locus-tag	class	description
DBX64_RS00030	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
DBX64_RS00040	COG1739	Uncharacterized protein family UPF0029
DBX64_RS00080	COG0805	protein transport
DBX64_RS00100	COG3165	ubiquinone biosynthetic process from chorismate
DBX64_RS00130	COG0583	DNA-binding transcription factor activity
DBX64_RS00135	COG0697	spore germination
DBX64_RS00140	COG0561	phosphatase activity
DBX64_RS00145	COG2267	carboxylic ester hydrolase activity
DBX64_RS00150	COG1280	lysine exporter protein (LysE YggA)
DBX64_RS00160	COG1280	lysine exporter protein (LysE YggA)
DBX64_RS00190	COG0210	DNA helicase
DBX64_RS00195	COG1011	Hydrolase
DBX64_RS00225	COG3072	Adenylate cyclase
DBX64_RS00240	COG2959	enzyme of heme biosynthesis
DBX64_RS00245	COG3071	HemY protein
DBX64_RS00290	COG2244	polysaccharide biosynthetic process
DBX64_RS00295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DBX64_RS00300	COG0456	acetyltransferase
DBX64_RS00305	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DBX64_RS00310	COG1088	dTDP-glucose 4,6-dehydratase activity
DBX64_RS00315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DBX64_RS00320	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DBX64_RS00330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DBX64_RS00335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DBX64_RS00340	COG3118	belongs to the thioredoxin family
DBX64_RS00365	COG1811	Na channel or pump
DBX64_RS00375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBX64_RS00380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBX64_RS00390	COG0583	DNA-binding transcription factor activity
DBX64_RS00395	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DBX64_RS00410	COG3978	acetolactate synthase activity
DBX64_RS00430	COG3085	chromosome segregation
DBX64_RS00505	COG0583	DNA-binding transcription factor activity
DBX64_RS00520	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DBX64_RS00535	COG3443	Belongs to the bacterial solute-binding protein 9 family
DBX64_RS00540	COG2207	Transcriptional regulator
DBX64_RS00550	COG0371	Dehydrogenase
DBX64_RS00555	COG0697	spore germination
DBX64_RS00565	COG0583	DNA-binding transcription factor activity
DBX64_RS00575	COG0737	Belongs to the 5'-nucleotidase family
DBX64_RS00585	COG0460	homoserine dehydrogenase
DBX64_RS00585	COG0527	aspartate kinase activity
DBX64_RS00590	COG0626	cystathionine gamma-synthase activity
DBX64_RS00605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DBX64_RS00610	COG1609	Transcriptional regulator
DBX64_RS00615	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DBX64_RS00630	COG1575	Belongs to the MenA family. Type 1 subfamily
DBX64_RS00650	COG3678	ATP-independent chaperone mediated protein folding
DBX64_RS00655	COG0745	RESPONSE REGULATOR receiver
DBX64_RS00660	COG2205	protein histidine kinase activity
DBX64_RS00665	COG2258	MOSC domain
DBX64_RS00670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DBX64_RS00710	COG1129	ABC transporter
DBX64_RS00715	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS00720	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS00725	COG1454	alcohol dehydrogenase
DBX64_RS00735	COG2211	Major facilitator Superfamily
DBX64_RS00795	COG0205	6-phosphofructokinase activity
DBX64_RS00815	COG0437	4 iron, 4 sulfur cluster binding
DBX64_RS00820	COG2864	formate dehydrogenase
DBX64_RS00835	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DBX64_RS00845	COG0456	acetyltransferase
DBX64_RS00860	COG1011	Hydrolase
DBX64_RS00875	COG3852	Histidine kinase
DBX64_RS00890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DBX64_RS00910	COG0204	Acyl-transferase
DBX64_RS00920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DBX64_RS00925	COG3084	Protein conserved in bacteria
DBX64_RS00935	COG1763	Mo-molybdopterin cofactor biosynthetic process
DBX64_RS00960	COG2186	Transcriptional regulator
DBX64_RS00965	COG0477	Major facilitator Superfamily
DBX64_RS00970	COG1609	Transcriptional regulator
DBX64_RS00975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX64_RS00985	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS00990	COG1129	ABC transporter
DBX64_RS01020	COG1522	sequence-specific DNA binding
DBX64_RS01025	COG0716	FMN binding
DBX64_RS01040	COG3312	ion transport
DBX64_RS01095	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DBX64_RS01100	COG0573	inorganic phosphate transmembrane transporter activity
DBX64_RS01105	COG0581	inorganic phosphate transmembrane transporter activity
DBX64_RS01110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DBX64_RS01115	COG0704	Plays a role in the regulation of phosphate uptake
DBX64_RS01125	COG2382	esterase
DBX64_RS01130	COG0363	glucosamine-6-phosphate deaminase activity
DBX64_RS01135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DBX64_RS01140	COG2252	PERMEase
DBX64_RS01145	COG0431	NADPH-dependent FMN reductase
DBX64_RS01150	COG2091	lysine biosynthetic process via aminoadipic acid
DBX64_RS01180	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DBX64_RS01210	COG0187	DNA topoisomerase II activity
DBX64_RS01215	COG0561	phosphatase activity
DBX64_RS01230	COG2186	Transcriptional regulator
DBX64_RS01235	COG3734	2-keto-3-deoxy-galactonokinase
DBX64_RS01240	COG0800	Aldolase
DBX64_RS01250	COG2271	Major facilitator Superfamily
DBX64_RS01255	COG0823	Involved in the tonB-independent uptake of proteins
DBX64_RS01260	COG5645	(Lipo)protein
DBX64_RS01275	COG3645	SOS response
DBX64_RS01285	COG2188	Transcriptional regulator
DBX64_RS01300	COG2149	membrane
DBX64_RS01320	COG2610	gluconate transmembrane transporter activity
DBX64_RS01330	COG0583	DNA-binding transcription factor activity
DBX64_RS01335	COG2814	Major facilitator Superfamily
DBX64_RS01365	COG0028	Belongs to the TPP enzyme family
DBX64_RS01370	COG0440	acetolactate synthase activity
DBX64_RS01375	COG2197	response regulator
DBX64_RS01385	COG2271	Major facilitator Superfamily
DBX64_RS01425	COG2188	Transcriptional regulator
DBX64_RS01455	COG4580	involved in the transport of maltose and maltodextrins
DBX64_RS01460	COG1447	Phosphotransferase system cellobiose-specific component IIA
DBX64_RS01465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBX64_RS01465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBX64_RS01475	COG1609	Transcriptional regulator
DBX64_RS01485	COG3384	dioxygenase
DBX64_RS01490	COG0583	DNA-binding transcription factor activity
DBX64_RS01495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DBX64_RS01500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DBX64_RS01505	COG2828	Protein conserved in bacteria
DBX64_RS01520	COG0697	spore germination
DBX64_RS01525	COG1263	PTS System
DBX64_RS01525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX64_RS01535	COG2814	Major facilitator Superfamily
DBX64_RS01545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DBX64_RS01580	COG0583	DNA-binding transcription factor activity
DBX64_RS01605	COG1464	Belongs to the NlpA lipoprotein family
DBX64_RS01620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DBX64_RS01630	COG1064	alcohol dehydrogenase
DBX64_RS01665	COG0582	viral genome integration into host DNA
DBX64_RS01675	COG2211	Major facilitator Superfamily
DBX64_RS01680	COG1501	Belongs to the glycosyl hydrolase 31 family
DBX64_RS01690	COG1486	melibiose metabolic process
DBX64_RS01695	COG1263	PTS System
DBX64_RS01695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX64_RS01700	COG2982	Protein involved in outer membrane biogenesis
DBX64_RS01705	COG2233	PERMEase
DBX64_RS01710	COG0786	glutamate:sodium symporter activity
DBX64_RS01730	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DBX64_RS01755	COG3152	Membrane
DBX64_RS01765	COG1494	fructose-1,6-bisphosphatase
DBX64_RS01770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DBX64_RS01775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBX64_RS01780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DBX64_RS01800	COG2860	membrane
DBX64_RS01810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DBX64_RS01810	COG2169	Transcriptional regulator
DBX64_RS01815	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DBX64_RS01820	COG1561	YicC-like family, N-terminal region
DBX64_RS01840	COG1131	(ABC) transporter
DBX64_RS01845	COG0842	Transport permease protein
DBX64_RS01875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DBX64_RS01910	COG1519	Transferase
DBX64_RS01915	COG1216	Glycosyl transferase, family 2
DBX64_RS01920	COG0438	transferase activity, transferring glycosyl groups
DBX64_RS01930	COG0859	PFAM glycosyl transferase family 9
DBX64_RS01955	COG0859	PFAM glycosyl transferase family 9
DBX64_RS01970	COG0156	8-amino-7-oxononanoate synthase activity
DBX64_RS01980	COG0463	Glycosyl transferase, family 2
DBX64_RS01985	COG2861	carbohydrate metabolic process
DBX64_RS01990	COG4942	peptidase
DBX64_RS02000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DBX64_RS02005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DBX64_RS02025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DBX64_RS02035	COG2186	Transcriptional regulator
DBX64_RS02055	COG3722	fumarate hydratase activity
DBX64_RS02075	COG0625	glutathione transferase activity
DBX64_RS02085	COG3276	selenocysteine insertion sequence binding
DBX64_RS02090	COG1414	Transcriptional regulator
DBX64_RS02095	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DBX64_RS02100	COG3977	Valine--pyruvate aminotransferase
DBX64_RS02105	COG0366	Alpha amylase catalytic
DBX64_RS02110	COG2992	FlgJ-related protein
DBX64_RS02115	COG1609	Transcriptional regulator
DBX64_RS02115	COG2207	Transcriptional regulator
DBX64_RS02120	COG4214	carbohydrate transport
DBX64_RS02130	COG4213	ABC transporter substrate-binding protein
DBX64_RS02145	COG4682	membrane
DBX64_RS02150	COG4682	membrane
DBX64_RS02185	COG1278	Cold shock
DBX64_RS02190	COG2944	sequence-specific DNA binding
DBX64_RS02195	COG2814	Major facilitator Superfamily
DBX64_RS02215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX64_RS02225	COG1609	Transcriptional regulator
DBX64_RS02230	COG2885	chlorophyll binding
DBX64_RS02235	COG0243	molybdopterin cofactor binding
DBX64_RS02240	COG0456	acetyltransferase
DBX64_RS02245	COG2818	Glycosylase
DBX64_RS02250	COG5571	outer membrane autotransporter
DBX64_RS02255	COG2223	nitrite transmembrane transporter activity
DBX64_RS02280	COG0747	negative chemotaxis
DBX64_RS02285	COG0601	transmembrane transport
DBX64_RS02290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX64_RS02295	COG0444	Belongs to the ABC transporter superfamily
DBX64_RS02300	COG4608	Belongs to the ABC transporter superfamily
DBX64_RS02315	COG2894	cell division
DBX64_RS02325	COG1215	transferase activity, transferring glycosyl groups
DBX64_RS02345	COG2194	sulfuric ester hydrolase activity
DBX64_RS02375	COG1215	transferase activity, transferring glycosyl groups
DBX64_RS02380	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DBX64_RS02385	COG3118	belongs to the thioredoxin family
DBX64_RS02385	COG0457	Tetratricopeptide repeat
DBX64_RS02390	COG2200	EAL domain
DBX64_RS02390	COG2199	diguanylate cyclase activity
DBX64_RS02400	COG0612	Peptidase, M16
DBX64_RS02410	COG2982	Protein involved in outer membrane biogenesis
DBX64_RS02415	COG0477	Major facilitator Superfamily
DBX64_RS02420	COG1295	ribonuclease BN
DBX64_RS02425	COG0583	DNA-binding transcription factor activity
DBX64_RS02430	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS02435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBX64_RS02445	COG1454	alcohol dehydrogenase
DBX64_RS02455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBX64_RS02460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DBX64_RS02465	COG0671	phosphoesterase, PA-phosphatase related
DBX64_RS02485	COG0589	response to stress
DBX64_RS02495	COG0306	phosphate transporter
DBX64_RS02500	COG2081	HI0933 family
DBX64_RS02505	COG2239	Acts as a magnesium transporter
DBX64_RS02520	COG1124	(ABC) transporter
DBX64_RS02530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX64_RS02535	COG0601	transmembrane transport
DBX64_RS02540	COG0747	negative chemotaxis
DBX64_RS02550	COG3479	Phenolic acid decarboxylase
DBX64_RS02590	COG0628	permease
DBX64_RS02595	COG0477	Major facilitator Superfamily
DBX64_RS02605	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DBX64_RS02620	COG3714	YhhN family
DBX64_RS02630	COG3776	membrane
DBX64_RS02635	COG0742	ribosomal rna small subunit methyltransferase
DBX64_RS02640	COG0552	protein localization to endoplasmic reticulum
DBX64_RS02645	COG2884	Cell division ATP-binding protein ftsE
DBX64_RS02650	COG2177	Part of the ABC transporter FtsEX involved in
DBX64_RS02665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DBX64_RS02675	COG0683	leucine binding
DBX64_RS02685	COG0683	leucine binding
DBX64_RS02690	COG0559	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS02740	COG0584	glycerophosphoryl diester phosphodiesterase
DBX64_RS02750	COG0405	Gamma-glutamyltransferase
DBX64_RS02755	COG1247	-acetyltransferase
DBX64_RS02765	COG0673	inositol 2-dehydrogenase activity
DBX64_RS02770	COG1741	Belongs to the pirin family
DBX64_RS02775	COG1609	Transcriptional regulator
DBX64_RS02780	COG3265	gluconokinase activity
DBX64_RS02785	COG2610	gluconate transmembrane transporter activity
DBX64_RS02795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DBX64_RS02820	COG0058	SHG alpha-glucan phosphorylase activity
DBX64_RS02825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DBX64_RS02840	COG1349	DNA-binding transcription factor activity
DBX64_RS02850	COG0058	SHG alpha-glucan phosphorylase activity
DBX64_RS02855	COG1640	4-alpha-glucanotransferase
DBX64_RS02860	COG2610	gluconate transmembrane transporter activity
DBX64_RS02870	COG1040	competence protein
DBX64_RS02895	COG1918	ferrous iron import across plasma membrane
DBX64_RS02900	COG2183	response to ionizing radiation
DBX64_RS02905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DBX64_RS02930	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DBX64_RS02935	COG1011	Hydrolase
DBX64_RS02945	COG0494	nUDIX hydrolase
DBX64_RS02950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DBX64_RS02975	COG4796	Type ii and iii secretion system protein
DBX64_RS02990	COG3266	domain, Protein
DBX64_RS02995	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DBX64_RS03000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DBX64_RS03025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DBX64_RS03030	COG0402	S-adenosylhomocysteine deaminase activity
DBX64_RS03035	COG0738	Major facilitator superfamily
DBX64_RS03060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DBX64_RS03065	COG1289	transmembrane transporter activity
DBX64_RS03075	COG1765	OsmC-like protein
DBX64_RS03080	COG3954	Phosphoribulokinase
DBX64_RS03090	COG0429	hydrolase of the alpha beta-hydrolase fold
DBX64_RS03095	COG0488	(ABC) transporter
DBX64_RS03110	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DBX64_RS03115	COG1047	Peptidyl-prolyl cis-trans
DBX64_RS03125	COG0545	Peptidyl-prolyl cis-trans isomerase
DBX64_RS03130	COG2964	Protein conserved in bacteria
DBX64_RS03185	COG0051	transcription antitermination factor activity, RNA binding
DBX64_RS03210	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DBX64_RS03225	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DBX64_RS03290	COG0201	protein transport
DBX64_RS03315	COG0202	RNA polymerase activity
DBX64_RS03330	COG0789	Transcriptional regulator
DBX64_RS03335	COG3036	rescue of stalled ribosome
DBX64_RS03365	COG0758	DNA mediated transformation
DBX64_RS03375	COG0551	DNA topoisomerase type I activity
DBX64_RS03395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DBX64_RS03430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DBX64_RS03435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX64_RS03440	COG1309	transcriptional regulator
DBX64_RS03460	COG4145	pantothenate transmembrane transporter activity
DBX64_RS03465	COG3924	membrane
DBX64_RS03470	COG0439	Biotin carboxylase
DBX64_RS03475	COG0511	ligase activity, forming carbon-carbon bonds
DBX64_RS03500	COG2200	EAL domain
DBX64_RS03500	COG2199	diguanylate cyclase activity
DBX64_RS03505	COG1077	Cell shape determining protein MreB Mrl
DBX64_RS03510	COG1792	Involved in formation and maintenance of cell shape
DBX64_RS03515	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DBX64_RS03525	COG1530	ribonuclease E activity
DBX64_RS03530	COG3164	Protein of unknown function
DBX64_RS03535	COG0312	modulator of DNA gyrase
DBX64_RS03540	COG0583	DNA-binding transcription factor activity
DBX64_RS03555	COG1289	transmembrane transporter activity
DBX64_RS03560	COG2732	(Barnase) inhibitor
DBX64_RS03595	COG0471	metal ion transport
DBX64_RS03600	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DBX64_RS03605	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DBX64_RS03630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DBX64_RS03635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DBX64_RS03640	COG3105	Protein conserved in bacteria
DBX64_RS03645	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DBX64_RS03665	COG0625	glutathione transferase activity
DBX64_RS03670	COG2969	positive regulation of protein catabolic process
