locus-tag	class	description
CY657_RS00030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CY657_RS00035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CY657_RS00095	COG1196	nuclear chromosome segregation
CY657_RS00180	COG5484	DNA packaging
CY657_RS00180	COG3728	DNA packaging
CY657_RS00235	COG0484	heat shock protein binding
CY657_RS00240	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CY657_RS00295	COG1484	DNA-dependent DNA replication
CY657_RS00335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY657_RS00370	COG4171	peptide transport system, permease
CY657_RS00385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CY657_RS00395	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CY657_RS00400	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS00400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS00415	COG1349	DNA-binding transcription factor activity
CY657_RS00425	COG0023	Translation Initiation Factor
CY657_RS00435	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CY657_RS00440	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CY657_RS00445	COG0671	phosphoesterase, PA-phosphatase related
CY657_RS00455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CY657_RS00480	COG0616	signal peptide processing
CY657_RS00490	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS00495	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CY657_RS00505	COG0583	DNA-binding transcription factor activity
CY657_RS00515	COG0009	L-threonylcarbamoyladenylate synthase
CY657_RS00525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CY657_RS00530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CY657_RS00530	COG0512	Glutamine amidotransferase of anthranilate synthase
CY657_RS00535	COG0134	indole-3-glycerol-phosphate synthase activity
CY657_RS00535	COG0135	phosphoribosylanthranilate isomerase activity
CY657_RS00570	COG4774	siderophore transport
CY657_RS00580	COG3047	cAMP biosynthetic process
CY657_RS00585	COG0727	PFAM Uncharacterised protein family (UPF0153)
CY657_RS00615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS00620	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS00625	COG1988	membrane-bound metal-dependent
CY657_RS00630	COG1823	symporter activity
CY657_RS00640	COG0753	catalase activity
CY657_RS00650	COG1486	melibiose metabolic process
CY657_RS00655	COG1917	Cupin 2, conserved barrel domain protein
CY657_RS00655	COG2169	Transcriptional regulator
CY657_RS00660	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS00665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS00670	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS00675	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CY657_RS00685	COG0322	excinuclease ABC activity
CY657_RS00690	COG3678	ATP-independent chaperone mediated protein folding
CY657_RS00700	COG3724	N-succinylarginine dihydrolase activity
CY657_RS00710	COG3138	arginine N-succinyltransferase
CY657_RS00720	COG0708	Exodeoxyribonuclease III
CY657_RS00725	COG0398	Pfam SNARE associated Golgi protein
CY657_RS00730	COG0398	Pfam SNARE associated Golgi protein
CY657_RS00735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS00740	COG4134	Bacterial extracellular solute-binding protein
CY657_RS00745	COG4135	transport system, permease component
CY657_RS00750	COG4136	ATPase activity
CY657_RS00755	COG2897	thiosulfate sulfurtransferase activity
CY657_RS00760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CY657_RS00765	COG0494	nUDIX hydrolase
CY657_RS00770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CY657_RS00775	COG0604	alcohol dehydrogenase
CY657_RS00775	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS00775	COG3321	synthase
CY657_RS00780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CY657_RS00785	COG0709	Synthesizes selenophosphate from selenide and ATP
CY657_RS00800	COG0778	Nitroreductase
CY657_RS00805	COG0616	signal peptide processing
CY657_RS00810	COG0252	asparaginase activity
CY657_RS00815	COG1335	isochorismatase
CY657_RS00830	COG3139	Protein of unknown function (DUF1315)
CY657_RS00850	COG0656	L-ascorbic acid biosynthetic process
CY657_RS00855	COG3713	MltA-interacting MipA family protein
CY657_RS00860	COG2766	serine protein kinase
CY657_RS00875	COG0386	Belongs to the glutathione peroxidase family
CY657_RS00895	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS00900	COG0583	DNA-binding transcription factor activity
CY657_RS00905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CY657_RS00910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CY657_RS00920	COG0859	PFAM glycosyl transferase family 9
CY657_RS00925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CY657_RS00935	COG2207	Transcriptional regulator
CY657_RS00940	COG2807	transmembrane transport
CY657_RS00945	COG0504	CTP synthase activity
CY657_RS00950	COG1683	Conserved Protein
CY657_RS00955	COG3189	MarR family transcriptional regulator
CY657_RS00960	COG3042	response to heat
CY657_RS00965	COG2203	Gaf domain
CY657_RS00965	COG2199	diguanylate cyclase activity
CY657_RS00985	COG3182	Iron-regulated membrane protein
CY657_RS00995	COG1560	Kdo2-lipid A biosynthetic process
CY657_RS01005	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CY657_RS01010	COG3706	GGDEF domain
CY657_RS01015	COG0583	DNA-binding transcription factor activity
CY657_RS01020	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CY657_RS01045	COG1294	oxidase, subunit
CY657_RS01050	COG1271	oxidase subunit
CY657_RS01060	COG3685	Protein conserved in bacteria
CY657_RS01065	COG3685	Protein conserved in bacteria
CY657_RS01070	COG3729	General stress protein
CY657_RS01075	COG1063	alcohol dehydrogenase
CY657_RS01080	COG3813	Protein conserved in bacteria
CY657_RS01105	COG0640	Transcriptional regulator
CY657_RS01110	COG0538	isocitrate dehydrogenase activity
CY657_RS01120	COG5001	Diguanylate cyclase
CY657_RS01120	COG3300	MHYT domain
CY657_RS01125	COG3706	GGDEF domain
CY657_RS01140	COG0582	viral genome integration into host DNA
CY657_RS01145	COG0538	isocitrate dehydrogenase activity
CY657_RS01150	COG1187	pseudouridine synthase activity
CY657_RS01170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CY657_RS01190	COG2205	protein histidine kinase activity
CY657_RS01195	COG2850	peptidyl-arginine hydroxylation
CY657_RS01200	COG1943	Transposase
CY657_RS01225	COG1177	transmembrane transport
CY657_RS01240	COG0318	PFAM AMP-dependent synthetase and ligase
CY657_RS01245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CY657_RS01250	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CY657_RS01255	COG0698	ribose 5-phosphate isomerase
CY657_RS01270	COG3395	kinase activity
CY657_RS01285	COG2390	Transcriptional regulator
CY657_RS01295	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CY657_RS01305	COG4591	ABC-type transport system involved in lipoprotein release permease component
CY657_RS01315	COG4591	ABC-type transport system involved in lipoprotein release permease component
CY657_RS01320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CY657_RS01325	COG1388	LysM domain
CY657_RS01325	COG1376	ErfK ybiS ycfS ynhG family protein
CY657_RS01335	COG1309	transcriptional regulator
CY657_RS01345	COG3134	Outer membrane lipoprotein
CY657_RS01350	COG1252	NADH dehydrogenase
CY657_RS01375	COG5633	Lipoprotein
CY657_RS01380	COG0537	adenosine 5'-monophosphoramidase activity
CY657_RS01390	COG0084	hydrolase, TatD family'
CY657_RS01395	COG0470	DNA polymerase III
CY657_RS01405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CY657_RS01410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CY657_RS01415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CY657_RS01430	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CY657_RS01450	COG1399	metal-binding, possibly nucleic acid-binding protein
CY657_RS01465	COG1530	ribonuclease E activity
CY657_RS01470	COG0583	DNA-binding transcription factor activity
CY657_RS01475	COG2814	Major facilitator Superfamily
CY657_RS01495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY657_RS01545	COG1560	Kdo2-lipid A biosynthetic process
CY657_RS01560	COG5645	(Lipo)protein
CY657_RS01595	COG3381	protein complex oligomerization
CY657_RS01635	COG1309	transcriptional regulator
CY657_RS01640	COG0583	DNA-binding transcription factor activity
CY657_RS01650	COG1335	isochorismatase
CY657_RS01660	COG1702	phosphate starvation-inducible protein PhoH
CY657_RS01680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY657_RS01690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CY657_RS01705	COG1309	transcriptional regulator
CY657_RS01740	COG2233	PERMEase
CY657_RS01750	COG3729	General stress protein
CY657_RS01775	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS01790	COG0531	amino acid
CY657_RS01800	COG0174	glutamine synthetase
CY657_RS01805	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CY657_RS01810	COG1396	sequence-specific DNA binding
CY657_RS01810	COG1917	Cupin 2, conserved barrel domain protein
CY657_RS01815	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS01820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY657_RS01830	COG0473	3-isopropylmalate dehydrogenase activity
CY657_RS01835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CY657_RS01840	COG4638	Rieske (2fe-2S)
CY657_RS01845	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS01850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS01860	COG2200	EAL domain
CY657_RS01865	COG2200	EAL domain
CY657_RS01880	COG0670	Belongs to the BI1 family
CY657_RS01895	COG2207	Transcriptional regulator
CY657_RS01900	COG1881	PFAM PEBP family protein
CY657_RS01915	COG1832	CoA-binding protein
CY657_RS01925	COG0210	DNA helicase
CY657_RS01930	COG3304	Inner membrane component domain
CY657_RS01935	COG1289	transmembrane transporter activity
CY657_RS01940	COG3070	regulator of competence-specific genes
CY657_RS01965	COG1067	ATP-dependent peptidase activity
CY657_RS01975	COG3130	regulation of translation
CY657_RS01980	COG3009	Protein conserved in bacteria
CY657_RS01985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CY657_RS01985	COG3008	intermembrane lipid transfer
CY657_RS01990	COG2995	paraquat-inducible protein a
CY657_RS01995	COG0488	(ABC) transporter
CY657_RS02005	COG0633	Ferredoxin
CY657_RS02005	COG3217	Mosc domain protein beta barrel domain protein
CY657_RS02020	COG0431	NADPH-dependent FMN reductase
CY657_RS02025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY657_RS02030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS02035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS02045	COG0308	aminopeptidase N
CY657_RS02055	COG1473	amidohydrolase
CY657_RS02065	COG0814	amino acid
CY657_RS02075	COG1522	sequence-specific DNA binding
CY657_RS02085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CY657_RS02090	COG1448	Aminotransferase
CY657_RS02095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY657_RS02100	COG3108	Peptidase M15
CY657_RS02105	COG2989	Protein conserved in bacteria
CY657_RS02115	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CY657_RS02125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CY657_RS02130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CY657_RS02135	COG3173	Aminoglycoside phosphotransferase
CY657_RS02150	COG3214	Protein conserved in bacteria
CY657_RS02165	COG0658	competence protein
CY657_RS02165	COG2333	competence protein COMEC
CY657_RS02175	COG0539	negative regulation of cytoplasmic translation
CY657_RS02195	COG2323	membrane
CY657_RS02200	COG1944	ATP diphosphatase activity
CY657_RS02205	COG2116	formate transmembrane transporter activity
CY657_RS02210	COG1882	Formate acetyltransferase
CY657_RS02215	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CY657_RS02220	COG0477	Major facilitator Superfamily
CY657_RS02230	COG3302	dmso reductase anchor subunit
CY657_RS02235	COG0437	4 iron, 4 sulfur cluster binding
CY657_RS02240	COG0243	molybdopterin cofactor binding
CY657_RS02250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CY657_RS02260	COG1674	ftsk spoiiie
CY657_RS02260	COG1178	ABC-type Fe3 transport system permease component
CY657_RS02270	COG0492	ferredoxin-NADP+ reductase activity
CY657_RS02275	COG4988	ABC transporter
CY657_RS02280	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CY657_RS02295	COG0542	response to heat
CY657_RS02305	COG1278	Cold shock
CY657_RS02315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS02320	COG3593	DNA synthesis involved in DNA repair
CY657_RS02330	COG2431	L-lysine efflux transmembrane transporter activity
CY657_RS02340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS02350	COG0028	Belongs to the TPP enzyme family
CY657_RS02355	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CY657_RS02360	COG0702	epimerase
CY657_RS02365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY657_RS02370	COG3023	N-Acetylmuramoyl-L-alanine amidase
CY657_RS02375	COG2203	Gaf domain
CY657_RS02375	COG4251	negative regulation of phosphorylation
CY657_RS02375	COG5001	Diguanylate cyclase
CY657_RS02375	COG3706	GGDEF domain
CY657_RS02385	COG1126	abc transporter atp-binding protein
CY657_RS02390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS02395	COG4215	(ABC) transporter
CY657_RS02400	COG4160	amino acid transport
CY657_RS02405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS02410	COG5002	protein histidine kinase activity
CY657_RS02415	COG0745	RESPONSE REGULATOR receiver
CY657_RS02430	COG1177	transmembrane transport
CY657_RS02435	COG1176	ABC-type spermidine putrescine transport system, permease component I
CY657_RS02440	COG3842	ATPase activity
CY657_RS02445	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CY657_RS02460	COG0778	Nitroreductase
CY657_RS02485	COG3226	Transcriptional regulator
CY657_RS02490	COG0738	Major facilitator superfamily
CY657_RS02495	COG0561	phosphatase activity
CY657_RS02500	COG2814	Major facilitator Superfamily
CY657_RS02510	COG0671	phosphoesterase, PA-phosphatase related
CY657_RS02515	COG1349	DNA-binding transcription factor activity
CY657_RS02520	COG1686	Belongs to the peptidase S11 family
CY657_RS02525	COG0625	glutathione transferase activity
CY657_RS02530	COG2133	pyrroloquinoline quinone binding
CY657_RS02540	COG2223	nitrite transmembrane transporter activity
CY657_RS02560	COG0747	negative chemotaxis
CY657_RS02575	COG0303	'Molybdopterin
CY657_RS02580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CY657_RS02585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CY657_RS02590	COG1882	Formate acetyltransferase
CY657_RS02595	COG0561	phosphatase activity
CY657_RS02605	COG1609	Transcriptional regulator
CY657_RS02610	COG2271	Major facilitator Superfamily
CY657_RS02620	COG0488	(ABC) transporter
CY657_RS02625	COG2365	Tyrosine phosphatase family
CY657_RS02630	COG1376	ErfK ybiS ycfS ynhG family protein
CY657_RS02635	COG2188	Transcriptional regulator
CY657_RS02640	COG2723	6-phospho-beta-galactosidase activity
CY657_RS02645	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CY657_RS02660	COG2194	sulfuric ester hydrolase activity
CY657_RS02665	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CY657_RS02680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS02685	COG0765	amino acid transport
CY657_RS02690	COG1126	abc transporter atp-binding protein
CY657_RS02695	COG0668	transmembrane transport
CY657_RS02705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CY657_RS02715	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CY657_RS02725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CY657_RS02730	COG1199	ATP-dependent helicase activity
CY657_RS02735	COG0513	Belongs to the DEAD box helicase family
CY657_RS02740	COG3958	Transketolase
CY657_RS02745	COG3959	Transketolase, thiamine diphosphate binding domain
CY657_RS02750	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS02755	COG2271	Major facilitator Superfamily
CY657_RS02760	COG0583	DNA-binding transcription factor activity
CY657_RS02765	COG1309	transcriptional regulator
CY657_RS02770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS02775	COG1131	(ABC) transporter
CY657_RS02780	COG0842	Transport permease protein
CY657_RS02785	COG0842	Transport permease protein
