locus-tag	class	description
FLM25_RS00005	COG2723	6-phospho-beta-galactosidase activity
FLM25_RS00015	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FLM25_RS00025	COG3260	NADH ubiquinone oxidoreductase 20
FLM25_RS00030	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FLM25_RS00035	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FLM25_RS00035	COG3261	NADH dehydrogenase
FLM25_RS00040	COG0650	Formate hydrogenlyase subunit 4
FLM25_RS00045	COG0651	ATP synthesis coupled electron transport
FLM25_RS00050	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FLM25_RS00065	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FLM25_RS00070	COG0298	carbon dioxide binding
FLM25_RS00075	COG0409	Hydrogenase expression formation protein
FLM25_RS00080	COG0309	Hydrogenase expression formation protein (HypE)
FLM25_RS00090	COG2723	6-phospho-beta-galactosidase activity
FLM25_RS00100	COG4580	involved in the transport of maltose and maltodextrins
FLM25_RS00105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLM25_RS00110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLM25_RS00115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLM25_RS00120	COG1447	Phosphotransferase system cellobiose-specific component IIA
FLM25_RS00125	COG1940	carbohydrate kinase activity
FLM25_RS00130	COG1609	Transcriptional regulator
FLM25_RS00135	COG0803	Belongs to the bacterial solute-binding protein 9 family
FLM25_RS00140	COG1121	(ABC) transporter
FLM25_RS00145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLM25_RS00150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLM25_RS00165	COG0679	Auxin Efflux Carrier
FLM25_RS00185	COG3720	iron ion transport
FLM25_RS00190	COG4558	Periplasmic binding protein
FLM25_RS00195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLM25_RS00235	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FLM25_RS00240	COG0163	prenyltransferase activity
FLM25_RS00265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLM25_RS00270	COG1388	LysM domain
FLM25_RS00270	COG4942	peptidase
FLM25_RS00330	COG2234	aminopeptidase activity
FLM25_RS00350	COG0720	synthase
FLM25_RS00355	COG0602	queuosine metabolic process
FLM25_RS00375	COG3956	TIGRFAM MazG family protein
FLM25_RS00380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLM25_RS00390	COG4999	Histidine kinase
FLM25_RS00390	COG3437	response regulator, receiver
FLM25_RS00390	COG2205	protein histidine kinase activity
FLM25_RS00390	COG3850	Histidine kinase
FLM25_RS00395	COG1929	Belongs to the glycerate kinase type-1 family
FLM25_RS00400	COG4948	Mandelate Racemase Muconate Lactonizing
FLM25_RS00405	COG4948	Mandelate Racemase Muconate Lactonizing
FLM25_RS00410	COG2271	Major facilitator Superfamily
FLM25_RS00415	COG0716	FMN binding
FLM25_RS00420	COG0564	pseudouridine synthase activity
FLM25_RS00425	COG3098	single-species biofilm formation
FLM25_RS00440	COG1611	Belongs to the LOG family
FLM25_RS00445	COG0814	amino acid
FLM25_RS00450	COG1760	l-serine dehydratase
FLM25_RS00455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLM25_RS00465	COG0477	Major facilitator Superfamily
FLM25_RS00470	COG1464	Belongs to the NlpA lipoprotein family
FLM25_RS00475	COG2011	ABC-type metal ion transport system permease component
FLM25_RS00480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FLM25_RS00495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLM25_RS00515	COG1454	alcohol dehydrogenase
FLM25_RS00520	COG0235	Class ii aldolase
FLM25_RS00525	COG0738	Major facilitator superfamily
FLM25_RS00545	COG1349	DNA-binding transcription factor activity
FLM25_RS00555	COG2363	Small membrane protein
FLM25_RS00560	COG0583	DNA-binding transcription factor activity
FLM25_RS00570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FLM25_RS00575	COG2166	iron-sulfur cluster assembly
FLM25_RS00580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FLM25_RS00585	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FLM25_RS00780	COG1454	alcohol dehydrogenase
FLM25_RS00780	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS00785	COG4656	Part of a membrane complex involved in electron transport
FLM25_RS00815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FLM25_RS00820	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLM25_RS00825	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FLM25_RS00825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FLM25_RS00835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FLM25_RS00840	COG1074	ATP-dependent DNA helicase activity
FLM25_RS00845	COG1025	Belongs to the peptidase M16 family
FLM25_RS00850	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FLM25_RS00855	COG4967	type IV pilus modification protein PilV
FLM25_RS00865	COG4795	General secretion pathway protein
FLM25_RS00870	COG2165	general secretion pathway protein
FLM25_RS00905	COG0861	Integral membrane protein TerC family
FLM25_RS00915	COG0667	Aldo Keto reductase
FLM25_RS00930	COG1609	Transcriptional regulator
FLM25_RS00940	COG2186	Transcriptional regulator
FLM25_RS00945	COG2723	6-phospho-beta-galactosidase activity
FLM25_RS00950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLM25_RS00955	COG1609	Transcriptional regulator
FLM25_RS00965	COG0583	DNA-binding transcription factor activity
FLM25_RS00970	COG1794	racemase activity, acting on amino acids and derivatives
FLM25_RS00975	COG1917	Cupin 2, conserved barrel domain protein
FLM25_RS00990	COG1175	transmembrane transport
FLM25_RS00995	COG0395	ABC-type sugar transport system, permease component
FLM25_RS01000	COG3842	ATPase activity
FLM25_RS01035	COG2814	Major facilitator Superfamily
FLM25_RS01040	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS01045	COG0823	Involved in the tonB-independent uptake of proteins
FLM25_RS01055	COG0183	Belongs to the thiolase family
FLM25_RS01070	COG0814	amino acid
FLM25_RS01075	COG0667	Aldo Keto reductase
FLM25_RS01125	COG0697	spore germination
FLM25_RS01130	COG1846	Transcriptional regulator
FLM25_RS01135	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FLM25_RS01140	COG0582	viral genome integration into host DNA
FLM25_RS01145	COG4974	Belongs to the 'phage' integrase family
FLM25_RS01155	COG3539	Fimbrial protein
FLM25_RS01160	COG3121	Chaperone
FLM25_RS01165	COG3188	usher protein
FLM25_RS01170	COG3539	Fimbrial protein
FLM25_RS01175	COG3539	Fimbrial protein
FLM25_RS01180	COG3539	Fimbrial protein
FLM25_RS01190	COG2388	GCN5-related N-acetyl-transferase
FLM25_RS01195	COG3592	Divergent 4Fe-4S mono-cluster
FLM25_RS01210	COG1289	transmembrane transporter activity
FLM25_RS01215	COG1538	Outer membrane efflux protein
FLM25_RS01225	COG3104	oligopeptide transport
FLM25_RS01230	COG1393	Belongs to the ArsC family
FLM25_RS01235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FLM25_RS01270	COG0667	Aldo Keto reductase
FLM25_RS01285	COG2814	Major facilitator Superfamily
FLM25_RS01295	COG4942	peptidase
FLM25_RS01315	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FLM25_RS01325	COG4974	Belongs to the 'phage' integrase family
FLM25_RS01330	COG0716	FMN binding
FLM25_RS01340	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FLM25_RS01350	COG1272	protein, Hemolysin III
FLM25_RS01360	COG1737	Transcriptional regulator
FLM25_RS01365	COG2723	6-phospho-beta-galactosidase activity
FLM25_RS01385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLM25_RS01390	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS01410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLM25_RS01415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLM25_RS01420	COG0006	proline dipeptidase activity
FLM25_RS01440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FLM25_RS01445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLM25_RS01460	COG2968	Membrane
FLM25_RS01470	COG0668	transmembrane transport
FLM25_RS01475	COG0191	fructose-bisphosphate aldolase activity
FLM25_RS01490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FLM25_RS01495	COG0501	Belongs to the peptidase M48B family
FLM25_RS01515	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FLM25_RS01520	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS01550	COG1414	Transcriptional regulator
FLM25_RS01555	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS01570	COG2146	nitrite reductase [NAD(P)H] activity
FLM25_RS01605	COG2814	Major facilitator Superfamily
FLM25_RS01615	COG2356	endonuclease I
FLM25_RS01620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FLM25_RS01625	COG0189	ligase activity
FLM25_RS01645	COG2805	Type II/IV secretion system protein
FLM25_RS01650	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FLM25_RS01655	COG0762	integral membrane protein
FLM25_RS01670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FLM25_RS01680	COG3171	Protein conserved in bacteria
FLM25_RS01690	COG1194	a g-specific adenine glycosylase
FLM25_RS01705	COG2211	Major facilitator Superfamily
FLM25_RS01710	COG1982	Orn Lys Arg decarboxylase major
FLM25_RS01715	COG1811	Na channel or pump
FLM25_RS01725	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FLM25_RS01790	COG3423	Transcriptional regulator
FLM25_RS01795	COG1278	Cold shock
FLM25_RS01805	COG3423	Transcriptional regulator
FLM25_RS02060	COG0626	cystathionine gamma-synthase activity
FLM25_RS02065	COG0583	DNA-binding transcription factor activity
FLM25_RS02085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLM25_RS02090	COG0754	glutathionylspermidine amidase activity
FLM25_RS02105	COG0625	glutathione transferase activity
FLM25_RS02130	COG2211	Major facilitator Superfamily
FLM25_RS02135	COG0848	biopolymer transport protein
FLM25_RS02145	COG0626	cystathionine gamma-synthase activity
FLM25_RS02150	COG0586	Pfam SNARE associated Golgi protein
FLM25_RS02155	COG2207	Transcriptional regulator
FLM25_RS02160	COG1979	alcohol dehydrogenase
FLM25_RS02165	COG0656	L-ascorbic acid biosynthetic process
FLM25_RS02175	COG1032	radical SAM domain protein
FLM25_RS02180	COG2132	Multicopper oxidase
FLM25_RS02185	COG0204	Acyl-transferase
FLM25_RS02190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLM25_RS02195	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FLM25_RS02200	COG3111	PFAM Bacterial OB fold (BOF) protein
FLM25_RS02210	COG0642	Histidine kinase
FLM25_RS02215	COG2249	NAD(P)H dehydrogenase (quinone) activity
FLM25_RS02220	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FLM25_RS02230	COG3150	esterase
FLM25_RS02235	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FLM25_RS02240	COG3151	Protein conserved in bacteria
FLM25_RS02245	COG0494	nUDIX hydrolase
FLM25_RS02260	COG0754	glutathionylspermidine amidase activity
FLM25_RS02265	COG3384	dioxygenase
FLM25_RS02280	COG2960	long-chain fatty acid transporting porin activity
FLM25_RS02305	COG3025	triphosphatase activity
FLM25_RS02310	COG4991	sh3 domain protein
FLM25_RS02325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FLM25_RS02390	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FLM25_RS02395	COG0358	DNA primase activity
FLM25_RS02400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLM25_RS02425	COG2197	response regulator
FLM25_RS02430	COG2205	protein histidine kinase activity
FLM25_RS02430	COG0784	Response regulator, receiver
FLM25_RS02430	COG2198	Histidine kinase
FLM25_RS02430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM25_RS02440	COG3247	response to pH
FLM25_RS02510	COG2376	Dihydroxyacetone kinase
FLM25_RS02515	COG1461	Dihydroxyacetone kinase
FLM25_RS02530	COG2375	cellular response to nickel ion
FLM25_RS02535	COG1695	Transcriptional regulator
FLM25_RS02585	COG0446	pyridine nucleotide-disulphide oxidoreductase
FLM25_RS02585	COG1902	pentaerythritol trinitrate reductase activity
FLM25_RS02605	COG1451	nucleotide metabolic process
FLM25_RS02610	COG0673	inositol 2-dehydrogenase activity
FLM25_RS02615	COG0861	Integral membrane protein TerC family
FLM25_RS02630	COG2721	sulfolactate sulfo-lyase activity
FLM25_RS02640	COG2271	Major facilitator Superfamily
FLM25_RS02645	COG2186	Transcriptional regulator
FLM25_RS02650	COG0586	Pfam SNARE associated Golgi protein
FLM25_RS02660	COG1422	Protein of unknown function (DUF1090)
FLM25_RS02665	COG4575	ribosome binding
FLM25_RS02670	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FLM25_RS02680	COG2259	Doxx family
FLM25_RS02685	COG0435	Glutathione S-transferase
FLM25_RS02690	COG3152	Membrane
FLM25_RS02695	COG0583	DNA-binding transcription factor activity
FLM25_RS02700	COG1741	Belongs to the pirin family
FLM25_RS02725	COG1929	Belongs to the glycerate kinase type-1 family
FLM25_RS02730	COG2084	Dehydrogenase
FLM25_RS02740	COG2271	Major facilitator Superfamily
FLM25_RS02745	COG2721	sulfolactate sulfo-lyase activity
FLM25_RS02750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLM25_RS02755	COG1349	DNA-binding transcription factor activity
FLM25_RS02765	COG1105	Belongs to the carbohydrate kinase PfkB family
FLM25_RS02770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS02770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLM25_RS02770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLM25_RS02775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS02775	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS02785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS02790	COG3414	Phosphotransferase system galactitol-specific IIB component
FLM25_RS02795	COG3775	system Galactitol-specific IIC component
FLM25_RS02800	COG1063	alcohol dehydrogenase
FLM25_RS02825	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FLM25_RS02845	COG2823	Periplasmic or secreted lipoprotein
FLM25_RS02850	COG0701	Predicted permease
FLM25_RS02855	COG0702	epimerase
FLM25_RS02860	COG0693	protein deglycase activity
FLM25_RS02875	COG3153	acetyltransferase
FLM25_RS02880	COG3154	lipid carrier protein
FLM25_RS02885	COG0826	peptidase U32
FLM25_RS02890	COG0826	peptidase U32
FLM25_RS02895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLM25_RS02900	COG0814	amino acid
FLM25_RS02945	COG0195	Participates in both transcription termination and antitermination
FLM25_RS02985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLM25_RS02995	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FLM25_RS03000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FLM25_RS03010	COG1534	Rna-binding protein
FLM25_RS03020	COG2027	D-alanyl-D-alanine carboxypeptidase
FLM25_RS03030	COG0697	spore germination
FLM25_RS03045	COG0142	geranyltranstransferase activity
FLM25_RS03050	COG3423	Transcriptional regulator
FLM25_RS03060	COG5007	Belongs to the BolA IbaG family
FLM25_RS03065	COG3113	response to antibiotic
FLM25_RS03070	COG2854	intermembrane phospholipid transfer
FLM25_RS03075	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FLM25_RS03080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FLM25_RS03085	COG1127	ABC transporter
FLM25_RS03090	COG0530	calcium, potassium:sodium antiporter activity
FLM25_RS03100	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FLM25_RS03105	COG3117	lipopolysaccharide transmembrane transporter activity
FLM25_RS03110	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FLM25_RS03115	COG1137	ATPase activity
FLM25_RS03120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FLM25_RS03125	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FLM25_RS03130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS03140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS03145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLM25_RS03150	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FLM25_RS03155	COG5002	protein histidine kinase activity
FLM25_RS03155	COG0784	Response regulator, receiver
FLM25_RS03155	COG2198	Histidine kinase
FLM25_RS03160	COG1312	Catalyzes the dehydration of D-mannonate
FLM25_RS03165	COG1063	alcohol dehydrogenase
FLM25_RS03170	COG2271	Major facilitator Superfamily
FLM25_RS03175	COG1242	4 iron, 4 sulfur cluster binding
FLM25_RS03180	COG0067	glutamate synthase
FLM25_RS03180	COG0070	glutamate synthase
FLM25_RS03180	COG0069	glutamate synthase activity