DBX64_RS03680	COG0493	'glutamate synthase
DBX64_RS03685	COG0070	glutamate synthase
DBX64_RS03685	COG0069	glutamate synthase activity
DBX64_RS03685	COG0067	glutamate synthase
DBX64_RS03690	COG1242	4 iron, 4 sulfur cluster binding
DBX64_RS03695	COG2271	Major facilitator Superfamily
DBX64_RS03700	COG1063	alcohol dehydrogenase
DBX64_RS03705	COG1312	Catalyzes the dehydration of D-mannonate
DBX64_RS03710	COG0784	Response regulator, receiver
DBX64_RS03710	COG2198	Histidine kinase
DBX64_RS03710	COG5002	protein histidine kinase activity
DBX64_RS03715	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DBX64_RS03720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DBX64_RS03725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS03735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS03740	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DBX64_RS03745	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DBX64_RS03750	COG1137	ATPase activity
DBX64_RS03755	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DBX64_RS03760	COG3117	lipopolysaccharide transmembrane transporter activity
DBX64_RS03765	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DBX64_RS03775	COG0530	calcium, potassium:sodium antiporter activity
DBX64_RS03780	COG1127	ABC transporter
DBX64_RS03785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DBX64_RS03790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DBX64_RS03795	COG2854	intermembrane phospholipid transfer
DBX64_RS03800	COG3113	response to antibiotic
DBX64_RS03805	COG5007	Belongs to the BolA IbaG family
DBX64_RS03815	COG3423	Transcriptional regulator
DBX64_RS03820	COG0142	geranyltranstransferase activity
DBX64_RS03835	COG0697	spore germination
DBX64_RS03845	COG2027	D-alanyl-D-alanine carboxypeptidase
DBX64_RS03855	COG1534	Rna-binding protein
DBX64_RS03865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DBX64_RS03870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DBX64_RS03880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DBX64_RS03920	COG0195	Participates in both transcription termination and antitermination
DBX64_RS03965	COG0814	amino acid
DBX64_RS03970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBX64_RS03975	COG0826	peptidase U32
DBX64_RS03980	COG0826	peptidase U32
DBX64_RS03985	COG3154	lipid carrier protein
DBX64_RS03990	COG3153	acetyltransferase
DBX64_RS04005	COG0693	protein deglycase activity
DBX64_RS04010	COG0702	epimerase
DBX64_RS04015	COG0701	Predicted permease
DBX64_RS04020	COG2823	Periplasmic or secreted lipoprotein
DBX64_RS04040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DBX64_RS04055	COG1063	alcohol dehydrogenase
DBX64_RS04060	COG3775	system Galactitol-specific IIC component
DBX64_RS04065	COG3414	Phosphotransferase system galactitol-specific IIB component
DBX64_RS04070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS04080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS04080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS04085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBX64_RS04085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBX64_RS04085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS04090	COG1105	Belongs to the carbohydrate kinase PfkB family
DBX64_RS04100	COG1349	DNA-binding transcription factor activity
DBX64_RS04105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX64_RS04110	COG2721	sulfolactate sulfo-lyase activity
DBX64_RS04115	COG2271	Major facilitator Superfamily
DBX64_RS04125	COG2084	Dehydrogenase
DBX64_RS04130	COG1929	Belongs to the glycerate kinase type-1 family
DBX64_RS04155	COG1741	Belongs to the pirin family
DBX64_RS04160	COG0583	DNA-binding transcription factor activity
DBX64_RS04165	COG3152	Membrane
DBX64_RS04170	COG0435	Glutathione S-transferase
DBX64_RS04175	COG2259	Doxx family
DBX64_RS04185	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
DBX64_RS04190	COG4575	ribosome binding
DBX64_RS04195	COG1422	Protein of unknown function (DUF1090)
DBX64_RS04205	COG0586	Pfam SNARE associated Golgi protein
DBX64_RS04210	COG2186	Transcriptional regulator
DBX64_RS04215	COG2271	Major facilitator Superfamily
DBX64_RS04225	COG2721	sulfolactate sulfo-lyase activity
DBX64_RS04240	COG0861	Integral membrane protein TerC family
DBX64_RS04245	COG0673	inositol 2-dehydrogenase activity
DBX64_RS04250	COG1451	nucleotide metabolic process
DBX64_RS04270	COG0446	pyridine nucleotide-disulphide oxidoreductase
DBX64_RS04270	COG1902	pentaerythritol trinitrate reductase activity
DBX64_RS04320	COG1695	Transcriptional regulator
DBX64_RS04325	COG2375	cellular response to nickel ion
DBX64_RS04340	COG1461	Dihydroxyacetone kinase
DBX64_RS04345	COG2376	Dihydroxyacetone kinase
DBX64_RS04415	COG3247	response to pH
DBX64_RS04425	COG2205	protein histidine kinase activity
DBX64_RS04425	COG2198	Histidine kinase
DBX64_RS04425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX64_RS04425	COG0784	Response regulator, receiver
DBX64_RS04430	COG2197	response regulator
DBX64_RS04455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DBX64_RS04460	COG0358	DNA primase activity
DBX64_RS04465	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DBX64_RS04530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DBX64_RS04545	COG4991	sh3 domain protein
DBX64_RS04550	COG3025	triphosphatase activity
DBX64_RS04575	COG2960	long-chain fatty acid transporting porin activity
DBX64_RS04590	COG3384	dioxygenase
DBX64_RS04595	COG0754	glutathionylspermidine amidase activity
DBX64_RS04610	COG0494	nUDIX hydrolase
DBX64_RS04615	COG3151	Protein conserved in bacteria
DBX64_RS04620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DBX64_RS04625	COG3150	esterase
DBX64_RS04635	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DBX64_RS04645	COG0642	Histidine kinase
DBX64_RS04655	COG3111	PFAM Bacterial OB fold (BOF) protein
DBX64_RS04660	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DBX64_RS04665	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DBX64_RS04670	COG0204	Acyl-transferase
DBX64_RS04675	COG2132	Multicopper oxidase
DBX64_RS04680	COG1032	radical SAM domain protein
DBX64_RS04690	COG0656	L-ascorbic acid biosynthetic process
DBX64_RS04695	COG1979	alcohol dehydrogenase
DBX64_RS04700	COG2207	Transcriptional regulator
DBX64_RS04705	COG0586	Pfam SNARE associated Golgi protein
DBX64_RS04710	COG0626	cystathionine gamma-synthase activity
DBX64_RS04720	COG0848	biopolymer transport protein
DBX64_RS04725	COG2211	Major facilitator Superfamily
DBX64_RS04750	COG0625	glutathione transferase activity
DBX64_RS04765	COG0754	glutathionylspermidine amidase activity
DBX64_RS04770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBX64_RS04795	COG0626	cystathionine gamma-synthase activity
DBX64_RS04830	COG1811	Na channel or pump
DBX64_RS04835	COG1982	Orn Lys Arg decarboxylase major
DBX64_RS04840	COG2211	Major facilitator Superfamily
DBX64_RS04855	COG1194	a g-specific adenine glycosylase
DBX64_RS04865	COG3171	Protein conserved in bacteria
DBX64_RS04875	COG4214	carbohydrate transport
DBX64_RS04890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DBX64_RS04905	COG0762	integral membrane protein
DBX64_RS04910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DBX64_RS04915	COG2805	Type II/IV secretion system protein
DBX64_RS04935	COG0189	ligase activity
DBX64_RS04940	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DBX64_RS04945	COG2356	endonuclease I
DBX64_RS04955	COG2814	Major facilitator Superfamily
DBX64_RS04990	COG0501	Belongs to the peptidase M48B family
DBX64_RS04995	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DBX64_RS05010	COG0191	fructose-bisphosphate aldolase activity
DBX64_RS05015	COG0668	transmembrane transport
DBX64_RS05025	COG2968	Membrane
DBX64_RS05040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBX64_RS05045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DBX64_RS05065	COG0006	proline dipeptidase activity
DBX64_RS05070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DBX64_RS05075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DBX64_RS05095	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS05100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBX64_RS05120	COG2723	6-phospho-beta-galactosidase activity
DBX64_RS05125	COG1737	Transcriptional regulator
DBX64_RS05135	COG1272	protein, Hemolysin III
DBX64_RS05145	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DBX64_RS05155	COG0716	FMN binding
DBX64_RS05160	COG4974	Belongs to the 'phage' integrase family
DBX64_RS05170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DBX64_RS05190	COG4942	peptidase
DBX64_RS05200	COG2814	Major facilitator Superfamily
DBX64_RS05215	COG0667	Aldo Keto reductase
DBX64_RS05255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DBX64_RS05260	COG1393	Belongs to the ArsC family
DBX64_RS05275	COG1538	Outer membrane efflux protein
DBX64_RS05280	COG1289	transmembrane transporter activity
DBX64_RS05295	COG3592	Divergent 4Fe-4S mono-cluster
DBX64_RS05300	COG2388	GCN5-related N-acetyl-transferase
DBX64_RS05310	COG3539	Fimbrial protein
DBX64_RS05315	COG3539	Fimbrial protein
DBX64_RS05320	COG3539	Fimbrial protein
DBX64_RS05325	COG3188	usher protein
DBX64_RS05330	COG3121	Chaperone
DBX64_RS05335	COG3539	Fimbrial protein
DBX64_RS05345	COG4974	Belongs to the 'phage' integrase family
DBX64_RS05350	COG0582	viral genome integration into host DNA
DBX64_RS05360	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
DBX64_RS05365	COG1846	Transcriptional regulator
DBX64_RS05370	COG0697	spore germination
DBX64_RS05420	COG0667	Aldo Keto reductase
DBX64_RS05425	COG0814	amino acid
DBX64_RS05440	COG0183	Belongs to the thiolase family
DBX64_RS05450	COG0823	Involved in the tonB-independent uptake of proteins
DBX64_RS05455	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS05460	COG2814	Major facilitator Superfamily
DBX64_RS05495	COG3842	ATPase activity
DBX64_RS05500	COG0395	ABC-type sugar transport system, permease component
DBX64_RS05505	COG1175	transmembrane transport
DBX64_RS05510	COG1917	Cupin 2, conserved barrel domain protein
DBX64_RS05515	COG1794	racemase activity, acting on amino acids and derivatives
DBX64_RS05520	COG0583	DNA-binding transcription factor activity
DBX64_RS05530	COG1609	Transcriptional regulator
DBX64_RS05535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBX64_RS05540	COG2723	6-phospho-beta-galactosidase activity
DBX64_RS05545	COG2186	Transcriptional regulator
DBX64_RS05555	COG1609	Transcriptional regulator
DBX64_RS05575	COG0667	Aldo Keto reductase
DBX64_RS05585	COG0861	Integral membrane protein TerC family
DBX64_RS05620	COG2165	general secretion pathway protein
DBX64_RS05625	COG4795	General secretion pathway protein
DBX64_RS05635	COG4967	type IV pilus modification protein PilV
DBX64_RS05640	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DBX64_RS05645	COG1025	Belongs to the peptidase M16 family
DBX64_RS05650	COG1074	ATP-dependent DNA helicase activity
DBX64_RS05655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DBX64_RS05665	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DBX64_RS05665	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DBX64_RS05670	COG0860	N-Acetylmuramoyl-L-alanine amidase
DBX64_RS05675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DBX64_RS05705	COG4656	Part of a membrane complex involved in electron transport
DBX64_RS05710	COG1454	alcohol dehydrogenase
DBX64_RS05710	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS05740	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
DBX64_RS05910	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DBX64_RS05915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DBX64_RS05920	COG2166	iron-sulfur cluster assembly
DBX64_RS05925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DBX64_RS05935	COG0583	DNA-binding transcription factor activity
DBX64_RS05940	COG2363	Small membrane protein
DBX64_RS05950	COG1349	DNA-binding transcription factor activity
DBX64_RS05970	COG0738	Major facilitator superfamily
DBX64_RS05975	COG0235	Class ii aldolase
DBX64_RS05980	COG1454	alcohol dehydrogenase
DBX64_RS06000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBX64_RS06015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DBX64_RS06020	COG2011	ABC-type metal ion transport system permease component
DBX64_RS06025	COG1464	Belongs to the NlpA lipoprotein family
DBX64_RS06030	COG0477	Major facilitator Superfamily
DBX64_RS06040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DBX64_RS06045	COG1760	l-serine dehydratase
DBX64_RS06050	COG0814	amino acid
DBX64_RS06055	COG1611	Belongs to the LOG family
DBX64_RS06070	COG3098	single-species biofilm formation
DBX64_RS06075	COG0564	pseudouridine synthase activity
DBX64_RS06080	COG0716	FMN binding
DBX64_RS06085	COG2271	Major facilitator Superfamily
DBX64_RS06090	COG4948	Mandelate Racemase Muconate Lactonizing
DBX64_RS06095	COG4948	Mandelate Racemase Muconate Lactonizing
DBX64_RS06100	COG1929	Belongs to the glycerate kinase type-1 family
DBX64_RS06105	COG3437	response regulator, receiver
DBX64_RS06105	COG3850	Histidine kinase
DBX64_RS06105	COG2205	protein histidine kinase activity
DBX64_RS06105	COG4999	Histidine kinase
DBX64_RS06115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DBX64_RS06120	COG3956	TIGRFAM MazG family protein
DBX64_RS06140	COG0602	queuosine metabolic process
DBX64_RS06145	COG0720	synthase
DBX64_RS06165	COG2234	aminopeptidase activity
DBX64_RS06225	COG1388	LysM domain
DBX64_RS06225	COG4942	peptidase
DBX64_RS06230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DBX64_RS06255	COG0163	prenyltransferase activity
DBX64_RS06260	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DBX64_RS06355	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DBX64_RS06365	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DBX64_RS06405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX64_RS06410	COG4558	Periplasmic binding protein
DBX64_RS06415	COG3720	iron ion transport
DBX64_RS06435	COG0679	Auxin Efflux Carrier
DBX64_RS06450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBX64_RS06455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBX64_RS06460	COG1121	(ABC) transporter
DBX64_RS06470	COG1609	Transcriptional regulator
DBX64_RS06475	COG1940	carbohydrate kinase activity
DBX64_RS06480	COG1447	Phosphotransferase system cellobiose-specific component IIA
DBX64_RS06485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBX64_RS06490	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBX64_RS06495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBX64_RS06500	COG4580	involved in the transport of maltose and maltodextrins
DBX64_RS06510	COG2723	6-phospho-beta-galactosidase activity
DBX64_RS06520	COG0309	Hydrogenase expression formation protein (HypE)
DBX64_RS06525	COG0409	Hydrogenase expression formation protein
DBX64_RS06530	COG0298	carbon dioxide binding
DBX64_RS06535	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DBX64_RS06550	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DBX64_RS06555	COG0651	ATP synthesis coupled electron transport
DBX64_RS06560	COG0650	Formate hydrogenlyase subunit 4
DBX64_RS06565	COG3261	NADH dehydrogenase
DBX64_RS06565	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
DBX64_RS06570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DBX64_RS06575	COG3260	NADH ubiquinone oxidoreductase 20
DBX64_RS06585	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DBX64_RS06595	COG2723	6-phospho-beta-galactosidase activity
DBX64_RS06600	COG1263	PTS System
DBX64_RS06600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX64_RS06605	COG1609	Transcriptional regulator
DBX64_RS06610	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DBX64_RS06615	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DBX64_RS06620	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DBX64_RS06645	COG1349	DNA-binding transcription factor activity
DBX64_RS06650	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS06655	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS06665	COG3732	PTS system glucitol sorbitol-specific
DBX64_RS06670	COG3730	PTS system glucitol sorbitol-specific
DBX64_RS06675	COG2951	lytic endotransglycosylase activity
DBX64_RS06680	COG1121	(ABC) transporter
DBX64_RS06685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBX64_RS06695	COG1546	Belongs to the CinA family
DBX64_RS06715	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DBX64_RS06745	COG2823	Periplasmic or secreted lipoprotein
DBX64_RS06750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DBX64_RS06755	COG1238	metal cluster binding
DBX64_RS06775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DBX64_RS06780	COG2814	Major facilitator Superfamily
DBX64_RS06785	COG1566	PFAM secretion protein HlyD family protein
DBX64_RS06790	COG1846	Transcriptional regulator
DBX64_RS06800	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DBX64_RS06810	COG4176	ABC-type proline glycine betaine transport system permease component
DBX64_RS06825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DBX64_RS06835	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DBX64_RS06840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBX64_RS06845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBX64_RS06850	COG4575	ribosome binding
