locus-tag	class	description
CY657_RS00025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CY657_RS00030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CY657_RS00095	COG1196	nuclear chromosome segregation
CY657_RS00180	COG5484	DNA packaging
CY657_RS00180	COG3728	DNA packaging
CY657_RS00235	COG0484	heat shock protein binding
CY657_RS00240	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CY657_RS00295	COG1484	DNA-dependent DNA replication
CY657_RS00335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY657_RS00370	COG4171	peptide transport system, permease
CY657_RS00385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CY657_RS00395	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CY657_RS00400	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS00400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS00415	COG1349	DNA-binding transcription factor activity
CY657_RS00425	COG0023	Translation Initiation Factor
CY657_RS00435	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CY657_RS00440	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CY657_RS00445	COG0671	phosphoesterase, PA-phosphatase related
CY657_RS00455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CY657_RS00485	COG0616	signal peptide processing
CY657_RS00495	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS00500	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CY657_RS00510	COG0583	DNA-binding transcription factor activity
CY657_RS00520	COG0009	L-threonylcarbamoyladenylate synthase
CY657_RS00530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CY657_RS00535	COG0512	Glutamine amidotransferase of anthranilate synthase
CY657_RS00535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CY657_RS00540	COG0135	phosphoribosylanthranilate isomerase activity
CY657_RS00540	COG0134	indole-3-glycerol-phosphate synthase activity
CY657_RS00575	COG4774	siderophore transport
CY657_RS00585	COG3047	cAMP biosynthetic process
CY657_RS00590	COG0727	PFAM Uncharacterised protein family (UPF0153)
CY657_RS00620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS00625	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS00630	COG1988	membrane-bound metal-dependent
CY657_RS00635	COG1823	symporter activity
CY657_RS00645	COG0753	catalase activity
CY657_RS00655	COG1486	melibiose metabolic process
CY657_RS00660	COG1917	Cupin 2, conserved barrel domain protein
CY657_RS00660	COG2169	Transcriptional regulator
CY657_RS00665	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS00670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS00675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS00680	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CY657_RS00690	COG0322	excinuclease ABC activity
CY657_RS00695	COG3678	ATP-independent chaperone mediated protein folding
CY657_RS00705	COG3724	N-succinylarginine dihydrolase activity
CY657_RS00715	COG3138	arginine N-succinyltransferase
CY657_RS00725	COG0708	Exodeoxyribonuclease III
CY657_RS00730	COG0398	Pfam SNARE associated Golgi protein
CY657_RS00735	COG0398	Pfam SNARE associated Golgi protein
CY657_RS00740	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS00745	COG4134	Bacterial extracellular solute-binding protein
CY657_RS00750	COG4135	transport system, permease component
CY657_RS00755	COG4136	ATPase activity
CY657_RS00760	COG2897	thiosulfate sulfurtransferase activity
CY657_RS00765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CY657_RS00770	COG0494	nUDIX hydrolase
CY657_RS00775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CY657_RS00780	COG0604	alcohol dehydrogenase
CY657_RS00780	COG3321	synthase
CY657_RS00780	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS00785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CY657_RS00790	COG0709	Synthesizes selenophosphate from selenide and ATP
CY657_RS00805	COG0778	Nitroreductase
CY657_RS00810	COG0616	signal peptide processing
CY657_RS00815	COG0252	asparaginase activity
CY657_RS00820	COG1335	isochorismatase
CY657_RS00835	COG3139	Protein of unknown function (DUF1315)
CY657_RS00855	COG0656	L-ascorbic acid biosynthetic process
CY657_RS00860	COG3713	MltA-interacting MipA family protein
CY657_RS00865	COG2766	serine protein kinase
CY657_RS00880	COG0386	Belongs to the glutathione peroxidase family
CY657_RS00900	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS00905	COG0583	DNA-binding transcription factor activity
CY657_RS00910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CY657_RS00915	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CY657_RS00925	COG0859	PFAM glycosyl transferase family 9
CY657_RS00930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CY657_RS00940	COG2207	Transcriptional regulator
CY657_RS00945	COG2807	transmembrane transport
CY657_RS00950	COG0504	CTP synthase activity
CY657_RS00955	COG1683	Conserved Protein
CY657_RS00960	COG3189	MarR family transcriptional regulator
CY657_RS00965	COG3042	response to heat
CY657_RS00970	COG2199	diguanylate cyclase activity
CY657_RS00970	COG2203	Gaf domain
CY657_RS00990	COG3182	Iron-regulated membrane protein
CY657_RS01000	COG1560	Kdo2-lipid A biosynthetic process
CY657_RS01015	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CY657_RS01020	COG3706	GGDEF domain
CY657_RS01025	COG0583	DNA-binding transcription factor activity
CY657_RS01030	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CY657_RS01055	COG1294	oxidase, subunit
CY657_RS01060	COG1271	oxidase subunit
CY657_RS01070	COG3685	Protein conserved in bacteria
CY657_RS01075	COG3685	Protein conserved in bacteria
CY657_RS01080	COG3729	General stress protein
CY657_RS01085	COG1063	alcohol dehydrogenase
CY657_RS01090	COG3813	Protein conserved in bacteria
CY657_RS01110	COG0640	Transcriptional regulator
CY657_RS01115	COG0538	isocitrate dehydrogenase activity
CY657_RS01125	COG5001	Diguanylate cyclase
CY657_RS01125	COG3300	MHYT domain
CY657_RS01130	COG3706	GGDEF domain
CY657_RS01145	COG0582	viral genome integration into host DNA
CY657_RS01150	COG0538	isocitrate dehydrogenase activity
CY657_RS01155	COG1187	pseudouridine synthase activity
CY657_RS01175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CY657_RS01195	COG2205	protein histidine kinase activity
CY657_RS01200	COG2850	peptidyl-arginine hydroxylation
CY657_RS01210	COG1943	Transposase
CY657_RS01235	COG1177	transmembrane transport
CY657_RS01250	COG0318	PFAM AMP-dependent synthetase and ligase
CY657_RS01255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CY657_RS01260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CY657_RS01265	COG0698	ribose 5-phosphate isomerase
CY657_RS01280	COG3395	kinase activity
CY657_RS01295	COG2390	Transcriptional regulator
CY657_RS01305	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CY657_RS01315	COG4591	ABC-type transport system involved in lipoprotein release permease component
CY657_RS01325	COG4591	ABC-type transport system involved in lipoprotein release permease component
CY657_RS01335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CY657_RS01340	COG1376	ErfK ybiS ycfS ynhG family protein
CY657_RS01340	COG1388	LysM domain
CY657_RS01350	COG1309	transcriptional regulator
CY657_RS01360	COG3134	Outer membrane lipoprotein
CY657_RS01365	COG1252	NADH dehydrogenase
CY657_RS01390	COG5633	Lipoprotein
CY657_RS01395	COG0537	adenosine 5'-monophosphoramidase activity
CY657_RS01405	COG0084	hydrolase, TatD family'
CY657_RS01410	COG0470	DNA polymerase III
CY657_RS01420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CY657_RS01425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CY657_RS01430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CY657_RS01445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CY657_RS01465	COG1399	metal-binding, possibly nucleic acid-binding protein
CY657_RS01485	COG1530	ribonuclease E activity
CY657_RS01490	COG0583	DNA-binding transcription factor activity
CY657_RS01495	COG2814	Major facilitator Superfamily
CY657_RS01515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY657_RS01565	COG1560	Kdo2-lipid A biosynthetic process
CY657_RS01585	COG5645	(Lipo)protein
CY657_RS01625	COG3381	protein complex oligomerization
CY657_RS01665	COG1309	transcriptional regulator
CY657_RS01670	COG0583	DNA-binding transcription factor activity
CY657_RS01680	COG1335	isochorismatase
CY657_RS01690	COG1702	phosphate starvation-inducible protein PhoH
CY657_RS01710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY657_RS01720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CY657_RS01740	COG1309	transcriptional regulator
CY657_RS01775	COG2233	PERMEase
CY657_RS01790	COG3729	General stress protein
CY657_RS01815	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS01830	COG0531	amino acid
CY657_RS01840	COG0174	glutamine synthetase
CY657_RS01845	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CY657_RS01850	COG1917	Cupin 2, conserved barrel domain protein
CY657_RS01850	COG1396	sequence-specific DNA binding
CY657_RS01855	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS01860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY657_RS01870	COG0473	3-isopropylmalate dehydrogenase activity
CY657_RS01875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CY657_RS01880	COG4638	Rieske (2fe-2S)
CY657_RS01885	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS01890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS01900	COG2200	EAL domain
CY657_RS01905	COG2200	EAL domain
CY657_RS01920	COG0670	Belongs to the BI1 family
CY657_RS01935	COG2207	Transcriptional regulator
CY657_RS01940	COG1881	PFAM PEBP family protein
CY657_RS01955	COG1832	CoA-binding protein
CY657_RS01965	COG0210	DNA helicase
CY657_RS01970	COG3304	Inner membrane component domain
CY657_RS01975	COG1289	transmembrane transporter activity
CY657_RS01980	COG3070	regulator of competence-specific genes
CY657_RS02005	COG1067	ATP-dependent peptidase activity
CY657_RS02015	COG3130	regulation of translation
CY657_RS02025	COG3009	Protein conserved in bacteria
CY657_RS02030	COG3008	intermembrane lipid transfer
CY657_RS02030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CY657_RS02035	COG2995	paraquat-inducible protein a
CY657_RS02040	COG0488	(ABC) transporter
CY657_RS02050	COG0633	Ferredoxin
CY657_RS02050	COG3217	Mosc domain protein beta barrel domain protein
CY657_RS02065	COG0431	NADPH-dependent FMN reductase
CY657_RS02070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY657_RS02075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS02080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS02090	COG0308	aminopeptidase N
CY657_RS02105	COG1473	amidohydrolase
CY657_RS02115	COG0814	amino acid
CY657_RS02125	COG1522	sequence-specific DNA binding
CY657_RS02135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CY657_RS02140	COG1448	Aminotransferase
CY657_RS02145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY657_RS02150	COG3108	Peptidase M15
CY657_RS02160	COG2989	Protein conserved in bacteria
CY657_RS02170	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CY657_RS02180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CY657_RS02185	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CY657_RS02190	COG3173	Aminoglycoside phosphotransferase
CY657_RS02205	COG3214	Protein conserved in bacteria
CY657_RS02220	COG2333	competence protein COMEC
CY657_RS02220	COG0658	competence protein
CY657_RS02230	COG0539	negative regulation of cytoplasmic translation
CY657_RS02250	COG2323	membrane
CY657_RS02255	COG1944	ATP diphosphatase activity
CY657_RS02260	COG2116	formate transmembrane transporter activity
CY657_RS02265	COG1882	Formate acetyltransferase
CY657_RS02270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CY657_RS02275	COG0477	Major facilitator Superfamily
CY657_RS02285	COG3302	dmso reductase anchor subunit
CY657_RS02290	COG0437	4 iron, 4 sulfur cluster binding
CY657_RS02295	COG0243	molybdopterin cofactor binding
CY657_RS02305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CY657_RS02315	COG1178	ABC-type Fe3 transport system permease component
CY657_RS02315	COG1674	ftsk spoiiie
CY657_RS02325	COG0492	ferredoxin-NADP+ reductase activity
CY657_RS02330	COG4988	ABC transporter
CY657_RS02335	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CY657_RS02350	COG0542	response to heat
CY657_RS02360	COG1278	Cold shock
CY657_RS02375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS02380	COG3593	DNA synthesis involved in DNA repair
CY657_RS02390	COG2431	L-lysine efflux transmembrane transporter activity
CY657_RS02400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS02415	COG0028	Belongs to the TPP enzyme family
CY657_RS02420	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CY657_RS02425	COG0702	epimerase
CY657_RS02430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY657_RS02435	COG3023	N-Acetylmuramoyl-L-alanine amidase
CY657_RS02440	COG5001	Diguanylate cyclase
CY657_RS02440	COG4251	negative regulation of phosphorylation
CY657_RS02440	COG3706	GGDEF domain
CY657_RS02440	COG2203	Gaf domain
CY657_RS02455	COG1126	abc transporter atp-binding protein
CY657_RS02460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS02465	COG4215	(ABC) transporter
CY657_RS02470	COG4160	amino acid transport
CY657_RS02475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS02480	COG5002	protein histidine kinase activity
CY657_RS02485	COG0745	RESPONSE REGULATOR receiver
CY657_RS02500	COG1177	transmembrane transport
CY657_RS02505	COG1176	ABC-type spermidine putrescine transport system, permease component I
CY657_RS02510	COG3842	ATPase activity
CY657_RS02515	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CY657_RS02530	COG0778	Nitroreductase
CY657_RS02555	COG3226	Transcriptional regulator
CY657_RS02560	COG0738	Major facilitator superfamily
CY657_RS02565	COG0561	phosphatase activity
CY657_RS02570	COG2814	Major facilitator Superfamily
CY657_RS02580	COG0671	phosphoesterase, PA-phosphatase related
CY657_RS02585	COG1349	DNA-binding transcription factor activity
CY657_RS02590	COG1686	Belongs to the peptidase S11 family
CY657_RS02595	COG0625	glutathione transferase activity
CY657_RS02600	COG2133	pyrroloquinoline quinone binding
CY657_RS02610	COG2223	nitrite transmembrane transporter activity
CY657_RS02635	COG0747	negative chemotaxis
CY657_RS02650	COG0303	'Molybdopterin
CY657_RS02655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CY657_RS02660	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CY657_RS02665	COG1882	Formate acetyltransferase
CY657_RS02670	COG0561	phosphatase activity
CY657_RS02680	COG1609	Transcriptional regulator
CY657_RS02685	COG2271	Major facilitator Superfamily
CY657_RS02700	COG0488	(ABC) transporter
CY657_RS02705	COG2365	Tyrosine phosphatase family
CY657_RS02710	COG1376	ErfK ybiS ycfS ynhG family protein
CY657_RS02715	COG2188	Transcriptional regulator
CY657_RS02720	COG2723	6-phospho-beta-galactosidase activity
CY657_RS02725	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CY657_RS02740	COG2194	sulfuric ester hydrolase activity
CY657_RS02745	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CY657_RS02760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS02765	COG0765	amino acid transport
CY657_RS02770	COG1126	abc transporter atp-binding protein
CY657_RS02775	COG0668	transmembrane transport
CY657_RS02785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CY657_RS02795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CY657_RS02805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CY657_RS02810	COG1199	ATP-dependent helicase activity
CY657_RS02815	COG0513	Belongs to the DEAD box helicase family
CY657_RS02820	COG3958	Transketolase
CY657_RS02825	COG3959	Transketolase, thiamine diphosphate binding domain
CY657_RS02830	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS02835	COG2271	Major facilitator Superfamily
CY657_RS02840	COG0583	DNA-binding transcription factor activity
CY657_RS02845	COG1309	transcriptional regulator
CY657_RS02850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS02855	COG1131	(ABC) transporter
CY657_RS02860	COG0842	Transport permease protein
CY657_RS02865	COG0842	Transport permease protein
CY657_RS02880	COG3568	Endonuclease Exonuclease Phosphatase