FLM25_RS03185	COG0493	'glutamate synthase
FLM25_RS03195	COG2969	positive regulation of protein catabolic process
FLM25_RS03200	COG0625	glutathione transferase activity
FLM25_RS03220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FLM25_RS03225	COG3105	Protein conserved in bacteria
FLM25_RS03230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLM25_RS03235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLM25_RS03260	COG2732	(Barnase) inhibitor
FLM25_RS03265	COG1289	transmembrane transporter activity
FLM25_RS03280	COG0583	DNA-binding transcription factor activity
FLM25_RS03285	COG0312	modulator of DNA gyrase
FLM25_RS03290	COG3164	Protein of unknown function
FLM25_RS03295	COG1530	ribonuclease E activity
FLM25_RS03305	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FLM25_RS03310	COG1792	Involved in formation and maintenance of cell shape
FLM25_RS03315	COG1077	Cell shape determining protein MreB Mrl
FLM25_RS03320	COG2199	diguanylate cyclase activity
FLM25_RS03320	COG2200	EAL domain
FLM25_RS03345	COG0511	ligase activity, forming carbon-carbon bonds
FLM25_RS03350	COG0439	Biotin carboxylase
FLM25_RS03355	COG3924	membrane
FLM25_RS03360	COG4145	pantothenate transmembrane transporter activity
FLM25_RS03385	COG4626	Terminase
FLM25_RS03385	COG1802	Transcriptional regulator
FLM25_RS03470	COG3561	AntA/AntB antirepressor
FLM25_RS03485	COG0582	viral genome integration into host DNA
FLM25_RS03490	COG1309	transcriptional regulator
FLM25_RS03495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLM25_RS03500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLM25_RS03535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FLM25_RS03555	COG0551	DNA topoisomerase type I activity
FLM25_RS03565	COG0758	DNA mediated transformation
FLM25_RS03595	COG3036	rescue of stalled ribosome
FLM25_RS03600	COG0789	Transcriptional regulator
FLM25_RS03615	COG0202	RNA polymerase activity
FLM25_RS03640	COG0201	protein transport
FLM25_RS03705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FLM25_RS03720	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FLM25_RS03745	COG0051	transcription antitermination factor activity, RNA binding
FLM25_RS03800	COG2964	Protein conserved in bacteria
FLM25_RS03805	COG0545	Peptidyl-prolyl cis-trans isomerase
FLM25_RS03815	COG1047	Peptidyl-prolyl cis-trans
FLM25_RS03820	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FLM25_RS03835	COG0488	(ABC) transporter
FLM25_RS03840	COG0429	hydrolase of the alpha beta-hydrolase fold
FLM25_RS03850	COG3954	Phosphoribulokinase
FLM25_RS03855	COG1765	OsmC-like protein
FLM25_RS03865	COG1289	transmembrane transporter activity
FLM25_RS03870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLM25_RS03895	COG0738	Major facilitator superfamily
FLM25_RS03900	COG0402	S-adenosylhomocysteine deaminase activity
FLM25_RS03905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FLM25_RS03930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FLM25_RS03935	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FLM25_RS03940	COG3266	domain, Protein
FLM25_RS03955	COG4796	Type ii and iii secretion system protein
FLM25_RS03980	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FLM25_RS03985	COG0494	nUDIX hydrolase
FLM25_RS03995	COG1011	Hydrolase
FLM25_RS04000	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FLM25_RS04020	COG0745	RESPONSE REGULATOR receiver
FLM25_RS04025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FLM25_RS04030	COG2183	response to ionizing radiation
FLM25_RS04035	COG1918	ferrous iron import across plasma membrane
FLM25_RS04060	COG1040	competence protein
FLM25_RS04070	COG2610	gluconate transmembrane transporter activity
FLM25_RS04075	COG1640	4-alpha-glucanotransferase
FLM25_RS04080	COG0058	SHG alpha-glucan phosphorylase activity
FLM25_RS04090	COG1349	DNA-binding transcription factor activity
FLM25_RS04105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FLM25_RS04120	COG0058	SHG alpha-glucan phosphorylase activity
FLM25_RS04145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FLM25_RS04155	COG2610	gluconate transmembrane transporter activity
FLM25_RS04160	COG3265	gluconokinase activity
FLM25_RS04165	COG1609	Transcriptional regulator
FLM25_RS04170	COG1741	Belongs to the pirin family
FLM25_RS04175	COG0673	inositol 2-dehydrogenase activity
FLM25_RS04185	COG1247	-acetyltransferase
FLM25_RS04190	COG0405	Gamma-glutamyltransferase
FLM25_RS04200	COG0584	glycerophosphoryl diester phosphodiesterase
FLM25_RS04250	COG0559	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS04255	COG0683	leucine binding
FLM25_RS04265	COG0683	leucine binding
FLM25_RS04275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FLM25_RS04290	COG2177	Part of the ABC transporter FtsEX involved in
FLM25_RS04295	COG2884	Cell division ATP-binding protein ftsE
FLM25_RS04300	COG0552	protein localization to endoplasmic reticulum
FLM25_RS04305	COG0742	ribosomal rna small subunit methyltransferase
FLM25_RS04310	COG3776	membrane
FLM25_RS04320	COG3714	YhhN family
FLM25_RS04335	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FLM25_RS04345	COG0477	Major facilitator Superfamily
FLM25_RS04350	COG0628	permease
FLM25_RS04390	COG3479	Phenolic acid decarboxylase
FLM25_RS04400	COG0747	negative chemotaxis
FLM25_RS04405	COG0601	transmembrane transport
FLM25_RS04410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLM25_RS04420	COG1124	(ABC) transporter
FLM25_RS04430	COG2239	Acts as a magnesium transporter
FLM25_RS04435	COG2081	HI0933 family
FLM25_RS04440	COG0306	phosphate transporter
FLM25_RS04450	COG0589	response to stress
FLM25_RS04470	COG0671	phosphoesterase, PA-phosphatase related
FLM25_RS04475	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FLM25_RS04480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLM25_RS04490	COG1454	alcohol dehydrogenase
FLM25_RS04500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLM25_RS04505	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS04510	COG0583	DNA-binding transcription factor activity
FLM25_RS04515	COG1295	ribonuclease BN
FLM25_RS04520	COG0477	Major facilitator Superfamily
FLM25_RS04525	COG2982	Protein involved in outer membrane biogenesis
FLM25_RS04535	COG0612	Peptidase, M16
FLM25_RS04545	COG2200	EAL domain
FLM25_RS04545	COG2199	diguanylate cyclase activity
FLM25_RS04550	COG3118	belongs to the thioredoxin family
FLM25_RS04550	COG0457	Tetratricopeptide repeat
FLM25_RS04555	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FLM25_RS04560	COG1215	transferase activity, transferring glycosyl groups
FLM25_RS04590	COG2194	sulfuric ester hydrolase activity
FLM25_RS04605	COG0457	Tetratricopeptide repeat
FLM25_RS04610	COG1215	transferase activity, transferring glycosyl groups
FLM25_RS04635	COG4608	Belongs to the ABC transporter superfamily
FLM25_RS04640	COG0444	Belongs to the ABC transporter superfamily
FLM25_RS04645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLM25_RS04650	COG0601	transmembrane transport
FLM25_RS04655	COG0747	negative chemotaxis
FLM25_RS04680	COG2223	nitrite transmembrane transporter activity
FLM25_RS04685	COG5571	outer membrane autotransporter
FLM25_RS04690	COG2818	Glycosylase
FLM25_RS04695	COG0456	acetyltransferase
FLM25_RS04700	COG0243	molybdopterin cofactor binding
FLM25_RS04705	COG2885	chlorophyll binding
FLM25_RS04710	COG1609	Transcriptional regulator
FLM25_RS04720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLM25_RS04740	COG2814	Major facilitator Superfamily
FLM25_RS04745	COG2944	sequence-specific DNA binding
FLM25_RS04750	COG1278	Cold shock
FLM25_RS04780	COG3274	enterobacterial common antigen metabolic process
FLM25_RS04785	COG4682	membrane
FLM25_RS04790	COG4682	membrane
FLM25_RS04805	COG4213	ABC transporter substrate-binding protein
FLM25_RS04815	COG4214	carbohydrate transport
FLM25_RS04820	COG1609	Transcriptional regulator
FLM25_RS04820	COG2207	Transcriptional regulator
FLM25_RS04825	COG2992	FlgJ-related protein
FLM25_RS04830	COG0366	Alpha amylase catalytic
FLM25_RS04835	COG3977	Valine--pyruvate aminotransferase
FLM25_RS04840	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FLM25_RS04845	COG1414	Transcriptional regulator
FLM25_RS04850	COG3276	selenocysteine insertion sequence binding
FLM25_RS04860	COG0625	glutathione transferase activity
FLM25_RS04865	COG1566	PFAM secretion protein HlyD family protein
FLM25_RS04885	COG3722	fumarate hydratase activity
FLM25_RS04905	COG2186	Transcriptional regulator
FLM25_RS04915	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FLM25_RS04935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FLM25_RS04940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLM25_RS04950	COG4942	peptidase
FLM25_RS04955	COG2861	carbohydrate metabolic process
FLM25_RS04960	COG0463	Glycosyl transferase, family 2
FLM25_RS04970	COG0156	8-amino-7-oxononanoate synthase activity
FLM25_RS04985	COG0859	PFAM glycosyl transferase family 9
FLM25_RS05010	COG0859	PFAM glycosyl transferase family 9
FLM25_RS05020	COG0438	transferase activity, transferring glycosyl groups
FLM25_RS05025	COG1216	Glycosyl transferase, family 2
FLM25_RS05030	COG1519	Transferase
FLM25_RS05065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FLM25_RS05090	COG0842	Transport permease protein
FLM25_RS05095	COG1131	(ABC) transporter
FLM25_RS05115	COG1561	YicC-like family, N-terminal region
FLM25_RS05120	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FLM25_RS05125	COG2169	Transcriptional regulator
FLM25_RS05125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FLM25_RS05135	COG2860	membrane
FLM25_RS05155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLM25_RS05160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLM25_RS05165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FLM25_RS05170	COG1494	fructose-1,6-bisphosphatase
FLM25_RS05180	COG3152	Membrane
FLM25_RS05205	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FLM25_RS05225	COG0786	glutamate:sodium symporter activity
FLM25_RS05230	COG2233	PERMEase
FLM25_RS05240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLM25_RS05240	COG1263	PTS System
FLM25_RS05245	COG1486	melibiose metabolic process
FLM25_RS05255	COG1501	Belongs to the glycosyl hydrolase 31 family
FLM25_RS05260	COG2211	Major facilitator Superfamily
FLM25_RS05290	COG1064	alcohol dehydrogenase
FLM25_RS05300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FLM25_RS05315	COG1464	Belongs to the NlpA lipoprotein family
FLM25_RS05340	COG0583	DNA-binding transcription factor activity
FLM25_RS05375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLM25_RS05385	COG2814	Major facilitator Superfamily
FLM25_RS05395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLM25_RS05395	COG1263	PTS System
FLM25_RS05400	COG0697	spore germination
FLM25_RS05415	COG2828	Protein conserved in bacteria
FLM25_RS05420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FLM25_RS05425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FLM25_RS05430	COG0583	DNA-binding transcription factor activity
FLM25_RS05435	COG3384	dioxygenase
FLM25_RS05445	COG1609	Transcriptional regulator
FLM25_RS05455	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLM25_RS05455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLM25_RS05460	COG1447	Phosphotransferase system cellobiose-specific component IIA
FLM25_RS05465	COG4580	involved in the transport of maltose and maltodextrins
FLM25_RS05490	COG2188	Transcriptional regulator
FLM25_RS05530	COG2271	Major facilitator Superfamily
FLM25_RS05540	COG2197	response regulator
FLM25_RS05545	COG0440	acetolactate synthase activity
FLM25_RS05550	COG0028	Belongs to the TPP enzyme family
FLM25_RS05580	COG2814	Major facilitator Superfamily
FLM25_RS05585	COG0583	DNA-binding transcription factor activity
FLM25_RS05595	COG2610	gluconate transmembrane transporter activity
FLM25_RS05615	COG2149	membrane
FLM25_RS05630	COG2188	Transcriptional regulator
FLM25_RS05640	COG3645	SOS response
FLM25_RS05655	COG5645	(Lipo)protein
FLM25_RS05660	COG0823	Involved in the tonB-independent uptake of proteins
FLM25_RS05665	COG2271	Major facilitator Superfamily
FLM25_RS05675	COG0800	Aldolase
FLM25_RS05680	COG3734	2-keto-3-deoxy-galactonokinase
FLM25_RS05685	COG2186	Transcriptional regulator
FLM25_RS05700	COG0561	phosphatase activity
FLM25_RS05705	COG0187	DNA topoisomerase II activity
FLM25_RS05735	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FLM25_RS05765	COG2091	lysine biosynthetic process via aminoadipic acid
FLM25_RS05770	COG0431	NADPH-dependent FMN reductase
FLM25_RS05775	COG2252	PERMEase
FLM25_RS05780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FLM25_RS05785	COG0363	glucosamine-6-phosphate deaminase activity
FLM25_RS05790	COG2382	esterase
FLM25_RS05800	COG0704	Plays a role in the regulation of phosphate uptake
FLM25_RS05805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FLM25_RS05810	COG0581	inorganic phosphate transmembrane transporter activity
FLM25_RS05815	COG0573	inorganic phosphate transmembrane transporter activity
FLM25_RS05820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FLM25_RS05825	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FLM25_RS05875	COG3312	ion transport
FLM25_RS05890	COG0716	FMN binding
FLM25_RS05895	COG1522	sequence-specific DNA binding
FLM25_RS05925	COG1129	ABC transporter
FLM25_RS05930	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS05940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLM25_RS05945	COG1609	Transcriptional regulator
FLM25_RS05950	COG0477	Major facilitator Superfamily
FLM25_RS05955	COG2186	Transcriptional regulator
FLM25_RS05980	COG1763	Mo-molybdopterin cofactor biosynthetic process
FLM25_RS05990	COG3084	Protein conserved in bacteria
FLM25_RS05995	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FLM25_RS06005	COG0204	Acyl-transferase
FLM25_RS06025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FLM25_RS06040	COG3852	Histidine kinase
FLM25_RS06055	COG1011	Hydrolase
FLM25_RS06070	COG0456	acetyltransferase
FLM25_RS06080	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FLM25_RS06095	COG2864	formate dehydrogenase
FLM25_RS06100	COG0437	4 iron, 4 sulfur cluster binding
FLM25_RS06120	COG0205	6-phosphofructokinase activity
FLM25_RS06180	COG2211	Major facilitator Superfamily
FLM25_RS06190	COG1454	alcohol dehydrogenase
FLM25_RS06195	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS06200	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS06205	COG1129	ABC transporter
FLM25_RS06245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FLM25_RS06250	COG2258	MOSC domain
FLM25_RS06255	COG2205	protein histidine kinase activity
FLM25_RS06260	COG0745	RESPONSE REGULATOR receiver
FLM25_RS06265	COG3678	ATP-independent chaperone mediated protein folding
FLM25_RS06285	COG1575	Belongs to the MenA family. Type 1 subfamily
FLM25_RS06300	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FLM25_RS06305	COG1609	Transcriptional regulator
FLM25_RS06310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FLM25_RS06325	COG0626	cystathionine gamma-synthase activity
FLM25_RS06330	COG0460	homoserine dehydrogenase
FLM25_RS06330	COG0527	aspartate kinase activity
FLM25_RS06340	COG0737	Belongs to the 5'-nucleotidase family
FLM25_RS06350	COG0583	DNA-binding transcription factor activity
FLM25_RS06360	COG0697	spore germination
FLM25_RS06365	COG0371	Dehydrogenase
FLM25_RS06375	COG2207	Transcriptional regulator
FLM25_RS06380	COG3443	Belongs to the bacterial solute-binding protein 9 family
FLM25_RS06395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FLM25_RS06410	COG0583	DNA-binding transcription factor activity
FLM25_RS06485	COG3085	chromosome segregation
FLM25_RS06505	COG3978	acetolactate synthase activity
FLM25_RS06520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FLM25_RS06525	COG0583	DNA-binding transcription factor activity
FLM25_RS06535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FLM25_RS06540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FLM25_RS06550	COG1811	Na channel or pump
