locus-tag	class	description
AM393_RS00020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM393_RS00075	COG2885	chlorophyll binding
AM393_RS00105	COG3122	Protein conserved in bacteria
AM393_RS00120	COG0583	DNA-binding transcription factor activity
AM393_RS00150	COG0583	DNA-binding transcription factor activity
AM393_RS00180	COG1882	Formate acetyltransferase
AM393_RS00195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM393_RS00200	COG0583	DNA-binding transcription factor activity
AM393_RS00240	COG2308	Evidence 4 Homologs of previously reported genes of
AM393_RS00250	COG2211	Major facilitator Superfamily
AM393_RS00260	COG4774	siderophore transport
AM393_RS00270	COG1619	proteins homologs of microcin C7 resistance protein MccF
AM393_RS00290	COG2719	SpoVR family
AM393_RS00320	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM393_RS00335	COG2894	cell division
AM393_RS00345	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM393_RS00355	COG3065	identical protein binding
AM393_RS00365	COG1199	ATP-dependent helicase activity
AM393_RS00370	COG0251	oxidation-reduction process
AM393_RS00390	COG1760	l-serine dehydratase
AM393_RS00395	COG2200	EAL domain
AM393_RS00400	COG1253	flavin adenine dinucleotide binding
AM393_RS00405	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS00405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM393_RS00410	COG3715	PTS system
AM393_RS00415	COG3716	PTS system mannose fructose sorbose family IID component
AM393_RS00435	COG2226	methyltransferase
AM393_RS00440	COG0768	penicillin binding
AM393_RS00480	COG1414	Transcriptional regulator
AM393_RS00485	COG2814	Major facilitator Superfamily
AM393_RS00505	COG1956	GAF domain-containing protein
AM393_RS00510	COG2995	paraquat-inducible protein a
AM393_RS00515	COG3008	intermembrane lipid transfer
AM393_RS00540	COG2990	Protein conserved in bacteria
AM393_RS00585	COG1276	copper resistance
AM393_RS00590	COG2372	response to copper ion
AM393_RS00600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM393_RS00605	COG1770	oligopeptidase
AM393_RS00610	COG2979	Protein of unknown function (DUF533)
AM393_RS00615	COG3141	response to X-ray
AM393_RS00625	COG0800	Aldolase
AM393_RS00630	COG0129	dihydroxy-acid dehydratase activity
AM393_RS00635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM393_RS00650	COG1737	Transcriptional regulator
AM393_RS00660	COG1560	Kdo2-lipid A biosynthetic process
AM393_RS00665	COG0739	heme binding
AM393_RS00670	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM393_RS00680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM393_RS00705	COG0494	nUDIX hydrolase
AM393_RS00715	COG1335	isochorismatase
AM393_RS00720	COG1801	Protein of unknown function DUF72
AM393_RS00725	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM393_RS00745	COG3102	Protein conserved in bacteria
AM393_RS00755	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AM393_RS00780	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS00790	COG1879	ABC-type sugar transport system periplasmic component
AM393_RS00800	COG1528	Iron-storage protein
AM393_RS00810	COG2211	Major facilitator Superfamily
AM393_RS00820	COG0477	Major facilitator Superfamily
AM393_RS00835	COG1528	Iron-storage protein
AM393_RS00845	COG0814	amino acid
AM393_RS00850	COG3012	SEC-C Motif Domain Protein
AM393_RS00850	COG3318	Belongs to the UPF0149 family
AM393_RS00885	COG2197	response regulator
AM393_RS00895	COG2197	response regulator
AM393_RS00900	COG1126	abc transporter atp-binding protein
AM393_RS00905	COG0765	amino acid transport
AM393_RS00915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM393_RS00920	COG0366	Alpha amylase catalytic
AM393_RS00950	COG2354	Protein conserved in bacteria
AM393_RS00955	COG0697	spore germination
AM393_RS00960	COG3727	T/G mismatch-specific endonuclease activity
AM393_RS00965	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM393_RS00970	COG1418	mRNA catabolic process
AM393_RS00980	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM393_RS01030	COG0582	viral genome integration into host DNA
AM393_RS01045	COG1121	(ABC) transporter
AM393_RS01050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM393_RS01055	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM393_RS01085	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AM393_RS01095	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM393_RS01100	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM393_RS01105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM393_RS01110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM393_RS01140	COG0523	cobalamin synthesis protein
AM393_RS01170	COG0523	cobalamin synthesis protein
AM393_RS01180	COG0735	belongs to the Fur family
AM393_RS01185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM393_RS01205	COG3436	PFAM IS66 Orf2 family protein
AM393_RS01210	COG4372	Transposase
AM393_RS01215	COG1120	ATPase activity
AM393_RS01220	COG0582	viral genome integration into host DNA
AM393_RS01225	COG1169	isochorismate synthase
AM393_RS01230	COG2814	Major facilitator Superfamily
AM393_RS01235	COG1132	(ABC) transporter
AM393_RS01250	COG2226	methyltransferase
AM393_RS01250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM393_RS01250	COG3433	isochorismatase activity
AM393_RS01270	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM393_RS01275	COG4771	TonB-dependent receptor
AM393_RS01350	COG3504	Conjugal transfer protein
AM393_RS01400	COG4227	nucleotidyltransferase activity
AM393_RS01415	COG0758	DNA mediated transformation
AM393_RS01445	COG0025	NhaP-type Na H and K H
AM393_RS01450	COG1309	transcriptional regulator
AM393_RS01455	COG0604	alcohol dehydrogenase
AM393_RS01475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM393_RS01485	COG0534	Mate efflux family protein
AM393_RS01500	COG3706	GGDEF domain
AM393_RS01525	COG3615	Tellurite resistance protein tehB
AM393_RS01530	COG3300	MHYT domain
AM393_RS01530	COG5001	Diguanylate cyclase
AM393_RS01545	COG0477	Major facilitator Superfamily
AM393_RS01550	COG0095	Lipoate-protein ligase
AM393_RS01555	COG0583	DNA-binding transcription factor activity
AM393_RS01560	COG1942	4-Oxalocrotonate Tautomerase
AM393_RS01570	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM393_RS01590	COG1289	transmembrane transporter activity
AM393_RS01600	COG3344	reverse transcriptase
AM393_RS01615	COG2925	Exonuclease
AM393_RS01620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM393_RS01625	COG0640	Transcriptional regulator
AM393_RS01630	COG0531	amino acid
AM393_RS01635	COG0583	DNA-binding transcription factor activity
AM393_RS01640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM393_RS01665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM393_RS01685	COG1215	transferase activity, transferring glycosyl groups
AM393_RS01690	COG0438	transferase activity, transferring glycosyl groups
AM393_RS01760	COG3344	reverse transcriptase
AM393_RS01770	COG0438	transferase activity, transferring glycosyl groups
AM393_RS01830	COG1253	flavin adenine dinucleotide binding
AM393_RS01835	COG2982	Protein involved in outer membrane biogenesis
AM393_RS01850	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AM393_RS01855	COG0443	Heat shock 70 kDa protein
AM393_RS01860	COG5002	protein histidine kinase activity
AM393_RS01875	COG1301	dicarboxylic acid transport
AM393_RS01900	COG2205	protein histidine kinase activity
AM393_RS01905	COG0745	RESPONSE REGULATOR receiver
AM393_RS01910	COG0826	peptidase U32
AM393_RS01920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM393_RS01930	COG1070	Carbohydrate kinase
AM393_RS01965	COG1830	Aldolase
AM393_RS01970	COG0351	phosphomethylpyrimidine kinase
AM393_RS01985	COG0583	DNA-binding transcription factor activity
AM393_RS01995	COG2252	PERMEase
AM393_RS02000	COG0583	DNA-binding transcription factor activity
AM393_RS02005	COG5455	response to cobalt ion
AM393_RS02025	COG4807	Protein conserved in bacteria
AM393_RS02035	COG3275	phosphorelay sensor kinase activity
AM393_RS02045	COG1174	glycine betaine transport
AM393_RS02050	COG1125	glycine betaine transport
AM393_RS02055	COG1174	glycine betaine transport
AM393_RS02060	COG1732	Glycine betaine
AM393_RS02065	COG1472	Belongs to the glycosyl hydrolase 3 family
AM393_RS02070	COG0277	FAD linked oxidase domain protein
AM393_RS02080	COG1686	Belongs to the peptidase S11 family
AM393_RS02090	COG0586	Pfam SNARE associated Golgi protein
AM393_RS02095	COG1538	Outer membrane efflux protein
AM393_RS02105	COG2723	6-phospho-beta-galactosidase activity
AM393_RS02120	COG3659	wide pore channel activity
AM393_RS02125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM393_RS02135	COG1346	cytolysis
AM393_RS02150	COG2949	membrane
AM393_RS02160	COG1129	ABC transporter
AM393_RS02180	COG2311	Membrane
AM393_RS02195	COG4771	TonB-dependent receptor
AM393_RS02205	COG0833	amino acid
AM393_RS02210	COG0583	DNA-binding transcription factor activity
AM393_RS02220	COG2855	membrane
AM393_RS02230	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM393_RS02230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM393_RS02230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM393_RS02235	COG1105	Belongs to the carbohydrate kinase PfkB family
AM393_RS02240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS02240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS02250	COG2814	Major facilitator Superfamily
AM393_RS02265	COG1312	Catalyzes the dehydration of D-mannonate
AM393_RS02270	COG0246	Mannitol dehydrogenase
AM393_RS02275	COG0523	cobalamin synthesis protein
AM393_RS02280	COG0671	phosphoesterase, PA-phosphatase related
AM393_RS02285	COG0791	NLP P60 protein
AM393_RS02295	COG4166	transmembrane transport
AM393_RS02300	COG4174	ABC transporter (Permease)
AM393_RS02305	COG4239	(ABC) transporter, permease
AM393_RS02310	COG4172	Belongs to the ABC transporter superfamily
AM393_RS02320	COG2814	Major facilitator Superfamily
AM393_RS02325	COG1187	pseudouridine synthase activity
AM393_RS02330	COG1061	Type III restriction enzyme res subunit
AM393_RS02350	COG0494	nUDIX hydrolase
AM393_RS02355	COG1349	DNA-binding transcription factor activity
AM393_RS02380	COG0582	viral genome integration into host DNA
AM393_RS02430	COG0628	permease
AM393_RS02445	COG0659	secondary active sulfate transmembrane transporter activity
AM393_RS02450	COG2239	Acts as a magnesium transporter
AM393_RS02455	COG4615	Cyclic peptide transporter
AM393_RS02460	COG3145	DNA-N1-methyladenine dioxygenase activity
AM393_RS02465	COG2169	Transcriptional regulator
AM393_RS02465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM393_RS02480	COG0642	Histidine kinase
AM393_RS02480	COG2198	Histidine kinase
AM393_RS02490	COG0784	Response regulator, receiver
AM393_RS02490	COG2205	protein histidine kinase activity
AM393_RS02520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM393_RS02530	COG0584	glycerophosphoryl diester phosphodiesterase
AM393_RS02535	COG2271	Major facilitator Superfamily
AM393_RS02540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM393_RS02550	COG0247	lactate metabolic process
AM393_RS02560	COG2271	Major facilitator Superfamily