CY657_RS02885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY657_RS02890	COG0392	lysyltransferase activity
CY657_RS02905	COG0670	Belongs to the BI1 family
CY657_RS02910	COG0314	molybdopterin synthase activity
CY657_RS02915	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CY657_RS02925	COG0521	Mo-molybdopterin cofactor biosynthetic process
CY657_RS02950	COG0745	RESPONSE REGULATOR receiver
CY657_RS02955	COG0642	Histidine kinase
CY657_RS02990	COG2226	methyltransferase
CY657_RS03010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY657_RS03015	COG1881	PFAM PEBP family protein
CY657_RS03055	COG4677	pectinesterase activity
CY657_RS03070	COG0589	response to stress
CY657_RS03075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS03105	COG0789	Transcriptional regulator
CY657_RS03110	COG2200	EAL domain
CY657_RS03135	COG0561	phosphatase activity
CY657_RS03145	COG4149	molybdate abc transporter
CY657_RS03150	COG0725	ABC transporter, periplasmic molybdate-binding protein
CY657_RS03160	COG3585	molybdate ion transport
CY657_RS03160	COG2005	Transcriptional regulator
CY657_RS03165	COG1119	ATPase activity
CY657_RS03175	COG1085	galactose-1-phosphate uridylyltransferase
CY657_RS03185	COG2017	converts alpha-aldose to the beta-anomer
CY657_RS03195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CY657_RS03210	COG3201	nicotinamide mononucleotide transporter
CY657_RS03215	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CY657_RS03260	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CY657_RS03265	COG2885	chlorophyll binding
CY657_RS03275	COG3064	Membrane
CY657_RS03280	COG0848	biopolymer transport protein
CY657_RS03285	COG0811	peptide transport
CY657_RS03290	COG0824	Thioesterase
CY657_RS03295	COG3790	cyd operon protein YbgE
CY657_RS03300	COG4890	Cyd operon protein YbgT
CY657_RS03305	COG1294	oxidase, subunit
CY657_RS03310	COG1271	oxidase subunit
CY657_RS03320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CY657_RS03330	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY657_RS03335	COG0567	Dehydrogenase, E1 component
CY657_RS03340	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CY657_RS03345	COG1053	succinate dehydrogenase
CY657_RS03350	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CY657_RS03355	COG2009	succinate dehydrogenase
CY657_RS03400	COG1984	allophanate hydrolase subunit 2
CY657_RS03405	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CY657_RS03420	COG0415	Belongs to the DNA photolyase family
CY657_RS03450	COG2205	protein histidine kinase activity
CY657_RS03455	COG0745	RESPONSE REGULATOR receiver
CY657_RS03465	COG0033	Phosphoglucomutase
CY657_RS03475	COG0596	Alpha beta hydrolase
CY657_RS03490	COG0735	belongs to the Fur family
CY657_RS03535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CY657_RS03540	COG1846	Transcriptional regulator
CY657_RS03540	COG1940	carbohydrate kinase activity
CY657_RS03545	COG0647	UMP catabolic process
CY657_RS03550	COG0367	asparagine synthase
CY657_RS03595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CY657_RS03605	COG1702	phosphate starvation-inducible protein PhoH
CY657_RS03630	COG0765	amino acid transport
CY657_RS03635	COG0765	amino acid transport
CY657_RS03640	COG1126	abc transporter atp-binding protein
CY657_RS03655	COG2888	peptidyl-tyrosine sulfation
CY657_RS03670	COG1466	dna polymerase III delta subunit
CY657_RS03690	COG0799	negative regulation of ribosome biogenesis
CY657_RS03700	COG0768	penicillin binding
CY657_RS03705	COG0772	Belongs to the SEDS family
CY657_RS03710	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CY657_RS03715	COG1686	Belongs to the peptidase S11 family
CY657_RS03730	COG0583	DNA-binding transcription factor activity
CY657_RS03745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CY657_RS03770	COG3069	C4-dicarboxylate transmembrane transporter activity
CY657_RS03775	COG3719	Belongs to the RNase T2 family
CY657_RS03780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CY657_RS03800	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CY657_RS03805	COG0583	DNA-binding transcription factor activity
CY657_RS03810	COG3969	phosphoadenosine phosphosulfate
CY657_RS03815	COG1475	DNA binding
CY657_RS03820	COG0436	Aminotransferase
CY657_RS03845	COG1129	ABC transporter
CY657_RS03850	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS03855	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS03865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY657_RS03880	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CY657_RS03890	COG0402	S-adenosylhomocysteine deaminase activity
CY657_RS03900	COG0483	inositol monophosphate 1-phosphatase activity
CY657_RS03905	COG2271	Major facilitator Superfamily
CY657_RS03935	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS03940	COG1129	ABC transporter
CY657_RS03945	COG0371	Dehydrogenase
CY657_RS03950	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS03965	COG2879	small protein
CY657_RS03970	COG1966	Carbon starvation protein
CY657_RS03980	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS03985	COG3433	isochorismatase activity
CY657_RS03985	COG1535	isochorismatase
CY657_RS03990	COG1021	2,3-dihydroxybenzoate-AMP ligase
CY657_RS03995	COG1169	isochorismate synthase
CY657_RS04000	COG4592	Periplasmic binding protein
CY657_RS04010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS04015	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS04020	COG1120	ATPase activity
CY657_RS04025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CY657_RS04025	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CY657_RS04030	COG3251	PFAM MbtH domain protein
CY657_RS04035	COG2382	esterase
CY657_RS04040	COG4771	TonB-dependent receptor
CY657_RS04045	COG2977	Belongs to the P-Pant transferase superfamily
CY657_RS04050	COG3958	Transketolase
CY657_RS04055	COG3959	Transketolase, thiamine diphosphate binding domain
CY657_RS04065	COG2390	Transcriptional regulator
CY657_RS04070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CY657_RS04075	COG1879	ABC-type sugar transport system periplasmic component
CY657_RS04085	COG1129	ABC transporter
CY657_RS04090	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS04100	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS04110	COG0583	DNA-binding transcription factor activity
CY657_RS04115	COG0668	transmembrane transport
CY657_RS04125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CY657_RS04155	COG0747	negative chemotaxis
CY657_RS04160	COG0601	transmembrane transport
CY657_RS04165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS04170	COG0444	Belongs to the ABC transporter superfamily
CY657_RS04175	COG4608	Belongs to the ABC transporter superfamily
CY657_RS04195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY657_RS04200	COG4221	oxidoreductase activity
CY657_RS04210	COG4215	(ABC) transporter
CY657_RS04220	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CY657_RS04235	COG0697	spore germination
CY657_RS04250	COG4608	Belongs to the ABC transporter superfamily
CY657_RS04255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS04265	COG4166	transmembrane transport
CY657_RS04275	COG3698	Phosphodiester glycosidase
CY657_RS04320	COG2315	Protein conserved in bacteria
CY657_RS04325	COG0778	Nitroreductase
CY657_RS04335	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS04345	COG3716	PTS system mannose fructose sorbose family IID component
CY657_RS04350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CY657_RS04355	COG2222	sugar isomerase
CY657_RS04360	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CY657_RS04360	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CY657_RS04380	COG0477	Major facilitator Superfamily
CY657_RS04385	COG0668	transmembrane transport
CY657_RS04390	COG1609	Transcriptional regulator
CY657_RS04400	COG0673	inositol 2-dehydrogenase activity
CY657_RS04410	COG2211	Major facilitator Superfamily
CY657_RS04415	COG1113	amino acid transport
CY657_RS04430	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS04435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY657_RS04445	COG0531	amino acid
CY657_RS04505	COG0667	Aldo Keto reductase
CY657_RS04510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS04515	COG1473	amidohydrolase
CY657_RS04535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS04540	COG1120	ATPase activity
CY657_RS04545	COG1566	PFAM secretion protein HlyD family protein
CY657_RS04590	COG4211	Belongs to the binding-protein-dependent transport system permease family
CY657_RS04595	COG1129	ABC transporter
CY657_RS04640	COG3104	oligopeptide transport
CY657_RS04645	COG1982	Orn Lys Arg decarboxylase major
CY657_RS04650	COG0531	amino acid
CY657_RS04655	COG3710	Transcriptional regulator
CY657_RS04670	COG1560	Kdo2-lipid A biosynthetic process
CY657_RS04685	COG3188	usher protein
CY657_RS04690	COG3121	Chaperone
CY657_RS04695	COG3539	Fimbrial protein
CY657_RS04710	COG0372	Belongs to the citrate synthase family
CY657_RS04925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CY657_RS05085	COG0582	viral genome integration into host DNA
CY657_RS05105	COG2501	S4 domain
CY657_RS05115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CY657_RS05135	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CY657_RS05140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CY657_RS05155	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CY657_RS05160	COG4181	ATPase activity
CY657_RS05165	COG2755	lipolytic protein G-D-S-L family
CY657_RS05170	COG0300	oxidoreductase activity
CY657_RS05175	COG3118	belongs to the thioredoxin family
CY657_RS05185	COG0390	transport system, permease component
CY657_RS05190	COG4619	ABC transporter
CY657_RS05195	COG0330	HflC and HflK could
CY657_RS05200	COG1585	Membrane protein implicated in regulation of membrane protease activity
CY657_RS05215	COG3735	TraB family
CY657_RS05220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CY657_RS05230	COG2223	nitrite transmembrane transporter activity
CY657_RS05235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CY657_RS05235	COG4651	solute:proton antiporter activity
CY657_RS05240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS05285	COG2832	Protein of unknown function (DUF454)
CY657_RS05290	COG3923	Primosomal replication protein n
CY657_RS05305	COG1196	nuclear chromosome segregation
CY657_RS05305	COG3264	Mechanosensitive ion channel
CY657_RS05310	COG1309	transcriptional regulator
CY657_RS05315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS05320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS05335	COG0110	maltose O-acetyltransferase activity
CY657_RS05380	COG1874	Beta-galactosidase
CY657_RS05385	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CY657_RS05390	COG3833	ABC-type maltose transport systems, permease component
CY657_RS05395	COG1175	transmembrane transport
CY657_RS05400	COG2182	Extracellular solute-binding protein
CY657_RS05410	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CY657_RS05425	COG2364	Membrane
CY657_RS05455	COG3695	enzyme binding
CY657_RS05460	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CY657_RS05465	COG1946	Acyl-CoA thioesterase
CY657_RS05470	COG0004	ammonium transporteR
CY657_RS05475	COG0347	Belongs to the P(II) protein family
CY657_RS05480	COG1132	(ABC) transporter
CY657_RS05485	COG1132	(ABC) transporter
CY657_RS05490	COG1522	sequence-specific DNA binding
CY657_RS05505	COG4533	DNA binding
CY657_RS05515	COG0824	Thioesterase
CY657_RS05520	COG1555	photosystem II stabilization
CY657_RS05525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CY657_RS05530	COG0776	regulation of translation
CY657_RS05535	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CY657_RS05565	COG0271	Belongs to the BolA IbaG family
CY657_RS05570	COG3056	Lipoprotein
CY657_RS05575	COG2223	nitrite transmembrane transporter activity
CY657_RS05580	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CY657_RS05585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CY657_RS05590	COG1845	cytochrome c oxidase, subunit III
CY657_RS05595	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CY657_RS05610	COG1414	Transcriptional regulator
CY657_RS05615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CY657_RS05620	COG1053	succinate dehydrogenase
CY657_RS05630	COG1053	succinate dehydrogenase
CY657_RS05645	COG0673	inositol 2-dehydrogenase activity
CY657_RS05650	COG2814	Major facilitator Superfamily
CY657_RS05660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CY657_RS05665	COG0693	protein deglycase activity
CY657_RS05685	COG0142	geranyltranstransferase activity
CY657_RS05695	COG0667	Aldo Keto reductase
CY657_RS05700	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CY657_RS05720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CY657_RS05720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CY657_RS05730	COG4238	major outer membrane lipoprotein
CY657_RS05750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CY657_RS05755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CY657_RS05760	COG1862	Preprotein translocase
CY657_RS05780	COG0450	alkyl hydroperoxide reductase
CY657_RS05785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS05800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS05810	COG1228	amidohydrolase
CY657_RS05820	COG1335	isochorismatase
CY657_RS05825	COG0583	DNA-binding transcription factor activity
CY657_RS05830	COG0366	Alpha amylase catalytic
CY657_RS05855	COG0420	3'-5' exonuclease activity
CY657_RS05860	COG0419	ATPase involved in DNA repair
CY657_RS05865	COG1940	carbohydrate kinase activity
CY657_RS05880	COG4126	flavin adenine dinucleotide binding
CY657_RS05890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CY657_RS05895	COG3416	Protein conserved in bacteria
CY657_RS05905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CY657_RS05915	COG1785	Belongs to the alkaline phosphatase family
CY657_RS05955	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CY657_RS05960	COG1335	isochorismatase
CY657_RS05965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CY657_RS05970	COG0113	porphobilinogen synthase activity
CY657_RS05980	COG2175	clavaminate synthase activity
CY657_RS05985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS05990	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CY657_RS05995	COG4521	taurine ABC transporter
CY657_RS06000	COG2040	homocysteine
CY657_RS06005	COG0833	amino acid
CY657_RS06015	COG4303	Ethanolamine ammonia lyase large subunit
CY657_RS06020	COG4302	ethanolamine ammonia-lyase activity
CY657_RS06060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS06065	COG1126	abc transporter atp-binding protein
CY657_RS06070	COG4597	amino acid ABC transporter
CY657_RS06075	COG0765	amino acid transport
CY657_RS06090	COG3188	usher protein
CY657_RS06115	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CY657_RS06125	COG3639	organic phosphonate transmembrane transporter activity
CY657_RS06155	COG0791	NLP P60 protein
CY657_RS06195	COG2909	trisaccharide binding
CY657_RS06200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CY657_RS06205	COG0022	dehydrogenase e1 component
CY657_RS06210	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY657_RS06215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY657_RS06240	COG1070	Carbohydrate kinase
CY657_RS06245	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS06250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY657_RS06255	COG3775	system Galactitol-specific IIC component
CY657_RS06260	COG0625	glutathione transferase activity
CY657_RS06265	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CY657_RS06285	COG0579	oxidoreductase
CY657_RS06290	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS06295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CY657_RS06300	COG1113	amino acid transport
CY657_RS06305	COG1802	Transcriptional regulator
CY657_RS06325	COG2195	Cleaves the N-terminal amino acid of tripeptides
CY657_RS06330	COG0454	-acetyltransferase
CY657_RS06345	COG2991	Protein conserved in bacteria
CY657_RS06360	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CY657_RS06365	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CY657_RS06385	COG3034	peptidoglycan biosynthetic process