FLM25_RS06575	COG3118	belongs to the thioredoxin family
FLM25_RS06580	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FLM25_RS06585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLM25_RS06595	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FLM25_RS06600	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FLM25_RS06605	COG1088	dTDP-glucose 4,6-dehydratase activity
FLM25_RS06610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FLM25_RS06615	COG0456	acetyltransferase
FLM25_RS06620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FLM25_RS06625	COG2244	polysaccharide biosynthetic process
FLM25_RS06670	COG3071	HemY protein
FLM25_RS06675	COG2959	enzyme of heme biosynthesis
FLM25_RS06690	COG3072	Adenylate cyclase
FLM25_RS06720	COG1011	Hydrolase
FLM25_RS06725	COG0210	DNA helicase
FLM25_RS06755	COG1280	lysine exporter protein (LysE YggA)
FLM25_RS06765	COG1280	lysine exporter protein (LysE YggA)
FLM25_RS06770	COG2267	carboxylic ester hydrolase activity
FLM25_RS06775	COG0561	phosphatase activity
FLM25_RS06780	COG0697	spore germination
FLM25_RS06785	COG0583	DNA-binding transcription factor activity
FLM25_RS06815	COG3165	ubiquinone biosynthetic process from chorismate
FLM25_RS06835	COG0805	protein transport
FLM25_RS06875	COG1739	Uncharacterized protein family UPF0029
FLM25_RS06885	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FLM25_RS06915	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FLM25_RS06960	COG0250	Participates in transcription elongation, termination and antitermination
FLM25_RS06995	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FLM25_RS07000	COG1447	Phosphotransferase system cellobiose-specific component IIA
FLM25_RS07010	COG3706	GGDEF domain
FLM25_RS07025	COG2104	thiamine diphosphate biosynthetic process
FLM25_RS07030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FLM25_RS07045	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FLM25_RS07080	COG3678	ATP-independent chaperone mediated protein folding
FLM25_RS07085	COG4191	Histidine kinase
FLM25_RS07095	COG0151	Belongs to the GarS family
FLM25_RS07125	COG0456	acetyltransferase
FLM25_RS07135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FLM25_RS07165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FLM25_RS07220	COG0527	aspartate kinase activity
FLM25_RS07230	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FLM25_RS07240	COG0251	oxidation-reduction process
FLM25_RS07310	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FLM25_RS07320	COG0534	Mate efflux family protein
FLM25_RS07330	COG3237	CsbD-like
FLM25_RS07335	COG0735	belongs to the Fur family
FLM25_RS07345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLM25_RS07360	COG0305	Participates in initiation and elongation during chromosome replication
FLM25_RS07365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FLM25_RS07380	COG0432	Pfam Uncharacterised protein family UPF0047
FLM25_RS07385	COG2315	Protein conserved in bacteria
FLM25_RS07400	COG0741	lytic transglycosylase activity
FLM25_RS07405	COG4771	TonB-dependent receptor
FLM25_RS07425	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FLM25_RS07435	COG0483	inositol monophosphate 1-phosphatase activity
FLM25_RS07440	COG1609	Transcriptional regulator
FLM25_RS07445	COG1234	tRNA 3'-trailer cleavage
FLM25_RS07475	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FLM25_RS07485	COG0789	Transcriptional regulator
FLM25_RS07490	COG0625	glutathione transferase activity
FLM25_RS07495	COG2252	PERMEase
FLM25_RS07500	COG0025	NhaP-type Na H and K H
FLM25_RS07505	COG0583	DNA-binding transcription factor activity
FLM25_RS07510	COG1380	Effector of murein hydrolase LrgA
FLM25_RS07515	COG1346	cytolysis
FLM25_RS07520	COG3539	Fimbrial protein
FLM25_RS07550	COG3162	membrane
FLM25_RS07555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FLM25_RS07565	COG1301	dicarboxylic acid transport
FLM25_RS07570	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FLM25_RS07605	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS07610	COG1129	ABC transporter
FLM25_RS07615	COG0784	Response regulator, receiver
FLM25_RS07615	COG4191	Histidine kinase
FLM25_RS07625	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FLM25_RS07635	COG3454	Phosphonate metabolism
FLM25_RS07640	COG4778	phosphonate C-P lyase system protein PhnL
FLM25_RS07645	COG4107	phosphonate C-P lyase system protein PhnK
FLM25_RS07650	COG3627	carbon phosphorus lyase activity
FLM25_RS07655	COG3626	phosphonate metabolism
FLM25_RS07660	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FLM25_RS07665	COG3624	Phosphonate C-P lyase system protein PhnG
FLM25_RS07670	COG2188	Transcriptional regulator
FLM25_RS07675	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FLM25_RS07680	COG2824	Alkylphosphonate utilization operon protein PhnA
FLM25_RS07690	COG2169	Transcriptional regulator
FLM25_RS07695	COG1486	melibiose metabolic process
FLM25_RS07740	COG0861	Integral membrane protein TerC family
FLM25_RS07755	COG1215	transferase activity, transferring glycosyl groups
FLM25_RS07760	COG0726	polysaccharide deacetylase
FLM25_RS07760	COG1649	PFAM Uncharacterised BCR, COG1649
FLM25_RS07765	COG0457	Tetratricopeptide repeat
FLM25_RS07800	COG1309	transcriptional regulator
FLM25_RS07815	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FLM25_RS07820	COG1027	Aspartate ammonia-lyase
FLM25_RS07825	COG3030	protein affecting phage T7 exclusion by the F plasmid
FLM25_RS07830	COG0531	amino acid
FLM25_RS07910	COG1509	lysine 2,3-aminomutase activity
FLM25_RS07925	COG5510	response to toxic substance
FLM25_RS07930	COG2076	Multidrug Resistance protein
FLM25_RS07950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FLM25_RS07955	COG1053	succinate dehydrogenase
FLM25_RS07970	COG3264	Mechanosensitive ion channel
FLM25_RS07970	COG1511	domain protein
FLM25_RS07990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM25_RS08005	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FLM25_RS08010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FLM25_RS08010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FLM25_RS08015	COG0802	atpase or kinase
FLM25_RS08020	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLM25_RS08040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FLM25_RS08045	COG0330	HflC and HflK could
FLM25_RS08050	COG0330	HflC and HflK could
FLM25_RS08060	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FLM25_RS08075	COG0557	exoribonuclease II activity
FLM25_RS08080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLM25_RS08085	COG1960	acyl-CoA dehydrogenase activity
FLM25_RS08095	COG3650	response to hydrogen peroxide
FLM25_RS08100	COG1073	alpha beta
FLM25_RS08160	COG2965	DNA replication, synthesis of RNA primer
FLM25_RS08165	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FLM25_RS08175	COG3061	Opacity-associated protein A
FLM25_RS08180	COG0545	Peptidyl-prolyl cis-trans isomerase
FLM25_RS08185	COG1113	amino acid transport
FLM25_RS08195	COG0697	spore germination
FLM25_RS08205	COG0702	epimerase
FLM25_RS08210	COG1733	regulation of RNA biosynthetic process
FLM25_RS08225	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FLM25_RS08240	COG1253	flavin adenine dinucleotide binding
FLM25_RS08250	COG0729	surface antigen
FLM25_RS08255	COG2911	Protein conserved in bacteria
FLM25_RS08260	COG2105	PFAM AIG2 family protein
FLM25_RS08280	COG1879	ABC-type sugar transport system periplasmic component
FLM25_RS08285	COG1129	ABC transporter
FLM25_RS08290	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS08295	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS08305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FLM25_RS08330	COG0312	modulator of DNA gyrase
FLM25_RS08370	COG3964	amidohydrolase
FLM25_RS08385	COG2706	6-phosphogluconolactonase activity
FLM25_RS08390	COG3711	transcriptional antiterminator
FLM25_RS08390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS08395	COG3077	Addiction module antitoxin, RelB DinJ family
FLM25_RS08400	COG2026	Addiction module toxin, RelE StbE family
FLM25_RS08405	COG0602	queuosine metabolic process
FLM25_RS08430	COG1486	melibiose metabolic process
FLM25_RS08435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLM25_RS08440	COG0366	Alpha amylase catalytic
FLM25_RS08445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLM25_RS08445	COG1263	PTS System
FLM25_RS08480	COG2731	YhcH YjgK YiaL family protein
FLM25_RS08485	COG2222	sugar isomerase
FLM25_RS08490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLM25_RS08495	COG1228	amidohydrolase
FLM25_RS08500	COG1288	antiporter activity
FLM25_RS08505	COG2188	Transcriptional regulator
FLM25_RS08530	COG0525	valine-tRNA ligase activity
FLM25_RS08535	COG2927	DNA polymerase III (CHI subunit)
FLM25_RS08545	COG0795	lipopolysaccharide-transporting ATPase activity
FLM25_RS08550	COG0795	lipopolysaccharide-transporting ATPase activity
FLM25_RS08555	COG0433	COG0433 Predicted ATPase
FLM25_RS08570	COG3718	enzyme involved in inositol metabolism
FLM25_RS08575	COG1737	Transcriptional regulator
FLM25_RS08575	COG0837	glucose binding
FLM25_RS08580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLM25_RS08585	COG3962	Belongs to the TPP enzyme family
FLM25_RS08595	COG1082	Xylose isomerase domain protein TIM barrel
FLM25_RS08605	COG1653	transport
FLM25_RS08610	COG3842	ATPase activity
FLM25_RS08615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FLM25_RS08620	COG0395	ABC-type sugar transport system, permease component
FLM25_RS08625	COG1175	transmembrane transport
FLM25_RS08630	COG1064	alcohol dehydrogenase
FLM25_RS08635	COG0659	secondary active sulfate transmembrane transporter activity
FLM25_RS08640	COG0288	reversible hydration of carbon dioxide
FLM25_RS08650	COG0582	viral genome integration into host DNA
FLM25_RS08750	COG3507	Belongs to the glycosyl hydrolase 43 family
FLM25_RS08755	COG2211	Major facilitator Superfamily
FLM25_RS08765	COG4580	involved in the transport of maltose and maltodextrins
FLM25_RS08770	COG3272	Protein of unknown function (DUF1722)
FLM25_RS08790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FLM25_RS08805	COG0300	oxidoreductase activity
FLM25_RS08815	COG0789	Transcriptional regulator
FLM25_RS08820	COG3040	lipid binding
FLM25_RS08830	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLM25_RS08835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLM25_RS08840	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLM25_RS08845	COG1538	Outer membrane efflux protein
FLM25_RS08850	COG0745	RESPONSE REGULATOR receiver
FLM25_RS08855	COG5002	protein histidine kinase activity
FLM25_RS08870	COG2850	peptidyl-arginine hydroxylation
FLM25_RS08900	COG0842	Transport permease protein
FLM25_RS08905	COG1129	ABC transporter
FLM25_RS08905	COG0842	Transport permease protein
FLM25_RS08910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLM25_RS08920	COG1879	ABC-type sugar transport system periplasmic component
FLM25_RS08925	COG1129	ABC transporter
FLM25_RS08930	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS08940	COG2249	NAD(P)H dehydrogenase (quinone) activity
FLM25_RS08945	COG0583	DNA-binding transcription factor activity
FLM25_RS08955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLM25_RS08960	COG5457	Domain of unknown function (DUF1127)
FLM25_RS08970	COG1566	PFAM secretion protein HlyD family protein
FLM25_RS08985	COG1924	4 iron, 4 sulfur cluster binding
FLM25_RS08990	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FLM25_RS09005	COG2733	membrane
FLM25_RS09015	COG1917	Cupin 2, conserved barrel domain protein
FLM25_RS09015	COG2207	Transcriptional regulator
FLM25_RS09020	COG5464	transposase or invertase
FLM25_RS09025	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS09035	COG0523	cobalamin synthesis protein
FLM25_RS09040	COG2879	small protein
FLM25_RS09045	COG1966	Carbon starvation protein
FLM25_RS09060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FLM25_RS09065	COG2368	4-hydroxyphenylacetate
FLM25_RS09085	COG3971	2-oxopent-4-enoate hydratase activity
FLM25_RS09095	COG3384	dioxygenase
FLM25_RS09100	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS09110	COG0179	Fumarylacetoacetate (FAA) hydrolase
FLM25_RS09120	COG1846	Transcriptional regulator
FLM25_RS09150	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FLM25_RS09165	COG3734	2-keto-3-deoxy-galactonokinase
FLM25_RS09170	COG0800	Aldolase
FLM25_RS09175	COG1737	Transcriptional regulator
FLM25_RS09185	COG0456	acetyltransferase
FLM25_RS09185	COG1214	PFAM Peptidase M22, glycoprotease
FLM25_RS09190	COG2271	Major facilitator Superfamily
FLM25_RS09195	COG1802	Transcriptional regulator
FLM25_RS09200	COG1063	alcohol dehydrogenase
FLM25_RS09210	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FLM25_RS09210	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FLM25_RS09225	COG3715	PTS system
FLM25_RS09230	COG3716	PTS system mannose fructose sorbose family IID component
FLM25_RS09235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FLM25_RS09245	COG5464	transposase or invertase
FLM25_RS09260	COG1484	DNA-dependent DNA replication
FLM25_RS09275	COG2966	Psort location CytoplasmicMembrane, score
FLM25_RS09290	COG2197	response regulator
FLM25_RS09295	COG2197	response regulator
FLM25_RS09300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FLM25_RS09305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLM25_RS09305	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLM25_RS09310	COG4114	ferric iron reductase
FLM25_RS09315	COG3706	GGDEF domain
FLM25_RS09350	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FLM25_RS09355	COG0456	acetyltransferase
FLM25_RS09360	COG1011	Hydrolase
FLM25_RS09370	COG2823	Periplasmic or secreted lipoprotein
FLM25_RS09380	COG4667	esterase of the alpha-beta hydrolase superfamily
FLM25_RS09385	COG0084	hydrolase, TatD family'
FLM25_RS09390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLM25_RS09420	COG3726	membrane protein affecting hemolysin expression
FLM25_RS09425	COG0560	Phosphoserine phosphatase
FLM25_RS09430	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FLM25_RS09440	COG0488	(ABC) transporter
FLM25_RS09445	COG0741	lytic transglycosylase activity
FLM25_RS09465	COG2207	Transcriptional regulator
FLM25_RS09465	COG3708	Transcriptional regulator
FLM25_RS09470	COG3045	CreA protein
FLM25_RS09475	COG0745	RESPONSE REGULATOR receiver
FLM25_RS09480	COG2205	protein histidine kinase activity
FLM25_RS09485	COG4452	Inner membrane protein CreD
FLM25_RS09490	COG0745	RESPONSE REGULATOR receiver
FLM25_RS09500	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FLM25_RS09510	COG0460	homoserine dehydrogenase
FLM25_RS09510	COG0527	aspartate kinase activity
FLM25_RS09520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FLM25_RS09535	COG1115	amino acid carrier protein
FLM25_RS09540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FLM25_RS09545	COG0521	Mo-molybdopterin cofactor biosynthetic process
FLM25_RS09550	COG0477	Major facilitator Superfamily
FLM25_RS09555	COG1584	GPR1 FUN34 yaaH family protein
FLM25_RS09560	COG4735	regulation of single-species biofilm formation
FLM25_RS09585	COG0583	DNA-binding transcription factor activity
FLM25_RS09595	COG0196	riboflavin kinase activity
FLM25_RS09610	COG1047	Peptidyl-prolyl cis-trans
FLM25_RS09635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FLM25_RS09700	COG0505	Belongs to the CarA family
FLM25_RS09745	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FLM25_RS09755	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FLM25_RS09760	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FLM25_RS09775	COG3493	citrate carrier protein
FLM25_RS09785	COG0564	pseudouridine synthase activity
FLM25_RS09795	COG0417	DNA replication proofreading
FLM25_RS09800	COG0235	Class ii aldolase
FLM25_RS09820	COG0586	Pfam SNARE associated Golgi protein
FLM25_RS09830	COG1178	ABC-type Fe3 transport system permease component
FLM25_RS09850	COG2814	Major facilitator Superfamily
FLM25_RS09855	COG2271	Major facilitator Superfamily
FLM25_RS09860	COG0583	DNA-binding transcription factor activity
FLM25_RS09870	COG0738	Major facilitator superfamily
FLM25_RS09915	COG0028	Belongs to the TPP enzyme family
FLM25_RS09925	COG1609	Transcriptional regulator
FLM25_RS09945	COG0768	penicillin binding
FLM25_RS09950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FLM25_RS09955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FLM25_RS09970	COG0772	Belongs to the SEDS family
FLM25_RS09995	COG0849	cell division
FLM25_RS10000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FLM25_RS10020	COG0494	nUDIX hydrolase
FLM25_RS10045	COG1459	type II secretion system
FLM25_RS10050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FLM25_RS10055	COG4969	Belongs to the N-Me-Phe pilin family
FLM25_RS10065	COG3023	N-Acetylmuramoyl-L-alanine amidase
FLM25_RS10070	COG3725	Membrane protein required for beta-lactamase induction
FLM25_RS10075	COG3940	Belongs to the glycosyl hydrolase 43 family
FLM25_RS10080	COG2211	Major facilitator Superfamily
FLM25_RS10085	COG1113	amino acid transport
FLM25_RS10090	COG2186	Transcriptional regulator
FLM25_RS10095	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FLM25_RS10100	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLM25_RS10105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLM25_RS10120	COG3064	Membrane
FLM25_RS10170	COG2132	Multicopper oxidase
FLM25_RS10175	COG4993	Dehydrogenase
FLM25_RS10190	COG0288	reversible hydration of carbon dioxide
FLM25_RS10195	COG1131	(ABC) transporter
FLM25_RS10200	COG0842	Transport permease protein
FLM25_RS10205	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS10210	COG0726	polysaccharide deacetylase
FLM25_RS10230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FLM25_RS10235	COG0617	tRNA 3'-terminal CCA addition
FLM25_RS10255	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FLM25_RS10260	COG1643	Atp-dependent helicase
FLM25_RS10355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLM25_RS10360	COG4774	siderophore transport
FLM25_RS10365	COG1120	ATPase activity
FLM25_RS10370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLM25_RS10375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLM25_RS10395	COG2860	membrane
FLM25_RS10415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLM25_RS10420	COG3835	regulator
FLM25_RS10435	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FLM25_RS10440	COG0024	Methionine aminopeptidase
FLM25_RS10465	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FLM25_RS10475	COG0575	Belongs to the CDS family
FLM25_RS10480	COG0750	zinc metalloprotease
FLM25_RS10490	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FLM25_RS10535	COG0346	lactoylglutathione lyase activity
FLM25_RS10545	COG4568	rho-dependent transcription termination
FLM25_RS10560	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FLM25_RS10565	COG3015	lipoprotein NlpE involved in copper resistance
FLM25_RS10570	COG0791	NLP P60 protein
FLM25_RS10580	COG1720	tRNA m6t6A37 methyltransferase activity
FLM25_RS10590	COG1464	Belongs to the NlpA lipoprotein family
FLM25_RS10595	COG2011	ABC-type metal ion transport system permease component
FLM25_RS10605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FLM25_RS10640	COG0656	L-ascorbic acid biosynthetic process
FLM25_RS10645	COG0583	DNA-binding transcription factor activity
FLM25_RS10650	COG2814	Major facilitator Superfamily
FLM25_RS10660	COG2226	methyltransferase
FLM25_RS10665	COG0741	lytic transglycosylase activity
FLM25_RS10665	COG1388	LysM domain
FLM25_RS10675	COG2226	methyltransferase
FLM25_RS10685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FLM25_RS10695	COG0583	DNA-binding transcription factor activity
FLM25_RS10705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLM25_RS10710	COG1960	acyl-CoA dehydrogenase activity
FLM25_RS10720	COG0121	glutamine amidotransferase
FLM25_RS10725	COG3034	peptidoglycan biosynthetic process
FLM25_RS10740	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FLM25_RS10745	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FLM25_RS10760	COG2991	Protein conserved in bacteria
FLM25_RS10775	COG0454	-acetyltransferase
FLM25_RS10780	COG2195	Cleaves the N-terminal amino acid of tripeptides
FLM25_RS10800	COG1802	Transcriptional regulator
FLM25_RS10805	COG1113	amino acid transport
FLM25_RS10810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FLM25_RS10815	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS10820	COG0579	oxidoreductase
FLM25_RS10835	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FLM25_RS10840	COG0625	glutathione transferase activity
FLM25_RS10845	COG3775	system Galactitol-specific IIC component
FLM25_RS10850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLM25_RS10855	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS10860	COG1070	Carbohydrate kinase
FLM25_RS10880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLM25_RS10885	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLM25_RS10890	COG0022	dehydrogenase e1 component
FLM25_RS10895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FLM25_RS10955	COG1192	Involved in chromosome partitioning
FLM25_RS10960	COG0582	viral genome integration into host DNA
FLM25_RS10985	COG0791	NLP P60 protein
FLM25_RS11005	COG3639	organic phosphonate transmembrane transporter activity
FLM25_RS11015	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FLM25_RS11040	COG3188	usher protein
FLM25_RS11055	COG0765	amino acid transport
FLM25_RS11060	COG0765	amino acid transport
FLM25_RS11065	COG1126	abc transporter atp-binding protein
FLM25_RS11070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM25_RS11110	COG4302	ethanolamine ammonia-lyase activity
FLM25_RS11115	COG4303	Ethanolamine ammonia lyase large subunit
FLM25_RS11130	COG0833	amino acid
FLM25_RS11135	COG2040	homocysteine
FLM25_RS11140	COG4521	taurine ABC transporter
FLM25_RS11145	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FLM25_RS11150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLM25_RS11155	COG2175	clavaminate synthase activity
FLM25_RS11165	COG0113	porphobilinogen synthase activity
FLM25_RS11170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FLM25_RS11175	COG1335	isochorismatase
FLM25_RS11180	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FLM25_RS11220	COG1785	Belongs to the alkaline phosphatase family
FLM25_RS11230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLM25_RS11240	COG3416	Protein conserved in bacteria
FLM25_RS11245	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FLM25_RS11255	COG4126	flavin adenine dinucleotide binding
FLM25_RS11270	COG1940	carbohydrate kinase activity
FLM25_RS11275	COG0419	ATPase involved in DNA repair
FLM25_RS11280	COG0420	3'-5' exonuclease activity
FLM25_RS11305	COG0366	Alpha amylase catalytic
FLM25_RS11310	COG0583	DNA-binding transcription factor activity
FLM25_RS11315	COG1335	isochorismatase
FLM25_RS11325	COG1228	amidohydrolase
FLM25_RS11335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLM25_RS11350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS11360	COG0450	alkyl hydroperoxide reductase
FLM25_RS11385	COG1862	Preprotein translocase
FLM25_RS11390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLM25_RS11395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLM25_RS11415	COG4238	major outer membrane lipoprotein
FLM25_RS11425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FLM25_RS11425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FLM25_RS11445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FLM25_RS11450	COG0667	Aldo Keto reductase
FLM25_RS11460	COG0142	geranyltranstransferase activity
FLM25_RS11480	COG0693	protein deglycase activity
FLM25_RS11485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FLM25_RS11495	COG2814	Major facilitator Superfamily
FLM25_RS11500	COG0673	inositol 2-dehydrogenase activity
FLM25_RS11515	COG1053	succinate dehydrogenase
FLM25_RS11525	COG1053	succinate dehydrogenase
FLM25_RS11530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FLM25_RS11535	COG1414	Transcriptional regulator
FLM25_RS11550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FLM25_RS11555	COG1845	cytochrome c oxidase, subunit III
FLM25_RS11560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FLM25_RS11565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FLM25_RS11570	COG2223	nitrite transmembrane transporter activity
FLM25_RS11575	COG3056	Lipoprotein
FLM25_RS11580	COG0271	Belongs to the BolA IbaG family
FLM25_RS11600	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FLM25_RS11605	COG0776	regulation of translation
FLM25_RS11610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FLM25_RS11615	COG1555	photosystem II stabilization
FLM25_RS11620	COG0824	Thioesterase
FLM25_RS11630	COG4533	DNA binding
FLM25_RS11645	COG1522	sequence-specific DNA binding
FLM25_RS11650	COG1132	(ABC) transporter
FLM25_RS11655	COG1132	(ABC) transporter
FLM25_RS11660	COG0347	Belongs to the P(II) protein family
FLM25_RS11665	COG0004	ammonium transporteR
FLM25_RS11670	COG1946	Acyl-CoA thioesterase
FLM25_RS11675	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FLM25_RS11680	COG3695	enzyme binding
FLM25_RS11710	COG2364	Membrane
FLM25_RS11725	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FLM25_RS11735	COG2182	Extracellular solute-binding protein
FLM25_RS11740	COG1175	transmembrane transport
FLM25_RS11745	COG3833	ABC-type maltose transport systems, permease component
FLM25_RS11750	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FLM25_RS11755	COG1874	Beta-galactosidase
FLM25_RS11805	COG0110	maltose O-acetyltransferase activity
FLM25_RS11820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLM25_RS11825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLM25_RS11830	COG1309	transcriptional regulator
FLM25_RS11835	COG3264	Mechanosensitive ion channel
FLM25_RS11835	COG1196	nuclear chromosome segregation
FLM25_RS11840	COG5464	transposase or invertase
FLM25_RS11850	COG3923	Primosomal replication protein n
FLM25_RS11855	COG2832	Protein of unknown function (DUF454)
FLM25_RS11895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLM25_RS11900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FLM25_RS11900	COG4651	solute:proton antiporter activity
FLM25_RS11905	COG2223	nitrite transmembrane transporter activity
FLM25_RS11915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FLM25_RS11920	COG3735	TraB family
FLM25_RS11935	COG1585	Membrane protein implicated in regulation of membrane protease activity
FLM25_RS11940	COG0330	HflC and HflK could
FLM25_RS11945	COG4619	ABC transporter
FLM25_RS11950	COG0390	transport system, permease component
FLM25_RS11955	COG3118	belongs to the thioredoxin family
FLM25_RS11960	COG0300	oxidoreductase activity
FLM25_RS11965	COG2755	lipolytic protein G-D-S-L family
FLM25_RS11970	COG4181	ATPase activity
FLM25_RS11975	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FLM25_RS11995	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FLM25_RS12000	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FLM25_RS12015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FLM25_RS12025	COG2501	S4 domain
FLM25_RS12125	COG0305	Participates in initiation and elongation during chromosome replication
FLM25_RS12195	COG3772	lysozyme
FLM25_RS12385	COG3344	reverse transcriptase
FLM25_RS12435	COG3539	Fimbrial protein
FLM25_RS12440	COG3121	Chaperone
FLM25_RS12445	COG3188	usher protein
FLM25_RS12460	COG1560	Kdo2-lipid A biosynthetic process
FLM25_RS12470	COG3710	Transcriptional regulator
FLM25_RS12475	COG0531	amino acid
FLM25_RS12480	COG1982	Orn Lys Arg decarboxylase major
FLM25_RS12485	COG3104	oligopeptide transport
FLM25_RS12515	COG0673	inositol 2-dehydrogenase activity
FLM25_RS12530	COG1129	ABC transporter
FLM25_RS12535	COG4211	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS12580	COG1566	PFAM secretion protein HlyD family protein
FLM25_RS12585	COG1120	ATPase activity
FLM25_RS12590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLM25_RS12620	COG1473	amidohydrolase
FLM25_RS12625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM25_RS12630	COG0667	Aldo Keto reductase
FLM25_RS12675	COG0531	amino acid
FLM25_RS12685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLM25_RS12690	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS12705	COG1113	amino acid transport
FLM25_RS12710	COG2211	Major facilitator Superfamily
FLM25_RS12720	COG0673	inositol 2-dehydrogenase activity
FLM25_RS12730	COG2771	luxR family
FLM25_RS12745	COG3188	usher protein
FLM25_RS12775	COG0668	transmembrane transport
FLM25_RS12780	COG0477	Major facilitator Superfamily
FLM25_RS12795	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FLM25_RS12795	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FLM25_RS12800	COG2222	sugar isomerase
FLM25_RS12805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FLM25_RS12810	COG3716	PTS system mannose fructose sorbose family IID component
FLM25_RS12820	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLM25_RS12830	COG0778	Nitroreductase
FLM25_RS12835	COG2315	Protein conserved in bacteria
FLM25_RS12885	COG3698	Phosphodiester glycosidase
FLM25_RS12895	COG0697	spore germination
FLM25_RS12910	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FLM25_RS12915	COG0765	amino acid transport
FLM25_RS12920	COG4215	(ABC) transporter
FLM25_RS12930	COG4221	oxidoreductase activity
FLM25_RS12940	COG4608	Belongs to the ABC transporter superfamily
FLM25_RS12945	COG0444	Belongs to the ABC transporter superfamily
FLM25_RS12950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLM25_RS12955	COG0601	transmembrane transport
FLM25_RS12960	COG0747	negative chemotaxis
FLM25_RS12985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FLM25_RS12995	COG0668	transmembrane transport
FLM25_RS13000	COG0583	DNA-binding transcription factor activity
FLM25_RS13010	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS13020	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS13025	COG1129	ABC transporter
FLM25_RS13035	COG1879	ABC-type sugar transport system periplasmic component
FLM25_RS13040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FLM25_RS13045	COG2390	Transcriptional regulator
FLM25_RS13050	COG3959	Transketolase, thiamine diphosphate binding domain
FLM25_RS13055	COG3958	Transketolase
FLM25_RS13060	COG2977	Belongs to the P-Pant transferase superfamily
FLM25_RS13065	COG4771	TonB-dependent receptor
FLM25_RS13070	COG2382	esterase
FLM25_RS13075	COG3251	PFAM MbtH domain protein
FLM25_RS13080	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FLM25_RS13080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLM25_RS13085	COG1120	ATPase activity
FLM25_RS13090	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLM25_RS13095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLM25_RS13105	COG4592	Periplasmic binding protein
FLM25_RS13110	COG1169	isochorismate synthase
FLM25_RS13115	COG1021	2,3-dihydroxybenzoate-AMP ligase
FLM25_RS13120	COG1535	isochorismatase
FLM25_RS13120	COG3433	isochorismatase activity
FLM25_RS13125	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS13135	COG1966	Carbon starvation protein
FLM25_RS13140	COG2879	small protein
FLM25_RS13155	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS13160	COG0371	Dehydrogenase
FLM25_RS13165	COG1129	ABC transporter
FLM25_RS13170	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS13200	COG2271	Major facilitator Superfamily
FLM25_RS13205	COG0483	inositol monophosphate 1-phosphatase activity
FLM25_RS13215	COG0402	S-adenosylhomocysteine deaminase activity
FLM25_RS13225	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FLM25_RS13240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLM25_RS13250	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS13255	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS13260	COG1129	ABC transporter
FLM25_RS13285	COG0436	Aminotransferase
FLM25_RS13290	COG1475	DNA binding
FLM25_RS13295	COG3969	phosphoadenosine phosphosulfate
FLM25_RS13300	COG0583	DNA-binding transcription factor activity
FLM25_RS13305	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FLM25_RS13325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FLM25_RS13330	COG3719	Belongs to the RNase T2 family
FLM25_RS13335	COG3069	C4-dicarboxylate transmembrane transporter activity
FLM25_RS13355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLM25_RS13370	COG0583	DNA-binding transcription factor activity
FLM25_RS13385	COG1686	Belongs to the peptidase S11 family
FLM25_RS13390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FLM25_RS13395	COG0772	Belongs to the SEDS family
FLM25_RS13400	COG0768	penicillin binding
FLM25_RS13410	COG0799	negative regulation of ribosome biogenesis
FLM25_RS13425	COG1466	dna polymerase III delta subunit
FLM25_RS13440	COG2888	peptidyl-tyrosine sulfation
FLM25_RS13455	COG1126	abc transporter atp-binding protein
FLM25_RS13460	COG0765	amino acid transport
FLM25_RS13465	COG0765	amino acid transport
FLM25_RS13480	COG4535	Mg2 and Co2 transporter CorC
FLM25_RS13490	COG1702	phosphate starvation-inducible protein PhoH
FLM25_RS13500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLM25_RS13540	COG0367	asparagine synthase
FLM25_RS13545	COG0647	UMP catabolic process
FLM25_RS13550	COG1846	Transcriptional regulator
FLM25_RS13550	COG1940	carbohydrate kinase activity
FLM25_RS13555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FLM25_RS13595	COG0735	belongs to the Fur family
FLM25_RS13610	COG0596	Alpha beta hydrolase
FLM25_RS13620	COG0033	Phosphoglucomutase
FLM25_RS13630	COG0745	RESPONSE REGULATOR receiver
FLM25_RS13635	COG2205	protein histidine kinase activity
FLM25_RS13665	COG0415	Belongs to the DNA photolyase family
FLM25_RS13680	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FLM25_RS13685	COG1984	allophanate hydrolase subunit 2
FLM25_RS13720	COG2009	succinate dehydrogenase
FLM25_RS13725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FLM25_RS13730	COG1053	succinate dehydrogenase
FLM25_RS13735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FLM25_RS13740	COG0567	Dehydrogenase, E1 component
FLM25_RS13745	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLM25_RS13755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FLM25_RS13760	COG1271	oxidase subunit
FLM25_RS13765	COG1294	oxidase, subunit
FLM25_RS13770	COG4890	Cyd operon protein YbgT
FLM25_RS13775	COG3790	cyd operon protein YbgE
FLM25_RS13780	COG0824	Thioesterase
FLM25_RS13785	COG0811	peptide transport
FLM25_RS13790	COG0848	biopolymer transport protein
FLM25_RS13795	COG3064	Membrane
FLM25_RS13805	COG2885	chlorophyll binding
FLM25_RS13810	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FLM25_RS13855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FLM25_RS13860	COG3201	nicotinamide mononucleotide transporter
FLM25_RS13875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FLM25_RS13885	COG2017	converts alpha-aldose to the beta-anomer
FLM25_RS13895	COG1085	galactose-1-phosphate uridylyltransferase
FLM25_RS13905	COG1119	ATPase activity
FLM25_RS13910	COG3585	molybdate ion transport
FLM25_RS13910	COG2005	Transcriptional regulator
FLM25_RS13920	COG0725	ABC transporter, periplasmic molybdate-binding protein
FLM25_RS13925	COG4149	molybdate abc transporter
FLM25_RS13930	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FLM25_RS13935	COG0561	phosphatase activity
FLM25_RS13960	COG2200	EAL domain
FLM25_RS13965	COG0789	Transcriptional regulator
FLM25_RS14000	COG4677	pectinesterase activity
FLM25_RS14040	COG1881	PFAM PEBP family protein
FLM25_RS14045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FLM25_RS14060	COG2226	methyltransferase
FLM25_RS14085	COG0642	Histidine kinase
FLM25_RS14090	COG0745	RESPONSE REGULATOR receiver
FLM25_RS14110	COG0521	Mo-molybdopterin cofactor biosynthetic process
FLM25_RS14120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FLM25_RS14125	COG0314	molybdopterin synthase activity
FLM25_RS14130	COG0670	Belongs to the BI1 family
FLM25_RS14135	COG0392	lysyltransferase activity
FLM25_RS14140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLM25_RS14145	COG3568	Endonuclease Exonuclease Phosphatase
FLM25_RS14155	COG0842	Transport permease protein
FLM25_RS14160	COG0842	Transport permease protein
FLM25_RS14165	COG1131	(ABC) transporter
FLM25_RS14170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLM25_RS14175	COG1309	transcriptional regulator
FLM25_RS14180	COG0583	DNA-binding transcription factor activity
FLM25_RS14190	COG2271	Major facilitator Superfamily
FLM25_RS14195	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS14200	COG3959	Transketolase, thiamine diphosphate binding domain
FLM25_RS14205	COG3958	Transketolase
FLM25_RS14210	COG0513	Belongs to the DEAD box helicase family
FLM25_RS14215	COG1199	ATP-dependent helicase activity
FLM25_RS14220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FLM25_RS14230	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FLM25_RS14240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FLM25_RS14250	COG0668	transmembrane transport
FLM25_RS14255	COG1126	abc transporter atp-binding protein
FLM25_RS14260	COG0765	amino acid transport
FLM25_RS14265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM25_RS14280	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FLM25_RS14285	COG2194	sulfuric ester hydrolase activity
FLM25_RS14295	COG1321	iron dependent repressor
FLM25_RS14300	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FLM25_RS14305	COG2723	6-phospho-beta-galactosidase activity
FLM25_RS14310	COG2188	Transcriptional regulator
FLM25_RS14315	COG1376	ErfK ybiS ycfS ynhG family protein
FLM25_RS14320	COG2365	Tyrosine phosphatase family
FLM25_RS14325	COG0488	(ABC) transporter
FLM25_RS14335	COG2271	Major facilitator Superfamily
FLM25_RS14340	COG1609	Transcriptional regulator
FLM25_RS14350	COG0561	phosphatase activity
FLM25_RS14355	COG1882	Formate acetyltransferase
FLM25_RS14360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FLM25_RS14365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FLM25_RS14370	COG0303	'Molybdopterin
FLM25_RS14385	COG0747	negative chemotaxis
FLM25_RS14405	COG2223	nitrite transmembrane transporter activity
FLM25_RS14415	COG2133	pyrroloquinoline quinone binding
FLM25_RS14420	COG0625	glutathione transferase activity
FLM25_RS14435	COG1686	Belongs to the peptidase S11 family
FLM25_RS14440	COG1349	DNA-binding transcription factor activity
FLM25_RS14445	COG0671	phosphoesterase, PA-phosphatase related
FLM25_RS14450	COG2814	Major facilitator Superfamily
FLM25_RS14455	COG0561	phosphatase activity
FLM25_RS14460	COG0738	Major facilitator superfamily
FLM25_RS14465	COG3226	Transcriptional regulator
FLM25_RS14470	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FLM25_RS14475	COG3344	reverse transcriptase
FLM25_RS14515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FLM25_RS14550	COG4695	Portal protein
FLM25_RS14745	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FLM25_RS14750	COG3842	ATPase activity
FLM25_RS14755	COG1176	ABC-type spermidine putrescine transport system, permease component I
FLM25_RS14760	COG1177	transmembrane transport
FLM25_RS14775	COG0745	RESPONSE REGULATOR receiver
FLM25_RS14780	COG5002	protein histidine kinase activity
FLM25_RS14785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM25_RS14790	COG4160	amino acid transport
FLM25_RS14795	COG4215	(ABC) transporter
FLM25_RS14800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM25_RS14805	COG1126	abc transporter atp-binding protein
FLM25_RS14815	COG4251	negative regulation of phosphorylation
FLM25_RS14815	COG5001	Diguanylate cyclase
FLM25_RS14815	COG2203	Gaf domain
FLM25_RS14815	COG3706	GGDEF domain
FLM25_RS14820	COG3023	N-Acetylmuramoyl-L-alanine amidase
FLM25_RS14825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLM25_RS14830	COG0702	epimerase
FLM25_RS14835	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FLM25_RS14840	COG0028	Belongs to the TPP enzyme family
FLM25_RS14850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FLM25_RS14860	COG2431	L-lysine efflux transmembrane transporter activity
FLM25_RS14870	COG3593	DNA synthesis involved in DNA repair
FLM25_RS14875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLM25_RS14885	COG1278	Cold shock
FLM25_RS14895	COG0542	response to heat
FLM25_RS14910	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FLM25_RS14915	COG4988	ABC transporter
FLM25_RS14920	COG0492	ferredoxin-NADP+ reductase activity
FLM25_RS14930	COG1674	ftsk spoiiie
FLM25_RS14930	COG1178	ABC-type Fe3 transport system permease component
FLM25_RS14940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FLM25_RS14950	COG0243	molybdopterin cofactor binding
FLM25_RS14955	COG0437	4 iron, 4 sulfur cluster binding
FLM25_RS14960	COG3302	dmso reductase anchor subunit
FLM25_RS14965	COG0477	Major facilitator Superfamily
FLM25_RS14970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FLM25_RS14975	COG1882	Formate acetyltransferase
FLM25_RS14980	COG2116	formate transmembrane transporter activity
FLM25_RS14985	COG1944	ATP diphosphatase activity
FLM25_RS14990	COG2323	membrane
FLM25_RS15010	COG0539	negative regulation of cytoplasmic translation
FLM25_RS15020	COG2333	competence protein COMEC
FLM25_RS15020	COG0658	competence protein
FLM25_RS15035	COG3214	Protein conserved in bacteria
FLM25_RS15050	COG3173	Aminoglycoside phosphotransferase
FLM25_RS15055	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FLM25_RS15060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FLM25_RS15070	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FLM25_RS15080	COG2989	Protein conserved in bacteria
FLM25_RS15085	COG3108	Peptidase M15
FLM25_RS15090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLM25_RS15095	COG1448	Aminotransferase
FLM25_RS15120	COG0814	amino acid
FLM25_RS15130	COG1473	amidohydrolase
FLM25_RS15140	COG0308	aminopeptidase N
FLM25_RS15150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLM25_RS15155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLM25_RS15160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLM25_RS15165	COG0431	NADPH-dependent FMN reductase
FLM25_RS15180	COG3217	Mosc domain protein beta barrel domain protein
FLM25_RS15180	COG0633	Ferredoxin
FLM25_RS15190	COG0488	(ABC) transporter
FLM25_RS15195	COG2995	paraquat-inducible protein a
FLM25_RS15200	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FLM25_RS15200	COG3008	intermembrane lipid transfer
FLM25_RS15205	COG3009	Protein conserved in bacteria
FLM25_RS15210	COG3130	regulation of translation
FLM25_RS15220	COG1067	ATP-dependent peptidase activity
FLM25_RS15240	COG3070	regulator of competence-specific genes
FLM25_RS15245	COG1289	transmembrane transporter activity
FLM25_RS15250	COG3304	Inner membrane component domain
FLM25_RS15255	COG0210	DNA helicase
FLM25_RS15265	COG1832	CoA-binding protein
FLM25_RS15280	COG1881	PFAM PEBP family protein
FLM25_RS15285	COG2207	Transcriptional regulator
FLM25_RS15300	COG0670	Belongs to the BI1 family
FLM25_RS15325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FLM25_RS15330	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS15335	COG4638	Rieske (2fe-2S)
FLM25_RS15340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FLM25_RS15345	COG0473	3-isopropylmalate dehydrogenase activity
FLM25_RS15350	COG0583	DNA-binding transcription factor activity
FLM25_RS15355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLM25_RS15360	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS15365	COG1917	Cupin 2, conserved barrel domain protein
FLM25_RS15365	COG1396	sequence-specific DNA binding
FLM25_RS15370	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FLM25_RS15375	COG0174	glutamine synthetase
FLM25_RS15380	COG0531	amino acid
FLM25_RS15395	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS15425	COG3729	General stress protein
FLM25_RS15435	COG2233	PERMEase
FLM25_RS15470	COG1309	transcriptional regulator
FLM25_RS15485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLM25_RS15495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLM25_RS15515	COG1702	phosphate starvation-inducible protein PhoH
FLM25_RS15520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FLM25_RS15530	COG1335	isochorismatase
FLM25_RS15540	COG0583	DNA-binding transcription factor activity
FLM25_RS15570	COG3381	protein complex oligomerization
FLM25_RS15605	COG5645	(Lipo)protein
FLM25_RS15620	COG1560	Kdo2-lipid A biosynthetic process
FLM25_RS15670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLM25_RS15690	COG2814	Major facilitator Superfamily
FLM25_RS15695	COG0583	DNA-binding transcription factor activity
FLM25_RS15700	COG1530	ribonuclease E activity
FLM25_RS15720	COG1399	metal-binding, possibly nucleic acid-binding protein
FLM25_RS15740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FLM25_RS15755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FLM25_RS15760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLM25_RS15765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FLM25_RS15775	COG0470	DNA polymerase III
FLM25_RS15780	COG0084	hydrolase, TatD family'
FLM25_RS15790	COG0537	adenosine 5'-monophosphoramidase activity
FLM25_RS15795	COG5633	Lipoprotein
FLM25_RS15820	COG1252	NADH dehydrogenase
FLM25_RS15825	COG3134	Outer membrane lipoprotein
FLM25_RS15840	COG1309	transcriptional regulator
FLM25_RS15855	COG1388	LysM domain
FLM25_RS15855	COG1376	ErfK ybiS ycfS ynhG family protein
FLM25_RS15860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FLM25_RS15870	COG4591	ABC-type transport system involved in lipoprotein release permease component
FLM25_RS15880	COG4591	ABC-type transport system involved in lipoprotein release permease component
FLM25_RS15890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FLM25_RS15900	COG0318	PFAM AMP-dependent synthetase and ligase
FLM25_RS15915	COG1177	transmembrane transport
FLM25_RS15935	COG2850	peptidyl-arginine hydroxylation
FLM25_RS15940	COG2205	protein histidine kinase activity
FLM25_RS15960	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FLM25_RS15980	COG1187	pseudouridine synthase activity
FLM25_RS15985	COG0538	isocitrate dehydrogenase activity
FLM25_RS15990	COG0640	Transcriptional regulator
FLM25_RS16010	COG3813	Protein conserved in bacteria
FLM25_RS16015	COG1063	alcohol dehydrogenase
FLM25_RS16020	COG3729	General stress protein
FLM25_RS16025	COG3685	Protein conserved in bacteria
FLM25_RS16030	COG3685	Protein conserved in bacteria
FLM25_RS16035	COG3546	catalase activity
FLM25_RS16040	COG1271	oxidase subunit
FLM25_RS16045	COG1294	oxidase, subunit
FLM25_RS16075	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FLM25_RS16080	COG0583	DNA-binding transcription factor activity
FLM25_RS16085	COG3706	GGDEF domain
FLM25_RS16090	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FLM25_RS16100	COG1560	Kdo2-lipid A biosynthetic process
FLM25_RS16110	COG3182	Iron-regulated membrane protein
FLM25_RS16130	COG2203	Gaf domain
FLM25_RS16130	COG2199	diguanylate cyclase activity
FLM25_RS16135	COG3042	response to heat
FLM25_RS16140	COG3189	MarR family transcriptional regulator
FLM25_RS16145	COG1683	Conserved Protein
FLM25_RS16150	COG0504	CTP synthase activity
FLM25_RS16155	COG2807	transmembrane transport
FLM25_RS16160	COG2207	Transcriptional regulator
FLM25_RS16170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FLM25_RS16175	COG0859	PFAM glycosyl transferase family 9
FLM25_RS16185	COG3344	reverse transcriptase
FLM25_RS16190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FLM25_RS16195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLM25_RS16200	COG0583	DNA-binding transcription factor activity
FLM25_RS16205	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS16230	COG0386	Belongs to the glutathione peroxidase family
FLM25_RS16245	COG2766	serine protein kinase
FLM25_RS16250	COG3713	MltA-interacting MipA family protein
FLM25_RS16255	COG0656	L-ascorbic acid biosynthetic process
FLM25_RS16275	COG3139	Protein of unknown function (DUF1315)
FLM25_RS16290	COG1063	alcohol dehydrogenase
FLM25_RS16295	COG2271	Major facilitator Superfamily
FLM25_RS16300	COG1063	alcohol dehydrogenase
FLM25_RS16305	COG0191	fructose-bisphosphate aldolase activity
FLM25_RS16310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLM25_RS16315	COG0667	Aldo Keto reductase
FLM25_RS16320	COG1349	DNA-binding transcription factor activity
FLM25_RS16325	COG2814	Major facilitator Superfamily
FLM25_RS16330	COG1335	isochorismatase
FLM25_RS16335	COG0252	asparaginase activity
FLM25_RS16340	COG0616	signal peptide processing
FLM25_RS16345	COG0778	Nitroreductase
FLM25_RS16360	COG0709	Synthesizes selenophosphate from selenide and ATP
FLM25_RS16365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLM25_RS16370	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS16370	COG3321	synthase
FLM25_RS16370	COG0604	alcohol dehydrogenase
FLM25_RS16375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FLM25_RS16380	COG0494	nUDIX hydrolase
FLM25_RS16385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FLM25_RS16390	COG2897	thiosulfate sulfurtransferase activity
FLM25_RS16395	COG4136	ATPase activity
FLM25_RS16400	COG4135	transport system, permease component
FLM25_RS16405	COG4134	Bacterial extracellular solute-binding protein
FLM25_RS16410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLM25_RS16415	COG0398	Pfam SNARE associated Golgi protein
FLM25_RS16420	COG0398	Pfam SNARE associated Golgi protein
FLM25_RS16425	COG0708	Exodeoxyribonuclease III
FLM25_RS16435	COG3138	arginine N-succinyltransferase
FLM25_RS16445	COG3724	N-succinylarginine dihydrolase activity
FLM25_RS16455	COG3678	ATP-independent chaperone mediated protein folding
FLM25_RS16460	COG0322	excinuclease ABC activity
FLM25_RS16470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FLM25_RS16475	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLM25_RS16485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLM25_RS16490	COG1447	Phosphotransferase system cellobiose-specific component IIA
FLM25_RS16495	COG1917	Cupin 2, conserved barrel domain protein
FLM25_RS16495	COG2169	Transcriptional regulator
FLM25_RS16500	COG1486	melibiose metabolic process
FLM25_RS16510	COG0753	catalase activity
FLM25_RS16525	COG1988	membrane-bound metal-dependent
FLM25_RS16530	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS16535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FLM25_RS16565	COG0727	PFAM Uncharacterised protein family (UPF0153)
FLM25_RS16570	COG3047	cAMP biosynthetic process
FLM25_RS16580	COG4774	siderophore transport
FLM25_RS16635	COG0135	phosphoribosylanthranilate isomerase activity
FLM25_RS16635	COG0134	indole-3-glycerol-phosphate synthase activity
FLM25_RS16640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FLM25_RS16640	COG0512	Glutamine amidotransferase of anthranilate synthase
FLM25_RS16645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLM25_RS16655	COG0009	L-threonylcarbamoyladenylate synthase
FLM25_RS16665	COG0583	DNA-binding transcription factor activity
FLM25_RS16675	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FLM25_RS16680	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS16690	COG0616	signal peptide processing
FLM25_RS16715	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FLM25_RS16725	COG0671	phosphoesterase, PA-phosphatase related
FLM25_RS16730	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FLM25_RS16735	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FLM25_RS16745	COG0023	Translation Initiation Factor
FLM25_RS16755	COG1349	DNA-binding transcription factor activity
FLM25_RS16770	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLM25_RS16770	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLM25_RS16775	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FLM25_RS16785	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FLM25_RS16800	COG4171	peptide transport system, permease
FLM25_RS16815	COG0702	epimerase
FLM25_RS16830	COG1473	amidohydrolase
FLM25_RS16840	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FLM25_RS16845	COG1842	Phage shock protein A
FLM25_RS16855	COG1983	PspC domain protein
FLM25_RS16865	COG3106	COG3106 Predicted ATPase
FLM25_RS16875	COG0583	DNA-binding transcription factor activity
FLM25_RS16880	COG1486	melibiose metabolic process
FLM25_RS16890	COG3180	Ammonia monooxygenase
FLM25_RS16895	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FLM25_RS16900	COG4948	Mandelate Racemase Muconate Lactonizing
FLM25_RS16905	COG2866	Carboxypeptidase
FLM25_RS16915	COG4166	transmembrane transport
FLM25_RS16945	COG0656	L-ascorbic acid biosynthetic process
FLM25_RS16960	COG0583	DNA-binding transcription factor activity
FLM25_RS16965	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS16970	COG1078	dGTPase activity
FLM25_RS16975	COG0693	protein deglycase activity
FLM25_RS16980	COG0582	viral genome integration into host DNA
FLM25_RS17085	COG0484	heat shock protein binding
FLM25_RS17095	COG3772	lysozyme
FLM25_RS17115	COG1783	phage Terminase large subunit
FLM25_RS17120	COG3567	Phage-associated protein, HI1409 family
FLM25_RS17200	COG0741	lytic transglycosylase activity
FLM25_RS17200	COG0739	heme binding
FLM25_RS17200	COG1196	nuclear chromosome segregation
FLM25_RS17315	COG2885	chlorophyll binding
FLM25_RS17410	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS17415	COG1309	transcriptional regulator
FLM25_RS17420	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS17440	COG0583	DNA-binding transcription factor activity
FLM25_RS17470	COG0604	alcohol dehydrogenase
FLM25_RS17475	COG0436	Aminotransferase
FLM25_RS17490	COG2011	ABC-type metal ion transport system permease component
FLM25_RS17495	COG1448	Aminotransferase
FLM25_RS17505	COG1522	sequence-specific DNA binding
FLM25_RS17510	COG1113	amino acid transport
FLM25_RS17525	COG0673	inositol 2-dehydrogenase activity
FLM25_RS17530	COG1349	DNA-binding transcription factor activity
FLM25_RS17540	COG0513	Belongs to the DEAD box helicase family
FLM25_RS17550	COG0589	response to stress
FLM25_RS17560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FLM25_RS17570	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FLM25_RS17570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FLM25_RS17570	COG0674	pyruvate-flavodoxin oxidoreductase activity
FLM25_RS17570	COG1013	pyruvate-flavodoxin oxidoreductase activity
FLM25_RS17575	COG3042	response to heat
FLM25_RS17580	COG3187	Heat shock protein
FLM25_RS17585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLM25_RS17590	COG0586	Pfam SNARE associated Golgi protein
FLM25_RS17595	COG2911	Protein conserved in bacteria
FLM25_RS17605	COG3784	Protein of unknown function (DUF1318)
FLM25_RS17610	COG2207	Transcriptional regulator
FLM25_RS17615	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS17640	COG3396	Phenylacetate-CoA oxygenase
FLM25_RS17645	COG3460	Phenylacetate-CoA oxygenase
FLM25_RS17650	COG3396	Phenylacetate-CoA oxygenase
FLM25_RS17655	COG2151	metal-sulfur cluster biosynthetic enzyme
FLM25_RS17660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FLM25_RS17665	COG1024	Enoyl-CoA hydratase
FLM25_RS17670	COG1024	Enoyl-CoA hydratase
FLM25_RS17675	COG1250	3-hydroxyacyl-CoA dehydrogenase
FLM25_RS17680	COG2050	protein possibly involved in aromatic compounds catabolism
FLM25_RS17685	COG0183	Belongs to the thiolase family
FLM25_RS17690	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FLM25_RS17695	COG3327	negative regulation of DNA-templated transcription, initiation
FLM25_RS17700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FLM25_RS17715	COG1643	Atp-dependent helicase
FLM25_RS17720	COG4122	O-methyltransferase activity
FLM25_RS17745	COG0583	DNA-binding transcription factor activity
FLM25_RS17750	COG0667	Aldo Keto reductase
FLM25_RS17755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FLM25_RS17765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLM25_RS17770	COG3138	arginine N-succinyltransferase
FLM25_RS17775	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS17780	COG3724	N-succinylarginine dihydrolase activity
FLM25_RS17785	COG2988	succinylglutamate desuccinylase activity
FLM25_RS17790	COG1113	amino acid transport
FLM25_RS17795	COG0477	Major facilitator Superfamily
FLM25_RS17800	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FLM25_RS17810	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS17815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FLM25_RS17820	COG0401	homolog of Blt101
FLM25_RS17825	COG5562	phage envelope protein
FLM25_RS17830	COG0425	Belongs to the sulfur carrier protein TusA family
FLM25_RS17835	COG2391	methyltransferase activity
FLM25_RS17860	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FLM25_RS17865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLM25_RS17865	COG1263	PTS System
FLM25_RS17870	COG1609	Transcriptional regulator
FLM25_RS17875	COG5339	Protein conserved in bacteria
FLM25_RS17880	COG1482	cell wall glycoprotein biosynthetic process
FLM25_RS17885	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FLM25_RS17885	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FLM25_RS17890	COG0114	fumarate hydratase activity
FLM25_RS17900	COG2205	protein histidine kinase activity
FLM25_RS17910	COG0745	RESPONSE REGULATOR receiver
FLM25_RS17915	COG3136	membrane protein required for alginate biosynthesis
FLM25_RS17925	COG0531	amino acid
FLM25_RS17940	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FLM25_RS17945	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FLM25_RS17960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FLM25_RS17975	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FLM25_RS17990	COG0583	DNA-binding transcription factor activity
FLM25_RS17995	COG2840	Smr protein MutS2
FLM25_RS18000	COG1414	Transcriptional regulator
FLM25_RS18010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FLM25_RS18015	COG0183	Belongs to the thiolase family
FLM25_RS18025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FLM25_RS18030	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLM25_RS18040	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FLM25_RS18040	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FLM25_RS18060	COG4565	transcriptional regulatory protein
FLM25_RS18065	COG3290	protein histidine kinase activity
FLM25_RS18090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FLM25_RS18100	COG0679	Auxin Efflux Carrier
FLM25_RS18130	COG0628	permease
FLM25_RS18150	COG3591	Belongs to the peptidase S1B family
FLM25_RS18160	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FLM25_RS18165	COG2814	Major facilitator Superfamily
FLM25_RS18170	COG0583	DNA-binding transcription factor activity
FLM25_RS18175	COG1940	carbohydrate kinase activity
FLM25_RS18180	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FLM25_RS18195	COG3302	dmso reductase anchor subunit
FLM25_RS18200	COG0437	4 iron, 4 sulfur cluster binding
FLM25_RS18205	COG0243	molybdopterin cofactor binding
FLM25_RS18220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLM25_RS18235	COG2271	Major facilitator Superfamily
FLM25_RS18240	COG0246	Mannitol dehydrogenase
FLM25_RS18245	COG0589	response to stress
FLM25_RS18250	COG1802	Transcriptional regulator
FLM25_RS18255	COG4221	oxidoreductase activity
FLM25_RS18270	COG2207	Transcriptional regulator
FLM25_RS18275	COG2135	peptidase activity
FLM25_RS18310	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS18315	COG2731	YhcH YjgK YiaL family protein
FLM25_RS18330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLM25_RS18340	COG3395	kinase activity
FLM25_RS18345	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FLM25_RS18350	COG1349	DNA-binding transcription factor activity
FLM25_RS18355	COG0039	L-malate dehydrogenase activity
FLM25_RS18365	COG0583	DNA-binding transcription factor activity
FLM25_RS18370	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS18385	COG2199	diguanylate cyclase activity
FLM25_RS18455	COG0477	Major facilitator Superfamily
FLM25_RS18465	COG2070	2-Nitropropane dioxygenase
FLM25_RS18470	COG2011	ABC-type metal ion transport system permease component
FLM25_RS18490	COG4628	conserved protein (DUF2132)
FLM25_RS18505	COG2207	Transcriptional regulator
FLM25_RS18535	COG2233	PERMEase
FLM25_RS18540	COG3648	Uricase
FLM25_RS18540	COG3195	allantoin biosynthetic process
FLM25_RS18545	COG2351	hydroxyisourate hydrolase activity
FLM25_RS18550	COG1396	sequence-specific DNA binding
FLM25_RS18555	COG3550	peptidyl-serine autophosphorylation
FLM25_RS18570	COG3188	usher protein
FLM25_RS18605	COG3300	MHYT domain
FLM25_RS18605	COG5001	Diguanylate cyclase
FLM25_RS18610	COG2819	hydrolase of the alpha beta superfamily
FLM25_RS18625	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS18625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS18630	COG2814	Major facilitator Superfamily
FLM25_RS18640	COG1263	PTS System
FLM25_RS18640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLM25_RS18645	COG2186	Transcriptional regulator
FLM25_RS18665	COG3835	regulator
FLM25_RS18670	COG1929	Belongs to the glycerate kinase type-1 family
FLM25_RS18715	COG0738	Major facilitator superfamily
FLM25_RS18720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLM25_RS18725	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FLM25_RS18730	COG1349	DNA-binding transcription factor activity
FLM25_RS18745	COG1349	DNA-binding transcription factor activity
FLM25_RS18760	COG4977	sequence-specific DNA binding
FLM25_RS18785	COG0667	Aldo Keto reductase
FLM25_RS18790	COG3386	PFAM SMP-30 Gluconolaconase
FLM25_RS18795	COG0667	Aldo Keto reductase
FLM25_RS18800	COG0667	Aldo Keto reductase
FLM25_RS18810	COG0456	acetyltransferase
FLM25_RS18810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FLM25_RS18835	COG1652	LysM domain
FLM25_RS18865	COG1609	Transcriptional regulator
FLM25_RS18875	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS18890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLM25_RS18900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLM25_RS18905	COG0583	DNA-binding transcription factor activity
FLM25_RS18910	COG0583	DNA-binding transcription factor activity
FLM25_RS18925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLM25_RS18925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLM25_RS18925	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FLM25_RS18930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLM25_RS18945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FLM25_RS18950	COG3037	sugar-specific permease SgaT UlaA
FLM25_RS18960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS18965	COG1609	Transcriptional regulator
FLM25_RS18975	COG2223	nitrite transmembrane transporter activity
FLM25_RS19005	COG0477	Major facilitator Superfamily
FLM25_RS19010	COG4529	Protein conserved in bacteria
FLM25_RS19015	COG1902	pentaerythritol trinitrate reductase activity
FLM25_RS19025	COG0583	DNA-binding transcription factor activity
FLM25_RS19030	COG2070	2-Nitropropane dioxygenase
FLM25_RS19040	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FLM25_RS19095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FLM25_RS19120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FLM25_RS19135	COG0583	DNA-binding transcription factor activity
FLM25_RS19150	COG2207	Transcriptional regulator
FLM25_RS19165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FLM25_RS19180	COG0406	alpha-ribazole phosphatase activity
FLM25_RS19215	COG1953	Uracil, thiamine, allantoin
FLM25_RS19220	COG0402	S-adenosylhomocysteine deaminase activity
FLM25_RS19225	COG3706	GGDEF domain
FLM25_RS19240	COG0673	inositol 2-dehydrogenase activity
FLM25_RS19255	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FLM25_RS19260	COG1116	anion transmembrane transporter activity
FLM25_RS19265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLM25_RS19270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLM25_RS19275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FLM25_RS19280	COG0076	glutamate decarboxylase activity
