locus-tag	class	description
HJW74_RS00020	COG0187	DNA topoisomerase II activity
HJW74_RS00025	COG0561	phosphatase activity
HJW74_RS00040	COG2186	Transcriptional regulator
HJW74_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
HJW74_RS00050	COG0800	Aldolase
HJW74_RS00060	COG2271	Major facilitator Superfamily
HJW74_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
HJW74_RS00070	COG5645	(Lipo)protein
HJW74_RS00095	COG2188	Transcriptional regulator
HJW74_RS00110	COG2149	membrane
HJW74_RS00130	COG2610	gluconate transmembrane transporter activity
HJW74_RS00140	COG0583	DNA-binding transcription factor activity
HJW74_RS00145	COG2814	Major facilitator Superfamily
HJW74_RS00175	COG0028	Belongs to the TPP enzyme family
HJW74_RS00180	COG0440	acetolactate synthase activity
HJW74_RS00185	COG2197	response regulator
HJW74_RS00195	COG2271	Major facilitator Superfamily
HJW74_RS00235	COG2188	Transcriptional regulator
HJW74_RS00260	COG4580	involved in the transport of maltose and maltodextrins
HJW74_RS00265	COG1447	Phosphotransferase system cellobiose-specific component IIA
HJW74_RS00270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS00270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS00280	COG1609	Transcriptional regulator
HJW74_RS00290	COG3384	dioxygenase
HJW74_RS00295	COG0583	DNA-binding transcription factor activity
HJW74_RS00300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HJW74_RS00305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HJW74_RS00310	COG2828	Protein conserved in bacteria
HJW74_RS00325	COG0697	spore germination
HJW74_RS00330	COG1263	PTS System
HJW74_RS00330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJW74_RS00340	COG2814	Major facilitator Superfamily
HJW74_RS00350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJW74_RS00385	COG0583	DNA-binding transcription factor activity
HJW74_RS00410	COG1464	Belongs to the NlpA lipoprotein family
HJW74_RS00425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HJW74_RS00435	COG1064	alcohol dehydrogenase
HJW74_RS00465	COG2211	Major facilitator Superfamily
HJW74_RS00470	COG1501	Belongs to the glycosyl hydrolase 31 family
HJW74_RS00480	COG1486	melibiose metabolic process
HJW74_RS00485	COG1263	PTS System
HJW74_RS00485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJW74_RS00490	COG2982	Protein involved in outer membrane biogenesis
HJW74_RS00495	COG2233	PERMEase
HJW74_RS00500	COG0786	glutamate:sodium symporter activity
HJW74_RS00520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HJW74_RS00545	COG3152	Membrane
HJW74_RS00555	COG1494	fructose-1,6-bisphosphatase
HJW74_RS00560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HJW74_RS00565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HJW74_RS00570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HJW74_RS00590	COG2860	membrane
HJW74_RS00600	COG2169	Transcriptional regulator
HJW74_RS00600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HJW74_RS00625	COG1561	YicC-like family, N-terminal region
HJW74_RS00650	COG1131	(ABC) transporter
HJW74_RS00655	COG0842	Transport permease protein
HJW74_RS00680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HJW74_RS00715	COG1519	Transferase
HJW74_RS00725	COG0438	transferase activity, transferring glycosyl groups
HJW74_RS00735	COG0859	PFAM glycosyl transferase family 9
HJW74_RS00760	COG0859	PFAM glycosyl transferase family 9
HJW74_RS00775	COG0156	8-amino-7-oxononanoate synthase activity
HJW74_RS00785	COG0463	Glycosyl transferase, family 2
HJW74_RS00790	COG2861	carbohydrate metabolic process
HJW74_RS00795	COG4942	peptidase
HJW74_RS00805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HJW74_RS00810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HJW74_RS00830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HJW74_RS00840	COG2186	Transcriptional regulator
HJW74_RS00860	COG3722	fumarate hydratase activity
HJW74_RS00880	COG1566	PFAM secretion protein HlyD family protein
HJW74_RS00885	COG0625	glutathione transferase activity
HJW74_RS00895	COG3276	selenocysteine insertion sequence binding
HJW74_RS00900	COG1414	Transcriptional regulator
HJW74_RS00905	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HJW74_RS00910	COG3977	Valine--pyruvate aminotransferase
HJW74_RS00915	COG0366	Alpha amylase catalytic
HJW74_RS00920	COG2992	FlgJ-related protein
HJW74_RS00925	COG1609	Transcriptional regulator
HJW74_RS00925	COG2207	Transcriptional regulator
HJW74_RS00930	COG4214	carbohydrate transport
HJW74_RS00940	COG4213	ABC transporter substrate-binding protein
HJW74_RS00955	COG4682	membrane
HJW74_RS00960	COG4682	membrane
HJW74_RS00965	COG3274	enterobacterial common antigen metabolic process
HJW74_RS00995	COG1278	Cold shock
HJW74_RS01000	COG2944	sequence-specific DNA binding
HJW74_RS01005	COG2814	Major facilitator Superfamily
HJW74_RS01025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJW74_RS01035	COG1609	Transcriptional regulator
HJW74_RS01045	COG2885	chlorophyll binding
HJW74_RS01050	COG0243	molybdopterin cofactor binding
HJW74_RS01055	COG0456	acetyltransferase
HJW74_RS01060	COG2818	Glycosylase
HJW74_RS01065	COG5571	outer membrane autotransporter
HJW74_RS01070	COG2223	nitrite transmembrane transporter activity
HJW74_RS01100	COG0747	negative chemotaxis
HJW74_RS01105	COG0601	transmembrane transport
HJW74_RS01110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HJW74_RS01115	COG0444	Belongs to the ABC transporter superfamily
HJW74_RS01120	COG4608	Belongs to the ABC transporter superfamily
HJW74_RS01135	COG2894	cell division
HJW74_RS01145	COG1215	transferase activity, transferring glycosyl groups
HJW74_RS01150	COG0457	Tetratricopeptide repeat
HJW74_RS01165	COG2194	sulfuric ester hydrolase activity
HJW74_RS01195	COG1215	transferase activity, transferring glycosyl groups
HJW74_RS01200	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HJW74_RS01205	COG0457	Tetratricopeptide repeat
HJW74_RS01205	COG3118	belongs to the thioredoxin family
HJW74_RS01210	COG2199	diguanylate cyclase activity
HJW74_RS01210	COG2200	EAL domain
HJW74_RS01220	COG0612	Peptidase, M16
HJW74_RS01235	COG2982	Protein involved in outer membrane biogenesis
HJW74_RS01240	COG0477	Major facilitator Superfamily
HJW74_RS01245	COG1295	ribonuclease BN
HJW74_RS01250	COG0583	DNA-binding transcription factor activity
HJW74_RS01255	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS01260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HJW74_RS01270	COG1454	alcohol dehydrogenase
HJW74_RS01280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HJW74_RS01285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HJW74_RS01290	COG0671	phosphoesterase, PA-phosphatase related
HJW74_RS01310	COG0589	response to stress
HJW74_RS01320	COG0306	phosphate transporter
HJW74_RS01325	COG2081	HI0933 family
HJW74_RS01330	COG2239	Acts as a magnesium transporter
HJW74_RS01340	COG1124	(ABC) transporter
HJW74_RS01350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HJW74_RS01355	COG0601	transmembrane transport
HJW74_RS01360	COG0747	negative chemotaxis
HJW74_RS01370	COG3479	Phenolic acid decarboxylase
HJW74_RS01410	COG0628	permease
HJW74_RS01415	COG0477	Major facilitator Superfamily
HJW74_RS01425	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HJW74_RS01440	COG3714	YhhN family
HJW74_RS01450	COG3776	membrane
HJW74_RS01455	COG0742	ribosomal rna small subunit methyltransferase
HJW74_RS01460	COG0552	protein localization to endoplasmic reticulum
HJW74_RS01465	COG2884	Cell division ATP-binding protein ftsE
HJW74_RS01470	COG2177	Part of the ABC transporter FtsEX involved in
HJW74_RS01485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HJW74_RS01495	COG0683	leucine binding
HJW74_RS01505	COG0683	leucine binding
HJW74_RS01510	COG0559	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS01560	COG0584	glycerophosphoryl diester phosphodiesterase
HJW74_RS01570	COG0405	Gamma-glutamyltransferase
HJW74_RS01575	COG1247	-acetyltransferase
HJW74_RS01585	COG0673	inositol 2-dehydrogenase activity
HJW74_RS01590	COG1741	Belongs to the pirin family
HJW74_RS01595	COG1609	Transcriptional regulator
HJW74_RS01600	COG3265	gluconokinase activity
HJW74_RS01605	COG2610	gluconate transmembrane transporter activity
HJW74_RS01615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HJW74_RS01640	COG0058	SHG alpha-glucan phosphorylase activity
HJW74_RS01655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HJW74_RS01670	COG1349	DNA-binding transcription factor activity
HJW74_RS01680	COG0058	SHG alpha-glucan phosphorylase activity
HJW74_RS01685	COG1640	4-alpha-glucanotransferase
HJW74_RS01690	COG2610	gluconate transmembrane transporter activity
HJW74_RS01700	COG1040	competence protein
HJW74_RS01725	COG1918	ferrous iron import across plasma membrane
HJW74_RS01730	COG2183	response to ionizing radiation
HJW74_RS01735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HJW74_RS01740	COG0745	RESPONSE REGULATOR receiver
HJW74_RS01760	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HJW74_RS01765	COG1011	Hydrolase
HJW74_RS01775	COG0494	nUDIX hydrolase
HJW74_RS01780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HJW74_RS01805	COG4796	Type ii and iii secretion system protein
HJW74_RS01820	COG3266	domain, Protein
HJW74_RS01825	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HJW74_RS01830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HJW74_RS01855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HJW74_RS01865	COG0402	S-adenosylhomocysteine deaminase activity
HJW74_RS01870	COG0738	Major facilitator superfamily
HJW74_RS01895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HJW74_RS01900	COG1289	transmembrane transporter activity
HJW74_RS01910	COG1765	OsmC-like protein
HJW74_RS01915	COG3954	Phosphoribulokinase
HJW74_RS01925	COG0429	hydrolase of the alpha beta-hydrolase fold
HJW74_RS01935	COG0488	(ABC) transporter
HJW74_RS01950	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HJW74_RS01955	COG1047	Peptidyl-prolyl cis-trans
HJW74_RS01965	COG0545	Peptidyl-prolyl cis-trans isomerase
HJW74_RS01970	COG2964	Protein conserved in bacteria
HJW74_RS02025	COG0051	transcription antitermination factor activity, RNA binding
HJW74_RS02050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HJW74_RS02065	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HJW74_RS02130	COG0201	protein transport
HJW74_RS02155	COG0202	RNA polymerase activity
HJW74_RS02170	COG0789	Transcriptional regulator
HJW74_RS02175	COG3036	rescue of stalled ribosome
HJW74_RS02205	COG0758	DNA mediated transformation
HJW74_RS02215	COG0551	DNA topoisomerase type I activity
HJW74_RS02235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HJW74_RS02270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJW74_RS02275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJW74_RS02280	COG1309	transcriptional regulator
HJW74_RS02300	COG4145	pantothenate transmembrane transporter activity
HJW74_RS02305	COG3924	membrane
HJW74_RS02310	COG0439	Biotin carboxylase
HJW74_RS02315	COG0511	ligase activity, forming carbon-carbon bonds
HJW74_RS02340	COG2200	EAL domain
HJW74_RS02340	COG2199	diguanylate cyclase activity
HJW74_RS02345	COG1077	Cell shape determining protein MreB Mrl
HJW74_RS02350	COG1792	Involved in formation and maintenance of cell shape
HJW74_RS02355	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HJW74_RS02365	COG1530	ribonuclease E activity
HJW74_RS02370	COG3164	Protein of unknown function
HJW74_RS02375	COG0312	modulator of DNA gyrase
HJW74_RS02380	COG0583	DNA-binding transcription factor activity
HJW74_RS02395	COG1289	transmembrane transporter activity
HJW74_RS02400	COG2732	(Barnase) inhibitor
HJW74_RS02425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HJW74_RS02430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HJW74_RS02435	COG3105	Protein conserved in bacteria
HJW74_RS02440	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HJW74_RS02460	COG0625	glutathione transferase activity
HJW74_RS02465	COG2969	positive regulation of protein catabolic process
HJW74_RS02475	COG0493	'glutamate synthase
HJW74_RS02480	COG0067	glutamate synthase
HJW74_RS02480	COG0069	glutamate synthase activity
HJW74_RS02480	COG0070	glutamate synthase
HJW74_RS02485	COG1242	4 iron, 4 sulfur cluster binding
HJW74_RS02490	COG2271	Major facilitator Superfamily
HJW74_RS02495	COG1063	alcohol dehydrogenase
HJW74_RS02505	COG1312	Catalyzes the dehydration of D-mannonate
HJW74_RS02510	COG2198	Histidine kinase
HJW74_RS02510	COG5002	protein histidine kinase activity
HJW74_RS02510	COG0784	Response regulator, receiver
HJW74_RS02515	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HJW74_RS02520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HJW74_RS02525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS02535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS02540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HJW74_RS02545	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HJW74_RS02550	COG1137	ATPase activity
HJW74_RS02555	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HJW74_RS02560	COG3117	lipopolysaccharide transmembrane transporter activity
HJW74_RS02565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HJW74_RS02575	COG0530	calcium, potassium:sodium antiporter activity
HJW74_RS02580	COG1127	ABC transporter
HJW74_RS02585	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HJW74_RS02590	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HJW74_RS02595	COG2854	intermembrane phospholipid transfer
HJW74_RS02600	COG3113	response to antibiotic
HJW74_RS02605	COG5007	Belongs to the BolA IbaG family
HJW74_RS02615	COG3423	Transcriptional regulator
HJW74_RS02620	COG0142	geranyltranstransferase activity
HJW74_RS02635	COG0697	spore germination
HJW74_RS02645	COG2027	D-alanyl-D-alanine carboxypeptidase
HJW74_RS02655	COG1534	Rna-binding protein
HJW74_RS02665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HJW74_RS02670	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HJW74_RS02680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HJW74_RS02725	COG0195	Participates in both transcription termination and antitermination
HJW74_RS02770	COG0814	amino acid
HJW74_RS02775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJW74_RS02780	COG0826	peptidase U32
HJW74_RS02785	COG0826	peptidase U32
HJW74_RS02790	COG3154	lipid carrier protein
HJW74_RS02795	COG3153	acetyltransferase
HJW74_RS02810	COG0693	protein deglycase activity
HJW74_RS02815	COG0702	epimerase
HJW74_RS02820	COG0701	Predicted permease
HJW74_RS02825	COG2823	Periplasmic or secreted lipoprotein
HJW74_RS02845	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HJW74_RS02860	COG1063	alcohol dehydrogenase
HJW74_RS02865	COG3775	system Galactitol-specific IIC component
HJW74_RS02870	COG3414	Phosphotransferase system galactitol-specific IIB component
HJW74_RS02875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS02885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS02885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS02890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJW74_RS02890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJW74_RS02890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS02895	COG1105	Belongs to the carbohydrate kinase PfkB family
HJW74_RS02910	COG1349	DNA-binding transcription factor activity
HJW74_RS02915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJW74_RS02920	COG2721	sulfolactate sulfo-lyase activity
HJW74_RS02930	COG2271	Major facilitator Superfamily
HJW74_RS02940	COG2084	Dehydrogenase
HJW74_RS02945	COG1929	Belongs to the glycerate kinase type-1 family
HJW74_RS02975	COG1741	Belongs to the pirin family
HJW74_RS02980	COG0583	DNA-binding transcription factor activity
HJW74_RS02985	COG3152	Membrane
HJW74_RS02990	COG0435	Glutathione S-transferase
HJW74_RS02995	COG2259	Doxx family
HJW74_RS03005	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HJW74_RS03010	COG4575	ribosome binding
HJW74_RS03015	COG1422	Protein of unknown function (DUF1090)
HJW74_RS03025	COG0586	Pfam SNARE associated Golgi protein
HJW74_RS03030	COG2186	Transcriptional regulator
HJW74_RS03035	COG2271	Major facilitator Superfamily
HJW74_RS03045	COG2721	sulfolactate sulfo-lyase activity
HJW74_RS03060	COG0861	Integral membrane protein TerC family
HJW74_RS03065	COG0673	inositol 2-dehydrogenase activity
HJW74_RS03070	COG1451	nucleotide metabolic process
HJW74_RS03090	COG0446	pyridine nucleotide-disulphide oxidoreductase
HJW74_RS03090	COG1902	pentaerythritol trinitrate reductase activity
HJW74_RS03140	COG1695	Transcriptional regulator
HJW74_RS03150	COG2375	cellular response to nickel ion
HJW74_RS03165	COG1461	Dihydroxyacetone kinase
HJW74_RS03170	COG2376	Dihydroxyacetone kinase
HJW74_RS03240	COG3247	response to pH
HJW74_RS03250	COG2205	protein histidine kinase activity
HJW74_RS03250	COG2198	Histidine kinase
HJW74_RS03250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJW74_RS03250	COG0784	Response regulator, receiver
HJW74_RS03255	COG2197	response regulator
HJW74_RS03280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HJW74_RS03285	COG0358	DNA primase activity
HJW74_RS03290	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HJW74_RS03355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HJW74_RS03370	COG4991	sh3 domain protein
HJW74_RS03375	COG3025	triphosphatase activity
HJW74_RS03400	COG2960	long-chain fatty acid transporting porin activity
HJW74_RS03415	COG3384	dioxygenase
HJW74_RS03420	COG0754	glutathionylspermidine amidase activity
HJW74_RS03435	COG0494	nUDIX hydrolase
HJW74_RS03440	COG3151	Protein conserved in bacteria
HJW74_RS03445	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HJW74_RS03450	COG3150	esterase
HJW74_RS03460	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HJW74_RS03465	COG2249	NAD(P)H dehydrogenase (quinone) activity
HJW74_RS03470	COG0642	Histidine kinase
HJW74_RS03480	COG3111	PFAM Bacterial OB fold (BOF) protein
HJW74_RS03485	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HJW74_RS03490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HJW74_RS03495	COG0204	Acyl-transferase
HJW74_RS03500	COG2132	Multicopper oxidase
HJW74_RS03505	COG1032	radical SAM domain protein
HJW74_RS03515	COG0656	L-ascorbic acid biosynthetic process
HJW74_RS03520	COG1979	alcohol dehydrogenase
HJW74_RS03525	COG2207	Transcriptional regulator
HJW74_RS03530	COG0586	Pfam SNARE associated Golgi protein
HJW74_RS03535	COG0626	cystathionine gamma-synthase activity
HJW74_RS03545	COG0848	biopolymer transport protein
HJW74_RS03550	COG2211	Major facilitator Superfamily
HJW74_RS03575	COG0625	glutathione transferase activity
HJW74_RS03590	COG0754	glutathionylspermidine amidase activity
HJW74_RS03595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HJW74_RS03615	COG0583	DNA-binding transcription factor activity
HJW74_RS03620	COG0626	cystathionine gamma-synthase activity
HJW74_RS03635	COG1811	Na channel or pump
HJW74_RS03640	COG1982	Orn Lys Arg decarboxylase major
HJW74_RS03645	COG2211	Major facilitator Superfamily
HJW74_RS03660	COG1194	a g-specific adenine glycosylase
HJW74_RS03670	COG3171	Protein conserved in bacteria
HJW74_RS03680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HJW74_RS03695	COG0762	integral membrane protein
HJW74_RS03700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HJW74_RS03705	COG2805	Type II/IV secretion system protein
HJW74_RS03730	COG0189	ligase activity
HJW74_RS03735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HJW74_RS03740	COG2356	endonuclease I
HJW74_RS03750	COG2814	Major facilitator Superfamily
HJW74_RS03785	COG2146	nitrite reductase [NAD(P)H] activity
HJW74_RS03800	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS03805	COG1414	Transcriptional regulator
HJW74_RS03835	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS03840	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HJW74_RS03860	COG0501	Belongs to the peptidase M48B family
HJW74_RS03865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HJW74_RS03880	COG0191	fructose-bisphosphate aldolase activity
HJW74_RS03885	COG0668	transmembrane transport
HJW74_RS03895	COG2968	Membrane
HJW74_RS03915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HJW74_RS03920	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HJW74_RS03940	COG0006	proline dipeptidase activity
HJW74_RS03945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HJW74_RS03950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HJW74_RS03970	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS03975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HJW74_RS03995	COG2723	6-phospho-beta-galactosidase activity
HJW74_RS04000	COG1737	Transcriptional regulator
HJW74_RS04010	COG1272	protein, Hemolysin III
HJW74_RS04020	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HJW74_RS04030	COG0716	FMN binding
HJW74_RS04035	COG4974	Belongs to the 'phage' integrase family
HJW74_RS04045	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HJW74_RS04070	COG4942	peptidase
HJW74_RS04080	COG2814	Major facilitator Superfamily
HJW74_RS04095	COG0667	Aldo Keto reductase
HJW74_RS04130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HJW74_RS04135	COG1393	Belongs to the ArsC family
HJW74_RS04140	COG3104	oligopeptide transport
HJW74_RS04150	COG1538	Outer membrane efflux protein
HJW74_RS04155	COG1289	transmembrane transporter activity
HJW74_RS04170	COG3592	Divergent 4Fe-4S mono-cluster
HJW74_RS04175	COG2388	GCN5-related N-acetyl-transferase
HJW74_RS04185	COG3539	Fimbrial protein
HJW74_RS04190	COG3539	Fimbrial protein
HJW74_RS04195	COG3539	Fimbrial protein
HJW74_RS04200	COG3188	usher protein
HJW74_RS04205	COG3121	Chaperone
HJW74_RS04210	COG3539	Fimbrial protein
HJW74_RS04225	COG4974	Belongs to the 'phage' integrase family
HJW74_RS04230	COG0582	viral genome integration into host DNA
HJW74_RS04235	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HJW74_RS04240	COG1846	Transcriptional regulator
HJW74_RS04245	COG0697	spore germination
HJW74_RS04295	COG0667	Aldo Keto reductase
HJW74_RS04300	COG0814	amino acid
HJW74_RS04315	COG0183	Belongs to the thiolase family
HJW74_RS04325	COG0823	Involved in the tonB-independent uptake of proteins
HJW74_RS04335	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS04340	COG2814	Major facilitator Superfamily
HJW74_RS04375	COG3842	ATPase activity
HJW74_RS04380	COG0395	ABC-type sugar transport system, permease component
HJW74_RS04385	COG1175	transmembrane transport
HJW74_RS04390	COG1917	Cupin 2, conserved barrel domain protein
HJW74_RS04395	COG1794	racemase activity, acting on amino acids and derivatives
HJW74_RS04400	COG0583	DNA-binding transcription factor activity
HJW74_RS04410	COG1609	Transcriptional regulator
HJW74_RS04415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS04420	COG2723	6-phospho-beta-galactosidase activity
HJW74_RS04425	COG2186	Transcriptional regulator
HJW74_RS04435	COG1609	Transcriptional regulator
HJW74_RS04450	COG0667	Aldo Keto reductase
HJW74_RS04460	COG0861	Integral membrane protein TerC family
HJW74_RS04495	COG2165	general secretion pathway protein
HJW74_RS04500	COG4795	General secretion pathway protein
HJW74_RS04510	COG4967	type IV pilus modification protein PilV
HJW74_RS04515	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HJW74_RS04520	COG1025	Belongs to the peptidase M16 family
HJW74_RS04525	COG1074	ATP-dependent DNA helicase activity
HJW74_RS04530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HJW74_RS04540	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HJW74_RS04540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HJW74_RS04545	COG0860	N-Acetylmuramoyl-L-alanine amidase
HJW74_RS04550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HJW74_RS04580	COG4656	Part of a membrane complex involved in electron transport
HJW74_RS04585	COG1454	alcohol dehydrogenase
HJW74_RS04585	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS04840	COG2885	chlorophyll binding
HJW74_RS04870	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HJW74_RS04875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HJW74_RS04880	COG2166	iron-sulfur cluster assembly
HJW74_RS04885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HJW74_RS04895	COG0583	DNA-binding transcription factor activity
HJW74_RS04900	COG2363	Small membrane protein
HJW74_RS04910	COG1349	DNA-binding transcription factor activity
HJW74_RS04930	COG0738	Major facilitator superfamily
HJW74_RS04940	COG0235	Class ii aldolase
HJW74_RS04945	COG1454	alcohol dehydrogenase
HJW74_RS04965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJW74_RS04980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HJW74_RS04985	COG2011	ABC-type metal ion transport system permease component
HJW74_RS04990	COG1464	Belongs to the NlpA lipoprotein family
HJW74_RS04995	COG0477	Major facilitator Superfamily
HJW74_RS05005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HJW74_RS05010	COG1760	l-serine dehydratase
HJW74_RS05015	COG0814	amino acid
HJW74_RS05020	COG1611	Belongs to the LOG family
HJW74_RS05035	COG3098	single-species biofilm formation
HJW74_RS05040	COG0564	pseudouridine synthase activity
HJW74_RS05045	COG0716	FMN binding
HJW74_RS05050	COG2271	Major facilitator Superfamily
HJW74_RS05055	COG4948	Mandelate Racemase Muconate Lactonizing
HJW74_RS05060	COG4948	Mandelate Racemase Muconate Lactonizing
HJW74_RS05065	COG1929	Belongs to the glycerate kinase type-1 family
HJW74_RS05070	COG2205	protein histidine kinase activity
HJW74_RS05070	COG3437	response regulator, receiver
HJW74_RS05070	COG3850	Histidine kinase
HJW74_RS05070	COG4999	Histidine kinase
HJW74_RS05080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HJW74_RS05085	COG3956	TIGRFAM MazG family protein
HJW74_RS05110	COG0602	queuosine metabolic process
HJW74_RS05115	COG0720	synthase
HJW74_RS05135	COG2234	aminopeptidase activity
HJW74_RS05195	COG4942	peptidase
HJW74_RS05195	COG1388	LysM domain
HJW74_RS05200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HJW74_RS05225	COG0163	prenyltransferase activity
HJW74_RS05230	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HJW74_RS05250	COG0582	viral genome integration into host DNA
HJW74_RS05290	COG5290	Psort location Cytoplasmic, score
HJW74_RS05315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJW74_RS05320	COG4558	Periplasmic binding protein
HJW74_RS05325	COG3720	iron ion transport
HJW74_RS05345	COG0679	Auxin Efflux Carrier
HJW74_RS05360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HJW74_RS05365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HJW74_RS05370	COG1121	(ABC) transporter
HJW74_RS05375	COG0803	Belongs to the bacterial solute-binding protein 9 family
HJW74_RS05380	COG1609	Transcriptional regulator
HJW74_RS05385	COG1940	carbohydrate kinase activity
HJW74_RS05390	COG1447	Phosphotransferase system cellobiose-specific component IIA
HJW74_RS05395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS05400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS05405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS05410	COG4580	involved in the transport of maltose and maltodextrins
HJW74_RS05420	COG2723	6-phospho-beta-galactosidase activity
HJW74_RS05430	COG0309	Hydrogenase expression formation protein (HypE)
HJW74_RS05435	COG0409	Hydrogenase expression formation protein
HJW74_RS05440	COG0298	carbon dioxide binding
HJW74_RS05445	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HJW74_RS05460	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HJW74_RS05465	COG0651	ATP synthesis coupled electron transport
HJW74_RS05470	COG0650	Formate hydrogenlyase subunit 4
HJW74_RS05475	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HJW74_RS05475	COG3261	NADH dehydrogenase
HJW74_RS05480	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HJW74_RS05485	COG3260	NADH ubiquinone oxidoreductase 20
HJW74_RS05495	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HJW74_RS05505	COG2723	6-phospho-beta-galactosidase activity
HJW74_RS05510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJW74_RS05510	COG1263	PTS System
HJW74_RS05520	COG1609	Transcriptional regulator
HJW74_RS05525	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HJW74_RS05530	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HJW74_RS05535	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HJW74_RS05565	COG1349	DNA-binding transcription factor activity
HJW74_RS05570	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS05575	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS05585	COG3732	PTS system glucitol sorbitol-specific
HJW74_RS05590	COG3730	PTS system glucitol sorbitol-specific
HJW74_RS05595	COG2951	lytic endotransglycosylase activity
HJW74_RS05600	COG1121	(ABC) transporter
HJW74_RS05605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HJW74_RS05615	COG1546	Belongs to the CinA family
HJW74_RS05635	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HJW74_RS05670	COG2823	Periplasmic or secreted lipoprotein
HJW74_RS05675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HJW74_RS05680	COG1238	metal cluster binding
HJW74_RS05700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HJW74_RS05705	COG2814	Major facilitator Superfamily
HJW74_RS05710	COG1566	PFAM secretion protein HlyD family protein
HJW74_RS05720	COG1846	Transcriptional regulator
HJW74_RS05735	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HJW74_RS05745	COG4176	ABC-type proline glycine betaine transport system permease component
HJW74_RS05760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HJW74_RS05770	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HJW74_RS05775	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HJW74_RS05780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HJW74_RS05785	COG4575	ribosome binding
HJW74_RS05805	COG2916	Histone family protein nucleoid-structuring protein H-NS
HJW74_RS05825	COG0640	Transcriptional regulator
HJW74_RS05835	COG0583	DNA-binding transcription factor activity
HJW74_RS05840	COG3284	Transcriptional regulator
HJW74_RS05845	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS05850	COG3539	Fimbrial protein
HJW74_RS05855	COG3121	Chaperone
HJW74_RS05875	COG3188	usher protein
HJW74_RS05885	COG3539	Fimbrial protein
HJW74_RS05890	COG2197	response regulator
HJW74_RS05905	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS05915	COG0235	Class ii aldolase
HJW74_RS05925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJW74_RS05960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJW74_RS05965	COG2207	Transcriptional regulator
HJW74_RS05965	COG3708	Transcriptional regulator
HJW74_RS05990	COG2801	Transposase and inactivated derivatives
HJW74_RS06005	COG0582	viral genome integration into host DNA
HJW74_RS06020	COG2867	negative regulation of translational initiation
HJW74_RS06040	COG0497	DNA recombination
HJW74_RS06055	COG4536	flavin adenine dinucleotide binding
HJW74_RS06060	COG4137	Cytochrome C assembly protein
HJW74_RS06065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HJW74_RS06105	COG2885	chlorophyll binding
HJW74_RS06110	COG2199	diguanylate cyclase activity
HJW74_RS06120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HJW74_RS06125	COG1605	Chorismate mutase
HJW74_RS06125	COG0287	Prephenate dehydrogenase
HJW74_RS06135	COG1605	Chorismate mutase
HJW74_RS06135	COG0077	Prephenate dehydratase
HJW74_RS06145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HJW74_RS06150	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HJW74_RS06165	COG0542	response to heat
HJW74_RS06190	COG0477	Major facilitator Superfamily
HJW74_RS06195	COG5544	Lipoprotein
HJW74_RS06200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HJW74_RS06215	COG3118	belongs to the thioredoxin family
HJW74_RS06220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HJW74_RS06235	COG0513	Belongs to the DEAD box helicase family
HJW74_RS06245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HJW74_RS06260	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HJW74_RS06265	COG3026	antisigma factor binding
HJW74_RS06270	COG3086	response to oxidative stress
HJW74_RS06280	COG0681	Belongs to the peptidase S26 family
HJW74_RS06300	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HJW74_RS06310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HJW74_RS06315	COG1737	Transcriptional regulator
HJW74_RS06320	COG0560	Phosphoserine phosphatase
HJW74_RS06335	COG0047	phosphoribosylformylglycinamidine synthase activity
HJW74_RS06335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HJW74_RS06340	COG2205	protein histidine kinase activity
HJW74_RS06345	COG3170	Tfp pilus assembly protein FimV
HJW74_RS06350	COG2204	response regulator
HJW74_RS06355	COG0347	Belongs to the P(II) protein family
HJW74_RS06360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HJW74_RS06360	COG1017	nitric oxide dioxygenase activity
HJW74_RS06370	COG2259	Doxx family
HJW74_RS06375	COG1940	carbohydrate kinase activity
HJW74_RS06380	COG0457	Tetratricopeptide repeat
HJW74_RS06385	COG2814	Major facilitator Superfamily
HJW74_RS06385	COG0477	Major facilitator Superfamily
HJW74_RS06390	COG2017	converts alpha-aldose to the beta-anomer
HJW74_RS06395	COG2814	Major facilitator Superfamily
HJW74_RS06400	COG3711	transcriptional antiterminator
HJW74_RS06405	COG3683	transport system, periplasmic component
HJW74_RS06410	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HJW74_RS06440	COG0822	iron-sulfur transferase activity
HJW74_RS06460	COG0633	Ferredoxin
HJW74_RS06465	COG2975	iron-sulfur cluster assembly
HJW74_RS06485	COG2897	thiosulfate sulfurtransferase activity
HJW74_RS06490	COG2373	Large extracellular alpha-helical protein
HJW74_RS06495	COG4953	penicillin-binding protein 1C
HJW74_RS06525	COG2976	Protein conserved in bacteria
HJW74_RS06545	COG1645	bacterial-type flagellum-dependent swarming motility
HJW74_RS06555	COG0516	GMP reductase activity
HJW74_RS06555	COG0517	IMP dehydrogenase activity
HJW74_RS06570	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HJW74_RS06575	COG0210	DNA helicase
HJW74_RS06590	COG3119	arylsulfatase activity
HJW74_RS06595	COG0641	radical SAM
HJW74_RS06615	COG2200	EAL domain
HJW74_RS06630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HJW74_RS06645	COG2723	6-phospho-beta-galactosidase activity
HJW74_RS06655	COG2233	PERMEase
HJW74_RS06670	COG1393	Belongs to the ArsC family
HJW74_RS06675	COG4783	chaperone-mediated protein folding
HJW74_RS06685	COG0628	permease
HJW74_RS06690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HJW74_RS06695	COG2716	regulation of RNA biosynthetic process
HJW74_RS06705	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HJW74_RS06715	COG2321	neutral zinc metallopeptidase
HJW74_RS06720	COG1444	tRNA N-acetyltransferase activity
HJW74_RS06725	COG0400	carboxylic ester hydrolase activity
HJW74_RS06740	COG1393	Belongs to the ArsC family
HJW74_RS06750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJW74_RS06755	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HJW74_RS06755	COG0493	'glutamate synthase
HJW74_RS06765	COG5342	invasion associated locus B
HJW74_RS06770	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HJW74_RS06775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HJW74_RS06785	COG4810	utilization protein
HJW74_RS06875	COG0860	N-Acetylmuramoyl-L-alanine amidase
HJW74_RS06895	COG2837	iron assimilation
HJW74_RS06905	COG4150	thiosulfate binding
HJW74_RS06910	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HJW74_RS06915	COG4208	sulfate ABC transporter
HJW74_RS06920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HJW74_RS06930	COG4319	ketosteroid isomerase
HJW74_RS06970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HJW74_RS06995	COG0385	Bile acid
HJW74_RS07000	COG0583	DNA-binding transcription factor activity
HJW74_RS07030	COG3415	Transposase
HJW74_RS07035	COG3415	Transposase
HJW74_RS07045	COG2200	EAL domain
HJW74_RS07045	COG2199	diguanylate cyclase activity
HJW74_RS07050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HJW74_RS07065	COG0667	Aldo Keto reductase
HJW74_RS07070	COG3961	Belongs to the TPP enzyme family
HJW74_RS07085	COG3279	Response regulator of the LytR AlgR family
HJW74_RS07090	COG3275	phosphorelay sensor kinase activity
HJW74_RS07105	COG0436	Aminotransferase
HJW74_RS07115	COG2807	transmembrane transport
HJW74_RS07120	COG0590	tRNA wobble adenosine to inosine editing
HJW74_RS07125	COG0583	DNA-binding transcription factor activity
HJW74_RS07160	COG2885	chlorophyll binding
HJW74_RS07320	COG0582	viral genome integration into host DNA
HJW74_RS07385	COG1846	Transcriptional regulator
HJW74_RS07395	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HJW74_RS07400	COG1403	HNH endonuclease
HJW74_RS07430	COG3179	chitinase
HJW74_RS07455	COG4626	Terminase
HJW74_RS07455	COG1802	Transcriptional regulator
HJW74_RS07555	COG2116	formate transmembrane transporter activity
HJW74_RS07560	COG2853	Lipoprotein
HJW74_RS07570	COG3691	Protein conserved in bacteria
HJW74_RS07585	COG2062	phosphohistidine phosphatase, SixA
HJW74_RS07610	COG0730	response to heat
HJW74_RS07615	COG3101	peptidyl-lysine hydroxylation
HJW74_RS07630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HJW74_RS07650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HJW74_RS07660	COG0586	Pfam SNARE associated Golgi protein
HJW74_RS07670	COG0285	dihydrofolate synthase activity
HJW74_RS07675	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HJW74_RS07680	COG1286	toxin biosynthetic process
HJW74_RS07685	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HJW74_RS07690	COG0163	prenyltransferase activity
HJW74_RS07715	COG4160	amino acid transport
HJW74_RS07720	COG4598	ABC transporter
HJW74_RS07735	COG1090	epimerase
HJW74_RS07740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HJW74_RS07745	COG0625	glutathione transferase activity
HJW74_RS07750	COG0625	glutathione transferase activity
HJW74_RS07755	COG0622	Phosphoesterase
HJW74_RS07760	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HJW74_RS07765	COG0280	phosphate acetyltransferase
HJW74_RS07765	COG0857	belongs to the CobB CobQ family
HJW74_RS07785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HJW74_RS07790	COG0490	domain, Protein
HJW74_RS07790	COG0471	metal ion transport
HJW74_RS07800	COG0436	Aminotransferase
HJW74_RS07805	COG0583	DNA-binding transcription factor activity
HJW74_RS07855	COG0839	Belongs to the complex I subunit 6 family
HJW74_RS07865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HJW74_RS07870	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HJW74_RS07885	COG2153	protein acetylation
HJW74_RS07890	COG1169	isochorismate synthase
HJW74_RS07915	COG0318	PFAM AMP-dependent synthetase and ligase
HJW74_RS07925	COG5464	transposase or invertase
HJW74_RS07945	COG1414	Transcriptional regulator
HJW74_RS07955	COG2271	Major facilitator Superfamily
HJW74_RS07965	COG0247	lactate metabolic process
HJW74_RS07975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HJW74_RS07980	COG2271	Major facilitator Superfamily
HJW74_RS07985	COG0584	glycerophosphoryl diester phosphodiesterase
HJW74_RS07990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HJW74_RS08015	COG2205	protein histidine kinase activity
HJW74_RS08015	COG0784	Response regulator, receiver
HJW74_RS08025	COG2198	Histidine kinase
HJW74_RS08025	COG0642	Histidine kinase
HJW74_RS08040	COG2169	Transcriptional regulator
HJW74_RS08040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HJW74_RS08045	COG3145	DNA-N1-methyladenine dioxygenase activity
HJW74_RS08050	COG4615	Cyclic peptide transporter
HJW74_RS08055	COG2239	Acts as a magnesium transporter
HJW74_RS08060	COG0659	secondary active sulfate transmembrane transporter activity
HJW74_RS08075	COG0628	permease
HJW74_RS08100	COG1349	DNA-binding transcription factor activity
HJW74_RS08105	COG0494	nUDIX hydrolase
HJW74_RS08125	COG1061	Type III restriction enzyme res subunit
HJW74_RS08130	COG1187	pseudouridine synthase activity
HJW74_RS08135	COG2814	Major facilitator Superfamily
HJW74_RS08145	COG4172	Belongs to the ABC transporter superfamily
HJW74_RS08150	COG4239	(ABC) transporter, permease
HJW74_RS08155	COG4174	ABC transporter (Permease)
HJW74_RS08160	COG4166	transmembrane transport
HJW74_RS08165	COG2200	EAL domain
HJW74_RS08170	COG0791	NLP P60 protein
HJW74_RS08175	COG0671	phosphoesterase, PA-phosphatase related
HJW74_RS08180	COG0523	cobalamin synthesis protein
HJW74_RS08185	COG0246	Mannitol dehydrogenase
HJW74_RS08190	COG1312	Catalyzes the dehydration of D-mannonate
HJW74_RS08220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS08220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS08225	COG1105	Belongs to the carbohydrate kinase PfkB family
HJW74_RS08230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJW74_RS08230	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HJW74_RS08230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJW74_RS08240	COG2855	membrane
HJW74_RS08245	COG0583	DNA-binding transcription factor activity
HJW74_RS08250	COG0833	amino acid
HJW74_RS08255	COG4771	TonB-dependent receptor
HJW74_RS08270	COG2311	Membrane
HJW74_RS08285	COG1129	ABC transporter
HJW74_RS08295	COG2949	membrane
HJW74_RS08305	COG1346	cytolysis
HJW74_RS08315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HJW74_RS08320	COG3659	wide pore channel activity
HJW74_RS08335	COG2723	6-phospho-beta-galactosidase activity
HJW74_RS08340	COG1538	Outer membrane efflux protein
HJW74_RS08345	COG0586	Pfam SNARE associated Golgi protein
HJW74_RS08355	COG1686	Belongs to the peptidase S11 family
HJW74_RS08365	COG0277	FAD linked oxidase domain protein
HJW74_RS08370	COG1472	Belongs to the glycosyl hydrolase 3 family
HJW74_RS08375	COG1732	Glycine betaine
HJW74_RS08380	COG1174	glycine betaine transport
HJW74_RS08385	COG1125	glycine betaine transport
HJW74_RS08390	COG1174	glycine betaine transport
HJW74_RS08400	COG3275	phosphorelay sensor kinase activity
HJW74_RS08410	COG4807	Protein conserved in bacteria
HJW74_RS08430	COG5455	response to cobalt ion
HJW74_RS08435	COG0583	DNA-binding transcription factor activity
HJW74_RS08440	COG2252	PERMEase
HJW74_RS08450	COG0583	DNA-binding transcription factor activity
HJW74_RS08465	COG0351	phosphomethylpyrimidine kinase
HJW74_RS08470	COG1830	Aldolase
HJW74_RS08505	COG1070	Carbohydrate kinase
HJW74_RS08515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HJW74_RS08520	COG4948	Mandelate Racemase Muconate Lactonizing
HJW74_RS08525	COG0747	negative chemotaxis
HJW74_RS08530	COG0601	transmembrane transport
HJW74_RS08540	COG0444	Belongs to the ABC transporter superfamily
HJW74_RS08545	COG4608	Belongs to the ABC transporter superfamily
HJW74_RS08560	COG0745	RESPONSE REGULATOR receiver
HJW74_RS08565	COG2205	protein histidine kinase activity
HJW74_RS08590	COG1301	dicarboxylic acid transport
HJW74_RS08610	COG5002	protein histidine kinase activity
HJW74_RS08615	COG0443	Heat shock 70 kDa protein
HJW74_RS08620	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HJW74_RS08635	COG2982	Protein involved in outer membrane biogenesis
HJW74_RS08640	COG1253	flavin adenine dinucleotide binding
HJW74_RS08680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HJW74_RS08690	COG1215	transferase activity, transferring glycosyl groups
HJW74_RS08720	COG2244	polysaccharide biosynthetic process
HJW74_RS08775	COG0438	transferase activity, transferring glycosyl groups
HJW74_RS08780	COG1216	Glycosyl transferase, family 2
HJW74_RS08780	COG1442	glycosyl transferase family 8
HJW74_RS08790	COG0463	Glycosyl transferase, family 2
HJW74_RS08815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HJW74_RS08845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HJW74_RS08850	COG0583	DNA-binding transcription factor activity
HJW74_RS08860	COG0531	amino acid
HJW74_RS08865	COG0640	Transcriptional regulator
HJW74_RS08870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HJW74_RS08880	COG2925	Exonuclease
HJW74_RS08895	COG1289	transmembrane transporter activity
HJW74_RS08915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HJW74_RS08925	COG1942	4-Oxalocrotonate Tautomerase
HJW74_RS08930	COG0583	DNA-binding transcription factor activity
HJW74_RS08935	COG0095	Lipoate-protein ligase
HJW74_RS08940	COG0477	Major facilitator Superfamily
HJW74_RS08950	COG3300	MHYT domain
HJW74_RS08950	COG5001	Diguanylate cyclase
HJW74_RS08960	COG3615	Tellurite resistance protein tehB
HJW74_RS08985	COG3706	GGDEF domain
HJW74_RS09010	COG0534	Mate efflux family protein
HJW74_RS09020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HJW74_RS09040	COG0604	alcohol dehydrogenase
HJW74_RS09045	COG1309	transcriptional regulator
HJW74_RS09050	COG0025	NhaP-type Na H and K H
HJW74_RS09085	COG0251	oxidation-reduction process
HJW74_RS09105	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HJW74_RS09120	COG1418	mRNA catabolic process
HJW74_RS09125	COG0270	DNA (cytosine-5-)-methyltransferase activity
HJW74_RS09130	COG3727	T/G mismatch-specific endonuclease activity
HJW74_RS09135	COG0697	spore germination
HJW74_RS09140	COG2354	Protein conserved in bacteria
HJW74_RS09170	COG0366	Alpha amylase catalytic
HJW74_RS09195	COG2197	response regulator
HJW74_RS09205	COG2197	response regulator
HJW74_RS09240	COG3318	Belongs to the UPF0149 family
HJW74_RS09240	COG3012	SEC-C Motif Domain Protein
HJW74_RS09245	COG0814	amino acid
HJW74_RS09255	COG1528	Iron-storage protein
HJW74_RS09270	COG0477	Major facilitator Superfamily
HJW74_RS09280	COG2211	Major facilitator Superfamily
HJW74_RS09290	COG1528	Iron-storage protein
HJW74_RS09300	COG1879	ABC-type sugar transport system periplasmic component
HJW74_RS09310	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS09335	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HJW74_RS09345	COG3102	Protein conserved in bacteria
HJW74_RS09365	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HJW74_RS09370	COG1801	Protein of unknown function DUF72
HJW74_RS09375	COG1335	isochorismatase
HJW74_RS09385	COG0494	nUDIX hydrolase
HJW74_RS09410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HJW74_RS09420	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HJW74_RS09425	COG0739	heme binding
HJW74_RS09430	COG1560	Kdo2-lipid A biosynthetic process
HJW74_RS09440	COG1737	Transcriptional regulator
HJW74_RS09450	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HJW74_RS09455	COG0129	dihydroxy-acid dehydratase activity
HJW74_RS09460	COG0800	Aldolase
HJW74_RS09470	COG3141	response to X-ray
HJW74_RS09475	COG2979	Protein of unknown function (DUF533)
HJW74_RS09480	COG1770	oligopeptidase
HJW74_RS09485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HJW74_RS09495	COG2372	response to copper ion
HJW74_RS09500	COG1276	copper resistance
HJW74_RS09515	COG2990	Protein conserved in bacteria
HJW74_RS09540	COG3008	intermembrane lipid transfer
HJW74_RS09545	COG2995	paraquat-inducible protein a
HJW74_RS09550	COG1956	GAF domain-containing protein
HJW74_RS09570	COG2814	Major facilitator Superfamily
HJW74_RS09575	COG1414	Transcriptional regulator
HJW74_RS09610	COG0768	penicillin binding
HJW74_RS09615	COG2226	methyltransferase
HJW74_RS09630	COG3716	PTS system mannose fructose sorbose family IID component
HJW74_RS09635	COG3715	PTS system
HJW74_RS09640	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJW74_RS09640	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS09645	COG1253	flavin adenine dinucleotide binding
HJW74_RS09650	COG2200	EAL domain
HJW74_RS09660	COG1760	l-serine dehydratase
HJW74_RS09680	COG0251	oxidation-reduction process
HJW74_RS09685	COG1199	ATP-dependent helicase activity
HJW74_RS09695	COG3065	identical protein binding
HJW74_RS09705	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HJW74_RS09715	COG2894	cell division
HJW74_RS09730	COG0179	Fumarylacetoacetate (FAA) hydrolase
HJW74_RS09760	COG2719	SpoVR family
HJW74_RS09785	COG1619	proteins homologs of microcin C7 resistance protein MccF
HJW74_RS09795	COG4774	siderophore transport
HJW74_RS09810	COG2308	Evidence 4 Homologs of previously reported genes of
HJW74_RS09855	COG0583	DNA-binding transcription factor activity
HJW74_RS09860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HJW74_RS09875	COG1882	Formate acetyltransferase
HJW74_RS09910	COG0583	DNA-binding transcription factor activity
HJW74_RS09940	COG0583	DNA-binding transcription factor activity
HJW74_RS09955	COG3122	Protein conserved in bacteria
HJW74_RS09980	COG2885	chlorophyll binding
HJW74_RS09990	COG3501	Rhs element vgr protein
HJW74_RS09995	COG1388	LysM domain
HJW74_RS10060	COG0012	GTP binding
HJW74_RS10080	COG0659	secondary active sulfate transmembrane transporter activity
HJW74_RS10110	COG2890	protein-(glutamine-N5) methyltransferase activity
HJW74_RS10130	COG0387	Pfam Sodium calcium exchanger
HJW74_RS10135	COG4572	Cation transport regulator
HJW74_RS10140	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HJW74_RS10150	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HJW74_RS10155	COG3707	response regulator
HJW74_RS10165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HJW74_RS10175	COG1116	anion transmembrane transporter activity
HJW74_RS10180	COG2146	nitrite reductase [NAD(P)H] activity
HJW74_RS10180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HJW74_RS10185	COG0243	molybdopterin cofactor binding
HJW74_RS10190	COG4932	domain protein
HJW74_RS10195	COG2197	response regulator
HJW74_RS10200	COG3850	Histidine kinase
HJW74_RS10205	COG2223	nitrite transmembrane transporter activity
HJW74_RS10215	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HJW74_RS10220	COG1140	nitrate reductase beta subunit
HJW74_RS10225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HJW74_RS10230	COG2181	nitrate reductase activity
HJW74_RS10240	COG1522	sequence-specific DNA binding
HJW74_RS10275	COG0788	formyltetrahydrofolate deformylase activity
HJW74_RS10285	COG1752	Esterase of the alpha-beta hydrolase superfamily
HJW74_RS10290	COG0745	RESPONSE REGULATOR receiver
HJW74_RS10295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HJW74_RS10300	COG2916	Histone family protein nucleoid-structuring protein H-NS
HJW74_RS10310	COG1435	thymidine kinase activity
HJW74_RS10315	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS10315	COG1454	alcohol dehydrogenase
HJW74_RS10325	COG2095	MarC family integral membrane protein
HJW74_RS10335	COG4166	transmembrane transport
HJW74_RS10340	COG0601	transmembrane transport
HJW74_RS10345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HJW74_RS10350	COG0444	Belongs to the ABC transporter superfamily
HJW74_RS10360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HJW74_RS10380	COG2353	YceI-like domain
HJW74_RS10390	COG2350	Protein conserved in bacteria
HJW74_RS10400	COG3001	Fructosamine kinase
HJW74_RS10410	COG1105	Belongs to the carbohydrate kinase PfkB family
HJW74_RS10415	COG3137	Salt-induced outer membrane protein
HJW74_RS10455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HJW74_RS10455	COG0072	phenylalanine-tRNA ligase activity
HJW74_RS10475	COG0583	DNA-binding transcription factor activity
HJW74_RS10495	COG0386	Belongs to the glutathione peroxidase family
HJW74_RS10505	COG0791	NLP P60 protein
HJW74_RS10515	COG4256	Hemin uptake protein
HJW74_RS10520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HJW74_RS10535	COG0574	Belongs to the PEP-utilizing enzyme family
HJW74_RS10535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HJW74_RS10545	COG0628	permease
HJW74_RS10550	COG0277	FAD linked oxidase domain protein
HJW74_RS10550	COG0247	lactate metabolic process
HJW74_RS10555	COG2050	protein possibly involved in aromatic compounds catabolism
HJW74_RS10560	COG2261	transglycosylase associated protein
HJW74_RS10585	COG1120	ATPase activity
HJW74_RS10590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJW74_RS10600	COG0583	DNA-binding transcription factor activity
HJW74_RS10635	COG1304	FMN binding
HJW74_RS10640	COG1309	transcriptional regulator
HJW74_RS10660	COG0316	Belongs to the HesB IscA family
HJW74_RS10665	COG0719	Fe-S assembly protein
HJW74_RS10670	COG0396	ATPase activity
HJW74_RS10675	COG0719	Fe-S assembly protein
HJW74_RS10690	COG1376	ErfK ybiS ycfS ynhG family protein
HJW74_RS10720	COG1309	transcriptional regulator
HJW74_RS10730	COG2271	Major facilitator Superfamily
HJW74_RS10735	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HJW74_RS10760	COG1414	Transcriptional regulator
HJW74_RS10795	COG2814	Major facilitator Superfamily
HJW74_RS10815	COG0583	DNA-binding transcription factor activity
HJW74_RS10820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJW74_RS10840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HJW74_RS10845	COG1116	anion transmembrane transporter activity
HJW74_RS10850	COG4774	siderophore transport
HJW74_RS10855	COG1120	ATPase activity
HJW74_RS10860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJW74_RS10865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJW74_RS10885	COG0765	amino acid transport
HJW74_RS10890	COG1126	abc transporter atp-binding protein
HJW74_RS10930	COG3383	formate dehydrogenase (NAD+) activity
HJW74_RS10935	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HJW74_RS10950	COG1175	transmembrane transport
HJW74_RS10980	COG4133	protoheme IX ABC transporter activity
HJW74_RS10985	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HJW74_RS10990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HJW74_RS11005	COG1138	Cytochrome C-type biogenesis protein
HJW74_RS11010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HJW74_RS11015	COG3088	subunit of a heme lyase
HJW74_RS11015	COG4235	cytochrome complex assembly
HJW74_RS11040	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HJW74_RS11055	COG3850	Histidine kinase
HJW74_RS11055	COG5002	protein histidine kinase activity
HJW74_RS11060	COG0745	RESPONSE REGULATOR receiver
HJW74_RS11075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJW74_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS11110	COG2610	gluconate transmembrane transporter activity
HJW74_RS11115	COG1250	3-hydroxyacyl-CoA dehydrogenase
HJW74_RS11125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HJW74_RS11135	COG0583	DNA-binding transcription factor activity
HJW74_RS11160	COG0277	FAD linked oxidase domain protein
HJW74_RS11165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HJW74_RS11190	COG0402	S-adenosylhomocysteine deaminase activity
HJW74_RS11230	COG3321	synthase
HJW74_RS11230	COG0604	alcohol dehydrogenase
HJW74_RS11230	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS11260	COG4608	Belongs to the ABC transporter superfamily
HJW74_RS11265	COG0444	Belongs to the ABC transporter superfamily
HJW74_RS11290	COG0346	lactoylglutathione lyase activity
HJW74_RS11295	COG1349	DNA-binding transcription factor activity
HJW74_RS11335	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HJW74_RS11395	COG0307	riboflavin synthase, alpha
HJW74_RS11400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HJW74_RS11405	COG2814	Major facilitator Superfamily
HJW74_RS11410	COG0583	DNA-binding transcription factor activity
HJW74_RS11425	COG2814	Major facilitator Superfamily
HJW74_RS11440	COG0791	NLP P60 protein
HJW74_RS11445	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HJW74_RS11455	COG0346	lactoylglutathione lyase activity
HJW74_RS11460	COG1902	pentaerythritol trinitrate reductase activity
HJW74_RS11465	COG1309	transcriptional regulator
HJW74_RS11470	COG3313	Fe-S protein
HJW74_RS11475	COG4989	oxidoreductase activity
HJW74_RS11480	COG2032	superoxide dismutase activity
HJW74_RS11485	COG1289	transmembrane transporter activity
HJW74_RS11490	COG1566	PFAM secretion protein HlyD family protein
HJW74_RS11505	COG3706	GGDEF domain
HJW74_RS11520	COG3895	Periplasmic Protein
HJW74_RS11535	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HJW74_RS11540	COG0625	glutathione transferase activity
HJW74_RS11550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HJW74_RS11560	COG4659	FMN binding
HJW74_RS11595	COG2723	6-phospho-beta-galactosidase activity
HJW74_RS11605	COG0673	inositol 2-dehydrogenase activity
HJW74_RS11615	COG2814	Major facilitator Superfamily
HJW74_RS11635	COG3038	cytochrome b561
HJW74_RS11655	COG0583	DNA-binding transcription factor activity
HJW74_RS11660	COG3485	protocatechuate 3,4-dioxygenase
HJW74_RS11665	COG3485	protocatechuate 3,4-dioxygenase
HJW74_RS11670	COG5383	Protein conserved in bacteria
HJW74_RS11675	COG2272	Belongs to the type-B carboxylesterase lipase family
HJW74_RS11690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HJW74_RS11695	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HJW74_RS11700	COG1275	C4-dicarboxylate transporter malic acid transport protein
HJW74_RS11705	COG0500	methyltransferase
HJW74_RS11720	COG2207	Transcriptional regulator
HJW74_RS11720	COG3708	Transcriptional regulator
HJW74_RS11725	COG3135	benzoate transporter
HJW74_RS11730	COG1396	sequence-specific DNA binding
HJW74_RS11740	COG0826	peptidase U32
HJW74_RS11760	COG1294	oxidase, subunit
HJW74_RS11765	COG1271	oxidase subunit
HJW74_RS11770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HJW74_RS11775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HJW74_RS11780	COG3842	ATPase activity
HJW74_RS11785	COG1176	ABC-type spermidine putrescine transport system, permease component I
HJW74_RS11790	COG1177	transmembrane transport
HJW74_RS11795	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS11830	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS11840	COG0747	negative chemotaxis
HJW74_RS11850	COG3238	Protein conserved in bacteria
HJW74_RS11855	COG1247	-acetyltransferase
HJW74_RS11865	COG2130	NADP-dependent
HJW74_RS11880	COG3691	Protein conserved in bacteria
HJW74_RS11885	COG1228	amidohydrolase
HJW74_RS11890	COG4772	TonB-dependent receptor
HJW74_RS11915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HJW74_RS11920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJW74_RS11925	COG1473	amidohydrolase
HJW74_RS11930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJW74_RS11945	COG0765	amino acid transport
HJW74_RS11950	COG1126	abc transporter atp-binding protein
HJW74_RS11960	COG0625	glutathione transferase activity
HJW74_RS11990	COG2211	Major facilitator Superfamily
HJW74_RS12005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HJW74_RS12010	COG3842	ATPase activity
HJW74_RS12015	COG1840	ABC-type Fe3 transport system, periplasmic component
HJW74_RS12020	COG1178	ABC-type Fe3 transport system permease component
HJW74_RS12025	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HJW74_RS12030	COG2181	nitrate reductase activity
HJW74_RS12035	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HJW74_RS12040	COG1140	nitrate reductase beta subunit
HJW74_RS12045	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HJW74_RS12050	COG2223	nitrite transmembrane transporter activity
HJW74_RS12065	COG1414	Transcriptional regulator
HJW74_RS12070	COG4948	Mandelate Racemase Muconate Lactonizing
HJW74_RS12075	COG4829	muconolactone delta-isomerase
HJW74_RS12080	COG3485	protocatechuate 3,4-dioxygenase
HJW74_RS12090	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HJW74_RS12115	COG0437	4 iron, 4 sulfur cluster binding
HJW74_RS12120	COG2864	formate dehydrogenase
HJW74_RS12135	COG2326	polyphosphate kinase activity
HJW74_RS12145	COG2814	Major facilitator Superfamily
HJW74_RS12155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJW74_RS12175	COG0747	negative chemotaxis
HJW74_RS12180	COG1064	alcohol dehydrogenase
HJW74_RS12195	COG0488	(ABC) transporter
HJW74_RS12235	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS12240	COG3729	General stress protein
HJW74_RS12250	COG3685	Protein conserved in bacteria
HJW74_RS12260	COG0366	Alpha amylase catalytic
HJW74_RS12270	COG2323	membrane
HJW74_RS12280	COG3111	PFAM Bacterial OB fold (BOF) protein
HJW74_RS12290	COG1764	response to oxidative stress
HJW74_RS12315	COG3781	membrane
HJW74_RS12320	COG0243	molybdopterin cofactor binding
HJW74_RS12325	COG0583	DNA-binding transcription factor activity
HJW74_RS12330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS12355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS12360	COG1447	Phosphotransferase system cellobiose-specific component IIA
HJW74_RS12365	COG2814	Major facilitator Superfamily
HJW74_RS12370	COG1285	pathogenesis
HJW74_RS12375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HJW74_RS12385	COG0583	DNA-binding transcription factor activity
HJW74_RS12405	COG0519	Catalyzes the synthesis of GMP from XMP
HJW74_RS12405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HJW74_RS12445	COG0596	Alpha beta hydrolase
HJW74_RS12450	COG0745	RESPONSE REGULATOR receiver
HJW74_RS12455	COG2205	protein histidine kinase activity
HJW74_RS12470	COG0076	glutamate decarboxylase activity
HJW74_RS12475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HJW74_RS12480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HJW74_RS12485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HJW74_RS12490	COG1116	anion transmembrane transporter activity
HJW74_RS12495	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HJW74_RS12510	COG0673	inositol 2-dehydrogenase activity
HJW74_RS12520	COG1609	Transcriptional regulator
HJW74_RS12525	COG3706	GGDEF domain
HJW74_RS12530	COG0402	S-adenosylhomocysteine deaminase activity
HJW74_RS12535	COG1953	Uracil, thiamine, allantoin
HJW74_RS12570	COG0596	Alpha beta hydrolase
HJW74_RS12580	COG2207	Transcriptional regulator
HJW74_RS12605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HJW74_RS12625	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HJW74_RS12680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HJW74_RS12690	COG2070	2-Nitropropane dioxygenase
HJW74_RS12695	COG0583	DNA-binding transcription factor activity
HJW74_RS12705	COG1902	pentaerythritol trinitrate reductase activity
HJW74_RS12710	COG4529	Protein conserved in bacteria
HJW74_RS12715	COG0477	Major facilitator Superfamily
HJW74_RS12745	COG2223	nitrite transmembrane transporter activity
HJW74_RS12755	COG1609	Transcriptional regulator
HJW74_RS12760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS12770	COG3037	sugar-specific permease SgaT UlaA
HJW74_RS12775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HJW74_RS12785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJW74_RS12790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJW74_RS12790	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HJW74_RS12790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJW74_RS12805	COG0583	DNA-binding transcription factor activity
HJW74_RS12810	COG0583	DNA-binding transcription factor activity
HJW74_RS12815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HJW74_RS12825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HJW74_RS12840	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS12850	COG1609	Transcriptional regulator
HJW74_RS12880	COG1652	LysM domain
HJW74_RS12905	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HJW74_RS12905	COG0456	acetyltransferase
HJW74_RS12915	COG0667	Aldo Keto reductase
HJW74_RS12920	COG0667	Aldo Keto reductase
HJW74_RS12925	COG3386	PFAM SMP-30 Gluconolaconase
HJW74_RS12930	COG0667	Aldo Keto reductase
HJW74_RS12945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HJW74_RS12965	COG2723	6-phospho-beta-galactosidase activity
HJW74_RS12975	COG1349	DNA-binding transcription factor activity
HJW74_RS12990	COG1349	DNA-binding transcription factor activity
HJW74_RS12995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HJW74_RS13000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJW74_RS13005	COG0738	Major facilitator superfamily
HJW74_RS13050	COG1929	Belongs to the glycerate kinase type-1 family
HJW74_RS13055	COG3835	regulator
HJW74_RS13075	COG2186	Transcriptional regulator
HJW74_RS13080	COG1263	PTS System
HJW74_RS13080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJW74_RS13095	COG2814	Major facilitator Superfamily
HJW74_RS13100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS13100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS13120	COG2819	hydrolase of the alpha beta superfamily
HJW74_RS13125	COG5001	Diguanylate cyclase
HJW74_RS13125	COG3300	MHYT domain
HJW74_RS13160	COG3188	usher protein
HJW74_RS13175	COG3550	peptidyl-serine autophosphorylation
HJW74_RS13180	COG1396	sequence-specific DNA binding
HJW74_RS13185	COG2351	hydroxyisourate hydrolase activity
HJW74_RS13190	COG3195	allantoin biosynthetic process
HJW74_RS13190	COG3648	Uricase
HJW74_RS13195	COG2233	PERMEase
HJW74_RS13225	COG2207	Transcriptional regulator
HJW74_RS13240	COG4628	conserved protein (DUF2132)
HJW74_RS13260	COG2011	ABC-type metal ion transport system permease component
HJW74_RS13265	COG2070	2-Nitropropane dioxygenase
HJW74_RS13350	COG2199	diguanylate cyclase activity
HJW74_RS13365	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS13370	COG0583	DNA-binding transcription factor activity
HJW74_RS13380	COG0039	L-malate dehydrogenase activity
HJW74_RS13385	COG1349	DNA-binding transcription factor activity
HJW74_RS13390	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HJW74_RS13395	COG3395	kinase activity
HJW74_RS13405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HJW74_RS13410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HJW74_RS13415	COG2271	Major facilitator Superfamily
HJW74_RS13445	COG4977	sequence-specific DNA binding
HJW74_RS13455	COG0697	spore germination
HJW74_RS13460	COG2814	Major facilitator Superfamily
HJW74_RS13495	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HJW74_RS13535	COG2223	nitrite transmembrane transporter activity
HJW74_RS13540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HJW74_RS13555	COG1349	DNA-binding transcription factor activity
HJW74_RS13560	COG2084	Dehydrogenase
HJW74_RS13565	COG3395	kinase activity
HJW74_RS13570	COG0235	Class ii aldolase