CY657_RS06390	COG0121	glutamine amidotransferase
CY657_RS06400	COG1960	acyl-CoA dehydrogenase activity
CY657_RS06405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CY657_RS06415	COG0583	DNA-binding transcription factor activity
CY657_RS06430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY657_RS06440	COG2226	methyltransferase
CY657_RS06450	COG1388	LysM domain
CY657_RS06450	COG0741	lytic transglycosylase activity
CY657_RS06455	COG2226	methyltransferase
CY657_RS06465	COG2814	Major facilitator Superfamily
CY657_RS06470	COG0583	DNA-binding transcription factor activity
CY657_RS06475	COG0656	L-ascorbic acid biosynthetic process
CY657_RS06515	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CY657_RS06525	COG2011	ABC-type metal ion transport system permease component
CY657_RS06530	COG1464	Belongs to the NlpA lipoprotein family
CY657_RS06540	COG1720	tRNA m6t6A37 methyltransferase activity
CY657_RS06550	COG0791	NLP P60 protein
CY657_RS06555	COG3015	lipoprotein NlpE involved in copper resistance
CY657_RS06560	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CY657_RS06575	COG4568	rho-dependent transcription termination
CY657_RS06585	COG0346	lactoylglutathione lyase activity
CY657_RS06590	COG1982	Orn Lys Arg decarboxylase major
CY657_RS06600	COG0587	DNA-directed DNA polymerase activity
CY657_RS06630	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CY657_RS06640	COG0750	zinc metalloprotease
CY657_RS06645	COG0575	Belongs to the CDS family
CY657_RS06660	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CY657_RS06685	COG0024	Methionine aminopeptidase
CY657_RS06690	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CY657_RS06705	COG3835	regulator
CY657_RS06710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY657_RS06730	COG2860	membrane
CY657_RS06750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS06755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY657_RS06760	COG1120	ATPase activity
CY657_RS06765	COG4774	siderophore transport
CY657_RS06770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY657_RS06860	COG1643	Atp-dependent helicase
CY657_RS06865	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CY657_RS06885	COG0617	tRNA 3'-terminal CCA addition
CY657_RS06890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CY657_RS06910	COG0726	polysaccharide deacetylase
CY657_RS06915	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS06920	COG0842	Transport permease protein
CY657_RS06925	COG1131	(ABC) transporter
CY657_RS06930	COG0288	reversible hydration of carbon dioxide
CY657_RS06940	COG4993	Dehydrogenase
CY657_RS06945	COG2132	Multicopper oxidase
CY657_RS06990	COG3064	Membrane
CY657_RS07005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY657_RS07010	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY657_RS07015	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CY657_RS07020	COG2186	Transcriptional regulator
CY657_RS07025	COG1113	amino acid transport
CY657_RS07030	COG2211	Major facilitator Superfamily
CY657_RS07035	COG3940	Belongs to the glycosyl hydrolase 43 family
CY657_RS07040	COG3725	Membrane protein required for beta-lactamase induction
CY657_RS07045	COG3023	N-Acetylmuramoyl-L-alanine amidase
CY657_RS07055	COG4969	Belongs to the N-Me-Phe pilin family
CY657_RS07060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CY657_RS07065	COG1459	type II secretion system
CY657_RS07090	COG0494	nUDIX hydrolase
CY657_RS07110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CY657_RS07115	COG0849	cell division
CY657_RS07140	COG0772	Belongs to the SEDS family
CY657_RS07155	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CY657_RS07160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CY657_RS07165	COG0768	penicillin binding
CY657_RS07190	COG1609	Transcriptional regulator
CY657_RS07200	COG0028	Belongs to the TPP enzyme family
CY657_RS07250	COG0738	Major facilitator superfamily
CY657_RS07260	COG0583	DNA-binding transcription factor activity
CY657_RS07265	COG2271	Major facilitator Superfamily
CY657_RS07270	COG2814	Major facilitator Superfamily
CY657_RS07290	COG1178	ABC-type Fe3 transport system permease component
CY657_RS07300	COG0586	Pfam SNARE associated Golgi protein
CY657_RS07320	COG0235	Class ii aldolase
CY657_RS07325	COG0417	DNA replication proofreading
CY657_RS07335	COG0564	pseudouridine synthase activity
CY657_RS07350	COG3493	citrate carrier protein
CY657_RS07365	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CY657_RS07370	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CY657_RS07380	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CY657_RS07430	COG0505	Belongs to the CarA family
CY657_RS07495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CY657_RS07520	COG1047	Peptidyl-prolyl cis-trans
CY657_RS07535	COG0196	riboflavin kinase activity
CY657_RS07550	COG0583	DNA-binding transcription factor activity
CY657_RS07575	COG4735	regulation of single-species biofilm formation
CY657_RS07580	COG1584	GPR1 FUN34 yaaH family protein
CY657_RS07585	COG0477	Major facilitator Superfamily
CY657_RS07590	COG0521	Mo-molybdopterin cofactor biosynthetic process
CY657_RS07595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CY657_RS07600	COG1115	amino acid carrier protein
CY657_RS07615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CY657_RS07625	COG0527	aspartate kinase activity
CY657_RS07625	COG0460	homoserine dehydrogenase
CY657_RS07635	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CY657_RS07650	COG0745	RESPONSE REGULATOR receiver
CY657_RS07655	COG4452	Inner membrane protein CreD
CY657_RS07660	COG2205	protein histidine kinase activity
CY657_RS07665	COG0745	RESPONSE REGULATOR receiver
CY657_RS07670	COG3045	CreA protein
CY657_RS07675	COG3708	Transcriptional regulator
CY657_RS07675	COG2207	Transcriptional regulator
CY657_RS07695	COG0741	lytic transglycosylase activity
CY657_RS07705	COG0488	(ABC) transporter
CY657_RS07715	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CY657_RS07720	COG0560	Phosphoserine phosphatase
CY657_RS07730	COG3726	membrane protein affecting hemolysin expression
CY657_RS07760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY657_RS07765	COG0084	hydrolase, TatD family'
CY657_RS07770	COG4667	esterase of the alpha-beta hydrolase superfamily
CY657_RS07780	COG2823	Periplasmic or secreted lipoprotein
CY657_RS07790	COG1011	Hydrolase
CY657_RS07795	COG0456	acetyltransferase
CY657_RS07800	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CY657_RS07830	COG3706	GGDEF domain
CY657_RS07835	COG4114	ferric iron reductase
CY657_RS07840	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS07840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS07845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CY657_RS07850	COG2197	response regulator
CY657_RS07855	COG2197	response regulator
CY657_RS07875	COG2966	Psort location CytoplasmicMembrane, score
CY657_RS07890	COG1484	DNA-dependent DNA replication
CY657_RS07905	COG5464	transposase or invertase
CY657_RS07915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CY657_RS07920	COG3716	PTS system mannose fructose sorbose family IID component
CY657_RS07925	COG3715	PTS system
CY657_RS07940	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CY657_RS07940	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CY657_RS07945	COG1214	PFAM Peptidase M22, glycoprotease
CY657_RS07945	COG0456	acetyltransferase
CY657_RS07955	COG1737	Transcriptional regulator
CY657_RS07960	COG0800	Aldolase
CY657_RS07965	COG3734	2-keto-3-deoxy-galactonokinase
CY657_RS07980	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CY657_RS08015	COG1846	Transcriptional regulator
CY657_RS08020	COG0179	Fumarylacetoacetate (FAA) hydrolase
CY657_RS08030	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS08035	COG3384	dioxygenase
CY657_RS08045	COG3971	2-oxopent-4-enoate hydratase activity
CY657_RS08065	COG2368	4-hydroxyphenylacetate
CY657_RS08070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CY657_RS08075	COG1966	Carbon starvation protein
CY657_RS08080	COG2879	small protein
CY657_RS08085	COG0523	cobalamin synthesis protein
CY657_RS08095	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS08100	COG5464	transposase or invertase
CY657_RS08105	COG2207	Transcriptional regulator
CY657_RS08105	COG1917	Cupin 2, conserved barrel domain protein
CY657_RS08115	COG2733	membrane
CY657_RS08130	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CY657_RS08135	COG1924	4 iron, 4 sulfur cluster binding
CY657_RS08150	COG1566	PFAM secretion protein HlyD family protein
CY657_RS08160	COG5457	Domain of unknown function (DUF1127)
CY657_RS08165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY657_RS08175	COG0583	DNA-binding transcription factor activity
CY657_RS08180	COG2249	NAD(P)H dehydrogenase (quinone) activity
CY657_RS08190	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS08195	COG1129	ABC transporter
CY657_RS08200	COG1879	ABC-type sugar transport system periplasmic component
CY657_RS08210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS08215	COG0842	Transport permease protein
CY657_RS08215	COG1129	ABC transporter
CY657_RS08220	COG0842	Transport permease protein
CY657_RS08255	COG2850	peptidyl-arginine hydroxylation
CY657_RS08270	COG5002	protein histidine kinase activity
CY657_RS08275	COG0745	RESPONSE REGULATOR receiver
CY657_RS08280	COG1538	Outer membrane efflux protein
CY657_RS08285	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS08290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS08295	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS08305	COG3040	lipid binding
CY657_RS08310	COG0789	Transcriptional regulator
CY657_RS08320	COG0300	oxidoreductase activity
CY657_RS08335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CY657_RS08355	COG3272	Protein of unknown function (DUF1722)
CY657_RS08365	COG4580	involved in the transport of maltose and maltodextrins
CY657_RS08370	COG2115	Belongs to the xylose isomerase family
CY657_RS08375	COG2211	Major facilitator Superfamily
CY657_RS08380	COG3507	Belongs to the glycosyl hydrolase 43 family
CY657_RS08400	COG1216	Glycosyl transferase, family 2
CY657_RS08455	COG1715	Restriction endonuclease
CY657_RS08470	COG2003	Belongs to the UPF0758 family
CY657_RS08495	COG2378	regulation of single-species biofilm formation
CY657_RS08500	COG3596	GTP binding
CY657_RS08550	COG0210	DNA helicase
CY657_RS08555	COG1205	dead DEAH box helicase
CY657_RS08555	COG1111	helicase
CY657_RS08570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CY657_RS08600	COG0582	viral genome integration into host DNA
CY657_RS08620	COG0288	reversible hydration of carbon dioxide
CY657_RS08625	COG0659	secondary active sulfate transmembrane transporter activity
CY657_RS08630	COG1064	alcohol dehydrogenase
CY657_RS08635	COG1175	transmembrane transport
CY657_RS08640	COG0395	ABC-type sugar transport system, permease component
CY657_RS08645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CY657_RS08650	COG3842	ATPase activity
CY657_RS08665	COG1082	Xylose isomerase domain protein TIM barrel
CY657_RS08675	COG3962	Belongs to the TPP enzyme family
CY657_RS08680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS08685	COG0837	glucose binding
CY657_RS08685	COG1737	Transcriptional regulator
CY657_RS08700	COG3718	enzyme involved in inositol metabolism
CY657_RS08715	COG0433	COG0433 Predicted ATPase
CY657_RS08720	COG0795	lipopolysaccharide-transporting ATPase activity
CY657_RS08725	COG0795	lipopolysaccharide-transporting ATPase activity
CY657_RS08740	COG2927	DNA polymerase III (CHI subunit)
CY657_RS08745	COG0525	valine-tRNA ligase activity
CY657_RS08770	COG2188	Transcriptional regulator
CY657_RS08775	COG1288	antiporter activity
CY657_RS08780	COG1228	amidohydrolase
CY657_RS08785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS08790	COG2222	sugar isomerase
CY657_RS08795	COG2731	YhcH YjgK YiaL family protein
CY657_RS08835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS08835	COG1263	PTS System
CY657_RS08840	COG0366	Alpha amylase catalytic
CY657_RS08845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS08850	COG1486	melibiose metabolic process
CY657_RS08870	COG0602	queuosine metabolic process
CY657_RS08875	COG2026	Addiction module toxin, RelE StbE family
CY657_RS08880	COG3077	Addiction module antitoxin, RelB DinJ family
CY657_RS08885	COG3711	transcriptional antiterminator
CY657_RS08885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS08905	COG3964	amidohydrolase
CY657_RS08940	COG0312	modulator of DNA gyrase
CY657_RS08960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CY657_RS08970	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS08975	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS08980	COG1129	ABC transporter
CY657_RS08985	COG1879	ABC-type sugar transport system periplasmic component
CY657_RS09005	COG2105	PFAM AIG2 family protein
CY657_RS09010	COG2911	Protein conserved in bacteria
CY657_RS09015	COG0729	surface antigen
CY657_RS09025	COG1253	flavin adenine dinucleotide binding
CY657_RS09040	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CY657_RS09055	COG1733	regulation of RNA biosynthetic process
CY657_RS09060	COG0702	epimerase
CY657_RS09070	COG0697	spore germination
CY657_RS09080	COG1113	amino acid transport
CY657_RS09085	COG0545	Peptidyl-prolyl cis-trans isomerase
CY657_RS09090	COG3061	Opacity-associated protein A
CY657_RS09100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CY657_RS09105	COG2965	DNA replication, synthesis of RNA primer
CY657_RS09165	COG1073	alpha beta
CY657_RS09170	COG3650	response to hydrogen peroxide
CY657_RS09180	COG1960	acyl-CoA dehydrogenase activity
CY657_RS09185	COG0754	glutathionylspermidine amidase activity
CY657_RS09195	COG3766	membrane
CY657_RS09205	COG1842	Phage shock protein A
CY657_RS09210	COG3789	protein conserved in bacteria
CY657_RS09215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY657_RS09220	COG0557	exoribonuclease II activity
CY657_RS09235	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CY657_RS09245	COG0330	HflC and HflK could
CY657_RS09250	COG0330	HflC and HflK could
CY657_RS09255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CY657_RS09275	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY657_RS09280	COG0802	atpase or kinase
CY657_RS09285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CY657_RS09285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CY657_RS09290	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CY657_RS09315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS09340	COG3264	Mechanosensitive ion channel
CY657_RS09340	COG1511	domain protein
CY657_RS09355	COG1053	succinate dehydrogenase
CY657_RS09360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CY657_RS09380	COG2076	Multidrug Resistance protein
CY657_RS09385	COG5510	response to toxic substance
CY657_RS09400	COG1509	lysine 2,3-aminomutase activity
CY657_RS09405	COG0745	RESPONSE REGULATOR receiver
CY657_RS09440	COG3188	usher protein
CY657_RS09445	COG3539	Fimbrial protein
CY657_RS09470	COG0531	amino acid
CY657_RS09475	COG3030	protein affecting phage T7 exclusion by the F plasmid
CY657_RS09485	COG1027	Aspartate ammonia-lyase
CY657_RS09490	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CY657_RS09505	COG1309	transcriptional regulator
CY657_RS09555	COG0457	Tetratricopeptide repeat
CY657_RS09560	COG0726	polysaccharide deacetylase
CY657_RS09560	COG1649	PFAM Uncharacterised BCR, COG1649
CY657_RS09565	COG1215	transferase activity, transferring glycosyl groups
CY657_RS09585	COG0861	Integral membrane protein TerC family
CY657_RS09615	COG1486	melibiose metabolic process
CY657_RS09625	COG2169	Transcriptional regulator
CY657_RS09640	COG2824	Alkylphosphonate utilization operon protein PhnA
CY657_RS09645	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CY657_RS09650	COG2188	Transcriptional regulator
CY657_RS09655	COG3624	Phosphonate C-P lyase system protein PhnG
CY657_RS09660	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CY657_RS09665	COG3626	phosphonate metabolism
CY657_RS09670	COG3627	carbon phosphorus lyase activity
CY657_RS09675	COG4107	phosphonate C-P lyase system protein PhnK