DBX64_RS06865	COG2916	Histone family protein nucleoid-structuring protein H-NS
DBX64_RS06880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DBX64_RS06885	COG0640	Transcriptional regulator
DBX64_RS06895	COG0583	DNA-binding transcription factor activity
DBX64_RS06900	COG3284	Transcriptional regulator
DBX64_RS06910	COG3539	Fimbrial protein
DBX64_RS06915	COG3121	Chaperone
DBX64_RS06935	COG3188	usher protein
DBX64_RS06950	COG2197	response regulator
DBX64_RS06965	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS06975	COG0235	Class ii aldolase
DBX64_RS06985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX64_RS07015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DBX64_RS07065	COG0431	NADPH-dependent FMN reductase
DBX64_RS07080	COG2271	Major facilitator Superfamily
DBX64_RS07085	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DBX64_RS07090	COG0477	Major facilitator Superfamily
DBX64_RS07095	COG3622	Belongs to the hyi family
DBX64_RS07120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX64_RS07125	COG2207	Transcriptional regulator
DBX64_RS07125	COG3708	Transcriptional regulator
DBX64_RS07155	COG2867	negative regulation of translational initiation
DBX64_RS07170	COG0497	DNA recombination
DBX64_RS07185	COG4536	flavin adenine dinucleotide binding
DBX64_RS07190	COG4137	Cytochrome C assembly protein
DBX64_RS07195	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DBX64_RS07230	COG2885	chlorophyll binding
DBX64_RS07235	COG2199	diguanylate cyclase activity
DBX64_RS07245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DBX64_RS07250	COG0287	Prephenate dehydrogenase
DBX64_RS07250	COG1605	Chorismate mutase
DBX64_RS07260	COG0077	Prephenate dehydratase
DBX64_RS07260	COG1605	Chorismate mutase
DBX64_RS07270	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DBX64_RS07275	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DBX64_RS07290	COG0542	response to heat
DBX64_RS07315	COG0477	Major facilitator Superfamily
DBX64_RS07320	COG5544	Lipoprotein
DBX64_RS07325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBX64_RS07335	COG3148	PFAM DTW domain containing protein
DBX64_RS07340	COG3118	belongs to the thioredoxin family
DBX64_RS07345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBX64_RS07360	COG0513	Belongs to the DEAD box helicase family
DBX64_RS07370	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DBX64_RS07385	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
DBX64_RS07390	COG3026	antisigma factor binding
DBX64_RS07395	COG3086	response to oxidative stress
DBX64_RS07405	COG0681	Belongs to the peptidase S26 family
DBX64_RS07425	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DBX64_RS07435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DBX64_RS07440	COG1737	Transcriptional regulator
DBX64_RS07445	COG0560	Phosphoserine phosphatase
DBX64_RS07460	COG0047	phosphoribosylformylglycinamidine synthase activity
DBX64_RS07460	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DBX64_RS07465	COG2205	protein histidine kinase activity
DBX64_RS07470	COG3170	Tfp pilus assembly protein FimV
DBX64_RS07475	COG2204	response regulator
DBX64_RS07480	COG0347	Belongs to the P(II) protein family
DBX64_RS07485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBX64_RS07485	COG1017	nitric oxide dioxygenase activity
DBX64_RS07495	COG2259	Doxx family
DBX64_RS07505	COG0457	Tetratricopeptide repeat
DBX64_RS07510	COG2814	Major facilitator Superfamily
DBX64_RS07510	COG0477	Major facilitator Superfamily
DBX64_RS07515	COG2017	converts alpha-aldose to the beta-anomer
DBX64_RS07520	COG2814	Major facilitator Superfamily
DBX64_RS07525	COG3711	transcriptional antiterminator
DBX64_RS07530	COG3683	transport system, periplasmic component
DBX64_RS07535	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
DBX64_RS07565	COG0822	iron-sulfur transferase activity
DBX64_RS07585	COG0633	Ferredoxin
DBX64_RS07590	COG2975	iron-sulfur cluster assembly
DBX64_RS07610	COG2897	thiosulfate sulfurtransferase activity
DBX64_RS07615	COG2373	Large extracellular alpha-helical protein
DBX64_RS07620	COG4953	penicillin-binding protein 1C
DBX64_RS07650	COG2976	Protein conserved in bacteria
DBX64_RS07670	COG1645	bacterial-type flagellum-dependent swarming motility
DBX64_RS07680	COG0517	IMP dehydrogenase activity
DBX64_RS07680	COG0516	GMP reductase activity
DBX64_RS07725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DBX64_RS07755	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DBX64_RS07760	COG3756	Protein conserved in bacteria
DBX64_RS07815	COG3728	DNA packaging
DBX64_RS07815	COG5484	DNA packaging
DBX64_RS07950	COG3119	arylsulfatase activity
DBX64_RS07955	COG0641	radical SAM
DBX64_RS07975	COG2200	EAL domain
DBX64_RS07990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DBX64_RS08005	COG2723	6-phospho-beta-galactosidase activity
DBX64_RS08015	COG2233	PERMEase
DBX64_RS08030	COG1393	Belongs to the ArsC family
DBX64_RS08035	COG4783	chaperone-mediated protein folding
DBX64_RS08045	COG0628	permease
DBX64_RS08050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DBX64_RS08055	COG2716	regulation of RNA biosynthetic process
DBX64_RS08065	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DBX64_RS08075	COG2321	neutral zinc metallopeptidase
DBX64_RS08080	COG1444	tRNA N-acetyltransferase activity
DBX64_RS08085	COG0400	carboxylic ester hydrolase activity
DBX64_RS08100	COG1393	Belongs to the ArsC family
DBX64_RS08110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DBX64_RS08115	COG0493	'glutamate synthase
DBX64_RS08115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DBX64_RS08125	COG5342	invasion associated locus B
DBX64_RS08130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DBX64_RS08135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DBX64_RS08145	COG4810	utilization protein
DBX64_RS08235	COG0860	N-Acetylmuramoyl-L-alanine amidase
DBX64_RS08255	COG2837	iron assimilation
DBX64_RS08265	COG4150	thiosulfate binding
DBX64_RS08270	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DBX64_RS08275	COG4208	sulfate ABC transporter
DBX64_RS08280	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DBX64_RS08290	COG4319	ketosteroid isomerase
DBX64_RS08325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DBX64_RS08345	COG3530	Putative quorum-sensing-regulated virulence factor
DBX64_RS08350	COG0385	Bile acid
DBX64_RS08355	COG0583	DNA-binding transcription factor activity
DBX64_RS08385	COG3415	Transposase
DBX64_RS08390	COG3415	Transposase
DBX64_RS08405	COG2200	EAL domain
DBX64_RS08405	COG2199	diguanylate cyclase activity
DBX64_RS08410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DBX64_RS08425	COG0667	Aldo Keto reductase
DBX64_RS08430	COG3961	Belongs to the TPP enzyme family
DBX64_RS08445	COG3279	Response regulator of the LytR AlgR family
DBX64_RS08450	COG3275	phosphorelay sensor kinase activity
DBX64_RS08465	COG0436	Aminotransferase
DBX64_RS08475	COG2807	transmembrane transport
DBX64_RS08480	COG0590	tRNA wobble adenosine to inosine editing
DBX64_RS08485	COG0583	DNA-binding transcription factor activity
DBX64_RS08505	COG2116	formate transmembrane transporter activity
DBX64_RS08510	COG2853	Lipoprotein
DBX64_RS08520	COG3691	Protein conserved in bacteria
DBX64_RS08535	COG2062	phosphohistidine phosphatase, SixA
DBX64_RS08560	COG0730	response to heat
DBX64_RS08565	COG3101	peptidyl-lysine hydroxylation
DBX64_RS08580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DBX64_RS08600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DBX64_RS08610	COG0586	Pfam SNARE associated Golgi protein
DBX64_RS08620	COG0285	dihydrofolate synthase activity
DBX64_RS08625	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
DBX64_RS08630	COG1286	toxin biosynthetic process
DBX64_RS08635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DBX64_RS08640	COG0163	prenyltransferase activity
DBX64_RS08665	COG4160	amino acid transport
DBX64_RS08670	COG4598	ABC transporter
DBX64_RS08685	COG1090	epimerase
DBX64_RS08690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DBX64_RS08695	COG0625	glutathione transferase activity
DBX64_RS08700	COG0625	glutathione transferase activity
DBX64_RS08705	COG0622	Phosphoesterase
DBX64_RS08710	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DBX64_RS08715	COG0857	belongs to the CobB CobQ family
DBX64_RS08715	COG0280	phosphate acetyltransferase
DBX64_RS08735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DBX64_RS08740	COG0471	metal ion transport
DBX64_RS08740	COG0490	domain, Protein
DBX64_RS08750	COG0436	Aminotransferase
DBX64_RS08755	COG0583	DNA-binding transcription factor activity
DBX64_RS08800	COG0839	Belongs to the complex I subunit 6 family
DBX64_RS08810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DBX64_RS08815	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DBX64_RS08830	COG2153	protein acetylation
DBX64_RS08835	COG1169	isochorismate synthase
DBX64_RS08860	COG0318	PFAM AMP-dependent synthetase and ligase
DBX64_RS08870	COG5464	transposase or invertase
DBX64_RS08885	COG1414	Transcriptional regulator
DBX64_RS08895	COG2271	Major facilitator Superfamily
DBX64_RS08905	COG0247	lactate metabolic process
DBX64_RS08915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DBX64_RS08920	COG2271	Major facilitator Superfamily
DBX64_RS08925	COG0584	glycerophosphoryl diester phosphodiesterase
DBX64_RS08930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBX64_RS08955	COG2205	protein histidine kinase activity
DBX64_RS08955	COG0784	Response regulator, receiver
DBX64_RS08965	COG0642	Histidine kinase
DBX64_RS08965	COG2198	Histidine kinase
DBX64_RS08980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DBX64_RS08980	COG2169	Transcriptional regulator
DBX64_RS08985	COG3145	DNA-N1-methyladenine dioxygenase activity
DBX64_RS08990	COG4615	Cyclic peptide transporter
DBX64_RS08995	COG2239	Acts as a magnesium transporter
DBX64_RS09000	COG0659	secondary active sulfate transmembrane transporter activity
DBX64_RS09015	COG0628	permease
DBX64_RS09040	COG1349	DNA-binding transcription factor activity
DBX64_RS09045	COG0494	nUDIX hydrolase
DBX64_RS09065	COG1061	Type III restriction enzyme res subunit
DBX64_RS09070	COG1187	pseudouridine synthase activity
DBX64_RS09075	COG2814	Major facilitator Superfamily
DBX64_RS09085	COG4172	Belongs to the ABC transporter superfamily
DBX64_RS09090	COG4239	(ABC) transporter, permease
DBX64_RS09095	COG4174	ABC transporter (Permease)
DBX64_RS09100	COG4166	transmembrane transport
DBX64_RS09105	COG2200	EAL domain
DBX64_RS09110	COG0791	NLP P60 protein
DBX64_RS09115	COG0671	phosphoesterase, PA-phosphatase related
DBX64_RS09120	COG0523	cobalamin synthesis protein
DBX64_RS09125	COG0246	Mannitol dehydrogenase
DBX64_RS09130	COG1312	Catalyzes the dehydration of D-mannonate
DBX64_RS09145	COG2814	Major facilitator Superfamily
DBX64_RS09150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS09150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS09155	COG1105	Belongs to the carbohydrate kinase PfkB family
DBX64_RS09160	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DBX64_RS09160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBX64_RS09160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBX64_RS09170	COG2855	membrane
DBX64_RS09175	COG0583	DNA-binding transcription factor activity
DBX64_RS09180	COG0833	amino acid
DBX64_RS09185	COG4771	TonB-dependent receptor
DBX64_RS09200	COG2311	Membrane
DBX64_RS09215	COG1129	ABC transporter
DBX64_RS09225	COG2949	membrane
DBX64_RS09235	COG1346	cytolysis
DBX64_RS09245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DBX64_RS09250	COG3659	wide pore channel activity
DBX64_RS09265	COG2723	6-phospho-beta-galactosidase activity
DBX64_RS09270	COG1538	Outer membrane efflux protein
DBX64_RS09275	COG0586	Pfam SNARE associated Golgi protein
DBX64_RS09285	COG1686	Belongs to the peptidase S11 family
DBX64_RS09300	COG0277	FAD linked oxidase domain protein
DBX64_RS09305	COG1472	Belongs to the glycosyl hydrolase 3 family
DBX64_RS09310	COG1732	Glycine betaine
DBX64_RS09315	COG1174	glycine betaine transport
DBX64_RS09320	COG1125	glycine betaine transport
DBX64_RS09325	COG1174	glycine betaine transport
DBX64_RS09335	COG3275	phosphorelay sensor kinase activity
DBX64_RS09345	COG4807	Protein conserved in bacteria
DBX64_RS09365	COG5455	response to cobalt ion
DBX64_RS09370	COG0583	DNA-binding transcription factor activity
DBX64_RS09375	COG2252	PERMEase
DBX64_RS09385	COG0583	DNA-binding transcription factor activity
DBX64_RS09390	COG2015	COG2015, Alkyl sulfatase and related hydrolases
DBX64_RS09425	COG0351	phosphomethylpyrimidine kinase
DBX64_RS09430	COG1830	Aldolase
DBX64_RS09465	COG1070	Carbohydrate kinase
DBX64_RS09475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DBX64_RS09480	COG4948	Mandelate Racemase Muconate Lactonizing
DBX64_RS09485	COG0747	negative chemotaxis
DBX64_RS09490	COG0601	transmembrane transport
DBX64_RS09495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX64_RS09500	COG0444	Belongs to the ABC transporter superfamily
DBX64_RS09505	COG4608	Belongs to the ABC transporter superfamily
DBX64_RS09515	COG0826	peptidase U32
DBX64_RS09520	COG0745	RESPONSE REGULATOR receiver
DBX64_RS09525	COG2205	protein histidine kinase activity
DBX64_RS09550	COG1301	dicarboxylic acid transport
DBX64_RS09570	COG5002	protein histidine kinase activity
DBX64_RS09575	COG0443	Heat shock 70 kDa protein
DBX64_RS09580	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DBX64_RS09595	COG2982	Protein involved in outer membrane biogenesis
DBX64_RS09600	COG1253	flavin adenine dinucleotide binding
DBX64_RS09655	COG0110	maltose O-acetyltransferase activity
DBX64_RS09660	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DBX64_RS09665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBX64_RS09670	COG1051	belongs to the nudix hydrolase family
DBX64_RS09675	COG0297	glycogen (starch) synthase activity
DBX64_RS09740	COG0438	transferase activity, transferring glycosyl groups
DBX64_RS09745	COG1216	Glycosyl transferase, family 2
DBX64_RS09745	COG1442	glycosyl transferase family 8
DBX64_RS09755	COG0463	Glycosyl transferase, family 2
DBX64_RS09780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DBX64_RS09810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBX64_RS09815	COG0583	DNA-binding transcription factor activity
DBX64_RS09825	COG0531	amino acid
DBX64_RS09830	COG0640	Transcriptional regulator
DBX64_RS09835	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DBX64_RS09840	COG2925	Exonuclease
DBX64_RS09850	COG3344	reverse transcriptase
DBX64_RS09860	COG1289	transmembrane transporter activity
DBX64_RS09880	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DBX64_RS09890	COG1942	4-Oxalocrotonate Tautomerase
DBX64_RS09895	COG0583	DNA-binding transcription factor activity
DBX64_RS09900	COG0095	Lipoate-protein ligase
DBX64_RS09905	COG0477	Major facilitator Superfamily
DBX64_RS09915	COG5001	Diguanylate cyclase
DBX64_RS09915	COG3300	MHYT domain
DBX64_RS09925	COG3615	Tellurite resistance protein tehB
DBX64_RS09950	COG3706	GGDEF domain
DBX64_RS09980	COG2197	response regulator
DBX64_RS09995	COG1250	3-hydroxyacyl-CoA dehydrogenase
DBX64_RS10000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBX64_RS10005	COG1960	acyl-CoA dehydrogenase activity
DBX64_RS10035	COG0154	amidase activity
DBX64_RS10060	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DBX64_RS10125	COG4771	TonB-dependent receptor
DBX64_RS10130	COG1021	2,3-dihydroxybenzoate-AMP ligase
DBX64_RS10150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBX64_RS10150	COG2226	methyltransferase
DBX64_RS10150	COG3433	isochorismatase activity
DBX64_RS10165	COG1132	(ABC) transporter
DBX64_RS10170	COG2814	Major facilitator Superfamily
DBX64_RS10175	COG1169	isochorismate synthase
DBX64_RS10180	COG0582	viral genome integration into host DNA
DBX64_RS10195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX64_RS10200	COG0735	belongs to the Fur family
DBX64_RS10210	COG0523	cobalamin synthesis protein
DBX64_RS10235	COG0523	cobalamin synthesis protein
DBX64_RS10265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBX64_RS10270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBX64_RS10275	COG1121	(ABC) transporter
DBX64_RS10280	COG0803	Belongs to the bacterial solute-binding protein 9 family
DBX64_RS10285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DBX64_RS10295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DBX64_RS10325	COG0803	Belongs to the bacterial solute-binding protein 9 family
DBX64_RS10330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBX64_RS10335	COG1121	(ABC) transporter
DBX64_RS10345	COG0582	viral genome integration into host DNA
DBX64_RS10355	COG0534	Mate efflux family protein
DBX64_RS10365	COG0582	viral genome integration into host DNA
DBX64_RS10400	COG4615	Cyclic peptide transporter
DBX64_RS10405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DBX64_RS10425	COG0604	alcohol dehydrogenase
DBX64_RS10430	COG1309	transcriptional regulator
DBX64_RS10435	COG0025	NhaP-type Na H and K H
