locus-tag	class	description
CY657_RS00025	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CY657_RS00055	COG2091	lysine biosynthetic process via aminoadipic acid
CY657_RS00060	COG0431	NADPH-dependent FMN reductase
CY657_RS00065	COG2252	PERMEase
CY657_RS00075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS00080	COG0363	glucosamine-6-phosphate deaminase activity
CY657_RS00085	COG2382	esterase
CY657_RS00100	COG0704	Plays a role in the regulation of phosphate uptake
CY657_RS00105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CY657_RS00110	COG0581	inorganic phosphate transmembrane transporter activity
CY657_RS00115	COG0573	inorganic phosphate transmembrane transporter activity
CY657_RS00120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CY657_RS00125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CY657_RS00180	COG3312	ion transport
CY657_RS00195	COG0716	FMN binding
CY657_RS00200	COG1522	sequence-specific DNA binding
CY657_RS00230	COG1129	ABC transporter
CY657_RS00235	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS00245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS00250	COG1609	Transcriptional regulator
CY657_RS00255	COG0477	Major facilitator Superfamily
CY657_RS00260	COG2186	Transcriptional regulator
CY657_RS00290	COG1763	Mo-molybdopterin cofactor biosynthetic process
CY657_RS00300	COG3084	Protein conserved in bacteria
CY657_RS00305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CY657_RS00315	COG0204	Acyl-transferase
CY657_RS00340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CY657_RS00355	COG3852	Histidine kinase
CY657_RS00370	COG1011	Hydrolase
CY657_RS00385	COG0456	acetyltransferase
CY657_RS00395	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CY657_RS00410	COG2864	formate dehydrogenase
CY657_RS00415	COG0437	4 iron, 4 sulfur cluster binding
CY657_RS00435	COG0205	6-phosphofructokinase activity
CY657_RS00495	COG2211	Major facilitator Superfamily
CY657_RS00505	COG1454	alcohol dehydrogenase
CY657_RS00510	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS00515	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS00520	COG1129	ABC transporter
CY657_RS00565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CY657_RS00570	COG2258	MOSC domain
CY657_RS00575	COG2205	protein histidine kinase activity
CY657_RS00580	COG0745	RESPONSE REGULATOR receiver
CY657_RS00585	COG3678	ATP-independent chaperone mediated protein folding
CY657_RS00605	COG1575	Belongs to the MenA family. Type 1 subfamily
CY657_RS00620	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CY657_RS00625	COG1609	Transcriptional regulator
CY657_RS00630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CY657_RS00645	COG0626	cystathionine gamma-synthase activity
CY657_RS00650	COG0460	homoserine dehydrogenase
CY657_RS00650	COG0527	aspartate kinase activity
CY657_RS00660	COG0737	Belongs to the 5'-nucleotidase family
CY657_RS00675	COG0583	DNA-binding transcription factor activity
CY657_RS00685	COG0697	spore germination
CY657_RS00690	COG0371	Dehydrogenase
CY657_RS00700	COG2207	Transcriptional regulator
CY657_RS00705	COG3443	Belongs to the bacterial solute-binding protein 9 family
CY657_RS00720	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CY657_RS00735	COG0583	DNA-binding transcription factor activity
CY657_RS00810	COG3085	chromosome segregation
CY657_RS00830	COG3978	acetolactate synthase activity
CY657_RS00845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CY657_RS00850	COG0583	DNA-binding transcription factor activity
CY657_RS00860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CY657_RS00865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CY657_RS00875	COG1811	Na channel or pump
CY657_RS00900	COG3118	belongs to the thioredoxin family
CY657_RS00910	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CY657_RS00915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CY657_RS00925	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CY657_RS00930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CY657_RS00935	COG1088	dTDP-glucose 4,6-dehydratase activity
CY657_RS00940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CY657_RS00945	COG0456	acetyltransferase
CY657_RS00950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CY657_RS00955	COG2244	polysaccharide biosynthetic process
CY657_RS01000	COG3071	HemY protein
CY657_RS01005	COG2959	enzyme of heme biosynthesis
CY657_RS01020	COG3072	Adenylate cyclase
CY657_RS01050	COG1011	Hydrolase
CY657_RS01055	COG0210	DNA helicase
CY657_RS01085	COG1280	lysine exporter protein (LysE YggA)
CY657_RS01095	COG1280	lysine exporter protein (LysE YggA)
CY657_RS01100	COG2267	carboxylic ester hydrolase activity
CY657_RS01105	COG0561	phosphatase activity
CY657_RS01110	COG0697	spore germination
CY657_RS01115	COG0583	DNA-binding transcription factor activity
CY657_RS01135	COG2188	Transcriptional regulator
CY657_RS01140	COG2149	membrane
CY657_RS01150	COG0641	radical SAM
CY657_RS01175	COG3165	ubiquinone biosynthetic process from chorismate
CY657_RS01195	COG0805	protein transport
CY657_RS01235	COG1739	Uncharacterized protein family UPF0029
CY657_RS01245	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CY657_RS01275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CY657_RS01320	COG0250	Participates in transcription elongation, termination and antitermination
CY657_RS01355	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CY657_RS01360	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS01370	COG3706	GGDEF domain
CY657_RS01385	COG2104	thiamine diphosphate biosynthetic process
CY657_RS01390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CY657_RS01405	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CY657_RS01440	COG3678	ATP-independent chaperone mediated protein folding
CY657_RS01445	COG4191	Histidine kinase
CY657_RS01455	COG0151	Belongs to the GarS family
CY657_RS01485	COG0456	acetyltransferase
CY657_RS01495	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CY657_RS01520	COG1283	sodium-dependent phosphate transmembrane transporter activity
CY657_RS01525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CY657_RS01580	COG0527	aspartate kinase activity
CY657_RS01590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CY657_RS01600	COG0251	oxidation-reduction process
CY657_RS01670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CY657_RS01680	COG0534	Mate efflux family protein
CY657_RS01685	COG3237	CsbD-like
CY657_RS01690	COG0735	belongs to the Fur family
CY657_RS01700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CY657_RS01715	COG0305	Participates in initiation and elongation during chromosome replication
CY657_RS01720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CY657_RS01735	COG0432	Pfam Uncharacterised protein family UPF0047
CY657_RS01740	COG2315	Protein conserved in bacteria
CY657_RS01755	COG0741	lytic transglycosylase activity
CY657_RS01760	COG4771	TonB-dependent receptor
CY657_RS01780	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CY657_RS01795	COG0483	inositol monophosphate 1-phosphatase activity
CY657_RS01800	COG1609	Transcriptional regulator
CY657_RS01805	COG1234	tRNA 3'-trailer cleavage
CY657_RS01840	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CY657_RS01850	COG0789	Transcriptional regulator
CY657_RS01855	COG0625	glutathione transferase activity
CY657_RS01860	COG2252	PERMEase
CY657_RS01865	COG0025	NhaP-type Na H and K H
CY657_RS01870	COG0583	DNA-binding transcription factor activity
CY657_RS01875	COG1380	Effector of murein hydrolase LrgA
CY657_RS01880	COG1346	cytolysis
CY657_RS01885	COG3539	Fimbrial protein
CY657_RS01915	COG3162	membrane
CY657_RS01920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CY657_RS01930	COG1301	dicarboxylic acid transport
CY657_RS01935	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CY657_RS01970	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS01975	COG1129	ABC transporter
CY657_RS01980	COG4191	Histidine kinase
CY657_RS01980	COG0784	Response regulator, receiver
CY657_RS01990	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CY657_RS02000	COG3454	Phosphonate metabolism
CY657_RS02005	COG4778	phosphonate C-P lyase system protein PhnL
CY657_RS02010	COG4107	phosphonate C-P lyase system protein PhnK
CY657_RS02015	COG3627	carbon phosphorus lyase activity
CY657_RS02020	COG3626	phosphonate metabolism
CY657_RS02025	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CY657_RS02030	COG3624	Phosphonate C-P lyase system protein PhnG
CY657_RS02035	COG2188	Transcriptional regulator
CY657_RS02040	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CY657_RS02045	COG2824	Alkylphosphonate utilization operon protein PhnA
CY657_RS02060	COG2169	Transcriptional regulator
CY657_RS02065	COG1486	melibiose metabolic process
CY657_RS02095	COG0861	Integral membrane protein TerC family
CY657_RS02115	COG1215	transferase activity, transferring glycosyl groups
CY657_RS02120	COG0726	polysaccharide deacetylase
CY657_RS02120	COG1649	PFAM Uncharacterised BCR, COG1649
CY657_RS02125	COG0457	Tetratricopeptide repeat
CY657_RS02185	COG1309	transcriptional regulator
CY657_RS02200	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CY657_RS02205	COG1027	Aspartate ammonia-lyase
CY657_RS02210	COG3030	protein affecting phage T7 exclusion by the F plasmid
CY657_RS02215	COG0531	amino acid
CY657_RS02240	COG3539	Fimbrial protein
CY657_RS02245	COG3188	usher protein
CY657_RS02280	COG0745	RESPONSE REGULATOR receiver
CY657_RS02285	COG1509	lysine 2,3-aminomutase activity
CY657_RS02300	COG5510	response to toxic substance
CY657_RS02305	COG2076	Multidrug Resistance protein
CY657_RS02325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CY657_RS02330	COG1053	succinate dehydrogenase
CY657_RS02345	COG3264	Mechanosensitive ion channel
CY657_RS02345	COG1511	domain protein
CY657_RS02365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS02385	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CY657_RS02390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CY657_RS02390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CY657_RS02395	COG0802	atpase or kinase
CY657_RS02400	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY657_RS02420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CY657_RS02425	COG0330	HflC and HflK could
CY657_RS02430	COG0330	HflC and HflK could
CY657_RS02440	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CY657_RS02455	COG0557	exoribonuclease II activity
CY657_RS02460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY657_RS02465	COG3789	protein conserved in bacteria
CY657_RS02470	COG1842	Phage shock protein A
CY657_RS02480	COG3766	membrane
CY657_RS02490	COG0754	glutathionylspermidine amidase activity
CY657_RS02495	COG1960	acyl-CoA dehydrogenase activity
CY657_RS02505	COG3650	response to hydrogen peroxide
CY657_RS02510	COG1073	alpha beta
CY657_RS02570	COG2965	DNA replication, synthesis of RNA primer
CY657_RS02575	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CY657_RS02585	COG3061	Opacity-associated protein A
CY657_RS02590	COG0545	Peptidyl-prolyl cis-trans isomerase
CY657_RS02595	COG1113	amino acid transport
CY657_RS02605	COG0697	spore germination
CY657_RS02615	COG0702	epimerase
CY657_RS02620	COG1733	regulation of RNA biosynthetic process
CY657_RS02635	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CY657_RS02650	COG1253	flavin adenine dinucleotide binding
CY657_RS02660	COG0729	surface antigen
CY657_RS02665	COG2911	Protein conserved in bacteria
CY657_RS02670	COG2105	PFAM AIG2 family protein
CY657_RS02690	COG1879	ABC-type sugar transport system periplasmic component
CY657_RS02695	COG1129	ABC transporter
CY657_RS02700	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS02705	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS02715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CY657_RS02735	COG0312	modulator of DNA gyrase
CY657_RS02770	COG3964	amidohydrolase
CY657_RS02790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS02790	COG3711	transcriptional antiterminator
CY657_RS02795	COG3077	Addiction module antitoxin, RelB DinJ family
CY657_RS02800	COG2026	Addiction module toxin, RelE StbE family
CY657_RS02805	COG0602	queuosine metabolic process
CY657_RS02825	COG1486	melibiose metabolic process
CY657_RS02830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS02835	COG0366	Alpha amylase catalytic
CY657_RS02840	COG1263	PTS System
CY657_RS02840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS02880	COG2731	YhcH YjgK YiaL family protein
CY657_RS02885	COG2222	sugar isomerase
CY657_RS02890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS02895	COG1228	amidohydrolase
CY657_RS02900	COG1288	antiporter activity
CY657_RS02905	COG2188	Transcriptional regulator
CY657_RS02930	COG0525	valine-tRNA ligase activity
CY657_RS02935	COG2927	DNA polymerase III (CHI subunit)
CY657_RS02945	COG0795	lipopolysaccharide-transporting ATPase activity
CY657_RS02950	COG0795	lipopolysaccharide-transporting ATPase activity
CY657_RS02955	COG0433	COG0433 Predicted ATPase
CY657_RS02970	COG3718	enzyme involved in inositol metabolism
CY657_RS02985	COG1737	Transcriptional regulator
CY657_RS02985	COG0837	glucose binding
CY657_RS02990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS02995	COG3962	Belongs to the TPP enzyme family
CY657_RS03005	COG1082	Xylose isomerase domain protein TIM barrel
CY657_RS03020	COG3842	ATPase activity
CY657_RS03025	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CY657_RS03030	COG0395	ABC-type sugar transport system, permease component
CY657_RS03035	COG1175	transmembrane transport
CY657_RS03040	COG1064	alcohol dehydrogenase
CY657_RS03045	COG0659	secondary active sulfate transmembrane transporter activity
CY657_RS03050	COG0288	reversible hydration of carbon dioxide
CY657_RS03065	COG0582	viral genome integration into host DNA
CY657_RS03095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CY657_RS03110	COG1205	dead DEAH box helicase
CY657_RS03110	COG1111	helicase
CY657_RS03115	COG0210	DNA helicase
CY657_RS03165	COG3596	GTP binding
CY657_RS03170	COG2378	regulation of single-species biofilm formation
CY657_RS03195	COG2003	Belongs to the UPF0758 family
CY657_RS03210	COG1715	Restriction endonuclease
CY657_RS03265	COG1216	Glycosyl transferase, family 2
CY657_RS03285	COG3507	Belongs to the glycosyl hydrolase 43 family
CY657_RS03290	COG2211	Major facilitator Superfamily
CY657_RS03295	COG2115	Belongs to the xylose isomerase family
CY657_RS03300	COG4580	involved in the transport of maltose and maltodextrins
CY657_RS03305	COG3272	Protein of unknown function (DUF1722)
CY657_RS03325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CY657_RS03340	COG0300	oxidoreductase activity
CY657_RS03350	COG0789	Transcriptional regulator
CY657_RS03355	COG3040	lipid binding
CY657_RS03365	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS03370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS03375	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS03380	COG1538	Outer membrane efflux protein
CY657_RS03385	COG0745	RESPONSE REGULATOR receiver
CY657_RS03390	COG5002	protein histidine kinase activity
CY657_RS03405	COG2850	peptidyl-arginine hydroxylation
CY657_RS03440	COG0842	Transport permease protein
CY657_RS03445	COG0842	Transport permease protein
CY657_RS03445	COG1129	ABC transporter
CY657_RS03450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS03460	COG1879	ABC-type sugar transport system periplasmic component
CY657_RS03465	COG1129	ABC transporter
CY657_RS03470	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS03480	COG2249	NAD(P)H dehydrogenase (quinone) activity
CY657_RS03485	COG0583	DNA-binding transcription factor activity
CY657_RS03495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY657_RS03500	COG5457	Domain of unknown function (DUF1127)
CY657_RS03510	COG1566	PFAM secretion protein HlyD family protein
CY657_RS03525	COG1924	4 iron, 4 sulfur cluster binding
CY657_RS03530	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CY657_RS03545	COG2733	membrane
CY657_RS03555	COG1917	Cupin 2, conserved barrel domain protein
CY657_RS03555	COG2207	Transcriptional regulator
CY657_RS03560	COG5464	transposase or invertase
