locus-tag	class	description
AM425_RS00010	COG1473	amidohydrolase
AM425_RS00015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM425_RS00020	COG0667	Aldo Keto reductase
AM425_RS00065	COG4680	protein conserved in bacteria
AM425_RS00080	COG0531	amino acid
AM425_RS00090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM425_RS00095	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS00110	COG1113	amino acid transport
AM425_RS00115	COG2211	Major facilitator Superfamily
AM425_RS00125	COG0673	inositol 2-dehydrogenase activity
AM425_RS00135	COG1609	Transcriptional regulator
AM425_RS00140	COG0668	transmembrane transport
AM425_RS00145	COG0477	Major facilitator Superfamily
AM425_RS00165	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AM425_RS00165	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM425_RS00170	COG2222	sugar isomerase
AM425_RS00175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM425_RS00180	COG3716	PTS system mannose fructose sorbose family IID component
AM425_RS00190	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM425_RS00200	COG0778	Nitroreductase
AM425_RS00205	COG2315	Protein conserved in bacteria
AM425_RS00250	COG3698	Phosphodiester glycosidase
AM425_RS00260	COG4166	transmembrane transport
AM425_RS00270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM425_RS00275	COG4608	Belongs to the ABC transporter superfamily
AM425_RS00290	COG0697	spore germination
AM425_RS00305	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM425_RS00310	COG0765	amino acid transport
AM425_RS00315	COG4215	(ABC) transporter
AM425_RS00325	COG4221	oxidoreductase activity
AM425_RS00330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM425_RS00335	COG4608	Belongs to the ABC transporter superfamily
AM425_RS00340	COG0444	Belongs to the ABC transporter superfamily
AM425_RS00345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM425_RS00350	COG0601	transmembrane transport
AM425_RS00355	COG0747	negative chemotaxis
AM425_RS00385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM425_RS00395	COG0668	transmembrane transport
AM425_RS00400	COG0583	DNA-binding transcription factor activity
AM425_RS00410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM425_RS00420	COG3958	Transketolase
AM425_RS00425	COG3959	Transketolase, thiamine diphosphate binding domain
AM425_RS00430	COG2390	Transcriptional regulator
AM425_RS00435	COG5464	transposase or invertase
AM425_RS00440	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM425_RS00445	COG1129	ABC transporter
AM425_RS00455	COG1879	ABC-type sugar transport system periplasmic component
AM425_RS00465	COG4771	TonB-dependent receptor
AM425_RS00470	COG2382	esterase
AM425_RS00475	COG3251	PFAM MbtH domain protein
AM425_RS00480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM425_RS00480	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM425_RS00485	COG1120	ATPase activity
AM425_RS00490	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM425_RS00495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM425_RS00505	COG4592	Periplasmic binding protein
AM425_RS00510	COG1169	isochorismate synthase
AM425_RS00515	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM425_RS00520	COG3433	isochorismatase activity
AM425_RS00520	COG1535	isochorismatase
AM425_RS00525	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS00535	COG1966	Carbon starvation protein
AM425_RS00540	COG2879	small protein
AM425_RS00555	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS00560	COG0371	Dehydrogenase
AM425_RS00565	COG1129	ABC transporter
AM425_RS00570	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM425_RS00600	COG2271	Major facilitator Superfamily
AM425_RS00605	COG0483	inositol monophosphate 1-phosphatase activity
AM425_RS00615	COG0402	S-adenosylhomocysteine deaminase activity
AM425_RS00625	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM425_RS00640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM425_RS00650	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM425_RS00655	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM425_RS00660	COG1129	ABC transporter
AM425_RS00685	COG0436	Aminotransferase
AM425_RS00690	COG1475	DNA binding
AM425_RS00695	COG3969	phosphoadenosine phosphosulfate
AM425_RS00700	COG0583	DNA-binding transcription factor activity
AM425_RS00705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM425_RS00725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM425_RS00730	COG3719	Belongs to the RNase T2 family
AM425_RS00735	COG3069	C4-dicarboxylate transmembrane transporter activity
AM425_RS00755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM425_RS00770	COG0583	DNA-binding transcription factor activity
AM425_RS00785	COG1686	Belongs to the peptidase S11 family
AM425_RS00790	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM425_RS00795	COG0772	Belongs to the SEDS family
AM425_RS00800	COG0768	penicillin binding
AM425_RS00810	COG0799	negative regulation of ribosome biogenesis
AM425_RS00830	COG1466	dna polymerase III delta subunit
AM425_RS00845	COG2888	peptidyl-tyrosine sulfation
AM425_RS00860	COG1126	abc transporter atp-binding protein
AM425_RS00865	COG0765	amino acid transport
AM425_RS00870	COG0765	amino acid transport
AM425_RS00895	COG1702	phosphate starvation-inducible protein PhoH
AM425_RS00905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM425_RS00950	COG0367	asparagine synthase
AM425_RS00955	COG0647	UMP catabolic process
AM425_RS00960	COG1940	carbohydrate kinase activity
AM425_RS00960	COG1846	Transcriptional regulator
AM425_RS00965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM425_RS01010	COG0735	belongs to the Fur family
AM425_RS01025	COG0596	Alpha beta hydrolase
AM425_RS01035	COG0033	Phosphoglucomutase
AM425_RS01045	COG0745	RESPONSE REGULATOR receiver
AM425_RS01050	COG2205	protein histidine kinase activity
AM425_RS01080	COG0415	Belongs to the DNA photolyase family
AM425_RS01095	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM425_RS01100	COG1984	allophanate hydrolase subunit 2
AM425_RS01145	COG2009	succinate dehydrogenase
AM425_RS01150	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM425_RS01155	COG1053	succinate dehydrogenase
AM425_RS01160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM425_RS01165	COG0567	Dehydrogenase, E1 component
AM425_RS01170	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM425_RS01185	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM425_RS01195	COG1271	oxidase subunit
AM425_RS01200	COG1294	oxidase, subunit
AM425_RS01205	COG4890	Cyd operon protein YbgT
AM425_RS01210	COG3790	cyd operon protein YbgE
AM425_RS01215	COG0824	Thioesterase
AM425_RS01220	COG0811	peptide transport
AM425_RS01225	COG0848	biopolymer transport protein
AM425_RS01230	COG3064	Membrane
AM425_RS01240	COG2885	chlorophyll binding
AM425_RS01245	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM425_RS01290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM425_RS01295	COG3201	nicotinamide mononucleotide transporter
AM425_RS01310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM425_RS01320	COG2017	converts alpha-aldose to the beta-anomer
AM425_RS01330	COG1085	galactose-1-phosphate uridylyltransferase
AM425_RS01340	COG1119	ATPase activity
AM425_RS01345	COG2005	Transcriptional regulator
AM425_RS01345	COG3585	molybdate ion transport
AM425_RS01355	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM425_RS01360	COG4149	molybdate abc transporter
AM425_RS01370	COG0561	phosphatase activity
AM425_RS01395	COG2200	EAL domain
AM425_RS01400	COG0789	Transcriptional regulator
AM425_RS01430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM425_RS01435	COG0589	response to stress
AM425_RS01445	COG4677	pectinesterase activity
AM425_RS01485	COG1881	PFAM PEBP family protein
AM425_RS01490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM425_RS01505	COG2226	methyltransferase
AM425_RS01545	COG0642	Histidine kinase
AM425_RS01550	COG0745	RESPONSE REGULATOR receiver
AM425_RS01575	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM425_RS01585	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM425_RS01590	COG0314	molybdopterin synthase activity
AM425_RS01595	COG0670	Belongs to the BI1 family
AM425_RS01600	COG0392	lysyltransferase activity
AM425_RS01605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM425_RS01610	COG3568	Endonuclease Exonuclease Phosphatase
AM425_RS01625	COG0842	Transport permease protein
AM425_RS01630	COG0842	Transport permease protein
AM425_RS01635	COG1131	(ABC) transporter
AM425_RS01640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM425_RS01645	COG1309	transcriptional regulator
AM425_RS01650	COG0583	DNA-binding transcription factor activity
AM425_RS01655	COG2271	Major facilitator Superfamily
AM425_RS01660	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS01665	COG3959	Transketolase, thiamine diphosphate binding domain
AM425_RS01670	COG3958	Transketolase
AM425_RS01675	COG0513	Belongs to the DEAD box helicase family
AM425_RS01680	COG1199	ATP-dependent helicase activity
AM425_RS01685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM425_RS01695	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM425_RS01705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM425_RS01715	COG0668	transmembrane transport
AM425_RS01720	COG1126	abc transporter atp-binding protein
AM425_RS01725	COG0765	amino acid transport
AM425_RS01730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM425_RS01745	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM425_RS01750	COG2194	sulfuric ester hydrolase activity
AM425_RS01765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM425_RS01770	COG2723	6-phospho-beta-galactosidase activity
AM425_RS01775	COG2188	Transcriptional regulator
AM425_RS01780	COG1376	ErfK ybiS ycfS ynhG family protein
AM425_RS01785	COG2365	Tyrosine phosphatase family
AM425_RS01790	COG0488	(ABC) transporter
AM425_RS01800	COG2271	Major facilitator Superfamily
AM425_RS01805	COG1609	Transcriptional regulator
AM425_RS01815	COG0561	phosphatase activity
AM425_RS01820	COG1882	Formate acetyltransferase
AM425_RS01825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM425_RS01830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM425_RS01835	COG0303	'Molybdopterin
AM425_RS01850	COG0747	negative chemotaxis
AM425_RS01875	COG2223	nitrite transmembrane transporter activity
AM425_RS01885	COG2133	pyrroloquinoline quinone binding
AM425_RS01890	COG0625	glutathione transferase activity
AM425_RS01895	COG1686	Belongs to the peptidase S11 family
AM425_RS01900	COG1349	DNA-binding transcription factor activity
AM425_RS01905	COG0671	phosphoesterase, PA-phosphatase related
AM425_RS01915	COG2814	Major facilitator Superfamily
AM425_RS01920	COG0561	phosphatase activity
AM425_RS01925	COG0738	Major facilitator superfamily
AM425_RS01930	COG3226	Transcriptional regulator
AM425_RS01955	COG0778	Nitroreductase
AM425_RS01970	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM425_RS01975	COG3842	ATPase activity
AM425_RS01980	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM425_RS01985	COG1177	transmembrane transport
AM425_RS02000	COG0745	RESPONSE REGULATOR receiver
AM425_RS02005	COG5002	protein histidine kinase activity
AM425_RS02010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM425_RS02015	COG4160	amino acid transport
AM425_RS02020	COG4215	(ABC) transporter
AM425_RS02025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM425_RS02030	COG1126	abc transporter atp-binding protein
AM425_RS02045	COG3706	GGDEF domain
AM425_RS02045	COG4251	negative regulation of phosphorylation
AM425_RS02045	COG5001	Diguanylate cyclase
AM425_RS02045	COG2203	Gaf domain
AM425_RS02050	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM425_RS02055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM425_RS02060	COG0702	epimerase
AM425_RS02065	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM425_RS02070	COG0028	Belongs to the TPP enzyme family
AM425_RS02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM425_RS02090	COG2431	L-lysine efflux transmembrane transporter activity
AM425_RS02100	COG3593	DNA synthesis involved in DNA repair
AM425_RS02105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM425_RS02120	COG1278	Cold shock
AM425_RS02130	COG0542	response to heat
AM425_RS02145	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM425_RS02150	COG4988	ABC transporter
AM425_RS02155	COG0492	ferredoxin-NADP+ reductase activity
AM425_RS02165	COG1178	ABC-type Fe3 transport system permease component
AM425_RS02165	COG1674	ftsk spoiiie
AM425_RS02175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM425_RS02185	COG0243	molybdopterin cofactor binding
AM425_RS02190	COG0437	4 iron, 4 sulfur cluster binding
AM425_RS02195	COG3302	dmso reductase anchor subunit
AM425_RS02205	COG0477	Major facilitator Superfamily
AM425_RS02210	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM425_RS02215	COG1882	Formate acetyltransferase
AM425_RS02220	COG2116	formate transmembrane transporter activity
AM425_RS02225	COG1944	ATP diphosphatase activity
AM425_RS02230	COG2323	membrane
AM425_RS02250	COG0539	negative regulation of cytoplasmic translation
AM425_RS02260	COG2333	competence protein COMEC
AM425_RS02260	COG0658	competence protein
AM425_RS02275	COG3214	Protein conserved in bacteria
AM425_RS02290	COG3173	Aminoglycoside phosphotransferase
AM425_RS02295	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM425_RS02300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM425_RS02310	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AM425_RS02320	COG2989	Protein conserved in bacteria
AM425_RS02330	COG3108	Peptidase M15
AM425_RS02335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM425_RS02340	COG1448	Aminotransferase
AM425_RS02355	COG1522	sequence-specific DNA binding
AM425_RS02365	COG0814	amino acid
AM425_RS02375	COG1473	amidohydrolase
AM425_RS02390	COG0308	aminopeptidase N
AM425_RS02400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM425_RS02405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM425_RS02410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM425_RS02415	COG0431	NADPH-dependent FMN reductase
AM425_RS02430	COG0633	Ferredoxin
AM425_RS02430	COG3217	Mosc domain protein beta barrel domain protein
AM425_RS02440	COG0488	(ABC) transporter
AM425_RS02445	COG2995	paraquat-inducible protein a
AM425_RS02450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM425_RS02450	COG3008	intermembrane lipid transfer
AM425_RS02455	COG3009	Protein conserved in bacteria
AM425_RS02465	COG3130	regulation of translation
AM425_RS02475	COG1067	ATP-dependent peptidase activity
AM425_RS02500	COG3070	regulator of competence-specific genes
AM425_RS02505	COG1289	transmembrane transporter activity
AM425_RS02510	COG3304	Inner membrane component domain
AM425_RS02515	COG0210	DNA helicase
AM425_RS02525	COG1832	CoA-binding protein
AM425_RS02540	COG1881	PFAM PEBP family protein
AM425_RS02545	COG2207	Transcriptional regulator
AM425_RS02560	COG0670	Belongs to the BI1 family
AM425_RS02590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM425_RS02595	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS02600	COG4638	Rieske (2fe-2S)
AM425_RS02605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM425_RS02615	COG0473	3-isopropylmalate dehydrogenase activity
AM425_RS02620	COG0583	DNA-binding transcription factor activity
AM425_RS02625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM425_RS02630	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS02635	COG1396	sequence-specific DNA binding
AM425_RS02635	COG1917	Cupin 2, conserved barrel domain protein
AM425_RS02640	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM425_RS02645	COG0174	glutamine synthetase
AM425_RS02655	COG0531	amino acid
AM425_RS02670	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS02695	COG3729	General stress protein
AM425_RS02705	COG2233	PERMEase
AM425_RS02740	COG1309	transcriptional regulator
AM425_RS02760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM425_RS02770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM425_RS02790	COG1702	phosphate starvation-inducible protein PhoH
AM425_RS02795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM425_RS02805	COG1335	isochorismatase
AM425_RS02815	COG0583	DNA-binding transcription factor activity
AM425_RS02820	COG1309	transcriptional regulator
AM425_RS02850	COG3381	protein complex oligomerization
AM425_RS02890	COG5645	(Lipo)protein
AM425_RS02910	COG1560	Kdo2-lipid A biosynthetic process
AM425_RS02960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM425_RS02980	COG2814	Major facilitator Superfamily
AM425_RS02985	COG0583	DNA-binding transcription factor activity
AM425_RS02990	COG1530	ribonuclease E activity
AM425_RS03010	COG1399	metal-binding, possibly nucleic acid-binding protein
AM425_RS03030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM425_RS03045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM425_RS03050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM425_RS03055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM425_RS03065	COG0470	DNA polymerase III
AM425_RS03070	COG0084	hydrolase, TatD family'
AM425_RS03080	COG0537	adenosine 5'-monophosphoramidase activity
AM425_RS03085	COG5633	Lipoprotein
AM425_RS03110	COG1252	NADH dehydrogenase
AM425_RS03115	COG3134	Outer membrane lipoprotein
AM425_RS03125	COG1309	transcriptional regulator
AM425_RS03135	COG1376	ErfK ybiS ycfS ynhG family protein
AM425_RS03135	COG1388	LysM domain
AM425_RS03140	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM425_RS03145	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM425_RS03155	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM425_RS03165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM425_RS03175	COG2390	Transcriptional regulator
AM425_RS03190	COG3395	kinase activity
AM425_RS03205	COG0698	ribose 5-phosphate isomerase
AM425_RS03210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM425_RS03215	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM425_RS03220	COG0318	PFAM AMP-dependent synthetase and ligase
AM425_RS03235	COG1177	transmembrane transport
AM425_RS03255	COG2850	peptidyl-arginine hydroxylation
AM425_RS03260	COG2205	protein histidine kinase activity
AM425_RS03280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM425_RS03300	COG1187	pseudouridine synthase activity
AM425_RS03305	COG0538	isocitrate dehydrogenase activity
AM425_RS03310	COG0640	Transcriptional regulator
AM425_RS03330	COG3813	Protein conserved in bacteria
AM425_RS03335	COG1063	alcohol dehydrogenase
AM425_RS03340	COG3729	General stress protein
AM425_RS03345	COG3685	Protein conserved in bacteria
AM425_RS03350	COG3685	Protein conserved in bacteria
AM425_RS03360	COG1271	oxidase subunit
AM425_RS03365	COG1294	oxidase, subunit
AM425_RS03390	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM425_RS03395	COG0583	DNA-binding transcription factor activity
AM425_RS03400	COG3706	GGDEF domain
AM425_RS03405	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AM425_RS03420	COG1560	Kdo2-lipid A biosynthetic process
AM425_RS03430	COG3182	Iron-regulated membrane protein
AM425_RS03450	COG2199	diguanylate cyclase activity
AM425_RS03450	COG2203	Gaf domain
AM425_RS03455	COG3042	response to heat
AM425_RS03460	COG3189	MarR family transcriptional regulator
AM425_RS03465	COG1683	Conserved Protein
AM425_RS03470	COG0504	CTP synthase activity
AM425_RS03475	COG2807	transmembrane transport
AM425_RS03480	COG2207	Transcriptional regulator
AM425_RS03490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM425_RS03495	COG0859	PFAM glycosyl transferase family 9
AM425_RS03510	COG3344	reverse transcriptase
AM425_RS03515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM425_RS03520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM425_RS03525	COG0583	DNA-binding transcription factor activity
AM425_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS03550	COG0386	Belongs to the glutathione peroxidase family
AM425_RS03565	COG2766	serine protein kinase
AM425_RS03570	COG3713	MltA-interacting MipA family protein
AM425_RS03575	COG0656	L-ascorbic acid biosynthetic process
AM425_RS03595	COG3139	Protein of unknown function (DUF1315)
AM425_RS03610	COG1335	isochorismatase
AM425_RS03615	COG0252	asparaginase activity
AM425_RS03620	COG0616	signal peptide processing
AM425_RS03625	COG0778	Nitroreductase
AM425_RS03640	COG0709	Synthesizes selenophosphate from selenide and ATP
AM425_RS03645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM425_RS03650	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS03650	COG0604	alcohol dehydrogenase
AM425_RS03650	COG3321	synthase
AM425_RS03655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM425_RS03660	COG0494	nUDIX hydrolase
AM425_RS03665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM425_RS03670	COG2897	thiosulfate sulfurtransferase activity
AM425_RS03675	COG4136	ATPase activity
AM425_RS03680	COG4135	transport system, permease component
AM425_RS03685	COG4134	Bacterial extracellular solute-binding protein
AM425_RS03690	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM425_RS03695	COG0398	Pfam SNARE associated Golgi protein
AM425_RS03700	COG0398	Pfam SNARE associated Golgi protein
AM425_RS03705	COG0708	Exodeoxyribonuclease III
AM425_RS03715	COG3138	arginine N-succinyltransferase
AM425_RS03725	COG3724	N-succinylarginine dihydrolase activity
AM425_RS03735	COG3678	ATP-independent chaperone mediated protein folding
AM425_RS03740	COG0322	excinuclease ABC activity
AM425_RS03750	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM425_RS03755	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM425_RS03760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM425_RS03765	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM425_RS03770	COG2169	Transcriptional regulator
AM425_RS03770	COG1917	Cupin 2, conserved barrel domain protein
AM425_RS03775	COG1486	melibiose metabolic process
AM425_RS03785	COG0753	catalase activity
AM425_RS03795	COG1823	symporter activity
AM425_RS03800	COG1988	membrane-bound metal-dependent
AM425_RS03805	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS03810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM425_RS03840	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM425_RS03845	COG3047	cAMP biosynthetic process
AM425_RS03855	COG4774	siderophore transport
AM425_RS03890	COG0135	phosphoribosylanthranilate isomerase activity
AM425_RS03890	COG0134	indole-3-glycerol-phosphate synthase activity
AM425_RS03895	COG0512	Glutamine amidotransferase of anthranilate synthase
AM425_RS03895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM425_RS03900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM425_RS03910	COG0009	L-threonylcarbamoyladenylate synthase
AM425_RS03920	COG0583	DNA-binding transcription factor activity
AM425_RS03930	COG0653	protein targeting
AM425_RS03950	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM425_RS03955	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS03965	COG0616	signal peptide processing
AM425_RS04000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM425_RS04010	COG0671	phosphoesterase, PA-phosphatase related
AM425_RS04015	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM425_RS04020	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM425_RS04030	COG0023	Translation Initiation Factor
AM425_RS04040	COG1349	DNA-binding transcription factor activity
AM425_RS04055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM425_RS04055	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM425_RS04060	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM425_RS04070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM425_RS04085	COG4171	peptide transport system, permease
AM425_RS04100	COG0702	epimerase
AM425_RS04115	COG1473	amidohydrolase
AM425_RS04125	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM425_RS04130	COG1842	Phage shock protein A
AM425_RS04140	COG1983	PspC domain protein
AM425_RS04150	COG3106	COG3106 Predicted ATPase
AM425_RS04160	COG0583	DNA-binding transcription factor activity
AM425_RS04165	COG1486	melibiose metabolic process
AM425_RS04175	COG3180	Ammonia monooxygenase
AM425_RS04180	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM425_RS04185	COG4948	Mandelate Racemase Muconate Lactonizing
AM425_RS04190	COG2866	Carboxypeptidase
AM425_RS04195	COG4166	transmembrane transport
AM425_RS04225	COG0656	L-ascorbic acid biosynthetic process
AM425_RS04245	COG0583	DNA-binding transcription factor activity
AM425_RS04250	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS04255	COG1078	dGTPase activity
AM425_RS04260	COG0693	protein deglycase activity
AM425_RS04285	COG2885	chlorophyll binding
AM425_RS04370	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS04375	COG1309	transcriptional regulator
AM425_RS04380	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS04400	COG0583	DNA-binding transcription factor activity
AM425_RS04425	COG0604	alcohol dehydrogenase
AM425_RS04430	COG0436	Aminotransferase
AM425_RS04445	COG2011	ABC-type metal ion transport system permease component
AM425_RS04450	COG1448	Aminotransferase
AM425_RS04460	COG1522	sequence-specific DNA binding
AM425_RS04465	COG1113	amino acid transport
AM425_RS04480	COG0673	inositol 2-dehydrogenase activity
AM425_RS04485	COG1349	DNA-binding transcription factor activity
AM425_RS04505	COG0513	Belongs to the DEAD box helicase family
AM425_RS04515	COG0589	response to stress
AM425_RS04525	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM425_RS04530	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM425_RS04530	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM425_RS04530	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM425_RS04530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM425_RS04540	COG3042	response to heat
AM425_RS04545	COG3187	Heat shock protein
AM425_RS04550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM425_RS04555	COG0586	Pfam SNARE associated Golgi protein
AM425_RS04560	COG2911	Protein conserved in bacteria
AM425_RS04570	COG3784	Protein of unknown function (DUF1318)
AM425_RS04575	COG2207	Transcriptional regulator
AM425_RS04580	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS04595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM425_RS04605	COG1126	abc transporter atp-binding protein
AM425_RS04615	COG0583	DNA-binding transcription factor activity
AM425_RS04620	COG2072	flavoprotein involved in K transport
AM425_RS04635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM425_RS04660	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS04660	COG2030	dehydratase
AM425_RS04665	COG3396	Phenylacetate-CoA oxygenase
AM425_RS04670	COG3460	Phenylacetate-CoA oxygenase
AM425_RS04675	COG3396	Phenylacetate-CoA oxygenase
AM425_RS04680	COG2151	metal-sulfur cluster biosynthetic enzyme
AM425_RS04685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM425_RS04690	COG1024	Enoyl-CoA hydratase
AM425_RS04695	COG1024	Enoyl-CoA hydratase
AM425_RS04700	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM425_RS04705	COG2050	protein possibly involved in aromatic compounds catabolism
AM425_RS04710	COG0183	Belongs to the thiolase family
AM425_RS04715	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM425_RS04720	COG3327	negative regulation of DNA-templated transcription, initiation
AM425_RS04725	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM425_RS04740	COG1643	Atp-dependent helicase
AM425_RS04745	COG4122	O-methyltransferase activity
AM425_RS04770	COG0583	DNA-binding transcription factor activity
AM425_RS04775	COG0667	Aldo Keto reductase
AM425_RS04780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM425_RS04785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM425_RS04790	COG3138	arginine N-succinyltransferase
AM425_RS04795	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS04800	COG3724	N-succinylarginine dihydrolase activity
AM425_RS04805	COG2988	succinylglutamate desuccinylase activity
AM425_RS04810	COG1113	amino acid transport
AM425_RS04815	COG0477	Major facilitator Superfamily
AM425_RS04820	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM425_RS04825	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS04830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM425_RS04835	COG0401	homolog of Blt101
AM425_RS04840	COG5562	phage envelope protein
AM425_RS04845	COG0425	Belongs to the sulfur carrier protein TusA family
AM425_RS04850	COG2391	methyltransferase activity
AM425_RS04875	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM425_RS04880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM425_RS04880	COG1263	PTS System
AM425_RS04885	COG1609	Transcriptional regulator
AM425_RS04890	COG5339	Protein conserved in bacteria
AM425_RS04895	COG1482	cell wall glycoprotein biosynthetic process
AM425_RS04900	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM425_RS04900	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM425_RS04905	COG0114	fumarate hydratase activity
AM425_RS04915	COG2205	protein histidine kinase activity
AM425_RS04925	COG0745	RESPONSE REGULATOR receiver
AM425_RS04930	COG3136	membrane protein required for alginate biosynthesis
AM425_RS04940	COG0531	amino acid
AM425_RS04960	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM425_RS04965	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM425_RS04980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM425_RS04995	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM425_RS05000	COG1473	amidohydrolase
AM425_RS05010	COG0583	DNA-binding transcription factor activity
AM425_RS05015	COG2840	Smr protein MutS2
AM425_RS05020	COG1414	Transcriptional regulator
AM425_RS05030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM425_RS05035	COG0183	Belongs to the thiolase family
AM425_RS05045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM425_RS05050	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM425_RS05070	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM425_RS05070	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM425_RS05100	COG3290	protein histidine kinase activity
AM425_RS05145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM425_RS05155	COG0679	Auxin Efflux Carrier
AM425_RS05185	COG0628	permease
AM425_RS05205	COG3591	Belongs to the peptidase S1B family
AM425_RS05215	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AM425_RS05220	COG2814	Major facilitator Superfamily
AM425_RS05225	COG0583	DNA-binding transcription factor activity
AM425_RS05230	COG1940	carbohydrate kinase activity
AM425_RS05235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM425_RS05250	COG3302	dmso reductase anchor subunit
AM425_RS05255	COG0437	4 iron, 4 sulfur cluster binding
AM425_RS05260	COG0243	molybdopterin cofactor binding
AM425_RS05275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM425_RS05290	COG2271	Major facilitator Superfamily
AM425_RS05295	COG0246	Mannitol dehydrogenase
AM425_RS05300	COG0589	response to stress
AM425_RS05305	COG1802	Transcriptional regulator
AM425_RS05310	COG4221	oxidoreductase activity
AM425_RS05325	COG2207	Transcriptional regulator
AM425_RS05330	COG2135	peptidase activity
AM425_RS05345	COG2197	response regulator
AM425_RS05360	COG0071	Belongs to the small heat shock protein (HSP20) family
AM425_RS05365	COG1546	Belongs to the CinA family
AM425_RS05370	COG2200	EAL domain
AM425_RS05385	COG3708	Transcriptional regulator
AM425_RS05385	COG2207	Transcriptional regulator
AM425_RS05390	COG2610	gluconate transmembrane transporter activity
AM425_RS05395	COG3622	Belongs to the hyi family
AM425_RS05400	COG0235	Class ii aldolase
AM425_RS05405	COG3395	kinase activity
AM425_RS05410	COG2084	Dehydrogenase
AM425_RS05415	COG1349	DNA-binding transcription factor activity
AM425_RS05430	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM425_RS05435	COG2223	nitrite transmembrane transporter activity
AM425_RS05475	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM425_RS05510	COG2814	Major facilitator Superfamily
AM425_RS05525	COG4977	sequence-specific DNA binding
AM425_RS05550	COG2271	Major facilitator Superfamily
AM425_RS05555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM425_RS05560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM425_RS05570	COG3395	kinase activity
AM425_RS05575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM425_RS05580	COG1349	DNA-binding transcription factor activity
AM425_RS05585	COG0039	L-malate dehydrogenase activity
AM425_RS05595	COG0583	DNA-binding transcription factor activity
AM425_RS05600	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS05615	COG2199	diguanylate cyclase activity
AM425_RS05690	COG0477	Major facilitator Superfamily
AM425_RS05700	COG2070	2-Nitropropane dioxygenase
AM425_RS05705	COG2011	ABC-type metal ion transport system permease component
AM425_RS05725	COG4628	conserved protein (DUF2132)
AM425_RS05740	COG2207	Transcriptional regulator
AM425_RS05770	COG2233	PERMEase
AM425_RS05775	COG3648	Uricase
AM425_RS05775	COG3195	allantoin biosynthetic process
AM425_RS05780	COG2351	hydroxyisourate hydrolase activity
AM425_RS05785	COG1396	sequence-specific DNA binding
AM425_RS05790	COG3550	peptidyl-serine autophosphorylation
AM425_RS05795	COG1649	PFAM Uncharacterised BCR, COG1649
AM425_RS05810	COG3188	usher protein
AM425_RS05845	COG5001	Diguanylate cyclase
AM425_RS05845	COG3300	MHYT domain
AM425_RS05850	COG2819	hydrolase of the alpha beta superfamily
AM425_RS05860	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS05860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS05865	COG2814	Major facilitator Superfamily
AM425_RS05880	COG1263	PTS System
AM425_RS05880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM425_RS05885	COG2186	Transcriptional regulator
AM425_RS05905	COG3835	regulator
AM425_RS05910	COG1929	Belongs to the glycerate kinase type-1 family
AM425_RS05955	COG0738	Major facilitator superfamily
AM425_RS05960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM425_RS05965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM425_RS05970	COG1349	DNA-binding transcription factor activity
AM425_RS05985	COG1349	DNA-binding transcription factor activity
AM425_RS05990	COG4977	sequence-specific DNA binding
AM425_RS06010	COG4977	sequence-specific DNA binding
AM425_RS06020	COG2801	Transposase and inactivated derivatives
AM425_RS06035	COG0667	Aldo Keto reductase
AM425_RS06040	COG3386	PFAM SMP-30 Gluconolaconase
AM425_RS06045	COG0667	Aldo Keto reductase
AM425_RS06050	COG0667	Aldo Keto reductase
AM425_RS06060	COG0456	acetyltransferase
AM425_RS06060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM425_RS06090	COG1652	LysM domain
AM425_RS06100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM425_RS06100	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM425_RS06100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM425_RS06105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM425_RS06115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM425_RS06120	COG3037	sugar-specific permease SgaT UlaA
AM425_RS06130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS06135	COG1609	Transcriptional regulator
AM425_RS06145	COG2223	nitrite transmembrane transporter activity
AM425_RS06190	COG0477	Major facilitator Superfamily
AM425_RS06195	COG4529	Protein conserved in bacteria
AM425_RS06200	COG1902	pentaerythritol trinitrate reductase activity
AM425_RS06210	COG0583	DNA-binding transcription factor activity
AM425_RS06215	COG2070	2-Nitropropane dioxygenase
AM425_RS06225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM425_RS06235	COG0765	amino acid transport
AM425_RS06280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM425_RS06300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM425_RS06320	COG2207	Transcriptional regulator
AM425_RS06340	COG1335	isochorismatase
AM425_RS06350	COG0406	alpha-ribazole phosphatase activity
AM425_RS06385	COG1953	Uracil, thiamine, allantoin
AM425_RS06390	COG0402	S-adenosylhomocysteine deaminase activity
AM425_RS06395	COG3706	GGDEF domain
AM425_RS06410	COG0673	inositol 2-dehydrogenase activity
AM425_RS06425	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM425_RS06430	COG1116	anion transmembrane transporter activity
AM425_RS06435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM425_RS06440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM425_RS06445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM425_RS06450	COG0076	glutamate decarboxylase activity
AM425_RS06465	COG2205	protein histidine kinase activity
AM425_RS06475	COG0596	Alpha beta hydrolase
AM425_RS06515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM425_RS06515	COG0519	Catalyzes the synthesis of GMP from XMP
AM425_RS06535	COG0583	DNA-binding transcription factor activity
AM425_RS06545	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM425_RS06550	COG1285	pathogenesis
AM425_RS06560	COG2814	Major facilitator Superfamily
AM425_RS06565	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM425_RS06570	COG0583	DNA-binding transcription factor activity
AM425_RS06575	COG0243	molybdopterin cofactor binding
AM425_RS06580	COG3781	membrane
AM425_RS06605	COG1764	response to oxidative stress
AM425_RS06610	COG3111	PFAM Bacterial OB fold (BOF) protein
AM425_RS06620	COG2323	membrane
AM425_RS06630	COG0366	Alpha amylase catalytic
AM425_RS06640	COG3685	Protein conserved in bacteria
AM425_RS06655	COG3729	General stress protein
AM425_RS06660	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS06700	COG0488	(ABC) transporter
AM425_RS06715	COG1064	alcohol dehydrogenase
AM425_RS06720	COG0747	negative chemotaxis
AM425_RS06730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM425_RS06740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM425_RS06750	COG2814	Major facilitator Superfamily
AM425_RS06760	COG2326	polyphosphate kinase activity
AM425_RS06775	COG2864	formate dehydrogenase
AM425_RS06780	COG0437	4 iron, 4 sulfur cluster binding
AM425_RS06815	COG3485	protocatechuate 3,4-dioxygenase
AM425_RS06820	COG4829	muconolactone delta-isomerase
AM425_RS06825	COG4948	Mandelate Racemase Muconate Lactonizing
AM425_RS06830	COG1414	Transcriptional regulator
AM425_RS06850	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM425_RS06855	COG1140	nitrate reductase beta subunit
AM425_RS06860	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM425_RS06865	COG2181	nitrate reductase activity
AM425_RS06870	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AM425_RS06875	COG1178	ABC-type Fe3 transport system permease component
AM425_RS06880	COG1840	ABC-type Fe3 transport system, periplasmic component
AM425_RS06885	COG3842	ATPase activity
AM425_RS06890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM425_RS06905	COG2211	Major facilitator Superfamily
AM425_RS06935	COG0625	glutathione transferase activity
AM425_RS06945	COG1126	abc transporter atp-binding protein
AM425_RS06950	COG0765	amino acid transport
AM425_RS06960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM425_RS06965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM425_RS06970	COG1473	amidohydrolase
AM425_RS06975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM425_RS06980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM425_RS07005	COG4772	TonB-dependent receptor
AM425_RS07010	COG1228	amidohydrolase
AM425_RS07015	COG3691	Protein conserved in bacteria
AM425_RS07030	COG2130	NADP-dependent
AM425_RS07040	COG1247	-acetyltransferase
AM425_RS07045	COG3238	Protein conserved in bacteria
AM425_RS07055	COG0747	negative chemotaxis
AM425_RS07060	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS07090	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS07095	COG1177	transmembrane transport
AM425_RS07100	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM425_RS07105	COG3842	ATPase activity
AM425_RS07110	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM425_RS07115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM425_RS07120	COG1271	oxidase subunit
AM425_RS07125	COG1294	oxidase, subunit
AM425_RS07145	COG0826	peptidase U32
AM425_RS07155	COG1396	sequence-specific DNA binding
AM425_RS07160	COG3135	benzoate transporter
AM425_RS07165	COG3708	Transcriptional regulator
AM425_RS07165	COG2207	Transcriptional regulator
AM425_RS07170	COG0697	spore germination
AM425_RS07180	COG0500	methyltransferase
AM425_RS07185	COG1275	C4-dicarboxylate transporter malic acid transport protein
AM425_RS07190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM425_RS07195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM425_RS07210	COG2272	Belongs to the type-B carboxylesterase lipase family
AM425_RS07215	COG5383	Protein conserved in bacteria
AM425_RS07220	COG3485	protocatechuate 3,4-dioxygenase
AM425_RS07225	COG3485	protocatechuate 3,4-dioxygenase
AM425_RS07230	COG0583	DNA-binding transcription factor activity
AM425_RS07250	COG3038	cytochrome b561
AM425_RS07270	COG2814	Major facilitator Superfamily
AM425_RS07280	COG0673	inositol 2-dehydrogenase activity
AM425_RS07290	COG2723	6-phospho-beta-galactosidase activity
AM425_RS07325	COG4659	FMN binding
AM425_RS07335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM425_RS07350	COG0625	glutathione transferase activity
AM425_RS07355	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM425_RS07370	COG3895	Periplasmic Protein
AM425_RS07385	COG3706	GGDEF domain
AM425_RS07400	COG1566	PFAM secretion protein HlyD family protein
AM425_RS07405	COG1289	transmembrane transporter activity
AM425_RS07410	COG2032	superoxide dismutase activity
AM425_RS07415	COG4989	oxidoreductase activity
AM425_RS07420	COG3313	Fe-S protein
AM425_RS07425	COG1309	transcriptional regulator
AM425_RS07430	COG1902	pentaerythritol trinitrate reductase activity
AM425_RS07435	COG0346	lactoylglutathione lyase activity
AM425_RS07445	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM425_RS07450	COG0791	NLP P60 protein
AM425_RS07465	COG2814	Major facilitator Superfamily
AM425_RS07480	COG0583	DNA-binding transcription factor activity
AM425_RS07485	COG2814	Major facilitator Superfamily
AM425_RS07490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM425_RS07495	COG0307	riboflavin synthase, alpha
AM425_RS07550	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AM425_RS07580	COG1349	DNA-binding transcription factor activity
AM425_RS07585	COG0346	lactoylglutathione lyase activity
AM425_RS07610	COG0444	Belongs to the ABC transporter superfamily
AM425_RS07615	COG4608	Belongs to the ABC transporter superfamily
AM425_RS07645	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS07645	COG0604	alcohol dehydrogenase
AM425_RS07645	COG3321	synthase
AM425_RS07690	COG0402	S-adenosylhomocysteine deaminase activity
AM425_RS07715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM425_RS07720	COG0277	FAD linked oxidase domain protein
AM425_RS07735	COG2814	Major facilitator Superfamily
AM425_RS07780	COG0583	DNA-binding transcription factor activity
AM425_RS07790	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM425_RS07800	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM425_RS07805	COG2610	gluconate transmembrane transporter activity
AM425_RS07810	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS07845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM425_RS07870	COG0745	RESPONSE REGULATOR receiver
AM425_RS07875	COG5002	protein histidine kinase activity
AM425_RS07875	COG3850	Histidine kinase
AM425_RS07890	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AM425_RS07930	COG3088	subunit of a heme lyase
AM425_RS07930	COG4235	cytochrome complex assembly
AM425_RS07935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM425_RS07940	COG1138	Cytochrome C-type biogenesis protein
AM425_RS07955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM425_RS07960	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM425_RS07965	COG4133	protoheme IX ABC transporter activity
AM425_RS07995	COG1175	transmembrane transport
AM425_RS08010	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM425_RS08015	COG3383	formate dehydrogenase (NAD+) activity
AM425_RS08020	COG1473	amidohydrolase
AM425_RS08050	COG1126	abc transporter atp-binding protein
AM425_RS08055	COG0765	amino acid transport
AM425_RS08075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM425_RS08080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM425_RS08085	COG1120	ATPase activity
AM425_RS08090	COG4774	siderophore transport
AM425_RS08095	COG1116	anion transmembrane transporter activity
AM425_RS08100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM425_RS08120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM425_RS08125	COG0583	DNA-binding transcription factor activity
AM425_RS08145	COG2814	Major facilitator Superfamily
AM425_RS08180	COG1414	Transcriptional regulator
AM425_RS08185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM425_RS08190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM425_RS08195	COG1120	ATPase activity
AM425_RS08205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM425_RS08210	COG2271	Major facilitator Superfamily
AM425_RS08215	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AM425_RS08215	COG1082	Xylose isomerase domain protein TIM barrel
AM425_RS08220	COG1309	transcriptional regulator
AM425_RS08245	COG1376	ErfK ybiS ycfS ynhG family protein
AM425_RS08260	COG0719	Fe-S assembly protein
AM425_RS08265	COG0396	ATPase activity
AM425_RS08270	COG0719	Fe-S assembly protein
AM425_RS08275	COG0316	Belongs to the HesB IscA family
AM425_RS08290	COG1304	FMN binding
AM425_RS08315	COG0583	DNA-binding transcription factor activity
AM425_RS08325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM425_RS08330	COG1120	ATPase activity
AM425_RS08360	COG2261	transglycosylase associated protein
AM425_RS08365	COG2050	protein possibly involved in aromatic compounds catabolism
AM425_RS08370	COG0277	FAD linked oxidase domain protein
AM425_RS08370	COG0247	lactate metabolic process
AM425_RS08375	COG0628	permease
AM425_RS08385	COG0574	Belongs to the PEP-utilizing enzyme family
AM425_RS08385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM425_RS08395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM425_RS08400	COG4256	Hemin uptake protein
AM425_RS08410	COG0791	NLP P60 protein
AM425_RS08420	COG0386	Belongs to the glutathione peroxidase family
AM425_RS08440	COG0583	DNA-binding transcription factor activity
AM425_RS08460	COG0072	phenylalanine-tRNA ligase activity
AM425_RS08460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM425_RS08500	COG3137	Salt-induced outer membrane protein
AM425_RS08505	COG1105	Belongs to the carbohydrate kinase PfkB family
AM425_RS08515	COG3001	Fructosamine kinase
AM425_RS08525	COG2350	Protein conserved in bacteria
AM425_RS08535	COG2353	YceI-like domain
AM425_RS08555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM425_RS08565	COG0444	Belongs to the ABC transporter superfamily
AM425_RS08570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM425_RS08575	COG0601	transmembrane transport
AM425_RS08580	COG4166	transmembrane transport
AM425_RS08585	COG2095	MarC family integral membrane protein
AM425_RS08595	COG1454	alcohol dehydrogenase
AM425_RS08595	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS08600	COG1435	thymidine kinase activity
AM425_RS08605	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM425_RS08610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM425_RS08615	COG0745	RESPONSE REGULATOR receiver
AM425_RS08620	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM425_RS08630	COG0788	formyltetrahydrofolate deformylase activity
AM425_RS08660	COG1522	sequence-specific DNA binding
AM425_RS08670	COG2181	nitrate reductase activity
AM425_RS08675	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM425_RS08680	COG1140	nitrate reductase beta subunit
AM425_RS08685	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM425_RS08690	COG2223	nitrite transmembrane transporter activity
AM425_RS08695	COG3850	Histidine kinase
AM425_RS08700	COG2197	response regulator
AM425_RS08705	COG4932	domain protein
AM425_RS08710	COG0243	molybdopterin cofactor binding
AM425_RS08715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM425_RS08715	COG2146	nitrite reductase [NAD(P)H] activity
AM425_RS08720	COG1116	anion transmembrane transporter activity
AM425_RS08730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM425_RS08735	COG3707	response regulator
AM425_RS08740	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM425_RS08750	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM425_RS08755	COG4572	Cation transport regulator
AM425_RS08760	COG0387	Pfam Sodium calcium exchanger
AM425_RS08780	COG2890	protein-(glutamine-N5) methyltransferase activity
AM425_RS08815	COG0659	secondary active sulfate transmembrane transporter activity
AM425_RS08835	COG0012	GTP binding
AM425_RS08915	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM425_RS08975	COG2885	chlorophyll binding
AM425_RS09000	COG3122	Protein conserved in bacteria
AM425_RS09015	COG0583	DNA-binding transcription factor activity
AM425_RS09045	COG0583	DNA-binding transcription factor activity
AM425_RS09075	COG1882	Formate acetyltransferase
AM425_RS09090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM425_RS09095	COG0583	DNA-binding transcription factor activity
AM425_RS09135	COG2308	Evidence 4 Homologs of previously reported genes of
AM425_RS09150	COG4774	siderophore transport
AM425_RS09160	COG1619	proteins homologs of microcin C7 resistance protein MccF
AM425_RS09180	COG2719	SpoVR family
AM425_RS09210	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM425_RS09225	COG2894	cell division
AM425_RS09235	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM425_RS09245	COG3065	identical protein binding
AM425_RS09255	COG1199	ATP-dependent helicase activity
AM425_RS09260	COG0251	oxidation-reduction process
AM425_RS09280	COG1760	l-serine dehydratase
AM425_RS09285	COG2200	EAL domain
AM425_RS09290	COG1253	flavin adenine dinucleotide binding
AM425_RS09295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM425_RS09295	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS09300	COG3715	PTS system
AM425_RS09305	COG3716	PTS system mannose fructose sorbose family IID component
AM425_RS09320	COG2226	methyltransferase
AM425_RS09325	COG0768	penicillin binding
AM425_RS09375	COG1414	Transcriptional regulator
AM425_RS09385	COG2814	Major facilitator Superfamily
AM425_RS09405	COG1956	GAF domain-containing protein
AM425_RS09410	COG2995	paraquat-inducible protein a
AM425_RS09415	COG3008	intermembrane lipid transfer
AM425_RS09440	COG2990	Protein conserved in bacteria
AM425_RS09455	COG1276	copper resistance
AM425_RS09460	COG2372	response to copper ion
AM425_RS09470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM425_RS09475	COG1770	oligopeptidase
AM425_RS09480	COG2979	Protein of unknown function (DUF533)
AM425_RS09485	COG3141	response to X-ray
AM425_RS09495	COG0800	Aldolase
AM425_RS09500	COG0129	dihydroxy-acid dehydratase activity
AM425_RS09505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM425_RS09520	COG1737	Transcriptional regulator
AM425_RS09530	COG1560	Kdo2-lipid A biosynthetic process
AM425_RS09535	COG0739	heme binding
AM425_RS09540	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM425_RS09550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM425_RS09575	COG0494	nUDIX hydrolase
AM425_RS09585	COG1335	isochorismatase
AM425_RS09590	COG1801	Protein of unknown function DUF72
AM425_RS09595	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM425_RS09615	COG3102	Protein conserved in bacteria
AM425_RS09625	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AM425_RS09650	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM425_RS09660	COG1879	ABC-type sugar transport system periplasmic component
AM425_RS09670	COG1528	Iron-storage protein
AM425_RS09680	COG2211	Major facilitator Superfamily
AM425_RS09690	COG0477	Major facilitator Superfamily
AM425_RS09705	COG1528	Iron-storage protein
AM425_RS09715	COG0814	amino acid
AM425_RS09720	COG3012	SEC-C Motif Domain Protein
AM425_RS09720	COG3318	Belongs to the UPF0149 family
AM425_RS09755	COG2197	response regulator
AM425_RS09765	COG2197	response regulator
AM425_RS09770	COG1126	abc transporter atp-binding protein
AM425_RS09775	COG0765	amino acid transport
AM425_RS09785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM425_RS09790	COG0366	Alpha amylase catalytic
AM425_RS09820	COG2354	Protein conserved in bacteria
AM425_RS09825	COG0697	spore germination
AM425_RS09830	COG3727	T/G mismatch-specific endonuclease activity
AM425_RS09835	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM425_RS09840	COG1418	mRNA catabolic process
AM425_RS09855	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM425_RS09870	COG3344	reverse transcriptase
AM425_RS09925	COG4584	PFAM Integrase catalytic
AM425_RS09930	COG1484	DNA-dependent DNA replication
AM425_RS09980	COG0740	serine-type endopeptidase activity
AM425_RS09985	COG4695	Portal protein
AM425_RS09990	COG4626	Terminase
AM425_RS09990	COG1802	Transcriptional regulator
AM425_RS10030	COG3772	lysozyme
AM425_RS10050	COG1403	HNH endonuclease
AM425_RS10055	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM425_RS10165	COG0025	NhaP-type Na H and K H
AM425_RS10170	COG1309	transcriptional regulator
AM425_RS10175	COG0604	alcohol dehydrogenase
AM425_RS10195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM425_RS10205	COG0534	Mate efflux family protein
AM425_RS10225	COG3706	GGDEF domain
AM425_RS10250	COG3615	Tellurite resistance protein tehB
AM425_RS10255	COG3300	MHYT domain
AM425_RS10255	COG5001	Diguanylate cyclase
AM425_RS10270	COG0477	Major facilitator Superfamily
AM425_RS10275	COG0095	Lipoate-protein ligase
AM425_RS10280	COG0583	DNA-binding transcription factor activity
AM425_RS10285	COG1942	4-Oxalocrotonate Tautomerase
AM425_RS10295	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM425_RS10315	COG1289	transmembrane transporter activity
AM425_RS10330	COG2925	Exonuclease
AM425_RS10335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM425_RS10340	COG0640	Transcriptional regulator
AM425_RS10345	COG0531	amino acid
AM425_RS10355	COG0583	DNA-binding transcription factor activity
AM425_RS10360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM425_RS10390	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM425_RS10410	COG1215	transferase activity, transferring glycosyl groups
AM425_RS10505	COG1088	dTDP-glucose 4,6-dehydratase activity
AM425_RS10535	COG0438	transferase activity, transferring glycosyl groups
AM425_RS10545	COG1216	Glycosyl transferase, family 2
AM425_RS10545	COG1442	glycosyl transferase family 8
AM425_RS10610	COG1253	flavin adenine dinucleotide binding
AM425_RS10615	COG2982	Protein involved in outer membrane biogenesis
AM425_RS10630	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AM425_RS10635	COG0443	Heat shock 70 kDa protein
AM425_RS10640	COG5002	protein histidine kinase activity
AM425_RS10655	COG1301	dicarboxylic acid transport
AM425_RS10680	COG2205	protein histidine kinase activity
AM425_RS10685	COG0745	RESPONSE REGULATOR receiver
AM425_RS10690	COG0826	peptidase U32
AM425_RS10700	COG4608	Belongs to the ABC transporter superfamily
AM425_RS10705	COG0444	Belongs to the ABC transporter superfamily
AM425_RS10710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM425_RS10715	COG0601	transmembrane transport
AM425_RS10720	COG0747	negative chemotaxis
AM425_RS10725	COG4948	Mandelate Racemase Muconate Lactonizing
AM425_RS10730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM425_RS10740	COG1070	Carbohydrate kinase
AM425_RS10775	COG1830	Aldolase
AM425_RS10780	COG0351	phosphomethylpyrimidine kinase
AM425_RS10795	COG0583	DNA-binding transcription factor activity
AM425_RS10805	COG2252	PERMEase
AM425_RS10810	COG0583	DNA-binding transcription factor activity
AM425_RS10815	COG5455	response to cobalt ion
AM425_RS10835	COG4807	Protein conserved in bacteria
AM425_RS10845	COG3275	phosphorelay sensor kinase activity
AM425_RS10855	COG1174	glycine betaine transport
AM425_RS10860	COG1125	glycine betaine transport
AM425_RS10865	COG1174	glycine betaine transport
AM425_RS10870	COG1732	Glycine betaine
AM425_RS10875	COG1472	Belongs to the glycosyl hydrolase 3 family
AM425_RS10880	COG0277	FAD linked oxidase domain protein
AM425_RS10890	COG1686	Belongs to the peptidase S11 family
AM425_RS10900	COG0586	Pfam SNARE associated Golgi protein
AM425_RS10905	COG1538	Outer membrane efflux protein
AM425_RS10915	COG2723	6-phospho-beta-galactosidase activity
AM425_RS10930	COG3659	wide pore channel activity
AM425_RS10935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM425_RS10945	COG1346	cytolysis
AM425_RS10955	COG2949	membrane
AM425_RS10965	COG1129	ABC transporter
AM425_RS10980	COG2311	Membrane
AM425_RS10995	COG4771	TonB-dependent receptor
AM425_RS11005	COG0833	amino acid
AM425_RS11010	COG0583	DNA-binding transcription factor activity
AM425_RS11020	COG2855	membrane
AM425_RS11030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM425_RS11030	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM425_RS11030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM425_RS11035	COG1105	Belongs to the carbohydrate kinase PfkB family
AM425_RS11040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS11040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS11070	COG1312	Catalyzes the dehydration of D-mannonate
AM425_RS11075	COG0246	Mannitol dehydrogenase
AM425_RS11080	COG0523	cobalamin synthesis protein
AM425_RS11085	COG0671	phosphoesterase, PA-phosphatase related
AM425_RS11090	COG0791	NLP P60 protein
AM425_RS11095	COG2200	EAL domain
AM425_RS11100	COG4166	transmembrane transport
AM425_RS11105	COG4174	ABC transporter (Permease)
AM425_RS11110	COG4239	(ABC) transporter, permease
AM425_RS11115	COG4172	Belongs to the ABC transporter superfamily
AM425_RS11125	COG2814	Major facilitator Superfamily
AM425_RS11130	COG1187	pseudouridine synthase activity
AM425_RS11135	COG1061	Type III restriction enzyme res subunit
AM425_RS11155	COG0494	nUDIX hydrolase
AM425_RS11160	COG1349	DNA-binding transcription factor activity
AM425_RS11190	COG0628	permease
AM425_RS11205	COG0659	secondary active sulfate transmembrane transporter activity
AM425_RS11210	COG2239	Acts as a magnesium transporter
AM425_RS11215	COG4615	Cyclic peptide transporter
AM425_RS11220	COG3145	DNA-N1-methyladenine dioxygenase activity
AM425_RS11225	COG2169	Transcriptional regulator
AM425_RS11225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM425_RS11240	COG2198	Histidine kinase
AM425_RS11240	COG0642	Histidine kinase
AM425_RS11250	COG0784	Response regulator, receiver
AM425_RS11250	COG2205	protein histidine kinase activity
AM425_RS11280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM425_RS11290	COG0584	glycerophosphoryl diester phosphodiesterase
AM425_RS11295	COG2271	Major facilitator Superfamily
AM425_RS11300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM425_RS11310	COG0247	lactate metabolic process
AM425_RS11320	COG2271	Major facilitator Superfamily
AM425_RS11330	COG1414	Transcriptional regulator
AM425_RS11345	COG5464	transposase or invertase
AM425_RS11355	COG0318	PFAM AMP-dependent synthetase and ligase
AM425_RS11380	COG1169	isochorismate synthase
AM425_RS11385	COG2153	protein acetylation
AM425_RS11400	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM425_RS11405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM425_RS11415	COG0839	Belongs to the complex I subunit 6 family
AM425_RS11470	COG0583	DNA-binding transcription factor activity
AM425_RS11475	COG0436	Aminotransferase
AM425_RS11485	COG0490	domain, Protein
AM425_RS11485	COG0471	metal ion transport
AM425_RS11490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM425_RS11510	COG0857	belongs to the CobB CobQ family
AM425_RS11510	COG0280	phosphate acetyltransferase
AM425_RS11515	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM425_RS11520	COG0622	Phosphoesterase
AM425_RS11525	COG0625	glutathione transferase activity
AM425_RS11530	COG0625	glutathione transferase activity
AM425_RS11535	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM425_RS11540	COG1090	epimerase
AM425_RS11550	COG4598	ABC transporter
AM425_RS11555	COG4160	amino acid transport
AM425_RS11575	COG0163	prenyltransferase activity
AM425_RS11580	COG0833	amino acid
AM425_RS11585	COG3457	Alanine racemase
AM425_RS11590	COG0531	amino acid
AM425_RS11600	COG3829	transcription factor binding
AM425_RS11605	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM425_RS11610	COG1286	toxin biosynthetic process
AM425_RS11615	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM425_RS11620	COG0285	dihydrofolate synthase activity
AM425_RS11630	COG0586	Pfam SNARE associated Golgi protein
AM425_RS11640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM425_RS11660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM425_RS11675	COG3101	peptidyl-lysine hydroxylation
AM425_RS11680	COG0730	response to heat
AM425_RS11705	COG2062	phosphohistidine phosphatase, SixA
AM425_RS11720	COG3691	Protein conserved in bacteria
AM425_RS11730	COG2853	Lipoprotein
AM425_RS11735	COG2116	formate transmembrane transporter activity
AM425_RS11755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AM425_RS11775	COG3188	usher protein
AM425_RS11780	COG3121	Chaperone
AM425_RS11810	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM425_RS11815	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AM425_RS11820	COG2376	Dihydroxyacetone kinase
AM425_RS11835	COG3716	PTS system mannose fructose sorbose family IID component
AM425_RS11840	COG3715	PTS system
AM425_RS11845	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS11845	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM425_RS11850	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS11850	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM425_RS11890	COG1122	ATPase activity
AM425_RS11965	COG2171	N-acyltransferase activity
AM425_RS11970	COG4221	oxidoreductase activity
AM425_RS11975	COG2814	Major facilitator Superfamily
AM425_RS12005	COG0583	DNA-binding transcription factor activity
AM425_RS12010	COG0590	tRNA wobble adenosine to inosine editing
AM425_RS12015	COG2807	transmembrane transport
AM425_RS12025	COG0436	Aminotransferase
AM425_RS12035	COG3275	phosphorelay sensor kinase activity
AM425_RS12040	COG3279	Response regulator of the LytR AlgR family
AM425_RS12055	COG3961	Belongs to the TPP enzyme family
AM425_RS12060	COG0667	Aldo Keto reductase
AM425_RS12075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM425_RS12080	COG2199	diguanylate cyclase activity
AM425_RS12080	COG2200	EAL domain
AM425_RS12095	COG3415	Transposase
AM425_RS12100	COG3415	Transposase
AM425_RS12135	COG0583	DNA-binding transcription factor activity
AM425_RS12140	COG0385	Bile acid
AM425_RS12145	COG3530	Putative quorum-sensing-regulated virulence factor
AM425_RS12165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM425_RS12200	COG4319	ketosteroid isomerase
AM425_RS12210	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM425_RS12215	COG4208	sulfate ABC transporter
AM425_RS12220	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM425_RS12225	COG4150	thiosulfate binding
AM425_RS12235	COG2837	iron assimilation
AM425_RS12255	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM425_RS12345	COG4810	utilization protein
AM425_RS12355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM425_RS12360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM425_RS12365	COG5342	invasion associated locus B
AM425_RS12375	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM425_RS12375	COG0493	'glutamate synthase
AM425_RS12385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM425_RS12395	COG1393	Belongs to the ArsC family
AM425_RS12410	COG0400	carboxylic ester hydrolase activity
AM425_RS12415	COG1444	tRNA N-acetyltransferase activity
AM425_RS12420	COG2321	neutral zinc metallopeptidase
AM425_RS12435	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM425_RS12445	COG2716	regulation of RNA biosynthetic process
AM425_RS12450	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM425_RS12455	COG0628	permease
AM425_RS12460	COG4783	chaperone-mediated protein folding
AM425_RS12465	COG1393	Belongs to the ArsC family
AM425_RS12480	COG2233	PERMEase
AM425_RS12490	COG2723	6-phospho-beta-galactosidase activity
AM425_RS12505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM425_RS12520	COG2200	EAL domain
AM425_RS12540	COG0641	radical SAM
AM425_RS12545	COG3119	arylsulfatase activity
AM425_RS12555	COG0516	GMP reductase activity
AM425_RS12555	COG0517	IMP dehydrogenase activity
AM425_RS12565	COG1645	bacterial-type flagellum-dependent swarming motility
AM425_RS12585	COG2976	Protein conserved in bacteria
AM425_RS12620	COG4953	penicillin-binding protein 1C
AM425_RS12625	COG2373	Large extracellular alpha-helical protein
AM425_RS12630	COG2897	thiosulfate sulfurtransferase activity
AM425_RS12650	COG2975	iron-sulfur cluster assembly
AM425_RS12655	COG0633	Ferredoxin
AM425_RS12675	COG0822	iron-sulfur transferase activity
AM425_RS12705	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM425_RS12710	COG3683	transport system, periplasmic component
AM425_RS12715	COG3711	transcriptional antiterminator
AM425_RS12720	COG2814	Major facilitator Superfamily
AM425_RS12725	COG2017	converts alpha-aldose to the beta-anomer
AM425_RS12730	COG2814	Major facilitator Superfamily
AM425_RS12730	COG0477	Major facilitator Superfamily
AM425_RS12735	COG0457	Tetratricopeptide repeat
AM425_RS12740	COG1940	carbohydrate kinase activity
AM425_RS12745	COG2259	Doxx family
AM425_RS12760	COG1017	nitric oxide dioxygenase activity
AM425_RS12760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM425_RS12765	COG0347	Belongs to the P(II) protein family
AM425_RS12770	COG2204	response regulator
AM425_RS12775	COG3170	Tfp pilus assembly protein FimV
AM425_RS12780	COG2205	protein histidine kinase activity
AM425_RS12785	COG0047	phosphoribosylformylglycinamidine synthase activity
AM425_RS12785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM425_RS12800	COG0560	Phosphoserine phosphatase
AM425_RS12805	COG1737	Transcriptional regulator
AM425_RS12810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM425_RS12820	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM425_RS12840	COG0681	Belongs to the peptidase S26 family
AM425_RS12850	COG3086	response to oxidative stress
AM425_RS12855	COG3026	antisigma factor binding
AM425_RS12860	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AM425_RS12870	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM425_RS12880	COG0513	Belongs to the DEAD box helicase family
AM425_RS12895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM425_RS12900	COG3118	belongs to the thioredoxin family
AM425_RS12905	COG3148	PFAM DTW domain containing protein
AM425_RS12915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM425_RS12920	COG5544	Lipoprotein
AM425_RS12925	COG0477	Major facilitator Superfamily
AM425_RS12950	COG0542	response to heat
AM425_RS12965	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM425_RS12970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM425_RS12980	COG0077	Prephenate dehydratase
AM425_RS12980	COG1605	Chorismate mutase
AM425_RS12990	COG0287	Prephenate dehydrogenase
AM425_RS12990	COG1605	Chorismate mutase
AM425_RS12995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM425_RS13005	COG2199	diguanylate cyclase activity
AM425_RS13010	COG2885	chlorophyll binding
AM425_RS13045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM425_RS13050	COG4137	Cytochrome C assembly protein
AM425_RS13055	COG4536	flavin adenine dinucleotide binding
AM425_RS13075	COG0497	DNA recombination
AM425_RS13090	COG2867	negative regulation of translational initiation
AM425_RS13120	COG3708	Transcriptional regulator
AM425_RS13120	COG2207	Transcriptional regulator
AM425_RS13125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM425_RS13160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM425_RS13165	COG1126	abc transporter atp-binding protein
AM425_RS13170	COG0235	Class ii aldolase
AM425_RS13180	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS13200	COG3121	Chaperone
AM425_RS13215	COG3121	Chaperone
AM425_RS13220	COG3539	Fimbrial protein
AM425_RS13230	COG3284	Transcriptional regulator
AM425_RS13235	COG0583	DNA-binding transcription factor activity
AM425_RS13245	COG0640	Transcriptional regulator
AM425_RS13250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM425_RS13265	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM425_RS13290	COG4575	ribosome binding
AM425_RS13295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM425_RS13300	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM425_RS13305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM425_RS13315	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM425_RS13330	COG4176	ABC-type proline glycine betaine transport system permease component
AM425_RS13340	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM425_RS13350	COG1846	Transcriptional regulator
AM425_RS13355	COG1566	PFAM secretion protein HlyD family protein
AM425_RS13360	COG2814	Major facilitator Superfamily
AM425_RS13365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM425_RS13385	COG1238	metal cluster binding
AM425_RS13390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM425_RS13395	COG2823	Periplasmic or secreted lipoprotein
AM425_RS13425	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM425_RS13450	COG1546	Belongs to the CinA family
AM425_RS13455	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM425_RS13460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM425_RS13465	COG1121	(ABC) transporter
AM425_RS13475	COG2951	lytic endotransglycosylase activity
AM425_RS13480	COG3730	PTS system glucitol sorbitol-specific
AM425_RS13485	COG3732	PTS system glucitol sorbitol-specific
AM425_RS13495	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS13500	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS13505	COG1349	DNA-binding transcription factor activity
AM425_RS13535	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AM425_RS13540	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM425_RS13545	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM425_RS13550	COG1609	Transcriptional regulator
AM425_RS13555	COG1263	PTS System
AM425_RS13555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM425_RS13560	COG2723	6-phospho-beta-galactosidase activity
AM425_RS13570	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM425_RS13580	COG3260	NADH ubiquinone oxidoreductase 20
AM425_RS13585	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM425_RS13590	COG3261	NADH dehydrogenase
AM425_RS13590	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM425_RS13595	COG0650	Formate hydrogenlyase subunit 4
AM425_RS13600	COG0651	ATP synthesis coupled electron transport
AM425_RS13605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM425_RS13625	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM425_RS13630	COG0298	carbon dioxide binding
AM425_RS13635	COG0409	Hydrogenase expression formation protein
AM425_RS13640	COG0309	Hydrogenase expression formation protein (HypE)
AM425_RS13650	COG2723	6-phospho-beta-galactosidase activity
AM425_RS13660	COG4580	involved in the transport of maltose and maltodextrins
AM425_RS13670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM425_RS13675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM425_RS13680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM425_RS13685	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM425_RS13690	COG1940	carbohydrate kinase activity
AM425_RS13695	COG1609	Transcriptional regulator
AM425_RS13700	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM425_RS13705	COG1121	(ABC) transporter
AM425_RS13710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM425_RS13715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM425_RS13730	COG0679	Auxin Efflux Carrier
AM425_RS13750	COG3720	iron ion transport
AM425_RS13755	COG4558	Periplasmic binding protein
AM425_RS13760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM425_RS13805	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM425_RS13810	COG0163	prenyltransferase activity
AM425_RS13835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM425_RS13840	COG1388	LysM domain
AM425_RS13840	COG4942	peptidase
AM425_RS13900	COG2234	aminopeptidase activity
AM425_RS13915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM425_RS13920	COG1518	maintenance of DNA repeat elements
AM425_RS13935	COG1857	crispr-associated protein
AM425_RS13950	COG1203	CRISPR-associated helicase, Cas3
AM425_RS13970	COG0720	synthase
AM425_RS13975	COG0602	queuosine metabolic process
AM425_RS13995	COG3956	TIGRFAM MazG family protein
AM425_RS14000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM425_RS14010	COG3850	Histidine kinase
AM425_RS14010	COG2205	protein histidine kinase activity
AM425_RS14010	COG3437	response regulator, receiver
AM425_RS14010	COG4999	Histidine kinase
AM425_RS14020	COG1929	Belongs to the glycerate kinase type-1 family
AM425_RS14025	COG4948	Mandelate Racemase Muconate Lactonizing
AM425_RS14030	COG4948	Mandelate Racemase Muconate Lactonizing
AM425_RS14035	COG2271	Major facilitator Superfamily
AM425_RS14040	COG0716	FMN binding
AM425_RS14045	COG0564	pseudouridine synthase activity
AM425_RS14050	COG3098	single-species biofilm formation
AM425_RS14065	COG1611	Belongs to the LOG family
AM425_RS14070	COG0814	amino acid
AM425_RS14075	COG1760	l-serine dehydratase
AM425_RS14080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM425_RS14090	COG0477	Major facilitator Superfamily
AM425_RS14100	COG1464	Belongs to the NlpA lipoprotein family
AM425_RS14105	COG2011	ABC-type metal ion transport system permease component
AM425_RS14110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM425_RS14125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM425_RS14140	COG1454	alcohol dehydrogenase
AM425_RS14145	COG0235	Class ii aldolase
AM425_RS14150	COG0738	Major facilitator superfamily
AM425_RS14170	COG1349	DNA-binding transcription factor activity
AM425_RS14180	COG2363	Small membrane protein
AM425_RS14185	COG0583	DNA-binding transcription factor activity
AM425_RS14195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM425_RS14200	COG2166	iron-sulfur cluster assembly
AM425_RS14205	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM425_RS14210	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM425_RS14375	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM425_RS14405	COG1454	alcohol dehydrogenase
AM425_RS14405	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS14410	COG4656	Part of a membrane complex involved in electron transport
AM425_RS14440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM425_RS14445	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM425_RS14450	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM425_RS14450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM425_RS14460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM425_RS14465	COG1074	ATP-dependent DNA helicase activity
AM425_RS14470	COG1025	Belongs to the peptidase M16 family
AM425_RS14475	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM425_RS14480	COG4967	type IV pilus modification protein PilV
AM425_RS14490	COG4795	General secretion pathway protein
AM425_RS14495	COG2165	general secretion pathway protein
AM425_RS14525	COG0861	Integral membrane protein TerC family
AM425_RS14535	COG0667	Aldo Keto reductase
AM425_RS14560	COG1609	Transcriptional regulator
AM425_RS14570	COG2186	Transcriptional regulator
AM425_RS14575	COG2723	6-phospho-beta-galactosidase activity
AM425_RS14580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM425_RS14585	COG1609	Transcriptional regulator
AM425_RS14595	COG0583	DNA-binding transcription factor activity
AM425_RS14600	COG1794	racemase activity, acting on amino acids and derivatives
AM425_RS14605	COG1917	Cupin 2, conserved barrel domain protein
AM425_RS14610	COG1175	transmembrane transport
AM425_RS14615	COG0395	ABC-type sugar transport system, permease component
AM425_RS14620	COG3842	ATPase activity
AM425_RS14640	COG2223	nitrite transmembrane transporter activity
AM425_RS14650	COG2814	Major facilitator Superfamily
AM425_RS14655	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS14660	COG0823	Involved in the tonB-independent uptake of proteins
AM425_RS14670	COG0183	Belongs to the thiolase family
AM425_RS14685	COG0814	amino acid
AM425_RS14690	COG0667	Aldo Keto reductase
AM425_RS14750	COG0697	spore germination
AM425_RS14755	COG1846	Transcriptional regulator
AM425_RS14760	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM425_RS14770	COG0582	viral genome integration into host DNA
AM425_RS14775	COG4974	Belongs to the 'phage' integrase family
AM425_RS14785	COG3539	Fimbrial protein
AM425_RS14790	COG3121	Chaperone
AM425_RS14795	COG3188	usher protein
AM425_RS14800	COG3539	Fimbrial protein
AM425_RS14805	COG3539	Fimbrial protein
AM425_RS14810	COG3539	Fimbrial protein
AM425_RS14820	COG2388	GCN5-related N-acetyl-transferase
AM425_RS14825	COG3592	Divergent 4Fe-4S mono-cluster
AM425_RS14840	COG1289	transmembrane transporter activity
AM425_RS14845	COG1538	Outer membrane efflux protein
AM425_RS14860	COG1393	Belongs to the ArsC family
AM425_RS14865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM425_RS14905	COG0667	Aldo Keto reductase
AM425_RS14920	COG2814	Major facilitator Superfamily
AM425_RS14930	COG4942	peptidase
AM425_RS14955	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM425_RS14965	COG4974	Belongs to the 'phage' integrase family
AM425_RS14970	COG0716	FMN binding
AM425_RS14980	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM425_RS14990	COG1272	protein, Hemolysin III
AM425_RS15000	COG1737	Transcriptional regulator
AM425_RS15005	COG2723	6-phospho-beta-galactosidase activity
AM425_RS15025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM425_RS15030	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS15050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM425_RS15055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM425_RS15060	COG0006	proline dipeptidase activity
AM425_RS15080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM425_RS15085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM425_RS15100	COG2968	Membrane
AM425_RS15110	COG0668	transmembrane transport
AM425_RS15115	COG0191	fructose-bisphosphate aldolase activity
AM425_RS15130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM425_RS15135	COG0501	Belongs to the peptidase M48B family
AM425_RS15155	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AM425_RS15160	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS15190	COG1414	Transcriptional regulator
AM425_RS15195	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS15210	COG2146	nitrite reductase [NAD(P)H] activity
AM425_RS15250	COG2814	Major facilitator Superfamily
AM425_RS15260	COG2356	endonuclease I
AM425_RS15265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM425_RS15270	COG0189	ligase activity
AM425_RS15290	COG2805	Type II/IV secretion system protein
AM425_RS15295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM425_RS15300	COG0762	integral membrane protein
AM425_RS15315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM425_RS15325	COG3171	Protein conserved in bacteria
AM425_RS15335	COG1194	a g-specific adenine glycosylase
AM425_RS15350	COG2211	Major facilitator Superfamily
AM425_RS15355	COG1982	Orn Lys Arg decarboxylase major
AM425_RS15365	COG1811	Na channel or pump
AM425_RS15380	COG0626	cystathionine gamma-synthase activity
AM425_RS15385	COG0583	DNA-binding transcription factor activity
AM425_RS15405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM425_RS15410	COG0754	glutathionylspermidine amidase activity
AM425_RS15420	COG0625	glutathione transferase activity
AM425_RS15445	COG2211	Major facilitator Superfamily
AM425_RS15450	COG0848	biopolymer transport protein
AM425_RS15465	COG0626	cystathionine gamma-synthase activity
AM425_RS15470	COG0586	Pfam SNARE associated Golgi protein
AM425_RS15475	COG2207	Transcriptional regulator
AM425_RS15480	COG1979	alcohol dehydrogenase
AM425_RS15485	COG0656	L-ascorbic acid biosynthetic process
AM425_RS15495	COG1032	radical SAM domain protein
AM425_RS15500	COG2132	Multicopper oxidase
AM425_RS15505	COG0204	Acyl-transferase
AM425_RS15510	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM425_RS15515	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM425_RS15520	COG3111	PFAM Bacterial OB fold (BOF) protein
AM425_RS15530	COG0642	Histidine kinase
AM425_RS15535	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM425_RS15540	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM425_RS15550	COG3150	esterase
AM425_RS15555	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM425_RS15560	COG3151	Protein conserved in bacteria
AM425_RS15565	COG0494	nUDIX hydrolase
AM425_RS15580	COG0754	glutathionylspermidine amidase activity
AM425_RS15585	COG3384	dioxygenase
AM425_RS15600	COG2960	long-chain fatty acid transporting porin activity
AM425_RS15620	COG3025	triphosphatase activity
AM425_RS15625	COG4991	sh3 domain protein
AM425_RS15640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM425_RS15700	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM425_RS15705	COG0358	DNA primase activity
AM425_RS15710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM425_RS15870	COG4695	Portal protein
AM425_RS15905	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM425_RS15940	COG4974	Belongs to the 'phage' integrase family
AM425_RS15960	COG2197	response regulator
AM425_RS15965	COG2205	protein histidine kinase activity
AM425_RS15965	COG0784	Response regulator, receiver
AM425_RS15965	COG2198	Histidine kinase
AM425_RS15965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM425_RS15975	COG3247	response to pH
AM425_RS16050	COG2376	Dihydroxyacetone kinase
AM425_RS16055	COG1461	Dihydroxyacetone kinase
AM425_RS16070	COG2375	cellular response to nickel ion
AM425_RS16075	COG1695	Transcriptional regulator
AM425_RS16130	COG1902	pentaerythritol trinitrate reductase activity
AM425_RS16130	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM425_RS16150	COG1451	nucleotide metabolic process
AM425_RS16155	COG0673	inositol 2-dehydrogenase activity
AM425_RS16160	COG0861	Integral membrane protein TerC family
AM425_RS16175	COG2721	sulfolactate sulfo-lyase activity
AM425_RS16185	COG2271	Major facilitator Superfamily
AM425_RS16190	COG2186	Transcriptional regulator
AM425_RS16195	COG0586	Pfam SNARE associated Golgi protein
AM425_RS16205	COG1422	Protein of unknown function (DUF1090)
AM425_RS16210	COG4575	ribosome binding
AM425_RS16215	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM425_RS16225	COG2259	Doxx family
AM425_RS16230	COG0435	Glutathione S-transferase
AM425_RS16235	COG3152	Membrane
AM425_RS16240	COG0583	DNA-binding transcription factor activity
AM425_RS16245	COG1741	Belongs to the pirin family
AM425_RS16265	COG1929	Belongs to the glycerate kinase type-1 family
AM425_RS16270	COG2084	Dehydrogenase
AM425_RS16280	COG2271	Major facilitator Superfamily
AM425_RS16285	COG2721	sulfolactate sulfo-lyase activity
AM425_RS16290	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM425_RS16310	COG2823	Periplasmic or secreted lipoprotein
AM425_RS16315	COG0701	Predicted permease
AM425_RS16320	COG0702	epimerase
AM425_RS16325	COG0693	protein deglycase activity
AM425_RS16340	COG3153	acetyltransferase
AM425_RS16345	COG3154	lipid carrier protein
AM425_RS16350	COG0826	peptidase U32
AM425_RS16355	COG0826	peptidase U32
AM425_RS16360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM425_RS16365	COG0814	amino acid
AM425_RS16415	COG0195	Participates in both transcription termination and antitermination
AM425_RS16455	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM425_RS16465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM425_RS16470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM425_RS16480	COG1534	Rna-binding protein
AM425_RS16490	COG2027	D-alanyl-D-alanine carboxypeptidase
AM425_RS16500	COG0697	spore germination
AM425_RS16515	COG0142	geranyltranstransferase activity
AM425_RS16520	COG3423	Transcriptional regulator
AM425_RS16530	COG5007	Belongs to the BolA IbaG family
AM425_RS16535	COG3113	response to antibiotic
AM425_RS16540	COG2854	intermembrane phospholipid transfer
AM425_RS16545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM425_RS16550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM425_RS16555	COG1127	ABC transporter
AM425_RS16565	COG0530	calcium, potassium:sodium antiporter activity
AM425_RS16575	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM425_RS16580	COG3117	lipopolysaccharide transmembrane transporter activity
AM425_RS16585	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM425_RS16590	COG1137	ATPase activity
AM425_RS16595	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM425_RS16600	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM425_RS16605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS16615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS16620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM425_RS16625	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM425_RS16630	COG0784	Response regulator, receiver
AM425_RS16630	COG2198	Histidine kinase
AM425_RS16630	COG5002	protein histidine kinase activity
AM425_RS16635	COG1312	Catalyzes the dehydration of D-mannonate
AM425_RS16640	COG1063	alcohol dehydrogenase
AM425_RS16645	COG2271	Major facilitator Superfamily
AM425_RS16650	COG1242	4 iron, 4 sulfur cluster binding
AM425_RS16660	COG0067	glutamate synthase
AM425_RS16660	COG0069	glutamate synthase activity
AM425_RS16660	COG0070	glutamate synthase
AM425_RS16665	COG0493	'glutamate synthase
AM425_RS16675	COG2969	positive regulation of protein catabolic process
AM425_RS16680	COG0625	glutathione transferase activity
AM425_RS16700	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM425_RS16705	COG3105	Protein conserved in bacteria
AM425_RS16710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM425_RS16715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM425_RS16740	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM425_RS16745	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM425_RS16750	COG0471	metal ion transport
AM425_RS16785	COG2732	(Barnase) inhibitor
AM425_RS16790	COG1289	transmembrane transporter activity
AM425_RS16805	COG0583	DNA-binding transcription factor activity
AM425_RS16810	COG0312	modulator of DNA gyrase
AM425_RS16815	COG3164	Protein of unknown function
AM425_RS16820	COG1530	ribonuclease E activity
AM425_RS16830	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM425_RS16835	COG1792	Involved in formation and maintenance of cell shape
AM425_RS16840	COG1077	Cell shape determining protein MreB Mrl
AM425_RS16845	COG2199	diguanylate cyclase activity
AM425_RS16845	COG2200	EAL domain
AM425_RS16870	COG0511	ligase activity, forming carbon-carbon bonds
AM425_RS16875	COG0439	Biotin carboxylase
AM425_RS16880	COG3924	membrane
AM425_RS16885	COG4145	pantothenate transmembrane transporter activity
AM425_RS16910	COG1309	transcriptional regulator
AM425_RS16915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM425_RS16920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM425_RS16960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM425_RS16980	COG0551	DNA topoisomerase type I activity
AM425_RS16990	COG0758	DNA mediated transformation
AM425_RS17020	COG3036	rescue of stalled ribosome
AM425_RS17025	COG0789	Transcriptional regulator
AM425_RS17040	COG0202	RNA polymerase activity
AM425_RS17065	COG0201	protein transport
AM425_RS17130	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM425_RS17145	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM425_RS17170	COG0051	transcription antitermination factor activity, RNA binding
AM425_RS17230	COG2964	Protein conserved in bacteria
AM425_RS17235	COG0545	Peptidyl-prolyl cis-trans isomerase
AM425_RS17245	COG1047	Peptidyl-prolyl cis-trans
AM425_RS17250	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM425_RS17270	COG0488	(ABC) transporter
AM425_RS17280	COG0429	hydrolase of the alpha beta-hydrolase fold
AM425_RS17290	COG3954	Phosphoribulokinase
AM425_RS17295	COG1765	OsmC-like protein
AM425_RS17310	COG1289	transmembrane transporter activity
AM425_RS17315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM425_RS17340	COG0738	Major facilitator superfamily
AM425_RS17345	COG0402	S-adenosylhomocysteine deaminase activity
AM425_RS17350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM425_RS17375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM425_RS17380	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AM425_RS17385	COG3266	domain, Protein
AM425_RS17405	COG4796	Type ii and iii secretion system protein
AM425_RS17430	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM425_RS17435	COG0494	nUDIX hydrolase
AM425_RS17445	COG1011	Hydrolase
AM425_RS17450	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM425_RS17475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM425_RS17480	COG2183	response to ionizing radiation
AM425_RS17485	COG1918	ferrous iron import across plasma membrane
AM425_RS17510	COG1040	competence protein
AM425_RS17520	COG2610	gluconate transmembrane transporter activity
AM425_RS17525	COG1640	4-alpha-glucanotransferase
AM425_RS17530	COG0058	SHG alpha-glucan phosphorylase activity
AM425_RS17545	COG1349	DNA-binding transcription factor activity
AM425_RS17560	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM425_RS17575	COG0058	SHG alpha-glucan phosphorylase activity
AM425_RS17600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM425_RS17610	COG2610	gluconate transmembrane transporter activity
AM425_RS17615	COG3265	gluconokinase activity
AM425_RS17620	COG1609	Transcriptional regulator
AM425_RS17625	COG1741	Belongs to the pirin family
AM425_RS17630	COG0673	inositol 2-dehydrogenase activity
AM425_RS17640	COG1247	-acetyltransferase
AM425_RS17645	COG0405	Gamma-glutamyltransferase
AM425_RS17655	COG0584	glycerophosphoryl diester phosphodiesterase
AM425_RS17705	COG0559	Belongs to the binding-protein-dependent transport system permease family
AM425_RS17710	COG0683	leucine binding
AM425_RS17725	COG0683	leucine binding
AM425_RS17735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM425_RS17750	COG2177	Part of the ABC transporter FtsEX involved in
AM425_RS17755	COG2884	Cell division ATP-binding protein ftsE
AM425_RS17760	COG0552	protein localization to endoplasmic reticulum
AM425_RS17765	COG0742	ribosomal rna small subunit methyltransferase
AM425_RS17770	COG3776	membrane
AM425_RS17780	COG3714	YhhN family
AM425_RS17795	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM425_RS17805	COG0477	Major facilitator Superfamily
AM425_RS17810	COG0628	permease
AM425_RS17850	COG3479	Phenolic acid decarboxylase
AM425_RS17865	COG0747	negative chemotaxis
AM425_RS17870	COG0601	transmembrane transport
AM425_RS17875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM425_RS17885	COG1124	(ABC) transporter
AM425_RS17895	COG2239	Acts as a magnesium transporter
AM425_RS17900	COG2081	HI0933 family
AM425_RS17905	COG0306	phosphate transporter
AM425_RS17915	COG0589	response to stress
AM425_RS17940	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM425_RS17945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM425_RS17955	COG1454	alcohol dehydrogenase
AM425_RS17965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM425_RS17970	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS17975	COG0583	DNA-binding transcription factor activity
AM425_RS17980	COG1295	ribonuclease BN
AM425_RS17985	COG0477	Major facilitator Superfamily
AM425_RS17990	COG2982	Protein involved in outer membrane biogenesis
AM425_RS18005	COG0612	Peptidase, M16
AM425_RS18015	COG2200	EAL domain
AM425_RS18015	COG2199	diguanylate cyclase activity
AM425_RS18020	COG0457	Tetratricopeptide repeat
AM425_RS18020	COG3118	belongs to the thioredoxin family
AM425_RS18025	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM425_RS18030	COG1215	transferase activity, transferring glycosyl groups
AM425_RS18060	COG2194	sulfuric ester hydrolase activity
AM425_RS18075	COG0457	Tetratricopeptide repeat
AM425_RS18080	COG1215	transferase activity, transferring glycosyl groups
AM425_RS18090	COG2894	cell division
AM425_RS18105	COG4608	Belongs to the ABC transporter superfamily
AM425_RS18110	COG0444	Belongs to the ABC transporter superfamily
AM425_RS18115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM425_RS18120	COG0601	transmembrane transport
AM425_RS18125	COG0747	negative chemotaxis
AM425_RS18160	COG2223	nitrite transmembrane transporter activity
AM425_RS18165	COG5571	outer membrane autotransporter
AM425_RS18170	COG2818	Glycosylase
AM425_RS18175	COG0456	acetyltransferase
AM425_RS18180	COG0243	molybdopterin cofactor binding
AM425_RS18185	COG2885	chlorophyll binding
AM425_RS18190	COG1609	Transcriptional regulator
AM425_RS18200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM425_RS18225	COG2814	Major facilitator Superfamily
AM425_RS18230	COG2944	sequence-specific DNA binding
AM425_RS18235	COG1278	Cold shock
AM425_RS18270	COG3274	enterobacterial common antigen metabolic process
AM425_RS18275	COG4682	membrane
AM425_RS18280	COG4682	membrane
AM425_RS18300	COG4213	ABC transporter substrate-binding protein
AM425_RS18310	COG4214	carbohydrate transport
AM425_RS18315	COG1609	Transcriptional regulator
AM425_RS18315	COG2207	Transcriptional regulator
AM425_RS18320	COG2992	FlgJ-related protein
AM425_RS18330	COG0366	Alpha amylase catalytic
AM425_RS18335	COG3977	Valine--pyruvate aminotransferase
AM425_RS18340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM425_RS18345	COG1414	Transcriptional regulator
AM425_RS18350	COG3276	selenocysteine insertion sequence binding
AM425_RS18360	COG0625	glutathione transferase activity
AM425_RS18365	COG1566	PFAM secretion protein HlyD family protein
AM425_RS18385	COG3722	fumarate hydratase activity
AM425_RS18405	COG2186	Transcriptional regulator
AM425_RS18415	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM425_RS18435	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM425_RS18440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM425_RS18450	COG4942	peptidase
AM425_RS18455	COG2861	carbohydrate metabolic process
AM425_RS18460	COG0463	Glycosyl transferase, family 2
AM425_RS18470	COG0156	8-amino-7-oxononanoate synthase activity
AM425_RS18485	COG0859	PFAM glycosyl transferase family 9
AM425_RS18510	COG0859	PFAM glycosyl transferase family 9
AM425_RS18520	COG0438	transferase activity, transferring glycosyl groups
AM425_RS18525	COG1216	Glycosyl transferase, family 2
AM425_RS18530	COG1519	Transferase
AM425_RS18565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM425_RS18590	COG0842	Transport permease protein
AM425_RS18595	COG1131	(ABC) transporter
AM425_RS18615	COG1561	YicC-like family, N-terminal region
AM425_RS18625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM425_RS18625	COG2169	Transcriptional regulator
AM425_RS18635	COG2860	membrane
AM425_RS18655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM425_RS18660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM425_RS18665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM425_RS18670	COG1494	fructose-1,6-bisphosphatase
AM425_RS18680	COG3152	Membrane
AM425_RS18705	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM425_RS18725	COG0786	glutamate:sodium symporter activity
AM425_RS18730	COG2233	PERMEase
AM425_RS18735	COG2982	Protein involved in outer membrane biogenesis
AM425_RS18740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM425_RS18740	COG1263	PTS System
AM425_RS18745	COG1486	melibiose metabolic process
AM425_RS18755	COG1501	Belongs to the glycosyl hydrolase 31 family
AM425_RS18760	COG2211	Major facilitator Superfamily
AM425_RS18825	COG1064	alcohol dehydrogenase
AM425_RS18835	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AM425_RS18850	COG1464	Belongs to the NlpA lipoprotein family
AM425_RS18875	COG0583	DNA-binding transcription factor activity
AM425_RS18905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM425_RS18915	COG2814	Major facilitator Superfamily
AM425_RS18925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM425_RS18925	COG1263	PTS System
AM425_RS18930	COG0697	spore germination
AM425_RS18945	COG2828	Protein conserved in bacteria
AM425_RS18950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM425_RS18955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AM425_RS18960	COG0583	DNA-binding transcription factor activity
AM425_RS18965	COG3384	dioxygenase
AM425_RS18975	COG1609	Transcriptional regulator
AM425_RS18985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM425_RS18985	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM425_RS18990	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM425_RS18995	COG4580	involved in the transport of maltose and maltodextrins
AM425_RS19020	COG2188	Transcriptional regulator
AM425_RS19065	COG2271	Major facilitator Superfamily
AM425_RS19075	COG2197	response regulator
AM425_RS19080	COG0440	acetolactate synthase activity
AM425_RS19085	COG0028	Belongs to the TPP enzyme family
AM425_RS19110	COG2814	Major facilitator Superfamily
AM425_RS19115	COG0583	DNA-binding transcription factor activity
AM425_RS19120	COG2610	gluconate transmembrane transporter activity
AM425_RS19140	COG2149	membrane
AM425_RS19155	COG2188	Transcriptional regulator
AM425_RS19180	COG5645	(Lipo)protein
AM425_RS19185	COG0823	Involved in the tonB-independent uptake of proteins
AM425_RS19190	COG2271	Major facilitator Superfamily
AM425_RS19200	COG0800	Aldolase
AM425_RS19205	COG3734	2-keto-3-deoxy-galactonokinase
AM425_RS19210	COG2186	Transcriptional regulator
AM425_RS19225	COG0561	phosphatase activity
AM425_RS19230	COG0187	DNA topoisomerase II activity
AM425_RS19260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM425_RS19275	COG0582	viral genome integration into host DNA
AM425_RS19290	COG0717	Belongs to the dCTP deaminase family
AM425_RS19330	COG0454	-acetyltransferase
AM425_RS19350	COG2091	lysine biosynthetic process via aminoadipic acid
AM425_RS19355	COG0431	NADPH-dependent FMN reductase
AM425_RS19360	COG2252	PERMEase
AM425_RS19370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM425_RS19375	COG0363	glucosamine-6-phosphate deaminase activity
AM425_RS19380	COG2382	esterase
AM425_RS19395	COG0704	Plays a role in the regulation of phosphate uptake
AM425_RS19400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM425_RS19405	COG0581	inorganic phosphate transmembrane transporter activity
AM425_RS19410	COG0573	inorganic phosphate transmembrane transporter activity
AM425_RS19415	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM425_RS19420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM425_RS19470	COG3312	ion transport
AM425_RS19485	COG0716	FMN binding
AM425_RS19490	COG1522	sequence-specific DNA binding
AM425_RS19520	COG1129	ABC transporter
AM425_RS19525	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM425_RS19535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM425_RS19540	COG1609	Transcriptional regulator
AM425_RS19545	COG0477	Major facilitator Superfamily
AM425_RS19550	COG2186	Transcriptional regulator
AM425_RS19580	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM425_RS19590	COG3084	Protein conserved in bacteria
AM425_RS19595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM425_RS19605	COG0204	Acyl-transferase
AM425_RS19640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM425_RS19650	COG3852	Histidine kinase
AM425_RS19670	COG1011	Hydrolase
AM425_RS19685	COG0456	acetyltransferase
AM425_RS19695	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM425_RS19710	COG2864	formate dehydrogenase
AM425_RS19715	COG0437	4 iron, 4 sulfur cluster binding
AM425_RS19735	COG0205	6-phosphofructokinase activity
AM425_RS19795	COG2211	Major facilitator Superfamily
AM425_RS19805	COG1454	alcohol dehydrogenase
AM425_RS19810	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM425_RS19815	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM425_RS19820	COG1129	ABC transporter
AM425_RS19865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM425_RS19870	COG2258	MOSC domain
AM425_RS19875	COG2205	protein histidine kinase activity
AM425_RS19880	COG0745	RESPONSE REGULATOR receiver
AM425_RS19885	COG3678	ATP-independent chaperone mediated protein folding
AM425_RS19905	COG1575	Belongs to the MenA family. Type 1 subfamily
AM425_RS19920	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM425_RS19925	COG1609	Transcriptional regulator
AM425_RS19930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM425_RS19945	COG0626	cystathionine gamma-synthase activity
AM425_RS19950	COG0460	homoserine dehydrogenase
AM425_RS19950	COG0527	aspartate kinase activity
AM425_RS19960	COG0737	Belongs to the 5'-nucleotidase family
AM425_RS19970	COG0583	DNA-binding transcription factor activity
AM425_RS19980	COG0697	spore germination
AM425_RS19985	COG0371	Dehydrogenase
AM425_RS19995	COG2207	Transcriptional regulator
AM425_RS20000	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM425_RS20015	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM425_RS20040	COG0583	DNA-binding transcription factor activity
AM425_RS20115	COG3085	chromosome segregation
AM425_RS20135	COG3978	acetolactate synthase activity
AM425_RS20150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM425_RS20155	COG0583	DNA-binding transcription factor activity
AM425_RS20165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM425_RS20170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM425_RS20180	COG1811	Na channel or pump
AM425_RS20210	COG3118	belongs to the thioredoxin family
AM425_RS20220	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM425_RS20225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM425_RS20235	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM425_RS20240	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM425_RS20245	COG1088	dTDP-glucose 4,6-dehydratase activity
AM425_RS20250	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM425_RS20255	COG0456	acetyltransferase
AM425_RS20260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM425_RS20265	COG2244	polysaccharide biosynthetic process
AM425_RS20310	COG3071	HemY protein
AM425_RS20315	COG2959	enzyme of heme biosynthesis
AM425_RS20330	COG3072	Adenylate cyclase
AM425_RS20360	COG1011	Hydrolase
AM425_RS20365	COG0210	DNA helicase
AM425_RS20395	COG1280	lysine exporter protein (LysE YggA)
AM425_RS20405	COG1280	lysine exporter protein (LysE YggA)
AM425_RS20410	COG2267	carboxylic ester hydrolase activity
AM425_RS20415	COG0561	phosphatase activity
AM425_RS20420	COG0697	spore germination
AM425_RS20425	COG0583	DNA-binding transcription factor activity
AM425_RS20455	COG3165	ubiquinone biosynthetic process from chorismate
AM425_RS20475	COG0805	protein transport
AM425_RS20520	COG1739	Uncharacterized protein family UPF0029
AM425_RS20530	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AM425_RS20610	COG0250	Participates in transcription elongation, termination and antitermination
AM425_RS20650	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM425_RS20655	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM425_RS20665	COG3706	GGDEF domain
AM425_RS20685	COG2104	thiamine diphosphate biosynthetic process
AM425_RS20690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM425_RS20705	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AM425_RS20740	COG3678	ATP-independent chaperone mediated protein folding
AM425_RS20745	COG4191	Histidine kinase
AM425_RS20755	COG0151	Belongs to the GarS family
AM425_RS20800	COG0456	acetyltransferase
AM425_RS20810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM425_RS20840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM425_RS20895	COG0527	aspartate kinase activity
AM425_RS20915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM425_RS20925	COG0251	oxidation-reduction process
AM425_RS21000	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM425_RS21010	COG0534	Mate efflux family protein
AM425_RS21015	COG3237	CsbD-like
AM425_RS21020	COG0735	belongs to the Fur family
AM425_RS21030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM425_RS21045	COG0305	Participates in initiation and elongation during chromosome replication
AM425_RS21050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM425_RS21065	COG0432	Pfam Uncharacterised protein family UPF0047
AM425_RS21070	COG2315	Protein conserved in bacteria
AM425_RS21090	COG0741	lytic transglycosylase activity
AM425_RS21095	COG4771	TonB-dependent receptor
AM425_RS21115	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM425_RS21130	COG0483	inositol monophosphate 1-phosphatase activity
AM425_RS21135	COG1609	Transcriptional regulator
AM425_RS21140	COG1234	tRNA 3'-trailer cleavage
AM425_RS21175	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM425_RS21185	COG0789	Transcriptional regulator
AM425_RS21190	COG0625	glutathione transferase activity
AM425_RS21195	COG2252	PERMEase
AM425_RS21200	COG0025	NhaP-type Na H and K H
AM425_RS21205	COG0583	DNA-binding transcription factor activity
AM425_RS21210	COG1380	Effector of murein hydrolase LrgA
AM425_RS21215	COG1346	cytolysis
AM425_RS21220	COG3539	Fimbrial protein
AM425_RS21250	COG3162	membrane
AM425_RS21260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM425_RS21270	COG1301	dicarboxylic acid transport
AM425_RS21275	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM425_RS21310	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM425_RS21315	COG1129	ABC transporter
AM425_RS21320	COG4191	Histidine kinase
AM425_RS21320	COG0784	Response regulator, receiver
AM425_RS21330	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM425_RS21340	COG3454	Phosphonate metabolism
AM425_RS21345	COG4778	phosphonate C-P lyase system protein PhnL
AM425_RS21350	COG4107	phosphonate C-P lyase system protein PhnK
AM425_RS21355	COG3627	carbon phosphorus lyase activity
AM425_RS21360	COG3626	phosphonate metabolism
AM425_RS21365	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM425_RS21370	COG3624	Phosphonate C-P lyase system protein PhnG
AM425_RS21375	COG2188	Transcriptional regulator
AM425_RS21380	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AM425_RS21385	COG2824	Alkylphosphonate utilization operon protein PhnA
AM425_RS21400	COG2169	Transcriptional regulator
AM425_RS21410	COG1486	melibiose metabolic process
AM425_RS21445	COG0861	Integral membrane protein TerC family
AM425_RS21465	COG1215	transferase activity, transferring glycosyl groups
AM425_RS21470	COG1649	PFAM Uncharacterised BCR, COG1649
AM425_RS21470	COG0726	polysaccharide deacetylase
AM425_RS21475	COG0457	Tetratricopeptide repeat
AM425_RS21525	COG1309	transcriptional regulator
AM425_RS21540	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM425_RS21545	COG1027	Aspartate ammonia-lyase
AM425_RS21555	COG3030	protein affecting phage T7 exclusion by the F plasmid
AM425_RS21560	COG0531	amino acid
AM425_RS21625	COG1509	lysine 2,3-aminomutase activity
AM425_RS21640	COG5510	response to toxic substance
AM425_RS21645	COG2076	Multidrug Resistance protein
AM425_RS21665	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM425_RS21670	COG1053	succinate dehydrogenase
AM425_RS21685	COG3264	Mechanosensitive ion channel
AM425_RS21685	COG1511	domain protein
AM425_RS21710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM425_RS21735	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM425_RS21740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM425_RS21740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM425_RS21745	COG0802	atpase or kinase
AM425_RS21750	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM425_RS21770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM425_RS21775	COG0330	HflC and HflK could
AM425_RS21780	COG0330	HflC and HflK could
AM425_RS21790	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AM425_RS21805	COG0557	exoribonuclease II activity
AM425_RS21810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM425_RS21815	COG1960	acyl-CoA dehydrogenase activity
AM425_RS21825	COG3650	response to hydrogen peroxide
AM425_RS21830	COG1073	alpha beta
AM425_RS21890	COG2965	DNA replication, synthesis of RNA primer
AM425_RS21895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM425_RS21905	COG3061	Opacity-associated protein A
AM425_RS21910	COG0545	Peptidyl-prolyl cis-trans isomerase
AM425_RS21915	COG1113	amino acid transport
AM425_RS21925	COG0697	spore germination
AM425_RS21935	COG0702	epimerase
AM425_RS21940	COG1733	regulation of RNA biosynthetic process
AM425_RS21955	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM425_RS21970	COG1253	flavin adenine dinucleotide binding
AM425_RS21980	COG0729	surface antigen
AM425_RS21985	COG2911	Protein conserved in bacteria
AM425_RS21990	COG2105	PFAM AIG2 family protein
AM425_RS22010	COG1879	ABC-type sugar transport system periplasmic component
AM425_RS22015	COG1129	ABC transporter
AM425_RS22020	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM425_RS22025	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM425_RS22035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM425_RS22055	COG0312	modulator of DNA gyrase
AM425_RS22090	COG3964	amidohydrolase
AM425_RS22105	COG2706	6-phosphogluconolactonase activity
AM425_RS22110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS22110	COG3711	transcriptional antiterminator
AM425_RS22115	COG3077	Addiction module antitoxin, RelB DinJ family
AM425_RS22120	COG2026	Addiction module toxin, RelE StbE family
AM425_RS22125	COG0602	queuosine metabolic process
AM425_RS22145	COG1486	melibiose metabolic process
AM425_RS22150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM425_RS22155	COG0366	Alpha amylase catalytic
AM425_RS22160	COG1263	PTS System
AM425_RS22160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM425_RS22205	COG2731	YhcH YjgK YiaL family protein
AM425_RS22230	COG0525	valine-tRNA ligase activity
AM425_RS22235	COG2927	DNA polymerase III (CHI subunit)
AM425_RS22250	COG0795	lipopolysaccharide-transporting ATPase activity
AM425_RS22255	COG0795	lipopolysaccharide-transporting ATPase activity
AM425_RS22260	COG0433	COG0433 Predicted ATPase
AM425_RS22275	COG3718	enzyme involved in inositol metabolism
AM425_RS22295	COG1737	Transcriptional regulator
AM425_RS22295	COG0837	glucose binding
AM425_RS22300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM425_RS22305	COG3962	Belongs to the TPP enzyme family
AM425_RS22315	COG1082	Xylose isomerase domain protein TIM barrel
AM425_RS22330	COG3842	ATPase activity
AM425_RS22335	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM425_RS22340	COG0395	ABC-type sugar transport system, permease component
AM425_RS22345	COG1175	transmembrane transport
AM425_RS22350	COG1064	alcohol dehydrogenase
AM425_RS22355	COG0659	secondary active sulfate transmembrane transporter activity
AM425_RS22360	COG0288	reversible hydration of carbon dioxide
AM425_RS22375	COG0582	viral genome integration into host DNA
AM425_RS22380	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AM425_RS22400	COG1196	nuclear chromosome segregation
AM425_RS22405	COG1715	Restriction endonuclease
AM425_RS22510	COG3507	Belongs to the glycosyl hydrolase 43 family
AM425_RS22515	COG2211	Major facilitator Superfamily
AM425_RS22520	COG2115	Belongs to the xylose isomerase family
AM425_RS22525	COG4580	involved in the transport of maltose and maltodextrins
AM425_RS22530	COG3272	Protein of unknown function (DUF1722)
AM425_RS22550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM425_RS22565	COG0300	oxidoreductase activity
AM425_RS22575	COG0789	Transcriptional regulator
AM425_RS22580	COG3040	lipid binding
AM425_RS22590	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM425_RS22595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM425_RS22600	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM425_RS22605	COG1538	Outer membrane efflux protein
AM425_RS22610	COG0745	RESPONSE REGULATOR receiver
AM425_RS22615	COG5002	protein histidine kinase activity
AM425_RS22630	COG2850	peptidyl-arginine hydroxylation
AM425_RS22670	COG0842	Transport permease protein
AM425_RS22675	COG0842	Transport permease protein
AM425_RS22675	COG1129	ABC transporter
AM425_RS22680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM425_RS22690	COG1879	ABC-type sugar transport system periplasmic component
AM425_RS22695	COG1129	ABC transporter
AM425_RS22700	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM425_RS22710	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM425_RS22715	COG0583	DNA-binding transcription factor activity
AM425_RS22750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM425_RS22755	COG5457	Domain of unknown function (DUF1127)
AM425_RS22765	COG1566	PFAM secretion protein HlyD family protein
AM425_RS22780	COG1924	4 iron, 4 sulfur cluster binding
AM425_RS22785	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AM425_RS22800	COG2733	membrane
AM425_RS22810	COG2207	Transcriptional regulator
AM425_RS22810	COG1917	Cupin 2, conserved barrel domain protein
AM425_RS22820	COG5464	transposase or invertase
AM425_RS22825	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS22835	COG0523	cobalamin synthesis protein
AM425_RS22840	COG2879	small protein
AM425_RS22845	COG1966	Carbon starvation protein
AM425_RS22860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM425_RS22865	COG2368	4-hydroxyphenylacetate
AM425_RS22885	COG3971	2-oxopent-4-enoate hydratase activity
AM425_RS22895	COG3384	dioxygenase
AM425_RS22900	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS22910	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM425_RS22920	COG1846	Transcriptional regulator
AM425_RS22935	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM425_RS22935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM425_RS22950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM425_RS22955	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS22960	COG0531	amino acid
AM425_RS22980	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AM425_RS22995	COG3734	2-keto-3-deoxy-galactonokinase
AM425_RS23000	COG0800	Aldolase
AM425_RS23005	COG1737	Transcriptional regulator
AM425_RS23015	COG1214	PFAM Peptidase M22, glycoprotease
AM425_RS23015	COG0456	acetyltransferase
AM425_RS23020	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AM425_RS23020	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM425_RS23035	COG3715	PTS system
AM425_RS23040	COG3716	PTS system mannose fructose sorbose family IID component
AM425_RS23045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM425_RS23055	COG5464	transposase or invertase
AM425_RS23070	COG1484	DNA-dependent DNA replication
AM425_RS23085	COG2966	Psort location CytoplasmicMembrane, score
AM425_RS23105	COG2197	response regulator
AM425_RS23110	COG2197	response regulator
AM425_RS23115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM425_RS23120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM425_RS23120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM425_RS23125	COG4114	ferric iron reductase
AM425_RS23130	COG3706	GGDEF domain
AM425_RS23160	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AM425_RS23165	COG0456	acetyltransferase
AM425_RS23170	COG1011	Hydrolase
AM425_RS23180	COG2823	Periplasmic or secreted lipoprotein
AM425_RS23190	COG4667	esterase of the alpha-beta hydrolase superfamily
AM425_RS23195	COG0084	hydrolase, TatD family'
AM425_RS23200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM425_RS23230	COG3726	membrane protein affecting hemolysin expression
AM425_RS23240	COG0560	Phosphoserine phosphatase
AM425_RS23245	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AM425_RS23255	COG0488	(ABC) transporter
AM425_RS23260	COG0741	lytic transglycosylase activity
AM425_RS23280	COG3708	Transcriptional regulator
AM425_RS23280	COG2207	Transcriptional regulator
AM425_RS23285	COG3045	CreA protein
AM425_RS23290	COG0745	RESPONSE REGULATOR receiver
AM425_RS23295	COG2205	protein histidine kinase activity
AM425_RS23300	COG4452	Inner membrane protein CreD
AM425_RS23305	COG0745	RESPONSE REGULATOR receiver
AM425_RS23320	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM425_RS23330	COG0460	homoserine dehydrogenase
AM425_RS23330	COG0527	aspartate kinase activity
AM425_RS23340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM425_RS23355	COG1115	amino acid carrier protein
AM425_RS23360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM425_RS23365	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM425_RS23370	COG0477	Major facilitator Superfamily
AM425_RS23375	COG1584	GPR1 FUN34 yaaH family protein
AM425_RS23380	COG4735	regulation of single-species biofilm formation
AM425_RS23405	COG0583	DNA-binding transcription factor activity
AM425_RS23420	COG0196	riboflavin kinase activity
AM425_RS23435	COG1047	Peptidyl-prolyl cis-trans
AM425_RS23460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM425_RS23530	COG0505	Belongs to the CarA family
AM425_RS23585	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM425_RS23595	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM425_RS23600	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM425_RS23615	COG3493	citrate carrier protein
AM425_RS23630	COG0564	pseudouridine synthase activity
AM425_RS23640	COG0417	DNA replication proofreading
AM425_RS23645	COG0235	Class ii aldolase
AM425_RS23665	COG0586	Pfam SNARE associated Golgi protein
AM425_RS23675	COG1178	ABC-type Fe3 transport system permease component
AM425_RS23695	COG2814	Major facilitator Superfamily
AM425_RS23700	COG2271	Major facilitator Superfamily
AM425_RS23705	COG0583	DNA-binding transcription factor activity
AM425_RS23715	COG0738	Major facilitator superfamily
AM425_RS23765	COG0028	Belongs to the TPP enzyme family
AM425_RS23775	COG1609	Transcriptional regulator
AM425_RS23795	COG0768	penicillin binding
AM425_RS23800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM425_RS23805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM425_RS23820	COG0772	Belongs to the SEDS family
AM425_RS23845	COG0849	cell division
AM425_RS23850	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM425_RS23870	COG0494	nUDIX hydrolase
AM425_RS23895	COG1459	type II secretion system
AM425_RS23900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM425_RS23905	COG4969	Belongs to the N-Me-Phe pilin family
AM425_RS23915	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM425_RS23920	COG3725	Membrane protein required for beta-lactamase induction
AM425_RS23925	COG3940	Belongs to the glycosyl hydrolase 43 family
AM425_RS23930	COG2211	Major facilitator Superfamily
AM425_RS23935	COG1113	amino acid transport
AM425_RS23940	COG2186	Transcriptional regulator
AM425_RS23945	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM425_RS23950	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM425_RS23955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM425_RS23970	COG3064	Membrane
AM425_RS24020	COG2132	Multicopper oxidase
AM425_RS24025	COG4993	Dehydrogenase
AM425_RS24035	COG0288	reversible hydration of carbon dioxide
AM425_RS24040	COG1131	(ABC) transporter
AM425_RS24045	COG0842	Transport permease protein
AM425_RS24050	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS24055	COG0726	polysaccharide deacetylase
AM425_RS24075	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM425_RS24080	COG0617	tRNA 3'-terminal CCA addition
AM425_RS24100	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM425_RS24105	COG1643	Atp-dependent helicase
AM425_RS24195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM425_RS24200	COG4774	siderophore transport
AM425_RS24205	COG1120	ATPase activity
AM425_RS24210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM425_RS24215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM425_RS24235	COG2860	membrane
AM425_RS24255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM425_RS24260	COG3835	regulator
AM425_RS24275	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AM425_RS24280	COG0024	Methionine aminopeptidase
AM425_RS24305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM425_RS24320	COG0575	Belongs to the CDS family
AM425_RS24325	COG0750	zinc metalloprotease
AM425_RS24335	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AM425_RS24365	COG0587	DNA-directed DNA polymerase activity
AM425_RS24375	COG1982	Orn Lys Arg decarboxylase major
AM425_RS24380	COG0346	lactoylglutathione lyase activity
AM425_RS24390	COG4568	rho-dependent transcription termination
AM425_RS24405	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM425_RS24410	COG3015	lipoprotein NlpE involved in copper resistance
AM425_RS24415	COG0791	NLP P60 protein
AM425_RS24425	COG1720	tRNA m6t6A37 methyltransferase activity
AM425_RS24435	COG1464	Belongs to the NlpA lipoprotein family
AM425_RS24440	COG2011	ABC-type metal ion transport system permease component
AM425_RS24450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM425_RS24490	COG0656	L-ascorbic acid biosynthetic process
AM425_RS24495	COG0583	DNA-binding transcription factor activity
AM425_RS24500	COG2814	Major facilitator Superfamily
AM425_RS24510	COG2226	methyltransferase
AM425_RS24515	COG1388	LysM domain
AM425_RS24515	COG0741	lytic transglycosylase activity
AM425_RS24525	COG2226	methyltransferase
AM425_RS24535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM425_RS24545	COG0583	DNA-binding transcription factor activity
AM425_RS24555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM425_RS24560	COG1960	acyl-CoA dehydrogenase activity
AM425_RS24570	COG0121	glutamine amidotransferase
AM425_RS24575	COG3034	peptidoglycan biosynthetic process
AM425_RS24595	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM425_RS24600	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM425_RS24615	COG2991	Protein conserved in bacteria
AM425_RS24630	COG0454	-acetyltransferase
AM425_RS24635	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM425_RS24655	COG1802	Transcriptional regulator
AM425_RS24660	COG1113	amino acid transport
AM425_RS24665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM425_RS24670	COG1012	belongs to the aldehyde dehydrogenase family
AM425_RS24675	COG0579	oxidoreductase
AM425_RS24695	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AM425_RS24700	COG0625	glutathione transferase activity
AM425_RS24705	COG3775	system Galactitol-specific IIC component
AM425_RS24710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM425_RS24715	COG1028	Short-chain dehydrogenase reductase Sdr
AM425_RS24720	COG1070	Carbohydrate kinase
AM425_RS24745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM425_RS24750	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM425_RS24755	COG0022	dehydrogenase e1 component
AM425_RS24760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM425_RS24765	COG2909	trisaccharide binding
AM425_RS24795	COG3188	usher protein
AM425_RS24800	COG3121	Chaperone
AM425_RS24835	COG0582	viral genome integration into host DNA
AM425_RS24860	COG0791	NLP P60 protein
AM425_RS24890	COG3639	organic phosphonate transmembrane transporter activity
AM425_RS24900	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM425_RS24925	COG3188	usher protein
AM425_RS24940	COG0765	amino acid transport
AM425_RS24945	COG4597	amino acid ABC transporter
AM425_RS24950	COG1126	abc transporter atp-binding protein
AM425_RS24955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM425_RS24990	COG4302	ethanolamine ammonia-lyase activity
AM425_RS24995	COG4303	Ethanolamine ammonia lyase large subunit
AM425_RS25005	COG0833	amino acid
AM425_RS25010	COG2040	homocysteine
AM425_RS25015	COG4521	taurine ABC transporter
AM425_RS25020	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AM425_RS25025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM425_RS25030	COG2175	clavaminate synthase activity
AM425_RS25040	COG1943	Transposase
AM425_RS25045	COG0113	porphobilinogen synthase activity
AM425_RS25050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM425_RS25055	COG1335	isochorismatase
AM425_RS25060	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM425_RS25100	COG1785	Belongs to the alkaline phosphatase family
AM425_RS25110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM425_RS25120	COG3416	Protein conserved in bacteria
AM425_RS25125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM425_RS25135	COG4126	flavin adenine dinucleotide binding
AM425_RS25150	COG1940	carbohydrate kinase activity
AM425_RS25155	COG0419	ATPase involved in DNA repair
AM425_RS25160	COG0420	3'-5' exonuclease activity
AM425_RS25185	COG0366	Alpha amylase catalytic
AM425_RS25190	COG0583	DNA-binding transcription factor activity
AM425_RS25195	COG1335	isochorismatase
AM425_RS25205	COG1228	amidohydrolase
AM425_RS25215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM425_RS25230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM425_RS25235	COG0450	alkyl hydroperoxide reductase
AM425_RS25255	COG1862	Preprotein translocase
AM425_RS25260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM425_RS25265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM425_RS25285	COG4238	major outer membrane lipoprotein
AM425_RS25295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM425_RS25295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM425_RS25315	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM425_RS25320	COG0667	Aldo Keto reductase
AM425_RS25330	COG0142	geranyltranstransferase activity
AM425_RS25350	COG0693	protein deglycase activity
AM425_RS25355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM425_RS25365	COG2814	Major facilitator Superfamily
AM425_RS25370	COG0673	inositol 2-dehydrogenase activity
AM425_RS25385	COG1053	succinate dehydrogenase
AM425_RS25395	COG1053	succinate dehydrogenase
AM425_RS25400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM425_RS25405	COG1414	Transcriptional regulator
AM425_RS25420	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM425_RS25425	COG1845	cytochrome c oxidase, subunit III
AM425_RS25430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM425_RS25435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM425_RS25440	COG2223	nitrite transmembrane transporter activity
AM425_RS25445	COG3056	Lipoprotein
AM425_RS25450	COG0271	Belongs to the BolA IbaG family
AM425_RS25480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM425_RS25485	COG0776	regulation of translation
AM425_RS25490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM425_RS25495	COG1555	photosystem II stabilization
AM425_RS25500	COG0824	Thioesterase
AM425_RS25510	COG4533	DNA binding
AM425_RS25525	COG1522	sequence-specific DNA binding
AM425_RS25530	COG1132	(ABC) transporter
AM425_RS25535	COG1132	(ABC) transporter
AM425_RS25540	COG0347	Belongs to the P(II) protein family
AM425_RS25545	COG0004	ammonium transporteR
AM425_RS25550	COG1946	Acyl-CoA thioesterase
AM425_RS25555	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AM425_RS25560	COG3695	enzyme binding
AM425_RS25590	COG2364	Membrane
AM425_RS25605	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM425_RS25615	COG2182	Extracellular solute-binding protein
AM425_RS25620	COG1175	transmembrane transport
AM425_RS25625	COG3833	ABC-type maltose transport systems, permease component
AM425_RS25630	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AM425_RS25635	COG1874	Beta-galactosidase
AM425_RS25680	COG0110	maltose O-acetyltransferase activity
AM425_RS25695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM425_RS25700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM425_RS25705	COG1309	transcriptional regulator
AM425_RS25710	COG1196	nuclear chromosome segregation
AM425_RS25710	COG3264	Mechanosensitive ion channel
AM425_RS25715	COG5464	transposase or invertase
AM425_RS25725	COG3923	Primosomal replication protein n
AM425_RS25730	COG2832	Protein of unknown function (DUF454)
AM425_RS25770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM425_RS25775	COG4651	solute:proton antiporter activity
AM425_RS25775	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM425_RS25780	COG2223	nitrite transmembrane transporter activity
AM425_RS25790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM425_RS25795	COG3735	TraB family
AM425_RS25810	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM425_RS25815	COG0330	HflC and HflK could
AM425_RS25820	COG4619	ABC transporter
AM425_RS25825	COG0390	transport system, permease component
AM425_RS25835	COG3118	belongs to the thioredoxin family
AM425_RS25840	COG0300	oxidoreductase activity
AM425_RS25845	COG2755	lipolytic protein G-D-S-L family
AM425_RS25850	COG4181	ATPase activity
AM425_RS25855	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM425_RS25870	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM425_RS25875	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM425_RS25895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM425_RS25905	COG2501	S4 domain
AM425_RS25965	COG3539	Fimbrial protein
AM425_RS25970	COG3121	Chaperone
AM425_RS25975	COG3188	usher protein
AM425_RS25990	COG1560	Kdo2-lipid A biosynthetic process
AM425_RS26000	COG3710	Transcriptional regulator
AM425_RS26005	COG0531	amino acid
AM425_RS26010	COG1982	Orn Lys Arg decarboxylase major
AM425_RS26015	COG3104	oligopeptide transport
AM425_RS26050	COG0673	inositol 2-dehydrogenase activity
AM425_RS26065	COG1129	ABC transporter
AM425_RS26070	COG4211	Belongs to the binding-protein-dependent transport system permease family
AM425_RS26115	COG1566	PFAM secretion protein HlyD family protein
AM425_RS26120	COG1120	ATPase activity
AM425_RS26125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM425_RS26270	COG5654	RES domain protein
AM425_RS26275	COG5642	Protein of unknown function (DUF2384)
AM425_RS26295	COG3344	reverse transcriptase
AM425_RS26560	COG0633	Ferredoxin
AM425_RS26870	COG0210	DNA helicase
AM425_RS26975	COG3344	reverse transcriptase
AM425_RS27065	COG1358	cellular component organization or biogenesis
AM425_RS27170	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM425_RS27185	COG2801	Transposase and inactivated derivatives
AM425_RS27225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM425_RS27235	COG0675	Transposase, IS605 OrfB family
AM425_RS27370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM425_RS27475	COG4626	Terminase
AM425_RS27475	COG1802	Transcriptional regulator
AM425_RS27490	COG0616	signal peptide processing
AM425_RS27690	COG0328	RNA-DNA hybrid ribonuclease activity
AM425_RS27725	COG0237	dephospho-CoA kinase activity
AM425_RS27740	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AM425_RS27750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM425_RS27755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM425_RS27820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM425_RS27830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM425_RS27850	COG1278	Cold shock
AM425_RS27905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM425_RS27910	COG1702	phosphate starvation-inducible protein PhoH
AM425_RS28045	COG3941	tape measure
AM425_RS28135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM425_RS28140	COG1475	DNA binding
AM425_RS28145	COG1475	DNA binding
AM425_RS28290	COG3436	PFAM IS66 Orf2 family protein
AM425_RS28295	COG4372	Transposase
AM425_RS28600	COG4644	lycopene metabolic process
AM425_RS28620	COG0697	spore germination
AM425_RS28675	COG1660	Displays ATPase and GTPase activities
AM425_RS28900	COG3344	reverse transcriptase
AM425_RS28940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM425_RS28940	COG0426	domain, Protein
AM425_RS29120	COG3173	Aminoglycoside phosphotransferase