DBX64_RS10455	COG1376	ErfK ybiS ycfS ynhG family protein
DBX64_RS10470	COG0251	oxidation-reduction process
DBX64_RS10490	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DBX64_RS10500	COG1418	mRNA catabolic process
DBX64_RS10505	COG0270	DNA (cytosine-5-)-methyltransferase activity
DBX64_RS10510	COG3727	T/G mismatch-specific endonuclease activity
DBX64_RS10515	COG0697	spore germination
DBX64_RS10520	COG2354	Protein conserved in bacteria
DBX64_RS10550	COG0366	Alpha amylase catalytic
DBX64_RS10555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX64_RS10565	COG0765	amino acid transport
DBX64_RS10570	COG1126	abc transporter atp-binding protein
DBX64_RS10575	COG2197	response regulator
DBX64_RS10585	COG2197	response regulator
DBX64_RS10620	COG3318	Belongs to the UPF0149 family
DBX64_RS10620	COG3012	SEC-C Motif Domain Protein
DBX64_RS10625	COG0814	amino acid
DBX64_RS10635	COG1528	Iron-storage protein
DBX64_RS10650	COG0477	Major facilitator Superfamily
DBX64_RS10660	COG2211	Major facilitator Superfamily
DBX64_RS10670	COG1528	Iron-storage protein
DBX64_RS10680	COG1879	ABC-type sugar transport system periplasmic component
DBX64_RS10690	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS10715	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DBX64_RS10725	COG3102	Protein conserved in bacteria
DBX64_RS10745	COG3788	relative of glutathione S-transferase, MAPEG superfamily
DBX64_RS10750	COG1801	Protein of unknown function DUF72
DBX64_RS10755	COG1335	isochorismatase
DBX64_RS10765	COG0494	nUDIX hydrolase
DBX64_RS10790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBX64_RS10800	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
DBX64_RS10805	COG0739	heme binding
DBX64_RS10810	COG1560	Kdo2-lipid A biosynthetic process
DBX64_RS10820	COG1737	Transcriptional regulator
DBX64_RS10830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DBX64_RS10835	COG0129	dihydroxy-acid dehydratase activity
DBX64_RS10840	COG0800	Aldolase
DBX64_RS10850	COG3141	response to X-ray
DBX64_RS10855	COG2979	Protein of unknown function (DUF533)
DBX64_RS10860	COG1770	oligopeptidase
DBX64_RS10865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DBX64_RS10875	COG2372	response to copper ion
DBX64_RS10880	COG1276	copper resistance
DBX64_RS10895	COG2990	Protein conserved in bacteria
DBX64_RS10920	COG3008	intermembrane lipid transfer
DBX64_RS10925	COG2995	paraquat-inducible protein a
DBX64_RS10930	COG1956	GAF domain-containing protein
DBX64_RS10950	COG2814	Major facilitator Superfamily
DBX64_RS10955	COG1414	Transcriptional regulator
DBX64_RS10985	COG0768	penicillin binding
DBX64_RS10990	COG2226	methyltransferase
DBX64_RS11005	COG3716	PTS system mannose fructose sorbose family IID component
DBX64_RS11010	COG3715	PTS system
DBX64_RS11015	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS11015	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX64_RS11020	COG1253	flavin adenine dinucleotide binding
DBX64_RS11025	COG2200	EAL domain
DBX64_RS11030	COG1760	l-serine dehydratase
DBX64_RS11050	COG0251	oxidation-reduction process
DBX64_RS11055	COG1199	ATP-dependent helicase activity
DBX64_RS11065	COG3065	identical protein binding
DBX64_RS11075	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DBX64_RS11085	COG2894	cell division
DBX64_RS11100	COG0179	Fumarylacetoacetate (FAA) hydrolase
DBX64_RS11130	COG2719	SpoVR family
DBX64_RS11155	COG1619	proteins homologs of microcin C7 resistance protein MccF
DBX64_RS11165	COG4774	siderophore transport
DBX64_RS11180	COG2308	Evidence 4 Homologs of previously reported genes of
DBX64_RS11225	COG0583	DNA-binding transcription factor activity
DBX64_RS11230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DBX64_RS11245	COG1882	Formate acetyltransferase
DBX64_RS11280	COG0583	DNA-binding transcription factor activity
DBX64_RS11310	COG0583	DNA-binding transcription factor activity
DBX64_RS11325	COG3122	Protein conserved in bacteria
DBX64_RS11345	COG2885	chlorophyll binding
DBX64_RS11375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DBX64_RS11390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DBX64_RS11455	COG0012	GTP binding
DBX64_RS11475	COG0659	secondary active sulfate transmembrane transporter activity
DBX64_RS11505	COG2890	protein-(glutamine-N5) methyltransferase activity
DBX64_RS11525	COG0387	Pfam Sodium calcium exchanger
DBX64_RS11530	COG4572	Cation transport regulator
DBX64_RS11535	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DBX64_RS11545	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DBX64_RS11550	COG3707	response regulator
DBX64_RS11555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DBX64_RS11565	COG1116	anion transmembrane transporter activity
DBX64_RS11570	COG2146	nitrite reductase [NAD(P)H] activity
DBX64_RS11570	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DBX64_RS11575	COG0243	molybdopterin cofactor binding
DBX64_RS11580	COG4932	domain protein
DBX64_RS11585	COG2197	response regulator
DBX64_RS11590	COG3850	Histidine kinase
DBX64_RS11595	COG2223	nitrite transmembrane transporter activity
DBX64_RS11605	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DBX64_RS11610	COG1140	nitrate reductase beta subunit
DBX64_RS11615	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DBX64_RS11620	COG2181	nitrate reductase activity
DBX64_RS11630	COG1522	sequence-specific DNA binding
DBX64_RS11665	COG0788	formyltetrahydrofolate deformylase activity
DBX64_RS11675	COG1752	Esterase of the alpha-beta hydrolase superfamily
DBX64_RS11680	COG0745	RESPONSE REGULATOR receiver
DBX64_RS11685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DBX64_RS11690	COG2916	Histone family protein nucleoid-structuring protein H-NS
DBX64_RS11700	COG1435	thymidine kinase activity
DBX64_RS11705	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS11705	COG1454	alcohol dehydrogenase
DBX64_RS11715	COG2095	MarC family integral membrane protein
DBX64_RS11720	COG4166	transmembrane transport
DBX64_RS11725	COG0601	transmembrane transport
DBX64_RS11730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX64_RS11735	COG0444	Belongs to the ABC transporter superfamily
DBX64_RS11745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DBX64_RS11765	COG2353	YceI-like domain
DBX64_RS11775	COG2350	Protein conserved in bacteria
DBX64_RS11785	COG3001	Fructosamine kinase
DBX64_RS11795	COG1105	Belongs to the carbohydrate kinase PfkB family
DBX64_RS11800	COG3137	Salt-induced outer membrane protein
DBX64_RS11840	COG0072	phenylalanine-tRNA ligase activity
DBX64_RS11840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBX64_RS11860	COG0583	DNA-binding transcription factor activity
DBX64_RS11880	COG0386	Belongs to the glutathione peroxidase family
DBX64_RS11890	COG0791	NLP P60 protein
DBX64_RS11900	COG4256	Hemin uptake protein
DBX64_RS11905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DBX64_RS11920	COG0574	Belongs to the PEP-utilizing enzyme family
DBX64_RS11920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DBX64_RS11930	COG0628	permease
DBX64_RS11935	COG0277	FAD linked oxidase domain protein
DBX64_RS11935	COG0247	lactate metabolic process
DBX64_RS11940	COG2050	protein possibly involved in aromatic compounds catabolism
DBX64_RS11945	COG2261	transglycosylase associated protein
DBX64_RS11970	COG1120	ATPase activity
DBX64_RS11975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX64_RS11985	COG0583	DNA-binding transcription factor activity
DBX64_RS12010	COG1304	FMN binding
DBX64_RS12015	COG1309	transcriptional regulator
DBX64_RS12035	COG0316	Belongs to the HesB IscA family
DBX64_RS12040	COG0719	Fe-S assembly protein
DBX64_RS12045	COG0396	ATPase activity
DBX64_RS12050	COG0719	Fe-S assembly protein
DBX64_RS12065	COG1376	ErfK ybiS ycfS ynhG family protein
DBX64_RS12095	COG1309	transcriptional regulator
DBX64_RS12100	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DBX64_RS12100	COG1082	Xylose isomerase domain protein TIM barrel
DBX64_RS12105	COG2271	Major facilitator Superfamily
DBX64_RS12110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DBX64_RS12120	COG1120	ATPase activity
DBX64_RS12125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX64_RS12130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DBX64_RS12135	COG1414	Transcriptional regulator
DBX64_RS12170	COG2814	Major facilitator Superfamily
DBX64_RS12190	COG0583	DNA-binding transcription factor activity
DBX64_RS12195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBX64_RS12215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DBX64_RS12220	COG1116	anion transmembrane transporter activity
DBX64_RS12225	COG4774	siderophore transport
DBX64_RS12230	COG1120	ATPase activity
DBX64_RS12235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX64_RS12240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX64_RS12260	COG0765	amino acid transport
DBX64_RS12265	COG1126	abc transporter atp-binding protein
DBX64_RS12305	COG3383	formate dehydrogenase (NAD+) activity
DBX64_RS12310	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DBX64_RS12320	COG1175	transmembrane transport
DBX64_RS12350	COG1857	crispr-associated protein
DBX64_RS12360	COG1518	maintenance of DNA repeat elements
DBX64_RS12365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DBX64_RS12370	COG3157	Type VI secretion system effector, Hcp
DBX64_RS12400	COG4133	protoheme IX ABC transporter activity
DBX64_RS12405	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DBX64_RS12410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DBX64_RS12425	COG1138	Cytochrome C-type biogenesis protein
DBX64_RS12430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBX64_RS12435	COG4235	cytochrome complex assembly
DBX64_RS12435	COG3088	subunit of a heme lyase
DBX64_RS12485	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS12490	COG2610	gluconate transmembrane transporter activity
DBX64_RS12495	COG1250	3-hydroxyacyl-CoA dehydrogenase
DBX64_RS12505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DBX64_RS12515	COG0583	DNA-binding transcription factor activity
DBX64_RS12540	COG0277	FAD linked oxidase domain protein
DBX64_RS12545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DBX64_RS12575	COG0402	S-adenosylhomocysteine deaminase activity
DBX64_RS12630	COG4608	Belongs to the ABC transporter superfamily
DBX64_RS12635	COG0444	Belongs to the ABC transporter superfamily
DBX64_RS12660	COG0346	lactoylglutathione lyase activity
DBX64_RS12665	COG1349	DNA-binding transcription factor activity
DBX64_RS12700	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DBX64_RS12720	COG0300	oxidoreductase activity
DBX64_RS12765	COG0307	riboflavin synthase, alpha
DBX64_RS12770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DBX64_RS12775	COG2814	Major facilitator Superfamily
DBX64_RS12780	COG0583	DNA-binding transcription factor activity
DBX64_RS12795	COG2814	Major facilitator Superfamily
DBX64_RS12810	COG0791	NLP P60 protein
DBX64_RS12815	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DBX64_RS12825	COG0346	lactoylglutathione lyase activity
DBX64_RS12830	COG1902	pentaerythritol trinitrate reductase activity
DBX64_RS12835	COG1309	transcriptional regulator
DBX64_RS12840	COG3313	Fe-S protein
DBX64_RS12845	COG4989	oxidoreductase activity
DBX64_RS12850	COG2032	superoxide dismutase activity
DBX64_RS12855	COG1289	transmembrane transporter activity
DBX64_RS12860	COG1566	PFAM secretion protein HlyD family protein
DBX64_RS12875	COG3706	GGDEF domain
DBX64_RS12890	COG3895	Periplasmic Protein
DBX64_RS12905	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DBX64_RS12910	COG0625	glutathione transferase activity
DBX64_RS12920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DBX64_RS12930	COG4659	FMN binding
DBX64_RS12965	COG2723	6-phospho-beta-galactosidase activity
DBX64_RS12975	COG0673	inositol 2-dehydrogenase activity
DBX64_RS12985	COG2814	Major facilitator Superfamily
DBX64_RS13005	COG3038	cytochrome b561
DBX64_RS13025	COG0583	DNA-binding transcription factor activity
DBX64_RS13030	COG3485	protocatechuate 3,4-dioxygenase
DBX64_RS13035	COG3485	protocatechuate 3,4-dioxygenase
DBX64_RS13040	COG5383	Protein conserved in bacteria
DBX64_RS13045	COG2272	Belongs to the type-B carboxylesterase lipase family
DBX64_RS13060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBX64_RS13065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DBX64_RS13070	COG1275	C4-dicarboxylate transporter malic acid transport protein
DBX64_RS13075	COG0500	methyltransferase
DBX64_RS13085	COG0697	spore germination
DBX64_RS13090	COG2207	Transcriptional regulator
DBX64_RS13090	COG3708	Transcriptional regulator
DBX64_RS13095	COG3135	benzoate transporter
DBX64_RS13100	COG1396	sequence-specific DNA binding
DBX64_RS13110	COG0826	peptidase U32
DBX64_RS13130	COG1294	oxidase, subunit
DBX64_RS13135	COG1271	oxidase subunit
DBX64_RS13140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBX64_RS13145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DBX64_RS13150	COG3842	ATPase activity
DBX64_RS13155	COG1176	ABC-type spermidine putrescine transport system, permease component I
DBX64_RS13160	COG1177	transmembrane transport
DBX64_RS13165	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS13200	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS13205	COG0747	negative chemotaxis
DBX64_RS13215	COG3238	Protein conserved in bacteria
DBX64_RS13220	COG1247	-acetyltransferase
DBX64_RS13230	COG2130	NADP-dependent
DBX64_RS13245	COG3691	Protein conserved in bacteria
DBX64_RS13250	COG1228	amidohydrolase
DBX64_RS13255	COG4772	TonB-dependent receptor
DBX64_RS13280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DBX64_RS13285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBX64_RS13290	COG1473	amidohydrolase
DBX64_RS13295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBX64_RS13300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX64_RS13310	COG0765	amino acid transport
DBX64_RS13315	COG1126	abc transporter atp-binding protein
DBX64_RS13325	COG0625	glutathione transferase activity
DBX64_RS13335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DBX64_RS13340	COG3842	ATPase activity
DBX64_RS13345	COG1840	ABC-type Fe3 transport system, periplasmic component
DBX64_RS13350	COG1178	ABC-type Fe3 transport system permease component
DBX64_RS13355	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DBX64_RS13360	COG2181	nitrate reductase activity
DBX64_RS13365	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DBX64_RS13370	COG1140	nitrate reductase beta subunit
DBX64_RS13375	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DBX64_RS13380	COG2223	nitrite transmembrane transporter activity
DBX64_RS13395	COG1414	Transcriptional regulator
DBX64_RS13400	COG4948	Mandelate Racemase Muconate Lactonizing
DBX64_RS13405	COG4829	muconolactone delta-isomerase
DBX64_RS13410	COG3485	protocatechuate 3,4-dioxygenase
DBX64_RS13420	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DBX64_RS13445	COG0437	4 iron, 4 sulfur cluster binding
DBX64_RS13450	COG2864	formate dehydrogenase
DBX64_RS13465	COG2326	polyphosphate kinase activity
DBX64_RS13475	COG2814	Major facilitator Superfamily
DBX64_RS13485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBX64_RS13495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX64_RS13505	COG0747	negative chemotaxis
DBX64_RS13510	COG1064	alcohol dehydrogenase
DBX64_RS13525	COG0488	(ABC) transporter
DBX64_RS13565	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS13570	COG3729	General stress protein
DBX64_RS13580	COG3685	Protein conserved in bacteria
DBX64_RS13590	COG0366	Alpha amylase catalytic
DBX64_RS13600	COG2323	membrane
DBX64_RS13610	COG3111	PFAM Bacterial OB fold (BOF) protein
DBX64_RS13620	COG1764	response to oxidative stress
DBX64_RS13645	COG3781	membrane
DBX64_RS13650	COG0243	molybdopterin cofactor binding
DBX64_RS13655	COG0583	DNA-binding transcription factor activity
DBX64_RS13685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBX64_RS13690	COG1447	Phosphotransferase system cellobiose-specific component IIA
DBX64_RS13695	COG2814	Major facilitator Superfamily
DBX64_RS13700	COG1285	pathogenesis
DBX64_RS13705	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DBX64_RS13715	COG0583	DNA-binding transcription factor activity
DBX64_RS13735	COG0519	Catalyzes the synthesis of GMP from XMP
DBX64_RS13735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DBX64_RS13775	COG0596	Alpha beta hydrolase
DBX64_RS13785	COG2205	protein histidine kinase activity
DBX64_RS13800	COG0076	glutamate decarboxylase activity
DBX64_RS13805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DBX64_RS13810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DBX64_RS13815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DBX64_RS13820	COG1116	anion transmembrane transporter activity
DBX64_RS13825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DBX64_RS13840	COG0673	inositol 2-dehydrogenase activity
DBX64_RS13850	COG1609	Transcriptional regulator
DBX64_RS13855	COG3706	GGDEF domain
DBX64_RS13860	COG0402	S-adenosylhomocysteine deaminase activity
DBX64_RS13865	COG1953	Uracil, thiamine, allantoin
DBX64_RS13900	COG0596	Alpha beta hydrolase