HJW74_RS13575	COG3622	Belongs to the hyi family
HJW74_RS13580	COG2610	gluconate transmembrane transporter activity
HJW74_RS13585	COG2207	Transcriptional regulator
HJW74_RS13585	COG3708	Transcriptional regulator
HJW74_RS13600	COG2200	EAL domain
HJW74_RS13605	COG1546	Belongs to the CinA family
HJW74_RS13610	COG0071	Belongs to the small heat shock protein (HSP20) family
HJW74_RS13625	COG2197	response regulator
HJW74_RS13640	COG2135	peptidase activity
HJW74_RS13645	COG2207	Transcriptional regulator
HJW74_RS13660	COG4221	oxidoreductase activity
HJW74_RS13665	COG1802	Transcriptional regulator
HJW74_RS13670	COG0589	response to stress
HJW74_RS13675	COG0246	Mannitol dehydrogenase
HJW74_RS13680	COG2271	Major facilitator Superfamily
HJW74_RS13695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HJW74_RS13710	COG0243	molybdopterin cofactor binding
HJW74_RS13715	COG0437	4 iron, 4 sulfur cluster binding
HJW74_RS13720	COG3302	dmso reductase anchor subunit
HJW74_RS13735	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HJW74_RS13740	COG1940	carbohydrate kinase activity
HJW74_RS13745	COG0583	DNA-binding transcription factor activity
HJW74_RS13750	COG2814	Major facilitator Superfamily
HJW74_RS13755	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HJW74_RS13775	COG3591	Belongs to the peptidase S1B family
HJW74_RS13795	COG0628	permease
HJW74_RS13825	COG0679	Auxin Efflux Carrier
HJW74_RS13835	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HJW74_RS13860	COG3290	protein histidine kinase activity
HJW74_RS13865	COG4565	transcriptional regulatory protein
HJW74_RS13885	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HJW74_RS13885	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HJW74_RS13895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HJW74_RS13900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HJW74_RS13910	COG0183	Belongs to the thiolase family
HJW74_RS13915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HJW74_RS13925	COG1414	Transcriptional regulator
HJW74_RS13930	COG2840	Smr protein MutS2
HJW74_RS13935	COG0583	DNA-binding transcription factor activity
HJW74_RS13945	COG1473	amidohydrolase
HJW74_RS13950	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HJW74_RS13965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HJW74_RS13980	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HJW74_RS13985	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HJW74_RS14005	COG0531	amino acid
HJW74_RS14015	COG3136	membrane protein required for alginate biosynthesis
HJW74_RS14020	COG0745	RESPONSE REGULATOR receiver
HJW74_RS14030	COG2205	protein histidine kinase activity
HJW74_RS14040	COG0114	fumarate hydratase activity
HJW74_RS14045	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HJW74_RS14045	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HJW74_RS14050	COG1482	cell wall glycoprotein biosynthetic process
HJW74_RS14055	COG5339	Protein conserved in bacteria
HJW74_RS14060	COG1609	Transcriptional regulator
HJW74_RS14065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJW74_RS14065	COG1263	PTS System
HJW74_RS14070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HJW74_RS14095	COG2391	methyltransferase activity
HJW74_RS14100	COG0425	Belongs to the sulfur carrier protein TusA family
HJW74_RS14105	COG5562	phage envelope protein
HJW74_RS14110	COG0401	homolog of Blt101
HJW74_RS14115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HJW74_RS14120	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS14130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HJW74_RS14135	COG0477	Major facilitator Superfamily
HJW74_RS14140	COG1113	amino acid transport
HJW74_RS14145	COG2988	succinylglutamate desuccinylase activity
HJW74_RS14150	COG3724	N-succinylarginine dihydrolase activity
HJW74_RS14155	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS14160	COG3138	arginine N-succinyltransferase
HJW74_RS14165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HJW74_RS14180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HJW74_RS14185	COG0667	Aldo Keto reductase
HJW74_RS14190	COG0583	DNA-binding transcription factor activity
HJW74_RS14215	COG4122	O-methyltransferase activity
HJW74_RS14220	COG1643	Atp-dependent helicase
HJW74_RS14235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HJW74_RS14240	COG3327	negative regulation of DNA-templated transcription, initiation
HJW74_RS14245	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HJW74_RS14250	COG0183	Belongs to the thiolase family
HJW74_RS14255	COG2050	protein possibly involved in aromatic compounds catabolism
HJW74_RS14260	COG1250	3-hydroxyacyl-CoA dehydrogenase
HJW74_RS14265	COG1024	Enoyl-CoA hydratase
HJW74_RS14270	COG1024	Enoyl-CoA hydratase
HJW74_RS14275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HJW74_RS14280	COG2151	metal-sulfur cluster biosynthetic enzyme
HJW74_RS14285	COG3396	Phenylacetate-CoA oxygenase
HJW74_RS14290	COG3460	Phenylacetate-CoA oxygenase
HJW74_RS14295	COG3396	Phenylacetate-CoA oxygenase
HJW74_RS14300	COG2030	dehydratase
HJW74_RS14300	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS14320	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS14325	COG2207	Transcriptional regulator
HJW74_RS14330	COG3784	Protein of unknown function (DUF1318)
HJW74_RS14340	COG2911	Protein conserved in bacteria
HJW74_RS14345	COG0586	Pfam SNARE associated Golgi protein
HJW74_RS14350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HJW74_RS14355	COG3187	Heat shock protein
HJW74_RS14360	COG3042	response to heat
HJW74_RS14365	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HJW74_RS14365	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HJW74_RS14365	COG1013	pyruvate-flavodoxin oxidoreductase activity
HJW74_RS14365	COG0674	pyruvate-flavodoxin oxidoreductase activity
HJW74_RS14370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HJW74_RS14380	COG0589	response to stress
HJW74_RS14390	COG0513	Belongs to the DEAD box helicase family
HJW74_RS14400	COG1349	DNA-binding transcription factor activity
HJW74_RS14405	COG0673	inositol 2-dehydrogenase activity
HJW74_RS14420	COG1113	amino acid transport
HJW74_RS14425	COG1522	sequence-specific DNA binding
HJW74_RS14435	COG1448	Aminotransferase
HJW74_RS14440	COG2011	ABC-type metal ion transport system permease component
HJW74_RS14455	COG0436	Aminotransferase
HJW74_RS14460	COG0604	alcohol dehydrogenase
HJW74_RS14490	COG0583	DNA-binding transcription factor activity
HJW74_RS14510	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS14515	COG1309	transcriptional regulator
HJW74_RS14520	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS14640	COG2885	chlorophyll binding
HJW74_RS14670	COG0693	protein deglycase activity
HJW74_RS14675	COG1078	dGTPase activity
HJW74_RS14680	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS14685	COG0583	DNA-binding transcription factor activity
HJW74_RS14705	COG0656	L-ascorbic acid biosynthetic process
HJW74_RS14735	COG4166	transmembrane transport
HJW74_RS14745	COG2866	Carboxypeptidase
HJW74_RS14750	COG4948	Mandelate Racemase Muconate Lactonizing
HJW74_RS14755	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HJW74_RS14760	COG3180	Ammonia monooxygenase
HJW74_RS14775	COG0583	DNA-binding transcription factor activity
HJW74_RS14785	COG3106	COG3106 Predicted ATPase
HJW74_RS14795	COG1983	PspC domain protein
HJW74_RS14805	COG1842	Phage shock protein A
HJW74_RS14810	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HJW74_RS14820	COG1473	amidohydrolase
HJW74_RS14835	COG0702	epimerase
HJW74_RS14850	COG4171	peptide transport system, permease
HJW74_RS14865	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HJW74_RS14875	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HJW74_RS14880	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HJW74_RS14880	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HJW74_RS14895	COG1349	DNA-binding transcription factor activity
HJW74_RS14910	COG0023	Translation Initiation Factor
HJW74_RS14920	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HJW74_RS14925	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HJW74_RS14930	COG0671	phosphoesterase, PA-phosphatase related
HJW74_RS14940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HJW74_RS14965	COG0616	signal peptide processing
HJW74_RS14975	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS14980	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HJW74_RS14990	COG0583	DNA-binding transcription factor activity
HJW74_RS15000	COG0009	L-threonylcarbamoyladenylate synthase
HJW74_RS15010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HJW74_RS15015	COG0512	Glutamine amidotransferase of anthranilate synthase
HJW74_RS15015	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HJW74_RS15020	COG0135	phosphoribosylanthranilate isomerase activity
HJW74_RS15020	COG0134	indole-3-glycerol-phosphate synthase activity
HJW74_RS15055	COG4774	siderophore transport
HJW74_RS15065	COG3047	cAMP biosynthetic process
HJW74_RS15070	COG0727	PFAM Uncharacterised protein family (UPF0153)
HJW74_RS15100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HJW74_RS15105	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS15110	COG1988	membrane-bound metal-dependent
HJW74_RS15125	COG0753	catalase activity
HJW74_RS15135	COG1486	melibiose metabolic process
HJW74_RS15140	COG1917	Cupin 2, conserved barrel domain protein
HJW74_RS15140	COG2169	Transcriptional regulator
HJW74_RS15145	COG1447	Phosphotransferase system cellobiose-specific component IIA
HJW74_RS15150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS15160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS15165	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HJW74_RS15175	COG0322	excinuclease ABC activity
HJW74_RS15180	COG3678	ATP-independent chaperone mediated protein folding
HJW74_RS15190	COG3724	N-succinylarginine dihydrolase activity
HJW74_RS15200	COG3138	arginine N-succinyltransferase
HJW74_RS15210	COG0708	Exodeoxyribonuclease III
HJW74_RS15215	COG0398	Pfam SNARE associated Golgi protein
HJW74_RS15220	COG0398	Pfam SNARE associated Golgi protein
HJW74_RS15225	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HJW74_RS15230	COG4134	Bacterial extracellular solute-binding protein
HJW74_RS15235	COG4135	transport system, permease component
HJW74_RS15240	COG4136	ATPase activity
HJW74_RS15245	COG2897	thiosulfate sulfurtransferase activity
HJW74_RS15250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HJW74_RS15255	COG0494	nUDIX hydrolase
HJW74_RS15260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HJW74_RS15265	COG3321	synthase
HJW74_RS15265	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS15265	COG0604	alcohol dehydrogenase
HJW74_RS15270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HJW74_RS15275	COG0709	Synthesizes selenophosphate from selenide and ATP
HJW74_RS15290	COG0778	Nitroreductase
HJW74_RS15295	COG0616	signal peptide processing
HJW74_RS15300	COG0252	asparaginase activity
HJW74_RS15305	COG1335	isochorismatase
HJW74_RS15320	COG3139	Protein of unknown function (DUF1315)
HJW74_RS15340	COG0656	L-ascorbic acid biosynthetic process
HJW74_RS15345	COG3713	MltA-interacting MipA family protein
HJW74_RS15350	COG2766	serine protein kinase
HJW74_RS15365	COG0386	Belongs to the glutathione peroxidase family
HJW74_RS15390	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS15395	COG0583	DNA-binding transcription factor activity
HJW74_RS15400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HJW74_RS15405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HJW74_RS15410	COG3344	reverse transcriptase
HJW74_RS15420	COG0859	PFAM glycosyl transferase family 9
HJW74_RS15425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HJW74_RS15435	COG2207	Transcriptional regulator
HJW74_RS15440	COG2807	transmembrane transport
HJW74_RS15445	COG0504	CTP synthase activity
HJW74_RS15450	COG1683	Conserved Protein
HJW74_RS15455	COG3189	MarR family transcriptional regulator
HJW74_RS15460	COG3042	response to heat
HJW74_RS15465	COG2203	Gaf domain
HJW74_RS15465	COG2199	diguanylate cyclase activity
HJW74_RS15485	COG3182	Iron-regulated membrane protein
HJW74_RS15495	COG1560	Kdo2-lipid A biosynthetic process
HJW74_RS15510	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HJW74_RS15515	COG3706	GGDEF domain
HJW74_RS15520	COG0583	DNA-binding transcription factor activity
HJW74_RS15525	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HJW74_RS15555	COG1294	oxidase, subunit
HJW74_RS15560	COG1271	oxidase subunit
HJW74_RS15565	COG3546	catalase activity
HJW74_RS15570	COG3685	Protein conserved in bacteria
HJW74_RS15575	COG3685	Protein conserved in bacteria
HJW74_RS15580	COG3729	General stress protein
HJW74_RS15585	COG1063	alcohol dehydrogenase
HJW74_RS15590	COG3813	Protein conserved in bacteria
HJW74_RS15610	COG0640	Transcriptional regulator
HJW74_RS15615	COG0538	isocitrate dehydrogenase activity
HJW74_RS15620	COG1187	pseudouridine synthase activity
HJW74_RS15640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HJW74_RS15660	COG2205	protein histidine kinase activity
HJW74_RS15665	COG2850	peptidyl-arginine hydroxylation
HJW74_RS15685	COG1177	transmembrane transport
HJW74_RS15700	COG0318	PFAM AMP-dependent synthetase and ligase
HJW74_RS15705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HJW74_RS15710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HJW74_RS15715	COG0698	ribose 5-phosphate isomerase
HJW74_RS15730	COG3395	kinase activity
HJW74_RS15745	COG2390	Transcriptional regulator
HJW74_RS15755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HJW74_RS15765	COG4591	ABC-type transport system involved in lipoprotein release permease component
HJW74_RS15775	COG4591	ABC-type transport system involved in lipoprotein release permease component
HJW74_RS15785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HJW74_RS15790	COG1388	LysM domain
HJW74_RS15790	COG1376	ErfK ybiS ycfS ynhG family protein
HJW74_RS15805	COG1309	transcriptional regulator
HJW74_RS15820	COG3134	Outer membrane lipoprotein
HJW74_RS15825	COG1252	NADH dehydrogenase
HJW74_RS15850	COG5633	Lipoprotein
HJW74_RS15855	COG0537	adenosine 5'-monophosphoramidase activity
HJW74_RS15865	COG0084	hydrolase, TatD family'
HJW74_RS15870	COG0470	DNA polymerase III
HJW74_RS15880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HJW74_RS15885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HJW74_RS15890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HJW74_RS15905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HJW74_RS15925	COG1399	metal-binding, possibly nucleic acid-binding protein
HJW74_RS15945	COG1530	ribonuclease E activity
HJW74_RS15950	COG0583	DNA-binding transcription factor activity
HJW74_RS15955	COG2814	Major facilitator Superfamily
HJW74_RS15975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HJW74_RS16025	COG1560	Kdo2-lipid A biosynthetic process
HJW74_RS16040	COG5645	(Lipo)protein
HJW74_RS16075	COG3381	protein complex oligomerization
HJW74_RS16105	COG1309	transcriptional regulator
HJW74_RS16110	COG0583	DNA-binding transcription factor activity
HJW74_RS16120	COG1335	isochorismatase
HJW74_RS16135	COG1702	phosphate starvation-inducible protein PhoH
HJW74_RS16155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HJW74_RS16170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HJW74_RS16185	COG1309	transcriptional regulator
HJW74_RS16220	COG2233	PERMEase
HJW74_RS16230	COG3729	General stress protein
HJW74_RS16260	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS16275	COG0531	amino acid
HJW74_RS16280	COG0174	glutamine synthetase
HJW74_RS16285	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HJW74_RS16290	COG1917	Cupin 2, conserved barrel domain protein
HJW74_RS16290	COG1396	sequence-specific DNA binding
HJW74_RS16295	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS16300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HJW74_RS16305	COG0583	DNA-binding transcription factor activity
HJW74_RS16310	COG0473	3-isopropylmalate dehydrogenase activity
HJW74_RS16315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HJW74_RS16320	COG4638	Rieske (2fe-2S)
HJW74_RS16325	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS16330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HJW74_RS16355	COG0670	Belongs to the BI1 family
HJW74_RS16370	COG2207	Transcriptional regulator
HJW74_RS16375	COG1881	PFAM PEBP family protein
HJW74_RS16400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJW74_RS16405	COG2274	protein secretion by the type I secretion system
HJW74_RS16445	COG1832	CoA-binding protein
HJW74_RS16455	COG0210	DNA helicase
HJW74_RS16460	COG3304	Inner membrane component domain
HJW74_RS16465	COG1289	transmembrane transporter activity
HJW74_RS16470	COG3070	regulator of competence-specific genes
HJW74_RS16490	COG1067	ATP-dependent peptidase activity
HJW74_RS16500	COG3130	regulation of translation
HJW74_RS16505	COG3009	Protein conserved in bacteria
HJW74_RS16510	COG3008	intermembrane lipid transfer
HJW74_RS16510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HJW74_RS16515	COG2995	paraquat-inducible protein a
HJW74_RS16520	COG0488	(ABC) transporter
HJW74_RS16530	COG0633	Ferredoxin
HJW74_RS16530	COG3217	Mosc domain protein beta barrel domain protein
HJW74_RS16545	COG0431	NADPH-dependent FMN reductase
HJW74_RS16550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HJW74_RS16555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJW74_RS16560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HJW74_RS16570	COG0308	aminopeptidase N
HJW74_RS16580	COG1473	amidohydrolase
HJW74_RS16590	COG0814	amino acid
HJW74_RS16610	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HJW74_RS16615	COG1448	Aminotransferase
HJW74_RS16620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HJW74_RS16625	COG3108	Peptidase M15
HJW74_RS16630	COG2989	Protein conserved in bacteria
HJW74_RS16640	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HJW74_RS16650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HJW74_RS16655	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HJW74_RS16660	COG3173	Aminoglycoside phosphotransferase
HJW74_RS16675	COG3214	Protein conserved in bacteria
HJW74_RS16690	COG2333	competence protein COMEC
HJW74_RS16690	COG0658	competence protein
HJW74_RS16700	COG0539	negative regulation of cytoplasmic translation
HJW74_RS16720	COG2323	membrane
HJW74_RS16725	COG1944	ATP diphosphatase activity
HJW74_RS16730	COG2116	formate transmembrane transporter activity
HJW74_RS16735	COG1882	Formate acetyltransferase
HJW74_RS16740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HJW74_RS16745	COG0477	Major facilitator Superfamily
HJW74_RS16755	COG3302	dmso reductase anchor subunit
HJW74_RS16760	COG0437	4 iron, 4 sulfur cluster binding
HJW74_RS16765	COG0243	molybdopterin cofactor binding
HJW74_RS16775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HJW74_RS16785	COG1674	ftsk spoiiie
HJW74_RS16785	COG1178	ABC-type Fe3 transport system permease component
HJW74_RS16800	COG0492	ferredoxin-NADP+ reductase activity
HJW74_RS16805	COG4988	ABC transporter
HJW74_RS16810	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HJW74_RS16825	COG0542	response to heat
HJW74_RS16835	COG1278	Cold shock
HJW74_RS16845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJW74_RS16850	COG3593	DNA synthesis involved in DNA repair
HJW74_RS16860	COG2431	L-lysine efflux transmembrane transporter activity
HJW74_RS16870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HJW74_RS16880	COG0028	Belongs to the TPP enzyme family
HJW74_RS16885	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HJW74_RS16890	COG0702	epimerase
HJW74_RS16895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HJW74_RS16900	COG3023	N-Acetylmuramoyl-L-alanine amidase
HJW74_RS16905	COG2203	Gaf domain
HJW74_RS16905	COG3706	GGDEF domain
HJW74_RS16905	COG4251	negative regulation of phosphorylation
HJW74_RS16905	COG5001	Diguanylate cyclase
HJW74_RS16915	COG1126	abc transporter atp-binding protein
HJW74_RS16920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJW74_RS16925	COG4215	(ABC) transporter
HJW74_RS16930	COG4160	amino acid transport
HJW74_RS16935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJW74_RS16940	COG5002	protein histidine kinase activity
HJW74_RS16945	COG0745	RESPONSE REGULATOR receiver
HJW74_RS16960	COG1177	transmembrane transport
HJW74_RS16965	COG1176	ABC-type spermidine putrescine transport system, permease component I
HJW74_RS16970	COG3842	ATPase activity
HJW74_RS16975	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HJW74_RS16990	COG0778	Nitroreductase
HJW74_RS17020	COG3226	Transcriptional regulator
HJW74_RS17025	COG0738	Major facilitator superfamily
HJW74_RS17030	COG0561	phosphatase activity
HJW74_RS17035	COG2814	Major facilitator Superfamily
HJW74_RS17040	COG0671	phosphoesterase, PA-phosphatase related
HJW74_RS17045	COG1349	DNA-binding transcription factor activity
HJW74_RS17050	COG1686	Belongs to the peptidase S11 family
HJW74_RS17060	COG0625	glutathione transferase activity
HJW74_RS17065	COG2133	pyrroloquinoline quinone binding
HJW74_RS17075	COG2223	nitrite transmembrane transporter activity
HJW74_RS17095	COG0747	negative chemotaxis
HJW74_RS17110	COG0303	'Molybdopterin
HJW74_RS17115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HJW74_RS17120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HJW74_RS17125	COG1882	Formate acetyltransferase
HJW74_RS17130	COG0561	phosphatase activity
HJW74_RS17140	COG1609	Transcriptional regulator
HJW74_RS17145	COG2271	Major facilitator Superfamily
HJW74_RS17155	COG0488	(ABC) transporter
HJW74_RS17160	COG2365	Tyrosine phosphatase family
HJW74_RS17165	COG1376	ErfK ybiS ycfS ynhG family protein
HJW74_RS17170	COG2188	Transcriptional regulator
HJW74_RS17175	COG2723	6-phospho-beta-galactosidase activity
HJW74_RS17180	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HJW74_RS17195	COG2194	sulfuric ester hydrolase activity
HJW74_RS17200	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HJW74_RS17220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJW74_RS17225	COG0765	amino acid transport
HJW74_RS17230	COG1126	abc transporter atp-binding protein
HJW74_RS17235	COG0668	transmembrane transport
HJW74_RS17245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HJW74_RS17255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HJW74_RS17265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HJW74_RS17270	COG1199	ATP-dependent helicase activity
HJW74_RS17275	COG0513	Belongs to the DEAD box helicase family
HJW74_RS17280	COG3958	Transketolase
HJW74_RS17285	COG3959	Transketolase, thiamine diphosphate binding domain
HJW74_RS17290	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS17295	COG2271	Major facilitator Superfamily
HJW74_RS17305	COG0583	DNA-binding transcription factor activity
HJW74_RS17310	COG1309	transcriptional regulator
HJW74_RS17315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJW74_RS17320	COG1131	(ABC) transporter
HJW74_RS17325	COG0842	Transport permease protein
HJW74_RS17330	COG0842	Transport permease protein
HJW74_RS17340	COG3568	Endonuclease Exonuclease Phosphatase
HJW74_RS17345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HJW74_RS17350	COG0392	lysyltransferase activity
HJW74_RS17355	COG0670	Belongs to the BI1 family
HJW74_RS17360	COG0314	molybdopterin synthase activity
HJW74_RS17365	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HJW74_RS17375	COG0521	Mo-molybdopterin cofactor biosynthetic process
HJW74_RS17395	COG0745	RESPONSE REGULATOR receiver
HJW74_RS17400	COG0642	Histidine kinase
HJW74_RS17425	COG2226	methyltransferase
HJW74_RS17440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HJW74_RS17445	COG1881	PFAM PEBP family protein
HJW74_RS17485	COG4677	pectinesterase activity
HJW74_RS17500	COG0589	response to stress
HJW74_RS17505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJW74_RS17540	COG0789	Transcriptional regulator
HJW74_RS17545	COG2200	EAL domain
HJW74_RS17570	COG0561	phosphatase activity
HJW74_RS17580	COG4149	molybdate abc transporter
HJW74_RS17585	COG0725	ABC transporter, periplasmic molybdate-binding protein
HJW74_RS17595	COG2005	Transcriptional regulator
HJW74_RS17595	COG3585	molybdate ion transport
HJW74_RS17605	COG1119	ATPase activity
HJW74_RS17615	COG1085	galactose-1-phosphate uridylyltransferase
HJW74_RS17625	COG2017	converts alpha-aldose to the beta-anomer
HJW74_RS17655	COG0471	metal ion transport
HJW74_RS17655	COG0490	domain, Protein
HJW74_RS17660	COG0583	DNA-binding transcription factor activity
HJW74_RS17675	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HJW74_RS17675	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HJW74_RS17680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HJW74_RS17695	COG3201	nicotinamide mononucleotide transporter
HJW74_RS17700	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HJW74_RS17745	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HJW74_RS17750	COG2885	chlorophyll binding
HJW74_RS17760	COG3064	Membrane
HJW74_RS17760	COG3064	Membrane
HJW74_RS17765	COG0848	biopolymer transport protein
HJW74_RS17770	COG0811	peptide transport
HJW74_RS17775	COG0824	Thioesterase
HJW74_RS17780	COG3790	cyd operon protein YbgE
HJW74_RS17785	COG4890	Cyd operon protein YbgT
HJW74_RS17790	COG1294	oxidase, subunit
HJW74_RS17795	COG1271	oxidase subunit
HJW74_RS17805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HJW74_RS17815	COG0508	dehydrogenase complex catalyzes the overall conversion of
HJW74_RS17820	COG0567	Dehydrogenase, E1 component
HJW74_RS17825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HJW74_RS17830	COG1053	succinate dehydrogenase
HJW74_RS17835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HJW74_RS17840	COG2009	succinate dehydrogenase
HJW74_RS17875	COG1984	allophanate hydrolase subunit 2
HJW74_RS17880	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HJW74_RS17895	COG0415	Belongs to the DNA photolyase family
HJW74_RS17925	COG2205	protein histidine kinase activity
HJW74_RS17930	COG0745	RESPONSE REGULATOR receiver
HJW74_RS17940	COG0033	Phosphoglucomutase
HJW74_RS17950	COG0596	Alpha beta hydrolase
HJW74_RS17965	COG0735	belongs to the Fur family
HJW74_RS18005	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HJW74_RS18010	COG1846	Transcriptional regulator
HJW74_RS18010	COG1940	carbohydrate kinase activity
HJW74_RS18015	COG0647	UMP catabolic process
HJW74_RS18020	COG0367	asparagine synthase
HJW74_RS18060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HJW74_RS18070	COG1702	phosphate starvation-inducible protein PhoH
HJW74_RS18095	COG0765	amino acid transport
HJW74_RS18100	COG0765	amino acid transport
HJW74_RS18105	COG1126	abc transporter atp-binding protein
HJW74_RS18120	COG2888	peptidyl-tyrosine sulfation
HJW74_RS18135	COG1466	dna polymerase III delta subunit
HJW74_RS18150	COG0799	negative regulation of ribosome biogenesis
HJW74_RS18160	COG0768	penicillin binding
HJW74_RS18165	COG0772	Belongs to the SEDS family
HJW74_RS18170	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HJW74_RS18175	COG1686	Belongs to the peptidase S11 family
HJW74_RS18190	COG0583	DNA-binding transcription factor activity
HJW74_RS18205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HJW74_RS18225	COG3069	C4-dicarboxylate transmembrane transporter activity
HJW74_RS18230	COG3719	Belongs to the RNase T2 family
HJW74_RS18235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HJW74_RS18255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HJW74_RS18260	COG0583	DNA-binding transcription factor activity
HJW74_RS18265	COG3969	phosphoadenosine phosphosulfate
HJW74_RS18270	COG1475	DNA binding
HJW74_RS18275	COG0436	Aminotransferase
HJW74_RS18300	COG1129	ABC transporter
HJW74_RS18305	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS18310	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS18320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HJW74_RS18335	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HJW74_RS18345	COG0402	S-adenosylhomocysteine deaminase activity
HJW74_RS18355	COG0483	inositol monophosphate 1-phosphatase activity
HJW74_RS18360	COG2271	Major facilitator Superfamily
HJW74_RS18395	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS18400	COG1129	ABC transporter
HJW74_RS18405	COG0371	Dehydrogenase
HJW74_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS18425	COG2879	small protein
HJW74_RS18430	COG1966	Carbon starvation protein
HJW74_RS18440	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS18445	COG3433	isochorismatase activity
HJW74_RS18445	COG1535	isochorismatase
HJW74_RS18450	COG1021	2,3-dihydroxybenzoate-AMP ligase
HJW74_RS18455	COG1169	isochorismate synthase
HJW74_RS18460	COG4592	Periplasmic binding protein
HJW74_RS18470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJW74_RS18475	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJW74_RS18480	COG1120	ATPase activity
HJW74_RS18485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HJW74_RS18485	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HJW74_RS18490	COG3251	PFAM MbtH domain protein
HJW74_RS18495	COG2382	esterase
HJW74_RS18500	COG4771	TonB-dependent receptor
HJW74_RS18505	COG2977	Belongs to the P-Pant transferase superfamily
HJW74_RS18510	COG3958	Transketolase
HJW74_RS18515	COG3959	Transketolase, thiamine diphosphate binding domain
HJW74_RS18520	COG2390	Transcriptional regulator
HJW74_RS18525	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HJW74_RS18530	COG1879	ABC-type sugar transport system periplasmic component
HJW74_RS18540	COG1129	ABC transporter
HJW74_RS18545	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS18555	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS18565	COG0583	DNA-binding transcription factor activity
HJW74_RS18570	COG0668	transmembrane transport
HJW74_RS18580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HJW74_RS18605	COG0747	negative chemotaxis
HJW74_RS18610	COG0601	transmembrane transport
HJW74_RS18615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HJW74_RS18620	COG0444	Belongs to the ABC transporter superfamily
HJW74_RS18625	COG4608	Belongs to the ABC transporter superfamily
HJW74_RS18635	COG4221	oxidoreductase activity
HJW74_RS18645	COG4215	(ABC) transporter
HJW74_RS18655	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HJW74_RS18670	COG0697	spore germination
HJW74_RS18680	COG3698	Phosphodiester glycosidase
HJW74_RS18725	COG2315	Protein conserved in bacteria
HJW74_RS18730	COG0778	Nitroreductase
HJW74_RS18740	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJW74_RS18750	COG3716	PTS system mannose fructose sorbose family IID component
HJW74_RS18755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HJW74_RS18760	COG2222	sugar isomerase
HJW74_RS18765	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HJW74_RS18765	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HJW74_RS18780	COG0477	Major facilitator Superfamily
HJW74_RS18785	COG0668	transmembrane transport
HJW74_RS18800	COG0673	inositol 2-dehydrogenase activity
HJW74_RS18810	COG2211	Major facilitator Superfamily
HJW74_RS18815	COG1113	amino acid transport
HJW74_RS18830	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS18835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HJW74_RS18845	COG0531	amino acid
HJW74_RS18860	COG4680	protein conserved in bacteria
HJW74_RS18900	COG0667	Aldo Keto reductase
HJW74_RS18905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJW74_RS18910	COG1473	amidohydrolase
HJW74_RS18945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJW74_RS18950	COG1120	ATPase activity
HJW74_RS18955	COG1566	PFAM secretion protein HlyD family protein
HJW74_RS19010	COG4211	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS19015	COG1129	ABC transporter
HJW74_RS19030	COG0673	inositol 2-dehydrogenase activity
HJW74_RS19060	COG3104	oligopeptide transport
HJW74_RS19065	COG1982	Orn Lys Arg decarboxylase major
HJW74_RS19070	COG0531	amino acid
HJW74_RS19075	COG3710	Transcriptional regulator
HJW74_RS19085	COG1560	Kdo2-lipid A biosynthetic process
HJW74_RS19100	COG3188	usher protein
HJW74_RS19105	COG3121	Chaperone
HJW74_RS19110	COG3539	Fimbrial protein
HJW74_RS19165	COG2501	S4 domain
HJW74_RS19175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HJW74_RS19190	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HJW74_RS19195	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HJW74_RS19215	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HJW74_RS19220	COG4181	ATPase activity
HJW74_RS19225	COG2755	lipolytic protein G-D-S-L family
HJW74_RS19230	COG0300	oxidoreductase activity
HJW74_RS19235	COG3118	belongs to the thioredoxin family
HJW74_RS19240	COG0390	transport system, permease component
HJW74_RS19245	COG4619	ABC transporter
HJW74_RS19250	COG0330	HflC and HflK could
HJW74_RS19255	COG1585	Membrane protein implicated in regulation of membrane protease activity
HJW74_RS19270	COG3735	TraB family
HJW74_RS19275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HJW74_RS19285	COG2223	nitrite transmembrane transporter activity
HJW74_RS19300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HJW74_RS19300	COG4651	solute:proton antiporter activity
HJW74_RS19305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJW74_RS19345	COG2832	Protein of unknown function (DUF454)
HJW74_RS19350	COG3923	Primosomal replication protein n
HJW74_RS19360	COG5464	transposase or invertase
HJW74_RS19365	COG1196	nuclear chromosome segregation
HJW74_RS19365	COG3264	Mechanosensitive ion channel
HJW74_RS19370	COG1309	transcriptional regulator
HJW74_RS19375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJW74_RS19380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJW74_RS19395	COG0110	maltose O-acetyltransferase activity
HJW74_RS19445	COG1874	Beta-galactosidase
HJW74_RS19450	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HJW74_RS19455	COG3833	ABC-type maltose transport systems, permease component
HJW74_RS19460	COG1175	transmembrane transport
HJW74_RS19465	COG2182	Extracellular solute-binding protein
HJW74_RS19480	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HJW74_RS19495	COG2364	Membrane
HJW74_RS19525	COG3695	enzyme binding
HJW74_RS19530	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HJW74_RS19535	COG1946	Acyl-CoA thioesterase
HJW74_RS19540	COG0004	ammonium transporteR
HJW74_RS19545	COG0347	Belongs to the P(II) protein family
HJW74_RS19550	COG1132	(ABC) transporter
HJW74_RS19555	COG1132	(ABC) transporter
HJW74_RS19560	COG1522	sequence-specific DNA binding
HJW74_RS19575	COG4533	DNA binding
HJW74_RS19585	COG0824	Thioesterase
HJW74_RS19590	COG1555	photosystem II stabilization
HJW74_RS19595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HJW74_RS19600	COG0776	regulation of translation
HJW74_RS19605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HJW74_RS19630	COG0271	Belongs to the BolA IbaG family
HJW74_RS19635	COG3056	Lipoprotein
HJW74_RS19640	COG2223	nitrite transmembrane transporter activity
HJW74_RS19645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HJW74_RS19650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HJW74_RS19655	COG1845	cytochrome c oxidase, subunit III
HJW74_RS19660	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HJW74_RS19675	COG1414	Transcriptional regulator
HJW74_RS19680	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HJW74_RS19685	COG1053	succinate dehydrogenase
HJW74_RS19695	COG1053	succinate dehydrogenase
HJW74_RS19710	COG0673	inositol 2-dehydrogenase activity
HJW74_RS19715	COG2814	Major facilitator Superfamily
HJW74_RS19725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HJW74_RS19730	COG0693	protein deglycase activity
HJW74_RS19750	COG0142	geranyltranstransferase activity
HJW74_RS19760	COG0667	Aldo Keto reductase
HJW74_RS19765	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HJW74_RS19785	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HJW74_RS19785	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HJW74_RS19795	COG4238	major outer membrane lipoprotein
HJW74_RS19815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HJW74_RS19820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HJW74_RS19825	COG1862	Preprotein translocase
HJW74_RS19850	COG0450	alkyl hydroperoxide reductase
HJW74_RS19860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS19875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJW74_RS19885	COG1228	amidohydrolase
HJW74_RS19895	COG1335	isochorismatase
HJW74_RS19900	COG0583	DNA-binding transcription factor activity
HJW74_RS19905	COG0366	Alpha amylase catalytic
HJW74_RS19930	COG0420	3'-5' exonuclease activity
HJW74_RS19935	COG0419	ATPase involved in DNA repair
HJW74_RS19940	COG1940	carbohydrate kinase activity
HJW74_RS19955	COG4126	flavin adenine dinucleotide binding
HJW74_RS19965	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HJW74_RS19970	COG3416	Protein conserved in bacteria
HJW74_RS19980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HJW74_RS19990	COG1785	Belongs to the alkaline phosphatase family
HJW74_RS20030	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HJW74_RS20035	COG1335	isochorismatase
HJW74_RS20040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HJW74_RS20045	COG0113	porphobilinogen synthase activity
HJW74_RS20055	COG2175	clavaminate synthase activity
HJW74_RS20060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HJW74_RS20065	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HJW74_RS20070	COG4521	taurine ABC transporter
HJW74_RS20075	COG2040	homocysteine
HJW74_RS20080	COG0833	amino acid
HJW74_RS20095	COG4303	Ethanolamine ammonia lyase large subunit
HJW74_RS20100	COG4302	ethanolamine ammonia-lyase activity
HJW74_RS20140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJW74_RS20145	COG1126	abc transporter atp-binding protein
HJW74_RS20150	COG4597	amino acid ABC transporter
HJW74_RS20155	COG0765	amino acid transport
HJW74_RS20170	COG3188	usher protein
HJW74_RS20195	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HJW74_RS20205	COG3639	organic phosphonate transmembrane transporter activity
HJW74_RS20230	COG0791	NLP P60 protein
HJW74_RS20255	COG0582	viral genome integration into host DNA
HJW74_RS20290	COG3121	Chaperone
HJW74_RS20295	COG3188	usher protein
HJW74_RS20325	COG2909	trisaccharide binding
HJW74_RS20330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HJW74_RS20335	COG0022	dehydrogenase e1 component
HJW74_RS20340	COG0508	dehydrogenase complex catalyzes the overall conversion of
HJW74_RS20345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HJW74_RS20365	COG1070	Carbohydrate kinase
HJW74_RS20370	COG1028	Short-chain dehydrogenase reductase Sdr
HJW74_RS20375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HJW74_RS20380	COG3775	system Galactitol-specific IIC component
HJW74_RS20385	COG0625	glutathione transferase activity
HJW74_RS20390	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HJW74_RS20405	COG0579	oxidoreductase
HJW74_RS20410	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS20415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HJW74_RS20420	COG1113	amino acid transport
HJW74_RS20425	COG1802	Transcriptional regulator
HJW74_RS20430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HJW74_RS20440	COG1596	polysaccharide export
HJW74_RS20460	COG0463	Glycosyl transferase, family 2
HJW74_RS20465	COG0438	transferase activity, transferring glycosyl groups
HJW74_RS20470	COG0297	glycogen (starch) synthase activity
HJW74_RS20470	COG0438	transferase activity, transferring glycosyl groups
HJW74_RS20485	COG1045	serine acetyltransferase
HJW74_RS20505	COG2195	Cleaves the N-terminal amino acid of tripeptides
HJW74_RS20510	COG0454	-acetyltransferase
HJW74_RS20525	COG2991	Protein conserved in bacteria
HJW74_RS20540	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HJW74_RS20545	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HJW74_RS20560	COG3034	peptidoglycan biosynthetic process
HJW74_RS20565	COG0121	glutamine amidotransferase
HJW74_RS20575	COG1960	acyl-CoA dehydrogenase activity
HJW74_RS20580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HJW74_RS20590	COG0583	DNA-binding transcription factor activity
HJW74_RS20600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HJW74_RS20610	COG2226	methyltransferase
HJW74_RS20620	COG0741	lytic transglycosylase activity
HJW74_RS20620	COG1388	LysM domain
HJW74_RS20625	COG2226	methyltransferase
HJW74_RS20635	COG2814	Major facilitator Superfamily
HJW74_RS20640	COG0583	DNA-binding transcription factor activity
HJW74_RS20645	COG0656	L-ascorbic acid biosynthetic process
HJW74_RS20680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HJW74_RS20690	COG2011	ABC-type metal ion transport system permease component
HJW74_RS20695	COG1464	Belongs to the NlpA lipoprotein family
HJW74_RS20705	COG1720	tRNA m6t6A37 methyltransferase activity
HJW74_RS20715	COG0791	NLP P60 protein
HJW74_RS20720	COG3015	lipoprotein NlpE involved in copper resistance
HJW74_RS20725	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HJW74_RS20740	COG4568	rho-dependent transcription termination
HJW74_RS20750	COG0346	lactoylglutathione lyase activity
HJW74_RS20765	COG0587	DNA-directed DNA polymerase activity
HJW74_RS20795	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HJW74_RS20805	COG0750	zinc metalloprotease
HJW74_RS20810	COG0575	Belongs to the CDS family
HJW74_RS20820	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HJW74_RS20845	COG0024	Methionine aminopeptidase
HJW74_RS20850	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HJW74_RS20865	COG3835	regulator
HJW74_RS20870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HJW74_RS20890	COG2860	membrane
HJW74_RS20910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJW74_RS20915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HJW74_RS20920	COG1120	ATPase activity
HJW74_RS20925	COG4774	siderophore transport
HJW74_RS20930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HJW74_RS21025	COG1643	Atp-dependent helicase
HJW74_RS21030	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HJW74_RS21050	COG0617	tRNA 3'-terminal CCA addition
HJW74_RS21055	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HJW74_RS21075	COG0726	polysaccharide deacetylase
HJW74_RS21080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS21085	COG0842	Transport permease protein
HJW74_RS21090	COG1131	(ABC) transporter
HJW74_RS21095	COG0288	reversible hydration of carbon dioxide
HJW74_RS21110	COG4993	Dehydrogenase
HJW74_RS21115	COG2132	Multicopper oxidase
HJW74_RS21165	COG3064	Membrane
HJW74_RS21180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HJW74_RS21185	COG0508	dehydrogenase complex catalyzes the overall conversion of
HJW74_RS21190	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HJW74_RS21195	COG2186	Transcriptional regulator
HJW74_RS21200	COG1113	amino acid transport
HJW74_RS21205	COG2211	Major facilitator Superfamily
HJW74_RS21210	COG3940	Belongs to the glycosyl hydrolase 43 family
HJW74_RS21215	COG3725	Membrane protein required for beta-lactamase induction
HJW74_RS21220	COG3023	N-Acetylmuramoyl-L-alanine amidase
HJW74_RS21230	COG4969	Belongs to the N-Me-Phe pilin family
HJW74_RS21235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HJW74_RS21240	COG1459	type II secretion system
HJW74_RS21265	COG0494	nUDIX hydrolase
HJW74_RS21285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HJW74_RS21290	COG0849	cell division
HJW74_RS21315	COG0772	Belongs to the SEDS family
HJW74_RS21330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HJW74_RS21335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HJW74_RS21340	COG0768	penicillin binding
HJW74_RS21360	COG1609	Transcriptional regulator
HJW74_RS21370	COG0028	Belongs to the TPP enzyme family
HJW74_RS21420	COG0738	Major facilitator superfamily
HJW74_RS21430	COG0583	DNA-binding transcription factor activity
HJW74_RS21435	COG2271	Major facilitator Superfamily
HJW74_RS21440	COG2814	Major facilitator Superfamily
HJW74_RS21465	COG1178	ABC-type Fe3 transport system permease component
HJW74_RS21475	COG0586	Pfam SNARE associated Golgi protein
HJW74_RS21500	COG0235	Class ii aldolase
HJW74_RS21505	COG0417	DNA replication proofreading
HJW74_RS21515	COG0564	pseudouridine synthase activity
HJW74_RS21525	COG3493	citrate carrier protein
HJW74_RS21540	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HJW74_RS21545	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HJW74_RS21555	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HJW74_RS21600	COG0505	Belongs to the CarA family
HJW74_RS21670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HJW74_RS21695	COG1047	Peptidyl-prolyl cis-trans
HJW74_RS21710	COG0196	riboflavin kinase activity
HJW74_RS21730	COG0583	DNA-binding transcription factor activity
HJW74_RS21755	COG4735	regulation of single-species biofilm formation
HJW74_RS21760	COG1584	GPR1 FUN34 yaaH family protein
HJW74_RS21765	COG0477	Major facilitator Superfamily
HJW74_RS21770	COG0521	Mo-molybdopterin cofactor biosynthetic process
HJW74_RS21775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HJW74_RS21780	COG1115	amino acid carrier protein
HJW74_RS21795	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HJW74_RS21805	COG0460	homoserine dehydrogenase
HJW74_RS21805	COG0527	aspartate kinase activity
HJW74_RS21820	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HJW74_RS21830	COG0745	RESPONSE REGULATOR receiver
HJW74_RS21835	COG4452	Inner membrane protein CreD
HJW74_RS21840	COG2205	protein histidine kinase activity
HJW74_RS21845	COG0745	RESPONSE REGULATOR receiver
HJW74_RS21850	COG3045	CreA protein
HJW74_RS21855	COG2207	Transcriptional regulator
HJW74_RS21855	COG3708	Transcriptional regulator
HJW74_RS21875	COG0741	lytic transglycosylase activity
HJW74_RS21880	COG0488	(ABC) transporter
HJW74_RS21890	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HJW74_RS21895	COG0560	Phosphoserine phosphatase
HJW74_RS21900	COG3726	membrane protein affecting hemolysin expression
HJW74_RS21930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HJW74_RS21935	COG0084	hydrolase, TatD family'
HJW74_RS21940	COG4667	esterase of the alpha-beta hydrolase superfamily
HJW74_RS21950	COG2823	Periplasmic or secreted lipoprotein
HJW74_RS21960	COG1011	Hydrolase
HJW74_RS21965	COG0456	acetyltransferase
HJW74_RS21970	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HJW74_RS22005	COG3706	GGDEF domain
HJW74_RS22010	COG4114	ferric iron reductase
HJW74_RS22015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS22015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS22020	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HJW74_RS22025	COG2197	response regulator
HJW74_RS22030	COG2197	response regulator
HJW74_RS22045	COG2966	Psort location CytoplasmicMembrane, score
HJW74_RS22060	COG1484	DNA-dependent DNA replication
HJW74_RS22075	COG5464	transposase or invertase
HJW74_RS22080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HJW74_RS22085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HJW74_RS22090	COG3716	PTS system mannose fructose sorbose family IID component
HJW74_RS22095	COG3715	PTS system
HJW74_RS22110	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HJW74_RS22110	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HJW74_RS22115	COG0456	acetyltransferase
HJW74_RS22115	COG1214	PFAM Peptidase M22, glycoprotease
HJW74_RS22125	COG1737	Transcriptional regulator
HJW74_RS22130	COG0800	Aldolase
HJW74_RS22135	COG3734	2-keto-3-deoxy-galactonokinase
HJW74_RS22150	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HJW74_RS22170	COG0531	amino acid
HJW74_RS22175	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS22180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HJW74_RS22195	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HJW74_RS22195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HJW74_RS22210	COG1846	Transcriptional regulator
HJW74_RS22220	COG0179	Fumarylacetoacetate (FAA) hydrolase
HJW74_RS22230	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS22235	COG3384	dioxygenase
HJW74_RS22245	COG3971	2-oxopent-4-enoate hydratase activity
HJW74_RS22265	COG2368	4-hydroxyphenylacetate
HJW74_RS22270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HJW74_RS22285	COG1966	Carbon starvation protein
HJW74_RS22290	COG2879	small protein
HJW74_RS22295	COG0523	cobalamin synthesis protein
HJW74_RS22305	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS22310	COG5464	transposase or invertase
HJW74_RS22315	COG1917	Cupin 2, conserved barrel domain protein
HJW74_RS22315	COG2207	Transcriptional regulator
HJW74_RS22325	COG2733	membrane
HJW74_RS22340	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HJW74_RS22345	COG1924	4 iron, 4 sulfur cluster binding
HJW74_RS22360	COG1566	PFAM secretion protein HlyD family protein
HJW74_RS22370	COG5457	Domain of unknown function (DUF1127)
HJW74_RS22375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HJW74_RS22385	COG0583	DNA-binding transcription factor activity
HJW74_RS22390	COG2249	NAD(P)H dehydrogenase (quinone) activity
HJW74_RS22425	COG1012	belongs to the aldehyde dehydrogenase family
HJW74_RS22425	COG1454	alcohol dehydrogenase
HJW74_RS22440	COG1882	Formate acetyltransferase
HJW74_RS22445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HJW74_RS22455	COG4869	propanediol catabolic process
HJW74_RS22480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJW74_RS22485	COG1129	ABC transporter
HJW74_RS22485	COG0842	Transport permease protein
HJW74_RS22490	COG0842	Transport permease protein
HJW74_RS22520	COG2850	peptidyl-arginine hydroxylation
HJW74_RS22535	COG5002	protein histidine kinase activity
HJW74_RS22540	COG0745	RESPONSE REGULATOR receiver
HJW74_RS22545	COG1538	Outer membrane efflux protein
HJW74_RS22550	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJW74_RS22555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJW74_RS22560	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJW74_RS22570	COG3040	lipid binding
HJW74_RS22575	COG0789	Transcriptional regulator
HJW74_RS22580	COG3631	Ketosteroid isomerase-related protein
HJW74_RS22585	COG0300	oxidoreductase activity
HJW74_RS22600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HJW74_RS22620	COG3272	Protein of unknown function (DUF1722)
HJW74_RS22630	COG4580	involved in the transport of maltose and maltodextrins
HJW74_RS22645	COG2211	Major facilitator Superfamily
HJW74_RS22650	COG3507	Belongs to the glycosyl hydrolase 43 family
HJW74_RS22675	COG2003	Belongs to the UPF0758 family
HJW74_RS22700	COG2378	regulation of single-species biofilm formation
HJW74_RS22720	COG1201	RNA secondary structure unwinding
HJW74_RS22775	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HJW74_RS22790	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HJW74_RS22810	COG0288	reversible hydration of carbon dioxide
HJW74_RS22815	COG0659	secondary active sulfate transmembrane transporter activity
HJW74_RS22820	COG1064	alcohol dehydrogenase
HJW74_RS22825	COG1175	transmembrane transport
HJW74_RS22830	COG0395	ABC-type sugar transport system, permease component
HJW74_RS22835	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HJW74_RS22840	COG3842	ATPase activity
HJW74_RS22855	COG1082	Xylose isomerase domain protein TIM barrel
HJW74_RS22865	COG3962	Belongs to the TPP enzyme family
HJW74_RS22875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJW74_RS22880	COG1737	Transcriptional regulator
HJW74_RS22880	COG0837	glucose binding
HJW74_RS22885	COG3718	enzyme involved in inositol metabolism
HJW74_RS22900	COG0433	COG0433 Predicted ATPase
HJW74_RS22905	COG0795	lipopolysaccharide-transporting ATPase activity
HJW74_RS22910	COG0795	lipopolysaccharide-transporting ATPase activity
HJW74_RS22920	COG2927	DNA polymerase III (CHI subunit)
HJW74_RS22925	COG0525	valine-tRNA ligase activity
HJW74_RS22950	COG2188	Transcriptional regulator
HJW74_RS22955	COG1288	antiporter activity
HJW74_RS22960	COG1228	amidohydrolase
HJW74_RS22965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJW74_RS22970	COG2222	sugar isomerase
HJW74_RS22980	COG2731	YhcH YjgK YiaL family protein
HJW74_RS23015	COG1263	PTS System
HJW74_RS23015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJW74_RS23020	COG0366	Alpha amylase catalytic
HJW74_RS23025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJW74_RS23030	COG1486	melibiose metabolic process
HJW74_RS23055	COG0602	queuosine metabolic process
HJW74_RS23060	COG2026	Addiction module toxin, RelE StbE family
HJW74_RS23065	COG3077	Addiction module antitoxin, RelB DinJ family
HJW74_RS23070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJW74_RS23070	COG3711	transcriptional antiterminator
HJW74_RS23075	COG2706	6-phosphogluconolactonase activity
HJW74_RS23090	COG3964	amidohydrolase
HJW74_RS23125	COG0312	modulator of DNA gyrase
HJW74_RS23150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HJW74_RS23160	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS23165	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS23170	COG1129	ABC transporter
HJW74_RS23175	COG1879	ABC-type sugar transport system periplasmic component
HJW74_RS23195	COG2105	PFAM AIG2 family protein
HJW74_RS23200	COG2911	Protein conserved in bacteria
HJW74_RS23205	COG0729	surface antigen
HJW74_RS23215	COG1253	flavin adenine dinucleotide binding
HJW74_RS23240	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HJW74_RS23255	COG1733	regulation of RNA biosynthetic process
HJW74_RS23260	COG0702	epimerase
HJW74_RS23270	COG0697	spore germination
HJW74_RS23280	COG1113	amino acid transport
HJW74_RS23285	COG0545	Peptidyl-prolyl cis-trans isomerase
HJW74_RS23290	COG3061	Opacity-associated protein A
HJW74_RS23300	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HJW74_RS23305	COG2965	DNA replication, synthesis of RNA primer
HJW74_RS23365	COG1073	alpha beta
HJW74_RS23370	COG3650	response to hydrogen peroxide
HJW74_RS23380	COG1960	acyl-CoA dehydrogenase activity
HJW74_RS23385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HJW74_RS23390	COG0557	exoribonuclease II activity
HJW74_RS23405	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HJW74_RS23415	COG0330	HflC and HflK could
HJW74_RS23420	COG0330	HflC and HflK could
HJW74_RS23425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HJW74_RS23450	COG0860	N-Acetylmuramoyl-L-alanine amidase
HJW74_RS23455	COG0802	atpase or kinase
HJW74_RS23460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HJW74_RS23460	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HJW74_RS23465	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HJW74_RS23485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJW74_RS23505	COG1511	domain protein
HJW74_RS23505	COG3264	Mechanosensitive ion channel
HJW74_RS23520	COG1053	succinate dehydrogenase
HJW74_RS23525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HJW74_RS23545	COG2076	Multidrug Resistance protein
HJW74_RS23550	COG5510	response to toxic substance
HJW74_RS23565	COG1509	lysine 2,3-aminomutase activity
HJW74_RS23635	COG0531	amino acid
HJW74_RS23640	COG3030	protein affecting phage T7 exclusion by the F plasmid
HJW74_RS23645	COG1027	Aspartate ammonia-lyase
HJW74_RS23650	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HJW74_RS23665	COG1309	transcriptional regulator
HJW74_RS23705	COG0457	Tetratricopeptide repeat
HJW74_RS23710	COG1649	PFAM Uncharacterised BCR, COG1649
HJW74_RS23710	COG0726	polysaccharide deacetylase
HJW74_RS23715	COG1215	transferase activity, transferring glycosyl groups
HJW74_RS23735	COG0861	Integral membrane protein TerC family
HJW74_RS23775	COG1486	melibiose metabolic process
HJW74_RS23780	COG2169	Transcriptional regulator
HJW74_RS23790	COG2824	Alkylphosphonate utilization operon protein PhnA
HJW74_RS23795	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HJW74_RS23800	COG2188	Transcriptional regulator
HJW74_RS23805	COG3624	Phosphonate C-P lyase system protein PhnG
HJW74_RS23810	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HJW74_RS23815	COG3626	phosphonate metabolism
HJW74_RS23820	COG3627	carbon phosphorus lyase activity
HJW74_RS23825	COG4107	phosphonate C-P lyase system protein PhnK
HJW74_RS23830	COG4778	phosphonate C-P lyase system protein PhnL
HJW74_RS23835	COG3454	Phosphonate metabolism
HJW74_RS23845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HJW74_RS23855	COG4191	Histidine kinase
HJW74_RS23855	COG0784	Response regulator, receiver
HJW74_RS23860	COG1129	ABC transporter
HJW74_RS23865	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS23900	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HJW74_RS23905	COG1301	dicarboxylic acid transport
HJW74_RS23915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HJW74_RS23920	COG3162	membrane
HJW74_RS23950	COG3539	Fimbrial protein
HJW74_RS23960	COG1346	cytolysis
HJW74_RS23965	COG1380	Effector of murein hydrolase LrgA
HJW74_RS23970	COG0583	DNA-binding transcription factor activity
HJW74_RS23975	COG0025	NhaP-type Na H and K H
HJW74_RS23980	COG2252	PERMEase
HJW74_RS23985	COG0625	glutathione transferase activity
HJW74_RS23990	COG0789	Transcriptional regulator
HJW74_RS24000	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HJW74_RS24030	COG1234	tRNA 3'-trailer cleavage
HJW74_RS24035	COG1609	Transcriptional regulator
HJW74_RS24040	COG0483	inositol monophosphate 1-phosphatase activity
HJW74_RS24050	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HJW74_RS24075	COG4771	TonB-dependent receptor
HJW74_RS24085	COG0741	lytic transglycosylase activity
HJW74_RS24100	COG2315	Protein conserved in bacteria
HJW74_RS24105	COG0432	Pfam Uncharacterised protein family UPF0047
HJW74_RS24120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HJW74_RS24125	COG0305	Participates in initiation and elongation during chromosome replication
HJW74_RS24140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HJW74_RS24150	COG0735	belongs to the Fur family
HJW74_RS24155	COG3237	CsbD-like
HJW74_RS24165	COG0534	Mate efflux family protein
HJW74_RS24175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HJW74_RS24245	COG0251	oxidation-reduction process
HJW74_RS24255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HJW74_RS24265	COG0527	aspartate kinase activity
HJW74_RS24320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HJW74_RS24350	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HJW74_RS24360	COG0456	acetyltransferase
HJW74_RS24390	COG0151	Belongs to the GarS family
HJW74_RS24400	COG4191	Histidine kinase
HJW74_RS24405	COG3678	ATP-independent chaperone mediated protein folding
HJW74_RS24440	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HJW74_RS24455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HJW74_RS24460	COG2104	thiamine diphosphate biosynthetic process
HJW74_RS24475	COG3706	GGDEF domain
HJW74_RS24485	COG1447	Phosphotransferase system cellobiose-specific component IIA
HJW74_RS24490	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HJW74_RS24525	COG0250	Participates in transcription elongation, termination and antitermination
HJW74_RS24570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HJW74_RS24600	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HJW74_RS24610	COG1739	Uncharacterized protein family UPF0029
HJW74_RS24655	COG0805	protein transport
HJW74_RS24675	COG3165	ubiquinone biosynthetic process from chorismate
HJW74_RS24705	COG0583	DNA-binding transcription factor activity
HJW74_RS24710	COG0697	spore germination
HJW74_RS24715	COG0561	phosphatase activity
HJW74_RS24720	COG2267	carboxylic ester hydrolase activity
HJW74_RS24725	COG1280	lysine exporter protein (LysE YggA)
HJW74_RS24735	COG1280	lysine exporter protein (LysE YggA)
HJW74_RS24765	COG0210	DNA helicase
HJW74_RS24770	COG1011	Hydrolase
HJW74_RS24800	COG3072	Adenylate cyclase
HJW74_RS24815	COG2959	enzyme of heme biosynthesis
HJW74_RS24820	COG3071	HemY protein
HJW74_RS24870	COG2244	polysaccharide biosynthetic process
HJW74_RS24875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HJW74_RS24880	COG0456	acetyltransferase
HJW74_RS24885	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HJW74_RS24890	COG1088	dTDP-glucose 4,6-dehydratase activity
HJW74_RS24895	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HJW74_RS24900	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HJW74_RS24910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HJW74_RS24915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HJW74_RS24920	COG3118	belongs to the thioredoxin family
HJW74_RS24945	COG1811	Na channel or pump
HJW74_RS24955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HJW74_RS24960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HJW74_RS24970	COG0583	DNA-binding transcription factor activity
HJW74_RS24975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HJW74_RS24990	COG3978	acetolactate synthase activity
HJW74_RS25010	COG3085	chromosome segregation
HJW74_RS25085	COG0583	DNA-binding transcription factor activity
HJW74_RS25100	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HJW74_RS25115	COG3443	Belongs to the bacterial solute-binding protein 9 family
HJW74_RS25120	COG2207	Transcriptional regulator
HJW74_RS25130	COG0371	Dehydrogenase
HJW74_RS25135	COG0697	spore germination
HJW74_RS25145	COG0583	DNA-binding transcription factor activity
HJW74_RS25155	COG0737	Belongs to the 5'-nucleotidase family
HJW74_RS25165	COG0460	homoserine dehydrogenase
HJW74_RS25165	COG0527	aspartate kinase activity
HJW74_RS25170	COG0626	cystathionine gamma-synthase activity
HJW74_RS25185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HJW74_RS25190	COG1609	Transcriptional regulator
HJW74_RS25195	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HJW74_RS25210	COG1575	Belongs to the MenA family. Type 1 subfamily
HJW74_RS25230	COG3678	ATP-independent chaperone mediated protein folding
HJW74_RS25235	COG0745	RESPONSE REGULATOR receiver
HJW74_RS25240	COG2205	protein histidine kinase activity
HJW74_RS25245	COG2258	MOSC domain
HJW74_RS25250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HJW74_RS25290	COG1129	ABC transporter
HJW74_RS25295	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS25300	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS25305	COG1454	alcohol dehydrogenase
HJW74_RS25315	COG2211	Major facilitator Superfamily
HJW74_RS25375	COG0205	6-phosphofructokinase activity
HJW74_RS25395	COG0437	4 iron, 4 sulfur cluster binding
HJW74_RS25400	COG2864	formate dehydrogenase
HJW74_RS25415	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HJW74_RS25425	COG0456	acetyltransferase
HJW74_RS25440	COG1011	Hydrolase
HJW74_RS25455	COG3852	Histidine kinase
HJW74_RS25470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HJW74_RS25490	COG0204	Acyl-transferase
HJW74_RS25500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HJW74_RS25505	COG3084	Protein conserved in bacteria
HJW74_RS25515	COG1763	Mo-molybdopterin cofactor biosynthetic process
HJW74_RS25540	COG2186	Transcriptional regulator
HJW74_RS25545	COG0477	Major facilitator Superfamily
HJW74_RS25550	COG1609	Transcriptional regulator
HJW74_RS25555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJW74_RS25565	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJW74_RS25570	COG1129	ABC transporter
HJW74_RS25600	COG1522	sequence-specific DNA binding
HJW74_RS25605	COG0716	FMN binding
HJW74_RS25620	COG3312	ion transport
HJW74_RS25685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HJW74_RS25690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HJW74_RS25695	COG0573	inorganic phosphate transmembrane transporter activity
HJW74_RS25700	COG0581	inorganic phosphate transmembrane transporter activity
HJW74_RS25705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HJW74_RS25710	COG0704	Plays a role in the regulation of phosphate uptake
HJW74_RS25725	COG2382	esterase
HJW74_RS25730	COG0363	glucosamine-6-phosphate deaminase activity
HJW74_RS25735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HJW74_RS25745	COG2252	PERMEase
HJW74_RS25750	COG0431	NADPH-dependent FMN reductase
HJW74_RS25755	COG2091	lysine biosynthetic process via aminoadipic acid
HJW74_RS25785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HJW74_RS25810	COG2203	Gaf domain
HJW74_RS25810	COG2199	diguanylate cyclase activity
HJW74_RS25815	COG1716	ATPase activity
HJW74_RS25815	COG5001	Diguanylate cyclase
HJW74_RS25830	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HJW74_RS25840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HJW74_RS25885	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJW74_RS25915	COG0739	heme binding
HJW74_RS25925	COG2132	Multicopper oxidase
HJW74_RS25930	COG3667	copper resistance
HJW74_RS25935	COG2372	response to copper ion
HJW74_RS25940	COG1276	copper resistance
HJW74_RS25945	COG0745	RESPONSE REGULATOR receiver
HJW74_RS25950	COG2205	protein histidine kinase activity
HJW74_RS25970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HJW74_RS25985	COG0431	NADPH-dependent FMN reductase
HJW74_RS26015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HJW74_RS26080	COG2801	Transposase and inactivated derivatives
HJW74_RS26095	COG0501	Belongs to the peptidase M48B family
HJW74_RS26110	COG0542	response to heat
HJW74_RS26115	COG0071	Belongs to the small heat shock protein (HSP20) family
HJW74_RS26145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HJW74_RS26170	COG0683	leucine binding
HJW74_RS26175	COG2198	Histidine kinase
HJW74_RS26175	COG0784	Response regulator, receiver
HJW74_RS26175	COG5002	protein histidine kinase activity
HJW74_RS26180	COG0745	RESPONSE REGULATOR receiver
HJW74_RS26310	COG1660	Displays ATPase and GTPase activities
HJW74_RS26365	COG0697	spore germination
HJW74_RS26385	COG4644	lycopene metabolic process
HJW74_RS26465	COG3344	reverse transcriptase