CY657_RS09680	COG4778	phosphonate C-P lyase system protein PhnL
CY657_RS09685	COG3454	Phosphonate metabolism
CY657_RS09695	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CY657_RS09705	COG4191	Histidine kinase
CY657_RS09705	COG0784	Response regulator, receiver
CY657_RS09710	COG1129	ABC transporter
CY657_RS09715	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS09750	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CY657_RS09755	COG1301	dicarboxylic acid transport
CY657_RS09765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CY657_RS09775	COG3162	membrane
CY657_RS09805	COG3539	Fimbrial protein
CY657_RS09810	COG1346	cytolysis
CY657_RS09815	COG1380	Effector of murein hydrolase LrgA
CY657_RS09820	COG0583	DNA-binding transcription factor activity
CY657_RS09825	COG0025	NhaP-type Na H and K H
CY657_RS09830	COG2252	PERMEase
CY657_RS09835	COG0625	glutathione transferase activity
CY657_RS09840	COG0789	Transcriptional regulator
CY657_RS09850	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CY657_RS09885	COG1234	tRNA 3'-trailer cleavage
CY657_RS09890	COG1609	Transcriptional regulator
CY657_RS09895	COG0483	inositol monophosphate 1-phosphatase activity
CY657_RS09910	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CY657_RS09930	COG4771	TonB-dependent receptor
CY657_RS09935	COG0741	lytic transglycosylase activity
CY657_RS09955	COG2315	Protein conserved in bacteria
CY657_RS09960	COG0432	Pfam Uncharacterised protein family UPF0047
CY657_RS09975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CY657_RS09980	COG0305	Participates in initiation and elongation during chromosome replication
CY657_RS09995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CY657_RS10005	COG0735	belongs to the Fur family
CY657_RS10010	COG3237	CsbD-like
CY657_RS10015	COG0534	Mate efflux family protein
CY657_RS10025	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CY657_RS10100	COG0251	oxidation-reduction process
CY657_RS10110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CY657_RS10130	COG0527	aspartate kinase activity
CY657_RS10185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CY657_RS10215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CY657_RS10225	COG0456	acetyltransferase
CY657_RS10265	COG0151	Belongs to the GarS family
CY657_RS10275	COG4191	Histidine kinase
CY657_RS10280	COG3678	ATP-independent chaperone mediated protein folding
CY657_RS10315	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CY657_RS10330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CY657_RS10335	COG2104	thiamine diphosphate biosynthetic process
CY657_RS10355	COG3706	GGDEF domain
CY657_RS10365	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS10370	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CY657_RS10410	COG0250	Participates in transcription elongation, termination and antitermination
CY657_RS10460	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CY657_RS10495	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CY657_RS10505	COG1739	Uncharacterized protein family UPF0029
CY657_RS10550	COG0805	protein transport
CY657_RS10570	COG3165	ubiquinone biosynthetic process from chorismate
CY657_RS10595	COG0641	radical SAM
CY657_RS10605	COG2149	membrane
CY657_RS10610	COG2188	Transcriptional regulator
CY657_RS10630	COG0583	DNA-binding transcription factor activity
CY657_RS10635	COG0697	spore germination
CY657_RS10640	COG0561	phosphatase activity
CY657_RS10645	COG2267	carboxylic ester hydrolase activity
CY657_RS10650	COG1280	lysine exporter protein (LysE YggA)
CY657_RS10660	COG1280	lysine exporter protein (LysE YggA)
CY657_RS10695	COG0210	DNA helicase
CY657_RS10700	COG1011	Hydrolase
CY657_RS10730	COG3072	Adenylate cyclase
CY657_RS10745	COG2959	enzyme of heme biosynthesis
CY657_RS10750	COG3071	HemY protein
CY657_RS10795	COG2244	polysaccharide biosynthetic process
CY657_RS10800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CY657_RS10805	COG0456	acetyltransferase
CY657_RS10810	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CY657_RS10815	COG1088	dTDP-glucose 4,6-dehydratase activity
CY657_RS10820	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CY657_RS10825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CY657_RS10835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CY657_RS10840	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CY657_RS10850	COG3118	belongs to the thioredoxin family
CY657_RS10880	COG1811	Na channel or pump
CY657_RS10890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CY657_RS10895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CY657_RS10905	COG0583	DNA-binding transcription factor activity
CY657_RS10910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CY657_RS10925	COG3978	acetolactate synthase activity
CY657_RS10950	COG3085	chromosome segregation
CY657_RS11025	COG0583	DNA-binding transcription factor activity
CY657_RS11050	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CY657_RS11065	COG3443	Belongs to the bacterial solute-binding protein 9 family
CY657_RS11070	COG2207	Transcriptional regulator
CY657_RS11080	COG0371	Dehydrogenase
CY657_RS11085	COG0697	spore germination
CY657_RS11095	COG0583	DNA-binding transcription factor activity
CY657_RS11110	COG0737	Belongs to the 5'-nucleotidase family
CY657_RS11120	COG0460	homoserine dehydrogenase
CY657_RS11120	COG0527	aspartate kinase activity
CY657_RS11125	COG0626	cystathionine gamma-synthase activity
CY657_RS11140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CY657_RS11145	COG1609	Transcriptional regulator
CY657_RS11150	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CY657_RS11165	COG1575	Belongs to the MenA family. Type 1 subfamily
CY657_RS11185	COG3678	ATP-independent chaperone mediated protein folding
CY657_RS11190	COG0745	RESPONSE REGULATOR receiver
CY657_RS11195	COG2205	protein histidine kinase activity
CY657_RS11200	COG2258	MOSC domain
CY657_RS11205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CY657_RS11250	COG1129	ABC transporter
CY657_RS11255	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS11260	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS11265	COG1454	alcohol dehydrogenase
CY657_RS11275	COG2211	Major facilitator Superfamily
CY657_RS11335	COG0205	6-phosphofructokinase activity
CY657_RS11355	COG3383	formate dehydrogenase (NAD+) activity
CY657_RS11355	COG0243	molybdopterin cofactor binding
CY657_RS11360	COG0243	molybdopterin cofactor binding
CY657_RS11360	COG3383	formate dehydrogenase (NAD+) activity
CY657_RS11365	COG0437	4 iron, 4 sulfur cluster binding
CY657_RS11370	COG2864	formate dehydrogenase
CY657_RS11385	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CY657_RS11395	COG0456	acetyltransferase
CY657_RS11410	COG1011	Hydrolase
CY657_RS11430	COG3852	Histidine kinase
CY657_RS11440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CY657_RS11470	COG0204	Acyl-transferase
CY657_RS11480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CY657_RS11485	COG3084	Protein conserved in bacteria
CY657_RS11495	COG1763	Mo-molybdopterin cofactor biosynthetic process
CY657_RS11525	COG2186	Transcriptional regulator
CY657_RS11530	COG0477	Major facilitator Superfamily
CY657_RS11535	COG1609	Transcriptional regulator
CY657_RS11540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS11550	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS11555	COG1129	ABC transporter
CY657_RS11585	COG1522	sequence-specific DNA binding
CY657_RS11590	COG0716	FMN binding
CY657_RS11605	COG3312	ion transport
CY657_RS11655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CY657_RS11660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CY657_RS11665	COG0573	inorganic phosphate transmembrane transporter activity
CY657_RS11670	COG0581	inorganic phosphate transmembrane transporter activity
CY657_RS11675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CY657_RS11680	COG0704	Plays a role in the regulation of phosphate uptake
CY657_RS11695	COG2382	esterase
CY657_RS11700	COG0363	glucosamine-6-phosphate deaminase activity
CY657_RS11705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS11715	COG2252	PERMEase
CY657_RS11720	COG0431	NADPH-dependent FMN reductase
CY657_RS11725	COG2091	lysine biosynthetic process via aminoadipic acid
CY657_RS11760	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CY657_RS11795	COG0187	DNA topoisomerase II activity
CY657_RS11800	COG0561	phosphatase activity
CY657_RS11815	COG2186	Transcriptional regulator
CY657_RS11820	COG3734	2-keto-3-deoxy-galactonokinase
CY657_RS11825	COG0800	Aldolase
CY657_RS11835	COG2271	Major facilitator Superfamily
CY657_RS11840	COG0823	Involved in the tonB-independent uptake of proteins
CY657_RS11845	COG5645	(Lipo)protein
CY657_RS11860	COG3645	SOS response
CY657_RS11870	COG2188	Transcriptional regulator
CY657_RS11885	COG2149	membrane
CY657_RS11905	COG2610	gluconate transmembrane transporter activity
CY657_RS11910	COG0583	DNA-binding transcription factor activity
CY657_RS11915	COG2814	Major facilitator Superfamily
CY657_RS11940	COG0028	Belongs to the TPP enzyme family
CY657_RS11945	COG0440	acetolactate synthase activity
CY657_RS11950	COG2197	response regulator
CY657_RS11960	COG2271	Major facilitator Superfamily
CY657_RS12010	COG2188	Transcriptional regulator
CY657_RS12035	COG4580	involved in the transport of maltose and maltodextrins
CY657_RS12040	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS12045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS12045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS12055	COG1609	Transcriptional regulator
CY657_RS12065	COG3384	dioxygenase
CY657_RS12070	COG0583	DNA-binding transcription factor activity
CY657_RS12075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CY657_RS12080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CY657_RS12085	COG2828	Protein conserved in bacteria
CY657_RS12100	COG0697	spore germination
CY657_RS12105	COG1263	PTS System
CY657_RS12105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS12115	COG2814	Major facilitator Superfamily
CY657_RS12125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS12160	COG0583	DNA-binding transcription factor activity
CY657_RS12185	COG1464	Belongs to the NlpA lipoprotein family
CY657_RS12200	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CY657_RS12210	COG1064	alcohol dehydrogenase
CY657_RS12245	COG2211	Major facilitator Superfamily
CY657_RS12250	COG1501	Belongs to the glycosyl hydrolase 31 family
CY657_RS12260	COG1486	melibiose metabolic process
CY657_RS12265	COG1263	PTS System
CY657_RS12265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS12270	COG2982	Protein involved in outer membrane biogenesis
CY657_RS12275	COG2233	PERMEase
CY657_RS12280	COG0786	glutamate:sodium symporter activity
CY657_RS12300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CY657_RS12325	COG3152	Membrane
CY657_RS12335	COG1494	fructose-1,6-bisphosphatase
CY657_RS12340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CY657_RS12345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY657_RS12350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CY657_RS12370	COG2860	membrane
CY657_RS12380	COG2169	Transcriptional regulator
CY657_RS12380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CY657_RS12385	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CY657_RS12390	COG1561	YicC-like family, N-terminal region
CY657_RS12410	COG1131	(ABC) transporter
CY657_RS12415	COG0842	Transport permease protein
CY657_RS12445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CY657_RS12480	COG1519	Transferase
CY657_RS12485	COG1216	Glycosyl transferase, family 2
CY657_RS12490	COG0438	transferase activity, transferring glycosyl groups
CY657_RS12500	COG0859	PFAM glycosyl transferase family 9
CY657_RS12525	COG0859	PFAM glycosyl transferase family 9
CY657_RS12540	COG0156	8-amino-7-oxononanoate synthase activity
CY657_RS12550	COG0463	Glycosyl transferase, family 2
CY657_RS12555	COG2861	carbohydrate metabolic process
CY657_RS12560	COG4942	peptidase
CY657_RS12570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CY657_RS12575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CY657_RS12595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CY657_RS12605	COG2186	Transcriptional regulator
CY657_RS12625	COG3722	fumarate hydratase activity
CY657_RS12645	COG0625	glutathione transferase activity
CY657_RS12655	COG3276	selenocysteine insertion sequence binding
CY657_RS12660	COG1414	Transcriptional regulator
CY657_RS12665	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS12670	COG3977	Valine--pyruvate aminotransferase
CY657_RS12675	COG0366	Alpha amylase catalytic
CY657_RS12685	COG2992	FlgJ-related protein
CY657_RS12690	COG2207	Transcriptional regulator
CY657_RS12690	COG1609	Transcriptional regulator
CY657_RS12695	COG4214	carbohydrate transport
CY657_RS12705	COG4213	ABC transporter substrate-binding protein
CY657_RS12725	COG4682	membrane
CY657_RS12730	COG4682	membrane
CY657_RS12735	COG3274	enterobacterial common antigen metabolic process
CY657_RS12770	COG1278	Cold shock
CY657_RS12775	COG2944	sequence-specific DNA binding
CY657_RS12780	COG2814	Major facilitator Superfamily
CY657_RS12805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS12815	COG1609	Transcriptional regulator
CY657_RS12820	COG2885	chlorophyll binding
CY657_RS12825	COG0243	molybdopterin cofactor binding
CY657_RS12830	COG0456	acetyltransferase
CY657_RS12835	COG2818	Glycosylase
CY657_RS12840	COG5571	outer membrane autotransporter
CY657_RS12845	COG2223	nitrite transmembrane transporter activity
CY657_RS12885	COG0747	negative chemotaxis
CY657_RS12890	COG0601	transmembrane transport
CY657_RS12895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS12900	COG0444	Belongs to the ABC transporter superfamily
CY657_RS12905	COG4608	Belongs to the ABC transporter superfamily
CY657_RS12920	COG2894	cell division
CY657_RS12935	COG0457	Tetratricopeptide repeat
CY657_RS12950	COG2194	sulfuric ester hydrolase activity
CY657_RS12980	COG1215	transferase activity, transferring glycosyl groups
CY657_RS12985	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CY657_RS12990	COG0457	Tetratricopeptide repeat
CY657_RS12990	COG3118	belongs to the thioredoxin family
CY657_RS12995	COG2199	diguanylate cyclase activity
CY657_RS12995	COG2200	EAL domain
CY657_RS13010	COG0612	Peptidase, M16
CY657_RS13025	COG2982	Protein involved in outer membrane biogenesis
CY657_RS13030	COG0477	Major facilitator Superfamily
CY657_RS13035	COG1295	ribonuclease BN
CY657_RS13040	COG0583	DNA-binding transcription factor activity
CY657_RS13045	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS13050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY657_RS13060	COG1454	alcohol dehydrogenase
CY657_RS13070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY657_RS13075	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CY657_RS13080	COG0671	phosphoesterase, PA-phosphatase related
CY657_RS13100	COG0589	response to stress
CY657_RS13110	COG0306	phosphate transporter
CY657_RS13115	COG2081	HI0933 family
CY657_RS13120	COG2239	Acts as a magnesium transporter
CY657_RS13130	COG1124	(ABC) transporter
CY657_RS13140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS13145	COG0601	transmembrane transport
CY657_RS13150	COG0747	negative chemotaxis
CY657_RS13165	COG3479	Phenolic acid decarboxylase
CY657_RS13205	COG0628	permease
CY657_RS13210	COG0477	Major facilitator Superfamily
CY657_RS13220	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CY657_RS13235	COG3714	YhhN family
CY657_RS13245	COG3776	membrane
CY657_RS13250	COG0742	ribosomal rna small subunit methyltransferase
CY657_RS13255	COG0552	protein localization to endoplasmic reticulum
CY657_RS13260	COG2884	Cell division ATP-binding protein ftsE
CY657_RS13265	COG2177	Part of the ABC transporter FtsEX involved in
CY657_RS13280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CY657_RS13290	COG0683	leucine binding
CY657_RS13305	COG0683	leucine binding
CY657_RS13310	COG0559	Belongs to the binding-protein-dependent transport system permease family
CY657_RS13360	COG0584	glycerophosphoryl diester phosphodiesterase
CY657_RS13370	COG0405	Gamma-glutamyltransferase
CY657_RS13375	COG1247	-acetyltransferase
CY657_RS13385	COG0673	inositol 2-dehydrogenase activity
CY657_RS13390	COG1741	Belongs to the pirin family
CY657_RS13395	COG1609	Transcriptional regulator
CY657_RS13400	COG3265	gluconokinase activity
CY657_RS13405	COG2610	gluconate transmembrane transporter activity
CY657_RS13415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CY657_RS13440	COG0058	SHG alpha-glucan phosphorylase activity
CY657_RS13455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CY657_RS13470	COG1349	DNA-binding transcription factor activity
CY657_RS13485	COG0058	SHG alpha-glucan phosphorylase activity
CY657_RS13490	COG1640	4-alpha-glucanotransferase
CY657_RS13495	COG2610	gluconate transmembrane transporter activity
CY657_RS13505	COG1040	competence protein
CY657_RS13530	COG1918	ferrous iron import across plasma membrane
CY657_RS13535	COG2183	response to ionizing radiation
CY657_RS13540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CY657_RS13565	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CY657_RS13570	COG1011	Hydrolase
CY657_RS13580	COG0494	nUDIX hydrolase
CY657_RS13585	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CY657_RS13610	COG4796	Type ii and iii secretion system protein
CY657_RS13630	COG3266	domain, Protein
CY657_RS13635	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CY657_RS13640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CY657_RS13665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CY657_RS13670	COG0402	S-adenosylhomocysteine deaminase activity
CY657_RS13675	COG0738	Major facilitator superfamily
CY657_RS13700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CY657_RS13705	COG1289	transmembrane transporter activity
CY657_RS13720	COG1765	OsmC-like protein
CY657_RS13725	COG3954	Phosphoribulokinase
CY657_RS13735	COG0429	hydrolase of the alpha beta-hydrolase fold
CY657_RS13745	COG0488	(ABC) transporter
CY657_RS13765	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CY657_RS13770	COG1047	Peptidyl-prolyl cis-trans
CY657_RS13780	COG0545	Peptidyl-prolyl cis-trans isomerase
CY657_RS13785	COG2964	Protein conserved in bacteria
CY657_RS13845	COG0051	transcription antitermination factor activity, RNA binding
CY657_RS13870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CY657_RS13885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CY657_RS13950	COG0201	protein transport
CY657_RS13975	COG0202	RNA polymerase activity
CY657_RS13990	COG0789	Transcriptional regulator
CY657_RS13995	COG3036	rescue of stalled ribosome
CY657_RS14025	COG0758	DNA mediated transformation
CY657_RS14035	COG0551	DNA topoisomerase type I activity
CY657_RS14055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CY657_RS14095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS14100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS14105	COG1309	transcriptional regulator
CY657_RS14130	COG4145	pantothenate transmembrane transporter activity
CY657_RS14135	COG3924	membrane
CY657_RS14140	COG0439	Biotin carboxylase
CY657_RS14145	COG0511	ligase activity, forming carbon-carbon bonds
CY657_RS14175	COG2199	diguanylate cyclase activity
CY657_RS14175	COG2200	EAL domain
CY657_RS14185	COG1077	Cell shape determining protein MreB Mrl
CY657_RS14190	COG1792	Involved in formation and maintenance of cell shape
CY657_RS14195	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CY657_RS14205	COG1530	ribonuclease E activity
CY657_RS14210	COG3164	Protein of unknown function
CY657_RS14215	COG0312	modulator of DNA gyrase
CY657_RS14220	COG0583	DNA-binding transcription factor activity
CY657_RS14235	COG1289	transmembrane transporter activity
CY657_RS14240	COG2732	(Barnase) inhibitor
CY657_RS14265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY657_RS14270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY657_RS14275	COG3105	Protein conserved in bacteria
CY657_RS14280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CY657_RS14300	COG0625	glutathione transferase activity
CY657_RS14305	COG2969	positive regulation of protein catabolic process
CY657_RS14315	COG0493	'glutamate synthase
CY657_RS14320	COG0067	glutamate synthase
CY657_RS14320	COG0070	glutamate synthase
CY657_RS14320	COG0069	glutamate synthase activity
CY657_RS14330	COG1242	4 iron, 4 sulfur cluster binding
CY657_RS14335	COG2271	Major facilitator Superfamily
CY657_RS14340	COG1063	alcohol dehydrogenase
CY657_RS14345	COG1312	Catalyzes the dehydration of D-mannonate
CY657_RS14350	COG2198	Histidine kinase
CY657_RS14350	COG0784	Response regulator, receiver
CY657_RS14350	COG5002	protein histidine kinase activity
CY657_RS14355	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CY657_RS14360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY657_RS14365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS14375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS14380	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CY657_RS14385	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CY657_RS14390	COG1137	ATPase activity
CY657_RS14395	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CY657_RS14400	COG3117	lipopolysaccharide transmembrane transporter activity
CY657_RS14405	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CY657_RS14415	COG0530	calcium, potassium:sodium antiporter activity
CY657_RS14425	COG1127	ABC transporter
CY657_RS14430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CY657_RS14435	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CY657_RS14440	COG2854	intermembrane phospholipid transfer
CY657_RS14445	COG3113	response to antibiotic
CY657_RS14450	COG5007	Belongs to the BolA IbaG family
CY657_RS14460	COG3423	Transcriptional regulator
CY657_RS14465	COG0142	geranyltranstransferase activity
CY657_RS14480	COG0697	spore germination
CY657_RS14490	COG2027	D-alanyl-D-alanine carboxypeptidase
CY657_RS14500	COG1534	Rna-binding protein
CY657_RS14510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CY657_RS14515	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CY657_RS14525	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CY657_RS14565	COG0195	Participates in both transcription termination and antitermination
CY657_RS14615	COG0814	amino acid
CY657_RS14640	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CY657_RS14685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS14690	COG0826	peptidase U32
CY657_RS14695	COG0826	peptidase U32
CY657_RS14700	COG3154	lipid carrier protein
CY657_RS14705	COG3153	acetyltransferase
CY657_RS14720	COG0693	protein deglycase activity
CY657_RS14725	COG0702	epimerase
CY657_RS14730	COG0701	Predicted permease
CY657_RS14735	COG2823	Periplasmic or secreted lipoprotein
CY657_RS14755	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CY657_RS14760	COG2721	sulfolactate sulfo-lyase activity
CY657_RS14765	COG2271	Major facilitator Superfamily
CY657_RS14775	COG2084	Dehydrogenase
CY657_RS14780	COG1929	Belongs to the glycerate kinase type-1 family
CY657_RS14800	COG1741	Belongs to the pirin family
CY657_RS14805	COG0583	DNA-binding transcription factor activity
CY657_RS14810	COG3152	Membrane
CY657_RS14815	COG0435	Glutathione S-transferase
CY657_RS14820	COG2259	Doxx family
CY657_RS14830	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CY657_RS14835	COG4575	ribosome binding
CY657_RS14840	COG1422	Protein of unknown function (DUF1090)
CY657_RS14850	COG0586	Pfam SNARE associated Golgi protein
CY657_RS14860	COG2186	Transcriptional regulator
CY657_RS14865	COG2271	Major facilitator Superfamily
CY657_RS14875	COG2721	sulfolactate sulfo-lyase activity
CY657_RS14890	COG0861	Integral membrane protein TerC family
CY657_RS14895	COG0673	inositol 2-dehydrogenase activity
CY657_RS14900	COG1451	nucleotide metabolic process
CY657_RS14920	COG0446	pyridine nucleotide-disulphide oxidoreductase
CY657_RS14920	COG1902	pentaerythritol trinitrate reductase activity
CY657_RS14975	COG1695	Transcriptional regulator
CY657_RS14980	COG2375	cellular response to nickel ion
CY657_RS14995	COG1461	Dihydroxyacetone kinase
CY657_RS15000	COG2376	Dihydroxyacetone kinase
CY657_RS15075	COG3247	response to pH
CY657_RS15090	COG2197	response regulator
CY657_RS15110	COG0582	viral genome integration into host DNA
CY657_RS15180	COG4695	Portal protein
CY657_RS15340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CY657_RS15345	COG0358	DNA primase activity
CY657_RS15350	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CY657_RS15415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CY657_RS15430	COG4991	sh3 domain protein
CY657_RS15435	COG3025	triphosphatase activity
CY657_RS15455	COG2960	long-chain fatty acid transporting porin activity
CY657_RS15470	COG3384	dioxygenase
CY657_RS15475	COG0754	glutathionylspermidine amidase activity
CY657_RS15490	COG0494	nUDIX hydrolase
CY657_RS15495	COG3151	Protein conserved in bacteria
CY657_RS15500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CY657_RS15505	COG3150	esterase
CY657_RS15515	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CY657_RS15520	COG2249	NAD(P)H dehydrogenase (quinone) activity
CY657_RS15525	COG0642	Histidine kinase
CY657_RS15535	COG3111	PFAM Bacterial OB fold (BOF) protein
CY657_RS15540	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CY657_RS15545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CY657_RS15550	COG0204	Acyl-transferase
CY657_RS15555	COG2132	Multicopper oxidase
CY657_RS15560	COG1032	radical SAM domain protein
CY657_RS15570	COG0656	L-ascorbic acid biosynthetic process
CY657_RS15575	COG1979	alcohol dehydrogenase
CY657_RS15580	COG2207	Transcriptional regulator
CY657_RS15585	COG0586	Pfam SNARE associated Golgi protein
CY657_RS15590	COG0626	cystathionine gamma-synthase activity
CY657_RS15605	COG0848	biopolymer transport protein
CY657_RS15610	COG2211	Major facilitator Superfamily
CY657_RS15635	COG0625	glutathione transferase activity
CY657_RS15645	COG0754	glutathionylspermidine amidase activity
CY657_RS15650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY657_RS15670	COG0583	DNA-binding transcription factor activity
CY657_RS15675	COG0626	cystathionine gamma-synthase activity
CY657_RS15690	COG1811	Na channel or pump
CY657_RS15700	COG1982	Orn Lys Arg decarboxylase major
CY657_RS15705	COG2211	Major facilitator Superfamily
CY657_RS15720	COG1194	a g-specific adenine glycosylase
CY657_RS15730	COG3171	Protein conserved in bacteria
CY657_RS15740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CY657_RS15755	COG0762	integral membrane protein
CY657_RS15760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CY657_RS15765	COG2805	Type II/IV secretion system protein
CY657_RS15785	COG0189	ligase activity
CY657_RS15790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CY657_RS15795	COG2356	endonuclease I
CY657_RS15805	COG2814	Major facilitator Superfamily
CY657_RS15840	COG0501	Belongs to the peptidase M48B family
CY657_RS15845	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CY657_RS15860	COG0191	fructose-bisphosphate aldolase activity
CY657_RS15865	COG0668	transmembrane transport
CY657_RS15875	COG2968	Membrane
CY657_RS15890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY657_RS15895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CY657_RS15915	COG0006	proline dipeptidase activity
CY657_RS15920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CY657_RS15925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CY657_RS15945	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS15950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CY657_RS15970	COG2723	6-phospho-beta-galactosidase activity
CY657_RS15975	COG1737	Transcriptional regulator
CY657_RS15985	COG1272	protein, Hemolysin III
CY657_RS15995	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CY657_RS16005	COG0716	FMN binding
CY657_RS16010	COG4974	Belongs to the 'phage' integrase family
CY657_RS16020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CY657_RS16045	COG4942	peptidase
CY657_RS16055	COG4974	Belongs to the 'phage' integrase family
CY657_RS16065	COG3646	Phage regulatory protein
CY657_RS16085	COG2814	Major facilitator Superfamily
CY657_RS16100	COG0667	Aldo Keto reductase
CY657_RS16140	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CY657_RS16145	COG1393	Belongs to the ArsC family
CY657_RS16160	COG1538	Outer membrane efflux protein
CY657_RS16165	COG1289	transmembrane transporter activity
CY657_RS16180	COG3592	Divergent 4Fe-4S mono-cluster
CY657_RS16185	COG2388	GCN5-related N-acetyl-transferase
CY657_RS16195	COG3539	Fimbrial protein
CY657_RS16200	COG3539	Fimbrial protein
CY657_RS16205	COG3539	Fimbrial protein
CY657_RS16210	COG3188	usher protein
CY657_RS16215	COG3121	Chaperone
CY657_RS16220	COG3539	Fimbrial protein
CY657_RS16230	COG4974	Belongs to the 'phage' integrase family
CY657_RS16235	COG0582	viral genome integration into host DNA
CY657_RS16245	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CY657_RS16250	COG1846	Transcriptional regulator
CY657_RS16255	COG0697	spore germination
CY657_RS16305	COG0667	Aldo Keto reductase
CY657_RS16310	COG0814	amino acid
CY657_RS16325	COG0183	Belongs to the thiolase family
CY657_RS16335	COG0823	Involved in the tonB-independent uptake of proteins
CY657_RS16340	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS16345	COG2814	Major facilitator Superfamily
CY657_RS16375	COG3842	ATPase activity
CY657_RS16380	COG0395	ABC-type sugar transport system, permease component
CY657_RS16385	COG1175	transmembrane transport
CY657_RS16390	COG1917	Cupin 2, conserved barrel domain protein
CY657_RS16395	COG1794	racemase activity, acting on amino acids and derivatives
CY657_RS16400	COG0583	DNA-binding transcription factor activity
CY657_RS16410	COG1609	Transcriptional regulator
CY657_RS16415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS16420	COG2723	6-phospho-beta-galactosidase activity
CY657_RS16425	COG2186	Transcriptional regulator
CY657_RS16435	COG1609	Transcriptional regulator
CY657_RS16460	COG0667	Aldo Keto reductase
CY657_RS16470	COG0861	Integral membrane protein TerC family
CY657_RS16500	COG2165	general secretion pathway protein
CY657_RS16505	COG4795	General secretion pathway protein
CY657_RS16515	COG4967	type IV pilus modification protein PilV
CY657_RS16520	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CY657_RS16525	COG1025	Belongs to the peptidase M16 family
CY657_RS16530	COG1074	ATP-dependent DNA helicase activity
CY657_RS16535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CY657_RS16545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CY657_RS16545	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CY657_RS16550	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY657_RS16555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CY657_RS16585	COG4656	Part of a membrane complex involved in electron transport
CY657_RS16590	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS16590	COG1454	alcohol dehydrogenase
CY657_RS16620	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CY657_RS16785	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CY657_RS16790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CY657_RS16795	COG2166	iron-sulfur cluster assembly
CY657_RS16800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CY657_RS16810	COG0583	DNA-binding transcription factor activity
CY657_RS16815	COG2363	Small membrane protein
CY657_RS16825	COG1349	DNA-binding transcription factor activity
CY657_RS16845	COG0738	Major facilitator superfamily
CY657_RS16850	COG0235	Class ii aldolase
CY657_RS16855	COG1454	alcohol dehydrogenase
CY657_RS16870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS16885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CY657_RS16890	COG2011	ABC-type metal ion transport system permease component
CY657_RS16895	COG1464	Belongs to the NlpA lipoprotein family
CY657_RS16905	COG0477	Major facilitator Superfamily
CY657_RS16915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY657_RS16920	COG1760	l-serine dehydratase
CY657_RS16925	COG0814	amino acid
CY657_RS16930	COG1611	Belongs to the LOG family
CY657_RS16945	COG3098	single-species biofilm formation
CY657_RS16950	COG0564	pseudouridine synthase activity
CY657_RS16955	COG0716	FMN binding
CY657_RS16960	COG2271	Major facilitator Superfamily
CY657_RS16965	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS16970	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS16975	COG1929	Belongs to the glycerate kinase type-1 family
CY657_RS16980	COG3437	response regulator, receiver
CY657_RS16980	COG2205	protein histidine kinase activity
CY657_RS16980	COG4999	Histidine kinase
CY657_RS16980	COG3850	Histidine kinase
CY657_RS16990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CY657_RS16995	COG3956	TIGRFAM MazG family protein
CY657_RS17015	COG0602	queuosine metabolic process
CY657_RS17020	COG0720	synthase
CY657_RS17040	COG2234	aminopeptidase activity
CY657_RS17100	COG1388	LysM domain
CY657_RS17100	COG4942	peptidase
CY657_RS17130	COG0163	prenyltransferase activity
CY657_RS17135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CY657_RS17180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS17185	COG4558	Periplasmic binding protein
CY657_RS17190	COG3720	iron ion transport
CY657_RS17210	COG0679	Auxin Efflux Carrier
CY657_RS17225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY657_RS17230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY657_RS17235	COG1121	(ABC) transporter
CY657_RS17245	COG1609	Transcriptional regulator
CY657_RS17250	COG1940	carbohydrate kinase activity
CY657_RS17255	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS17260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS17265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS17270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS17280	COG4580	involved in the transport of maltose and maltodextrins
CY657_RS17290	COG2723	6-phospho-beta-galactosidase activity
CY657_RS17300	COG0309	Hydrogenase expression formation protein (HypE)
CY657_RS17305	COG0409	Hydrogenase expression formation protein
CY657_RS17310	COG0298	carbon dioxide binding
CY657_RS17315	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CY657_RS17335	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS17340	COG0651	ATP synthesis coupled electron transport
CY657_RS17345	COG0650	Formate hydrogenlyase subunit 4
CY657_RS17350	COG3261	NADH dehydrogenase
CY657_RS17350	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CY657_RS17355	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY657_RS17360	COG3260	NADH ubiquinone oxidoreductase 20
CY657_RS17370	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CY657_RS17380	COG2723	6-phospho-beta-galactosidase activity
CY657_RS17385	COG1263	PTS System
CY657_RS17385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS17390	COG1609	Transcriptional regulator
CY657_RS17395	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS17400	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CY657_RS17405	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CY657_RS17435	COG1349	DNA-binding transcription factor activity
CY657_RS17440	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS17445	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS17455	COG3732	PTS system glucitol sorbitol-specific
CY657_RS17460	COG3730	PTS system glucitol sorbitol-specific
CY657_RS17465	COG2951	lytic endotransglycosylase activity
CY657_RS17475	COG1121	(ABC) transporter
CY657_RS17480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY657_RS17485	COG0803	Belongs to the bacterial solute-binding protein 9 family
CY657_RS17490	COG1546	Belongs to the CinA family
CY657_RS17515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CY657_RS17545	COG2823	Periplasmic or secreted lipoprotein
CY657_RS17550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS17555	COG1238	metal cluster binding
CY657_RS17575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CY657_RS17580	COG2814	Major facilitator Superfamily
CY657_RS17585	COG1566	PFAM secretion protein HlyD family protein
CY657_RS17590	COG1846	Transcriptional regulator
CY657_RS17600	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CY657_RS17610	COG4176	ABC-type proline glycine betaine transport system permease component
CY657_RS17625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CY657_RS17635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CY657_RS17640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS17645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY657_RS17650	COG4575	ribosome binding
CY657_RS17675	COG2916	Histone family protein nucleoid-structuring protein H-NS
CY657_RS17690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CY657_RS17695	COG0640	Transcriptional regulator
CY657_RS17705	COG0583	DNA-binding transcription factor activity
CY657_RS17710	COG3284	Transcriptional regulator
CY657_RS17720	COG3539	Fimbrial protein
CY657_RS17725	COG3121	Chaperone
CY657_RS17745	COG3188	usher protein
CY657_RS17755	COG3539	Fimbrial protein
CY657_RS17760	COG2197	response regulator
CY657_RS17775	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS17785	COG0235	Class ii aldolase
CY657_RS17795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS17830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS17835	COG3708	Transcriptional regulator
CY657_RS17835	COG2207	Transcriptional regulator
CY657_RS17915	COG0582	viral genome integration into host DNA
CY657_RS17930	COG2867	negative regulation of translational initiation
CY657_RS17945	COG0497	DNA recombination
CY657_RS17965	COG4536	flavin adenine dinucleotide binding
CY657_RS17970	COG4137	Cytochrome C assembly protein
CY657_RS17975	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CY657_RS18010	COG2885	chlorophyll binding
CY657_RS18015	COG2199	diguanylate cyclase activity
CY657_RS18025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CY657_RS18030	COG0287	Prephenate dehydrogenase
CY657_RS18030	COG1605	Chorismate mutase
CY657_RS18040	COG1605	Chorismate mutase
CY657_RS18040	COG0077	Prephenate dehydratase
CY657_RS18050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CY657_RS18055	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CY657_RS18070	COG0542	response to heat
CY657_RS18100	COG0477	Major facilitator Superfamily
CY657_RS18105	COG5544	Lipoprotein
CY657_RS18110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY657_RS18120	COG3148	PFAM DTW domain containing protein
CY657_RS18125	COG3118	belongs to the thioredoxin family
CY657_RS18130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY657_RS18145	COG0513	Belongs to the DEAD box helicase family
CY657_RS18155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CY657_RS18165	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CY657_RS18170	COG3026	antisigma factor binding
CY657_RS18175	COG3086	response to oxidative stress
CY657_RS18185	COG0681	Belongs to the peptidase S26 family
CY657_RS18205	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CY657_RS18215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS18220	COG1737	Transcriptional regulator
CY657_RS18225	COG0560	Phosphoserine phosphatase
CY657_RS18240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CY657_RS18240	COG0047	phosphoribosylformylglycinamidine synthase activity
CY657_RS18245	COG2205	protein histidine kinase activity
CY657_RS18250	COG3170	Tfp pilus assembly protein FimV
CY657_RS18255	COG2204	response regulator
CY657_RS18260	COG0347	Belongs to the P(II) protein family
CY657_RS18265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS18265	COG1017	nitric oxide dioxygenase activity
CY657_RS18280	COG2259	Doxx family
CY657_RS18285	COG1940	carbohydrate kinase activity
CY657_RS18290	COG0457	Tetratricopeptide repeat
CY657_RS18295	COG2814	Major facilitator Superfamily
CY657_RS18295	COG0477	Major facilitator Superfamily
CY657_RS18300	COG2017	converts alpha-aldose to the beta-anomer
CY657_RS18305	COG2814	Major facilitator Superfamily
CY657_RS18310	COG3711	transcriptional antiterminator
CY657_RS18315	COG3683	transport system, periplasmic component
CY657_RS18320	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CY657_RS18350	COG0822	iron-sulfur transferase activity
CY657_RS18370	COG0633	Ferredoxin
CY657_RS18375	COG2975	iron-sulfur cluster assembly
CY657_RS18395	COG2897	thiosulfate sulfurtransferase activity
CY657_RS18400	COG2373	Large extracellular alpha-helical protein
CY657_RS18405	COG4953	penicillin-binding protein 1C
CY657_RS18440	COG2976	Protein conserved in bacteria
CY657_RS18460	COG1645	bacterial-type flagellum-dependent swarming motility
CY657_RS18470	COG0516	GMP reductase activity
CY657_RS18470	COG0517	IMP dehydrogenase activity
CY657_RS18480	COG3119	arylsulfatase activity
CY657_RS18485	COG0641	radical SAM
CY657_RS18505	COG2200	EAL domain
CY657_RS18520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CY657_RS18535	COG2723	6-phospho-beta-galactosidase activity
CY657_RS18545	COG2233	PERMEase
CY657_RS18560	COG1393	Belongs to the ArsC family
CY657_RS18565	COG4783	chaperone-mediated protein folding
CY657_RS18570	COG0628	permease
CY657_RS18575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CY657_RS18580	COG2716	regulation of RNA biosynthetic process
CY657_RS18590	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CY657_RS18600	COG2321	neutral zinc metallopeptidase
CY657_RS18605	COG1444	tRNA N-acetyltransferase activity
CY657_RS18610	COG0400	carboxylic ester hydrolase activity
CY657_RS18625	COG1393	Belongs to the ArsC family
CY657_RS18635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS18645	COG0493	'glutamate synthase
CY657_RS18645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS18655	COG5342	invasion associated locus B
CY657_RS18660	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CY657_RS18665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CY657_RS18675	COG4810	utilization protein
CY657_RS18765	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY657_RS18785	COG2837	iron assimilation
CY657_RS18795	COG4150	thiosulfate binding
CY657_RS18800	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CY657_RS18805	COG4208	sulfate ABC transporter
CY657_RS18810	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CY657_RS18820	COG4319	ketosteroid isomerase
CY657_RS18855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CY657_RS18875	COG3530	Putative quorum-sensing-regulated virulence factor
CY657_RS18880	COG0385	Bile acid
CY657_RS18885	COG0583	DNA-binding transcription factor activity
CY657_RS18925	COG3415	Transposase
CY657_RS18930	COG3415	Transposase
CY657_RS18945	COG2200	EAL domain
CY657_RS18945	COG2199	diguanylate cyclase activity
CY657_RS18950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY657_RS18965	COG0667	Aldo Keto reductase
CY657_RS18970	COG3961	Belongs to the TPP enzyme family
CY657_RS18985	COG3279	Response regulator of the LytR AlgR family
CY657_RS18990	COG3275	phosphorelay sensor kinase activity
CY657_RS19000	COG0436	Aminotransferase
CY657_RS19010	COG2807	transmembrane transport
CY657_RS19015	COG0590	tRNA wobble adenosine to inosine editing
CY657_RS19020	COG0583	DNA-binding transcription factor activity
CY657_RS19040	COG2116	formate transmembrane transporter activity
CY657_RS19045	COG2853	Lipoprotein
CY657_RS19060	COG3691	Protein conserved in bacteria
CY657_RS19075	COG2062	phosphohistidine phosphatase, SixA
CY657_RS19100	COG0730	response to heat
CY657_RS19105	COG3101	peptidyl-lysine hydroxylation
CY657_RS19120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CY657_RS19140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CY657_RS19150	COG0586	Pfam SNARE associated Golgi protein
CY657_RS19160	COG0285	dihydrofolate synthase activity
CY657_RS19165	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CY657_RS19170	COG1286	toxin biosynthetic process
CY657_RS19175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CY657_RS19180	COG0163	prenyltransferase activity
CY657_RS19200	COG4160	amino acid transport
CY657_RS19205	COG4598	ABC transporter
CY657_RS19215	COG1090	epimerase
CY657_RS19220	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CY657_RS19225	COG0625	glutathione transferase activity
CY657_RS19230	COG0625	glutathione transferase activity
CY657_RS19235	COG0622	Phosphoesterase
CY657_RS19240	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CY657_RS19245	COG0280	phosphate acetyltransferase
CY657_RS19245	COG0857	belongs to the CobB CobQ family
CY657_RS19265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS19270	COG0490	domain, Protein
CY657_RS19270	COG0471	metal ion transport
CY657_RS19280	COG0436	Aminotransferase
CY657_RS19285	COG0583	DNA-binding transcription factor activity
CY657_RS19340	COG0839	Belongs to the complex I subunit 6 family
CY657_RS19350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CY657_RS19355	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY657_RS19370	COG2153	protein acetylation
CY657_RS19375	COG1169	isochorismate synthase
CY657_RS19400	COG0318	PFAM AMP-dependent synthetase and ligase
CY657_RS19410	COG5464	transposase or invertase
CY657_RS19425	COG1414	Transcriptional regulator
CY657_RS19435	COG2271	Major facilitator Superfamily
CY657_RS19445	COG0247	lactate metabolic process
CY657_RS19455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CY657_RS19460	COG2271	Major facilitator Superfamily
CY657_RS19465	COG0584	glycerophosphoryl diester phosphodiesterase
CY657_RS19475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS19505	COG0784	Response regulator, receiver
CY657_RS19505	COG2205	protein histidine kinase activity
CY657_RS19515	COG0642	Histidine kinase
CY657_RS19515	COG2198	Histidine kinase
CY657_RS19530	COG2169	Transcriptional regulator
CY657_RS19530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CY657_RS19535	COG3145	DNA-N1-methyladenine dioxygenase activity
CY657_RS19540	COG4615	Cyclic peptide transporter
CY657_RS19545	COG2239	Acts as a magnesium transporter
CY657_RS19550	COG0659	secondary active sulfate transmembrane transporter activity
CY657_RS19565	COG0628	permease
CY657_RS19590	COG1349	DNA-binding transcription factor activity
CY657_RS19595	COG0494	nUDIX hydrolase
CY657_RS19615	COG1061	Type III restriction enzyme res subunit
CY657_RS19620	COG1187	pseudouridine synthase activity
CY657_RS19625	COG2814	Major facilitator Superfamily
CY657_RS19635	COG4172	Belongs to the ABC transporter superfamily
CY657_RS19640	COG4239	(ABC) transporter, permease
CY657_RS19645	COG4174	ABC transporter (Permease)
CY657_RS19650	COG4166	transmembrane transport
CY657_RS19655	COG2200	EAL domain
CY657_RS19660	COG0791	NLP P60 protein
CY657_RS19665	COG0671	phosphoesterase, PA-phosphatase related
CY657_RS19670	COG0523	cobalamin synthesis protein
CY657_RS19675	COG0246	Mannitol dehydrogenase
CY657_RS19680	COG1312	Catalyzes the dehydration of D-mannonate
CY657_RS19705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS19705	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS19710	COG1105	Belongs to the carbohydrate kinase PfkB family
CY657_RS19715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CY657_RS19715	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CY657_RS19715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CY657_RS19725	COG2855	membrane
CY657_RS19735	COG0583	DNA-binding transcription factor activity
CY657_RS19740	COG0833	amino acid
CY657_RS19755	COG4771	TonB-dependent receptor
CY657_RS19770	COG2311	Membrane
CY657_RS19785	COG1129	ABC transporter
CY657_RS19795	COG2949	membrane
CY657_RS19810	COG1346	cytolysis
CY657_RS19820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CY657_RS19825	COG3659	wide pore channel activity
CY657_RS19840	COG2723	6-phospho-beta-galactosidase activity
CY657_RS19850	COG1538	Outer membrane efflux protein
CY657_RS19855	COG0586	Pfam SNARE associated Golgi protein
CY657_RS19865	COG1686	Belongs to the peptidase S11 family
CY657_RS19875	COG0277	FAD linked oxidase domain protein
CY657_RS19880	COG1472	Belongs to the glycosyl hydrolase 3 family
CY657_RS19885	COG1732	Glycine betaine
CY657_RS19890	COG1174	glycine betaine transport
CY657_RS19895	COG1125	glycine betaine transport
CY657_RS19900	COG1174	glycine betaine transport
CY657_RS19910	COG3275	phosphorelay sensor kinase activity
CY657_RS19920	COG4807	Protein conserved in bacteria
CY657_RS19940	COG5455	response to cobalt ion
CY657_RS19945	COG0583	DNA-binding transcription factor activity
CY657_RS19950	COG2252	PERMEase
CY657_RS19960	COG0583	DNA-binding transcription factor activity
CY657_RS19975	COG0351	phosphomethylpyrimidine kinase
CY657_RS19980	COG1830	Aldolase
CY657_RS19990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CY657_RS20015	COG1070	Carbohydrate kinase
CY657_RS20025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS20030	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS20035	COG0747	negative chemotaxis
CY657_RS20040	COG0601	transmembrane transport
CY657_RS20045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS20050	COG0444	Belongs to the ABC transporter superfamily
CY657_RS20055	COG4608	Belongs to the ABC transporter superfamily
CY657_RS20065	COG0826	peptidase U32
CY657_RS20070	COG0745	RESPONSE REGULATOR receiver
CY657_RS20075	COG2205	protein histidine kinase activity
CY657_RS20100	COG1301	dicarboxylic acid transport
CY657_RS20115	COG5002	protein histidine kinase activity
CY657_RS20120	COG0443	Heat shock 70 kDa protein
CY657_RS20130	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CY657_RS20145	COG2982	Protein involved in outer membrane biogenesis
CY657_RS20150	COG1253	flavin adenine dinucleotide binding
CY657_RS20185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CY657_RS20210	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CY657_RS20215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY657_RS20220	COG1051	belongs to the nudix hydrolase family
CY657_RS20225	COG0297	glycogen (starch) synthase activity
CY657_RS20300	COG0438	transferase activity, transferring glycosyl groups
CY657_RS20305	COG1442	glycosyl transferase family 8
CY657_RS20305	COG1216	Glycosyl transferase, family 2
CY657_RS20315	COG0463	Glycosyl transferase, family 2
CY657_RS20340	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CY657_RS20370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY657_RS20375	COG0583	DNA-binding transcription factor activity
CY657_RS20385	COG0531	amino acid
CY657_RS20390	COG0640	Transcriptional regulator
CY657_RS20395	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CY657_RS20400	COG2925	Exonuclease
CY657_RS20415	COG1289	transmembrane transporter activity
CY657_RS20435	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CY657_RS20445	COG1942	4-Oxalocrotonate Tautomerase
CY657_RS20450	COG0583	DNA-binding transcription factor activity
CY657_RS20455	COG0095	Lipoate-protein ligase
CY657_RS20460	COG0477	Major facilitator Superfamily
CY657_RS20475	COG3300	MHYT domain
CY657_RS20475	COG5001	Diguanylate cyclase
CY657_RS20485	COG3615	Tellurite resistance protein tehB
CY657_RS20510	COG3706	GGDEF domain
CY657_RS20540	COG3423	Transcriptional regulator
CY657_RS20580	COG0758	DNA mediated transformation
CY657_RS20640	COG3504	Conjugal transfer protein
CY657_RS20645	COG3736	Type IV secretory pathway, component VirB8
CY657_RS20665	COG3451	type IV secretory pathway VirB4
CY657_RS20685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CY657_RS20745	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS20750	COG4221	oxidoreductase activity
CY657_RS20755	COG2207	Transcriptional regulator
CY657_RS20765	COG1959	2 iron, 2 sulfur cluster binding
CY657_RS20775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS20780	COG0582	viral genome integration into host DNA
CY657_RS20790	COG0534	Mate efflux family protein
CY657_RS20800	COG0582	viral genome integration into host DNA
CY657_RS20915	COG2916	Histone family protein nucleoid-structuring protein H-NS
CY657_RS20950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CY657_RS20970	COG0604	alcohol dehydrogenase
CY657_RS20975	COG1309	transcriptional regulator
CY657_RS20980	COG0025	NhaP-type Na H and K H
CY657_RS21030	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CY657_RS21040	COG1418	mRNA catabolic process
CY657_RS21045	COG0270	DNA (cytosine-5-)-methyltransferase activity
CY657_RS21050	COG3727	T/G mismatch-specific endonuclease activity
CY657_RS21055	COG0697	spore germination
CY657_RS21060	COG2354	Protein conserved in bacteria
CY657_RS21090	COG0366	Alpha amylase catalytic
CY657_RS21095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS21105	COG0765	amino acid transport
CY657_RS21110	COG1126	abc transporter atp-binding protein
CY657_RS21115	COG2197	response regulator
CY657_RS21125	COG2197	response regulator
CY657_RS21165	COG3012	SEC-C Motif Domain Protein
CY657_RS21165	COG3318	Belongs to the UPF0149 family
CY657_RS21170	COG0814	amino acid
CY657_RS21180	COG1528	Iron-storage protein
CY657_RS21195	COG0477	Major facilitator Superfamily
CY657_RS21205	COG2211	Major facilitator Superfamily
CY657_RS21215	COG1528	Iron-storage protein
CY657_RS21225	COG1879	ABC-type sugar transport system periplasmic component
CY657_RS21235	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS21260	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CY657_RS21270	COG3102	Protein conserved in bacteria
CY657_RS21290	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CY657_RS21295	COG1801	Protein of unknown function DUF72
CY657_RS21300	COG1335	isochorismatase
CY657_RS21310	COG0494	nUDIX hydrolase
CY657_RS21335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY657_RS21345	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CY657_RS21350	COG0739	heme binding
CY657_RS21355	COG1560	Kdo2-lipid A biosynthetic process
CY657_RS21365	COG1737	Transcriptional regulator
CY657_RS21380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CY657_RS21385	COG0129	dihydroxy-acid dehydratase activity
CY657_RS21390	COG0800	Aldolase
CY657_RS21400	COG3141	response to X-ray
CY657_RS21405	COG2979	Protein of unknown function (DUF533)
CY657_RS21410	COG1770	oligopeptidase
CY657_RS21415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY657_RS21425	COG2372	response to copper ion
CY657_RS21430	COG1276	copper resistance
CY657_RS21445	COG2990	Protein conserved in bacteria
CY657_RS21470	COG3008	intermembrane lipid transfer
CY657_RS21475	COG2995	paraquat-inducible protein a
CY657_RS21480	COG1956	GAF domain-containing protein
CY657_RS21500	COG2814	Major facilitator Superfamily
CY657_RS21510	COG1414	Transcriptional regulator
CY657_RS21550	COG0768	penicillin binding
CY657_RS21555	COG2226	methyltransferase
CY657_RS21570	COG3716	PTS system mannose fructose sorbose family IID component
CY657_RS21575	COG3715	PTS system
CY657_RS21580	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS21580	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS21585	COG1253	flavin adenine dinucleotide binding
CY657_RS21590	COG2200	EAL domain
CY657_RS21595	COG1760	l-serine dehydratase
CY657_RS21615	COG0251	oxidation-reduction process
CY657_RS21620	COG1199	ATP-dependent helicase activity
CY657_RS21630	COG3065	identical protein binding
CY657_RS21640	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CY657_RS21650	COG2894	cell division
CY657_RS21665	COG0179	Fumarylacetoacetate (FAA) hydrolase
CY657_RS21695	COG2719	SpoVR family
CY657_RS21715	COG1619	proteins homologs of microcin C7 resistance protein MccF
CY657_RS21740	COG2308	Evidence 4 Homologs of previously reported genes of
CY657_RS21785	COG0583	DNA-binding transcription factor activity
CY657_RS21790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CY657_RS21805	COG1882	Formate acetyltransferase
CY657_RS21835	COG0583	DNA-binding transcription factor activity
CY657_RS21865	COG0583	DNA-binding transcription factor activity
CY657_RS21880	COG3122	Protein conserved in bacteria
CY657_RS21905	COG2885	chlorophyll binding
CY657_RS21965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CY657_RS21975	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CY657_RS22040	COG0012	GTP binding
CY657_RS22060	COG0659	secondary active sulfate transmembrane transporter activity
CY657_RS22095	COG2890	protein-(glutamine-N5) methyltransferase activity
CY657_RS22115	COG0387	Pfam Sodium calcium exchanger
CY657_RS22120	COG4572	Cation transport regulator
CY657_RS22125	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CY657_RS22135	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CY657_RS22140	COG3707	response regulator
CY657_RS22145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY657_RS22155	COG1116	anion transmembrane transporter activity
CY657_RS22160	COG2146	nitrite reductase [NAD(P)H] activity
CY657_RS22160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CY657_RS22165	COG0243	molybdopterin cofactor binding
CY657_RS22170	COG4932	domain protein
CY657_RS22175	COG2197	response regulator
CY657_RS22180	COG3850	Histidine kinase
CY657_RS22185	COG2223	nitrite transmembrane transporter activity
CY657_RS22190	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CY657_RS22195	COG1140	nitrate reductase beta subunit
CY657_RS22200	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CY657_RS22205	COG2181	nitrate reductase activity
CY657_RS22215	COG1522	sequence-specific DNA binding
CY657_RS22245	COG0788	formyltetrahydrofolate deformylase activity
CY657_RS22255	COG1752	Esterase of the alpha-beta hydrolase superfamily
CY657_RS22260	COG0745	RESPONSE REGULATOR receiver
CY657_RS22265	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CY657_RS22270	COG2916	Histone family protein nucleoid-structuring protein H-NS
CY657_RS22275	COG1435	thymidine kinase activity
CY657_RS22280	COG1454	alcohol dehydrogenase
CY657_RS22280	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS22290	COG2095	MarC family integral membrane protein
CY657_RS22295	COG4166	transmembrane transport
CY657_RS22300	COG0601	transmembrane transport
CY657_RS22305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS22310	COG0444	Belongs to the ABC transporter superfamily
CY657_RS22320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CY657_RS22340	COG2353	YceI-like domain
CY657_RS22345	COG2350	Protein conserved in bacteria
CY657_RS22355	COG3001	Fructosamine kinase
CY657_RS22365	COG1105	Belongs to the carbohydrate kinase PfkB family
CY657_RS22370	COG3137	Salt-induced outer membrane protein
CY657_RS22410	COG0072	phenylalanine-tRNA ligase activity
CY657_RS22410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CY657_RS22430	COG0583	DNA-binding transcription factor activity
CY657_RS22450	COG0386	Belongs to the glutathione peroxidase family
CY657_RS22460	COG0791	NLP P60 protein
CY657_RS22470	COG4256	Hemin uptake protein
CY657_RS22475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CY657_RS22485	COG0574	Belongs to the PEP-utilizing enzyme family
CY657_RS22485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CY657_RS22495	COG0628	permease
CY657_RS22500	COG0277	FAD linked oxidase domain protein
CY657_RS22500	COG0247	lactate metabolic process
CY657_RS22505	COG2050	protein possibly involved in aromatic compounds catabolism
CY657_RS22510	COG2261	transglycosylase associated protein
CY657_RS22540	COG1120	ATPase activity
CY657_RS22545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS22555	COG0583	DNA-binding transcription factor activity
CY657_RS22580	COG1304	FMN binding
CY657_RS22585	COG1309	transcriptional regulator
CY657_RS22600	COG0316	Belongs to the HesB IscA family
CY657_RS22605	COG0719	Fe-S assembly protein
CY657_RS22610	COG0396	ATPase activity
CY657_RS22615	COG0719	Fe-S assembly protein
CY657_RS22630	COG1376	ErfK ybiS ycfS ynhG family protein
CY657_RS22655	COG1309	transcriptional regulator
CY657_RS22660	COG1082	Xylose isomerase domain protein TIM barrel
CY657_RS22660	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CY657_RS22665	COG2271	Major facilitator Superfamily
CY657_RS22670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CY657_RS22680	COG1120	ATPase activity
CY657_RS22685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS22690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY657_RS22695	COG1414	Transcriptional regulator
CY657_RS22730	COG2814	Major facilitator Superfamily
CY657_RS22750	COG0583	DNA-binding transcription factor activity
CY657_RS22755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS22775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS22780	COG1116	anion transmembrane transporter activity
CY657_RS22785	COG4774	siderophore transport
CY657_RS22790	COG1120	ATPase activity
CY657_RS22795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS22800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS22820	COG0765	amino acid transport
CY657_RS22825	COG1126	abc transporter atp-binding protein
CY657_RS22855	COG1473	amidohydrolase
CY657_RS22860	COG3383	formate dehydrogenase (NAD+) activity
CY657_RS22865	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CY657_RS22880	COG1175	transmembrane transport
CY657_RS22915	COG1857	crispr-associated protein
CY657_RS22925	COG1518	maintenance of DNA repeat elements
CY657_RS22930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY657_RS22935	COG3157	Type VI secretion system effector, Hcp
CY657_RS22965	COG4133	protoheme IX ABC transporter activity
CY657_RS22970	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CY657_RS22975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CY657_RS22990	COG1138	Cytochrome C-type biogenesis protein
CY657_RS23000	COG4235	cytochrome complex assembly
CY657_RS23000	COG3088	subunit of a heme lyase
CY657_RS23020	COG5002	protein histidine kinase activity
CY657_RS23020	COG3850	Histidine kinase
CY657_RS23025	COG0745	RESPONSE REGULATOR receiver
CY657_RS23045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS23080	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS23085	COG2610	gluconate transmembrane transporter activity
CY657_RS23090	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY657_RS23100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CY657_RS23110	COG0583	DNA-binding transcription factor activity
CY657_RS23130	COG0277	FAD linked oxidase domain protein
CY657_RS23135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS23160	COG0402	S-adenosylhomocysteine deaminase activity
CY657_RS23175	COG0583	DNA-binding transcription factor activity
CY657_RS23220	COG4608	Belongs to the ABC transporter superfamily
CY657_RS23225	COG0444	Belongs to the ABC transporter superfamily
CY657_RS23250	COG0346	lactoylglutathione lyase activity
CY657_RS23255	COG1349	DNA-binding transcription factor activity
CY657_RS23285	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CY657_RS23345	COG0307	riboflavin synthase, alpha
CY657_RS23350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CY657_RS23355	COG2814	Major facilitator Superfamily
CY657_RS23360	COG0583	DNA-binding transcription factor activity
CY657_RS23375	COG2814	Major facilitator Superfamily
CY657_RS23390	COG0791	NLP P60 protein
CY657_RS23395	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CY657_RS23405	COG0346	lactoylglutathione lyase activity
CY657_RS23410	COG1902	pentaerythritol trinitrate reductase activity
CY657_RS23415	COG1309	transcriptional regulator
CY657_RS23420	COG3313	Fe-S protein
CY657_RS23425	COG4989	oxidoreductase activity
CY657_RS23430	COG2032	superoxide dismutase activity
CY657_RS23435	COG1289	transmembrane transporter activity
CY657_RS23440	COG1566	PFAM secretion protein HlyD family protein
CY657_RS23455	COG3706	GGDEF domain
CY657_RS23470	COG3895	Periplasmic Protein
CY657_RS23485	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CY657_RS23490	COG0625	glutathione transferase activity
CY657_RS23505	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CY657_RS23515	COG4659	FMN binding
CY657_RS23550	COG2723	6-phospho-beta-galactosidase activity
CY657_RS23560	COG0673	inositol 2-dehydrogenase activity
CY657_RS23570	COG2814	Major facilitator Superfamily
CY657_RS23590	COG3038	cytochrome b561
CY657_RS23610	COG0583	DNA-binding transcription factor activity
CY657_RS23615	COG3485	protocatechuate 3,4-dioxygenase
CY657_RS23620	COG3485	protocatechuate 3,4-dioxygenase
CY657_RS23625	COG5383	Protein conserved in bacteria
CY657_RS23630	COG2272	Belongs to the type-B carboxylesterase lipase family
CY657_RS23645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY657_RS23650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CY657_RS23655	COG1275	C4-dicarboxylate transporter malic acid transport protein
CY657_RS23660	COG0500	methyltransferase
CY657_RS23675	COG3708	Transcriptional regulator
CY657_RS23675	COG2207	Transcriptional regulator
CY657_RS23680	COG3135	benzoate transporter
CY657_RS23685	COG1396	sequence-specific DNA binding
CY657_RS23695	COG0826	peptidase U32
CY657_RS23715	COG1294	oxidase, subunit
CY657_RS23720	COG1271	oxidase subunit
CY657_RS23725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY657_RS23730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CY657_RS23735	COG3842	ATPase activity
CY657_RS23740	COG1176	ABC-type spermidine putrescine transport system, permease component I
CY657_RS23745	COG1177	transmembrane transport
CY657_RS23750	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS23780	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS23785	COG0747	negative chemotaxis
CY657_RS23795	COG3238	Protein conserved in bacteria
CY657_RS23800	COG1247	-acetyltransferase
CY657_RS23810	COG2130	NADP-dependent
CY657_RS23825	COG3691	Protein conserved in bacteria
CY657_RS23830	COG1228	amidohydrolase
CY657_RS23835	COG4772	TonB-dependent receptor
CY657_RS23860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CY657_RS23865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS23870	COG1473	amidohydrolase
CY657_RS23875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS23880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS23890	COG0765	amino acid transport
CY657_RS23895	COG1126	abc transporter atp-binding protein
CY657_RS23905	COG2271	Major facilitator Superfamily
CY657_RS23915	COG1609	Transcriptional regulator
CY657_RS23920	COG0625	glutathione transferase activity
CY657_RS23935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CY657_RS23940	COG3842	ATPase activity
CY657_RS23945	COG1840	ABC-type Fe3 transport system, periplasmic component
CY657_RS23950	COG1178	ABC-type Fe3 transport system permease component
CY657_RS23955	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CY657_RS23960	COG2181	nitrate reductase activity
CY657_RS23965	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CY657_RS23970	COG1140	nitrate reductase beta subunit
CY657_RS23975	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CY657_RS23995	COG1414	Transcriptional regulator
CY657_RS24000	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS24005	COG4829	muconolactone delta-isomerase
CY657_RS24010	COG3485	protocatechuate 3,4-dioxygenase
CY657_RS24020	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CY657_RS24040	COG0243	molybdopterin cofactor binding
CY657_RS24040	COG3383	formate dehydrogenase (NAD+) activity
CY657_RS24045	COG3383	formate dehydrogenase (NAD+) activity
CY657_RS24045	COG0243	molybdopterin cofactor binding
CY657_RS24050	COG0437	4 iron, 4 sulfur cluster binding
CY657_RS24055	COG2864	formate dehydrogenase
CY657_RS24070	COG2326	polyphosphate kinase activity
CY657_RS24080	COG2814	Major facilitator Superfamily
CY657_RS24090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS24100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS24110	COG0747	negative chemotaxis
CY657_RS24115	COG1064	alcohol dehydrogenase
CY657_RS24130	COG0488	(ABC) transporter
CY657_RS24170	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS24175	COG3729	General stress protein
CY657_RS24195	COG3685	Protein conserved in bacteria
CY657_RS24205	COG0366	Alpha amylase catalytic
CY657_RS24215	COG2323	membrane
CY657_RS24225	COG3111	PFAM Bacterial OB fold (BOF) protein
CY657_RS24230	COG1764	response to oxidative stress
CY657_RS24255	COG3781	membrane
CY657_RS24260	COG0243	molybdopterin cofactor binding
CY657_RS24265	COG0583	DNA-binding transcription factor activity
CY657_RS24270	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS24275	COG2814	Major facilitator Superfamily
CY657_RS24285	COG1285	pathogenesis
CY657_RS24290	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CY657_RS24300	COG0583	DNA-binding transcription factor activity
CY657_RS24320	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CY657_RS24320	COG0519	Catalyzes the synthesis of GMP from XMP
CY657_RS24360	COG0596	Alpha beta hydrolase
CY657_RS24370	COG2205	protein histidine kinase activity
CY657_RS24385	COG0076	glutamate decarboxylase activity
CY657_RS24390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CY657_RS24395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY657_RS24400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS24405	COG1116	anion transmembrane transporter activity
CY657_RS24410	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CY657_RS24425	COG0673	inositol 2-dehydrogenase activity
CY657_RS24435	COG1609	Transcriptional regulator
CY657_RS24440	COG3706	GGDEF domain
CY657_RS24445	COG0402	S-adenosylhomocysteine deaminase activity
CY657_RS24450	COG1953	Uracil, thiamine, allantoin
CY657_RS24485	COG0596	Alpha beta hydrolase
CY657_RS24500	COG2207	Transcriptional regulator
CY657_RS24515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CY657_RS24580	COG0765	amino acid transport
CY657_RS24590	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CY657_RS24600	COG2070	2-Nitropropane dioxygenase
CY657_RS24605	COG0583	DNA-binding transcription factor activity
CY657_RS24615	COG1902	pentaerythritol trinitrate reductase activity
CY657_RS24620	COG4529	Protein conserved in bacteria
CY657_RS24625	COG0477	Major facilitator Superfamily
CY657_RS24665	COG2223	nitrite transmembrane transporter activity
CY657_RS24675	COG1609	Transcriptional regulator
CY657_RS24680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS24690	COG0583	DNA-binding transcription factor activity
CY657_RS24695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY657_RS24720	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS24730	COG1609	Transcriptional regulator
CY657_RS24760	COG1652	LysM domain
CY657_RS24790	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CY657_RS24790	COG0456	acetyltransferase
CY657_RS24800	COG0667	Aldo Keto reductase
CY657_RS24805	COG0667	Aldo Keto reductase
CY657_RS24810	COG3386	PFAM SMP-30 Gluconolaconase
CY657_RS24815	COG0667	Aldo Keto reductase
CY657_RS24840	COG4977	sequence-specific DNA binding
CY657_RS24865	COG1349	DNA-binding transcription factor activity
CY657_RS24870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CY657_RS24875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS24880	COG0738	Major facilitator superfamily
CY657_RS24925	COG1929	Belongs to the glycerate kinase type-1 family
CY657_RS24930	COG3835	regulator
CY657_RS24950	COG2186	Transcriptional regulator
CY657_RS24955	COG1263	PTS System
CY657_RS24955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS24965	COG2814	Major facilitator Superfamily
CY657_RS24970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS24970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS24980	COG2819	hydrolase of the alpha beta superfamily
CY657_RS24985	COG3300	MHYT domain
CY657_RS24985	COG5001	Diguanylate cyclase
CY657_RS25020	COG3188	usher protein
CY657_RS25030	COG1649	PFAM Uncharacterised BCR, COG1649
CY657_RS25035	COG3550	peptidyl-serine autophosphorylation
CY657_RS25040	COG1396	sequence-specific DNA binding
CY657_RS25045	COG2351	hydroxyisourate hydrolase activity
CY657_RS25050	COG3648	Uricase
CY657_RS25050	COG3195	allantoin biosynthetic process
CY657_RS25055	COG2233	PERMEase
CY657_RS25085	COG2207	Transcriptional regulator
CY657_RS25100	COG4628	conserved protein (DUF2132)
CY657_RS25120	COG2011	ABC-type metal ion transport system permease component
CY657_RS25125	COG2070	2-Nitropropane dioxygenase
CY657_RS25135	COG0477	Major facilitator Superfamily
CY657_RS25215	COG2199	diguanylate cyclase activity
CY657_RS25230	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS25235	COG0583	DNA-binding transcription factor activity
CY657_RS25245	COG0039	L-malate dehydrogenase activity
CY657_RS25250	COG1349	DNA-binding transcription factor activity
CY657_RS25255	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CY657_RS25260	COG3395	kinase activity
CY657_RS25270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CY657_RS25275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY657_RS25280	COG2271	Major facilitator Superfamily
CY657_RS25305	COG4977	sequence-specific DNA binding
CY657_RS25315	COG0697	spore germination
CY657_RS25320	COG2814	Major facilitator Superfamily
CY657_RS25350	COG0683	leucine binding
CY657_RS25355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CY657_RS25390	COG2223	nitrite transmembrane transporter activity
CY657_RS25395	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CY657_RS25410	COG1349	DNA-binding transcription factor activity
CY657_RS25415	COG2084	Dehydrogenase
CY657_RS25420	COG3395	kinase activity
CY657_RS25425	COG0235	Class ii aldolase
CY657_RS25430	COG3622	Belongs to the hyi family
CY657_RS25435	COG2610	gluconate transmembrane transporter activity
CY657_RS25440	COG2207	Transcriptional regulator
CY657_RS25440	COG3708	Transcriptional regulator
CY657_RS25455	COG2200	EAL domain
CY657_RS25460	COG1546	Belongs to the CinA family
CY657_RS25465	COG0071	Belongs to the small heat shock protein (HSP20) family
CY657_RS25485	COG2135	peptidase activity
CY657_RS25490	COG2207	Transcriptional regulator
CY657_RS25505	COG4221	oxidoreductase activity
CY657_RS25510	COG1802	Transcriptional regulator
CY657_RS25515	COG0589	response to stress
CY657_RS25520	COG0246	Mannitol dehydrogenase
CY657_RS25525	COG2271	Major facilitator Superfamily
CY657_RS25540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY657_RS25555	COG0243	molybdopterin cofactor binding
CY657_RS25560	COG0437	4 iron, 4 sulfur cluster binding
CY657_RS25565	COG3302	dmso reductase anchor subunit
CY657_RS25580	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CY657_RS25585	COG1940	carbohydrate kinase activity
CY657_RS25590	COG0583	DNA-binding transcription factor activity
CY657_RS25595	COG2814	Major facilitator Superfamily
CY657_RS25600	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CY657_RS25610	COG3591	Belongs to the peptidase S1B family
CY657_RS25630	COG0628	permease
CY657_RS25660	COG0679	Auxin Efflux Carrier
CY657_RS25670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CY657_RS25695	COG3290	protein histidine kinase activity
CY657_RS25700	COG4565	transcriptional regulatory protein
CY657_RS25725	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CY657_RS25725	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CY657_RS25745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS25750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CY657_RS25760	COG0183	Belongs to the thiolase family
CY657_RS25765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CY657_RS25775	COG1414	Transcriptional regulator
CY657_RS25780	COG2840	Smr protein MutS2
CY657_RS25785	COG0583	DNA-binding transcription factor activity
CY657_RS25795	COG1473	amidohydrolase
CY657_RS25800	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CY657_RS25815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CY657_RS25830	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CY657_RS25835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CY657_RS25855	COG0531	amino acid
CY657_RS25865	COG3136	membrane protein required for alginate biosynthesis
CY657_RS25870	COG0745	RESPONSE REGULATOR receiver
CY657_RS25880	COG2205	protein histidine kinase activity
CY657_RS25890	COG0114	fumarate hydratase activity
CY657_RS25895	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CY657_RS25895	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CY657_RS25900	COG1482	cell wall glycoprotein biosynthetic process
CY657_RS25905	COG5339	Protein conserved in bacteria
CY657_RS25910	COG1609	Transcriptional regulator
CY657_RS25915	COG1263	PTS System
CY657_RS25915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS25920	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CY657_RS25945	COG2391	methyltransferase activity
CY657_RS25950	COG0425	Belongs to the sulfur carrier protein TusA family
CY657_RS25955	COG5562	phage envelope protein
CY657_RS25960	COG0401	homolog of Blt101
CY657_RS25965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CY657_RS25970	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS25975	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CY657_RS25980	COG0477	Major facilitator Superfamily
CY657_RS25985	COG1113	amino acid transport
CY657_RS25990	COG2988	succinylglutamate desuccinylase activity
CY657_RS25995	COG3724	N-succinylarginine dihydrolase activity
CY657_RS26000	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS26005	COG3138	arginine N-succinyltransferase
CY657_RS26010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CY657_RS26015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CY657_RS26020	COG0667	Aldo Keto reductase
CY657_RS26025	COG0583	DNA-binding transcription factor activity
CY657_RS26050	COG4122	O-methyltransferase activity
CY657_RS26055	COG1643	Atp-dependent helicase
CY657_RS26070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CY657_RS26075	COG3327	negative regulation of DNA-templated transcription, initiation
CY657_RS26080	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CY657_RS26085	COG0183	Belongs to the thiolase family
CY657_RS26090	COG2050	protein possibly involved in aromatic compounds catabolism
CY657_RS26095	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY657_RS26100	COG1024	Enoyl-CoA hydratase
CY657_RS26105	COG1024	Enoyl-CoA hydratase
CY657_RS26110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS26115	COG2151	metal-sulfur cluster biosynthetic enzyme
CY657_RS26120	COG3396	Phenylacetate-CoA oxygenase
CY657_RS26125	COG3460	Phenylacetate-CoA oxygenase
CY657_RS26130	COG3396	Phenylacetate-CoA oxygenase
CY657_RS26135	COG2030	dehydratase
CY657_RS26135	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS26165	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS26170	COG2207	Transcriptional regulator
CY657_RS26175	COG3784	Protein of unknown function (DUF1318)
CY657_RS26185	COG2911	Protein conserved in bacteria
CY657_RS26190	COG0586	Pfam SNARE associated Golgi protein
CY657_RS26195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CY657_RS26200	COG3187	Heat shock protein
CY657_RS26205	COG3042	response to heat
CY657_RS26215	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY657_RS26215	COG0674	pyruvate-flavodoxin oxidoreductase activity
CY657_RS26215	COG1013	pyruvate-flavodoxin oxidoreductase activity
CY657_RS26215	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CY657_RS26220	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CY657_RS26230	COG0589	response to stress
CY657_RS26240	COG0513	Belongs to the DEAD box helicase family
CY657_RS26260	COG1349	DNA-binding transcription factor activity
CY657_RS26265	COG0673	inositol 2-dehydrogenase activity
CY657_RS26280	COG2011	ABC-type metal ion transport system permease component
CY657_RS26295	COG0436	Aminotransferase
CY657_RS26300	COG0604	alcohol dehydrogenase
CY657_RS26325	COG0583	DNA-binding transcription factor activity
CY657_RS26345	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS26350	COG1309	transcriptional regulator
CY657_RS26355	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS26455	COG2885	chlorophyll binding
CY657_RS26480	COG0693	protein deglycase activity
CY657_RS26485	COG1078	dGTPase activity
CY657_RS26490	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS26495	COG0583	DNA-binding transcription factor activity
CY657_RS26515	COG0656	L-ascorbic acid biosynthetic process
CY657_RS26545	COG4166	transmembrane transport
CY657_RS26550	COG2866	Carboxypeptidase
CY657_RS26555	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS26560	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CY657_RS26565	COG3180	Ammonia monooxygenase
CY657_RS26575	COG1486	melibiose metabolic process
CY657_RS26580	COG0583	DNA-binding transcription factor activity
CY657_RS26590	COG3106	COG3106 Predicted ATPase
CY657_RS26600	COG1983	PspC domain protein
CY657_RS26610	COG1842	Phage shock protein A
CY657_RS26615	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CY657_RS26625	COG1473	amidohydrolase
CY657_RS26640	COG0702	epimerase
CY657_RS26655	COG2135	peptidase activity
CY657_RS26665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CY657_RS26670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair