferase activity
A8C11_RS16805	COG3775	system Galactitol-specific IIC component
A8C11_RS16810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8C11_RS16815	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS16820	COG1070	Carbohydrate kinase
A8C11_RS16840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8C11_RS16845	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8C11_RS16850	COG0022	dehydrogenase e1 component
A8C11_RS16855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A8C11_RS16880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A8C11_RS16910	COG0791	NLP P60 protein
A8C11_RS16930	COG3639	organic phosphonate transmembrane transporter activity
A8C11_RS16965	COG3188	usher protein
A8C11_RS16980	COG0765	amino acid transport
A8C11_RS16985	COG4597	amino acid ABC transporter
A8C11_RS16990	COG1126	abc transporter atp-binding protein
A8C11_RS16995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C11_RS17035	COG4302	ethanolamine ammonia-lyase activity
A8C11_RS17040	COG4303	Ethanolamine ammonia lyase large subunit
A8C11_RS17055	COG0833	amino acid
A8C11_RS17060	COG2040	homocysteine
A8C11_RS17065	COG4521	taurine ABC transporter
A8C11_RS17070	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A8C11_RS17075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C11_RS17080	COG2175	clavaminate synthase activity
A8C11_RS17090	COG0113	porphobilinogen synthase activity
A8C11_RS17095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A8C11_RS17100	COG1335	isochorismatase
A8C11_RS17105	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A8C11_RS17145	COG1785	Belongs to the alkaline phosphatase family
A8C11_RS17155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A8C11_RS17165	COG3416	Protein conserved in bacteria
A8C11_RS17170	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A8C11_RS17180	COG4126	flavin adenine dinucleotide binding
A8C11_RS17195	COG1940	carbohydrate kinase activity
A8C11_RS17200	COG0419	ATPase involved in DNA repair
A8C11_RS17205	COG0420	3'-5' exonuclease activity
A8C11_RS17230	COG0366	Alpha amylase catalytic
A8C11_RS17235	COG0583	DNA-binding transcription factor activity
A8C11_RS17240	COG1335	isochorismatase
A8C11_RS17250	COG1228	amidohydrolase
A8C11_RS17260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C11_RS17275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS17285	COG0450	alkyl hydroperoxide reductase
A8C11_RS17310	COG1862	Preprotein translocase
A8C11_RS17315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A8C11_RS17320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A8C11_RS17340	COG4238	major outer membrane lipoprotein
A8C11_RS17350	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A8C11_RS17350	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A8C11_RS17370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A8C11_RS17375	COG0667	Aldo Keto reductase
A8C11_RS17385	COG0142	geranyltranstransferase activity
A8C11_RS17405	COG0693	protein deglycase activity
A8C11_RS17410	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A8C11_RS17420	COG2814	Major facilitator Superfamily
A8C11_RS17425	COG0673	inositol 2-dehydrogenase activity
A8C11_RS17440	COG1053	succinate dehydrogenase
A8C11_RS17450	COG1053	succinate dehydrogenase
A8C11_RS17455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A8C11_RS17460	COG1414	Transcriptional regulator
A8C11_RS17475	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A8C11_RS17480	COG1845	cytochrome c oxidase, subunit III
A8C11_RS17485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A8C11_RS17490	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A8C11_RS17495	COG2223	nitrite transmembrane transporter activity
A8C11_RS17500	COG3056	Lipoprotein
A8C11_RS17505	COG0271	Belongs to the BolA IbaG family
A8C11_RS17525	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A8C11_RS17530	COG0776	regulation of translation
A8C11_RS17535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8C11_RS17540	COG1555	photosystem II stabilization
A8C11_RS17545	COG0824	Thioesterase
A8C11_RS17555	COG4533	DNA binding
A8C11_RS17570	COG1522	sequence-specific DNA binding
A8C11_RS17575	COG1132	(ABC) transporter
A8C11_RS17580	COG1132	(ABC) transporter
A8C11_RS17585	COG0347	Belongs to the P(II) protein family
A8C11_RS17590	COG0004	ammonium transporteR
A8C11_RS17595	COG1946	Acyl-CoA thioesterase
A8C11_RS17600	COG3126	Type III secretion system lipoprotein chaperone (YscW)
A8C11_RS17605	COG3695	enzyme binding
A8C11_RS17635	COG2364	Membrane
A8C11_RS17650	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A8C11_RS17665	COG2182	Extracellular solute-binding protein
A8C11_RS17670	COG1175	transmembrane transport
A8C11_RS17675	COG3833	ABC-type maltose transport systems, permease component
A8C11_RS17680	COG3867	Arabinogalactan endo-beta-1,4-galactanase
A8C11_RS17685	COG1874	Beta-galactosidase
A8C11_RS17735	COG0110	maltose O-acetyltransferase activity
A8C11_RS17750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8C11_RS17755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C11_RS17760	COG1309	transcriptional regulator
A8C11_RS17765	COG1196	nuclear chromosome segregation
A8C11_RS17765	COG3264	Mechanosensitive ion channel
A8C11_RS17770	COG5464	transposase or invertase
A8C11_RS17780	COG3923	Primosomal replication protein n
A8C11_RS17785	COG2832	Protein of unknown function (DUF454)
A8C11_RS17825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C11_RS17830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A8C11_RS17830	COG4651	solute:proton antiporter activity
A8C11_RS17845	COG2223	nitrite transmembrane transporter activity
A8C11_RS17855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A8C11_RS17860	COG3735	TraB family
A8C11_RS17875	COG1585	Membrane protein implicated in regulation of membrane protease activity
A8C11_RS17880	COG0330	HflC and HflK could
A8C11_RS17885	COG4619	ABC transporter
A8C11_RS17890	COG0390	transport system, permease component
A8C11_RS17895	COG3118	belongs to the thioredoxin family
A8C11_RS17900	COG0300	oxidoreductase activity
A8C11_RS17905	COG2755	lipolytic protein G-D-S-L family
A8C11_RS17910	COG4181	ATPase activity
A8C11_RS17915	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A8C11_RS17935	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A8C11_RS17940	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A8C11_RS17955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A8C11_RS17965	COG2501	S4 domain
A8C11_RS18010	COG1560	Kdo2-lipid A biosynthetic process
A8C11_RS18020	COG3710	Transcriptional regulator
A8C11_RS18025	COG0531	amino acid
A8C11_RS18030	COG1982	Orn Lys Arg decarboxylase major
A8C11_RS18035	COG3104	oligopeptide transport
A8C11_RS18065	COG0673	inositol 2-dehydrogenase activity
A8C11_RS18080	COG1129	ABC transporter
A8C11_RS18085	COG4211	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS18140	COG1566	PFAM secretion protein HlyD family protein
A8C11_RS18145	COG1120	ATPase activity
A8C11_RS18150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C11_RS18185	COG1473	amidohydrolase
A8C11_RS18190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C11_RS18195	COG0667	Aldo Keto reductase
A8C11_RS18235	COG4680	protein conserved in bacteria
A8C11_RS18250	COG0531	amino acid
A8C11_RS18260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A8C11_RS18265	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS18280	COG1113	amino acid transport
A8C11_RS18285	COG2211	Major facilitator Superfamily
A8C11_RS18295	COG0673	inositol 2-dehydrogenase activity
A8C11_RS18305	COG1609	Transcriptional regulator
A8C11_RS18310	COG0668	transmembrane transport
A8C11_RS18315	COG0477	Major facilitator Superfamily
A8C11_RS18340	COG0778	Nitroreductase
A8C11_RS18345	COG2315	Protein conserved in bacteria
A8C11_RS18390	COG3698	Phosphodiester glycosidase
A8C11_RS18400	COG4166	transmembrane transport
A8C11_RS18410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C11_RS18415	COG4608	Belongs to the ABC transporter superfamily
A8C11_RS18430	COG0697	spore germination
A8C11_RS18445	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
A8C11_RS18450	COG0765	amino acid transport
A8C11_RS18455	COG4215	(ABC) transporter
A8C11_RS18465	COG4221	oxidoreductase activity
A8C11_RS18470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A8C11_RS18480	COG4608	Belongs to the ABC transporter superfamily
A8C11_RS18485	COG0444	Belongs to the ABC transporter superfamily
A8C11_RS18490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C11_RS18495	COG0601	transmembrane transport
A8C11_RS18500	COG0747	negative chemotaxis
A8C11_RS18525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A8C11_RS18535	COG0668	transmembrane transport
A8C11_RS18540	COG0583	DNA-binding transcription factor activity
A8C11_RS18555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A8C11_RS18565	COG3958	Transketolase
A8C11_RS18570	COG3959	Transketolase, thiamine diphosphate binding domain
A8C11_RS18575	COG2390	Transcriptional regulator
A8C11_RS18580	COG5464	transposase or invertase
A8C11_RS18585	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS18590	COG1129	ABC transporter
A8C11_RS18600	COG1879	ABC-type sugar transport system periplasmic component
A8C11_RS18610	COG4771	TonB-dependent receptor
A8C11_RS18615	COG2382	esterase
A8C11_RS18620	COG3251	PFAM MbtH domain protein
A8C11_RS18625	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A8C11_RS18625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A8C11_RS18630	COG1120	ATPase activity
A8C11_RS18635	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C11_RS18640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C11_RS18650	COG4592	Periplasmic binding protein
A8C11_RS18655	COG1169	isochorismate synthase
A8C11_RS18660	COG1021	2,3-dihydroxybenzoate-AMP ligase
A8C11_RS18665	COG3433	isochorismatase activity
A8C11_RS18665	COG1535	isochorismatase
A8C11_RS18670	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS18680	COG1966	Carbon starvation protein
A8C11_RS18685	COG2879	small protein
A8C11_RS18700	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS18705	COG0371	Dehydrogenase
A8C11_RS18710	COG1129	ABC transporter
A8C11_RS18715	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS18745	COG2271	Major facilitator Superfamily
A8C11_RS18750	COG0483	inositol monophosphate 1-phosphatase activity
A8C11_RS18760	COG0402	S-adenosylhomocysteine deaminase activity
A8C11_RS18770	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A8C11_RS18785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8C11_RS18795	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS18800	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS18805	COG1129	ABC transporter
A8C11_RS18830	COG0436	Aminotransferase
A8C11_RS18835	COG1475	DNA binding
A8C11_RS18840	COG3969	phosphoadenosine phosphosulfate
A8C11_RS18845	COG0583	DNA-binding transcription factor activity
A8C11_RS18850	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A8C11_RS18870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A8C11_RS18875	COG3719	Belongs to the RNase T2 family
A8C11_RS18880	COG3069	C4-dicarboxylate transmembrane transporter activity
A8C11_RS18900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A8C11_RS18905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A8C11_RS18915	COG0583	DNA-binding transcription factor activity
A8C11_RS18930	COG1686	Belongs to the peptidase S11 family
A8C11_RS18935	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A8C11_RS18940	COG0772	Belongs to the SEDS family
A8C11_RS18945	COG0768	penicillin binding
A8C11_RS18955	COG0799	negative regulation of ribosome biogenesis
A8C11_RS18970	COG1466	dna polymerase III delta subunit
A8C11_RS18985	COG2888	peptidyl-tyrosine sulfation
A8C11_RS19005	COG1126	abc transporter atp-binding protein
A8C11_RS19010	COG0765	amino acid transport
A8C11_RS19015	COG0765	amino acid transport
A8C11_RS19040	COG1702	phosphate starvation-inducible protein PhoH
A8C11_RS19050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8C11_RS19090	COG0367	asparagine synthase
A8C11_RS19095	COG0647	UMP catabolic process
A8C11_RS19100	COG1846	Transcriptional regulator
A8C11_RS19100	COG1940	carbohydrate kinase activity
A8C11_RS19105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A8C11_RS19145	COG0735	belongs to the Fur family
A8C11_RS19160	COG0596	Alpha beta hydrolase
A8C11_RS19175	COG0033	Phosphoglucomutase
A8C11_RS19185	COG0745	RESPONSE REGULATOR receiver
A8C11_RS19190	COG2205	protein histidine kinase activity
A8C11_RS19215	COG0415	Belongs to the DNA photolyase family
A8C11_RS19230	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A8C11_RS19235	COG1984	allophanate hydrolase subunit 2
A8C11_RS19275	COG2009	succinate dehydrogenase
A8C11_RS19280	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A8C11_RS19285	COG1053	succinate dehydrogenase
A8C11_RS19290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A8C11_RS19295	COG0567	Dehydrogenase, E1 component
A8C11_RS19300	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8C11_RS19310	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A8C11_RS19320	COG1271	oxidase subunit
A8C11_RS19325	COG1294	oxidase, subunit
A8C11_RS19330	COG4890	Cyd operon protein YbgT
A8C11_RS19335	COG3790	cyd operon protein YbgE
A8C11_RS19340	COG0824	Thioesterase
A8C11_RS19345	COG0811	peptide transport
A8C11_RS19350	COG0848	biopolymer transport protein
A8C11_RS19355	COG3064	Membrane
A8C11_RS19365	COG2885	chlorophyll binding
A8C11_RS19370	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
A8C11_RS19435	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A8C11_RS19440	COG3201	nicotinamide mononucleotide transporter
A8C11_RS19455	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A8C11_RS19465	COG2017	converts alpha-aldose to the beta-anomer
A8C11_RS19475	COG1085	galactose-1-phosphate uridylyltransferase
A8C11_RS19485	COG1119	ATPase activity
A8C11_RS19490	COG2005	Transcriptional regulator
A8C11_RS19490	COG3585	molybdate ion transport
A8C11_RS19500	COG0725	ABC transporter, periplasmic molybdate-binding protein
A8C11_RS19505	COG4149	molybdate abc transporter
A8C11_RS19515	COG0561	phosphatase activity
A8C11_RS19540	COG2200	EAL domain
A8C11_RS19545	COG0789	Transcriptional regulator
A8C11_RS19580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C11_RS19585	COG0589	response to stress
A8C11_RS19595	COG4677	pectinesterase activity
A8C11_RS19630	COG1881	PFAM PEBP family protein
A8C11_RS19635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A8C11_RS19650	COG2226	methyltransferase
A8C11_RS19680	COG0642	Histidine kinase
A8C11_RS19685	COG0745	RESPONSE REGULATOR receiver
A8C11_RS19705	COG0521	Mo-molybdopterin cofactor biosynthetic process
A8C11_RS19715	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A8C11_RS19720	COG0314	molybdopterin synthase activity
A8C11_RS19725	COG0670	Belongs to the BI1 family
A8C11_RS19730	COG0392	lysyltransferase activity
A8C11_RS19735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8C11_RS19740	COG3568	Endonuclease Exonuclease Phosphatase
A8C11_RS19750	COG0842	Transport permease protein
A8C11_RS19755	COG0842	Transport permease protein
A8C11_RS19760	COG1131	(ABC) transporter
A8C11_RS19765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C11_RS19770	COG1309	transcriptional regulator
A8C11_RS19775	COG0583	DNA-binding transcription factor activity
A8C11_RS19785	COG2271	Major facilitator Superfamily
A8C11_RS19790	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS19795	COG3959	Transketolase, thiamine diphosphate binding domain
A8C11_RS19800	COG3958	Transketolase
A8C11_RS19805	COG0513	Belongs to the DEAD box helicase family
A8C11_RS19810	COG1199	ATP-dependent helicase activity
A8C11_RS19815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A8C11_RS19825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A8C11_RS19835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A8C11_RS19845	COG0668	transmembrane transport
A8C11_RS19850	COG1126	abc transporter atp-binding protein
A8C11_RS19855	COG0765	amino acid transport
A8C11_RS19860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C11_RS19880	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A8C11_RS19885	COG2194	sulfuric ester hydrolase activity
A8C11_RS19900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A8C11_RS19905	COG2723	6-phospho-beta-galactosidase activity
A8C11_RS19910	COG2188	Transcriptional regulator
A8C11_RS19915	COG1376	ErfK ybiS ycfS ynhG family protein
A8C11_RS19920	COG2365	Tyrosine phosphatase family
A8C11_RS19925	COG0488	(ABC) transporter
A8C11_RS19940	COG2271	Major facilitator Superfamily
A8C11_RS19945	COG1609	Transcriptional regulator
A8C11_RS19955	COG0561	phosphatase activity
A8C11_RS19960	COG1882	Formate acetyltransferase
A8C11_RS19965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8C11_RS19970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A8C11_RS19975	COG0303	'Molybdopterin
A8C11_RS19990	COG0747	negative chemotaxis
A8C11_RS20010	COG2223	nitrite transmembrane transporter activity
A8C11_RS20020	COG2133	pyrroloquinoline quinone binding
A8C11_RS20025	COG0625	glutathione transferase activity
A8C11_RS20035	COG1686	Belongs to the peptidase S11 family
A8C11_RS20040	COG1349	DNA-binding transcription factor activity
A8C11_RS20045	COG0671	phosphoesterase, PA-phosphatase related
A8C11_RS20050	COG2814	Major facilitator Superfamily
A8C11_RS20055	COG0561	phosphatase activity
A8C11_RS20060	COG0738	Major facilitator superfamily
A8C11_RS20065	COG3226	Transcriptional regulator
A8C11_RS20095	COG0778	Nitroreductase
A8C11_RS20110	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A8C11_RS20115	COG3842	ATPase activity
A8C11_RS20120	COG1176	ABC-type spermidine putrescine transport system, permease component I
A8C11_RS20125	COG1177	transmembrane transport
A8C11_RS20140	COG0745	RESPONSE REGULATOR receiver
A8C11_RS20145	COG5002	protein histidine kinase activity
A8C11_RS20150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C11_RS20155	COG4160	amino acid transport
A8C11_RS20160	COG4215	(ABC) transporter
A8C11_RS20165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C11_RS20170	COG1126	abc transporter atp-binding protein
A8C11_RS20180	COG4251	negative regulation of phosphorylation
A8C11_RS20180	COG3706	GGDEF domain
A8C11_RS20180	COG5001	Diguanylate cyclase
A8C11_RS20180	COG2203	Gaf domain
A8C11_RS20185	COG3023	N-Acetylmuramoyl-L-alanine amidase
A8C11_RS20190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8C11_RS20195	COG0702	epimerase
A8C11_RS20200	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
A8C11_RS20205	COG0028	Belongs to the TPP enzyme family
A8C11_RS20215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8C11_RS20225	COG2431	L-lysine efflux transmembrane transporter activity
A8C11_RS20235	COG3593	DNA synthesis involved in DNA repair
A8C11_RS20240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C11_RS20250	COG1278	Cold shock
A8C11_RS20260	COG0542	response to heat
A8C11_RS20275	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A8C11_RS20280	COG4988	ABC transporter
A8C11_RS20285	COG0492	ferredoxin-NADP+ reductase activity
A8C11_RS20300	COG1178	ABC-type Fe3 transport system permease component
A8C11_RS20300	COG1674	ftsk spoiiie
A8C11_RS20310	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A8C11_RS20320	COG0243	molybdopterin cofactor binding
A8C11_RS20325	COG0437	4 iron, 4 sulfur cluster binding
A8C11_RS20330	COG3302	dmso reductase anchor subunit
A8C11_RS20340	COG0477	Major facilitator Superfamily
A8C11_RS20345	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8C11_RS20350	COG1882	Formate acetyltransferase
A8C11_RS20355	COG2116	formate transmembrane transporter activity
A8C11_RS20360	COG1944	ATP diphosphatase activity
A8C11_RS20365	COG2323	membrane
A8C11_RS20385	COG0539	negative regulation of cytoplasmic translation
A8C11_RS20395	COG2333	competence protein COMEC
A8C11_RS20395	COG0658	competence protein
A8C11_RS20410	COG3214	Protein conserved in bacteria
A8C11_RS20425	COG3173	Aminoglycoside phosphotransferase
A8C11_RS20430	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A8C11_RS20435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A8C11_RS20445	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
A8C11_RS20455	COG2989	Protein conserved in bacteria
A8C11_RS20460	COG3108	Peptidase M15
A8C11_RS20465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C11_RS20470	COG1448	Aminotransferase
A8C11_RS20475	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A8C11_RS20485	COG1522	sequence-specific DNA binding
A8C11_RS20495	COG0814	amino acid
A8C11_RS20505	COG1473	amidohydrolase
A8C11_RS20520	COG0308	aminopeptidase N
A8C11_RS20530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C11_RS20535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C11_RS20540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8C11_RS20545	COG0431	NADPH-dependent FMN reductase
A8C11_RS20560	COG0633	Ferredoxin
A8C11_RS20560	COG3217	Mosc domain protein beta barrel domain protein
A8C11_RS20570	COG0488	(ABC) transporter
A8C11_RS20575	COG2995	paraquat-inducible protein a
A8C11_RS20580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A8C11_RS20580	COG3008	intermembrane lipid transfer
A8C11_RS20585	COG3009	Protein conserved in bacteria
A8C11_RS20590	COG3130	regulation of translation
A8C11_RS20600	COG1067	ATP-dependent peptidase activity
A8C11_RS20620	COG3070	regulator of competence-specific genes
A8C11_RS20625	COG1289	transmembrane transporter activity
A8C11_RS20630	COG3304	Inner membrane component domain
A8C11_RS20635	COG0210	DNA helicase
A8C11_RS20645	COG1832	CoA-binding protein
A8C11_RS20665	COG2274	protein secretion by the type I secretion system
A8C11_RS20670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C11_RS20695	COG1881	PFAM PEBP family protein
A8C11_RS20700	COG2207	Transcriptional regulator
A8C11_RS20715	COG0670	Belongs to the BI1 family
A8C11_RS20730	COG0058	SHG alpha-glucan phosphorylase activity
A8C11_RS20740	COG2200	EAL domain
A8C11_RS20760	COG3706	GGDEF domain
A8C11_RS20765	COG2207	Transcriptional regulator
A8C11_RS20775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C11_RS20780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8C11_RS20785	COG1882	Formate acetyltransferase
A8C11_RS20790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C11_RS20795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C11_RS20800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS20800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS20800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A8C11_RS20805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8C11_RS20810	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS20815	COG4638	Rieske (2fe-2S)
A8C11_RS20820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A8C11_RS20825	COG0473	3-isopropylmalate dehydrogenase activity
A8C11_RS20830	COG0583	DNA-binding transcription factor activity
A8C11_RS20835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A8C11_RS20840	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS20845	COG1396	sequence-specific DNA binding
A8C11_RS20845	COG1917	Cupin 2, conserved barrel domain protein
A8C11_RS20850	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A8C11_RS20855	COG0174	glutamine synthetase
A8C11_RS20860	COG0531	amino acid
A8C11_RS20875	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS20905	COG3729	General stress protein
A8C11_RS20915	COG2233	PERMEase
A8C11_RS20950	COG1309	transcriptional regulator
A8C11_RS20965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A8C11_RS20975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C11_RS20995	COG1702	phosphate starvation-inducible protein PhoH
A8C11_RS21010	COG1335	isochorismatase
A8C11_RS21020	COG0583	DNA-binding transcription factor activity
A8C11_RS21045	COG3381	protein complex oligomerization
A8C11_RS21080	COG5645	(Lipo)protein
A8C11_RS21095	COG1560	Kdo2-lipid A biosynthetic process
A8C11_RS21145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C11_RS21165	COG2814	Major facilitator Superfamily
A8C11_RS21170	COG0583	DNA-binding transcription factor activity
A8C11_RS21175	COG1530	ribonuclease E activity
A8C11_RS21190	COG1399	metal-binding, possibly nucleic acid-binding protein
A8C11_RS21210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A8C11_RS21225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A8C11_RS21230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A8C11_RS21235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A8C11_RS21245	COG0470	DNA polymerase III
A8C11_RS21250	COG0084	hydrolase, TatD family'
A8C11_RS21260	COG0537	adenosine 5'-monophosphoramidase activity
A8C11_RS21265	COG5633	Lipoprotein
A8C11_RS21290	COG1252	NADH dehydrogenase
A8C11_RS21295	COG3134	Outer membrane lipoprotein
A8C11_RS21310	COG1309	transcriptional regulator
A8C11_RS21325	COG1376	ErfK ybiS ycfS ynhG family protein
A8C11_RS21325	COG1388	LysM domain
A8C11_RS21330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A8C11_RS21340	COG4591	ABC-type transport system involved in lipoprotein release permease component
A8C11_RS21350	COG4591	ABC-type transport system involved in lipoprotein release permease component
A8C11_RS21360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A8C11_RS21370	COG2390	Transcriptional regulator
A8C11_RS21385	COG3395	kinase activity
A8C11_RS21400	COG0698	ribose 5-phosphate isomerase
A8C11_RS21405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A8C11_RS21410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A8C11_RS21415	COG0318	PFAM AMP-dependent synthetase and ligase
A8C11_RS21430	COG1177	transmembrane transport
A8C11_RS21450	COG2850	peptidyl-arginine hydroxylation
A8C11_RS21455	COG2205	protein histidine kinase activity
A8C11_RS21475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A8C11_RS21495	COG1187	pseudouridine synthase activity
A8C11_RS21500	COG0538	isocitrate dehydrogenase activity
A8C11_RS21505	COG0640	Transcriptional regulator
A8C11_RS21525	COG3813	Protein conserved in bacteria
A8C11_RS21530	COG1063	alcohol dehydrogenase
A8C11_RS21540	COG3729	General stress protein
A8C11_RS21545	COG3685	Protein conserved in bacteria
A8C11_RS21550	COG3685	Protein conserved in bacteria
A8C11_RS21555	COG3546	catalase activity
A8C11_RS21560	COG1271	oxidase subunit
A8C11_RS21565	COG1294	oxidase, subunit
A8C11_RS21595	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A8C11_RS21600	COG0583	DNA-binding transcription factor activity
A8C11_RS21605	COG3706	GGDEF domain
A8C11_RS21610	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A8C11_RS21630	COG1560	Kdo2-lipid A biosynthetic process
A8C11_RS21640	COG3182	Iron-regulated membrane protein
A8C11_RS21655	COG2199	diguanylate cyclase activity
A8C11_RS21655	COG2203	Gaf domain
A8C11_RS21660	COG3042	response to heat
A8C11_RS21665	COG3189	MarR family transcriptional regulator
A8C11_RS21670	COG1683	Conserved Protein
A8C11_RS21675	COG0504	CTP synthase activity
A8C11_RS21680	COG2807	transmembrane transport
A8C11_RS21685	COG2207	Transcriptional regulator
A8C11_RS21695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A8C11_RS21700	COG0859	PFAM glycosyl transferase family 9
A8C11_RS21710	COG3344	reverse transcriptase
A8C11_RS21725	COG1335	isochorismatase
A8C11_RS21735	COG0494	nUDIX hydrolase
A8C11_RS21760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8C11_RS21770	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
A8C11_RS21775	COG0739	heme binding
A8C11_RS21780	COG1560	Kdo2-lipid A biosynthetic process
A8C11_RS21790	COG1737	Transcriptional regulator
A8C11_RS21800	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A8C11_RS21805	COG0129	dihydroxy-acid dehydratase activity
A8C11_RS21810	COG0800	Aldolase
A8C11_RS21820	COG3141	response to X-ray
A8C11_RS21825	COG2979	Protein of unknown function (DUF533)
A8C11_RS21830	COG1770	oligopeptidase
A8C11_RS21835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8C11_RS21845	COG2372	response to copper ion
A8C11_RS21850	COG1276	copper resistance
A8C11_RS21865	COG2990	Protein conserved in bacteria
A8C11_RS21890	COG3008	intermembrane lipid transfer
A8C11_RS21895	COG2995	paraquat-inducible protein a
A8C11_RS21900	COG1956	GAF domain-containing protein
A8C11_RS21925	COG1414	Transcriptional regulator
A8C11_RS21955	COG0768	penicillin binding
A8C11_RS21960	COG2226	methyltransferase
A8C11_RS21975	COG3716	PTS system mannose fructose sorbose family IID component
A8C11_RS21980	COG3715	PTS system
A8C11_RS21985	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS21985	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C11_RS21990	COG1253	flavin adenine dinucleotide binding
A8C11_RS21995	COG2200	EAL domain
A8C11_RS22005	COG1760	l-serine dehydratase
A8C11_RS22025	COG0251	oxidation-reduction process
A8C11_RS22030	COG1199	ATP-dependent helicase activity
A8C11_RS22050	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A8C11_RS22060	COG2894	cell division
A8C11_RS22080	COG0179	Fumarylacetoacetate (FAA) hydrolase
A8C11_RS22110	COG2719	SpoVR family
A8C11_RS22135	COG1619	proteins homologs of microcin C7 resistance protein MccF
A8C11_RS22145	COG4774	siderophore transport
A8C11_RS22155	COG2308	Evidence 4 Homologs of previously reported genes of
A8C11_RS22200	COG0583	DNA-binding transcription factor activity
A8C11_RS22205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A8C11_RS22220	COG1882	Formate acetyltransferase
A8C11_RS22255	COG0583	DNA-binding transcription factor activity
A8C11_RS22285	COG0583	DNA-binding transcription factor activity
A8C11_RS22300	COG3122	Protein conserved in bacteria
A8C11_RS22325	COG2885	chlorophyll binding
A8C11_RS22355	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A8C11_RS22435	COG0012	GTP binding
A8C11_RS22455	COG0659	secondary active sulfate transmembrane transporter activity
A8C11_RS22485	COG2890	protein-(glutamine-N5) methyltransferase activity
A8C11_RS22505	COG0387	Pfam Sodium calcium exchanger
A8C11_RS22510	COG4572	Cation transport regulator
A8C11_RS22515	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
A8C11_RS22525	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A8C11_RS22530	COG3707	response regulator
A8C11_RS22540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8C11_RS22550	COG1116	anion transmembrane transporter activity
A8C11_RS22560	COG0243	molybdopterin cofactor binding
A8C11_RS22565	COG4932	domain protein
A8C11_RS22570	COG2197	response regulator
A8C11_RS22575	COG3850	Histidine kinase
A8C11_RS22580	COG2223	nitrite transmembrane transporter activity
A8C11_RS22590	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A8C11_RS22595	COG1140	nitrate reductase beta subunit
A8C11_RS22600	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A8C11_RS22605	COG2181	nitrate reductase activity
A8C11_RS22615	COG1522	sequence-specific DNA binding
A8C11_RS22660	COG0788	formyltetrahydrofolate deformylase activity
A8C11_RS22670	COG1752	Esterase of the alpha-beta hydrolase superfamily
A8C11_RS22675	COG0745	RESPONSE REGULATOR receiver
A8C11_RS22680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A8C11_RS22685	COG2916	Histone family protein nucleoid-structuring protein H-NS
A8C11_RS22695	COG1435	thymidine kinase activity
A8C11_RS22700	COG1454	alcohol dehydrogenase
A8C11_RS22700	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS22710	COG2095	MarC family integral membrane protein
A8C11_RS22720	COG4166	transmembrane transport
A8C11_RS22725	COG0601	transmembrane transport
A8C11_RS22730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C11_RS22735	COG0444	Belongs to the ABC transporter superfamily
A8C11_RS22745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8C11_RS22765	COG2353	YceI-like domain
A8C11_RS22775	COG2350	Protein conserved in bacteria
A8C11_RS22785	COG3001	Fructosamine kinase
A8C11_RS22795	COG1105	Belongs to the carbohydrate kinase PfkB family
A8C11_RS22800	COG3137	Salt-induced outer membrane protein
A8C11_RS22835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8C11_RS22835	COG0072	phenylalanine-tRNA ligase activity
A8C11_RS22855	COG0583	DNA-binding transcription factor activity
A8C11_RS22875	COG0386	Belongs to the glutathione peroxidase family
A8C11_RS22885	COG0791	NLP P60 protein
A8C11_RS22895	COG4256	Hemin uptake protein
A8C11_RS22900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A8C11_RS22915	COG0574	Belongs to the PEP-utilizing enzyme family
A8C11_RS22915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A8C11_RS22925	COG0628	permease
A8C11_RS22930	COG0277	FAD linked oxidase domain protein
A8C11_RS22930	COG0247	lactate metabolic process
A8C11_RS22935	COG2050	protein possibly involved in aromatic compounds catabolism
A8C11_RS22940	COG2261	transglycosylase associated protein
A8C11_RS22970	COG1120	ATPase activity
A8C11_RS22975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C11_RS22985	COG0583	DNA-binding transcription factor activity
A8C11_RS23010	COG1304	FMN binding
A8C11_RS23015	COG1309	transcriptional regulator
A8C11_RS23035	COG0316	Belongs to the HesB IscA family
A8C11_RS23040	COG0719	Fe-S assembly protein
A8C11_RS23045	COG0396	ATPase activity
A8C11_RS23050	COG0719	Fe-S assembly protein
A8C11_RS23065	COG1376	ErfK ybiS ycfS ynhG family protein
A8C11_RS23095	COG1309	transcriptional regulator
A8C11_RS23100	COG1082	Xylose isomerase domain protein TIM barrel
A8C11_RS23100	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A8C11_RS23105	COG2271	Major facilitator Superfamily
A8C11_RS23110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A8C11_RS23120	COG1120	ATPase activity
A8C11_RS23125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C11_RS23130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8C11_RS23135	COG1414	Transcriptional regulator
A8C11_RS23170	COG2814	Major facilitator Superfamily
A8C11_RS23190	COG0583	DNA-binding transcription factor activity
A8C11_RS23195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C11_RS23215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C11_RS23220	COG1116	anion transmembrane transporter activity
A8C11_RS23225	COG4774	siderophore transport
A8C11_RS23230	COG1120	ATPase activity
A8C11_RS23235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C11_RS23240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C11_RS23265	COG0765	amino acid transport
A8C11_RS23270	COG1126	abc transporter atp-binding protein
A8C11_RS23300	COG1473	amidohydrolase
A8C11_RS23305	COG3383	formate dehydrogenase (NAD+) activity
A8C11_RS23310	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A8C11_RS23325	COG1175	transmembrane transport
A8C11_RS23355	COG1857	crispr-associated protein
A8C11_RS23365	COG1518	maintenance of DNA repeat elements
A8C11_RS23380	COG3157	Type VI secretion system effector, Hcp
A8C11_RS23410	COG4133	protoheme IX ABC transporter activity
A8C11_RS23415	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8C11_RS23420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8C11_RS23435	COG1138	Cytochrome C-type biogenesis protein
A8C11_RS23440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8C11_RS23445	COG3088	subunit of a heme lyase
A8C11_RS23445	COG4235	cytochrome complex assembly
A8C11_RS23490	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS23500	COG1250	3-hydroxyacyl-CoA dehydrogenase
A8C11_RS23510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A8C11_RS23520	COG0583	DNA-binding transcription factor activity
A8C11_RS23540	COG0277	FAD linked oxidase domain protein
A8C11_RS23545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C11_RS23570	COG0402	S-adenosylhomocysteine deaminase activity
A8C11_RS23615	COG2200	EAL domain
A8C11_RS23660	COG2801	Transposase and inactivated derivatives
A8C11_RS23675	COG2814	Major facilitator Superfamily
A8C11_RS23680	COG1082	Xylose isomerase domain protein TIM barrel
A8C11_RS23690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C11_RS23720	COG4608	Belongs to the ABC transporter superfamily
A8C11_RS23725	COG0444	Belongs to the ABC transporter superfamily
A8C11_RS23750	COG0346	lactoylglutathione lyase activity
A8C11_RS23755	COG1349	DNA-binding transcription factor activity
A8C11_RS23795	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A8C11_RS23815	COG0300	oxidoreductase activity
A8C11_RS23860	COG0307	riboflavin synthase, alpha
A8C11_RS23865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A8C11_RS23870	COG2814	Major facilitator Superfamily
A8C11_RS23875	COG0583	DNA-binding transcription factor activity
A8C11_RS23885	COG2814	Major facilitator Superfamily
A8C11_RS23900	COG0791	NLP P60 protein
A8C11_RS23905	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A8C11_RS23915	COG0346	lactoylglutathione lyase activity
A8C11_RS23920	COG1902	pentaerythritol trinitrate reductase activity
A8C11_RS23925	COG1309	transcriptional regulator
A8C11_RS23930	COG3313	Fe-S protein
A8C11_RS23935	COG4989	oxidoreductase activity
A8C11_RS23940	COG2032	superoxide dismutase activity
A8C11_RS23945	COG1289	transmembrane transporter activity
A8C11_RS23950	COG1566	PFAM secretion protein HlyD family protein
A8C11_RS23980	COG3895	Periplasmic Protein
A8C11_RS23995	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
A8C11_RS24000	COG0625	glutathione transferase activity
A8C11_RS24015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A8C11_RS24025	COG4659	FMN binding
A8C11_RS24060	COG2723	6-phospho-beta-galactosidase activity
A8C11_RS24065	COG0673	inositol 2-dehydrogenase activity
A8C11_RS24075	COG2814	Major facilitator Superfamily
A8C11_RS24095	COG3038	cytochrome b561
A8C11_RS24115	COG0583	DNA-binding transcription factor activity
A8C11_RS24120	COG3485	protocatechuate 3,4-dioxygenase
A8C11_RS24125	COG3485	protocatechuate 3,4-dioxygenase
A8C11_RS24130	COG5383	Protein conserved in bacteria
A8C11_RS24135	COG2272	Belongs to the type-B carboxylesterase lipase family
A8C11_RS24150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C11_RS24155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A8C11_RS24160	COG1275	C4-dicarboxylate transporter malic acid transport protein
A8C11_RS24165	COG0500	methyltransferase
A8C11_RS24175	COG0697	spore germination
A8C11_RS24180	COG2207	Transcriptional regulator
A8C11_RS24180	COG3708	Transcriptional regulator
A8C11_RS24185	COG3135	benzoate transporter
A8C11_RS24190	COG1396	sequence-specific DNA binding
A8C11_RS24200	COG0826	peptidase U32
A8C11_RS24220	COG1294	oxidase, subunit
A8C11_RS24225	COG1271	oxidase subunit
A8C11_RS24230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C11_RS24235	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A8C11_RS24240	COG3842	ATPase activity
A8C11_RS24245	COG1176	ABC-type spermidine putrescine transport system, permease component I
A8C11_RS24250	COG1177	transmembrane transport
A8C11_RS24255	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS24290	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS24300	COG0747	negative chemotaxis
A8C11_RS24310	COG3238	Protein conserved in bacteria
A8C11_RS24315	COG1247	-acetyltransferase
A8C11_RS24325	COG2130	NADP-dependent
A8C11_RS24340	COG3691	Protein conserved in bacteria
A8C11_RS24345	COG1228	amidohydrolase
A8C11_RS24350	COG4772	TonB-dependent receptor
A8C11_RS24375	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A8C11_RS24380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C11_RS24385	COG1473	amidohydrolase
A8C11_RS24390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C11_RS24395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C11_RS24405	COG0765	amino acid transport
A8C11_RS24410	COG1126	abc transporter atp-binding protein
A8C11_RS24420	COG0625	glutathione transferase activity
A8C11_RS24440	COG2211	Major facilitator Superfamily
A8C11_RS24455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A8C11_RS24460	COG3842	ATPase activity
A8C11_RS24465	COG1840	ABC-type Fe3 transport system, periplasmic component
A8C11_RS24470	COG1178	ABC-type Fe3 transport system permease component
A8C11_RS24475	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A8C11_RS24480	COG2181	nitrate reductase activity
A8C11_RS24485	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A8C11_RS24490	COG1140	nitrate reductase beta subunit
A8C11_RS24495	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A8C11_RS24515	COG1414	Transcriptional regulator
A8C11_RS24520	COG4948	Mandelate Racemase Muconate Lactonizing
A8C11_RS24525	COG4829	muconolactone delta-isomerase
A8C11_RS24530	COG3485	protocatechuate 3,4-dioxygenase
A8C11_RS24540	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A8C11_RS24560	COG0243	molybdopterin cofactor binding
A8C11_RS24560	COG3383	formate dehydrogenase (NAD+) activity
A8C11_RS24565	COG0243	molybdopterin cofactor binding
A8C11_RS24565	COG3383	formate dehydrogenase (NAD+) activity
A8C11_RS24570	COG0437	4 iron, 4 sulfur cluster binding
A8C11_RS24575	COG2864	formate dehydrogenase
A8C11_RS24585	COG2326	polyphosphate kinase activity
A8C11_RS24595	COG2814	Major facilitator Superfamily
A8C11_RS24605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C11_RS24615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C11_RS24625	COG0747	negative chemotaxis
A8C11_RS24630	COG1064	alcohol dehydrogenase
A8C11_RS24650	COG0488	(ABC) transporter
A8C11_RS24690	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS24695	COG3729	General stress protein
A8C11_RS24705	COG3685	Protein conserved in bacteria
A8C11_RS24715	COG0366	Alpha amylase catalytic
A8C11_RS24725	COG2323	membrane
A8C11_RS24735	COG3111	PFAM Bacterial OB fold (BOF) protein
A8C11_RS24745	COG1764	response to oxidative stress
A8C11_RS24770	COG3781	membrane
A8C11_RS24775	COG0243	molybdopterin cofactor binding
A8C11_RS24780	COG0583	DNA-binding transcription factor activity
A8C11_RS24785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS24810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS24815	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8C11_RS24820	COG2814	Major facilitator Superfamily
A8C11_RS24825	COG1285	pathogenesis
A8C11_RS24830	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A8C11_RS24850	COG0519	Catalyzes the synthesis of GMP from XMP
A8C11_RS24850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A8C11_RS24890	COG0596	Alpha beta hydrolase
A8C11_RS24900	COG2205	protein histidine kinase activity
A8C11_RS24915	COG0076	glutamate decarboxylase activity
A8C11_RS24920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A8C11_RS24925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8C11_RS24930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C11_RS24935	COG1116	anion transmembrane transporter activity
A8C11_RS24940	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A8C11_RS24950	COG0673	inositol 2-dehydrogenase activity
A8C11_RS24960	COG1609	Transcriptional regulator
A8C11_RS24965	COG3706	GGDEF domain
A8C11_RS24970	COG0402	S-adenosylhomocysteine deaminase activity
A8C11_RS24975	COG1953	Uracil, thiamine, allantoin
A8C11_RS25010	COG0596	Alpha beta hydrolase
A8C11_RS25020	COG2207	Transcriptional regulator
A8C11_RS25045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A8C11_RS25070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A8C11_RS25115	COG0765	amino acid transport
A8C11_RS25125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A8C11_RS25135	COG2070	2-Nitropropane dioxygenase
A8C11_RS25140	COG0583	DNA-binding transcription factor activity
A8C11_RS25150	COG1902	pentaerythritol trinitrate reductase activity
A8C11_RS25155	COG4529	Protein conserved in bacteria
A8C11_RS25160	COG0477	Major facilitator Superfamily
A8C11_RS25190	COG2223	nitrite transmembrane transporter activity
A8C11_RS25200	COG1609	Transcriptional regulator
A8C11_RS25205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS25215	COG3037	sugar-specific permease SgaT UlaA
A8C11_RS25220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A8C11_RS25230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C11_RS25235	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A8C11_RS25235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C11_RS25235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C11_RS25250	COG0583	DNA-binding transcription factor activity
A8C11_RS25255	COG0583	DNA-binding transcription factor activity
A8C11_RS25260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C11_RS25270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A8C11_RS25285	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS25295	COG1609	Transcriptional regulator
A8C11_RS25330	COG1652	LysM domain
A8C11_RS25355	COG0456	acetyltransferase
A8C11_RS25355	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A8C11_RS25365	COG0667	Aldo Keto reductase
A8C11_RS25370	COG0667	Aldo Keto reductase
A8C11_RS25375	COG3386	PFAM SMP-30 Gluconolaconase
A8C11_RS25380	COG0667	Aldo Keto reductase
A8C11_RS25395	COG1473	amidohydrolase
A8C11_RS25410	COG0583	DNA-binding transcription factor activity
A8C11_RS25415	COG0626	cystathionine gamma-synthase activity
A8C11_RS25420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C11_RS25425	COG0814	amino acid
A8C11_RS25430	COG0583	DNA-binding transcription factor activity
A8C11_RS25435	COG1294	oxidase, subunit
A8C11_RS25440	COG1271	oxidase subunit
A8C11_RS25450	COG3118	belongs to the thioredoxin family
A8C11_RS25480	COG0583	DNA-binding transcription factor activity
A8C11_RS25520	COG1929	Belongs to the glycerate kinase type-1 family
A8C11_RS25525	COG3835	regulator
A8C11_RS25535	COG0583	DNA-binding transcription factor activity
A8C11_RS25545	COG2186	Transcriptional regulator
A8C11_RS25550	COG1263	PTS System
A8C11_RS25550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C11_RS25565	COG2814	Major facilitator Superfamily
A8C11_RS25570	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS25570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C11_RS25600	COG2819	hydrolase of the alpha beta superfamily
A8C11_RS25605	COG5001	Diguanylate cyclase
A8C11_RS25605	COG3300	MHYT domain
A8C11_RS25640	COG3188	usher protein
A8C11_RS25655	COG1649	PFAM Uncharacterised BCR, COG1649
A8C11_RS25660	COG3550	peptidyl-serine autophosphorylation
A8C11_RS25665	COG1396	sequence-specific DNA binding
A8C11_RS25670	COG2351	hydroxyisourate hydrolase activity
A8C11_RS25675	COG3648	Uricase
A8C11_RS25675	COG3195	allantoin biosynthetic process
A8C11_RS25680	COG2233	PERMEase
A8C11_RS25710	COG2207	Transcriptional regulator
A8C11_RS25725	COG4628	conserved protein (DUF2132)
A8C11_RS25745	COG2011	ABC-type metal ion transport system permease component
A8C11_RS25750	COG2070	2-Nitropropane dioxygenase
A8C11_RS25760	COG0477	Major facilitator Superfamily
A8C11_RS25825	COG2199	diguanylate cyclase activity
A8C11_RS25840	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS25845	COG0583	DNA-binding transcription factor activity
A8C11_RS25855	COG0039	L-malate dehydrogenase activity
A8C11_RS25860	COG1349	DNA-binding transcription factor activity
A8C11_RS25865	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A8C11_RS25870	COG3395	kinase activity
A8C11_RS25880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A8C11_RS25885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8C11_RS25890	COG2271	Major facilitator Superfamily
A8C11_RS25920	COG4977	sequence-specific DNA binding
A8C11_RS25930	COG0697	spore germination
A8C11_RS25935	COG2814	Major facilitator Superfamily
A8C11_RS25965	COG0683	leucine binding
A8C11_RS25970	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A8C11_RS26005	COG2223	nitrite transmembrane transporter activity
A8C11_RS26010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A8C11_RS26025	COG1349	DNA-binding transcription factor activity
A8C11_RS26030	COG2084	Dehydrogenase
A8C11_RS26035	COG3395	kinase activity
A8C11_RS26040	COG0235	Class ii aldolase
A8C11_RS26045	COG3622	Belongs to the hyi family
A8C11_RS26050	COG2610	gluconate transmembrane transporter activity
A8C11_RS26055	COG2207	Transcriptional regulator
A8C11_RS26055	COG3708	Transcriptional regulator
A8C11_RS26070	COG2200	EAL domain
A8C11_RS26075	COG1546	Belongs to the CinA family
A8C11_RS26080	COG0071	Belongs to the small heat shock protein (HSP20) family
A8C11_RS26095	COG2197	response regulator
A8C11_RS26110	COG2135	peptidase activity
A8C11_RS26115	COG2207	Transcriptional regulator
A8C11_RS26130	COG4221	oxidoreductase activity
A8C11_RS26135	COG1802	Transcriptional regulator
A8C11_RS26140	COG0589	response to stress
A8C11_RS26145	COG0246	Mannitol dehydrogenase
A8C11_RS26150	COG2271	Major facilitator Superfamily
A8C11_RS26165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C11_RS26180	COG0243	molybdopterin cofactor binding
A8C11_RS26185	COG0437	4 iron, 4 sulfur cluster binding
A8C11_RS26190	COG3302	dmso reductase anchor subunit
A8C11_RS26205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A8C11_RS26210	COG1940	carbohydrate kinase activity
A8C11_RS26215	COG0583	DNA-binding transcription factor activity
A8C11_RS26220	COG2814	Major facilitator Superfamily
A8C11_RS26225	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A8C11_RS26245	COG3591	Belongs to the peptidase S1B family
A8C11_RS26265	COG0628	permease
A8C11_RS26295	COG0679	Auxin Efflux Carrier
A8C11_RS26305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A8C11_RS26330	COG3290	protein histidine kinase activity
A8C11_RS26335	COG4565	transcriptional regulatory protein
A8C11_RS26360	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A8C11_RS26360	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A8C11_RS26370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8C11_RS26375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A8C11_RS26385	COG0183	Belongs to the thiolase family
A8C11_RS26390	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A8C11_RS26400	COG1414	Transcriptional regulator
A8C11_RS26405	COG2840	Smr protein MutS2
A8C11_RS26410	COG0583	DNA-binding transcription factor activity
A8C11_RS26420	COG1473	amidohydrolase
A8C11_RS26425	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A8C11_RS26440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8C11_RS26455	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A8C11_RS26460	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A8C11_RS26485	COG0531	amino acid
A8C11_RS26495	COG3136	membrane protein required for alginate biosynthesis
A8C11_RS26500	COG0745	RESPONSE REGULATOR receiver
A8C11_RS26510	COG2205	protein histidine kinase activity
A8C11_RS26520	COG0114	fumarate hydratase activity
A8C11_RS26525	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A8C11_RS26525	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A8C11_RS26530	COG1482	cell wall glycoprotein biosynthetic process
A8C11_RS26535	COG5339	Protein conserved in bacteria
A8C11_RS26540	COG1609	Transcriptional regulator
A8C11_RS26545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C11_RS26545	COG1263	PTS System
A8C11_RS26550	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A8C11_RS26575	COG2391	methyltransferase activity
A8C11_RS26580	COG0425	Belongs to the sulfur carrier protein TusA family
A8C11_RS26585	COG5562	phage envelope protein
A8C11_RS26590	COG0401	homolog of Blt101
A8C11_RS26595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A8C11_RS26600	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS26610	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A8C11_RS26615	COG0477	Major facilitator Superfamily
A8C11_RS26620	COG1113	amino acid transport
A8C11_RS26625	COG2988	succinylglutamate desuccinylase activity
A8C11_RS26630	COG3724	N-succinylarginine dihydrolase activity
A8C11_RS26635	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS26640	COG3138	arginine N-succinyltransferase
A8C11_RS26645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A8C11_RS26655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A8C11_RS26660	COG0667	Aldo Keto reductase
A8C11_RS26665	COG0583	DNA-binding transcription factor activity
A8C11_RS26690	COG4122	O-methyltransferase activity
A8C11_RS26695	COG1643	Atp-dependent helicase
A8C11_RS26710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A8C11_RS26715	COG3327	negative regulation of DNA-templated transcription, initiation
A8C11_RS26720	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A8C11_RS26725	COG0183	Belongs to the thiolase family
A8C11_RS26730	COG2050	protein possibly involved in aromatic compounds catabolism
A8C11_RS26735	COG1250	3-hydroxyacyl-CoA dehydrogenase
A8C11_RS26740	COG1024	Enoyl-CoA hydratase
A8C11_RS26745	COG1024	Enoyl-CoA hydratase
A8C11_RS26750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8C11_RS26755	COG2151	metal-sulfur cluster biosynthetic enzyme
A8C11_RS26760	COG3396	Phenylacetate-CoA oxygenase
A8C11_RS26765	COG3460	Phenylacetate-CoA oxygenase
A8C11_RS26770	COG3396	Phenylacetate-CoA oxygenase
A8C11_RS26775	COG2030	dehydratase
A8C11_RS26775	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS26795	COG1012	belongs to the aldehyde dehydrogenase family
A8C11_RS26800	COG2207	Transcriptional regulator
A8C11_RS26805	COG3784	Protein of unknown function (DUF1318)
A8C11_RS26815	COG2911	Protein conserved in bacteria
A8C11_RS26820	COG0586	Pfam SNARE associated Golgi protein
A8C11_RS26825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A8C11_RS26830	COG3187	Heat shock protein
A8C11_RS26835	COG3042	response to heat
A8C11_RS26840	COG0674	pyruvate-flavodoxin oxidoreductase activity
A8C11_RS26840	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8C11_RS26840	COG1013	pyruvate-flavodoxin oxidoreductase activity
A8C11_RS26840	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A8C11_RS26845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A8C11_RS26855	COG0589	response to stress
A8C11_RS26865	COG0513	Belongs to the DEAD box helicase family
A8C11_RS26875	COG1349	DNA-binding transcription factor activity
A8C11_RS26880	COG0673	inositol 2-dehydrogenase activity
A8C11_RS26900	COG1522	sequence-specific DNA binding
A8C11_RS26910	COG1448	Aminotransferase
A8C11_RS26915	COG2011	ABC-type metal ion transport system permease component
A8C11_RS26925	COG1464	Belongs to the NlpA lipoprotein family
A8C11_RS26930	COG0436	Aminotransferase
A8C11_RS26935	COG0604	alcohol dehydrogenase
A8C11_RS26960	COG0583	DNA-binding transcription factor activity
A8C11_RS26980	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS26985	COG1309	transcriptional regulator
A8C11_RS26990	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS27050	COG2801	Transposase and inactivated derivatives
A8C11_RS27090	COG2885	chlorophyll binding
A8C11_RS27120	COG0693	protein deglycase activity
A8C11_RS27125	COG1078	dGTPase activity
A8C11_RS27130	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS27135	COG0583	DNA-binding transcription factor activity
A8C11_RS27200	COG0784	Response regulator, receiver
A8C11_RS27200	COG2205	protein histidine kinase activity
A8C11_RS27200	COG5002	protein histidine kinase activity
A8C11_RS27205	COG3250	beta-galactosidase activity
A8C11_RS27210	COG0656	L-ascorbic acid biosynthetic process
A8C11_RS27240	COG4166	transmembrane transport
A8C11_RS27250	COG2866	Carboxypeptidase
A8C11_RS27255	COG4948	Mandelate Racemase Muconate Lactonizing
A8C11_RS27260	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A8C11_RS27265	COG3180	Ammonia monooxygenase
A8C11_RS27275	COG1486	melibiose metabolic process
A8C11_RS27280	COG0583	DNA-binding transcription factor activity
A8C11_RS27290	COG3106	COG3106 Predicted ATPase
A8C11_RS27300	COG1983	PspC domain protein
A8C11_RS27310	COG1842	Phage shock protein A
A8C11_RS27315	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A8C11_RS27325	COG1473	amidohydrolase
A8C11_RS27340	COG0702	epimerase
A8C11_RS27355	COG4171	peptide transport system, permease
A8C11_RS27370	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A8C11_RS27380	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A8C11_RS27390	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8C11_RS27390	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8C11_RS27405	COG1349	DNA-binding transcription factor activity
A8C11_RS27420	COG0023	Translation Initiation Factor
A8C11_RS27430	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
A8C11_RS27435	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
A8C11_RS27440	COG0671	phosphoesterase, PA-phosphatase related
A8C11_RS27450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A8C11_RS27485	COG0616	signal peptide processing
A8C11_RS27495	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS27500	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A8C11_RS27525	COG0583	DNA-binding transcription factor activity
A8C11_RS27535	COG0009	L-threonylcarbamoyladenylate synthase
A8C11_RS27545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A8C11_RS27550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A8C11_RS27550	COG0512	Glutamine amidotransferase of anthranilate synthase
A8C11_RS27555	COG0135	phosphoribosylanthranilate isomerase activity
A8C11_RS27555	COG0134	indole-3-glycerol-phosphate synthase activity
A8C11_RS27610	COG4774	siderophore transport
A8C11_RS27620	COG3047	cAMP biosynthetic process
A8C11_RS27625	COG0727	PFAM Uncharacterised protein family (UPF0153)
A8C11_RS27655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8C11_RS27660	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS27665	COG1988	membrane-bound metal-dependent
A8C11_RS27670	COG1823	symporter activity
A8C11_RS27680	COG0753	catalase activity
A8C11_RS27690	COG1486	melibiose metabolic process
A8C11_RS27695	COG1917	Cupin 2, conserved barrel domain protein
A8C11_RS27695	COG2169	Transcriptional regulator
A8C11_RS27700	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8C11_RS27705	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS27715	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C11_RS27720	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8C11_RS27730	COG0322	excinuclease ABC activity
A8C11_RS27735	COG3678	ATP-independent chaperone mediated protein folding
A8C11_RS27750	COG3724	N-succinylarginine dihydrolase activity
A8C11_RS27760	COG3138	arginine N-succinyltransferase
A8C11_RS27770	COG0708	Exodeoxyribonuclease III
A8C11_RS27775	COG0398	Pfam SNARE associated Golgi protein
A8C11_RS27780	COG0398	Pfam SNARE associated Golgi protein
A8C11_RS27785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8C11_RS27790	COG4134	Bacterial extracellular solute-binding protein
A8C11_RS27795	COG4135	transport system, permease component
A8C11_RS27800	COG4136	ATPase activity
A8C11_RS27805	COG2897	thiosulfate sulfurtransferase activity
A8C11_RS27810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A8C11_RS27815	COG0494	nUDIX hydrolase
A8C11_RS27825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A8C11_RS27830	COG3321	synthase
A8C11_RS27830	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS27830	COG0604	alcohol dehydrogenase
A8C11_RS27835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A8C11_RS27840	COG0709	Synthesizes selenophosphate from selenide and ATP
A8C11_RS27850	COG0778	Nitroreductase
A8C11_RS27855	COG0616	signal peptide processing
A8C11_RS27860	COG0252	asparaginase activity
A8C11_RS27865	COG1335	isochorismatase
A8C11_RS27880	COG3139	Protein of unknown function (DUF1315)
A8C11_RS27900	COG0656	L-ascorbic acid biosynthetic process
A8C11_RS27905	COG3713	MltA-interacting MipA family protein
A8C11_RS27910	COG2766	serine protein kinase
A8C11_RS27925	COG0386	Belongs to the glutathione peroxidase family
A8C11_RS27950	COG1028	Short-chain dehydrogenase reductase Sdr
A8C11_RS27955	COG0583	DNA-binding transcription factor activity
A8C11_RS27960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A8C11_RS27965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A8C11_RS27970	COG3344	reverse transcriptase
A8C11_RS28120	COG3772	lysozyme
A8C11_RS28275	COG0582	viral genome integration into host DNA
A8C11_RS28280	COG1801	Protein of unknown function DUF72
A8C11_RS28285	COG3788	relative of glutathione S-transferase, MAPEG superfamily
A8C11_RS28305	COG3102	Protein conserved in bacteria
A8C11_RS28315	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A8C11_RS28340	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C11_RS28350	COG1879	ABC-type sugar transport system periplasmic component
A8C11_RS28355	COG1528	Iron-storage protein
A8C11_RS28365	COG2211	Major facilitator Superfamily
A8C11_RS28375	COG0477	Major facilitator Superfamily
A8C11_RS28390	COG1528	Iron-storage protein
A8C11_RS28400	COG0814	amino acid
A8C11_RS28405	COG3318	Belongs to the UPF0149 family
A8C11_RS28405	COG3012	SEC-C Motif Domain Protein
A8C11_RS28440	COG2197	response regulator
A8C11_RS28450	COG2197	response regulator
A8C11_RS28455	COG1126	abc transporter atp-binding protein
A8C11_RS28460	COG0765	amino acid transport
A8C11_RS28470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C11_RS28475	COG0366	Alpha amylase catalytic
A8C11_RS28505	COG2354	Protein conserved in bacteria
A8C11_RS28510	COG0697	spore germination
A8C11_RS28515	COG3727	T/G mismatch-specific endonuclease activity
A8C11_RS28520	COG0270	DNA (cytosine-5-)-methyltransferase activity
A8C11_RS28525	COG1418	mRNA catabolic process
A8C11_RS28535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane