locus-tag	class	description
GTK58_RS00020	COG0187	DNA topoisomerase II activity
GTK58_RS00025	COG0561	phosphatase activity
GTK58_RS00040	COG2186	Transcriptional regulator
GTK58_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
GTK58_RS00050	COG0800	Aldolase
GTK58_RS00060	COG3039	Transposase
GTK58_RS00070	COG2271	Major facilitator Superfamily
GTK58_RS00075	COG0823	Involved in the tonB-independent uptake of proteins
GTK58_RS00080	COG5645	(Lipo)protein
GTK58_RS00095	COG3645	SOS response
GTK58_RS00105	COG2188	Transcriptional regulator
GTK58_RS00120	COG2149	membrane
GTK58_RS00140	COG2610	gluconate transmembrane transporter activity
GTK58_RS00145	COG0583	DNA-binding transcription factor activity
GTK58_RS00150	COG2814	Major facilitator Superfamily
GTK58_RS00175	COG0028	Belongs to the TPP enzyme family
GTK58_RS00180	COG0440	acetolactate synthase activity
GTK58_RS00185	COG2197	response regulator
GTK58_RS00195	COG2271	Major facilitator Superfamily
GTK58_RS00235	COG2188	Transcriptional regulator
GTK58_RS00260	COG4580	involved in the transport of maltose and maltodextrins
GTK58_RS00265	COG1447	Phosphotransferase system cellobiose-specific component IIA
GTK58_RS00270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS00270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS00280	COG1609	Transcriptional regulator
GTK58_RS00290	COG3384	dioxygenase
GTK58_RS00295	COG0583	DNA-binding transcription factor activity
GTK58_RS00300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GTK58_RS00305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GTK58_RS00310	COG2828	Protein conserved in bacteria
GTK58_RS00325	COG0697	spore germination
GTK58_RS00330	COG1263	PTS System
GTK58_RS00330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTK58_RS00340	COG2814	Major facilitator Superfamily
GTK58_RS00345	COG1538	Outer membrane efflux protein
GTK58_RS00350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTK58_RS00375	COG0583	DNA-binding transcription factor activity
GTK58_RS00400	COG1464	Belongs to the NlpA lipoprotein family
GTK58_RS00415	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GTK58_RS00425	COG1064	alcohol dehydrogenase
GTK58_RS00455	COG2211	Major facilitator Superfamily
GTK58_RS00460	COG1501	Belongs to the glycosyl hydrolase 31 family
GTK58_RS00470	COG1486	melibiose metabolic process
GTK58_RS00475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTK58_RS00475	COG1263	PTS System
GTK58_RS00480	COG2982	Protein involved in outer membrane biogenesis
GTK58_RS00485	COG2233	PERMEase
GTK58_RS00490	COG0786	glutamate:sodium symporter activity
GTK58_RS00510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GTK58_RS00535	COG3152	Membrane
GTK58_RS00545	COG1494	fructose-1,6-bisphosphatase
GTK58_RS00550	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GTK58_RS00555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTK58_RS00560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GTK58_RS00580	COG2860	membrane
GTK58_RS00590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GTK58_RS00590	COG2169	Transcriptional regulator
GTK58_RS00595	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GTK58_RS00600	COG1561	YicC-like family, N-terminal region
GTK58_RS00605	COG3039	Transposase
GTK58_RS00620	COG1131	(ABC) transporter
GTK58_RS00625	COG0842	Transport permease protein
GTK58_RS00650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GTK58_RS00685	COG1519	Transferase
GTK58_RS00690	COG1216	Glycosyl transferase, family 2
GTK58_RS00695	COG0438	transferase activity, transferring glycosyl groups
GTK58_RS00705	COG0859	PFAM glycosyl transferase family 9
GTK58_RS00730	COG0859	PFAM glycosyl transferase family 9
GTK58_RS00745	COG0156	8-amino-7-oxononanoate synthase activity
GTK58_RS00755	COG0463	Glycosyl transferase, family 2
GTK58_RS00760	COG2861	carbohydrate metabolic process
GTK58_RS00765	COG4942	peptidase
GTK58_RS00775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GTK58_RS00780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GTK58_RS00800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GTK58_RS00810	COG2186	Transcriptional regulator
GTK58_RS00830	COG3722	fumarate hydratase activity
GTK58_RS00850	COG1566	PFAM secretion protein HlyD family protein
GTK58_RS00855	COG0625	glutathione transferase activity
GTK58_RS00865	COG3276	selenocysteine insertion sequence binding
GTK58_RS00870	COG1414	Transcriptional regulator
GTK58_RS00875	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GTK58_RS00880	COG3977	Valine--pyruvate aminotransferase
GTK58_RS00885	COG0366	Alpha amylase catalytic
GTK58_RS00890	COG2992	FlgJ-related protein
GTK58_RS00895	COG2207	Transcriptional regulator
GTK58_RS00895	COG1609	Transcriptional regulator
GTK58_RS00900	COG4214	carbohydrate transport
GTK58_RS00905	COG1129	ABC transporter
GTK58_RS00910	COG4213	ABC transporter substrate-binding protein
GTK58_RS00925	COG4682	membrane
GTK58_RS00930	COG4682	membrane
GTK58_RS00935	COG3274	enterobacterial common antigen metabolic process
GTK58_RS00970	COG1278	Cold shock
GTK58_RS00975	COG2944	sequence-specific DNA binding
GTK58_RS00980	COG2814	Major facilitator Superfamily
GTK58_RS01000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTK58_RS01010	COG1609	Transcriptional regulator
GTK58_RS01015	COG2885	chlorophyll binding
GTK58_RS01020	COG0243	molybdopterin cofactor binding
GTK58_RS01025	COG0456	acetyltransferase
GTK58_RS01030	COG2818	Glycosylase
GTK58_RS01035	COG5571	outer membrane autotransporter
GTK58_RS01040	COG2223	nitrite transmembrane transporter activity
GTK58_RS01070	COG0747	negative chemotaxis
GTK58_RS01075	COG0601	transmembrane transport
GTK58_RS01080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTK58_RS01085	COG0444	Belongs to the ABC transporter superfamily
GTK58_RS01090	COG4608	Belongs to the ABC transporter superfamily
GTK58_RS01110	COG1215	transferase activity, transferring glycosyl groups
GTK58_RS01115	COG0457	Tetratricopeptide repeat
GTK58_RS01130	COG2194	sulfuric ester hydrolase activity
GTK58_RS01160	COG1215	transferase activity, transferring glycosyl groups
GTK58_RS01165	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GTK58_RS01170	COG3118	belongs to the thioredoxin family
GTK58_RS01170	COG0457	Tetratricopeptide repeat
GTK58_RS01175	COG2200	EAL domain
GTK58_RS01175	COG2199	diguanylate cyclase activity
GTK58_RS01185	COG0612	Peptidase, M16
GTK58_RS01200	COG2982	Protein involved in outer membrane biogenesis
GTK58_RS01205	COG0477	Major facilitator Superfamily
GTK58_RS01210	COG1295	ribonuclease BN
GTK58_RS01215	COG0583	DNA-binding transcription factor activity
GTK58_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS01225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTK58_RS01235	COG1454	alcohol dehydrogenase
GTK58_RS01245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTK58_RS01250	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GTK58_RS01255	COG0671	phosphoesterase, PA-phosphatase related
GTK58_RS01275	COG0589	response to stress
GTK58_RS01285	COG0306	phosphate transporter
GTK58_RS01290	COG2081	HI0933 family
GTK58_RS01295	COG2239	Acts as a magnesium transporter
GTK58_RS01305	COG1124	(ABC) transporter
GTK58_RS01315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTK58_RS01320	COG0601	transmembrane transport
GTK58_RS01325	COG0747	negative chemotaxis
GTK58_RS01335	COG3479	Phenolic acid decarboxylase
GTK58_RS01375	COG0628	permease
GTK58_RS01380	COG0477	Major facilitator Superfamily
GTK58_RS01390	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GTK58_RS01405	COG3714	YhhN family
GTK58_RS01415	COG3776	membrane
GTK58_RS01420	COG0742	ribosomal rna small subunit methyltransferase
GTK58_RS01425	COG0552	protein localization to endoplasmic reticulum
GTK58_RS01430	COG2884	Cell division ATP-binding protein ftsE
GTK58_RS01435	COG2177	Part of the ABC transporter FtsEX involved in
GTK58_RS01450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GTK58_RS01460	COG0683	leucine binding
GTK58_RS01475	COG0683	leucine binding
GTK58_RS01480	COG0559	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS01490	COG0411	ABC transporter
GTK58_RS01495	COG0410	ABC transporter
GTK58_RS01510	COG1653	transport
GTK58_RS01530	COG0584	glycerophosphoryl diester phosphodiesterase
GTK58_RS01540	COG0405	Gamma-glutamyltransferase
GTK58_RS01545	COG1247	-acetyltransferase
GTK58_RS01555	COG0673	inositol 2-dehydrogenase activity
GTK58_RS01560	COG1741	Belongs to the pirin family
GTK58_RS01565	COG1609	Transcriptional regulator
GTK58_RS01570	COG3265	gluconokinase activity
GTK58_RS01575	COG2610	gluconate transmembrane transporter activity
GTK58_RS01585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GTK58_RS01610	COG0058	SHG alpha-glucan phosphorylase activity
GTK58_RS01625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GTK58_RS01640	COG1349	DNA-binding transcription factor activity
GTK58_RS01650	COG0058	SHG alpha-glucan phosphorylase activity
GTK58_RS01655	COG1640	4-alpha-glucanotransferase
GTK58_RS01660	COG2610	gluconate transmembrane transporter activity
GTK58_RS01670	COG1040	competence protein
GTK58_RS01695	COG1918	ferrous iron import across plasma membrane
GTK58_RS01700	COG2183	response to ionizing radiation
GTK58_RS01705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GTK58_RS01710	COG0745	RESPONSE REGULATOR receiver
GTK58_RS01730	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GTK58_RS01735	COG1011	Hydrolase
GTK58_RS01745	COG0494	nUDIX hydrolase
GTK58_RS01750	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GTK58_RS01775	COG4796	Type ii and iii secretion system protein
GTK58_RS01790	COG3266	domain, Protein
GTK58_RS01795	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GTK58_RS01800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GTK58_RS01820	COG2146	nitrite reductase [NAD(P)H] activity
GTK58_RS01825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GTK58_RS01830	COG0402	S-adenosylhomocysteine deaminase activity
GTK58_RS01835	COG0738	Major facilitator superfamily
GTK58_RS01860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GTK58_RS01865	COG1289	transmembrane transporter activity
GTK58_RS01875	COG1765	OsmC-like protein
GTK58_RS01880	COG3954	Phosphoribulokinase
GTK58_RS01890	COG0429	hydrolase of the alpha beta-hydrolase fold
GTK58_RS01895	COG0488	(ABC) transporter
GTK58_RS01910	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GTK58_RS01915	COG1047	Peptidyl-prolyl cis-trans
GTK58_RS01925	COG0545	Peptidyl-prolyl cis-trans isomerase
GTK58_RS01930	COG2964	Protein conserved in bacteria
GTK58_RS01970	COG2906	2 iron, 2 sulfur cluster binding
GTK58_RS01995	COG0051	transcription antitermination factor activity, RNA binding
GTK58_RS02030	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GTK58_RS02035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GTK58_RS02100	COG0201	protein transport
GTK58_RS02125	COG0202	RNA polymerase activity
GTK58_RS02140	COG0789	Transcriptional regulator
GTK58_RS02145	COG3036	rescue of stalled ribosome
GTK58_RS02155	COG0569	domain protein
GTK58_RS02175	COG0758	DNA mediated transformation
GTK58_RS02185	COG0551	DNA topoisomerase type I activity
GTK58_RS02205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GTK58_RS02240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTK58_RS02245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTK58_RS02250	COG1309	transcriptional regulator
GTK58_RS02255	COG0582	viral genome integration into host DNA
GTK58_RS02270	COG3561	AntA/AntB antirepressor
GTK58_RS02350	COG1802	Transcriptional regulator
GTK58_RS02350	COG4626	Terminase
GTK58_RS02375	COG4145	pantothenate transmembrane transporter activity
GTK58_RS02380	COG3924	membrane
GTK58_RS02385	COG0439	Biotin carboxylase
GTK58_RS02390	COG0511	ligase activity, forming carbon-carbon bonds
GTK58_RS02405	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GTK58_RS02415	COG2200	EAL domain
GTK58_RS02415	COG2199	diguanylate cyclase activity
GTK58_RS02420	COG1077	Cell shape determining protein MreB Mrl
GTK58_RS02425	COG1792	Involved in formation and maintenance of cell shape
GTK58_RS02430	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GTK58_RS02440	COG1530	ribonuclease E activity
GTK58_RS02445	COG3164	Protein of unknown function
GTK58_RS02450	COG0312	modulator of DNA gyrase
GTK58_RS02455	COG0583	DNA-binding transcription factor activity
GTK58_RS02470	COG1289	transmembrane transporter activity
GTK58_RS02475	COG2732	(Barnase) inhibitor
GTK58_RS02500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GTK58_RS02505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GTK58_RS02510	COG3105	Protein conserved in bacteria
GTK58_RS02515	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GTK58_RS02535	COG0625	glutathione transferase activity
GTK58_RS02540	COG2969	positive regulation of protein catabolic process
GTK58_RS02550	COG0493	'glutamate synthase
GTK58_RS02555	COG0067	glutamate synthase
GTK58_RS02555	COG0070	glutamate synthase
GTK58_RS02555	COG0069	glutamate synthase activity
GTK58_RS02560	COG1242	4 iron, 4 sulfur cluster binding
GTK58_RS02565	COG2271	Major facilitator Superfamily
GTK58_RS02570	COG1063	alcohol dehydrogenase
GTK58_RS02575	COG1312	Catalyzes the dehydration of D-mannonate
GTK58_RS02580	COG0784	Response regulator, receiver
GTK58_RS02580	COG5002	protein histidine kinase activity
GTK58_RS02580	COG2198	Histidine kinase
GTK58_RS02585	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GTK58_RS02590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GTK58_RS02595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS02605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS02610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GTK58_RS02615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GTK58_RS02620	COG1137	ATPase activity
GTK58_RS02625	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GTK58_RS02630	COG3117	lipopolysaccharide transmembrane transporter activity
GTK58_RS02635	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GTK58_RS02645	COG0530	calcium, potassium:sodium antiporter activity
GTK58_RS02650	COG1127	ABC transporter
GTK58_RS02655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GTK58_RS02660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GTK58_RS02665	COG2854	intermembrane phospholipid transfer
GTK58_RS02670	COG3113	response to antibiotic
GTK58_RS02675	COG5007	Belongs to the BolA IbaG family
GTK58_RS02685	COG3423	Transcriptional regulator
GTK58_RS02690	COG0142	geranyltranstransferase activity
GTK58_RS02705	COG0697	spore germination
GTK58_RS02715	COG2027	D-alanyl-D-alanine carboxypeptidase
GTK58_RS02720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GTK58_RS02725	COG1534	Rna-binding protein
GTK58_RS02735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GTK58_RS02740	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GTK58_RS02750	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GTK58_RS02790	COG0195	Participates in both transcription termination and antitermination
GTK58_RS02835	COG0814	amino acid
GTK58_RS02840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GTK58_RS02860	COG3153	acetyltransferase
GTK58_RS02875	COG0693	protein deglycase activity
GTK58_RS02880	COG0702	epimerase
GTK58_RS02885	COG0701	Predicted permease
GTK58_RS02890	COG2823	Periplasmic or secreted lipoprotein
GTK58_RS02910	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GTK58_RS02925	COG1063	alcohol dehydrogenase
GTK58_RS02930	COG3775	system Galactitol-specific IIC component
GTK58_RS02935	COG3414	Phosphotransferase system galactitol-specific IIB component
GTK58_RS02940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS02950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS02950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS02955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS02955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTK58_RS02955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTK58_RS02960	COG1105	Belongs to the carbohydrate kinase PfkB family
GTK58_RS02970	COG1349	DNA-binding transcription factor activity
GTK58_RS02975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTK58_RS02980	COG2721	sulfolactate sulfo-lyase activity
GTK58_RS02990	COG2271	Major facilitator Superfamily
GTK58_RS03000	COG2084	Dehydrogenase
GTK58_RS03005	COG1929	Belongs to the glycerate kinase type-1 family
GTK58_RS03025	COG1741	Belongs to the pirin family
GTK58_RS03030	COG0583	DNA-binding transcription factor activity
GTK58_RS03035	COG3152	Membrane
GTK58_RS03040	COG0435	Glutathione S-transferase
GTK58_RS03045	COG2259	Doxx family
GTK58_RS03055	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GTK58_RS03060	COG4575	ribosome binding
GTK58_RS03065	COG1422	Protein of unknown function (DUF1090)
GTK58_RS03075	COG0586	Pfam SNARE associated Golgi protein
GTK58_RS03080	COG2186	Transcriptional regulator
GTK58_RS03085	COG2271	Major facilitator Superfamily
GTK58_RS03095	COG2721	sulfolactate sulfo-lyase activity
GTK58_RS03110	COG0861	Integral membrane protein TerC family
GTK58_RS03115	COG0673	inositol 2-dehydrogenase activity
GTK58_RS03120	COG1451	nucleotide metabolic process
GTK58_RS03140	COG0446	pyridine nucleotide-disulphide oxidoreductase
GTK58_RS03140	COG1902	pentaerythritol trinitrate reductase activity
GTK58_RS03190	COG1695	Transcriptional regulator
GTK58_RS03195	COG2375	cellular response to nickel ion
GTK58_RS03210	COG1461	Dihydroxyacetone kinase
GTK58_RS03215	COG2376	Dihydroxyacetone kinase
GTK58_RS03285	COG3247	response to pH
GTK58_RS03295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTK58_RS03295	COG2205	protein histidine kinase activity
GTK58_RS03295	COG0784	Response regulator, receiver
GTK58_RS03295	COG2198	Histidine kinase
GTK58_RS03300	COG2197	response regulator
GTK58_RS03325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GTK58_RS03330	COG0358	DNA primase activity
GTK58_RS03400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GTK58_RS03415	COG4991	sh3 domain protein
GTK58_RS03420	COG3025	triphosphatase activity
GTK58_RS03440	COG2960	long-chain fatty acid transporting porin activity
GTK58_RS03455	COG3384	dioxygenase
GTK58_RS03460	COG0754	glutathionylspermidine amidase activity
GTK58_RS03475	COG0494	nUDIX hydrolase
GTK58_RS03480	COG3151	Protein conserved in bacteria
GTK58_RS03485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GTK58_RS03490	COG3150	esterase
GTK58_RS03495	COG0187	DNA topoisomerase II activity
GTK58_RS03500	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GTK58_RS03505	COG2249	NAD(P)H dehydrogenase (quinone) activity
GTK58_RS03510	COG0642	Histidine kinase
GTK58_RS03515	COG0745	RESPONSE REGULATOR receiver
GTK58_RS03520	COG3111	PFAM Bacterial OB fold (BOF) protein
GTK58_RS03525	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GTK58_RS03530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GTK58_RS03535	COG0204	Acyl-transferase
GTK58_RS03540	COG2132	Multicopper oxidase
GTK58_RS03545	COG1032	radical SAM domain protein
GTK58_RS03555	COG0656	L-ascorbic acid biosynthetic process
GTK58_RS03560	COG1979	alcohol dehydrogenase
GTK58_RS03565	COG2207	Transcriptional regulator
GTK58_RS03570	COG0586	Pfam SNARE associated Golgi protein
GTK58_RS03575	COG0626	cystathionine gamma-synthase activity
GTK58_RS03585	COG0811	peptide transport
GTK58_RS03590	COG0848	biopolymer transport protein
GTK58_RS03595	COG2211	Major facilitator Superfamily
GTK58_RS03620	COG0625	glutathione transferase activity
GTK58_RS03635	COG0754	glutathionylspermidine amidase activity
GTK58_RS03640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTK58_RS03660	COG0583	DNA-binding transcription factor activity
GTK58_RS03665	COG0626	cystathionine gamma-synthase activity
GTK58_RS03715	COG0305	Participates in initiation and elongation during chromosome replication
GTK58_RS03925	COG3423	Transcriptional regulator
GTK58_RS03935	COG1278	Cold shock
GTK58_RS03940	COG3423	Transcriptional regulator
GTK58_RS04000	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GTK58_RS04010	COG1811	Na channel or pump
GTK58_RS04015	COG1982	Orn Lys Arg decarboxylase major
GTK58_RS04020	COG2211	Major facilitator Superfamily
GTK58_RS04035	COG1194	a g-specific adenine glycosylase
GTK58_RS04045	COG3171	Protein conserved in bacteria
GTK58_RS04055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GTK58_RS04070	COG0762	integral membrane protein
GTK58_RS04075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GTK58_RS04080	COG2805	Type II/IV secretion system protein
GTK58_RS04100	COG0189	ligase activity
GTK58_RS04105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GTK58_RS04110	COG2356	endonuclease I
GTK58_RS04120	COG2814	Major facilitator Superfamily
GTK58_RS04160	COG2146	nitrite reductase [NAD(P)H] activity
GTK58_RS04175	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS04180	COG1414	Transcriptional regulator
GTK58_RS04210	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS04215	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
GTK58_RS04235	COG3039	Transposase
GTK58_RS04240	COG0501	Belongs to the peptidase M48B family
GTK58_RS04245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GTK58_RS04260	COG0191	fructose-bisphosphate aldolase activity
GTK58_RS04265	COG0668	transmembrane transport
GTK58_RS04275	COG2968	Membrane
GTK58_RS04290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GTK58_RS04295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GTK58_RS04315	COG0006	proline dipeptidase activity
GTK58_RS04320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTK58_RS04325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTK58_RS04345	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS04350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GTK58_RS04370	COG2723	6-phospho-beta-galactosidase activity
GTK58_RS04375	COG1737	Transcriptional regulator
GTK58_RS04385	COG1272	protein, Hemolysin III
GTK58_RS04395	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GTK58_RS04405	COG0716	FMN binding
GTK58_RS04410	COG4974	Belongs to the 'phage' integrase family
GTK58_RS04420	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GTK58_RS04440	COG4942	peptidase
GTK58_RS04450	COG2814	Major facilitator Superfamily
GTK58_RS04465	COG0667	Aldo Keto reductase
GTK58_RS04500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GTK58_RS04505	COG1393	Belongs to the ArsC family
GTK58_RS04510	COG3104	oligopeptide transport
GTK58_RS04520	COG1538	Outer membrane efflux protein
GTK58_RS04525	COG1289	transmembrane transporter activity
GTK58_RS04540	COG3592	Divergent 4Fe-4S mono-cluster
GTK58_RS04545	COG2388	GCN5-related N-acetyl-transferase
GTK58_RS04555	COG3539	Fimbrial protein
GTK58_RS04560	COG3539	Fimbrial protein
GTK58_RS04565	COG3539	Fimbrial protein
GTK58_RS04570	COG3188	usher protein
GTK58_RS04575	COG3121	Chaperone
GTK58_RS04580	COG3539	Fimbrial protein
GTK58_RS04590	COG4974	Belongs to the 'phage' integrase family
GTK58_RS04595	COG0582	viral genome integration into host DNA
GTK58_RS04600	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GTK58_RS04605	COG1846	Transcriptional regulator
GTK58_RS04610	COG0697	spore germination
GTK58_RS04660	COG0667	Aldo Keto reductase
GTK58_RS04665	COG0814	amino acid
GTK58_RS04680	COG0183	Belongs to the thiolase family
GTK58_RS04685	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GTK58_RS04690	COG0823	Involved in the tonB-independent uptake of proteins
GTK58_RS04695	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS04700	COG2814	Major facilitator Superfamily
GTK58_RS04730	COG3842	ATPase activity
GTK58_RS04735	COG0395	ABC-type sugar transport system, permease component
GTK58_RS04740	COG1175	transmembrane transport
GTK58_RS04745	COG1917	Cupin 2, conserved barrel domain protein
GTK58_RS04750	COG1794	racemase activity, acting on amino acids and derivatives
GTK58_RS04755	COG0583	DNA-binding transcription factor activity
GTK58_RS04760	COG0019	diaminopimelate decarboxylase activity
GTK58_RS04765	COG1609	Transcriptional regulator
GTK58_RS04770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS04775	COG2723	6-phospho-beta-galactosidase activity
GTK58_RS04780	COG2186	Transcriptional regulator
GTK58_RS04790	COG1609	Transcriptional regulator
GTK58_RS04805	COG0667	Aldo Keto reductase
GTK58_RS04815	COG0861	Integral membrane protein TerC family
GTK58_RS04845	COG2165	general secretion pathway protein
GTK58_RS04850	COG4795	General secretion pathway protein
GTK58_RS04860	COG4967	type IV pilus modification protein PilV
GTK58_RS04865	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GTK58_RS04870	COG1025	Belongs to the peptidase M16 family
GTK58_RS04875	COG1074	ATP-dependent DNA helicase activity
GTK58_RS04880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GTK58_RS04890	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GTK58_RS04890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GTK58_RS04895	COG0860	N-Acetylmuramoyl-L-alanine amidase
GTK58_RS04900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GTK58_RS04920	COG4810	utilization protein
GTK58_RS04930	COG4656	Part of a membrane complex involved in electron transport
GTK58_RS04935	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS04935	COG1454	alcohol dehydrogenase
GTK58_RS04970	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GTK58_RS05005	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GTK58_RS05040	COG2241	protein methyltransferase activity
GTK58_RS05050	COG2875	Belongs to the precorrin methyltransferase family
GTK58_RS05130	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GTK58_RS05135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GTK58_RS05140	COG2166	iron-sulfur cluster assembly
GTK58_RS05145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GTK58_RS05155	COG0583	DNA-binding transcription factor activity
GTK58_RS05160	COG2363	Small membrane protein
GTK58_RS05170	COG1349	DNA-binding transcription factor activity
GTK58_RS05190	COG0738	Major facilitator superfamily
GTK58_RS05195	COG0235	Class ii aldolase
GTK58_RS05200	COG1454	alcohol dehydrogenase
GTK58_RS05215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GTK58_RS05230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GTK58_RS05235	COG2011	ABC-type metal ion transport system permease component
GTK58_RS05240	COG1464	Belongs to the NlpA lipoprotein family
GTK58_RS05245	COG0477	Major facilitator Superfamily
GTK58_RS05255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GTK58_RS05260	COG1760	l-serine dehydratase
GTK58_RS05265	COG0814	amino acid
GTK58_RS05270	COG1611	Belongs to the LOG family
GTK58_RS05285	COG3098	single-species biofilm formation
GTK58_RS05290	COG0564	pseudouridine synthase activity
GTK58_RS05295	COG0716	FMN binding
GTK58_RS05300	COG2271	Major facilitator Superfamily
GTK58_RS05305	COG4948	Mandelate Racemase Muconate Lactonizing
GTK58_RS05310	COG4948	Mandelate Racemase Muconate Lactonizing
GTK58_RS05315	COG1929	Belongs to the glycerate kinase type-1 family
GTK58_RS05325	COG4999	Histidine kinase
GTK58_RS05325	COG3850	Histidine kinase
GTK58_RS05325	COG3437	response regulator, receiver
GTK58_RS05325	COG2205	protein histidine kinase activity
GTK58_RS05335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GTK58_RS05340	COG3956	TIGRFAM MazG family protein
GTK58_RS05360	COG0602	queuosine metabolic process
GTK58_RS05365	COG0720	synthase
GTK58_RS05385	COG2234	aminopeptidase activity
GTK58_RS05445	COG1388	LysM domain
GTK58_RS05445	COG4942	peptidase
GTK58_RS05450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GTK58_RS05475	COG0163	prenyltransferase activity
GTK58_RS05480	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GTK58_RS05520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTK58_RS05525	COG4558	Periplasmic binding protein
GTK58_RS05530	COG3720	iron ion transport
GTK58_RS05550	COG0679	Auxin Efflux Carrier
GTK58_RS05565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GTK58_RS05570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GTK58_RS05575	COG1121	(ABC) transporter
GTK58_RS05580	COG0803	Belongs to the bacterial solute-binding protein 9 family
GTK58_RS05585	COG1609	Transcriptional regulator
GTK58_RS05590	COG1940	carbohydrate kinase activity
GTK58_RS05595	COG1447	Phosphotransferase system cellobiose-specific component IIA
GTK58_RS05600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS05605	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS05610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS05615	COG4580	involved in the transport of maltose and maltodextrins
GTK58_RS05625	COG2723	6-phospho-beta-galactosidase activity
GTK58_RS05635	COG0309	Hydrogenase expression formation protein (HypE)
GTK58_RS05640	COG0409	Hydrogenase expression formation protein
GTK58_RS05645	COG0298	carbon dioxide binding
GTK58_RS05650	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GTK58_RS05665	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GTK58_RS05670	COG0651	ATP synthesis coupled electron transport
GTK58_RS05675	COG0650	Formate hydrogenlyase subunit 4
GTK58_RS05680	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GTK58_RS05680	COG3261	NADH dehydrogenase
GTK58_RS05685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTK58_RS05690	COG3260	NADH ubiquinone oxidoreductase 20
GTK58_RS05700	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GTK58_RS05710	COG2723	6-phospho-beta-galactosidase activity
GTK58_RS05715	COG1263	PTS System
GTK58_RS05715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTK58_RS05720	COG1609	Transcriptional regulator
GTK58_RS05725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GTK58_RS05730	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GTK58_RS05735	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GTK58_RS05760	COG1349	DNA-binding transcription factor activity
GTK58_RS05765	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS05780	COG3732	PTS system glucitol sorbitol-specific
GTK58_RS05785	COG3730	PTS system glucitol sorbitol-specific
GTK58_RS05790	COG2951	lytic endotransglycosylase activity
GTK58_RS05800	COG1121	(ABC) transporter
GTK58_RS05805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GTK58_RS05810	COG0803	Belongs to the bacterial solute-binding protein 9 family
GTK58_RS05815	COG1546	Belongs to the CinA family
GTK58_RS05865	COG2823	Periplasmic or secreted lipoprotein
GTK58_RS05870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTK58_RS05875	COG1238	metal cluster binding
GTK58_RS05895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GTK58_RS05900	COG2814	Major facilitator Superfamily
GTK58_RS05905	COG1566	PFAM secretion protein HlyD family protein
GTK58_RS05910	COG1846	Transcriptional regulator
GTK58_RS05920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GTK58_RS05930	COG4176	ABC-type proline glycine betaine transport system permease component
GTK58_RS05945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GTK58_RS05955	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GTK58_RS05960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GTK58_RS05965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTK58_RS05970	COG4575	ribosome binding
GTK58_RS05985	COG2916	Histone family protein nucleoid-structuring protein H-NS
GTK58_RS06000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GTK58_RS06005	COG0640	Transcriptional regulator
GTK58_RS06015	COG0583	DNA-binding transcription factor activity
GTK58_RS06020	COG3284	Transcriptional regulator
GTK58_RS06025	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS06030	COG3539	Fimbrial protein
GTK58_RS06035	COG3039	Transposase
GTK58_RS06040	COG4974	Belongs to the 'phage' integrase family
GTK58_RS06075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GTK58_RS06090	COG3344	reverse transcriptase
GTK58_RS06125	COG4695	Portal protein
GTK58_RS06285	COG2867	negative regulation of translational initiation
GTK58_RS06300	COG0497	DNA recombination
GTK58_RS06315	COG4536	flavin adenine dinucleotide binding
GTK58_RS06320	COG4137	Cytochrome C assembly protein
GTK58_RS06325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GTK58_RS06360	COG2885	chlorophyll binding
GTK58_RS06365	COG2199	diguanylate cyclase activity
GTK58_RS06375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GTK58_RS06380	COG0287	Prephenate dehydrogenase
GTK58_RS06380	COG1605	Chorismate mutase
GTK58_RS06390	COG1605	Chorismate mutase
GTK58_RS06390	COG0077	Prephenate dehydratase
GTK58_RS06400	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GTK58_RS06405	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTK58_RS06410	COG0564	pseudouridine synthase activity
GTK58_RS06420	COG0542	response to heat
GTK58_RS06450	COG0656	L-ascorbic acid biosynthetic process
GTK58_RS06455	COG0583	DNA-binding transcription factor activity
GTK58_RS06460	COG2814	Major facilitator Superfamily
GTK58_RS06470	COG2226	methyltransferase
GTK58_RS06475	COG0741	lytic transglycosylase activity
GTK58_RS06475	COG1388	LysM domain
GTK58_RS06485	COG2226	methyltransferase
GTK58_RS06495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GTK58_RS06505	COG0583	DNA-binding transcription factor activity
GTK58_RS06515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GTK58_RS06520	COG1960	acyl-CoA dehydrogenase activity
GTK58_RS06530	COG0121	glutamine amidotransferase
GTK58_RS06535	COG3034	peptidoglycan biosynthetic process
GTK58_RS06550	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GTK58_RS06555	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GTK58_RS06570	COG2991	Protein conserved in bacteria
GTK58_RS06585	COG0454	-acetyltransferase
GTK58_RS06590	COG2195	Cleaves the N-terminal amino acid of tripeptides
GTK58_RS06610	COG1802	Transcriptional regulator
GTK58_RS06615	COG1113	amino acid transport
GTK58_RS06620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GTK58_RS06625	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS06630	COG0579	oxidoreductase
GTK58_RS06645	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GTK58_RS06650	COG0625	glutathione transferase activity
GTK58_RS06655	COG3775	system Galactitol-specific IIC component
GTK58_RS06660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GTK58_RS06665	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS06670	COG1070	Carbohydrate kinase
GTK58_RS06680	COG1830	Aldolase
GTK58_RS06690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTK58_RS06695	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTK58_RS06700	COG0022	dehydrogenase e1 component
GTK58_RS06705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GTK58_RS06765	COG1192	Involved in chromosome partitioning
GTK58_RS06770	COG0582	viral genome integration into host DNA
GTK58_RS06795	COG0791	NLP P60 protein
GTK58_RS06815	COG3639	organic phosphonate transmembrane transporter activity
GTK58_RS06825	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GTK58_RS06850	COG3188	usher protein
GTK58_RS06865	COG0765	amino acid transport
GTK58_RS06870	COG0765	amino acid transport
GTK58_RS06875	COG1126	abc transporter atp-binding protein
GTK58_RS06880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTK58_RS06890	COG0410	ABC transporter
GTK58_RS06895	COG0411	ABC transporter
GTK58_RS06915	COG4302	ethanolamine ammonia-lyase activity
GTK58_RS06920	COG4303	Ethanolamine ammonia lyase large subunit
GTK58_RS06930	COG0833	amino acid
GTK58_RS06935	COG2040	homocysteine
GTK58_RS06940	COG4521	taurine ABC transporter
GTK58_RS06945	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GTK58_RS06950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTK58_RS06955	COG2175	clavaminate synthase activity
GTK58_RS06965	COG0113	porphobilinogen synthase activity
GTK58_RS06970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GTK58_RS06975	COG1335	isochorismatase
GTK58_RS06980	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GTK58_RS07000	COG1181	Belongs to the D-alanine--D-alanine ligase family
GTK58_RS07020	COG1785	Belongs to the alkaline phosphatase family
GTK58_RS07030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GTK58_RS07040	COG3416	Protein conserved in bacteria
GTK58_RS07045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GTK58_RS07055	COG4126	flavin adenine dinucleotide binding
GTK58_RS07070	COG1940	carbohydrate kinase activity
GTK58_RS07075	COG0419	ATPase involved in DNA repair
GTK58_RS07080	COG0420	3'-5' exonuclease activity
GTK58_RS07095	COG1114	Component of the transport system for branched-chain amino acids
GTK58_RS07105	COG0366	Alpha amylase catalytic
GTK58_RS07110	COG0583	DNA-binding transcription factor activity
GTK58_RS07115	COG1335	isochorismatase
GTK58_RS07125	COG1228	amidohydrolase
GTK58_RS07135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTK58_RS07150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS07155	COG0450	alkyl hydroperoxide reductase
GTK58_RS07175	COG1862	Preprotein translocase
GTK58_RS07180	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTK58_RS07185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTK58_RS07205	COG4238	major outer membrane lipoprotein
GTK58_RS07215	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GTK58_RS07215	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GTK58_RS07235	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GTK58_RS07240	COG0667	Aldo Keto reductase
GTK58_RS07250	COG0142	geranyltranstransferase activity
GTK58_RS07270	COG0693	protein deglycase activity
GTK58_RS07275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GTK58_RS07285	COG2814	Major facilitator Superfamily
GTK58_RS07290	COG0673	inositol 2-dehydrogenase activity
GTK58_RS07305	COG1053	succinate dehydrogenase
GTK58_RS07315	COG1053	succinate dehydrogenase
GTK58_RS07320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GTK58_RS07325	COG1414	Transcriptional regulator
GTK58_RS07340	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GTK58_RS07345	COG1845	cytochrome c oxidase, subunit III
GTK58_RS07350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GTK58_RS07355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GTK58_RS07360	COG2223	nitrite transmembrane transporter activity
GTK58_RS07365	COG3056	Lipoprotein
GTK58_RS07370	COG0271	Belongs to the BolA IbaG family
GTK58_RS07395	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GTK58_RS07400	COG0776	regulation of translation
GTK58_RS07405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTK58_RS07410	COG1555	photosystem II stabilization
GTK58_RS07415	COG0824	Thioesterase
GTK58_RS07425	COG4533	DNA binding
GTK58_RS07440	COG1522	sequence-specific DNA binding
GTK58_RS07445	COG1132	(ABC) transporter
GTK58_RS07450	COG1132	(ABC) transporter
GTK58_RS07455	COG0347	Belongs to the P(II) protein family
GTK58_RS07460	COG0004	ammonium transporteR
GTK58_RS07465	COG1946	Acyl-CoA thioesterase
GTK58_RS07470	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GTK58_RS07475	COG3695	enzyme binding
GTK58_RS07505	COG2364	Membrane
GTK58_RS07520	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GTK58_RS07530	COG2182	Extracellular solute-binding protein
GTK58_RS07535	COG1175	transmembrane transport
GTK58_RS07540	COG3833	ABC-type maltose transport systems, permease component
GTK58_RS07545	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GTK58_RS07550	COG1874	Beta-galactosidase
GTK58_RS07595	COG0110	maltose O-acetyltransferase activity
GTK58_RS07610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTK58_RS07615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTK58_RS07620	COG1309	transcriptional regulator
GTK58_RS07625	COG3039	Transposase
GTK58_RS07635	COG3264	Mechanosensitive ion channel
GTK58_RS07635	COG1196	nuclear chromosome segregation
GTK58_RS07640	COG5464	transposase or invertase
GTK58_RS07650	COG3923	Primosomal replication protein n
GTK58_RS07655	COG2832	Protein of unknown function (DUF454)
GTK58_RS07695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTK58_RS07700	COG4651	solute:proton antiporter activity
GTK58_RS07700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GTK58_RS07705	COG2223	nitrite transmembrane transporter activity
GTK58_RS07715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GTK58_RS07720	COG3735	TraB family
GTK58_RS07735	COG1585	Membrane protein implicated in regulation of membrane protease activity
GTK58_RS07740	COG0330	HflC and HflK could
GTK58_RS07745	COG4619	ABC transporter
GTK58_RS07750	COG0390	transport system, permease component
GTK58_RS07755	COG3118	belongs to the thioredoxin family
GTK58_RS07760	COG0300	oxidoreductase activity
GTK58_RS07765	COG2755	lipolytic protein G-D-S-L family
GTK58_RS07770	COG4181	ATPase activity
GTK58_RS07775	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GTK58_RS07790	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GTK58_RS07795	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GTK58_RS07810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GTK58_RS07820	COG2501	S4 domain
GTK58_RS07865	COG3539	Fimbrial protein
GTK58_RS07870	COG3121	Chaperone
GTK58_RS07875	COG3188	usher protein
GTK58_RS07890	COG1560	Kdo2-lipid A biosynthetic process
GTK58_RS07900	COG3710	Transcriptional regulator
GTK58_RS07905	COG0531	amino acid
GTK58_RS07910	COG1982	Orn Lys Arg decarboxylase major
GTK58_RS07915	COG3104	oligopeptide transport
GTK58_RS07945	COG0673	inositol 2-dehydrogenase activity
GTK58_RS07960	COG1129	ABC transporter
GTK58_RS07965	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS08010	COG1566	PFAM secretion protein HlyD family protein
GTK58_RS08015	COG1120	ATPase activity
GTK58_RS08020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTK58_RS08040	COG1473	amidohydrolase
GTK58_RS08045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTK58_RS08050	COG0667	Aldo Keto reductase
GTK58_RS08095	COG0531	amino acid
GTK58_RS08105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GTK58_RS08110	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS08125	COG1113	amino acid transport
GTK58_RS08130	COG2211	Major facilitator Superfamily
GTK58_RS08140	COG0673	inositol 2-dehydrogenase activity
GTK58_RS08150	COG2771	luxR family
GTK58_RS08165	COG3188	usher protein
GTK58_RS08195	COG0668	transmembrane transport
GTK58_RS08200	COG0477	Major facilitator Superfamily
GTK58_RS08215	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GTK58_RS08215	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GTK58_RS08220	COG2222	sugar isomerase
GTK58_RS08225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GTK58_RS08230	COG3716	PTS system mannose fructose sorbose family IID component
GTK58_RS08240	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTK58_RS08250	COG0778	Nitroreductase
GTK58_RS08255	COG2315	Protein conserved in bacteria
GTK58_RS08265	COG3316	Transposase and inactivated derivatives
GTK58_RS08280	COG3698	Phosphodiester glycosidase
GTK58_RS08290	COG0697	spore germination
GTK58_RS08305	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GTK58_RS08310	COG0765	amino acid transport
GTK58_RS08315	COG4215	(ABC) transporter
GTK58_RS08325	COG4221	oxidoreductase activity
GTK58_RS08335	COG4608	Belongs to the ABC transporter superfamily
GTK58_RS08340	COG0444	Belongs to the ABC transporter superfamily
GTK58_RS08345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTK58_RS08350	COG0601	transmembrane transport
GTK58_RS08355	COG0747	negative chemotaxis
GTK58_RS08380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GTK58_RS08390	COG0668	transmembrane transport
GTK58_RS08395	COG0583	DNA-binding transcription factor activity
GTK58_RS08405	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS08415	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS08420	COG1129	ABC transporter
GTK58_RS08430	COG1879	ABC-type sugar transport system periplasmic component
GTK58_RS08435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GTK58_RS08440	COG2390	Transcriptional regulator
GTK58_RS08445	COG3959	Transketolase, thiamine diphosphate binding domain
GTK58_RS08450	COG3958	Transketolase
GTK58_RS08455	COG2977	Belongs to the P-Pant transferase superfamily
GTK58_RS08460	COG4771	TonB-dependent receptor
GTK58_RS08465	COG2382	esterase
GTK58_RS08470	COG3251	PFAM MbtH domain protein
GTK58_RS08475	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GTK58_RS08475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GTK58_RS08480	COG1120	ATPase activity
GTK58_RS08485	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTK58_RS08490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTK58_RS08500	COG4592	Periplasmic binding protein
GTK58_RS08505	COG1169	isochorismate synthase
GTK58_RS08510	COG1021	2,3-dihydroxybenzoate-AMP ligase
GTK58_RS08515	COG1535	isochorismatase
GTK58_RS08515	COG3433	isochorismatase activity
GTK58_RS08520	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS08530	COG1966	Carbon starvation protein
GTK58_RS08535	COG2879	small protein
GTK58_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS08555	COG0371	Dehydrogenase
GTK58_RS08560	COG1129	ABC transporter
GTK58_RS08565	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS08595	COG2271	Major facilitator Superfamily
GTK58_RS08600	COG0483	inositol monophosphate 1-phosphatase activity
GTK58_RS08610	COG0402	S-adenosylhomocysteine deaminase activity
GTK58_RS08620	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GTK58_RS08635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GTK58_RS08645	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS08650	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS08655	COG1129	ABC transporter
GTK58_RS08680	COG0436	Aminotransferase
GTK58_RS08685	COG1475	DNA binding
GTK58_RS08690	COG3969	phosphoadenosine phosphosulfate
GTK58_RS08695	COG0583	DNA-binding transcription factor activity
GTK58_RS08700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GTK58_RS08705	COG0450	alkyl hydroperoxide reductase
GTK58_RS08715	COG0589	response to stress
GTK58_RS08720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GTK58_RS08725	COG3719	Belongs to the RNase T2 family
GTK58_RS08730	COG3069	C4-dicarboxylate transmembrane transporter activity
GTK58_RS08740	COG1278	Cold shock
GTK58_RS08750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GTK58_RS08765	COG0583	DNA-binding transcription factor activity
GTK58_RS08780	COG1686	Belongs to the peptidase S11 family
GTK58_RS08785	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GTK58_RS08790	COG0772	Belongs to the SEDS family
GTK58_RS08795	COG0768	penicillin binding
GTK58_RS08805	COG0799	negative regulation of ribosome biogenesis
GTK58_RS08820	COG1466	dna polymerase III delta subunit
GTK58_RS08835	COG2888	peptidyl-tyrosine sulfation
GTK58_RS08850	COG1126	abc transporter atp-binding protein
GTK58_RS08855	COG0765	amino acid transport
GTK58_RS08860	COG0765	amino acid transport
GTK58_RS08875	COG4535	Mg2 and Co2 transporter CorC
GTK58_RS08885	COG1702	phosphate starvation-inducible protein PhoH
GTK58_RS08895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTK58_RS08935	COG0367	asparagine synthase
GTK58_RS08940	COG0647	UMP catabolic process
GTK58_RS08945	COG1940	carbohydrate kinase activity
GTK58_RS08945	COG1846	Transcriptional regulator
GTK58_RS08950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GTK58_RS08990	COG0735	belongs to the Fur family
GTK58_RS09005	COG0596	Alpha beta hydrolase
GTK58_RS09015	COG0033	Phosphoglucomutase
GTK58_RS09025	COG0745	RESPONSE REGULATOR receiver
GTK58_RS09030	COG2205	protein histidine kinase activity
GTK58_RS09060	COG0415	Belongs to the DNA photolyase family
GTK58_RS09070	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GTK58_RS09075	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GTK58_RS09080	COG1984	allophanate hydrolase subunit 2
GTK58_RS09115	COG2009	succinate dehydrogenase
GTK58_RS09120	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GTK58_RS09125	COG1053	succinate dehydrogenase
GTK58_RS09130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GTK58_RS09135	COG0567	Dehydrogenase, E1 component
GTK58_RS09140	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTK58_RS09150	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GTK58_RS09160	COG1271	oxidase subunit
GTK58_RS09165	COG1294	oxidase, subunit
GTK58_RS09170	COG4890	Cyd operon protein YbgT
GTK58_RS09175	COG3790	cyd operon protein YbgE
GTK58_RS09180	COG0824	Thioesterase
GTK58_RS09185	COG0811	peptide transport
GTK58_RS09190	COG0848	biopolymer transport protein
GTK58_RS09195	COG3064	Membrane
GTK58_RS09205	COG2885	chlorophyll binding
GTK58_RS09210	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GTK58_RS09250	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GTK58_RS09255	COG3201	nicotinamide mononucleotide transporter
GTK58_RS09270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GTK58_RS09280	COG2017	converts alpha-aldose to the beta-anomer
GTK58_RS09290	COG1085	galactose-1-phosphate uridylyltransferase
GTK58_RS09300	COG1119	ATPase activity
GTK58_RS09305	COG2005	Transcriptional regulator
GTK58_RS09305	COG3585	molybdate ion transport
GTK58_RS09315	COG0725	ABC transporter, periplasmic molybdate-binding protein
GTK58_RS09320	COG4149	molybdate abc transporter
GTK58_RS09325	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GTK58_RS09330	COG0561	phosphatase activity
GTK58_RS09355	COG2200	EAL domain
GTK58_RS09360	COG0789	Transcriptional regulator
GTK58_RS09390	COG4677	pectinesterase activity
GTK58_RS09425	COG1881	PFAM PEBP family protein
GTK58_RS09430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GTK58_RS09445	COG2226	methyltransferase
GTK58_RS09455	COG0410	ABC transporter
GTK58_RS09475	COG0642	Histidine kinase
GTK58_RS09480	COG0745	RESPONSE REGULATOR receiver
GTK58_RS09500	COG0521	Mo-molybdopterin cofactor biosynthetic process
GTK58_RS09510	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GTK58_RS09515	COG0314	molybdopterin synthase activity
GTK58_RS09520	COG0670	Belongs to the BI1 family
GTK58_RS09525	COG0392	lysyltransferase activity
GTK58_RS09530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GTK58_RS09535	COG3568	Endonuclease Exonuclease Phosphatase
GTK58_RS09545	COG0842	Transport permease protein
GTK58_RS09550	COG0842	Transport permease protein
GTK58_RS09555	COG1131	(ABC) transporter
GTK58_RS09560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTK58_RS09565	COG1309	transcriptional regulator
GTK58_RS09570	COG0583	DNA-binding transcription factor activity
GTK58_RS09575	COG2271	Major facilitator Superfamily
GTK58_RS09580	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS09585	COG3959	Transketolase, thiamine diphosphate binding domain
GTK58_RS09590	COG3958	Transketolase
GTK58_RS09595	COG0513	Belongs to the DEAD box helicase family
GTK58_RS09600	COG1199	ATP-dependent helicase activity
GTK58_RS09605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GTK58_RS09615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GTK58_RS09625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GTK58_RS09635	COG0668	transmembrane transport
GTK58_RS09640	COG1126	abc transporter atp-binding protein
GTK58_RS09645	COG0765	amino acid transport
GTK58_RS09650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTK58_RS09665	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GTK58_RS09670	COG2194	sulfuric ester hydrolase activity
GTK58_RS09680	COG1321	iron dependent repressor
GTK58_RS09685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GTK58_RS09690	COG2723	6-phospho-beta-galactosidase activity
GTK58_RS09695	COG2188	Transcriptional regulator
GTK58_RS09700	COG1376	ErfK ybiS ycfS ynhG family protein
GTK58_RS09705	COG2365	Tyrosine phosphatase family
GTK58_RS09710	COG0488	(ABC) transporter
GTK58_RS09720	COG2271	Major facilitator Superfamily
GTK58_RS09725	COG1609	Transcriptional regulator
GTK58_RS09735	COG0561	phosphatase activity
GTK58_RS09745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GTK58_RS09750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GTK58_RS09755	COG0303	'Molybdopterin
GTK58_RS09770	COG0747	negative chemotaxis
GTK58_RS09790	COG2223	nitrite transmembrane transporter activity
GTK58_RS09800	COG2133	pyrroloquinoline quinone binding
GTK58_RS09805	COG0625	glutathione transferase activity
GTK58_RS09810	COG1686	Belongs to the peptidase S11 family
GTK58_RS09815	COG1349	DNA-binding transcription factor activity
GTK58_RS09820	COG0671	phosphoesterase, PA-phosphatase related
GTK58_RS09825	COG2814	Major facilitator Superfamily
GTK58_RS09830	COG0561	phosphatase activity
GTK58_RS09835	COG0738	Major facilitator superfamily
GTK58_RS09840	COG3226	Transcriptional regulator
GTK58_RS09845	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GTK58_RS09850	COG3344	reverse transcriptase
GTK58_RS09890	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GTK58_RS09925	COG4695	Portal protein
GTK58_RS09995	COG3039	Transposase
GTK58_RS10090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GTK58_RS10115	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GTK58_RS10120	COG3842	ATPase activity
GTK58_RS10125	COG1176	ABC-type spermidine putrescine transport system, permease component I
GTK58_RS10130	COG1177	transmembrane transport
GTK58_RS10145	COG0745	RESPONSE REGULATOR receiver
GTK58_RS10150	COG5002	protein histidine kinase activity
GTK58_RS10155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTK58_RS10160	COG4160	amino acid transport
GTK58_RS10165	COG4215	(ABC) transporter
GTK58_RS10170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTK58_RS10175	COG1126	abc transporter atp-binding protein
GTK58_RS10180	COG3316	Transposase and inactivated derivatives
GTK58_RS10190	COG5001	Diguanylate cyclase
GTK58_RS10190	COG3706	GGDEF domain
GTK58_RS10190	COG4251	negative regulation of phosphorylation
GTK58_RS10190	COG2203	Gaf domain
GTK58_RS10195	COG3023	N-Acetylmuramoyl-L-alanine amidase
GTK58_RS10200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTK58_RS10205	COG0702	epimerase
GTK58_RS10210	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GTK58_RS10215	COG0028	Belongs to the TPP enzyme family
GTK58_RS10225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GTK58_RS10235	COG2431	L-lysine efflux transmembrane transporter activity
GTK58_RS10240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GTK58_RS10245	COG3593	DNA synthesis involved in DNA repair
GTK58_RS10250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTK58_RS10260	COG1278	Cold shock
GTK58_RS10270	COG0542	response to heat
GTK58_RS10285	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GTK58_RS10290	COG4988	ABC transporter
GTK58_RS10295	COG0492	ferredoxin-NADP+ reductase activity
GTK58_RS10305	COG1674	ftsk spoiiie
GTK58_RS10305	COG1178	ABC-type Fe3 transport system permease component
GTK58_RS10315	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GTK58_RS10325	COG0243	molybdopterin cofactor binding
GTK58_RS10330	COG0437	4 iron, 4 sulfur cluster binding
GTK58_RS10335	COG3302	dmso reductase anchor subunit
GTK58_RS10345	COG0477	Major facilitator Superfamily
GTK58_RS10350	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GTK58_RS10355	COG1882	Formate acetyltransferase
GTK58_RS10360	COG2116	formate transmembrane transporter activity
GTK58_RS10365	COG1944	ATP diphosphatase activity
GTK58_RS10370	COG2323	membrane
GTK58_RS10390	COG0539	negative regulation of cytoplasmic translation
GTK58_RS10400	COG0658	competence protein
GTK58_RS10400	COG2333	competence protein COMEC
GTK58_RS10415	COG3214	Protein conserved in bacteria
GTK58_RS10430	COG3173	Aminoglycoside phosphotransferase
GTK58_RS10435	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GTK58_RS10440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GTK58_RS10450	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GTK58_RS10460	COG2989	Protein conserved in bacteria
GTK58_RS10465	COG3108	Peptidase M15
GTK58_RS10470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GTK58_RS10475	COG1448	Aminotransferase
GTK58_RS10490	COG1522	sequence-specific DNA binding
GTK58_RS10500	COG0814	amino acid
GTK58_RS10510	COG1473	amidohydrolase
GTK58_RS10520	COG0308	aminopeptidase N
GTK58_RS10530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTK58_RS10535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GTK58_RS10540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GTK58_RS10545	COG0431	NADPH-dependent FMN reductase
GTK58_RS10560	COG3217	Mosc domain protein beta barrel domain protein
GTK58_RS10560	COG0633	Ferredoxin
GTK58_RS10570	COG0488	(ABC) transporter
GTK58_RS10575	COG2995	paraquat-inducible protein a
GTK58_RS10580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GTK58_RS10580	COG3008	intermembrane lipid transfer
GTK58_RS10585	COG3009	Protein conserved in bacteria
GTK58_RS10590	COG3130	regulation of translation
GTK58_RS10600	COG1067	ATP-dependent peptidase activity
GTK58_RS10620	COG3070	regulator of competence-specific genes
GTK58_RS10625	COG1289	transmembrane transporter activity
GTK58_RS10630	COG3304	Inner membrane component domain
GTK58_RS10635	COG0210	DNA helicase
GTK58_RS10645	COG1832	CoA-binding protein
GTK58_RS10660	COG1881	PFAM PEBP family protein
GTK58_RS10665	COG2207	Transcriptional regulator
GTK58_RS10680	COG0670	Belongs to the BI1 family
GTK58_RS10695	COG2200	EAL domain
GTK58_RS10700	COG2200	EAL domain
GTK58_RS10710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GTK58_RS10715	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS10720	COG4638	Rieske (2fe-2S)
GTK58_RS10725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GTK58_RS10730	COG0473	3-isopropylmalate dehydrogenase activity
GTK58_RS10735	COG0583	DNA-binding transcription factor activity
GTK58_RS10740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GTK58_RS10745	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS10750	COG1917	Cupin 2, conserved barrel domain protein
GTK58_RS10750	COG1396	sequence-specific DNA binding
GTK58_RS10755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GTK58_RS10760	COG0174	glutamine synthetase
GTK58_RS10765	COG0531	amino acid
GTK58_RS10780	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS10785	COG1733	regulation of RNA biosynthetic process
GTK58_RS10805	COG3729	General stress protein
GTK58_RS10815	COG2233	PERMEase
GTK58_RS10850	COG1309	transcriptional regulator
GTK58_RS10865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GTK58_RS10875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GTK58_RS10880	COG0672	)-iron permease
GTK58_RS10895	COG1702	phosphate starvation-inducible protein PhoH
GTK58_RS10910	COG1335	isochorismatase
GTK58_RS10920	COG0583	DNA-binding transcription factor activity
GTK58_RS10950	COG3381	protein complex oligomerization
GTK58_RS10985	COG5645	(Lipo)protein
GTK58_RS11000	COG1560	Kdo2-lipid A biosynthetic process
GTK58_RS11045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTK58_RS11065	COG2814	Major facilitator Superfamily
GTK58_RS11070	COG0583	DNA-binding transcription factor activity
GTK58_RS11075	COG1530	ribonuclease E activity
GTK58_RS11090	COG1399	metal-binding, possibly nucleic acid-binding protein
GTK58_RS11110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GTK58_RS11115	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS11125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GTK58_RS11130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GTK58_RS11135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GTK58_RS11145	COG0470	DNA polymerase III
GTK58_RS11150	COG0084	hydrolase, TatD family'
GTK58_RS11160	COG0537	adenosine 5'-monophosphoramidase activity
GTK58_RS11165	COG5633	Lipoprotein
GTK58_RS11190	COG1252	NADH dehydrogenase
GTK58_RS11195	COG3134	Outer membrane lipoprotein
GTK58_RS11205	COG1309	transcriptional regulator
GTK58_RS11215	COG1376	ErfK ybiS ycfS ynhG family protein
GTK58_RS11215	COG1388	LysM domain
GTK58_RS11220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GTK58_RS11225	COG4591	ABC-type transport system involved in lipoprotein release permease component
GTK58_RS11235	COG4591	ABC-type transport system involved in lipoprotein release permease component
GTK58_RS11245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GTK58_RS11255	COG0318	PFAM AMP-dependent synthetase and ligase
GTK58_RS11265	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GTK58_RS11270	COG1177	transmembrane transport
GTK58_RS11275	COG1176	ABC-type spermidine putrescine transport system, permease component I
GTK58_RS11290	COG2850	peptidyl-arginine hydroxylation
GTK58_RS11295	COG2205	protein histidine kinase activity
GTK58_RS11315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GTK58_RS11335	COG1187	pseudouridine synthase activity
GTK58_RS11340	COG0538	isocitrate dehydrogenase activity
GTK58_RS11345	COG0582	viral genome integration into host DNA
GTK58_RS11360	COG3316	Transposase and inactivated derivatives
GTK58_RS11385	COG1396	sequence-specific DNA binding
GTK58_RS11430	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GTK58_RS11435	COG3344	reverse transcriptase
GTK58_RS11455	COG1403	HNH endonuclease
GTK58_RS11480	COG3772	lysozyme
GTK58_RS11520	COG4626	Terminase
GTK58_RS11520	COG1802	Transcriptional regulator
GTK58_RS11535	COG0616	signal peptide processing
GTK58_RS11620	COG0538	isocitrate dehydrogenase activity
GTK58_RS11625	COG0640	Transcriptional regulator
GTK58_RS11640	COG3813	Protein conserved in bacteria
GTK58_RS11645	COG1063	alcohol dehydrogenase
GTK58_RS11650	COG3729	General stress protein
GTK58_RS11655	COG3685	Protein conserved in bacteria
GTK58_RS11660	COG3685	Protein conserved in bacteria
GTK58_RS11665	COG3546	catalase activity
GTK58_RS11670	COG1271	oxidase subunit
GTK58_RS11675	COG1294	oxidase, subunit
GTK58_RS11700	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GTK58_RS11705	COG0583	DNA-binding transcription factor activity
GTK58_RS11710	COG3706	GGDEF domain
GTK58_RS11715	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GTK58_RS11725	COG1560	Kdo2-lipid A biosynthetic process
GTK58_RS11735	COG3182	Iron-regulated membrane protein
GTK58_RS11755	COG2203	Gaf domain
GTK58_RS11755	COG2199	diguanylate cyclase activity
GTK58_RS11760	COG3042	response to heat
GTK58_RS11765	COG3189	MarR family transcriptional regulator
GTK58_RS11770	COG1683	Conserved Protein
GTK58_RS11775	COG0504	CTP synthase activity
GTK58_RS11780	COG2807	transmembrane transport
GTK58_RS11785	COG2207	Transcriptional regulator
GTK58_RS11795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GTK58_RS11800	COG0859	PFAM glycosyl transferase family 9
GTK58_RS11810	COG3344	reverse transcriptase
GTK58_RS11815	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GTK58_RS11820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GTK58_RS11825	COG0583	DNA-binding transcription factor activity
GTK58_RS11830	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS11850	COG0386	Belongs to the glutathione peroxidase family
GTK58_RS11865	COG2766	serine protein kinase
GTK58_RS11870	COG3713	MltA-interacting MipA family protein
GTK58_RS11885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GTK58_RS11895	COG3139	Protein of unknown function (DUF1315)
GTK58_RS11900	COG1403	HNH endonuclease
GTK58_RS11910	COG1063	alcohol dehydrogenase
GTK58_RS11915	COG2271	Major facilitator Superfamily
GTK58_RS11920	COG1063	alcohol dehydrogenase
GTK58_RS11925	COG0191	fructose-bisphosphate aldolase activity
GTK58_RS11930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTK58_RS11935	COG0667	Aldo Keto reductase
GTK58_RS11940	COG1349	DNA-binding transcription factor activity
GTK58_RS11945	COG2814	Major facilitator Superfamily
GTK58_RS11950	COG1335	isochorismatase
GTK58_RS11955	COG0252	asparaginase activity
GTK58_RS11960	COG0616	signal peptide processing
GTK58_RS11965	COG0778	Nitroreductase
GTK58_RS11980	COG0709	Synthesizes selenophosphate from selenide and ATP
GTK58_RS11985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GTK58_RS11995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GTK58_RS12000	COG0494	nUDIX hydrolase
GTK58_RS12005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GTK58_RS12010	COG2897	thiosulfate sulfurtransferase activity
GTK58_RS12015	COG4136	ATPase activity
GTK58_RS12020	COG4135	transport system, permease component
GTK58_RS12025	COG4134	Bacterial extracellular solute-binding protein
GTK58_RS12030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GTK58_RS12035	COG0398	Pfam SNARE associated Golgi protein
GTK58_RS12040	COG0398	Pfam SNARE associated Golgi protein
GTK58_RS12045	COG0708	Exodeoxyribonuclease III
GTK58_RS12055	COG3138	arginine N-succinyltransferase
GTK58_RS12065	COG3724	N-succinylarginine dihydrolase activity
GTK58_RS12075	COG3678	ATP-independent chaperone mediated protein folding
GTK58_RS12080	COG0322	excinuclease ABC activity
GTK58_RS12090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTK58_RS12095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS12100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS12105	COG1447	Phosphotransferase system cellobiose-specific component IIA
GTK58_RS12110	COG1917	Cupin 2, conserved barrel domain protein
GTK58_RS12110	COG2169	Transcriptional regulator
GTK58_RS12115	COG1486	melibiose metabolic process
GTK58_RS12125	COG0753	catalase activity
GTK58_RS12140	COG1988	membrane-bound metal-dependent
GTK58_RS12145	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS12150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTK58_RS12160	COG1607	acyl-coa hydrolase
GTK58_RS12185	COG3047	cAMP biosynthetic process
GTK58_RS12195	COG4774	siderophore transport
GTK58_RS12250	COG0135	phosphoribosylanthranilate isomerase activity
GTK58_RS12250	COG0134	indole-3-glycerol-phosphate synthase activity
GTK58_RS12255	COG0512	Glutamine amidotransferase of anthranilate synthase
GTK58_RS12255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GTK58_RS12260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GTK58_RS12270	COG0009	L-threonylcarbamoyladenylate synthase
GTK58_RS12280	COG0583	DNA-binding transcription factor activity
GTK58_RS12285	COG1187	pseudouridine synthase activity
GTK58_RS12290	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GTK58_RS12295	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS12305	COG0616	signal peptide processing
GTK58_RS12315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GTK58_RS12330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GTK58_RS12340	COG0671	phosphoesterase, PA-phosphatase related
GTK58_RS12345	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GTK58_RS12350	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GTK58_RS12360	COG0023	Translation Initiation Factor
GTK58_RS12370	COG1349	DNA-binding transcription factor activity
GTK58_RS12385	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GTK58_RS12385	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GTK58_RS12390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GTK58_RS12400	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GTK58_RS12415	COG4171	peptide transport system, permease
GTK58_RS12420	COG4168	peptide transport system, permease
GTK58_RS12430	COG0702	epimerase
GTK58_RS12445	COG1473	amidohydrolase
GTK58_RS12455	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GTK58_RS12460	COG1842	Phage shock protein A
GTK58_RS12470	COG1983	PspC domain protein
GTK58_RS12480	COG3106	COG3106 Predicted ATPase
GTK58_RS12490	COG0583	DNA-binding transcription factor activity
GTK58_RS12495	COG1486	melibiose metabolic process
GTK58_RS12500	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GTK58_RS12505	COG3180	Ammonia monooxygenase
GTK58_RS12510	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GTK58_RS12515	COG4948	Mandelate Racemase Muconate Lactonizing
GTK58_RS12520	COG2866	Carboxypeptidase
GTK58_RS12525	COG4166	transmembrane transport
GTK58_RS12555	COG0656	L-ascorbic acid biosynthetic process
GTK58_RS12575	COG0583	DNA-binding transcription factor activity
GTK58_RS12580	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS12585	COG1078	dGTPase activity
GTK58_RS12590	COG0693	protein deglycase activity
GTK58_RS12595	COG0582	viral genome integration into host DNA
GTK58_RS12695	COG0484	heat shock protein binding
GTK58_RS12705	COG3772	lysozyme
GTK58_RS12725	COG1783	phage Terminase large subunit
GTK58_RS12730	COG3567	Phage-associated protein, HI1409 family
GTK58_RS12800	COG0739	heme binding
GTK58_RS12800	COG1196	nuclear chromosome segregation
GTK58_RS12800	COG0741	lytic transglycosylase activity
GTK58_RS12895	COG3039	Transposase
GTK58_RS12920	COG2885	chlorophyll binding
GTK58_RS13020	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS13025	COG1309	transcriptional regulator
GTK58_RS13030	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS13050	COG0583	DNA-binding transcription factor activity
GTK58_RS13080	COG0436	Aminotransferase
GTK58_RS13095	COG2011	ABC-type metal ion transport system permease component
GTK58_RS13100	COG1448	Aminotransferase
GTK58_RS13110	COG1522	sequence-specific DNA binding
GTK58_RS13115	COG1113	amino acid transport
GTK58_RS13130	COG0673	inositol 2-dehydrogenase activity
GTK58_RS13135	COG1349	DNA-binding transcription factor activity
GTK58_RS13145	COG0513	Belongs to the DEAD box helicase family
GTK58_RS13155	COG0589	response to stress
GTK58_RS13165	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTK58_RS13170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GTK58_RS13170	COG1013	pyruvate-flavodoxin oxidoreductase activity
GTK58_RS13170	COG0674	pyruvate-flavodoxin oxidoreductase activity
GTK58_RS13170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTK58_RS13175	COG3042	response to heat
GTK58_RS13180	COG3187	Heat shock protein
GTK58_RS13185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GTK58_RS13190	COG0586	Pfam SNARE associated Golgi protein
GTK58_RS13195	COG2911	Protein conserved in bacteria
GTK58_RS13205	COG3784	Protein of unknown function (DUF1318)
GTK58_RS13210	COG2207	Transcriptional regulator
GTK58_RS13215	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS13235	COG2030	dehydratase
GTK58_RS13235	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS13240	COG3396	Phenylacetate-CoA oxygenase
GTK58_RS13245	COG3460	Phenylacetate-CoA oxygenase
GTK58_RS13250	COG3396	Phenylacetate-CoA oxygenase
GTK58_RS13255	COG2151	metal-sulfur cluster biosynthetic enzyme
GTK58_RS13260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GTK58_RS13265	COG1024	Enoyl-CoA hydratase
GTK58_RS13270	COG1024	Enoyl-CoA hydratase
GTK58_RS13275	COG1250	3-hydroxyacyl-CoA dehydrogenase
GTK58_RS13280	COG2050	protein possibly involved in aromatic compounds catabolism
GTK58_RS13285	COG0183	Belongs to the thiolase family
GTK58_RS13290	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GTK58_RS13295	COG3327	negative regulation of DNA-templated transcription, initiation
GTK58_RS13300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GTK58_RS13315	COG1643	Atp-dependent helicase
GTK58_RS13325	COG1538	Outer membrane efflux protein
GTK58_RS13345	COG0583	DNA-binding transcription factor activity
GTK58_RS13350	COG0667	Aldo Keto reductase
GTK58_RS13355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GTK58_RS13360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GTK58_RS13365	COG3138	arginine N-succinyltransferase
GTK58_RS13370	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS13375	COG3724	N-succinylarginine dihydrolase activity
GTK58_RS13380	COG2988	succinylglutamate desuccinylase activity
GTK58_RS13385	COG1113	amino acid transport
GTK58_RS13390	COG0477	Major facilitator Superfamily
GTK58_RS13395	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GTK58_RS13400	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS13405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GTK58_RS13410	COG0401	homolog of Blt101
GTK58_RS13415	COG5562	phage envelope protein
GTK58_RS13420	COG0425	Belongs to the sulfur carrier protein TusA family
GTK58_RS13425	COG2391	methyltransferase activity
GTK58_RS13450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GTK58_RS13455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTK58_RS13455	COG1263	PTS System
GTK58_RS13460	COG1609	Transcriptional regulator
GTK58_RS13465	COG5339	Protein conserved in bacteria
GTK58_RS13470	COG1482	cell wall glycoprotein biosynthetic process
GTK58_RS13475	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GTK58_RS13475	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GTK58_RS13480	COG0114	fumarate hydratase activity
GTK58_RS13490	COG2205	protein histidine kinase activity
GTK58_RS13500	COG0745	RESPONSE REGULATOR receiver
GTK58_RS13505	COG3136	membrane protein required for alginate biosynthesis
GTK58_RS13515	COG0531	amino acid
GTK58_RS13525	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GTK58_RS13530	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GTK58_RS13545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GTK58_RS13550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GTK58_RS13560	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GTK58_RS13565	COG1473	amidohydrolase
GTK58_RS13575	COG0583	DNA-binding transcription factor activity
GTK58_RS13580	COG2840	Smr protein MutS2
GTK58_RS13585	COG1414	Transcriptional regulator
GTK58_RS13595	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GTK58_RS13600	COG0183	Belongs to the thiolase family
GTK58_RS13610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GTK58_RS13615	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GTK58_RS13625	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GTK58_RS13625	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GTK58_RS13635	COG1053	succinate dehydrogenase
GTK58_RS13645	COG4565	transcriptional regulatory protein
GTK58_RS13650	COG3290	protein histidine kinase activity
GTK58_RS13675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GTK58_RS13685	COG0679	Auxin Efflux Carrier
GTK58_RS13715	COG0628	permease
GTK58_RS13735	COG3591	Belongs to the peptidase S1B family
GTK58_RS13745	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GTK58_RS13750	COG2814	Major facilitator Superfamily
GTK58_RS13755	COG0583	DNA-binding transcription factor activity
GTK58_RS13760	COG1940	carbohydrate kinase activity
GTK58_RS13765	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GTK58_RS13780	COG3302	dmso reductase anchor subunit
GTK58_RS13785	COG0437	4 iron, 4 sulfur cluster binding
GTK58_RS13790	COG0243	molybdopterin cofactor binding
GTK58_RS13805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTK58_RS13820	COG2271	Major facilitator Superfamily
GTK58_RS13825	COG0246	Mannitol dehydrogenase
GTK58_RS13830	COG0589	response to stress
GTK58_RS13835	COG1802	Transcriptional regulator
GTK58_RS13840	COG4221	oxidoreductase activity
GTK58_RS13855	COG2207	Transcriptional regulator
GTK58_RS13860	COG2135	peptidase activity
GTK58_RS13870	COG2197	response regulator
GTK58_RS13875	COG3039	Transposase
GTK58_RS13880	COG0071	Belongs to the small heat shock protein (HSP20) family
GTK58_RS13885	COG1546	Belongs to the CinA family
GTK58_RS13890	COG2200	EAL domain
GTK58_RS13905	COG3708	Transcriptional regulator
GTK58_RS13905	COG2207	Transcriptional regulator
GTK58_RS13910	COG2610	gluconate transmembrane transporter activity
GTK58_RS13915	COG3622	Belongs to the hyi family
GTK58_RS13920	COG0235	Class ii aldolase
GTK58_RS13925	COG3395	kinase activity
GTK58_RS13930	COG2084	Dehydrogenase
GTK58_RS13935	COG1349	DNA-binding transcription factor activity
GTK58_RS13950	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GTK58_RS13955	COG2223	nitrite transmembrane transporter activity
GTK58_RS13990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GTK58_RS13995	COG0683	leucine binding
GTK58_RS14000	COG0559	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS14010	COG1129	ABC transporter
GTK58_RS14015	COG0410	ABC transporter
GTK58_RS14025	COG2814	Major facilitator Superfamily
GTK58_RS14030	COG0697	spore germination
GTK58_RS14040	COG4977	sequence-specific DNA binding
GTK58_RS14045	COG1846	Transcriptional regulator
GTK58_RS14065	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS14070	COG2731	YhcH YjgK YiaL family protein
GTK58_RS14085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GTK58_RS14095	COG3395	kinase activity
GTK58_RS14100	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GTK58_RS14105	COG1349	DNA-binding transcription factor activity
GTK58_RS14110	COG0039	L-malate dehydrogenase activity
GTK58_RS14120	COG0583	DNA-binding transcription factor activity
GTK58_RS14125	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS14140	COG2199	diguanylate cyclase activity
GTK58_RS14205	COG0477	Major facilitator Superfamily
GTK58_RS14215	COG0477	Major facilitator Superfamily
GTK58_RS14225	COG2070	2-Nitropropane dioxygenase
GTK58_RS14230	COG2011	ABC-type metal ion transport system permease component
GTK58_RS14250	COG4628	conserved protein (DUF2132)
GTK58_RS14265	COG2207	Transcriptional regulator
GTK58_RS14295	COG2233	PERMEase
GTK58_RS14300	COG3195	allantoin biosynthetic process
GTK58_RS14300	COG3648	Uricase
GTK58_RS14305	COG2351	hydroxyisourate hydrolase activity
GTK58_RS14310	COG1396	sequence-specific DNA binding
GTK58_RS14315	COG3550	peptidyl-serine autophosphorylation
GTK58_RS14330	COG3188	usher protein
GTK58_RS14350	COG0024	Methionine aminopeptidase
GTK58_RS14365	COG5001	Diguanylate cyclase
GTK58_RS14365	COG3300	MHYT domain
GTK58_RS14370	COG2819	hydrolase of the alpha beta superfamily
GTK58_RS14380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS14380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS14385	COG2814	Major facilitator Superfamily
GTK58_RS14395	COG1263	PTS System
GTK58_RS14395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTK58_RS14400	COG2186	Transcriptional regulator
GTK58_RS14420	COG3835	regulator
GTK58_RS14425	COG1929	Belongs to the glycerate kinase type-1 family
GTK58_RS14470	COG0738	Major facilitator superfamily
GTK58_RS14475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTK58_RS14480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GTK58_RS14485	COG1349	DNA-binding transcription factor activity
GTK58_RS14500	COG1349	DNA-binding transcription factor activity
GTK58_RS14505	COG4977	sequence-specific DNA binding
GTK58_RS14525	COG4977	sequence-specific DNA binding
GTK58_RS14540	COG0667	Aldo Keto reductase
GTK58_RS14550	COG0667	Aldo Keto reductase
GTK58_RS14555	COG0667	Aldo Keto reductase
GTK58_RS14565	COG0456	acetyltransferase
GTK58_RS14565	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GTK58_RS14580	COG1840	ABC-type Fe3 transport system, periplasmic component
GTK58_RS14590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GTK58_RS14590	COG0426	domain, Protein
GTK58_RS14605	COG1652	LysM domain
GTK58_RS14635	COG1609	Transcriptional regulator
GTK58_RS14645	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS14660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GTK58_RS14670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GTK58_RS14675	COG0583	DNA-binding transcription factor activity
GTK58_RS14680	COG0583	DNA-binding transcription factor activity
GTK58_RS14695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTK58_RS14695	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GTK58_RS14695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTK58_RS14700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTK58_RS14710	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GTK58_RS14715	COG3037	sugar-specific permease SgaT UlaA
GTK58_RS14725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS14730	COG1609	Transcriptional regulator
GTK58_RS14740	COG2223	nitrite transmembrane transporter activity
GTK58_RS14770	COG0477	Major facilitator Superfamily
GTK58_RS14775	COG4529	Protein conserved in bacteria
GTK58_RS14780	COG1902	pentaerythritol trinitrate reductase activity
GTK58_RS14790	COG0583	DNA-binding transcription factor activity
GTK58_RS14795	COG2070	2-Nitropropane dioxygenase
GTK58_RS14805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GTK58_RS14880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GTK58_RS14915	COG1335	isochorismatase
GTK58_RS14925	COG0406	alpha-ribazole phosphatase activity
GTK58_RS14960	COG1953	Uracil, thiamine, allantoin
GTK58_RS14965	COG0402	S-adenosylhomocysteine deaminase activity
GTK58_RS14970	COG3706	GGDEF domain
GTK58_RS14985	COG0673	inositol 2-dehydrogenase activity
GTK58_RS14995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GTK58_RS15000	COG1116	anion transmembrane transporter activity
GTK58_RS15005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTK58_RS15010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GTK58_RS15015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GTK58_RS15020	COG0076	glutamate decarboxylase activity
GTK58_RS15035	COG2205	protein histidine kinase activity
GTK58_RS15040	COG0745	RESPONSE REGULATOR receiver
GTK58_RS15045	COG0596	Alpha beta hydrolase
GTK58_RS15085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GTK58_RS15085	COG0519	Catalyzes the synthesis of GMP from XMP
GTK58_RS15105	COG0583	DNA-binding transcription factor activity
GTK58_RS15115	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GTK58_RS15120	COG1285	pathogenesis
GTK58_RS15125	COG2814	Major facilitator Superfamily
GTK58_RS15130	COG1447	Phosphotransferase system cellobiose-specific component IIA
GTK58_RS15135	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS15160	COG3039	Transposase
GTK58_RS15170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS15175	COG0583	DNA-binding transcription factor activity
GTK58_RS15180	COG0243	molybdopterin cofactor binding
GTK58_RS15185	COG3781	membrane
GTK58_RS15205	COG1764	response to oxidative stress
GTK58_RS15210	COG3111	PFAM Bacterial OB fold (BOF) protein
GTK58_RS15220	COG2323	membrane
GTK58_RS15230	COG0366	Alpha amylase catalytic
GTK58_RS15240	COG3685	Protein conserved in bacteria
GTK58_RS15250	COG3729	General stress protein
GTK58_RS15255	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS15295	COG0488	(ABC) transporter
GTK58_RS15310	COG1064	alcohol dehydrogenase
GTK58_RS15315	COG0747	negative chemotaxis
GTK58_RS15335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GTK58_RS15345	COG2814	Major facilitator Superfamily
GTK58_RS15355	COG2326	polyphosphate kinase activity
GTK58_RS15370	COG2864	formate dehydrogenase
GTK58_RS15375	COG0437	4 iron, 4 sulfur cluster binding
GTK58_RS15400	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GTK58_RS15410	COG3485	protocatechuate 3,4-dioxygenase
GTK58_RS15415	COG4829	muconolactone delta-isomerase
GTK58_RS15420	COG4948	Mandelate Racemase Muconate Lactonizing
GTK58_RS15425	COG1414	Transcriptional regulator
GTK58_RS15445	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GTK58_RS15450	COG1140	nitrate reductase beta subunit
GTK58_RS15455	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GTK58_RS15460	COG2181	nitrate reductase activity
GTK58_RS15465	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GTK58_RS15470	COG1178	ABC-type Fe3 transport system permease component
GTK58_RS15475	COG1840	ABC-type Fe3 transport system, periplasmic component
GTK58_RS15480	COG3842	ATPase activity
GTK58_RS15485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GTK58_RS15500	COG2211	Major facilitator Superfamily
GTK58_RS15520	COG0625	glutathione transferase activity
GTK58_RS15530	COG1126	abc transporter atp-binding protein
GTK58_RS15535	COG0765	amino acid transport
GTK58_RS15550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GTK58_RS15560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GTK58_RS15590	COG4772	TonB-dependent receptor
GTK58_RS15595	COG1228	amidohydrolase
GTK58_RS15600	COG3691	Protein conserved in bacteria
GTK58_RS15610	COG2130	NADP-dependent
GTK58_RS15620	COG1247	-acetyltransferase
GTK58_RS15625	COG3238	Protein conserved in bacteria
GTK58_RS15635	COG0747	negative chemotaxis
GTK58_RS15640	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS15675	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS15680	COG1177	transmembrane transport
GTK58_RS15685	COG1176	ABC-type spermidine putrescine transport system, permease component I
GTK58_RS15690	COG3842	ATPase activity
GTK58_RS15695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GTK58_RS15700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTK58_RS15705	COG1271	oxidase subunit
GTK58_RS15710	COG1294	oxidase, subunit
GTK58_RS15730	COG0826	peptidase U32
GTK58_RS15740	COG1396	sequence-specific DNA binding
GTK58_RS15745	COG3135	benzoate transporter
GTK58_RS15750	COG2207	Transcriptional regulator
GTK58_RS15750	COG3708	Transcriptional regulator
GTK58_RS15765	COG0500	methyltransferase
GTK58_RS15770	COG1275	C4-dicarboxylate transporter malic acid transport protein
GTK58_RS15775	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GTK58_RS15780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTK58_RS15795	COG2272	Belongs to the type-B carboxylesterase lipase family
GTK58_RS15800	COG5383	Protein conserved in bacteria
GTK58_RS15805	COG3485	protocatechuate 3,4-dioxygenase
GTK58_RS15810	COG3485	protocatechuate 3,4-dioxygenase
GTK58_RS15815	COG0583	DNA-binding transcription factor activity
GTK58_RS15835	COG3038	cytochrome b561
GTK58_RS15850	COG1733	regulation of RNA biosynthetic process
GTK58_RS15855	COG2814	Major facilitator Superfamily
GTK58_RS15865	COG0673	inositol 2-dehydrogenase activity
GTK58_RS15875	COG2723	6-phospho-beta-galactosidase activity
GTK58_RS15910	COG4659	FMN binding
GTK58_RS15920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GTK58_RS15930	COG0625	glutathione transferase activity
GTK58_RS15935	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GTK58_RS15950	COG3895	Periplasmic Protein
GTK58_RS15960	COG3133	Outer membrane lipoprotein
GTK58_RS15965	COG3706	GGDEF domain
GTK58_RS15980	COG1566	PFAM secretion protein HlyD family protein
GTK58_RS15985	COG1289	transmembrane transporter activity
GTK58_RS15990	COG2032	superoxide dismutase activity
GTK58_RS15995	COG4989	oxidoreductase activity
GTK58_RS16000	COG3313	Fe-S protein
GTK58_RS16005	COG1309	transcriptional regulator
GTK58_RS16010	COG1902	pentaerythritol trinitrate reductase activity
GTK58_RS16015	COG0346	lactoylglutathione lyase activity
GTK58_RS16025	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GTK58_RS16030	COG0791	NLP P60 protein
GTK58_RS16040	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GTK58_RS16045	COG2814	Major facilitator Superfamily
GTK58_RS16060	COG0583	DNA-binding transcription factor activity
GTK58_RS16065	COG2814	Major facilitator Superfamily
GTK58_RS16070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GTK58_RS16075	COG0307	riboflavin synthase, alpha
GTK58_RS16125	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GTK58_RS16155	COG1349	DNA-binding transcription factor activity
GTK58_RS16160	COG0346	lactoylglutathione lyase activity
GTK58_RS16185	COG0444	Belongs to the ABC transporter superfamily
GTK58_RS16190	COG4608	Belongs to the ABC transporter superfamily
GTK58_RS16255	COG0583	DNA-binding transcription factor activity
GTK58_RS16265	COG0402	S-adenosylhomocysteine deaminase activity
GTK58_RS16290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTK58_RS16295	COG0277	FAD linked oxidase domain protein
GTK58_RS16320	COG0583	DNA-binding transcription factor activity
GTK58_RS16330	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GTK58_RS16340	COG1250	3-hydroxyacyl-CoA dehydrogenase
GTK58_RS16345	COG2610	gluconate transmembrane transporter activity
GTK58_RS16350	COG1028	Short-chain dehydrogenase reductase Sdr
GTK58_RS16405	COG3039	Transposase
GTK58_RS16425	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GTK58_RS16445	COG3088	subunit of a heme lyase
GTK58_RS16445	COG4235	cytochrome complex assembly
GTK58_RS16450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GTK58_RS16455	COG1138	Cytochrome C-type biogenesis protein
GTK58_RS16470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GTK58_RS16475	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GTK58_RS16480	COG4133	protoheme IX ABC transporter activity
GTK58_RS16510	COG1175	transmembrane transport
GTK58_RS16515	COG1840	ABC-type Fe3 transport system, periplasmic component
GTK58_RS16520	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GTK58_RS16525	COG3383	formate dehydrogenase (NAD+) activity
GTK58_RS16530	COG1473	amidohydrolase
GTK58_RS16545	COG2814	Major facilitator Superfamily
GTK58_RS16560	COG1126	abc transporter atp-binding protein
GTK58_RS16565	COG0765	amino acid transport
GTK58_RS16585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTK58_RS16590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTK58_RS16595	COG1120	ATPase activity
GTK58_RS16600	COG4774	siderophore transport
GTK58_RS16605	COG1116	anion transmembrane transporter activity
GTK58_RS16610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GTK58_RS16630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GTK58_RS16635	COG0583	DNA-binding transcription factor activity
GTK58_RS16655	COG2814	Major facilitator Superfamily
GTK58_RS16690	COG1414	Transcriptional regulator
GTK58_RS16715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GTK58_RS16720	COG2271	Major facilitator Superfamily
GTK58_RS16730	COG1309	transcriptional regulator
GTK58_RS16755	COG1376	ErfK ybiS ycfS ynhG family protein
GTK58_RS16770	COG0719	Fe-S assembly protein
GTK58_RS16775	COG0396	ATPase activity
GTK58_RS16780	COG0719	Fe-S assembly protein
GTK58_RS16785	COG0316	Belongs to the HesB IscA family
GTK58_RS16800	COG1309	transcriptional regulator
GTK58_RS16805	COG1304	FMN binding
GTK58_RS16830	COG0583	DNA-binding transcription factor activity
GTK58_RS16840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTK58_RS16845	COG1120	ATPase activity
GTK58_RS16870	COG2261	transglycosylase associated protein
GTK58_RS16875	COG2050	protein possibly involved in aromatic compounds catabolism
GTK58_RS16880	COG0277	FAD linked oxidase domain protein
GTK58_RS16880	COG0247	lactate metabolic process
GTK58_RS16885	COG0628	permease
GTK58_RS16895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GTK58_RS16895	COG0574	Belongs to the PEP-utilizing enzyme family
GTK58_RS16905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GTK58_RS16910	COG4256	Hemin uptake protein
GTK58_RS16920	COG0791	NLP P60 protein
GTK58_RS16930	COG0386	Belongs to the glutathione peroxidase family
GTK58_RS16950	COG0583	DNA-binding transcription factor activity
GTK58_RS16970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTK58_RS16970	COG0072	phenylalanine-tRNA ligase activity
GTK58_RS17010	COG3137	Salt-induced outer membrane protein
GTK58_RS17015	COG1105	Belongs to the carbohydrate kinase PfkB family
GTK58_RS17035	COG2350	Protein conserved in bacteria
GTK58_RS17040	COG2353	YceI-like domain
GTK58_RS17060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GTK58_RS17070	COG0444	Belongs to the ABC transporter superfamily
GTK58_RS17075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTK58_RS17080	COG0601	transmembrane transport
GTK58_RS17085	COG4166	transmembrane transport
GTK58_RS17090	COG2095	MarC family integral membrane protein
GTK58_RS17095	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS17095	COG1454	alcohol dehydrogenase
GTK58_RS17100	COG1435	thymidine kinase activity
GTK58_RS17105	COG2916	Histone family protein nucleoid-structuring protein H-NS
GTK58_RS17110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GTK58_RS17115	COG0745	RESPONSE REGULATOR receiver
GTK58_RS17120	COG1752	Esterase of the alpha-beta hydrolase superfamily
GTK58_RS17130	COG0788	formyltetrahydrofolate deformylase activity
GTK58_RS17165	COG1522	sequence-specific DNA binding
GTK58_RS17175	COG2181	nitrate reductase activity
GTK58_RS17180	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GTK58_RS17185	COG1140	nitrate reductase beta subunit
GTK58_RS17190	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GTK58_RS17195	COG2223	nitrite transmembrane transporter activity
GTK58_RS17200	COG3850	Histidine kinase
GTK58_RS17205	COG2197	response regulator
GTK58_RS17210	COG4932	domain protein
GTK58_RS17215	COG0243	molybdopterin cofactor binding
GTK58_RS17220	COG2146	nitrite reductase [NAD(P)H] activity
GTK58_RS17220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GTK58_RS17225	COG1116	anion transmembrane transporter activity
GTK58_RS17235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GTK58_RS17240	COG3707	response regulator
GTK58_RS17245	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GTK58_RS17255	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GTK58_RS17260	COG4572	Cation transport regulator
GTK58_RS17265	COG0387	Pfam Sodium calcium exchanger
GTK58_RS17275	COG2912	Transglutaminase-like superfamily
GTK58_RS17280	COG3094	Invasion gene expression up-regulator, SirB
GTK58_RS17285	COG2890	protein-(glutamine-N5) methyltransferase activity
GTK58_RS17310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GTK58_RS17315	COG0659	secondary active sulfate transmembrane transporter activity
GTK58_RS17335	COG0012	GTP binding
GTK58_RS17470	COG3501	Rhs element vgr protein
GTK58_RS17475	COG2885	chlorophyll binding
GTK58_RS17500	COG3122	Protein conserved in bacteria
GTK58_RS17515	COG0583	DNA-binding transcription factor activity
GTK58_RS17545	COG0583	DNA-binding transcription factor activity
GTK58_RS17550	COG0410	ABC transporter
GTK58_RS17565	COG0559	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS17575	COG1882	Formate acetyltransferase
GTK58_RS17590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GTK58_RS17595	COG0583	DNA-binding transcription factor activity
GTK58_RS17630	COG2308	Evidence 4 Homologs of previously reported genes of
GTK58_RS17645	COG4774	siderophore transport
GTK58_RS17655	COG1619	proteins homologs of microcin C7 resistance protein MccF
GTK58_RS17675	COG2719	SpoVR family
GTK58_RS17705	COG0179	Fumarylacetoacetate (FAA) hydrolase
GTK58_RS17720	COG2894	cell division
GTK58_RS17730	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GTK58_RS17735	COG0318	PFAM AMP-dependent synthetase and ligase
GTK58_RS17740	COG3065	identical protein binding
GTK58_RS17750	COG1199	ATP-dependent helicase activity
GTK58_RS17755	COG0251	oxidation-reduction process
GTK58_RS17775	COG1760	l-serine dehydratase
GTK58_RS17780	COG2200	EAL domain
GTK58_RS17785	COG1253	flavin adenine dinucleotide binding
GTK58_RS17790	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS17790	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTK58_RS17795	COG3715	PTS system
GTK58_RS17800	COG3716	PTS system mannose fructose sorbose family IID component
GTK58_RS17815	COG2226	methyltransferase
GTK58_RS17820	COG0768	penicillin binding
GTK58_RS17825	COG1278	Cold shock
GTK58_RS17850	COG1414	Transcriptional regulator
GTK58_RS17855	COG2814	Major facilitator Superfamily
GTK58_RS17875	COG1956	GAF domain-containing protein
GTK58_RS17880	COG2995	paraquat-inducible protein a
GTK58_RS17885	COG3008	intermembrane lipid transfer
GTK58_RS17910	COG2990	Protein conserved in bacteria
GTK58_RS17925	COG1276	copper resistance
GTK58_RS17930	COG2372	response to copper ion
GTK58_RS17940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GTK58_RS17945	COG1770	oligopeptidase
GTK58_RS17950	COG2979	Protein of unknown function (DUF533)
GTK58_RS17955	COG3141	response to X-ray
GTK58_RS17965	COG0800	Aldolase
GTK58_RS17970	COG0129	dihydroxy-acid dehydratase activity
GTK58_RS17975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GTK58_RS17980	COG1737	Transcriptional regulator
GTK58_RS17990	COG1560	Kdo2-lipid A biosynthetic process
GTK58_RS17995	COG0739	heme binding
GTK58_RS18000	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GTK58_RS18010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GTK58_RS18035	COG0494	nUDIX hydrolase
GTK58_RS18045	COG1335	isochorismatase
GTK58_RS18050	COG1801	Protein of unknown function DUF72
GTK58_RS18055	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GTK58_RS18075	COG3102	Protein conserved in bacteria
GTK58_RS18085	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GTK58_RS18110	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS18120	COG1879	ABC-type sugar transport system periplasmic component
GTK58_RS18125	COG1528	Iron-storage protein
GTK58_RS18130	COG2211	Major facilitator Superfamily
GTK58_RS18140	COG0477	Major facilitator Superfamily
GTK58_RS18155	COG1528	Iron-storage protein
GTK58_RS18165	COG0814	amino acid
GTK58_RS18170	COG3012	SEC-C Motif Domain Protein
GTK58_RS18170	COG3318	Belongs to the UPF0149 family
GTK58_RS18215	COG3772	lysozyme
GTK58_RS18245	COG0741	lytic transglycosylase activity
GTK58_RS18400	COG0305	Participates in initiation and elongation during chromosome replication
GTK58_RS18475	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GTK58_RS18485	COG2197	response regulator
GTK58_RS18495	COG2197	response regulator
GTK58_RS18520	COG0366	Alpha amylase catalytic
GTK58_RS18550	COG2354	Protein conserved in bacteria
GTK58_RS18555	COG0697	spore germination
GTK58_RS18560	COG3727	T/G mismatch-specific endonuclease activity
GTK58_RS18565	COG0270	DNA (cytosine-5-)-methyltransferase activity
GTK58_RS18570	COG1418	mRNA catabolic process
GTK58_RS18580	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTK58_RS18625	COG0025	NhaP-type Na H and K H
GTK58_RS18630	COG1309	transcriptional regulator
GTK58_RS18635	COG0604	alcohol dehydrogenase
GTK58_RS18655	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GTK58_RS18665	COG0534	Mate efflux family protein
GTK58_RS18675	COG0582	viral genome integration into host DNA
GTK58_RS18680	COG1169	isochorismate synthase
GTK58_RS18685	COG2814	Major facilitator Superfamily
GTK58_RS18690	COG1132	(ABC) transporter
GTK58_RS18705	COG3433	isochorismatase activity
GTK58_RS18705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GTK58_RS18705	COG2226	methyltransferase
GTK58_RS18725	COG1021	2,3-dihydroxybenzoate-AMP ligase
GTK58_RS18730	COG4771	TonB-dependent receptor
GTK58_RS18790	COG3039	Transposase
GTK58_RS18805	COG3504	Conjugal transfer protein
GTK58_RS18850	COG2003	Belongs to the UPF0758 family
GTK58_RS18900	COG3706	GGDEF domain
GTK58_RS18925	COG3615	Tellurite resistance protein tehB
GTK58_RS18930	COG3300	MHYT domain
GTK58_RS18930	COG5001	Diguanylate cyclase
GTK58_RS18940	COG0477	Major facilitator Superfamily
GTK58_RS18945	COG0095	Lipoate-protein ligase
GTK58_RS18950	COG0583	DNA-binding transcription factor activity
GTK58_RS18955	COG1942	4-Oxalocrotonate Tautomerase
GTK58_RS18965	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GTK58_RS18985	COG1289	transmembrane transporter activity
GTK58_RS18995	COG3344	reverse transcriptase
GTK58_RS19005	COG2925	Exonuclease
GTK58_RS19010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GTK58_RS19015	COG0640	Transcriptional regulator
GTK58_RS19020	COG0531	amino acid
GTK58_RS19030	COG0583	DNA-binding transcription factor activity
GTK58_RS19035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTK58_RS19065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GTK58_RS19140	COG1088	dTDP-glucose 4,6-dehydratase activity
GTK58_RS19175	COG1088	dTDP-glucose 4,6-dehydratase activity
GTK58_RS19185	COG2244	polysaccharide biosynthetic process
GTK58_RS19200	COG0463	Glycosyl transferase, family 2
GTK58_RS19250	COG1253	flavin adenine dinucleotide binding
GTK58_RS19255	COG2982	Protein involved in outer membrane biogenesis
GTK58_RS19270	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GTK58_RS19275	COG0443	Heat shock 70 kDa protein
GTK58_RS19280	COG5002	protein histidine kinase activity
GTK58_RS19300	COG1301	dicarboxylic acid transport
GTK58_RS19325	COG2205	protein histidine kinase activity
GTK58_RS19330	COG0745	RESPONSE REGULATOR receiver
GTK58_RS19345	COG4608	Belongs to the ABC transporter superfamily
GTK58_RS19350	COG0444	Belongs to the ABC transporter superfamily
GTK58_RS19360	COG0601	transmembrane transport
GTK58_RS19365	COG0747	negative chemotaxis
GTK58_RS19370	COG4948	Mandelate Racemase Muconate Lactonizing
GTK58_RS19375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTK58_RS19385	COG1070	Carbohydrate kinase
GTK58_RS19420	COG1830	Aldolase
GTK58_RS19425	COG0351	phosphomethylpyrimidine kinase
GTK58_RS19440	COG0583	DNA-binding transcription factor activity
GTK58_RS19450	COG2252	PERMEase
GTK58_RS19455	COG0583	DNA-binding transcription factor activity
GTK58_RS19460	COG5455	response to cobalt ion
GTK58_RS19480	COG4807	Protein conserved in bacteria
GTK58_RS19490	COG3275	phosphorelay sensor kinase activity
GTK58_RS19500	COG1174	glycine betaine transport
GTK58_RS19505	COG1125	glycine betaine transport
GTK58_RS19510	COG1174	glycine betaine transport
GTK58_RS19515	COG1732	Glycine betaine
GTK58_RS19520	COG1472	Belongs to the glycosyl hydrolase 3 family
GTK58_RS19525	COG0277	FAD linked oxidase domain protein
GTK58_RS19535	COG1686	Belongs to the peptidase S11 family
GTK58_RS19545	COG0586	Pfam SNARE associated Golgi protein
GTK58_RS19550	COG1538	Outer membrane efflux protein
GTK58_RS19555	COG2723	6-phospho-beta-galactosidase activity
GTK58_RS19570	COG3659	wide pore channel activity
GTK58_RS19575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GTK58_RS19585	COG1346	cytolysis
GTK58_RS19595	COG2949	membrane
GTK58_RS19605	COG1129	ABC transporter
GTK58_RS19620	COG2311	Membrane
GTK58_RS19635	COG4771	TonB-dependent receptor
GTK58_RS19645	COG0833	amino acid
GTK58_RS19650	COG0583	DNA-binding transcription factor activity
GTK58_RS19655	COG2855	membrane
GTK58_RS19665	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GTK58_RS19665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTK58_RS19665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTK58_RS19670	COG1105	Belongs to the carbohydrate kinase PfkB family
GTK58_RS19675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS19675	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS19700	COG1312	Catalyzes the dehydration of D-mannonate
GTK58_RS19705	COG0246	Mannitol dehydrogenase
GTK58_RS19710	COG0523	cobalamin synthesis protein
GTK58_RS19715	COG0671	phosphoesterase, PA-phosphatase related
GTK58_RS19720	COG0791	NLP P60 protein
GTK58_RS19725	COG2200	EAL domain
GTK58_RS19730	COG4166	transmembrane transport
GTK58_RS19735	COG4174	ABC transporter (Permease)
GTK58_RS19740	COG4239	(ABC) transporter, permease
GTK58_RS19745	COG4172	Belongs to the ABC transporter superfamily
GTK58_RS19755	COG2814	Major facilitator Superfamily
GTK58_RS19760	COG1187	pseudouridine synthase activity
GTK58_RS19765	COG1061	Type III restriction enzyme res subunit
GTK58_RS19785	COG0494	nUDIX hydrolase
GTK58_RS19790	COG1349	DNA-binding transcription factor activity
GTK58_RS19815	COG0628	permease
GTK58_RS19830	COG0659	secondary active sulfate transmembrane transporter activity
GTK58_RS19835	COG2239	Acts as a magnesium transporter
GTK58_RS19840	COG4615	Cyclic peptide transporter
GTK58_RS19845	COG3145	DNA-N1-methyladenine dioxygenase activity
GTK58_RS19850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GTK58_RS19850	COG2169	Transcriptional regulator
GTK58_RS19865	COG2198	Histidine kinase
GTK58_RS19865	COG0642	Histidine kinase
GTK58_RS19875	COG0784	Response regulator, receiver
GTK58_RS19875	COG2205	protein histidine kinase activity
GTK58_RS19900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GTK58_RS19905	COG0584	glycerophosphoryl diester phosphodiesterase
GTK58_RS19910	COG2271	Major facilitator Superfamily
GTK58_RS19915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GTK58_RS19925	COG0247	lactate metabolic process
GTK58_RS19935	COG2271	Major facilitator Superfamily
GTK58_RS19945	COG1414	Transcriptional regulator
GTK58_RS19960	COG5464	transposase or invertase
GTK58_RS19970	COG0318	PFAM AMP-dependent synthetase and ligase
GTK58_RS19995	COG1169	isochorismate synthase
GTK58_RS20000	COG2153	protein acetylation
GTK58_RS20015	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTK58_RS20020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GTK58_RS20030	COG0839	Belongs to the complex I subunit 6 family
GTK58_RS20045	COG1034	ATP synthesis coupled electron transport
GTK58_RS20055	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GTK58_RS20075	COG0583	DNA-binding transcription factor activity
GTK58_RS20080	COG0436	Aminotransferase
GTK58_RS20090	COG0471	metal ion transport
GTK58_RS20090	COG0490	domain, Protein
GTK58_RS20095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTK58_RS20110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GTK58_RS20115	COG0857	belongs to the CobB CobQ family
GTK58_RS20115	COG0280	phosphate acetyltransferase
GTK58_RS20120	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GTK58_RS20125	COG0622	Phosphoesterase
GTK58_RS20130	COG0625	glutathione transferase activity
GTK58_RS20135	COG0625	glutathione transferase activity
GTK58_RS20140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GTK58_RS20145	COG1090	epimerase
GTK58_RS20155	COG4598	ABC transporter
GTK58_RS20160	COG4160	amino acid transport
GTK58_RS20165	COG4215	(ABC) transporter
GTK58_RS20175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTK58_RS20180	COG0163	prenyltransferase activity
GTK58_RS20185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GTK58_RS20190	COG1286	toxin biosynthetic process
GTK58_RS20195	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GTK58_RS20200	COG0285	dihydrofolate synthase activity
GTK58_RS20210	COG0586	Pfam SNARE associated Golgi protein
GTK58_RS20220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GTK58_RS20240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GTK58_RS20255	COG3101	peptidyl-lysine hydroxylation
GTK58_RS20260	COG0730	response to heat
GTK58_RS20275	COG2890	protein-(glutamine-N5) methyltransferase activity
GTK58_RS20285	COG2062	phosphohistidine phosphatase, SixA
GTK58_RS20300	COG3691	Protein conserved in bacteria
GTK58_RS20310	COG2853	Lipoprotein
GTK58_RS20315	COG2116	formate transmembrane transporter activity
GTK58_RS20335	COG0583	DNA-binding transcription factor activity
GTK58_RS20340	COG0590	tRNA wobble adenosine to inosine editing
GTK58_RS20345	COG2807	transmembrane transport
GTK58_RS20355	COG0436	Aminotransferase
GTK58_RS20360	COG3275	phosphorelay sensor kinase activity
GTK58_RS20365	COG3279	Response regulator of the LytR AlgR family
GTK58_RS20380	COG3961	Belongs to the TPP enzyme family
GTK58_RS20385	COG0667	Aldo Keto reductase
GTK58_RS20400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GTK58_RS20405	COG2200	EAL domain
GTK58_RS20405	COG2199	diguanylate cyclase activity
GTK58_RS20420	COG3415	Transposase
GTK58_RS20425	COG3415	Transposase
GTK58_RS20455	COG0583	DNA-binding transcription factor activity
GTK58_RS20460	COG0385	Bile acid
GTK58_RS20465	COG3530	Putative quorum-sensing-regulated virulence factor
GTK58_RS20485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GTK58_RS20500	COG2190	(PTS) system
GTK58_RS20520	COG4319	ketosteroid isomerase
GTK58_RS20530	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GTK58_RS20535	COG4208	sulfate ABC transporter
GTK58_RS20540	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GTK58_RS20545	COG4150	thiosulfate binding
GTK58_RS20555	COG2837	iron assimilation
GTK58_RS20575	COG0860	N-Acetylmuramoyl-L-alanine amidase
GTK58_RS20595	COG4816	utilization protein
GTK58_RS20625	COG4820	ethanolamine utilization protein (EutJ)
GTK58_RS20660	COG4917	ethanolamine utilization protein
GTK58_RS20665	COG4810	utilization protein
GTK58_RS20675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GTK58_RS20680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GTK58_RS20685	COG5342	invasion associated locus B
GTK58_RS20695	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GTK58_RS20695	COG0493	'glutamate synthase
GTK58_RS20700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTK58_RS20710	COG1393	Belongs to the ArsC family
GTK58_RS20725	COG0400	carboxylic ester hydrolase activity
GTK58_RS20730	COG1444	tRNA N-acetyltransferase activity
GTK58_RS20735	COG2321	neutral zinc metallopeptidase
GTK58_RS20745	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GTK58_RS20755	COG2716	regulation of RNA biosynthetic process
GTK58_RS20760	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GTK58_RS20765	COG0628	permease
GTK58_RS20770	COG4783	chaperone-mediated protein folding
GTK58_RS20775	COG1393	Belongs to the ArsC family
GTK58_RS20790	COG2233	PERMEase
GTK58_RS20800	COG2723	6-phospho-beta-galactosidase activity
GTK58_RS20815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GTK58_RS20825	COG0248	Ppx GppA phosphatase
GTK58_RS20830	COG2200	EAL domain
GTK58_RS20850	COG0641	radical SAM
GTK58_RS20865	COG3179	chitinase
GTK58_RS20900	COG3039	Transposase
GTK58_RS20920	COG3344	reverse transcriptase
GTK58_RS21000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GTK58_RS21045	COG0517	IMP dehydrogenase activity
GTK58_RS21045	COG0516	GMP reductase activity
GTK58_RS21055	COG1645	bacterial-type flagellum-dependent swarming motility
GTK58_RS21075	COG2976	Protein conserved in bacteria
GTK58_RS21105	COG4953	penicillin-binding protein 1C
GTK58_RS21110	COG2373	Large extracellular alpha-helical protein
GTK58_RS21115	COG2897	thiosulfate sulfurtransferase activity
GTK58_RS21135	COG2975	iron-sulfur cluster assembly
GTK58_RS21140	COG0633	Ferredoxin
GTK58_RS21160	COG0822	iron-sulfur transferase activity
GTK58_RS21190	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GTK58_RS21195	COG3683	transport system, periplasmic component
GTK58_RS21200	COG3711	transcriptional antiterminator
GTK58_RS21205	COG2814	Major facilitator Superfamily
GTK58_RS21210	COG2017	converts alpha-aldose to the beta-anomer
GTK58_RS21215	COG2814	Major facilitator Superfamily
GTK58_RS21215	COG0477	Major facilitator Superfamily
GTK58_RS21220	COG0457	Tetratricopeptide repeat
GTK58_RS21225	COG1940	carbohydrate kinase activity
GTK58_RS21230	COG2259	Doxx family
GTK58_RS21240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GTK58_RS21240	COG1017	nitric oxide dioxygenase activity
GTK58_RS21245	COG0347	Belongs to the P(II) protein family
GTK58_RS21250	COG2204	response regulator
GTK58_RS21255	COG3170	Tfp pilus assembly protein FimV
GTK58_RS21260	COG2205	protein histidine kinase activity
GTK58_RS21265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GTK58_RS21265	COG0047	phosphoribosylformylglycinamidine synthase activity
GTK58_RS21275	COG0590	tRNA wobble adenosine to inosine editing
GTK58_RS21280	COG0560	Phosphoserine phosphatase
GTK58_RS21285	COG1737	Transcriptional regulator
GTK58_RS21290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GTK58_RS21300	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GTK58_RS21320	COG0681	Belongs to the peptidase S26 family
GTK58_RS21330	COG3086	response to oxidative stress
GTK58_RS21335	COG3026	antisigma factor binding
GTK58_RS21340	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GTK58_RS21355	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GTK58_RS21365	COG0513	Belongs to the DEAD box helicase family
GTK58_RS21380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTK58_RS21385	COG3118	belongs to the thioredoxin family
GTK58_RS21400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GTK58_RS21405	COG5544	Lipoprotein
GTK58_RS21410	COG0477	Major facilitator Superfamily
GTK58_RS21440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GTK58_RS21450	COG2011	ABC-type metal ion transport system permease component
GTK58_RS21455	COG1464	Belongs to the NlpA lipoprotein family
GTK58_RS21465	COG1720	tRNA m6t6A37 methyltransferase activity
GTK58_RS21475	COG0791	NLP P60 protein
GTK58_RS21480	COG3015	lipoprotein NlpE involved in copper resistance
GTK58_RS21485	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GTK58_RS21490	COG4681	YaeQ
GTK58_RS21500	COG4568	rho-dependent transcription termination
GTK58_RS21510	COG0346	lactoylglutathione lyase activity
GTK58_RS21555	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GTK58_RS21565	COG0750	zinc metalloprotease
GTK58_RS21570	COG0575	Belongs to the CDS family
GTK58_RS21580	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GTK58_RS21605	COG0024	Methionine aminopeptidase
GTK58_RS21610	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GTK58_RS21625	COG3835	regulator
GTK58_RS21630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GTK58_RS21650	COG2860	membrane
GTK58_RS21670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTK58_RS21675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GTK58_RS21680	COG1120	ATPase activity
GTK58_RS21690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GTK58_RS21780	COG1643	Atp-dependent helicase
GTK58_RS21785	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GTK58_RS21795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GTK58_RS21805	COG0617	tRNA 3'-terminal CCA addition
GTK58_RS21810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GTK58_RS21830	COG0726	polysaccharide deacetylase
GTK58_RS21835	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS21840	COG0842	Transport permease protein
GTK58_RS21845	COG1131	(ABC) transporter
GTK58_RS21850	COG0288	reversible hydration of carbon dioxide
GTK58_RS21860	COG4993	Dehydrogenase
GTK58_RS21865	COG2132	Multicopper oxidase
GTK58_RS21920	COG3064	Membrane
GTK58_RS21935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTK58_RS21940	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTK58_RS21945	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GTK58_RS21950	COG2186	Transcriptional regulator
GTK58_RS21955	COG1113	amino acid transport
GTK58_RS21960	COG2211	Major facilitator Superfamily
GTK58_RS21965	COG3940	Belongs to the glycosyl hydrolase 43 family
GTK58_RS21970	COG3725	Membrane protein required for beta-lactamase induction
GTK58_RS21975	COG3023	N-Acetylmuramoyl-L-alanine amidase
GTK58_RS21985	COG4969	Belongs to the N-Me-Phe pilin family
GTK58_RS21990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GTK58_RS21995	COG1459	type II secretion system
GTK58_RS22005	COG0237	dephospho-CoA kinase activity
GTK58_RS22020	COG0494	nUDIX hydrolase
GTK58_RS22040	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GTK58_RS22045	COG0849	cell division
GTK58_RS22055	COG1181	Belongs to the D-alanine--D-alanine ligase family
GTK58_RS22070	COG0772	Belongs to the SEDS family
GTK58_RS22085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GTK58_RS22090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GTK58_RS22095	COG0768	penicillin binding
GTK58_RS22115	COG1609	Transcriptional regulator
GTK58_RS22125	COG0028	Belongs to the TPP enzyme family
GTK58_RS22170	COG0738	Major facilitator superfamily
GTK58_RS22180	COG0583	DNA-binding transcription factor activity
GTK58_RS22185	COG2271	Major facilitator Superfamily
GTK58_RS22190	COG2814	Major facilitator Superfamily
GTK58_RS22205	COG4143	(ABC) transporter
GTK58_RS22210	COG1178	ABC-type Fe3 transport system permease component
GTK58_RS22220	COG0586	Pfam SNARE associated Golgi protein
GTK58_RS22240	COG0235	Class ii aldolase
GTK58_RS22245	COG0417	DNA replication proofreading
GTK58_RS22255	COG0564	pseudouridine synthase activity
GTK58_RS22265	COG3493	citrate carrier protein
GTK58_RS22280	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GTK58_RS22285	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GTK58_RS22295	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GTK58_RS22340	COG0505	Belongs to the CarA family
GTK58_RS22405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GTK58_RS22430	COG1047	Peptidyl-prolyl cis-trans
GTK58_RS22445	COG0196	riboflavin kinase activity
GTK58_RS22460	COG0583	DNA-binding transcription factor activity
GTK58_RS22485	COG4735	regulation of single-species biofilm formation
GTK58_RS22490	COG1584	GPR1 FUN34 yaaH family protein
GTK58_RS22495	COG0477	Major facilitator Superfamily
GTK58_RS22500	COG0521	Mo-molybdopterin cofactor biosynthetic process
GTK58_RS22510	COG1115	amino acid carrier protein
GTK58_RS22525	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GTK58_RS22535	COG0460	homoserine dehydrogenase
GTK58_RS22535	COG0527	aspartate kinase activity
GTK58_RS22545	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GTK58_RS22555	COG0745	RESPONSE REGULATOR receiver
GTK58_RS22560	COG4452	Inner membrane protein CreD
GTK58_RS22565	COG2205	protein histidine kinase activity
GTK58_RS22570	COG0745	RESPONSE REGULATOR receiver
GTK58_RS22575	COG3045	CreA protein
GTK58_RS22580	COG2207	Transcriptional regulator
GTK58_RS22580	COG3708	Transcriptional regulator
GTK58_RS22600	COG0741	lytic transglycosylase activity
GTK58_RS22605	COG0488	(ABC) transporter
GTK58_RS22615	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GTK58_RS22620	COG0560	Phosphoserine phosphatase
GTK58_RS22655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GTK58_RS22660	COG0084	hydrolase, TatD family'
GTK58_RS22665	COG4667	esterase of the alpha-beta hydrolase superfamily
GTK58_RS22675	COG2823	Periplasmic or secreted lipoprotein
GTK58_RS22685	COG1011	Hydrolase
GTK58_RS22690	COG0456	acetyltransferase
GTK58_RS22695	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GTK58_RS22725	COG3706	GGDEF domain
GTK58_RS22730	COG4114	ferric iron reductase
GTK58_RS22735	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS22735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS22740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GTK58_RS22745	COG2197	response regulator
GTK58_RS22750	COG2197	response regulator
GTK58_RS22765	COG2966	Psort location CytoplasmicMembrane, score
GTK58_RS22780	COG1484	DNA-dependent DNA replication
GTK58_RS22795	COG5464	transposase or invertase
GTK58_RS22805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GTK58_RS22810	COG3716	PTS system mannose fructose sorbose family IID component
GTK58_RS22815	COG3715	PTS system
GTK58_RS22830	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GTK58_RS22830	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GTK58_RS22840	COG1063	alcohol dehydrogenase
GTK58_RS22845	COG1802	Transcriptional regulator
GTK58_RS22850	COG2271	Major facilitator Superfamily
GTK58_RS22855	COG0456	acetyltransferase
GTK58_RS22855	COG1214	PFAM Peptidase M22, glycoprotease
GTK58_RS22865	COG1737	Transcriptional regulator
GTK58_RS22870	COG0800	Aldolase
GTK58_RS22875	COG3734	2-keto-3-deoxy-galactonokinase
GTK58_RS22890	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GTK58_RS22915	COG1846	Transcriptional regulator
GTK58_RS22920	COG0179	Fumarylacetoacetate (FAA) hydrolase
GTK58_RS22930	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS22935	COG3384	dioxygenase
GTK58_RS22945	COG3971	2-oxopent-4-enoate hydratase activity
GTK58_RS22965	COG2368	4-hydroxyphenylacetate
GTK58_RS22970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GTK58_RS22985	COG3039	Transposase
GTK58_RS22995	COG1966	Carbon starvation protein
GTK58_RS23000	COG2879	small protein
GTK58_RS23005	COG0523	cobalamin synthesis protein
GTK58_RS23015	COG1012	belongs to the aldehyde dehydrogenase family
GTK58_RS23020	COG5464	transposase or invertase
GTK58_RS23025	COG1917	Cupin 2, conserved barrel domain protein
GTK58_RS23025	COG2207	Transcriptional regulator
GTK58_RS23035	COG2733	membrane
GTK58_RS23040	COG2814	Major facilitator Superfamily
GTK58_RS23050	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GTK58_RS23055	COG1924	4 iron, 4 sulfur cluster binding
GTK58_RS23070	COG1566	PFAM secretion protein HlyD family protein
GTK58_RS23080	COG5457	Domain of unknown function (DUF1127)
GTK58_RS23085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTK58_RS23095	COG0583	DNA-binding transcription factor activity
GTK58_RS23100	COG2249	NAD(P)H dehydrogenase (quinone) activity
GTK58_RS23110	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS23115	COG1129	ABC transporter
GTK58_RS23120	COG1879	ABC-type sugar transport system periplasmic component
GTK58_RS23130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTK58_RS23135	COG0842	Transport permease protein
GTK58_RS23135	COG1129	ABC transporter
GTK58_RS23140	COG0842	Transport permease protein
GTK58_RS23170	COG2850	peptidyl-arginine hydroxylation
GTK58_RS23185	COG5002	protein histidine kinase activity
GTK58_RS23190	COG0745	RESPONSE REGULATOR receiver
GTK58_RS23195	COG1538	Outer membrane efflux protein
GTK58_RS23200	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTK58_RS23205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTK58_RS23210	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTK58_RS23220	COG3040	lipid binding
GTK58_RS23225	COG0789	Transcriptional regulator
GTK58_RS23235	COG0300	oxidoreductase activity
GTK58_RS23250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GTK58_RS23270	COG3272	Protein of unknown function (DUF1722)
GTK58_RS23275	COG4580	involved in the transport of maltose and maltodextrins
GTK58_RS23285	COG2211	Major facilitator Superfamily
GTK58_RS23290	COG3507	Belongs to the glycosyl hydrolase 43 family
GTK58_RS23395	COG3039	Transposase
GTK58_RS23405	COG0582	viral genome integration into host DNA
GTK58_RS23415	COG0288	reversible hydration of carbon dioxide
GTK58_RS23420	COG0659	secondary active sulfate transmembrane transporter activity
GTK58_RS23425	COG1064	alcohol dehydrogenase
GTK58_RS23435	COG0395	ABC-type sugar transport system, permease component
GTK58_RS23440	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GTK58_RS23445	COG3842	ATPase activity
GTK58_RS23450	COG1653	transport
GTK58_RS23460	COG1082	Xylose isomerase domain protein TIM barrel
GTK58_RS23470	COG3962	Belongs to the TPP enzyme family
GTK58_RS23475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTK58_RS23480	COG0837	glucose binding
GTK58_RS23480	COG1737	Transcriptional regulator
GTK58_RS23485	COG3718	enzyme involved in inositol metabolism
GTK58_RS23500	COG0433	COG0433 Predicted ATPase
GTK58_RS23505	COG0795	lipopolysaccharide-transporting ATPase activity
GTK58_RS23510	COG0795	lipopolysaccharide-transporting ATPase activity
GTK58_RS23520	COG2927	DNA polymerase III (CHI subunit)
GTK58_RS23525	COG0525	valine-tRNA ligase activity
GTK58_RS23540	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GTK58_RS23550	COG2188	Transcriptional regulator
GTK58_RS23555	COG1288	antiporter activity
GTK58_RS23560	COG1228	amidohydrolase
GTK58_RS23565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTK58_RS23570	COG2222	sugar isomerase
GTK58_RS23575	COG2731	YhcH YjgK YiaL family protein
GTK58_RS23615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTK58_RS23615	COG1263	PTS System
GTK58_RS23620	COG0366	Alpha amylase catalytic
GTK58_RS23625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTK58_RS23630	COG1486	melibiose metabolic process
GTK58_RS23650	COG0602	queuosine metabolic process
GTK58_RS23655	COG2026	Addiction module toxin, RelE StbE family
GTK58_RS23660	COG3077	Addiction module antitoxin, RelB DinJ family
GTK58_RS23665	COG3711	transcriptional antiterminator
GTK58_RS23665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTK58_RS23670	COG2706	6-phosphogluconolactonase activity
GTK58_RS23685	COG3964	amidohydrolase
GTK58_RS23715	COG3783	Cytochrome b(562)
GTK58_RS23720	COG0312	modulator of DNA gyrase
GTK58_RS23740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GTK58_RS23750	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS23755	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS23760	COG1129	ABC transporter
GTK58_RS23765	COG1879	ABC-type sugar transport system periplasmic component
GTK58_RS23770	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GTK58_RS23785	COG2105	PFAM AIG2 family protein
GTK58_RS23790	COG2911	Protein conserved in bacteria
GTK58_RS23795	COG0729	surface antigen
GTK58_RS23805	COG1253	flavin adenine dinucleotide binding
GTK58_RS23820	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GTK58_RS23835	COG1733	regulation of RNA biosynthetic process
GTK58_RS23840	COG0702	epimerase
GTK58_RS23850	COG0697	spore germination
GTK58_RS23860	COG1113	amino acid transport
GTK58_RS23865	COG0545	Peptidyl-prolyl cis-trans isomerase
GTK58_RS23870	COG3061	Opacity-associated protein A
GTK58_RS23885	COG2965	DNA replication, synthesis of RNA primer
GTK58_RS23925	COG3414	Phosphotransferase system galactitol-specific IIB component
GTK58_RS23945	COG1073	alpha beta
GTK58_RS23950	COG3650	response to hydrogen peroxide
GTK58_RS23960	COG1960	acyl-CoA dehydrogenase activity
GTK58_RS23965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTK58_RS23970	COG0557	exoribonuclease II activity
GTK58_RS23985	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GTK58_RS23995	COG0330	HflC and HflK could
GTK58_RS24000	COG0330	HflC and HflK could
GTK58_RS24005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GTK58_RS24025	COG0860	N-Acetylmuramoyl-L-alanine amidase
GTK58_RS24030	COG0802	atpase or kinase
GTK58_RS24035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GTK58_RS24035	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GTK58_RS24040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GTK58_RS24060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTK58_RS24080	COG3264	Mechanosensitive ion channel
GTK58_RS24080	COG1511	domain protein
GTK58_RS24085	COG0531	amino acid
GTK58_RS24095	COG1053	succinate dehydrogenase
GTK58_RS24100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GTK58_RS24120	COG2076	Multidrug Resistance protein
GTK58_RS24125	COG5510	response to toxic substance
GTK58_RS24140	COG1509	lysine 2,3-aminomutase activity
GTK58_RS24155	COG3121	Chaperone
GTK58_RS24210	COG0531	amino acid
GTK58_RS24215	COG3030	protein affecting phage T7 exclusion by the F plasmid
GTK58_RS24220	COG1027	Aspartate ammonia-lyase
GTK58_RS24225	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GTK58_RS24240	COG1309	transcriptional regulator
GTK58_RS24275	COG0457	Tetratricopeptide repeat
GTK58_RS24280	COG0726	polysaccharide deacetylase
GTK58_RS24280	COG1649	PFAM Uncharacterised BCR, COG1649
GTK58_RS24285	COG1215	transferase activity, transferring glycosyl groups
GTK58_RS24300	COG0861	Integral membrane protein TerC family
GTK58_RS24335	COG1486	melibiose metabolic process
GTK58_RS24340	COG2169	Transcriptional regulator
GTK58_RS24350	COG2824	Alkylphosphonate utilization operon protein PhnA
GTK58_RS24355	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GTK58_RS24360	COG2188	Transcriptional regulator
GTK58_RS24365	COG3624	Phosphonate C-P lyase system protein PhnG
GTK58_RS24370	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GTK58_RS24375	COG3626	phosphonate metabolism
GTK58_RS24380	COG3627	carbon phosphorus lyase activity
GTK58_RS24385	COG4107	phosphonate C-P lyase system protein PhnK
GTK58_RS24390	COG4778	phosphonate C-P lyase system protein PhnL
GTK58_RS24395	COG3454	Phosphonate metabolism
GTK58_RS24405	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GTK58_RS24415	COG4191	Histidine kinase
GTK58_RS24415	COG0784	Response regulator, receiver
GTK58_RS24420	COG1129	ABC transporter
GTK58_RS24425	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS24430	COG1879	ABC-type sugar transport system periplasmic component
GTK58_RS24460	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GTK58_RS24465	COG1301	dicarboxylic acid transport
GTK58_RS24475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GTK58_RS24480	COG3162	membrane
GTK58_RS24510	COG3539	Fimbrial protein
GTK58_RS24515	COG1346	cytolysis
GTK58_RS24520	COG1380	Effector of murein hydrolase LrgA
GTK58_RS24525	COG0583	DNA-binding transcription factor activity
GTK58_RS24530	COG0025	NhaP-type Na H and K H
GTK58_RS24535	COG2252	PERMEase
GTK58_RS24540	COG0625	glutathione transferase activity
GTK58_RS24545	COG0789	Transcriptional regulator
GTK58_RS24555	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GTK58_RS24585	COG1234	tRNA 3'-trailer cleavage
GTK58_RS24590	COG1609	Transcriptional regulator
GTK58_RS24595	COG0483	inositol monophosphate 1-phosphatase activity
GTK58_RS24605	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTK58_RS24625	COG4771	TonB-dependent receptor
GTK58_RS24630	COG0741	lytic transglycosylase activity
GTK58_RS24640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GTK58_RS24645	COG2315	Protein conserved in bacteria
GTK58_RS24650	COG0432	Pfam Uncharacterised protein family UPF0047
GTK58_RS24665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GTK58_RS24670	COG0305	Participates in initiation and elongation during chromosome replication
GTK58_RS24685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GTK58_RS24695	COG0735	belongs to the Fur family
GTK58_RS24700	COG3237	CsbD-like
GTK58_RS24705	COG0534	Mate efflux family protein
GTK58_RS24715	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GTK58_RS24785	COG0251	oxidation-reduction process
GTK58_RS24795	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GTK58_RS24805	COG0527	aspartate kinase activity
GTK58_RS24860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GTK58_RS24890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GTK58_RS24900	COG0456	acetyltransferase
GTK58_RS24930	COG0151	Belongs to the GarS family
GTK58_RS24940	COG4191	Histidine kinase
GTK58_RS24945	COG3678	ATP-independent chaperone mediated protein folding
GTK58_RS24955	COG0776	regulation of translation
GTK58_RS24960	COG3068	Protein conserved in bacteria
GTK58_RS24980	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GTK58_RS24995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GTK58_RS25000	COG2104	thiamine diphosphate biosynthetic process
GTK58_RS25015	COG3706	GGDEF domain
GTK58_RS25025	COG1447	Phosphotransferase system cellobiose-specific component IIA
GTK58_RS25030	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GTK58_RS25065	COG0250	Participates in transcription elongation, termination and antitermination
GTK58_RS25070	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GTK58_RS25110	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GTK58_RS25140	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GTK58_RS25150	COG1739	Uncharacterized protein family UPF0029
GTK58_RS25190	COG0805	protein transport
GTK58_RS25200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GTK58_RS25210	COG3165	ubiquinone biosynthetic process from chorismate
GTK58_RS25220	COG1322	Protein conserved in bacteria
GTK58_RS25240	COG0583	DNA-binding transcription factor activity
GTK58_RS25250	COG0561	phosphatase activity
GTK58_RS25255	COG2267	carboxylic ester hydrolase activity
GTK58_RS25260	COG1280	lysine exporter protein (LysE YggA)
GTK58_RS25270	COG1280	lysine exporter protein (LysE YggA)
GTK58_RS25285	COG2050	protein possibly involved in aromatic compounds catabolism
GTK58_RS25295	COG0598	Magnesium transport protein CorA
GTK58_RS25300	COG0210	DNA helicase
GTK58_RS25305	COG1011	Hydrolase
GTK58_RS25325	COG5567	small periplasmic lipoprotein
GTK58_RS25335	COG3072	Adenylate cyclase
GTK58_RS25350	COG2959	enzyme of heme biosynthesis
GTK58_RS25355	COG3071	HemY protein
GTK58_RS25380	COG1113	amino acid transport
GTK58_RS25400	COG2244	polysaccharide biosynthetic process
GTK58_RS25405	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GTK58_RS25410	COG0456	acetyltransferase
GTK58_RS25415	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GTK58_RS25420	COG1088	dTDP-glucose 4,6-dehydratase activity
GTK58_RS25425	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GTK58_RS25430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GTK58_RS25440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GTK58_RS25445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GTK58_RS25450	COG3118	belongs to the thioredoxin family
GTK58_RS25475	COG1811	Na channel or pump
GTK58_RS25485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTK58_RS25490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTK58_RS25500	COG0583	DNA-binding transcription factor activity
GTK58_RS25505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GTK58_RS25515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GTK58_RS25520	COG3978	acetolactate synthase activity
GTK58_RS25540	COG3085	chromosome segregation
GTK58_RS25615	COG0583	DNA-binding transcription factor activity
GTK58_RS25630	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GTK58_RS25645	COG3443	Belongs to the bacterial solute-binding protein 9 family
GTK58_RS25650	COG2207	Transcriptional regulator
GTK58_RS25660	COG0371	Dehydrogenase
GTK58_RS25665	COG0697	spore germination
GTK58_RS25675	COG0583	DNA-binding transcription factor activity
GTK58_RS25685	COG0737	Belongs to the 5'-nucleotidase family
GTK58_RS25695	COG0527	aspartate kinase activity
GTK58_RS25695	COG0460	homoserine dehydrogenase
GTK58_RS25700	COG0626	cystathionine gamma-synthase activity
GTK58_RS25715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GTK58_RS25720	COG1609	Transcriptional regulator
GTK58_RS25725	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GTK58_RS25740	COG1575	Belongs to the MenA family. Type 1 subfamily
GTK58_RS25760	COG3678	ATP-independent chaperone mediated protein folding
GTK58_RS25765	COG0745	RESPONSE REGULATOR receiver
GTK58_RS25770	COG2205	protein histidine kinase activity
GTK58_RS25775	COG2258	MOSC domain
GTK58_RS25780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GTK58_RS25815	COG1879	ABC-type sugar transport system periplasmic component
GTK58_RS25820	COG1129	ABC transporter
GTK58_RS25825	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS25835	COG1454	alcohol dehydrogenase
GTK58_RS25845	COG2211	Major facilitator Superfamily
GTK58_RS25905	COG0205	6-phosphofructokinase activity
GTK58_RS25925	COG0437	4 iron, 4 sulfur cluster binding
GTK58_RS25930	COG2864	formate dehydrogenase
GTK58_RS25945	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GTK58_RS25955	COG0456	acetyltransferase
GTK58_RS25970	COG1011	Hydrolase
GTK58_RS25980	COG0174	glutamine synthetase
GTK58_RS25985	COG3852	Histidine kinase
GTK58_RS26000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GTK58_RS26020	COG0204	Acyl-transferase
GTK58_RS26030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GTK58_RS26035	COG3084	Protein conserved in bacteria
GTK58_RS26045	COG1763	Mo-molybdopterin cofactor biosynthetic process
GTK58_RS26070	COG2186	Transcriptional regulator
GTK58_RS26075	COG0477	Major facilitator Superfamily
GTK58_RS26080	COG1609	Transcriptional regulator
GTK58_RS26085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTK58_RS26090	COG1879	ABC-type sugar transport system periplasmic component
GTK58_RS26095	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTK58_RS26130	COG1522	sequence-specific DNA binding
GTK58_RS26135	COG0716	FMN binding
GTK58_RS26150	COG3312	ion transport
GTK58_RS26200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GTK58_RS26205	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GTK58_RS26210	COG0573	inorganic phosphate transmembrane transporter activity
GTK58_RS26215	COG0581	inorganic phosphate transmembrane transporter activity
GTK58_RS26220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GTK58_RS26225	COG0704	Plays a role in the regulation of phosphate uptake
GTK58_RS26235	COG2382	esterase
GTK58_RS26240	COG0363	glucosamine-6-phosphate deaminase activity
GTK58_RS26245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTK58_RS26250	COG2252	PERMEase
GTK58_RS26255	COG0431	NADPH-dependent FMN reductase
GTK58_RS26260	COG2091	lysine biosynthetic process via aminoadipic acid
GTK58_RS26290	COG0759	Could be involved in insertion of integral membrane proteins into the membrane