CY657_RS03565	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS03575	COG0523	cobalamin synthesis protein
CY657_RS03580	COG2879	small protein
CY657_RS03585	COG1966	Carbon starvation protein
CY657_RS03590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CY657_RS03595	COG2368	4-hydroxyphenylacetate
CY657_RS03615	COG3971	2-oxopent-4-enoate hydratase activity
CY657_RS03625	COG3384	dioxygenase
CY657_RS03630	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS03640	COG0179	Fumarylacetoacetate (FAA) hydrolase
CY657_RS03645	COG1846	Transcriptional regulator
CY657_RS03680	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CY657_RS03695	COG3734	2-keto-3-deoxy-galactonokinase
CY657_RS03700	COG0800	Aldolase
CY657_RS03705	COG1737	Transcriptional regulator
CY657_RS03715	COG1214	PFAM Peptidase M22, glycoprotease
CY657_RS03715	COG0456	acetyltransferase
CY657_RS03720	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CY657_RS03720	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CY657_RS03735	COG3715	PTS system
CY657_RS03740	COG3716	PTS system mannose fructose sorbose family IID component
CY657_RS03745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CY657_RS03755	COG5464	transposase or invertase
CY657_RS03770	COG1484	DNA-dependent DNA replication
CY657_RS03785	COG2966	Psort location CytoplasmicMembrane, score
CY657_RS03800	COG2197	response regulator
CY657_RS03805	COG2197	response regulator
CY657_RS03810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CY657_RS03815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS03815	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS03820	COG4114	ferric iron reductase
CY657_RS03825	COG3706	GGDEF domain
CY657_RS03855	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CY657_RS03860	COG0456	acetyltransferase
CY657_RS03865	COG1011	Hydrolase
CY657_RS03875	COG2823	Periplasmic or secreted lipoprotein
CY657_RS03885	COG4667	esterase of the alpha-beta hydrolase superfamily
CY657_RS03890	COG0084	hydrolase, TatD family'
CY657_RS03895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY657_RS03925	COG3726	membrane protein affecting hemolysin expression
CY657_RS03930	COG0560	Phosphoserine phosphatase
CY657_RS03935	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CY657_RS03945	COG0488	(ABC) transporter
CY657_RS03950	COG0741	lytic transglycosylase activity
CY657_RS03970	COG2207	Transcriptional regulator
CY657_RS03970	COG3708	Transcriptional regulator
CY657_RS03975	COG3045	CreA protein
CY657_RS03980	COG0745	RESPONSE REGULATOR receiver
CY657_RS03985	COG2205	protein histidine kinase activity
CY657_RS03990	COG4452	Inner membrane protein CreD
CY657_RS03995	COG0745	RESPONSE REGULATOR receiver
CY657_RS04005	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CY657_RS04015	COG0460	homoserine dehydrogenase
CY657_RS04015	COG0527	aspartate kinase activity
CY657_RS04025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CY657_RS04040	COG1115	amino acid carrier protein
CY657_RS04045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CY657_RS04050	COG0521	Mo-molybdopterin cofactor biosynthetic process
CY657_RS04055	COG0477	Major facilitator Superfamily
CY657_RS04060	COG1584	GPR1 FUN34 yaaH family protein
CY657_RS04065	COG4735	regulation of single-species biofilm formation
CY657_RS04090	COG0583	DNA-binding transcription factor activity
CY657_RS04105	COG0196	riboflavin kinase activity
CY657_RS04120	COG1047	Peptidyl-prolyl cis-trans
CY657_RS04145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CY657_RS04210	COG0505	Belongs to the CarA family
CY657_RS04255	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CY657_RS04265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CY657_RS04270	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CY657_RS04285	COG3493	citrate carrier protein
CY657_RS04295	COG0564	pseudouridine synthase activity
CY657_RS04305	COG0417	DNA replication proofreading
CY657_RS04310	COG0235	Class ii aldolase
CY657_RS04330	COG0586	Pfam SNARE associated Golgi protein
CY657_RS04340	COG1178	ABC-type Fe3 transport system permease component
CY657_RS04360	COG2814	Major facilitator Superfamily
CY657_RS04365	COG2271	Major facilitator Superfamily
CY657_RS04370	COG0583	DNA-binding transcription factor activity
CY657_RS04380	COG0738	Major facilitator superfamily
CY657_RS04430	COG0028	Belongs to the TPP enzyme family
CY657_RS04440	COG1609	Transcriptional regulator
CY657_RS04460	COG0768	penicillin binding
CY657_RS04465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CY657_RS04470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CY657_RS04485	COG0772	Belongs to the SEDS family
CY657_RS04510	COG0849	cell division
CY657_RS04515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CY657_RS04535	COG0494	nUDIX hydrolase
CY657_RS04560	COG1459	type II secretion system
CY657_RS04565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CY657_RS04570	COG4969	Belongs to the N-Me-Phe pilin family
CY657_RS04580	COG3023	N-Acetylmuramoyl-L-alanine amidase
CY657_RS04585	COG3725	Membrane protein required for beta-lactamase induction
CY657_RS04590	COG3940	Belongs to the glycosyl hydrolase 43 family
CY657_RS04595	COG2211	Major facilitator Superfamily
CY657_RS04600	COG1113	amino acid transport
CY657_RS04605	COG2186	Transcriptional regulator
CY657_RS04610	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CY657_RS04615	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY657_RS04620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY657_RS04635	COG3064	Membrane
CY657_RS04675	COG2132	Multicopper oxidase
CY657_RS04680	COG4993	Dehydrogenase
CY657_RS04690	COG0288	reversible hydration of carbon dioxide
CY657_RS04695	COG1131	(ABC) transporter
CY657_RS04700	COG0842	Transport permease protein
CY657_RS04705	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS04710	COG0726	polysaccharide deacetylase
CY657_RS04730	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CY657_RS04735	COG0617	tRNA 3'-terminal CCA addition
CY657_RS04755	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CY657_RS04760	COG1643	Atp-dependent helicase
CY657_RS04845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY657_RS04850	COG4774	siderophore transport
CY657_RS04855	COG1120	ATPase activity
CY657_RS04860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY657_RS04865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS04885	COG2860	membrane
CY657_RS04905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY657_RS04910	COG3835	regulator
CY657_RS04925	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CY657_RS04930	COG0024	Methionine aminopeptidase
CY657_RS04955	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CY657_RS04970	COG0575	Belongs to the CDS family
CY657_RS04975	COG0750	zinc metalloprotease
CY657_RS04985	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CY657_RS05015	COG0587	DNA-directed DNA polymerase activity
CY657_RS05025	COG1982	Orn Lys Arg decarboxylase major
CY657_RS05030	COG0346	lactoylglutathione lyase activity
CY657_RS05040	COG4568	rho-dependent transcription termination
CY657_RS05055	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CY657_RS05060	COG3015	lipoprotein NlpE involved in copper resistance
CY657_RS05065	COG0791	NLP P60 protein
CY657_RS05075	COG1720	tRNA m6t6A37 methyltransferase activity
CY657_RS05085	COG1464	Belongs to the NlpA lipoprotein family
CY657_RS05090	COG2011	ABC-type metal ion transport system permease component
CY657_RS05100	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CY657_RS05135	COG0656	L-ascorbic acid biosynthetic process
CY657_RS05140	COG0583	DNA-binding transcription factor activity
CY657_RS05145	COG2814	Major facilitator Superfamily
CY657_RS05155	COG2226	methyltransferase
CY657_RS05160	COG1388	LysM domain
CY657_RS05160	COG0741	lytic transglycosylase activity
CY657_RS05170	COG2226	methyltransferase
CY657_RS05180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY657_RS05190	COG0583	DNA-binding transcription factor activity
CY657_RS05200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CY657_RS05205	COG1960	acyl-CoA dehydrogenase activity
CY657_RS05215	COG0121	glutamine amidotransferase
CY657_RS05220	COG3034	peptidoglycan biosynthetic process
CY657_RS05235	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CY657_RS05240	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CY657_RS05255	COG2991	Protein conserved in bacteria
CY657_RS05270	COG0454	-acetyltransferase
CY657_RS05275	COG2195	Cleaves the N-terminal amino acid of tripeptides
CY657_RS05295	COG1802	Transcriptional regulator
CY657_RS05300	COG1113	amino acid transport
CY657_RS05305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CY657_RS05310	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS05315	COG0579	oxidoreductase
CY657_RS05330	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CY657_RS05335	COG0625	glutathione transferase activity
CY657_RS05340	COG3775	system Galactitol-specific IIC component
CY657_RS05345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY657_RS05350	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS05355	COG1070	Carbohydrate kinase
CY657_RS05380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY657_RS05385	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY657_RS05390	COG0022	dehydrogenase e1 component
CY657_RS05395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CY657_RS05400	COG2909	trisaccharide binding
CY657_RS05440	COG0791	NLP P60 protein
CY657_RS05465	COG3639	organic phosphonate transmembrane transporter activity
CY657_RS05475	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CY657_RS05500	COG3188	usher protein
CY657_RS05515	COG0765	amino acid transport
CY657_RS05520	COG4597	amino acid ABC transporter
CY657_RS05525	COG1126	abc transporter atp-binding protein
CY657_RS05530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS05570	COG4302	ethanolamine ammonia-lyase activity
CY657_RS05575	COG4303	Ethanolamine ammonia lyase large subunit
CY657_RS05585	COG0833	amino acid
CY657_RS05590	COG2040	homocysteine
CY657_RS05595	COG4521	taurine ABC transporter
CY657_RS05600	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CY657_RS05605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS05610	COG2175	clavaminate synthase activity
CY657_RS05620	COG0113	porphobilinogen synthase activity
CY657_RS05625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CY657_RS05630	COG1335	isochorismatase
CY657_RS05635	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CY657_RS05675	COG1785	Belongs to the alkaline phosphatase family
CY657_RS05685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CY657_RS05695	COG3416	Protein conserved in bacteria
CY657_RS05700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CY657_RS05710	COG4126	flavin adenine dinucleotide binding
CY657_RS05725	COG1940	carbohydrate kinase activity
CY657_RS05730	COG0419	ATPase involved in DNA repair
CY657_RS05735	COG0420	3'-5' exonuclease activity
CY657_RS05760	COG0366	Alpha amylase catalytic
CY657_RS05765	COG0583	DNA-binding transcription factor activity
CY657_RS05770	COG1335	isochorismatase
CY657_RS05780	COG1228	amidohydrolase
CY657_RS05790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS05805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS05810	COG0450	alkyl hydroperoxide reductase
CY657_RS05830	COG1862	Preprotein translocase
CY657_RS05835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CY657_RS05840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CY657_RS05860	COG4238	major outer membrane lipoprotein
CY657_RS05870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CY657_RS05870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CY657_RS05890	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CY657_RS05895	COG0667	Aldo Keto reductase
CY657_RS05905	COG0142	geranyltranstransferase activity
CY657_RS05925	COG0693	protein deglycase activity
CY657_RS05930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CY657_RS05940	COG2814	Major facilitator Superfamily
CY657_RS05945	COG0673	inositol 2-dehydrogenase activity
CY657_RS05960	COG1053	succinate dehydrogenase
CY657_RS05970	COG1053	succinate dehydrogenase
CY657_RS05975	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CY657_RS05980	COG1414	Transcriptional regulator
CY657_RS05995	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CY657_RS06000	COG1845	cytochrome c oxidase, subunit III
CY657_RS06005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CY657_RS06010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CY657_RS06015	COG2223	nitrite transmembrane transporter activity
CY657_RS06020	COG3056	Lipoprotein
CY657_RS06025	COG0271	Belongs to the BolA IbaG family
CY657_RS06055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CY657_RS06060	COG0776	regulation of translation
CY657_RS06065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CY657_RS06070	COG1555	photosystem II stabilization
CY657_RS06075	COG0824	Thioesterase
CY657_RS06085	COG4533	DNA binding
CY657_RS06100	COG1522	sequence-specific DNA binding
CY657_RS06105	COG1132	(ABC) transporter
CY657_RS06110	COG1132	(ABC) transporter
CY657_RS06115	COG0347	Belongs to the P(II) protein family
CY657_RS06120	COG0004	ammonium transporteR
CY657_RS06125	COG1946	Acyl-CoA thioesterase
CY657_RS06130	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CY657_RS06135	COG3695	enzyme binding
CY657_RS06165	COG2364	Membrane
CY657_RS06180	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CY657_RS06190	COG2182	Extracellular solute-binding protein
CY657_RS06195	COG1175	transmembrane transport
CY657_RS06200	COG3833	ABC-type maltose transport systems, permease component
CY657_RS06205	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CY657_RS06210	COG1874	Beta-galactosidase
CY657_RS06255	COG0110	maltose O-acetyltransferase activity
CY657_RS06270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS06275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS06280	COG1309	transcriptional regulator
CY657_RS06285	COG1196	nuclear chromosome segregation
CY657_RS06285	COG3264	Mechanosensitive ion channel
CY657_RS06300	COG3923	Primosomal replication protein n
CY657_RS06305	COG2832	Protein of unknown function (DUF454)
CY657_RS06345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS06350	COG4651	solute:proton antiporter activity
CY657_RS06350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CY657_RS06355	COG2223	nitrite transmembrane transporter activity
CY657_RS06365	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CY657_RS06370	COG3735	TraB family
CY657_RS06385	COG1585	Membrane protein implicated in regulation of membrane protease activity
CY657_RS06390	COG0330	HflC and HflK could
CY657_RS06395	COG4619	ABC transporter
CY657_RS06400	COG0390	transport system, permease component
CY657_RS06410	COG3118	belongs to the thioredoxin family
CY657_RS06415	COG0300	oxidoreductase activity
CY657_RS06420	COG2755	lipolytic protein G-D-S-L family
CY657_RS06425	COG4181	ATPase activity
CY657_RS06430	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CY657_RS06445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CY657_RS06450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CY657_RS06465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CY657_RS06475	COG2501	S4 domain
CY657_RS06495	COG0582	viral genome integration into host DNA
CY657_RS06655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CY657_RS06885	COG0372	Belongs to the citrate synthase family
CY657_RS06900	COG3539	Fimbrial protein
CY657_RS06905	COG3121	Chaperone
CY657_RS06910	COG3188	usher protein
CY657_RS06925	COG1560	Kdo2-lipid A biosynthetic process
CY657_RS06940	COG3710	Transcriptional regulator
CY657_RS06945	COG0531	amino acid
CY657_RS06950	COG1982	Orn Lys Arg decarboxylase major
CY657_RS06955	COG3104	oligopeptide transport
CY657_RS07000	COG1129	ABC transporter
CY657_RS07005	COG4211	Belongs to the binding-protein-dependent transport system permease family
CY657_RS07050	COG1566	PFAM secretion protein HlyD family protein
CY657_RS07055	COG1120	ATPase activity
CY657_RS07060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS07080	COG1473	amidohydrolase
CY657_RS07085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS07090	COG0667	Aldo Keto reductase
CY657_RS07135	COG0531	amino acid
CY657_RS07145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY657_RS07150	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS07165	COG1113	amino acid transport
CY657_RS07170	COG2211	Major facilitator Superfamily
CY657_RS07180	COG0673	inositol 2-dehydrogenase activity
CY657_RS07190	COG1609	Transcriptional regulator
CY657_RS07195	COG0668	transmembrane transport
CY657_RS07200	COG0477	Major facilitator Superfamily
CY657_RS07215	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CY657_RS07215	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CY657_RS07220	COG2222	sugar isomerase
CY657_RS07225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CY657_RS07230	COG3716	PTS system mannose fructose sorbose family IID component
CY657_RS07240	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS07250	COG0778	Nitroreductase
CY657_RS07255	COG2315	Protein conserved in bacteria
CY657_RS07300	COG3698	Phosphodiester glycosidase
CY657_RS07310	COG4166	transmembrane transport
CY657_RS07320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS07325	COG4608	Belongs to the ABC transporter superfamily
CY657_RS07340	COG0697	spore germination
CY657_RS07355	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CY657_RS07365	COG4215	(ABC) transporter
CY657_RS07375	COG4221	oxidoreductase activity
CY657_RS07380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY657_RS07385	COG4608	Belongs to the ABC transporter superfamily
CY657_RS07390	COG0444	Belongs to the ABC transporter superfamily
CY657_RS07395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS07400	COG0601	transmembrane transport
CY657_RS07405	COG0747	negative chemotaxis
CY657_RS07430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CY657_RS07440	COG0668	transmembrane transport
CY657_RS07445	COG0583	DNA-binding transcription factor activity
CY657_RS07455	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS07465	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS07470	COG1129	ABC transporter
CY657_RS07480	COG1879	ABC-type sugar transport system periplasmic component
CY657_RS07485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CY657_RS07490	COG2390	Transcriptional regulator
CY657_RS07495	COG3959	Transketolase, thiamine diphosphate binding domain
CY657_RS07500	COG3958	Transketolase
CY657_RS07505	COG2977	Belongs to the P-Pant transferase superfamily
CY657_RS07510	COG4771	TonB-dependent receptor
CY657_RS07515	COG2382	esterase
CY657_RS07520	COG3251	PFAM MbtH domain protein
CY657_RS07525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CY657_RS07525	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CY657_RS07530	COG1120	ATPase activity
CY657_RS07535	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS07540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS07550	COG4592	Periplasmic binding protein
CY657_RS07555	COG1169	isochorismate synthase
CY657_RS07560	COG1021	2,3-dihydroxybenzoate-AMP ligase
CY657_RS07565	COG3433	isochorismatase activity
CY657_RS07565	COG1535	isochorismatase
CY657_RS07570	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS07580	COG1966	Carbon starvation protein
CY657_RS07585	COG2879	small protein
CY657_RS07600	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS07605	COG0371	Dehydrogenase
CY657_RS07610	COG1129	ABC transporter
CY657_RS07615	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS07645	COG2271	Major facilitator Superfamily
CY657_RS07650	COG0483	inositol monophosphate 1-phosphatase activity
CY657_RS07660	COG0402	S-adenosylhomocysteine deaminase activity
CY657_RS07670	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CY657_RS07685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY657_RS07695	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS07700	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS07705	COG1129	ABC transporter
CY657_RS07730	COG0436	Aminotransferase
CY657_RS07735	COG1475	DNA binding
CY657_RS07740	COG3969	phosphoadenosine phosphosulfate
CY657_RS07745	COG0583	DNA-binding transcription factor activity
CY657_RS07750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CY657_RS07770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CY657_RS07775	COG3719	Belongs to the RNase T2 family
CY657_RS07780	COG3069	C4-dicarboxylate transmembrane transporter activity
CY657_RS07800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CY657_RS07815	COG0583	DNA-binding transcription factor activity
CY657_RS07830	COG1686	Belongs to the peptidase S11 family
CY657_RS07835	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CY657_RS07840	COG0772	Belongs to the SEDS family
CY657_RS07845	COG0768	penicillin binding
CY657_RS07855	COG0799	negative regulation of ribosome biogenesis
CY657_RS07870	COG1466	dna polymerase III delta subunit
CY657_RS07885	COG2888	peptidyl-tyrosine sulfation
CY657_RS07900	COG1126	abc transporter atp-binding protein
CY657_RS07905	COG0765	amino acid transport
CY657_RS07910	COG0765	amino acid transport
CY657_RS07935	COG1702	phosphate starvation-inducible protein PhoH
CY657_RS07945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CY657_RS07990	COG0367	asparagine synthase
CY657_RS07995	COG0647	UMP catabolic process
CY657_RS08000	COG1846	Transcriptional regulator
CY657_RS08000	COG1940	carbohydrate kinase activity
CY657_RS08005	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CY657_RS08045	COG0735	belongs to the Fur family
CY657_RS08060	COG0596	Alpha beta hydrolase
CY657_RS08070	COG0033	Phosphoglucomutase
CY657_RS08080	COG0745	RESPONSE REGULATOR receiver
CY657_RS08085	COG2205	protein histidine kinase activity
CY657_RS08115	COG0415	Belongs to the DNA photolyase family
CY657_RS08130	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CY657_RS08135	COG1984	allophanate hydrolase subunit 2
CY657_RS08170	COG2009	succinate dehydrogenase
CY657_RS08175	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CY657_RS08180	COG1053	succinate dehydrogenase
CY657_RS08185	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CY657_RS08190	COG0567	Dehydrogenase, E1 component
CY657_RS08195	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY657_RS08205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CY657_RS08215	COG1271	oxidase subunit
CY657_RS08220	COG1294	oxidase, subunit
CY657_RS08225	COG4890	Cyd operon protein YbgT
CY657_RS08230	COG3790	cyd operon protein YbgE
CY657_RS08235	COG0824	Thioesterase
CY657_RS08240	COG0811	peptide transport
CY657_RS08245	COG0848	biopolymer transport protein
CY657_RS08250	COG3064	Membrane
CY657_RS08260	COG2885	chlorophyll binding
CY657_RS08265	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CY657_RS08310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CY657_RS08315	COG3201	nicotinamide mononucleotide transporter
CY657_RS08330	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CY657_RS08340	COG2017	converts alpha-aldose to the beta-anomer
CY657_RS08350	COG1085	galactose-1-phosphate uridylyltransferase
CY657_RS08360	COG1119	ATPase activity
CY657_RS08365	COG3585	molybdate ion transport
CY657_RS08365	COG2005	Transcriptional regulator
CY657_RS08375	COG0725	ABC transporter, periplasmic molybdate-binding protein
CY657_RS08380	COG4149	molybdate abc transporter
CY657_RS08390	COG0561	phosphatase activity
CY657_RS08415	COG2200	EAL domain
CY657_RS08420	COG0789	Transcriptional regulator
CY657_RS08450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS08455	COG0589	response to stress
CY657_RS08470	COG4677	pectinesterase activity
CY657_RS08505	COG1881	PFAM PEBP family protein
CY657_RS08510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY657_RS08525	COG2226	methyltransferase
CY657_RS08560	COG0642	Histidine kinase
CY657_RS08565	COG0745	RESPONSE REGULATOR receiver
CY657_RS08590	COG0521	Mo-molybdopterin cofactor biosynthetic process
CY657_RS08600	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CY657_RS08605	COG0314	molybdopterin synthase activity
CY657_RS08610	COG0670	Belongs to the BI1 family
CY657_RS08620	COG0392	lysyltransferase activity
CY657_RS08625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY657_RS08630	COG3568	Endonuclease Exonuclease Phosphatase
CY657_RS08640	COG0842	Transport permease protein
CY657_RS08645	COG0842	Transport permease protein
CY657_RS08650	COG1131	(ABC) transporter
CY657_RS08655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS08660	COG1309	transcriptional regulator
CY657_RS08665	COG0583	DNA-binding transcription factor activity
CY657_RS08670	COG2271	Major facilitator Superfamily
CY657_RS08675	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS08680	COG3959	Transketolase, thiamine diphosphate binding domain
CY657_RS08685	COG3958	Transketolase
CY657_RS08690	COG0513	Belongs to the DEAD box helicase family
CY657_RS08695	COG1199	ATP-dependent helicase activity
CY657_RS08700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CY657_RS08710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CY657_RS08720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CY657_RS08730	COG0668	transmembrane transport
CY657_RS08735	COG1126	abc transporter atp-binding protein
CY657_RS08740	COG0765	amino acid transport
CY657_RS08745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS08760	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CY657_RS08765	COG2194	sulfuric ester hydrolase activity
CY657_RS08780	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CY657_RS08785	COG2723	6-phospho-beta-galactosidase activity
CY657_RS08790	COG2188	Transcriptional regulator
CY657_RS08795	COG1376	ErfK ybiS ycfS ynhG family protein
CY657_RS08800	COG2365	Tyrosine phosphatase family
CY657_RS08805	COG0488	(ABC) transporter
CY657_RS08815	COG2271	Major facilitator Superfamily
CY657_RS08820	COG1609	Transcriptional regulator
CY657_RS08830	COG0561	phosphatase activity
CY657_RS08835	COG1882	Formate acetyltransferase
CY657_RS08840	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CY657_RS08845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CY657_RS08850	COG0303	'Molybdopterin
CY657_RS08865	COG0747	negative chemotaxis
CY657_RS08885	COG2223	nitrite transmembrane transporter activity
CY657_RS08895	COG2133	pyrroloquinoline quinone binding
CY657_RS08900	COG0625	glutathione transferase activity
CY657_RS08905	COG1686	Belongs to the peptidase S11 family
CY657_RS08910	COG1349	DNA-binding transcription factor activity
CY657_RS08915	COG0671	phosphoesterase, PA-phosphatase related
CY657_RS08925	COG2814	Major facilitator Superfamily
CY657_RS08930	COG0561	phosphatase activity
CY657_RS08935	COG0738	Major facilitator superfamily
CY657_RS08940	COG3226	Transcriptional regulator
CY657_RS08965	COG0778	Nitroreductase
CY657_RS08980	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CY657_RS08985	COG3842	ATPase activity
CY657_RS08990	COG1176	ABC-type spermidine putrescine transport system, permease component I
CY657_RS08995	COG1177	transmembrane transport
CY657_RS09010	COG0745	RESPONSE REGULATOR receiver
CY657_RS09015	COG5002	protein histidine kinase activity
CY657_RS09020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS09025	COG4160	amino acid transport
CY657_RS09030	COG4215	(ABC) transporter
CY657_RS09035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS09040	COG1126	abc transporter atp-binding protein
CY657_RS09050	COG3706	GGDEF domain
CY657_RS09050	COG5001	Diguanylate cyclase
CY657_RS09050	COG2203	Gaf domain
CY657_RS09050	COG4251	negative regulation of phosphorylation
CY657_RS09055	COG3023	N-Acetylmuramoyl-L-alanine amidase
CY657_RS09060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY657_RS09065	COG0702	epimerase
CY657_RS09070	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CY657_RS09075	COG0028	Belongs to the TPP enzyme family
CY657_RS09085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS09095	COG2431	L-lysine efflux transmembrane transporter activity
CY657_RS09105	COG3593	DNA synthesis involved in DNA repair
CY657_RS09110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS09120	COG1278	Cold shock
CY657_RS09130	COG0542	response to heat
CY657_RS09145	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CY657_RS09150	COG4988	ABC transporter
CY657_RS09155	COG0492	ferredoxin-NADP+ reductase activity
CY657_RS09165	COG1674	ftsk spoiiie
CY657_RS09165	COG1178	ABC-type Fe3 transport system permease component
CY657_RS09175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CY657_RS09185	COG0243	molybdopterin cofactor binding
CY657_RS09190	COG0437	4 iron, 4 sulfur cluster binding
CY657_RS09195	COG3302	dmso reductase anchor subunit
CY657_RS09205	COG0477	Major facilitator Superfamily
CY657_RS09210	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CY657_RS09215	COG1882	Formate acetyltransferase
CY657_RS09220	COG2116	formate transmembrane transporter activity
CY657_RS09225	COG1944	ATP diphosphatase activity
CY657_RS09230	COG2323	membrane
CY657_RS09250	COG0539	negative regulation of cytoplasmic translation
CY657_RS09260	COG2333	competence protein COMEC
CY657_RS09260	COG0658	competence protein
CY657_RS09275	COG3214	Protein conserved in bacteria
CY657_RS09290	COG3173	Aminoglycoside phosphotransferase
CY657_RS09295	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CY657_RS09300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CY657_RS09310	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CY657_RS09320	COG2989	Protein conserved in bacteria
CY657_RS09325	COG3108	Peptidase M15
CY657_RS09330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY657_RS09335	COG1448	Aminotransferase
CY657_RS09340	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CY657_RS09350	COG1522	sequence-specific DNA binding
CY657_RS09360	COG0814	amino acid
CY657_RS09370	COG1473	amidohydrolase
CY657_RS09380	COG0308	aminopeptidase N
CY657_RS09390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS09395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS09400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY657_RS09405	COG0431	NADPH-dependent FMN reductase
CY657_RS09420	COG0633	Ferredoxin
CY657_RS09420	COG3217	Mosc domain protein beta barrel domain protein
CY657_RS09430	COG0488	(ABC) transporter
CY657_RS09435	COG2995	paraquat-inducible protein a
CY657_RS09440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CY657_RS09440	COG3008	intermembrane lipid transfer
CY657_RS09445	COG3009	Protein conserved in bacteria
CY657_RS09450	COG3130	regulation of translation
CY657_RS09460	COG1067	ATP-dependent peptidase activity
CY657_RS09485	COG3070	regulator of competence-specific genes
CY657_RS09490	COG1289	transmembrane transporter activity
CY657_RS09495	COG3304	Inner membrane component domain
CY657_RS09500	COG0210	DNA helicase
CY657_RS09510	COG1832	CoA-binding protein
CY657_RS09525	COG1881	PFAM PEBP family protein
CY657_RS09530	COG2207	Transcriptional regulator
CY657_RS09545	COG0670	Belongs to the BI1 family
CY657_RS09560	COG2200	EAL domain
CY657_RS09565	COG2200	EAL domain
CY657_RS09575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS09580	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS09585	COG4638	Rieske (2fe-2S)
CY657_RS09590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CY657_RS09595	COG0473	3-isopropylmalate dehydrogenase activity
CY657_RS09605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY657_RS09610	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS09615	COG1917	Cupin 2, conserved barrel domain protein
CY657_RS09615	COG1396	sequence-specific DNA binding
CY657_RS09620	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CY657_RS09625	COG0174	glutamine synthetase
CY657_RS09635	COG0531	amino acid
CY657_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS09675	COG3729	General stress protein
CY657_RS09685	COG2233	PERMEase
CY657_RS09720	COG1309	transcriptional regulator
CY657_RS09735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CY657_RS09745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY657_RS09765	COG1702	phosphate starvation-inducible protein PhoH
CY657_RS09775	COG1335	isochorismatase
CY657_RS09785	COG0583	DNA-binding transcription factor activity
CY657_RS09790	COG1309	transcriptional regulator
CY657_RS09830	COG3381	protein complex oligomerization
CY657_RS09865	COG5645	(Lipo)protein
CY657_RS09880	COG1560	Kdo2-lipid A biosynthetic process
CY657_RS09930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY657_RS09950	COG2814	Major facilitator Superfamily
CY657_RS09955	COG0583	DNA-binding transcription factor activity
CY657_RS09960	COG1530	ribonuclease E activity
CY657_RS09975	COG1399	metal-binding, possibly nucleic acid-binding protein
CY657_RS09995	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CY657_RS10010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CY657_RS10015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CY657_RS10020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CY657_RS10030	COG0470	DNA polymerase III
CY657_RS10035	COG0084	hydrolase, TatD family'
CY657_RS10045	COG0537	adenosine 5'-monophosphoramidase activity
CY657_RS10050	COG5633	Lipoprotein
CY657_RS10075	COG1252	NADH dehydrogenase
CY657_RS10080	COG3134	Outer membrane lipoprotein
CY657_RS10090	COG1309	transcriptional regulator
CY657_RS10100	COG1376	ErfK ybiS ycfS ynhG family protein
CY657_RS10100	COG1388	LysM domain
CY657_RS10105	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CY657_RS10110	COG4591	ABC-type transport system involved in lipoprotein release permease component
CY657_RS10120	COG4591	ABC-type transport system involved in lipoprotein release permease component
CY657_RS10130	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CY657_RS10140	COG2390	Transcriptional regulator
CY657_RS10155	COG3395	kinase activity
CY657_RS10170	COG0698	ribose 5-phosphate isomerase
CY657_RS10175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CY657_RS10180	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CY657_RS10185	COG0318	PFAM AMP-dependent synthetase and ligase
CY657_RS10200	COG1177	transmembrane transport
CY657_RS10225	COG1943	Transposase
CY657_RS10230	COG2850	peptidyl-arginine hydroxylation
CY657_RS10235	COG2205	protein histidine kinase activity
CY657_RS10255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CY657_RS10275	COG1187	pseudouridine synthase activity
CY657_RS10280	COG0538	isocitrate dehydrogenase activity
CY657_RS10285	COG0582	viral genome integration into host DNA
CY657_RS10300	COG3706	GGDEF domain
CY657_RS10305	COG3300	MHYT domain
CY657_RS10305	COG5001	Diguanylate cyclase
CY657_RS10315	COG0538	isocitrate dehydrogenase activity
CY657_RS10320	COG0640	Transcriptional regulator
CY657_RS10345	COG3813	Protein conserved in bacteria
CY657_RS10350	COG1063	alcohol dehydrogenase
CY657_RS10355	COG3729	General stress protein
CY657_RS10360	COG3685	Protein conserved in bacteria
CY657_RS10365	COG3685	Protein conserved in bacteria
CY657_RS10375	COG1271	oxidase subunit
CY657_RS10380	COG1294	oxidase, subunit
CY657_RS10405	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CY657_RS10410	COG0583	DNA-binding transcription factor activity
CY657_RS10415	COG3706	GGDEF domain
CY657_RS10420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CY657_RS10430	COG1560	Kdo2-lipid A biosynthetic process
CY657_RS10440	COG3182	Iron-regulated membrane protein
CY657_RS10460	COG2203	Gaf domain
CY657_RS10460	COG2199	diguanylate cyclase activity
CY657_RS10465	COG3042	response to heat
CY657_RS10470	COG3189	MarR family transcriptional regulator
CY657_RS10475	COG1683	Conserved Protein
CY657_RS10480	COG0504	CTP synthase activity
CY657_RS10485	COG2807	transmembrane transport
CY657_RS10490	COG2207	Transcriptional regulator
CY657_RS10500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CY657_RS10505	COG0859	PFAM glycosyl transferase family 9
CY657_RS10515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CY657_RS10520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CY657_RS10525	COG0583	DNA-binding transcription factor activity
CY657_RS10530	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS10550	COG0386	Belongs to the glutathione peroxidase family
CY657_RS10565	COG2766	serine protein kinase
CY657_RS10570	COG3713	MltA-interacting MipA family protein
CY657_RS10575	COG0656	L-ascorbic acid biosynthetic process
CY657_RS10595	COG3139	Protein of unknown function (DUF1315)
CY657_RS10610	COG1335	isochorismatase
CY657_RS10615	COG0252	asparaginase activity
CY657_RS10620	COG0616	signal peptide processing
CY657_RS10625	COG0778	Nitroreductase
CY657_RS10640	COG0709	Synthesizes selenophosphate from selenide and ATP
CY657_RS10645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CY657_RS10650	COG3321	synthase
CY657_RS10650	COG0604	alcohol dehydrogenase
CY657_RS10650	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS10655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CY657_RS10660	COG0494	nUDIX hydrolase
CY657_RS10665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CY657_RS10670	COG2897	thiosulfate sulfurtransferase activity
CY657_RS10675	COG4136	ATPase activity
CY657_RS10680	COG4135	transport system, permease component
CY657_RS10685	COG4134	Bacterial extracellular solute-binding protein
CY657_RS10690	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS10695	COG0398	Pfam SNARE associated Golgi protein
CY657_RS10700	COG0398	Pfam SNARE associated Golgi protein
CY657_RS10705	COG0708	Exodeoxyribonuclease III
CY657_RS10715	COG3138	arginine N-succinyltransferase
CY657_RS10725	COG3724	N-succinylarginine dihydrolase activity
CY657_RS10735	COG3678	ATP-independent chaperone mediated protein folding
CY657_RS10740	COG0322	excinuclease ABC activity
CY657_RS10750	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CY657_RS10755	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS10760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS10765	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS10770	COG1917	Cupin 2, conserved barrel domain protein
CY657_RS10770	COG2169	Transcriptional regulator
CY657_RS10775	COG1486	melibiose metabolic process
CY657_RS10785	COG0753	catalase activity
CY657_RS10795	COG1823	symporter activity
CY657_RS10800	COG1988	membrane-bound metal-dependent
CY657_RS10805	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS10810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS10840	COG0727	PFAM Uncharacterised protein family (UPF0153)
CY657_RS10845	COG3047	cAMP biosynthetic process
CY657_RS10855	COG4774	siderophore transport
CY657_RS10890	COG0135	phosphoribosylanthranilate isomerase activity
CY657_RS10890	COG0134	indole-3-glycerol-phosphate synthase activity
CY657_RS10895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CY657_RS10895	COG0512	Glutamine amidotransferase of anthranilate synthase
CY657_RS10900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CY657_RS10910	COG0009	L-threonylcarbamoyladenylate synthase
CY657_RS10920	COG0583	DNA-binding transcription factor activity
CY657_RS10930	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CY657_RS10935	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS10945	COG0616	signal peptide processing
CY657_RS10970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CY657_RS10980	COG0671	phosphoesterase, PA-phosphatase related
CY657_RS10985	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CY657_RS10990	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CY657_RS11000	COG0023	Translation Initiation Factor
CY657_RS11010	COG1349	DNA-binding transcription factor activity
CY657_RS11025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS11025	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS11030	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CY657_RS11040	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CY657_RS11055	COG4171	peptide transport system, permease
CY657_RS11090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY657_RS11130	COG1484	DNA-dependent DNA replication
CY657_RS11185	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CY657_RS11190	COG0484	heat shock protein binding
CY657_RS11245	COG5484	DNA packaging
CY657_RS11245	COG3728	DNA packaging
CY657_RS11330	COG1196	nuclear chromosome segregation
CY657_RS11390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CY657_RS11395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CY657_RS11410	COG2135	peptidase activity
CY657_RS11425	COG0702	epimerase
CY657_RS11440	COG1473	amidohydrolase
CY657_RS11450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CY657_RS11455	COG1842	Phage shock protein A
CY657_RS11465	COG1983	PspC domain protein
CY657_RS11475	COG3106	COG3106 Predicted ATPase
CY657_RS11485	COG0583	DNA-binding transcription factor activity
CY657_RS11490	COG1486	melibiose metabolic process
CY657_RS11500	COG3180	Ammonia monooxygenase
CY657_RS11505	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CY657_RS11510	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS11515	COG2866	Carboxypeptidase
CY657_RS11520	COG4166	transmembrane transport
CY657_RS11550	COG0656	L-ascorbic acid biosynthetic process
CY657_RS11570	COG0583	DNA-binding transcription factor activity
CY657_RS11575	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS11580	COG1078	dGTPase activity
CY657_RS11585	COG0693	protein deglycase activity
CY657_RS11610	COG2885	chlorophyll binding
CY657_RS11705	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS11710	COG1309	transcriptional regulator
CY657_RS11715	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS11735	COG0583	DNA-binding transcription factor activity
CY657_RS11760	COG0604	alcohol dehydrogenase
CY657_RS11765	COG0436	Aminotransferase
CY657_RS11780	COG2011	ABC-type metal ion transport system permease component
CY657_RS11795	COG0673	inositol 2-dehydrogenase activity
CY657_RS11800	COG1349	DNA-binding transcription factor activity
CY657_RS11815	COG0513	Belongs to the DEAD box helicase family
CY657_RS11825	COG0589	response to stress
CY657_RS11835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CY657_RS11840	COG0674	pyruvate-flavodoxin oxidoreductase activity
CY657_RS11840	COG1013	pyruvate-flavodoxin oxidoreductase activity
CY657_RS11840	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CY657_RS11840	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY657_RS11850	COG3042	response to heat
CY657_RS11855	COG3187	Heat shock protein
CY657_RS11860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CY657_RS11865	COG0586	Pfam SNARE associated Golgi protein
CY657_RS11870	COG2911	Protein conserved in bacteria
CY657_RS11880	COG3784	Protein of unknown function (DUF1318)
CY657_RS11885	COG2207	Transcriptional regulator
CY657_RS11890	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS11910	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS11910	COG2030	dehydratase
CY657_RS11915	COG3396	Phenylacetate-CoA oxygenase
CY657_RS11920	COG3460	Phenylacetate-CoA oxygenase
CY657_RS11925	COG3396	Phenylacetate-CoA oxygenase
CY657_RS11930	COG2151	metal-sulfur cluster biosynthetic enzyme
CY657_RS11935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS11940	COG1024	Enoyl-CoA hydratase
CY657_RS11945	COG1024	Enoyl-CoA hydratase
CY657_RS11950	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY657_RS11955	COG2050	protein possibly involved in aromatic compounds catabolism
CY657_RS11960	COG0183	Belongs to the thiolase family
CY657_RS11965	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CY657_RS11970	COG3327	negative regulation of DNA-templated transcription, initiation
CY657_RS11975	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CY657_RS11990	COG1643	Atp-dependent helicase
CY657_RS11995	COG4122	O-methyltransferase activity
CY657_RS12020	COG0583	DNA-binding transcription factor activity
CY657_RS12025	COG0667	Aldo Keto reductase
CY657_RS12030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CY657_RS12035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CY657_RS12040	COG3138	arginine N-succinyltransferase
CY657_RS12045	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS12050	COG3724	N-succinylarginine dihydrolase activity
CY657_RS12055	COG2988	succinylglutamate desuccinylase activity
CY657_RS12060	COG1113	amino acid transport
CY657_RS12065	COG0477	Major facilitator Superfamily
CY657_RS12070	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CY657_RS12075	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS12080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CY657_RS12085	COG0401	homolog of Blt101
CY657_RS12090	COG5562	phage envelope protein
CY657_RS12095	COG0425	Belongs to the sulfur carrier protein TusA family
CY657_RS12100	COG2391	methyltransferase activity
CY657_RS12125	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CY657_RS12130	COG1263	PTS System
CY657_RS12130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS12135	COG1609	Transcriptional regulator
CY657_RS12140	COG5339	Protein conserved in bacteria
CY657_RS12145	COG1482	cell wall glycoprotein biosynthetic process
CY657_RS12150	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CY657_RS12150	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CY657_RS12155	COG0114	fumarate hydratase activity
CY657_RS12165	COG2205	protein histidine kinase activity
CY657_RS12175	COG0745	RESPONSE REGULATOR receiver
CY657_RS12180	COG3136	membrane protein required for alginate biosynthesis
CY657_RS12190	COG0531	amino acid
CY657_RS12210	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CY657_RS12215	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CY657_RS12230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CY657_RS12245	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CY657_RS12250	COG1473	amidohydrolase
CY657_RS12260	COG0583	DNA-binding transcription factor activity
CY657_RS12265	COG2840	Smr protein MutS2
CY657_RS12270	COG1414	Transcriptional regulator
CY657_RS12280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CY657_RS12285	COG0183	Belongs to the thiolase family
CY657_RS12295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CY657_RS12300	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS12310	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CY657_RS12310	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CY657_RS12330	COG4565	transcriptional regulatory protein
CY657_RS12335	COG3290	protein histidine kinase activity
CY657_RS12360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CY657_RS12370	COG0679	Auxin Efflux Carrier
CY657_RS12400	COG0628	permease
CY657_RS12420	COG3591	Belongs to the peptidase S1B family
CY657_RS12430	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CY657_RS12435	COG2814	Major facilitator Superfamily
CY657_RS12440	COG0583	DNA-binding transcription factor activity
CY657_RS12445	COG1940	carbohydrate kinase activity
CY657_RS12450	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CY657_RS12465	COG3302	dmso reductase anchor subunit
CY657_RS12470	COG0437	4 iron, 4 sulfur cluster binding
CY657_RS12475	COG0243	molybdopterin cofactor binding
CY657_RS12490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY657_RS12505	COG2271	Major facilitator Superfamily
CY657_RS12510	COG0246	Mannitol dehydrogenase
CY657_RS12515	COG0589	response to stress
CY657_RS12520	COG1802	Transcriptional regulator
CY657_RS12525	COG4221	oxidoreductase activity
CY657_RS12540	COG2207	Transcriptional regulator
CY657_RS12545	COG2135	peptidase activity
CY657_RS12570	COG0071	Belongs to the small heat shock protein (HSP20) family
CY657_RS12575	COG1546	Belongs to the CinA family
CY657_RS12580	COG2200	EAL domain
CY657_RS12600	COG3708	Transcriptional regulator
CY657_RS12600	COG2207	Transcriptional regulator
CY657_RS12605	COG2610	gluconate transmembrane transporter activity
CY657_RS12610	COG3622	Belongs to the hyi family
CY657_RS12615	COG0235	Class ii aldolase
CY657_RS12620	COG3395	kinase activity
CY657_RS12625	COG2084	Dehydrogenase
CY657_RS12630	COG1349	DNA-binding transcription factor activity
CY657_RS12645	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CY657_RS12650	COG2223	nitrite transmembrane transporter activity
CY657_RS12685	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CY657_RS12690	COG0683	leucine binding
CY657_RS12720	COG2814	Major facilitator Superfamily
CY657_RS12725	COG0697	spore germination
CY657_RS12735	COG4977	sequence-specific DNA binding
CY657_RS12760	COG2271	Major facilitator Superfamily
CY657_RS12765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY657_RS12770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CY657_RS12780	COG3395	kinase activity
CY657_RS12785	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CY657_RS12790	COG1349	DNA-binding transcription factor activity
CY657_RS12795	COG0039	L-malate dehydrogenase activity
CY657_RS12805	COG0583	DNA-binding transcription factor activity
CY657_RS12810	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS12825	COG2199	diguanylate cyclase activity
CY657_RS12910	COG0477	Major facilitator Superfamily
CY657_RS12920	COG2070	2-Nitropropane dioxygenase
CY657_RS12925	COG2011	ABC-type metal ion transport system permease component
CY657_RS12945	COG4628	conserved protein (DUF2132)
CY657_RS12960	COG2207	Transcriptional regulator
CY657_RS12990	COG2233	PERMEase
CY657_RS12995	COG3195	allantoin biosynthetic process
CY657_RS12995	COG3648	Uricase
CY657_RS13000	COG2351	hydroxyisourate hydrolase activity
CY657_RS13005	COG1396	sequence-specific DNA binding
CY657_RS13010	COG3550	peptidyl-serine autophosphorylation
CY657_RS13015	COG1649	PFAM Uncharacterised BCR, COG1649
CY657_RS13025	COG3188	usher protein
CY657_RS13060	COG3300	MHYT domain
CY657_RS13060	COG5001	Diguanylate cyclase
CY657_RS13065	COG2819	hydrolase of the alpha beta superfamily
CY657_RS13075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS13075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS13080	COG2814	Major facilitator Superfamily
CY657_RS13090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS13090	COG1263	PTS System
CY657_RS13095	COG2186	Transcriptional regulator
CY657_RS13115	COG3835	regulator
CY657_RS13120	COG1929	Belongs to the glycerate kinase type-1 family
CY657_RS13165	COG0738	Major facilitator superfamily
CY657_RS13170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS13175	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CY657_RS13180	COG1349	DNA-binding transcription factor activity
CY657_RS13195	COG1349	DNA-binding transcription factor activity
CY657_RS13210	COG4977	sequence-specific DNA binding
CY657_RS13235	COG0667	Aldo Keto reductase
CY657_RS13240	COG3386	PFAM SMP-30 Gluconolaconase
CY657_RS13245	COG0667	Aldo Keto reductase
CY657_RS13250	COG0667	Aldo Keto reductase
CY657_RS13260	COG0456	acetyltransferase
CY657_RS13260	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CY657_RS13285	COG1652	LysM domain
CY657_RS13315	COG1609	Transcriptional regulator
CY657_RS13325	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS13350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY657_RS13355	COG0583	DNA-binding transcription factor activity
CY657_RS13365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS13370	COG1609	Transcriptional regulator
CY657_RS13380	COG2223	nitrite transmembrane transporter activity
CY657_RS13420	COG0477	Major facilitator Superfamily
CY657_RS13425	COG4529	Protein conserved in bacteria
CY657_RS13430	COG1902	pentaerythritol trinitrate reductase activity
CY657_RS13440	COG0583	DNA-binding transcription factor activity
CY657_RS13445	COG2070	2-Nitropropane dioxygenase
CY657_RS13455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CY657_RS13465	COG0765	amino acid transport
CY657_RS13530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CY657_RS13550	COG2207	Transcriptional regulator
CY657_RS13565	COG0596	Alpha beta hydrolase
CY657_RS13600	COG1953	Uracil, thiamine, allantoin
CY657_RS13605	COG0402	S-adenosylhomocysteine deaminase activity
CY657_RS13610	COG3706	GGDEF domain
CY657_RS13615	COG1609	Transcriptional regulator
CY657_RS13625	COG0673	inositol 2-dehydrogenase activity
CY657_RS13635	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CY657_RS13640	COG1116	anion transmembrane transporter activity
CY657_RS13645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS13650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY657_RS13655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CY657_RS13660	COG0076	glutamate decarboxylase activity
CY657_RS13675	COG2205	protein histidine kinase activity
CY657_RS13685	COG0596	Alpha beta hydrolase
CY657_RS13725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CY657_RS13725	COG0519	Catalyzes the synthesis of GMP from XMP
CY657_RS13745	COG0583	DNA-binding transcription factor activity
CY657_RS13755	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CY657_RS13760	COG1285	pathogenesis
CY657_RS13770	COG2814	Major facilitator Superfamily
CY657_RS13775	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS13780	COG0583	DNA-binding transcription factor activity
CY657_RS13785	COG0243	molybdopterin cofactor binding
CY657_RS13790	COG3781	membrane
CY657_RS13815	COG1764	response to oxidative stress
CY657_RS13820	COG3111	PFAM Bacterial OB fold (BOF) protein
CY657_RS13830	COG2323	membrane
CY657_RS13840	COG0366	Alpha amylase catalytic
CY657_RS13850	COG3685	Protein conserved in bacteria
CY657_RS13870	COG3729	General stress protein
CY657_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS13915	COG0488	(ABC) transporter
CY657_RS13930	COG1064	alcohol dehydrogenase
CY657_RS13935	COG0747	negative chemotaxis
CY657_RS13945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS13955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS13965	COG2814	Major facilitator Superfamily
CY657_RS13975	COG2326	polyphosphate kinase activity
CY657_RS13990	COG2864	formate dehydrogenase
CY657_RS13995	COG0437	4 iron, 4 sulfur cluster binding
CY657_RS14020	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CY657_RS14030	COG3485	protocatechuate 3,4-dioxygenase
CY657_RS14035	COG4829	muconolactone delta-isomerase
CY657_RS14040	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS14045	COG1414	Transcriptional regulator
CY657_RS14065	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CY657_RS14070	COG1140	nitrate reductase beta subunit
CY657_RS14075	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CY657_RS14080	COG2181	nitrate reductase activity
CY657_RS14085	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CY657_RS14090	COG1178	ABC-type Fe3 transport system permease component
CY657_RS14095	COG1840	ABC-type Fe3 transport system, periplasmic component
CY657_RS14100	COG3842	ATPase activity
CY657_RS14105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CY657_RS14120	COG0625	glutathione transferase activity
CY657_RS14125	COG1609	Transcriptional regulator
CY657_RS14135	COG2271	Major facilitator Superfamily
CY657_RS14145	COG1126	abc transporter atp-binding protein
CY657_RS14150	COG0765	amino acid transport
CY657_RS14160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS14165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS14170	COG1473	amidohydrolase
CY657_RS14175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS14180	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CY657_RS14205	COG4772	TonB-dependent receptor
CY657_RS14210	COG1228	amidohydrolase
CY657_RS14215	COG3691	Protein conserved in bacteria
CY657_RS14230	COG2130	NADP-dependent
CY657_RS14240	COG1247	-acetyltransferase
CY657_RS14245	COG3238	Protein conserved in bacteria
CY657_RS14255	COG0747	negative chemotaxis
CY657_RS14260	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS14295	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS14300	COG1177	transmembrane transport
CY657_RS14305	COG1176	ABC-type spermidine putrescine transport system, permease component I
CY657_RS14310	COG3842	ATPase activity
CY657_RS14315	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CY657_RS14320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY657_RS14325	COG1271	oxidase subunit
CY657_RS14330	COG1294	oxidase, subunit
CY657_RS14350	COG0826	peptidase U32
CY657_RS14360	COG1396	sequence-specific DNA binding
CY657_RS14365	COG3135	benzoate transporter
CY657_RS14370	COG3708	Transcriptional regulator
CY657_RS14370	COG2207	Transcriptional regulator
CY657_RS14385	COG0500	methyltransferase
CY657_RS14390	COG1275	C4-dicarboxylate transporter malic acid transport protein
CY657_RS14395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CY657_RS14400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY657_RS14415	COG2272	Belongs to the type-B carboxylesterase lipase family
CY657_RS14420	COG5383	Protein conserved in bacteria
CY657_RS14425	COG3485	protocatechuate 3,4-dioxygenase
CY657_RS14430	COG3485	protocatechuate 3,4-dioxygenase
CY657_RS14435	COG0583	DNA-binding transcription factor activity
CY657_RS14455	COG3038	cytochrome b561
CY657_RS14475	COG2814	Major facilitator Superfamily
CY657_RS14485	COG0673	inositol 2-dehydrogenase activity
CY657_RS14495	COG2723	6-phospho-beta-galactosidase activity
CY657_RS14530	COG4659	FMN binding
CY657_RS14540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CY657_RS14555	COG0625	glutathione transferase activity
CY657_RS14560	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CY657_RS14575	COG3895	Periplasmic Protein
CY657_RS14590	COG3706	GGDEF domain
CY657_RS14605	COG1566	PFAM secretion protein HlyD family protein
CY657_RS14610	COG1289	transmembrane transporter activity
CY657_RS14615	COG2032	superoxide dismutase activity
CY657_RS14620	COG4989	oxidoreductase activity
CY657_RS14625	COG3313	Fe-S protein
CY657_RS14630	COG1309	transcriptional regulator
CY657_RS14635	COG1902	pentaerythritol trinitrate reductase activity
CY657_RS14640	COG0346	lactoylglutathione lyase activity
CY657_RS14650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CY657_RS14655	COG0791	NLP P60 protein
CY657_RS14670	COG2814	Major facilitator Superfamily
CY657_RS14685	COG0583	DNA-binding transcription factor activity
CY657_RS14690	COG2814	Major facilitator Superfamily
CY657_RS14695	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CY657_RS14700	COG0307	riboflavin synthase, alpha
CY657_RS14760	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CY657_RS14790	COG1349	DNA-binding transcription factor activity
CY657_RS14795	COG0346	lactoylglutathione lyase activity
CY657_RS14820	COG0444	Belongs to the ABC transporter superfamily
CY657_RS14825	COG4608	Belongs to the ABC transporter superfamily
CY657_RS14870	COG0583	DNA-binding transcription factor activity
CY657_RS14880	COG0402	S-adenosylhomocysteine deaminase activity
CY657_RS14905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS14910	COG0277	FAD linked oxidase domain protein
CY657_RS14930	COG0583	DNA-binding transcription factor activity
CY657_RS14940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CY657_RS14950	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY657_RS14955	COG2610	gluconate transmembrane transporter activity
CY657_RS14960	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS14995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS15010	COG0745	RESPONSE REGULATOR receiver
CY657_RS15015	COG5002	protein histidine kinase activity
CY657_RS15015	COG3850	Histidine kinase
CY657_RS15035	COG4235	cytochrome complex assembly
CY657_RS15035	COG3088	subunit of a heme lyase
CY657_RS15045	COG1138	Cytochrome C-type biogenesis protein
CY657_RS15060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CY657_RS15065	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CY657_RS15070	COG4133	protoheme IX ABC transporter activity
CY657_RS15100	COG3157	Type VI secretion system effector, Hcp
CY657_RS15105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY657_RS15110	COG1518	maintenance of DNA repeat elements
CY657_RS15120	COG1857	crispr-associated protein
CY657_RS15155	COG1175	transmembrane transport
CY657_RS15170	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CY657_RS15175	COG3383	formate dehydrogenase (NAD+) activity
CY657_RS15180	COG1473	amidohydrolase
CY657_RS15210	COG1126	abc transporter atp-binding protein
CY657_RS15215	COG0765	amino acid transport
CY657_RS15235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS15240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS15245	COG1120	ATPase activity
CY657_RS15250	COG4774	siderophore transport
CY657_RS15255	COG1116	anion transmembrane transporter activity
CY657_RS15260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY657_RS15280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS15285	COG0583	DNA-binding transcription factor activity
CY657_RS15305	COG2814	Major facilitator Superfamily
CY657_RS15340	COG1414	Transcriptional regulator
CY657_RS15345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY657_RS15350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS15355	COG1120	ATPase activity
CY657_RS15365	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CY657_RS15370	COG2271	Major facilitator Superfamily
CY657_RS15375	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CY657_RS15375	COG1082	Xylose isomerase domain protein TIM barrel
CY657_RS15380	COG1309	transcriptional regulator
CY657_RS15405	COG1376	ErfK ybiS ycfS ynhG family protein
CY657_RS15420	COG0719	Fe-S assembly protein
CY657_RS15425	COG0396	ATPase activity
CY657_RS15430	COG0719	Fe-S assembly protein
CY657_RS15435	COG0316	Belongs to the HesB IscA family
CY657_RS15450	COG1309	transcriptional regulator
CY657_RS15455	COG1304	FMN binding
CY657_RS15480	COG0583	DNA-binding transcription factor activity
CY657_RS15490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS15495	COG1120	ATPase activity
CY657_RS15525	COG2261	transglycosylase associated protein
CY657_RS15530	COG2050	protein possibly involved in aromatic compounds catabolism
CY657_RS15535	COG0247	lactate metabolic process
CY657_RS15535	COG0277	FAD linked oxidase domain protein
CY657_RS15540	COG0628	permease
CY657_RS15550	COG0574	Belongs to the PEP-utilizing enzyme family
CY657_RS15550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CY657_RS15560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CY657_RS15565	COG4256	Hemin uptake protein
CY657_RS15575	COG0791	NLP P60 protein
CY657_RS15585	COG0386	Belongs to the glutathione peroxidase family
CY657_RS15605	COG0583	DNA-binding transcription factor activity
CY657_RS15625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CY657_RS15625	COG0072	phenylalanine-tRNA ligase activity
CY657_RS15670	COG3137	Salt-induced outer membrane protein
CY657_RS15675	COG1105	Belongs to the carbohydrate kinase PfkB family
CY657_RS15685	COG3001	Fructosamine kinase
CY657_RS15695	COG2350	Protein conserved in bacteria
CY657_RS15705	COG2353	YceI-like domain
CY657_RS15725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CY657_RS15735	COG0444	Belongs to the ABC transporter superfamily
CY657_RS15740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS15745	COG0601	transmembrane transport
CY657_RS15750	COG4166	transmembrane transport
CY657_RS15755	COG2095	MarC family integral membrane protein
CY657_RS15765	COG1454	alcohol dehydrogenase
CY657_RS15765	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS15770	COG1435	thymidine kinase activity
CY657_RS15775	COG2916	Histone family protein nucleoid-structuring protein H-NS
CY657_RS15780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CY657_RS15785	COG0745	RESPONSE REGULATOR receiver
CY657_RS15790	COG1752	Esterase of the alpha-beta hydrolase superfamily
CY657_RS15800	COG0788	formyltetrahydrofolate deformylase activity
CY657_RS15830	COG1522	sequence-specific DNA binding
CY657_RS15840	COG2181	nitrate reductase activity
CY657_RS15845	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CY657_RS15850	COG1140	nitrate reductase beta subunit
CY657_RS15855	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CY657_RS15860	COG2223	nitrite transmembrane transporter activity
CY657_RS15865	COG3850	Histidine kinase
CY657_RS15870	COG2197	response regulator
CY657_RS15875	COG4932	domain protein
CY657_RS15880	COG0243	molybdopterin cofactor binding
CY657_RS15885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CY657_RS15885	COG2146	nitrite reductase [NAD(P)H] activity
CY657_RS15890	COG1116	anion transmembrane transporter activity
CY657_RS15900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY657_RS15905	COG3707	response regulator
CY657_RS15910	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CY657_RS15920	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CY657_RS15925	COG4572	Cation transport regulator
CY657_RS15930	COG0387	Pfam Sodium calcium exchanger
CY657_RS15950	COG2890	protein-(glutamine-N5) methyltransferase activity
CY657_RS15980	COG0659	secondary active sulfate transmembrane transporter activity
CY657_RS16000	COG0012	GTP binding
CY657_RS16065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CY657_RS16075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CY657_RS16135	COG2885	chlorophyll binding
CY657_RS16160	COG3122	Protein conserved in bacteria
CY657_RS16175	COG0583	DNA-binding transcription factor activity
CY657_RS16205	COG0583	DNA-binding transcription factor activity
CY657_RS16235	COG1882	Formate acetyltransferase
CY657_RS16250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CY657_RS16255	COG0583	DNA-binding transcription factor activity
CY657_RS16300	COG2308	Evidence 4 Homologs of previously reported genes of
CY657_RS16325	COG1619	proteins homologs of microcin C7 resistance protein MccF
CY657_RS16345	COG2719	SpoVR family
CY657_RS16375	COG0179	Fumarylacetoacetate (FAA) hydrolase
CY657_RS16390	COG2894	cell division
CY657_RS16400	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CY657_RS16410	COG3065	identical protein binding
CY657_RS16420	COG1199	ATP-dependent helicase activity
CY657_RS16425	COG0251	oxidation-reduction process
CY657_RS16445	COG1760	l-serine dehydratase
CY657_RS16450	COG2200	EAL domain
CY657_RS16455	COG1253	flavin adenine dinucleotide binding
CY657_RS16460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS16460	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS16465	COG3715	PTS system
CY657_RS16470	COG3716	PTS system mannose fructose sorbose family IID component
CY657_RS16485	COG2226	methyltransferase
CY657_RS16490	COG0768	penicillin binding
CY657_RS16530	COG1414	Transcriptional regulator
CY657_RS16535	COG2814	Major facilitator Superfamily
CY657_RS16555	COG1956	GAF domain-containing protein
CY657_RS16560	COG2995	paraquat-inducible protein a
CY657_RS16565	COG3008	intermembrane lipid transfer
CY657_RS16590	COG2990	Protein conserved in bacteria
CY657_RS16610	COG1276	copper resistance
CY657_RS16615	COG2372	response to copper ion
CY657_RS16625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY657_RS16630	COG1770	oligopeptidase
CY657_RS16635	COG2979	Protein of unknown function (DUF533)
CY657_RS16640	COG3141	response to X-ray
CY657_RS16650	COG0800	Aldolase
CY657_RS16655	COG0129	dihydroxy-acid dehydratase activity
CY657_RS16660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CY657_RS16675	COG1737	Transcriptional regulator
CY657_RS16685	COG1560	Kdo2-lipid A biosynthetic process
CY657_RS16690	COG0739	heme binding
CY657_RS16695	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CY657_RS16705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY657_RS16730	COG0494	nUDIX hydrolase
CY657_RS16740	COG1335	isochorismatase
CY657_RS16745	COG1801	Protein of unknown function DUF72
CY657_RS16750	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CY657_RS16770	COG3102	Protein conserved in bacteria
CY657_RS16780	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CY657_RS16805	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY657_RS16815	COG1879	ABC-type sugar transport system periplasmic component
CY657_RS16825	COG1528	Iron-storage protein
CY657_RS16835	COG2211	Major facilitator Superfamily
CY657_RS16845	COG0477	Major facilitator Superfamily
CY657_RS16860	COG1528	Iron-storage protein
CY657_RS16870	COG0814	amino acid
CY657_RS16875	COG3012	SEC-C Motif Domain Protein
CY657_RS16875	COG3318	Belongs to the UPF0149 family
CY657_RS16915	COG2197	response regulator
CY657_RS16925	COG2197	response regulator
CY657_RS16930	COG1126	abc transporter atp-binding protein
CY657_RS16935	COG0765	amino acid transport
CY657_RS16945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS16950	COG0366	Alpha amylase catalytic
CY657_RS16980	COG2354	Protein conserved in bacteria
CY657_RS16985	COG0697	spore germination
CY657_RS16990	COG3727	T/G mismatch-specific endonuclease activity
CY657_RS16995	COG0270	DNA (cytosine-5-)-methyltransferase activity
CY657_RS17000	COG1418	mRNA catabolic process
CY657_RS17015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CY657_RS17065	COG0025	NhaP-type Na H and K H
CY657_RS17070	COG1309	transcriptional regulator
CY657_RS17075	COG0604	alcohol dehydrogenase
CY657_RS17095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CY657_RS17130	COG2916	Histone family protein nucleoid-structuring protein H-NS
CY657_RS17245	COG0582	viral genome integration into host DNA
CY657_RS17255	COG0534	Mate efflux family protein
CY657_RS17265	COG0582	viral genome integration into host DNA
CY657_RS17270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS17280	COG1959	2 iron, 2 sulfur cluster binding
CY657_RS17290	COG2207	Transcriptional regulator
CY657_RS17295	COG4221	oxidoreductase activity
CY657_RS17300	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS17360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CY657_RS17380	COG3451	type IV secretory pathway VirB4
CY657_RS17400	COG3736	Type IV secretory pathway, component VirB8
CY657_RS17405	COG3504	Conjugal transfer protein
CY657_RS17465	COG0758	DNA mediated transformation
CY657_RS17505	COG3423	Transcriptional regulator
CY657_RS17535	COG3706	GGDEF domain
CY657_RS17560	COG3615	Tellurite resistance protein tehB
CY657_RS17570	COG3300	MHYT domain
CY657_RS17570	COG5001	Diguanylate cyclase
CY657_RS17585	COG0477	Major facilitator Superfamily
CY657_RS17590	COG0095	Lipoate-protein ligase
CY657_RS17595	COG0583	DNA-binding transcription factor activity
CY657_RS17600	COG1942	4-Oxalocrotonate Tautomerase
CY657_RS17610	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CY657_RS17630	COG1289	transmembrane transporter activity
CY657_RS17645	COG2925	Exonuclease
CY657_RS17650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CY657_RS17655	COG0640	Transcriptional regulator
CY657_RS17660	COG0531	amino acid
CY657_RS17670	COG0583	DNA-binding transcription factor activity
CY657_RS17675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY657_RS17705	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CY657_RS17730	COG0463	Glycosyl transferase, family 2
CY657_RS17740	COG1442	glycosyl transferase family 8
CY657_RS17740	COG1216	Glycosyl transferase, family 2
CY657_RS17745	COG0438	transferase activity, transferring glycosyl groups
CY657_RS17825	COG0297	glycogen (starch) synthase activity
CY657_RS17830	COG1051	belongs to the nudix hydrolase family
CY657_RS17835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY657_RS17840	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CY657_RS17865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CY657_RS17900	COG1253	flavin adenine dinucleotide binding
CY657_RS17905	COG2982	Protein involved in outer membrane biogenesis
CY657_RS17920	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CY657_RS17925	COG0443	Heat shock 70 kDa protein
CY657_RS17930	COG5002	protein histidine kinase activity
CY657_RS17950	COG1301	dicarboxylic acid transport
CY657_RS17975	COG2205	protein histidine kinase activity
CY657_RS17980	COG0745	RESPONSE REGULATOR receiver
CY657_RS17985	COG0826	peptidase U32
CY657_RS17995	COG4608	Belongs to the ABC transporter superfamily
CY657_RS18000	COG0444	Belongs to the ABC transporter superfamily
CY657_RS18005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS18010	COG0601	transmembrane transport
CY657_RS18015	COG0747	negative chemotaxis
CY657_RS18020	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS18025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS18035	COG1070	Carbohydrate kinase
CY657_RS18060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CY657_RS18070	COG1830	Aldolase
CY657_RS18075	COG0351	phosphomethylpyrimidine kinase
CY657_RS18090	COG0583	DNA-binding transcription factor activity
CY657_RS18100	COG2252	PERMEase
CY657_RS18105	COG0583	DNA-binding transcription factor activity
CY657_RS18110	COG5455	response to cobalt ion
CY657_RS18130	COG4807	Protein conserved in bacteria
CY657_RS18140	COG3275	phosphorelay sensor kinase activity
CY657_RS18150	COG1174	glycine betaine transport
CY657_RS18155	COG1125	glycine betaine transport
CY657_RS18160	COG1174	glycine betaine transport
CY657_RS18165	COG1732	Glycine betaine
CY657_RS18170	COG1472	Belongs to the glycosyl hydrolase 3 family
CY657_RS18175	COG0277	FAD linked oxidase domain protein
CY657_RS18185	COG1686	Belongs to the peptidase S11 family
CY657_RS18195	COG0586	Pfam SNARE associated Golgi protein
CY657_RS18200	COG1538	Outer membrane efflux protein
CY657_RS18210	COG2723	6-phospho-beta-galactosidase activity
CY657_RS18225	COG3659	wide pore channel activity
CY657_RS18230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CY657_RS18240	COG1346	cytolysis
CY657_RS18250	COG2949	membrane
CY657_RS18260	COG1129	ABC transporter
CY657_RS18275	COG2311	Membrane
CY657_RS18290	COG4771	TonB-dependent receptor
CY657_RS18300	COG0833	amino acid
CY657_RS18305	COG0583	DNA-binding transcription factor activity
CY657_RS18310	COG2855	membrane
CY657_RS18320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CY657_RS18320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CY657_RS18320	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CY657_RS18325	COG1105	Belongs to the carbohydrate kinase PfkB family
CY657_RS18330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS18330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS18350	COG1312	Catalyzes the dehydration of D-mannonate
CY657_RS18355	COG0246	Mannitol dehydrogenase
CY657_RS18360	COG0523	cobalamin synthesis protein
CY657_RS18365	COG0671	phosphoesterase, PA-phosphatase related
CY657_RS18370	COG0791	NLP P60 protein
CY657_RS18375	COG2200	EAL domain
CY657_RS18380	COG4166	transmembrane transport
CY657_RS18385	COG4174	ABC transporter (Permease)
CY657_RS18390	COG4239	(ABC) transporter, permease
CY657_RS18395	COG4172	Belongs to the ABC transporter superfamily
CY657_RS18405	COG2814	Major facilitator Superfamily
CY657_RS18410	COG1187	pseudouridine synthase activity
CY657_RS18415	COG1061	Type III restriction enzyme res subunit
CY657_RS18435	COG0494	nUDIX hydrolase
CY657_RS18440	COG1349	DNA-binding transcription factor activity
CY657_RS18465	COG0628	permease
CY657_RS18480	COG0659	secondary active sulfate transmembrane transporter activity
CY657_RS18485	COG2239	Acts as a magnesium transporter
CY657_RS18490	COG4615	Cyclic peptide transporter
CY657_RS18495	COG3145	DNA-N1-methyladenine dioxygenase activity
CY657_RS18500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CY657_RS18500	COG2169	Transcriptional regulator
CY657_RS18515	COG2198	Histidine kinase
CY657_RS18515	COG0642	Histidine kinase
CY657_RS18525	COG0784	Response regulator, receiver
CY657_RS18525	COG2205	protein histidine kinase activity
CY657_RS18550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS18555	COG0584	glycerophosphoryl diester phosphodiesterase
CY657_RS18560	COG2271	Major facilitator Superfamily
CY657_RS18565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CY657_RS18575	COG0247	lactate metabolic process
CY657_RS18585	COG2271	Major facilitator Superfamily
CY657_RS18595	COG1414	Transcriptional regulator
CY657_RS18610	COG5464	transposase or invertase
CY657_RS18620	COG0318	PFAM AMP-dependent synthetase and ligase
CY657_RS18645	COG1169	isochorismate synthase
CY657_RS18650	COG2153	protein acetylation
CY657_RS18665	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY657_RS18670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CY657_RS18680	COG0839	Belongs to the complex I subunit 6 family
CY657_RS18730	COG0583	DNA-binding transcription factor activity
CY657_RS18735	COG0436	Aminotransferase
CY657_RS18745	COG0490	domain, Protein
CY657_RS18745	COG0471	metal ion transport
CY657_RS18750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS18770	COG0280	phosphate acetyltransferase
CY657_RS18770	COG0857	belongs to the CobB CobQ family
CY657_RS18775	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CY657_RS18780	COG0622	Phosphoesterase
CY657_RS18785	COG0625	glutathione transferase activity
CY657_RS18790	COG0625	glutathione transferase activity
CY657_RS18795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CY657_RS18800	COG1090	epimerase
CY657_RS18810	COG4598	ABC transporter
CY657_RS18815	COG4160	amino acid transport
CY657_RS18835	COG0163	prenyltransferase activity
CY657_RS18840	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CY657_RS18845	COG1286	toxin biosynthetic process
CY657_RS18850	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CY657_RS18855	COG0285	dihydrofolate synthase activity
CY657_RS18865	COG0586	Pfam SNARE associated Golgi protein
CY657_RS18875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CY657_RS18895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CY657_RS18910	COG3101	peptidyl-lysine hydroxylation
CY657_RS18915	COG0730	response to heat
CY657_RS18940	COG2062	phosphohistidine phosphatase, SixA
CY657_RS18955	COG3691	Protein conserved in bacteria
CY657_RS18965	COG2853	Lipoprotein
CY657_RS18970	COG2116	formate transmembrane transporter activity
CY657_RS18990	COG0583	DNA-binding transcription factor activity
CY657_RS18995	COG0590	tRNA wobble adenosine to inosine editing
CY657_RS19000	COG2807	transmembrane transport
CY657_RS19010	COG0436	Aminotransferase
CY657_RS19020	COG3275	phosphorelay sensor kinase activity
CY657_RS19025	COG3279	Response regulator of the LytR AlgR family
CY657_RS19040	COG3961	Belongs to the TPP enzyme family
CY657_RS19045	COG0667	Aldo Keto reductase
CY657_RS19060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY657_RS19065	COG2200	EAL domain
CY657_RS19065	COG2199	diguanylate cyclase activity
CY657_RS19080	COG3415	Transposase
CY657_RS19085	COG3415	Transposase
CY657_RS19120	COG0583	DNA-binding transcription factor activity
CY657_RS19125	COG0385	Bile acid
CY657_RS19130	COG3530	Putative quorum-sensing-regulated virulence factor
CY657_RS19150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CY657_RS19185	COG4319	ketosteroid isomerase
CY657_RS19195	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CY657_RS19200	COG4208	sulfate ABC transporter
CY657_RS19205	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CY657_RS19210	COG4150	thiosulfate binding
CY657_RS19220	COG2837	iron assimilation
CY657_RS19240	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY657_RS19330	COG4810	utilization protein
CY657_RS19340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CY657_RS19345	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CY657_RS19350	COG5342	invasion associated locus B
CY657_RS19360	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS19360	COG0493	'glutamate synthase
CY657_RS19370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS19380	COG1393	Belongs to the ArsC family
CY657_RS19395	COG0400	carboxylic ester hydrolase activity
CY657_RS19400	COG1444	tRNA N-acetyltransferase activity
CY657_RS19405	COG2321	neutral zinc metallopeptidase
CY657_RS19415	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CY657_RS19425	COG2716	regulation of RNA biosynthetic process
CY657_RS19430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CY657_RS19435	COG0628	permease
CY657_RS19440	COG4783	chaperone-mediated protein folding
CY657_RS19445	COG1393	Belongs to the ArsC family
CY657_RS19460	COG2233	PERMEase
CY657_RS19470	COG2723	6-phospho-beta-galactosidase activity
CY657_RS19485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CY657_RS19500	COG2200	EAL domain
CY657_RS19520	COG0641	radical SAM
CY657_RS19525	COG3119	arylsulfatase activity
CY657_RS19535	COG0516	GMP reductase activity
CY657_RS19535	COG0517	IMP dehydrogenase activity
CY657_RS19545	COG1645	bacterial-type flagellum-dependent swarming motility
CY657_RS19565	COG2976	Protein conserved in bacteria
CY657_RS19600	COG4953	penicillin-binding protein 1C
CY657_RS19605	COG2373	Large extracellular alpha-helical protein
CY657_RS19610	COG2897	thiosulfate sulfurtransferase activity
CY657_RS19630	COG2975	iron-sulfur cluster assembly
CY657_RS19635	COG0633	Ferredoxin
CY657_RS19655	COG0822	iron-sulfur transferase activity
CY657_RS19685	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CY657_RS19690	COG3683	transport system, periplasmic component
CY657_RS19695	COG3711	transcriptional antiterminator
CY657_RS19700	COG2814	Major facilitator Superfamily
CY657_RS19705	COG2017	converts alpha-aldose to the beta-anomer
CY657_RS19710	COG0477	Major facilitator Superfamily
CY657_RS19710	COG2814	Major facilitator Superfamily
CY657_RS19715	COG0457	Tetratricopeptide repeat
CY657_RS19720	COG1940	carbohydrate kinase activity
CY657_RS19725	COG2259	Doxx family
CY657_RS19735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CY657_RS19735	COG1017	nitric oxide dioxygenase activity
CY657_RS19740	COG0347	Belongs to the P(II) protein family
CY657_RS19745	COG2204	response regulator
CY657_RS19750	COG3170	Tfp pilus assembly protein FimV
CY657_RS19755	COG2205	protein histidine kinase activity
CY657_RS19765	COG0047	phosphoribosylformylglycinamidine synthase activity
CY657_RS19765	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CY657_RS19780	COG0560	Phosphoserine phosphatase
CY657_RS19785	COG1737	Transcriptional regulator
CY657_RS19790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS19800	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CY657_RS19820	COG0681	Belongs to the peptidase S26 family
CY657_RS19830	COG3086	response to oxidative stress
CY657_RS19835	COG3026	antisigma factor binding
CY657_RS19840	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CY657_RS19855	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CY657_RS19865	COG0513	Belongs to the DEAD box helicase family
CY657_RS19880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY657_RS19885	COG3118	belongs to the thioredoxin family
CY657_RS19890	COG3148	PFAM DTW domain containing protein
CY657_RS19900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY657_RS19905	COG5544	Lipoprotein
CY657_RS19910	COG0477	Major facilitator Superfamily
CY657_RS19940	COG0542	response to heat
CY657_RS19955	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CY657_RS19960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CY657_RS19970	COG1605	Chorismate mutase
CY657_RS19970	COG0077	Prephenate dehydratase
CY657_RS19980	COG0287	Prephenate dehydrogenase
CY657_RS19980	COG1605	Chorismate mutase
CY657_RS19985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CY657_RS19995	COG2199	diguanylate cyclase activity
CY657_RS20000	COG2885	chlorophyll binding
CY657_RS20035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CY657_RS20040	COG4137	Cytochrome C assembly protein
CY657_RS20045	COG4536	flavin adenine dinucleotide binding
CY657_RS20060	COG0497	DNA recombination
CY657_RS20075	COG2867	negative regulation of translational initiation
CY657_RS20090	COG0582	viral genome integration into host DNA
CY657_RS20170	COG2207	Transcriptional regulator
CY657_RS20170	COG3708	Transcriptional regulator
CY657_RS20175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS20210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS20220	COG0235	Class ii aldolase
CY657_RS20230	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS20245	COG2197	response regulator
CY657_RS20250	COG3539	Fimbrial protein
CY657_RS20260	COG3188	usher protein
CY657_RS20280	COG3121	Chaperone
CY657_RS20285	COG3539	Fimbrial protein
CY657_RS20295	COG3284	Transcriptional regulator
CY657_RS20300	COG0583	DNA-binding transcription factor activity
CY657_RS20310	COG0640	Transcriptional regulator
CY657_RS20315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CY657_RS20330	COG2916	Histone family protein nucleoid-structuring protein H-NS
CY657_RS20355	COG4575	ribosome binding
CY657_RS20360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY657_RS20365	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY657_RS20370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CY657_RS20380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CY657_RS20395	COG4176	ABC-type proline glycine betaine transport system permease component
CY657_RS20405	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CY657_RS20415	COG1846	Transcriptional regulator
CY657_RS20420	COG1566	PFAM secretion protein HlyD family protein
CY657_RS20425	COG2814	Major facilitator Superfamily
CY657_RS20430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CY657_RS20450	COG1238	metal cluster binding
CY657_RS20455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY657_RS20460	COG2823	Periplasmic or secreted lipoprotein
CY657_RS20490	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CY657_RS20515	COG1546	Belongs to the CinA family
CY657_RS20520	COG0803	Belongs to the bacterial solute-binding protein 9 family
CY657_RS20525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY657_RS20530	COG1121	(ABC) transporter
CY657_RS20540	COG2951	lytic endotransglycosylase activity
CY657_RS20545	COG3730	PTS system glucitol sorbitol-specific
CY657_RS20550	COG3732	PTS system glucitol sorbitol-specific
CY657_RS20560	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS20565	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS20570	COG1349	DNA-binding transcription factor activity
CY657_RS20600	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CY657_RS20605	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CY657_RS20610	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS20615	COG1609	Transcriptional regulator
CY657_RS20620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS20620	COG1263	PTS System
CY657_RS20625	COG2723	6-phospho-beta-galactosidase activity
CY657_RS20635	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CY657_RS20645	COG3260	NADH ubiquinone oxidoreductase 20
CY657_RS20650	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY657_RS20655	COG3261	NADH dehydrogenase
CY657_RS20655	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CY657_RS20660	COG0650	Formate hydrogenlyase subunit 4
CY657_RS20665	COG0651	ATP synthesis coupled electron transport
CY657_RS20670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS20690	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CY657_RS20695	COG0298	carbon dioxide binding
CY657_RS20700	COG0409	Hydrogenase expression formation protein
CY657_RS20705	COG0309	Hydrogenase expression formation protein (HypE)
CY657_RS20715	COG2723	6-phospho-beta-galactosidase activity
CY657_RS20725	COG4580	involved in the transport of maltose and maltodextrins
CY657_RS20735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS20740	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS20745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS20750	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS20755	COG1940	carbohydrate kinase activity
CY657_RS20760	COG1609	Transcriptional regulator
CY657_RS20770	COG1121	(ABC) transporter
CY657_RS20775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY657_RS20780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY657_RS20795	COG0679	Auxin Efflux Carrier
CY657_RS20815	COG3720	iron ion transport
CY657_RS20820	COG4558	Periplasmic binding protein
CY657_RS20825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY657_RS20870	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CY657_RS20875	COG0163	prenyltransferase activity
CY657_RS20905	COG1388	LysM domain
CY657_RS20905	COG4942	peptidase
CY657_RS20965	COG2234	aminopeptidase activity
CY657_RS20985	COG0720	synthase
CY657_RS20990	COG0602	queuosine metabolic process
CY657_RS21010	COG3956	TIGRFAM MazG family protein
CY657_RS21015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CY657_RS21025	COG3437	response regulator, receiver
CY657_RS21025	COG3850	Histidine kinase
CY657_RS21025	COG4999	Histidine kinase
CY657_RS21025	COG2205	protein histidine kinase activity
CY657_RS21035	COG1929	Belongs to the glycerate kinase type-1 family
CY657_RS21040	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS21045	COG4948	Mandelate Racemase Muconate Lactonizing
CY657_RS21050	COG2271	Major facilitator Superfamily
CY657_RS21055	COG0716	FMN binding
CY657_RS21060	COG0564	pseudouridine synthase activity
CY657_RS21065	COG3098	single-species biofilm formation
CY657_RS21080	COG1611	Belongs to the LOG family
CY657_RS21085	COG0814	amino acid
CY657_RS21090	COG1760	l-serine dehydratase
CY657_RS21095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY657_RS21105	COG0477	Major facilitator Superfamily
CY657_RS21115	COG1464	Belongs to the NlpA lipoprotein family
CY657_RS21120	COG2011	ABC-type metal ion transport system permease component
CY657_RS21125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CY657_RS21140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS21155	COG1454	alcohol dehydrogenase
CY657_RS21160	COG0235	Class ii aldolase
CY657_RS21165	COG0738	Major facilitator superfamily
CY657_RS21185	COG1349	DNA-binding transcription factor activity
CY657_RS21195	COG2363	Small membrane protein
CY657_RS21200	COG0583	DNA-binding transcription factor activity
CY657_RS21210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CY657_RS21215	COG2166	iron-sulfur cluster assembly
CY657_RS21220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CY657_RS21225	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CY657_RS21390	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CY657_RS21420	COG1012	belongs to the aldehyde dehydrogenase family
CY657_RS21420	COG1454	alcohol dehydrogenase
CY657_RS21425	COG4656	Part of a membrane complex involved in electron transport
CY657_RS21455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CY657_RS21460	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY657_RS21465	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CY657_RS21465	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CY657_RS21475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CY657_RS21480	COG1074	ATP-dependent DNA helicase activity
CY657_RS21485	COG1025	Belongs to the peptidase M16 family
CY657_RS21490	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CY657_RS21495	COG4967	type IV pilus modification protein PilV
CY657_RS21505	COG4795	General secretion pathway protein
CY657_RS21510	COG2165	general secretion pathway protein
CY657_RS21545	COG0861	Integral membrane protein TerC family
CY657_RS21555	COG0667	Aldo Keto reductase
CY657_RS21570	COG1609	Transcriptional regulator
CY657_RS21580	COG2186	Transcriptional regulator
CY657_RS21585	COG2723	6-phospho-beta-galactosidase activity
CY657_RS21590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS21595	COG1609	Transcriptional regulator
CY657_RS21605	COG0583	DNA-binding transcription factor activity
CY657_RS21610	COG1794	racemase activity, acting on amino acids and derivatives
CY657_RS21615	COG1917	Cupin 2, conserved barrel domain protein
CY657_RS21620	COG1175	transmembrane transport
CY657_RS21625	COG0395	ABC-type sugar transport system, permease component
CY657_RS21630	COG3842	ATPase activity
CY657_RS21660	COG2814	Major facilitator Superfamily
CY657_RS21665	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS21670	COG0823	Involved in the tonB-independent uptake of proteins
CY657_RS21680	COG0183	Belongs to the thiolase family
CY657_RS21695	COG0814	amino acid
CY657_RS21700	COG0667	Aldo Keto reductase
CY657_RS21750	COG0697	spore germination
CY657_RS21755	COG1846	Transcriptional regulator
CY657_RS21760	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CY657_RS21770	COG0582	viral genome integration into host DNA
CY657_RS21775	COG4974	Belongs to the 'phage' integrase family
CY657_RS21785	COG3539	Fimbrial protein
CY657_RS21790	COG3121	Chaperone
CY657_RS21795	COG3188	usher protein
CY657_RS21800	COG3539	Fimbrial protein
CY657_RS21805	COG3539	Fimbrial protein
CY657_RS21810	COG3539	Fimbrial protein
CY657_RS21820	COG2388	GCN5-related N-acetyl-transferase
CY657_RS21825	COG3592	Divergent 4Fe-4S mono-cluster
CY657_RS21840	COG1289	transmembrane transporter activity
CY657_RS21845	COG1538	Outer membrane efflux protein
CY657_RS21860	COG1393	Belongs to the ArsC family
CY657_RS21865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CY657_RS21905	COG0667	Aldo Keto reductase
CY657_RS21920	COG2814	Major facilitator Superfamily
CY657_RS21940	COG3646	Phage regulatory protein
CY657_RS21950	COG4974	Belongs to the 'phage' integrase family
CY657_RS21960	COG4942	peptidase
CY657_RS21985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CY657_RS21995	COG4974	Belongs to the 'phage' integrase family
CY657_RS22000	COG0716	FMN binding
CY657_RS22010	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CY657_RS22020	COG1272	protein, Hemolysin III
CY657_RS22030	COG1737	Transcriptional regulator
CY657_RS22035	COG2723	6-phospho-beta-galactosidase activity
CY657_RS22055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CY657_RS22060	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS22080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CY657_RS22085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CY657_RS22090	COG0006	proline dipeptidase activity
CY657_RS22110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CY657_RS22115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY657_RS22130	COG2968	Membrane
CY657_RS22140	COG0668	transmembrane transport
CY657_RS22145	COG0191	fructose-bisphosphate aldolase activity
CY657_RS22160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CY657_RS22165	COG0501	Belongs to the peptidase M48B family
CY657_RS22200	COG2814	Major facilitator Superfamily
CY657_RS22210	COG2356	endonuclease I
CY657_RS22215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CY657_RS22220	COG0189	ligase activity
CY657_RS22240	COG2805	Type II/IV secretion system protein
CY657_RS22245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CY657_RS22250	COG0762	integral membrane protein
CY657_RS22265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CY657_RS22275	COG3171	Protein conserved in bacteria
CY657_RS22285	COG1194	a g-specific adenine glycosylase
CY657_RS22300	COG2211	Major facilitator Superfamily
CY657_RS22305	COG1982	Orn Lys Arg decarboxylase major
CY657_RS22315	COG1811	Na channel or pump
CY657_RS22330	COG0626	cystathionine gamma-synthase activity
CY657_RS22335	COG0583	DNA-binding transcription factor activity
CY657_RS22355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY657_RS22360	COG0754	glutathionylspermidine amidase activity
CY657_RS22370	COG0625	glutathione transferase activity
CY657_RS22395	COG2211	Major facilitator Superfamily
CY657_RS22400	COG0848	biopolymer transport protein
CY657_RS22410	COG0626	cystathionine gamma-synthase activity
CY657_RS22415	COG0586	Pfam SNARE associated Golgi protein
CY657_RS22420	COG2207	Transcriptional regulator
CY657_RS22425	COG1979	alcohol dehydrogenase
CY657_RS22430	COG0656	L-ascorbic acid biosynthetic process
CY657_RS22440	COG1032	radical SAM domain protein
CY657_RS22445	COG2132	Multicopper oxidase
CY657_RS22450	COG0204	Acyl-transferase
CY657_RS22455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CY657_RS22460	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CY657_RS22465	COG3111	PFAM Bacterial OB fold (BOF) protein
CY657_RS22475	COG0642	Histidine kinase
CY657_RS22480	COG2249	NAD(P)H dehydrogenase (quinone) activity
CY657_RS22485	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CY657_RS22495	COG3150	esterase
CY657_RS22500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CY657_RS22505	COG3151	Protein conserved in bacteria
CY657_RS22510	COG0494	nUDIX hydrolase
CY657_RS22525	COG0754	glutathionylspermidine amidase activity
CY657_RS22530	COG3384	dioxygenase
CY657_RS22545	COG2960	long-chain fatty acid transporting porin activity
CY657_RS22565	COG3025	triphosphatase activity
CY657_RS22570	COG4991	sh3 domain protein
CY657_RS22585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CY657_RS22645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CY657_RS22650	COG0358	DNA primase activity
CY657_RS22655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CY657_RS22820	COG4695	Portal protein
CY657_RS22890	COG0582	viral genome integration into host DNA
CY657_RS22910	COG2197	response regulator
CY657_RS22915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY657_RS22915	COG2205	protein histidine kinase activity
CY657_RS22915	COG0784	Response regulator, receiver
CY657_RS22915	COG2198	Histidine kinase
CY657_RS22925	COG3247	response to pH
CY657_RS22995	COG2376	Dihydroxyacetone kinase
CY657_RS23000	COG1461	Dihydroxyacetone kinase
CY657_RS23015	COG2375	cellular response to nickel ion
CY657_RS23020	COG1695	Transcriptional regulator
CY657_RS23070	COG0446	pyridine nucleotide-disulphide oxidoreductase
CY657_RS23070	COG1902	pentaerythritol trinitrate reductase activity
CY657_RS23090	COG1451	nucleotide metabolic process
CY657_RS23095	COG0673	inositol 2-dehydrogenase activity
CY657_RS23100	COG0861	Integral membrane protein TerC family
CY657_RS23115	COG2721	sulfolactate sulfo-lyase activity
CY657_RS23125	COG2271	Major facilitator Superfamily
CY657_RS23130	COG2186	Transcriptional regulator
CY657_RS23135	COG0586	Pfam SNARE associated Golgi protein
CY657_RS23145	COG1422	Protein of unknown function (DUF1090)
CY657_RS23150	COG4575	ribosome binding
CY657_RS23155	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CY657_RS23165	COG2259	Doxx family
CY657_RS23170	COG0435	Glutathione S-transferase
CY657_RS23175	COG3152	Membrane
CY657_RS23180	COG0583	DNA-binding transcription factor activity
CY657_RS23185	COG1741	Belongs to the pirin family
CY657_RS23210	COG1929	Belongs to the glycerate kinase type-1 family
CY657_RS23215	COG2084	Dehydrogenase
CY657_RS23225	COG2271	Major facilitator Superfamily
CY657_RS23235	COG2721	sulfolactate sulfo-lyase activity
CY657_RS23240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CY657_RS23260	COG2823	Periplasmic or secreted lipoprotein
CY657_RS23265	COG0701	Predicted permease
CY657_RS23270	COG0702	epimerase
CY657_RS23275	COG0693	protein deglycase activity
CY657_RS23290	COG3153	acetyltransferase
CY657_RS23295	COG3154	lipid carrier protein
CY657_RS23300	COG0826	peptidase U32
CY657_RS23305	COG0826	peptidase U32
CY657_RS23310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY657_RS23355	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CY657_RS23380	COG0814	amino acid
CY657_RS23425	COG0195	Participates in both transcription termination and antitermination
CY657_RS23465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CY657_RS23475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CY657_RS23480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CY657_RS23490	COG1534	Rna-binding protein
CY657_RS23500	COG2027	D-alanyl-D-alanine carboxypeptidase
CY657_RS23510	COG0697	spore germination
CY657_RS23525	COG0142	geranyltranstransferase activity
CY657_RS23530	COG3423	Transcriptional regulator
CY657_RS23540	COG5007	Belongs to the BolA IbaG family
CY657_RS23545	COG3113	response to antibiotic
CY657_RS23550	COG2854	intermembrane phospholipid transfer
CY657_RS23555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CY657_RS23560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CY657_RS23565	COG1127	ABC transporter
CY657_RS23575	COG0530	calcium, potassium:sodium antiporter activity
CY657_RS23585	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CY657_RS23590	COG3117	lipopolysaccharide transmembrane transporter activity
CY657_RS23595	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CY657_RS23600	COG1137	ATPase activity
CY657_RS23605	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CY657_RS23610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CY657_RS23615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS23625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY657_RS23630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY657_RS23635	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CY657_RS23640	COG2198	Histidine kinase
CY657_RS23640	COG0784	Response regulator, receiver
CY657_RS23640	COG5002	protein histidine kinase activity
CY657_RS23645	COG1312	Catalyzes the dehydration of D-mannonate
CY657_RS23650	COG1063	alcohol dehydrogenase
CY657_RS23655	COG2271	Major facilitator Superfamily
CY657_RS23660	COG1242	4 iron, 4 sulfur cluster binding
CY657_RS23665	COG0070	glutamate synthase
CY657_RS23665	COG0069	glutamate synthase activity
CY657_RS23665	COG0067	glutamate synthase
CY657_RS23670	COG0493	'glutamate synthase
CY657_RS23680	COG2969	positive regulation of protein catabolic process
CY657_RS23685	COG0625	glutathione transferase activity
CY657_RS23700	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CY657_RS23705	COG3105	Protein conserved in bacteria
CY657_RS23710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY657_RS23715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY657_RS23740	COG2732	(Barnase) inhibitor
CY657_RS23745	COG1289	transmembrane transporter activity
CY657_RS23760	COG0583	DNA-binding transcription factor activity
CY657_RS23765	COG0312	modulator of DNA gyrase
CY657_RS23770	COG3164	Protein of unknown function
CY657_RS23775	COG1530	ribonuclease E activity
CY657_RS23785	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CY657_RS23790	COG1792	Involved in formation and maintenance of cell shape
CY657_RS23795	COG1077	Cell shape determining protein MreB Mrl
CY657_RS23800	COG2199	diguanylate cyclase activity
CY657_RS23800	COG2200	EAL domain
CY657_RS23825	COG0511	ligase activity, forming carbon-carbon bonds
CY657_RS23830	COG0439	Biotin carboxylase
CY657_RS23835	COG3924	membrane
CY657_RS23840	COG4145	pantothenate transmembrane transporter activity
CY657_RS23865	COG1309	transcriptional regulator
CY657_RS23870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CY657_RS23875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS23910	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CY657_RS23930	COG0551	DNA topoisomerase type I activity
CY657_RS23940	COG0758	DNA mediated transformation
CY657_RS23970	COG3036	rescue of stalled ribosome
CY657_RS23975	COG0789	Transcriptional regulator
CY657_RS23990	COG0202	RNA polymerase activity
CY657_RS24015	COG0201	protein transport
CY657_RS24080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CY657_RS24095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CY657_RS24120	COG0051	transcription antitermination factor activity, RNA binding
CY657_RS24175	COG2964	Protein conserved in bacteria
CY657_RS24180	COG0545	Peptidyl-prolyl cis-trans isomerase
CY657_RS24190	COG1047	Peptidyl-prolyl cis-trans
CY657_RS24195	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CY657_RS24210	COG0488	(ABC) transporter
CY657_RS24220	COG0429	hydrolase of the alpha beta-hydrolase fold
CY657_RS24230	COG3954	Phosphoribulokinase
CY657_RS24235	COG1765	OsmC-like protein
CY657_RS24245	COG1289	transmembrane transporter activity
CY657_RS24250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CY657_RS24275	COG0738	Major facilitator superfamily
CY657_RS24280	COG0402	S-adenosylhomocysteine deaminase activity
CY657_RS24285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CY657_RS24310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CY657_RS24315	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CY657_RS24320	COG3266	domain, Protein
CY657_RS24335	COG4796	Type ii and iii secretion system protein
CY657_RS24360	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CY657_RS24365	COG0494	nUDIX hydrolase
CY657_RS24375	COG1011	Hydrolase
CY657_RS24380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CY657_RS24405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CY657_RS24410	COG2183	response to ionizing radiation
CY657_RS24415	COG1918	ferrous iron import across plasma membrane
CY657_RS24440	COG1040	competence protein
CY657_RS24450	COG2610	gluconate transmembrane transporter activity
CY657_RS24455	COG1640	4-alpha-glucanotransferase
CY657_RS24460	COG0058	SHG alpha-glucan phosphorylase activity
CY657_RS24470	COG1349	DNA-binding transcription factor activity
CY657_RS24485	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CY657_RS24500	COG0058	SHG alpha-glucan phosphorylase activity
CY657_RS24525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CY657_RS24535	COG2610	gluconate transmembrane transporter activity
CY657_RS24540	COG3265	gluconokinase activity
CY657_RS24545	COG1609	Transcriptional regulator
CY657_RS24550	COG1741	Belongs to the pirin family
CY657_RS24555	COG0673	inositol 2-dehydrogenase activity
CY657_RS24565	COG1247	-acetyltransferase
CY657_RS24570	COG0405	Gamma-glutamyltransferase
CY657_RS24580	COG0584	glycerophosphoryl diester phosphodiesterase
CY657_RS24630	COG0559	Belongs to the binding-protein-dependent transport system permease family
CY657_RS24635	COG0683	leucine binding
CY657_RS24650	COG0683	leucine binding
CY657_RS24660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CY657_RS24675	COG2177	Part of the ABC transporter FtsEX involved in
CY657_RS24680	COG2884	Cell division ATP-binding protein ftsE
CY657_RS24685	COG0552	protein localization to endoplasmic reticulum
CY657_RS24690	COG0742	ribosomal rna small subunit methyltransferase
CY657_RS24695	COG3776	membrane
CY657_RS24705	COG3714	YhhN family
CY657_RS24720	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CY657_RS24730	COG0477	Major facilitator Superfamily
CY657_RS24735	COG0628	permease
CY657_RS24775	COG3479	Phenolic acid decarboxylase
CY657_RS24785	COG0747	negative chemotaxis
CY657_RS24790	COG0601	transmembrane transport
CY657_RS24795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS24805	COG1124	(ABC) transporter
CY657_RS24815	COG2239	Acts as a magnesium transporter
CY657_RS24820	COG2081	HI0933 family
CY657_RS24825	COG0306	phosphate transporter
CY657_RS24835	COG0589	response to stress
CY657_RS24855	COG0671	phosphoesterase, PA-phosphatase related
CY657_RS24860	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CY657_RS24865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY657_RS24875	COG1454	alcohol dehydrogenase
CY657_RS24885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY657_RS24890	COG1028	Short-chain dehydrogenase reductase Sdr
CY657_RS24895	COG0583	DNA-binding transcription factor activity
CY657_RS24900	COG1295	ribonuclease BN
CY657_RS24905	COG0477	Major facilitator Superfamily
CY657_RS24910	COG2982	Protein involved in outer membrane biogenesis
CY657_RS24925	COG0612	Peptidase, M16
CY657_RS24935	COG2199	diguanylate cyclase activity
CY657_RS24935	COG2200	EAL domain
CY657_RS24940	COG0457	Tetratricopeptide repeat
CY657_RS24940	COG3118	belongs to the thioredoxin family
CY657_RS24945	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CY657_RS24950	COG1215	transferase activity, transferring glycosyl groups
CY657_RS24980	COG2194	sulfuric ester hydrolase activity
CY657_RS24995	COG0457	Tetratricopeptide repeat
CY657_RS25010	COG2894	cell division
CY657_RS25025	COG4608	Belongs to the ABC transporter superfamily
CY657_RS25030	COG0444	Belongs to the ABC transporter superfamily
CY657_RS25035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY657_RS25040	COG0601	transmembrane transport
CY657_RS25045	COG0747	negative chemotaxis
CY657_RS25080	COG2223	nitrite transmembrane transporter activity
CY657_RS25085	COG5571	outer membrane autotransporter
CY657_RS25090	COG2818	Glycosylase
CY657_RS25095	COG0456	acetyltransferase
CY657_RS25100	COG0243	molybdopterin cofactor binding
CY657_RS25105	COG2885	chlorophyll binding
CY657_RS25110	COG1609	Transcriptional regulator
CY657_RS25120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY657_RS25145	COG2814	Major facilitator Superfamily
CY657_RS25150	COG2944	sequence-specific DNA binding
CY657_RS25155	COG1278	Cold shock
CY657_RS25160	COG0488	(ABC) transporter
CY657_RS25185	COG3274	enterobacterial common antigen metabolic process
CY657_RS25190	COG4682	membrane
CY657_RS25195	COG4682	membrane
CY657_RS25210	COG4213	ABC transporter substrate-binding protein
CY657_RS25220	COG4214	carbohydrate transport
CY657_RS25225	COG2207	Transcriptional regulator
CY657_RS25225	COG1609	Transcriptional regulator
CY657_RS25230	COG2992	FlgJ-related protein
CY657_RS25235	COG0366	Alpha amylase catalytic
CY657_RS25240	COG3977	Valine--pyruvate aminotransferase
CY657_RS25245	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CY657_RS25250	COG1414	Transcriptional regulator
CY657_RS25255	COG3276	selenocysteine insertion sequence binding
CY657_RS25265	COG0625	glutathione transferase activity
CY657_RS25285	COG3722	fumarate hydratase activity
CY657_RS25305	COG2186	Transcriptional regulator
CY657_RS25315	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CY657_RS25335	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CY657_RS25340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CY657_RS25350	COG4942	peptidase
CY657_RS25355	COG2861	carbohydrate metabolic process
CY657_RS25360	COG0463	Glycosyl transferase, family 2
CY657_RS25370	COG0156	8-amino-7-oxononanoate synthase activity
CY657_RS25385	COG0859	PFAM glycosyl transferase family 9
CY657_RS25410	COG0859	PFAM glycosyl transferase family 9
CY657_RS25420	COG0438	transferase activity, transferring glycosyl groups
CY657_RS25425	COG1216	Glycosyl transferase, family 2
CY657_RS25430	COG1519	Transferase
CY657_RS25465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CY657_RS25495	COG0842	Transport permease protein
CY657_RS25500	COG1131	(ABC) transporter
CY657_RS25515	COG1561	YicC-like family, N-terminal region
CY657_RS25520	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CY657_RS25525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CY657_RS25525	COG2169	Transcriptional regulator
CY657_RS25535	COG2860	membrane
CY657_RS25555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CY657_RS25560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY657_RS25565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CY657_RS25570	COG1494	fructose-1,6-bisphosphatase
CY657_RS25580	COG3152	Membrane
CY657_RS25605	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CY657_RS25625	COG0786	glutamate:sodium symporter activity
CY657_RS25630	COG2233	PERMEase
CY657_RS25635	COG2982	Protein involved in outer membrane biogenesis
CY657_RS25640	COG1263	PTS System
CY657_RS25640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS25645	COG1486	melibiose metabolic process
CY657_RS25655	COG1501	Belongs to the glycosyl hydrolase 31 family
CY657_RS25660	COG2211	Major facilitator Superfamily
CY657_RS25695	COG1064	alcohol dehydrogenase
CY657_RS25705	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CY657_RS25720	COG1464	Belongs to the NlpA lipoprotein family
CY657_RS25745	COG0583	DNA-binding transcription factor activity
CY657_RS25780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY657_RS25790	COG2814	Major facilitator Superfamily
CY657_RS25800	COG1263	PTS System
CY657_RS25800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY657_RS25805	COG0697	spore germination
CY657_RS25820	COG2828	Protein conserved in bacteria
CY657_RS25825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CY657_RS25830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CY657_RS25835	COG0583	DNA-binding transcription factor activity
CY657_RS25840	COG3384	dioxygenase
CY657_RS25850	COG1609	Transcriptional regulator
CY657_RS25860	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS25860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY657_RS25865	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY657_RS25870	COG4580	involved in the transport of maltose and maltodextrins
CY657_RS25895	COG2188	Transcriptional regulator
CY657_RS25945	COG2271	Major facilitator Superfamily
CY657_RS25955	COG2197	response regulator
CY657_RS25960	COG0440	acetolactate synthase activity
CY657_RS25965	COG0028	Belongs to the TPP enzyme family
CY657_RS25990	COG2814	Major facilitator Superfamily
CY657_RS25995	COG0583	DNA-binding transcription factor activity
CY657_RS26000	COG2610	gluconate transmembrane transporter activity
CY657_RS26020	COG2149	membrane
CY657_RS26035	COG2188	Transcriptional regulator
CY657_RS26045	COG3645	SOS response
CY657_RS26060	COG5645	(Lipo)protein
CY657_RS26065	COG0823	Involved in the tonB-independent uptake of proteins
CY657_RS26070	COG2271	Major facilitator Superfamily
CY657_RS26080	COG0800	Aldolase
CY657_RS26085	COG3734	2-keto-3-deoxy-galactonokinase
CY657_RS26090	COG2186	Transcriptional regulator
CY657_RS26105	COG0561	phosphatase activity
CY657_RS26110	COG0187	DNA topoisomerase II activity