locus-tag	class	description
AM458_RS00005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM458_RS00010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM458_RS00035	COG2732	(Barnase) inhibitor
AM458_RS00040	COG1289	transmembrane transporter activity
AM458_RS00055	COG0583	DNA-binding transcription factor activity
AM458_RS00060	COG0312	modulator of DNA gyrase
AM458_RS00065	COG3164	Protein of unknown function
AM458_RS00070	COG1530	ribonuclease E activity
AM458_RS00080	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM458_RS00085	COG1792	Involved in formation and maintenance of cell shape
AM458_RS00090	COG1077	Cell shape determining protein MreB Mrl
AM458_RS00100	COG2199	diguanylate cyclase activity
AM458_RS00100	COG2200	EAL domain
AM458_RS00130	COG0511	ligase activity, forming carbon-carbon bonds
AM458_RS00135	COG0439	Biotin carboxylase
AM458_RS00140	COG3924	membrane
AM458_RS00145	COG4145	pantothenate transmembrane transporter activity
AM458_RS00175	COG4626	Terminase
AM458_RS00175	COG1802	Transcriptional regulator
AM458_RS00265	COG3561	AntA/AntB antirepressor
AM458_RS00280	COG0582	viral genome integration into host DNA
AM458_RS00285	COG1309	transcriptional regulator
AM458_RS00290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM458_RS00295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM458_RS00335	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM458_RS00355	COG0551	DNA topoisomerase type I activity
AM458_RS00365	COG0758	DNA mediated transformation
AM458_RS00395	COG3036	rescue of stalled ribosome
AM458_RS00400	COG0789	Transcriptional regulator
AM458_RS00415	COG0202	RNA polymerase activity
AM458_RS00440	COG0201	protein transport
AM458_RS00505	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM458_RS00520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM458_RS00545	COG0051	transcription antitermination factor activity, RNA binding
AM458_RS00605	COG2964	Protein conserved in bacteria
AM458_RS00610	COG0545	Peptidyl-prolyl cis-trans isomerase
AM458_RS00620	COG1047	Peptidyl-prolyl cis-trans
AM458_RS00625	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM458_RS00645	COG0488	(ABC) transporter
AM458_RS00655	COG0429	hydrolase of the alpha beta-hydrolase fold
AM458_RS00665	COG3954	Phosphoribulokinase
AM458_RS00670	COG1765	OsmC-like protein
AM458_RS00685	COG1289	transmembrane transporter activity
AM458_RS00690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM458_RS00715	COG0738	Major facilitator superfamily
AM458_RS00720	COG0402	S-adenosylhomocysteine deaminase activity
AM458_RS00725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM458_RS00750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM458_RS00755	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AM458_RS00760	COG3266	domain, Protein
AM458_RS00780	COG4796	Type ii and iii secretion system protein
AM458_RS00805	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM458_RS00810	COG0494	nUDIX hydrolase
AM458_RS00820	COG1011	Hydrolase
AM458_RS00825	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM458_RS00850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM458_RS00855	COG2183	response to ionizing radiation
AM458_RS00860	COG1918	ferrous iron import across plasma membrane
AM458_RS00885	COG1040	competence protein
AM458_RS00895	COG2610	gluconate transmembrane transporter activity
AM458_RS00900	COG1640	4-alpha-glucanotransferase
AM458_RS00905	COG0058	SHG alpha-glucan phosphorylase activity
AM458_RS00920	COG1349	DNA-binding transcription factor activity
AM458_RS00935	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM458_RS00950	COG0058	SHG alpha-glucan phosphorylase activity
AM458_RS00975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM458_RS00985	COG2610	gluconate transmembrane transporter activity
AM458_RS00990	COG3265	gluconokinase activity
AM458_RS00995	COG1609	Transcriptional regulator
AM458_RS01000	COG1741	Belongs to the pirin family
AM458_RS01005	COG0673	inositol 2-dehydrogenase activity
AM458_RS01015	COG1247	-acetyltransferase
AM458_RS01020	COG0405	Gamma-glutamyltransferase
AM458_RS01030	COG0584	glycerophosphoryl diester phosphodiesterase
AM458_RS01080	COG0559	Belongs to the binding-protein-dependent transport system permease family
AM458_RS01085	COG0683	leucine binding
AM458_RS01100	COG0683	leucine binding
AM458_RS01110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM458_RS01125	COG2177	Part of the ABC transporter FtsEX involved in
AM458_RS01130	COG2884	Cell division ATP-binding protein ftsE
AM458_RS01135	COG0552	protein localization to endoplasmic reticulum
AM458_RS01140	COG0742	ribosomal rna small subunit methyltransferase
AM458_RS01145	COG3776	membrane
AM458_RS01155	COG3714	YhhN family
AM458_RS01170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM458_RS01180	COG0477	Major facilitator Superfamily
AM458_RS01185	COG0628	permease
AM458_RS01225	COG3479	Phenolic acid decarboxylase
AM458_RS01240	COG0747	negative chemotaxis
AM458_RS01245	COG0601	transmembrane transport
AM458_RS01250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM458_RS01260	COG1124	(ABC) transporter
AM458_RS01270	COG2239	Acts as a magnesium transporter
AM458_RS01275	COG2081	HI0933 family
AM458_RS01280	COG0306	phosphate transporter
AM458_RS01290	COG0589	response to stress
AM458_RS01310	COG0671	phosphoesterase, PA-phosphatase related
AM458_RS01315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM458_RS01320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM458_RS01330	COG1454	alcohol dehydrogenase
AM458_RS01340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM458_RS01345	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS01350	COG0583	DNA-binding transcription factor activity
AM458_RS01355	COG1295	ribonuclease BN
AM458_RS01360	COG0477	Major facilitator Superfamily
AM458_RS01365	COG2982	Protein involved in outer membrane biogenesis
AM458_RS01380	COG0612	Peptidase, M16
AM458_RS01395	COG2200	EAL domain
AM458_RS01395	COG2199	diguanylate cyclase activity
AM458_RS01400	COG3118	belongs to the thioredoxin family
AM458_RS01400	COG0457	Tetratricopeptide repeat
AM458_RS01405	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM458_RS01410	COG1215	transferase activity, transferring glycosyl groups
AM458_RS01440	COG2194	sulfuric ester hydrolase activity
AM458_RS01455	COG0457	Tetratricopeptide repeat
AM458_RS01460	COG1215	transferase activity, transferring glycosyl groups
AM458_RS01485	COG4608	Belongs to the ABC transporter superfamily
AM458_RS01490	COG0444	Belongs to the ABC transporter superfamily
AM458_RS01495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM458_RS01500	COG0601	transmembrane transport
AM458_RS01505	COG0747	negative chemotaxis
AM458_RS01545	COG2223	nitrite transmembrane transporter activity
AM458_RS01550	COG5571	outer membrane autotransporter
AM458_RS01555	COG2818	Glycosylase
AM458_RS01560	COG0456	acetyltransferase
AM458_RS01565	COG0243	molybdopterin cofactor binding
AM458_RS01570	COG2885	chlorophyll binding
AM458_RS01575	COG1609	Transcriptional regulator
AM458_RS01585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM458_RS01610	COG2814	Major facilitator Superfamily
AM458_RS01615	COG2944	sequence-specific DNA binding
AM458_RS01620	COG1278	Cold shock
AM458_RS01655	COG3274	enterobacterial common antigen metabolic process
AM458_RS01660	COG4682	membrane
AM458_RS01665	COG4682	membrane
AM458_RS01685	COG4213	ABC transporter substrate-binding protein
AM458_RS01695	COG4214	carbohydrate transport
AM458_RS01700	COG2207	Transcriptional regulator
AM458_RS01700	COG1609	Transcriptional regulator
AM458_RS01705	COG2992	FlgJ-related protein
AM458_RS01715	COG0366	Alpha amylase catalytic
AM458_RS01720	COG3977	Valine--pyruvate aminotransferase
AM458_RS01725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM458_RS01730	COG1414	Transcriptional regulator
AM458_RS01735	COG3276	selenocysteine insertion sequence binding
AM458_RS01745	COG0625	glutathione transferase activity
AM458_RS01750	COG1566	PFAM secretion protein HlyD family protein
AM458_RS01770	COG3722	fumarate hydratase activity
AM458_RS01790	COG2186	Transcriptional regulator
AM458_RS01800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM458_RS01820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM458_RS01825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM458_RS01835	COG4942	peptidase
AM458_RS01840	COG2861	carbohydrate metabolic process
AM458_RS01845	COG0463	Glycosyl transferase, family 2
AM458_RS01855	COG0156	8-amino-7-oxononanoate synthase activity
AM458_RS01870	COG0859	PFAM glycosyl transferase family 9
AM458_RS01895	COG0859	PFAM glycosyl transferase family 9
AM458_RS01905	COG0438	transferase activity, transferring glycosyl groups
AM458_RS01910	COG1216	Glycosyl transferase, family 2
AM458_RS01915	COG1519	Transferase
AM458_RS01950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM458_RS01975	COG0842	Transport permease protein
AM458_RS01980	COG1131	(ABC) transporter
AM458_RS02000	COG1561	YicC-like family, N-terminal region
AM458_RS02005	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AM458_RS02010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM458_RS02010	COG2169	Transcriptional regulator
AM458_RS02020	COG2860	membrane
AM458_RS02040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM458_RS02045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM458_RS02050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM458_RS02055	COG1494	fructose-1,6-bisphosphatase
AM458_RS02065	COG3152	Membrane
AM458_RS02090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM458_RS02110	COG0786	glutamate:sodium symporter activity
AM458_RS02115	COG2233	PERMEase
AM458_RS02120	COG2982	Protein involved in outer membrane biogenesis
AM458_RS02125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM458_RS02125	COG1263	PTS System
AM458_RS02130	COG1486	melibiose metabolic process
AM458_RS02140	COG1501	Belongs to the glycosyl hydrolase 31 family
AM458_RS02145	COG2211	Major facilitator Superfamily
AM458_RS02180	COG1064	alcohol dehydrogenase
AM458_RS02190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AM458_RS02205	COG1464	Belongs to the NlpA lipoprotein family
AM458_RS02230	COG0583	DNA-binding transcription factor activity
AM458_RS02265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM458_RS02275	COG2814	Major facilitator Superfamily
AM458_RS02285	COG1263	PTS System
AM458_RS02285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM458_RS02290	COG0697	spore germination
AM458_RS02305	COG2828	Protein conserved in bacteria
AM458_RS02310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM458_RS02315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AM458_RS02320	COG0583	DNA-binding transcription factor activity
AM458_RS02325	COG3384	dioxygenase
AM458_RS02335	COG1609	Transcriptional regulator
AM458_RS02345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS02345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS02350	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM458_RS02355	COG4580	involved in the transport of maltose and maltodextrins
AM458_RS02390	COG2188	Transcriptional regulator
AM458_RS02435	COG2271	Major facilitator Superfamily
AM458_RS02445	COG2197	response regulator
AM458_RS02450	COG0440	acetolactate synthase activity
AM458_RS02455	COG0028	Belongs to the TPP enzyme family
AM458_RS02480	COG2814	Major facilitator Superfamily
AM458_RS02485	COG0583	DNA-binding transcription factor activity
AM458_RS02490	COG2610	gluconate transmembrane transporter activity
AM458_RS02510	COG2149	membrane
AM458_RS02525	COG2188	Transcriptional regulator
AM458_RS02535	COG3645	SOS response
AM458_RS02550	COG5645	(Lipo)protein
AM458_RS02555	COG0823	Involved in the tonB-independent uptake of proteins
AM458_RS02560	COG2271	Major facilitator Superfamily
AM458_RS02570	COG0800	Aldolase
AM458_RS02575	COG3734	2-keto-3-deoxy-galactonokinase
AM458_RS02580	COG2186	Transcriptional regulator
AM458_RS02595	COG0561	phosphatase activity
AM458_RS02600	COG0187	DNA topoisomerase II activity
AM458_RS02635	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM458_RS02670	COG2091	lysine biosynthetic process via aminoadipic acid
AM458_RS02675	COG0431	NADPH-dependent FMN reductase
AM458_RS02680	COG2252	PERMEase
AM458_RS02690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM458_RS02695	COG0363	glucosamine-6-phosphate deaminase activity
AM458_RS02700	COG2382	esterase
AM458_RS02715	COG0704	Plays a role in the regulation of phosphate uptake
AM458_RS02720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM458_RS02725	COG0581	inorganic phosphate transmembrane transporter activity
AM458_RS02730	COG0573	inorganic phosphate transmembrane transporter activity
AM458_RS02735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM458_RS02740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM458_RS02790	COG3312	ion transport
AM458_RS02805	COG0716	FMN binding
AM458_RS02810	COG1522	sequence-specific DNA binding
AM458_RS02840	COG1129	ABC transporter
AM458_RS02845	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS02855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM458_RS02860	COG1609	Transcriptional regulator
AM458_RS02865	COG0477	Major facilitator Superfamily
AM458_RS02870	COG2186	Transcriptional regulator
AM458_RS02900	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM458_RS02910	COG3084	Protein conserved in bacteria
AM458_RS02915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM458_RS02925	COG0204	Acyl-transferase
AM458_RS02955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM458_RS02965	COG3852	Histidine kinase
AM458_RS02985	COG1011	Hydrolase
AM458_RS03000	COG0456	acetyltransferase
AM458_RS03005	COG0657	acetylesterase activity
AM458_RS03010	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM458_RS03025	COG2864	formate dehydrogenase
AM458_RS03030	COG0437	4 iron, 4 sulfur cluster binding
AM458_RS03055	COG0205	6-phosphofructokinase activity
AM458_RS03115	COG2211	Major facilitator Superfamily
AM458_RS03125	COG1454	alcohol dehydrogenase
AM458_RS03130	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS03135	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS03140	COG1129	ABC transporter
AM458_RS03185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM458_RS03190	COG2258	MOSC domain
AM458_RS03195	COG2205	protein histidine kinase activity
AM458_RS03200	COG0745	RESPONSE REGULATOR receiver
AM458_RS03205	COG3678	ATP-independent chaperone mediated protein folding
AM458_RS03225	COG1575	Belongs to the MenA family. Type 1 subfamily
AM458_RS03240	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM458_RS03245	COG1609	Transcriptional regulator
AM458_RS03250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM458_RS03265	COG0626	cystathionine gamma-synthase activity
AM458_RS03270	COG0527	aspartate kinase activity
AM458_RS03270	COG0460	homoserine dehydrogenase
AM458_RS03280	COG0737	Belongs to the 5'-nucleotidase family
AM458_RS03290	COG0583	DNA-binding transcription factor activity
AM458_RS03300	COG0697	spore germination
AM458_RS03305	COG0371	Dehydrogenase
AM458_RS03315	COG2207	Transcriptional regulator
AM458_RS03320	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM458_RS03335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM458_RS03360	COG0583	DNA-binding transcription factor activity
AM458_RS03435	COG3085	chromosome segregation
AM458_RS03455	COG3978	acetolactate synthase activity
AM458_RS03470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM458_RS03475	COG0583	DNA-binding transcription factor activity
AM458_RS03485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM458_RS03490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM458_RS03500	COG1811	Na channel or pump
AM458_RS03530	COG3118	belongs to the thioredoxin family
AM458_RS03540	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM458_RS03545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM458_RS03555	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM458_RS03560	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM458_RS03565	COG1088	dTDP-glucose 4,6-dehydratase activity
AM458_RS03570	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM458_RS03575	COG0456	acetyltransferase
AM458_RS03580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM458_RS03585	COG2244	polysaccharide biosynthetic process
AM458_RS03630	COG3071	HemY protein
AM458_RS03635	COG2959	enzyme of heme biosynthesis
AM458_RS03650	COG3072	Adenylate cyclase
AM458_RS03680	COG1011	Hydrolase
AM458_RS03685	COG0210	DNA helicase
AM458_RS03720	COG1280	lysine exporter protein (LysE YggA)
AM458_RS03730	COG1280	lysine exporter protein (LysE YggA)
AM458_RS03735	COG2267	carboxylic ester hydrolase activity
AM458_RS03740	COG0561	phosphatase activity
AM458_RS03745	COG0697	spore germination
AM458_RS03750	COG0583	DNA-binding transcription factor activity
AM458_RS03780	COG3165	ubiquinone biosynthetic process from chorismate
AM458_RS03800	COG0805	protein transport
AM458_RS03845	COG1739	Uncharacterized protein family UPF0029
AM458_RS03855	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AM458_RS03890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM458_RS03940	COG0250	Participates in transcription elongation, termination and antitermination
AM458_RS03980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM458_RS03985	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM458_RS03995	COG3706	GGDEF domain
AM458_RS04015	COG2104	thiamine diphosphate biosynthetic process
AM458_RS04020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM458_RS04035	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AM458_RS04070	COG3678	ATP-independent chaperone mediated protein folding
AM458_RS04075	COG4191	Histidine kinase
AM458_RS04085	COG0151	Belongs to the GarS family
AM458_RS04130	COG0456	acetyltransferase
AM458_RS04140	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM458_RS04170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM458_RS04225	COG0527	aspartate kinase activity
AM458_RS04245	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM458_RS04255	COG0251	oxidation-reduction process
AM458_RS04330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM458_RS04340	COG0534	Mate efflux family protein
AM458_RS04345	COG3237	CsbD-like
AM458_RS04350	COG0735	belongs to the Fur family
AM458_RS04360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM458_RS04375	COG0305	Participates in initiation and elongation during chromosome replication
AM458_RS04380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM458_RS04395	COG0432	Pfam Uncharacterised protein family UPF0047
AM458_RS04400	COG2315	Protein conserved in bacteria
AM458_RS04420	COG0741	lytic transglycosylase activity
AM458_RS04425	COG4771	TonB-dependent receptor
AM458_RS04445	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM458_RS04460	COG0483	inositol monophosphate 1-phosphatase activity
AM458_RS04465	COG1609	Transcriptional regulator
AM458_RS04470	COG1234	tRNA 3'-trailer cleavage
AM458_RS04505	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM458_RS04515	COG0789	Transcriptional regulator
AM458_RS04520	COG0625	glutathione transferase activity
AM458_RS04525	COG2252	PERMEase
AM458_RS04530	COG0025	NhaP-type Na H and K H
AM458_RS04535	COG0583	DNA-binding transcription factor activity
AM458_RS04540	COG1380	Effector of murein hydrolase LrgA
AM458_RS04545	COG1346	cytolysis
AM458_RS04550	COG3539	Fimbrial protein
AM458_RS04580	COG3162	membrane
AM458_RS04590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM458_RS04600	COG1301	dicarboxylic acid transport
AM458_RS04605	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM458_RS04640	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS04645	COG1129	ABC transporter
AM458_RS04650	COG4191	Histidine kinase
AM458_RS04650	COG0784	Response regulator, receiver
AM458_RS04660	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM458_RS04670	COG3454	Phosphonate metabolism
AM458_RS04675	COG4778	phosphonate C-P lyase system protein PhnL
AM458_RS04680	COG4107	phosphonate C-P lyase system protein PhnK
AM458_RS04685	COG3627	carbon phosphorus lyase activity
AM458_RS04690	COG3626	phosphonate metabolism
AM458_RS04695	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM458_RS04700	COG3624	Phosphonate C-P lyase system protein PhnG
AM458_RS04705	COG2188	Transcriptional regulator
AM458_RS04710	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AM458_RS04715	COG2824	Alkylphosphonate utilization operon protein PhnA
AM458_RS04730	COG2169	Transcriptional regulator
AM458_RS04740	COG1486	melibiose metabolic process
AM458_RS04775	COG0861	Integral membrane protein TerC family
AM458_RS04795	COG1215	transferase activity, transferring glycosyl groups
AM458_RS04800	COG1649	PFAM Uncharacterised BCR, COG1649
AM458_RS04800	COG0726	polysaccharide deacetylase
AM458_RS04805	COG0457	Tetratricopeptide repeat
AM458_RS04835	COG1309	transcriptional regulator
AM458_RS04850	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM458_RS04855	COG1027	Aspartate ammonia-lyase
AM458_RS04865	COG3030	protein affecting phage T7 exclusion by the F plasmid
AM458_RS04870	COG0531	amino acid
AM458_RS04940	COG1509	lysine 2,3-aminomutase activity
AM458_RS04955	COG5510	response to toxic substance
AM458_RS04960	COG2076	Multidrug Resistance protein
AM458_RS04980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM458_RS04985	COG1053	succinate dehydrogenase
AM458_RS05000	COG1511	domain protein
AM458_RS05000	COG3264	Mechanosensitive ion channel
AM458_RS05025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM458_RS05050	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM458_RS05055	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM458_RS05055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM458_RS05060	COG0802	atpase or kinase
AM458_RS05065	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM458_RS05085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM458_RS05090	COG0330	HflC and HflK could
AM458_RS05095	COG0330	HflC and HflK could
AM458_RS05105	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AM458_RS05120	COG0557	exoribonuclease II activity
AM458_RS05125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM458_RS05130	COG1960	acyl-CoA dehydrogenase activity
AM458_RS05140	COG3650	response to hydrogen peroxide
AM458_RS05145	COG1073	alpha beta
AM458_RS05205	COG2965	DNA replication, synthesis of RNA primer
AM458_RS05210	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM458_RS05220	COG3061	Opacity-associated protein A
AM458_RS05225	COG0545	Peptidyl-prolyl cis-trans isomerase
AM458_RS05230	COG1113	amino acid transport
AM458_RS05240	COG0697	spore germination
AM458_RS05250	COG0702	epimerase
AM458_RS05255	COG1733	regulation of RNA biosynthetic process
AM458_RS05270	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM458_RS05285	COG1253	flavin adenine dinucleotide binding
AM458_RS05295	COG0729	surface antigen
AM458_RS05300	COG2911	Protein conserved in bacteria
AM458_RS05305	COG2105	PFAM AIG2 family protein
AM458_RS05325	COG1879	ABC-type sugar transport system periplasmic component
AM458_RS05330	COG1129	ABC transporter
AM458_RS05335	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS05340	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS05350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM458_RS05370	COG0312	modulator of DNA gyrase
AM458_RS05405	COG3964	amidohydrolase
AM458_RS05420	COG2706	6-phosphogluconolactonase activity
AM458_RS05425	COG3711	transcriptional antiterminator
AM458_RS05425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS05430	COG3077	Addiction module antitoxin, RelB DinJ family
AM458_RS05435	COG2026	Addiction module toxin, RelE StbE family
AM458_RS05440	COG0602	queuosine metabolic process
AM458_RS05460	COG1486	melibiose metabolic process
AM458_RS05465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS05470	COG0366	Alpha amylase catalytic
AM458_RS05475	COG1263	PTS System
AM458_RS05475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM458_RS05520	COG2731	YhcH YjgK YiaL family protein
AM458_RS05525	COG2222	sugar isomerase
AM458_RS05530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM458_RS05535	COG1228	amidohydrolase
AM458_RS05540	COG1288	antiporter activity
AM458_RS05545	COG2188	Transcriptional regulator
AM458_RS05570	COG0525	valine-tRNA ligase activity
AM458_RS05575	COG2927	DNA polymerase III (CHI subunit)
AM458_RS05590	COG0795	lipopolysaccharide-transporting ATPase activity
AM458_RS05595	COG0795	lipopolysaccharide-transporting ATPase activity
AM458_RS05600	COG0433	COG0433 Predicted ATPase
AM458_RS05615	COG3718	enzyme involved in inositol metabolism
AM458_RS05655	COG0837	glucose binding
AM458_RS05655	COG1737	Transcriptional regulator
AM458_RS05660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM458_RS05665	COG3962	Belongs to the TPP enzyme family
AM458_RS05675	COG1082	Xylose isomerase domain protein TIM barrel
AM458_RS05685	COG1653	transport
AM458_RS05690	COG3842	ATPase activity
AM458_RS05695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM458_RS05700	COG0395	ABC-type sugar transport system, permease component
AM458_RS05705	COG1175	transmembrane transport
AM458_RS05710	COG1064	alcohol dehydrogenase
AM458_RS05715	COG0659	secondary active sulfate transmembrane transporter activity
AM458_RS05720	COG0288	reversible hydration of carbon dioxide
AM458_RS05735	COG0582	viral genome integration into host DNA
AM458_RS05850	COG3507	Belongs to the glycosyl hydrolase 43 family
AM458_RS05855	COG2211	Major facilitator Superfamily
AM458_RS05865	COG4580	involved in the transport of maltose and maltodextrins
AM458_RS05870	COG3272	Protein of unknown function (DUF1722)
AM458_RS05890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM458_RS05905	COG0300	oxidoreductase activity
AM458_RS05915	COG0789	Transcriptional regulator
AM458_RS05920	COG3040	lipid binding
AM458_RS05930	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM458_RS05935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM458_RS05940	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM458_RS05945	COG1538	Outer membrane efflux protein
AM458_RS05955	COG0745	RESPONSE REGULATOR receiver
AM458_RS05960	COG5002	protein histidine kinase activity
AM458_RS05975	COG2850	peptidyl-arginine hydroxylation
AM458_RS06010	COG0842	Transport permease protein
AM458_RS06015	COG0842	Transport permease protein
AM458_RS06015	COG1129	ABC transporter
AM458_RS06020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM458_RS06030	COG1879	ABC-type sugar transport system periplasmic component
AM458_RS06035	COG1129	ABC transporter
AM458_RS06040	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS06050	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM458_RS06055	COG0583	DNA-binding transcription factor activity
AM458_RS06065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM458_RS06070	COG5457	Domain of unknown function (DUF1127)
AM458_RS06080	COG1566	PFAM secretion protein HlyD family protein
AM458_RS06095	COG1924	4 iron, 4 sulfur cluster binding
AM458_RS06100	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AM458_RS06115	COG2733	membrane
AM458_RS06125	COG2207	Transcriptional regulator
AM458_RS06125	COG1917	Cupin 2, conserved barrel domain protein
AM458_RS06135	COG5464	transposase or invertase
AM458_RS06140	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS06150	COG0523	cobalamin synthesis protein
AM458_RS06155	COG2879	small protein
AM458_RS06160	COG1966	Carbon starvation protein
AM458_RS06175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM458_RS06180	COG2368	4-hydroxyphenylacetate
AM458_RS06200	COG3971	2-oxopent-4-enoate hydratase activity
AM458_RS06210	COG3384	dioxygenase
AM458_RS06215	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS06225	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM458_RS06235	COG1846	Transcriptional regulator
AM458_RS06265	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AM458_RS06280	COG3734	2-keto-3-deoxy-galactonokinase
AM458_RS06285	COG0800	Aldolase
AM458_RS06290	COG1737	Transcriptional regulator
AM458_RS06300	COG0456	acetyltransferase
AM458_RS06300	COG1214	PFAM Peptidase M22, glycoprotease
AM458_RS06305	COG2271	Major facilitator Superfamily
AM458_RS06310	COG1802	Transcriptional regulator
AM458_RS06315	COG1063	alcohol dehydrogenase
AM458_RS06325	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM458_RS06325	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AM458_RS06340	COG3715	PTS system
AM458_RS06345	COG3716	PTS system mannose fructose sorbose family IID component
AM458_RS06350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM458_RS06360	COG5464	transposase or invertase
AM458_RS06375	COG1484	DNA-dependent DNA replication
AM458_RS06390	COG2966	Psort location CytoplasmicMembrane, score
AM458_RS06410	COG2197	response regulator
AM458_RS06415	COG2197	response regulator
AM458_RS06420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM458_RS06425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS06425	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS06430	COG4114	ferric iron reductase
AM458_RS06435	COG3706	GGDEF domain
AM458_RS06465	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AM458_RS06470	COG0456	acetyltransferase
AM458_RS06475	COG1011	Hydrolase
AM458_RS06485	COG2823	Periplasmic or secreted lipoprotein
AM458_RS06495	COG4667	esterase of the alpha-beta hydrolase superfamily
AM458_RS06500	COG0084	hydrolase, TatD family'
AM458_RS06505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM458_RS06535	COG3726	membrane protein affecting hemolysin expression
AM458_RS06545	COG0560	Phosphoserine phosphatase
AM458_RS06550	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AM458_RS06560	COG0488	(ABC) transporter
AM458_RS06570	COG0741	lytic transglycosylase activity
AM458_RS06590	COG3708	Transcriptional regulator
AM458_RS06590	COG2207	Transcriptional regulator
AM458_RS06595	COG3045	CreA protein
AM458_RS06600	COG0745	RESPONSE REGULATOR receiver
AM458_RS06605	COG2205	protein histidine kinase activity
AM458_RS06610	COG4452	Inner membrane protein CreD
AM458_RS06615	COG0745	RESPONSE REGULATOR receiver
AM458_RS06630	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM458_RS06640	COG0460	homoserine dehydrogenase
AM458_RS06640	COG0527	aspartate kinase activity
AM458_RS06650	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM458_RS06665	COG1115	amino acid carrier protein
AM458_RS06670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM458_RS06675	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM458_RS06680	COG0477	Major facilitator Superfamily
AM458_RS06685	COG1584	GPR1 FUN34 yaaH family protein
AM458_RS06690	COG4735	regulation of single-species biofilm formation
AM458_RS06715	COG0583	DNA-binding transcription factor activity
AM458_RS06735	COG0196	riboflavin kinase activity
AM458_RS06750	COG1047	Peptidyl-prolyl cis-trans
AM458_RS06775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM458_RS06845	COG0505	Belongs to the CarA family
AM458_RS06900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM458_RS06910	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM458_RS06915	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM458_RS06930	COG3493	citrate carrier protein
AM458_RS06945	COG0564	pseudouridine synthase activity
AM458_RS06955	COG0417	DNA replication proofreading
AM458_RS06960	COG0235	Class ii aldolase
AM458_RS06980	COG0586	Pfam SNARE associated Golgi protein
AM458_RS06990	COG1178	ABC-type Fe3 transport system permease component
AM458_RS07010	COG2814	Major facilitator Superfamily
AM458_RS07015	COG2271	Major facilitator Superfamily
AM458_RS07020	COG0583	DNA-binding transcription factor activity
AM458_RS07030	COG0738	Major facilitator superfamily
AM458_RS07080	COG0028	Belongs to the TPP enzyme family
AM458_RS07090	COG1609	Transcriptional regulator
AM458_RS07115	COG0768	penicillin binding
AM458_RS07120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM458_RS07125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM458_RS07140	COG0772	Belongs to the SEDS family
AM458_RS07165	COG0849	cell division
AM458_RS07170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM458_RS07190	COG0494	nUDIX hydrolase
AM458_RS07215	COG1459	type II secretion system
AM458_RS07220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM458_RS07225	COG4969	Belongs to the N-Me-Phe pilin family
AM458_RS07235	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM458_RS07240	COG3725	Membrane protein required for beta-lactamase induction
AM458_RS07245	COG3940	Belongs to the glycosyl hydrolase 43 family
AM458_RS07250	COG2211	Major facilitator Superfamily
AM458_RS07255	COG1113	amino acid transport
AM458_RS07260	COG2186	Transcriptional regulator
AM458_RS07265	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM458_RS07270	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM458_RS07275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM458_RS07290	COG3064	Membrane
AM458_RS07350	COG2132	Multicopper oxidase
AM458_RS07355	COG4993	Dehydrogenase
AM458_RS07365	COG0288	reversible hydration of carbon dioxide
AM458_RS07370	COG1131	(ABC) transporter
AM458_RS07375	COG0842	Transport permease protein
AM458_RS07380	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS07385	COG0726	polysaccharide deacetylase
AM458_RS07405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM458_RS07410	COG0617	tRNA 3'-terminal CCA addition
AM458_RS07430	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM458_RS07435	COG1643	Atp-dependent helicase
AM458_RS07525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM458_RS07530	COG4774	siderophore transport
AM458_RS07535	COG1120	ATPase activity
AM458_RS07540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM458_RS07545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM458_RS07565	COG2860	membrane
AM458_RS07585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM458_RS07590	COG3835	regulator
AM458_RS07605	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AM458_RS07610	COG0024	Methionine aminopeptidase
AM458_RS07635	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM458_RS07650	COG0575	Belongs to the CDS family
AM458_RS07655	COG0750	zinc metalloprotease
AM458_RS07665	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AM458_RS07705	COG1982	Orn Lys Arg decarboxylase major
AM458_RS07710	COG0346	lactoylglutathione lyase activity
AM458_RS07720	COG4568	rho-dependent transcription termination
AM458_RS07735	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM458_RS07740	COG3015	lipoprotein NlpE involved in copper resistance
AM458_RS07745	COG0791	NLP P60 protein
AM458_RS07755	COG1720	tRNA m6t6A37 methyltransferase activity
AM458_RS07765	COG1464	Belongs to the NlpA lipoprotein family
AM458_RS07770	COG2011	ABC-type metal ion transport system permease component
AM458_RS07780	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM458_RS07820	COG0656	L-ascorbic acid biosynthetic process
AM458_RS07825	COG0583	DNA-binding transcription factor activity
AM458_RS07830	COG2814	Major facilitator Superfamily
AM458_RS07840	COG2226	methyltransferase
AM458_RS07845	COG0741	lytic transglycosylase activity
AM458_RS07845	COG1388	LysM domain
AM458_RS07855	COG2226	methyltransferase
AM458_RS07865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM458_RS07880	COG0583	DNA-binding transcription factor activity
AM458_RS07890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM458_RS07895	COG1960	acyl-CoA dehydrogenase activity
AM458_RS07905	COG0121	glutamine amidotransferase
AM458_RS07910	COG3034	peptidoglycan biosynthetic process
AM458_RS07930	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM458_RS07935	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM458_RS07950	COG2991	Protein conserved in bacteria
AM458_RS07965	COG0454	-acetyltransferase
AM458_RS07970	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM458_RS07990	COG1802	Transcriptional regulator
AM458_RS07995	COG1113	amino acid transport
AM458_RS08000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM458_RS08005	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS08010	COG0579	oxidoreductase
AM458_RS08030	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AM458_RS08035	COG0625	glutathione transferase activity
AM458_RS08040	COG3775	system Galactitol-specific IIC component
AM458_RS08045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM458_RS08050	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS08055	COG1070	Carbohydrate kinase
AM458_RS08080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM458_RS08085	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM458_RS08090	COG0022	dehydrogenase e1 component
AM458_RS08095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM458_RS08155	COG1192	Involved in chromosome partitioning
AM458_RS08160	COG0582	viral genome integration into host DNA
AM458_RS08185	COG0791	NLP P60 protein
AM458_RS08220	COG3639	organic phosphonate transmembrane transporter activity
AM458_RS08230	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM458_RS08255	COG3188	usher protein
AM458_RS08270	COG0765	amino acid transport
AM458_RS08275	COG0765	amino acid transport
AM458_RS08280	COG1126	abc transporter atp-binding protein
AM458_RS08285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM458_RS08320	COG4302	ethanolamine ammonia-lyase activity
AM458_RS08325	COG4303	Ethanolamine ammonia lyase large subunit
AM458_RS08335	COG0833	amino acid
AM458_RS08340	COG2040	homocysteine
AM458_RS08345	COG4521	taurine ABC transporter
AM458_RS08350	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AM458_RS08355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM458_RS08360	COG2175	clavaminate synthase activity
AM458_RS08370	COG0113	porphobilinogen synthase activity
AM458_RS08375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM458_RS08380	COG1335	isochorismatase
AM458_RS08385	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM458_RS08425	COG1785	Belongs to the alkaline phosphatase family
AM458_RS08435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM458_RS08445	COG3416	Protein conserved in bacteria
AM458_RS08450	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM458_RS08460	COG4126	flavin adenine dinucleotide binding
AM458_RS08475	COG1940	carbohydrate kinase activity
AM458_RS08480	COG0419	ATPase involved in DNA repair
AM458_RS08485	COG0420	3'-5' exonuclease activity
AM458_RS08510	COG0366	Alpha amylase catalytic
AM458_RS08515	COG0583	DNA-binding transcription factor activity
AM458_RS08520	COG1335	isochorismatase
AM458_RS08530	COG1228	amidohydrolase
AM458_RS08540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM458_RS08555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS08560	COG0450	alkyl hydroperoxide reductase
AM458_RS08580	COG1862	Preprotein translocase
AM458_RS08585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM458_RS08590	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM458_RS08610	COG4238	major outer membrane lipoprotein
AM458_RS08620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM458_RS08620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM458_RS08640	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM458_RS08645	COG0667	Aldo Keto reductase
AM458_RS08655	COG0142	geranyltranstransferase activity
AM458_RS08675	COG0693	protein deglycase activity
AM458_RS08680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM458_RS08690	COG2814	Major facilitator Superfamily
AM458_RS08695	COG0673	inositol 2-dehydrogenase activity
AM458_RS08710	COG1053	succinate dehydrogenase
AM458_RS08720	COG1053	succinate dehydrogenase
AM458_RS08725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM458_RS08730	COG1414	Transcriptional regulator
AM458_RS08745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM458_RS08750	COG1845	cytochrome c oxidase, subunit III
AM458_RS08755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM458_RS08760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM458_RS08765	COG2223	nitrite transmembrane transporter activity
AM458_RS08770	COG3056	Lipoprotein
AM458_RS08775	COG0271	Belongs to the BolA IbaG family
AM458_RS08805	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM458_RS08810	COG0776	regulation of translation
AM458_RS08815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM458_RS08820	COG1555	photosystem II stabilization
AM458_RS08825	COG0824	Thioesterase
AM458_RS08835	COG4533	DNA binding
AM458_RS08850	COG1522	sequence-specific DNA binding
AM458_RS08855	COG1132	(ABC) transporter
AM458_RS08860	COG1132	(ABC) transporter
AM458_RS08865	COG0347	Belongs to the P(II) protein family
AM458_RS08870	COG0004	ammonium transporteR
AM458_RS08875	COG1946	Acyl-CoA thioesterase
AM458_RS08880	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AM458_RS08885	COG3695	enzyme binding
AM458_RS08915	COG2364	Membrane
AM458_RS08930	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM458_RS08940	COG2182	Extracellular solute-binding protein
AM458_RS08945	COG1175	transmembrane transport
AM458_RS08950	COG3833	ABC-type maltose transport systems, permease component
AM458_RS08955	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AM458_RS08960	COG1874	Beta-galactosidase
AM458_RS09005	COG0110	maltose O-acetyltransferase activity
AM458_RS09020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM458_RS09025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM458_RS09030	COG1309	transcriptional regulator
AM458_RS09035	COG1196	nuclear chromosome segregation
AM458_RS09035	COG3264	Mechanosensitive ion channel
AM458_RS09040	COG5464	transposase or invertase
AM458_RS09050	COG3923	Primosomal replication protein n
AM458_RS09055	COG2832	Protein of unknown function (DUF454)
AM458_RS09100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM458_RS09105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM458_RS09105	COG4651	solute:proton antiporter activity
AM458_RS09110	COG2223	nitrite transmembrane transporter activity
AM458_RS09120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM458_RS09125	COG3735	TraB family
AM458_RS09140	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM458_RS09145	COG0330	HflC and HflK could
AM458_RS09150	COG4619	ABC transporter
AM458_RS09155	COG0390	transport system, permease component
AM458_RS09165	COG3118	belongs to the thioredoxin family
AM458_RS09170	COG0300	oxidoreductase activity
AM458_RS09175	COG2755	lipolytic protein G-D-S-L family
AM458_RS09180	COG4181	ATPase activity
AM458_RS09185	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM458_RS09200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM458_RS09205	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM458_RS09225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM458_RS09235	COG2501	S4 domain
AM458_RS09255	COG0582	viral genome integration into host DNA
AM458_RS09335	COG0305	Participates in initiation and elongation during chromosome replication
AM458_RS09405	COG3772	lysozyme
AM458_RS09590	COG3344	reverse transcriptase
AM458_RS09645	COG3539	Fimbrial protein
AM458_RS09650	COG3121	Chaperone
AM458_RS09655	COG3188	usher protein
AM458_RS09670	COG1560	Kdo2-lipid A biosynthetic process
AM458_RS09680	COG3710	Transcriptional regulator
AM458_RS09685	COG0531	amino acid
AM458_RS09690	COG1982	Orn Lys Arg decarboxylase major
AM458_RS09695	COG3104	oligopeptide transport
AM458_RS09725	COG0673	inositol 2-dehydrogenase activity
AM458_RS09740	COG1129	ABC transporter
AM458_RS09745	COG4211	Belongs to the binding-protein-dependent transport system permease family
AM458_RS09790	COG1566	PFAM secretion protein HlyD family protein
AM458_RS09795	COG1120	ATPase activity
AM458_RS09800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM458_RS09820	COG1473	amidohydrolase
AM458_RS09825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM458_RS09830	COG0667	Aldo Keto reductase
AM458_RS09840	COG4608	Belongs to the ABC transporter superfamily
AM458_RS09845	COG0444	Belongs to the ABC transporter superfamily
AM458_RS09850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM458_RS09855	COG0601	transmembrane transport
AM458_RS09860	COG0747	negative chemotaxis
AM458_RS09890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM458_RS09900	COG0668	transmembrane transport
AM458_RS09905	COG0583	DNA-binding transcription factor activity
AM458_RS09915	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS09920	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS09925	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS09930	COG1129	ABC transporter
AM458_RS09940	COG1879	ABC-type sugar transport system periplasmic component
AM458_RS09945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM458_RS09950	COG2390	Transcriptional regulator
AM458_RS09960	COG3959	Transketolase, thiamine diphosphate binding domain
AM458_RS09965	COG3958	Transketolase
AM458_RS09970	COG2977	Belongs to the P-Pant transferase superfamily
AM458_RS09975	COG4771	TonB-dependent receptor
AM458_RS09980	COG2382	esterase
AM458_RS09985	COG3251	PFAM MbtH domain protein
AM458_RS09990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM458_RS09990	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM458_RS09995	COG1120	ATPase activity
AM458_RS10000	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM458_RS10005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM458_RS10015	COG4592	Periplasmic binding protein
AM458_RS10020	COG1169	isochorismate synthase
AM458_RS10025	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM458_RS10030	COG3433	isochorismatase activity
AM458_RS10030	COG1535	isochorismatase
AM458_RS10035	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS10045	COG1966	Carbon starvation protein
AM458_RS10050	COG2879	small protein
AM458_RS10065	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS10070	COG0371	Dehydrogenase
AM458_RS10075	COG1129	ABC transporter
AM458_RS10080	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS10110	COG2271	Major facilitator Superfamily
AM458_RS10115	COG0483	inositol monophosphate 1-phosphatase activity
AM458_RS10125	COG0402	S-adenosylhomocysteine deaminase activity
AM458_RS10135	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM458_RS10150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM458_RS10160	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS10165	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS10170	COG1129	ABC transporter
AM458_RS10195	COG0436	Aminotransferase
AM458_RS10200	COG1475	DNA binding
AM458_RS10205	COG3969	phosphoadenosine phosphosulfate
AM458_RS10210	COG0583	DNA-binding transcription factor activity
AM458_RS10215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM458_RS10235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM458_RS10240	COG3719	Belongs to the RNase T2 family
AM458_RS10245	COG3069	C4-dicarboxylate transmembrane transporter activity
AM458_RS10270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM458_RS10285	COG0583	DNA-binding transcription factor activity
AM458_RS10300	COG1686	Belongs to the peptidase S11 family
AM458_RS10305	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM458_RS10310	COG0772	Belongs to the SEDS family
AM458_RS10315	COG0768	penicillin binding
AM458_RS10325	COG0799	negative regulation of ribosome biogenesis
AM458_RS10345	COG1466	dna polymerase III delta subunit
AM458_RS10360	COG2888	peptidyl-tyrosine sulfation
AM458_RS10375	COG1126	abc transporter atp-binding protein
AM458_RS10380	COG0765	amino acid transport
AM458_RS10385	COG0765	amino acid transport
AM458_RS10400	COG4535	Mg2 and Co2 transporter CorC
AM458_RS10410	COG1702	phosphate starvation-inducible protein PhoH
AM458_RS10420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM458_RS10465	COG0367	asparagine synthase
AM458_RS10470	COG0647	UMP catabolic process
AM458_RS10475	COG1846	Transcriptional regulator
AM458_RS10475	COG1940	carbohydrate kinase activity
AM458_RS10480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM458_RS10525	COG0735	belongs to the Fur family
AM458_RS10540	COG0596	Alpha beta hydrolase
AM458_RS10550	COG0033	Phosphoglucomutase
AM458_RS10560	COG0745	RESPONSE REGULATOR receiver
AM458_RS10565	COG2205	protein histidine kinase activity
AM458_RS10595	COG0415	Belongs to the DNA photolyase family
AM458_RS10610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM458_RS10615	COG1984	allophanate hydrolase subunit 2
AM458_RS10660	COG2009	succinate dehydrogenase
AM458_RS10665	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM458_RS10670	COG1053	succinate dehydrogenase
AM458_RS10675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM458_RS10680	COG0567	Dehydrogenase, E1 component
AM458_RS10685	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM458_RS10700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM458_RS10710	COG1271	oxidase subunit
AM458_RS10715	COG1294	oxidase, subunit
AM458_RS10720	COG4890	Cyd operon protein YbgT
AM458_RS10725	COG3790	cyd operon protein YbgE
AM458_RS10730	COG0824	Thioesterase
AM458_RS10735	COG0811	peptide transport
AM458_RS10740	COG0848	biopolymer transport protein
AM458_RS10745	COG3064	Membrane
AM458_RS10755	COG2885	chlorophyll binding
AM458_RS10760	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM458_RS10805	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM458_RS10810	COG3201	nicotinamide mononucleotide transporter
AM458_RS10825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM458_RS10835	COG2017	converts alpha-aldose to the beta-anomer
AM458_RS10845	COG1085	galactose-1-phosphate uridylyltransferase
AM458_RS10855	COG1119	ATPase activity
AM458_RS10860	COG3585	molybdate ion transport
AM458_RS10860	COG2005	Transcriptional regulator
AM458_RS10870	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM458_RS10875	COG4149	molybdate abc transporter
AM458_RS10880	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM458_RS10885	COG0561	phosphatase activity
AM458_RS10910	COG2200	EAL domain
AM458_RS10915	COG0789	Transcriptional regulator
AM458_RS10945	COG4677	pectinesterase activity
AM458_RS10985	COG1881	PFAM PEBP family protein
AM458_RS10990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM458_RS11005	COG2226	methyltransferase
AM458_RS11040	COG0642	Histidine kinase
AM458_RS11045	COG0745	RESPONSE REGULATOR receiver
AM458_RS11070	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM458_RS11080	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM458_RS11085	COG0314	molybdopterin synthase activity
AM458_RS11090	COG0670	Belongs to the BI1 family
AM458_RS11105	COG0392	lysyltransferase activity
AM458_RS11110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM458_RS11115	COG3568	Endonuclease Exonuclease Phosphatase
AM458_RS11130	COG0842	Transport permease protein
AM458_RS11135	COG0842	Transport permease protein
AM458_RS11140	COG1131	(ABC) transporter
AM458_RS11145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM458_RS11150	COG1309	transcriptional regulator
AM458_RS11155	COG0583	DNA-binding transcription factor activity
AM458_RS11160	COG2271	Major facilitator Superfamily
AM458_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS11170	COG3959	Transketolase, thiamine diphosphate binding domain
AM458_RS11175	COG3958	Transketolase
AM458_RS11180	COG0513	Belongs to the DEAD box helicase family
AM458_RS11185	COG1199	ATP-dependent helicase activity
AM458_RS11190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM458_RS11200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM458_RS11210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM458_RS11220	COG0668	transmembrane transport
AM458_RS11225	COG1126	abc transporter atp-binding protein
AM458_RS11230	COG0765	amino acid transport
AM458_RS11235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM458_RS11250	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM458_RS11255	COG2194	sulfuric ester hydrolase activity
AM458_RS11265	COG1321	iron dependent repressor
AM458_RS11270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM458_RS11275	COG2723	6-phospho-beta-galactosidase activity
AM458_RS11280	COG2188	Transcriptional regulator
AM458_RS11285	COG1376	ErfK ybiS ycfS ynhG family protein
AM458_RS11290	COG2365	Tyrosine phosphatase family
AM458_RS11295	COG0488	(ABC) transporter
AM458_RS11310	COG2271	Major facilitator Superfamily
AM458_RS11315	COG1609	Transcriptional regulator
AM458_RS11325	COG0561	phosphatase activity
AM458_RS11330	COG1882	Formate acetyltransferase
AM458_RS11335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM458_RS11340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM458_RS11345	COG0303	'Molybdopterin
AM458_RS11360	COG0747	negative chemotaxis
AM458_RS11385	COG2223	nitrite transmembrane transporter activity
AM458_RS11395	COG2133	pyrroloquinoline quinone binding
AM458_RS11400	COG0625	glutathione transferase activity
AM458_RS11405	COG1686	Belongs to the peptidase S11 family
AM458_RS11410	COG1349	DNA-binding transcription factor activity
AM458_RS11415	COG0671	phosphoesterase, PA-phosphatase related
AM458_RS11425	COG2814	Major facilitator Superfamily
AM458_RS11430	COG0561	phosphatase activity
AM458_RS11435	COG0738	Major facilitator superfamily
AM458_RS11440	COG3226	Transcriptional regulator
AM458_RS11445	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM458_RS11455	COG3344	reverse transcriptase
AM458_RS11480	COG4695	Portal protein
AM458_RS11665	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM458_RS11670	COG3842	ATPase activity
AM458_RS11675	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM458_RS11680	COG1177	transmembrane transport
AM458_RS11695	COG0745	RESPONSE REGULATOR receiver
AM458_RS11700	COG5002	protein histidine kinase activity
AM458_RS11705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM458_RS11710	COG4160	amino acid transport
AM458_RS11715	COG4215	(ABC) transporter
AM458_RS11720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM458_RS11725	COG1126	abc transporter atp-binding protein
AM458_RS11740	COG2203	Gaf domain
AM458_RS11740	COG3706	GGDEF domain
AM458_RS11740	COG4251	negative regulation of phosphorylation
AM458_RS11740	COG5001	Diguanylate cyclase
AM458_RS11745	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM458_RS11750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM458_RS11755	COG0702	epimerase
AM458_RS11760	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM458_RS11765	COG0028	Belongs to the TPP enzyme family
AM458_RS11780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM458_RS11790	COG2431	L-lysine efflux transmembrane transporter activity
AM458_RS11810	COG3593	DNA synthesis involved in DNA repair
AM458_RS11815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM458_RS11830	COG1278	Cold shock
AM458_RS11840	COG0542	response to heat
AM458_RS11855	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM458_RS11860	COG4988	ABC transporter
AM458_RS11865	COG0492	ferredoxin-NADP+ reductase activity
AM458_RS11875	COG1178	ABC-type Fe3 transport system permease component
AM458_RS11875	COG1674	ftsk spoiiie
AM458_RS11885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM458_RS11895	COG0243	molybdopterin cofactor binding
AM458_RS11900	COG0437	4 iron, 4 sulfur cluster binding
AM458_RS11905	COG3302	dmso reductase anchor subunit
AM458_RS11915	COG0477	Major facilitator Superfamily
AM458_RS11920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM458_RS11925	COG1882	Formate acetyltransferase
AM458_RS11930	COG2116	formate transmembrane transporter activity
AM458_RS11935	COG1944	ATP diphosphatase activity
AM458_RS11940	COG2323	membrane
AM458_RS11960	COG0539	negative regulation of cytoplasmic translation
AM458_RS11970	COG2333	competence protein COMEC
AM458_RS11970	COG0658	competence protein
AM458_RS11985	COG3214	Protein conserved in bacteria
AM458_RS12000	COG3173	Aminoglycoside phosphotransferase
AM458_RS12005	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM458_RS12010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM458_RS12020	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AM458_RS12030	COG2989	Protein conserved in bacteria
AM458_RS12040	COG3108	Peptidase M15
AM458_RS12045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM458_RS12050	COG1448	Aminotransferase
AM458_RS12065	COG1522	sequence-specific DNA binding
AM458_RS12075	COG0814	amino acid
AM458_RS12085	COG1473	amidohydrolase
AM458_RS12100	COG0308	aminopeptidase N
AM458_RS12110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM458_RS12115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM458_RS12120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM458_RS12125	COG0431	NADPH-dependent FMN reductase
AM458_RS12140	COG3217	Mosc domain protein beta barrel domain protein
AM458_RS12140	COG0633	Ferredoxin
AM458_RS12150	COG0488	(ABC) transporter
AM458_RS12155	COG2995	paraquat-inducible protein a
AM458_RS12160	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM458_RS12160	COG3008	intermembrane lipid transfer
AM458_RS12165	COG3009	Protein conserved in bacteria
AM458_RS12175	COG3130	regulation of translation
AM458_RS12185	COG1067	ATP-dependent peptidase activity
AM458_RS12210	COG3070	regulator of competence-specific genes
AM458_RS12215	COG1289	transmembrane transporter activity
AM458_RS12220	COG3304	Inner membrane component domain
AM458_RS12225	COG0210	DNA helicase
AM458_RS12235	COG1832	CoA-binding protein
AM458_RS12250	COG1881	PFAM PEBP family protein
AM458_RS12255	COG2207	Transcriptional regulator
AM458_RS12270	COG0670	Belongs to the BI1 family
AM458_RS12285	COG2200	EAL domain
AM458_RS12290	COG2200	EAL domain
AM458_RS12300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM458_RS12305	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS12310	COG4638	Rieske (2fe-2S)
AM458_RS12315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM458_RS12325	COG0473	3-isopropylmalate dehydrogenase activity
AM458_RS12330	COG0583	DNA-binding transcription factor activity
AM458_RS12335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM458_RS12340	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS12345	COG1917	Cupin 2, conserved barrel domain protein
AM458_RS12345	COG1396	sequence-specific DNA binding
AM458_RS12350	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM458_RS12355	COG0174	glutamine synthetase
AM458_RS12365	COG0531	amino acid
AM458_RS12380	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS12405	COG3729	General stress protein
AM458_RS12415	COG2233	PERMEase
AM458_RS12450	COG1309	transcriptional regulator
AM458_RS12470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM458_RS12480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM458_RS12500	COG1702	phosphate starvation-inducible protein PhoH
AM458_RS12505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM458_RS12520	COG1335	isochorismatase
AM458_RS12530	COG0583	DNA-binding transcription factor activity
AM458_RS12560	COG3381	protein complex oligomerization
AM458_RS12600	COG5645	(Lipo)protein
AM458_RS12620	COG1560	Kdo2-lipid A biosynthetic process
AM458_RS12670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM458_RS12690	COG2814	Major facilitator Superfamily
AM458_RS12695	COG0583	DNA-binding transcription factor activity
AM458_RS12700	COG1530	ribonuclease E activity
AM458_RS12720	COG1399	metal-binding, possibly nucleic acid-binding protein
AM458_RS12740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM458_RS12755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM458_RS12760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM458_RS12765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM458_RS12775	COG0470	DNA polymerase III
AM458_RS12780	COG0084	hydrolase, TatD family'
AM458_RS12790	COG0537	adenosine 5'-monophosphoramidase activity
AM458_RS12795	COG5633	Lipoprotein
AM458_RS12820	COG1252	NADH dehydrogenase
AM458_RS12825	COG3134	Outer membrane lipoprotein
AM458_RS12835	COG1309	transcriptional regulator
AM458_RS12845	COG1376	ErfK ybiS ycfS ynhG family protein
AM458_RS12845	COG1388	LysM domain
AM458_RS12850	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM458_RS12855	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM458_RS12865	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM458_RS12875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM458_RS12885	COG0318	PFAM AMP-dependent synthetase and ligase
AM458_RS12900	COG1177	transmembrane transport
AM458_RS12920	COG2850	peptidyl-arginine hydroxylation
AM458_RS12925	COG2205	protein histidine kinase activity
AM458_RS12945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM458_RS12965	COG1187	pseudouridine synthase activity
AM458_RS12970	COG0538	isocitrate dehydrogenase activity
AM458_RS12975	COG0640	Transcriptional regulator
AM458_RS12990	COG3813	Protein conserved in bacteria
AM458_RS12995	COG1063	alcohol dehydrogenase
AM458_RS13000	COG3729	General stress protein
AM458_RS13005	COG3685	Protein conserved in bacteria
AM458_RS13010	COG3685	Protein conserved in bacteria
AM458_RS13015	COG3546	catalase activity
AM458_RS13020	COG1271	oxidase subunit
AM458_RS13025	COG1294	oxidase, subunit
AM458_RS13050	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM458_RS13055	COG0583	DNA-binding transcription factor activity
AM458_RS13060	COG3706	GGDEF domain
AM458_RS13065	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AM458_RS13080	COG1560	Kdo2-lipid A biosynthetic process
AM458_RS13090	COG3182	Iron-regulated membrane protein
AM458_RS13110	COG2199	diguanylate cyclase activity
AM458_RS13110	COG2203	Gaf domain
AM458_RS13115	COG3042	response to heat
AM458_RS13120	COG3189	MarR family transcriptional regulator
AM458_RS13125	COG1683	Conserved Protein
AM458_RS13130	COG0504	CTP synthase activity
AM458_RS13135	COG2807	transmembrane transport
AM458_RS13140	COG2207	Transcriptional regulator
AM458_RS13150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM458_RS13155	COG0859	PFAM glycosyl transferase family 9
AM458_RS13170	COG3344	reverse transcriptase
AM458_RS13175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM458_RS13180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM458_RS13185	COG0583	DNA-binding transcription factor activity
AM458_RS13190	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS13210	COG0386	Belongs to the glutathione peroxidase family
AM458_RS13225	COG2766	serine protein kinase
AM458_RS13230	COG3713	MltA-interacting MipA family protein
AM458_RS13235	COG0656	L-ascorbic acid biosynthetic process
AM458_RS13255	COG3139	Protein of unknown function (DUF1315)
AM458_RS13270	COG1063	alcohol dehydrogenase
AM458_RS13275	COG2271	Major facilitator Superfamily
AM458_RS13280	COG1063	alcohol dehydrogenase
AM458_RS13285	COG0191	fructose-bisphosphate aldolase activity
AM458_RS13290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM458_RS13295	COG0667	Aldo Keto reductase
AM458_RS13300	COG1349	DNA-binding transcription factor activity
AM458_RS13305	COG2814	Major facilitator Superfamily
AM458_RS13310	COG1335	isochorismatase
AM458_RS13315	COG0252	asparaginase activity
AM458_RS13320	COG0616	signal peptide processing
AM458_RS13325	COG0778	Nitroreductase
AM458_RS13345	COG0709	Synthesizes selenophosphate from selenide and ATP
AM458_RS13350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM458_RS13355	COG0604	alcohol dehydrogenase
AM458_RS13355	COG3321	synthase
AM458_RS13355	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS13360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM458_RS13365	COG0494	nUDIX hydrolase
AM458_RS13370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM458_RS13375	COG2897	thiosulfate sulfurtransferase activity
AM458_RS13380	COG4136	ATPase activity
AM458_RS13385	COG4135	transport system, permease component
AM458_RS13390	COG4134	Bacterial extracellular solute-binding protein
AM458_RS13395	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM458_RS13400	COG0398	Pfam SNARE associated Golgi protein
AM458_RS13405	COG0398	Pfam SNARE associated Golgi protein
AM458_RS13410	COG0708	Exodeoxyribonuclease III
AM458_RS13420	COG3138	arginine N-succinyltransferase
AM458_RS13430	COG3724	N-succinylarginine dihydrolase activity
AM458_RS13440	COG3678	ATP-independent chaperone mediated protein folding
AM458_RS13445	COG0322	excinuclease ABC activity
AM458_RS13455	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM458_RS13460	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS13465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS13470	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM458_RS13475	COG1917	Cupin 2, conserved barrel domain protein
AM458_RS13475	COG2169	Transcriptional regulator
AM458_RS13480	COG1486	melibiose metabolic process
AM458_RS13490	COG0753	catalase activity
AM458_RS13500	COG1823	symporter activity
AM458_RS13505	COG1988	membrane-bound metal-dependent
AM458_RS13510	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS13515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM458_RS13545	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM458_RS13550	COG3047	cAMP biosynthetic process
AM458_RS13560	COG4774	siderophore transport
AM458_RS13615	COG0135	phosphoribosylanthranilate isomerase activity
AM458_RS13615	COG0134	indole-3-glycerol-phosphate synthase activity
AM458_RS13620	COG0512	Glutamine amidotransferase of anthranilate synthase
AM458_RS13620	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM458_RS13625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM458_RS13635	COG0009	L-threonylcarbamoyladenylate synthase
AM458_RS13645	COG0583	DNA-binding transcription factor activity
AM458_RS13655	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM458_RS13660	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS13670	COG0616	signal peptide processing
AM458_RS13705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM458_RS13715	COG0671	phosphoesterase, PA-phosphatase related
AM458_RS13720	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM458_RS13725	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM458_RS13735	COG0023	Translation Initiation Factor
AM458_RS13745	COG1349	DNA-binding transcription factor activity
AM458_RS13760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM458_RS13760	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM458_RS13765	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM458_RS13775	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM458_RS13790	COG4171	peptide transport system, permease
AM458_RS13805	COG0702	epimerase
AM458_RS13820	COG1473	amidohydrolase
AM458_RS13830	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM458_RS13835	COG1842	Phage shock protein A
AM458_RS13845	COG1983	PspC domain protein
AM458_RS13855	COG3106	COG3106 Predicted ATPase
AM458_RS13865	COG0583	DNA-binding transcription factor activity
AM458_RS13870	COG1486	melibiose metabolic process
AM458_RS13880	COG3180	Ammonia monooxygenase
AM458_RS13885	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM458_RS13890	COG4948	Mandelate Racemase Muconate Lactonizing
AM458_RS13895	COG2866	Carboxypeptidase
AM458_RS13900	COG4166	transmembrane transport
AM458_RS13930	COG0656	L-ascorbic acid biosynthetic process
AM458_RS13950	COG0583	DNA-binding transcription factor activity
AM458_RS13955	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS13960	COG1078	dGTPase activity
AM458_RS13965	COG0693	protein deglycase activity
AM458_RS13970	COG0582	viral genome integration into host DNA
AM458_RS14070	COG0484	heat shock protein binding
AM458_RS14080	COG3772	lysozyme
AM458_RS14100	COG1783	phage Terminase large subunit
AM458_RS14105	COG3567	Phage-associated protein, HI1409 family
AM458_RS14175	COG0741	lytic transglycosylase activity
AM458_RS14175	COG0739	heme binding
AM458_RS14175	COG1196	nuclear chromosome segregation
AM458_RS14265	COG3344	reverse transcriptase
AM458_RS14305	COG2885	chlorophyll binding
AM458_RS14405	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS14410	COG1309	transcriptional regulator
AM458_RS14415	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS14435	COG0583	DNA-binding transcription factor activity
AM458_RS14460	COG0604	alcohol dehydrogenase
AM458_RS14465	COG0436	Aminotransferase
AM458_RS14480	COG2011	ABC-type metal ion transport system permease component
AM458_RS14485	COG1448	Aminotransferase
AM458_RS14495	COG1522	sequence-specific DNA binding
AM458_RS14500	COG1113	amino acid transport
AM458_RS14515	COG0673	inositol 2-dehydrogenase activity
AM458_RS14520	COG1349	DNA-binding transcription factor activity
AM458_RS14540	COG0513	Belongs to the DEAD box helicase family
AM458_RS14550	COG0589	response to stress
AM458_RS14560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM458_RS14565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM458_RS14565	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM458_RS14565	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM458_RS14565	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM458_RS14575	COG3042	response to heat
AM458_RS14580	COG3187	Heat shock protein
AM458_RS14585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM458_RS14590	COG0586	Pfam SNARE associated Golgi protein
AM458_RS14595	COG2911	Protein conserved in bacteria
AM458_RS14605	COG3784	Protein of unknown function (DUF1318)
AM458_RS14610	COG2207	Transcriptional regulator
AM458_RS14615	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS14645	COG2030	dehydratase
AM458_RS14645	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS14650	COG3396	Phenylacetate-CoA oxygenase
AM458_RS14655	COG3460	Phenylacetate-CoA oxygenase
AM458_RS14660	COG3396	Phenylacetate-CoA oxygenase
AM458_RS14665	COG2151	metal-sulfur cluster biosynthetic enzyme
AM458_RS14670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM458_RS14675	COG1024	Enoyl-CoA hydratase
AM458_RS14680	COG1024	Enoyl-CoA hydratase
AM458_RS14685	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM458_RS14690	COG2050	protein possibly involved in aromatic compounds catabolism
AM458_RS14695	COG0183	Belongs to the thiolase family
AM458_RS14700	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM458_RS14705	COG3327	negative regulation of DNA-templated transcription, initiation
AM458_RS14710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM458_RS14725	COG1643	Atp-dependent helicase
AM458_RS14730	COG4122	O-methyltransferase activity
AM458_RS14755	COG0583	DNA-binding transcription factor activity
AM458_RS14760	COG0667	Aldo Keto reductase
AM458_RS14765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM458_RS14770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM458_RS14775	COG3138	arginine N-succinyltransferase
AM458_RS14780	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS14785	COG3724	N-succinylarginine dihydrolase activity
AM458_RS14790	COG2988	succinylglutamate desuccinylase activity
AM458_RS14795	COG1113	amino acid transport
AM458_RS14800	COG0477	Major facilitator Superfamily
AM458_RS14805	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM458_RS14810	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS14815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM458_RS14820	COG0401	homolog of Blt101
AM458_RS14825	COG5562	phage envelope protein
AM458_RS14830	COG0425	Belongs to the sulfur carrier protein TusA family
AM458_RS14835	COG2391	methyltransferase activity
AM458_RS14860	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM458_RS14865	COG1263	PTS System
AM458_RS14865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM458_RS14870	COG1609	Transcriptional regulator
AM458_RS14875	COG5339	Protein conserved in bacteria
AM458_RS14880	COG1482	cell wall glycoprotein biosynthetic process
AM458_RS14885	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM458_RS14885	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM458_RS14890	COG0114	fumarate hydratase activity
AM458_RS14900	COG2205	protein histidine kinase activity
AM458_RS14910	COG0745	RESPONSE REGULATOR receiver
AM458_RS14915	COG3136	membrane protein required for alginate biosynthesis
AM458_RS14925	COG0531	amino acid
AM458_RS14945	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM458_RS14950	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM458_RS14965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM458_RS14980	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM458_RS14985	COG1473	amidohydrolase
AM458_RS14995	COG0583	DNA-binding transcription factor activity
AM458_RS15000	COG2840	Smr protein MutS2
AM458_RS15005	COG1414	Transcriptional regulator
AM458_RS15015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM458_RS15020	COG0183	Belongs to the thiolase family
AM458_RS15030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM458_RS15035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM458_RS15055	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM458_RS15055	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM458_RS15080	COG4565	transcriptional regulatory protein
AM458_RS15085	COG3290	protein histidine kinase activity
AM458_RS15110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM458_RS15120	COG0679	Auxin Efflux Carrier
AM458_RS15150	COG0628	permease
AM458_RS15170	COG3591	Belongs to the peptidase S1B family
AM458_RS15180	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AM458_RS15185	COG2814	Major facilitator Superfamily
AM458_RS15190	COG0583	DNA-binding transcription factor activity
AM458_RS15195	COG1940	carbohydrate kinase activity
AM458_RS15200	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM458_RS15215	COG3302	dmso reductase anchor subunit
AM458_RS15220	COG0437	4 iron, 4 sulfur cluster binding
AM458_RS15225	COG0243	molybdopterin cofactor binding
AM458_RS15240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM458_RS15255	COG2271	Major facilitator Superfamily
AM458_RS15260	COG0246	Mannitol dehydrogenase
AM458_RS15265	COG0589	response to stress
AM458_RS15270	COG1802	Transcriptional regulator
AM458_RS15275	COG4221	oxidoreductase activity
AM458_RS15290	COG2207	Transcriptional regulator
AM458_RS15295	COG2135	peptidase activity
AM458_RS15300	COG2197	response regulator
AM458_RS15310	COG0071	Belongs to the small heat shock protein (HSP20) family
AM458_RS15315	COG1546	Belongs to the CinA family
AM458_RS15320	COG2200	EAL domain
AM458_RS15335	COG3708	Transcriptional regulator
AM458_RS15335	COG2207	Transcriptional regulator
AM458_RS15340	COG2610	gluconate transmembrane transporter activity
AM458_RS15345	COG3622	Belongs to the hyi family
AM458_RS15350	COG0235	Class ii aldolase
AM458_RS15355	COG3395	kinase activity
AM458_RS15360	COG2084	Dehydrogenase
AM458_RS15365	COG1349	DNA-binding transcription factor activity
AM458_RS15380	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM458_RS15385	COG2223	nitrite transmembrane transporter activity
AM458_RS15420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM458_RS15425	COG0683	leucine binding
AM458_RS15440	COG1129	ABC transporter
AM458_RS15445	COG0410	ABC transporter
AM458_RS15455	COG2814	Major facilitator Superfamily
AM458_RS15460	COG0697	spore germination
AM458_RS15470	COG4977	sequence-specific DNA binding
AM458_RS15495	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS15500	COG2731	YhcH YjgK YiaL family protein
AM458_RS15515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM458_RS15525	COG3395	kinase activity
AM458_RS15530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM458_RS15535	COG1349	DNA-binding transcription factor activity
AM458_RS15540	COG0039	L-malate dehydrogenase activity
AM458_RS15550	COG0583	DNA-binding transcription factor activity
AM458_RS15555	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS15570	COG2199	diguanylate cyclase activity
AM458_RS15650	COG0477	Major facilitator Superfamily
AM458_RS15660	COG2070	2-Nitropropane dioxygenase
AM458_RS15665	COG2011	ABC-type metal ion transport system permease component
AM458_RS15685	COG4628	conserved protein (DUF2132)
AM458_RS15700	COG2207	Transcriptional regulator
AM458_RS15730	COG2233	PERMEase
AM458_RS15735	COG3648	Uricase
AM458_RS15735	COG3195	allantoin biosynthetic process
AM458_RS15740	COG2351	hydroxyisourate hydrolase activity
AM458_RS15745	COG1396	sequence-specific DNA binding
AM458_RS15750	COG3550	peptidyl-serine autophosphorylation
AM458_RS15755	COG1649	PFAM Uncharacterised BCR, COG1649
AM458_RS15765	COG3188	usher protein
AM458_RS15800	COG3300	MHYT domain
AM458_RS15800	COG5001	Diguanylate cyclase
AM458_RS15805	COG2819	hydrolase of the alpha beta superfamily
AM458_RS15815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS15815	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS15820	COG2814	Major facilitator Superfamily
AM458_RS15835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM458_RS15835	COG1263	PTS System
AM458_RS15840	COG2186	Transcriptional regulator
AM458_RS15860	COG3835	regulator
AM458_RS15865	COG1929	Belongs to the glycerate kinase type-1 family
AM458_RS15910	COG0738	Major facilitator superfamily
AM458_RS15915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM458_RS15920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM458_RS15925	COG1349	DNA-binding transcription factor activity
AM458_RS15940	COG1349	DNA-binding transcription factor activity
AM458_RS15945	COG4977	sequence-specific DNA binding
AM458_RS15965	COG4977	sequence-specific DNA binding
AM458_RS15975	COG2801	Transposase and inactivated derivatives
AM458_RS15985	COG2801	Transposase and inactivated derivatives
AM458_RS16020	COG0667	Aldo Keto reductase
AM458_RS16030	COG0667	Aldo Keto reductase
AM458_RS16035	COG0667	Aldo Keto reductase
AM458_RS16045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM458_RS16045	COG0456	acetyltransferase
AM458_RS16075	COG0426	domain, Protein
AM458_RS16075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM458_RS16090	COG1652	LysM domain
AM458_RS16120	COG1609	Transcriptional regulator
AM458_RS16130	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS16145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM458_RS16155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM458_RS16160	COG0583	DNA-binding transcription factor activity
AM458_RS16165	COG0583	DNA-binding transcription factor activity
AM458_RS16180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM458_RS16180	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM458_RS16180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM458_RS16185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM458_RS16195	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM458_RS16200	COG3037	sugar-specific permease SgaT UlaA
AM458_RS16210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS16215	COG1609	Transcriptional regulator
AM458_RS16225	COG2223	nitrite transmembrane transporter activity
AM458_RS16255	COG0477	Major facilitator Superfamily
AM458_RS16260	COG4529	Protein conserved in bacteria
AM458_RS16265	COG1902	pentaerythritol trinitrate reductase activity
AM458_RS16275	COG0583	DNA-binding transcription factor activity
AM458_RS16280	COG2070	2-Nitropropane dioxygenase
AM458_RS16290	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM458_RS16300	COG0765	amino acid transport
AM458_RS16365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM458_RS16405	COG1335	isochorismatase
AM458_RS16415	COG0406	alpha-ribazole phosphatase activity
AM458_RS16450	COG1953	Uracil, thiamine, allantoin
AM458_RS16455	COG0402	S-adenosylhomocysteine deaminase activity
AM458_RS16460	COG3706	GGDEF domain
AM458_RS16465	COG1609	Transcriptional regulator
AM458_RS16475	COG0673	inositol 2-dehydrogenase activity
AM458_RS16485	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM458_RS16490	COG1116	anion transmembrane transporter activity
AM458_RS16495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM458_RS16500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM458_RS16505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM458_RS16510	COG0076	glutamate decarboxylase activity
AM458_RS16525	COG2205	protein histidine kinase activity
AM458_RS16535	COG0596	Alpha beta hydrolase
AM458_RS16575	COG0519	Catalyzes the synthesis of GMP from XMP
AM458_RS16575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM458_RS16595	COG0583	DNA-binding transcription factor activity
AM458_RS16605	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM458_RS16610	COG1285	pathogenesis
AM458_RS16620	COG2814	Major facilitator Superfamily
AM458_RS16625	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM458_RS16630	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS16655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS16660	COG0583	DNA-binding transcription factor activity
AM458_RS16665	COG0243	molybdopterin cofactor binding
AM458_RS16670	COG3781	membrane
AM458_RS16695	COG1764	response to oxidative stress
AM458_RS16700	COG3111	PFAM Bacterial OB fold (BOF) protein
AM458_RS16710	COG2323	membrane
AM458_RS16720	COG0366	Alpha amylase catalytic
AM458_RS16730	COG3685	Protein conserved in bacteria
AM458_RS16745	COG3729	General stress protein
AM458_RS16750	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS16790	COG0488	(ABC) transporter
AM458_RS16805	COG1064	alcohol dehydrogenase
AM458_RS16810	COG0747	negative chemotaxis
AM458_RS16820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM458_RS16830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM458_RS16840	COG2814	Major facilitator Superfamily
AM458_RS16850	COG2326	polyphosphate kinase activity
AM458_RS16865	COG2864	formate dehydrogenase
AM458_RS16870	COG0437	4 iron, 4 sulfur cluster binding
AM458_RS16895	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM458_RS16905	COG3485	protocatechuate 3,4-dioxygenase
AM458_RS16910	COG4829	muconolactone delta-isomerase
AM458_RS16915	COG4948	Mandelate Racemase Muconate Lactonizing
AM458_RS16920	COG1414	Transcriptional regulator
AM458_RS16940	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM458_RS16945	COG1140	nitrate reductase beta subunit
AM458_RS16950	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM458_RS16955	COG2181	nitrate reductase activity
AM458_RS16960	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AM458_RS16965	COG1178	ABC-type Fe3 transport system permease component
AM458_RS16970	COG1840	ABC-type Fe3 transport system, periplasmic component
AM458_RS16975	COG3842	ATPase activity
AM458_RS16980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM458_RS16995	COG2211	Major facilitator Superfamily
AM458_RS17025	COG0625	glutathione transferase activity
AM458_RS17035	COG1126	abc transporter atp-binding protein
AM458_RS17040	COG0765	amino acid transport
AM458_RS17050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM458_RS17055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM458_RS17060	COG1473	amidohydrolase
AM458_RS17065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM458_RS17070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM458_RS17095	COG4772	TonB-dependent receptor
AM458_RS17100	COG1228	amidohydrolase
AM458_RS17105	COG3691	Protein conserved in bacteria
AM458_RS17120	COG2130	NADP-dependent
AM458_RS17130	COG1247	-acetyltransferase
AM458_RS17135	COG3238	Protein conserved in bacteria
AM458_RS17145	COG0747	negative chemotaxis
AM458_RS17150	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS17180	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS17185	COG1177	transmembrane transport
AM458_RS17190	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM458_RS17195	COG3842	ATPase activity
AM458_RS17200	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM458_RS17205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM458_RS17210	COG1271	oxidase subunit
AM458_RS17215	COG1294	oxidase, subunit
AM458_RS17235	COG0826	peptidase U32
AM458_RS17245	COG1396	sequence-specific DNA binding
AM458_RS17250	COG3135	benzoate transporter
AM458_RS17255	COG3708	Transcriptional regulator
AM458_RS17255	COG2207	Transcriptional regulator
AM458_RS17270	COG0500	methyltransferase
AM458_RS17275	COG1275	C4-dicarboxylate transporter malic acid transport protein
AM458_RS17280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM458_RS17285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM458_RS17300	COG2272	Belongs to the type-B carboxylesterase lipase family
AM458_RS17305	COG5383	Protein conserved in bacteria
AM458_RS17310	COG3485	protocatechuate 3,4-dioxygenase
AM458_RS17315	COG3485	protocatechuate 3,4-dioxygenase
AM458_RS17320	COG0583	DNA-binding transcription factor activity
AM458_RS17340	COG3038	cytochrome b561
AM458_RS17360	COG2814	Major facilitator Superfamily
AM458_RS17370	COG0673	inositol 2-dehydrogenase activity
AM458_RS17380	COG2723	6-phospho-beta-galactosidase activity
AM458_RS17415	COG4659	FMN binding
AM458_RS17425	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM458_RS17440	COG0625	glutathione transferase activity
AM458_RS17445	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM458_RS17460	COG3895	Periplasmic Protein
AM458_RS17475	COG3706	GGDEF domain
AM458_RS17490	COG1566	PFAM secretion protein HlyD family protein
AM458_RS17495	COG1289	transmembrane transporter activity
AM458_RS17500	COG2032	superoxide dismutase activity
AM458_RS17505	COG4989	oxidoreductase activity
AM458_RS17510	COG3313	Fe-S protein
AM458_RS17515	COG1309	transcriptional regulator
AM458_RS17520	COG1902	pentaerythritol trinitrate reductase activity
AM458_RS17525	COG0346	lactoylglutathione lyase activity
AM458_RS17535	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM458_RS17540	COG0791	NLP P60 protein
AM458_RS17555	COG2814	Major facilitator Superfamily
AM458_RS17570	COG0583	DNA-binding transcription factor activity
AM458_RS17575	COG2814	Major facilitator Superfamily
AM458_RS17580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM458_RS17585	COG0307	riboflavin synthase, alpha
AM458_RS17640	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AM458_RS17670	COG1349	DNA-binding transcription factor activity
AM458_RS17675	COG0346	lactoylglutathione lyase activity
AM458_RS17700	COG0444	Belongs to the ABC transporter superfamily
AM458_RS17705	COG4608	Belongs to the ABC transporter superfamily
AM458_RS17735	COG0604	alcohol dehydrogenase
AM458_RS17735	COG3321	synthase
AM458_RS17735	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS17780	COG0402	S-adenosylhomocysteine deaminase activity
AM458_RS17805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM458_RS17810	COG0277	FAD linked oxidase domain protein
AM458_RS17835	COG0583	DNA-binding transcription factor activity
AM458_RS17845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM458_RS17855	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM458_RS17860	COG2610	gluconate transmembrane transporter activity
AM458_RS17865	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS17900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM458_RS17920	COG0745	RESPONSE REGULATOR receiver
AM458_RS17925	COG5002	protein histidine kinase activity
AM458_RS17925	COG3850	Histidine kinase
AM458_RS17940	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AM458_RS17980	COG3088	subunit of a heme lyase
AM458_RS17980	COG4235	cytochrome complex assembly
AM458_RS17985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM458_RS17990	COG1138	Cytochrome C-type biogenesis protein
AM458_RS18005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM458_RS18010	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM458_RS18015	COG4133	protoheme IX ABC transporter activity
AM458_RS18045	COG1175	transmembrane transport
AM458_RS18060	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM458_RS18065	COG3383	formate dehydrogenase (NAD+) activity
AM458_RS18070	COG1473	amidohydrolase
AM458_RS18100	COG1126	abc transporter atp-binding protein
AM458_RS18105	COG0765	amino acid transport
AM458_RS18125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM458_RS18130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM458_RS18135	COG1120	ATPase activity
AM458_RS18140	COG4774	siderophore transport
AM458_RS18145	COG1116	anion transmembrane transporter activity
AM458_RS18150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM458_RS18170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM458_RS18175	COG0583	DNA-binding transcription factor activity
AM458_RS18195	COG2814	Major facilitator Superfamily
AM458_RS18230	COG1414	Transcriptional regulator
AM458_RS18235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM458_RS18240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM458_RS18245	COG1120	ATPase activity
AM458_RS18255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM458_RS18260	COG2271	Major facilitator Superfamily
AM458_RS18265	COG1082	Xylose isomerase domain protein TIM barrel
AM458_RS18265	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AM458_RS18270	COG1309	transcriptional regulator
AM458_RS18295	COG1376	ErfK ybiS ycfS ynhG family protein
AM458_RS18310	COG0719	Fe-S assembly protein
AM458_RS18315	COG0396	ATPase activity
AM458_RS18320	COG0719	Fe-S assembly protein
AM458_RS18325	COG0316	Belongs to the HesB IscA family
AM458_RS18340	COG1309	transcriptional regulator
AM458_RS18345	COG1304	FMN binding
AM458_RS18370	COG0583	DNA-binding transcription factor activity
AM458_RS18380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM458_RS18385	COG1120	ATPase activity
AM458_RS18415	COG2261	transglycosylase associated protein
AM458_RS18420	COG2050	protein possibly involved in aromatic compounds catabolism
AM458_RS18425	COG0247	lactate metabolic process
AM458_RS18425	COG0277	FAD linked oxidase domain protein
AM458_RS18430	COG0628	permease
AM458_RS18440	COG0574	Belongs to the PEP-utilizing enzyme family
AM458_RS18440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM458_RS18450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM458_RS18455	COG4256	Hemin uptake protein
AM458_RS18465	COG0791	NLP P60 protein
AM458_RS18475	COG0386	Belongs to the glutathione peroxidase family
AM458_RS18495	COG0583	DNA-binding transcription factor activity
AM458_RS18515	COG0072	phenylalanine-tRNA ligase activity
AM458_RS18515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM458_RS18555	COG3137	Salt-induced outer membrane protein
AM458_RS18560	COG1105	Belongs to the carbohydrate kinase PfkB family
AM458_RS18570	COG3001	Fructosamine kinase
AM458_RS18580	COG2350	Protein conserved in bacteria
AM458_RS18585	COG2353	YceI-like domain
AM458_RS18605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM458_RS18615	COG0444	Belongs to the ABC transporter superfamily
AM458_RS18620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM458_RS18625	COG0601	transmembrane transport
AM458_RS18630	COG4166	transmembrane transport
AM458_RS18635	COG2095	MarC family integral membrane protein
AM458_RS18645	COG1454	alcohol dehydrogenase
AM458_RS18645	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS18650	COG1435	thymidine kinase activity
AM458_RS18655	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM458_RS18660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM458_RS18665	COG0745	RESPONSE REGULATOR receiver
AM458_RS18670	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM458_RS18680	COG0788	formyltetrahydrofolate deformylase activity
AM458_RS18715	COG1522	sequence-specific DNA binding
AM458_RS18725	COG2181	nitrate reductase activity
AM458_RS18730	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM458_RS18735	COG1140	nitrate reductase beta subunit
AM458_RS18740	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM458_RS18745	COG2223	nitrite transmembrane transporter activity
AM458_RS18750	COG3850	Histidine kinase
AM458_RS18755	COG2197	response regulator
AM458_RS18760	COG4932	domain protein
AM458_RS18765	COG0243	molybdopterin cofactor binding
AM458_RS18770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM458_RS18770	COG2146	nitrite reductase [NAD(P)H] activity
AM458_RS18775	COG1116	anion transmembrane transporter activity
AM458_RS18785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM458_RS18790	COG3707	response regulator
AM458_RS18795	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM458_RS18805	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM458_RS18810	COG4572	Cation transport regulator
AM458_RS18815	COG0387	Pfam Sodium calcium exchanger
AM458_RS18835	COG2890	protein-(glutamine-N5) methyltransferase activity
AM458_RS18870	COG0659	secondary active sulfate transmembrane transporter activity
AM458_RS18890	COG0012	GTP binding
AM458_RS18970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM458_RS19040	COG2885	chlorophyll binding
AM458_RS19065	COG3122	Protein conserved in bacteria
AM458_RS19080	COG0583	DNA-binding transcription factor activity
AM458_RS19110	COG0583	DNA-binding transcription factor activity
AM458_RS19140	COG1882	Formate acetyltransferase
AM458_RS19155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM458_RS19160	COG0583	DNA-binding transcription factor activity
AM458_RS19200	COG2308	Evidence 4 Homologs of previously reported genes of
AM458_RS19215	COG4774	siderophore transport
AM458_RS19225	COG1619	proteins homologs of microcin C7 resistance protein MccF
AM458_RS19245	COG2719	SpoVR family
AM458_RS19275	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM458_RS19290	COG2894	cell division
AM458_RS19300	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM458_RS19310	COG3065	identical protein binding
AM458_RS19320	COG1199	ATP-dependent helicase activity
AM458_RS19325	COG0251	oxidation-reduction process
AM458_RS19345	COG1760	l-serine dehydratase
AM458_RS19350	COG2200	EAL domain
AM458_RS19355	COG1253	flavin adenine dinucleotide binding
AM458_RS19360	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS19360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM458_RS19365	COG3715	PTS system
AM458_RS19370	COG3716	PTS system mannose fructose sorbose family IID component
AM458_RS19385	COG2226	methyltransferase
AM458_RS19390	COG0768	penicillin binding
AM458_RS19430	COG1414	Transcriptional regulator
AM458_RS19440	COG2814	Major facilitator Superfamily
AM458_RS19460	COG1956	GAF domain-containing protein
AM458_RS19465	COG2995	paraquat-inducible protein a
AM458_RS19470	COG3008	intermembrane lipid transfer
AM458_RS19495	COG2990	Protein conserved in bacteria
AM458_RS19510	COG1276	copper resistance
AM458_RS19515	COG2372	response to copper ion
AM458_RS19525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM458_RS19530	COG1770	oligopeptidase
AM458_RS19535	COG2979	Protein of unknown function (DUF533)
AM458_RS19540	COG3141	response to X-ray
AM458_RS19550	COG0800	Aldolase
AM458_RS19555	COG0129	dihydroxy-acid dehydratase activity
AM458_RS19560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM458_RS19575	COG1737	Transcriptional regulator
AM458_RS19585	COG1560	Kdo2-lipid A biosynthetic process
AM458_RS19590	COG0739	heme binding
AM458_RS19595	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM458_RS19605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM458_RS19630	COG0494	nUDIX hydrolase
AM458_RS19640	COG1335	isochorismatase
AM458_RS19645	COG1801	Protein of unknown function DUF72
AM458_RS19650	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM458_RS19670	COG3102	Protein conserved in bacteria
AM458_RS19680	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AM458_RS19705	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM458_RS19715	COG1879	ABC-type sugar transport system periplasmic component
AM458_RS19725	COG1528	Iron-storage protein
AM458_RS19735	COG2211	Major facilitator Superfamily
AM458_RS19745	COG0477	Major facilitator Superfamily
AM458_RS19760	COG1528	Iron-storage protein
AM458_RS19770	COG0814	amino acid
AM458_RS19775	COG3318	Belongs to the UPF0149 family
AM458_RS19775	COG3012	SEC-C Motif Domain Protein
AM458_RS19810	COG2197	response regulator
AM458_RS19820	COG2197	response regulator
AM458_RS19825	COG1126	abc transporter atp-binding protein
AM458_RS19830	COG0765	amino acid transport
AM458_RS19840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM458_RS19845	COG0366	Alpha amylase catalytic
AM458_RS19875	COG2354	Protein conserved in bacteria
AM458_RS19880	COG0697	spore germination
AM458_RS19885	COG3727	T/G mismatch-specific endonuclease activity
AM458_RS19890	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM458_RS19895	COG1418	mRNA catabolic process
AM458_RS19905	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM458_RS19955	COG0582	viral genome integration into host DNA
AM458_RS20055	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM458_RS20095	COG0025	NhaP-type Na H and K H
AM458_RS20100	COG1309	transcriptional regulator
AM458_RS20105	COG0604	alcohol dehydrogenase
AM458_RS20125	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM458_RS20135	COG0534	Mate efflux family protein
AM458_RS20145	COG0582	viral genome integration into host DNA
AM458_RS20155	COG1121	(ABC) transporter
AM458_RS20160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM458_RS20165	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM458_RS20195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AM458_RS20205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM458_RS20210	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM458_RS20220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM458_RS20250	COG0523	cobalamin synthesis protein
AM458_RS20280	COG0523	cobalamin synthesis protein
AM458_RS20290	COG0735	belongs to the Fur family
AM458_RS20295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM458_RS20315	COG0582	viral genome integration into host DNA
AM458_RS20320	COG1169	isochorismate synthase
AM458_RS20325	COG2814	Major facilitator Superfamily
AM458_RS20330	COG1132	(ABC) transporter
AM458_RS20345	COG3433	isochorismatase activity
AM458_RS20345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM458_RS20345	COG2226	methyltransferase
AM458_RS20365	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM458_RS20370	COG4771	TonB-dependent receptor
AM458_RS20445	COG3504	Conjugal transfer protein
AM458_RS20495	COG4227	nucleotidyltransferase activity
AM458_RS20510	COG0758	DNA mediated transformation
AM458_RS20545	COG3706	GGDEF domain
AM458_RS20570	COG3615	Tellurite resistance protein tehB
AM458_RS20575	COG3300	MHYT domain
AM458_RS20575	COG5001	Diguanylate cyclase
AM458_RS20590	COG0477	Major facilitator Superfamily
AM458_RS20595	COG0095	Lipoate-protein ligase
AM458_RS20600	COG0583	DNA-binding transcription factor activity
AM458_RS20605	COG1942	4-Oxalocrotonate Tautomerase
AM458_RS20615	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM458_RS20635	COG1289	transmembrane transporter activity
AM458_RS20650	COG2925	Exonuclease
AM458_RS20655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM458_RS20660	COG0640	Transcriptional regulator
AM458_RS20665	COG0531	amino acid
AM458_RS20675	COG0583	DNA-binding transcription factor activity
AM458_RS20680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM458_RS20710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM458_RS20730	COG1215	transferase activity, transferring glycosyl groups
AM458_RS20735	COG0438	transferase activity, transferring glycosyl groups
AM458_RS20815	COG1088	dTDP-glucose 4,6-dehydratase activity
AM458_RS20845	COG0438	transferase activity, transferring glycosyl groups
AM458_RS20855	COG1216	Glycosyl transferase, family 2
AM458_RS20855	COG1442	glycosyl transferase family 8
AM458_RS20910	COG1253	flavin adenine dinucleotide binding
AM458_RS20915	COG2982	Protein involved in outer membrane biogenesis
AM458_RS20930	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AM458_RS20940	COG0443	Heat shock 70 kDa protein
AM458_RS20945	COG5002	protein histidine kinase activity
AM458_RS20960	COG1301	dicarboxylic acid transport
AM458_RS20985	COG2205	protein histidine kinase activity
AM458_RS20990	COG0745	RESPONSE REGULATOR receiver
AM458_RS20995	COG0826	peptidase U32
AM458_RS21005	COG4608	Belongs to the ABC transporter superfamily
AM458_RS21010	COG0444	Belongs to the ABC transporter superfamily
AM458_RS21015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM458_RS21020	COG0601	transmembrane transport
AM458_RS21025	COG0747	negative chemotaxis
AM458_RS21030	COG4948	Mandelate Racemase Muconate Lactonizing
AM458_RS21035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM458_RS21045	COG1070	Carbohydrate kinase
AM458_RS21080	COG1830	Aldolase
AM458_RS21085	COG0351	phosphomethylpyrimidine kinase
AM458_RS21100	COG0583	DNA-binding transcription factor activity
AM458_RS21110	COG2252	PERMEase
AM458_RS21115	COG0583	DNA-binding transcription factor activity
AM458_RS21120	COG5455	response to cobalt ion
AM458_RS21140	COG4807	Protein conserved in bacteria
AM458_RS21150	COG3275	phosphorelay sensor kinase activity
AM458_RS21160	COG1174	glycine betaine transport
AM458_RS21165	COG1125	glycine betaine transport
AM458_RS21170	COG1174	glycine betaine transport
AM458_RS21175	COG1732	Glycine betaine
AM458_RS21180	COG1472	Belongs to the glycosyl hydrolase 3 family
AM458_RS21185	COG0277	FAD linked oxidase domain protein
AM458_RS21195	COG1686	Belongs to the peptidase S11 family
AM458_RS21205	COG0586	Pfam SNARE associated Golgi protein
AM458_RS21210	COG1538	Outer membrane efflux protein
AM458_RS21220	COG2723	6-phospho-beta-galactosidase activity
AM458_RS21235	COG3659	wide pore channel activity
AM458_RS21240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM458_RS21250	COG1346	cytolysis
AM458_RS21260	COG2949	membrane
AM458_RS21270	COG1129	ABC transporter
AM458_RS21285	COG2311	Membrane
AM458_RS21300	COG4771	TonB-dependent receptor
AM458_RS21310	COG0833	amino acid
AM458_RS21315	COG0583	DNA-binding transcription factor activity
AM458_RS21325	COG2855	membrane
AM458_RS21335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM458_RS21335	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM458_RS21335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM458_RS21340	COG1105	Belongs to the carbohydrate kinase PfkB family
AM458_RS21345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS21345	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS21375	COG1312	Catalyzes the dehydration of D-mannonate
AM458_RS21380	COG0246	Mannitol dehydrogenase
AM458_RS21385	COG0523	cobalamin synthesis protein
AM458_RS21390	COG0671	phosphoesterase, PA-phosphatase related
AM458_RS21395	COG0791	NLP P60 protein
AM458_RS21400	COG2200	EAL domain
AM458_RS21405	COG4166	transmembrane transport
AM458_RS21410	COG4174	ABC transporter (Permease)
AM458_RS21415	COG4239	(ABC) transporter, permease
AM458_RS21420	COG4172	Belongs to the ABC transporter superfamily
AM458_RS21430	COG2814	Major facilitator Superfamily
AM458_RS21435	COG1187	pseudouridine synthase activity
AM458_RS21440	COG1061	Type III restriction enzyme res subunit
AM458_RS21460	COG0494	nUDIX hydrolase
AM458_RS21465	COG1349	DNA-binding transcription factor activity
AM458_RS21490	COG0628	permease
AM458_RS21505	COG0659	secondary active sulfate transmembrane transporter activity
AM458_RS21510	COG2239	Acts as a magnesium transporter
AM458_RS21515	COG4615	Cyclic peptide transporter
AM458_RS21520	COG3145	DNA-N1-methyladenine dioxygenase activity
AM458_RS21525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM458_RS21525	COG2169	Transcriptional regulator
AM458_RS21540	COG0642	Histidine kinase
AM458_RS21540	COG2198	Histidine kinase
AM458_RS21550	COG2205	protein histidine kinase activity
AM458_RS21550	COG0784	Response regulator, receiver
AM458_RS21580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM458_RS21590	COG0584	glycerophosphoryl diester phosphodiesterase
AM458_RS21595	COG2271	Major facilitator Superfamily
AM458_RS21600	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM458_RS21610	COG0247	lactate metabolic process
AM458_RS21620	COG2271	Major facilitator Superfamily
AM458_RS21630	COG1414	Transcriptional regulator
AM458_RS21645	COG5464	transposase or invertase
AM458_RS21655	COG0318	PFAM AMP-dependent synthetase and ligase
AM458_RS21680	COG1169	isochorismate synthase
AM458_RS21685	COG2153	protein acetylation
AM458_RS21700	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM458_RS21705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM458_RS21715	COG0839	Belongs to the complex I subunit 6 family
AM458_RS21770	COG0583	DNA-binding transcription factor activity
AM458_RS21775	COG0436	Aminotransferase
AM458_RS21785	COG0471	metal ion transport
AM458_RS21785	COG0490	domain, Protein
AM458_RS21790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM458_RS21810	COG0280	phosphate acetyltransferase
AM458_RS21810	COG0857	belongs to the CobB CobQ family
AM458_RS21815	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM458_RS21820	COG0622	Phosphoesterase
AM458_RS21825	COG0625	glutathione transferase activity
AM458_RS21830	COG0625	glutathione transferase activity
AM458_RS21835	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM458_RS21840	COG1090	epimerase
AM458_RS21850	COG4598	ABC transporter
AM458_RS21855	COG4160	amino acid transport
AM458_RS21875	COG0163	prenyltransferase activity
AM458_RS21880	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM458_RS21885	COG1286	toxin biosynthetic process
AM458_RS21890	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM458_RS21895	COG0285	dihydrofolate synthase activity
AM458_RS21905	COG0586	Pfam SNARE associated Golgi protein
AM458_RS21915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM458_RS21935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM458_RS21950	COG3101	peptidyl-lysine hydroxylation
AM458_RS21955	COG0730	response to heat
AM458_RS21980	COG2062	phosphohistidine phosphatase, SixA
AM458_RS21995	COG3691	Protein conserved in bacteria
AM458_RS22010	COG2853	Lipoprotein
AM458_RS22015	COG2116	formate transmembrane transporter activity
AM458_RS22030	COG0582	viral genome integration into host DNA
AM458_RS22035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM458_RS22180	COG3567	Phage-associated protein, HI1409 family
AM458_RS22185	COG1783	phage Terminase large subunit
AM458_RS22200	COG3772	lysozyme
AM458_RS22220	COG0484	heat shock protein binding
AM458_RS22385	COG0582	viral genome integration into host DNA
AM458_RS22390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM458_RS22535	COG3567	Phage-associated protein, HI1409 family
AM458_RS22540	COG1783	phage Terminase large subunit
AM458_RS22555	COG3772	lysozyme
AM458_RS22575	COG0484	heat shock protein binding
AM458_RS22745	COG0583	DNA-binding transcription factor activity
AM458_RS22750	COG0590	tRNA wobble adenosine to inosine editing
AM458_RS22755	COG2807	transmembrane transport
AM458_RS22765	COG0436	Aminotransferase
AM458_RS22775	COG3275	phosphorelay sensor kinase activity
AM458_RS22780	COG3279	Response regulator of the LytR AlgR family
AM458_RS22795	COG3961	Belongs to the TPP enzyme family
AM458_RS22800	COG0667	Aldo Keto reductase
AM458_RS22815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM458_RS22820	COG2200	EAL domain
AM458_RS22820	COG2199	diguanylate cyclase activity
AM458_RS22835	COG3415	Transposase
AM458_RS22840	COG3415	Transposase
AM458_RS22875	COG0583	DNA-binding transcription factor activity
AM458_RS22880	COG0385	Bile acid
AM458_RS22885	COG3530	Putative quorum-sensing-regulated virulence factor
AM458_RS22905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM458_RS22940	COG4319	ketosteroid isomerase
AM458_RS22950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM458_RS22955	COG4208	sulfate ABC transporter
AM458_RS22960	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM458_RS22965	COG4150	thiosulfate binding
AM458_RS22975	COG2837	iron assimilation
AM458_RS22995	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM458_RS23085	COG4810	utilization protein
AM458_RS23095	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM458_RS23100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM458_RS23105	COG5342	invasion associated locus B
AM458_RS23115	COG0493	'glutamate synthase
AM458_RS23115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM458_RS23125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM458_RS23135	COG1393	Belongs to the ArsC family
AM458_RS23150	COG0400	carboxylic ester hydrolase activity
AM458_RS23155	COG1444	tRNA N-acetyltransferase activity
AM458_RS23160	COG2321	neutral zinc metallopeptidase
AM458_RS23170	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM458_RS23180	COG2716	regulation of RNA biosynthetic process
AM458_RS23185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM458_RS23190	COG0628	permease
AM458_RS23195	COG4783	chaperone-mediated protein folding
AM458_RS23200	COG1393	Belongs to the ArsC family
AM458_RS23215	COG2233	PERMEase
AM458_RS23225	COG2723	6-phospho-beta-galactosidase activity
AM458_RS23240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM458_RS23255	COG2200	EAL domain
AM458_RS23275	COG0641	radical SAM
AM458_RS23280	COG3119	arylsulfatase activity
AM458_RS23290	COG3179	chitinase
AM458_RS23425	COG5484	DNA packaging
AM458_RS23425	COG3728	DNA packaging
AM458_RS23440	COG3344	reverse transcriptase
AM458_RS23515	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM458_RS23565	COG0517	IMP dehydrogenase activity
AM458_RS23565	COG0516	GMP reductase activity
AM458_RS23575	COG1645	bacterial-type flagellum-dependent swarming motility
AM458_RS23595	COG2976	Protein conserved in bacteria
AM458_RS23630	COG4953	penicillin-binding protein 1C
AM458_RS23635	COG2373	Large extracellular alpha-helical protein
AM458_RS23640	COG2897	thiosulfate sulfurtransferase activity
AM458_RS23660	COG2975	iron-sulfur cluster assembly
AM458_RS23665	COG0633	Ferredoxin
AM458_RS23685	COG0822	iron-sulfur transferase activity
AM458_RS23715	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM458_RS23720	COG3683	transport system, periplasmic component
AM458_RS23725	COG3711	transcriptional antiterminator
AM458_RS23730	COG2814	Major facilitator Superfamily
AM458_RS23735	COG2017	converts alpha-aldose to the beta-anomer
AM458_RS23740	COG2814	Major facilitator Superfamily
AM458_RS23740	COG0477	Major facilitator Superfamily
AM458_RS23745	COG0457	Tetratricopeptide repeat
AM458_RS23750	COG1940	carbohydrate kinase activity
AM458_RS23755	COG2259	Doxx family
AM458_RS23770	COG1017	nitric oxide dioxygenase activity
AM458_RS23770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM458_RS23775	COG0347	Belongs to the P(II) protein family
AM458_RS23780	COG2204	response regulator
AM458_RS23785	COG3170	Tfp pilus assembly protein FimV
AM458_RS23790	COG2205	protein histidine kinase activity
AM458_RS23795	COG0047	phosphoribosylformylglycinamidine synthase activity
AM458_RS23795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM458_RS23810	COG0560	Phosphoserine phosphatase
AM458_RS23815	COG1737	Transcriptional regulator
AM458_RS23820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM458_RS23830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM458_RS23850	COG0681	Belongs to the peptidase S26 family
AM458_RS23860	COG3086	response to oxidative stress
AM458_RS23865	COG3026	antisigma factor binding
AM458_RS23870	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AM458_RS23880	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM458_RS23890	COG0513	Belongs to the DEAD box helicase family
AM458_RS23905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM458_RS23910	COG3118	belongs to the thioredoxin family
AM458_RS23915	COG3148	PFAM DTW domain containing protein
AM458_RS23925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM458_RS23930	COG5544	Lipoprotein
AM458_RS23935	COG0477	Major facilitator Superfamily
AM458_RS23960	COG0542	response to heat
AM458_RS23975	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM458_RS23980	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM458_RS23990	COG0077	Prephenate dehydratase
AM458_RS23990	COG1605	Chorismate mutase
AM458_RS24000	COG0287	Prephenate dehydrogenase
AM458_RS24000	COG1605	Chorismate mutase
AM458_RS24005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM458_RS24015	COG2199	diguanylate cyclase activity
AM458_RS24020	COG2885	chlorophyll binding
AM458_RS24080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM458_RS24120	COG4695	Portal protein
AM458_RS24275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM458_RS24280	COG4137	Cytochrome C assembly protein
AM458_RS24285	COG4536	flavin adenine dinucleotide binding
AM458_RS24305	COG0497	DNA recombination
AM458_RS24320	COG2867	negative regulation of translational initiation
AM458_RS24485	COG4695	Portal protein
AM458_RS24530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM458_RS24565	COG4974	Belongs to the 'phage' integrase family
AM458_RS24590	COG2207	Transcriptional regulator
AM458_RS24590	COG3708	Transcriptional regulator
AM458_RS24595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM458_RS24630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM458_RS24640	COG0235	Class ii aldolase
AM458_RS24650	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS24665	COG2197	response regulator
AM458_RS24670	COG3539	Fimbrial protein
AM458_RS24680	COG3188	usher protein
AM458_RS24700	COG3121	Chaperone
AM458_RS24705	COG3539	Fimbrial protein
AM458_RS24715	COG3284	Transcriptional regulator
AM458_RS24720	COG0583	DNA-binding transcription factor activity
AM458_RS24730	COG0640	Transcriptional regulator
AM458_RS24735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM458_RS24750	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM458_RS24775	COG4575	ribosome binding
AM458_RS24780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM458_RS24785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM458_RS24790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM458_RS24800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM458_RS24815	COG4176	ABC-type proline glycine betaine transport system permease component
AM458_RS24825	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM458_RS24835	COG1846	Transcriptional regulator
AM458_RS24840	COG1566	PFAM secretion protein HlyD family protein
AM458_RS24845	COG2814	Major facilitator Superfamily
AM458_RS24850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM458_RS24870	COG1238	metal cluster binding
AM458_RS24875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM458_RS24880	COG2823	Periplasmic or secreted lipoprotein
AM458_RS24910	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM458_RS24935	COG1546	Belongs to the CinA family
AM458_RS24945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM458_RS24950	COG1121	(ABC) transporter
AM458_RS24960	COG2951	lytic endotransglycosylase activity
AM458_RS24965	COG3730	PTS system glucitol sorbitol-specific
AM458_RS24970	COG3732	PTS system glucitol sorbitol-specific
AM458_RS24980	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS24985	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS24990	COG1349	DNA-binding transcription factor activity
AM458_RS25020	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AM458_RS25025	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM458_RS25030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM458_RS25035	COG1609	Transcriptional regulator
AM458_RS25040	COG1263	PTS System
AM458_RS25040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM458_RS25045	COG2723	6-phospho-beta-galactosidase activity
AM458_RS25055	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM458_RS25065	COG3260	NADH ubiquinone oxidoreductase 20
AM458_RS25070	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM458_RS25075	COG3261	NADH dehydrogenase
AM458_RS25075	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM458_RS25080	COG0650	Formate hydrogenlyase subunit 4
AM458_RS25085	COG0651	ATP synthesis coupled electron transport
AM458_RS25090	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM458_RS25110	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM458_RS25115	COG0298	carbon dioxide binding
AM458_RS25120	COG0409	Hydrogenase expression formation protein
AM458_RS25125	COG0309	Hydrogenase expression formation protein (HypE)
AM458_RS25135	COG2723	6-phospho-beta-galactosidase activity
AM458_RS25145	COG4580	involved in the transport of maltose and maltodextrins
AM458_RS25155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS25160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS25165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS25170	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM458_RS25175	COG1940	carbohydrate kinase activity
AM458_RS25180	COG1609	Transcriptional regulator
AM458_RS25185	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM458_RS25190	COG1121	(ABC) transporter
AM458_RS25195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM458_RS25200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM458_RS25215	COG0679	Auxin Efflux Carrier
AM458_RS25235	COG3720	iron ion transport
AM458_RS25240	COG4558	Periplasmic binding protein
AM458_RS25245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM458_RS25290	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM458_RS25295	COG0163	prenyltransferase activity
AM458_RS25320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM458_RS25325	COG1388	LysM domain
AM458_RS25325	COG4942	peptidase
AM458_RS25385	COG2234	aminopeptidase activity
AM458_RS25405	COG0720	synthase
AM458_RS25410	COG0602	queuosine metabolic process
AM458_RS25430	COG3956	TIGRFAM MazG family protein
AM458_RS25435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM458_RS25445	COG2205	protein histidine kinase activity
AM458_RS25445	COG4999	Histidine kinase
AM458_RS25445	COG3850	Histidine kinase
AM458_RS25445	COG3437	response regulator, receiver
AM458_RS25450	COG1929	Belongs to the glycerate kinase type-1 family
AM458_RS25455	COG4948	Mandelate Racemase Muconate Lactonizing
AM458_RS25460	COG4948	Mandelate Racemase Muconate Lactonizing
AM458_RS25465	COG2271	Major facilitator Superfamily
AM458_RS25470	COG0716	FMN binding
AM458_RS25475	COG0564	pseudouridine synthase activity
AM458_RS25480	COG3098	single-species biofilm formation
AM458_RS25495	COG1611	Belongs to the LOG family
AM458_RS25500	COG0814	amino acid
AM458_RS25505	COG1760	l-serine dehydratase
AM458_RS25510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM458_RS25520	COG0477	Major facilitator Superfamily
AM458_RS25530	COG1464	Belongs to the NlpA lipoprotein family
AM458_RS25535	COG2011	ABC-type metal ion transport system permease component
AM458_RS25540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM458_RS25555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM458_RS25570	COG1454	alcohol dehydrogenase
AM458_RS25575	COG0235	Class ii aldolase
AM458_RS25580	COG0738	Major facilitator superfamily
AM458_RS25600	COG1349	DNA-binding transcription factor activity
AM458_RS25610	COG2363	Small membrane protein
AM458_RS25615	COG0583	DNA-binding transcription factor activity
AM458_RS25625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM458_RS25630	COG2166	iron-sulfur cluster assembly
AM458_RS25635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM458_RS25640	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM458_RS25805	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM458_RS25835	COG1454	alcohol dehydrogenase
AM458_RS25835	COG1012	belongs to the aldehyde dehydrogenase family
AM458_RS25840	COG4656	Part of a membrane complex involved in electron transport
AM458_RS25870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM458_RS25875	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM458_RS25880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM458_RS25880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM458_RS25890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM458_RS25895	COG1074	ATP-dependent DNA helicase activity
AM458_RS25900	COG1025	Belongs to the peptidase M16 family
AM458_RS25905	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM458_RS25910	COG4967	type IV pilus modification protein PilV
AM458_RS25920	COG4795	General secretion pathway protein
AM458_RS25925	COG2165	general secretion pathway protein
AM458_RS25955	COG0861	Integral membrane protein TerC family
AM458_RS25965	COG0667	Aldo Keto reductase
AM458_RS25990	COG1609	Transcriptional regulator
AM458_RS26000	COG2186	Transcriptional regulator
AM458_RS26005	COG2723	6-phospho-beta-galactosidase activity
AM458_RS26010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM458_RS26015	COG1609	Transcriptional regulator
AM458_RS26025	COG0583	DNA-binding transcription factor activity
AM458_RS26030	COG1794	racemase activity, acting on amino acids and derivatives
AM458_RS26035	COG1917	Cupin 2, conserved barrel domain protein
AM458_RS26040	COG1175	transmembrane transport
AM458_RS26045	COG0395	ABC-type sugar transport system, permease component
AM458_RS26050	COG3842	ATPase activity
AM458_RS26080	COG2814	Major facilitator Superfamily
AM458_RS26085	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS26090	COG0823	Involved in the tonB-independent uptake of proteins
AM458_RS26100	COG0183	Belongs to the thiolase family
AM458_RS26115	COG0814	amino acid
AM458_RS26120	COG0667	Aldo Keto reductase
AM458_RS26170	COG0697	spore germination
AM458_RS26175	COG1846	Transcriptional regulator
AM458_RS26180	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM458_RS26190	COG0582	viral genome integration into host DNA
AM458_RS26195	COG4974	Belongs to the 'phage' integrase family
AM458_RS26205	COG3539	Fimbrial protein
AM458_RS26210	COG3121	Chaperone
AM458_RS26215	COG3188	usher protein
AM458_RS26220	COG3539	Fimbrial protein
AM458_RS26225	COG3539	Fimbrial protein
AM458_RS26230	COG3539	Fimbrial protein
AM458_RS26240	COG2388	GCN5-related N-acetyl-transferase
AM458_RS26245	COG3592	Divergent 4Fe-4S mono-cluster
AM458_RS26260	COG1289	transmembrane transporter activity
AM458_RS26265	COG1538	Outer membrane efflux protein
AM458_RS26280	COG1393	Belongs to the ArsC family
AM458_RS26285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM458_RS26320	COG0667	Aldo Keto reductase
AM458_RS26335	COG2814	Major facilitator Superfamily
AM458_RS26345	COG4942	peptidase
AM458_RS26370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM458_RS26380	COG4974	Belongs to the 'phage' integrase family
AM458_RS26385	COG0716	FMN binding
AM458_RS26395	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM458_RS26405	COG1272	protein, Hemolysin III
AM458_RS26415	COG1737	Transcriptional regulator
AM458_RS26420	COG2723	6-phospho-beta-galactosidase activity
AM458_RS26440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM458_RS26445	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS26465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM458_RS26470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM458_RS26475	COG0006	proline dipeptidase activity
AM458_RS26495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM458_RS26500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM458_RS26515	COG2968	Membrane
AM458_RS26525	COG0668	transmembrane transport
AM458_RS26530	COG0191	fructose-bisphosphate aldolase activity
AM458_RS26545	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM458_RS26550	COG0501	Belongs to the peptidase M48B family
AM458_RS26570	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AM458_RS26575	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS26605	COG1414	Transcriptional regulator
AM458_RS26610	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS26625	COG2146	nitrite reductase [NAD(P)H] activity
AM458_RS26665	COG2814	Major facilitator Superfamily
AM458_RS26675	COG2356	endonuclease I
AM458_RS26680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM458_RS26685	COG0189	ligase activity
AM458_RS26705	COG2805	Type II/IV secretion system protein
AM458_RS26710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM458_RS26715	COG0762	integral membrane protein
AM458_RS26730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM458_RS26740	COG3171	Protein conserved in bacteria
AM458_RS26750	COG1194	a g-specific adenine glycosylase
AM458_RS26765	COG2211	Major facilitator Superfamily
AM458_RS26770	COG1982	Orn Lys Arg decarboxylase major
AM458_RS26780	COG1811	Na channel or pump
AM458_RS26790	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM458_RS26850	COG3423	Transcriptional regulator
AM458_RS26855	COG1278	Cold shock
AM458_RS26865	COG3423	Transcriptional regulator
AM458_RS27125	COG0626	cystathionine gamma-synthase activity
AM458_RS27150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM458_RS27155	COG0754	glutathionylspermidine amidase activity
AM458_RS27165	COG0625	glutathione transferase activity
AM458_RS27190	COG2211	Major facilitator Superfamily
AM458_RS27195	COG0848	biopolymer transport protein
AM458_RS27210	COG0626	cystathionine gamma-synthase activity
AM458_RS27215	COG0586	Pfam SNARE associated Golgi protein
AM458_RS27220	COG2207	Transcriptional regulator
AM458_RS27225	COG1979	alcohol dehydrogenase
AM458_RS27230	COG0656	L-ascorbic acid biosynthetic process
AM458_RS27240	COG1032	radical SAM domain protein
AM458_RS27245	COG2132	Multicopper oxidase
AM458_RS27250	COG0204	Acyl-transferase
AM458_RS27255	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM458_RS27260	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM458_RS27265	COG3111	PFAM Bacterial OB fold (BOF) protein
AM458_RS27275	COG0642	Histidine kinase
AM458_RS27280	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM458_RS27285	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM458_RS27295	COG3150	esterase
AM458_RS27300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM458_RS27305	COG3151	Protein conserved in bacteria
AM458_RS27310	COG0494	nUDIX hydrolase
AM458_RS27325	COG0754	glutathionylspermidine amidase activity
AM458_RS27330	COG3384	dioxygenase
AM458_RS27345	COG2960	long-chain fatty acid transporting porin activity
AM458_RS27365	COG3025	triphosphatase activity
AM458_RS27370	COG4991	sh3 domain protein
AM458_RS27385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM458_RS27450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM458_RS27455	COG0358	DNA primase activity
AM458_RS27460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM458_RS27485	COG2197	response regulator
AM458_RS27490	COG2205	protein histidine kinase activity
AM458_RS27490	COG2198	Histidine kinase
AM458_RS27490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM458_RS27490	COG0784	Response regulator, receiver
AM458_RS27500	COG3247	response to pH
AM458_RS27580	COG2376	Dihydroxyacetone kinase
AM458_RS27585	COG1461	Dihydroxyacetone kinase
AM458_RS27600	COG2375	cellular response to nickel ion
AM458_RS27605	COG1695	Transcriptional regulator
AM458_RS27660	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM458_RS27660	COG1902	pentaerythritol trinitrate reductase activity
AM458_RS27680	COG1451	nucleotide metabolic process
AM458_RS27685	COG0673	inositol 2-dehydrogenase activity
AM458_RS27690	COG0861	Integral membrane protein TerC family
AM458_RS27705	COG2721	sulfolactate sulfo-lyase activity
AM458_RS27715	COG2271	Major facilitator Superfamily
AM458_RS27720	COG2186	Transcriptional regulator
AM458_RS27725	COG0586	Pfam SNARE associated Golgi protein
AM458_RS27735	COG1422	Protein of unknown function (DUF1090)
AM458_RS27740	COG4575	ribosome binding
AM458_RS27745	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM458_RS27755	COG2259	Doxx family
AM458_RS27760	COG0435	Glutathione S-transferase
AM458_RS27765	COG3152	Membrane
AM458_RS27770	COG0583	DNA-binding transcription factor activity
AM458_RS27775	COG1741	Belongs to the pirin family
AM458_RS27795	COG1929	Belongs to the glycerate kinase type-1 family
AM458_RS27800	COG2084	Dehydrogenase
AM458_RS27810	COG2271	Major facilitator Superfamily
AM458_RS27815	COG2721	sulfolactate sulfo-lyase activity
AM458_RS27820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM458_RS27825	COG1349	DNA-binding transcription factor activity
AM458_RS27835	COG1105	Belongs to the carbohydrate kinase PfkB family
AM458_RS27840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS27840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM458_RS27840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM458_RS27845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS27845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS27855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS27860	COG3414	Phosphotransferase system galactitol-specific IIB component
AM458_RS27865	COG3775	system Galactitol-specific IIC component
AM458_RS27870	COG1063	alcohol dehydrogenase
AM458_RS27885	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM458_RS27905	COG2823	Periplasmic or secreted lipoprotein
AM458_RS27910	COG0701	Predicted permease
AM458_RS27915	COG0702	epimerase
AM458_RS27920	COG0693	protein deglycase activity
AM458_RS27935	COG3153	acetyltransferase
AM458_RS27940	COG3154	lipid carrier protein
AM458_RS27945	COG0826	peptidase U32
AM458_RS27950	COG0826	peptidase U32
AM458_RS27955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM458_RS27960	COG0814	amino acid
AM458_RS28010	COG0195	Participates in both transcription termination and antitermination
AM458_RS28050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM458_RS28060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM458_RS28065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM458_RS28075	COG1534	Rna-binding protein
AM458_RS28085	COG2027	D-alanyl-D-alanine carboxypeptidase
AM458_RS28095	COG0697	spore germination
AM458_RS28110	COG0142	geranyltranstransferase activity
AM458_RS28115	COG3423	Transcriptional regulator
AM458_RS28125	COG5007	Belongs to the BolA IbaG family
AM458_RS28130	COG3113	response to antibiotic
AM458_RS28135	COG2854	intermembrane phospholipid transfer
AM458_RS28140	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM458_RS28145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM458_RS28150	COG1127	ABC transporter
AM458_RS28160	COG0530	calcium, potassium:sodium antiporter activity
AM458_RS28170	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM458_RS28175	COG3117	lipopolysaccharide transmembrane transporter activity
AM458_RS28180	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM458_RS28185	COG1137	ATPase activity
AM458_RS28190	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM458_RS28195	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM458_RS28200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS28210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM458_RS28215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM458_RS28220	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM458_RS28225	COG0784	Response regulator, receiver
AM458_RS28225	COG5002	protein histidine kinase activity
AM458_RS28225	COG2198	Histidine kinase
AM458_RS28230	COG1312	Catalyzes the dehydration of D-mannonate
AM458_RS28235	COG1063	alcohol dehydrogenase
AM458_RS28240	COG2271	Major facilitator Superfamily
AM458_RS28245	COG1242	4 iron, 4 sulfur cluster binding
AM458_RS28255	COG0069	glutamate synthase activity
AM458_RS28255	COG0070	glutamate synthase
AM458_RS28255	COG0067	glutamate synthase
AM458_RS28260	COG0493	'glutamate synthase
AM458_RS28270	COG2969	positive regulation of protein catabolic process
AM458_RS28275	COG0625	glutathione transferase activity
AM458_RS28295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM458_RS28300	COG3105	Protein conserved in bacteria
AM458_RS28320	COG2199	diguanylate cyclase activity
AM458_RS28320	COG2203	Gaf domain
AM458_RS28325	COG5001	Diguanylate cyclase
AM458_RS28325	COG1716	ATPase activity
AM458_RS28345	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM458_RS28355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM458_RS28405	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM458_RS28435	COG0739	heme binding
AM458_RS28445	COG2132	Multicopper oxidase
AM458_RS28450	COG3667	copper resistance
AM458_RS28455	COG2372	response to copper ion
AM458_RS28460	COG1276	copper resistance
AM458_RS28465	COG0745	RESPONSE REGULATOR receiver
AM458_RS28470	COG2205	protein histidine kinase activity
AM458_RS28490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AM458_RS28505	COG0431	NADPH-dependent FMN reductase
AM458_RS28535	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM458_RS28600	COG2801	Transposase and inactivated derivatives
AM458_RS28615	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM458_RS28705	COG1983	PspC domain protein
AM458_RS28715	COG1842	Phage shock protein A
AM458_RS28720	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM458_RS28730	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS28735	COG1546	Belongs to the CinA family
AM458_RS28750	COG3111	PFAM Bacterial OB fold (BOF) protein
AM458_RS28840	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AM458_RS29065	COG5499	transcription regulator containing HTH domain
AM458_RS29145	COG1475	DNA binding
AM458_RS29220	COG3344	reverse transcriptase
AM458_RS29275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM458_RS29305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM458_RS29355	COG0459	protein refolding
AM458_RS29365	COG0583	DNA-binding transcription factor activity
AM458_RS29435	COG1660	Displays ATPase and GTPase activities
AM458_RS29495	COG1192	Involved in chromosome partitioning
AM458_RS29580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM458_RS29670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM458_RS29695	COG5001	Diguanylate cyclase
AM458_RS29730	COG0714	Associated with various cellular activities
AM458_RS29740	COG0629	single-stranded DNA binding
AM458_RS29790	COG0633	Ferredoxin
AM458_RS29960	COG4974	Belongs to the 'phage' integrase family
AM458_RS30170	COG0616	signal peptide processing
AM458_RS30290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM458_RS30435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM458_RS30490	COG3941	tape measure
AM458_RS30580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM458_RS30585	COG1475	DNA binding
AM458_RS30590	COG1475	DNA binding
AM458_RS30730	COG0328	RNA-DNA hybrid ribonuclease activity
AM458_RS30750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM458_RS30775	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AM458_RS30785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM458_RS30790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM458_RS30855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM458_RS30865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM458_RS30940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM458_RS30970	COG3064	Membrane
AM458_RS31045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM458_RS31195	COG2337	Toxic component of a toxin-antitoxin (TA) module
AM458_RS31205	COG2336	PFAM SpoVT AbrB
AM458_RS31260	COG0629	single-stranded DNA binding
AM458_RS31380	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM458_RS31395	COG2801	Transposase and inactivated derivatives
AM458_RS31440	COG1196	nuclear chromosome segregation
AM458_RS31450	COG0484	heat shock protein binding
AM458_RS31525	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AM458_RS31685	COG1475	DNA binding
AM458_RS31955	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AM458_RS32045	COG3111	PFAM Bacterial OB fold (BOF) protein
AM458_RS32060	COG1546	Belongs to the CinA family
AM458_RS32065	COG1028	Short-chain dehydrogenase reductase Sdr
AM458_RS32075	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM458_RS32080	COG1842	Phage shock protein A
AM458_RS32090	COG1983	PspC domain protein