DBX64_RS13910	COG2207	Transcriptional regulator
DBX64_RS13925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DBX64_RS13950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DBX64_RS13995	COG0765	amino acid transport
DBX64_RS14005	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DBX64_RS14015	COG2070	2-Nitropropane dioxygenase
DBX64_RS14020	COG0583	DNA-binding transcription factor activity
DBX64_RS14030	COG1902	pentaerythritol trinitrate reductase activity
DBX64_RS14035	COG4529	Protein conserved in bacteria
DBX64_RS14040	COG0477	Major facilitator Superfamily
DBX64_RS14070	COG2223	nitrite transmembrane transporter activity
DBX64_RS14080	COG1609	Transcriptional regulator
DBX64_RS14085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS14095	COG3037	sugar-specific permease SgaT UlaA
DBX64_RS14100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DBX64_RS14110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBX64_RS14130	COG0583	DNA-binding transcription factor activity
DBX64_RS14135	COG0583	DNA-binding transcription factor activity
DBX64_RS14140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBX64_RS14150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DBX64_RS14165	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS14175	COG1609	Transcriptional regulator
DBX64_RS14205	COG1652	LysM domain
DBX64_RS14230	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DBX64_RS14230	COG0456	acetyltransferase
DBX64_RS14255	COG1349	DNA-binding transcription factor activity
DBX64_RS14270	COG1349	DNA-binding transcription factor activity
DBX64_RS14275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DBX64_RS14280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX64_RS14285	COG0738	Major facilitator superfamily
DBX64_RS14330	COG1929	Belongs to the glycerate kinase type-1 family
DBX64_RS14335	COG3835	regulator
DBX64_RS14355	COG2186	Transcriptional regulator
DBX64_RS14360	COG1263	PTS System
DBX64_RS14360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX64_RS14370	COG2814	Major facilitator Superfamily
DBX64_RS14375	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS14375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS14390	COG2819	hydrolase of the alpha beta superfamily
DBX64_RS14395	COG5001	Diguanylate cyclase
DBX64_RS14395	COG3300	MHYT domain
DBX64_RS14430	COG3188	usher protein
DBX64_RS14440	COG1649	PFAM Uncharacterised BCR, COG1649
DBX64_RS14445	COG3550	peptidyl-serine autophosphorylation
DBX64_RS14450	COG1396	sequence-specific DNA binding
DBX64_RS14455	COG2351	hydroxyisourate hydrolase activity
DBX64_RS14460	COG3195	allantoin biosynthetic process
DBX64_RS14460	COG3648	Uricase
DBX64_RS14465	COG2233	PERMEase
DBX64_RS14495	COG2207	Transcriptional regulator
DBX64_RS14530	COG2011	ABC-type metal ion transport system permease component
DBX64_RS14535	COG2070	2-Nitropropane dioxygenase
DBX64_RS14545	COG0477	Major facilitator Superfamily
DBX64_RS14620	COG2199	diguanylate cyclase activity
DBX64_RS14635	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS14640	COG0583	DNA-binding transcription factor activity
DBX64_RS14650	COG0039	L-malate dehydrogenase activity
DBX64_RS14655	COG1349	DNA-binding transcription factor activity
DBX64_RS14660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DBX64_RS14665	COG3395	kinase activity
DBX64_RS14675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DBX64_RS14680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBX64_RS14685	COG2271	Major facilitator Superfamily
DBX64_RS14715	COG4977	sequence-specific DNA binding
DBX64_RS14725	COG0697	spore germination
DBX64_RS14730	COG2814	Major facilitator Superfamily
DBX64_RS14745	COG1129	ABC transporter
DBX64_RS14765	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DBX64_RS14800	COG2223	nitrite transmembrane transporter activity
DBX64_RS14805	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DBX64_RS14820	COG1349	DNA-binding transcription factor activity
DBX64_RS14825	COG2084	Dehydrogenase
DBX64_RS14830	COG3395	kinase activity
DBX64_RS14835	COG0235	Class ii aldolase
DBX64_RS14840	COG3622	Belongs to the hyi family
DBX64_RS14845	COG2610	gluconate transmembrane transporter activity
DBX64_RS14850	COG2207	Transcriptional regulator
DBX64_RS14850	COG3708	Transcriptional regulator
DBX64_RS14865	COG2200	EAL domain
DBX64_RS14870	COG1546	Belongs to the CinA family
DBX64_RS14875	COG0071	Belongs to the small heat shock protein (HSP20) family
DBX64_RS14890	COG2197	response regulator
DBX64_RS14905	COG2135	peptidase activity
DBX64_RS14910	COG2207	Transcriptional regulator
DBX64_RS14925	COG4221	oxidoreductase activity
DBX64_RS14930	COG1802	Transcriptional regulator
DBX64_RS14935	COG0589	response to stress
DBX64_RS14940	COG0246	Mannitol dehydrogenase
DBX64_RS14945	COG2271	Major facilitator Superfamily
DBX64_RS14960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBX64_RS14975	COG0243	molybdopterin cofactor binding
DBX64_RS14980	COG0437	4 iron, 4 sulfur cluster binding
DBX64_RS14985	COG3302	dmso reductase anchor subunit
DBX64_RS15000	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DBX64_RS15005	COG1940	carbohydrate kinase activity
DBX64_RS15010	COG0583	DNA-binding transcription factor activity
DBX64_RS15015	COG2814	Major facilitator Superfamily
DBX64_RS15020	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DBX64_RS15030	COG3591	Belongs to the peptidase S1B family
DBX64_RS15050	COG0628	permease
DBX64_RS15080	COG0679	Auxin Efflux Carrier
DBX64_RS15090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DBX64_RS15135	COG3290	protein histidine kinase activity
DBX64_RS15140	COG4565	transcriptional regulatory protein
DBX64_RS15160	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DBX64_RS15160	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DBX64_RS15170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBX64_RS15175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DBX64_RS15185	COG0183	Belongs to the thiolase family
DBX64_RS15190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DBX64_RS15200	COG1414	Transcriptional regulator
DBX64_RS15205	COG2840	Smr protein MutS2
DBX64_RS15210	COG0583	DNA-binding transcription factor activity
DBX64_RS15220	COG1473	amidohydrolase
DBX64_RS15225	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DBX64_RS15240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DBX64_RS15255	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DBX64_RS15260	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DBX64_RS15275	COG0531	amino acid
DBX64_RS15285	COG3136	membrane protein required for alginate biosynthesis
DBX64_RS15290	COG0745	RESPONSE REGULATOR receiver
DBX64_RS15300	COG2205	protein histidine kinase activity
DBX64_RS15310	COG0114	fumarate hydratase activity
DBX64_RS15315	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DBX64_RS15315	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DBX64_RS15320	COG1482	cell wall glycoprotein biosynthetic process
DBX64_RS15325	COG5339	Protein conserved in bacteria
DBX64_RS15330	COG1609	Transcriptional regulator
DBX64_RS15335	COG1263	PTS System
DBX64_RS15335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX64_RS15340	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DBX64_RS15365	COG2391	methyltransferase activity
DBX64_RS15370	COG0425	Belongs to the sulfur carrier protein TusA family
DBX64_RS15375	COG5562	phage envelope protein
DBX64_RS15380	COG0401	homolog of Blt101
DBX64_RS15385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DBX64_RS15390	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS15400	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DBX64_RS15405	COG0477	Major facilitator Superfamily
DBX64_RS15410	COG1113	amino acid transport
DBX64_RS15415	COG2988	succinylglutamate desuccinylase activity
DBX64_RS15420	COG3724	N-succinylarginine dihydrolase activity
DBX64_RS15425	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS15430	COG3138	arginine N-succinyltransferase
DBX64_RS15435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DBX64_RS15445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DBX64_RS15450	COG0667	Aldo Keto reductase
DBX64_RS15455	COG0583	DNA-binding transcription factor activity
DBX64_RS15480	COG4122	O-methyltransferase activity
DBX64_RS15485	COG1643	Atp-dependent helicase
DBX64_RS15500	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DBX64_RS15505	COG3327	negative regulation of DNA-templated transcription, initiation
DBX64_RS15510	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DBX64_RS15515	COG0183	Belongs to the thiolase family
DBX64_RS15520	COG2050	protein possibly involved in aromatic compounds catabolism
DBX64_RS15525	COG1250	3-hydroxyacyl-CoA dehydrogenase
DBX64_RS15530	COG1024	Enoyl-CoA hydratase
DBX64_RS15535	COG1024	Enoyl-CoA hydratase
DBX64_RS15540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBX64_RS15545	COG2151	metal-sulfur cluster biosynthetic enzyme
DBX64_RS15550	COG3396	Phenylacetate-CoA oxygenase
DBX64_RS15555	COG3460	Phenylacetate-CoA oxygenase
DBX64_RS15560	COG3396	Phenylacetate-CoA oxygenase
DBX64_RS15565	COG2030	dehydratase
DBX64_RS15565	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS15585	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS15590	COG2207	Transcriptional regulator
DBX64_RS15595	COG3784	Protein of unknown function (DUF1318)
DBX64_RS15605	COG2911	Protein conserved in bacteria
DBX64_RS15610	COG0586	Pfam SNARE associated Golgi protein
DBX64_RS15615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBX64_RS15620	COG3187	Heat shock protein
DBX64_RS15625	COG3042	response to heat
DBX64_RS15630	COG1013	pyruvate-flavodoxin oxidoreductase activity
DBX64_RS15630	COG0674	pyruvate-flavodoxin oxidoreductase activity
DBX64_RS15630	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DBX64_RS15630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DBX64_RS15635	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DBX64_RS15645	COG0589	response to stress
DBX64_RS15655	COG0513	Belongs to the DEAD box helicase family
DBX64_RS15665	COG1349	DNA-binding transcription factor activity
DBX64_RS15670	COG0673	inositol 2-dehydrogenase activity
DBX64_RS15685	COG1113	amino acid transport
DBX64_RS15690	COG1522	sequence-specific DNA binding
DBX64_RS15700	COG1448	Aminotransferase
DBX64_RS15705	COG2011	ABC-type metal ion transport system permease component
DBX64_RS15720	COG0436	Aminotransferase
DBX64_RS15725	COG0604	alcohol dehydrogenase
DBX64_RS15755	COG0583	DNA-binding transcription factor activity
DBX64_RS15775	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS15780	COG1309	transcriptional regulator
DBX64_RS15785	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS15845	COG2801	Transposase and inactivated derivatives
DBX64_RS15850	COG2963	transposase activity
DBX64_RS15855	COG2963	transposase activity
DBX64_RS15865	COG1705	Flagellar rod assembly protein muramidase FlgJ
DBX64_RS15865	COG1388	LysM domain
DBX64_RS15890	COG2885	chlorophyll binding
DBX64_RS15915	COG0693	protein deglycase activity
DBX64_RS15920	COG1078	dGTPase activity
DBX64_RS15925	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS15930	COG0583	DNA-binding transcription factor activity
DBX64_RS15990	COG0784	Response regulator, receiver
DBX64_RS15990	COG5002	protein histidine kinase activity
DBX64_RS15990	COG2205	protein histidine kinase activity
DBX64_RS15995	COG3250	beta-galactosidase activity
DBX64_RS16000	COG0656	L-ascorbic acid biosynthetic process
DBX64_RS16070	COG4166	transmembrane transport
DBX64_RS16080	COG2866	Carboxypeptidase
DBX64_RS16085	COG4948	Mandelate Racemase Muconate Lactonizing
DBX64_RS16090	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DBX64_RS16095	COG3180	Ammonia monooxygenase
DBX64_RS16105	COG1486	melibiose metabolic process
DBX64_RS16110	COG0583	DNA-binding transcription factor activity
DBX64_RS16120	COG3106	COG3106 Predicted ATPase
DBX64_RS16130	COG1983	PspC domain protein
DBX64_RS16140	COG1842	Phage shock protein A
DBX64_RS16145	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DBX64_RS16155	COG1473	amidohydrolase
DBX64_RS16170	COG0702	epimerase
DBX64_RS16200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DBX64_RS16205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DBX64_RS16210	COG3344	reverse transcriptase
DBX64_RS16325	COG4695	Portal protein
DBX64_RS16330	COG1802	Transcriptional regulator
DBX64_RS16330	COG4626	Terminase
DBX64_RS16405	COG0484	heat shock protein binding
DBX64_RS16410	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DBX64_RS16475	COG1484	DNA-dependent DNA replication
DBX64_RS16540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DBX64_RS16560	COG4171	peptide transport system, permease
DBX64_RS16575	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DBX64_RS16585	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DBX64_RS16590	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBX64_RS16590	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBX64_RS16605	COG1349	DNA-binding transcription factor activity
DBX64_RS16615	COG0023	Translation Initiation Factor
DBX64_RS16625	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DBX64_RS16630	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
DBX64_RS16635	COG0671	phosphoesterase, PA-phosphatase related
DBX64_RS16645	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DBX64_RS16670	COG0616	signal peptide processing
DBX64_RS16680	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS16685	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
DBX64_RS16695	COG0583	DNA-binding transcription factor activity
DBX64_RS16705	COG0009	L-threonylcarbamoyladenylate synthase
DBX64_RS16715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DBX64_RS16720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DBX64_RS16720	COG0512	Glutamine amidotransferase of anthranilate synthase
DBX64_RS16725	COG0135	phosphoribosylanthranilate isomerase activity
DBX64_RS16725	COG0134	indole-3-glycerol-phosphate synthase activity
DBX64_RS16780	COG4774	siderophore transport
DBX64_RS16790	COG3047	cAMP biosynthetic process
DBX64_RS16795	COG0727	PFAM Uncharacterised protein family (UPF0153)
DBX64_RS16825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DBX64_RS16830	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS16835	COG1988	membrane-bound metal-dependent
DBX64_RS16840	COG1823	symporter activity
DBX64_RS16850	COG0753	catalase activity
DBX64_RS16860	COG1486	melibiose metabolic process
DBX64_RS16865	COG2169	Transcriptional regulator
DBX64_RS16865	COG1917	Cupin 2, conserved barrel domain protein
DBX64_RS16870	COG1447	Phosphotransferase system cellobiose-specific component IIA
DBX64_RS16875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBX64_RS16885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBX64_RS16890	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DBX64_RS16900	COG0322	excinuclease ABC activity
DBX64_RS16905	COG3678	ATP-independent chaperone mediated protein folding
DBX64_RS16915	COG3724	N-succinylarginine dihydrolase activity
DBX64_RS16925	COG3138	arginine N-succinyltransferase
DBX64_RS16935	COG0708	Exodeoxyribonuclease III
DBX64_RS16940	COG0398	Pfam SNARE associated Golgi protein
DBX64_RS16945	COG0398	Pfam SNARE associated Golgi protein
DBX64_RS16950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBX64_RS16955	COG4134	Bacterial extracellular solute-binding protein
DBX64_RS16960	COG4135	transport system, permease component
DBX64_RS16965	COG4136	ATPase activity
DBX64_RS16970	COG2897	thiosulfate sulfurtransferase activity
DBX64_RS16975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DBX64_RS16980	COG0494	nUDIX hydrolase
DBX64_RS16985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DBX64_RS16990	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS16990	COG0604	alcohol dehydrogenase
DBX64_RS16990	COG3321	synthase
DBX64_RS16995	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DBX64_RS17000	COG0709	Synthesizes selenophosphate from selenide and ATP
DBX64_RS17010	COG0778	Nitroreductase
DBX64_RS17015	COG0616	signal peptide processing
DBX64_RS17020	COG0252	asparaginase activity
DBX64_RS17025	COG1335	isochorismatase
DBX64_RS17040	COG3139	Protein of unknown function (DUF1315)
DBX64_RS17060	COG0656	L-ascorbic acid biosynthetic process
DBX64_RS17065	COG3713	MltA-interacting MipA family protein
DBX64_RS17070	COG2766	serine protein kinase
DBX64_RS17085	COG0386	Belongs to the glutathione peroxidase family
DBX64_RS17110	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS17115	COG0583	DNA-binding transcription factor activity
DBX64_RS17120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DBX64_RS17125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DBX64_RS17130	COG3344	reverse transcriptase
DBX64_RS17140	COG0859	PFAM glycosyl transferase family 9
DBX64_RS17145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DBX64_RS17155	COG2207	Transcriptional regulator
DBX64_RS17160	COG2807	transmembrane transport
DBX64_RS17165	COG0504	CTP synthase activity
DBX64_RS17170	COG1683	Conserved Protein
DBX64_RS17175	COG3189	MarR family transcriptional regulator
DBX64_RS17180	COG3042	response to heat
DBX64_RS17185	COG2203	Gaf domain
DBX64_RS17185	COG2199	diguanylate cyclase activity
DBX64_RS17205	COG3182	Iron-regulated membrane protein
DBX64_RS17215	COG1560	Kdo2-lipid A biosynthetic process
DBX64_RS17225	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DBX64_RS17230	COG3706	GGDEF domain
DBX64_RS17235	COG0583	DNA-binding transcription factor activity
DBX64_RS17240	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DBX64_RS17270	COG1294	oxidase, subunit
DBX64_RS17275	COG1271	oxidase subunit
DBX64_RS17280	COG3546	catalase activity
DBX64_RS17285	COG3685	Protein conserved in bacteria
DBX64_RS17290	COG3685	Protein conserved in bacteria
DBX64_RS17295	COG3729	General stress protein
DBX64_RS17305	COG1063	alcohol dehydrogenase
DBX64_RS17310	COG3813	Protein conserved in bacteria
DBX64_RS17330	COG0640	Transcriptional regulator
DBX64_RS17335	COG0538	isocitrate dehydrogenase activity
DBX64_RS17345	COG5001	Diguanylate cyclase
DBX64_RS17345	COG3300	MHYT domain
DBX64_RS17350	COG3706	GGDEF domain
DBX64_RS17435	COG0616	signal peptide processing
DBX64_RS17450	COG1802	Transcriptional regulator
DBX64_RS17450	COG4626	Terminase
DBX64_RS17495	COG3772	lysozyme
DBX64_RS17520	COG1403	HNH endonuclease
DBX64_RS17540	COG3344	reverse transcriptase
DBX64_RS17595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DBX64_RS17605	COG0582	viral genome integration into host DNA
DBX64_RS17610	COG0538	isocitrate dehydrogenase activity
DBX64_RS17615	COG1187	pseudouridine synthase activity
DBX64_RS17635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DBX64_RS17655	COG2205	protein histidine kinase activity
DBX64_RS17660	COG2850	peptidyl-arginine hydroxylation
DBX64_RS17665	COG1943	Transposase
DBX64_RS17685	COG1177	transmembrane transport
DBX64_RS17700	COG0318	PFAM AMP-dependent synthetase and ligase
DBX64_RS17705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DBX64_RS17710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DBX64_RS17715	COG0698	ribose 5-phosphate isomerase
DBX64_RS17730	COG3395	kinase activity
DBX64_RS17745	COG2390	Transcriptional regulator
DBX64_RS17755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DBX64_RS17765	COG4591	ABC-type transport system involved in lipoprotein release permease component
DBX64_RS17775	COG4591	ABC-type transport system involved in lipoprotein release permease component
DBX64_RS17785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DBX64_RS17790	COG1376	ErfK ybiS ycfS ynhG family protein
DBX64_RS17790	COG1388	LysM domain
DBX64_RS17805	COG1309	transcriptional regulator
DBX64_RS17820	COG3134	Outer membrane lipoprotein
DBX64_RS17825	COG1252	NADH dehydrogenase
DBX64_RS17850	COG5633	Lipoprotein
DBX64_RS17855	COG0537	adenosine 5'-monophosphoramidase activity
DBX64_RS17865	COG0084	hydrolase, TatD family'
DBX64_RS17870	COG0470	DNA polymerase III
DBX64_RS17880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DBX64_RS17885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DBX64_RS17890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DBX64_RS17905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DBX64_RS17925	COG1399	metal-binding, possibly nucleic acid-binding protein
DBX64_RS17945	COG1530	ribonuclease E activity
DBX64_RS17955	COG2814	Major facilitator Superfamily
DBX64_RS17975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBX64_RS18020	COG1560	Kdo2-lipid A biosynthetic process
DBX64_RS18035	COG5645	(Lipo)protein
DBX64_RS18070	COG3381	protein complex oligomerization
DBX64_RS18090	COG0583	DNA-binding transcription factor activity
DBX64_RS18100	COG1335	isochorismatase
DBX64_RS18110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DBX64_RS18115	COG1702	phosphate starvation-inducible protein PhoH
DBX64_RS18135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DBX64_RS18145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBX64_RS18160	COG1309	transcriptional regulator
DBX64_RS18195	COG2233	PERMEase
DBX64_RS18205	COG3729	General stress protein
DBX64_RS18235	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS18250	COG0531	amino acid
DBX64_RS18255	COG0174	glutamine synthetase
DBX64_RS18260	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DBX64_RS18265	COG1917	Cupin 2, conserved barrel domain protein
DBX64_RS18265	COG1396	sequence-specific DNA binding
DBX64_RS18270	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS18275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBX64_RS18280	COG0583	DNA-binding transcription factor activity
DBX64_RS18285	COG0473	3-isopropylmalate dehydrogenase activity
DBX64_RS18290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DBX64_RS18295	COG4638	Rieske (2fe-2S)
DBX64_RS18300	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS18305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBX64_RS18310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS18310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS18310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DBX64_RS18315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBX64_RS18320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBX64_RS18325	COG1882	Formate acetyltransferase
DBX64_RS18330	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DBX64_RS18335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBX64_RS18345	COG2207	Transcriptional regulator
DBX64_RS18350	COG3706	GGDEF domain
DBX64_RS18370	COG2200	EAL domain
DBX64_RS18380	COG0058	SHG alpha-glucan phosphorylase activity
DBX64_RS18395	COG0670	Belongs to the BI1 family
DBX64_RS18410	COG2207	Transcriptional regulator
DBX64_RS18415	COG1881	PFAM PEBP family protein
DBX64_RS18430	COG1832	CoA-binding protein
DBX64_RS18440	COG0210	DNA helicase
DBX64_RS18445	COG3304	Inner membrane component domain
DBX64_RS18450	COG1289	transmembrane transporter activity
DBX64_RS18455	COG3070	regulator of competence-specific genes
DBX64_RS18480	COG1067	ATP-dependent peptidase activity
DBX64_RS18490	COG3130	regulation of translation
DBX64_RS18495	COG3009	Protein conserved in bacteria
DBX64_RS18500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DBX64_RS18500	COG3008	intermembrane lipid transfer
DBX64_RS18505	COG2995	paraquat-inducible protein a
DBX64_RS18510	COG0488	(ABC) transporter
DBX64_RS18520	COG0633	Ferredoxin
DBX64_RS18520	COG3217	Mosc domain protein beta barrel domain protein
DBX64_RS18535	COG0431	NADPH-dependent FMN reductase
DBX64_RS18540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DBX64_RS18545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBX64_RS18550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DBX64_RS18560	COG0308	aminopeptidase N
DBX64_RS18570	COG1473	amidohydrolase
DBX64_RS18580	COG0814	amino acid
DBX64_RS18600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DBX64_RS18605	COG1448	Aminotransferase
DBX64_RS18610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBX64_RS18615	COG3108	Peptidase M15
DBX64_RS18620	COG2989	Protein conserved in bacteria
DBX64_RS18630	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
DBX64_RS18640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DBX64_RS18645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DBX64_RS18650	COG3173	Aminoglycoside phosphotransferase
DBX64_RS18665	COG3214	Protein conserved in bacteria
DBX64_RS18680	COG2333	competence protein COMEC
DBX64_RS18680	COG0658	competence protein
DBX64_RS18690	COG0539	negative regulation of cytoplasmic translation
DBX64_RS18710	COG2323	membrane
DBX64_RS18715	COG1944	ATP diphosphatase activity
DBX64_RS18720	COG2116	formate transmembrane transporter activity
DBX64_RS18725	COG1882	Formate acetyltransferase
DBX64_RS18730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DBX64_RS18735	COG0477	Major facilitator Superfamily
DBX64_RS18740	COG3302	dmso reductase anchor subunit
DBX64_RS18745	COG0437	4 iron, 4 sulfur cluster binding
DBX64_RS18750	COG0243	molybdopterin cofactor binding
DBX64_RS18760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DBX64_RS18770	COG1674	ftsk spoiiie
DBX64_RS18770	COG1178	ABC-type Fe3 transport system permease component
DBX64_RS18780	COG0492	ferredoxin-NADP+ reductase activity
DBX64_RS18785	COG4988	ABC transporter
DBX64_RS18790	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DBX64_RS18805	COG0542	response to heat
DBX64_RS18815	COG1278	Cold shock
DBX64_RS18825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX64_RS18830	COG3593	DNA synthesis involved in DNA repair
DBX64_RS18840	COG2431	L-lysine efflux transmembrane transporter activity
DBX64_RS18850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBX64_RS18860	COG0028	Belongs to the TPP enzyme family
DBX64_RS18865	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
DBX64_RS18870	COG0702	epimerase
DBX64_RS18875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBX64_RS18880	COG3023	N-Acetylmuramoyl-L-alanine amidase
DBX64_RS18885	COG4251	negative regulation of phosphorylation
DBX64_RS18885	COG3706	GGDEF domain
DBX64_RS18885	COG2203	Gaf domain
DBX64_RS18885	COG5001	Diguanylate cyclase
DBX64_RS18895	COG1126	abc transporter atp-binding protein
DBX64_RS18900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX64_RS18905	COG4215	(ABC) transporter
DBX64_RS18910	COG4160	amino acid transport
DBX64_RS18915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX64_RS18920	COG5002	protein histidine kinase activity
DBX64_RS18925	COG0745	RESPONSE REGULATOR receiver
DBX64_RS18940	COG1177	transmembrane transport
DBX64_RS18945	COG1176	ABC-type spermidine putrescine transport system, permease component I
DBX64_RS18950	COG3842	ATPase activity
DBX64_RS18955	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DBX64_RS18970	COG0778	Nitroreductase
DBX64_RS18995	COG3226	Transcriptional regulator
DBX64_RS19000	COG0738	Major facilitator superfamily
DBX64_RS19005	COG0561	phosphatase activity
DBX64_RS19010	COG2814	Major facilitator Superfamily
DBX64_RS19015	COG0671	phosphoesterase, PA-phosphatase related
DBX64_RS19020	COG1349	DNA-binding transcription factor activity
DBX64_RS19025	COG1686	Belongs to the peptidase S11 family
DBX64_RS19035	COG0625	glutathione transferase activity
DBX64_RS19040	COG2133	pyrroloquinoline quinone binding
DBX64_RS19050	COG2223	nitrite transmembrane transporter activity
DBX64_RS19070	COG0747	negative chemotaxis
DBX64_RS19085	COG0303	'Molybdopterin
DBX64_RS19090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DBX64_RS19095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DBX64_RS19100	COG1882	Formate acetyltransferase
DBX64_RS19105	COG0561	phosphatase activity
DBX64_RS19115	COG1609	Transcriptional regulator
DBX64_RS19120	COG2271	Major facilitator Superfamily
DBX64_RS19130	COG0488	(ABC) transporter
DBX64_RS19135	COG2365	Tyrosine phosphatase family
DBX64_RS19140	COG1376	ErfK ybiS ycfS ynhG family protein
DBX64_RS19145	COG2188	Transcriptional regulator
DBX64_RS19150	COG2723	6-phospho-beta-galactosidase activity
DBX64_RS19155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DBX64_RS19170	COG2194	sulfuric ester hydrolase activity
DBX64_RS19175	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DBX64_RS19190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX64_RS19195	COG0765	amino acid transport
DBX64_RS19200	COG1126	abc transporter atp-binding protein
DBX64_RS19205	COG0668	transmembrane transport
DBX64_RS19215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DBX64_RS19225	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DBX64_RS19235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DBX64_RS19240	COG1199	ATP-dependent helicase activity
DBX64_RS19245	COG0513	Belongs to the DEAD box helicase family
DBX64_RS19250	COG3958	Transketolase
DBX64_RS19265	COG2271	Major facilitator Superfamily
DBX64_RS19275	COG0583	DNA-binding transcription factor activity
DBX64_RS19280	COG1309	transcriptional regulator
DBX64_RS19285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX64_RS19290	COG1131	(ABC) transporter
DBX64_RS19295	COG0842	Transport permease protein
DBX64_RS19300	COG0842	Transport permease protein
DBX64_RS19310	COG3568	Endonuclease Exonuclease Phosphatase
DBX64_RS19315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBX64_RS19320	COG0392	lysyltransferase activity
DBX64_RS19325	COG0670	Belongs to the BI1 family
DBX64_RS19330	COG0314	molybdopterin synthase activity
DBX64_RS19335	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DBX64_RS19345	COG0521	Mo-molybdopterin cofactor biosynthetic process
DBX64_RS19365	COG0745	RESPONSE REGULATOR receiver
DBX64_RS19370	COG0642	Histidine kinase
DBX64_RS19395	COG2226	methyltransferase
DBX64_RS19410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DBX64_RS19415	COG1881	PFAM PEBP family protein
DBX64_RS19455	COG4677	pectinesterase activity
DBX64_RS19465	COG0589	response to stress
DBX64_RS19470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX64_RS19505	COG0789	Transcriptional regulator
DBX64_RS19510	COG2200	EAL domain
DBX64_RS19535	COG0561	phosphatase activity
DBX64_RS19540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DBX64_RS19545	COG4149	molybdate abc transporter
DBX64_RS19550	COG0725	ABC transporter, periplasmic molybdate-binding protein
DBX64_RS19560	COG2005	Transcriptional regulator
DBX64_RS19560	COG3585	molybdate ion transport
DBX64_RS19565	COG1119	ATPase activity
DBX64_RS19575	COG1085	galactose-1-phosphate uridylyltransferase
DBX64_RS19585	COG2017	converts alpha-aldose to the beta-anomer
DBX64_RS19595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DBX64_RS19610	COG3201	nicotinamide mononucleotide transporter
DBX64_RS19615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DBX64_RS19665	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DBX64_RS19670	COG2885	chlorophyll binding
DBX64_RS19680	COG3064	Membrane
DBX64_RS19685	COG0848	biopolymer transport protein
DBX64_RS19690	COG0811	peptide transport
DBX64_RS19695	COG0824	Thioesterase
DBX64_RS19700	COG3790	cyd operon protein YbgE
DBX64_RS19705	COG4890	Cyd operon protein YbgT
DBX64_RS19710	COG1294	oxidase, subunit
DBX64_RS19715	COG1271	oxidase subunit
DBX64_RS19720	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DBX64_RS19730	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBX64_RS19735	COG0567	Dehydrogenase, E1 component
DBX64_RS19740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DBX64_RS19745	COG1053	succinate dehydrogenase
DBX64_RS19750	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DBX64_RS19755	COG2009	succinate dehydrogenase
DBX64_RS19790	COG1984	allophanate hydrolase subunit 2
DBX64_RS19795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DBX64_RS19810	COG0415	Belongs to the DNA photolyase family
DBX64_RS19835	COG2205	protein histidine kinase activity
DBX64_RS19840	COG0745	RESPONSE REGULATOR receiver
DBX64_RS19850	COG0033	Phosphoglucomutase
DBX64_RS19860	COG0596	Alpha beta hydrolase
DBX64_RS19875	COG0735	belongs to the Fur family
DBX64_RS19915	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DBX64_RS19920	COG1940	carbohydrate kinase activity
DBX64_RS19920	COG1846	Transcriptional regulator
DBX64_RS19925	COG0647	UMP catabolic process
DBX64_RS19930	COG0367	asparagine synthase
DBX64_RS19970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DBX64_RS19980	COG1702	phosphate starvation-inducible protein PhoH
DBX64_RS20005	COG0765	amino acid transport
DBX64_RS20010	COG0765	amino acid transport
DBX64_RS20015	COG1126	abc transporter atp-binding protein
DBX64_RS20030	COG2888	peptidyl-tyrosine sulfation
DBX64_RS20045	COG1466	dna polymerase III delta subunit
DBX64_RS20060	COG0799	negative regulation of ribosome biogenesis
DBX64_RS20070	COG0768	penicillin binding
DBX64_RS20075	COG0772	Belongs to the SEDS family
DBX64_RS20080	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DBX64_RS20085	COG1686	Belongs to the peptidase S11 family
DBX64_RS20100	COG0583	DNA-binding transcription factor activity
DBX64_RS20110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DBX64_RS20115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DBX64_RS20135	COG3069	C4-dicarboxylate transmembrane transporter activity
DBX64_RS20140	COG3719	Belongs to the RNase T2 family
DBX64_RS20145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DBX64_RS20165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DBX64_RS20170	COG0583	DNA-binding transcription factor activity
DBX64_RS20175	COG3969	phosphoadenosine phosphosulfate
DBX64_RS20180	COG1475	DNA binding
DBX64_RS20185	COG0436	Aminotransferase
DBX64_RS20210	COG1129	ABC transporter
DBX64_RS20215	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS20220	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS20230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBX64_RS20245	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DBX64_RS20255	COG0402	S-adenosylhomocysteine deaminase activity
DBX64_RS20265	COG0483	inositol monophosphate 1-phosphatase activity
DBX64_RS20270	COG2271	Major facilitator Superfamily
DBX64_RS20300	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS20305	COG1129	ABC transporter
DBX64_RS20310	COG0371	Dehydrogenase
DBX64_RS20315	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS20330	COG2879	small protein
DBX64_RS20335	COG1966	Carbon starvation protein
DBX64_RS20345	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS20350	COG3433	isochorismatase activity
DBX64_RS20350	COG1535	isochorismatase
DBX64_RS20355	COG1021	2,3-dihydroxybenzoate-AMP ligase
DBX64_RS20360	COG1169	isochorismate synthase
DBX64_RS20365	COG4592	Periplasmic binding protein
DBX64_RS20375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX64_RS20380	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX64_RS20385	COG1120	ATPase activity
DBX64_RS20390	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DBX64_RS20390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBX64_RS20395	COG3251	PFAM MbtH domain protein
DBX64_RS20400	COG2382	esterase
DBX64_RS20405	COG4771	TonB-dependent receptor
DBX64_RS20410	COG2977	Belongs to the P-Pant transferase superfamily
DBX64_RS20415	COG3958	Transketolase
DBX64_RS20420	COG3959	Transketolase, thiamine diphosphate binding domain
DBX64_RS20425	COG2390	Transcriptional regulator
DBX64_RS20430	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DBX64_RS20435	COG1879	ABC-type sugar transport system periplasmic component
DBX64_RS20445	COG1129	ABC transporter
DBX64_RS20450	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS20460	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS20470	COG0583	DNA-binding transcription factor activity
DBX64_RS20475	COG0668	transmembrane transport
DBX64_RS20485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DBX64_RS20510	COG0747	negative chemotaxis
DBX64_RS20515	COG0601	transmembrane transport
DBX64_RS20520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX64_RS20525	COG0444	Belongs to the ABC transporter superfamily
DBX64_RS20530	COG4608	Belongs to the ABC transporter superfamily
DBX64_RS20540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DBX64_RS20545	COG4221	oxidoreductase activity
DBX64_RS20555	COG4215	(ABC) transporter
DBX64_RS20560	COG0765	amino acid transport
DBX64_RS20565	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DBX64_RS20580	COG0697	spore germination
DBX64_RS20595	COG4608	Belongs to the ABC transporter superfamily
DBX64_RS20600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX64_RS20620	COG3698	Phosphodiester glycosidase
DBX64_RS20660	COG2315	Protein conserved in bacteria
DBX64_RS20665	COG0778	Nitroreductase
DBX64_RS20675	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX64_RS20685	COG3716	PTS system mannose fructose sorbose family IID component
DBX64_RS20690	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DBX64_RS20695	COG2222	sugar isomerase
DBX64_RS20700	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DBX64_RS20700	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DBX64_RS20715	COG0477	Major facilitator Superfamily
DBX64_RS20720	COG0668	transmembrane transport
DBX64_RS20725	COG1609	Transcriptional regulator
DBX64_RS20735	COG0673	inositol 2-dehydrogenase activity
DBX64_RS20745	COG2211	Major facilitator Superfamily
DBX64_RS20750	COG1113	amino acid transport
DBX64_RS20765	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS20770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBX64_RS20780	COG0531	amino acid
DBX64_RS20825	COG0667	Aldo Keto reductase
DBX64_RS20830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX64_RS20835	COG1473	amidohydrolase
DBX64_RS20865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX64_RS20870	COG1120	ATPase activity
DBX64_RS20875	COG1566	PFAM secretion protein HlyD family protein
DBX64_RS20920	COG4211	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS20925	COG1129	ABC transporter
DBX64_RS20940	COG0673	inositol 2-dehydrogenase activity
DBX64_RS20970	COG3104	oligopeptide transport
DBX64_RS20975	COG1982	Orn Lys Arg decarboxylase major
DBX64_RS20980	COG0531	amino acid
DBX64_RS20985	COG3710	Transcriptional regulator
DBX64_RS20995	COG1560	Kdo2-lipid A biosynthetic process
DBX64_RS21010	COG3188	usher protein
DBX64_RS21015	COG3121	Chaperone
DBX64_RS21020	COG3539	Fimbrial protein
DBX64_RS21070	COG2501	S4 domain
DBX64_RS21075	COG1988	membrane-bound metal-dependent
DBX64_RS21095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DBX64_RS21110	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DBX64_RS21115	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DBX64_RS21120	COG0549	Belongs to the carbamate kinase family
DBX64_RS21130	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DBX64_RS21135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DBX64_RS21140	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DBX64_RS21145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DBX64_RS21150	COG3257	ureidoglycine aminohydrolase activity
DBX64_RS21155	COG1929	Belongs to the glycerate kinase type-1 family
DBX64_RS21160	COG2233	PERMEase
DBX64_RS21170	COG1953	Uracil, thiamine, allantoin
DBX64_RS21185	COG2084	Dehydrogenase
DBX64_RS21190	COG3622	Belongs to the hyi family
DBX64_RS21195	COG3960	tartronate-semialdehyde synthase activity
DBX64_RS21230	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DBX64_RS21235	COG4181	ATPase activity
DBX64_RS21240	COG2755	lipolytic protein G-D-S-L family
DBX64_RS21245	COG0300	oxidoreductase activity
DBX64_RS21250	COG3118	belongs to the thioredoxin family
DBX64_RS21255	COG0390	transport system, permease component
DBX64_RS21260	COG4619	ABC transporter
DBX64_RS21265	COG0330	HflC and HflK could
DBX64_RS21270	COG1585	Membrane protein implicated in regulation of membrane protease activity
DBX64_RS21285	COG3735	TraB family
DBX64_RS21290	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DBX64_RS21300	COG2223	nitrite transmembrane transporter activity
DBX64_RS21305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DBX64_RS21305	COG4651	solute:proton antiporter activity
DBX64_RS21310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX64_RS21350	COG2832	Protein of unknown function (DUF454)
DBX64_RS21355	COG3923	Primosomal replication protein n
DBX64_RS21370	COG3264	Mechanosensitive ion channel
DBX64_RS21370	COG1196	nuclear chromosome segregation
DBX64_RS21375	COG1309	transcriptional regulator
DBX64_RS21380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX64_RS21385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DBX64_RS21400	COG0110	maltose O-acetyltransferase activity
DBX64_RS21450	COG1874	Beta-galactosidase
DBX64_RS21455	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DBX64_RS21460	COG3833	ABC-type maltose transport systems, permease component
DBX64_RS21465	COG1175	transmembrane transport
DBX64_RS21470	COG2182	Extracellular solute-binding protein
DBX64_RS21480	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DBX64_RS21495	COG2364	Membrane
DBX64_RS21525	COG3695	enzyme binding
DBX64_RS21530	COG3126	Type III secretion system lipoprotein chaperone (YscW)
DBX64_RS21535	COG1946	Acyl-CoA thioesterase
DBX64_RS21540	COG0004	ammonium transporteR
DBX64_RS21545	COG0347	Belongs to the P(II) protein family
DBX64_RS21550	COG1132	(ABC) transporter
DBX64_RS21555	COG1132	(ABC) transporter
DBX64_RS21560	COG1522	sequence-specific DNA binding
DBX64_RS21575	COG4533	DNA binding
DBX64_RS21585	COG0824	Thioesterase
DBX64_RS21590	COG1555	photosystem II stabilization
DBX64_RS21595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBX64_RS21600	COG0776	regulation of translation
DBX64_RS21605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DBX64_RS21625	COG0271	Belongs to the BolA IbaG family
DBX64_RS21630	COG3056	Lipoprotein
DBX64_RS21635	COG2223	nitrite transmembrane transporter activity
DBX64_RS21640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DBX64_RS21645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DBX64_RS21650	COG1845	cytochrome c oxidase, subunit III
DBX64_RS21655	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DBX64_RS21670	COG1414	Transcriptional regulator
DBX64_RS21675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DBX64_RS21680	COG1053	succinate dehydrogenase
DBX64_RS21690	COG1053	succinate dehydrogenase
DBX64_RS21705	COG0673	inositol 2-dehydrogenase activity
DBX64_RS21710	COG2814	Major facilitator Superfamily
DBX64_RS21720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DBX64_RS21725	COG0693	protein deglycase activity
DBX64_RS21745	COG0142	geranyltranstransferase activity
DBX64_RS21755	COG0667	Aldo Keto reductase
DBX64_RS21760	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DBX64_RS21780	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DBX64_RS21780	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DBX64_RS21790	COG4238	major outer membrane lipoprotein
DBX64_RS21810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DBX64_RS21815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DBX64_RS21820	COG1862	Preprotein translocase
DBX64_RS21845	COG0450	alkyl hydroperoxide reductase
DBX64_RS21855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS21870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX64_RS21880	COG1228	amidohydrolase
DBX64_RS21890	COG1335	isochorismatase
DBX64_RS21895	COG0583	DNA-binding transcription factor activity
DBX64_RS21900	COG0366	Alpha amylase catalytic
DBX64_RS21925	COG0420	3'-5' exonuclease activity
DBX64_RS21930	COG0419	ATPase involved in DNA repair
DBX64_RS21935	COG1940	carbohydrate kinase activity
DBX64_RS21950	COG4126	flavin adenine dinucleotide binding
DBX64_RS21960	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DBX64_RS21965	COG3416	Protein conserved in bacteria
DBX64_RS21975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DBX64_RS21985	COG1785	Belongs to the alkaline phosphatase family
DBX64_RS22025	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
DBX64_RS22030	COG1335	isochorismatase
DBX64_RS22035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DBX64_RS22040	COG0113	porphobilinogen synthase activity
DBX64_RS22050	COG2175	clavaminate synthase activity
DBX64_RS22055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DBX64_RS22060	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DBX64_RS22065	COG4521	taurine ABC transporter
DBX64_RS22070	COG2040	homocysteine
DBX64_RS22075	COG0833	amino acid
DBX64_RS22100	COG4303	Ethanolamine ammonia lyase large subunit
DBX64_RS22105	COG4302	ethanolamine ammonia-lyase activity
DBX64_RS22145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX64_RS22150	COG1126	abc transporter atp-binding protein
DBX64_RS22155	COG4597	amino acid ABC transporter
DBX64_RS22160	COG0765	amino acid transport
DBX64_RS22175	COG3188	usher protein
DBX64_RS22200	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DBX64_RS22210	COG3639	organic phosphonate transmembrane transporter activity
DBX64_RS22230	COG0791	NLP P60 protein
DBX64_RS22280	COG2909	trisaccharide binding
DBX64_RS22285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DBX64_RS22290	COG0022	dehydrogenase e1 component
DBX64_RS22295	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBX64_RS22300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBX64_RS22320	COG1070	Carbohydrate kinase
DBX64_RS22325	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS22330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBX64_RS22335	COG3775	system Galactitol-specific IIC component
DBX64_RS22340	COG0625	glutathione transferase activity
DBX64_RS22345	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DBX64_RS22360	COG0579	oxidoreductase
DBX64_RS22365	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS22370	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DBX64_RS22375	COG1113	amino acid transport
DBX64_RS22380	COG1802	Transcriptional regulator
DBX64_RS22400	COG2195	Cleaves the N-terminal amino acid of tripeptides
DBX64_RS22405	COG0454	-acetyltransferase
DBX64_RS22420	COG2991	Protein conserved in bacteria
DBX64_RS22435	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DBX64_RS22440	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DBX64_RS22455	COG3034	peptidoglycan biosynthetic process
DBX64_RS22460	COG0121	glutamine amidotransferase
DBX64_RS22470	COG1960	acyl-CoA dehydrogenase activity
DBX64_RS22475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DBX64_RS22485	COG0583	DNA-binding transcription factor activity
DBX64_RS22495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DBX64_RS22505	COG2226	methyltransferase
DBX64_RS22515	COG1388	LysM domain
DBX64_RS22515	COG0741	lytic transglycosylase activity
DBX64_RS22520	COG2226	methyltransferase
DBX64_RS22530	COG2814	Major facilitator Superfamily
DBX64_RS22535	COG0583	DNA-binding transcription factor activity
DBX64_RS22540	COG0656	L-ascorbic acid biosynthetic process
DBX64_RS22575	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DBX64_RS22585	COG2011	ABC-type metal ion transport system permease component
DBX64_RS22590	COG1464	Belongs to the NlpA lipoprotein family
DBX64_RS22600	COG1720	tRNA m6t6A37 methyltransferase activity
DBX64_RS22610	COG0791	NLP P60 protein
DBX64_RS22615	COG3015	lipoprotein NlpE involved in copper resistance
DBX64_RS22620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DBX64_RS22635	COG4568	rho-dependent transcription termination
DBX64_RS22645	COG0346	lactoylglutathione lyase activity
DBX64_RS22650	COG1982	Orn Lys Arg decarboxylase major
DBX64_RS22660	COG0587	DNA-directed DNA polymerase activity
DBX64_RS22690	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
DBX64_RS22700	COG0750	zinc metalloprotease
DBX64_RS22705	COG0575	Belongs to the CDS family
DBX64_RS22715	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DBX64_RS22740	COG0024	Methionine aminopeptidase
DBX64_RS22745	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DBX64_RS22760	COG3835	regulator
DBX64_RS22765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DBX64_RS22785	COG2860	membrane
DBX64_RS22805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX64_RS22810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DBX64_RS22815	COG1120	ATPase activity
DBX64_RS22820	COG4774	siderophore transport
DBX64_RS22825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DBX64_RS22925	COG1643	Atp-dependent helicase
DBX64_RS22930	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DBX64_RS22950	COG0617	tRNA 3'-terminal CCA addition
DBX64_RS22955	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DBX64_RS22975	COG0726	polysaccharide deacetylase
DBX64_RS22980	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS22985	COG0842	Transport permease protein
DBX64_RS22990	COG1131	(ABC) transporter
DBX64_RS22995	COG0288	reversible hydration of carbon dioxide
DBX64_RS23010	COG4993	Dehydrogenase
DBX64_RS23015	COG2132	Multicopper oxidase
DBX64_RS23060	COG3064	Membrane
DBX64_RS23075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBX64_RS23080	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBX64_RS23085	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DBX64_RS23090	COG2186	Transcriptional regulator
DBX64_RS23095	COG1113	amino acid transport
DBX64_RS23100	COG2211	Major facilitator Superfamily
DBX64_RS23105	COG3940	Belongs to the glycosyl hydrolase 43 family
DBX64_RS23110	COG3725	Membrane protein required for beta-lactamase induction
DBX64_RS23115	COG3023	N-Acetylmuramoyl-L-alanine amidase
DBX64_RS23125	COG4969	Belongs to the N-Me-Phe pilin family
DBX64_RS23130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DBX64_RS23135	COG1459	type II secretion system
DBX64_RS23160	COG0494	nUDIX hydrolase
DBX64_RS23180	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DBX64_RS23185	COG0849	cell division
DBX64_RS23210	COG0772	Belongs to the SEDS family
DBX64_RS23225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DBX64_RS23230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DBX64_RS23235	COG0768	penicillin binding
DBX64_RS23255	COG1609	Transcriptional regulator
DBX64_RS23265	COG0028	Belongs to the TPP enzyme family
DBX64_RS23310	COG0738	Major facilitator superfamily
DBX64_RS23320	COG0583	DNA-binding transcription factor activity
DBX64_RS23325	COG2271	Major facilitator Superfamily
DBX64_RS23330	COG2814	Major facilitator Superfamily
DBX64_RS23350	COG1178	ABC-type Fe3 transport system permease component
DBX64_RS23360	COG0586	Pfam SNARE associated Golgi protein
DBX64_RS23380	COG0235	Class ii aldolase
DBX64_RS23385	COG0417	DNA replication proofreading
DBX64_RS23395	COG0564	pseudouridine synthase activity
DBX64_RS23405	COG3493	citrate carrier protein
DBX64_RS23420	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DBX64_RS23425	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DBX64_RS23435	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DBX64_RS23480	COG0505	Belongs to the CarA family
DBX64_RS23490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DBX64_RS23515	COG1047	Peptidyl-prolyl cis-trans
DBX64_RS23530	COG0196	riboflavin kinase activity
DBX64_RS23540	COG0583	DNA-binding transcription factor activity
DBX64_RS23565	COG4735	regulation of single-species biofilm formation
DBX64_RS23570	COG1584	GPR1 FUN34 yaaH family protein
DBX64_RS23575	COG0477	Major facilitator Superfamily
DBX64_RS23580	COG0521	Mo-molybdopterin cofactor biosynthetic process
DBX64_RS23585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DBX64_RS23590	COG1115	amino acid carrier protein
DBX64_RS23605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DBX64_RS23615	COG0527	aspartate kinase activity
DBX64_RS23615	COG0460	homoserine dehydrogenase
DBX64_RS23625	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DBX64_RS23635	COG0745	RESPONSE REGULATOR receiver
DBX64_RS23640	COG4452	Inner membrane protein CreD
DBX64_RS23645	COG2205	protein histidine kinase activity
DBX64_RS23650	COG0745	RESPONSE REGULATOR receiver
DBX64_RS23655	COG3045	CreA protein
DBX64_RS23660	COG3708	Transcriptional regulator
DBX64_RS23660	COG2207	Transcriptional regulator
DBX64_RS23680	COG0741	lytic transglycosylase activity
DBX64_RS23685	COG0488	(ABC) transporter
DBX64_RS23695	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DBX64_RS23700	COG0560	Phosphoserine phosphatase
DBX64_RS23705	COG3726	membrane protein affecting hemolysin expression
DBX64_RS23735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DBX64_RS23740	COG0084	hydrolase, TatD family'
DBX64_RS23745	COG4667	esterase of the alpha-beta hydrolase superfamily
DBX64_RS23755	COG2823	Periplasmic or secreted lipoprotein
DBX64_RS23765	COG1011	Hydrolase
DBX64_RS23770	COG0456	acetyltransferase
DBX64_RS23775	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
DBX64_RS23810	COG3706	GGDEF domain
DBX64_RS23815	COG4114	ferric iron reductase
DBX64_RS23820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBX64_RS23820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBX64_RS23825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DBX64_RS23830	COG2197	response regulator
DBX64_RS23835	COG2197	response regulator
DBX64_RS23850	COG2966	Psort location CytoplasmicMembrane, score
DBX64_RS23865	COG1484	DNA-dependent DNA replication
DBX64_RS23880	COG5464	transposase or invertase
DBX64_RS23890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DBX64_RS23895	COG3716	PTS system mannose fructose sorbose family IID component
DBX64_RS23900	COG3715	PTS system
DBX64_RS23915	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DBX64_RS23915	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DBX64_RS23920	COG0456	acetyltransferase
DBX64_RS23920	COG1214	PFAM Peptidase M22, glycoprotease
DBX64_RS23930	COG1737	Transcriptional regulator
DBX64_RS23935	COG0800	Aldolase
DBX64_RS23940	COG3734	2-keto-3-deoxy-galactonokinase
DBX64_RS23955	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DBX64_RS23985	COG1846	Transcriptional regulator
DBX64_RS23995	COG0179	Fumarylacetoacetate (FAA) hydrolase
DBX64_RS24005	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS24010	COG3384	dioxygenase
DBX64_RS24020	COG3971	2-oxopent-4-enoate hydratase activity
DBX64_RS24040	COG2368	4-hydroxyphenylacetate
DBX64_RS24045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DBX64_RS24060	COG1966	Carbon starvation protein
DBX64_RS24065	COG2879	small protein
DBX64_RS24070	COG0523	cobalamin synthesis protein
DBX64_RS24080	COG1012	belongs to the aldehyde dehydrogenase family
DBX64_RS24085	COG5464	transposase or invertase
DBX64_RS24090	COG2207	Transcriptional regulator
DBX64_RS24090	COG1917	Cupin 2, conserved barrel domain protein
DBX64_RS24100	COG2733	membrane
DBX64_RS24115	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DBX64_RS24120	COG1924	4 iron, 4 sulfur cluster binding
DBX64_RS24135	COG1566	PFAM secretion protein HlyD family protein
DBX64_RS24145	COG5457	Domain of unknown function (DUF1127)
DBX64_RS24150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBX64_RS24160	COG0583	DNA-binding transcription factor activity
DBX64_RS24165	COG2249	NAD(P)H dehydrogenase (quinone) activity
DBX64_RS24175	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS24180	COG1129	ABC transporter
DBX64_RS24185	COG1879	ABC-type sugar transport system periplasmic component
DBX64_RS24195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX64_RS24205	COG0842	Transport permease protein
DBX64_RS24235	COG2850	peptidyl-arginine hydroxylation
DBX64_RS24250	COG5002	protein histidine kinase activity
DBX64_RS24255	COG0745	RESPONSE REGULATOR receiver
DBX64_RS24260	COG1538	Outer membrane efflux protein
DBX64_RS24265	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX64_RS24270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX64_RS24275	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DBX64_RS24285	COG3040	lipid binding
DBX64_RS24290	COG0789	Transcriptional regulator
DBX64_RS24295	COG3631	Ketosteroid isomerase-related protein
DBX64_RS24300	COG0300	oxidoreductase activity
DBX64_RS24315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DBX64_RS24335	COG3272	Protein of unknown function (DUF1722)
DBX64_RS24340	COG4580	involved in the transport of maltose and maltodextrins
DBX64_RS24345	COG2115	Belongs to the xylose isomerase family
DBX64_RS24350	COG2211	Major facilitator Superfamily
DBX64_RS24355	COG3507	Belongs to the glycosyl hydrolase 43 family
DBX64_RS24375	COG1216	Glycosyl transferase, family 2
DBX64_RS24485	COG0071	Belongs to the small heat shock protein (HSP20) family
DBX64_RS24535	COG0582	viral genome integration into host DNA
DBX64_RS24545	COG0288	reversible hydration of carbon dioxide
DBX64_RS24550	COG0659	secondary active sulfate transmembrane transporter activity
DBX64_RS24555	COG1064	alcohol dehydrogenase
DBX64_RS24560	COG1175	transmembrane transport
DBX64_RS24565	COG0395	ABC-type sugar transport system, permease component
DBX64_RS24570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DBX64_RS24575	COG3842	ATPase activity
DBX64_RS24590	COG1082	Xylose isomerase domain protein TIM barrel
DBX64_RS24600	COG3962	Belongs to the TPP enzyme family
DBX64_RS24605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBX64_RS24610	COG0837	glucose binding
DBX64_RS24610	COG1737	Transcriptional regulator
DBX64_RS24615	COG3718	enzyme involved in inositol metabolism
DBX64_RS24630	COG0433	COG0433 Predicted ATPase
DBX64_RS24635	COG0795	lipopolysaccharide-transporting ATPase activity
DBX64_RS24640	COG0795	lipopolysaccharide-transporting ATPase activity
DBX64_RS24650	COG2927	DNA polymerase III (CHI subunit)
DBX64_RS24655	COG0525	valine-tRNA ligase activity
DBX64_RS24680	COG2731	YhcH YjgK YiaL family protein
DBX64_RS24715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBX64_RS24715	COG1263	PTS System
DBX64_RS24720	COG0366	Alpha amylase catalytic
DBX64_RS24725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBX64_RS24730	COG1486	melibiose metabolic process
DBX64_RS24755	COG0602	queuosine metabolic process
DBX64_RS24760	COG2026	Addiction module toxin, RelE StbE family
DBX64_RS24765	COG3077	Addiction module antitoxin, RelB DinJ family
DBX64_RS24770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBX64_RS24770	COG3711	transcriptional antiterminator
DBX64_RS24775	COG2706	6-phosphogluconolactonase activity
DBX64_RS24790	COG3964	amidohydrolase
DBX64_RS24830	COG0312	modulator of DNA gyrase
DBX64_RS24855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DBX64_RS24865	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS24870	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS24875	COG1129	ABC transporter
DBX64_RS24880	COG1879	ABC-type sugar transport system periplasmic component
DBX64_RS24895	COG2105	PFAM AIG2 family protein
DBX64_RS24900	COG2911	Protein conserved in bacteria
DBX64_RS24905	COG0729	surface antigen
DBX64_RS24915	COG1253	flavin adenine dinucleotide binding
DBX64_RS24930	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
DBX64_RS24945	COG1733	regulation of RNA biosynthetic process
DBX64_RS24950	COG0702	epimerase
DBX64_RS24960	COG0697	spore germination
DBX64_RS24970	COG1113	amino acid transport
DBX64_RS24975	COG0545	Peptidyl-prolyl cis-trans isomerase
DBX64_RS24980	COG3061	Opacity-associated protein A
DBX64_RS24990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DBX64_RS24995	COG2965	DNA replication, synthesis of RNA primer
DBX64_RS25055	COG1073	alpha beta
DBX64_RS25060	COG3650	response to hydrogen peroxide
DBX64_RS25070	COG1960	acyl-CoA dehydrogenase activity
DBX64_RS25075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBX64_RS25080	COG0557	exoribonuclease II activity
DBX64_RS25095	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
DBX64_RS25105	COG0330	HflC and HflK could
DBX64_RS25110	COG0330	HflC and HflK could
DBX64_RS25115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DBX64_RS25135	COG0860	N-Acetylmuramoyl-L-alanine amidase
DBX64_RS25140	COG0802	atpase or kinase
DBX64_RS25145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DBX64_RS25145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DBX64_RS25150	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DBX64_RS25170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBX64_RS25190	COG3264	Mechanosensitive ion channel
DBX64_RS25190	COG1511	domain protein
DBX64_RS25205	COG1053	succinate dehydrogenase
DBX64_RS25210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DBX64_RS25230	COG2076	Multidrug Resistance protein
DBX64_RS25235	COG5510	response to toxic substance
DBX64_RS25250	COG1509	lysine 2,3-aminomutase activity
DBX64_RS25315	COG0531	amino acid
DBX64_RS25320	COG3030	protein affecting phage T7 exclusion by the F plasmid
DBX64_RS25325	COG1027	Aspartate ammonia-lyase
DBX64_RS25330	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DBX64_RS25345	COG1309	transcriptional regulator
DBX64_RS25375	COG0457	Tetratricopeptide repeat
DBX64_RS25380	COG1649	PFAM Uncharacterised BCR, COG1649
DBX64_RS25380	COG0726	polysaccharide deacetylase
DBX64_RS25385	COG1215	transferase activity, transferring glycosyl groups
DBX64_RS25400	COG0861	Integral membrane protein TerC family
DBX64_RS25440	COG1486	melibiose metabolic process
DBX64_RS25445	COG2169	Transcriptional regulator
DBX64_RS25455	COG2824	Alkylphosphonate utilization operon protein PhnA
DBX64_RS25460	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DBX64_RS25465	COG2188	Transcriptional regulator
DBX64_RS25470	COG3624	Phosphonate C-P lyase system protein PhnG
DBX64_RS25475	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
DBX64_RS25480	COG3626	phosphonate metabolism
DBX64_RS25485	COG3627	carbon phosphorus lyase activity
DBX64_RS25490	COG4107	phosphonate C-P lyase system protein PhnK
DBX64_RS25495	COG4778	phosphonate C-P lyase system protein PhnL
DBX64_RS25500	COG3454	Phosphonate metabolism
DBX64_RS25510	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DBX64_RS25520	COG0784	Response regulator, receiver
DBX64_RS25520	COG4191	Histidine kinase
DBX64_RS25525	COG1129	ABC transporter
DBX64_RS25530	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBX64_RS25555	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
DBX64_RS25560	COG1301	dicarboxylic acid transport
DBX64_RS25570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DBX64_RS25575	COG3162	membrane
DBX64_RS25605	COG3539	Fimbrial protein
DBX64_RS25610	COG1346	cytolysis
DBX64_RS25615	COG1380	Effector of murein hydrolase LrgA
DBX64_RS25620	COG0583	DNA-binding transcription factor activity
DBX64_RS25625	COG0025	NhaP-type Na H and K H
DBX64_RS25630	COG2252	PERMEase
DBX64_RS25635	COG0625	glutathione transferase activity
DBX64_RS25640	COG0789	Transcriptional regulator
DBX64_RS25650	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DBX64_RS25680	COG1234	tRNA 3'-trailer cleavage
DBX64_RS25685	COG1609	Transcriptional regulator
DBX64_RS25690	COG0483	inositol monophosphate 1-phosphatase activity
DBX64_RS25700	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DBX64_RS25720	COG4771	TonB-dependent receptor
DBX64_RS25725	COG0741	lytic transglycosylase activity
DBX64_RS25740	COG2315	Protein conserved in bacteria
DBX64_RS25745	COG0432	Pfam Uncharacterised protein family UPF0047
DBX64_RS25760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DBX64_RS25765	COG0305	Participates in initiation and elongation during chromosome replication
DBX64_RS25780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DBX64_RS25790	COG0735	belongs to the Fur family
DBX64_RS25795	COG3237	CsbD-like
DBX64_RS25805	COG0534	Mate efflux family protein
DBX64_RS25815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DBX64_RS25885	COG0251	oxidation-reduction process
DBX64_RS25895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DBX64_RS25905	COG0527	aspartate kinase activity
DBX64_RS25955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DBX64_RS25965	COG0456	acetyltransferase
DBX64_RS25995	COG0151	Belongs to the GarS family
DBX64_RS26005	COG4191	Histidine kinase
DBX64_RS26010	COG3678	ATP-independent chaperone mediated protein folding
DBX64_RS26045	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
DBX64_RS26060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DBX64_RS26065	COG2104	thiamine diphosphate biosynthetic process
DBX64_RS26080	COG3706	GGDEF domain
DBX64_RS26090	COG1447	Phosphotransferase system cellobiose-specific component IIA
DBX64_RS26095	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DBX64_RS26130	COG0250	Participates in transcription elongation, termination and antitermination
DBX64_RS26185	COG3039	Transposase
DBX64_RS26225	COG3039	Transposase
DBX64_RS26295	COG2916	Histone family protein nucleoid-structuring protein H-NS
DBX64_RS26310	COG2801	Transposase and inactivated derivatives
DBX64_RS26320	COG2026	Addiction module toxin, RelE StbE family
DBX64_RS26335	COG0025	NhaP-type Na H and K H
DBX64_RS26370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DBX64_RS26380	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DBX64_RS26745	COG0633	Ferredoxin
DBX64_RS27070	COG0210	DNA helicase
DBX64_RS27340	COG0789	Transcriptional regulator
DBX64_RS27370	COG1358	cellular component organization or biogenesis
DBX64_RS27440	COG3039	Transposase
DBX64_RS27525	COG3344	reverse transcriptase
DBX64_RS27560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBX64_RS27585	COG2144	transferase activity, transferring acyl groups
DBX64_RS27620	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
DBX64_RS27640	COG4245	von Willebrand factor, type A
DBX64_RS27645	COG4245	von Willebrand factor, type A
DBX64_RS27655	COG4245	von Willebrand factor, type A
DBX64_RS27675	COG1358	cellular component organization or biogenesis
DBX64_RS27765	COG3321	synthase
DBX64_RS27765	COG1028	Short-chain dehydrogenase reductase Sdr
DBX64_RS27765	COG0604	alcohol dehydrogenase
DBX64_RS27780	COG1522	sequence-specific DNA binding
DBX64_RS27950	COG0523	cobalamin synthesis protein
DBX64_RS27970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX64_RS27980	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DBX64_RS28015	COG0500	methyltransferase
DBX64_RS28050	COG2382	esterase
DBX64_RS28070	COG1475	DNA binding
DBX64_RS28075	COG3969	phosphoadenosine phosphosulfate
DBX64_RS28090	COG1595	DNA-templated transcription, initiation
DBX64_RS28100	COG4772	TonB-dependent receptor
DBX64_RS28105	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DBX64_RS28120	COG5642	Protein of unknown function (DUF2384)
DBX64_RS28125	COG5654	RES domain protein
DBX64_RS28145	COG2916	Histone family protein nucleoid-structuring protein H-NS
DBX64_RS28150	COG0656	L-ascorbic acid biosynthetic process
DBX64_RS28175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBX64_RS28220	COG0735	belongs to the Fur family
DBX64_RS28225	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DBX64_RS28230	COG0523	cobalamin synthesis protein
DBX64_RS28305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DBX64_RS28390	COG4680	protein conserved in bacteria
DBX64_RS28395	COG5499	transcription regulator containing HTH domain
DBX64_RS28450	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DBX64_RS28465	COG0789	Transcriptional regulator
DBX64_RS28470	COG2205	protein histidine kinase activity
DBX64_RS28475	COG0745	RESPONSE REGULATOR receiver
DBX64_RS28480	COG1276	copper resistance
DBX64_RS28485	COG2372	response to copper ion
DBX64_RS28490	COG3667	copper resistance
DBX64_RS28495	COG2132	Multicopper oxidase
DBX64_RS28505	COG0739	heme binding
DBX64_RS28535	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBX64_RS28700	COG3436	PFAM IS66 Orf2 family protein
DBX64_RS28705	COG4372	Transposase
DBX64_RS28765	COG0768	penicillin binding
DBX64_RS28780	COG0697	spore germination
DBX64_RS28905	COG3173	Aminoglycoside phosphotransferase
DBX64_RS29090	COG1192	Involved in chromosome partitioning
DBX64_RS29110	COG3344	reverse transcriptase
DBX64_RS29205	COG1475	DNA binding
DBX64_RS29275	COG5499	transcription regulator containing HTH domain
DBX64_RS29280	COG3328	transposase activity
DBX64_RS29560	COG1120	ATPase activity
DBX64_RS29565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBX64_RS29880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DBX64_RS30040	COG3093	addiction module antidote protein HigA
DBX64_RS30055	COG0629	single-stranded DNA binding
DBX64_RS30065	COG4962	Type ii secretion system protein e
DBX64_RS30075	COG5268	conjugation
DBX64_RS30080	COG3451	type IV secretory pathway VirB4
DBX64_RS30115	COG3846	protein secretion by the type IV secretion system
DBX64_RS30170	COG0489	protein tyrosine kinase activity
DBX64_RS30185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DBX64_RS30195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DBX64_RS30240	COG3504	Conjugal transfer protein