CY657_RS02795	COG3568	Endonuclease Exonuclease Phosphatase
CY657_RS02800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY657_RS02805	COG0392	lysyltransferase activity
CY657_RS02815	COG0670	Belongs to the BI1 family
CY657_RS02820	COG0314	molybdopterin synthase activity
CY657_RS02825	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CY657_RS02835	COG0521	Mo-molybdopterin cofactor biosynthetic process
CY657_RS02860	COG0745	RESPONSE REGULATOR receiver
CY657_RS02865	COG0642	Histidine kinase
CY657_RS02900	COG2226	methyltransferase
CY657_RS02915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY657_RS02920	COG1881	PFAM PEBP family protein
CY657_RS02955	COG4677	pectinesterase activity
CY657_RS02970	COG0589	response to stress
CY657_RS02975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS03005	COG0789	Transcriptional regulator
CY657_RS03010	COG2200	EAL domain
CY657_RS03035	COG0561	phosphatase activity
CY657_RS03045	COG4149	molybdate abc transporter
CY657_RS03050	COG0725	ABC transporter, periplasmic molybdate-binding protein
CY657_RS03060	COG2005	Transcriptional regulator
CY657_RS03060	COG3585	molybdate ion transport
CY657_RS03065	COG1119	ATPase activity
CY657_RS03075	COG1085	galactose-1-phosphate uridylyltransferase
CY657_RS03085	COG2017	converts alpha-aldose to the beta-anomer
CY657_RS03095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CY657_RS03110	COG3201	nicotinamide mononucleotide transporter
CY657_RS03115	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CY657_RS03160	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CY657_RS03165	COG2885	chlorophyll binding
CY657_RS03175	COG3064	Membrane
CY657_RS03180	COG0848	biopolymer transport protein
CY657_RS03185	COG0811	peptide transport
CY657_RS03190	COG0824	Thioesterase
CY657_RS03195	COG3790	cyd operon protein YbgE
CY657_RS03200	COG4890	Cyd operon protein YbgT
CY657_RS03205	COG1294	oxidase, subunit
CY657_RS03210	COG1271	oxidase subunit
CY657_RS03220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CY657_RS03230	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY657_RS03235	COG0567	Dehydrogenase, E1 component
CY657_RS03240	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CY657_RS03245	COG1053	succinate dehydrogenase
CY657_RS03250	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CY657_RS03255	COG2009	succinate dehydrogenase
CY657_RS03290	COG1984	allophanate hydrolase subunit 2
CY657_RS03295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CY657_RS03310	COG0415	Belongs to the DNA photolyase family
CY657_RS03340	COG2205	protein histidine kinase activity
CY657_RS03345	COG0745	RESPONSE REGULATOR receiver
CY657_RS03355	COG0033	Phosphoglucomutase
CY657_RS03365	COG0596	Alpha beta hydrolase
CY657_RS03380	COG0735	belongs to the Fur family
CY657_RS03420	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CY657_RS03425	COG1940	carbohydrate kinase activity
CY657_RS03425	COG1846	Transcriptional regulator
CY657_RS03430	COG0647	UMP catabolic process
CY657_RS03435	COG0367	asparagine synthase
CY657_RS03480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CY657_RS03490	COG1702	phosphate starvation-inducible protein PhoH
CY657_RS03515	COG0765	amino acid transport
CY657_RS03520	COG0765	amino acid transport
CY657_RS03525	COG1126	abc transporter atp-binding protein
CY657_RS03540	COG2888	peptidyl-tyrosine sulfation
CY657_RS03555	COG1466	dna polymerase III delta subunit
CY657_RS03570	COG0799	negative regulation of ribosome biogenesis
CY657_RS03580	COG0768	penicillin binding
CY657_RS03585	COG0772	Belongs to the SEDS family
CY657_RS03590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CY657_RS03595	COG1686	Belongs to the peptidase S11 family
CY657_RS03610	COG0583	DNA-binding transcription factor activity
CY657_RS03625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CY657_RS03645	COG3069	C4-dicarboxylate transmembrane transporter activity
CY657_RS03650	COG3719	Belongs to the RNase T2 family
CY657_RS03655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CY657_RS03675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CY657_RS03680	COG0583	DNA-binding transcription factor activity
CY657_RS03685	COG3969	phosphoadenosine phosphosulfate
CY657_RS03690	COG1475	DNA binding
CY657_RS03695	COG0436	Aminotransferase
CY657_RS03720	COG1129	ABC transporter
CY657_RS03725	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS03730	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS03740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY657_RS03755	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CY657_RS03765	COG0402	S-adenosylhomocysteine deaminase activity
CY657_RS03775	COG0483	inositol monophosphate 1-phosphatase activity
CY657_RS03780	COG2271	Major facilitator Superfamily
CY657_RS03810	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS03815	COG1129	ABC transporter
CY657_RS03820	COG0371	Dehydrogenase
CY657_RS03825	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS03840	COG2879	small protein
CY657_RS03845	COG1966	Carbon starvation protein
CY657_RS03855	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS03860	COG3433	isochorismatase activity
CY657_RS03860	COG1535	isochorismatase
CY657_RS03865	COG1021	2,3-dihydroxybenzoate-AMP ligase
CY657_RS03870	COG1169	isochorismate synthase
CY657_RS03875	COG4592	Periplasmic binding protein
CY657_RS03885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS03890	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS03895	COG1120	ATPase activity
CY657_RS03900	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CY657_RS03900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CY657_RS03905	COG3251	PFAM MbtH domain protein
CY657_RS03910	COG2382	esterase
CY657_RS03915	COG4771	TonB-dependent receptor
CY657_RS03920	COG2977	Belongs to the P-Pant transferase superfamily
CY657_RS03925	COG3958	Transketolase
CY657_RS03930	COG3959	Transketolase, thiamine diphosphate binding domain
CY657_RS03935	COG2390	Transcriptional regulator
CY657_RS03940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CY657_RS03945	COG1879	ABC-type sugar transport system periplasmic component
CY657_RS03955	COG1129	ABC transporter
CY657_RS03960	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS03970	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS03980	COG0583	DNA-binding transcription factor activity
CY657_RS03985	COG0668	transmembrane transport
CY657_RS03995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CY657_RS04020	COG0747	negative chemotaxis
CY657_RS04025	COG0601	transmembrane transport
CY657_RS04030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS04035	COG0444	Belongs to the ABC transporter superfamily
CY657_RS04040	COG4608	Belongs to the ABC transporter superfamily
CY657_RS04045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY657_RS04050	COG4221	oxidoreductase activity
CY657_RS04060	COG4215	(ABC) transporter
CY657_RS04070	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CY657_RS04085	COG0697	spore germination
CY657_RS04100	COG4608	Belongs to the ABC transporter superfamily
CY657_RS04105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS04115	COG4166	transmembrane transport
CY657_RS04125	COG3698	Phosphodiester glycosidase
CY657_RS04170	COG2315	Protein conserved in bacteria
CY657_RS04175	COG0778	Nitroreductase
CY657_RS04185	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS04195	COG3716	PTS system mannose fructose sorbose family IID component
CY657_RS04200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CY657_RS04205	COG2222	sugar isomerase
CY657_RS04210	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CY657_RS04210	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CY657_RS04225	COG0477	Major facilitator Superfamily
CY657_RS04230	COG0668	transmembrane transport
CY657_RS04235	COG1609	Transcriptional regulator
CY657_RS04245	COG0673	inositol 2-dehydrogenase activity
CY657_RS04255	COG2211	Major facilitator Superfamily
CY657_RS04260	COG1113	amino acid transport
CY657_RS04275	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS04280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY657_RS04290	COG0531	amino acid
CY657_RS04335	COG0667	Aldo Keto reductase
CY657_RS04340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS04345	COG1473	amidohydrolase
CY657_RS04365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS04370	COG1120	ATPase activity
CY657_RS04375	COG1566	PFAM secretion protein HlyD family protein
CY657_RS04420	COG4211	Belongs to the binding-protein-dependent transport system permease family
CY657_RS04425	COG1129	ABC transporter
CY657_RS04470	COG3104	oligopeptide transport
CY657_RS04475	COG1982	Orn Lys Arg decarboxylase major
CY657_RS04480	COG0531	amino acid
CY657_RS04485	COG3710	Transcriptional regulator
CY657_RS04500	COG1560	Kdo2-lipid A biosynthetic process
CY657_RS04515	COG3188	usher protein
CY657_RS04520	COG3121	Chaperone
CY657_RS04525	COG3539	Fimbrial protein
CY657_RS04540	COG0372	Belongs to the citrate synthase family
CY657_RS04770	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CY657_RS04930	COG0582	viral genome integration into host DNA
CY657_RS04950	COG2501	S4 domain
CY657_RS04960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CY657_RS04975	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CY657_RS04980	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CY657_RS04995	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CY657_RS05000	COG4181	ATPase activity
CY657_RS05005	COG2755	lipolytic protein G-D-S-L family
CY657_RS05010	COG0300	oxidoreductase activity
CY657_RS05015	COG3118	belongs to the thioredoxin family
CY657_RS05025	COG0390	transport system, permease component
CY657_RS05030	COG4619	ABC transporter
CY657_RS05035	COG0330	HflC and HflK could
CY657_RS05040	COG1585	Membrane protein implicated in regulation of membrane protease activity
CY657_RS05055	COG3735	TraB family
CY657_RS05060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CY657_RS05070	COG2223	nitrite transmembrane transporter activity
CY657_RS05075	COG4651	solute:proton antiporter activity
CY657_RS05075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CY657_RS05080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS05120	COG2832	Protein of unknown function (DUF454)
CY657_RS05125	COG3923	Primosomal replication protein n
CY657_RS05140	COG3264	Mechanosensitive ion channel
CY657_RS05140	COG1196	nuclear chromosome segregation
CY657_RS05145	COG1309	transcriptional regulator
CY657_RS05150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS05155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS05170	COG0110	maltose O-acetyltransferase activity
CY657_RS05215	COG1874	Beta-galactosidase
CY657_RS05220	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CY657_RS05225	COG3833	ABC-type maltose transport systems, permease component
CY657_RS05230	COG1175	transmembrane transport
CY657_RS05235	COG2182	Extracellular solute-binding protein
CY657_RS05245	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CY657_RS05260	COG2364	Membrane
CY657_RS05290	COG3695	enzyme binding
CY657_RS05295	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CY657_RS05300	COG1946	Acyl-CoA thioesterase
CY657_RS05305	COG0004	ammonium transporteR
CY657_RS05310	COG0347	Belongs to the P(II) protein family
CY657_RS05315	COG1132	(ABC) transporter
CY657_RS05320	COG1132	(ABC) transporter
CY657_RS05325	COG1522	sequence-specific DNA binding
CY657_RS05340	COG4533	DNA binding
CY657_RS05350	COG0824	Thioesterase
CY657_RS05355	COG1555	photosystem II stabilization
CY657_RS05360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CY657_RS05365	COG0776	regulation of translation
CY657_RS05370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CY657_RS05400	COG0271	Belongs to the BolA IbaG family
CY657_RS05405	COG3056	Lipoprotein
CY657_RS05410	COG2223	nitrite transmembrane transporter activity
CY657_RS05415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CY657_RS05420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CY657_RS05425	COG1845	cytochrome c oxidase, subunit III
CY657_RS05430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CY657_RS05445	COG1414	Transcriptional regulator
CY657_RS05450	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CY657_RS05455	COG1053	succinate dehydrogenase
CY657_RS05465	COG1053	succinate dehydrogenase
CY657_RS05480	COG0673	inositol 2-dehydrogenase activity
CY657_RS05485	COG2814	Major facilitator Superfamily
CY657_RS05495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CY657_RS05500	COG0693	protein deglycase activity
CY657_RS05520	COG0142	geranyltranstransferase activity
CY657_RS05530	COG0667	Aldo Keto reductase
CY657_RS05535	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CY657_RS05555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CY657_RS05555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CY657_RS05565	COG4238	major outer membrane lipoprotein
CY657_RS05585	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CY657_RS05590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CY657_RS05595	COG1862	Preprotein translocase
CY657_RS05615	COG0450	alkyl hydroperoxide reductase
CY657_RS05620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS05635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS05645	COG1228	amidohydrolase
CY657_RS05655	COG1335	isochorismatase
CY657_RS05660	COG0583	DNA-binding transcription factor activity
CY657_RS05665	COG0366	Alpha amylase catalytic
CY657_RS05690	COG0420	3'-5' exonuclease activity
CY657_RS05695	COG0419	ATPase involved in DNA repair
CY657_RS05700	COG1940	carbohydrate kinase activity
CY657_RS05715	COG4126	flavin adenine dinucleotide binding
CY657_RS05725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CY657_RS05730	COG3416	Protein conserved in bacteria
CY657_RS05740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CY657_RS05750	COG1785	Belongs to the alkaline phosphatase family
CY657_RS05790	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CY657_RS05795	COG1335	isochorismatase
CY657_RS05800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CY657_RS05805	COG0113	porphobilinogen synthase activity
CY657_RS05815	COG2175	clavaminate synthase activity
CY657_RS05820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS05825	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CY657_RS05830	COG4521	taurine ABC transporter
CY657_RS05835	COG2040	homocysteine
CY657_RS05840	COG0833	amino acid
CY657_RS05850	COG4303	Ethanolamine ammonia lyase large subunit
CY657_RS05855	COG4302	ethanolamine ammonia-lyase activity
CY657_RS05895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS05900	COG1126	abc transporter atp-binding protein
CY657_RS05905	COG4597	amino acid ABC transporter
CY657_RS05910	COG0765	amino acid transport
CY657_RS05925	COG3188	usher protein
CY657_RS05950	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CY657_RS05960	COG3639	organic phosphonate transmembrane transporter activity
CY657_RS05985	COG0791	NLP P60 protein
CY657_RS06025	COG2909	trisaccharide binding
CY657_RS06030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CY657_RS06035	COG0022	dehydrogenase e1 component
CY657_RS06040	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY657_RS06045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY657_RS06070	COG1070	Carbohydrate kinase
CY657_RS06075	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS06080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY657_RS06085	COG3775	system Galactitol-specific IIC component
CY657_RS06090	COG0625	glutathione transferase activity
CY657_RS06095	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CY657_RS06110	COG0579	oxidoreductase
CY657_RS06115	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS06120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CY657_RS06125	COG1113	amino acid transport
CY657_RS06130	COG1802	Transcriptional regulator
CY657_RS06150	COG2195	Cleaves the N-terminal amino acid of tripeptides
CY657_RS06155	COG0454	-acetyltransferase
CY657_RS06170	COG2991	Protein conserved in bacteria
CY657_RS06185	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CY657_RS06190	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CY657_RS06205	COG3034	peptidoglycan biosynthetic process
CY657_RS06210	COG0121	glutamine amidotransferase
CY657_RS06220	COG1960	acyl-CoA dehydrogenase activity
CY657_RS06225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CY657_RS06235	COG0583	DNA-binding transcription factor activity
CY657_RS06245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY657_RS06255	COG2226	methyltransferase
CY657_RS06265	COG0741	lytic transglycosylase activity
CY657_RS06265	COG1388	LysM domain
CY657_RS06270	COG2226	methyltransferase
CY657_RS06280	COG2814	Major facilitator Superfamily
CY657_RS06285	COG0583	DNA-binding transcription factor activity
CY657_RS06290	COG0656	L-ascorbic acid biosynthetic process
CY657_RS06325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CY657_RS06335	COG2011	ABC-type metal ion transport system permease component
CY657_RS06340	COG1464	Belongs to the NlpA lipoprotein family
CY657_RS06350	COG1720	tRNA m6t6A37 methyltransferase activity
CY657_RS06360	COG0791	NLP P60 protein
CY657_RS06365	COG3015	lipoprotein NlpE involved in copper resistance
CY657_RS06370	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CY657_RS06385	COG4568	rho-dependent transcription termination
CY657_RS06395	COG0346	lactoylglutathione lyase activity
CY657_RS06400	COG1982	Orn Lys Arg decarboxylase major
CY657_RS06410	COG0587	DNA-directed DNA polymerase activity
CY657_RS06440	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CY657_RS06450	COG0750	zinc metalloprotease
CY657_RS06455	COG0575	Belongs to the CDS family
CY657_RS06470	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CY657_RS06495	COG0024	Methionine aminopeptidase
CY657_RS06500	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CY657_RS06515	COG3835	regulator
CY657_RS06520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY657_RS06540	COG2860	membrane
CY657_RS06560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS06565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY657_RS06570	COG1120	ATPase activity
CY657_RS06575	COG4774	siderophore transport
CY657_RS06580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY657_RS06665	COG1643	Atp-dependent helicase
CY657_RS06670	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CY657_RS06690	COG0617	tRNA 3'-terminal CCA addition
CY657_RS06695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CY657_RS06715	COG0726	polysaccharide deacetylase
CY657_RS06720	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS06725	COG0842	Transport permease protein
CY657_RS06730	COG1131	(ABC) transporter
CY657_RS06735	COG0288	reversible hydration of carbon dioxide
CY657_RS06745	COG4993	Dehydrogenase
CY657_RS06750	COG2132	Multicopper oxidase
CY657_RS06790	COG3064	Membrane
CY657_RS06805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY657_RS06810	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY657_RS06815	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CY657_RS06820	COG2186	Transcriptional regulator
CY657_RS06825	COG1113	amino acid transport
CY657_RS06830	COG2211	Major facilitator Superfamily
CY657_RS06835	COG3940	Belongs to the glycosyl hydrolase 43 family
CY657_RS06840	COG3725	Membrane protein required for beta-lactamase induction
CY657_RS06845	COG3023	N-Acetylmuramoyl-L-alanine amidase
CY657_RS06855	COG4969	Belongs to the N-Me-Phe pilin family
CY657_RS06860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CY657_RS06865	COG1459	type II secretion system
CY657_RS06890	COG0494	nUDIX hydrolase
CY657_RS06910	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CY657_RS06915	COG0849	cell division
CY657_RS06940	COG0772	Belongs to the SEDS family
CY657_RS06955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CY657_RS06960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CY657_RS06965	COG0768	penicillin binding
CY657_RS06985	COG1609	Transcriptional regulator
CY657_RS06995	COG0028	Belongs to the TPP enzyme family
CY657_RS07045	COG0738	Major facilitator superfamily
CY657_RS07055	COG0583	DNA-binding transcription factor activity
CY657_RS07060	COG2271	Major facilitator Superfamily
CY657_RS07065	COG2814	Major facilitator Superfamily
CY657_RS07085	COG1178	ABC-type Fe3 transport system permease component
CY657_RS07095	COG0586	Pfam SNARE associated Golgi protein
CY657_RS07115	COG0235	Class ii aldolase
CY657_RS07120	COG0417	DNA replication proofreading
CY657_RS07130	COG0564	pseudouridine synthase activity
CY657_RS07140	COG3493	citrate carrier protein
CY657_RS07155	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CY657_RS07160	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CY657_RS07170	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CY657_RS07215	COG0505	Belongs to the CarA family
CY657_RS07280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CY657_RS07305	COG1047	Peptidyl-prolyl cis-trans
CY657_RS07320	COG0196	riboflavin kinase activity
CY657_RS07335	COG0583	DNA-binding transcription factor activity
CY657_RS07360	COG4735	regulation of single-species biofilm formation
CY657_RS07365	COG1584	GPR1 FUN34 yaaH family protein
CY657_RS07370	COG0477	Major facilitator Superfamily
CY657_RS07375	COG0521	Mo-molybdopterin cofactor biosynthetic process
CY657_RS07380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CY657_RS07385	COG1115	amino acid carrier protein
CY657_RS07400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CY657_RS07410	COG0460	homoserine dehydrogenase
CY657_RS07410	COG0527	aspartate kinase activity
CY657_RS07420	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CY657_RS07430	COG0745	RESPONSE REGULATOR receiver
CY657_RS07435	COG4452	Inner membrane protein CreD
CY657_RS07440	COG2205	protein histidine kinase activity
CY657_RS07445	COG0745	RESPONSE REGULATOR receiver
CY657_RS07450	COG3045	CreA protein
CY657_RS07455	COG3708	Transcriptional regulator
CY657_RS07455	COG2207	Transcriptional regulator
CY657_RS07475	COG0741	lytic transglycosylase activity
CY657_RS07480	COG0488	(ABC) transporter
CY657_RS07490	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CY657_RS07495	COG0560	Phosphoserine phosphatase
CY657_RS07500	COG3726	membrane protein affecting hemolysin expression
CY657_RS07530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY657_RS07535	COG0084	hydrolase, TatD family'
CY657_RS07540	COG4667	esterase of the alpha-beta hydrolase superfamily
CY657_RS07550	COG2823	Periplasmic or secreted lipoprotein
CY657_RS07560	COG1011	Hydrolase
CY657_RS07565	COG0456	acetyltransferase
CY657_RS07570	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CY657_RS07600	COG3706	GGDEF domain
CY657_RS07605	COG4114	ferric iron reductase
CY657_RS07610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS07610	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS07615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CY657_RS07620	COG2197	response regulator
CY657_RS07625	COG2197	response regulator
CY657_RS07640	COG2966	Psort location CytoplasmicMembrane, score
CY657_RS07655	COG1484	DNA-dependent DNA replication
CY657_RS07670	COG5464	transposase or invertase
CY657_RS07680	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CY657_RS07685	COG3716	PTS system mannose fructose sorbose family IID component
CY657_RS07690	COG3715	PTS system
CY657_RS07705	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CY657_RS07705	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CY657_RS07710	COG1214	PFAM Peptidase M22, glycoprotease
CY657_RS07710	COG0456	acetyltransferase
CY657_RS07720	COG1737	Transcriptional regulator
CY657_RS07725	COG0800	Aldolase
CY657_RS07730	COG3734	2-keto-3-deoxy-galactonokinase
CY657_RS07745	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CY657_RS07780	COG1846	Transcriptional regulator
CY657_RS07785	COG0179	Fumarylacetoacetate (FAA) hydrolase
CY657_RS07795	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS07800	COG3384	dioxygenase
CY657_RS07810	COG3971	2-oxopent-4-enoate hydratase activity
CY657_RS07830	COG2368	4-hydroxyphenylacetate
CY657_RS07835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CY657_RS07840	COG1966	Carbon starvation protein
CY657_RS07845	COG2879	small protein
CY657_RS07850	COG0523	cobalamin synthesis protein
CY657_RS07860	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS07865	COG5464	transposase or invertase
CY657_RS07870	COG2207	Transcriptional regulator
CY657_RS07870	COG1917	Cupin 2, conserved barrel domain protein
CY657_RS07880	COG2733	membrane
CY657_RS07895	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CY657_RS07900	COG1924	4 iron, 4 sulfur cluster binding
CY657_RS07915	COG1566	PFAM secretion protein HlyD family protein
CY657_RS07925	COG5457	Domain of unknown function (DUF1127)
CY657_RS07930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY657_RS07940	COG0583	DNA-binding transcription factor activity
CY657_RS07945	COG2249	NAD(P)H dehydrogenase (quinone) activity
CY657_RS07955	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS07960	COG1129	ABC transporter
CY657_RS07965	COG1879	ABC-type sugar transport system periplasmic component
CY657_RS07975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS07980	COG0842	Transport permease protein
CY657_RS07980	COG1129	ABC transporter
CY657_RS07985	COG0842	Transport permease protein
CY657_RS08020	COG2850	peptidyl-arginine hydroxylation
CY657_RS08035	COG5002	protein histidine kinase activity
CY657_RS08040	COG0745	RESPONSE REGULATOR receiver
CY657_RS08045	COG1538	Outer membrane efflux protein
CY657_RS08050	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS08055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS08060	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS08070	COG3040	lipid binding
CY657_RS08075	COG0789	Transcriptional regulator
CY657_RS08085	COG0300	oxidoreductase activity
CY657_RS08100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CY657_RS08120	COG3272	Protein of unknown function (DUF1722)
CY657_RS08125	COG4580	involved in the transport of maltose and maltodextrins
CY657_RS08130	COG2115	Belongs to the xylose isomerase family
CY657_RS08135	COG2211	Major facilitator Superfamily
CY657_RS08140	COG3507	Belongs to the glycosyl hydrolase 43 family
CY657_RS08160	COG1216	Glycosyl transferase, family 2
CY657_RS08215	COG1715	Restriction endonuclease
CY657_RS08230	COG2003	Belongs to the UPF0758 family
CY657_RS08255	COG2378	regulation of single-species biofilm formation
CY657_RS08260	COG3596	GTP binding
CY657_RS08310	COG0210	DNA helicase
CY657_RS08315	COG1111	helicase
CY657_RS08315	COG1205	dead DEAH box helicase
CY657_RS08330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CY657_RS08360	COG0582	viral genome integration into host DNA
CY657_RS08375	COG0288	reversible hydration of carbon dioxide
CY657_RS08380	COG0659	secondary active sulfate transmembrane transporter activity
CY657_RS08385	COG1064	alcohol dehydrogenase
CY657_RS08390	COG1175	transmembrane transport
CY657_RS08395	COG0395	ABC-type sugar transport system, permease component
CY657_RS08400	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CY657_RS08405	COG3842	ATPase activity
CY657_RS08420	COG1082	Xylose isomerase domain protein TIM barrel
CY657_RS08430	COG3962	Belongs to the TPP enzyme family
CY657_RS08435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS08440	COG0837	glucose binding
CY657_RS08440	COG1737	Transcriptional regulator
CY657_RS08455	COG3718	enzyme involved in inositol metabolism
CY657_RS08470	COG0433	COG0433 Predicted ATPase
CY657_RS08475	COG0795	lipopolysaccharide-transporting ATPase activity
CY657_RS08480	COG0795	lipopolysaccharide-transporting ATPase activity
CY657_RS08490	COG2927	DNA polymerase III (CHI subunit)
CY657_RS08495	COG0525	valine-tRNA ligase activity
CY657_RS08520	COG2188	Transcriptional regulator
CY657_RS08525	COG1288	antiporter activity
CY657_RS08530	COG1228	amidohydrolase
CY657_RS08535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS08540	COG2222	sugar isomerase
CY657_RS08545	COG2731	YhcH YjgK YiaL family protein
CY657_RS08585	COG1263	PTS System
CY657_RS08585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS08590	COG0366	Alpha amylase catalytic
CY657_RS08595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS08600	COG1486	melibiose metabolic process
CY657_RS08620	COG0602	queuosine metabolic process
CY657_RS08625	COG2026	Addiction module toxin, RelE StbE family
CY657_RS08630	COG3077	Addiction module antitoxin, RelB DinJ family
CY657_RS08635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS08635	COG3711	transcriptional antiterminator
CY657_RS08655	COG3964	amidohydrolase
CY657_RS08690	COG0312	modulator of DNA gyrase
CY657_RS08710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CY657_RS08720	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS08725	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS08730	COG1129	ABC transporter
CY657_RS08735	COG1879	ABC-type sugar transport system periplasmic component
CY657_RS08755	COG2105	PFAM AIG2 family protein
CY657_RS08760	COG2911	Protein conserved in bacteria
CY657_RS08765	COG0729	surface antigen
CY657_RS08775	COG1253	flavin adenine dinucleotide binding
CY657_RS08790	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CY657_RS08805	COG1733	regulation of RNA biosynthetic process
CY657_RS08810	COG0702	epimerase
CY657_RS08820	COG0697	spore germination
CY657_RS08830	COG1113	amino acid transport
CY657_RS08835	COG0545	Peptidyl-prolyl cis-trans isomerase
CY657_RS08840	COG3061	Opacity-associated protein A
CY657_RS08850	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CY657_RS08855	COG2965	DNA replication, synthesis of RNA primer
CY657_RS08915	COG1073	alpha beta
CY657_RS08920	COG3650	response to hydrogen peroxide
CY657_RS08930	COG1960	acyl-CoA dehydrogenase activity
CY657_RS08935	COG0754	glutathionylspermidine amidase activity
CY657_RS08945	COG3766	membrane
CY657_RS08955	COG1842	Phage shock protein A
CY657_RS08960	COG3789	protein conserved in bacteria
CY657_RS08965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY657_RS08970	COG0557	exoribonuclease II activity
CY657_RS08985	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CY657_RS08995	COG0330	HflC and HflK could
CY657_RS09000	COG0330	HflC and HflK could
CY657_RS09005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CY657_RS09025	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY657_RS09030	COG0802	atpase or kinase
CY657_RS09035	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CY657_RS09035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CY657_RS09040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CY657_RS09060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS09080	COG3264	Mechanosensitive ion channel
CY657_RS09080	COG1511	domain protein
CY657_RS09095	COG1053	succinate dehydrogenase
CY657_RS09100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CY657_RS09120	COG2076	Multidrug Resistance protein
CY657_RS09125	COG5510	response to toxic substance
CY657_RS09140	COG1509	lysine 2,3-aminomutase activity
CY657_RS09145	COG0745	RESPONSE REGULATOR receiver
CY657_RS09180	COG3188	usher protein
CY657_RS09185	COG3539	Fimbrial protein
CY657_RS09210	COG0531	amino acid
CY657_RS09215	COG3030	protein affecting phage T7 exclusion by the F plasmid
CY657_RS09220	COG1027	Aspartate ammonia-lyase
CY657_RS09225	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CY657_RS09240	COG1309	transcriptional regulator
CY657_RS09300	COG0457	Tetratricopeptide repeat
CY657_RS09305	COG1649	PFAM Uncharacterised BCR, COG1649
CY657_RS09305	COG0726	polysaccharide deacetylase
CY657_RS09310	COG1215	transferase activity, transferring glycosyl groups
CY657_RS09330	COG0861	Integral membrane protein TerC family
CY657_RS09360	COG1486	melibiose metabolic process
CY657_RS09365	COG2169	Transcriptional regulator
CY657_RS09380	COG2824	Alkylphosphonate utilization operon protein PhnA
CY657_RS09385	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CY657_RS09390	COG2188	Transcriptional regulator
CY657_RS09395	COG3624	Phosphonate C-P lyase system protein PhnG
CY657_RS09400	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CY657_RS09405	COG3626	phosphonate metabolism
CY657_RS09410	COG3627	carbon phosphorus lyase activity
CY657_RS09415	COG4107	phosphonate C-P lyase system protein PhnK
CY657_RS09420	COG4778	phosphonate C-P lyase system protein PhnL
CY657_RS09425	COG3454	Phosphonate metabolism
CY657_RS09435	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CY657_RS09445	COG4191	Histidine kinase
CY657_RS09445	COG0784	Response regulator, receiver
CY657_RS09450	COG1129	ABC transporter
CY657_RS09455	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS09490	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CY657_RS09495	COG1301	dicarboxylic acid transport
CY657_RS09505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CY657_RS09510	COG3162	membrane
CY657_RS09540	COG3539	Fimbrial protein
CY657_RS09545	COG1346	cytolysis
CY657_RS09550	COG1380	Effector of murein hydrolase LrgA
CY657_RS09555	COG0583	DNA-binding transcription factor activity
CY657_RS09560	COG0025	NhaP-type Na H and K H
CY657_RS09565	COG2252	PERMEase
CY657_RS09570	COG0625	glutathione transferase activity
CY657_RS09575	COG0789	Transcriptional regulator
CY657_RS09585	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CY657_RS09620	COG1234	tRNA 3'-trailer cleavage
CY657_RS09625	COG1609	Transcriptional regulator
CY657_RS09630	COG0483	inositol monophosphate 1-phosphatase activity
CY657_RS09645	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CY657_RS09665	COG4771	TonB-dependent receptor
CY657_RS09670	COG0741	lytic transglycosylase activity
CY657_RS09685	COG2315	Protein conserved in bacteria
CY657_RS09690	COG0432	Pfam Uncharacterised protein family UPF0047
CY657_RS09705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CY657_RS09710	COG0305	Participates in initiation and elongation during chromosome replication
CY657_RS09725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CY657_RS09735	COG0735	belongs to the Fur family
CY657_RS09740	COG3237	CsbD-like
CY657_RS09745	COG0534	Mate efflux family protein
CY657_RS09755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CY657_RS09825	COG0251	oxidation-reduction process
CY657_RS09835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CY657_RS09845	COG0527	aspartate kinase activity
CY657_RS09900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CY657_RS09930	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CY657_RS09940	COG0456	acetyltransferase
CY657_RS09970	COG0151	Belongs to the GarS family
CY657_RS09980	COG4191	Histidine kinase
CY657_RS09985	COG3678	ATP-independent chaperone mediated protein folding
CY657_RS10020	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CY657_RS10035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CY657_RS10040	COG2104	thiamine diphosphate biosynthetic process
CY657_RS10055	COG3706	GGDEF domain
CY657_RS10065	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS10070	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CY657_RS10105	COG0250	Participates in transcription elongation, termination and antitermination
CY657_RS10150	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CY657_RS10180	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CY657_RS10190	COG1739	Uncharacterized protein family UPF0029
CY657_RS10230	COG0805	protein transport
CY657_RS10250	COG3165	ubiquinone biosynthetic process from chorismate
CY657_RS10275	COG0641	radical SAM
CY657_RS10285	COG2149	membrane
CY657_RS10290	COG2188	Transcriptional regulator
CY657_RS10310	COG0583	DNA-binding transcription factor activity
CY657_RS10315	COG0697	spore germination
CY657_RS10320	COG0561	phosphatase activity
CY657_RS10325	COG2267	carboxylic ester hydrolase activity
CY657_RS10330	COG1280	lysine exporter protein (LysE YggA)
CY657_RS10340	COG1280	lysine exporter protein (LysE YggA)
CY657_RS10370	COG0210	DNA helicase
CY657_RS10375	COG1011	Hydrolase
CY657_RS10405	COG3072	Adenylate cyclase
CY657_RS10420	COG2959	enzyme of heme biosynthesis
CY657_RS10425	COG3071	HemY protein
CY657_RS10470	COG2244	polysaccharide biosynthetic process
CY657_RS10475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CY657_RS10480	COG0456	acetyltransferase
CY657_RS10485	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CY657_RS10490	COG1088	dTDP-glucose 4,6-dehydratase activity
CY657_RS10495	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CY657_RS10500	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CY657_RS10510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CY657_RS10515	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CY657_RS10525	COG3118	belongs to the thioredoxin family
CY657_RS10550	COG1811	Na channel or pump
CY657_RS10560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CY657_RS10565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CY657_RS10575	COG0583	DNA-binding transcription factor activity
CY657_RS10580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CY657_RS10595	COG3978	acetolactate synthase activity
CY657_RS10615	COG3085	chromosome segregation
CY657_RS10690	COG0583	DNA-binding transcription factor activity
CY657_RS10705	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CY657_RS10720	COG3443	Belongs to the bacterial solute-binding protein 9 family
CY657_RS10725	COG2207	Transcriptional regulator
CY657_RS10735	COG0371	Dehydrogenase
CY657_RS10740	COG0697	spore germination
CY657_RS10750	COG0583	DNA-binding transcription factor activity
CY657_RS10765	COG0737	Belongs to the 5'-nucleotidase family
CY657_RS10775	COG0527	aspartate kinase activity
CY657_RS10775	COG0460	homoserine dehydrogenase
CY657_RS10780	COG0626	cystathionine gamma-synthase activity
CY657_RS10795	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CY657_RS10800	COG1609	Transcriptional regulator
CY657_RS10805	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CY657_RS10820	COG1575	Belongs to the MenA family. Type 1 subfamily
CY657_RS10840	COG3678	ATP-independent chaperone mediated protein folding
CY657_RS10845	COG0745	RESPONSE REGULATOR receiver
CY657_RS10850	COG2205	protein histidine kinase activity
CY657_RS10855	COG2258	MOSC domain
CY657_RS10860	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CY657_RS10905	COG1129	ABC transporter
CY657_RS10910	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS10915	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS10920	COG1454	alcohol dehydrogenase
CY657_RS10930	COG2211	Major facilitator Superfamily
CY657_RS10990	COG0205	6-phosphofructokinase activity
CY657_RS11010	COG0437	4 iron, 4 sulfur cluster binding
CY657_RS11015	COG2864	formate dehydrogenase
CY657_RS11030	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CY657_RS11040	COG0456	acetyltransferase
CY657_RS11055	COG1011	Hydrolase
CY657_RS11070	COG3852	Histidine kinase
CY657_RS11085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CY657_RS11110	COG0204	Acyl-transferase
CY657_RS11120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CY657_RS11125	COG3084	Protein conserved in bacteria
CY657_RS11135	COG1763	Mo-molybdopterin cofactor biosynthetic process
CY657_RS11165	COG2186	Transcriptional regulator
CY657_RS11170	COG0477	Major facilitator Superfamily
CY657_RS11175	COG1609	Transcriptional regulator
CY657_RS11180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS11190	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS11195	COG1129	ABC transporter
CY657_RS11225	COG1522	sequence-specific DNA binding
CY657_RS11230	COG0716	FMN binding
CY657_RS11245	COG3312	ion transport
CY657_RS11300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CY657_RS11305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CY657_RS11310	COG0573	inorganic phosphate transmembrane transporter activity
CY657_RS11315	COG0581	inorganic phosphate transmembrane transporter activity
CY657_RS11320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CY657_RS11325	COG0704	Plays a role in the regulation of phosphate uptake
CY657_RS11340	COG2382	esterase
CY657_RS11345	COG0363	glucosamine-6-phosphate deaminase activity
CY657_RS11350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS11360	COG2252	PERMEase
CY657_RS11365	COG0431	NADPH-dependent FMN reductase
CY657_RS11370	COG2091	lysine biosynthetic process via aminoadipic acid
CY657_RS11400	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CY657_RS11430	COG0187	DNA topoisomerase II activity
CY657_RS11435	COG0561	phosphatase activity
CY657_RS11450	COG2186	Transcriptional regulator
CY657_RS11455	COG3734	2-keto-3-deoxy-galactonokinase
CY657_RS11460	COG0800	Aldolase
CY657_RS11470	COG2271	Major facilitator Superfamily
CY657_RS11475	COG0823	Involved in the tonB-independent uptake of proteins
CY657_RS11480	COG5645	(Lipo)protein
CY657_RS11495	COG3645	SOS response
CY657_RS11505	COG2188	Transcriptional regulator
CY657_RS11520	COG2149	membrane
CY657_RS11540	COG2610	gluconate transmembrane transporter activity
CY657_RS11545	COG0583	DNA-binding transcription factor activity
CY657_RS11550	COG2814	Major facilitator Superfamily
CY657_RS11575	COG0028	Belongs to the TPP enzyme family
CY657_RS11580	COG0440	acetolactate synthase activity
CY657_RS11585	COG2197	response regulator
CY657_RS11595	COG2271	Major facilitator Superfamily
CY657_RS11645	COG2188	Transcriptional regulator
CY657_RS11670	COG4580	involved in the transport of maltose and maltodextrins
CY657_RS11675	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS11680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS11680	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS11690	COG1609	Transcriptional regulator
CY657_RS11700	COG3384	dioxygenase
CY657_RS11705	COG0583	DNA-binding transcription factor activity
CY657_RS11710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CY657_RS11715	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CY657_RS11720	COG2828	Protein conserved in bacteria
CY657_RS11735	COG0697	spore germination
CY657_RS11740	COG1263	PTS System
CY657_RS11740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS11750	COG2814	Major facilitator Superfamily
CY657_RS11760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS11795	COG0583	DNA-binding transcription factor activity
CY657_RS11820	COG1464	Belongs to the NlpA lipoprotein family
CY657_RS11835	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CY657_RS11845	COG1064	alcohol dehydrogenase
CY657_RS11880	COG2211	Major facilitator Superfamily
CY657_RS11885	COG1501	Belongs to the glycosyl hydrolase 31 family
CY657_RS11895	COG1486	melibiose metabolic process
CY657_RS11900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS11900	COG1263	PTS System
CY657_RS11905	COG2982	Protein involved in outer membrane biogenesis
CY657_RS11910	COG2233	PERMEase
CY657_RS11915	COG0786	glutamate:sodium symporter activity
CY657_RS11935	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CY657_RS11960	COG3152	Membrane
CY657_RS11970	COG1494	fructose-1,6-bisphosphatase
CY657_RS11975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CY657_RS11980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY657_RS11985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CY657_RS12005	COG2860	membrane
CY657_RS12015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CY657_RS12015	COG2169	Transcriptional regulator
CY657_RS12020	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CY657_RS12025	COG1561	YicC-like family, N-terminal region
CY657_RS12040	COG1131	(ABC) transporter
CY657_RS12045	COG0842	Transport permease protein
CY657_RS12075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CY657_RS12110	COG1519	Transferase
CY657_RS12115	COG1216	Glycosyl transferase, family 2
CY657_RS12120	COG0438	transferase activity, transferring glycosyl groups
CY657_RS12130	COG0859	PFAM glycosyl transferase family 9
CY657_RS12155	COG0859	PFAM glycosyl transferase family 9
CY657_RS12170	COG0156	8-amino-7-oxononanoate synthase activity
CY657_RS12180	COG0463	Glycosyl transferase, family 2
CY657_RS12185	COG2861	carbohydrate metabolic process
CY657_RS12190	COG4942	peptidase
CY657_RS12200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CY657_RS12205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CY657_RS12225	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CY657_RS12235	COG2186	Transcriptional regulator
CY657_RS12255	COG3722	fumarate hydratase activity
CY657_RS12275	COG0625	glutathione transferase activity
CY657_RS12285	COG3276	selenocysteine insertion sequence binding
CY657_RS12290	COG1414	Transcriptional regulator
CY657_RS12295	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS12300	COG3977	Valine--pyruvate aminotransferase
CY657_RS12305	COG0366	Alpha amylase catalytic
CY657_RS12310	COG2992	FlgJ-related protein
CY657_RS12315	COG1609	Transcriptional regulator
CY657_RS12315	COG2207	Transcriptional regulator
CY657_RS12320	COG4214	carbohydrate transport
CY657_RS12330	COG4213	ABC transporter substrate-binding protein
CY657_RS12345	COG4682	membrane
CY657_RS12350	COG4682	membrane
CY657_RS12355	COG3274	enterobacterial common antigen metabolic process
CY657_RS12385	COG1278	Cold shock
CY657_RS12390	COG2944	sequence-specific DNA binding
CY657_RS12395	COG2814	Major facilitator Superfamily
CY657_RS12420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS12430	COG1609	Transcriptional regulator
CY657_RS12435	COG2885	chlorophyll binding
CY657_RS12440	COG0243	molybdopterin cofactor binding
CY657_RS12445	COG0456	acetyltransferase
CY657_RS12450	COG2818	Glycosylase
CY657_RS12455	COG5571	outer membrane autotransporter
CY657_RS12460	COG2223	nitrite transmembrane transporter activity
CY657_RS12495	COG0747	negative chemotaxis
CY657_RS12500	COG0601	transmembrane transport
CY657_RS12505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS12510	COG0444	Belongs to the ABC transporter superfamily
CY657_RS12515	COG4608	Belongs to the ABC transporter superfamily
CY657_RS12530	COG2894	cell division
CY657_RS12545	COG0457	Tetratricopeptide repeat
CY657_RS12560	COG2194	sulfuric ester hydrolase activity
CY657_RS12590	COG1215	transferase activity, transferring glycosyl groups
CY657_RS12595	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CY657_RS12600	COG0457	Tetratricopeptide repeat
CY657_RS12600	COG3118	belongs to the thioredoxin family
CY657_RS12605	COG2200	EAL domain
CY657_RS12605	COG2199	diguanylate cyclase activity
CY657_RS12615	COG0612	Peptidase, M16
CY657_RS12630	COG2982	Protein involved in outer membrane biogenesis
CY657_RS12635	COG0477	Major facilitator Superfamily
CY657_RS12640	COG1295	ribonuclease BN
CY657_RS12645	COG0583	DNA-binding transcription factor activity
CY657_RS12650	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS12655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY657_RS12665	COG1454	alcohol dehydrogenase
CY657_RS12675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY657_RS12680	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CY657_RS12685	COG0671	phosphoesterase, PA-phosphatase related
CY657_RS12705	COG0589	response to stress
CY657_RS12715	COG0306	phosphate transporter
CY657_RS12720	COG2081	HI0933 family
CY657_RS12725	COG2239	Acts as a magnesium transporter
CY657_RS12735	COG1124	(ABC) transporter
CY657_RS12745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS12750	COG0601	transmembrane transport
CY657_RS12755	COG0747	negative chemotaxis
CY657_RS12765	COG3479	Phenolic acid decarboxylase
CY657_RS12805	COG0628	permease
CY657_RS12810	COG0477	Major facilitator Superfamily
CY657_RS12820	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CY657_RS12835	COG3714	YhhN family
CY657_RS12845	COG3776	membrane
CY657_RS12850	COG0742	ribosomal rna small subunit methyltransferase
CY657_RS12855	COG0552	protein localization to endoplasmic reticulum
CY657_RS12860	COG2884	Cell division ATP-binding protein ftsE
CY657_RS12865	COG2177	Part of the ABC transporter FtsEX involved in
CY657_RS12880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CY657_RS12890	COG0683	leucine binding
CY657_RS12905	COG0683	leucine binding
CY657_RS12910	COG0559	Belongs to the binding-protein-dependent transport system permease family
CY657_RS12960	COG0584	glycerophosphoryl diester phosphodiesterase
CY657_RS12970	COG0405	Gamma-glutamyltransferase
CY657_RS12975	COG1247	-acetyltransferase
CY657_RS12985	COG0673	inositol 2-dehydrogenase activity
CY657_RS12990	COG1741	Belongs to the pirin family
CY657_RS12995	COG1609	Transcriptional regulator
CY657_RS13000	COG3265	gluconokinase activity
CY657_RS13005	COG2610	gluconate transmembrane transporter activity
CY657_RS13015	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CY657_RS13040	COG0058	SHG alpha-glucan phosphorylase activity
CY657_RS13055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CY657_RS13070	COG1349	DNA-binding transcription factor activity
CY657_RS13080	COG0058	SHG alpha-glucan phosphorylase activity
CY657_RS13085	COG1640	4-alpha-glucanotransferase
CY657_RS13090	COG2610	gluconate transmembrane transporter activity
CY657_RS13100	COG1040	competence protein
CY657_RS13125	COG1918	ferrous iron import across plasma membrane
CY657_RS13130	COG2183	response to ionizing radiation
CY657_RS13135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CY657_RS13160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CY657_RS13165	COG1011	Hydrolase
CY657_RS13175	COG0494	nUDIX hydrolase
CY657_RS13180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CY657_RS13205	COG4796	Type ii and iii secretion system protein
CY657_RS13220	COG3266	domain, Protein
CY657_RS13225	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CY657_RS13230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CY657_RS13255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CY657_RS13260	COG0402	S-adenosylhomocysteine deaminase activity
CY657_RS13265	COG0738	Major facilitator superfamily
CY657_RS13290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CY657_RS13295	COG1289	transmembrane transporter activity
CY657_RS13305	COG1765	OsmC-like protein
CY657_RS13310	COG3954	Phosphoribulokinase
CY657_RS13320	COG0429	hydrolase of the alpha beta-hydrolase fold
CY657_RS13330	COG0488	(ABC) transporter
CY657_RS13345	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CY657_RS13350	COG1047	Peptidyl-prolyl cis-trans
CY657_RS13360	COG0545	Peptidyl-prolyl cis-trans isomerase
CY657_RS13365	COG2964	Protein conserved in bacteria
CY657_RS13420	COG0051	transcription antitermination factor activity, RNA binding
CY657_RS13445	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CY657_RS13460	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CY657_RS13525	COG0201	protein transport
CY657_RS13550	COG0202	RNA polymerase activity
CY657_RS13565	COG0789	Transcriptional regulator
CY657_RS13570	COG3036	rescue of stalled ribosome
CY657_RS13600	COG0758	DNA mediated transformation
CY657_RS13610	COG0551	DNA topoisomerase type I activity
CY657_RS13630	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CY657_RS13665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS13670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS13675	COG1309	transcriptional regulator
CY657_RS13700	COG4145	pantothenate transmembrane transporter activity
CY657_RS13705	COG3924	membrane
CY657_RS13710	COG0439	Biotin carboxylase
CY657_RS13715	COG0511	ligase activity, forming carbon-carbon bonds
CY657_RS13740	COG2200	EAL domain
CY657_RS13740	COG2199	diguanylate cyclase activity
CY657_RS13745	COG1077	Cell shape determining protein MreB Mrl
CY657_RS13750	COG1792	Involved in formation and maintenance of cell shape
CY657_RS13755	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CY657_RS13765	COG1530	ribonuclease E activity
CY657_RS13770	COG3164	Protein of unknown function
CY657_RS13775	COG0312	modulator of DNA gyrase
CY657_RS13780	COG0583	DNA-binding transcription factor activity
CY657_RS13795	COG1289	transmembrane transporter activity
CY657_RS13800	COG2732	(Barnase) inhibitor
CY657_RS13825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY657_RS13830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY657_RS13835	COG3105	Protein conserved in bacteria
CY657_RS13840	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CY657_RS13860	COG0625	glutathione transferase activity
CY657_RS13865	COG2969	positive regulation of protein catabolic process
CY657_RS13875	COG0493	'glutamate synthase
CY657_RS13880	COG0070	glutamate synthase
CY657_RS13880	COG0067	glutamate synthase
CY657_RS13880	COG0069	glutamate synthase activity
CY657_RS13885	COG1242	4 iron, 4 sulfur cluster binding
CY657_RS13890	COG2271	Major facilitator Superfamily
CY657_RS13895	COG1063	alcohol dehydrogenase
CY657_RS13900	COG1312	Catalyzes the dehydration of D-mannonate
CY657_RS13905	COG5002	protein histidine kinase activity
CY657_RS13905	COG0784	Response regulator, receiver
CY657_RS13905	COG2198	Histidine kinase
CY657_RS13910	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CY657_RS13915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY657_RS13920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS13930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS13935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CY657_RS13940	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CY657_RS13945	COG1137	ATPase activity
CY657_RS13950	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CY657_RS13955	COG3117	lipopolysaccharide transmembrane transporter activity
CY657_RS13960	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CY657_RS13970	COG0530	calcium, potassium:sodium antiporter activity
CY657_RS13980	COG1127	ABC transporter
CY657_RS13985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CY657_RS13990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CY657_RS13995	COG2854	intermembrane phospholipid transfer
CY657_RS14000	COG3113	response to antibiotic
CY657_RS14005	COG5007	Belongs to the BolA IbaG family
CY657_RS14015	COG3423	Transcriptional regulator
CY657_RS14020	COG0142	geranyltranstransferase activity
CY657_RS14035	COG0697	spore germination
CY657_RS14045	COG2027	D-alanyl-D-alanine carboxypeptidase
CY657_RS14055	COG1534	Rna-binding protein
CY657_RS14065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CY657_RS14070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CY657_RS14080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CY657_RS14120	COG0195	Participates in both transcription termination and antitermination
CY657_RS14165	COG0814	amino acid
CY657_RS14190	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CY657_RS14235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS14240	COG0826	peptidase U32
CY657_RS14245	COG0826	peptidase U32
CY657_RS14250	COG3154	lipid carrier protein
CY657_RS14255	COG3153	acetyltransferase
CY657_RS14270	COG0693	protein deglycase activity
CY657_RS14275	COG0702	epimerase
CY657_RS14280	COG0701	Predicted permease
CY657_RS14285	COG2823	Periplasmic or secreted lipoprotein
CY657_RS14305	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CY657_RS14310	COG2721	sulfolactate sulfo-lyase activity
CY657_RS14320	COG2271	Major facilitator Superfamily
CY657_RS14330	COG2084	Dehydrogenase
CY657_RS14335	COG1929	Belongs to the glycerate kinase type-1 family
CY657_RS14360	COG1741	Belongs to the pirin family
CY657_RS14365	COG0583	DNA-binding transcription factor activity
CY657_RS14370	COG3152	Membrane
CY657_RS14375	COG0435	Glutathione S-transferase
CY657_RS14380	COG2259	Doxx family
CY657_RS14390	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CY657_RS14395	COG4575	ribosome binding
CY657_RS14400	COG1422	Protein of unknown function (DUF1090)
CY657_RS14410	COG0586	Pfam SNARE associated Golgi protein
CY657_RS14415	COG2186	Transcriptional regulator
CY657_RS14420	COG2271	Major facilitator Superfamily
CY657_RS14430	COG2721	sulfolactate sulfo-lyase activity
CY657_RS14445	COG0861	Integral membrane protein TerC family
CY657_RS14450	COG0673	inositol 2-dehydrogenase activity
CY657_RS14455	COG1451	nucleotide metabolic process
CY657_RS14475	COG1902	pentaerythritol trinitrate reductase activity
CY657_RS14475	COG0446	pyridine nucleotide-disulphide oxidoreductase
CY657_RS14525	COG1695	Transcriptional regulator
CY657_RS14530	COG2375	cellular response to nickel ion
CY657_RS14545	COG1461	Dihydroxyacetone kinase
CY657_RS14550	COG2376	Dihydroxyacetone kinase
CY657_RS14620	COG3247	response to pH
CY657_RS14635	COG2197	response regulator
CY657_RS14655	COG0582	viral genome integration into host DNA
CY657_RS14725	COG4695	Portal protein
CY657_RS14890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CY657_RS14895	COG0358	DNA primase activity
CY657_RS14900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CY657_RS14960	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CY657_RS14975	COG4991	sh3 domain protein
CY657_RS14980	COG3025	triphosphatase activity
CY657_RS15000	COG2960	long-chain fatty acid transporting porin activity
CY657_RS15015	COG3384	dioxygenase
CY657_RS15020	COG0754	glutathionylspermidine amidase activity
CY657_RS15035	COG0494	nUDIX hydrolase
CY657_RS15040	COG3151	Protein conserved in bacteria
CY657_RS15045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CY657_RS15050	COG3150	esterase
CY657_RS15060	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CY657_RS15065	COG2249	NAD(P)H dehydrogenase (quinone) activity
CY657_RS15070	COG0642	Histidine kinase
CY657_RS15080	COG3111	PFAM Bacterial OB fold (BOF) protein
CY657_RS15085	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CY657_RS15090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CY657_RS15095	COG0204	Acyl-transferase
CY657_RS15100	COG2132	Multicopper oxidase
CY657_RS15105	COG1032	radical SAM domain protein
CY657_RS15115	COG0656	L-ascorbic acid biosynthetic process
CY657_RS15120	COG1979	alcohol dehydrogenase
CY657_RS15125	COG2207	Transcriptional regulator
CY657_RS15130	COG0586	Pfam SNARE associated Golgi protein
CY657_RS15135	COG0626	cystathionine gamma-synthase activity
CY657_RS15145	COG0848	biopolymer transport protein
CY657_RS15150	COG2211	Major facilitator Superfamily
CY657_RS15175	COG0625	glutathione transferase activity
CY657_RS15185	COG0754	glutathionylspermidine amidase activity
CY657_RS15190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY657_RS15210	COG0583	DNA-binding transcription factor activity
CY657_RS15215	COG0626	cystathionine gamma-synthase activity
CY657_RS15230	COG1811	Na channel or pump
CY657_RS15240	COG1982	Orn Lys Arg decarboxylase major
CY657_RS15245	COG2211	Major facilitator Superfamily
CY657_RS15260	COG1194	a g-specific adenine glycosylase
CY657_RS15270	COG3171	Protein conserved in bacteria
CY657_RS15280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CY657_RS15295	COG0762	integral membrane protein
CY657_RS15300	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CY657_RS15305	COG2805	Type II/IV secretion system protein
CY657_RS15325	COG0189	ligase activity
CY657_RS15330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CY657_RS15335	COG2356	endonuclease I
CY657_RS15345	COG2814	Major facilitator Superfamily
CY657_RS15380	COG0501	Belongs to the peptidase M48B family
CY657_RS15385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CY657_RS15400	COG0191	fructose-bisphosphate aldolase activity
CY657_RS15405	COG0668	transmembrane transport
CY657_RS15415	COG2968	Membrane
CY657_RS15430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY657_RS15435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CY657_RS15455	COG0006	proline dipeptidase activity
CY657_RS15460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CY657_RS15465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CY657_RS15485	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS15490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CY657_RS15510	COG2723	6-phospho-beta-galactosidase activity
CY657_RS15515	COG1737	Transcriptional regulator
CY657_RS15525	COG1272	protein, Hemolysin III
CY657_RS15535	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CY657_RS15545	COG0716	FMN binding
CY657_RS15550	COG4974	Belongs to the 'phage' integrase family
CY657_RS15560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CY657_RS15585	COG4942	peptidase
CY657_RS15595	COG4974	Belongs to the 'phage' integrase family
CY657_RS15605	COG3646	Phage regulatory protein
CY657_RS15625	COG2814	Major facilitator Superfamily
CY657_RS15640	COG0667	Aldo Keto reductase
CY657_RS15680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CY657_RS15685	COG1393	Belongs to the ArsC family
CY657_RS15700	COG1538	Outer membrane efflux protein
CY657_RS15705	COG1289	transmembrane transporter activity
CY657_RS15720	COG3592	Divergent 4Fe-4S mono-cluster
CY657_RS15725	COG2388	GCN5-related N-acetyl-transferase
CY657_RS15735	COG3539	Fimbrial protein
CY657_RS15740	COG3539	Fimbrial protein
CY657_RS15745	COG3539	Fimbrial protein
CY657_RS15750	COG3188	usher protein
CY657_RS15755	COG3121	Chaperone
CY657_RS15760	COG3539	Fimbrial protein
CY657_RS15770	COG4974	Belongs to the 'phage' integrase family
CY657_RS15775	COG0582	viral genome integration into host DNA
CY657_RS15785	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CY657_RS15790	COG1846	Transcriptional regulator
CY657_RS15795	COG0697	spore germination
CY657_RS15845	COG0667	Aldo Keto reductase
CY657_RS15850	COG0814	amino acid
CY657_RS15865	COG0183	Belongs to the thiolase family
CY657_RS15875	COG0823	Involved in the tonB-independent uptake of proteins
CY657_RS15880	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS15885	COG2814	Major facilitator Superfamily
CY657_RS15915	COG3842	ATPase activity
CY657_RS15920	COG0395	ABC-type sugar transport system, permease component
CY657_RS15925	COG1175	transmembrane transport
CY657_RS15930	COG1917	Cupin 2, conserved barrel domain protein
CY657_RS15935	COG1794	racemase activity, acting on amino acids and derivatives
CY657_RS15940	COG0583	DNA-binding transcription factor activity
CY657_RS15950	COG1609	Transcriptional regulator
CY657_RS15955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS15960	COG2723	6-phospho-beta-galactosidase activity
CY657_RS15965	COG2186	Transcriptional regulator
CY657_RS15975	COG1609	Transcriptional regulator
CY657_RS15990	COG0667	Aldo Keto reductase
CY657_RS16000	COG0861	Integral membrane protein TerC family
CY657_RS16035	COG2165	general secretion pathway protein
CY657_RS16040	COG4795	General secretion pathway protein
CY657_RS16050	COG4967	type IV pilus modification protein PilV
CY657_RS16055	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CY657_RS16060	COG1025	Belongs to the peptidase M16 family
CY657_RS16065	COG1074	ATP-dependent DNA helicase activity
CY657_RS16070	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CY657_RS16080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CY657_RS16080	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CY657_RS16085	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY657_RS16090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CY657_RS16120	COG4656	Part of a membrane complex involved in electron transport
CY657_RS16125	COG1454	alcohol dehydrogenase
CY657_RS16125	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS16155	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CY657_RS16320	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CY657_RS16325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CY657_RS16330	COG2166	iron-sulfur cluster assembly
CY657_RS16335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CY657_RS16345	COG0583	DNA-binding transcription factor activity
CY657_RS16350	COG2363	Small membrane protein
CY657_RS16360	COG1349	DNA-binding transcription factor activity
CY657_RS16380	COG0738	Major facilitator superfamily
CY657_RS16385	COG0235	Class ii aldolase
CY657_RS16390	COG1454	alcohol dehydrogenase
CY657_RS16405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS16420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CY657_RS16425	COG2011	ABC-type metal ion transport system permease component
CY657_RS16430	COG1464	Belongs to the NlpA lipoprotein family
CY657_RS16440	COG0477	Major facilitator Superfamily
CY657_RS16450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY657_RS16455	COG1760	l-serine dehydratase
CY657_RS16460	COG0814	amino acid
CY657_RS16465	COG1611	Belongs to the LOG family
CY657_RS16480	COG3098	single-species biofilm formation
CY657_RS16485	COG0564	pseudouridine synthase activity
CY657_RS16490	COG0716	FMN binding
CY657_RS16495	COG2271	Major facilitator Superfamily
CY657_RS16500	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS16505	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS16510	COG1929	Belongs to the glycerate kinase type-1 family
CY657_RS16520	COG4999	Histidine kinase
CY657_RS16520	COG2205	protein histidine kinase activity
CY657_RS16520	COG3850	Histidine kinase
CY657_RS16520	COG3437	response regulator, receiver
CY657_RS16530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CY657_RS16535	COG3956	TIGRFAM MazG family protein
CY657_RS16555	COG0602	queuosine metabolic process
CY657_RS16560	COG0720	synthase
CY657_RS16580	COG2234	aminopeptidase activity
CY657_RS16640	COG4942	peptidase
CY657_RS16640	COG1388	LysM domain
CY657_RS16670	COG0163	prenyltransferase activity
CY657_RS16675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CY657_RS16720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS16725	COG4558	Periplasmic binding protein
CY657_RS16730	COG3720	iron ion transport
CY657_RS16750	COG0679	Auxin Efflux Carrier
CY657_RS16765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY657_RS16770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY657_RS16775	COG1121	(ABC) transporter
CY657_RS16785	COG1609	Transcriptional regulator
CY657_RS16790	COG1940	carbohydrate kinase activity
CY657_RS16795	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS16800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS16805	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS16810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS16820	COG4580	involved in the transport of maltose and maltodextrins
CY657_RS16830	COG2723	6-phospho-beta-galactosidase activity
CY657_RS16840	COG0309	Hydrogenase expression formation protein (HypE)
CY657_RS16845	COG0409	Hydrogenase expression formation protein
CY657_RS16850	COG0298	carbon dioxide binding
CY657_RS16855	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CY657_RS16875	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS16880	COG0651	ATP synthesis coupled electron transport
CY657_RS16885	COG0650	Formate hydrogenlyase subunit 4
CY657_RS16890	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CY657_RS16890	COG3261	NADH dehydrogenase
CY657_RS16895	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY657_RS16900	COG3260	NADH ubiquinone oxidoreductase 20
CY657_RS16910	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CY657_RS16920	COG2723	6-phospho-beta-galactosidase activity
CY657_RS16925	COG1263	PTS System
CY657_RS16925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS16930	COG1609	Transcriptional regulator
CY657_RS16935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS16940	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CY657_RS16945	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CY657_RS16975	COG1349	DNA-binding transcription factor activity
CY657_RS16980	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS16985	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS16995	COG3732	PTS system glucitol sorbitol-specific
CY657_RS17000	COG3730	PTS system glucitol sorbitol-specific
CY657_RS17005	COG2951	lytic endotransglycosylase activity
CY657_RS17015	COG1121	(ABC) transporter
CY657_RS17020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY657_RS17025	COG0803	Belongs to the bacterial solute-binding protein 9 family
CY657_RS17030	COG1546	Belongs to the CinA family
CY657_RS17055	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CY657_RS17085	COG2823	Periplasmic or secreted lipoprotein
CY657_RS17090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS17095	COG1238	metal cluster binding
CY657_RS17115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CY657_RS17120	COG2814	Major facilitator Superfamily
CY657_RS17125	COG1566	PFAM secretion protein HlyD family protein
CY657_RS17130	COG1846	Transcriptional regulator
CY657_RS17140	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CY657_RS17150	COG4176	ABC-type proline glycine betaine transport system permease component
CY657_RS17165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CY657_RS17175	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CY657_RS17180	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS17185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY657_RS17190	COG4575	ribosome binding
CY657_RS17215	COG2916	Histone family protein nucleoid-structuring protein H-NS
CY657_RS17230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CY657_RS17235	COG0640	Transcriptional regulator
CY657_RS17245	COG0583	DNA-binding transcription factor activity
CY657_RS17250	COG3284	Transcriptional regulator
CY657_RS17260	COG3539	Fimbrial protein
CY657_RS17265	COG3121	Chaperone
CY657_RS17285	COG3188	usher protein
CY657_RS17295	COG3539	Fimbrial protein
CY657_RS17300	COG2197	response regulator
CY657_RS17315	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS17325	COG0235	Class ii aldolase
CY657_RS17335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS17370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS17375	COG3708	Transcriptional regulator
CY657_RS17375	COG2207	Transcriptional regulator
CY657_RS17455	COG0582	viral genome integration into host DNA
CY657_RS17470	COG2867	negative regulation of translational initiation
CY657_RS17485	COG0497	DNA recombination
CY657_RS17500	COG4536	flavin adenine dinucleotide binding
CY657_RS17505	COG4137	Cytochrome C assembly protein
CY657_RS17510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CY657_RS17545	COG2885	chlorophyll binding
CY657_RS17550	COG2199	diguanylate cyclase activity
CY657_RS17560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CY657_RS17565	COG1605	Chorismate mutase
CY657_RS17565	COG0287	Prephenate dehydrogenase
CY657_RS17575	COG1605	Chorismate mutase
CY657_RS17575	COG0077	Prephenate dehydratase
CY657_RS17585	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CY657_RS17590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CY657_RS17605	COG0542	response to heat
CY657_RS17635	COG0477	Major facilitator Superfamily
CY657_RS17640	COG5544	Lipoprotein
CY657_RS17645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY657_RS17655	COG3148	PFAM DTW domain containing protein
CY657_RS17660	COG3118	belongs to the thioredoxin family
CY657_RS17665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY657_RS17680	COG0513	Belongs to the DEAD box helicase family
CY657_RS17690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CY657_RS17705	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CY657_RS17710	COG3026	antisigma factor binding
CY657_RS17715	COG3086	response to oxidative stress
CY657_RS17725	COG0681	Belongs to the peptidase S26 family
CY657_RS17745	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CY657_RS17755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS17760	COG1737	Transcriptional regulator
CY657_RS17765	COG0560	Phosphoserine phosphatase
CY657_RS17780	COG0047	phosphoribosylformylglycinamidine synthase activity
CY657_RS17780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CY657_RS17790	COG2205	protein histidine kinase activity
CY657_RS17795	COG3170	Tfp pilus assembly protein FimV
CY657_RS17800	COG2204	response regulator
CY657_RS17805	COG0347	Belongs to the P(II) protein family
CY657_RS17810	COG1017	nitric oxide dioxygenase activity
CY657_RS17810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS17820	COG2259	Doxx family
CY657_RS17825	COG1940	carbohydrate kinase activity
CY657_RS17830	COG0457	Tetratricopeptide repeat
CY657_RS17835	COG0477	Major facilitator Superfamily
CY657_RS17835	COG2814	Major facilitator Superfamily
CY657_RS17840	COG2017	converts alpha-aldose to the beta-anomer
CY657_RS17845	COG2814	Major facilitator Superfamily
CY657_RS17850	COG3711	transcriptional antiterminator
CY657_RS17855	COG3683	transport system, periplasmic component
CY657_RS17860	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CY657_RS17890	COG0822	iron-sulfur transferase activity
CY657_RS17910	COG0633	Ferredoxin
CY657_RS17915	COG2975	iron-sulfur cluster assembly
CY657_RS17935	COG2897	thiosulfate sulfurtransferase activity
CY657_RS17940	COG2373	Large extracellular alpha-helical protein
CY657_RS17945	COG4953	penicillin-binding protein 1C
CY657_RS17980	COG2976	Protein conserved in bacteria
CY657_RS18000	COG1645	bacterial-type flagellum-dependent swarming motility
CY657_RS18010	COG0516	GMP reductase activity
CY657_RS18010	COG0517	IMP dehydrogenase activity
CY657_RS18020	COG3119	arylsulfatase activity
CY657_RS18025	COG0641	radical SAM
CY657_RS18045	COG2200	EAL domain
CY657_RS18060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CY657_RS18075	COG2723	6-phospho-beta-galactosidase activity
CY657_RS18085	COG2233	PERMEase
CY657_RS18100	COG1393	Belongs to the ArsC family
CY657_RS18105	COG4783	chaperone-mediated protein folding
CY657_RS18110	COG0628	permease
CY657_RS18115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CY657_RS18120	COG2716	regulation of RNA biosynthetic process
CY657_RS18130	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CY657_RS18140	COG2321	neutral zinc metallopeptidase
CY657_RS18145	COG1444	tRNA N-acetyltransferase activity
CY657_RS18150	COG0400	carboxylic ester hydrolase activity
CY657_RS18165	COG1393	Belongs to the ArsC family
CY657_RS18175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS18185	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS18185	COG0493	'glutamate synthase
CY657_RS18195	COG5342	invasion associated locus B
CY657_RS18200	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CY657_RS18205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CY657_RS18215	COG4810	utilization protein
CY657_RS18305	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY657_RS18325	COG2837	iron assimilation
CY657_RS18335	COG4150	thiosulfate binding
CY657_RS18340	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CY657_RS18345	COG4208	sulfate ABC transporter
CY657_RS18350	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CY657_RS18360	COG4319	ketosteroid isomerase
CY657_RS18395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CY657_RS18415	COG3530	Putative quorum-sensing-regulated virulence factor
CY657_RS18420	COG0385	Bile acid
CY657_RS18425	COG0583	DNA-binding transcription factor activity
CY657_RS18460	COG3415	Transposase
CY657_RS18465	COG3415	Transposase
CY657_RS18480	COG2199	diguanylate cyclase activity
CY657_RS18480	COG2200	EAL domain
CY657_RS18485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY657_RS18500	COG0667	Aldo Keto reductase
CY657_RS18505	COG3961	Belongs to the TPP enzyme family
CY657_RS18520	COG3279	Response regulator of the LytR AlgR family
CY657_RS18525	COG3275	phosphorelay sensor kinase activity
CY657_RS18535	COG0436	Aminotransferase
CY657_RS18545	COG2807	transmembrane transport
CY657_RS18550	COG0590	tRNA wobble adenosine to inosine editing
CY657_RS18555	COG0583	DNA-binding transcription factor activity
CY657_RS18575	COG2116	formate transmembrane transporter activity
CY657_RS18580	COG2853	Lipoprotein
CY657_RS18590	COG3691	Protein conserved in bacteria
CY657_RS18605	COG2062	phosphohistidine phosphatase, SixA
CY657_RS18630	COG0730	response to heat
CY657_RS18635	COG3101	peptidyl-lysine hydroxylation
CY657_RS18650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CY657_RS18670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CY657_RS18680	COG0586	Pfam SNARE associated Golgi protein
CY657_RS18690	COG0285	dihydrofolate synthase activity
CY657_RS18695	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CY657_RS18700	COG1286	toxin biosynthetic process
CY657_RS18705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CY657_RS18710	COG0163	prenyltransferase activity
CY657_RS18730	COG4160	amino acid transport
CY657_RS18735	COG4598	ABC transporter
CY657_RS18745	COG1090	epimerase
CY657_RS18750	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CY657_RS18755	COG0625	glutathione transferase activity
CY657_RS18760	COG0625	glutathione transferase activity
CY657_RS18765	COG0622	Phosphoesterase
CY657_RS18770	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CY657_RS18775	COG0857	belongs to the CobB CobQ family
CY657_RS18775	COG0280	phosphate acetyltransferase
CY657_RS18795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS18800	COG0471	metal ion transport
CY657_RS18800	COG0490	domain, Protein
CY657_RS18810	COG0436	Aminotransferase
CY657_RS18815	COG0583	DNA-binding transcription factor activity
CY657_RS18865	COG0839	Belongs to the complex I subunit 6 family
CY657_RS18875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CY657_RS18880	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY657_RS18895	COG2153	protein acetylation
CY657_RS18900	COG1169	isochorismate synthase
CY657_RS18925	COG0318	PFAM AMP-dependent synthetase and ligase
CY657_RS18935	COG5464	transposase or invertase
CY657_RS18950	COG1414	Transcriptional regulator
CY657_RS18960	COG2271	Major facilitator Superfamily
CY657_RS18970	COG0247	lactate metabolic process
CY657_RS18980	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CY657_RS18985	COG2271	Major facilitator Superfamily
CY657_RS18990	COG0584	glycerophosphoryl diester phosphodiesterase
CY657_RS18995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS19020	COG0784	Response regulator, receiver
CY657_RS19020	COG2205	protein histidine kinase activity
CY657_RS19030	COG2198	Histidine kinase
CY657_RS19030	COG0642	Histidine kinase
CY657_RS19045	COG2169	Transcriptional regulator
CY657_RS19045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CY657_RS19050	COG3145	DNA-N1-methyladenine dioxygenase activity
CY657_RS19055	COG4615	Cyclic peptide transporter
CY657_RS19060	COG2239	Acts as a magnesium transporter
CY657_RS19065	COG0659	secondary active sulfate transmembrane transporter activity
CY657_RS19080	COG0628	permease
CY657_RS19105	COG1349	DNA-binding transcription factor activity
CY657_RS19110	COG0494	nUDIX hydrolase
CY657_RS19130	COG1061	Type III restriction enzyme res subunit
CY657_RS19135	COG1187	pseudouridine synthase activity
CY657_RS19140	COG2814	Major facilitator Superfamily
CY657_RS19150	COG4172	Belongs to the ABC transporter superfamily
CY657_RS19155	COG4239	(ABC) transporter, permease
CY657_RS19160	COG4174	ABC transporter (Permease)
CY657_RS19165	COG4166	transmembrane transport
CY657_RS19170	COG2200	EAL domain
CY657_RS19175	COG0791	NLP P60 protein
CY657_RS19180	COG0671	phosphoesterase, PA-phosphatase related
CY657_RS19185	COG0523	cobalamin synthesis protein
CY657_RS19190	COG0246	Mannitol dehydrogenase
CY657_RS19195	COG1312	Catalyzes the dehydration of D-mannonate
CY657_RS19215	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS19215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS19220	COG1105	Belongs to the carbohydrate kinase PfkB family
CY657_RS19225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CY657_RS19225	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CY657_RS19225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CY657_RS19235	COG2855	membrane
CY657_RS19240	COG0583	DNA-binding transcription factor activity
CY657_RS19245	COG0833	amino acid
CY657_RS19255	COG4771	TonB-dependent receptor
CY657_RS19270	COG2311	Membrane
CY657_RS19285	COG1129	ABC transporter
CY657_RS19295	COG2949	membrane
CY657_RS19305	COG1346	cytolysis
CY657_RS19315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CY657_RS19320	COG3659	wide pore channel activity
CY657_RS19335	COG2723	6-phospho-beta-galactosidase activity
CY657_RS19345	COG1538	Outer membrane efflux protein
CY657_RS19350	COG0586	Pfam SNARE associated Golgi protein
CY657_RS19360	COG1686	Belongs to the peptidase S11 family
CY657_RS19370	COG0277	FAD linked oxidase domain protein
CY657_RS19375	COG1472	Belongs to the glycosyl hydrolase 3 family
CY657_RS19380	COG1732	Glycine betaine
CY657_RS19385	COG1174	glycine betaine transport
CY657_RS19390	COG1125	glycine betaine transport
CY657_RS19395	COG1174	glycine betaine transport
CY657_RS19405	COG3275	phosphorelay sensor kinase activity
CY657_RS19415	COG4807	Protein conserved in bacteria
CY657_RS19435	COG5455	response to cobalt ion
CY657_RS19440	COG0583	DNA-binding transcription factor activity
CY657_RS19445	COG2252	PERMEase
CY657_RS19455	COG0583	DNA-binding transcription factor activity
CY657_RS19470	COG0351	phosphomethylpyrimidine kinase
CY657_RS19475	COG1830	Aldolase
CY657_RS19485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CY657_RS19510	COG1070	Carbohydrate kinase
CY657_RS19520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS19525	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS19530	COG0747	negative chemotaxis
CY657_RS19535	COG0601	transmembrane transport
CY657_RS19540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS19545	COG0444	Belongs to the ABC transporter superfamily
CY657_RS19550	COG4608	Belongs to the ABC transporter superfamily
CY657_RS19560	COG0826	peptidase U32
CY657_RS19565	COG0745	RESPONSE REGULATOR receiver
CY657_RS19570	COG2205	protein histidine kinase activity
CY657_RS19595	COG1301	dicarboxylic acid transport
CY657_RS19615	COG5002	protein histidine kinase activity
CY657_RS19620	COG0443	Heat shock 70 kDa protein
CY657_RS19625	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CY657_RS19640	COG2982	Protein involved in outer membrane biogenesis
CY657_RS19645	COG1253	flavin adenine dinucleotide binding
CY657_RS19680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CY657_RS19705	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CY657_RS19710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY657_RS19715	COG1051	belongs to the nudix hydrolase family
CY657_RS19720	COG0297	glycogen (starch) synthase activity
CY657_RS19800	COG0438	transferase activity, transferring glycosyl groups
CY657_RS19805	COG1216	Glycosyl transferase, family 2
CY657_RS19805	COG1442	glycosyl transferase family 8
CY657_RS19815	COG0463	Glycosyl transferase, family 2
CY657_RS19840	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CY657_RS19870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY657_RS19875	COG0583	DNA-binding transcription factor activity
CY657_RS19885	COG0531	amino acid
CY657_RS19890	COG0640	Transcriptional regulator
CY657_RS19895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CY657_RS19900	COG2925	Exonuclease
CY657_RS19915	COG1289	transmembrane transporter activity
CY657_RS19935	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CY657_RS19945	COG1942	4-Oxalocrotonate Tautomerase
CY657_RS19950	COG0583	DNA-binding transcription factor activity
CY657_RS19955	COG0095	Lipoate-protein ligase
CY657_RS19960	COG0477	Major facilitator Superfamily
CY657_RS19975	COG3300	MHYT domain
CY657_RS19975	COG5001	Diguanylate cyclase
CY657_RS19985	COG3615	Tellurite resistance protein tehB
CY657_RS20010	COG3706	GGDEF domain
CY657_RS20040	COG3423	Transcriptional regulator
CY657_RS20080	COG0758	DNA mediated transformation
CY657_RS20140	COG3504	Conjugal transfer protein
CY657_RS20145	COG3736	Type IV secretory pathway, component VirB8
CY657_RS20165	COG3451	type IV secretory pathway VirB4
CY657_RS20185	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CY657_RS20245	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS20250	COG4221	oxidoreductase activity
CY657_RS20255	COG2207	Transcriptional regulator
CY657_RS20265	COG1959	2 iron, 2 sulfur cluster binding
CY657_RS20275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS20280	COG0582	viral genome integration into host DNA
CY657_RS20290	COG0534	Mate efflux family protein
CY657_RS20300	COG0582	viral genome integration into host DNA
CY657_RS20415	COG2916	Histone family protein nucleoid-structuring protein H-NS
CY657_RS20450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CY657_RS20470	COG0604	alcohol dehydrogenase
CY657_RS20475	COG1309	transcriptional regulator
CY657_RS20480	COG0025	NhaP-type Na H and K H
CY657_RS20530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CY657_RS20545	COG1418	mRNA catabolic process
CY657_RS20550	COG0270	DNA (cytosine-5-)-methyltransferase activity
CY657_RS20555	COG3727	T/G mismatch-specific endonuclease activity
CY657_RS20560	COG0697	spore germination
CY657_RS20565	COG2354	Protein conserved in bacteria
CY657_RS20595	COG0366	Alpha amylase catalytic
CY657_RS20600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS20610	COG0765	amino acid transport
CY657_RS20615	COG1126	abc transporter atp-binding protein
CY657_RS20620	COG2197	response regulator
CY657_RS20630	COG2197	response regulator
CY657_RS20670	COG3012	SEC-C Motif Domain Protein
CY657_RS20670	COG3318	Belongs to the UPF0149 family
CY657_RS20675	COG0814	amino acid
CY657_RS20685	COG1528	Iron-storage protein
CY657_RS20700	COG0477	Major facilitator Superfamily
CY657_RS20710	COG2211	Major facilitator Superfamily
CY657_RS20720	COG1528	Iron-storage protein
CY657_RS20730	COG1879	ABC-type sugar transport system periplasmic component
CY657_RS20740	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS20765	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CY657_RS20775	COG3102	Protein conserved in bacteria
CY657_RS20795	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CY657_RS20800	COG1801	Protein of unknown function DUF72
CY657_RS20805	COG1335	isochorismatase
CY657_RS20815	COG0494	nUDIX hydrolase
CY657_RS20840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY657_RS20850	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CY657_RS20855	COG0739	heme binding
CY657_RS20860	COG1560	Kdo2-lipid A biosynthetic process
CY657_RS20870	COG1737	Transcriptional regulator
CY657_RS20885	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CY657_RS20890	COG0129	dihydroxy-acid dehydratase activity
CY657_RS20895	COG0800	Aldolase
CY657_RS20905	COG3141	response to X-ray
CY657_RS20910	COG2979	Protein of unknown function (DUF533)
CY657_RS20915	COG1770	oligopeptidase
CY657_RS20920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY657_RS20930	COG2372	response to copper ion
CY657_RS20935	COG1276	copper resistance
CY657_RS20950	COG2990	Protein conserved in bacteria
CY657_RS20975	COG3008	intermembrane lipid transfer
CY657_RS20980	COG2995	paraquat-inducible protein a
CY657_RS20985	COG1956	GAF domain-containing protein
CY657_RS21005	COG2814	Major facilitator Superfamily
CY657_RS21010	COG1414	Transcriptional regulator
CY657_RS21050	COG0768	penicillin binding
CY657_RS21055	COG2226	methyltransferase
CY657_RS21070	COG3716	PTS system mannose fructose sorbose family IID component
CY657_RS21075	COG3715	PTS system
CY657_RS21080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS21080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS21085	COG1253	flavin adenine dinucleotide binding
CY657_RS21090	COG2200	EAL domain
CY657_RS21095	COG1760	l-serine dehydratase
CY657_RS21115	COG0251	oxidation-reduction process
CY657_RS21120	COG1199	ATP-dependent helicase activity
CY657_RS21130	COG3065	identical protein binding
CY657_RS21140	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CY657_RS21150	COG2894	cell division
CY657_RS21165	COG0179	Fumarylacetoacetate (FAA) hydrolase
CY657_RS21195	COG2719	SpoVR family
CY657_RS21215	COG1619	proteins homologs of microcin C7 resistance protein MccF
CY657_RS21240	COG2308	Evidence 4 Homologs of previously reported genes of
CY657_RS21285	COG0583	DNA-binding transcription factor activity
CY657_RS21290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CY657_RS21305	COG1882	Formate acetyltransferase
CY657_RS21335	COG0583	DNA-binding transcription factor activity
CY657_RS21365	COG0583	DNA-binding transcription factor activity
CY657_RS21380	COG3122	Protein conserved in bacteria
CY657_RS21405	COG2885	chlorophyll binding
CY657_RS21465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CY657_RS21475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CY657_RS21540	COG0012	GTP binding
CY657_RS21560	COG0659	secondary active sulfate transmembrane transporter activity
CY657_RS21590	COG2890	protein-(glutamine-N5) methyltransferase activity
CY657_RS21610	COG0387	Pfam Sodium calcium exchanger
CY657_RS21615	COG4572	Cation transport regulator
CY657_RS21620	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CY657_RS21630	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CY657_RS21635	COG3707	response regulator
CY657_RS21640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY657_RS21650	COG1116	anion transmembrane transporter activity
CY657_RS21655	COG2146	nitrite reductase [NAD(P)H] activity
CY657_RS21655	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CY657_RS21660	COG0243	molybdopterin cofactor binding
CY657_RS21665	COG4932	domain protein
CY657_RS21670	COG2197	response regulator
CY657_RS21675	COG3850	Histidine kinase
CY657_RS21680	COG2223	nitrite transmembrane transporter activity
CY657_RS21685	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CY657_RS21690	COG1140	nitrate reductase beta subunit
CY657_RS21695	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CY657_RS21700	COG2181	nitrate reductase activity
CY657_RS21710	COG1522	sequence-specific DNA binding
CY657_RS21740	COG0788	formyltetrahydrofolate deformylase activity
CY657_RS21750	COG1752	Esterase of the alpha-beta hydrolase superfamily
CY657_RS21755	COG0745	RESPONSE REGULATOR receiver
CY657_RS21760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CY657_RS21765	COG2916	Histone family protein nucleoid-structuring protein H-NS
CY657_RS21770	COG1435	thymidine kinase activity
CY657_RS21775	COG1454	alcohol dehydrogenase
CY657_RS21775	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS21785	COG2095	MarC family integral membrane protein
CY657_RS21790	COG4166	transmembrane transport
CY657_RS21795	COG0601	transmembrane transport
CY657_RS21800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS21805	COG0444	Belongs to the ABC transporter superfamily
CY657_RS21815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CY657_RS21835	COG2353	YceI-like domain
CY657_RS21845	COG2350	Protein conserved in bacteria
CY657_RS21855	COG3001	Fructosamine kinase
CY657_RS21865	COG1105	Belongs to the carbohydrate kinase PfkB family
CY657_RS21870	COG3137	Salt-induced outer membrane protein
CY657_RS21915	COG0072	phenylalanine-tRNA ligase activity
CY657_RS21915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CY657_RS21935	COG0583	DNA-binding transcription factor activity
CY657_RS21955	COG0386	Belongs to the glutathione peroxidase family
CY657_RS21965	COG0791	NLP P60 protein
CY657_RS21975	COG4256	Hemin uptake protein
CY657_RS21980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CY657_RS21990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CY657_RS21990	COG0574	Belongs to the PEP-utilizing enzyme family
CY657_RS22000	COG0628	permease
CY657_RS22005	COG0277	FAD linked oxidase domain protein
CY657_RS22005	COG0247	lactate metabolic process
CY657_RS22010	COG2050	protein possibly involved in aromatic compounds catabolism
CY657_RS22015	COG2261	transglycosylase associated protein
CY657_RS22045	COG1120	ATPase activity
CY657_RS22050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS22060	COG0583	DNA-binding transcription factor activity
CY657_RS22085	COG1304	FMN binding
CY657_RS22090	COG1309	transcriptional regulator
CY657_RS22105	COG0316	Belongs to the HesB IscA family
CY657_RS22110	COG0719	Fe-S assembly protein
CY657_RS22115	COG0396	ATPase activity
CY657_RS22120	COG0719	Fe-S assembly protein
CY657_RS22135	COG1376	ErfK ybiS ycfS ynhG family protein
CY657_RS22160	COG1309	transcriptional regulator
CY657_RS22165	COG1082	Xylose isomerase domain protein TIM barrel
CY657_RS22165	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CY657_RS22170	COG2271	Major facilitator Superfamily
CY657_RS22175	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CY657_RS22185	COG1120	ATPase activity
CY657_RS22190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS22195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY657_RS22200	COG1414	Transcriptional regulator
CY657_RS22235	COG2814	Major facilitator Superfamily
CY657_RS22255	COG0583	DNA-binding transcription factor activity
CY657_RS22260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS22280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS22285	COG1116	anion transmembrane transporter activity
CY657_RS22290	COG4774	siderophore transport
CY657_RS22295	COG1120	ATPase activity
CY657_RS22300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS22305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS22325	COG0765	amino acid transport
CY657_RS22330	COG1126	abc transporter atp-binding protein
CY657_RS22360	COG1473	amidohydrolase
CY657_RS22365	COG3383	formate dehydrogenase (NAD+) activity
CY657_RS22370	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CY657_RS22385	COG1175	transmembrane transport
CY657_RS22420	COG1857	crispr-associated protein
CY657_RS22430	COG1518	maintenance of DNA repeat elements
CY657_RS22435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY657_RS22440	COG3157	Type VI secretion system effector, Hcp
CY657_RS22470	COG4133	protoheme IX ABC transporter activity
CY657_RS22475	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CY657_RS22480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CY657_RS22495	COG1138	Cytochrome C-type biogenesis protein
CY657_RS22505	COG3088	subunit of a heme lyase
CY657_RS22505	COG4235	cytochrome complex assembly
CY657_RS22525	COG5002	protein histidine kinase activity
CY657_RS22525	COG3850	Histidine kinase
CY657_RS22530	COG0745	RESPONSE REGULATOR receiver
CY657_RS22545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS22580	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS22585	COG2610	gluconate transmembrane transporter activity
CY657_RS22590	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY657_RS22600	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CY657_RS22610	COG0583	DNA-binding transcription factor activity
CY657_RS22630	COG0277	FAD linked oxidase domain protein
CY657_RS22635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS22660	COG0402	S-adenosylhomocysteine deaminase activity
CY657_RS22670	COG0583	DNA-binding transcription factor activity
CY657_RS22715	COG4608	Belongs to the ABC transporter superfamily
CY657_RS22720	COG0444	Belongs to the ABC transporter superfamily
CY657_RS22745	COG0346	lactoylglutathione lyase activity
CY657_RS22750	COG1349	DNA-binding transcription factor activity
CY657_RS22780	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CY657_RS22840	COG0307	riboflavin synthase, alpha
CY657_RS22845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CY657_RS22850	COG2814	Major facilitator Superfamily
CY657_RS22855	COG0583	DNA-binding transcription factor activity
CY657_RS22870	COG2814	Major facilitator Superfamily
CY657_RS22885	COG0791	NLP P60 protein
CY657_RS22890	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CY657_RS22900	COG0346	lactoylglutathione lyase activity
CY657_RS22905	COG1902	pentaerythritol trinitrate reductase activity
CY657_RS22910	COG1309	transcriptional regulator
CY657_RS22915	COG3313	Fe-S protein
CY657_RS22920	COG4989	oxidoreductase activity
CY657_RS22925	COG2032	superoxide dismutase activity
CY657_RS22930	COG1289	transmembrane transporter activity
CY657_RS22935	COG1566	PFAM secretion protein HlyD family protein
CY657_RS22950	COG3706	GGDEF domain
CY657_RS22965	COG3895	Periplasmic Protein
CY657_RS22980	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CY657_RS22985	COG0625	glutathione transferase activity
CY657_RS23000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CY657_RS23010	COG4659	FMN binding
CY657_RS23045	COG2723	6-phospho-beta-galactosidase activity
CY657_RS23055	COG0673	inositol 2-dehydrogenase activity
CY657_RS23065	COG2814	Major facilitator Superfamily
CY657_RS23085	COG3038	cytochrome b561
CY657_RS23105	COG0583	DNA-binding transcription factor activity
CY657_RS23110	COG3485	protocatechuate 3,4-dioxygenase
CY657_RS23115	COG3485	protocatechuate 3,4-dioxygenase
CY657_RS23120	COG5383	Protein conserved in bacteria
CY657_RS23125	COG2272	Belongs to the type-B carboxylesterase lipase family
CY657_RS23140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY657_RS23145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CY657_RS23150	COG1275	C4-dicarboxylate transporter malic acid transport protein
CY657_RS23155	COG0500	methyltransferase
CY657_RS23170	COG2207	Transcriptional regulator
CY657_RS23170	COG3708	Transcriptional regulator
CY657_RS23175	COG3135	benzoate transporter
CY657_RS23180	COG1396	sequence-specific DNA binding
CY657_RS23190	COG0826	peptidase U32
CY657_RS23210	COG1294	oxidase, subunit
CY657_RS23215	COG1271	oxidase subunit
CY657_RS23220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY657_RS23225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CY657_RS23230	COG3842	ATPase activity
CY657_RS23235	COG1176	ABC-type spermidine putrescine transport system, permease component I
CY657_RS23240	COG1177	transmembrane transport
CY657_RS23245	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS23280	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS23285	COG0747	negative chemotaxis
CY657_RS23295	COG3238	Protein conserved in bacteria
CY657_RS23300	COG1247	-acetyltransferase
CY657_RS23310	COG2130	NADP-dependent
CY657_RS23325	COG3691	Protein conserved in bacteria
CY657_RS23330	COG1228	amidohydrolase
CY657_RS23335	COG4772	TonB-dependent receptor
CY657_RS23360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CY657_RS23365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS23370	COG1473	amidohydrolase
CY657_RS23375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS23380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS23390	COG0765	amino acid transport
CY657_RS23395	COG1126	abc transporter atp-binding protein
CY657_RS23405	COG2271	Major facilitator Superfamily
CY657_RS23415	COG1609	Transcriptional regulator
CY657_RS23420	COG0625	glutathione transferase activity
CY657_RS23435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CY657_RS23440	COG3842	ATPase activity
CY657_RS23445	COG1840	ABC-type Fe3 transport system, periplasmic component
CY657_RS23450	COG1178	ABC-type Fe3 transport system permease component
CY657_RS23455	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CY657_RS23460	COG2181	nitrate reductase activity
CY657_RS23465	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CY657_RS23470	COG1140	nitrate reductase beta subunit
CY657_RS23475	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CY657_RS23495	COG1414	Transcriptional regulator
CY657_RS23500	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS23505	COG4829	muconolactone delta-isomerase
CY657_RS23510	COG3485	protocatechuate 3,4-dioxygenase
CY657_RS23520	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CY657_RS23545	COG0437	4 iron, 4 sulfur cluster binding
CY657_RS23550	COG2864	formate dehydrogenase
CY657_RS23565	COG2326	polyphosphate kinase activity
CY657_RS23575	COG2814	Major facilitator Superfamily
CY657_RS23585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS23595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS23605	COG0747	negative chemotaxis
CY657_RS23610	COG1064	alcohol dehydrogenase
CY657_RS23625	COG0488	(ABC) transporter
CY657_RS23665	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS23670	COG3729	General stress protein
CY657_RS23690	COG3685	Protein conserved in bacteria
CY657_RS23700	COG0366	Alpha amylase catalytic
CY657_RS23710	COG2323	membrane
CY657_RS23720	COG3111	PFAM Bacterial OB fold (BOF) protein
CY657_RS23725	COG1764	response to oxidative stress
CY657_RS23750	COG3781	membrane
CY657_RS23755	COG0243	molybdopterin cofactor binding
CY657_RS23760	COG0583	DNA-binding transcription factor activity
CY657_RS23765	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS23770	COG2814	Major facilitator Superfamily
CY657_RS23780	COG1285	pathogenesis
CY657_RS23785	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CY657_RS23795	COG0583	DNA-binding transcription factor activity
CY657_RS23815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CY657_RS23815	COG0519	Catalyzes the synthesis of GMP from XMP
CY657_RS23855	COG0596	Alpha beta hydrolase
CY657_RS23865	COG2205	protein histidine kinase activity
CY657_RS23880	COG0076	glutamate decarboxylase activity
CY657_RS23885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CY657_RS23890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY657_RS23895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS23900	COG1116	anion transmembrane transporter activity
CY657_RS23905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CY657_RS23915	COG0673	inositol 2-dehydrogenase activity
CY657_RS23925	COG1609	Transcriptional regulator
CY657_RS23930	COG3706	GGDEF domain
CY657_RS23935	COG0402	S-adenosylhomocysteine deaminase activity
CY657_RS23940	COG1953	Uracil, thiamine, allantoin
CY657_RS23975	COG0596	Alpha beta hydrolase
CY657_RS23990	COG2207	Transcriptional regulator
CY657_RS24010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CY657_RS24075	COG0765	amino acid transport
CY657_RS24085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CY657_RS24095	COG2070	2-Nitropropane dioxygenase
CY657_RS24100	COG0583	DNA-binding transcription factor activity
CY657_RS24110	COG1902	pentaerythritol trinitrate reductase activity
CY657_RS24115	COG4529	Protein conserved in bacteria
CY657_RS24120	COG0477	Major facilitator Superfamily
CY657_RS24160	COG2223	nitrite transmembrane transporter activity
CY657_RS24170	COG1609	Transcriptional regulator
CY657_RS24175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS24185	COG0583	DNA-binding transcription factor activity
CY657_RS24190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY657_RS24215	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS24225	COG1609	Transcriptional regulator
CY657_RS24255	COG1652	LysM domain
CY657_RS24280	COG0456	acetyltransferase
CY657_RS24280	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CY657_RS24290	COG0667	Aldo Keto reductase
CY657_RS24295	COG0667	Aldo Keto reductase
CY657_RS24300	COG3386	PFAM SMP-30 Gluconolaconase
CY657_RS24305	COG0667	Aldo Keto reductase
CY657_RS24330	COG4977	sequence-specific DNA binding
CY657_RS24360	COG1349	DNA-binding transcription factor activity
CY657_RS24365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CY657_RS24370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS24375	COG0738	Major facilitator superfamily
CY657_RS24420	COG1929	Belongs to the glycerate kinase type-1 family
CY657_RS24425	COG3835	regulator
CY657_RS24445	COG2186	Transcriptional regulator
CY657_RS24450	COG1263	PTS System
CY657_RS24450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS24460	COG2814	Major facilitator Superfamily
CY657_RS24465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS24465	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS24475	COG2819	hydrolase of the alpha beta superfamily
CY657_RS24480	COG3300	MHYT domain
CY657_RS24480	COG5001	Diguanylate cyclase
CY657_RS24515	COG3188	usher protein
CY657_RS24525	COG1649	PFAM Uncharacterised BCR, COG1649
CY657_RS24530	COG3550	peptidyl-serine autophosphorylation
CY657_RS24535	COG1396	sequence-specific DNA binding
CY657_RS24540	COG2351	hydroxyisourate hydrolase activity
CY657_RS24545	COG3648	Uricase
CY657_RS24545	COG3195	allantoin biosynthetic process
CY657_RS24550	COG2233	PERMEase
CY657_RS24580	COG2207	Transcriptional regulator
CY657_RS24595	COG4628	conserved protein (DUF2132)
CY657_RS24615	COG2011	ABC-type metal ion transport system permease component
CY657_RS24620	COG2070	2-Nitropropane dioxygenase
CY657_RS24630	COG0477	Major facilitator Superfamily
CY657_RS24710	COG2199	diguanylate cyclase activity
CY657_RS24725	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS24730	COG0583	DNA-binding transcription factor activity
CY657_RS24740	COG0039	L-malate dehydrogenase activity
CY657_RS24745	COG1349	DNA-binding transcription factor activity
CY657_RS24750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CY657_RS24755	COG3395	kinase activity
CY657_RS24765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CY657_RS24770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY657_RS24775	COG2271	Major facilitator Superfamily
CY657_RS24800	COG4977	sequence-specific DNA binding
CY657_RS24810	COG0697	spore germination
CY657_RS24815	COG2814	Major facilitator Superfamily
CY657_RS24845	COG0683	leucine binding
CY657_RS24850	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CY657_RS24885	COG2223	nitrite transmembrane transporter activity
CY657_RS24890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CY657_RS24905	COG1349	DNA-binding transcription factor activity
CY657_RS24910	COG2084	Dehydrogenase
CY657_RS24915	COG3395	kinase activity
CY657_RS24920	COG0235	Class ii aldolase
CY657_RS24925	COG3622	Belongs to the hyi family
CY657_RS24930	COG2610	gluconate transmembrane transporter activity
CY657_RS24935	COG2207	Transcriptional regulator
CY657_RS24935	COG3708	Transcriptional regulator
CY657_RS24955	COG2200	EAL domain
CY657_RS24960	COG1546	Belongs to the CinA family
CY657_RS24965	COG0071	Belongs to the small heat shock protein (HSP20) family
CY657_RS24990	COG2135	peptidase activity
CY657_RS24995	COG2207	Transcriptional regulator
CY657_RS25010	COG4221	oxidoreductase activity
CY657_RS25015	COG1802	Transcriptional regulator
CY657_RS25020	COG0589	response to stress
CY657_RS25025	COG0246	Mannitol dehydrogenase
CY657_RS25030	COG2271	Major facilitator Superfamily
CY657_RS25045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY657_RS25060	COG0243	molybdopterin cofactor binding
CY657_RS25065	COG0437	4 iron, 4 sulfur cluster binding
CY657_RS25070	COG3302	dmso reductase anchor subunit
CY657_RS25085	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CY657_RS25090	COG1940	carbohydrate kinase activity
CY657_RS25095	COG0583	DNA-binding transcription factor activity
CY657_RS25100	COG2814	Major facilitator Superfamily
CY657_RS25105	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CY657_RS25115	COG3591	Belongs to the peptidase S1B family
CY657_RS25135	COG0628	permease
CY657_RS25165	COG0679	Auxin Efflux Carrier
CY657_RS25175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CY657_RS25200	COG3290	protein histidine kinase activity
CY657_RS25205	COG4565	transcriptional regulatory protein
CY657_RS25225	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CY657_RS25225	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CY657_RS25235	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS25240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CY657_RS25250	COG0183	Belongs to the thiolase family
CY657_RS25255	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CY657_RS25265	COG1414	Transcriptional regulator
CY657_RS25270	COG2840	Smr protein MutS2
CY657_RS25275	COG0583	DNA-binding transcription factor activity
CY657_RS25285	COG1473	amidohydrolase
CY657_RS25290	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CY657_RS25305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CY657_RS25320	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CY657_RS25325	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CY657_RS25345	COG0531	amino acid
CY657_RS25355	COG3136	membrane protein required for alginate biosynthesis
CY657_RS25360	COG0745	RESPONSE REGULATOR receiver
CY657_RS25370	COG2205	protein histidine kinase activity
CY657_RS25380	COG0114	fumarate hydratase activity
CY657_RS25385	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CY657_RS25385	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CY657_RS25390	COG1482	cell wall glycoprotein biosynthetic process
CY657_RS25395	COG5339	Protein conserved in bacteria
CY657_RS25400	COG1609	Transcriptional regulator
CY657_RS25405	COG1263	PTS System
CY657_RS25405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS25410	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CY657_RS25435	COG2391	methyltransferase activity
CY657_RS25440	COG0425	Belongs to the sulfur carrier protein TusA family
CY657_RS25445	COG5562	phage envelope protein
CY657_RS25450	COG0401	homolog of Blt101
CY657_RS25455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CY657_RS25460	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS25465	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CY657_RS25470	COG0477	Major facilitator Superfamily
CY657_RS25475	COG1113	amino acid transport
CY657_RS25480	COG2988	succinylglutamate desuccinylase activity
CY657_RS25485	COG3724	N-succinylarginine dihydrolase activity
CY657_RS25490	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS25495	COG3138	arginine N-succinyltransferase
CY657_RS25500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CY657_RS25505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CY657_RS25510	COG0667	Aldo Keto reductase
CY657_RS25515	COG0583	DNA-binding transcription factor activity
CY657_RS25540	COG4122	O-methyltransferase activity
CY657_RS25545	COG1643	Atp-dependent helicase
CY657_RS25560	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CY657_RS25565	COG3327	negative regulation of DNA-templated transcription, initiation
CY657_RS25570	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CY657_RS25575	COG0183	Belongs to the thiolase family
CY657_RS25580	COG2050	protein possibly involved in aromatic compounds catabolism
CY657_RS25585	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY657_RS25590	COG1024	Enoyl-CoA hydratase
CY657_RS25595	COG1024	Enoyl-CoA hydratase
CY657_RS25600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS25605	COG2151	metal-sulfur cluster biosynthetic enzyme
CY657_RS25610	COG3396	Phenylacetate-CoA oxygenase
CY657_RS25615	COG3460	Phenylacetate-CoA oxygenase
CY657_RS25620	COG3396	Phenylacetate-CoA oxygenase
CY657_RS25625	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS25625	COG2030	dehydratase
CY657_RS25645	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS25650	COG2207	Transcriptional regulator
CY657_RS25655	COG3784	Protein of unknown function (DUF1318)
CY657_RS25665	COG2911	Protein conserved in bacteria
CY657_RS25670	COG0586	Pfam SNARE associated Golgi protein
CY657_RS25675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CY657_RS25680	COG3187	Heat shock protein
CY657_RS25685	COG3042	response to heat
CY657_RS25695	COG1013	pyruvate-flavodoxin oxidoreductase activity
CY657_RS25695	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CY657_RS25695	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY657_RS25695	COG0674	pyruvate-flavodoxin oxidoreductase activity
CY657_RS25700	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CY657_RS25710	COG0589	response to stress
CY657_RS25720	COG0513	Belongs to the DEAD box helicase family
CY657_RS25735	COG1349	DNA-binding transcription factor activity
CY657_RS25740	COG0673	inositol 2-dehydrogenase activity
CY657_RS25755	COG2011	ABC-type metal ion transport system permease component
CY657_RS25770	COG0436	Aminotransferase
CY657_RS25775	COG0604	alcohol dehydrogenase
CY657_RS25800	COG0583	DNA-binding transcription factor activity
CY657_RS25820	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS25825	COG1309	transcriptional regulator
CY657_RS25830	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS25925	COG2885	chlorophyll binding
CY657_RS25950	COG0693	protein deglycase activity
CY657_RS25955	COG1078	dGTPase activity
CY657_RS25960	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS25965	COG0583	DNA-binding transcription factor activity
CY657_RS25985	COG0656	L-ascorbic acid biosynthetic process
CY657_RS26015	COG4166	transmembrane transport
CY657_RS26020	COG2866	Carboxypeptidase
CY657_RS26025	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS26030	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CY657_RS26035	COG3180	Ammonia monooxygenase
CY657_RS26045	COG1486	melibiose metabolic process
CY657_RS26050	COG0583	DNA-binding transcription factor activity
CY657_RS26060	COG3106	COG3106 Predicted ATPase
CY657_RS26070	COG1983	PspC domain protein
CY657_RS26080	COG1842	Phage shock protein A
CY657_RS26085	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CY657_RS26095	COG1473	amidohydrolase
CY657_RS26110	COG0702	epimerase