locus-tag	class	description
D1Y71_RS00020	COG0187	DNA topoisomerase II activity
D1Y71_RS00025	COG0561	phosphatase activity
D1Y71_RS00040	COG2186	Transcriptional regulator
D1Y71_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
D1Y71_RS00050	COG0800	Aldolase
D1Y71_RS00060	COG2271	Major facilitator Superfamily
D1Y71_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
D1Y71_RS00070	COG5645	(Lipo)protein
D1Y71_RS00085	COG3645	SOS response
D1Y71_RS00095	COG2188	Transcriptional regulator
D1Y71_RS00110	COG2149	membrane
D1Y71_RS00130	COG2610	gluconate transmembrane transporter activity
D1Y71_RS00135	COG0583	DNA-binding transcription factor activity
D1Y71_RS00140	COG2814	Major facilitator Superfamily
D1Y71_RS00165	COG0028	Belongs to the TPP enzyme family
D1Y71_RS00170	COG0440	acetolactate synthase activity
D1Y71_RS00175	COG2197	response regulator
D1Y71_RS00185	COG2271	Major facilitator Superfamily
D1Y71_RS00230	COG2188	Transcriptional regulator
D1Y71_RS00265	COG4580	involved in the transport of maltose and maltodextrins
D1Y71_RS00270	COG1447	Phosphotransferase system cellobiose-specific component IIA
D1Y71_RS00275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1Y71_RS00275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1Y71_RS00285	COG1609	Transcriptional regulator
D1Y71_RS00295	COG3384	dioxygenase
D1Y71_RS00300	COG0583	DNA-binding transcription factor activity
D1Y71_RS00305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D1Y71_RS00310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D1Y71_RS00315	COG2828	Protein conserved in bacteria
D1Y71_RS00330	COG0697	spore germination
D1Y71_RS00335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1Y71_RS00335	COG1263	PTS System
D1Y71_RS00345	COG2814	Major facilitator Superfamily
D1Y71_RS00355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D1Y71_RS00390	COG0583	DNA-binding transcription factor activity
D1Y71_RS00415	COG1464	Belongs to the NlpA lipoprotein family
D1Y71_RS00430	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D1Y71_RS00440	COG1064	alcohol dehydrogenase
D1Y71_RS00475	COG2211	Major facilitator Superfamily
D1Y71_RS00480	COG1501	Belongs to the glycosyl hydrolase 31 family
D1Y71_RS00490	COG1486	melibiose metabolic process
D1Y71_RS00495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1Y71_RS00495	COG1263	PTS System
D1Y71_RS00500	COG2982	Protein involved in outer membrane biogenesis
D1Y71_RS00505	COG2233	PERMEase
D1Y71_RS00515	COG0786	glutamate:sodium symporter activity
D1Y71_RS00535	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D1Y71_RS00560	COG3152	Membrane
D1Y71_RS00570	COG1494	fructose-1,6-bisphosphatase
D1Y71_RS00575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D1Y71_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D1Y71_RS00585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D1Y71_RS00605	COG2860	membrane
D1Y71_RS00615	COG2169	Transcriptional regulator
D1Y71_RS00615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D1Y71_RS00620	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D1Y71_RS00625	COG1561	YicC-like family, N-terminal region
D1Y71_RS00645	COG1131	(ABC) transporter
D1Y71_RS00650	COG0842	Transport permease protein
D1Y71_RS00680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D1Y71_RS00715	COG1519	Transferase
D1Y71_RS00720	COG1216	Glycosyl transferase, family 2
D1Y71_RS00725	COG0438	transferase activity, transferring glycosyl groups
D1Y71_RS00735	COG0859	PFAM glycosyl transferase family 9
D1Y71_RS00745	COG1216	Glycosyl transferase, family 2
D1Y71_RS00745	COG1442	glycosyl transferase family 8
D1Y71_RS00750	COG3307	-O-antigen
D1Y71_RS00755	COG0438	transferase activity, transferring glycosyl groups
D1Y71_RS00760	COG0859	PFAM glycosyl transferase family 9
D1Y71_RS00775	COG0156	8-amino-7-oxononanoate synthase activity
D1Y71_RS00785	COG0463	Glycosyl transferase, family 2
D1Y71_RS00790	COG2861	carbohydrate metabolic process
D1Y71_RS00795	COG4942	peptidase
D1Y71_RS00805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D1Y71_RS00810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D1Y71_RS00830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D1Y71_RS00840	COG2186	Transcriptional regulator
D1Y71_RS00860	COG3722	fumarate hydratase activity
D1Y71_RS00885	COG0625	glutathione transferase activity
D1Y71_RS00895	COG3276	selenocysteine insertion sequence binding
D1Y71_RS00900	COG1414	Transcriptional regulator
D1Y71_RS00905	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D1Y71_RS00910	COG3977	Valine--pyruvate aminotransferase
D1Y71_RS00915	COG0366	Alpha amylase catalytic
D1Y71_RS00920	COG2992	FlgJ-related protein
D1Y71_RS00925	COG1609	Transcriptional regulator
D1Y71_RS00925	COG2207	Transcriptional regulator
D1Y71_RS00930	COG4214	carbohydrate transport
D1Y71_RS00940	COG4213	ABC transporter substrate-binding protein
D1Y71_RS00960	COG4682	membrane
D1Y71_RS00965	COG4682	membrane
D1Y71_RS00970	COG3274	enterobacterial common antigen metabolic process
D1Y71_RS01020	COG1278	Cold shock
D1Y71_RS01025	COG2944	sequence-specific DNA binding
D1Y71_RS01030	COG2814	Major facilitator Superfamily
D1Y71_RS01055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D1Y71_RS01065	COG1609	Transcriptional regulator
D1Y71_RS01070	COG2885	chlorophyll binding
D1Y71_RS01075	COG0243	molybdopterin cofactor binding
D1Y71_RS01080	COG0456	acetyltransferase
D1Y71_RS01085	COG2818	Glycosylase
D1Y71_RS01090	COG5571	outer membrane autotransporter
D1Y71_RS01095	COG2223	nitrite transmembrane transporter activity
D1Y71_RS01135	COG0747	negative chemotaxis
D1Y71_RS01140	COG0601	transmembrane transport
D1Y71_RS01145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D1Y71_RS01150	COG0444	Belongs to the ABC transporter superfamily
D1Y71_RS01155	COG4608	Belongs to the ABC transporter superfamily
D1Y71_RS01170	COG2894	cell division
D1Y71_RS01190	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D1Y71_RS01195	COG0457	Tetratricopeptide repeat
D1Y71_RS01195	COG3118	belongs to the thioredoxin family
D1Y71_RS01200	COG2199	diguanylate cyclase activity
D1Y71_RS01200	COG2200	EAL domain
D1Y71_RS01210	COG0612	Peptidase, M16
D1Y71_RS01225	COG2982	Protein involved in outer membrane biogenesis
D1Y71_RS01230	COG0477	Major facilitator Superfamily
D1Y71_RS01235	COG1295	ribonuclease BN
D1Y71_RS01240	COG0583	DNA-binding transcription factor activity
D1Y71_RS01245	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS01250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D1Y71_RS01260	COG1454	alcohol dehydrogenase
D1Y71_RS01270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D1Y71_RS01275	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D1Y71_RS01280	COG0671	phosphoesterase, PA-phosphatase related
D1Y71_RS01300	COG0589	response to stress
D1Y71_RS01310	COG0306	phosphate transporter
D1Y71_RS01315	COG2081	HI0933 family
D1Y71_RS01320	COG2239	Acts as a magnesium transporter
D1Y71_RS01330	COG1124	(ABC) transporter
D1Y71_RS01340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D1Y71_RS01345	COG0601	transmembrane transport
D1Y71_RS01350	COG0747	negative chemotaxis
D1Y71_RS01365	COG3479	Phenolic acid decarboxylase
D1Y71_RS01405	COG0628	permease
D1Y71_RS01410	COG0477	Major facilitator Superfamily
D1Y71_RS01420	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D1Y71_RS01435	COG3714	YhhN family
D1Y71_RS01445	COG3776	membrane
D1Y71_RS01450	COG0742	ribosomal rna small subunit methyltransferase
D1Y71_RS01455	COG0552	protein localization to endoplasmic reticulum
D1Y71_RS01460	COG2884	Cell division ATP-binding protein ftsE
D1Y71_RS01465	COG2177	Part of the ABC transporter FtsEX involved in
D1Y71_RS01480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D1Y71_RS01490	COG0683	leucine binding
D1Y71_RS01495	COG0456	acetyltransferase
D1Y71_RS01505	COG0683	leucine binding
D1Y71_RS01510	COG0559	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS01560	COG0584	glycerophosphoryl diester phosphodiesterase
D1Y71_RS01570	COG0405	Gamma-glutamyltransferase
D1Y71_RS01575	COG1247	-acetyltransferase
D1Y71_RS01585	COG0673	inositol 2-dehydrogenase activity
D1Y71_RS01590	COG1741	Belongs to the pirin family
D1Y71_RS01595	COG1609	Transcriptional regulator
D1Y71_RS01600	COG3265	gluconokinase activity
D1Y71_RS01605	COG2610	gluconate transmembrane transporter activity
D1Y71_RS01615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D1Y71_RS01640	COG0058	SHG alpha-glucan phosphorylase activity
D1Y71_RS01655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D1Y71_RS01670	COG1349	DNA-binding transcription factor activity
D1Y71_RS01685	COG0058	SHG alpha-glucan phosphorylase activity
D1Y71_RS01690	COG1640	4-alpha-glucanotransferase
D1Y71_RS01695	COG2610	gluconate transmembrane transporter activity
D1Y71_RS01705	COG1040	competence protein
D1Y71_RS01730	COG1918	ferrous iron import across plasma membrane
D1Y71_RS01735	COG2183	response to ionizing radiation
D1Y71_RS01740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D1Y71_RS01765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D1Y71_RS01770	COG1011	Hydrolase
D1Y71_RS01780	COG0494	nUDIX hydrolase
D1Y71_RS01785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D1Y71_RS01810	COG4796	Type ii and iii secretion system protein
D1Y71_RS01825	COG3266	domain, Protein
D1Y71_RS01830	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D1Y71_RS01835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D1Y71_RS01860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D1Y71_RS01865	COG0402	S-adenosylhomocysteine deaminase activity
D1Y71_RS01870	COG0738	Major facilitator superfamily
D1Y71_RS01895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D1Y71_RS01900	COG1289	transmembrane transporter activity
D1Y71_RS01910	COG1765	OsmC-like protein
D1Y71_RS01915	COG3954	Phosphoribulokinase
D1Y71_RS01925	COG0429	hydrolase of the alpha beta-hydrolase fold
D1Y71_RS01935	COG0488	(ABC) transporter
D1Y71_RS01950	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
D1Y71_RS01955	COG1047	Peptidyl-prolyl cis-trans
D1Y71_RS01965	COG0545	Peptidyl-prolyl cis-trans isomerase
D1Y71_RS01970	COG2964	Protein conserved in bacteria
D1Y71_RS02025	COG0051	transcription antitermination factor activity, RNA binding
D1Y71_RS02050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D1Y71_RS02065	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D1Y71_RS02130	COG0201	protein transport
D1Y71_RS02155	COG0202	RNA polymerase activity
D1Y71_RS02170	COG0789	Transcriptional regulator
D1Y71_RS02175	COG3036	rescue of stalled ribosome
D1Y71_RS02205	COG0758	DNA mediated transformation
D1Y71_RS02215	COG0551	DNA topoisomerase type I activity
D1Y71_RS02235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D1Y71_RS02270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D1Y71_RS02275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D1Y71_RS02280	COG1309	transcriptional regulator
D1Y71_RS02305	COG4145	pantothenate transmembrane transporter activity
D1Y71_RS02310	COG3924	membrane
D1Y71_RS02315	COG0439	Biotin carboxylase
D1Y71_RS02320	COG0511	ligase activity, forming carbon-carbon bonds
D1Y71_RS02345	COG2199	diguanylate cyclase activity
D1Y71_RS02345	COG2200	EAL domain
D1Y71_RS02350	COG1077	Cell shape determining protein MreB Mrl
D1Y71_RS02355	COG1792	Involved in formation and maintenance of cell shape
D1Y71_RS02360	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D1Y71_RS02370	COG1530	ribonuclease E activity
D1Y71_RS02375	COG3164	Protein of unknown function
D1Y71_RS02380	COG0312	modulator of DNA gyrase
D1Y71_RS02385	COG0583	DNA-binding transcription factor activity
D1Y71_RS02400	COG1289	transmembrane transporter activity
D1Y71_RS02405	COG2732	(Barnase) inhibitor
D1Y71_RS02430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D1Y71_RS02435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D1Y71_RS02440	COG3105	Protein conserved in bacteria
D1Y71_RS02445	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D1Y71_RS02465	COG0625	glutathione transferase activity
D1Y71_RS02470	COG2969	positive regulation of protein catabolic process
D1Y71_RS02480	COG0493	'glutamate synthase
D1Y71_RS02485	COG0067	glutamate synthase
D1Y71_RS02485	COG0069	glutamate synthase activity
D1Y71_RS02485	COG0070	glutamate synthase
D1Y71_RS02490	COG1242	4 iron, 4 sulfur cluster binding
D1Y71_RS02495	COG2271	Major facilitator Superfamily
D1Y71_RS02500	COG1063	alcohol dehydrogenase
D1Y71_RS02505	COG1312	Catalyzes the dehydration of D-mannonate
D1Y71_RS02510	COG2198	Histidine kinase
D1Y71_RS02510	COG5002	protein histidine kinase activity
D1Y71_RS02510	COG0784	Response regulator, receiver
D1Y71_RS02515	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
D1Y71_RS02520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D1Y71_RS02525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1Y71_RS02535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1Y71_RS02540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D1Y71_RS02545	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D1Y71_RS02550	COG1137	ATPase activity
D1Y71_RS02555	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
D1Y71_RS02560	COG3117	lipopolysaccharide transmembrane transporter activity
D1Y71_RS02565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D1Y71_RS02575	COG0530	calcium, potassium:sodium antiporter activity
D1Y71_RS02585	COG1127	ABC transporter
D1Y71_RS02590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D1Y71_RS02595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D1Y71_RS02600	COG2854	intermembrane phospholipid transfer
D1Y71_RS02605	COG3113	response to antibiotic
D1Y71_RS02610	COG5007	Belongs to the BolA IbaG family
D1Y71_RS02620	COG3423	Transcriptional regulator
D1Y71_RS02625	COG0142	geranyltranstransferase activity
D1Y71_RS02640	COG0697	spore germination
D1Y71_RS02650	COG2027	D-alanyl-D-alanine carboxypeptidase
D1Y71_RS02660	COG1534	Rna-binding protein
D1Y71_RS02670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D1Y71_RS02675	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D1Y71_RS02685	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D1Y71_RS02735	COG0195	Participates in both transcription termination and antitermination
D1Y71_RS02785	COG0814	amino acid
D1Y71_RS02810	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D1Y71_RS02855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D1Y71_RS02860	COG0826	peptidase U32
D1Y71_RS02865	COG0826	peptidase U32
D1Y71_RS02870	COG3154	lipid carrier protein
D1Y71_RS02875	COG3153	acetyltransferase
D1Y71_RS02890	COG0693	protein deglycase activity
D1Y71_RS02895	COG0702	epimerase
D1Y71_RS02900	COG0701	Predicted permease
D1Y71_RS02905	COG2823	Periplasmic or secreted lipoprotein
D1Y71_RS02925	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D1Y71_RS02930	COG2721	sulfolactate sulfo-lyase activity
D1Y71_RS02940	COG2271	Major facilitator Superfamily
D1Y71_RS02950	COG2084	Dehydrogenase
D1Y71_RS02955	COG1929	Belongs to the glycerate kinase type-1 family
D1Y71_RS02975	COG1741	Belongs to the pirin family
D1Y71_RS02980	COG0583	DNA-binding transcription factor activity
D1Y71_RS02985	COG3152	Membrane
D1Y71_RS02990	COG0435	Glutathione S-transferase
D1Y71_RS02995	COG2259	Doxx family
D1Y71_RS03005	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
D1Y71_RS03010	COG4575	ribosome binding
D1Y71_RS03015	COG1422	Protein of unknown function (DUF1090)
D1Y71_RS03025	COG0586	Pfam SNARE associated Golgi protein
D1Y71_RS03030	COG2186	Transcriptional regulator
D1Y71_RS03035	COG2271	Major facilitator Superfamily
D1Y71_RS03045	COG2721	sulfolactate sulfo-lyase activity
D1Y71_RS03060	COG0861	Integral membrane protein TerC family
D1Y71_RS03065	COG0673	inositol 2-dehydrogenase activity
D1Y71_RS03070	COG1451	nucleotide metabolic process
D1Y71_RS03090	COG0446	pyridine nucleotide-disulphide oxidoreductase
D1Y71_RS03090	COG1902	pentaerythritol trinitrate reductase activity
D1Y71_RS03140	COG1695	Transcriptional regulator
D1Y71_RS03145	COG2375	cellular response to nickel ion
D1Y71_RS03160	COG1461	Dihydroxyacetone kinase
D1Y71_RS03165	COG2376	Dihydroxyacetone kinase
D1Y71_RS03240	COG3247	response to pH
D1Y71_RS03250	COG0784	Response regulator, receiver
D1Y71_RS03250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1Y71_RS03250	COG2205	protein histidine kinase activity
D1Y71_RS03250	COG2198	Histidine kinase
D1Y71_RS03255	COG2197	response regulator
D1Y71_RS03280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D1Y71_RS03285	COG0358	DNA primase activity
D1Y71_RS03290	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D1Y71_RS03350	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D1Y71_RS03365	COG4991	sh3 domain protein
D1Y71_RS03370	COG3025	triphosphatase activity
D1Y71_RS03390	COG2960	long-chain fatty acid transporting porin activity
D1Y71_RS03405	COG3384	dioxygenase
D1Y71_RS03410	COG0754	glutathionylspermidine amidase activity
D1Y71_RS03425	COG0494	nUDIX hydrolase
D1Y71_RS03430	COG3151	Protein conserved in bacteria
D1Y71_RS03435	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D1Y71_RS03440	COG3150	esterase
D1Y71_RS03450	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D1Y71_RS03455	COG2249	NAD(P)H dehydrogenase (quinone) activity
D1Y71_RS03460	COG0642	Histidine kinase
D1Y71_RS03470	COG3111	PFAM Bacterial OB fold (BOF) protein
D1Y71_RS03475	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D1Y71_RS03480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D1Y71_RS03485	COG0204	Acyl-transferase
D1Y71_RS03490	COG2132	Multicopper oxidase
D1Y71_RS03495	COG1032	radical SAM domain protein
D1Y71_RS03505	COG0656	L-ascorbic acid biosynthetic process
D1Y71_RS03510	COG1979	alcohol dehydrogenase
D1Y71_RS03515	COG2207	Transcriptional regulator
D1Y71_RS03520	COG0586	Pfam SNARE associated Golgi protein
D1Y71_RS03525	COG0626	cystathionine gamma-synthase activity
D1Y71_RS03535	COG0848	biopolymer transport protein
D1Y71_RS03555	COG0625	glutathione transferase activity
D1Y71_RS03565	COG0754	glutathionylspermidine amidase activity
D1Y71_RS03570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D1Y71_RS03590	COG0583	DNA-binding transcription factor activity
D1Y71_RS03595	COG0626	cystathionine gamma-synthase activity
D1Y71_RS03640	COG1811	Na channel or pump
D1Y71_RS03650	COG1982	Orn Lys Arg decarboxylase major
D1Y71_RS03655	COG2211	Major facilitator Superfamily
D1Y71_RS03670	COG1194	a g-specific adenine glycosylase
D1Y71_RS03680	COG3171	Protein conserved in bacteria
D1Y71_RS03690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D1Y71_RS03705	COG0762	integral membrane protein
D1Y71_RS03710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D1Y71_RS03715	COG2805	Type II/IV secretion system protein
D1Y71_RS03740	COG0189	ligase activity
D1Y71_RS03745	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D1Y71_RS03750	COG2356	endonuclease I
D1Y71_RS03760	COG2814	Major facilitator Superfamily
D1Y71_RS03790	COG0501	Belongs to the peptidase M48B family
D1Y71_RS03795	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D1Y71_RS03810	COG0191	fructose-bisphosphate aldolase activity
D1Y71_RS03815	COG0668	transmembrane transport
D1Y71_RS03825	COG2968	Membrane
D1Y71_RS03840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D1Y71_RS03845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D1Y71_RS03865	COG0006	proline dipeptidase activity
D1Y71_RS03870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D1Y71_RS03875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D1Y71_RS03895	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS03900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D1Y71_RS03920	COG2723	6-phospho-beta-galactosidase activity
D1Y71_RS03925	COG1737	Transcriptional regulator
D1Y71_RS03935	COG1272	protein, Hemolysin III
D1Y71_RS03945	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D1Y71_RS03955	COG0716	FMN binding
D1Y71_RS03960	COG4974	Belongs to the 'phage' integrase family
D1Y71_RS03970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D1Y71_RS03990	COG4942	peptidase
D1Y71_RS04000	COG2814	Major facilitator Superfamily
D1Y71_RS04015	COG0667	Aldo Keto reductase
D1Y71_RS04055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D1Y71_RS04060	COG1393	Belongs to the ArsC family
D1Y71_RS04080	COG1538	Outer membrane efflux protein
D1Y71_RS04085	COG1289	transmembrane transporter activity
D1Y71_RS04100	COG3592	Divergent 4Fe-4S mono-cluster
D1Y71_RS04105	COG2388	GCN5-related N-acetyl-transferase
D1Y71_RS04115	COG3539	Fimbrial protein
D1Y71_RS04130	COG0667	Aldo Keto reductase
D1Y71_RS04135	COG0814	amino acid
D1Y71_RS04150	COG0183	Belongs to the thiolase family
D1Y71_RS04160	COG0823	Involved in the tonB-independent uptake of proteins
D1Y71_RS04165	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS04170	COG2814	Major facilitator Superfamily
D1Y71_RS04200	COG3842	ATPase activity
D1Y71_RS04205	COG0395	ABC-type sugar transport system, permease component
D1Y71_RS04210	COG1175	transmembrane transport
D1Y71_RS04215	COG1917	Cupin 2, conserved barrel domain protein
D1Y71_RS04220	COG1794	racemase activity, acting on amino acids and derivatives
D1Y71_RS04225	COG0583	DNA-binding transcription factor activity
D1Y71_RS04235	COG1609	Transcriptional regulator
D1Y71_RS04240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1Y71_RS04245	COG2723	6-phospho-beta-galactosidase activity
D1Y71_RS04250	COG2186	Transcriptional regulator
D1Y71_RS04260	COG1609	Transcriptional regulator
D1Y71_RS04275	COG0667	Aldo Keto reductase
D1Y71_RS04285	COG0861	Integral membrane protein TerC family
D1Y71_RS04320	COG2165	general secretion pathway protein
D1Y71_RS04325	COG4795	General secretion pathway protein
D1Y71_RS04335	COG4967	type IV pilus modification protein PilV
D1Y71_RS04340	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D1Y71_RS04345	COG1025	Belongs to the peptidase M16 family
D1Y71_RS04350	COG1074	ATP-dependent DNA helicase activity
D1Y71_RS04355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D1Y71_RS04365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D1Y71_RS04365	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D1Y71_RS04370	COG0860	N-Acetylmuramoyl-L-alanine amidase
D1Y71_RS04375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D1Y71_RS04405	COG4656	Part of a membrane complex involved in electron transport
D1Y71_RS04410	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS04410	COG1454	alcohol dehydrogenase
D1Y71_RS04440	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
D1Y71_RS04605	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D1Y71_RS04610	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D1Y71_RS04615	COG2166	iron-sulfur cluster assembly
D1Y71_RS04620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D1Y71_RS04630	COG0583	DNA-binding transcription factor activity
D1Y71_RS04635	COG2363	Small membrane protein
D1Y71_RS04645	COG1349	DNA-binding transcription factor activity
D1Y71_RS04665	COG0738	Major facilitator superfamily
D1Y71_RS04670	COG0235	Class ii aldolase
D1Y71_RS04675	COG1454	alcohol dehydrogenase
D1Y71_RS04690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D1Y71_RS04710	COG2011	ABC-type metal ion transport system permease component
D1Y71_RS04715	COG1464	Belongs to the NlpA lipoprotein family
D1Y71_RS04725	COG0477	Major facilitator Superfamily
D1Y71_RS04735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D1Y71_RS04740	COG1760	l-serine dehydratase
D1Y71_RS04745	COG0814	amino acid
D1Y71_RS04750	COG1611	Belongs to the LOG family
D1Y71_RS04765	COG3098	single-species biofilm formation
D1Y71_RS04770	COG0564	pseudouridine synthase activity
D1Y71_RS04775	COG0716	FMN binding
D1Y71_RS04780	COG2271	Major facilitator Superfamily
D1Y71_RS04785	COG4948	Mandelate Racemase Muconate Lactonizing
D1Y71_RS04790	COG4948	Mandelate Racemase Muconate Lactonizing
D1Y71_RS04795	COG1929	Belongs to the glycerate kinase type-1 family
D1Y71_RS04805	COG4999	Histidine kinase
D1Y71_RS04805	COG3437	response regulator, receiver
D1Y71_RS04805	COG3850	Histidine kinase
D1Y71_RS04805	COG2205	protein histidine kinase activity
D1Y71_RS04815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D1Y71_RS04820	COG3956	TIGRFAM MazG family protein
D1Y71_RS04840	COG0602	queuosine metabolic process
D1Y71_RS04845	COG0720	synthase
D1Y71_RS04865	COG2234	aminopeptidase activity
D1Y71_RS04925	COG4942	peptidase
D1Y71_RS04925	COG1388	LysM domain
D1Y71_RS04930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D1Y71_RS04955	COG0163	prenyltransferase activity
D1Y71_RS04960	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D1Y71_RS04990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1Y71_RS04995	COG4558	Periplasmic binding protein
D1Y71_RS05000	COG3720	iron ion transport
D1Y71_RS05020	COG0679	Auxin Efflux Carrier
D1Y71_RS05035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D1Y71_RS05040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D1Y71_RS05045	COG1121	(ABC) transporter
D1Y71_RS05050	COG0803	Belongs to the bacterial solute-binding protein 9 family
D1Y71_RS05055	COG1609	Transcriptional regulator
D1Y71_RS05060	COG1940	carbohydrate kinase activity
D1Y71_RS05065	COG1447	Phosphotransferase system cellobiose-specific component IIA
D1Y71_RS05070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1Y71_RS05075	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1Y71_RS05080	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1Y71_RS05090	COG4580	involved in the transport of maltose and maltodextrins
D1Y71_RS05100	COG2723	6-phospho-beta-galactosidase activity
D1Y71_RS05110	COG0309	Hydrogenase expression formation protein (HypE)
D1Y71_RS05115	COG0409	Hydrogenase expression formation protein
D1Y71_RS05120	COG0298	carbon dioxide binding
D1Y71_RS05125	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D1Y71_RS05145	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D1Y71_RS05150	COG0651	ATP synthesis coupled electron transport
D1Y71_RS05155	COG0650	Formate hydrogenlyase subunit 4
D1Y71_RS05160	COG3261	NADH dehydrogenase
D1Y71_RS05160	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
D1Y71_RS05165	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D1Y71_RS05170	COG3260	NADH ubiquinone oxidoreductase 20
D1Y71_RS05180	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D1Y71_RS05190	COG2723	6-phospho-beta-galactosidase activity
D1Y71_RS05195	COG1263	PTS System
D1Y71_RS05195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1Y71_RS05200	COG1609	Transcriptional regulator
D1Y71_RS05205	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D1Y71_RS05210	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
D1Y71_RS05215	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
D1Y71_RS05245	COG1349	DNA-binding transcription factor activity
D1Y71_RS05250	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1Y71_RS05255	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS05265	COG3732	PTS system glucitol sorbitol-specific
D1Y71_RS05270	COG3730	PTS system glucitol sorbitol-specific
D1Y71_RS05275	COG2951	lytic endotransglycosylase activity
D1Y71_RS05290	COG1121	(ABC) transporter
D1Y71_RS05295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D1Y71_RS05305	COG1546	Belongs to the CinA family
D1Y71_RS05330	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D1Y71_RS05360	COG2823	Periplasmic or secreted lipoprotein
D1Y71_RS05365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D1Y71_RS05370	COG1238	metal cluster binding
D1Y71_RS05390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D1Y71_RS05395	COG2814	Major facilitator Superfamily
D1Y71_RS05400	COG1566	PFAM secretion protein HlyD family protein
D1Y71_RS05405	COG1846	Transcriptional regulator
D1Y71_RS05415	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D1Y71_RS05425	COG4176	ABC-type proline glycine betaine transport system permease component
D1Y71_RS05440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D1Y71_RS05450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D1Y71_RS05455	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D1Y71_RS05460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D1Y71_RS05465	COG4575	ribosome binding
D1Y71_RS05490	COG2916	Histone family protein nucleoid-structuring protein H-NS
D1Y71_RS05505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D1Y71_RS05510	COG0640	Transcriptional regulator
D1Y71_RS05520	COG0583	DNA-binding transcription factor activity
D1Y71_RS05525	COG3284	Transcriptional regulator
D1Y71_RS05535	COG3539	Fimbrial protein
D1Y71_RS05540	COG3121	Chaperone
D1Y71_RS05560	COG3188	usher protein
D1Y71_RS05570	COG3539	Fimbrial protein
D1Y71_RS05575	COG2197	response regulator
D1Y71_RS05590	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS05600	COG0235	Class ii aldolase
D1Y71_RS05610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1Y71_RS05645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D1Y71_RS05650	COG2207	Transcriptional regulator
D1Y71_RS05650	COG3708	Transcriptional regulator
D1Y71_RS05725	COG0582	viral genome integration into host DNA
D1Y71_RS05740	COG2867	negative regulation of translational initiation
D1Y71_RS05755	COG0497	DNA recombination
D1Y71_RS05770	COG4536	flavin adenine dinucleotide binding
D1Y71_RS05775	COG4137	Cytochrome C assembly protein
D1Y71_RS05780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D1Y71_RS05815	COG2885	chlorophyll binding
D1Y71_RS05820	COG2199	diguanylate cyclase activity
D1Y71_RS05830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D1Y71_RS05835	COG0287	Prephenate dehydrogenase
D1Y71_RS05835	COG1605	Chorismate mutase
D1Y71_RS05845	COG1605	Chorismate mutase
D1Y71_RS05845	COG0077	Prephenate dehydratase
D1Y71_RS05855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D1Y71_RS05860	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D1Y71_RS05875	COG0542	response to heat
D1Y71_RS05900	COG0477	Major facilitator Superfamily
D1Y71_RS05905	COG5544	Lipoprotein
D1Y71_RS05910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D1Y71_RS05920	COG3148	PFAM DTW domain containing protein
D1Y71_RS05925	COG3118	belongs to the thioredoxin family
D1Y71_RS05930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D1Y71_RS05945	COG0513	Belongs to the DEAD box helicase family
D1Y71_RS05955	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D1Y71_RS05970	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
D1Y71_RS05975	COG3026	antisigma factor binding
D1Y71_RS05980	COG3086	response to oxidative stress
D1Y71_RS05990	COG0681	Belongs to the peptidase S26 family
D1Y71_RS06010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D1Y71_RS06020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D1Y71_RS06025	COG1737	Transcriptional regulator
D1Y71_RS06030	COG0560	Phosphoserine phosphatase
D1Y71_RS06045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D1Y71_RS06045	COG0047	phosphoribosylformylglycinamidine synthase activity
D1Y71_RS06050	COG2205	protein histidine kinase activity
D1Y71_RS06055	COG3170	Tfp pilus assembly protein FimV
D1Y71_RS06060	COG2204	response regulator
D1Y71_RS06065	COG0347	Belongs to the P(II) protein family
D1Y71_RS06070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D1Y71_RS06070	COG1017	nitric oxide dioxygenase activity
D1Y71_RS06080	COG2259	Doxx family
D1Y71_RS06085	COG1940	carbohydrate kinase activity
D1Y71_RS06090	COG0457	Tetratricopeptide repeat
D1Y71_RS06095	COG0477	Major facilitator Superfamily
D1Y71_RS06095	COG2814	Major facilitator Superfamily
D1Y71_RS06100	COG2017	converts alpha-aldose to the beta-anomer
D1Y71_RS06105	COG2814	Major facilitator Superfamily
D1Y71_RS06110	COG3711	transcriptional antiterminator
D1Y71_RS06115	COG3683	transport system, periplasmic component
D1Y71_RS06120	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
D1Y71_RS06150	COG0822	iron-sulfur transferase activity
D1Y71_RS06170	COG0633	Ferredoxin
D1Y71_RS06175	COG2975	iron-sulfur cluster assembly
D1Y71_RS06195	COG2897	thiosulfate sulfurtransferase activity
D1Y71_RS06200	COG2373	Large extracellular alpha-helical protein
D1Y71_RS06205	COG4953	penicillin-binding protein 1C
D1Y71_RS06240	COG2976	Protein conserved in bacteria
D1Y71_RS06260	COG1645	bacterial-type flagellum-dependent swarming motility
D1Y71_RS06270	COG0517	IMP dehydrogenase activity
D1Y71_RS06270	COG0516	GMP reductase activity
D1Y71_RS06280	COG3119	arylsulfatase activity
D1Y71_RS06285	COG0641	radical SAM
D1Y71_RS06320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D1Y71_RS06335	COG2723	6-phospho-beta-galactosidase activity
D1Y71_RS06345	COG2233	PERMEase
D1Y71_RS06360	COG1393	Belongs to the ArsC family
D1Y71_RS06365	COG4783	chaperone-mediated protein folding
D1Y71_RS06370	COG0628	permease
D1Y71_RS06375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1Y71_RS06380	COG2716	regulation of RNA biosynthetic process
D1Y71_RS06390	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
D1Y71_RS06400	COG2321	neutral zinc metallopeptidase
D1Y71_RS06405	COG1444	tRNA N-acetyltransferase activity
D1Y71_RS06410	COG0400	carboxylic ester hydrolase activity
D1Y71_RS06425	COG1393	Belongs to the ArsC family
D1Y71_RS06435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D1Y71_RS06445	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D1Y71_RS06445	COG0493	'glutamate synthase
D1Y71_RS06455	COG5342	invasion associated locus B
D1Y71_RS06460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D1Y71_RS06465	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D1Y71_RS06475	COG4810	utilization protein
D1Y71_RS06555	COG0860	N-Acetylmuramoyl-L-alanine amidase
D1Y71_RS06575	COG2837	iron assimilation
D1Y71_RS06585	COG4150	thiosulfate binding
D1Y71_RS06590	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D1Y71_RS06595	COG4208	sulfate ABC transporter
D1Y71_RS06600	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D1Y71_RS06610	COG4319	ketosteroid isomerase
D1Y71_RS06645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D1Y71_RS06665	COG3530	Putative quorum-sensing-regulated virulence factor
D1Y71_RS06670	COG0385	Bile acid
D1Y71_RS06675	COG0583	DNA-binding transcription factor activity
D1Y71_RS06710	COG3415	Transposase
D1Y71_RS06715	COG3415	Transposase
D1Y71_RS06745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D1Y71_RS06760	COG0667	Aldo Keto reductase
D1Y71_RS06765	COG3961	Belongs to the TPP enzyme family
D1Y71_RS06780	COG3279	Response regulator of the LytR AlgR family
D1Y71_RS06785	COG3275	phosphorelay sensor kinase activity
D1Y71_RS06795	COG0436	Aminotransferase
D1Y71_RS06805	COG2807	transmembrane transport
D1Y71_RS06810	COG0590	tRNA wobble adenosine to inosine editing
D1Y71_RS06815	COG0583	DNA-binding transcription factor activity
D1Y71_RS06910	COG2116	formate transmembrane transporter activity
D1Y71_RS06915	COG2853	Lipoprotein
D1Y71_RS06925	COG3691	Protein conserved in bacteria
D1Y71_RS06940	COG2062	phosphohistidine phosphatase, SixA
D1Y71_RS06965	COG0730	response to heat
D1Y71_RS06970	COG3101	peptidyl-lysine hydroxylation
D1Y71_RS06985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D1Y71_RS07005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D1Y71_RS07015	COG0586	Pfam SNARE associated Golgi protein
D1Y71_RS07025	COG0285	dihydrofolate synthase activity
D1Y71_RS07030	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
D1Y71_RS07035	COG1286	toxin biosynthetic process
D1Y71_RS07040	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D1Y71_RS07045	COG0163	prenyltransferase activity
D1Y71_RS07065	COG4160	amino acid transport
D1Y71_RS07070	COG4598	ABC transporter
D1Y71_RS07080	COG1090	epimerase
D1Y71_RS07085	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D1Y71_RS07090	COG0625	glutathione transferase activity
D1Y71_RS07095	COG0625	glutathione transferase activity
D1Y71_RS07100	COG0622	Phosphoesterase
D1Y71_RS07105	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
D1Y71_RS07110	COG0280	phosphate acetyltransferase
D1Y71_RS07110	COG0857	belongs to the CobB CobQ family
D1Y71_RS07130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D1Y71_RS07135	COG0490	domain, Protein
D1Y71_RS07135	COG0471	metal ion transport
D1Y71_RS07145	COG0436	Aminotransferase
D1Y71_RS07150	COG0583	DNA-binding transcription factor activity
D1Y71_RS07200	COG0839	Belongs to the complex I subunit 6 family
D1Y71_RS07210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D1Y71_RS07215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D1Y71_RS07230	COG2153	protein acetylation
D1Y71_RS07235	COG1169	isochorismate synthase
D1Y71_RS07260	COG0318	PFAM AMP-dependent synthetase and ligase
D1Y71_RS07270	COG5464	transposase or invertase
D1Y71_RS07290	COG1414	Transcriptional regulator
D1Y71_RS07300	COG2271	Major facilitator Superfamily
D1Y71_RS07310	COG0247	lactate metabolic process
D1Y71_RS07320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D1Y71_RS07325	COG2271	Major facilitator Superfamily
D1Y71_RS07330	COG0584	glycerophosphoryl diester phosphodiesterase
D1Y71_RS07340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D1Y71_RS07365	COG0784	Response regulator, receiver
D1Y71_RS07365	COG2205	protein histidine kinase activity
D1Y71_RS07375	COG0642	Histidine kinase
D1Y71_RS07375	COG2198	Histidine kinase
D1Y71_RS07390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D1Y71_RS07390	COG2169	Transcriptional regulator
D1Y71_RS07395	COG3145	DNA-N1-methyladenine dioxygenase activity
D1Y71_RS07400	COG4615	Cyclic peptide transporter
D1Y71_RS07405	COG2239	Acts as a magnesium transporter
D1Y71_RS07410	COG0659	secondary active sulfate transmembrane transporter activity
D1Y71_RS07425	COG0628	permease
D1Y71_RS07450	COG1349	DNA-binding transcription factor activity
D1Y71_RS07455	COG0494	nUDIX hydrolase
D1Y71_RS07475	COG1061	Type III restriction enzyme res subunit
D1Y71_RS07480	COG1187	pseudouridine synthase activity
D1Y71_RS07485	COG2814	Major facilitator Superfamily
D1Y71_RS07495	COG4172	Belongs to the ABC transporter superfamily
D1Y71_RS07500	COG4239	(ABC) transporter, permease
D1Y71_RS07505	COG4174	ABC transporter (Permease)
D1Y71_RS07510	COG4166	transmembrane transport
D1Y71_RS07515	COG2200	EAL domain
D1Y71_RS07520	COG0791	NLP P60 protein
D1Y71_RS07525	COG0671	phosphoesterase, PA-phosphatase related
D1Y71_RS07530	COG0523	cobalamin synthesis protein
D1Y71_RS07535	COG0246	Mannitol dehydrogenase
D1Y71_RS07540	COG1312	Catalyzes the dehydration of D-mannonate
D1Y71_RS07555	COG2814	Major facilitator Superfamily
D1Y71_RS07565	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1Y71_RS07565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1Y71_RS07570	COG1105	Belongs to the carbohydrate kinase PfkB family
D1Y71_RS07575	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
D1Y71_RS07575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D1Y71_RS07575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D1Y71_RS07585	COG2855	membrane
D1Y71_RS07595	COG0583	DNA-binding transcription factor activity
D1Y71_RS07600	COG0833	amino acid
D1Y71_RS07615	COG4771	TonB-dependent receptor
D1Y71_RS07630	COG2311	Membrane
D1Y71_RS07645	COG1129	ABC transporter
D1Y71_RS07655	COG2949	membrane
D1Y71_RS07665	COG1346	cytolysis
D1Y71_RS07675	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D1Y71_RS07680	COG3659	wide pore channel activity
D1Y71_RS07695	COG2723	6-phospho-beta-galactosidase activity
D1Y71_RS07700	COG1538	Outer membrane efflux protein
D1Y71_RS07705	COG0586	Pfam SNARE associated Golgi protein
D1Y71_RS07715	COG1686	Belongs to the peptidase S11 family
D1Y71_RS07730	COG0277	FAD linked oxidase domain protein
D1Y71_RS07735	COG1472	Belongs to the glycosyl hydrolase 3 family
D1Y71_RS07740	COG1732	Glycine betaine
D1Y71_RS07745	COG1174	glycine betaine transport
D1Y71_RS07750	COG1125	glycine betaine transport
D1Y71_RS07755	COG1174	glycine betaine transport
D1Y71_RS07765	COG3275	phosphorelay sensor kinase activity
D1Y71_RS07775	COG4807	Protein conserved in bacteria
D1Y71_RS07795	COG5455	response to cobalt ion
D1Y71_RS07800	COG0583	DNA-binding transcription factor activity
D1Y71_RS07805	COG2252	PERMEase
D1Y71_RS07815	COG0583	DNA-binding transcription factor activity
D1Y71_RS07835	COG0351	phosphomethylpyrimidine kinase
D1Y71_RS07840	COG1830	Aldolase
D1Y71_RS07875	COG1070	Carbohydrate kinase
D1Y71_RS07885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D1Y71_RS07890	COG4948	Mandelate Racemase Muconate Lactonizing
D1Y71_RS07895	COG0747	negative chemotaxis
D1Y71_RS07900	COG0601	transmembrane transport
D1Y71_RS07905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D1Y71_RS07910	COG0444	Belongs to the ABC transporter superfamily
D1Y71_RS07915	COG4608	Belongs to the ABC transporter superfamily
D1Y71_RS07925	COG4974	Belongs to the 'phage' integrase family
D1Y71_RS07975	COG4695	Portal protein
D1Y71_RS08120	COG0826	peptidase U32
D1Y71_RS08125	COG0745	RESPONSE REGULATOR receiver
D1Y71_RS08130	COG2205	protein histidine kinase activity
D1Y71_RS08155	COG1301	dicarboxylic acid transport
D1Y71_RS08170	COG5002	protein histidine kinase activity
D1Y71_RS08175	COG0443	Heat shock 70 kDa protein
D1Y71_RS08180	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D1Y71_RS08195	COG2982	Protein involved in outer membrane biogenesis
D1Y71_RS08200	COG1253	flavin adenine dinucleotide binding
D1Y71_RS08245	COG1088	dTDP-glucose 4,6-dehydratase activity
D1Y71_RS08265	COG0110	maltose O-acetyltransferase activity
D1Y71_RS08270	COG2244	polysaccharide biosynthetic process
D1Y71_RS08365	COG4372	Transposase
D1Y71_RS08370	COG3436	PFAM IS66 Orf2 family protein
D1Y71_RS08395	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D1Y71_RS08425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D1Y71_RS08430	COG0583	DNA-binding transcription factor activity
D1Y71_RS08440	COG0531	amino acid
D1Y71_RS08445	COG0640	Transcriptional regulator
D1Y71_RS08450	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D1Y71_RS08455	COG2925	Exonuclease
D1Y71_RS08470	COG1289	transmembrane transporter activity
D1Y71_RS08490	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
D1Y71_RS08500	COG1942	4-Oxalocrotonate Tautomerase
D1Y71_RS08505	COG0583	DNA-binding transcription factor activity
D1Y71_RS08510	COG0095	Lipoate-protein ligase
D1Y71_RS08515	COG0477	Major facilitator Superfamily
D1Y71_RS08530	COG5001	Diguanylate cyclase
D1Y71_RS08530	COG3300	MHYT domain
D1Y71_RS08535	COG3615	Tellurite resistance protein tehB
D1Y71_RS08600	COG1737	Transcriptional regulator
D1Y71_RS08615	COG0582	viral genome integration into host DNA
D1Y71_RS08625	COG0534	Mate efflux family protein
D1Y71_RS08635	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D1Y71_RS08655	COG0604	alcohol dehydrogenase
D1Y71_RS08660	COG1309	transcriptional regulator
D1Y71_RS08665	COG0025	NhaP-type Na H and K H
D1Y71_RS08790	COG1846	Transcriptional regulator
D1Y71_RS08800	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D1Y71_RS08805	COG1403	HNH endonuclease
D1Y71_RS08880	COG0740	serine-type endopeptidase activity
D1Y71_RS08920	COG1196	nuclear chromosome segregation
D1Y71_RS08970	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D1Y71_RS08985	COG1418	mRNA catabolic process
D1Y71_RS08990	COG0270	DNA (cytosine-5-)-methyltransferase activity
D1Y71_RS08995	COG3727	T/G mismatch-specific endonuclease activity
D1Y71_RS09000	COG0697	spore germination
D1Y71_RS09005	COG2354	Protein conserved in bacteria
D1Y71_RS09035	COG0366	Alpha amylase catalytic
D1Y71_RS09040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1Y71_RS09050	COG0765	amino acid transport
D1Y71_RS09055	COG1126	abc transporter atp-binding protein
D1Y71_RS09060	COG2197	response regulator
D1Y71_RS09070	COG2197	response regulator
D1Y71_RS09110	COG3012	SEC-C Motif Domain Protein
D1Y71_RS09110	COG3318	Belongs to the UPF0149 family
D1Y71_RS09115	COG0814	amino acid
D1Y71_RS09125	COG1528	Iron-storage protein
D1Y71_RS09140	COG0477	Major facilitator Superfamily
D1Y71_RS09150	COG2211	Major facilitator Superfamily
D1Y71_RS09160	COG1528	Iron-storage protein
D1Y71_RS09170	COG1879	ABC-type sugar transport system periplasmic component
D1Y71_RS09180	COG1172	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS09205	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D1Y71_RS09215	COG3102	Protein conserved in bacteria
D1Y71_RS09235	COG3788	relative of glutathione S-transferase, MAPEG superfamily
D1Y71_RS09240	COG1801	Protein of unknown function DUF72
D1Y71_RS09245	COG1335	isochorismatase
D1Y71_RS09255	COG0494	nUDIX hydrolase
D1Y71_RS09280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D1Y71_RS09290	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
D1Y71_RS09295	COG0739	heme binding
D1Y71_RS09300	COG1560	Kdo2-lipid A biosynthetic process
D1Y71_RS09310	COG1737	Transcriptional regulator
D1Y71_RS09325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D1Y71_RS09330	COG0129	dihydroxy-acid dehydratase activity
D1Y71_RS09335	COG0800	Aldolase
D1Y71_RS09345	COG3141	response to X-ray
D1Y71_RS09350	COG2979	Protein of unknown function (DUF533)
D1Y71_RS09355	COG1770	oligopeptidase
D1Y71_RS09360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D1Y71_RS09370	COG2372	response to copper ion
D1Y71_RS09375	COG1276	copper resistance
D1Y71_RS09390	COG2990	Protein conserved in bacteria
D1Y71_RS09415	COG3008	intermembrane lipid transfer
D1Y71_RS09420	COG2995	paraquat-inducible protein a
D1Y71_RS09425	COG1956	GAF domain-containing protein
D1Y71_RS09445	COG2814	Major facilitator Superfamily
D1Y71_RS09455	COG1414	Transcriptional regulator
D1Y71_RS09495	COG0768	penicillin binding
D1Y71_RS09500	COG2226	methyltransferase
D1Y71_RS09515	COG3716	PTS system mannose fructose sorbose family IID component
D1Y71_RS09520	COG3715	PTS system
D1Y71_RS09525	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1Y71_RS09525	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1Y71_RS09530	COG1253	flavin adenine dinucleotide binding
D1Y71_RS09535	COG2200	EAL domain
D1Y71_RS09540	COG1760	l-serine dehydratase
D1Y71_RS09560	COG0251	oxidation-reduction process
D1Y71_RS09565	COG1199	ATP-dependent helicase activity
D1Y71_RS09575	COG3065	identical protein binding
D1Y71_RS09585	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
D1Y71_RS09595	COG2894	cell division
D1Y71_RS09610	COG0179	Fumarylacetoacetate (FAA) hydrolase
D1Y71_RS09640	COG2719	SpoVR family
D1Y71_RS09660	COG1619	proteins homologs of microcin C7 resistance protein MccF
D1Y71_RS09670	COG4774	siderophore transport
D1Y71_RS09685	COG2308	Evidence 4 Homologs of previously reported genes of
D1Y71_RS09725	COG0583	DNA-binding transcription factor activity
D1Y71_RS09730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D1Y71_RS09775	COG0583	DNA-binding transcription factor activity
D1Y71_RS09805	COG0583	DNA-binding transcription factor activity
D1Y71_RS09820	COG3122	Protein conserved in bacteria
D1Y71_RS09845	COG2885	chlorophyll binding
D1Y71_RS09855	COG1388	LysM domain
D1Y71_RS09920	COG0012	GTP binding
D1Y71_RS09940	COG0659	secondary active sulfate transmembrane transporter activity
D1Y71_RS09970	COG2890	protein-(glutamine-N5) methyltransferase activity
D1Y71_RS09990	COG0387	Pfam Sodium calcium exchanger
D1Y71_RS09995	COG4572	Cation transport regulator
D1Y71_RS10000	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D1Y71_RS10010	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
D1Y71_RS10015	COG3707	response regulator
D1Y71_RS10020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D1Y71_RS10030	COG1116	anion transmembrane transporter activity
D1Y71_RS10035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D1Y71_RS10035	COG2146	nitrite reductase [NAD(P)H] activity
D1Y71_RS10040	COG0243	molybdopterin cofactor binding
D1Y71_RS10045	COG4932	domain protein
D1Y71_RS10050	COG2197	response regulator
D1Y71_RS10055	COG3850	Histidine kinase
D1Y71_RS10060	COG2223	nitrite transmembrane transporter activity
D1Y71_RS10065	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D1Y71_RS10070	COG1140	nitrate reductase beta subunit
D1Y71_RS10075	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D1Y71_RS10080	COG2181	nitrate reductase activity
D1Y71_RS10090	COG1522	sequence-specific DNA binding
D1Y71_RS10115	COG0788	formyltetrahydrofolate deformylase activity
D1Y71_RS10125	COG1752	Esterase of the alpha-beta hydrolase superfamily
D1Y71_RS10130	COG0745	RESPONSE REGULATOR receiver
D1Y71_RS10135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D1Y71_RS10140	COG2916	Histone family protein nucleoid-structuring protein H-NS
D1Y71_RS10145	COG1435	thymidine kinase activity
D1Y71_RS10150	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS10150	COG1454	alcohol dehydrogenase
D1Y71_RS10160	COG2095	MarC family integral membrane protein
D1Y71_RS10165	COG4166	transmembrane transport
D1Y71_RS10170	COG0601	transmembrane transport
D1Y71_RS10175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D1Y71_RS10180	COG0444	Belongs to the ABC transporter superfamily
D1Y71_RS10190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D1Y71_RS10210	COG2353	YceI-like domain
D1Y71_RS10215	COG2350	Protein conserved in bacteria
D1Y71_RS10225	COG3001	Fructosamine kinase
D1Y71_RS10235	COG1105	Belongs to the carbohydrate kinase PfkB family
D1Y71_RS10240	COG3137	Salt-induced outer membrane protein
D1Y71_RS10285	COG0072	phenylalanine-tRNA ligase activity
D1Y71_RS10285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D1Y71_RS10305	COG0583	DNA-binding transcription factor activity
D1Y71_RS10325	COG0386	Belongs to the glutathione peroxidase family
D1Y71_RS10335	COG0791	NLP P60 protein
D1Y71_RS10345	COG4256	Hemin uptake protein
D1Y71_RS10350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D1Y71_RS10360	COG0574	Belongs to the PEP-utilizing enzyme family
D1Y71_RS10360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D1Y71_RS10370	COG0628	permease
D1Y71_RS10375	COG0247	lactate metabolic process
D1Y71_RS10375	COG0277	FAD linked oxidase domain protein
D1Y71_RS10380	COG2050	protein possibly involved in aromatic compounds catabolism
D1Y71_RS10385	COG2261	transglycosylase associated protein
D1Y71_RS10415	COG1120	ATPase activity
D1Y71_RS10420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1Y71_RS10430	COG0583	DNA-binding transcription factor activity
D1Y71_RS10455	COG1304	FMN binding
D1Y71_RS10470	COG0316	Belongs to the HesB IscA family
D1Y71_RS10475	COG0719	Fe-S assembly protein
D1Y71_RS10480	COG0396	ATPase activity
D1Y71_RS10485	COG0719	Fe-S assembly protein
D1Y71_RS10500	COG1376	ErfK ybiS ycfS ynhG family protein
D1Y71_RS10525	COG1309	transcriptional regulator
D1Y71_RS10530	COG1082	Xylose isomerase domain protein TIM barrel
D1Y71_RS10530	COG3185	4-Hydroxyphenylpyruvate dioxygenase
D1Y71_RS10535	COG2271	Major facilitator Superfamily
D1Y71_RS10540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D1Y71_RS10550	COG1120	ATPase activity
D1Y71_RS10555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1Y71_RS10560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D1Y71_RS10565	COG1414	Transcriptional regulator
D1Y71_RS10600	COG2814	Major facilitator Superfamily
D1Y71_RS10620	COG0583	DNA-binding transcription factor activity
D1Y71_RS10625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D1Y71_RS10645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D1Y71_RS10650	COG1116	anion transmembrane transporter activity
D1Y71_RS10655	COG4774	siderophore transport
D1Y71_RS10660	COG1120	ATPase activity
D1Y71_RS10665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1Y71_RS10670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1Y71_RS10690	COG0765	amino acid transport
D1Y71_RS10695	COG1126	abc transporter atp-binding protein
D1Y71_RS10725	COG1473	amidohydrolase
D1Y71_RS10730	COG3383	formate dehydrogenase (NAD+) activity
D1Y71_RS10735	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D1Y71_RS10750	COG1175	transmembrane transport
D1Y71_RS10780	COG0346	lactoylglutathione lyase activity
D1Y71_RS10785	COG1349	DNA-binding transcription factor activity
D1Y71_RS10815	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D1Y71_RS10835	COG0300	oxidoreductase activity
D1Y71_RS10870	COG3179	chitinase
D1Y71_RS10950	COG0307	riboflavin synthase, alpha
D1Y71_RS10955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D1Y71_RS10960	COG2814	Major facilitator Superfamily
D1Y71_RS10965	COG0583	DNA-binding transcription factor activity
D1Y71_RS10980	COG2814	Major facilitator Superfamily
D1Y71_RS10995	COG0791	NLP P60 protein
D1Y71_RS11000	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D1Y71_RS11010	COG0346	lactoylglutathione lyase activity
D1Y71_RS11015	COG1902	pentaerythritol trinitrate reductase activity
D1Y71_RS11020	COG1309	transcriptional regulator
D1Y71_RS11025	COG3313	Fe-S protein
D1Y71_RS11030	COG4989	oxidoreductase activity
D1Y71_RS11035	COG2032	superoxide dismutase activity
D1Y71_RS11040	COG1289	transmembrane transporter activity
D1Y71_RS11045	COG1566	PFAM secretion protein HlyD family protein
D1Y71_RS11060	COG3706	GGDEF domain
D1Y71_RS11075	COG3895	Periplasmic Protein
D1Y71_RS11090	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
D1Y71_RS11095	COG0625	glutathione transferase activity
D1Y71_RS11110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D1Y71_RS11120	COG4659	FMN binding
D1Y71_RS11155	COG2723	6-phospho-beta-galactosidase activity
D1Y71_RS11165	COG0673	inositol 2-dehydrogenase activity
D1Y71_RS11195	COG3038	cytochrome b561
D1Y71_RS11215	COG0583	DNA-binding transcription factor activity
D1Y71_RS11220	COG3485	protocatechuate 3,4-dioxygenase
D1Y71_RS11225	COG3485	protocatechuate 3,4-dioxygenase
D1Y71_RS11230	COG5383	Protein conserved in bacteria
D1Y71_RS11235	COG2272	Belongs to the type-B carboxylesterase lipase family
D1Y71_RS11250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D1Y71_RS11255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D1Y71_RS11260	COG1275	C4-dicarboxylate transporter malic acid transport protein
D1Y71_RS11265	COG0500	methyltransferase
D1Y71_RS11280	COG2207	Transcriptional regulator
D1Y71_RS11280	COG3708	Transcriptional regulator
D1Y71_RS11285	COG3135	benzoate transporter
D1Y71_RS11290	COG1396	sequence-specific DNA binding
D1Y71_RS11295	COG0826	peptidase U32
D1Y71_RS11315	COG1294	oxidase, subunit
D1Y71_RS11320	COG1271	oxidase subunit
D1Y71_RS11325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D1Y71_RS11330	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D1Y71_RS11335	COG3842	ATPase activity
D1Y71_RS11345	COG1177	transmembrane transport
D1Y71_RS11350	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS11380	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS11385	COG0747	negative chemotaxis
D1Y71_RS11395	COG3238	Protein conserved in bacteria
D1Y71_RS11400	COG1247	-acetyltransferase
D1Y71_RS11410	COG2130	NADP-dependent
D1Y71_RS11425	COG3691	Protein conserved in bacteria
D1Y71_RS11430	COG1228	amidohydrolase
D1Y71_RS11435	COG4772	TonB-dependent receptor
D1Y71_RS11460	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D1Y71_RS11465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D1Y71_RS11470	COG1473	amidohydrolase
D1Y71_RS11475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D1Y71_RS11480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1Y71_RS11495	COG1126	abc transporter atp-binding protein
D1Y71_RS11505	COG0625	glutathione transferase activity
D1Y71_RS11530	COG2211	Major facilitator Superfamily
D1Y71_RS11545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D1Y71_RS11550	COG3842	ATPase activity
D1Y71_RS11555	COG1840	ABC-type Fe3 transport system, periplasmic component
D1Y71_RS11560	COG1178	ABC-type Fe3 transport system permease component
D1Y71_RS11565	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D1Y71_RS11570	COG2181	nitrate reductase activity
D1Y71_RS11575	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D1Y71_RS11580	COG1140	nitrate reductase beta subunit
D1Y71_RS11585	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D1Y71_RS11605	COG1414	Transcriptional regulator
D1Y71_RS11610	COG4948	Mandelate Racemase Muconate Lactonizing
D1Y71_RS11615	COG4829	muconolactone delta-isomerase
D1Y71_RS11620	COG3485	protocatechuate 3,4-dioxygenase
D1Y71_RS11630	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
D1Y71_RS11655	COG0437	4 iron, 4 sulfur cluster binding
D1Y71_RS11660	COG2864	formate dehydrogenase
D1Y71_RS11675	COG2326	polyphosphate kinase activity
D1Y71_RS11685	COG2814	Major facilitator Superfamily
D1Y71_RS11695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D1Y71_RS11705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D1Y71_RS11715	COG0747	negative chemotaxis
D1Y71_RS11720	COG1064	alcohol dehydrogenase
D1Y71_RS11735	COG0488	(ABC) transporter
D1Y71_RS11770	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS11775	COG3729	General stress protein
D1Y71_RS11795	COG3685	Protein conserved in bacteria
D1Y71_RS11805	COG0366	Alpha amylase catalytic
D1Y71_RS11825	COG3111	PFAM Bacterial OB fold (BOF) protein
D1Y71_RS11830	COG1764	response to oxidative stress
D1Y71_RS11855	COG3781	membrane
D1Y71_RS11860	COG0243	molybdopterin cofactor binding
D1Y71_RS11865	COG0583	DNA-binding transcription factor activity
D1Y71_RS11870	COG2814	Major facilitator Superfamily
D1Y71_RS11880	COG1285	pathogenesis
D1Y71_RS11885	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D1Y71_RS11905	COG0519	Catalyzes the synthesis of GMP from XMP
D1Y71_RS11905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D1Y71_RS11945	COG0596	Alpha beta hydrolase
D1Y71_RS11955	COG2205	protein histidine kinase activity
D1Y71_RS11970	COG0076	glutamate decarboxylase activity
D1Y71_RS11975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D1Y71_RS11980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D1Y71_RS11985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D1Y71_RS11990	COG1116	anion transmembrane transporter activity
D1Y71_RS11995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D1Y71_RS12010	COG0673	inositol 2-dehydrogenase activity
D1Y71_RS12020	COG1609	Transcriptional regulator
D1Y71_RS12025	COG3706	GGDEF domain
D1Y71_RS12030	COG0402	S-adenosylhomocysteine deaminase activity
D1Y71_RS12035	COG1953	Uracil, thiamine, allantoin
D1Y71_RS12070	COG0406	alpha-ribazole phosphatase activity
D1Y71_RS12120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D1Y71_RS12190	COG0765	amino acid transport
D1Y71_RS12200	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D1Y71_RS12210	COG2070	2-Nitropropane dioxygenase
D1Y71_RS12215	COG0583	DNA-binding transcription factor activity
D1Y71_RS12225	COG1902	pentaerythritol trinitrate reductase activity
D1Y71_RS12230	COG4529	Protein conserved in bacteria
D1Y71_RS12235	COG0477	Major facilitator Superfamily
D1Y71_RS12280	COG2223	nitrite transmembrane transporter activity
D1Y71_RS12290	COG1609	Transcriptional regulator
D1Y71_RS12295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1Y71_RS12305	COG3037	sugar-specific permease SgaT UlaA
D1Y71_RS12310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D1Y71_RS12320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D1Y71_RS12325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D1Y71_RS12325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D1Y71_RS12325	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
D1Y71_RS12340	COG0583	DNA-binding transcription factor activity
D1Y71_RS12345	COG0583	DNA-binding transcription factor activity
D1Y71_RS12350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D1Y71_RS12360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D1Y71_RS12375	COG1172	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS12385	COG1609	Transcriptional regulator
D1Y71_RS12415	COG1652	LysM domain
D1Y71_RS12440	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D1Y71_RS12440	COG0456	acetyltransferase
D1Y71_RS12450	COG0667	Aldo Keto reductase
D1Y71_RS12455	COG0667	Aldo Keto reductase
D1Y71_RS12460	COG3386	PFAM SMP-30 Gluconolaconase
D1Y71_RS12495	COG4977	sequence-specific DNA binding
D1Y71_RS12515	COG4977	sequence-specific DNA binding
D1Y71_RS12535	COG1349	DNA-binding transcription factor activity
D1Y71_RS12540	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D1Y71_RS12545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D1Y71_RS12595	COG1929	Belongs to the glycerate kinase type-1 family
D1Y71_RS12600	COG3835	regulator
D1Y71_RS12610	COG0583	DNA-binding transcription factor activity
D1Y71_RS12620	COG2186	Transcriptional regulator
D1Y71_RS12625	COG1263	PTS System
D1Y71_RS12625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1Y71_RS12635	COG2814	Major facilitator Superfamily
D1Y71_RS12640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1Y71_RS12640	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1Y71_RS12650	COG2819	hydrolase of the alpha beta superfamily
D1Y71_RS12655	COG3300	MHYT domain
D1Y71_RS12655	COG5001	Diguanylate cyclase
D1Y71_RS12695	COG3188	usher protein
D1Y71_RS12710	COG1649	PFAM Uncharacterised BCR, COG1649
D1Y71_RS12715	COG3550	peptidyl-serine autophosphorylation
D1Y71_RS12720	COG1396	sequence-specific DNA binding
D1Y71_RS12725	COG2351	hydroxyisourate hydrolase activity
D1Y71_RS12730	COG3195	allantoin biosynthetic process
D1Y71_RS12730	COG3648	Uricase
D1Y71_RS12735	COG2233	PERMEase
D1Y71_RS12765	COG2207	Transcriptional regulator
D1Y71_RS12780	COG4628	conserved protein (DUF2132)
D1Y71_RS12800	COG2011	ABC-type metal ion transport system permease component
D1Y71_RS12805	COG2070	2-Nitropropane dioxygenase
D1Y71_RS12815	COG0477	Major facilitator Superfamily
D1Y71_RS12895	COG2199	diguanylate cyclase activity
D1Y71_RS12910	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS12915	COG0583	DNA-binding transcription factor activity
D1Y71_RS12925	COG0039	L-malate dehydrogenase activity
D1Y71_RS12930	COG1349	DNA-binding transcription factor activity
D1Y71_RS12935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D1Y71_RS12940	COG3395	kinase activity
D1Y71_RS12950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D1Y71_RS12965	COG2731	YhcH YjgK YiaL family protein
D1Y71_RS12970	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS12995	COG4977	sequence-specific DNA binding
D1Y71_RS13005	COG0697	spore germination
D1Y71_RS13010	COG2814	Major facilitator Superfamily
D1Y71_RS13025	COG1129	ABC transporter
D1Y71_RS13045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D1Y71_RS13080	COG2223	nitrite transmembrane transporter activity
D1Y71_RS13085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D1Y71_RS13100	COG1349	DNA-binding transcription factor activity
D1Y71_RS13105	COG2084	Dehydrogenase
D1Y71_RS13110	COG3395	kinase activity
D1Y71_RS13115	COG0235	Class ii aldolase
D1Y71_RS13130	COG1546	Belongs to the CinA family
D1Y71_RS13135	COG0071	Belongs to the small heat shock protein (HSP20) family
D1Y71_RS13165	COG2135	peptidase activity
D1Y71_RS13170	COG2207	Transcriptional regulator
D1Y71_RS13185	COG4221	oxidoreductase activity
D1Y71_RS13190	COG1802	Transcriptional regulator
D1Y71_RS13195	COG0589	response to stress
D1Y71_RS13200	COG0246	Mannitol dehydrogenase
D1Y71_RS13205	COG2271	Major facilitator Superfamily
D1Y71_RS13220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D1Y71_RS13235	COG0243	molybdopterin cofactor binding
D1Y71_RS13240	COG0437	4 iron, 4 sulfur cluster binding
D1Y71_RS13245	COG3302	dmso reductase anchor subunit
D1Y71_RS13260	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D1Y71_RS13265	COG1940	carbohydrate kinase activity
D1Y71_RS13270	COG0583	DNA-binding transcription factor activity
D1Y71_RS13275	COG2814	Major facilitator Superfamily
D1Y71_RS13280	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D1Y71_RS13290	COG3591	Belongs to the peptidase S1B family
D1Y71_RS13315	COG0628	permease
D1Y71_RS13345	COG0679	Auxin Efflux Carrier
D1Y71_RS13355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D1Y71_RS13380	COG3290	protein histidine kinase activity
D1Y71_RS13385	COG4565	transcriptional regulatory protein
D1Y71_RS13410	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D1Y71_RS13410	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D1Y71_RS13425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D1Y71_RS13430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D1Y71_RS13440	COG0183	Belongs to the thiolase family
D1Y71_RS13445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D1Y71_RS13455	COG1414	Transcriptional regulator
D1Y71_RS13460	COG2840	Smr protein MutS2
D1Y71_RS13465	COG0583	DNA-binding transcription factor activity
D1Y71_RS13475	COG1473	amidohydrolase
D1Y71_RS13480	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D1Y71_RS13495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D1Y71_RS13510	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
D1Y71_RS13515	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
D1Y71_RS13535	COG0531	amino acid
D1Y71_RS13545	COG3136	membrane protein required for alginate biosynthesis
D1Y71_RS13550	COG0745	RESPONSE REGULATOR receiver
D1Y71_RS13560	COG2205	protein histidine kinase activity
D1Y71_RS13570	COG0114	fumarate hydratase activity
D1Y71_RS13580	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D1Y71_RS13580	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D1Y71_RS13585	COG1482	cell wall glycoprotein biosynthetic process
D1Y71_RS13590	COG5339	Protein conserved in bacteria
D1Y71_RS13595	COG1609	Transcriptional regulator
D1Y71_RS13600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1Y71_RS13600	COG1263	PTS System
D1Y71_RS13605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D1Y71_RS13630	COG2391	methyltransferase activity
D1Y71_RS13635	COG0425	Belongs to the sulfur carrier protein TusA family
D1Y71_RS13640	COG5562	phage envelope protein
D1Y71_RS13645	COG0401	homolog of Blt101
D1Y71_RS13650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D1Y71_RS13655	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS13660	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D1Y71_RS13670	COG1113	amino acid transport
D1Y71_RS13675	COG2988	succinylglutamate desuccinylase activity
D1Y71_RS13680	COG3724	N-succinylarginine dihydrolase activity
D1Y71_RS13685	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS13690	COG3138	arginine N-succinyltransferase
D1Y71_RS13695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D1Y71_RS13700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D1Y71_RS13705	COG0667	Aldo Keto reductase
D1Y71_RS13710	COG0583	DNA-binding transcription factor activity
D1Y71_RS13735	COG4122	O-methyltransferase activity
D1Y71_RS13740	COG1643	Atp-dependent helicase
D1Y71_RS13755	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D1Y71_RS13760	COG3327	negative regulation of DNA-templated transcription, initiation
D1Y71_RS13765	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
D1Y71_RS13770	COG0183	Belongs to the thiolase family
D1Y71_RS13775	COG2050	protein possibly involved in aromatic compounds catabolism
D1Y71_RS13780	COG1250	3-hydroxyacyl-CoA dehydrogenase
D1Y71_RS13785	COG1024	Enoyl-CoA hydratase
D1Y71_RS13790	COG1024	Enoyl-CoA hydratase
D1Y71_RS13795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D1Y71_RS13800	COG2151	metal-sulfur cluster biosynthetic enzyme
D1Y71_RS13805	COG3396	Phenylacetate-CoA oxygenase
D1Y71_RS13810	COG3460	Phenylacetate-CoA oxygenase
D1Y71_RS13815	COG3396	Phenylacetate-CoA oxygenase
D1Y71_RS13820	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS13820	COG2030	dehydratase
D1Y71_RS13845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D1Y71_RS13860	COG2072	flavoprotein involved in K transport
D1Y71_RS13865	COG0583	DNA-binding transcription factor activity
D1Y71_RS13870	COG1126	abc transporter atp-binding protein
D1Y71_RS13880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1Y71_RS13895	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS13900	COG2207	Transcriptional regulator
D1Y71_RS13905	COG3784	Protein of unknown function (DUF1318)
D1Y71_RS13915	COG2911	Protein conserved in bacteria
D1Y71_RS13920	COG0586	Pfam SNARE associated Golgi protein
D1Y71_RS13925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D1Y71_RS13930	COG3187	Heat shock protein
D1Y71_RS13935	COG3042	response to heat
D1Y71_RS13945	COG0674	pyruvate-flavodoxin oxidoreductase activity
D1Y71_RS13945	COG1013	pyruvate-flavodoxin oxidoreductase activity
D1Y71_RS13945	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
D1Y71_RS13945	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D1Y71_RS13950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D1Y71_RS13960	COG0589	response to stress
D1Y71_RS13970	COG0513	Belongs to the DEAD box helicase family
D1Y71_RS13985	COG1349	DNA-binding transcription factor activity
D1Y71_RS13990	COG0673	inositol 2-dehydrogenase activity
D1Y71_RS14005	COG1113	amino acid transport
D1Y71_RS14010	COG1522	sequence-specific DNA binding
D1Y71_RS14020	COG1448	Aminotransferase
D1Y71_RS14025	COG2011	ABC-type metal ion transport system permease component
D1Y71_RS14040	COG0436	Aminotransferase
D1Y71_RS14045	COG0604	alcohol dehydrogenase
D1Y71_RS14070	COG0583	DNA-binding transcription factor activity
D1Y71_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS14095	COG1309	transcriptional regulator
D1Y71_RS14100	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS14150	COG0693	protein deglycase activity
D1Y71_RS14155	COG1078	dGTPase activity
D1Y71_RS14160	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS14165	COG0583	DNA-binding transcription factor activity
D1Y71_RS14185	COG0656	L-ascorbic acid biosynthetic process
D1Y71_RS14265	COG4166	transmembrane transport
D1Y71_RS14270	COG2866	Carboxypeptidase
D1Y71_RS14275	COG4948	Mandelate Racemase Muconate Lactonizing
D1Y71_RS14280	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D1Y71_RS14285	COG3180	Ammonia monooxygenase
D1Y71_RS14295	COG1486	melibiose metabolic process
D1Y71_RS14300	COG0583	DNA-binding transcription factor activity
D1Y71_RS14310	COG3106	COG3106 Predicted ATPase
D1Y71_RS14320	COG1983	PspC domain protein
D1Y71_RS14330	COG1842	Phage shock protein A
D1Y71_RS14335	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D1Y71_RS14345	COG1473	amidohydrolase
D1Y71_RS14360	COG0702	epimerase
D1Y71_RS14375	COG2135	peptidase activity
D1Y71_RS14380	COG0653	protein targeting
D1Y71_RS14385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D1Y71_RS14390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D1Y71_RS14445	COG1196	nuclear chromosome segregation
D1Y71_RS14530	COG5484	DNA packaging
D1Y71_RS14530	COG3728	DNA packaging
D1Y71_RS14590	COG0484	heat shock protein binding
D1Y71_RS14595	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D1Y71_RS14660	COG1484	DNA-dependent DNA replication
D1Y71_RS14715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D1Y71_RS14740	COG4171	peptide transport system, permease
D1Y71_RS14755	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D1Y71_RS14765	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D1Y71_RS14770	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D1Y71_RS14770	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D1Y71_RS14785	COG1349	DNA-binding transcription factor activity
D1Y71_RS14795	COG0023	Translation Initiation Factor
D1Y71_RS14805	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D1Y71_RS14810	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
D1Y71_RS14815	COG0671	phosphoesterase, PA-phosphatase related
D1Y71_RS14825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D1Y71_RS14850	COG0616	signal peptide processing
D1Y71_RS14860	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS14865	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
D1Y71_RS14875	COG0583	DNA-binding transcription factor activity
D1Y71_RS14885	COG0009	L-threonylcarbamoyladenylate synthase
D1Y71_RS14895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D1Y71_RS14900	COG0512	Glutamine amidotransferase of anthranilate synthase
D1Y71_RS14900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D1Y71_RS14905	COG0134	indole-3-glycerol-phosphate synthase activity
D1Y71_RS14905	COG0135	phosphoribosylanthranilate isomerase activity
D1Y71_RS14940	COG4774	siderophore transport
D1Y71_RS14950	COG3047	cAMP biosynthetic process
D1Y71_RS14955	COG0727	PFAM Uncharacterised protein family (UPF0153)
D1Y71_RS14985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D1Y71_RS14990	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS14995	COG1988	membrane-bound metal-dependent
D1Y71_RS15000	COG1823	symporter activity
D1Y71_RS15010	COG0753	catalase activity
D1Y71_RS15020	COG1486	melibiose metabolic process
D1Y71_RS15025	COG1917	Cupin 2, conserved barrel domain protein
D1Y71_RS15025	COG2169	Transcriptional regulator
D1Y71_RS15030	COG1447	Phosphotransferase system cellobiose-specific component IIA
D1Y71_RS15035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1Y71_RS15040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1Y71_RS15045	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D1Y71_RS15055	COG0322	excinuclease ABC activity
D1Y71_RS15060	COG3678	ATP-independent chaperone mediated protein folding
D1Y71_RS15070	COG3724	N-succinylarginine dihydrolase activity
D1Y71_RS15080	COG3138	arginine N-succinyltransferase
D1Y71_RS15090	COG0708	Exodeoxyribonuclease III
D1Y71_RS15095	COG0398	Pfam SNARE associated Golgi protein
D1Y71_RS15100	COG0398	Pfam SNARE associated Golgi protein
D1Y71_RS15105	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D1Y71_RS15110	COG4134	Bacterial extracellular solute-binding protein
D1Y71_RS15115	COG4135	transport system, permease component
D1Y71_RS15120	COG4136	ATPase activity
D1Y71_RS15125	COG2897	thiosulfate sulfurtransferase activity
D1Y71_RS15130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D1Y71_RS15135	COG0494	nUDIX hydrolase
D1Y71_RS15140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D1Y71_RS15145	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS15145	COG3321	synthase
D1Y71_RS15145	COG0604	alcohol dehydrogenase
D1Y71_RS15150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D1Y71_RS15155	COG0709	Synthesizes selenophosphate from selenide and ATP
D1Y71_RS15175	COG0778	Nitroreductase
D1Y71_RS15180	COG0616	signal peptide processing
D1Y71_RS15185	COG0252	asparaginase activity
D1Y71_RS15190	COG1335	isochorismatase
D1Y71_RS15205	COG3139	Protein of unknown function (DUF1315)
D1Y71_RS15225	COG0656	L-ascorbic acid biosynthetic process
D1Y71_RS15230	COG3713	MltA-interacting MipA family protein
D1Y71_RS15235	COG2766	serine protein kinase
D1Y71_RS15250	COG0386	Belongs to the glutathione peroxidase family
D1Y71_RS15270	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS15275	COG0583	DNA-binding transcription factor activity
D1Y71_RS15280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D1Y71_RS15285	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D1Y71_RS15295	COG0859	PFAM glycosyl transferase family 9
D1Y71_RS15300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D1Y71_RS15310	COG2207	Transcriptional regulator
D1Y71_RS15315	COG2807	transmembrane transport
D1Y71_RS15320	COG0504	CTP synthase activity
D1Y71_RS15325	COG1683	Conserved Protein
D1Y71_RS15330	COG3189	MarR family transcriptional regulator
D1Y71_RS15335	COG3042	response to heat
D1Y71_RS15340	COG2199	diguanylate cyclase activity
D1Y71_RS15340	COG2203	Gaf domain
D1Y71_RS15355	COG3182	Iron-regulated membrane protein
D1Y71_RS15365	COG1560	Kdo2-lipid A biosynthetic process
D1Y71_RS15385	COG3706	GGDEF domain
D1Y71_RS15390	COG0583	DNA-binding transcription factor activity
D1Y71_RS15395	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D1Y71_RS15420	COG1294	oxidase, subunit
D1Y71_RS15425	COG1271	oxidase subunit
D1Y71_RS15430	COG3546	catalase activity
D1Y71_RS15435	COG3685	Protein conserved in bacteria
D1Y71_RS15440	COG3685	Protein conserved in bacteria
D1Y71_RS15445	COG3729	General stress protein
D1Y71_RS15460	COG1063	alcohol dehydrogenase
D1Y71_RS15465	COG3813	Protein conserved in bacteria
D1Y71_RS15485	COG0640	Transcriptional regulator
D1Y71_RS15490	COG0538	isocitrate dehydrogenase activity
D1Y71_RS15580	COG0616	signal peptide processing
D1Y71_RS15595	COG4626	Terminase
D1Y71_RS15595	COG1802	Transcriptional regulator
D1Y71_RS15640	COG3772	lysozyme
D1Y71_RS15675	COG1403	HNH endonuclease
D1Y71_RS15750	COG1396	sequence-specific DNA binding
D1Y71_RS15770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D1Y71_RS15780	COG0582	viral genome integration into host DNA
D1Y71_RS15785	COG0538	isocitrate dehydrogenase activity
D1Y71_RS15790	COG1187	pseudouridine synthase activity
D1Y71_RS15810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D1Y71_RS15830	COG2205	protein histidine kinase activity
D1Y71_RS15835	COG2850	peptidyl-arginine hydroxylation
D1Y71_RS15855	COG1177	transmembrane transport
D1Y71_RS15870	COG0318	PFAM AMP-dependent synthetase and ligase
D1Y71_RS15880	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D1Y71_RS15890	COG4591	ABC-type transport system involved in lipoprotein release permease component
D1Y71_RS15900	COG4591	ABC-type transport system involved in lipoprotein release permease component
D1Y71_RS15905	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D1Y71_RS15910	COG1376	ErfK ybiS ycfS ynhG family protein
D1Y71_RS15910	COG1388	LysM domain
D1Y71_RS15920	COG1309	transcriptional regulator
D1Y71_RS15930	COG3134	Outer membrane lipoprotein
D1Y71_RS15935	COG1252	NADH dehydrogenase
D1Y71_RS15960	COG5633	Lipoprotein
D1Y71_RS15965	COG0537	adenosine 5'-monophosphoramidase activity
D1Y71_RS15975	COG0084	hydrolase, TatD family'
D1Y71_RS15980	COG0470	DNA polymerase III
D1Y71_RS15990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D1Y71_RS15995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D1Y71_RS16000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D1Y71_RS16015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D1Y71_RS16035	COG1399	metal-binding, possibly nucleic acid-binding protein
D1Y71_RS16055	COG1530	ribonuclease E activity
D1Y71_RS16060	COG0583	DNA-binding transcription factor activity
D1Y71_RS16065	COG2814	Major facilitator Superfamily
D1Y71_RS16085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D1Y71_RS16135	COG1560	Kdo2-lipid A biosynthetic process
D1Y71_RS16165	COG5645	(Lipo)protein
D1Y71_RS16205	COG3381	protein complex oligomerization
D1Y71_RS16235	COG1309	transcriptional regulator
D1Y71_RS16240	COG0583	DNA-binding transcription factor activity
D1Y71_RS16250	COG1335	isochorismatase
D1Y71_RS16265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D1Y71_RS16270	COG1702	phosphate starvation-inducible protein PhoH
D1Y71_RS16290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D1Y71_RS16300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D1Y71_RS16315	COG1309	transcriptional regulator
D1Y71_RS16350	COG2233	PERMEase
D1Y71_RS16365	COG3729	General stress protein
D1Y71_RS16390	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS16405	COG0531	amino acid
D1Y71_RS16415	COG0174	glutamine synthetase
D1Y71_RS16420	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D1Y71_RS16425	COG1917	Cupin 2, conserved barrel domain protein
D1Y71_RS16425	COG1396	sequence-specific DNA binding
D1Y71_RS16430	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS16435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D1Y71_RS16440	COG0583	DNA-binding transcription factor activity
D1Y71_RS16445	COG0473	3-isopropylmalate dehydrogenase activity
D1Y71_RS16455	COG4638	Rieske (2fe-2S)
D1Y71_RS16460	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS16465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D1Y71_RS16475	COG2200	EAL domain
D1Y71_RS16480	COG2200	EAL domain
D1Y71_RS16495	COG0670	Belongs to the BI1 family
D1Y71_RS16510	COG2207	Transcriptional regulator
D1Y71_RS16515	COG1881	PFAM PEBP family protein
D1Y71_RS16530	COG1832	CoA-binding protein
D1Y71_RS16540	COG0210	DNA helicase
D1Y71_RS16545	COG3304	Inner membrane component domain
D1Y71_RS16550	COG1289	transmembrane transporter activity
D1Y71_RS16555	COG3070	regulator of competence-specific genes
D1Y71_RS16580	COG1067	ATP-dependent peptidase activity
D1Y71_RS16590	COG3130	regulation of translation
D1Y71_RS16595	COG3009	Protein conserved in bacteria
D1Y71_RS16600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D1Y71_RS16600	COG3008	intermembrane lipid transfer
D1Y71_RS16605	COG2995	paraquat-inducible protein a
D1Y71_RS16610	COG0488	(ABC) transporter
D1Y71_RS16620	COG0633	Ferredoxin
D1Y71_RS16620	COG3217	Mosc domain protein beta barrel domain protein
D1Y71_RS16635	COG0431	NADPH-dependent FMN reductase
D1Y71_RS16640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D1Y71_RS16645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D1Y71_RS16650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D1Y71_RS16660	COG0308	aminopeptidase N
D1Y71_RS16670	COG1473	amidohydrolase
D1Y71_RS16680	COG0814	amino acid
D1Y71_RS16690	COG1522	sequence-specific DNA binding
D1Y71_RS16700	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D1Y71_RS16705	COG1448	Aminotransferase
D1Y71_RS16710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D1Y71_RS16715	COG3108	Peptidase M15
D1Y71_RS16720	COG2989	Protein conserved in bacteria
D1Y71_RS16730	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
D1Y71_RS16740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D1Y71_RS16745	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D1Y71_RS16750	COG3173	Aminoglycoside phosphotransferase
D1Y71_RS16765	COG3214	Protein conserved in bacteria
D1Y71_RS16780	COG0658	competence protein
D1Y71_RS16780	COG2333	competence protein COMEC
D1Y71_RS16790	COG0539	negative regulation of cytoplasmic translation
D1Y71_RS16810	COG2323	membrane
D1Y71_RS16815	COG1944	ATP diphosphatase activity
D1Y71_RS16820	COG2116	formate transmembrane transporter activity
D1Y71_RS16825	COG1882	Formate acetyltransferase
D1Y71_RS16830	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D1Y71_RS16835	COG0477	Major facilitator Superfamily
D1Y71_RS16845	COG3302	dmso reductase anchor subunit
D1Y71_RS16850	COG0437	4 iron, 4 sulfur cluster binding
D1Y71_RS16855	COG0243	molybdopterin cofactor binding
D1Y71_RS16865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D1Y71_RS16875	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D1Y71_RS16875	COG1674	ftsk spoiiie
D1Y71_RS16885	COG0492	ferredoxin-NADP+ reductase activity
D1Y71_RS16890	COG4988	ABC transporter
D1Y71_RS16895	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D1Y71_RS16910	COG0542	response to heat
D1Y71_RS16920	COG1278	Cold shock
D1Y71_RS16930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D1Y71_RS16935	COG3593	DNA synthesis involved in DNA repair
D1Y71_RS16945	COG2431	L-lysine efflux transmembrane transporter activity
D1Y71_RS16955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D1Y71_RS16965	COG0028	Belongs to the TPP enzyme family
D1Y71_RS16970	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
D1Y71_RS16975	COG0702	epimerase
D1Y71_RS16980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D1Y71_RS16985	COG3023	N-Acetylmuramoyl-L-alanine amidase
D1Y71_RS16990	COG2203	Gaf domain
D1Y71_RS16990	COG3706	GGDEF domain
D1Y71_RS16990	COG4251	negative regulation of phosphorylation
D1Y71_RS16990	COG5001	Diguanylate cyclase
D1Y71_RS17005	COG1126	abc transporter atp-binding protein
D1Y71_RS17010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1Y71_RS17015	COG4215	(ABC) transporter
D1Y71_RS17020	COG4160	amino acid transport
D1Y71_RS17025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1Y71_RS17030	COG5002	protein histidine kinase activity
D1Y71_RS17035	COG0745	RESPONSE REGULATOR receiver
D1Y71_RS17050	COG1177	transmembrane transport
D1Y71_RS17055	COG1176	ABC-type spermidine putrescine transport system, permease component I
D1Y71_RS17060	COG3842	ATPase activity
D1Y71_RS17065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D1Y71_RS17080	COG0778	Nitroreductase
D1Y71_RS17240	COG4695	Portal protein
D1Y71_RS17280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D1Y71_RS17320	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D1Y71_RS17325	COG3226	Transcriptional regulator
D1Y71_RS17330	COG0738	Major facilitator superfamily
D1Y71_RS17335	COG0561	phosphatase activity
D1Y71_RS17340	COG2814	Major facilitator Superfamily
D1Y71_RS17350	COG0671	phosphoesterase, PA-phosphatase related
D1Y71_RS17355	COG1349	DNA-binding transcription factor activity
D1Y71_RS17360	COG1686	Belongs to the peptidase S11 family
D1Y71_RS17365	COG0625	glutathione transferase activity
D1Y71_RS17370	COG2133	pyrroloquinoline quinone binding
D1Y71_RS17380	COG2223	nitrite transmembrane transporter activity
D1Y71_RS17405	COG0747	negative chemotaxis
D1Y71_RS17420	COG0303	'Molybdopterin
D1Y71_RS17425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D1Y71_RS17430	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D1Y71_RS17435	COG1882	Formate acetyltransferase
D1Y71_RS17440	COG0561	phosphatase activity
D1Y71_RS17450	COG1609	Transcriptional regulator
D1Y71_RS17455	COG2271	Major facilitator Superfamily
D1Y71_RS17470	COG0488	(ABC) transporter
D1Y71_RS17475	COG2365	Tyrosine phosphatase family
D1Y71_RS17480	COG1376	ErfK ybiS ycfS ynhG family protein
D1Y71_RS17485	COG2188	Transcriptional regulator
D1Y71_RS17490	COG2723	6-phospho-beta-galactosidase activity
D1Y71_RS17495	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D1Y71_RS17510	COG2194	sulfuric ester hydrolase activity
D1Y71_RS17515	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D1Y71_RS17530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1Y71_RS17535	COG0765	amino acid transport
D1Y71_RS17540	COG1126	abc transporter atp-binding protein
D1Y71_RS17545	COG0668	transmembrane transport
D1Y71_RS17555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D1Y71_RS17565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D1Y71_RS17575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D1Y71_RS17580	COG1199	ATP-dependent helicase activity
D1Y71_RS17585	COG0513	Belongs to the DEAD box helicase family
D1Y71_RS17590	COG3958	Transketolase
D1Y71_RS17595	COG3959	Transketolase, thiamine diphosphate binding domain
D1Y71_RS17600	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS17605	COG2271	Major facilitator Superfamily
D1Y71_RS17610	COG0583	DNA-binding transcription factor activity
D1Y71_RS17615	COG1309	transcriptional regulator
D1Y71_RS17620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D1Y71_RS17625	COG1131	(ABC) transporter
D1Y71_RS17630	COG0842	Transport permease protein
D1Y71_RS17635	COG0842	Transport permease protein
D1Y71_RS17645	COG3568	Endonuclease Exonuclease Phosphatase
D1Y71_RS17650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D1Y71_RS17655	COG0392	lysyltransferase activity
D1Y71_RS17670	COG0670	Belongs to the BI1 family
D1Y71_RS17675	COG0314	molybdopterin synthase activity
D1Y71_RS17680	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D1Y71_RS17690	COG0521	Mo-molybdopterin cofactor biosynthetic process
D1Y71_RS17715	COG0745	RESPONSE REGULATOR receiver
D1Y71_RS17720	COG0642	Histidine kinase
D1Y71_RS17755	COG2226	methyltransferase
D1Y71_RS17770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D1Y71_RS17775	COG1881	PFAM PEBP family protein
D1Y71_RS17815	COG4677	pectinesterase activity
D1Y71_RS17825	COG0589	response to stress
D1Y71_RS17830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D1Y71_RS17860	COG0789	Transcriptional regulator
D1Y71_RS17865	COG2200	EAL domain
D1Y71_RS17890	COG0561	phosphatase activity
D1Y71_RS17900	COG4149	molybdate abc transporter
D1Y71_RS17905	COG0725	ABC transporter, periplasmic molybdate-binding protein
D1Y71_RS17915	COG2005	Transcriptional regulator
D1Y71_RS17915	COG3585	molybdate ion transport
D1Y71_RS17920	COG1119	ATPase activity
D1Y71_RS17930	COG1085	galactose-1-phosphate uridylyltransferase
D1Y71_RS17940	COG2017	converts alpha-aldose to the beta-anomer
D1Y71_RS17950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D1Y71_RS17965	COG3201	nicotinamide mononucleotide transporter
D1Y71_RS17970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D1Y71_RS18015	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
D1Y71_RS18020	COG2885	chlorophyll binding
D1Y71_RS18030	COG3064	Membrane
D1Y71_RS18035	COG0848	biopolymer transport protein
D1Y71_RS18040	COG0811	peptide transport
D1Y71_RS18045	COG0824	Thioesterase
D1Y71_RS18050	COG3790	cyd operon protein YbgE
D1Y71_RS18055	COG4890	Cyd operon protein YbgT
D1Y71_RS18060	COG1294	oxidase, subunit
D1Y71_RS18065	COG1271	oxidase subunit
D1Y71_RS18075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D1Y71_RS18090	COG0508	dehydrogenase complex catalyzes the overall conversion of
D1Y71_RS18095	COG0567	Dehydrogenase, E1 component
D1Y71_RS18100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D1Y71_RS18105	COG1053	succinate dehydrogenase
D1Y71_RS18110	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D1Y71_RS18115	COG2009	succinate dehydrogenase
D1Y71_RS18150	COG1984	allophanate hydrolase subunit 2
D1Y71_RS18155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D1Y71_RS18170	COG0415	Belongs to the DNA photolyase family
D1Y71_RS18200	COG2205	protein histidine kinase activity
D1Y71_RS18205	COG0745	RESPONSE REGULATOR receiver
D1Y71_RS18215	COG0033	Phosphoglucomutase
D1Y71_RS18225	COG0596	Alpha beta hydrolase
D1Y71_RS18240	COG0735	belongs to the Fur family
D1Y71_RS18280	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D1Y71_RS18285	COG1846	Transcriptional regulator
D1Y71_RS18285	COG1940	carbohydrate kinase activity
D1Y71_RS18290	COG0647	UMP catabolic process
D1Y71_RS18295	COG0367	asparagine synthase
D1Y71_RS18340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D1Y71_RS18350	COG1702	phosphate starvation-inducible protein PhoH
D1Y71_RS18375	COG0765	amino acid transport
D1Y71_RS18380	COG0765	amino acid transport
D1Y71_RS18385	COG1126	abc transporter atp-binding protein
D1Y71_RS18400	COG2888	peptidyl-tyrosine sulfation
D1Y71_RS18415	COG1466	dna polymerase III delta subunit
D1Y71_RS18430	COG0799	negative regulation of ribosome biogenesis
D1Y71_RS18440	COG0768	penicillin binding
D1Y71_RS18445	COG0772	Belongs to the SEDS family
D1Y71_RS18450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D1Y71_RS18455	COG1686	Belongs to the peptidase S11 family
D1Y71_RS18470	COG0583	DNA-binding transcription factor activity
D1Y71_RS18480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D1Y71_RS18485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D1Y71_RS18510	COG3069	C4-dicarboxylate transmembrane transporter activity
D1Y71_RS18515	COG3719	Belongs to the RNase T2 family
D1Y71_RS18520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D1Y71_RS18540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D1Y71_RS18545	COG0583	DNA-binding transcription factor activity
D1Y71_RS18550	COG3969	phosphoadenosine phosphosulfate
D1Y71_RS18555	COG1475	DNA binding
D1Y71_RS18560	COG0436	Aminotransferase
D1Y71_RS18585	COG1129	ABC transporter
D1Y71_RS18590	COG1172	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS18595	COG1172	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS18605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D1Y71_RS18620	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D1Y71_RS18630	COG0402	S-adenosylhomocysteine deaminase activity
D1Y71_RS18640	COG0483	inositol monophosphate 1-phosphatase activity
D1Y71_RS18645	COG2271	Major facilitator Superfamily
D1Y71_RS18680	COG1172	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS18685	COG1129	ABC transporter
D1Y71_RS18690	COG0371	Dehydrogenase
D1Y71_RS18710	COG2879	small protein
D1Y71_RS18715	COG1966	Carbon starvation protein
D1Y71_RS18725	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS18730	COG3433	isochorismatase activity
D1Y71_RS18730	COG1535	isochorismatase
D1Y71_RS18735	COG1021	2,3-dihydroxybenzoate-AMP ligase
D1Y71_RS18740	COG1169	isochorismate synthase
D1Y71_RS18745	COG4592	Periplasmic binding protein
D1Y71_RS18750	COG0477	Major facilitator Superfamily
D1Y71_RS18755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1Y71_RS18760	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1Y71_RS18765	COG1120	ATPase activity
D1Y71_RS18770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D1Y71_RS18770	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D1Y71_RS18775	COG3251	PFAM MbtH domain protein
D1Y71_RS18780	COG2382	esterase
D1Y71_RS18790	COG4771	TonB-dependent receptor
D1Y71_RS18795	COG2977	Belongs to the P-Pant transferase superfamily
D1Y71_RS18800	COG3958	Transketolase
D1Y71_RS18805	COG3959	Transketolase, thiamine diphosphate binding domain
D1Y71_RS18815	COG2390	Transcriptional regulator
D1Y71_RS18820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D1Y71_RS18825	COG1879	ABC-type sugar transport system periplasmic component
D1Y71_RS18835	COG1129	ABC transporter
D1Y71_RS18840	COG1172	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS18845	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS18850	COG1028	Short-chain dehydrogenase reductase Sdr
D1Y71_RS18860	COG0583	DNA-binding transcription factor activity
D1Y71_RS18865	COG0668	transmembrane transport
D1Y71_RS18875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D1Y71_RS18900	COG0747	negative chemotaxis
D1Y71_RS18905	COG0601	transmembrane transport
D1Y71_RS18910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D1Y71_RS18915	COG0444	Belongs to the ABC transporter superfamily
D1Y71_RS18920	COG4608	Belongs to the ABC transporter superfamily
D1Y71_RS18925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D1Y71_RS18930	COG4221	oxidoreductase activity
D1Y71_RS18940	COG4215	(ABC) transporter
D1Y71_RS18950	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
D1Y71_RS18965	COG0697	spore germination
D1Y71_RS18975	COG3698	Phosphodiester glycosidase
D1Y71_RS19020	COG2315	Protein conserved in bacteria
D1Y71_RS19025	COG0778	Nitroreductase
D1Y71_RS19035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1Y71_RS19045	COG3716	PTS system mannose fructose sorbose family IID component
D1Y71_RS19050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D1Y71_RS19055	COG2222	sugar isomerase
D1Y71_RS19070	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D1Y71_RS19070	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D1Y71_RS19090	COG0477	Major facilitator Superfamily
D1Y71_RS19095	COG0668	transmembrane transport
D1Y71_RS19100	COG1609	Transcriptional regulator
D1Y71_RS19110	COG0673	inositol 2-dehydrogenase activity
D1Y71_RS19120	COG2211	Major facilitator Superfamily
D1Y71_RS19125	COG1113	amino acid transport
D1Y71_RS19140	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS19145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D1Y71_RS19155	COG0531	amino acid
D1Y71_RS19205	COG0667	Aldo Keto reductase
D1Y71_RS19210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1Y71_RS19215	COG1473	amidohydrolase
D1Y71_RS19240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1Y71_RS19245	COG1120	ATPase activity
D1Y71_RS19250	COG1566	PFAM secretion protein HlyD family protein
D1Y71_RS19295	COG4211	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS19300	COG1129	ABC transporter
D1Y71_RS19315	COG0673	inositol 2-dehydrogenase activity
D1Y71_RS19345	COG3104	oligopeptide transport
D1Y71_RS19350	COG1982	Orn Lys Arg decarboxylase major
D1Y71_RS19355	COG0531	amino acid
D1Y71_RS19360	COG3710	Transcriptional regulator
D1Y71_RS19375	COG1560	Kdo2-lipid A biosynthetic process
D1Y71_RS19390	COG3188	usher protein
D1Y71_RS19395	COG3121	Chaperone
D1Y71_RS19400	COG3539	Fimbrial protein
D1Y71_RS19430	COG2501	S4 domain
D1Y71_RS19440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D1Y71_RS19455	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D1Y71_RS19460	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D1Y71_RS19475	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
D1Y71_RS19480	COG4181	ATPase activity
D1Y71_RS19485	COG2755	lipolytic protein G-D-S-L family
D1Y71_RS19490	COG0300	oxidoreductase activity
D1Y71_RS19495	COG3118	belongs to the thioredoxin family
D1Y71_RS19505	COG0390	transport system, permease component
D1Y71_RS19510	COG4619	ABC transporter
D1Y71_RS19515	COG0330	HflC and HflK could
D1Y71_RS19520	COG1585	Membrane protein implicated in regulation of membrane protease activity
D1Y71_RS19535	COG3735	TraB family
D1Y71_RS19540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D1Y71_RS19550	COG2223	nitrite transmembrane transporter activity
D1Y71_RS19555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D1Y71_RS19555	COG4651	solute:proton antiporter activity
D1Y71_RS19560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D1Y71_RS19600	COG2832	Protein of unknown function (DUF454)
D1Y71_RS19605	COG3923	Primosomal replication protein n
D1Y71_RS19615	COG5464	transposase or invertase
D1Y71_RS19620	COG1196	nuclear chromosome segregation
D1Y71_RS19620	COG3264	Mechanosensitive ion channel
D1Y71_RS19625	COG1309	transcriptional regulator
D1Y71_RS19630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D1Y71_RS19635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D1Y71_RS19650	COG0110	maltose O-acetyltransferase activity
D1Y71_RS19695	COG1874	Beta-galactosidase
D1Y71_RS19700	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D1Y71_RS19705	COG3833	ABC-type maltose transport systems, permease component
D1Y71_RS19710	COG1175	transmembrane transport
D1Y71_RS19715	COG2182	Extracellular solute-binding protein
D1Y71_RS19725	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D1Y71_RS19740	COG2364	Membrane
D1Y71_RS19770	COG3695	enzyme binding
D1Y71_RS19775	COG3126	Type III secretion system lipoprotein chaperone (YscW)
D1Y71_RS19780	COG1946	Acyl-CoA thioesterase
D1Y71_RS19785	COG0004	ammonium transporteR
D1Y71_RS19790	COG0347	Belongs to the P(II) protein family
D1Y71_RS19795	COG1132	(ABC) transporter
D1Y71_RS19800	COG1132	(ABC) transporter
D1Y71_RS19805	COG1522	sequence-specific DNA binding
D1Y71_RS19820	COG4533	DNA binding
D1Y71_RS19830	COG0824	Thioesterase
D1Y71_RS19835	COG1555	photosystem II stabilization
D1Y71_RS19840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D1Y71_RS19845	COG0776	regulation of translation
D1Y71_RS19850	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D1Y71_RS19880	COG0271	Belongs to the BolA IbaG family
D1Y71_RS19885	COG3056	Lipoprotein
D1Y71_RS19890	COG2223	nitrite transmembrane transporter activity
D1Y71_RS19895	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D1Y71_RS19900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D1Y71_RS19905	COG1845	cytochrome c oxidase, subunit III
D1Y71_RS19910	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D1Y71_RS19925	COG1414	Transcriptional regulator
D1Y71_RS19930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D1Y71_RS19935	COG1053	succinate dehydrogenase
D1Y71_RS19945	COG1053	succinate dehydrogenase
D1Y71_RS19960	COG0673	inositol 2-dehydrogenase activity
D1Y71_RS19965	COG2814	Major facilitator Superfamily
D1Y71_RS19975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D1Y71_RS19980	COG0693	protein deglycase activity
D1Y71_RS20000	COG0142	geranyltranstransferase activity
D1Y71_RS20010	COG0667	Aldo Keto reductase
D1Y71_RS20015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D1Y71_RS20035	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D1Y71_RS20035	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D1Y71_RS20045	COG4238	major outer membrane lipoprotein
D1Y71_RS20065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D1Y71_RS20070	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D1Y71_RS20075	COG1862	Preprotein translocase
D1Y71_RS20095	COG0450	alkyl hydroperoxide reductase
D1Y71_RS20100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1Y71_RS20115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D1Y71_RS20125	COG1228	amidohydrolase
D1Y71_RS20135	COG1335	isochorismatase
D1Y71_RS20140	COG0583	DNA-binding transcription factor activity
D1Y71_RS20145	COG0366	Alpha amylase catalytic
D1Y71_RS20170	COG0420	3'-5' exonuclease activity
D1Y71_RS20175	COG0419	ATPase involved in DNA repair
D1Y71_RS20180	COG1940	carbohydrate kinase activity
D1Y71_RS20195	COG4126	flavin adenine dinucleotide binding
D1Y71_RS20205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D1Y71_RS20210	COG3416	Protein conserved in bacteria
D1Y71_RS20220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D1Y71_RS20230	COG1785	Belongs to the alkaline phosphatase family
D1Y71_RS20270	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
D1Y71_RS20275	COG1335	isochorismatase
D1Y71_RS20280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D1Y71_RS20285	COG0113	porphobilinogen synthase activity
D1Y71_RS20295	COG2175	clavaminate synthase activity
D1Y71_RS20300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D1Y71_RS20305	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D1Y71_RS20310	COG4521	taurine ABC transporter
D1Y71_RS20315	COG2040	homocysteine
D1Y71_RS20320	COG0833	amino acid
D1Y71_RS20330	COG4303	Ethanolamine ammonia lyase large subunit
D1Y71_RS20335	COG4302	ethanolamine ammonia-lyase activity
D1Y71_RS20375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1Y71_RS20380	COG1126	abc transporter atp-binding protein
D1Y71_RS20385	COG4597	amino acid ABC transporter
D1Y71_RS20390	COG0765	amino acid transport
D1Y71_RS20405	COG3188	usher protein
D1Y71_RS20430	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
D1Y71_RS20440	COG3639	organic phosphonate transmembrane transporter activity
D1Y71_RS20480	COG0791	NLP P60 protein
D1Y71_RS20525	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D1Y71_RS20585	COG0582	viral genome integration into host DNA
D1Y71_RS20665	COG1126	abc transporter atp-binding protein
D1Y71_RS20670	COG0765	amino acid transport
D1Y71_RS20680	COG4221	oxidoreductase activity
D1Y71_RS20695	COG0436	Aminotransferase
D1Y71_RS20700	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D1Y71_RS20705	COG1984	allophanate hydrolase subunit 2
D1Y71_RS20720	COG0697	spore germination
D1Y71_RS20725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D1Y71_RS20730	COG0439	Biotin carboxylase
D1Y71_RS20735	COG0511	ligase activity, forming carbon-carbon bonds
D1Y71_RS20745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D1Y71_RS20750	COG0022	dehydrogenase e1 component
D1Y71_RS20755	COG0508	dehydrogenase complex catalyzes the overall conversion of
D1Y71_RS20760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D1Y71_RS20770	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D1Y71_RS20790	COG0579	oxidoreductase
D1Y71_RS20795	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS20800	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D1Y71_RS20805	COG1113	amino acid transport
D1Y71_RS20810	COG1802	Transcriptional regulator
D1Y71_RS20830	COG2195	Cleaves the N-terminal amino acid of tripeptides
D1Y71_RS20835	COG0454	-acetyltransferase
D1Y71_RS20850	COG2991	Protein conserved in bacteria
D1Y71_RS20865	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D1Y71_RS20870	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D1Y71_RS20890	COG3034	peptidoglycan biosynthetic process
D1Y71_RS20895	COG0121	glutamine amidotransferase
D1Y71_RS20905	COG1960	acyl-CoA dehydrogenase activity
D1Y71_RS20910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D1Y71_RS20920	COG0583	DNA-binding transcription factor activity
D1Y71_RS20930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D1Y71_RS20940	COG2226	methyltransferase
D1Y71_RS20950	COG0741	lytic transglycosylase activity
D1Y71_RS20950	COG1388	LysM domain
D1Y71_RS20955	COG2226	methyltransferase
D1Y71_RS20965	COG2814	Major facilitator Superfamily
D1Y71_RS20970	COG0583	DNA-binding transcription factor activity
D1Y71_RS20975	COG0656	L-ascorbic acid biosynthetic process
D1Y71_RS21010	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D1Y71_RS21020	COG2011	ABC-type metal ion transport system permease component
D1Y71_RS21025	COG1464	Belongs to the NlpA lipoprotein family
D1Y71_RS21035	COG1720	tRNA m6t6A37 methyltransferase activity
D1Y71_RS21045	COG0791	NLP P60 protein
D1Y71_RS21050	COG3015	lipoprotein NlpE involved in copper resistance
D1Y71_RS21055	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
D1Y71_RS21070	COG4568	rho-dependent transcription termination
D1Y71_RS21080	COG0346	lactoylglutathione lyase activity
D1Y71_RS21085	COG1982	Orn Lys Arg decarboxylase major
D1Y71_RS21125	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
D1Y71_RS21135	COG0750	zinc metalloprotease
D1Y71_RS21140	COG0575	Belongs to the CDS family
D1Y71_RS21155	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D1Y71_RS21180	COG0024	Methionine aminopeptidase
D1Y71_RS21185	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
D1Y71_RS21200	COG3835	regulator
D1Y71_RS21205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D1Y71_RS21225	COG2860	membrane
D1Y71_RS21245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D1Y71_RS21250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D1Y71_RS21255	COG1120	ATPase activity
D1Y71_RS21260	COG4774	siderophore transport
D1Y71_RS21265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D1Y71_RS21350	COG1643	Atp-dependent helicase
D1Y71_RS21355	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D1Y71_RS21375	COG0617	tRNA 3'-terminal CCA addition
D1Y71_RS21380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D1Y71_RS21400	COG0726	polysaccharide deacetylase
D1Y71_RS21405	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1Y71_RS21410	COG0842	Transport permease protein
D1Y71_RS21415	COG1131	(ABC) transporter
D1Y71_RS21420	COG0288	reversible hydration of carbon dioxide
D1Y71_RS21430	COG4993	Dehydrogenase
D1Y71_RS21435	COG2132	Multicopper oxidase
D1Y71_RS21480	COG3064	Membrane
D1Y71_RS21495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D1Y71_RS21500	COG0508	dehydrogenase complex catalyzes the overall conversion of
D1Y71_RS21505	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D1Y71_RS21510	COG2186	Transcriptional regulator
D1Y71_RS21515	COG1113	amino acid transport
D1Y71_RS21520	COG2211	Major facilitator Superfamily
D1Y71_RS21525	COG3940	Belongs to the glycosyl hydrolase 43 family
D1Y71_RS21530	COG3725	Membrane protein required for beta-lactamase induction
D1Y71_RS21535	COG3023	N-Acetylmuramoyl-L-alanine amidase
D1Y71_RS21545	COG4969	Belongs to the N-Me-Phe pilin family
D1Y71_RS21550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D1Y71_RS21555	COG1459	type II secretion system
D1Y71_RS21580	COG0494	nUDIX hydrolase
D1Y71_RS21600	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D1Y71_RS21605	COG0849	cell division
D1Y71_RS21630	COG0772	Belongs to the SEDS family
D1Y71_RS21645	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D1Y71_RS21650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D1Y71_RS21655	COG0768	penicillin binding
D1Y71_RS21675	COG1609	Transcriptional regulator
D1Y71_RS21685	COG0028	Belongs to the TPP enzyme family
D1Y71_RS21735	COG0738	Major facilitator superfamily
D1Y71_RS21745	COG0583	DNA-binding transcription factor activity
D1Y71_RS21750	COG2271	Major facilitator Superfamily
D1Y71_RS21755	COG2814	Major facilitator Superfamily
D1Y71_RS21775	COG1178	ABC-type Fe3 transport system permease component
D1Y71_RS21785	COG0586	Pfam SNARE associated Golgi protein
D1Y71_RS21805	COG0235	Class ii aldolase
D1Y71_RS21810	COG0417	DNA replication proofreading
D1Y71_RS21820	COG0564	pseudouridine synthase activity
D1Y71_RS21835	COG3493	citrate carrier protein
D1Y71_RS21850	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D1Y71_RS21855	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
D1Y71_RS21865	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D1Y71_RS21910	COG0505	Belongs to the CarA family
D1Y71_RS21975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D1Y71_RS22000	COG1047	Peptidyl-prolyl cis-trans
D1Y71_RS22015	COG0196	riboflavin kinase activity
D1Y71_RS22030	COG0583	DNA-binding transcription factor activity
D1Y71_RS22055	COG4735	regulation of single-species biofilm formation
D1Y71_RS22060	COG1584	GPR1 FUN34 yaaH family protein
D1Y71_RS22065	COG0477	Major facilitator Superfamily
D1Y71_RS22070	COG0521	Mo-molybdopterin cofactor biosynthetic process
D1Y71_RS22075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D1Y71_RS22080	COG1115	amino acid carrier protein
D1Y71_RS22095	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D1Y71_RS22105	COG0460	homoserine dehydrogenase
D1Y71_RS22105	COG0527	aspartate kinase activity
D1Y71_RS22115	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
D1Y71_RS22125	COG0745	RESPONSE REGULATOR receiver
D1Y71_RS22130	COG4452	Inner membrane protein CreD
D1Y71_RS22135	COG2205	protein histidine kinase activity
D1Y71_RS22140	COG0745	RESPONSE REGULATOR receiver
D1Y71_RS22145	COG3045	CreA protein
D1Y71_RS22150	COG2207	Transcriptional regulator
D1Y71_RS22150	COG3708	Transcriptional regulator
D1Y71_RS22170	COG0741	lytic transglycosylase activity
D1Y71_RS22175	COG0488	(ABC) transporter
D1Y71_RS22185	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D1Y71_RS22190	COG0560	Phosphoserine phosphatase
D1Y71_RS22195	COG3726	membrane protein affecting hemolysin expression
D1Y71_RS22225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D1Y71_RS22230	COG0084	hydrolase, TatD family'
D1Y71_RS22235	COG4667	esterase of the alpha-beta hydrolase superfamily
D1Y71_RS22245	COG2823	Periplasmic or secreted lipoprotein
D1Y71_RS22255	COG1011	Hydrolase
D1Y71_RS22260	COG0456	acetyltransferase
D1Y71_RS22265	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
D1Y71_RS22295	COG3706	GGDEF domain
D1Y71_RS22300	COG4114	ferric iron reductase
D1Y71_RS22305	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1Y71_RS22305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1Y71_RS22310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D1Y71_RS22315	COG2197	response regulator
D1Y71_RS22320	COG2197	response regulator
D1Y71_RS22340	COG2966	Psort location CytoplasmicMembrane, score
D1Y71_RS22355	COG1484	DNA-dependent DNA replication
D1Y71_RS22380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D1Y71_RS22385	COG3716	PTS system mannose fructose sorbose family IID component
D1Y71_RS22390	COG3715	PTS system
D1Y71_RS22405	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D1Y71_RS22405	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D1Y71_RS22410	COG1214	PFAM Peptidase M22, glycoprotease
D1Y71_RS22410	COG0456	acetyltransferase
D1Y71_RS22420	COG1737	Transcriptional regulator
D1Y71_RS22425	COG0800	Aldolase
D1Y71_RS22430	COG3734	2-keto-3-deoxy-galactonokinase
D1Y71_RS22445	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
D1Y71_RS22475	COG1846	Transcriptional regulator
D1Y71_RS22480	COG0179	Fumarylacetoacetate (FAA) hydrolase
D1Y71_RS22490	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS22495	COG3384	dioxygenase
D1Y71_RS22505	COG3971	2-oxopent-4-enoate hydratase activity
D1Y71_RS22525	COG2368	4-hydroxyphenylacetate
D1Y71_RS22530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D1Y71_RS22545	COG1966	Carbon starvation protein
D1Y71_RS22550	COG2879	small protein
D1Y71_RS22555	COG0523	cobalamin synthesis protein
D1Y71_RS22565	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS22570	COG5464	transposase or invertase
D1Y71_RS22575	COG1917	Cupin 2, conserved barrel domain protein
D1Y71_RS22575	COG2207	Transcriptional regulator
D1Y71_RS22585	COG2733	membrane
D1Y71_RS22600	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
D1Y71_RS22605	COG1924	4 iron, 4 sulfur cluster binding
D1Y71_RS22620	COG1566	PFAM secretion protein HlyD family protein
D1Y71_RS22630	COG5457	Domain of unknown function (DUF1127)
D1Y71_RS22635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D1Y71_RS22645	COG0583	DNA-binding transcription factor activity
D1Y71_RS22650	COG2249	NAD(P)H dehydrogenase (quinone) activity
D1Y71_RS22685	COG1454	alcohol dehydrogenase
D1Y71_RS22685	COG1012	belongs to the aldehyde dehydrogenase family
D1Y71_RS22700	COG1882	Formate acetyltransferase
D1Y71_RS22705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D1Y71_RS22715	COG4869	propanediol catabolic process
D1Y71_RS22740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D1Y71_RS22745	COG0842	Transport permease protein
D1Y71_RS22745	COG1129	ABC transporter
D1Y71_RS22750	COG0842	Transport permease protein
D1Y71_RS22785	COG2850	peptidyl-arginine hydroxylation
D1Y71_RS22800	COG5002	protein histidine kinase activity
D1Y71_RS22805	COG0745	RESPONSE REGULATOR receiver
D1Y71_RS22815	COG1538	Outer membrane efflux protein
D1Y71_RS22820	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D1Y71_RS22825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D1Y71_RS22830	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D1Y71_RS22840	COG3040	lipid binding
D1Y71_RS22845	COG0789	Transcriptional regulator
D1Y71_RS22855	COG0300	oxidoreductase activity
D1Y71_RS22870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D1Y71_RS22890	COG3272	Protein of unknown function (DUF1722)
D1Y71_RS22895	COG4580	involved in the transport of maltose and maltodextrins
D1Y71_RS22900	COG2115	Belongs to the xylose isomerase family
D1Y71_RS22915	COG0582	viral genome integration into host DNA
D1Y71_RS22930	COG0288	reversible hydration of carbon dioxide
D1Y71_RS22935	COG0659	secondary active sulfate transmembrane transporter activity
D1Y71_RS22940	COG1064	alcohol dehydrogenase
D1Y71_RS22945	COG1175	transmembrane transport
D1Y71_RS22950	COG0395	ABC-type sugar transport system, permease component
D1Y71_RS22955	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D1Y71_RS22960	COG3842	ATPase activity
D1Y71_RS22975	COG1082	Xylose isomerase domain protein TIM barrel
D1Y71_RS22985	COG3962	Belongs to the TPP enzyme family
D1Y71_RS22990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D1Y71_RS22995	COG0837	glucose binding
D1Y71_RS22995	COG1737	Transcriptional regulator
D1Y71_RS23005	COG3718	enzyme involved in inositol metabolism
D1Y71_RS23020	COG0433	COG0433 Predicted ATPase
D1Y71_RS23025	COG0795	lipopolysaccharide-transporting ATPase activity
D1Y71_RS23030	COG0795	lipopolysaccharide-transporting ATPase activity
D1Y71_RS23045	COG2927	DNA polymerase III (CHI subunit)
D1Y71_RS23050	COG0525	valine-tRNA ligase activity
D1Y71_RS23075	COG2188	Transcriptional regulator
D1Y71_RS23080	COG1288	antiporter activity
D1Y71_RS23085	COG1228	amidohydrolase
D1Y71_RS23090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D1Y71_RS23095	COG2222	sugar isomerase
D1Y71_RS23100	COG2731	YhcH YjgK YiaL family protein
D1Y71_RS23145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D1Y71_RS23145	COG1263	PTS System
D1Y71_RS23150	COG0366	Alpha amylase catalytic
D1Y71_RS23155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D1Y71_RS23160	COG1486	melibiose metabolic process
D1Y71_RS23180	COG0602	queuosine metabolic process
D1Y71_RS23185	COG2026	Addiction module toxin, RelE StbE family
D1Y71_RS23190	COG3077	Addiction module antitoxin, RelB DinJ family
D1Y71_RS23195	COG3711	transcriptional antiterminator
D1Y71_RS23195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D1Y71_RS23200	COG2706	6-phosphogluconolactonase activity
D1Y71_RS23215	COG3964	amidohydrolase
D1Y71_RS23250	COG0312	modulator of DNA gyrase
D1Y71_RS23275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D1Y71_RS23285	COG1172	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS23290	COG1172	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS23295	COG1129	ABC transporter
D1Y71_RS23300	COG1879	ABC-type sugar transport system periplasmic component
D1Y71_RS23315	COG2105	PFAM AIG2 family protein
D1Y71_RS23320	COG2911	Protein conserved in bacteria
D1Y71_RS23325	COG0729	surface antigen
D1Y71_RS23335	COG1253	flavin adenine dinucleotide binding
D1Y71_RS23350	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
D1Y71_RS23365	COG1733	regulation of RNA biosynthetic process
D1Y71_RS23370	COG0702	epimerase
D1Y71_RS23380	COG0697	spore germination
D1Y71_RS23390	COG1113	amino acid transport
D1Y71_RS23395	COG0545	Peptidyl-prolyl cis-trans isomerase
D1Y71_RS23400	COG3061	Opacity-associated protein A
D1Y71_RS23410	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D1Y71_RS23415	COG2965	DNA replication, synthesis of RNA primer
D1Y71_RS23475	COG1073	alpha beta
D1Y71_RS23480	COG3650	response to hydrogen peroxide
D1Y71_RS23490	COG1960	acyl-CoA dehydrogenase activity
D1Y71_RS23495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D1Y71_RS23500	COG0557	exoribonuclease II activity
D1Y71_RS23515	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
D1Y71_RS23525	COG0330	HflC and HflK could
D1Y71_RS23530	COG0330	HflC and HflK could
D1Y71_RS23535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D1Y71_RS23555	COG0860	N-Acetylmuramoyl-L-alanine amidase
D1Y71_RS23560	COG0802	atpase or kinase
D1Y71_RS23565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D1Y71_RS23565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D1Y71_RS23570	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D1Y71_RS23595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D1Y71_RS23615	COG1511	domain protein
D1Y71_RS23615	COG3264	Mechanosensitive ion channel
D1Y71_RS23630	COG1053	succinate dehydrogenase
D1Y71_RS23635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D1Y71_RS23655	COG2076	Multidrug Resistance protein
D1Y71_RS23660	COG5510	response to toxic substance
D1Y71_RS23675	COG1509	lysine 2,3-aminomutase activity
D1Y71_RS23750	COG0531	amino acid
D1Y71_RS23755	COG3030	protein affecting phage T7 exclusion by the F plasmid
D1Y71_RS23765	COG1027	Aspartate ammonia-lyase
D1Y71_RS23770	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D1Y71_RS23785	COG1309	transcriptional regulator
D1Y71_RS23820	COG0457	Tetratricopeptide repeat
D1Y71_RS23825	COG0726	polysaccharide deacetylase
D1Y71_RS23825	COG1649	PFAM Uncharacterised BCR, COG1649
D1Y71_RS23830	COG1215	transferase activity, transferring glycosyl groups
D1Y71_RS23850	COG0861	Integral membrane protein TerC family
D1Y71_RS23885	COG1486	melibiose metabolic process
D1Y71_RS23895	COG2169	Transcriptional regulator
D1Y71_RS23910	COG2824	Alkylphosphonate utilization operon protein PhnA
D1Y71_RS23915	COG2764	glyoxalase bleomycin resistance protein dioxygenase
D1Y71_RS23920	COG2188	Transcriptional regulator
D1Y71_RS23925	COG3624	Phosphonate C-P lyase system protein PhnG
D1Y71_RS23930	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
D1Y71_RS23935	COG3626	phosphonate metabolism
D1Y71_RS23940	COG3627	carbon phosphorus lyase activity
D1Y71_RS23945	COG4107	phosphonate C-P lyase system protein PhnK
D1Y71_RS23950	COG4778	phosphonate C-P lyase system protein PhnL
D1Y71_RS23955	COG3454	Phosphonate metabolism
D1Y71_RS23965	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D1Y71_RS23975	COG4191	Histidine kinase
D1Y71_RS23975	COG0784	Response regulator, receiver
D1Y71_RS23980	COG1129	ABC transporter
D1Y71_RS23985	COG1172	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS24025	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
D1Y71_RS24030	COG1301	dicarboxylic acid transport
D1Y71_RS24040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D1Y71_RS24050	COG3162	membrane
D1Y71_RS24080	COG1346	cytolysis
D1Y71_RS24085	COG1380	Effector of murein hydrolase LrgA
D1Y71_RS24090	COG0583	DNA-binding transcription factor activity
D1Y71_RS24095	COG0025	NhaP-type Na H and K H
D1Y71_RS24100	COG2252	PERMEase
D1Y71_RS24105	COG0625	glutathione transferase activity
D1Y71_RS24110	COG0789	Transcriptional regulator
D1Y71_RS24120	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D1Y71_RS24155	COG1234	tRNA 3'-trailer cleavage
D1Y71_RS24160	COG1609	Transcriptional regulator
D1Y71_RS24165	COG0483	inositol monophosphate 1-phosphatase activity
D1Y71_RS24180	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D1Y71_RS24200	COG4771	TonB-dependent receptor
D1Y71_RS24205	COG0741	lytic transglycosylase activity
D1Y71_RS24220	COG2315	Protein conserved in bacteria
D1Y71_RS24225	COG0432	Pfam Uncharacterised protein family UPF0047
D1Y71_RS24240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D1Y71_RS24245	COG0305	Participates in initiation and elongation during chromosome replication
D1Y71_RS24260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D1Y71_RS24270	COG0735	belongs to the Fur family
D1Y71_RS24275	COG3237	CsbD-like
D1Y71_RS24280	COG0534	Mate efflux family protein
D1Y71_RS24290	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D1Y71_RS24375	COG0251	oxidation-reduction process
D1Y71_RS24385	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D1Y71_RS24405	COG0527	aspartate kinase activity
D1Y71_RS24460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D1Y71_RS24490	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D1Y71_RS24500	COG0456	acetyltransferase
D1Y71_RS24535	COG0151	Belongs to the GarS family
D1Y71_RS24545	COG4191	Histidine kinase
D1Y71_RS24550	COG3678	ATP-independent chaperone mediated protein folding
D1Y71_RS24585	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
D1Y71_RS24600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D1Y71_RS24605	COG2104	thiamine diphosphate biosynthetic process
D1Y71_RS24620	COG3706	GGDEF domain
D1Y71_RS24630	COG1447	Phosphotransferase system cellobiose-specific component IIA
D1Y71_RS24635	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D1Y71_RS24670	COG0250	Participates in transcription elongation, termination and antitermination
D1Y71_RS24745	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
D1Y71_RS24755	COG1739	Uncharacterized protein family UPF0029
D1Y71_RS24800	COG0805	protein transport
D1Y71_RS24820	COG3165	ubiquinone biosynthetic process from chorismate
D1Y71_RS24850	COG0583	DNA-binding transcription factor activity
D1Y71_RS24855	COG0697	spore germination
D1Y71_RS24860	COG0561	phosphatase activity
D1Y71_RS24865	COG2267	carboxylic ester hydrolase activity
D1Y71_RS24870	COG1280	lysine exporter protein (LysE YggA)
D1Y71_RS24880	COG1280	lysine exporter protein (LysE YggA)
D1Y71_RS24915	COG0210	DNA helicase
D1Y71_RS24920	COG1011	Hydrolase
D1Y71_RS24950	COG3072	Adenylate cyclase
D1Y71_RS24965	COG2959	enzyme of heme biosynthesis
D1Y71_RS24970	COG3071	HemY protein
D1Y71_RS25015	COG2244	polysaccharide biosynthetic process
D1Y71_RS25020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D1Y71_RS25025	COG0456	acetyltransferase
D1Y71_RS25030	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D1Y71_RS25035	COG1088	dTDP-glucose 4,6-dehydratase activity
D1Y71_RS25040	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D1Y71_RS25045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D1Y71_RS25055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D1Y71_RS25060	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D1Y71_RS25070	COG3118	belongs to the thioredoxin family
D1Y71_RS25100	COG1811	Na channel or pump
D1Y71_RS25110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D1Y71_RS25115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D1Y71_RS25125	COG0583	DNA-binding transcription factor activity
D1Y71_RS25130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D1Y71_RS25145	COG3978	acetolactate synthase activity
D1Y71_RS25165	COG3085	chromosome segregation
D1Y71_RS25240	COG0583	DNA-binding transcription factor activity
D1Y71_RS25265	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D1Y71_RS25280	COG3443	Belongs to the bacterial solute-binding protein 9 family
D1Y71_RS25285	COG2207	Transcriptional regulator
D1Y71_RS25295	COG0371	Dehydrogenase
D1Y71_RS25300	COG0697	spore germination
D1Y71_RS25310	COG0583	DNA-binding transcription factor activity
D1Y71_RS25320	COG0737	Belongs to the 5'-nucleotidase family
D1Y71_RS25330	COG0527	aspartate kinase activity
D1Y71_RS25330	COG0460	homoserine dehydrogenase
D1Y71_RS25335	COG0626	cystathionine gamma-synthase activity
D1Y71_RS25350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D1Y71_RS25355	COG1609	Transcriptional regulator
D1Y71_RS25360	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D1Y71_RS25375	COG1575	Belongs to the MenA family. Type 1 subfamily
D1Y71_RS25395	COG3678	ATP-independent chaperone mediated protein folding
D1Y71_RS25400	COG0745	RESPONSE REGULATOR receiver
D1Y71_RS25405	COG2205	protein histidine kinase activity
D1Y71_RS25410	COG2258	MOSC domain
D1Y71_RS25415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D1Y71_RS25460	COG1129	ABC transporter
D1Y71_RS25465	COG1172	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS25470	COG1172	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS25475	COG1454	alcohol dehydrogenase
D1Y71_RS25485	COG2211	Major facilitator Superfamily
D1Y71_RS25545	COG0205	6-phosphofructokinase activity
D1Y71_RS25565	COG0437	4 iron, 4 sulfur cluster binding
D1Y71_RS25570	COG2864	formate dehydrogenase
D1Y71_RS25585	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D1Y71_RS25595	COG0456	acetyltransferase
D1Y71_RS25610	COG1011	Hydrolase
D1Y71_RS25625	COG3852	Histidine kinase
D1Y71_RS25640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D1Y71_RS25665	COG0204	Acyl-transferase
D1Y71_RS25675	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D1Y71_RS25680	COG3084	Protein conserved in bacteria
D1Y71_RS25690	COG1763	Mo-molybdopterin cofactor biosynthetic process
D1Y71_RS25720	COG2186	Transcriptional regulator
D1Y71_RS25725	COG0477	Major facilitator Superfamily
D1Y71_RS25730	COG1609	Transcriptional regulator
D1Y71_RS25735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D1Y71_RS25745	COG1172	Belongs to the binding-protein-dependent transport system permease family
D1Y71_RS25750	COG1129	ABC transporter
D1Y71_RS25780	COG1522	sequence-specific DNA binding
D1Y71_RS25785	COG0716	FMN binding
D1Y71_RS25800	COG3312	ion transport
D1Y71_RS25855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D1Y71_RS25860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D1Y71_RS25865	COG0573	inorganic phosphate transmembrane transporter activity
D1Y71_RS25870	COG0581	inorganic phosphate transmembrane transporter activity
D1Y71_RS25875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D1Y71_RS25880	COG0704	Plays a role in the regulation of phosphate uptake
D1Y71_RS25895	COG2382	esterase
D1Y71_RS25900	COG0363	glucosamine-6-phosphate deaminase activity
D1Y71_RS25905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D1Y71_RS25915	COG2252	PERMEase
D1Y71_RS25920	COG0431	NADPH-dependent FMN reductase
D1Y71_RS25925	COG2091	lysine biosynthetic process via aminoadipic acid
D1Y71_RS25955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D1Y71_RS26030	COG1192	Involved in chromosome partitioning
D1Y71_RS26115	COG0210	DNA helicase
D1Y71_RS26225	COG2826	transposase and inactivated derivatives, IS30 family
D1Y71_RS26270	COG4245	von Willebrand factor, type A
D1Y71_RS26275	COG4245	von Willebrand factor, type A
D1Y71_RS26305	COG1358	cellular component organization or biogenesis
D1Y71_RS26395	COG3550	peptidyl-serine autophosphorylation
D1Y71_RS26475	COG3173	Aminoglycoside phosphotransferase
D1Y71_RS26670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D1Y71_RS26795	COG4221	oxidoreductase activity
D1Y71_RS26835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D1Y71_RS26835	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D1Y71_RS26855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D1Y71_RS27020	COG3385	transposase activity
D1Y71_RS27190	COG2890	protein-(glutamine-N5) methyltransferase activity
D1Y71_RS27275	COG2826	transposase and inactivated derivatives, IS30 family
D1Y71_RS27350	COG3842	ATPase activity
D1Y71_RS27360	COG0483	inositol monophosphate 1-phosphatase activity
D1Y71_RS27385	COG0477	Major facilitator Superfamily
D1Y71_RS27390	COG0235	Class ii aldolase
D1Y71_RS27395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D1Y71_RS27405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D1Y71_RS27410	COG0477	Major facilitator Superfamily
D1Y71_RS27415	COG0251	oxidation-reduction process
D1Y71_RS27420	COG0583	DNA-binding transcription factor activity
D1Y71_RS27440	COG0071	Belongs to the small heat shock protein (HSP20) family
D1Y71_RS27445	COG0542	response to heat
D1Y71_RS27505	COG0501	Belongs to the peptidase M48B family
D1Y71_RS27510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D1Y71_RS27560	COG2234	aminopeptidase activity
D1Y71_RS27570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D1Y71_RS27600	COG2135	peptidase activity
D1Y71_RS27615	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
D1Y71_RS27655	COG4124	Belongs to the glycosyl hydrolase 26 family
D1Y71_RS27730	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D1Y71_RS27735	COG3012	SEC-C Motif Domain Protein
D1Y71_RS27735	COG3318	Belongs to the UPF0149 family
D1Y71_RS27885	COG5499	transcription regulator containing HTH domain
D1Y71_RS27975	COG1475	DNA binding
D1Y71_RS28260	COG1475	DNA binding
D1Y71_RS28525	COG4372	Transposase
D1Y71_RS28530	COG3436	PFAM IS66 Orf2 family protein