FLM25_RS19295	COG2205	protein histidine kinase activity
FLM25_RS19300	COG0745	RESPONSE REGULATOR receiver
FLM25_RS19305	COG0596	Alpha beta hydrolase
FLM25_RS19345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FLM25_RS19345	COG0519	Catalyzes the synthesis of GMP from XMP
FLM25_RS19365	COG0583	DNA-binding transcription factor activity
FLM25_RS19375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FLM25_RS19380	COG1285	pathogenesis
FLM25_RS19385	COG2814	Major facilitator Superfamily
FLM25_RS19390	COG0583	DNA-binding transcription factor activity
FLM25_RS19395	COG0243	molybdopterin cofactor binding
FLM25_RS19400	COG3781	membrane
FLM25_RS19425	COG1764	response to oxidative stress
FLM25_RS19435	COG3111	PFAM Bacterial OB fold (BOF) protein
FLM25_RS19450	COG2323	membrane
FLM25_RS19460	COG0366	Alpha amylase catalytic
FLM25_RS19470	COG3685	Protein conserved in bacteria
FLM25_RS19480	COG3729	General stress protein
FLM25_RS19485	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS19525	COG0488	(ABC) transporter
FLM25_RS19540	COG1064	alcohol dehydrogenase
FLM25_RS19545	COG0747	negative chemotaxis
FLM25_RS19565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLM25_RS19575	COG2814	Major facilitator Superfamily
FLM25_RS19585	COG2326	polyphosphate kinase activity
FLM25_RS19600	COG2864	formate dehydrogenase
FLM25_RS19605	COG0437	4 iron, 4 sulfur cluster binding
FLM25_RS19630	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FLM25_RS19640	COG3485	protocatechuate 3,4-dioxygenase
FLM25_RS19645	COG4829	muconolactone delta-isomerase
FLM25_RS19650	COG4948	Mandelate Racemase Muconate Lactonizing
FLM25_RS19655	COG1414	Transcriptional regulator
FLM25_RS19675	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FLM25_RS19680	COG1140	nitrate reductase beta subunit
FLM25_RS19685	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FLM25_RS19690	COG2181	nitrate reductase activity
FLM25_RS19695	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FLM25_RS19700	COG1178	ABC-type Fe3 transport system permease component
FLM25_RS19705	COG1840	ABC-type Fe3 transport system, periplasmic component
FLM25_RS19710	COG3842	ATPase activity
FLM25_RS19715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FLM25_RS19730	COG2211	Major facilitator Superfamily
FLM25_RS19745	COG0625	glutathione transferase activity
FLM25_RS19755	COG1126	abc transporter atp-binding protein
FLM25_RS19760	COG0765	amino acid transport
FLM25_RS19775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLM25_RS19780	COG1473	amidohydrolase
FLM25_RS19785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLM25_RS19790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FLM25_RS19815	COG4772	TonB-dependent receptor
FLM25_RS19820	COG1228	amidohydrolase
FLM25_RS19825	COG3691	Protein conserved in bacteria
FLM25_RS19840	COG2130	NADP-dependent
FLM25_RS19850	COG1247	-acetyltransferase
FLM25_RS19855	COG3238	Protein conserved in bacteria
FLM25_RS19865	COG0747	negative chemotaxis
FLM25_RS19870	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS19905	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS19910	COG1177	transmembrane transport
FLM25_RS19915	COG1176	ABC-type spermidine putrescine transport system, permease component I
FLM25_RS19920	COG3842	ATPase activity
FLM25_RS19925	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FLM25_RS19930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLM25_RS19935	COG1271	oxidase subunit
FLM25_RS19940	COG1294	oxidase, subunit
FLM25_RS19960	COG0826	peptidase U32
FLM25_RS19970	COG1396	sequence-specific DNA binding
FLM25_RS19975	COG3135	benzoate transporter
FLM25_RS19980	COG3708	Transcriptional regulator
FLM25_RS19980	COG2207	Transcriptional regulator
FLM25_RS19995	COG0500	methyltransferase
FLM25_RS20000	COG1275	C4-dicarboxylate transporter malic acid transport protein
FLM25_RS20005	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FLM25_RS20010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLM25_RS20025	COG2272	Belongs to the type-B carboxylesterase lipase family
FLM25_RS20030	COG5383	Protein conserved in bacteria
FLM25_RS20035	COG3485	protocatechuate 3,4-dioxygenase
FLM25_RS20040	COG3485	protocatechuate 3,4-dioxygenase
FLM25_RS20045	COG0583	DNA-binding transcription factor activity
FLM25_RS20065	COG3038	cytochrome b561
FLM25_RS20085	COG2814	Major facilitator Superfamily
FLM25_RS20095	COG0673	inositol 2-dehydrogenase activity
FLM25_RS20105	COG2723	6-phospho-beta-galactosidase activity
FLM25_RS20140	COG4659	FMN binding
FLM25_RS20150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FLM25_RS20160	COG0625	glutathione transferase activity
FLM25_RS20165	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FLM25_RS20180	COG3895	Periplasmic Protein
FLM25_RS20195	COG3706	GGDEF domain
FLM25_RS20210	COG1566	PFAM secretion protein HlyD family protein
FLM25_RS20215	COG1289	transmembrane transporter activity
FLM25_RS20220	COG2032	superoxide dismutase activity
FLM25_RS20225	COG4989	oxidoreductase activity
FLM25_RS20230	COG3313	Fe-S protein
FLM25_RS20235	COG1309	transcriptional regulator
FLM25_RS20240	COG1902	pentaerythritol trinitrate reductase activity
FLM25_RS20245	COG0346	lactoylglutathione lyase activity
FLM25_RS20255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FLM25_RS20260	COG0791	NLP P60 protein
FLM25_RS20275	COG2814	Major facilitator Superfamily
FLM25_RS20290	COG0583	DNA-binding transcription factor activity
FLM25_RS20295	COG2814	Major facilitator Superfamily
FLM25_RS20300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FLM25_RS20305	COG0307	riboflavin synthase, alpha
FLM25_RS20360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FLM25_RS20395	COG1349	DNA-binding transcription factor activity
FLM25_RS20400	COG0346	lactoylglutathione lyase activity
FLM25_RS20425	COG0444	Belongs to the ABC transporter superfamily
FLM25_RS20430	COG4608	Belongs to the ABC transporter superfamily
FLM25_RS20485	COG0402	S-adenosylhomocysteine deaminase activity
FLM25_RS20510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLM25_RS20515	COG0277	FAD linked oxidase domain protein
FLM25_RS20540	COG0583	DNA-binding transcription factor activity
FLM25_RS20550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FLM25_RS20560	COG1250	3-hydroxyacyl-CoA dehydrogenase
FLM25_RS20565	COG2610	gluconate transmembrane transporter activity
FLM25_RS20570	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS20600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLM25_RS20630	COG3088	subunit of a heme lyase
FLM25_RS20630	COG4235	cytochrome complex assembly
FLM25_RS20635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLM25_RS20640	COG1138	Cytochrome C-type biogenesis protein
FLM25_RS20655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLM25_RS20660	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLM25_RS20665	COG4133	protoheme IX ABC transporter activity
FLM25_RS20695	COG1175	transmembrane transport
FLM25_RS20705	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FLM25_RS20710	COG3383	formate dehydrogenase (NAD+) activity
FLM25_RS20750	COG1126	abc transporter atp-binding protein
FLM25_RS20755	COG0765	amino acid transport
FLM25_RS20775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLM25_RS20780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLM25_RS20785	COG1120	ATPase activity
FLM25_RS20790	COG4774	siderophore transport
FLM25_RS20795	COG1116	anion transmembrane transporter activity
FLM25_RS20800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLM25_RS20820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLM25_RS20825	COG0583	DNA-binding transcription factor activity
FLM25_RS20845	COG2814	Major facilitator Superfamily
FLM25_RS20880	COG1414	Transcriptional regulator
FLM25_RS20905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FLM25_RS20910	COG2271	Major facilitator Superfamily
FLM25_RS20920	COG1309	transcriptional regulator
FLM25_RS20950	COG1376	ErfK ybiS ycfS ynhG family protein
FLM25_RS20965	COG0719	Fe-S assembly protein
FLM25_RS20970	COG0396	ATPase activity
FLM25_RS20975	COG0719	Fe-S assembly protein
FLM25_RS20980	COG0316	Belongs to the HesB IscA family
FLM25_RS21000	COG1309	transcriptional regulator
FLM25_RS21005	COG1304	FMN binding
FLM25_RS21030	COG0583	DNA-binding transcription factor activity
FLM25_RS21040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLM25_RS21045	COG1120	ATPase activity
FLM25_RS21070	COG2050	protein possibly involved in aromatic compounds catabolism
FLM25_RS21075	COG0247	lactate metabolic process
FLM25_RS21075	COG0277	FAD linked oxidase domain protein
FLM25_RS21080	COG0628	permease
FLM25_RS21090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FLM25_RS21090	COG0574	Belongs to the PEP-utilizing enzyme family
FLM25_RS21105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FLM25_RS21110	COG4256	Hemin uptake protein
FLM25_RS21120	COG0791	NLP P60 protein
FLM25_RS21130	COG0386	Belongs to the glutathione peroxidase family
FLM25_RS21150	COG0583	DNA-binding transcription factor activity
FLM25_RS21170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLM25_RS21170	COG0072	phenylalanine-tRNA ligase activity
FLM25_RS21210	COG3137	Salt-induced outer membrane protein
FLM25_RS21215	COG1105	Belongs to the carbohydrate kinase PfkB family
FLM25_RS21225	COG3001	Fructosamine kinase
FLM25_RS21235	COG2350	Protein conserved in bacteria
FLM25_RS21245	COG2353	YceI-like domain
FLM25_RS21265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FLM25_RS21275	COG0444	Belongs to the ABC transporter superfamily
FLM25_RS21280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLM25_RS21285	COG0601	transmembrane transport
FLM25_RS21290	COG4166	transmembrane transport
FLM25_RS21295	COG2095	MarC family integral membrane protein
FLM25_RS21305	COG1454	alcohol dehydrogenase
FLM25_RS21305	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS21310	COG1435	thymidine kinase activity
FLM25_RS21320	COG2916	Histone family protein nucleoid-structuring protein H-NS
FLM25_RS21325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FLM25_RS21330	COG0745	RESPONSE REGULATOR receiver
FLM25_RS21335	COG1752	Esterase of the alpha-beta hydrolase superfamily
FLM25_RS21345	COG0788	formyltetrahydrofolate deformylase activity
FLM25_RS21380	COG1522	sequence-specific DNA binding
FLM25_RS21390	COG2181	nitrate reductase activity
FLM25_RS21395	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FLM25_RS21400	COG1140	nitrate reductase beta subunit
FLM25_RS21405	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FLM25_RS21415	COG2223	nitrite transmembrane transporter activity
FLM25_RS21420	COG3850	Histidine kinase
FLM25_RS21425	COG2197	response regulator
FLM25_RS21430	COG4932	domain protein
FLM25_RS21435	COG0243	molybdopterin cofactor binding
FLM25_RS21440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FLM25_RS21440	COG2146	nitrite reductase [NAD(P)H] activity
FLM25_RS21445	COG1116	anion transmembrane transporter activity
FLM25_RS21455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLM25_RS21460	COG3707	response regulator
FLM25_RS21465	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FLM25_RS21475	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FLM25_RS21480	COG4572	Cation transport regulator
FLM25_RS21485	COG0387	Pfam Sodium calcium exchanger
FLM25_RS21505	COG2890	protein-(glutamine-N5) methyltransferase activity
FLM25_RS21535	COG0659	secondary active sulfate transmembrane transporter activity
FLM25_RS21555	COG0012	GTP binding
FLM25_RS21650	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FLM25_RS21730	COG2885	chlorophyll binding
FLM25_RS21750	COG3122	Protein conserved in bacteria
FLM25_RS21765	COG0583	DNA-binding transcription factor activity
FLM25_RS21795	COG0583	DNA-binding transcription factor activity
FLM25_RS21830	COG1882	Formate acetyltransferase
FLM25_RS21845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FLM25_RS21850	COG0583	DNA-binding transcription factor activity
FLM25_RS21890	COG2308	Evidence 4 Homologs of previously reported genes of
FLM25_RS21900	COG4774	siderophore transport
FLM25_RS21910	COG1619	proteins homologs of microcin C7 resistance protein MccF
FLM25_RS21935	COG2719	SpoVR family
FLM25_RS21965	COG0179	Fumarylacetoacetate (FAA) hydrolase
FLM25_RS21980	COG2894	cell division
FLM25_RS21990	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FLM25_RS22000	COG3065	identical protein binding
FLM25_RS22010	COG1199	ATP-dependent helicase activity
FLM25_RS22015	COG0251	oxidation-reduction process
FLM25_RS22035	COG1760	l-serine dehydratase
FLM25_RS22040	COG2200	EAL domain
FLM25_RS22045	COG1253	flavin adenine dinucleotide binding
FLM25_RS22050	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS22050	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLM25_RS22055	COG3715	PTS system
FLM25_RS22060	COG3716	PTS system mannose fructose sorbose family IID component
FLM25_RS22075	COG2226	methyltransferase
FLM25_RS22080	COG0768	penicillin binding
FLM25_RS22110	COG1414	Transcriptional regulator
FLM25_RS22115	COG2814	Major facilitator Superfamily
FLM25_RS22135	COG1956	GAF domain-containing protein
FLM25_RS22140	COG2995	paraquat-inducible protein a
FLM25_RS22145	COG3008	intermembrane lipid transfer
FLM25_RS22170	COG2990	Protein conserved in bacteria
FLM25_RS22185	COG1276	copper resistance
FLM25_RS22190	COG2372	response to copper ion
FLM25_RS22200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FLM25_RS22205	COG1770	oligopeptidase
FLM25_RS22215	COG3141	response to X-ray
FLM25_RS22225	COG0800	Aldolase
FLM25_RS22230	COG0129	dihydroxy-acid dehydratase activity
FLM25_RS22235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FLM25_RS22245	COG1737	Transcriptional regulator
FLM25_RS22255	COG1560	Kdo2-lipid A biosynthetic process
FLM25_RS22260	COG0739	heme binding
FLM25_RS22265	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FLM25_RS22275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLM25_RS22300	COG0494	nUDIX hydrolase
FLM25_RS22310	COG1335	isochorismatase
FLM25_RS22315	COG1801	Protein of unknown function DUF72
FLM25_RS22320	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FLM25_RS22340	COG3102	Protein conserved in bacteria
FLM25_RS22350	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FLM25_RS22375	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLM25_RS22385	COG1879	ABC-type sugar transport system periplasmic component
FLM25_RS22400	COG1528	Iron-storage protein
FLM25_RS22410	COG2211	Major facilitator Superfamily
FLM25_RS22420	COG0477	Major facilitator Superfamily
FLM25_RS22435	COG1528	Iron-storage protein
FLM25_RS22445	COG0814	amino acid
FLM25_RS22450	COG3012	SEC-C Motif Domain Protein
FLM25_RS22450	COG3318	Belongs to the UPF0149 family
FLM25_RS22485	COG2197	response regulator
FLM25_RS22495	COG2197	response regulator
FLM25_RS22520	COG0366	Alpha amylase catalytic
FLM25_RS22550	COG2354	Protein conserved in bacteria
FLM25_RS22555	COG0697	spore germination
FLM25_RS22560	COG3727	T/G mismatch-specific endonuclease activity
FLM25_RS22565	COG0270	DNA (cytosine-5-)-methyltransferase activity
FLM25_RS22570	COG1418	mRNA catabolic process
FLM25_RS22580	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FLM25_RS22600	COG0251	oxidation-reduction process
FLM25_RS22635	COG0025	NhaP-type Na H and K H
FLM25_RS22640	COG1309	transcriptional regulator
FLM25_RS22645	COG0604	alcohol dehydrogenase
FLM25_RS22665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FLM25_RS22690	COG0534	Mate efflux family protein
FLM25_RS22700	COG0582	viral genome integration into host DNA
FLM25_RS22810	COG2916	Histone family protein nucleoid-structuring protein H-NS
FLM25_RS22850	COG3706	GGDEF domain
FLM25_RS22875	COG3615	Tellurite resistance protein tehB
FLM25_RS22885	COG3300	MHYT domain
FLM25_RS22885	COG5001	Diguanylate cyclase
FLM25_RS22895	COG0477	Major facilitator Superfamily
FLM25_RS22900	COG0095	Lipoate-protein ligase
FLM25_RS22905	COG0583	DNA-binding transcription factor activity
FLM25_RS22910	COG1942	4-Oxalocrotonate Tautomerase
FLM25_RS22920	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FLM25_RS22940	COG1289	transmembrane transporter activity
FLM25_RS22950	COG3344	reverse transcriptase
FLM25_RS22960	COG2925	Exonuclease
FLM25_RS22970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FLM25_RS22975	COG0640	Transcriptional regulator
FLM25_RS22980	COG0531	amino acid
FLM25_RS22990	COG0583	DNA-binding transcription factor activity
FLM25_RS22995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLM25_RS23025	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FLM25_RS23050	COG0463	Glycosyl transferase, family 2
FLM25_RS23060	COG1442	glycosyl transferase family 8
FLM25_RS23060	COG1216	Glycosyl transferase, family 2
FLM25_RS23065	COG0438	transferase activity, transferring glycosyl groups
FLM25_RS23120	COG2244	polysaccharide biosynthetic process
FLM25_RS23150	COG1088	dTDP-glucose 4,6-dehydratase activity
FLM25_RS23175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FLM25_RS23215	COG1253	flavin adenine dinucleotide binding
FLM25_RS23220	COG2982	Protein involved in outer membrane biogenesis
FLM25_RS23235	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FLM25_RS23240	COG0443	Heat shock 70 kDa protein
FLM25_RS23245	COG5002	protein histidine kinase activity
FLM25_RS23265	COG1301	dicarboxylic acid transport
FLM25_RS23290	COG2205	protein histidine kinase activity
FLM25_RS23295	COG0745	RESPONSE REGULATOR receiver
FLM25_RS23310	COG4608	Belongs to the ABC transporter superfamily
FLM25_RS23315	COG0444	Belongs to the ABC transporter superfamily
FLM25_RS23325	COG0601	transmembrane transport
FLM25_RS23330	COG0747	negative chemotaxis
FLM25_RS23335	COG4948	Mandelate Racemase Muconate Lactonizing
FLM25_RS23340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FLM25_RS23375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FLM25_RS23385	COG1830	Aldolase
FLM25_RS23390	COG0351	phosphomethylpyrimidine kinase
FLM25_RS23405	COG0583	DNA-binding transcription factor activity
FLM25_RS23415	COG2252	PERMEase
FLM25_RS23420	COG0583	DNA-binding transcription factor activity
FLM25_RS23425	COG5455	response to cobalt ion
FLM25_RS23445	COG4807	Protein conserved in bacteria
FLM25_RS23455	COG3275	phosphorelay sensor kinase activity
FLM25_RS23465	COG1174	glycine betaine transport
FLM25_RS23470	COG1125	glycine betaine transport
FLM25_RS23475	COG1174	glycine betaine transport
FLM25_RS23480	COG1732	Glycine betaine
FLM25_RS23485	COG1472	Belongs to the glycosyl hydrolase 3 family
FLM25_RS23490	COG0277	FAD linked oxidase domain protein
FLM25_RS23500	COG1686	Belongs to the peptidase S11 family
FLM25_RS23510	COG0586	Pfam SNARE associated Golgi protein
FLM25_RS23515	COG1538	Outer membrane efflux protein
FLM25_RS23520	COG2723	6-phospho-beta-galactosidase activity
FLM25_RS23535	COG3659	wide pore channel activity
FLM25_RS23540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLM25_RS23550	COG1346	cytolysis
FLM25_RS23560	COG2949	membrane
FLM25_RS23570	COG1129	ABC transporter
FLM25_RS23585	COG2311	Membrane
FLM25_RS23600	COG4771	TonB-dependent receptor
FLM25_RS23605	COG0833	amino acid
FLM25_RS23610	COG0583	DNA-binding transcription factor activity
FLM25_RS23615	COG2855	membrane
FLM25_RS23625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLM25_RS23625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLM25_RS23625	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FLM25_RS23630	COG1105	Belongs to the carbohydrate kinase PfkB family
FLM25_RS23635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS23635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS23660	COG1312	Catalyzes the dehydration of D-mannonate
FLM25_RS23665	COG0246	Mannitol dehydrogenase
FLM25_RS23670	COG0523	cobalamin synthesis protein
FLM25_RS23675	COG0671	phosphoesterase, PA-phosphatase related
FLM25_RS23680	COG0791	NLP P60 protein
FLM25_RS23685	COG2200	EAL domain
FLM25_RS23690	COG4166	transmembrane transport
FLM25_RS23695	COG4174	ABC transporter (Permease)
FLM25_RS23700	COG4239	(ABC) transporter, permease
FLM25_RS23705	COG4172	Belongs to the ABC transporter superfamily
FLM25_RS23715	COG2814	Major facilitator Superfamily
FLM25_RS23720	COG1187	pseudouridine synthase activity
FLM25_RS23725	COG1061	Type III restriction enzyme res subunit
FLM25_RS23745	COG0494	nUDIX hydrolase
FLM25_RS23750	COG1349	DNA-binding transcription factor activity
FLM25_RS23775	COG0628	permease
FLM25_RS23790	COG0659	secondary active sulfate transmembrane transporter activity
FLM25_RS23795	COG2239	Acts as a magnesium transporter
FLM25_RS23800	COG4615	Cyclic peptide transporter
FLM25_RS23805	COG3145	DNA-N1-methyladenine dioxygenase activity
FLM25_RS23810	COG2169	Transcriptional regulator
FLM25_RS23810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FLM25_RS23830	COG0642	Histidine kinase
FLM25_RS23830	COG2198	Histidine kinase
FLM25_RS23840	COG0784	Response regulator, receiver
FLM25_RS23840	COG2205	protein histidine kinase activity
FLM25_RS23865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FLM25_RS23870	COG0584	glycerophosphoryl diester phosphodiesterase
FLM25_RS23875	COG2271	Major facilitator Superfamily
FLM25_RS23880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FLM25_RS23890	COG0247	lactate metabolic process
FLM25_RS23900	COG2271	Major facilitator Superfamily
FLM25_RS23915	COG1414	Transcriptional regulator
FLM25_RS23930	COG5464	transposase or invertase
FLM25_RS23940	COG0318	PFAM AMP-dependent synthetase and ligase
FLM25_RS23965	COG1169	isochorismate synthase
FLM25_RS23970	COG2153	protein acetylation
FLM25_RS23985	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FLM25_RS23990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FLM25_RS24000	COG0839	Belongs to the complex I subunit 6 family
FLM25_RS24045	COG0583	DNA-binding transcription factor activity
FLM25_RS24050	COG0436	Aminotransferase
FLM25_RS24060	COG0471	metal ion transport
FLM25_RS24060	COG0490	domain, Protein
FLM25_RS24065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FLM25_RS24085	COG0857	belongs to the CobB CobQ family
FLM25_RS24085	COG0280	phosphate acetyltransferase
FLM25_RS24090	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FLM25_RS24095	COG0622	Phosphoesterase
FLM25_RS24100	COG0625	glutathione transferase activity
FLM25_RS24105	COG0625	glutathione transferase activity
FLM25_RS24110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FLM25_RS24115	COG1090	epimerase
FLM25_RS24130	COG4598	ABC transporter
FLM25_RS24135	COG4160	amino acid transport
FLM25_RS24160	COG0163	prenyltransferase activity
FLM25_RS24165	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FLM25_RS24170	COG1286	toxin biosynthetic process
FLM25_RS24175	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FLM25_RS24180	COG0285	dihydrofolate synthase activity
FLM25_RS24190	COG0586	Pfam SNARE associated Golgi protein
FLM25_RS24200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FLM25_RS24220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FLM25_RS24235	COG3101	peptidyl-lysine hydroxylation
FLM25_RS24240	COG0730	response to heat
FLM25_RS24265	COG2062	phosphohistidine phosphatase, SixA
FLM25_RS24280	COG3691	Protein conserved in bacteria
FLM25_RS24290	COG2853	Lipoprotein
FLM25_RS24295	COG2116	formate transmembrane transporter activity
FLM25_RS24315	COG0583	DNA-binding transcription factor activity
FLM25_RS24320	COG0590	tRNA wobble adenosine to inosine editing
FLM25_RS24325	COG2807	transmembrane transport
FLM25_RS24335	COG0436	Aminotransferase
FLM25_RS24350	COG3275	phosphorelay sensor kinase activity
FLM25_RS24355	COG3279	Response regulator of the LytR AlgR family
FLM25_RS24370	COG3961	Belongs to the TPP enzyme family
FLM25_RS24375	COG0667	Aldo Keto reductase
FLM25_RS24390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLM25_RS24395	COG2199	diguanylate cyclase activity
FLM25_RS24395	COG2200	EAL domain
FLM25_RS24410	COG3415	Transposase
FLM25_RS24415	COG3415	Transposase
FLM25_RS24445	COG0583	DNA-binding transcription factor activity
FLM25_RS24450	COG0385	Bile acid
FLM25_RS24455	COG3530	Putative quorum-sensing-regulated virulence factor
FLM25_RS24475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLM25_RS24510	COG4319	ketosteroid isomerase
FLM25_RS24520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FLM25_RS24525	COG4208	sulfate ABC transporter
FLM25_RS24530	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FLM25_RS24535	COG4150	thiosulfate binding
FLM25_RS24545	COG2837	iron assimilation
FLM25_RS24565	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLM25_RS24655	COG4810	utilization protein
FLM25_RS24665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FLM25_RS24670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FLM25_RS24675	COG5342	invasion associated locus B
FLM25_RS24685	COG0493	'glutamate synthase
FLM25_RS24685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FLM25_RS24690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLM25_RS24700	COG1393	Belongs to the ArsC family
FLM25_RS24715	COG0400	carboxylic ester hydrolase activity
FLM25_RS24720	COG1444	tRNA N-acetyltransferase activity
FLM25_RS24725	COG2321	neutral zinc metallopeptidase
FLM25_RS24735	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FLM25_RS24745	COG2716	regulation of RNA biosynthetic process
FLM25_RS24750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FLM25_RS24755	COG0628	permease
FLM25_RS24765	COG4783	chaperone-mediated protein folding
FLM25_RS24770	COG1393	Belongs to the ArsC family
FLM25_RS24785	COG2233	PERMEase
FLM25_RS24795	COG2723	6-phospho-beta-galactosidase activity
FLM25_RS24810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FLM25_RS24825	COG2200	EAL domain
FLM25_RS24845	COG0641	radical SAM
FLM25_RS24850	COG3119	arylsulfatase activity
FLM25_RS24860	COG0516	GMP reductase activity
FLM25_RS24860	COG0517	IMP dehydrogenase activity
FLM25_RS24870	COG1645	bacterial-type flagellum-dependent swarming motility
FLM25_RS24890	COG2976	Protein conserved in bacteria
FLM25_RS24920	COG4953	penicillin-binding protein 1C
FLM25_RS24925	COG2373	Large extracellular alpha-helical protein
FLM25_RS24930	COG2897	thiosulfate sulfurtransferase activity
FLM25_RS24950	COG2975	iron-sulfur cluster assembly
FLM25_RS24955	COG0633	Ferredoxin
FLM25_RS24975	COG0822	iron-sulfur transferase activity
FLM25_RS25005	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FLM25_RS25010	COG3683	transport system, periplasmic component
FLM25_RS25015	COG3711	transcriptional antiterminator
FLM25_RS25020	COG2814	Major facilitator Superfamily
FLM25_RS25025	COG2017	converts alpha-aldose to the beta-anomer
FLM25_RS25030	COG2814	Major facilitator Superfamily
FLM25_RS25030	COG0477	Major facilitator Superfamily
FLM25_RS25035	COG0457	Tetratricopeptide repeat
FLM25_RS25040	COG1940	carbohydrate kinase activity
FLM25_RS25045	COG2259	Doxx family
FLM25_RS25055	COG1017	nitric oxide dioxygenase activity
FLM25_RS25055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FLM25_RS25060	COG0347	Belongs to the P(II) protein family
FLM25_RS25065	COG2204	response regulator
FLM25_RS25070	COG3170	Tfp pilus assembly protein FimV
FLM25_RS25075	COG2205	protein histidine kinase activity
FLM25_RS25080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLM25_RS25080	COG0047	phosphoribosylformylglycinamidine synthase activity
FLM25_RS25095	COG0560	Phosphoserine phosphatase
FLM25_RS25100	COG1737	Transcriptional regulator
FLM25_RS25105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FLM25_RS25115	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FLM25_RS25135	COG0681	Belongs to the peptidase S26 family
FLM25_RS25145	COG3086	response to oxidative stress
FLM25_RS25150	COG3026	antisigma factor binding
FLM25_RS25155	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FLM25_RS25170	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FLM25_RS25180	COG0513	Belongs to the DEAD box helicase family
FLM25_RS25195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLM25_RS25200	COG3118	belongs to the thioredoxin family
FLM25_RS25215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLM25_RS25220	COG5544	Lipoprotein
FLM25_RS25225	COG0477	Major facilitator Superfamily
FLM25_RS25250	COG0542	response to heat
FLM25_RS25265	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FLM25_RS25270	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FLM25_RS25280	COG0077	Prephenate dehydratase
FLM25_RS25280	COG1605	Chorismate mutase
FLM25_RS25290	COG1605	Chorismate mutase
FLM25_RS25290	COG0287	Prephenate dehydrogenase
FLM25_RS25295	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FLM25_RS25305	COG2199	diguanylate cyclase activity
FLM25_RS25310	COG2885	chlorophyll binding
FLM25_RS25345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FLM25_RS25350	COG4137	Cytochrome C assembly protein
FLM25_RS25355	COG4536	flavin adenine dinucleotide binding
FLM25_RS25370	COG0497	DNA recombination
FLM25_RS25385	COG2867	negative regulation of translational initiation
FLM25_RS25550	COG4695	Portal protein
FLM25_RS25595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FLM25_RS25630	COG4974	Belongs to the 'phage' integrase family
FLM25_RS25655	COG3708	Transcriptional regulator
FLM25_RS25655	COG2207	Transcriptional regulator
FLM25_RS25660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLM25_RS25695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM25_RS25705	COG0235	Class ii aldolase
FLM25_RS25715	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS25730	COG2197	response regulator
FLM25_RS25735	COG3539	Fimbrial protein
FLM25_RS25745	COG3188	usher protein
FLM25_RS25765	COG3121	Chaperone
FLM25_RS25770	COG3539	Fimbrial protein
FLM25_RS25775	COG1012	belongs to the aldehyde dehydrogenase family
FLM25_RS25780	COG3284	Transcriptional regulator
FLM25_RS25785	COG0583	DNA-binding transcription factor activity
FLM25_RS25795	COG0640	Transcriptional regulator
FLM25_RS25800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLM25_RS25815	COG2916	Histone family protein nucleoid-structuring protein H-NS
FLM25_RS25830	COG4575	ribosome binding
FLM25_RS25835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLM25_RS25840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLM25_RS25845	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FLM25_RS25855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLM25_RS25870	COG4176	ABC-type proline glycine betaine transport system permease component
FLM25_RS25880	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FLM25_RS25890	COG1846	Transcriptional regulator
FLM25_RS25895	COG1566	PFAM secretion protein HlyD family protein
FLM25_RS25900	COG2814	Major facilitator Superfamily
FLM25_RS25905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FLM25_RS25925	COG1238	metal cluster binding
FLM25_RS25930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FLM25_RS25935	COG2823	Periplasmic or secreted lipoprotein
FLM25_RS25965	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FLM25_RS25985	COG1546	Belongs to the CinA family
FLM25_RS25995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLM25_RS26000	COG1121	(ABC) transporter
FLM25_RS26005	COG2951	lytic endotransglycosylase activity
FLM25_RS26010	COG3730	PTS system glucitol sorbitol-specific
FLM25_RS26015	COG3732	PTS system glucitol sorbitol-specific
FLM25_RS26025	COG1028	Short-chain dehydrogenase reductase Sdr
FLM25_RS26030	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM25_RS26035	COG1349	DNA-binding transcription factor activity
FLM25_RS26060	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FLM25_RS26065	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FLM25_RS26070	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FLM25_RS26075	COG1609	Transcriptional regulator
FLM25_RS26080	COG1263	PTS System
FLM25_RS26080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity