locus-tag	class	description
AM447_RS00005	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS00005	COG2030	dehydratase
AM447_RS00030	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS00035	COG2207	Transcriptional regulator
AM447_RS00040	COG3784	Protein of unknown function (DUF1318)
AM447_RS00050	COG2911	Protein conserved in bacteria
AM447_RS00055	COG0586	Pfam SNARE associated Golgi protein
AM447_RS00060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM447_RS00065	COG3187	Heat shock protein
AM447_RS00070	COG3042	response to heat
AM447_RS00080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM447_RS00080	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM447_RS00080	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM447_RS00080	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM447_RS00085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM447_RS00095	COG0589	response to stress
AM447_RS00105	COG0513	Belongs to the DEAD box helicase family
AM447_RS00130	COG1349	DNA-binding transcription factor activity
AM447_RS00135	COG0673	inositol 2-dehydrogenase activity
AM447_RS00150	COG1113	amino acid transport
AM447_RS00155	COG1522	sequence-specific DNA binding
AM447_RS00165	COG1448	Aminotransferase
AM447_RS00170	COG2011	ABC-type metal ion transport system permease component
AM447_RS00180	COG1464	Belongs to the NlpA lipoprotein family
AM447_RS00185	COG0436	Aminotransferase
AM447_RS00190	COG0604	alcohol dehydrogenase
AM447_RS00215	COG0583	DNA-binding transcription factor activity
AM447_RS00235	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS00240	COG1309	transcriptional regulator
AM447_RS00245	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS00355	COG2885	chlorophyll binding
AM447_RS00380	COG0693	protein deglycase activity
AM447_RS00385	COG1078	dGTPase activity
AM447_RS00390	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS00395	COG0583	DNA-binding transcription factor activity
AM447_RS00465	COG0784	Response regulator, receiver
AM447_RS00465	COG2205	protein histidine kinase activity
AM447_RS00465	COG5002	protein histidine kinase activity
AM447_RS00470	COG3250	beta-galactosidase activity
AM447_RS00475	COG0656	L-ascorbic acid biosynthetic process
AM447_RS00505	COG4166	transmembrane transport
AM447_RS00510	COG2866	Carboxypeptidase
AM447_RS00515	COG4948	Mandelate Racemase Muconate Lactonizing
AM447_RS00520	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM447_RS00525	COG3180	Ammonia monooxygenase
AM447_RS00535	COG1486	melibiose metabolic process
AM447_RS00540	COG0583	DNA-binding transcription factor activity
AM447_RS00550	COG3106	COG3106 Predicted ATPase
AM447_RS00560	COG1983	PspC domain protein
AM447_RS00570	COG1842	Phage shock protein A
AM447_RS00575	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM447_RS00585	COG1473	amidohydrolase
AM447_RS00600	COG0702	epimerase
AM447_RS00615	COG4171	peptide transport system, permease
AM447_RS00630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM447_RS00640	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM447_RS00645	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM447_RS00645	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM447_RS00660	COG1349	DNA-binding transcription factor activity
AM447_RS00670	COG0023	Translation Initiation Factor
AM447_RS00680	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM447_RS00685	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM447_RS00690	COG0671	phosphoesterase, PA-phosphatase related
AM447_RS00700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM447_RS00735	COG0616	signal peptide processing
AM447_RS00745	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS00750	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM447_RS00780	COG0583	DNA-binding transcription factor activity
AM447_RS00790	COG0009	L-threonylcarbamoyladenylate synthase
AM447_RS00800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM447_RS00805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM447_RS00805	COG0512	Glutamine amidotransferase of anthranilate synthase
AM447_RS00810	COG0134	indole-3-glycerol-phosphate synthase activity
AM447_RS00810	COG0135	phosphoribosylanthranilate isomerase activity
AM447_RS00865	COG4774	siderophore transport
AM447_RS00875	COG3047	cAMP biosynthetic process
AM447_RS00880	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM447_RS00910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM447_RS00915	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS00920	COG1988	membrane-bound metal-dependent
AM447_RS00925	COG1823	symporter activity
AM447_RS00935	COG0753	catalase activity
AM447_RS00945	COG1486	melibiose metabolic process
AM447_RS00950	COG1917	Cupin 2, conserved barrel domain protein
AM447_RS00950	COG2169	Transcriptional regulator
AM447_RS00955	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM447_RS00960	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS00965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS00970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM447_RS00980	COG0322	excinuclease ABC activity
AM447_RS00985	COG3678	ATP-independent chaperone mediated protein folding
AM447_RS00995	COG3724	N-succinylarginine dihydrolase activity
AM447_RS01005	COG3138	arginine N-succinyltransferase
AM447_RS01015	COG0708	Exodeoxyribonuclease III
AM447_RS01020	COG0398	Pfam SNARE associated Golgi protein
AM447_RS01025	COG0398	Pfam SNARE associated Golgi protein
AM447_RS01030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM447_RS01035	COG4134	Bacterial extracellular solute-binding protein
AM447_RS01040	COG4135	transport system, permease component
AM447_RS01045	COG4136	ATPase activity
AM447_RS01050	COG2897	thiosulfate sulfurtransferase activity
AM447_RS01055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM447_RS01060	COG0494	nUDIX hydrolase
AM447_RS01065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM447_RS01070	COG3321	synthase
AM447_RS01070	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS01070	COG0604	alcohol dehydrogenase
AM447_RS01075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM447_RS01080	COG0709	Synthesizes selenophosphate from selenide and ATP
AM447_RS01095	COG0778	Nitroreductase
AM447_RS01100	COG0616	signal peptide processing
AM447_RS01105	COG0252	asparaginase activity
AM447_RS01110	COG1335	isochorismatase
AM447_RS01125	COG3139	Protein of unknown function (DUF1315)
AM447_RS01145	COG0656	L-ascorbic acid biosynthetic process
AM447_RS01150	COG3713	MltA-interacting MipA family protein
AM447_RS01155	COG2766	serine protein kinase
AM447_RS01170	COG0386	Belongs to the glutathione peroxidase family
AM447_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS01195	COG0583	DNA-binding transcription factor activity
AM447_RS01200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM447_RS01205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM447_RS01210	COG3344	reverse transcriptase
AM447_RS01225	COG0859	PFAM glycosyl transferase family 9
AM447_RS01230	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM447_RS01240	COG2207	Transcriptional regulator
AM447_RS01245	COG2807	transmembrane transport
AM447_RS01250	COG0504	CTP synthase activity
AM447_RS01255	COG1683	Conserved Protein
AM447_RS01260	COG3189	MarR family transcriptional regulator
AM447_RS01265	COG3042	response to heat
AM447_RS01400	COG4695	Portal protein
AM447_RS01420	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AM447_RS01465	COG4974	Belongs to the 'phage' integrase family
AM447_RS01470	COG2199	diguanylate cyclase activity
AM447_RS01470	COG2203	Gaf domain
AM447_RS01480	COG3182	Iron-regulated membrane protein
AM447_RS01490	COG1560	Kdo2-lipid A biosynthetic process
AM447_RS01505	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AM447_RS01510	COG3706	GGDEF domain
AM447_RS01515	COG0583	DNA-binding transcription factor activity
AM447_RS01520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM447_RS01545	COG1294	oxidase, subunit
AM447_RS01550	COG1271	oxidase subunit
AM447_RS01555	COG3546	catalase activity
AM447_RS01560	COG3685	Protein conserved in bacteria
AM447_RS01565	COG3685	Protein conserved in bacteria
AM447_RS01570	COG3729	General stress protein
AM447_RS01575	COG1063	alcohol dehydrogenase
AM447_RS01580	COG3813	Protein conserved in bacteria
AM447_RS01600	COG0640	Transcriptional regulator
AM447_RS01605	COG0538	isocitrate dehydrogenase activity
AM447_RS01610	COG1187	pseudouridine synthase activity
AM447_RS01630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM447_RS01650	COG2205	protein histidine kinase activity
AM447_RS01655	COG2850	peptidyl-arginine hydroxylation
AM447_RS01675	COG1177	transmembrane transport
AM447_RS01690	COG0318	PFAM AMP-dependent synthetase and ligase
AM447_RS01695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM447_RS01700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM447_RS01705	COG0698	ribose 5-phosphate isomerase
AM447_RS01720	COG3395	kinase activity
AM447_RS01735	COG2390	Transcriptional regulator
AM447_RS01745	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM447_RS01755	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM447_RS01765	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM447_RS01775	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM447_RS01780	COG1388	LysM domain
AM447_RS01780	COG1376	ErfK ybiS ycfS ynhG family protein
AM447_RS01790	COG1309	transcriptional regulator
AM447_RS01800	COG3134	Outer membrane lipoprotein
AM447_RS01805	COG1252	NADH dehydrogenase
AM447_RS01835	COG5633	Lipoprotein
AM447_RS01840	COG0537	adenosine 5'-monophosphoramidase activity
AM447_RS01850	COG0084	hydrolase, TatD family'
AM447_RS01855	COG0470	DNA polymerase III
AM447_RS01865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM447_RS01870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM447_RS01875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM447_RS01890	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM447_RS01910	COG1399	metal-binding, possibly nucleic acid-binding protein
AM447_RS01925	COG1530	ribonuclease E activity
AM447_RS01930	COG0583	DNA-binding transcription factor activity
AM447_RS01935	COG2814	Major facilitator Superfamily
AM447_RS01955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM447_RS02005	COG1560	Kdo2-lipid A biosynthetic process
AM447_RS02025	COG5645	(Lipo)protein
AM447_RS02065	COG3381	protein complex oligomerization
AM447_RS02090	COG0583	DNA-binding transcription factor activity
AM447_RS02100	COG1335	isochorismatase
AM447_RS02115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM447_RS02120	COG1702	phosphate starvation-inducible protein PhoH
AM447_RS02140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM447_RS02150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM447_RS02165	COG1309	transcriptional regulator
AM447_RS02200	COG2233	PERMEase
AM447_RS02210	COG3729	General stress protein
AM447_RS02235	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS02245	COG0531	amino acid
AM447_RS02255	COG0174	glutamine synthetase
AM447_RS02260	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM447_RS02265	COG1396	sequence-specific DNA binding
AM447_RS02265	COG1917	Cupin 2, conserved barrel domain protein
AM447_RS02270	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS02275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM447_RS02280	COG0583	DNA-binding transcription factor activity
AM447_RS02285	COG0473	3-isopropylmalate dehydrogenase activity
AM447_RS02295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM447_RS02300	COG4638	Rieske (2fe-2S)
AM447_RS02305	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS02310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM447_RS02315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM447_RS02315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS02315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS02320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM447_RS02325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM447_RS02330	COG1882	Formate acetyltransferase
AM447_RS02335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM447_RS02340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM447_RS02350	COG2207	Transcriptional regulator
AM447_RS02355	COG3706	GGDEF domain
AM447_RS02375	COG2200	EAL domain
AM447_RS02385	COG0058	SHG alpha-glucan phosphorylase activity
AM447_RS02400	COG0670	Belongs to the BI1 family
AM447_RS02415	COG2207	Transcriptional regulator
AM447_RS02420	COG1881	PFAM PEBP family protein
AM447_RS02445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM447_RS02450	COG2274	protein secretion by the type I secretion system
AM447_RS02470	COG1832	CoA-binding protein
AM447_RS02480	COG0210	DNA helicase
AM447_RS02485	COG3304	Inner membrane component domain
AM447_RS02490	COG1289	transmembrane transporter activity
AM447_RS02495	COG3070	regulator of competence-specific genes
AM447_RS02520	COG1067	ATP-dependent peptidase activity
AM447_RS02530	COG3130	regulation of translation
AM447_RS02540	COG3009	Protein conserved in bacteria
AM447_RS02545	COG3008	intermembrane lipid transfer
AM447_RS02545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM447_RS02550	COG2995	paraquat-inducible protein a
AM447_RS02555	COG0488	(ABC) transporter
AM447_RS02565	COG0633	Ferredoxin
AM447_RS02565	COG3217	Mosc domain protein beta barrel domain protein
AM447_RS02580	COG0431	NADPH-dependent FMN reductase
AM447_RS02585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM447_RS02590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM447_RS02595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM447_RS02605	COG0308	aminopeptidase N
AM447_RS02615	COG1473	amidohydrolase
AM447_RS02625	COG0814	amino acid
AM447_RS02635	COG1522	sequence-specific DNA binding
AM447_RS02645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM447_RS02650	COG1448	Aminotransferase
AM447_RS02655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM447_RS02660	COG3108	Peptidase M15
AM447_RS02670	COG2989	Protein conserved in bacteria
AM447_RS02680	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AM447_RS02690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM447_RS02695	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM447_RS02700	COG3173	Aminoglycoside phosphotransferase
AM447_RS02715	COG3214	Protein conserved in bacteria
AM447_RS02730	COG2333	competence protein COMEC
AM447_RS02730	COG0658	competence protein
AM447_RS02740	COG0539	negative regulation of cytoplasmic translation
AM447_RS02760	COG2323	membrane
AM447_RS02765	COG1944	ATP diphosphatase activity
AM447_RS02770	COG2116	formate transmembrane transporter activity
AM447_RS02775	COG1882	Formate acetyltransferase
AM447_RS02780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM447_RS02785	COG0477	Major facilitator Superfamily
AM447_RS02795	COG3302	dmso reductase anchor subunit
AM447_RS02800	COG0437	4 iron, 4 sulfur cluster binding
AM447_RS02805	COG0243	molybdopterin cofactor binding
AM447_RS02815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM447_RS02825	COG1674	ftsk spoiiie
AM447_RS02825	COG1178	ABC-type Fe3 transport system permease component
AM447_RS02840	COG0492	ferredoxin-NADP+ reductase activity
AM447_RS02845	COG4988	ABC transporter
AM447_RS02850	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM447_RS02865	COG0542	response to heat
AM447_RS02875	COG1278	Cold shock
AM447_RS02890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM447_RS02895	COG3593	DNA synthesis involved in DNA repair
AM447_RS02905	COG2431	L-lysine efflux transmembrane transporter activity
AM447_RS02915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM447_RS02925	COG0028	Belongs to the TPP enzyme family
AM447_RS02930	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM447_RS02935	COG0702	epimerase
AM447_RS02940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM447_RS02945	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM447_RS02950	COG5001	Diguanylate cyclase
AM447_RS02950	COG2203	Gaf domain
AM447_RS02950	COG3706	GGDEF domain
AM447_RS02950	COG4251	negative regulation of phosphorylation
AM447_RS02965	COG1126	abc transporter atp-binding protein
AM447_RS02970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM447_RS02975	COG4215	(ABC) transporter
AM447_RS02980	COG4160	amino acid transport
AM447_RS02985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM447_RS02990	COG5002	protein histidine kinase activity
AM447_RS02995	COG0745	RESPONSE REGULATOR receiver
AM447_RS03010	COG1177	transmembrane transport
AM447_RS03015	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM447_RS03020	COG3842	ATPase activity
AM447_RS03025	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM447_RS03040	COG0778	Nitroreductase
AM447_RS03065	COG3226	Transcriptional regulator
AM447_RS03070	COG0738	Major facilitator superfamily
AM447_RS03075	COG0561	phosphatase activity
AM447_RS03080	COG2814	Major facilitator Superfamily
AM447_RS03090	COG0671	phosphoesterase, PA-phosphatase related
AM447_RS03095	COG1349	DNA-binding transcription factor activity
AM447_RS03100	COG1686	Belongs to the peptidase S11 family
AM447_RS03105	COG0625	glutathione transferase activity
AM447_RS03110	COG2133	pyrroloquinoline quinone binding
AM447_RS03120	COG2223	nitrite transmembrane transporter activity
AM447_RS03150	COG0747	negative chemotaxis
AM447_RS03165	COG0303	'Molybdopterin
AM447_RS03170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM447_RS03175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM447_RS03180	COG1882	Formate acetyltransferase
AM447_RS03185	COG0561	phosphatase activity
AM447_RS03195	COG1609	Transcriptional regulator
AM447_RS03200	COG2271	Major facilitator Superfamily
AM447_RS03215	COG0488	(ABC) transporter
AM447_RS03220	COG2365	Tyrosine phosphatase family
AM447_RS03225	COG1376	ErfK ybiS ycfS ynhG family protein
AM447_RS03230	COG2188	Transcriptional regulator
AM447_RS03235	COG2723	6-phospho-beta-galactosidase activity
AM447_RS03240	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM447_RS03255	COG2194	sulfuric ester hydrolase activity
AM447_RS03260	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM447_RS03275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM447_RS03280	COG0765	amino acid transport
AM447_RS03285	COG1126	abc transporter atp-binding protein
AM447_RS03290	COG0668	transmembrane transport
AM447_RS03300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM447_RS03310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM447_RS03320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM447_RS03325	COG1199	ATP-dependent helicase activity
AM447_RS03330	COG0513	Belongs to the DEAD box helicase family
AM447_RS03335	COG3958	Transketolase
AM447_RS03340	COG3959	Transketolase, thiamine diphosphate binding domain
AM447_RS03345	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS03350	COG2271	Major facilitator Superfamily
AM447_RS03355	COG0583	DNA-binding transcription factor activity
AM447_RS03360	COG1309	transcriptional regulator
AM447_RS03365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM447_RS03370	COG1131	(ABC) transporter
AM447_RS03375	COG0842	Transport permease protein
AM447_RS03380	COG0842	Transport permease protein
AM447_RS03390	COG3568	Endonuclease Exonuclease Phosphatase
AM447_RS03395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM447_RS03400	COG0392	lysyltransferase activity
AM447_RS03405	COG0670	Belongs to the BI1 family
AM447_RS03410	COG0314	molybdopterin synthase activity
AM447_RS03415	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM447_RS03425	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM447_RS03450	COG0745	RESPONSE REGULATOR receiver
AM447_RS03455	COG0642	Histidine kinase
AM447_RS03485	COG2226	methyltransferase
AM447_RS03505	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM447_RS03510	COG1881	PFAM PEBP family protein
AM447_RS03545	COG4677	pectinesterase activity
AM447_RS03555	COG0589	response to stress
AM447_RS03560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM447_RS03590	COG0789	Transcriptional regulator
AM447_RS03595	COG2200	EAL domain
AM447_RS03620	COG0561	phosphatase activity
AM447_RS03630	COG4149	molybdate abc transporter
AM447_RS03635	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM447_RS03645	COG2005	Transcriptional regulator
AM447_RS03645	COG3585	molybdate ion transport
AM447_RS03650	COG1119	ATPase activity
AM447_RS03660	COG1085	galactose-1-phosphate uridylyltransferase
AM447_RS03670	COG2017	converts alpha-aldose to the beta-anomer
AM447_RS03680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM447_RS03695	COG3201	nicotinamide mononucleotide transporter
AM447_RS03700	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM447_RS03740	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM447_RS03745	COG2885	chlorophyll binding
AM447_RS03755	COG3064	Membrane
AM447_RS03760	COG0848	biopolymer transport protein
AM447_RS03765	COG0811	peptide transport
AM447_RS03770	COG0824	Thioesterase
AM447_RS03775	COG3790	cyd operon protein YbgE
AM447_RS03780	COG4890	Cyd operon protein YbgT
AM447_RS03785	COG1294	oxidase, subunit
AM447_RS03790	COG1271	oxidase subunit
AM447_RS03800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM447_RS03810	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM447_RS03815	COG0567	Dehydrogenase, E1 component
AM447_RS03820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM447_RS03825	COG1053	succinate dehydrogenase
AM447_RS03830	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM447_RS03835	COG2009	succinate dehydrogenase
AM447_RS03875	COG1984	allophanate hydrolase subunit 2
AM447_RS03880	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM447_RS03895	COG0415	Belongs to the DNA photolyase family
AM447_RS03925	COG2205	protein histidine kinase activity
AM447_RS03930	COG0745	RESPONSE REGULATOR receiver
AM447_RS03940	COG0033	Phosphoglucomutase
AM447_RS03950	COG0596	Alpha beta hydrolase
AM447_RS03965	COG0735	belongs to the Fur family
AM447_RS04010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM447_RS04015	COG1846	Transcriptional regulator
AM447_RS04015	COG1940	carbohydrate kinase activity
AM447_RS04020	COG0647	UMP catabolic process
AM447_RS04025	COG0367	asparagine synthase
AM447_RS04070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM447_RS04080	COG1702	phosphate starvation-inducible protein PhoH
AM447_RS04105	COG0765	amino acid transport
AM447_RS04110	COG0765	amino acid transport
AM447_RS04115	COG1126	abc transporter atp-binding protein
AM447_RS04130	COG2888	peptidyl-tyrosine sulfation
AM447_RS04145	COG1466	dna polymerase III delta subunit
AM447_RS04165	COG0799	negative regulation of ribosome biogenesis
AM447_RS04175	COG0768	penicillin binding
AM447_RS04180	COG0772	Belongs to the SEDS family
AM447_RS04185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM447_RS04190	COG1686	Belongs to the peptidase S11 family
AM447_RS04205	COG0583	DNA-binding transcription factor activity
AM447_RS04215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM447_RS04220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM447_RS04240	COG3069	C4-dicarboxylate transmembrane transporter activity
AM447_RS04245	COG3719	Belongs to the RNase T2 family
AM447_RS04250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM447_RS04270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM447_RS04275	COG0583	DNA-binding transcription factor activity
AM447_RS04280	COG3969	phosphoadenosine phosphosulfate
AM447_RS04285	COG1475	DNA binding
AM447_RS04290	COG0436	Aminotransferase
AM447_RS04315	COG1129	ABC transporter
AM447_RS04320	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS04325	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS04335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM447_RS04350	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM447_RS04360	COG0402	S-adenosylhomocysteine deaminase activity
AM447_RS04370	COG0483	inositol monophosphate 1-phosphatase activity
AM447_RS04375	COG2271	Major facilitator Superfamily
AM447_RS04405	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS04410	COG1129	ABC transporter
AM447_RS04415	COG0371	Dehydrogenase
AM447_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS04435	COG2879	small protein
AM447_RS04440	COG1966	Carbon starvation protein
AM447_RS04450	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS04455	COG3433	isochorismatase activity
AM447_RS04455	COG1535	isochorismatase
AM447_RS04460	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM447_RS04465	COG1169	isochorismate synthase
AM447_RS04470	COG4592	Periplasmic binding protein
AM447_RS04480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM447_RS04485	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM447_RS04490	COG1120	ATPase activity
AM447_RS04495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM447_RS04495	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM447_RS04500	COG3251	PFAM MbtH domain protein
AM447_RS04505	COG2382	esterase
AM447_RS04515	COG4771	TonB-dependent receptor
AM447_RS04525	COG1879	ABC-type sugar transport system periplasmic component
AM447_RS04535	COG1129	ABC transporter
AM447_RS04540	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS04545	COG5464	transposase or invertase
AM447_RS04550	COG2390	Transcriptional regulator
AM447_RS04555	COG3959	Transketolase, thiamine diphosphate binding domain
AM447_RS04560	COG3958	Transketolase
AM447_RS04570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM447_RS04580	COG0583	DNA-binding transcription factor activity
AM447_RS04585	COG0668	transmembrane transport
AM447_RS04595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM447_RS04625	COG0747	negative chemotaxis
AM447_RS04630	COG0601	transmembrane transport
AM447_RS04635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM447_RS04640	COG0444	Belongs to the ABC transporter superfamily
AM447_RS04645	COG4608	Belongs to the ABC transporter superfamily
AM447_RS04660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM447_RS04665	COG4221	oxidoreductase activity
AM447_RS04675	COG4215	(ABC) transporter
AM447_RS04680	COG0765	amino acid transport
AM447_RS04685	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM447_RS04700	COG0697	spore germination
AM447_RS04715	COG4608	Belongs to the ABC transporter superfamily
AM447_RS04720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM447_RS04730	COG4166	transmembrane transport
AM447_RS04740	COG3698	Phosphodiester glycosidase
AM447_RS04785	COG2315	Protein conserved in bacteria
AM447_RS04790	COG0778	Nitroreductase
AM447_RS04820	COG0477	Major facilitator Superfamily
AM447_RS04825	COG0668	transmembrane transport
AM447_RS04830	COG1609	Transcriptional regulator
AM447_RS04840	COG0673	inositol 2-dehydrogenase activity
AM447_RS04850	COG2211	Major facilitator Superfamily
AM447_RS04855	COG1113	amino acid transport
AM447_RS04870	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS04875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM447_RS04890	COG0531	amino acid
AM447_RS04905	COG4680	protein conserved in bacteria
AM447_RS04950	COG0667	Aldo Keto reductase
AM447_RS04955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM447_RS04960	COG1473	amidohydrolase
AM447_RS04985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM447_RS04990	COG1120	ATPase activity
AM447_RS04995	COG1566	PFAM secretion protein HlyD family protein
AM447_RS05040	COG4211	Belongs to the binding-protein-dependent transport system permease family
AM447_RS05045	COG1129	ABC transporter
AM447_RS05060	COG0673	inositol 2-dehydrogenase activity
AM447_RS05090	COG3104	oligopeptide transport
AM447_RS05095	COG1982	Orn Lys Arg decarboxylase major
AM447_RS05100	COG0531	amino acid
AM447_RS05110	COG3710	Transcriptional regulator
AM447_RS05120	COG1560	Kdo2-lipid A biosynthetic process
AM447_RS05165	COG2501	S4 domain
AM447_RS05175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM447_RS05195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM447_RS05200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM447_RS05215	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM447_RS05220	COG4181	ATPase activity
AM447_RS05225	COG2755	lipolytic protein G-D-S-L family
AM447_RS05230	COG0300	oxidoreductase activity
AM447_RS05235	COG3118	belongs to the thioredoxin family
AM447_RS05245	COG0390	transport system, permease component
AM447_RS05250	COG4619	ABC transporter
AM447_RS05255	COG0330	HflC and HflK could
AM447_RS05260	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM447_RS05275	COG3735	TraB family
AM447_RS05280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM447_RS05290	COG2223	nitrite transmembrane transporter activity
AM447_RS05295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM447_RS05295	COG4651	solute:proton antiporter activity
AM447_RS05300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM447_RS05340	COG2832	Protein of unknown function (DUF454)
AM447_RS05345	COG3923	Primosomal replication protein n
AM447_RS05355	COG5464	transposase or invertase
AM447_RS05360	COG3264	Mechanosensitive ion channel
AM447_RS05360	COG1196	nuclear chromosome segregation
AM447_RS05365	COG1309	transcriptional regulator
AM447_RS05370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM447_RS05375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM447_RS05390	COG0110	maltose O-acetyltransferase activity
AM447_RS05435	COG1874	Beta-galactosidase
AM447_RS05440	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AM447_RS05445	COG3833	ABC-type maltose transport systems, permease component
AM447_RS05450	COG1175	transmembrane transport
AM447_RS05455	COG2182	Extracellular solute-binding protein
AM447_RS05465	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM447_RS05480	COG2364	Membrane
AM447_RS05510	COG3695	enzyme binding
AM447_RS05515	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AM447_RS05520	COG1946	Acyl-CoA thioesterase
AM447_RS05525	COG0004	ammonium transporteR
AM447_RS05530	COG0347	Belongs to the P(II) protein family
AM447_RS05535	COG1132	(ABC) transporter
AM447_RS05540	COG1132	(ABC) transporter
AM447_RS05545	COG1522	sequence-specific DNA binding
AM447_RS05560	COG4533	DNA binding
AM447_RS05570	COG0824	Thioesterase
AM447_RS05575	COG1555	photosystem II stabilization
AM447_RS05580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM447_RS05585	COG0776	regulation of translation
AM447_RS05590	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM447_RS05610	COG0271	Belongs to the BolA IbaG family
AM447_RS05615	COG3056	Lipoprotein
AM447_RS05620	COG2223	nitrite transmembrane transporter activity
AM447_RS05625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM447_RS05630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM447_RS05635	COG1845	cytochrome c oxidase, subunit III
AM447_RS05640	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM447_RS05655	COG1414	Transcriptional regulator
AM447_RS05660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM447_RS05665	COG1053	succinate dehydrogenase
AM447_RS05675	COG1053	succinate dehydrogenase
AM447_RS05690	COG0673	inositol 2-dehydrogenase activity
AM447_RS05695	COG2814	Major facilitator Superfamily
AM447_RS05705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM447_RS05710	COG0693	protein deglycase activity
AM447_RS05730	COG0142	geranyltranstransferase activity
AM447_RS05740	COG0667	Aldo Keto reductase
AM447_RS05745	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM447_RS05765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM447_RS05765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM447_RS05775	COG4238	major outer membrane lipoprotein
AM447_RS05795	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM447_RS05800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM447_RS05805	COG1862	Preprotein translocase
AM447_RS05825	COG0450	alkyl hydroperoxide reductase
AM447_RS05830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS05845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM447_RS05855	COG1228	amidohydrolase
AM447_RS05865	COG1335	isochorismatase
AM447_RS05870	COG0583	DNA-binding transcription factor activity
AM447_RS05875	COG0366	Alpha amylase catalytic
AM447_RS05900	COG0420	3'-5' exonuclease activity
AM447_RS05905	COG0419	ATPase involved in DNA repair
AM447_RS05910	COG1940	carbohydrate kinase activity
AM447_RS05925	COG4126	flavin adenine dinucleotide binding
AM447_RS05935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM447_RS05940	COG3416	Protein conserved in bacteria
AM447_RS05950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM447_RS05960	COG1785	Belongs to the alkaline phosphatase family
AM447_RS06000	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM447_RS06005	COG1335	isochorismatase
AM447_RS06010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM447_RS06015	COG0113	porphobilinogen synthase activity
AM447_RS06020	COG1943	Transposase
AM447_RS06030	COG2175	clavaminate synthase activity
AM447_RS06035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM447_RS06040	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AM447_RS06045	COG4521	taurine ABC transporter
AM447_RS06050	COG2040	homocysteine
AM447_RS06055	COG0833	amino acid
AM447_RS06065	COG4303	Ethanolamine ammonia lyase large subunit
AM447_RS06070	COG4302	ethanolamine ammonia-lyase activity
AM447_RS06105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM447_RS06110	COG1126	abc transporter atp-binding protein
AM447_RS06115	COG4597	amino acid ABC transporter
AM447_RS06120	COG0765	amino acid transport
AM447_RS06135	COG3188	usher protein
AM447_RS06160	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM447_RS06170	COG3639	organic phosphonate transmembrane transporter activity
AM447_RS06200	COG0791	NLP P60 protein
AM447_RS06225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM447_RS06250	COG2963	transposase activity
AM447_RS06260	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM447_RS06265	COG0022	dehydrogenase e1 component
AM447_RS06270	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM447_RS06275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM447_RS06300	COG1070	Carbohydrate kinase
AM447_RS06305	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS06310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM447_RS06315	COG3775	system Galactitol-specific IIC component
AM447_RS06320	COG0625	glutathione transferase activity
AM447_RS06325	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AM447_RS06345	COG0579	oxidoreductase
AM447_RS06350	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS06355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM447_RS06360	COG1113	amino acid transport
AM447_RS06365	COG1802	Transcriptional regulator
AM447_RS06385	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM447_RS06390	COG0454	-acetyltransferase
AM447_RS06405	COG2991	Protein conserved in bacteria
AM447_RS06420	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM447_RS06425	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM447_RS06445	COG3034	peptidoglycan biosynthetic process
AM447_RS06450	COG0121	glutamine amidotransferase
AM447_RS06460	COG1960	acyl-CoA dehydrogenase activity
AM447_RS06465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM447_RS06475	COG0583	DNA-binding transcription factor activity
AM447_RS06490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM447_RS06500	COG2226	methyltransferase
AM447_RS06510	COG1388	LysM domain
AM447_RS06510	COG0741	lytic transglycosylase activity
AM447_RS06515	COG2226	methyltransferase
AM447_RS06530	COG0583	DNA-binding transcription factor activity
AM447_RS06535	COG0656	L-ascorbic acid biosynthetic process
AM447_RS06570	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM447_RS06580	COG2011	ABC-type metal ion transport system permease component
AM447_RS06585	COG1464	Belongs to the NlpA lipoprotein family
AM447_RS06595	COG1720	tRNA m6t6A37 methyltransferase activity
AM447_RS06605	COG0791	NLP P60 protein
AM447_RS06610	COG3015	lipoprotein NlpE involved in copper resistance
AM447_RS06615	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM447_RS06630	COG4568	rho-dependent transcription termination
AM447_RS06640	COG0346	lactoylglutathione lyase activity
AM447_RS06645	COG1982	Orn Lys Arg decarboxylase major
AM447_RS06655	COG0587	DNA-directed DNA polymerase activity
AM447_RS06685	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AM447_RS06695	COG0750	zinc metalloprotease
AM447_RS06700	COG0575	Belongs to the CDS family
AM447_RS06715	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM447_RS06740	COG0024	Methionine aminopeptidase
AM447_RS06745	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AM447_RS06760	COG3835	regulator
AM447_RS06765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM447_RS06785	COG2860	membrane
AM447_RS06805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM447_RS06810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM447_RS06815	COG1120	ATPase activity
AM447_RS06820	COG4774	siderophore transport
AM447_RS06825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM447_RS06915	COG1643	Atp-dependent helicase
AM447_RS06920	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM447_RS06940	COG0617	tRNA 3'-terminal CCA addition
AM447_RS06945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM447_RS06965	COG0726	polysaccharide deacetylase
AM447_RS06970	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS06975	COG0842	Transport permease protein
AM447_RS06980	COG1131	(ABC) transporter
AM447_RS06985	COG0288	reversible hydration of carbon dioxide
AM447_RS06995	COG4993	Dehydrogenase
AM447_RS07000	COG2132	Multicopper oxidase
AM447_RS07040	COG3064	Membrane
AM447_RS07055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM447_RS07060	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM447_RS07065	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM447_RS07070	COG2186	Transcriptional regulator
AM447_RS07075	COG1113	amino acid transport
AM447_RS07080	COG2211	Major facilitator Superfamily
AM447_RS07085	COG3940	Belongs to the glycosyl hydrolase 43 family
AM447_RS07090	COG3725	Membrane protein required for beta-lactamase induction
AM447_RS07095	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM447_RS07105	COG4969	Belongs to the N-Me-Phe pilin family
AM447_RS07110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM447_RS07115	COG1459	type II secretion system
AM447_RS07140	COG0494	nUDIX hydrolase
AM447_RS07160	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM447_RS07165	COG0849	cell division
AM447_RS07190	COG0772	Belongs to the SEDS family
AM447_RS07205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM447_RS07210	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM447_RS07215	COG0768	penicillin binding
AM447_RS07240	COG1609	Transcriptional regulator
AM447_RS07250	COG0028	Belongs to the TPP enzyme family
AM447_RS07300	COG0738	Major facilitator superfamily
AM447_RS07310	COG0583	DNA-binding transcription factor activity
AM447_RS07315	COG2271	Major facilitator Superfamily
AM447_RS07320	COG2814	Major facilitator Superfamily
AM447_RS07340	COG1178	ABC-type Fe3 transport system permease component
AM447_RS07350	COG0586	Pfam SNARE associated Golgi protein
AM447_RS07370	COG0235	Class ii aldolase
AM447_RS07375	COG0417	DNA replication proofreading
AM447_RS07385	COG0564	pseudouridine synthase activity
AM447_RS07400	COG3493	citrate carrier protein
AM447_RS07415	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM447_RS07420	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM447_RS07430	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM447_RS07485	COG0505	Belongs to the CarA family
AM447_RS07495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM447_RS07505	COG3152	Membrane
AM447_RS07520	COG1047	Peptidyl-prolyl cis-trans
AM447_RS07535	COG0196	riboflavin kinase activity
AM447_RS07550	COG0583	DNA-binding transcription factor activity
AM447_RS07575	COG4735	regulation of single-species biofilm formation
AM447_RS07580	COG1584	GPR1 FUN34 yaaH family protein
AM447_RS07585	COG0477	Major facilitator Superfamily
AM447_RS07590	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM447_RS07595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM447_RS07600	COG1115	amino acid carrier protein
AM447_RS07615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM447_RS07625	COG0460	homoserine dehydrogenase
AM447_RS07625	COG0527	aspartate kinase activity
AM447_RS07635	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM447_RS07645	COG0745	RESPONSE REGULATOR receiver
AM447_RS07650	COG4452	Inner membrane protein CreD
AM447_RS07655	COG2205	protein histidine kinase activity
AM447_RS07660	COG0745	RESPONSE REGULATOR receiver
AM447_RS07665	COG3045	CreA protein
AM447_RS07670	COG3708	Transcriptional regulator
AM447_RS07670	COG2207	Transcriptional regulator
AM447_RS07690	COG0741	lytic transglycosylase activity
AM447_RS07700	COG0488	(ABC) transporter
AM447_RS07710	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AM447_RS07715	COG0560	Phosphoserine phosphatase
AM447_RS07725	COG3726	membrane protein affecting hemolysin expression
AM447_RS07755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM447_RS07760	COG0084	hydrolase, TatD family'
AM447_RS07765	COG4667	esterase of the alpha-beta hydrolase superfamily
AM447_RS07770	COG5487	UPF0391 membrane protein
AM447_RS07775	COG2823	Periplasmic or secreted lipoprotein
AM447_RS07785	COG1011	Hydrolase
AM447_RS07790	COG0456	acetyltransferase
AM447_RS07795	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AM447_RS07825	COG3706	GGDEF domain
AM447_RS07830	COG4114	ferric iron reductase
AM447_RS07835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS07835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS07840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM447_RS07845	COG2197	response regulator
AM447_RS07850	COG2197	response regulator
AM447_RS07865	COG2966	Psort location CytoplasmicMembrane, score
AM447_RS07880	COG1484	DNA-dependent DNA replication
AM447_RS07895	COG5464	transposase or invertase
AM447_RS07905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM447_RS07910	COG3716	PTS system mannose fructose sorbose family IID component
AM447_RS07915	COG3715	PTS system
AM447_RS07930	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM447_RS07930	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AM447_RS07935	COG0456	acetyltransferase
AM447_RS07935	COG1214	PFAM Peptidase M22, glycoprotease
AM447_RS07945	COG1737	Transcriptional regulator
AM447_RS07950	COG0800	Aldolase
AM447_RS07955	COG3734	2-keto-3-deoxy-galactonokinase
AM447_RS07970	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AM447_RS08005	COG1846	Transcriptional regulator
AM447_RS08010	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM447_RS08020	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS08025	COG3384	dioxygenase
AM447_RS08035	COG3971	2-oxopent-4-enoate hydratase activity
AM447_RS08055	COG2368	4-hydroxyphenylacetate
AM447_RS08060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM447_RS08075	COG1966	Carbon starvation protein
AM447_RS08080	COG2879	small protein
AM447_RS08085	COG0523	cobalamin synthesis protein
AM447_RS08095	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS08100	COG5464	transposase or invertase
AM447_RS08105	COG1917	Cupin 2, conserved barrel domain protein
AM447_RS08105	COG2207	Transcriptional regulator
AM447_RS08115	COG2733	membrane
AM447_RS08130	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AM447_RS08135	COG1924	4 iron, 4 sulfur cluster binding
AM447_RS08150	COG1566	PFAM secretion protein HlyD family protein
AM447_RS08160	COG5457	Domain of unknown function (DUF1127)
AM447_RS08165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM447_RS08175	COG0583	DNA-binding transcription factor activity
AM447_RS08180	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM447_RS08190	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS08195	COG1129	ABC transporter
AM447_RS08200	COG1879	ABC-type sugar transport system periplasmic component
AM447_RS08210	COG3706	GGDEF domain
AM447_RS08215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM447_RS08220	COG1129	ABC transporter
AM447_RS08220	COG0842	Transport permease protein
AM447_RS08225	COG0842	Transport permease protein
AM447_RS08255	COG2850	peptidyl-arginine hydroxylation
AM447_RS08270	COG5002	protein histidine kinase activity
AM447_RS08275	COG0745	RESPONSE REGULATOR receiver
AM447_RS08285	COG1538	Outer membrane efflux protein
AM447_RS08290	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM447_RS08295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM447_RS08300	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM447_RS08310	COG3040	lipid binding
AM447_RS08315	COG0789	Transcriptional regulator
AM447_RS08320	COG3631	Ketosteroid isomerase-related protein
AM447_RS08325	COG0300	oxidoreductase activity
AM447_RS08340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM447_RS08360	COG3272	Protein of unknown function (DUF1722)
AM447_RS08365	COG4580	involved in the transport of maltose and maltodextrins
AM447_RS08370	COG2115	Belongs to the xylose isomerase family
AM447_RS08375	COG2211	Major facilitator Superfamily
AM447_RS08380	COG3507	Belongs to the glycosyl hydrolase 43 family
AM447_RS08400	COG1216	Glycosyl transferase, family 2
AM447_RS08445	COG2801	Transposase and inactivated derivatives
AM447_RS08450	COG2801	Transposase and inactivated derivatives
AM447_RS08460	COG1715	Restriction endonuclease
AM447_RS08465	COG1196	nuclear chromosome segregation
AM447_RS08485	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AM447_RS08490	COG0582	viral genome integration into host DNA
AM447_RS08505	COG0288	reversible hydration of carbon dioxide
AM447_RS08510	COG0659	secondary active sulfate transmembrane transporter activity
AM447_RS08515	COG1064	alcohol dehydrogenase
AM447_RS08520	COG1175	transmembrane transport
AM447_RS08525	COG0395	ABC-type sugar transport system, permease component
AM447_RS08530	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM447_RS08535	COG3842	ATPase activity
AM447_RS08550	COG1082	Xylose isomerase domain protein TIM barrel
AM447_RS08560	COG3962	Belongs to the TPP enzyme family
AM447_RS08565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM447_RS08570	COG1737	Transcriptional regulator
AM447_RS08570	COG0837	glucose binding
AM447_RS08585	COG3718	enzyme involved in inositol metabolism
AM447_RS08600	COG0433	COG0433 Predicted ATPase
AM447_RS08605	COG0795	lipopolysaccharide-transporting ATPase activity
AM447_RS08610	COG0795	lipopolysaccharide-transporting ATPase activity
AM447_RS08625	COG2927	DNA polymerase III (CHI subunit)
AM447_RS08630	COG0525	valine-tRNA ligase activity
AM447_RS08655	COG2731	YhcH YjgK YiaL family protein
AM447_RS08695	COG1263	PTS System
AM447_RS08695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM447_RS08700	COG0366	Alpha amylase catalytic
AM447_RS08705	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS08710	COG1486	melibiose metabolic process
AM447_RS08730	COG0602	queuosine metabolic process
AM447_RS08735	COG2026	Addiction module toxin, RelE StbE family
AM447_RS08740	COG3077	Addiction module antitoxin, RelB DinJ family
AM447_RS08745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS08745	COG3711	transcriptional antiterminator
AM447_RS08750	COG2706	6-phosphogluconolactonase activity
AM447_RS08765	COG3964	amidohydrolase
AM447_RS08800	COG0312	modulator of DNA gyrase
AM447_RS08820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM447_RS08830	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS08835	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS08840	COG1129	ABC transporter
AM447_RS08845	COG1879	ABC-type sugar transport system periplasmic component
AM447_RS08860	COG2105	PFAM AIG2 family protein
AM447_RS08865	COG2911	Protein conserved in bacteria
AM447_RS08870	COG0729	surface antigen
AM447_RS08880	COG1253	flavin adenine dinucleotide binding
AM447_RS08905	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM447_RS08920	COG1733	regulation of RNA biosynthetic process
AM447_RS08925	COG0702	epimerase
AM447_RS08935	COG0697	spore germination
AM447_RS08945	COG1113	amino acid transport
AM447_RS08950	COG0545	Peptidyl-prolyl cis-trans isomerase
AM447_RS08955	COG3061	Opacity-associated protein A
AM447_RS08965	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM447_RS08970	COG2965	DNA replication, synthesis of RNA primer
AM447_RS09030	COG1073	alpha beta
AM447_RS09035	COG3650	response to hydrogen peroxide
AM447_RS09045	COG1960	acyl-CoA dehydrogenase activity
AM447_RS09050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM447_RS09055	COG0557	exoribonuclease II activity
AM447_RS09070	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AM447_RS09080	COG0330	HflC and HflK could
AM447_RS09085	COG0330	HflC and HflK could
AM447_RS09090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM447_RS09110	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM447_RS09115	COG0802	atpase or kinase
AM447_RS09120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM447_RS09120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM447_RS09125	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM447_RS09150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM447_RS09170	COG1511	domain protein
AM447_RS09170	COG3264	Mechanosensitive ion channel
AM447_RS09185	COG1053	succinate dehydrogenase
AM447_RS09190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM447_RS09210	COG2076	Multidrug Resistance protein
AM447_RS09215	COG5510	response to toxic substance
AM447_RS09230	COG1509	lysine 2,3-aminomutase activity
AM447_RS09295	COG0531	amino acid
AM447_RS09300	COG3030	protein affecting phage T7 exclusion by the F plasmid
AM447_RS09310	COG1027	Aspartate ammonia-lyase
AM447_RS09315	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM447_RS09330	COG1309	transcriptional regulator
AM447_RS09360	COG0457	Tetratricopeptide repeat
AM447_RS09365	COG0726	polysaccharide deacetylase
AM447_RS09365	COG1649	PFAM Uncharacterised BCR, COG1649
AM447_RS09370	COG1215	transferase activity, transferring glycosyl groups
AM447_RS09390	COG0861	Integral membrane protein TerC family
AM447_RS09420	COG1486	melibiose metabolic process
AM447_RS09430	COG2169	Transcriptional regulator
AM447_RS09445	COG2824	Alkylphosphonate utilization operon protein PhnA
AM447_RS09450	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AM447_RS09455	COG2188	Transcriptional regulator
AM447_RS09460	COG3624	Phosphonate C-P lyase system protein PhnG
AM447_RS09465	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM447_RS09470	COG3626	phosphonate metabolism
AM447_RS09475	COG3627	carbon phosphorus lyase activity
AM447_RS09480	COG4107	phosphonate C-P lyase system protein PhnK
AM447_RS09485	COG4778	phosphonate C-P lyase system protein PhnL
AM447_RS09490	COG3454	Phosphonate metabolism
AM447_RS09500	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM447_RS09510	COG4191	Histidine kinase
AM447_RS09510	COG0784	Response regulator, receiver
AM447_RS09515	COG1129	ABC transporter
AM447_RS09520	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS09555	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM447_RS09560	COG1301	dicarboxylic acid transport
AM447_RS09570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM447_RS09580	COG3162	membrane
AM447_RS09610	COG3539	Fimbrial protein
AM447_RS09615	COG1346	cytolysis
AM447_RS09620	COG1380	Effector of murein hydrolase LrgA
AM447_RS09625	COG0583	DNA-binding transcription factor activity
AM447_RS09630	COG0025	NhaP-type Na H and K H
AM447_RS09635	COG2252	PERMEase
AM447_RS09645	COG0625	glutathione transferase activity
AM447_RS09650	COG0789	Transcriptional regulator
AM447_RS09660	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM447_RS09695	COG1234	tRNA 3'-trailer cleavage
AM447_RS09700	COG1609	Transcriptional regulator
AM447_RS09705	COG0483	inositol monophosphate 1-phosphatase activity
AM447_RS09720	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM447_RS09740	COG4771	TonB-dependent receptor
AM447_RS09745	COG0741	lytic transglycosylase activity
AM447_RS09760	COG2315	Protein conserved in bacteria
AM447_RS09765	COG0432	Pfam Uncharacterised protein family UPF0047
AM447_RS09780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM447_RS09785	COG0305	Participates in initiation and elongation during chromosome replication
AM447_RS09800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM447_RS09810	COG0735	belongs to the Fur family
AM447_RS09815	COG3237	CsbD-like
AM447_RS09820	COG0534	Mate efflux family protein
AM447_RS09830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM447_RS09905	COG0251	oxidation-reduction process
AM447_RS09915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM447_RS09930	COG0527	aspartate kinase activity
AM447_RS09980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM447_RS09990	COG0456	acetyltransferase
AM447_RS10030	COG0151	Belongs to the GarS family
AM447_RS10040	COG4191	Histidine kinase
AM447_RS10045	COG3678	ATP-independent chaperone mediated protein folding
AM447_RS10080	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AM447_RS10095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM447_RS10100	COG2104	thiamine diphosphate biosynthetic process
AM447_RS10120	COG3706	GGDEF domain
AM447_RS10130	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM447_RS10135	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM447_RS10175	COG0250	Participates in transcription elongation, termination and antitermination
AM447_RS10225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM447_RS10255	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AM447_RS10265	COG1739	Uncharacterized protein family UPF0029
AM447_RS10310	COG0805	protein transport
AM447_RS10330	COG3165	ubiquinone biosynthetic process from chorismate
AM447_RS10360	COG0583	DNA-binding transcription factor activity
AM447_RS10365	COG0697	spore germination
AM447_RS10370	COG0561	phosphatase activity
AM447_RS10375	COG2267	carboxylic ester hydrolase activity
AM447_RS10380	COG1280	lysine exporter protein (LysE YggA)
AM447_RS10390	COG1280	lysine exporter protein (LysE YggA)
AM447_RS10425	COG0210	DNA helicase
AM447_RS10430	COG1011	Hydrolase
AM447_RS10460	COG3072	Adenylate cyclase
AM447_RS10475	COG2959	enzyme of heme biosynthesis
AM447_RS10480	COG3071	HemY protein
AM447_RS10525	COG2244	polysaccharide biosynthetic process
AM447_RS10530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM447_RS10535	COG0456	acetyltransferase
AM447_RS10540	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM447_RS10545	COG1088	dTDP-glucose 4,6-dehydratase activity
AM447_RS10550	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM447_RS10555	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM447_RS10565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM447_RS10570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM447_RS10580	COG3118	belongs to the thioredoxin family
AM447_RS10610	COG1811	Na channel or pump
AM447_RS10620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM447_RS10625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM447_RS10635	COG0583	DNA-binding transcription factor activity
AM447_RS10640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM447_RS10655	COG3978	acetolactate synthase activity
AM447_RS10675	COG3085	chromosome segregation
AM447_RS10750	COG0583	DNA-binding transcription factor activity
AM447_RS10775	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM447_RS10790	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM447_RS10795	COG2207	Transcriptional regulator
AM447_RS10805	COG0371	Dehydrogenase
AM447_RS10810	COG0697	spore germination
AM447_RS10820	COG0583	DNA-binding transcription factor activity
AM447_RS10830	COG0737	Belongs to the 5'-nucleotidase family
AM447_RS10840	COG0527	aspartate kinase activity
AM447_RS10840	COG0460	homoserine dehydrogenase
AM447_RS10845	COG0626	cystathionine gamma-synthase activity
AM447_RS10860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM447_RS10865	COG1609	Transcriptional regulator
AM447_RS10870	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM447_RS10885	COG1575	Belongs to the MenA family. Type 1 subfamily
AM447_RS10905	COG3678	ATP-independent chaperone mediated protein folding
AM447_RS10910	COG0745	RESPONSE REGULATOR receiver
AM447_RS10915	COG2205	protein histidine kinase activity
AM447_RS10920	COG2258	MOSC domain
AM447_RS10925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM447_RS10970	COG1129	ABC transporter
AM447_RS10975	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS10980	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS10985	COG1454	alcohol dehydrogenase
AM447_RS10995	COG2211	Major facilitator Superfamily
AM447_RS11040	COG3383	formate dehydrogenase (NAD+) activity
AM447_RS11040	COG0243	molybdopterin cofactor binding
AM447_RS11045	COG3383	formate dehydrogenase (NAD+) activity
AM447_RS11045	COG0243	molybdopterin cofactor binding
AM447_RS11050	COG0437	4 iron, 4 sulfur cluster binding
AM447_RS11055	COG2864	formate dehydrogenase
AM447_RS11070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM447_RS11080	COG0456	acetyltransferase
AM447_RS11095	COG1011	Hydrolase
AM447_RS11115	COG3852	Histidine kinase
AM447_RS11125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM447_RS11150	COG0204	Acyl-transferase
AM447_RS11160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM447_RS11165	COG3084	Protein conserved in bacteria
AM447_RS11175	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM447_RS11205	COG2186	Transcriptional regulator
AM447_RS11210	COG0477	Major facilitator Superfamily
AM447_RS11215	COG1609	Transcriptional regulator
AM447_RS11220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM447_RS11230	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS11235	COG1129	ABC transporter
AM447_RS11265	COG1522	sequence-specific DNA binding
AM447_RS11270	COG0716	FMN binding
AM447_RS11290	COG3312	ion transport
AM447_RS11340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM447_RS11430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM447_RS11435	COG0573	inorganic phosphate transmembrane transporter activity
AM447_RS11440	COG0581	inorganic phosphate transmembrane transporter activity
AM447_RS11445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM447_RS11450	COG0704	Plays a role in the regulation of phosphate uptake
AM447_RS11460	COG2382	esterase
AM447_RS11465	COG0363	glucosamine-6-phosphate deaminase activity
AM447_RS11470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM447_RS11480	COG2252	PERMEase
AM447_RS11485	COG0431	NADPH-dependent FMN reductase
AM447_RS11490	COG2091	lysine biosynthetic process via aminoadipic acid
AM447_RS11520	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM447_RS11555	COG0187	DNA topoisomerase II activity
AM447_RS11560	COG0561	phosphatase activity
AM447_RS11575	COG2186	Transcriptional regulator
AM447_RS11580	COG3734	2-keto-3-deoxy-galactonokinase
AM447_RS11585	COG0800	Aldolase
AM447_RS11595	COG2271	Major facilitator Superfamily
AM447_RS11600	COG0823	Involved in the tonB-independent uptake of proteins
AM447_RS11605	COG5645	(Lipo)protein
AM447_RS11620	COG3645	SOS response
AM447_RS11630	COG2188	Transcriptional regulator
AM447_RS11645	COG2149	membrane
AM447_RS11665	COG2610	gluconate transmembrane transporter activity
AM447_RS11670	COG0583	DNA-binding transcription factor activity
AM447_RS11675	COG2814	Major facilitator Superfamily
AM447_RS11700	COG0028	Belongs to the TPP enzyme family
AM447_RS11705	COG0440	acetolactate synthase activity
AM447_RS11710	COG2197	response regulator
AM447_RS11720	COG2271	Major facilitator Superfamily
AM447_RS11765	COG2188	Transcriptional regulator
AM447_RS11790	COG4580	involved in the transport of maltose and maltodextrins
AM447_RS11795	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM447_RS11800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS11800	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS11810	COG1609	Transcriptional regulator
AM447_RS11820	COG3384	dioxygenase
AM447_RS11825	COG3384	dioxygenase
AM447_RS11830	COG0583	DNA-binding transcription factor activity
AM447_RS11835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AM447_RS11840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM447_RS11845	COG2828	Protein conserved in bacteria
AM447_RS11860	COG0697	spore germination
AM447_RS11865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM447_RS11865	COG1263	PTS System
AM447_RS11875	COG2814	Major facilitator Superfamily
AM447_RS11885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM447_RS11920	COG0583	DNA-binding transcription factor activity
AM447_RS11945	COG1464	Belongs to the NlpA lipoprotein family
AM447_RS11960	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AM447_RS11970	COG1064	alcohol dehydrogenase
AM447_RS12000	COG2211	Major facilitator Superfamily
AM447_RS12005	COG1501	Belongs to the glycosyl hydrolase 31 family
AM447_RS12015	COG1486	melibiose metabolic process
AM447_RS12020	COG1263	PTS System
AM447_RS12020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM447_RS12025	COG2982	Protein involved in outer membrane biogenesis
AM447_RS12030	COG2233	PERMEase
AM447_RS12035	COG0786	glutamate:sodium symporter activity
AM447_RS12050	COG3074	FtsZ-dependent cytokinesis
AM447_RS12055	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM447_RS12080	COG3152	Membrane
AM447_RS12090	COG1494	fructose-1,6-bisphosphatase
AM447_RS12095	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM447_RS12100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM447_RS12105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM447_RS12125	COG2860	membrane
AM447_RS12135	COG2169	Transcriptional regulator
AM447_RS12135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM447_RS12140	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AM447_RS12145	COG1561	YicC-like family, N-terminal region
AM447_RS12165	COG1131	(ABC) transporter
AM447_RS12170	COG0842	Transport permease protein
AM447_RS12200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM447_RS12235	COG1519	Transferase
AM447_RS12240	COG1216	Glycosyl transferase, family 2
AM447_RS12245	COG0438	transferase activity, transferring glycosyl groups
AM447_RS12255	COG0859	PFAM glycosyl transferase family 9
AM447_RS12280	COG0859	PFAM glycosyl transferase family 9
AM447_RS12295	COG0156	8-amino-7-oxononanoate synthase activity
AM447_RS12305	COG0463	Glycosyl transferase, family 2
AM447_RS12310	COG2861	carbohydrate metabolic process
AM447_RS12315	COG4942	peptidase
AM447_RS12325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM447_RS12330	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM447_RS12350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM447_RS12360	COG2186	Transcriptional regulator
AM447_RS12380	COG3722	fumarate hydratase activity
AM447_RS12400	COG0625	glutathione transferase activity
AM447_RS12410	COG3276	selenocysteine insertion sequence binding
AM447_RS12415	COG1414	Transcriptional regulator
AM447_RS12420	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM447_RS12425	COG3977	Valine--pyruvate aminotransferase
AM447_RS12430	COG0366	Alpha amylase catalytic
AM447_RS12440	COG2992	FlgJ-related protein
AM447_RS12445	COG1609	Transcriptional regulator
AM447_RS12445	COG2207	Transcriptional regulator
AM447_RS12450	COG4214	carbohydrate transport
AM447_RS12460	COG4213	ABC transporter substrate-binding protein
AM447_RS12480	COG4682	membrane
AM447_RS12485	COG4682	membrane
AM447_RS12490	COG3274	enterobacterial common antigen metabolic process
AM447_RS12530	COG1278	Cold shock
AM447_RS12535	COG2944	sequence-specific DNA binding
AM447_RS12540	COG2814	Major facilitator Superfamily
AM447_RS12560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM447_RS12570	COG1609	Transcriptional regulator
AM447_RS12575	COG2885	chlorophyll binding
AM447_RS12580	COG0243	molybdopterin cofactor binding
AM447_RS12585	COG0456	acetyltransferase
AM447_RS12590	COG2818	Glycosylase
AM447_RS12595	COG5571	outer membrane autotransporter
AM447_RS12600	COG2223	nitrite transmembrane transporter activity
AM447_RS12630	COG0747	negative chemotaxis
AM447_RS12635	COG0601	transmembrane transport
AM447_RS12640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM447_RS12645	COG0444	Belongs to the ABC transporter superfamily
AM447_RS12650	COG4608	Belongs to the ABC transporter superfamily
AM447_RS12665	COG2894	cell division
AM447_RS12675	COG1215	transferase activity, transferring glycosyl groups
AM447_RS12680	COG0457	Tetratricopeptide repeat
AM447_RS12695	COG2194	sulfuric ester hydrolase activity
AM447_RS12725	COG1215	transferase activity, transferring glycosyl groups
AM447_RS12730	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM447_RS12735	COG3118	belongs to the thioredoxin family
AM447_RS12735	COG0457	Tetratricopeptide repeat
AM447_RS12740	COG2199	diguanylate cyclase activity
AM447_RS12740	COG2200	EAL domain
AM447_RS12750	COG0612	Peptidase, M16
AM447_RS12765	COG2982	Protein involved in outer membrane biogenesis
AM447_RS12770	COG0477	Major facilitator Superfamily
AM447_RS12780	COG1295	ribonuclease BN
AM447_RS12785	COG0583	DNA-binding transcription factor activity
AM447_RS12790	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS12795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM447_RS12805	COG1454	alcohol dehydrogenase
AM447_RS12815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM447_RS12820	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM447_RS12825	COG0671	phosphoesterase, PA-phosphatase related
AM447_RS12845	COG0589	response to stress
AM447_RS12855	COG0306	phosphate transporter
AM447_RS12860	COG2081	HI0933 family
AM447_RS12890	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AM447_RS12895	COG1196	nuclear chromosome segregation
AM447_RS12925	COG2239	Acts as a magnesium transporter
AM447_RS12940	COG1124	(ABC) transporter
AM447_RS12950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM447_RS12955	COG0601	transmembrane transport
AM447_RS12960	COG0747	negative chemotaxis
AM447_RS12970	COG3479	Phenolic acid decarboxylase
AM447_RS13010	COG0628	permease
AM447_RS13015	COG0477	Major facilitator Superfamily
AM447_RS13025	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM447_RS13040	COG3714	YhhN family
AM447_RS13050	COG3776	membrane
AM447_RS13055	COG0742	ribosomal rna small subunit methyltransferase
AM447_RS13060	COG0552	protein localization to endoplasmic reticulum
AM447_RS13065	COG2884	Cell division ATP-binding protein ftsE
AM447_RS13070	COG2177	Part of the ABC transporter FtsEX involved in
AM447_RS13085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM447_RS13095	COG0683	leucine binding
AM447_RS13105	COG0683	leucine binding
AM447_RS13110	COG0559	Belongs to the binding-protein-dependent transport system permease family
AM447_RS13160	COG0584	glycerophosphoryl diester phosphodiesterase
AM447_RS13170	COG0405	Gamma-glutamyltransferase
AM447_RS13175	COG1247	-acetyltransferase
AM447_RS13190	COG0673	inositol 2-dehydrogenase activity
AM447_RS13195	COG1741	Belongs to the pirin family
AM447_RS13200	COG1609	Transcriptional regulator
AM447_RS13205	COG3265	gluconokinase activity
AM447_RS13210	COG2610	gluconate transmembrane transporter activity
AM447_RS13220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM447_RS13245	COG0058	SHG alpha-glucan phosphorylase activity
AM447_RS13250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM447_RS13265	COG1349	DNA-binding transcription factor activity
AM447_RS13280	COG0058	SHG alpha-glucan phosphorylase activity
AM447_RS13285	COG1640	4-alpha-glucanotransferase
AM447_RS13290	COG2610	gluconate transmembrane transporter activity
AM447_RS13300	COG1040	competence protein
AM447_RS13325	COG1918	ferrous iron import across plasma membrane
AM447_RS13330	COG2183	response to ionizing radiation
AM447_RS13335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM447_RS13360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM447_RS13365	COG1011	Hydrolase
AM447_RS13375	COG0494	nUDIX hydrolase
AM447_RS13380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM447_RS13405	COG4796	Type ii and iii secretion system protein
AM447_RS13425	COG3266	domain, Protein
AM447_RS13430	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AM447_RS13435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM447_RS13460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM447_RS13465	COG0402	S-adenosylhomocysteine deaminase activity
AM447_RS13470	COG0738	Major facilitator superfamily
AM447_RS13495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM447_RS13500	COG1289	transmembrane transporter activity
AM447_RS13515	COG1765	OsmC-like protein
AM447_RS13520	COG3954	Phosphoribulokinase
AM447_RS13530	COG0429	hydrolase of the alpha beta-hydrolase fold
AM447_RS13540	COG0488	(ABC) transporter
AM447_RS13555	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM447_RS13560	COG1047	Peptidyl-prolyl cis-trans
AM447_RS13570	COG0545	Peptidyl-prolyl cis-trans isomerase
AM447_RS13575	COG2964	Protein conserved in bacteria
AM447_RS13630	COG0051	transcription antitermination factor activity, RNA binding
AM447_RS13655	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM447_RS13670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM447_RS13735	COG0201	protein transport
AM447_RS13760	COG0202	RNA polymerase activity
AM447_RS13775	COG0789	Transcriptional regulator
AM447_RS13780	COG3036	rescue of stalled ribosome
AM447_RS13810	COG0758	DNA mediated transformation
AM447_RS13820	COG0551	DNA topoisomerase type I activity
AM447_RS13840	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM447_RS13875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM447_RS13880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM447_RS13885	COG1309	transcriptional regulator
AM447_RS13910	COG4145	pantothenate transmembrane transporter activity
AM447_RS13915	COG3924	membrane
AM447_RS13920	COG0439	Biotin carboxylase
AM447_RS13925	COG0511	ligase activity, forming carbon-carbon bonds
AM447_RS13955	COG2199	diguanylate cyclase activity
AM447_RS13955	COG2200	EAL domain
AM447_RS13990	COG1077	Cell shape determining protein MreB Mrl
AM447_RS13995	COG1792	Involved in formation and maintenance of cell shape
AM447_RS14000	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM447_RS14010	COG1530	ribonuclease E activity
AM447_RS14015	COG3164	Protein of unknown function
AM447_RS14020	COG0312	modulator of DNA gyrase
AM447_RS14025	COG0583	DNA-binding transcription factor activity
AM447_RS14040	COG1289	transmembrane transporter activity
AM447_RS14045	COG2732	(Barnase) inhibitor
AM447_RS14080	COG0471	metal ion transport
AM447_RS14085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM447_RS14090	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM447_RS14115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM447_RS14120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM447_RS14125	COG3105	Protein conserved in bacteria
AM447_RS14130	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM447_RS14150	COG0625	glutathione transferase activity
AM447_RS14155	COG2969	positive regulation of protein catabolic process
AM447_RS14165	COG0493	'glutamate synthase
AM447_RS14175	COG1242	4 iron, 4 sulfur cluster binding
AM447_RS14180	COG2271	Major facilitator Superfamily
AM447_RS14185	COG1063	alcohol dehydrogenase
AM447_RS14190	COG1312	Catalyzes the dehydration of D-mannonate
AM447_RS14195	COG0784	Response regulator, receiver
AM447_RS14195	COG2198	Histidine kinase
AM447_RS14195	COG5002	protein histidine kinase activity
AM447_RS14200	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM447_RS14205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM447_RS14210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS14220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS14225	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM447_RS14230	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM447_RS14235	COG1137	ATPase activity
AM447_RS14240	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM447_RS14245	COG3117	lipopolysaccharide transmembrane transporter activity
AM447_RS14250	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM447_RS14260	COG0530	calcium, potassium:sodium antiporter activity
AM447_RS14270	COG1127	ABC transporter
AM447_RS14275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM447_RS14280	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM447_RS14285	COG2854	intermembrane phospholipid transfer
AM447_RS14290	COG3113	response to antibiotic
AM447_RS14295	COG5007	Belongs to the BolA IbaG family
AM447_RS14305	COG3423	Transcriptional regulator
AM447_RS14310	COG0142	geranyltranstransferase activity
AM447_RS14325	COG0697	spore germination
AM447_RS14335	COG2027	D-alanyl-D-alanine carboxypeptidase
AM447_RS14345	COG1534	Rna-binding protein
AM447_RS14360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM447_RS14365	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM447_RS14375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM447_RS14415	COG0195	Participates in both transcription termination and antitermination
AM447_RS14460	COG0814	amino acid
AM447_RS14465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM447_RS14470	COG0826	peptidase U32
AM447_RS14475	COG0826	peptidase U32
AM447_RS14480	COG3154	lipid carrier protein
AM447_RS14485	COG3153	acetyltransferase
AM447_RS14500	COG0693	protein deglycase activity
AM447_RS14505	COG0702	epimerase
AM447_RS14510	COG0701	Predicted permease
AM447_RS14515	COG2823	Periplasmic or secreted lipoprotein
AM447_RS14535	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM447_RS14540	COG2721	sulfolactate sulfo-lyase activity
AM447_RS14545	COG2271	Major facilitator Superfamily
AM447_RS14555	COG2084	Dehydrogenase
AM447_RS14560	COG1929	Belongs to the glycerate kinase type-1 family
AM447_RS14580	COG1741	Belongs to the pirin family
AM447_RS14585	COG0583	DNA-binding transcription factor activity
AM447_RS14590	COG3152	Membrane
AM447_RS14595	COG0435	Glutathione S-transferase
AM447_RS14600	COG2259	Doxx family
AM447_RS14610	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM447_RS14615	COG4575	ribosome binding
AM447_RS14620	COG1422	Protein of unknown function (DUF1090)
AM447_RS14630	COG0586	Pfam SNARE associated Golgi protein
AM447_RS14635	COG2186	Transcriptional regulator
AM447_RS14640	COG2271	Major facilitator Superfamily
AM447_RS14650	COG2721	sulfolactate sulfo-lyase activity
AM447_RS14665	COG0861	Integral membrane protein TerC family
AM447_RS14670	COG0673	inositol 2-dehydrogenase activity
AM447_RS14675	COG1451	nucleotide metabolic process
AM447_RS14695	COG1902	pentaerythritol trinitrate reductase activity
AM447_RS14695	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM447_RS14750	COG1695	Transcriptional regulator
AM447_RS14755	COG2375	cellular response to nickel ion
AM447_RS14770	COG1461	Dihydroxyacetone kinase
AM447_RS14775	COG2376	Dihydroxyacetone kinase
AM447_RS14845	COG3247	response to pH
AM447_RS14855	COG2205	protein histidine kinase activity
AM447_RS14855	COG2198	Histidine kinase
AM447_RS14855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM447_RS14855	COG0784	Response regulator, receiver
AM447_RS14860	COG2197	response regulator
AM447_RS14885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM447_RS14890	COG0358	DNA primase activity
AM447_RS14895	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM447_RS14965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM447_RS14980	COG4991	sh3 domain protein
AM447_RS14985	COG3025	triphosphatase activity
AM447_RS15005	COG2960	long-chain fatty acid transporting porin activity
AM447_RS15020	COG3384	dioxygenase
AM447_RS15025	COG0754	glutathionylspermidine amidase activity
AM447_RS15040	COG0494	nUDIX hydrolase
AM447_RS15045	COG3151	Protein conserved in bacteria
AM447_RS15050	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM447_RS15055	COG3150	esterase
AM447_RS15065	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM447_RS15070	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM447_RS15075	COG0642	Histidine kinase
AM447_RS15085	COG3111	PFAM Bacterial OB fold (BOF) protein
AM447_RS15090	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM447_RS15100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM447_RS15105	COG0204	Acyl-transferase
AM447_RS15110	COG2132	Multicopper oxidase
AM447_RS15115	COG1032	radical SAM domain protein
AM447_RS15125	COG0656	L-ascorbic acid biosynthetic process
AM447_RS15130	COG1979	alcohol dehydrogenase
AM447_RS15135	COG2207	Transcriptional regulator
AM447_RS15140	COG0586	Pfam SNARE associated Golgi protein
AM447_RS15145	COG0626	cystathionine gamma-synthase activity
AM447_RS15160	COG0848	biopolymer transport protein
AM447_RS15165	COG2211	Major facilitator Superfamily
AM447_RS15190	COG0625	glutathione transferase activity
AM447_RS15200	COG0754	glutathionylspermidine amidase activity
AM447_RS15205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM447_RS15225	COG0583	DNA-binding transcription factor activity
AM447_RS15230	COG0626	cystathionine gamma-synthase activity
AM447_RS15255	COG3121	Chaperone
AM447_RS15270	COG3121	Chaperone
AM447_RS15275	COG3121	Chaperone
AM447_RS15280	COG3188	usher protein
AM447_RS15310	COG1811	Na channel or pump
AM447_RS15320	COG1982	Orn Lys Arg decarboxylase major
AM447_RS15325	COG2211	Major facilitator Superfamily
AM447_RS15340	COG1194	a g-specific adenine glycosylase
AM447_RS15350	COG3171	Protein conserved in bacteria
AM447_RS15360	COG4214	carbohydrate transport
AM447_RS15375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM447_RS15390	COG0762	integral membrane protein
AM447_RS15395	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM447_RS15400	COG2805	Type II/IV secretion system protein
AM447_RS15420	COG0189	ligase activity
AM447_RS15425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM447_RS15430	COG2356	endonuclease I
AM447_RS15440	COG2814	Major facilitator Superfamily
AM447_RS15475	COG0501	Belongs to the peptidase M48B family
AM447_RS15480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM447_RS15495	COG0191	fructose-bisphosphate aldolase activity
AM447_RS15500	COG0668	transmembrane transport
AM447_RS15510	COG2968	Membrane
AM447_RS15525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM447_RS15530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM447_RS15550	COG0006	proline dipeptidase activity
AM447_RS15555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM447_RS15560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM447_RS15580	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS15585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM447_RS15605	COG2723	6-phospho-beta-galactosidase activity
AM447_RS15610	COG1737	Transcriptional regulator
AM447_RS15620	COG1272	protein, Hemolysin III
AM447_RS15630	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM447_RS15640	COG0716	FMN binding
AM447_RS15645	COG4974	Belongs to the 'phage' integrase family
AM447_RS15655	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM447_RS15675	COG1811	Na channel or pump
AM447_RS15685	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM447_RS15690	COG0583	DNA-binding transcription factor activity
AM447_RS15695	COG4942	peptidase
AM447_RS15705	COG2814	Major facilitator Superfamily
AM447_RS15720	COG0667	Aldo Keto reductase
AM447_RS15760	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM447_RS15765	COG1393	Belongs to the ArsC family
AM447_RS15780	COG1538	Outer membrane efflux protein
AM447_RS15785	COG1289	transmembrane transporter activity
AM447_RS15800	COG3592	Divergent 4Fe-4S mono-cluster
AM447_RS15805	COG2388	GCN5-related N-acetyl-transferase
AM447_RS15815	COG3539	Fimbrial protein
AM447_RS15820	COG3539	Fimbrial protein
AM447_RS15825	COG3539	Fimbrial protein
AM447_RS15830	COG3188	usher protein
AM447_RS15835	COG3121	Chaperone
AM447_RS15840	COG3539	Fimbrial protein
AM447_RS15850	COG4974	Belongs to the 'phage' integrase family
AM447_RS15855	COG0582	viral genome integration into host DNA
AM447_RS15870	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM447_RS15875	COG1846	Transcriptional regulator
AM447_RS15880	COG0697	spore germination
AM447_RS15930	COG0667	Aldo Keto reductase
AM447_RS15935	COG0814	amino acid
AM447_RS15950	COG0183	Belongs to the thiolase family
AM447_RS15965	COG0823	Involved in the tonB-independent uptake of proteins
AM447_RS15970	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS15975	COG2814	Major facilitator Superfamily
AM447_RS16005	COG3842	ATPase activity
AM447_RS16010	COG0395	ABC-type sugar transport system, permease component
AM447_RS16015	COG1175	transmembrane transport
AM447_RS16020	COG1917	Cupin 2, conserved barrel domain protein
AM447_RS16025	COG1794	racemase activity, acting on amino acids and derivatives
AM447_RS16030	COG0583	DNA-binding transcription factor activity
AM447_RS16040	COG1609	Transcriptional regulator
AM447_RS16045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS16050	COG2723	6-phospho-beta-galactosidase activity
AM447_RS16055	COG2186	Transcriptional regulator
AM447_RS16065	COG1609	Transcriptional regulator
AM447_RS16090	COG0667	Aldo Keto reductase
AM447_RS16100	COG0861	Integral membrane protein TerC family
AM447_RS16135	COG2165	general secretion pathway protein
AM447_RS16140	COG4795	General secretion pathway protein
AM447_RS16150	COG4967	type IV pilus modification protein PilV
AM447_RS16155	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM447_RS16160	COG1025	Belongs to the peptidase M16 family
AM447_RS16165	COG1074	ATP-dependent DNA helicase activity
AM447_RS16170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM447_RS16180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM447_RS16180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM447_RS16185	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM447_RS16190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM447_RS16220	COG4656	Part of a membrane complex involved in electron transport
AM447_RS16225	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS16225	COG1454	alcohol dehydrogenase
AM447_RS16255	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM447_RS16455	COG2885	chlorophyll binding
AM447_RS16485	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM447_RS16490	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM447_RS16495	COG2166	iron-sulfur cluster assembly
AM447_RS16500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM447_RS16510	COG0583	DNA-binding transcription factor activity
AM447_RS16515	COG2363	Small membrane protein
AM447_RS16525	COG1349	DNA-binding transcription factor activity
AM447_RS16545	COG0738	Major facilitator superfamily
AM447_RS16550	COG0235	Class ii aldolase
AM447_RS16555	COG1454	alcohol dehydrogenase
AM447_RS16570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM447_RS16585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM447_RS16590	COG2011	ABC-type metal ion transport system permease component
AM447_RS16595	COG1464	Belongs to the NlpA lipoprotein family
AM447_RS16605	COG0477	Major facilitator Superfamily
AM447_RS16615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM447_RS16620	COG1760	l-serine dehydratase
AM447_RS16625	COG0814	amino acid
AM447_RS16630	COG1611	Belongs to the LOG family
AM447_RS16645	COG3098	single-species biofilm formation
AM447_RS16650	COG0564	pseudouridine synthase activity
AM447_RS16655	COG0716	FMN binding
AM447_RS16660	COG2271	Major facilitator Superfamily
AM447_RS16665	COG4948	Mandelate Racemase Muconate Lactonizing
AM447_RS16670	COG4948	Mandelate Racemase Muconate Lactonizing
AM447_RS16675	COG1929	Belongs to the glycerate kinase type-1 family
AM447_RS16680	COG2205	protein histidine kinase activity
AM447_RS16680	COG4999	Histidine kinase
AM447_RS16680	COG3437	response regulator, receiver
AM447_RS16680	COG3850	Histidine kinase
AM447_RS16690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM447_RS16695	COG3956	TIGRFAM MazG family protein
AM447_RS16715	COG0602	queuosine metabolic process
AM447_RS16720	COG0720	synthase
AM447_RS16740	COG2234	aminopeptidase activity
AM447_RS16800	COG4942	peptidase
AM447_RS16800	COG1388	LysM domain
AM447_RS16805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM447_RS16830	COG0163	prenyltransferase activity
AM447_RS16835	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM447_RS16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM447_RS16880	COG4558	Periplasmic binding protein
AM447_RS16885	COG3720	iron ion transport
AM447_RS16905	COG0679	Auxin Efflux Carrier
AM447_RS16920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM447_RS16925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM447_RS16930	COG1121	(ABC) transporter
AM447_RS16935	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM447_RS16940	COG1609	Transcriptional regulator
AM447_RS16945	COG1940	carbohydrate kinase activity
AM447_RS16950	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM447_RS16955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS16960	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS16965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS16970	COG4580	involved in the transport of maltose and maltodextrins
AM447_RS16980	COG2723	6-phospho-beta-galactosidase activity
AM447_RS16990	COG0309	Hydrogenase expression formation protein (HypE)
AM447_RS16995	COG0409	Hydrogenase expression formation protein
AM447_RS17000	COG0298	carbon dioxide binding
AM447_RS17005	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM447_RS17025	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM447_RS17030	COG0651	ATP synthesis coupled electron transport
AM447_RS17035	COG0650	Formate hydrogenlyase subunit 4
AM447_RS17040	COG3261	NADH dehydrogenase
AM447_RS17040	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM447_RS17045	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM447_RS17050	COG3260	NADH ubiquinone oxidoreductase 20
AM447_RS17060	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM447_RS17070	COG2723	6-phospho-beta-galactosidase activity
AM447_RS17075	COG1263	PTS System
AM447_RS17075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM447_RS17080	COG1609	Transcriptional regulator
AM447_RS17085	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM447_RS17090	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM447_RS17095	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AM447_RS17125	COG1349	DNA-binding transcription factor activity
AM447_RS17130	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS17135	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS17145	COG3732	PTS system glucitol sorbitol-specific
AM447_RS17150	COG3730	PTS system glucitol sorbitol-specific
AM447_RS17155	COG2951	lytic endotransglycosylase activity
AM447_RS17160	COG1121	(ABC) transporter
AM447_RS17165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM447_RS17170	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM447_RS17175	COG1546	Belongs to the CinA family
AM447_RS17200	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM447_RS17230	COG2823	Periplasmic or secreted lipoprotein
AM447_RS17235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM447_RS17240	COG1238	metal cluster binding
AM447_RS17260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM447_RS17265	COG2814	Major facilitator Superfamily
AM447_RS17270	COG1566	PFAM secretion protein HlyD family protein
AM447_RS17275	COG1846	Transcriptional regulator
AM447_RS17285	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM447_RS17295	COG4176	ABC-type proline glycine betaine transport system permease component
AM447_RS17310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM447_RS17320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM447_RS17325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM447_RS17330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM447_RS17335	COG4575	ribosome binding
AM447_RS17355	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM447_RS17370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM447_RS17375	COG0640	Transcriptional regulator
AM447_RS17385	COG0583	DNA-binding transcription factor activity
AM447_RS17390	COG3284	Transcriptional regulator
AM447_RS17400	COG3539	Fimbrial protein
AM447_RS17405	COG3121	Chaperone
AM447_RS17425	COG3188	usher protein
AM447_RS17435	COG3539	Fimbrial protein
AM447_RS17440	COG2197	response regulator
AM447_RS17455	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS17465	COG0235	Class ii aldolase
AM447_RS17475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM447_RS17510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM447_RS17515	COG2207	Transcriptional regulator
AM447_RS17515	COG3708	Transcriptional regulator
AM447_RS17545	COG2867	negative regulation of translational initiation
AM447_RS17560	COG0497	DNA recombination
AM447_RS17580	COG4536	flavin adenine dinucleotide binding
AM447_RS17585	COG4137	Cytochrome C assembly protein
AM447_RS17590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM447_RS17625	COG2885	chlorophyll binding
AM447_RS17630	COG2199	diguanylate cyclase activity
AM447_RS17640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM447_RS17645	COG1605	Chorismate mutase
AM447_RS17645	COG0287	Prephenate dehydrogenase
AM447_RS17655	COG1605	Chorismate mutase
AM447_RS17655	COG0077	Prephenate dehydratase
AM447_RS17660	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM447_RS17665	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM447_RS17680	COG0542	response to heat
AM447_RS17705	COG0477	Major facilitator Superfamily
AM447_RS17710	COG5544	Lipoprotein
AM447_RS17715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM447_RS17725	COG3148	PFAM DTW domain containing protein
AM447_RS17730	COG3118	belongs to the thioredoxin family
AM447_RS17735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM447_RS17750	COG0513	Belongs to the DEAD box helicase family
AM447_RS17760	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM447_RS17770	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AM447_RS17775	COG3026	antisigma factor binding
AM447_RS17780	COG3086	response to oxidative stress
AM447_RS17820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM447_RS17870	COG1484	DNA-dependent DNA replication
AM447_RS17925	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM447_RS17930	COG0484	heat shock protein binding
AM447_RS17945	COG4372	Transposase
AM447_RS17950	COG3436	PFAM IS66 Orf2 family protein
AM447_RS17960	COG3179	chitinase
AM447_RS17995	COG5484	DNA packaging
AM447_RS17995	COG3728	DNA packaging
AM447_RS18085	COG1196	nuclear chromosome segregation
AM447_RS18145	COG0681	Belongs to the peptidase S26 family
AM447_RS18165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM447_RS18175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM447_RS18180	COG1737	Transcriptional regulator
AM447_RS18185	COG0560	Phosphoserine phosphatase
AM447_RS18200	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM447_RS18200	COG0047	phosphoribosylformylglycinamidine synthase activity
AM447_RS18210	COG2205	protein histidine kinase activity
AM447_RS18215	COG3170	Tfp pilus assembly protein FimV
AM447_RS18220	COG2204	response regulator
AM447_RS18225	COG0347	Belongs to the P(II) protein family
AM447_RS18230	COG1017	nitric oxide dioxygenase activity
AM447_RS18230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM447_RS18245	COG2259	Doxx family
AM447_RS18250	COG1940	carbohydrate kinase activity
AM447_RS18255	COG0457	Tetratricopeptide repeat
AM447_RS18260	COG2814	Major facilitator Superfamily
AM447_RS18260	COG0477	Major facilitator Superfamily
AM447_RS18265	COG2017	converts alpha-aldose to the beta-anomer
AM447_RS18270	COG2814	Major facilitator Superfamily
AM447_RS18275	COG3711	transcriptional antiterminator
AM447_RS18280	COG3683	transport system, periplasmic component
AM447_RS18285	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM447_RS18315	COG0822	iron-sulfur transferase activity
AM447_RS18335	COG0633	Ferredoxin
AM447_RS18340	COG2975	iron-sulfur cluster assembly
AM447_RS18360	COG2897	thiosulfate sulfurtransferase activity
AM447_RS18365	COG2373	Large extracellular alpha-helical protein
AM447_RS18370	COG4953	penicillin-binding protein 1C
AM447_RS18400	COG2976	Protein conserved in bacteria
AM447_RS18520	COG0758	DNA mediated transformation
AM447_RS18520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM447_RS18545	COG1645	bacterial-type flagellum-dependent swarming motility
AM447_RS18555	COG0517	IMP dehydrogenase activity
AM447_RS18555	COG0516	GMP reductase activity
AM447_RS18565	COG3119	arylsulfatase activity
AM447_RS18570	COG0641	radical SAM
AM447_RS18590	COG2200	EAL domain
AM447_RS18605	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM447_RS18620	COG2723	6-phospho-beta-galactosidase activity
AM447_RS18630	COG2233	PERMEase
AM447_RS18645	COG1393	Belongs to the ArsC family
AM447_RS18650	COG4783	chaperone-mediated protein folding
AM447_RS18655	COG0628	permease
AM447_RS18660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM447_RS18665	COG2716	regulation of RNA biosynthetic process
AM447_RS18675	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM447_RS18685	COG2321	neutral zinc metallopeptidase
AM447_RS18690	COG1444	tRNA N-acetyltransferase activity
AM447_RS18695	COG0400	carboxylic ester hydrolase activity
AM447_RS18710	COG1393	Belongs to the ArsC family
AM447_RS18715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM447_RS18725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM447_RS18725	COG0493	'glutamate synthase
AM447_RS18735	COG5342	invasion associated locus B
AM447_RS18740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM447_RS18745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM447_RS18755	COG4810	utilization protein
AM447_RS18845	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM447_RS18865	COG2837	iron assimilation
AM447_RS18875	COG4150	thiosulfate binding
AM447_RS18880	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM447_RS18885	COG4208	sulfate ABC transporter
AM447_RS18890	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM447_RS18900	COG4319	ketosteroid isomerase
AM447_RS18935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM447_RS18955	COG3530	Putative quorum-sensing-regulated virulence factor
AM447_RS18960	COG0385	Bile acid
AM447_RS18965	COG0583	DNA-binding transcription factor activity
AM447_RS18995	COG3415	Transposase
AM447_RS19000	COG3415	Transposase
AM447_RS19010	COG2200	EAL domain
AM447_RS19010	COG2199	diguanylate cyclase activity
AM447_RS19015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM447_RS19030	COG0667	Aldo Keto reductase
AM447_RS19035	COG3961	Belongs to the TPP enzyme family
AM447_RS19050	COG3279	Response regulator of the LytR AlgR family
AM447_RS19055	COG3275	phosphorelay sensor kinase activity
AM447_RS19065	COG0436	Aminotransferase
AM447_RS19070	COG2807	transmembrane transport
AM447_RS19075	COG0590	tRNA wobble adenosine to inosine editing
AM447_RS19080	COG0583	DNA-binding transcription factor activity
AM447_RS19100	COG2116	formate transmembrane transporter activity
AM447_RS19105	COG2853	Lipoprotein
AM447_RS19115	COG3691	Protein conserved in bacteria
AM447_RS19130	COG2062	phosphohistidine phosphatase, SixA
AM447_RS19155	COG0730	response to heat
AM447_RS19160	COG3101	peptidyl-lysine hydroxylation
AM447_RS19175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM447_RS19195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM447_RS19205	COG0586	Pfam SNARE associated Golgi protein
AM447_RS19215	COG0285	dihydrofolate synthase activity
AM447_RS19220	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM447_RS19225	COG1286	toxin biosynthetic process
AM447_RS19230	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM447_RS19235	COG0163	prenyltransferase activity
AM447_RS19255	COG4160	amino acid transport
AM447_RS19260	COG4598	ABC transporter
AM447_RS19270	COG1090	epimerase
AM447_RS19275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM447_RS19280	COG0625	glutathione transferase activity
AM447_RS19285	COG0625	glutathione transferase activity
AM447_RS19290	COG0622	Phosphoesterase
AM447_RS19295	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM447_RS19300	COG0280	phosphate acetyltransferase
AM447_RS19300	COG0857	belongs to the CobB CobQ family
AM447_RS19320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM447_RS19325	COG0471	metal ion transport
AM447_RS19325	COG0490	domain, Protein
AM447_RS19335	COG0436	Aminotransferase
AM447_RS19340	COG0583	DNA-binding transcription factor activity
AM447_RS19390	COG0839	Belongs to the complex I subunit 6 family
AM447_RS19400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM447_RS19405	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM447_RS19420	COG2153	protein acetylation
AM447_RS19425	COG1169	isochorismate synthase
AM447_RS19450	COG0318	PFAM AMP-dependent synthetase and ligase
AM447_RS19460	COG5464	transposase or invertase
AM447_RS19480	COG1414	Transcriptional regulator
AM447_RS19490	COG2271	Major facilitator Superfamily
AM447_RS19500	COG0247	lactate metabolic process
AM447_RS19510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM447_RS19515	COG2271	Major facilitator Superfamily
AM447_RS19530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM447_RS19560	COG2205	protein histidine kinase activity
AM447_RS19560	COG0784	Response regulator, receiver
AM447_RS19570	COG2198	Histidine kinase
AM447_RS19570	COG0642	Histidine kinase
AM447_RS19585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM447_RS19585	COG2169	Transcriptional regulator
AM447_RS19590	COG3145	DNA-N1-methyladenine dioxygenase activity
AM447_RS19595	COG4615	Cyclic peptide transporter
AM447_RS19600	COG2239	Acts as a magnesium transporter
AM447_RS19605	COG0659	secondary active sulfate transmembrane transporter activity
AM447_RS19620	COG0628	permease
AM447_RS19645	COG1349	DNA-binding transcription factor activity
AM447_RS19650	COG0494	nUDIX hydrolase
AM447_RS19670	COG1061	Type III restriction enzyme res subunit
AM447_RS19675	COG1187	pseudouridine synthase activity
AM447_RS19680	COG2814	Major facilitator Superfamily
AM447_RS19690	COG4172	Belongs to the ABC transporter superfamily
AM447_RS19695	COG4239	(ABC) transporter, permease
AM447_RS19700	COG4174	ABC transporter (Permease)
AM447_RS19705	COG4166	transmembrane transport
AM447_RS19710	COG2200	EAL domain
AM447_RS19715	COG0791	NLP P60 protein
AM447_RS19720	COG0671	phosphoesterase, PA-phosphatase related
AM447_RS19725	COG0523	cobalamin synthesis protein
AM447_RS19730	COG0246	Mannitol dehydrogenase
AM447_RS19735	COG1312	Catalyzes the dehydration of D-mannonate
AM447_RS19760	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS19760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS19765	COG1105	Belongs to the carbohydrate kinase PfkB family
AM447_RS19770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM447_RS19770	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM447_RS19770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM447_RS19780	COG2855	membrane
AM447_RS19790	COG0583	DNA-binding transcription factor activity
AM447_RS19795	COG0833	amino acid
AM447_RS19805	COG4771	TonB-dependent receptor
AM447_RS19820	COG2311	Membrane
AM447_RS19840	COG1129	ABC transporter
AM447_RS19850	COG2949	membrane
AM447_RS19865	COG1346	cytolysis
AM447_RS19875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM447_RS19880	COG3659	wide pore channel activity
AM447_RS19895	COG2723	6-phospho-beta-galactosidase activity
AM447_RS19905	COG1538	Outer membrane efflux protein
AM447_RS19910	COG0586	Pfam SNARE associated Golgi protein
AM447_RS19920	COG1686	Belongs to the peptidase S11 family
AM447_RS19930	COG0277	FAD linked oxidase domain protein
AM447_RS19935	COG1472	Belongs to the glycosyl hydrolase 3 family
AM447_RS19940	COG1732	Glycine betaine
AM447_RS19945	COG1174	glycine betaine transport
AM447_RS19950	COG1125	glycine betaine transport
AM447_RS19955	COG1174	glycine betaine transport
AM447_RS19965	COG3275	phosphorelay sensor kinase activity
AM447_RS19975	COG4807	Protein conserved in bacteria
AM447_RS19995	COG5455	response to cobalt ion
AM447_RS20000	COG0583	DNA-binding transcription factor activity
AM447_RS20005	COG2252	PERMEase
AM447_RS20015	COG0583	DNA-binding transcription factor activity
AM447_RS20030	COG0351	phosphomethylpyrimidine kinase
AM447_RS20035	COG1830	Aldolase
AM447_RS20070	COG1070	Carbohydrate kinase
AM447_RS20080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM447_RS20085	COG4948	Mandelate Racemase Muconate Lactonizing
AM447_RS20095	COG0601	transmembrane transport
AM447_RS20100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM447_RS20105	COG0444	Belongs to the ABC transporter superfamily
AM447_RS20110	COG4608	Belongs to the ABC transporter superfamily
AM447_RS20120	COG0826	peptidase U32
AM447_RS20125	COG0745	RESPONSE REGULATOR receiver
AM447_RS20130	COG2205	protein histidine kinase activity
AM447_RS20155	COG1301	dicarboxylic acid transport
AM447_RS20170	COG5002	protein histidine kinase activity
AM447_RS20175	COG0443	Heat shock 70 kDa protein
AM447_RS20180	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AM447_RS20195	COG2982	Protein involved in outer membrane biogenesis
AM447_RS20200	COG1253	flavin adenine dinucleotide binding
AM447_RS20330	COG0438	transferase activity, transferring glycosyl groups
AM447_RS20345	COG1215	transferase activity, transferring glycosyl groups
AM447_RS20365	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM447_RS20390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM447_RS20395	COG0583	DNA-binding transcription factor activity
AM447_RS20400	COG0531	amino acid
AM447_RS20405	COG0640	Transcriptional regulator
AM447_RS20410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM447_RS20415	COG2925	Exonuclease
AM447_RS20430	COG3344	reverse transcriptase
AM447_RS20440	COG1289	transmembrane transporter activity
AM447_RS20460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM447_RS20470	COG1942	4-Oxalocrotonate Tautomerase
AM447_RS20475	COG0583	DNA-binding transcription factor activity
AM447_RS20480	COG0095	Lipoate-protein ligase
AM447_RS20485	COG0477	Major facilitator Superfamily
AM447_RS20500	COG3300	MHYT domain
AM447_RS20500	COG5001	Diguanylate cyclase
AM447_RS20505	COG3615	Tellurite resistance protein tehB
AM447_RS20530	COG3706	GGDEF domain
AM447_RS20545	COG0534	Mate efflux family protein
AM447_RS20555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM447_RS20575	COG0604	alcohol dehydrogenase
AM447_RS20580	COG1309	transcriptional regulator
AM447_RS20585	COG0025	NhaP-type Na H and K H
AM447_RS20635	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM447_RS20645	COG1418	mRNA catabolic process
AM447_RS20650	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM447_RS20655	COG3727	T/G mismatch-specific endonuclease activity
AM447_RS20660	COG0697	spore germination
AM447_RS20665	COG2354	Protein conserved in bacteria
AM447_RS20695	COG0366	Alpha amylase catalytic
AM447_RS20700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM447_RS20710	COG0765	amino acid transport
AM447_RS20715	COG1126	abc transporter atp-binding protein
AM447_RS20720	COG2197	response regulator
AM447_RS20730	COG2197	response regulator
AM447_RS20765	COG3318	Belongs to the UPF0149 family
AM447_RS20765	COG3012	SEC-C Motif Domain Protein
AM447_RS20770	COG0814	amino acid
AM447_RS20780	COG1528	Iron-storage protein
AM447_RS20795	COG0477	Major facilitator Superfamily
AM447_RS20805	COG2211	Major facilitator Superfamily
AM447_RS20815	COG1528	Iron-storage protein
AM447_RS20825	COG1879	ABC-type sugar transport system periplasmic component
AM447_RS20835	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS20860	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AM447_RS20870	COG3102	Protein conserved in bacteria
AM447_RS20890	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM447_RS20895	COG1801	Protein of unknown function DUF72
AM447_RS20900	COG0582	viral genome integration into host DNA
AM447_RS21060	COG3772	lysozyme
AM447_RS21220	COG3344	reverse transcriptase
AM447_RS21235	COG1335	isochorismatase
AM447_RS21245	COG0494	nUDIX hydrolase
AM447_RS21270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM447_RS21280	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM447_RS21285	COG0739	heme binding
AM447_RS21290	COG1560	Kdo2-lipid A biosynthetic process
AM447_RS21300	COG1737	Transcriptional regulator
AM447_RS21315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM447_RS21320	COG0129	dihydroxy-acid dehydratase activity
AM447_RS21325	COG0800	Aldolase
AM447_RS21335	COG3141	response to X-ray
AM447_RS21340	COG2979	Protein of unknown function (DUF533)
AM447_RS21345	COG1770	oligopeptidase
AM447_RS21350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM447_RS21360	COG2372	response to copper ion
AM447_RS21365	COG1276	copper resistance
AM447_RS21380	COG2990	Protein conserved in bacteria
AM447_RS21405	COG3008	intermembrane lipid transfer
AM447_RS21410	COG2995	paraquat-inducible protein a
AM447_RS21415	COG1956	GAF domain-containing protein
AM447_RS21440	COG1414	Transcriptional regulator
AM447_RS21480	COG0768	penicillin binding
AM447_RS21485	COG2226	methyltransferase
AM447_RS21505	COG3716	PTS system mannose fructose sorbose family IID component
AM447_RS21510	COG3715	PTS system
AM447_RS21515	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM447_RS21515	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS21520	COG1253	flavin adenine dinucleotide binding
AM447_RS21525	COG2200	EAL domain
AM447_RS21530	COG1760	l-serine dehydratase
AM447_RS21550	COG0251	oxidation-reduction process
AM447_RS21555	COG1199	ATP-dependent helicase activity
AM447_RS21575	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM447_RS21585	COG2894	cell division
AM447_RS21600	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM447_RS21630	COG2719	SpoVR family
AM447_RS21650	COG1619	proteins homologs of microcin C7 resistance protein MccF
AM447_RS21660	COG4774	siderophore transport
AM447_RS21675	COG2308	Evidence 4 Homologs of previously reported genes of
AM447_RS21725	COG0583	DNA-binding transcription factor activity
AM447_RS21730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM447_RS21745	COG1882	Formate acetyltransferase
AM447_RS21775	COG0583	DNA-binding transcription factor activity
AM447_RS21805	COG0583	DNA-binding transcription factor activity
AM447_RS21820	COG3122	Protein conserved in bacteria
AM447_RS21850	COG2885	chlorophyll binding
AM447_RS21870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM447_RS21945	COG0012	GTP binding
AM447_RS21965	COG0659	secondary active sulfate transmembrane transporter activity
AM447_RS22000	COG2890	protein-(glutamine-N5) methyltransferase activity
AM447_RS22020	COG0387	Pfam Sodium calcium exchanger
AM447_RS22025	COG4572	Cation transport regulator
AM447_RS22030	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM447_RS22040	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM447_RS22045	COG3707	response regulator
AM447_RS22050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM447_RS22060	COG1116	anion transmembrane transporter activity
AM447_RS22065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM447_RS22065	COG2146	nitrite reductase [NAD(P)H] activity
AM447_RS22070	COG0243	molybdopterin cofactor binding
AM447_RS22075	COG4932	domain protein
AM447_RS22080	COG2197	response regulator
AM447_RS22085	COG3850	Histidine kinase
AM447_RS22090	COG2223	nitrite transmembrane transporter activity
AM447_RS22095	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM447_RS22100	COG1140	nitrate reductase beta subunit
AM447_RS22105	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM447_RS22110	COG2181	nitrate reductase activity
AM447_RS22120	COG1522	sequence-specific DNA binding
AM447_RS22165	COG0788	formyltetrahydrofolate deformylase activity
AM447_RS22175	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM447_RS22180	COG0745	RESPONSE REGULATOR receiver
AM447_RS22185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM447_RS22190	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM447_RS22195	COG1435	thymidine kinase activity
AM447_RS22200	COG1454	alcohol dehydrogenase
AM447_RS22200	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS22210	COG2095	MarC family integral membrane protein
AM447_RS22215	COG4166	transmembrane transport
AM447_RS22220	COG0601	transmembrane transport
AM447_RS22225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM447_RS22230	COG0444	Belongs to the ABC transporter superfamily
AM447_RS22240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM447_RS22260	COG2353	YceI-like domain
AM447_RS22265	COG2350	Protein conserved in bacteria
AM447_RS22275	COG3001	Fructosamine kinase
AM447_RS22285	COG1105	Belongs to the carbohydrate kinase PfkB family
AM447_RS22290	COG3137	Salt-induced outer membrane protein
AM447_RS22330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM447_RS22330	COG0072	phenylalanine-tRNA ligase activity
AM447_RS22350	COG0583	DNA-binding transcription factor activity
AM447_RS22370	COG0386	Belongs to the glutathione peroxidase family
AM447_RS22380	COG0791	NLP P60 protein
AM447_RS22390	COG4256	Hemin uptake protein
AM447_RS22395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM447_RS22405	COG0574	Belongs to the PEP-utilizing enzyme family
AM447_RS22405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM447_RS22415	COG0628	permease
AM447_RS22420	COG0277	FAD linked oxidase domain protein
AM447_RS22420	COG0247	lactate metabolic process
AM447_RS22425	COG2050	protein possibly involved in aromatic compounds catabolism
AM447_RS22430	COG2261	transglycosylase associated protein
AM447_RS22460	COG1120	ATPase activity
AM447_RS22465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM447_RS22475	COG0583	DNA-binding transcription factor activity
AM447_RS22500	COG1304	FMN binding
AM447_RS22505	COG1309	transcriptional regulator
AM447_RS22520	COG0316	Belongs to the HesB IscA family
AM447_RS22525	COG0719	Fe-S assembly protein
AM447_RS22530	COG0396	ATPase activity
AM447_RS22535	COG0719	Fe-S assembly protein
AM447_RS22550	COG1376	ErfK ybiS ycfS ynhG family protein
AM447_RS22575	COG1309	transcriptional regulator
AM447_RS22580	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AM447_RS22580	COG1082	Xylose isomerase domain protein TIM barrel
AM447_RS22585	COG2271	Major facilitator Superfamily
AM447_RS22590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM447_RS22600	COG1120	ATPase activity
AM447_RS22605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM447_RS22610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM447_RS22615	COG1414	Transcriptional regulator
AM447_RS22650	COG2814	Major facilitator Superfamily
AM447_RS22670	COG0583	DNA-binding transcription factor activity
AM447_RS22675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM447_RS22695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM447_RS22700	COG1116	anion transmembrane transporter activity
AM447_RS22705	COG4774	siderophore transport
AM447_RS22710	COG1120	ATPase activity
AM447_RS22715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM447_RS22720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM447_RS22740	COG0765	amino acid transport
AM447_RS22745	COG1126	abc transporter atp-binding protein
AM447_RS22775	COG1473	amidohydrolase
AM447_RS22780	COG3383	formate dehydrogenase (NAD+) activity
AM447_RS22785	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM447_RS22800	COG1175	transmembrane transport
AM447_RS22835	COG1857	crispr-associated protein
AM447_RS22845	COG1518	maintenance of DNA repeat elements
AM447_RS22850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM447_RS22860	COG3157	Type VI secretion system effector, Hcp
AM447_RS22890	COG4133	protoheme IX ABC transporter activity
AM447_RS22895	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM447_RS22900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM447_RS22915	COG1138	Cytochrome C-type biogenesis protein
AM447_RS22920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM447_RS22925	COG4235	cytochrome complex assembly
AM447_RS22925	COG3088	subunit of a heme lyase
AM447_RS22980	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS22985	COG2610	gluconate transmembrane transporter activity
AM447_RS22990	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM447_RS23000	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM447_RS23010	COG0583	DNA-binding transcription factor activity
AM447_RS23030	COG0277	FAD linked oxidase domain protein
AM447_RS23035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM447_RS23060	COG0402	S-adenosylhomocysteine deaminase activity
AM447_RS23105	COG2200	EAL domain
AM447_RS23185	COG2814	Major facilitator Superfamily
AM447_RS23190	COG1082	Xylose isomerase domain protein TIM barrel
AM447_RS23200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM447_RS23230	COG4608	Belongs to the ABC transporter superfamily
AM447_RS23235	COG0444	Belongs to the ABC transporter superfamily
AM447_RS23260	COG0346	lactoylglutathione lyase activity
AM447_RS23265	COG1349	DNA-binding transcription factor activity
AM447_RS23295	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AM447_RS23315	COG0300	oxidoreductase activity
AM447_RS23360	COG0307	riboflavin synthase, alpha
AM447_RS23365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM447_RS23370	COG2814	Major facilitator Superfamily
AM447_RS23375	COG0583	DNA-binding transcription factor activity
AM447_RS23385	COG2814	Major facilitator Superfamily
AM447_RS23400	COG0791	NLP P60 protein
AM447_RS23405	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM447_RS23415	COG0346	lactoylglutathione lyase activity
AM447_RS23420	COG1902	pentaerythritol trinitrate reductase activity
AM447_RS23425	COG1309	transcriptional regulator
AM447_RS23430	COG3313	Fe-S protein
AM447_RS23435	COG4989	oxidoreductase activity
AM447_RS23440	COG2032	superoxide dismutase activity
AM447_RS23445	COG1289	transmembrane transporter activity
AM447_RS23450	COG1566	PFAM secretion protein HlyD family protein
AM447_RS23490	COG3895	Periplasmic Protein
AM447_RS23505	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM447_RS23510	COG0625	glutathione transferase activity
AM447_RS23525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM447_RS23535	COG4659	FMN binding
AM447_RS23570	COG2723	6-phospho-beta-galactosidase activity
AM447_RS23580	COG0673	inositol 2-dehydrogenase activity
AM447_RS23590	COG2814	Major facilitator Superfamily
AM447_RS23610	COG3038	cytochrome b561
AM447_RS23630	COG0583	DNA-binding transcription factor activity
AM447_RS23635	COG3485	protocatechuate 3,4-dioxygenase
AM447_RS23640	COG3485	protocatechuate 3,4-dioxygenase
AM447_RS23645	COG5383	Protein conserved in bacteria
AM447_RS23650	COG2272	Belongs to the type-B carboxylesterase lipase family
AM447_RS23665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM447_RS23670	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM447_RS23675	COG1275	C4-dicarboxylate transporter malic acid transport protein
AM447_RS23680	COG0500	methyltransferase
AM447_RS23695	COG2207	Transcriptional regulator
AM447_RS23695	COG3708	Transcriptional regulator
AM447_RS23700	COG3135	benzoate transporter
AM447_RS23705	COG1396	sequence-specific DNA binding
AM447_RS23715	COG0826	peptidase U32
AM447_RS23735	COG1294	oxidase, subunit
AM447_RS23740	COG1271	oxidase subunit
AM447_RS23745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM447_RS23750	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM447_RS23755	COG3842	ATPase activity
AM447_RS23760	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM447_RS23765	COG1177	transmembrane transport
AM447_RS23770	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS23800	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS23805	COG0747	negative chemotaxis
AM447_RS23815	COG3238	Protein conserved in bacteria
AM447_RS23820	COG1247	-acetyltransferase
AM447_RS23830	COG2130	NADP-dependent
AM447_RS23845	COG3691	Protein conserved in bacteria
AM447_RS23850	COG1228	amidohydrolase
AM447_RS23855	COG4772	TonB-dependent receptor
AM447_RS23880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM447_RS23885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM447_RS23890	COG1473	amidohydrolase
AM447_RS23895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM447_RS23900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM447_RS23910	COG0765	amino acid transport
AM447_RS23915	COG1126	abc transporter atp-binding protein
AM447_RS23925	COG0625	glutathione transferase activity
AM447_RS23955	COG2211	Major facilitator Superfamily
AM447_RS23970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM447_RS23975	COG3842	ATPase activity
AM447_RS23980	COG1840	ABC-type Fe3 transport system, periplasmic component
AM447_RS23985	COG1178	ABC-type Fe3 transport system permease component
AM447_RS23990	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AM447_RS23995	COG2181	nitrate reductase activity
AM447_RS24000	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM447_RS24005	COG1140	nitrate reductase beta subunit
AM447_RS24010	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM447_RS24030	COG1414	Transcriptional regulator
AM447_RS24035	COG4948	Mandelate Racemase Muconate Lactonizing
AM447_RS24040	COG4829	muconolactone delta-isomerase
AM447_RS24045	COG3485	protocatechuate 3,4-dioxygenase
AM447_RS24055	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM447_RS24075	COG0243	molybdopterin cofactor binding
AM447_RS24075	COG3383	formate dehydrogenase (NAD+) activity
AM447_RS24080	COG3383	formate dehydrogenase (NAD+) activity
AM447_RS24080	COG0243	molybdopterin cofactor binding
AM447_RS24085	COG0437	4 iron, 4 sulfur cluster binding
AM447_RS24090	COG2864	formate dehydrogenase
AM447_RS24105	COG2326	polyphosphate kinase activity
AM447_RS24115	COG2814	Major facilitator Superfamily
AM447_RS24125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM447_RS24135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM447_RS24145	COG0747	negative chemotaxis
AM447_RS24150	COG1064	alcohol dehydrogenase
AM447_RS24165	COG0488	(ABC) transporter
AM447_RS24200	COG1028	Short-chain dehydrogenase reductase Sdr
AM447_RS24205	COG3729	General stress protein
AM447_RS24225	COG3685	Protein conserved in bacteria
AM447_RS24235	COG0366	Alpha amylase catalytic
AM447_RS24245	COG2323	membrane
AM447_RS24255	COG3111	PFAM Bacterial OB fold (BOF) protein
AM447_RS24260	COG1764	response to oxidative stress
AM447_RS24285	COG3781	membrane
AM447_RS24290	COG0243	molybdopterin cofactor binding
AM447_RS24295	COG0583	DNA-binding transcription factor activity
AM447_RS24300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS24325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM447_RS24330	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM447_RS24335	COG2814	Major facilitator Superfamily
AM447_RS24345	COG1285	pathogenesis
AM447_RS24350	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM447_RS24370	COG0519	Catalyzes the synthesis of GMP from XMP
AM447_RS24370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM447_RS24410	COG0596	Alpha beta hydrolase
AM447_RS24420	COG2205	protein histidine kinase activity
AM447_RS24435	COG0076	glutamate decarboxylase activity
AM447_RS24440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM447_RS24445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM447_RS24450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM447_RS24455	COG1116	anion transmembrane transporter activity
AM447_RS24460	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM447_RS24475	COG0673	inositol 2-dehydrogenase activity
AM447_RS24485	COG1609	Transcriptional regulator
AM447_RS24490	COG3706	GGDEF domain
AM447_RS24495	COG0402	S-adenosylhomocysteine deaminase activity
AM447_RS24500	COG1953	Uracil, thiamine, allantoin
AM447_RS24535	COG0596	Alpha beta hydrolase
AM447_RS24545	COG2207	Transcriptional regulator
AM447_RS24560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM447_RS24580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM447_RS24625	COG0765	amino acid transport
AM447_RS24635	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM447_RS24645	COG2070	2-Nitropropane dioxygenase
AM447_RS24650	COG0583	DNA-binding transcription factor activity
AM447_RS24660	COG1902	pentaerythritol trinitrate reductase activity
AM447_RS24665	COG4529	Protein conserved in bacteria
AM447_RS24670	COG0477	Major facilitator Superfamily
AM447_RS24700	COG2223	nitrite transmembrane transporter activity
AM447_RS24710	COG1609	Transcriptional regulator
AM447_RS24715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS24725	COG3037	sugar-specific permease SgaT UlaA
AM447_RS24730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM447_RS24740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM447_RS24745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM447_RS24745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM447_RS24745	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM447_RS24760	COG0583	DNA-binding transcription factor activity
AM447_RS24765	COG0583	DNA-binding transcription factor activity
AM447_RS24770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM447_RS24780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM447_RS24795	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM447_RS24805	COG1609	Transcriptional regulator
AM447_RS24835	COG1652	LysM domain
AM447_RS24865	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM447_RS24865	COG0456	acetyltransferase
AM447_RS24875	COG0667	Aldo Keto reductase
AM447_RS24880	COG0667	Aldo Keto reductase
AM447_RS24885	COG3386	PFAM SMP-30 Gluconolaconase
AM447_RS24890	COG0667	Aldo Keto reductase
AM447_RS24905	COG1473	amidohydrolase
AM447_RS24920	COG0251	oxidation-reduction process
AM447_RS24925	COG0583	DNA-binding transcription factor activity
AM447_RS24930	COG0626	cystathionine gamma-synthase activity
AM447_RS24935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM447_RS24940	COG0814	amino acid
AM447_RS24945	COG0583	DNA-binding transcription factor activity
AM447_RS24955	COG1294	oxidase, subunit
AM447_RS24960	COG1271	oxidase subunit
AM447_RS24970	COG3118	belongs to the thioredoxin family
AM447_RS25000	COG0583	DNA-binding transcription factor activity
AM447_RS25040	COG1929	Belongs to the glycerate kinase type-1 family
AM447_RS25045	COG3835	regulator
AM447_RS25055	COG0583	DNA-binding transcription factor activity
AM447_RS25065	COG2186	Transcriptional regulator
AM447_RS25070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM447_RS25070	COG1263	PTS System
AM447_RS25080	COG2814	Major facilitator Superfamily
AM447_RS25085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS25085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM447_RS25110	COG2819	hydrolase of the alpha beta superfamily
AM447_RS25115	COG5001	Diguanylate cyclase
AM447_RS25115	COG3300	MHYT domain
AM447_RS25150	COG3188	usher protein
AM447_RS25165	COG1649	PFAM Uncharacterised BCR, COG1649
AM447_RS25170	COG3550	peptidyl-serine autophosphorylation
AM447_RS25175	COG1396	sequence-specific DNA binding
AM447_RS25180	COG2351	hydroxyisourate hydrolase activity
AM447_RS25185	COG3648	Uricase
AM447_RS25185	COG3195	allantoin biosynthetic process
AM447_RS25190	COG2233	PERMEase
AM447_RS25220	COG2207	Transcriptional regulator
AM447_RS25235	COG4628	conserved protein (DUF2132)
AM447_RS25255	COG2011	ABC-type metal ion transport system permease component
AM447_RS25260	COG2070	2-Nitropropane dioxygenase
AM447_RS25270	COG0477	Major facilitator Superfamily
AM447_RS25340	COG2199	diguanylate cyclase activity
AM447_RS25355	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS25360	COG0583	DNA-binding transcription factor activity
AM447_RS25370	COG0039	L-malate dehydrogenase activity
AM447_RS25375	COG1349	DNA-binding transcription factor activity
AM447_RS25380	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM447_RS25385	COG3395	kinase activity
AM447_RS25395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM447_RS25400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM447_RS25405	COG2271	Major facilitator Superfamily
AM447_RS25430	COG4977	sequence-specific DNA binding
AM447_RS25440	COG0697	spore germination
AM447_RS25445	COG2814	Major facilitator Superfamily
AM447_RS25460	COG1129	ABC transporter
AM447_RS25475	COG0683	leucine binding
AM447_RS25480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM447_RS25515	COG2223	nitrite transmembrane transporter activity
AM447_RS25520	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM447_RS25535	COG1349	DNA-binding transcription factor activity
AM447_RS25540	COG2084	Dehydrogenase
AM447_RS25545	COG3395	kinase activity
AM447_RS25550	COG0235	Class ii aldolase
AM447_RS25555	COG3622	Belongs to the hyi family
AM447_RS25560	COG2610	gluconate transmembrane transporter activity
AM447_RS25565	COG2207	Transcriptional regulator
AM447_RS25565	COG3708	Transcriptional regulator
AM447_RS25580	COG2200	EAL domain
AM447_RS25585	COG1546	Belongs to the CinA family
AM447_RS25590	COG0071	Belongs to the small heat shock protein (HSP20) family
AM447_RS25605	COG2197	response regulator
AM447_RS25610	COG2135	peptidase activity
AM447_RS25615	COG2207	Transcriptional regulator
AM447_RS25630	COG4221	oxidoreductase activity
AM447_RS25635	COG1802	Transcriptional regulator
AM447_RS25640	COG0589	response to stress
AM447_RS25645	COG0246	Mannitol dehydrogenase
AM447_RS25650	COG2271	Major facilitator Superfamily
AM447_RS25665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM447_RS25680	COG0243	molybdopterin cofactor binding
AM447_RS25685	COG0437	4 iron, 4 sulfur cluster binding
AM447_RS25690	COG3302	dmso reductase anchor subunit
AM447_RS25705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM447_RS25710	COG1940	carbohydrate kinase activity
AM447_RS25715	COG0583	DNA-binding transcription factor activity
AM447_RS25720	COG2814	Major facilitator Superfamily
AM447_RS25725	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AM447_RS25735	COG3591	Belongs to the peptidase S1B family
AM447_RS25760	COG0628	permease
AM447_RS25790	COG0679	Auxin Efflux Carrier
AM447_RS25800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM447_RS25825	COG3290	protein histidine kinase activity
AM447_RS25830	COG4565	transcriptional regulatory protein
AM447_RS25855	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM447_RS25855	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM447_RS25880	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM447_RS25885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM447_RS25895	COG0183	Belongs to the thiolase family
AM447_RS25900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM447_RS25910	COG1414	Transcriptional regulator
AM447_RS25915	COG2840	Smr protein MutS2
AM447_RS25920	COG0583	DNA-binding transcription factor activity
AM447_RS25930	COG1473	amidohydrolase
AM447_RS25935	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM447_RS25950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM447_RS26055	COG1802	Transcriptional regulator
AM447_RS26055	COG4626	Terminase
AM447_RS26120	COG1403	HNH endonuclease
AM447_RS26125	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM447_RS26135	COG1846	Transcriptional regulator
AM447_RS26200	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM447_RS26215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM447_RS26230	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM447_RS26235	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM447_RS26255	COG0531	amino acid
AM447_RS26265	COG3136	membrane protein required for alginate biosynthesis
AM447_RS26270	COG0745	RESPONSE REGULATOR receiver
AM447_RS26280	COG2205	protein histidine kinase activity
AM447_RS26290	COG0114	fumarate hydratase activity
AM447_RS26295	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM447_RS26295	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM447_RS26300	COG1482	cell wall glycoprotein biosynthetic process
AM447_RS26305	COG5339	Protein conserved in bacteria
AM447_RS26310	COG1609	Transcriptional regulator
AM447_RS26315	COG1263	PTS System
AM447_RS26315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM447_RS26320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM447_RS26345	COG2391	methyltransferase activity
AM447_RS26350	COG0425	Belongs to the sulfur carrier protein TusA family
AM447_RS26355	COG5562	phage envelope protein
AM447_RS26360	COG0401	homolog of Blt101
AM447_RS26365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM447_RS26370	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS26375	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM447_RS26380	COG0477	Major facilitator Superfamily
AM447_RS26385	COG1113	amino acid transport
AM447_RS26390	COG2988	succinylglutamate desuccinylase activity
AM447_RS26395	COG3724	N-succinylarginine dihydrolase activity
AM447_RS26400	COG1012	belongs to the aldehyde dehydrogenase family
AM447_RS26405	COG3138	arginine N-succinyltransferase
AM447_RS26410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM447_RS26415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM447_RS26420	COG0667	Aldo Keto reductase
AM447_RS26425	COG0583	DNA-binding transcription factor activity
AM447_RS26450	COG4122	O-methyltransferase activity
AM447_RS26455	COG1643	Atp-dependent helicase
AM447_RS26470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM447_RS26475	COG3327	negative regulation of DNA-templated transcription, initiation
AM447_RS26480	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM447_RS26485	COG0183	Belongs to the thiolase family
AM447_RS26490	COG2050	protein possibly involved in aromatic compounds catabolism
AM447_RS26495	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM447_RS26500	COG1024	Enoyl-CoA hydratase
AM447_RS26505	COG1024	Enoyl-CoA hydratase
AM447_RS26510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM447_RS26515	COG2151	metal-sulfur cluster biosynthetic enzyme
AM447_RS26520	COG3396	Phenylacetate-CoA oxygenase
AM447_RS26525	COG3460	Phenylacetate-CoA oxygenase
AM447_RS26530	COG3396	Phenylacetate-CoA oxygenase
AM447_RS26535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM447_RS26575	COG3344	reverse transcriptase
AM447_RS26685	COG0210	DNA helicase
AM447_RS26695	COG2026	Addiction module toxin, RelE StbE family
AM447_RS26700	COG0675	Transposase, IS605 OrfB family
AM447_RS26715	COG0675	Transposase, IS605 OrfB family
AM447_RS26775	COG2963	transposase activity
AM447_RS26780	COG2801	Transposase and inactivated derivatives
AM447_RS26995	COG1484	DNA-dependent DNA replication
AM447_RS27050	COG0633	Ferredoxin
AM447_RS27310	COG5642	Protein of unknown function (DUF2384)
AM447_RS27315	COG5654	RES domain protein
AM447_RS27470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM447_RS27530	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM447_RS27580	COG3436	PFAM IS66 Orf2 family protein
AM447_RS27585	COG4372	Transposase
AM447_RS27640	COG1358	cellular component organization or biogenesis
AM447_RS27660	COG4245	von Willebrand factor, type A
AM447_RS27670	COG4245	von Willebrand factor, type A
AM447_RS27675	COG4245	von Willebrand factor, type A
AM447_RS27745	COG0789	Transcriptional regulator
AM447_RS27840	COG3039	Transposase
AM447_RS27875	COG1349	DNA-binding transcription factor activity
AM447_RS27895	COG1660	Displays ATPase and GTPase activities
AM447_RS27930	COG2826	transposase and inactivated derivatives, IS30 family
AM447_RS27960	COG1324	tolerance protein
AM447_RS27965	COG0673	inositol 2-dehydrogenase activity
AM447_RS27995	COG2826	transposase and inactivated derivatives, IS30 family
AM447_RS28035	COG2801	Transposase and inactivated derivatives
AM447_RS28040	COG3173	Aminoglycoside phosphotransferase
AM447_RS28045	COG0488	(ABC) transporter
AM447_RS28060	COG0482	sulfurtransferase activity
AM447_RS28130	COG2205	protein histidine kinase activity
AM447_RS28140	COG3436	PFAM IS66 Orf2 family protein
AM447_RS28145	COG4372	Transposase
AM447_RS28150	COG2205	protein histidine kinase activity
AM447_RS28155	COG0745	RESPONSE REGULATOR receiver
AM447_RS28160	COG1276	copper resistance
AM447_RS28165	COG2372	response to copper ion
AM447_RS28170	COG3667	copper resistance
AM447_RS28175	COG2132	Multicopper oxidase
AM447_RS28185	COG0739	heme binding
AM447_RS28215	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM447_RS28250	COG3436	PFAM IS66 Orf2 family protein
AM447_RS28255	COG4372	Transposase
AM447_RS28285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM447_RS28295	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM447_RS28310	COG5001	Diguanylate cyclase
AM447_RS28310	COG1716	ATPase activity
AM447_RS28315	COG2199	diguanylate cyclase activity
AM447_RS28315	COG2203	Gaf domain
AM447_RS28385	COG3344	reverse transcriptase
AM447_RS28545	COG5499	transcription regulator containing HTH domain
AM447_RS28765	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AM447_RS28790	COG3012	SEC-C Motif Domain Protein
AM447_RS28790	COG3318	Belongs to the UPF0149 family
AM447_RS28795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AM447_RS28835	COG2801	Transposase and inactivated derivatives
AM447_RS28845	COG3436	PFAM IS66 Orf2 family protein
AM447_RS28850	COG4372	Transposase
AM447_RS28960	COG4172	Belongs to the ABC transporter superfamily
AM447_RS28975	COG0601	transmembrane transport
AM447_RS28980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM447_RS29005	COG1595	DNA-templated transcription, initiation
AM447_RS29010	COG3712	iron ion homeostasis
AM447_RS29015	COG4772	TonB-dependent receptor
AM447_RS29020	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AM447_RS29025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM447_RS29030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM447_RS29035	COG1120	ATPase activity
AM447_RS29040	COG3436	PFAM IS66 Orf2 family protein
AM447_RS29070	COG1609	Transcriptional regulator
AM447_RS29080	COG2223	nitrite transmembrane transporter activity
AM447_RS29165	COG0071	Belongs to the small heat shock protein (HSP20) family
AM447_RS29170	COG0542	response to heat
AM447_RS29190	COG0501	Belongs to the peptidase M48B family
AM447_RS29205	COG2801	Transposase and inactivated derivatives
AM447_RS29270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM447_RS29300	COG0431	NADPH-dependent FMN reductase
AM447_RS29315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AM447_RS29335	COG0789	Transcriptional regulator
AM447_RS29365	COG3344	reverse transcriptase