AM393_RS02570	COG1414	Transcriptional regulator
AM393_RS02590	COG5464	transposase or invertase
AM393_RS02600	COG0318	PFAM AMP-dependent synthetase and ligase
AM393_RS02625	COG1169	isochorismate synthase
AM393_RS02630	COG2153	protein acetylation
AM393_RS02645	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM393_RS02650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM393_RS02660	COG0839	Belongs to the complex I subunit 6 family
AM393_RS02710	COG0583	DNA-binding transcription factor activity
AM393_RS02715	COG0436	Aminotransferase
AM393_RS02725	COG0490	domain, Protein
AM393_RS02725	COG0471	metal ion transport
AM393_RS02730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM393_RS02750	COG0280	phosphate acetyltransferase
AM393_RS02750	COG0857	belongs to the CobB CobQ family
AM393_RS02755	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM393_RS02760	COG0622	Phosphoesterase
AM393_RS02765	COG0625	glutathione transferase activity
AM393_RS02770	COG0625	glutathione transferase activity
AM393_RS02775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM393_RS02780	COG1090	epimerase
AM393_RS02790	COG4598	ABC transporter
AM393_RS02795	COG4160	amino acid transport
AM393_RS02815	COG0163	prenyltransferase activity
AM393_RS02820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM393_RS02825	COG1286	toxin biosynthetic process
AM393_RS02830	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM393_RS02835	COG0285	dihydrofolate synthase activity
AM393_RS02845	COG0586	Pfam SNARE associated Golgi protein
AM393_RS02855	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM393_RS02875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM393_RS02890	COG3101	peptidyl-lysine hydroxylation
AM393_RS02895	COG0730	response to heat
AM393_RS02920	COG2062	phosphohistidine phosphatase, SixA
AM393_RS02935	COG3691	Protein conserved in bacteria
AM393_RS02945	COG2853	Lipoprotein
AM393_RS02950	COG2116	formate transmembrane transporter activity
AM393_RS02970	COG0583	DNA-binding transcription factor activity
AM393_RS02975	COG0590	tRNA wobble adenosine to inosine editing
AM393_RS02980	COG2807	transmembrane transport
AM393_RS02985	COG0436	Aminotransferase
AM393_RS02995	COG3275	phosphorelay sensor kinase activity
AM393_RS03000	COG3279	Response regulator of the LytR AlgR family
AM393_RS03015	COG3961	Belongs to the TPP enzyme family
AM393_RS03020	COG0667	Aldo Keto reductase
AM393_RS03035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM393_RS03040	COG2199	diguanylate cyclase activity
AM393_RS03040	COG2200	EAL domain
AM393_RS03055	COG3415	Transposase
AM393_RS03060	COG3415	Transposase
AM393_RS03090	COG0583	DNA-binding transcription factor activity
AM393_RS03095	COG0385	Bile acid
AM393_RS03100	COG3530	Putative quorum-sensing-regulated virulence factor
AM393_RS03120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM393_RS03155	COG4319	ketosteroid isomerase
AM393_RS03165	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM393_RS03170	COG4208	sulfate ABC transporter
AM393_RS03175	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM393_RS03180	COG4150	thiosulfate binding
AM393_RS03190	COG2837	iron assimilation
AM393_RS03210	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM393_RS03300	COG4810	utilization protein
AM393_RS03310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM393_RS03315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM393_RS03320	COG5342	invasion associated locus B
AM393_RS03330	COG0493	'glutamate synthase
AM393_RS03330	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM393_RS03340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM393_RS03345	COG1393	Belongs to the ArsC family
AM393_RS03360	COG0400	carboxylic ester hydrolase activity
AM393_RS03365	COG1444	tRNA N-acetyltransferase activity
AM393_RS03370	COG2321	neutral zinc metallopeptidase
AM393_RS03380	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM393_RS03390	COG2716	regulation of RNA biosynthetic process
AM393_RS03395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM393_RS03400	COG0628	permease
AM393_RS03405	COG4783	chaperone-mediated protein folding
AM393_RS03410	COG1393	Belongs to the ArsC family
AM393_RS03425	COG2233	PERMEase
AM393_RS03435	COG2723	6-phospho-beta-galactosidase activity
AM393_RS03450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM393_RS03465	COG2200	EAL domain
AM393_RS03485	COG0641	radical SAM
AM393_RS03490	COG3119	arylsulfatase activity
AM393_RS03500	COG0516	GMP reductase activity
AM393_RS03500	COG0517	IMP dehydrogenase activity
AM393_RS03510	COG1645	bacterial-type flagellum-dependent swarming motility
AM393_RS03530	COG2976	Protein conserved in bacteria
AM393_RS03560	COG4953	penicillin-binding protein 1C
AM393_RS03565	COG2373	Large extracellular alpha-helical protein
AM393_RS03570	COG2897	thiosulfate sulfurtransferase activity
AM393_RS03590	COG2975	iron-sulfur cluster assembly
AM393_RS03595	COG0633	Ferredoxin
AM393_RS03615	COG0822	iron-sulfur transferase activity
AM393_RS03645	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM393_RS03650	COG3683	transport system, periplasmic component
AM393_RS03655	COG3711	transcriptional antiterminator
AM393_RS03660	COG2814	Major facilitator Superfamily
AM393_RS03665	COG2017	converts alpha-aldose to the beta-anomer
AM393_RS03670	COG0477	Major facilitator Superfamily
AM393_RS03670	COG2814	Major facilitator Superfamily
AM393_RS03675	COG0457	Tetratricopeptide repeat
AM393_RS03680	COG1940	carbohydrate kinase activity
AM393_RS03685	COG2259	Doxx family
AM393_RS03700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM393_RS03700	COG1017	nitric oxide dioxygenase activity
AM393_RS03705	COG0347	Belongs to the P(II) protein family
AM393_RS03710	COG2204	response regulator
AM393_RS03715	COG3170	Tfp pilus assembly protein FimV
AM393_RS03720	COG2205	protein histidine kinase activity
AM393_RS03730	COG0047	phosphoribosylformylglycinamidine synthase activity
AM393_RS03730	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM393_RS03745	COG0560	Phosphoserine phosphatase
AM393_RS03750	COG1737	Transcriptional regulator
AM393_RS03755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM393_RS03765	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM393_RS03785	COG0681	Belongs to the peptidase S26 family
AM393_RS03795	COG3086	response to oxidative stress
AM393_RS03800	COG3026	antisigma factor binding
AM393_RS03805	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AM393_RS03815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM393_RS03825	COG0513	Belongs to the DEAD box helicase family
AM393_RS03840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM393_RS03850	COG3118	belongs to the thioredoxin family
AM393_RS03855	COG3148	PFAM DTW domain containing protein
AM393_RS03865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM393_RS03870	COG5544	Lipoprotein
AM393_RS03875	COG0477	Major facilitator Superfamily
AM393_RS03900	COG0542	response to heat
AM393_RS03915	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM393_RS03925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM393_RS03930	COG1605	Chorismate mutase
AM393_RS03930	COG0077	Prephenate dehydratase
AM393_RS03940	COG1605	Chorismate mutase
AM393_RS03940	COG0287	Prephenate dehydrogenase
AM393_RS03945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM393_RS03955	COG2199	diguanylate cyclase activity
AM393_RS03960	COG2885	chlorophyll binding
AM393_RS03995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM393_RS04000	COG4137	Cytochrome C assembly protein
AM393_RS04005	COG4536	flavin adenine dinucleotide binding
AM393_RS04025	COG0497	DNA recombination
AM393_RS04040	COG2867	negative regulation of translational initiation
AM393_RS04070	COG2207	Transcriptional regulator
AM393_RS04070	COG3708	Transcriptional regulator
AM393_RS04075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM393_RS04110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM393_RS04120	COG0235	Class ii aldolase
AM393_RS04130	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS04145	COG2197	response regulator
AM393_RS04150	COG3539	Fimbrial protein
AM393_RS04160	COG3188	usher protein
AM393_RS04180	COG3121	Chaperone
AM393_RS04185	COG3539	Fimbrial protein
AM393_RS04195	COG3284	Transcriptional regulator
AM393_RS04200	COG0583	DNA-binding transcription factor activity
AM393_RS04210	COG0640	Transcriptional regulator
AM393_RS04215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM393_RS04230	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM393_RS04255	COG4575	ribosome binding
AM393_RS04260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM393_RS04265	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM393_RS04270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM393_RS04280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM393_RS04295	COG4176	ABC-type proline glycine betaine transport system permease component
AM393_RS04305	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM393_RS04315	COG1846	Transcriptional regulator
AM393_RS04320	COG1566	PFAM secretion protein HlyD family protein
AM393_RS04325	COG2814	Major facilitator Superfamily
AM393_RS04330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM393_RS04350	COG1238	metal cluster binding
AM393_RS04355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM393_RS04360	COG2823	Periplasmic or secreted lipoprotein
AM393_RS04390	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM393_RS04415	COG1546	Belongs to the CinA family
AM393_RS04425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM393_RS04430	COG1121	(ABC) transporter
AM393_RS04440	COG2951	lytic endotransglycosylase activity
AM393_RS04445	COG3730	PTS system glucitol sorbitol-specific
AM393_RS04450	COG3732	PTS system glucitol sorbitol-specific
AM393_RS04460	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS04465	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS04470	COG1349	DNA-binding transcription factor activity
AM393_RS04500	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AM393_RS04505	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM393_RS04510	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM393_RS04515	COG1609	Transcriptional regulator
AM393_RS04520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM393_RS04520	COG1263	PTS System
AM393_RS04525	COG2723	6-phospho-beta-galactosidase activity
AM393_RS04535	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM393_RS04545	COG3260	NADH ubiquinone oxidoreductase 20
AM393_RS04550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM393_RS04555	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM393_RS04555	COG3261	NADH dehydrogenase
AM393_RS04560	COG0650	Formate hydrogenlyase subunit 4
AM393_RS04565	COG0651	ATP synthesis coupled electron transport
AM393_RS04570	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM393_RS04590	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM393_RS04595	COG0298	carbon dioxide binding
AM393_RS04600	COG0409	Hydrogenase expression formation protein
AM393_RS04605	COG0309	Hydrogenase expression formation protein (HypE)
AM393_RS04615	COG2723	6-phospho-beta-galactosidase activity
AM393_RS04625	COG4580	involved in the transport of maltose and maltodextrins
AM393_RS04635	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS04640	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS04645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS04650	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM393_RS04655	COG1940	carbohydrate kinase activity
AM393_RS04660	COG1609	Transcriptional regulator
AM393_RS04665	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM393_RS04670	COG1121	(ABC) transporter
AM393_RS04675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM393_RS04680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM393_RS04695	COG0679	Auxin Efflux Carrier
AM393_RS04715	COG3720	iron ion transport
AM393_RS04720	COG4558	Periplasmic binding protein
AM393_RS04725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM393_RS04765	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM393_RS04770	COG0163	prenyltransferase activity
AM393_RS04795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM393_RS04800	COG1388	LysM domain
AM393_RS04800	COG4942	peptidase
AM393_RS04860	COG2234	aminopeptidase activity
AM393_RS04880	COG0720	synthase
AM393_RS04885	COG0602	queuosine metabolic process
AM393_RS04905	COG3956	TIGRFAM MazG family protein
AM393_RS04910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM393_RS04920	COG2205	protein histidine kinase activity
AM393_RS04920	COG3850	Histidine kinase
AM393_RS04920	COG3437	response regulator, receiver
AM393_RS04920	COG4999	Histidine kinase
AM393_RS04925	COG1929	Belongs to the glycerate kinase type-1 family
AM393_RS04930	COG4948	Mandelate Racemase Muconate Lactonizing
AM393_RS04935	COG4948	Mandelate Racemase Muconate Lactonizing
AM393_RS04940	COG2271	Major facilitator Superfamily
AM393_RS04945	COG0716	FMN binding
AM393_RS04950	COG0564	pseudouridine synthase activity
AM393_RS04955	COG3098	single-species biofilm formation
AM393_RS04970	COG1611	Belongs to the LOG family
AM393_RS04975	COG0814	amino acid
AM393_RS04980	COG1760	l-serine dehydratase
AM393_RS04985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM393_RS04995	COG0477	Major facilitator Superfamily
AM393_RS05005	COG1464	Belongs to the NlpA lipoprotein family
AM393_RS05010	COG2011	ABC-type metal ion transport system permease component
AM393_RS05015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM393_RS05030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM393_RS05045	COG1454	alcohol dehydrogenase
AM393_RS05050	COG0235	Class ii aldolase
AM393_RS05055	COG0738	Major facilitator superfamily
AM393_RS05075	COG1349	DNA-binding transcription factor activity
AM393_RS05085	COG2363	Small membrane protein
AM393_RS05090	COG0583	DNA-binding transcription factor activity
AM393_RS05100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM393_RS05105	COG2166	iron-sulfur cluster assembly
AM393_RS05110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM393_RS05115	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM393_RS05280	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM393_RS05310	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS05310	COG1454	alcohol dehydrogenase
AM393_RS05315	COG4656	Part of a membrane complex involved in electron transport
AM393_RS05345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM393_RS05350	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM393_RS05355	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM393_RS05355	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM393_RS05365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM393_RS05370	COG1074	ATP-dependent DNA helicase activity
AM393_RS05375	COG1025	Belongs to the peptidase M16 family
AM393_RS05380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM393_RS05385	COG4967	type IV pilus modification protein PilV
AM393_RS05395	COG4795	General secretion pathway protein
AM393_RS05400	COG2165	general secretion pathway protein
AM393_RS05430	COG0861	Integral membrane protein TerC family
AM393_RS05440	COG0667	Aldo Keto reductase
AM393_RS05465	COG1609	Transcriptional regulator
AM393_RS05475	COG2186	Transcriptional regulator
AM393_RS05480	COG2723	6-phospho-beta-galactosidase activity
AM393_RS05485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS05490	COG1609	Transcriptional regulator
AM393_RS05500	COG0583	DNA-binding transcription factor activity
AM393_RS05505	COG1794	racemase activity, acting on amino acids and derivatives
AM393_RS05510	COG1917	Cupin 2, conserved barrel domain protein
AM393_RS05515	COG1175	transmembrane transport
AM393_RS05520	COG0395	ABC-type sugar transport system, permease component
AM393_RS05525	COG3842	ATPase activity
AM393_RS05555	COG2814	Major facilitator Superfamily
AM393_RS05560	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS05565	COG0823	Involved in the tonB-independent uptake of proteins
AM393_RS05575	COG0183	Belongs to the thiolase family
AM393_RS05590	COG0814	amino acid
AM393_RS05595	COG0667	Aldo Keto reductase
AM393_RS05645	COG0697	spore germination
AM393_RS05650	COG1846	Transcriptional regulator
AM393_RS05655	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM393_RS05670	COG0582	viral genome integration into host DNA
AM393_RS05675	COG4974	Belongs to the 'phage' integrase family
AM393_RS05685	COG3539	Fimbrial protein
AM393_RS05690	COG3121	Chaperone
AM393_RS05695	COG3188	usher protein
AM393_RS05700	COG3539	Fimbrial protein
AM393_RS05705	COG3539	Fimbrial protein
AM393_RS05710	COG3539	Fimbrial protein
AM393_RS05720	COG2388	GCN5-related N-acetyl-transferase
AM393_RS05725	COG3592	Divergent 4Fe-4S mono-cluster
AM393_RS05740	COG1289	transmembrane transporter activity
AM393_RS05745	COG1538	Outer membrane efflux protein
AM393_RS05760	COG1393	Belongs to the ArsC family
AM393_RS05765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM393_RS05800	COG0667	Aldo Keto reductase
AM393_RS05815	COG2814	Major facilitator Superfamily
AM393_RS05825	COG4942	peptidase
AM393_RS05850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM393_RS05860	COG4974	Belongs to the 'phage' integrase family
AM393_RS05865	COG0716	FMN binding
AM393_RS05875	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM393_RS05885	COG1272	protein, Hemolysin III
AM393_RS05895	COG1737	Transcriptional regulator
AM393_RS05900	COG2723	6-phospho-beta-galactosidase activity
AM393_RS05920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM393_RS05925	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS05945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM393_RS05950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM393_RS05955	COG0006	proline dipeptidase activity
AM393_RS05975	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM393_RS05980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM393_RS05995	COG2968	Membrane
AM393_RS06005	COG0668	transmembrane transport
AM393_RS06010	COG0191	fructose-bisphosphate aldolase activity
AM393_RS06025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM393_RS06030	COG0501	Belongs to the peptidase M48B family
AM393_RS06050	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AM393_RS06055	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS06085	COG1414	Transcriptional regulator
AM393_RS06090	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS06105	COG2146	nitrite reductase [NAD(P)H] activity
AM393_RS06150	COG2814	Major facilitator Superfamily
AM393_RS06160	COG2356	endonuclease I
AM393_RS06165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM393_RS06170	COG0189	ligase activity
AM393_RS06190	COG2805	Type II/IV secretion system protein
AM393_RS06195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM393_RS06200	COG0762	integral membrane protein
AM393_RS06215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM393_RS06225	COG3171	Protein conserved in bacteria
AM393_RS06235	COG1194	a g-specific adenine glycosylase
AM393_RS06250	COG2211	Major facilitator Superfamily
AM393_RS06255	COG1982	Orn Lys Arg decarboxylase major
AM393_RS06265	COG1811	Na channel or pump
AM393_RS06275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM393_RS06335	COG3423	Transcriptional regulator
AM393_RS06340	COG1278	Cold shock
AM393_RS06350	COG3423	Transcriptional regulator
AM393_RS06610	COG0626	cystathionine gamma-synthase activity
AM393_RS06615	COG0583	DNA-binding transcription factor activity
AM393_RS06635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM393_RS06640	COG0754	glutathionylspermidine amidase activity
AM393_RS06650	COG0625	glutathione transferase activity
AM393_RS06675	COG2211	Major facilitator Superfamily
AM393_RS06680	COG0848	biopolymer transport protein
AM393_RS06695	COG0626	cystathionine gamma-synthase activity
AM393_RS06700	COG0586	Pfam SNARE associated Golgi protein
AM393_RS06705	COG2207	Transcriptional regulator
AM393_RS06710	COG1979	alcohol dehydrogenase
AM393_RS06715	COG0656	L-ascorbic acid biosynthetic process
AM393_RS06725	COG1032	radical SAM domain protein
AM393_RS06730	COG2132	Multicopper oxidase
AM393_RS06735	COG0204	Acyl-transferase
AM393_RS06740	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM393_RS06745	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM393_RS06750	COG3111	PFAM Bacterial OB fold (BOF) protein
AM393_RS06760	COG0642	Histidine kinase
AM393_RS06765	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM393_RS06770	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM393_RS06780	COG3150	esterase
AM393_RS06785	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM393_RS06790	COG3151	Protein conserved in bacteria
AM393_RS06795	COG0494	nUDIX hydrolase
AM393_RS06810	COG0754	glutathionylspermidine amidase activity
AM393_RS06815	COG3384	dioxygenase
AM393_RS06830	COG2960	long-chain fatty acid transporting porin activity
AM393_RS06850	COG3025	triphosphatase activity
AM393_RS06855	COG4991	sh3 domain protein
AM393_RS06870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM393_RS06935	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM393_RS06940	COG0358	DNA primase activity
AM393_RS06945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM393_RS06970	COG2197	response regulator
AM393_RS06975	COG2205	protein histidine kinase activity
AM393_RS06975	COG2198	Histidine kinase
AM393_RS06975	COG0784	Response regulator, receiver
AM393_RS06975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM393_RS06985	COG3247	response to pH
AM393_RS07065	COG2376	Dihydroxyacetone kinase
AM393_RS07070	COG1461	Dihydroxyacetone kinase
AM393_RS07085	COG2375	cellular response to nickel ion
AM393_RS07090	COG1695	Transcriptional regulator
AM393_RS07145	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM393_RS07145	COG1902	pentaerythritol trinitrate reductase activity
AM393_RS07165	COG1451	nucleotide metabolic process
AM393_RS07170	COG0673	inositol 2-dehydrogenase activity
AM393_RS07175	COG0861	Integral membrane protein TerC family
AM393_RS07190	COG2721	sulfolactate sulfo-lyase activity
AM393_RS07200	COG2271	Major facilitator Superfamily
AM393_RS07205	COG2186	Transcriptional regulator
AM393_RS07210	COG0586	Pfam SNARE associated Golgi protein
AM393_RS07220	COG1422	Protein of unknown function (DUF1090)
AM393_RS07225	COG4575	ribosome binding
AM393_RS07230	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM393_RS07240	COG2259	Doxx family
AM393_RS07245	COG0435	Glutathione S-transferase
AM393_RS07250	COG3152	Membrane
AM393_RS07255	COG0583	DNA-binding transcription factor activity
AM393_RS07260	COG1741	Belongs to the pirin family
AM393_RS07280	COG1929	Belongs to the glycerate kinase type-1 family
AM393_RS07285	COG2084	Dehydrogenase
AM393_RS07295	COG2271	Major facilitator Superfamily
AM393_RS07300	COG2721	sulfolactate sulfo-lyase activity
AM393_RS07305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM393_RS07310	COG1349	DNA-binding transcription factor activity
AM393_RS07320	COG1105	Belongs to the carbohydrate kinase PfkB family
AM393_RS07325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS07325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM393_RS07325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM393_RS07330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS07330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS07340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS07345	COG3414	Phosphotransferase system galactitol-specific IIB component
AM393_RS07350	COG3775	system Galactitol-specific IIC component
AM393_RS07355	COG1063	alcohol dehydrogenase
AM393_RS07370	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM393_RS07390	COG2823	Periplasmic or secreted lipoprotein
AM393_RS07395	COG0701	Predicted permease
AM393_RS07400	COG0702	epimerase
AM393_RS07405	COG0693	protein deglycase activity
AM393_RS07420	COG3153	acetyltransferase
AM393_RS07425	COG3154	lipid carrier protein
AM393_RS07430	COG0826	peptidase U32
AM393_RS07435	COG0826	peptidase U32
AM393_RS07440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM393_RS07445	COG0814	amino acid
AM393_RS07495	COG0195	Participates in both transcription termination and antitermination
AM393_RS07535	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM393_RS07545	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM393_RS07550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM393_RS07565	COG1534	Rna-binding protein
AM393_RS07575	COG2027	D-alanyl-D-alanine carboxypeptidase
AM393_RS07585	COG0697	spore germination
AM393_RS07600	COG0142	geranyltranstransferase activity
AM393_RS07605	COG3423	Transcriptional regulator
AM393_RS07615	COG5007	Belongs to the BolA IbaG family
AM393_RS07620	COG3113	response to antibiotic
AM393_RS07625	COG2854	intermembrane phospholipid transfer
AM393_RS07630	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM393_RS07635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM393_RS07640	COG1127	ABC transporter
AM393_RS07650	COG0530	calcium, potassium:sodium antiporter activity
AM393_RS07660	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM393_RS07665	COG3117	lipopolysaccharide transmembrane transporter activity
AM393_RS07670	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM393_RS07675	COG1137	ATPase activity
AM393_RS07680	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM393_RS07685	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM393_RS07690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS07700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS07705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM393_RS07710	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM393_RS07715	COG2198	Histidine kinase
AM393_RS07715	COG5002	protein histidine kinase activity
AM393_RS07715	COG0784	Response regulator, receiver
AM393_RS07720	COG1312	Catalyzes the dehydration of D-mannonate
AM393_RS07725	COG1063	alcohol dehydrogenase
AM393_RS07730	COG2271	Major facilitator Superfamily
AM393_RS07735	COG1242	4 iron, 4 sulfur cluster binding
AM393_RS07745	COG0069	glutamate synthase activity
AM393_RS07745	COG0067	glutamate synthase
AM393_RS07745	COG0070	glutamate synthase
AM393_RS07750	COG0493	'glutamate synthase
AM393_RS07760	COG2969	positive regulation of protein catabolic process
AM393_RS07765	COG0625	glutathione transferase activity
AM393_RS07785	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM393_RS07790	COG3105	Protein conserved in bacteria
AM393_RS07795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM393_RS07800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM393_RS07825	COG2732	(Barnase) inhibitor
AM393_RS07830	COG1289	transmembrane transporter activity
AM393_RS07845	COG0583	DNA-binding transcription factor activity
AM393_RS07850	COG0312	modulator of DNA gyrase
AM393_RS07855	COG3164	Protein of unknown function
AM393_RS07860	COG1530	ribonuclease E activity
AM393_RS07870	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM393_RS07875	COG1792	Involved in formation and maintenance of cell shape
AM393_RS07880	COG1077	Cell shape determining protein MreB Mrl
AM393_RS07890	COG2199	diguanylate cyclase activity
AM393_RS07890	COG2200	EAL domain
AM393_RS07920	COG0511	ligase activity, forming carbon-carbon bonds
AM393_RS07925	COG0439	Biotin carboxylase
AM393_RS07930	COG3924	membrane
AM393_RS07935	COG4145	pantothenate transmembrane transporter activity
AM393_RS07965	COG1802	Transcriptional regulator
AM393_RS07965	COG4626	Terminase
AM393_RS08055	COG3561	AntA/AntB antirepressor
AM393_RS08070	COG0582	viral genome integration into host DNA
AM393_RS08075	COG1309	transcriptional regulator
AM393_RS08080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM393_RS08085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM393_RS08120	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM393_RS08140	COG0551	DNA topoisomerase type I activity
AM393_RS08150	COG0758	DNA mediated transformation
AM393_RS08180	COG3036	rescue of stalled ribosome
AM393_RS08185	COG0789	Transcriptional regulator
AM393_RS08200	COG0202	RNA polymerase activity
AM393_RS08225	COG0201	protein transport
AM393_RS08290	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM393_RS08305	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM393_RS08330	COG0051	transcription antitermination factor activity, RNA binding
AM393_RS08390	COG2964	Protein conserved in bacteria
AM393_RS08395	COG0545	Peptidyl-prolyl cis-trans isomerase
AM393_RS08405	COG1047	Peptidyl-prolyl cis-trans
AM393_RS08410	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM393_RS08425	COG0488	(ABC) transporter
AM393_RS08435	COG0429	hydrolase of the alpha beta-hydrolase fold
AM393_RS08445	COG3954	Phosphoribulokinase
AM393_RS08450	COG1765	OsmC-like protein
AM393_RS08465	COG1289	transmembrane transporter activity
AM393_RS08470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM393_RS08495	COG0738	Major facilitator superfamily
AM393_RS08500	COG0402	S-adenosylhomocysteine deaminase activity
AM393_RS08505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM393_RS08530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM393_RS08535	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AM393_RS08540	COG3266	domain, Protein
AM393_RS08560	COG4796	Type ii and iii secretion system protein
AM393_RS08585	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM393_RS08590	COG0494	nUDIX hydrolase
AM393_RS08600	COG1011	Hydrolase
AM393_RS08605	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM393_RS08630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM393_RS08635	COG2183	response to ionizing radiation
AM393_RS08640	COG1918	ferrous iron import across plasma membrane
AM393_RS08665	COG1040	competence protein
AM393_RS08675	COG2610	gluconate transmembrane transporter activity
AM393_RS08680	COG1640	4-alpha-glucanotransferase
AM393_RS08685	COG0058	SHG alpha-glucan phosphorylase activity
AM393_RS08700	COG1349	DNA-binding transcription factor activity
AM393_RS08715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM393_RS08730	COG0058	SHG alpha-glucan phosphorylase activity
AM393_RS08755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM393_RS08765	COG2610	gluconate transmembrane transporter activity
AM393_RS08770	COG3265	gluconokinase activity
AM393_RS08775	COG1609	Transcriptional regulator
AM393_RS08780	COG1741	Belongs to the pirin family
AM393_RS08785	COG0673	inositol 2-dehydrogenase activity
AM393_RS08800	COG1247	-acetyltransferase
AM393_RS08805	COG0405	Gamma-glutamyltransferase
AM393_RS08815	COG0584	glycerophosphoryl diester phosphodiesterase
AM393_RS08865	COG0559	Belongs to the binding-protein-dependent transport system permease family
AM393_RS08870	COG0683	leucine binding
AM393_RS08880	COG0683	leucine binding
AM393_RS08890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM393_RS08905	COG2177	Part of the ABC transporter FtsEX involved in
AM393_RS08910	COG2884	Cell division ATP-binding protein ftsE
AM393_RS08915	COG0552	protein localization to endoplasmic reticulum
AM393_RS08920	COG0742	ribosomal rna small subunit methyltransferase
AM393_RS08925	COG3776	membrane
AM393_RS08935	COG3714	YhhN family
AM393_RS08950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM393_RS08960	COG0477	Major facilitator Superfamily
AM393_RS08965	COG0628	permease
AM393_RS09005	COG3479	Phenolic acid decarboxylase
AM393_RS09015	COG0747	negative chemotaxis
AM393_RS09020	COG0601	transmembrane transport
AM393_RS09025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM393_RS09035	COG1124	(ABC) transporter
AM393_RS09045	COG2239	Acts as a magnesium transporter
AM393_RS09050	COG2081	HI0933 family
AM393_RS09055	COG0306	phosphate transporter
AM393_RS09065	COG0589	response to stress
AM393_RS09085	COG0671	phosphoesterase, PA-phosphatase related
AM393_RS09090	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM393_RS09095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM393_RS09105	COG1454	alcohol dehydrogenase
AM393_RS09115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM393_RS09120	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS09125	COG0583	DNA-binding transcription factor activity
AM393_RS09130	COG1295	ribonuclease BN
AM393_RS09135	COG0477	Major facilitator Superfamily
AM393_RS09140	COG2982	Protein involved in outer membrane biogenesis
AM393_RS09155	COG0612	Peptidase, M16
AM393_RS09165	COG2200	EAL domain
AM393_RS09165	COG2199	diguanylate cyclase activity
AM393_RS09170	COG3118	belongs to the thioredoxin family
AM393_RS09170	COG0457	Tetratricopeptide repeat
AM393_RS09175	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM393_RS09180	COG1215	transferase activity, transferring glycosyl groups
AM393_RS09210	COG2194	sulfuric ester hydrolase activity
AM393_RS09225	COG0457	Tetratricopeptide repeat
AM393_RS09230	COG1215	transferase activity, transferring glycosyl groups
AM393_RS09255	COG4608	Belongs to the ABC transporter superfamily
AM393_RS09260	COG0444	Belongs to the ABC transporter superfamily
AM393_RS09265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM393_RS09270	COG0601	transmembrane transport
AM393_RS09275	COG0747	negative chemotaxis
AM393_RS09310	COG2223	nitrite transmembrane transporter activity
AM393_RS09315	COG5571	outer membrane autotransporter
AM393_RS09320	COG2818	Glycosylase
AM393_RS09325	COG0456	acetyltransferase
AM393_RS09330	COG0243	molybdopterin cofactor binding
AM393_RS09335	COG2885	chlorophyll binding
AM393_RS09340	COG1609	Transcriptional regulator
AM393_RS09350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM393_RS09370	COG2814	Major facilitator Superfamily
AM393_RS09375	COG2944	sequence-specific DNA binding
AM393_RS09380	COG1278	Cold shock
AM393_RS09415	COG3274	enterobacterial common antigen metabolic process
AM393_RS09420	COG4682	membrane
AM393_RS09425	COG4682	membrane
AM393_RS09445	COG4213	ABC transporter substrate-binding protein
AM393_RS09455	COG4214	carbohydrate transport
AM393_RS09460	COG2207	Transcriptional regulator
AM393_RS09460	COG1609	Transcriptional regulator
AM393_RS09465	COG2992	FlgJ-related protein
AM393_RS09475	COG0366	Alpha amylase catalytic
AM393_RS09480	COG3977	Valine--pyruvate aminotransferase
AM393_RS09485	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM393_RS09490	COG1414	Transcriptional regulator
AM393_RS09495	COG3276	selenocysteine insertion sequence binding
AM393_RS09505	COG0625	glutathione transferase activity
AM393_RS09510	COG1566	PFAM secretion protein HlyD family protein
AM393_RS09530	COG3722	fumarate hydratase activity
AM393_RS09550	COG2186	Transcriptional regulator
AM393_RS09560	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM393_RS09580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM393_RS09585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM393_RS09595	COG4942	peptidase
AM393_RS09600	COG2861	carbohydrate metabolic process
AM393_RS09605	COG0463	Glycosyl transferase, family 2
AM393_RS09615	COG0156	8-amino-7-oxononanoate synthase activity
AM393_RS09630	COG0859	PFAM glycosyl transferase family 9
AM393_RS09655	COG0859	PFAM glycosyl transferase family 9
AM393_RS09665	COG0438	transferase activity, transferring glycosyl groups
AM393_RS09670	COG1216	Glycosyl transferase, family 2
AM393_RS09675	COG1519	Transferase
AM393_RS09710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM393_RS09735	COG0842	Transport permease protein
AM393_RS09740	COG1131	(ABC) transporter
AM393_RS09760	COG1561	YicC-like family, N-terminal region
AM393_RS09765	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AM393_RS09770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM393_RS09770	COG2169	Transcriptional regulator
AM393_RS09780	COG2860	membrane
AM393_RS09800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM393_RS09805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM393_RS09810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM393_RS09815	COG1494	fructose-1,6-bisphosphatase
AM393_RS09825	COG3152	Membrane
AM393_RS09850	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM393_RS09870	COG0786	glutamate:sodium symporter activity
AM393_RS09875	COG2233	PERMEase
AM393_RS09880	COG2982	Protein involved in outer membrane biogenesis
AM393_RS09885	COG1263	PTS System
AM393_RS09885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM393_RS09890	COG1486	melibiose metabolic process
AM393_RS09900	COG1501	Belongs to the glycosyl hydrolase 31 family
AM393_RS09905	COG2211	Major facilitator Superfamily
AM393_RS09940	COG1064	alcohol dehydrogenase
AM393_RS09950	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AM393_RS09965	COG1464	Belongs to the NlpA lipoprotein family
AM393_RS09990	COG0583	DNA-binding transcription factor activity
AM393_RS10025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM393_RS10035	COG2814	Major facilitator Superfamily
AM393_RS10045	COG1263	PTS System
AM393_RS10045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM393_RS10050	COG0697	spore germination
AM393_RS10065	COG2828	Protein conserved in bacteria
AM393_RS10070	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM393_RS10075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AM393_RS10080	COG0583	DNA-binding transcription factor activity
AM393_RS10085	COG3384	dioxygenase
AM393_RS10095	COG1609	Transcriptional regulator
AM393_RS10105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS10105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS10110	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM393_RS10115	COG4580	involved in the transport of maltose and maltodextrins
AM393_RS10140	COG2188	Transcriptional regulator
AM393_RS10185	COG2271	Major facilitator Superfamily
AM393_RS10195	COG2197	response regulator
AM393_RS10200	COG0440	acetolactate synthase activity
AM393_RS10205	COG0028	Belongs to the TPP enzyme family
AM393_RS10230	COG2814	Major facilitator Superfamily
AM393_RS10235	COG0583	DNA-binding transcription factor activity
AM393_RS10240	COG2610	gluconate transmembrane transporter activity
AM393_RS10260	COG2149	membrane
AM393_RS10275	COG2188	Transcriptional regulator
AM393_RS10285	COG3645	SOS response
AM393_RS10300	COG5645	(Lipo)protein
AM393_RS10305	COG0823	Involved in the tonB-independent uptake of proteins
AM393_RS10310	COG2271	Major facilitator Superfamily
AM393_RS10320	COG0800	Aldolase
AM393_RS10325	COG3734	2-keto-3-deoxy-galactonokinase
AM393_RS10330	COG2186	Transcriptional regulator
AM393_RS10345	COG0561	phosphatase activity
AM393_RS10350	COG0187	DNA topoisomerase II activity
AM393_RS10385	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM393_RS10415	COG2091	lysine biosynthetic process via aminoadipic acid
AM393_RS10420	COG0431	NADPH-dependent FMN reductase
AM393_RS10425	COG2252	PERMEase
AM393_RS10435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM393_RS10440	COG0363	glucosamine-6-phosphate deaminase activity
AM393_RS10445	COG2382	esterase
AM393_RS10460	COG0704	Plays a role in the regulation of phosphate uptake
AM393_RS10465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM393_RS10470	COG0581	inorganic phosphate transmembrane transporter activity
AM393_RS10475	COG0573	inorganic phosphate transmembrane transporter activity
AM393_RS10480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM393_RS10485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM393_RS10535	COG3312	ion transport
AM393_RS10550	COG0716	FMN binding
AM393_RS10555	COG1522	sequence-specific DNA binding
AM393_RS10585	COG1129	ABC transporter
AM393_RS10590	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS10600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM393_RS10605	COG1609	Transcriptional regulator
AM393_RS10610	COG0477	Major facilitator Superfamily
AM393_RS10615	COG2186	Transcriptional regulator
AM393_RS10645	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM393_RS10655	COG3084	Protein conserved in bacteria
AM393_RS10660	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM393_RS10670	COG0204	Acyl-transferase
AM393_RS10695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM393_RS10710	COG3852	Histidine kinase
AM393_RS10730	COG1011	Hydrolase
AM393_RS10745	COG0456	acetyltransferase
AM393_RS10750	COG0657	acetylesterase activity
AM393_RS10755	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM393_RS10770	COG2864	formate dehydrogenase
AM393_RS10775	COG0437	4 iron, 4 sulfur cluster binding
AM393_RS10800	COG0205	6-phosphofructokinase activity
AM393_RS10860	COG2211	Major facilitator Superfamily
AM393_RS10870	COG1454	alcohol dehydrogenase
AM393_RS10875	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS10880	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS10885	COG1129	ABC transporter
AM393_RS10930	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM393_RS10935	COG2258	MOSC domain
AM393_RS10940	COG2205	protein histidine kinase activity
AM393_RS10945	COG0745	RESPONSE REGULATOR receiver
AM393_RS10950	COG3678	ATP-independent chaperone mediated protein folding
AM393_RS10970	COG1575	Belongs to the MenA family. Type 1 subfamily
AM393_RS10985	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM393_RS10990	COG1609	Transcriptional regulator
AM393_RS10995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM393_RS11010	COG0626	cystathionine gamma-synthase activity
AM393_RS11015	COG0460	homoserine dehydrogenase
AM393_RS11015	COG0527	aspartate kinase activity
AM393_RS11025	COG0737	Belongs to the 5'-nucleotidase family
AM393_RS11035	COG0583	DNA-binding transcription factor activity
AM393_RS11045	COG0697	spore germination
AM393_RS11050	COG0371	Dehydrogenase
AM393_RS11060	COG2207	Transcriptional regulator
AM393_RS11065	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM393_RS11080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM393_RS11105	COG0583	DNA-binding transcription factor activity
AM393_RS11180	COG3085	chromosome segregation
AM393_RS11200	COG3978	acetolactate synthase activity
AM393_RS11215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM393_RS11220	COG0583	DNA-binding transcription factor activity
AM393_RS11230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM393_RS11235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM393_RS11245	COG1811	Na channel or pump
AM393_RS11275	COG3118	belongs to the thioredoxin family
AM393_RS11285	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM393_RS11290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM393_RS11300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM393_RS11305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM393_RS11310	COG1088	dTDP-glucose 4,6-dehydratase activity
AM393_RS11315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM393_RS11320	COG0456	acetyltransferase
AM393_RS11325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM393_RS11330	COG2244	polysaccharide biosynthetic process
AM393_RS11375	COG3071	HemY protein
AM393_RS11380	COG2959	enzyme of heme biosynthesis
AM393_RS11395	COG3072	Adenylate cyclase
AM393_RS11425	COG1011	Hydrolase
AM393_RS11430	COG0210	DNA helicase
AM393_RS11465	COG1280	lysine exporter protein (LysE YggA)
AM393_RS11475	COG1280	lysine exporter protein (LysE YggA)
AM393_RS11480	COG2267	carboxylic ester hydrolase activity
AM393_RS11485	COG0561	phosphatase activity
AM393_RS11490	COG0697	spore germination
AM393_RS11495	COG0583	DNA-binding transcription factor activity
AM393_RS11525	COG3165	ubiquinone biosynthetic process from chorismate
AM393_RS11545	COG0805	protein transport
AM393_RS11590	COG1739	Uncharacterized protein family UPF0029
AM393_RS11600	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AM393_RS11635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM393_RS11685	COG0250	Participates in transcription elongation, termination and antitermination
AM393_RS11725	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM393_RS11730	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM393_RS11740	COG3706	GGDEF domain
AM393_RS11760	COG2104	thiamine diphosphate biosynthetic process
AM393_RS11765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM393_RS11780	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AM393_RS11815	COG3678	ATP-independent chaperone mediated protein folding
AM393_RS11820	COG4191	Histidine kinase
AM393_RS11830	COG0151	Belongs to the GarS family
AM393_RS11865	COG0456	acetyltransferase
AM393_RS11875	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM393_RS11905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM393_RS11960	COG0527	aspartate kinase activity
AM393_RS11975	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM393_RS11985	COG0251	oxidation-reduction process
AM393_RS12060	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM393_RS12070	COG0534	Mate efflux family protein
AM393_RS12075	COG3237	CsbD-like
AM393_RS12080	COG0735	belongs to the Fur family
AM393_RS12090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM393_RS12105	COG0305	Participates in initiation and elongation during chromosome replication
AM393_RS12110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM393_RS12125	COG0432	Pfam Uncharacterised protein family UPF0047
AM393_RS12130	COG2315	Protein conserved in bacteria
AM393_RS12145	COG0741	lytic transglycosylase activity
AM393_RS12150	COG4771	TonB-dependent receptor
AM393_RS12170	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM393_RS12185	COG0483	inositol monophosphate 1-phosphatase activity
AM393_RS12190	COG1609	Transcriptional regulator
AM393_RS12195	COG1234	tRNA 3'-trailer cleavage
AM393_RS12230	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM393_RS12240	COG0789	Transcriptional regulator
AM393_RS12245	COG0625	glutathione transferase activity
AM393_RS12255	COG2252	PERMEase
AM393_RS12260	COG0025	NhaP-type Na H and K H
AM393_RS12265	COG0583	DNA-binding transcription factor activity
AM393_RS12270	COG1380	Effector of murein hydrolase LrgA
AM393_RS12275	COG1346	cytolysis
AM393_RS12280	COG3539	Fimbrial protein
AM393_RS12310	COG3162	membrane
AM393_RS12320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM393_RS12330	COG1301	dicarboxylic acid transport
AM393_RS12335	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AM393_RS12370	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS12375	COG1129	ABC transporter
AM393_RS12380	COG0784	Response regulator, receiver
AM393_RS12380	COG4191	Histidine kinase
AM393_RS12390	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM393_RS12400	COG3454	Phosphonate metabolism
AM393_RS12405	COG4778	phosphonate C-P lyase system protein PhnL
AM393_RS12410	COG4107	phosphonate C-P lyase system protein PhnK
AM393_RS12415	COG3627	carbon phosphorus lyase activity
AM393_RS12420	COG3626	phosphonate metabolism
AM393_RS12425	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM393_RS12430	COG3624	Phosphonate C-P lyase system protein PhnG
AM393_RS12435	COG2188	Transcriptional regulator
AM393_RS12440	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AM393_RS12445	COG2824	Alkylphosphonate utilization operon protein PhnA
AM393_RS12460	COG2169	Transcriptional regulator
AM393_RS12470	COG1486	melibiose metabolic process
AM393_RS12505	COG0861	Integral membrane protein TerC family
AM393_RS12525	COG1215	transferase activity, transferring glycosyl groups
AM393_RS12530	COG0726	polysaccharide deacetylase
AM393_RS12530	COG1649	PFAM Uncharacterised BCR, COG1649
AM393_RS12535	COG0457	Tetratricopeptide repeat
AM393_RS12560	COG1309	transcriptional regulator
AM393_RS12575	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM393_RS12580	COG1027	Aspartate ammonia-lyase
AM393_RS12590	COG3030	protein affecting phage T7 exclusion by the F plasmid
AM393_RS12595	COG0531	amino acid
AM393_RS12665	COG1509	lysine 2,3-aminomutase activity
AM393_RS12680	COG5510	response to toxic substance
AM393_RS12685	COG2076	Multidrug Resistance protein
AM393_RS12705	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM393_RS12710	COG1053	succinate dehydrogenase
AM393_RS12725	COG1511	domain protein
AM393_RS12725	COG3264	Mechanosensitive ion channel
AM393_RS12750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM393_RS12775	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM393_RS12780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM393_RS12780	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM393_RS12785	COG0802	atpase or kinase
AM393_RS12790	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM393_RS12810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM393_RS12815	COG0330	HflC and HflK could
AM393_RS12820	COG0330	HflC and HflK could
AM393_RS12830	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AM393_RS12845	COG0557	exoribonuclease II activity
AM393_RS12850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM393_RS12855	COG1960	acyl-CoA dehydrogenase activity
AM393_RS12865	COG3650	response to hydrogen peroxide
AM393_RS12870	COG1073	alpha beta
AM393_RS12930	COG2965	DNA replication, synthesis of RNA primer
AM393_RS12935	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM393_RS12945	COG3061	Opacity-associated protein A
AM393_RS12950	COG0545	Peptidyl-prolyl cis-trans isomerase
AM393_RS12955	COG1113	amino acid transport
AM393_RS12965	COG0697	spore germination
AM393_RS12975	COG0702	epimerase
AM393_RS12980	COG1733	regulation of RNA biosynthetic process
AM393_RS12995	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM393_RS13010	COG1253	flavin adenine dinucleotide binding
AM393_RS13020	COG0729	surface antigen
AM393_RS13025	COG2911	Protein conserved in bacteria
AM393_RS13030	COG2105	PFAM AIG2 family protein
AM393_RS13050	COG1879	ABC-type sugar transport system periplasmic component
AM393_RS13055	COG1129	ABC transporter
AM393_RS13060	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS13065	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS13075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM393_RS13095	COG0312	modulator of DNA gyrase
AM393_RS13130	COG3964	amidohydrolase
AM393_RS13145	COG2706	6-phosphogluconolactonase activity
AM393_RS13150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS13150	COG3711	transcriptional antiterminator
AM393_RS13155	COG3077	Addiction module antitoxin, RelB DinJ family
AM393_RS13160	COG2026	Addiction module toxin, RelE StbE family
AM393_RS13165	COG0602	queuosine metabolic process
AM393_RS13185	COG1486	melibiose metabolic process
AM393_RS13190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS13195	COG0366	Alpha amylase catalytic
AM393_RS13200	COG1263	PTS System
AM393_RS13200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM393_RS13240	COG2731	YhcH YjgK YiaL family protein
AM393_RS13245	COG2222	sugar isomerase
AM393_RS13250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM393_RS13255	COG1228	amidohydrolase
AM393_RS13260	COG1288	antiporter activity
AM393_RS13265	COG2188	Transcriptional regulator
AM393_RS13290	COG0525	valine-tRNA ligase activity
AM393_RS13295	COG2927	DNA polymerase III (CHI subunit)
AM393_RS13310	COG0795	lipopolysaccharide-transporting ATPase activity
AM393_RS13315	COG0795	lipopolysaccharide-transporting ATPase activity
AM393_RS13320	COG0433	COG0433 Predicted ATPase
AM393_RS13335	COG3718	enzyme involved in inositol metabolism
AM393_RS13370	COG1737	Transcriptional regulator
AM393_RS13370	COG0837	glucose binding
AM393_RS13375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM393_RS13380	COG3962	Belongs to the TPP enzyme family
AM393_RS13390	COG1082	Xylose isomerase domain protein TIM barrel
AM393_RS13400	COG1653	transport
AM393_RS13405	COG3842	ATPase activity
AM393_RS13410	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM393_RS13415	COG0395	ABC-type sugar transport system, permease component
AM393_RS13420	COG1175	transmembrane transport
AM393_RS13425	COG1064	alcohol dehydrogenase
AM393_RS13430	COG0659	secondary active sulfate transmembrane transporter activity
AM393_RS13435	COG0288	reversible hydration of carbon dioxide
AM393_RS13450	COG0582	viral genome integration into host DNA
AM393_RS13515	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AM393_RS13515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM393_RS13560	COG3507	Belongs to the glycosyl hydrolase 43 family
AM393_RS13565	COG2211	Major facilitator Superfamily
AM393_RS13575	COG4580	involved in the transport of maltose and maltodextrins
AM393_RS13580	COG3272	Protein of unknown function (DUF1722)
AM393_RS13600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM393_RS13615	COG0300	oxidoreductase activity
AM393_RS13625	COG0789	Transcriptional regulator
AM393_RS13630	COG3040	lipid binding
AM393_RS13640	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM393_RS13645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM393_RS13650	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM393_RS13655	COG1538	Outer membrane efflux protein
AM393_RS13665	COG0745	RESPONSE REGULATOR receiver
AM393_RS13670	COG5002	protein histidine kinase activity
AM393_RS13685	COG2850	peptidyl-arginine hydroxylation
AM393_RS13715	COG0842	Transport permease protein
AM393_RS13720	COG1129	ABC transporter
AM393_RS13720	COG0842	Transport permease protein
AM393_RS13725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM393_RS13735	COG1879	ABC-type sugar transport system periplasmic component
AM393_RS13740	COG1129	ABC transporter
AM393_RS13745	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS13755	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM393_RS13760	COG0583	DNA-binding transcription factor activity
AM393_RS13770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM393_RS13775	COG5457	Domain of unknown function (DUF1127)
AM393_RS13785	COG1566	PFAM secretion protein HlyD family protein
AM393_RS13800	COG1924	4 iron, 4 sulfur cluster binding
AM393_RS13805	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AM393_RS13820	COG2733	membrane
AM393_RS13830	COG1917	Cupin 2, conserved barrel domain protein
AM393_RS13830	COG2207	Transcriptional regulator
AM393_RS13840	COG5464	transposase or invertase
AM393_RS13845	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS13855	COG0523	cobalamin synthesis protein
AM393_RS13860	COG2879	small protein
AM393_RS13865	COG1966	Carbon starvation protein
AM393_RS13880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM393_RS13885	COG2368	4-hydroxyphenylacetate
AM393_RS13905	COG3971	2-oxopent-4-enoate hydratase activity
AM393_RS13915	COG3384	dioxygenase
AM393_RS13920	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS13930	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM393_RS13940	COG1846	Transcriptional regulator
AM393_RS13970	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AM393_RS13985	COG3734	2-keto-3-deoxy-galactonokinase
AM393_RS13990	COG0800	Aldolase
AM393_RS13995	COG1737	Transcriptional regulator
AM393_RS14005	COG1214	PFAM Peptidase M22, glycoprotease
AM393_RS14005	COG0456	acetyltransferase
AM393_RS14010	COG2271	Major facilitator Superfamily
AM393_RS14015	COG1802	Transcriptional regulator
AM393_RS14020	COG1063	alcohol dehydrogenase
AM393_RS14030	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AM393_RS14030	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM393_RS14045	COG3715	PTS system
AM393_RS14050	COG3716	PTS system mannose fructose sorbose family IID component
AM393_RS14055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM393_RS14065	COG5464	transposase or invertase
AM393_RS14080	COG1484	DNA-dependent DNA replication
AM393_RS14095	COG2966	Psort location CytoplasmicMembrane, score
AM393_RS14115	COG2197	response regulator
AM393_RS14120	COG2197	response regulator
AM393_RS14125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM393_RS14130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS14130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS14135	COG4114	ferric iron reductase
AM393_RS14140	COG3706	GGDEF domain
AM393_RS14170	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AM393_RS14175	COG0456	acetyltransferase
AM393_RS14180	COG1011	Hydrolase
AM393_RS14190	COG2823	Periplasmic or secreted lipoprotein
AM393_RS14200	COG4667	esterase of the alpha-beta hydrolase superfamily
AM393_RS14205	COG0084	hydrolase, TatD family'
AM393_RS14210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM393_RS14240	COG3726	membrane protein affecting hemolysin expression
AM393_RS14250	COG0560	Phosphoserine phosphatase
AM393_RS14255	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AM393_RS14265	COG0488	(ABC) transporter
AM393_RS14275	COG0741	lytic transglycosylase activity
AM393_RS14295	COG3708	Transcriptional regulator
AM393_RS14295	COG2207	Transcriptional regulator
AM393_RS14300	COG3045	CreA protein
AM393_RS14305	COG0745	RESPONSE REGULATOR receiver
AM393_RS14310	COG2205	protein histidine kinase activity
AM393_RS14315	COG4452	Inner membrane protein CreD
AM393_RS14320	COG0745	RESPONSE REGULATOR receiver
AM393_RS14335	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM393_RS14345	COG0527	aspartate kinase activity
AM393_RS14345	COG0460	homoserine dehydrogenase
AM393_RS14355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM393_RS14370	COG1115	amino acid carrier protein
AM393_RS14375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM393_RS14380	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM393_RS14385	COG0477	Major facilitator Superfamily
AM393_RS14390	COG1584	GPR1 FUN34 yaaH family protein
AM393_RS14395	COG4735	regulation of single-species biofilm formation
AM393_RS14420	COG0583	DNA-binding transcription factor activity
AM393_RS14440	COG0196	riboflavin kinase activity
AM393_RS14455	COG1047	Peptidyl-prolyl cis-trans
AM393_RS14480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM393_RS14550	COG0505	Belongs to the CarA family
AM393_RS14605	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM393_RS14615	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM393_RS14620	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM393_RS14635	COG3493	citrate carrier protein
AM393_RS14650	COG0564	pseudouridine synthase activity
AM393_RS14660	COG0417	DNA replication proofreading
AM393_RS14665	COG0235	Class ii aldolase
AM393_RS14685	COG0586	Pfam SNARE associated Golgi protein
AM393_RS14695	COG1178	ABC-type Fe3 transport system permease component
AM393_RS14715	COG2814	Major facilitator Superfamily
AM393_RS14720	COG2271	Major facilitator Superfamily
AM393_RS14725	COG0583	DNA-binding transcription factor activity
AM393_RS14735	COG0738	Major facilitator superfamily
AM393_RS14785	COG0028	Belongs to the TPP enzyme family
AM393_RS14795	COG1609	Transcriptional regulator
AM393_RS14820	COG0768	penicillin binding
AM393_RS14825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM393_RS14830	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM393_RS14845	COG0772	Belongs to the SEDS family
AM393_RS14870	COG0849	cell division
AM393_RS14875	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM393_RS14895	COG0494	nUDIX hydrolase
AM393_RS14920	COG1459	type II secretion system
AM393_RS14925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM393_RS14930	COG4969	Belongs to the N-Me-Phe pilin family
AM393_RS14940	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM393_RS14945	COG3725	Membrane protein required for beta-lactamase induction
AM393_RS14950	COG3940	Belongs to the glycosyl hydrolase 43 family
AM393_RS14955	COG2211	Major facilitator Superfamily
AM393_RS14960	COG1113	amino acid transport
AM393_RS14965	COG2186	Transcriptional regulator
AM393_RS14970	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM393_RS14975	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM393_RS14980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM393_RS14995	COG3064	Membrane
AM393_RS15050	COG2132	Multicopper oxidase
AM393_RS15055	COG4993	Dehydrogenase
AM393_RS15065	COG0288	reversible hydration of carbon dioxide
AM393_RS15070	COG1131	(ABC) transporter
AM393_RS15075	COG0842	Transport permease protein
AM393_RS15080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS15085	COG0726	polysaccharide deacetylase
AM393_RS15105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM393_RS15110	COG0617	tRNA 3'-terminal CCA addition
AM393_RS15130	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM393_RS15135	COG1643	Atp-dependent helicase
AM393_RS15225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM393_RS15230	COG4774	siderophore transport
AM393_RS15235	COG1120	ATPase activity
AM393_RS15240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM393_RS15245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM393_RS15265	COG2860	membrane
AM393_RS15285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM393_RS15290	COG3835	regulator
AM393_RS15305	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AM393_RS15310	COG0024	Methionine aminopeptidase
AM393_RS15335	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM393_RS15350	COG0575	Belongs to the CDS family
AM393_RS15355	COG0750	zinc metalloprotease
AM393_RS15365	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AM393_RS15405	COG1982	Orn Lys Arg decarboxylase major
AM393_RS15410	COG0346	lactoylglutathione lyase activity
AM393_RS15420	COG4568	rho-dependent transcription termination
AM393_RS15435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM393_RS15440	COG3015	lipoprotein NlpE involved in copper resistance
AM393_RS15445	COG0791	NLP P60 protein
AM393_RS15455	COG1720	tRNA m6t6A37 methyltransferase activity
AM393_RS15465	COG1464	Belongs to the NlpA lipoprotein family
AM393_RS15470	COG2011	ABC-type metal ion transport system permease component
AM393_RS15480	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM393_RS15515	COG0656	L-ascorbic acid biosynthetic process
AM393_RS15520	COG0583	DNA-binding transcription factor activity
AM393_RS15525	COG2814	Major facilitator Superfamily
AM393_RS15535	COG2226	methyltransferase
AM393_RS15540	COG0741	lytic transglycosylase activity
AM393_RS15540	COG1388	LysM domain
AM393_RS15550	COG2226	methyltransferase
AM393_RS15560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM393_RS15570	COG0583	DNA-binding transcription factor activity
AM393_RS15580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM393_RS15585	COG1960	acyl-CoA dehydrogenase activity
AM393_RS15595	COG0121	glutamine amidotransferase
AM393_RS15600	COG3034	peptidoglycan biosynthetic process
AM393_RS15620	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM393_RS15625	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM393_RS15640	COG2991	Protein conserved in bacteria
AM393_RS15655	COG0454	-acetyltransferase
AM393_RS15660	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM393_RS15680	COG1802	Transcriptional regulator
AM393_RS15685	COG1113	amino acid transport
AM393_RS15690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM393_RS15695	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS15700	COG0579	oxidoreductase
AM393_RS15720	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AM393_RS15725	COG0625	glutathione transferase activity
AM393_RS15730	COG3775	system Galactitol-specific IIC component
AM393_RS15735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM393_RS15740	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS15745	COG1070	Carbohydrate kinase
AM393_RS15770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM393_RS15775	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM393_RS15780	COG0022	dehydrogenase e1 component
AM393_RS15785	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM393_RS15845	COG1192	Involved in chromosome partitioning
AM393_RS15850	COG0582	viral genome integration into host DNA
AM393_RS15875	COG0791	NLP P60 protein
AM393_RS15900	COG3639	organic phosphonate transmembrane transporter activity
AM393_RS15910	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM393_RS15935	COG3188	usher protein
AM393_RS15950	COG0765	amino acid transport
AM393_RS15955	COG0765	amino acid transport
AM393_RS15960	COG1126	abc transporter atp-binding protein
AM393_RS15965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM393_RS16000	COG4302	ethanolamine ammonia-lyase activity
AM393_RS16005	COG4303	Ethanolamine ammonia lyase large subunit
AM393_RS16015	COG0833	amino acid
AM393_RS16020	COG2040	homocysteine
AM393_RS16025	COG4521	taurine ABC transporter
AM393_RS16030	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AM393_RS16035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM393_RS16040	COG2175	clavaminate synthase activity
AM393_RS16050	COG0113	porphobilinogen synthase activity
AM393_RS16055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM393_RS16060	COG1335	isochorismatase
AM393_RS16065	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM393_RS16105	COG1785	Belongs to the alkaline phosphatase family
AM393_RS16115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM393_RS16125	COG3416	Protein conserved in bacteria
AM393_RS16130	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM393_RS16140	COG4126	flavin adenine dinucleotide binding
AM393_RS16155	COG1940	carbohydrate kinase activity
AM393_RS16160	COG0419	ATPase involved in DNA repair
AM393_RS16165	COG0420	3'-5' exonuclease activity
AM393_RS16190	COG0366	Alpha amylase catalytic
AM393_RS16195	COG0583	DNA-binding transcription factor activity
AM393_RS16200	COG1335	isochorismatase
AM393_RS16210	COG1228	amidohydrolase
AM393_RS16220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM393_RS16235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS16240	COG0450	alkyl hydroperoxide reductase
AM393_RS16260	COG1862	Preprotein translocase
AM393_RS16265	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM393_RS16270	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM393_RS16290	COG4238	major outer membrane lipoprotein
AM393_RS16300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM393_RS16300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM393_RS16320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM393_RS16325	COG0667	Aldo Keto reductase
AM393_RS16335	COG0142	geranyltranstransferase activity
AM393_RS16355	COG0693	protein deglycase activity
AM393_RS16360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM393_RS16370	COG2814	Major facilitator Superfamily
AM393_RS16375	COG0673	inositol 2-dehydrogenase activity
AM393_RS16390	COG1053	succinate dehydrogenase
AM393_RS16400	COG1053	succinate dehydrogenase
AM393_RS16405	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM393_RS16410	COG1414	Transcriptional regulator
AM393_RS16425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM393_RS16430	COG1845	cytochrome c oxidase, subunit III
AM393_RS16435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM393_RS16440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM393_RS16445	COG2223	nitrite transmembrane transporter activity
AM393_RS16450	COG3056	Lipoprotein
AM393_RS16455	COG0271	Belongs to the BolA IbaG family
AM393_RS16485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM393_RS16490	COG0776	regulation of translation
AM393_RS16495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM393_RS16500	COG1555	photosystem II stabilization
AM393_RS16505	COG0824	Thioesterase
AM393_RS16515	COG4533	DNA binding
AM393_RS16530	COG1522	sequence-specific DNA binding
AM393_RS16535	COG1132	(ABC) transporter
AM393_RS16540	COG1132	(ABC) transporter
AM393_RS16545	COG0347	Belongs to the P(II) protein family
AM393_RS16550	COG0004	ammonium transporteR
AM393_RS16555	COG1946	Acyl-CoA thioesterase
AM393_RS16560	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AM393_RS16565	COG3695	enzyme binding
AM393_RS16595	COG2364	Membrane
AM393_RS16610	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM393_RS16620	COG2182	Extracellular solute-binding protein
AM393_RS16625	COG1175	transmembrane transport
AM393_RS16630	COG3833	ABC-type maltose transport systems, permease component
AM393_RS16635	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AM393_RS16640	COG1874	Beta-galactosidase
AM393_RS16685	COG0110	maltose O-acetyltransferase activity
AM393_RS16700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM393_RS16705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM393_RS16710	COG1309	transcriptional regulator
AM393_RS16715	COG3264	Mechanosensitive ion channel
AM393_RS16715	COG1196	nuclear chromosome segregation
AM393_RS16720	COG5464	transposase or invertase
AM393_RS16730	COG3923	Primosomal replication protein n
AM393_RS16735	COG2832	Protein of unknown function (DUF454)
AM393_RS16775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM393_RS16780	COG4651	solute:proton antiporter activity
AM393_RS16780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM393_RS16785	COG2223	nitrite transmembrane transporter activity
AM393_RS16795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM393_RS16800	COG3735	TraB family
AM393_RS16815	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM393_RS16820	COG0330	HflC and HflK could
AM393_RS16825	COG4619	ABC transporter
AM393_RS16830	COG0390	transport system, permease component
AM393_RS16840	COG3118	belongs to the thioredoxin family
AM393_RS16845	COG0300	oxidoreductase activity
AM393_RS16850	COG2755	lipolytic protein G-D-S-L family
AM393_RS16855	COG4181	ATPase activity
AM393_RS16860	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM393_RS16875	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM393_RS16880	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM393_RS16900	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM393_RS16910	COG2501	S4 domain
AM393_RS16930	COG0582	viral genome integration into host DNA
AM393_RS17010	COG0305	Participates in initiation and elongation during chromosome replication
AM393_RS17080	COG3772	lysozyme
AM393_RS17265	COG3344	reverse transcriptase
AM393_RS17280	COG0582	viral genome integration into host DNA
AM393_RS17320	COG3539	Fimbrial protein
AM393_RS17325	COG3121	Chaperone
AM393_RS17330	COG3188	usher protein
AM393_RS17345	COG1560	Kdo2-lipid A biosynthetic process
AM393_RS17355	COG3710	Transcriptional regulator
AM393_RS17360	COG0531	amino acid
AM393_RS17365	COG1982	Orn Lys Arg decarboxylase major
AM393_RS17370	COG3104	oligopeptide transport
AM393_RS17405	COG0673	inositol 2-dehydrogenase activity
AM393_RS17420	COG1129	ABC transporter
AM393_RS17425	COG4211	Belongs to the binding-protein-dependent transport system permease family
AM393_RS17470	COG1566	PFAM secretion protein HlyD family protein
AM393_RS17475	COG1120	ATPase activity
AM393_RS17480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM393_RS17505	COG1473	amidohydrolase
AM393_RS17510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM393_RS17515	COG0667	Aldo Keto reductase
AM393_RS17565	COG0531	amino acid
AM393_RS17575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM393_RS17580	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS17595	COG1113	amino acid transport
AM393_RS17600	COG2211	Major facilitator Superfamily
AM393_RS17610	COG0673	inositol 2-dehydrogenase activity
AM393_RS17620	COG2771	luxR family
AM393_RS17635	COG3188	usher protein
AM393_RS17665	COG0668	transmembrane transport
AM393_RS17670	COG0477	Major facilitator Superfamily
AM393_RS17690	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM393_RS17690	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AM393_RS17695	COG2222	sugar isomerase
AM393_RS17700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM393_RS17705	COG3716	PTS system mannose fructose sorbose family IID component
AM393_RS17715	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM393_RS17725	COG0778	Nitroreductase
AM393_RS17730	COG2315	Protein conserved in bacteria
AM393_RS17780	COG3698	Phosphodiester glycosidase
AM393_RS17790	COG0697	spore germination
AM393_RS17805	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM393_RS17810	COG0765	amino acid transport
AM393_RS17815	COG4215	(ABC) transporter
AM393_RS17825	COG4221	oxidoreductase activity
AM393_RS17830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM393_RS17840	COG4608	Belongs to the ABC transporter superfamily
AM393_RS17845	COG0444	Belongs to the ABC transporter superfamily
AM393_RS17850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM393_RS17855	COG0601	transmembrane transport
AM393_RS17860	COG0747	negative chemotaxis
AM393_RS17890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM393_RS17900	COG0668	transmembrane transport
AM393_RS17905	COG0583	DNA-binding transcription factor activity
AM393_RS17915	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS17925	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS17930	COG1129	ABC transporter
AM393_RS17940	COG1879	ABC-type sugar transport system periplasmic component
AM393_RS17945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM393_RS17950	COG2390	Transcriptional regulator
AM393_RS17960	COG3959	Transketolase, thiamine diphosphate binding domain
AM393_RS17965	COG3958	Transketolase
AM393_RS17970	COG2977	Belongs to the P-Pant transferase superfamily
AM393_RS17975	COG4771	TonB-dependent receptor
AM393_RS17985	COG2382	esterase
AM393_RS17990	COG3251	PFAM MbtH domain protein
AM393_RS17995	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM393_RS17995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM393_RS18000	COG1120	ATPase activity
AM393_RS18005	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM393_RS18010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM393_RS18020	COG4592	Periplasmic binding protein
AM393_RS18025	COG1169	isochorismate synthase
AM393_RS18030	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM393_RS18035	COG1535	isochorismatase
AM393_RS18035	COG3433	isochorismatase activity
AM393_RS18040	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS18050	COG1966	Carbon starvation protein
AM393_RS18055	COG2879	small protein
AM393_RS18070	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS18075	COG0371	Dehydrogenase
AM393_RS18080	COG1129	ABC transporter
AM393_RS18085	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS18115	COG2271	Major facilitator Superfamily
AM393_RS18120	COG0483	inositol monophosphate 1-phosphatase activity
AM393_RS18130	COG0402	S-adenosylhomocysteine deaminase activity
AM393_RS18140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM393_RS18155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM393_RS18165	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS18170	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS18175	COG1129	ABC transporter
AM393_RS18200	COG0436	Aminotransferase
AM393_RS18205	COG1475	DNA binding
AM393_RS18210	COG3969	phosphoadenosine phosphosulfate
AM393_RS18215	COG0583	DNA-binding transcription factor activity
AM393_RS18220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM393_RS18240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM393_RS18245	COG3719	Belongs to the RNase T2 family
AM393_RS18250	COG3069	C4-dicarboxylate transmembrane transporter activity
AM393_RS18270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM393_RS18285	COG0583	DNA-binding transcription factor activity
AM393_RS18300	COG1686	Belongs to the peptidase S11 family
AM393_RS18305	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM393_RS18310	COG0772	Belongs to the SEDS family
AM393_RS18315	COG0768	penicillin binding
AM393_RS18325	COG0799	negative regulation of ribosome biogenesis
AM393_RS18345	COG1466	dna polymerase III delta subunit
AM393_RS18360	COG2888	peptidyl-tyrosine sulfation
AM393_RS18375	COG1126	abc transporter atp-binding protein
AM393_RS18380	COG0765	amino acid transport
AM393_RS18385	COG0765	amino acid transport
AM393_RS18400	COG4535	Mg2 and Co2 transporter CorC
AM393_RS18410	COG1702	phosphate starvation-inducible protein PhoH
AM393_RS18420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM393_RS18465	COG0367	asparagine synthase
AM393_RS18470	COG0647	UMP catabolic process
AM393_RS18475	COG1940	carbohydrate kinase activity
AM393_RS18475	COG1846	Transcriptional regulator
AM393_RS18480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM393_RS18525	COG0735	belongs to the Fur family
AM393_RS18540	COG0596	Alpha beta hydrolase
AM393_RS18550	COG0033	Phosphoglucomutase
AM393_RS18560	COG0745	RESPONSE REGULATOR receiver
AM393_RS18565	COG2205	protein histidine kinase activity
AM393_RS18595	COG0415	Belongs to the DNA photolyase family
AM393_RS18610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM393_RS18615	COG1984	allophanate hydrolase subunit 2
AM393_RS18655	COG2009	succinate dehydrogenase
AM393_RS18660	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM393_RS18665	COG1053	succinate dehydrogenase
AM393_RS18670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM393_RS18675	COG0567	Dehydrogenase, E1 component
AM393_RS18680	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM393_RS18690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM393_RS18700	COG1271	oxidase subunit
AM393_RS18705	COG1294	oxidase, subunit
AM393_RS18710	COG4890	Cyd operon protein YbgT
AM393_RS18715	COG3790	cyd operon protein YbgE
AM393_RS18720	COG0824	Thioesterase
AM393_RS18725	COG0811	peptide transport
AM393_RS18730	COG0848	biopolymer transport protein
AM393_RS18735	COG3064	Membrane
AM393_RS18745	COG2885	chlorophyll binding
AM393_RS18750	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM393_RS18795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM393_RS18800	COG3201	nicotinamide mononucleotide transporter
AM393_RS18815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM393_RS18825	COG2017	converts alpha-aldose to the beta-anomer
AM393_RS18835	COG1085	galactose-1-phosphate uridylyltransferase
AM393_RS18845	COG1119	ATPase activity
AM393_RS18855	COG2005	Transcriptional regulator
AM393_RS18855	COG3585	molybdate ion transport
AM393_RS18865	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM393_RS18870	COG4149	molybdate abc transporter
AM393_RS18875	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM393_RS18880	COG0561	phosphatase activity
AM393_RS18905	COG2200	EAL domain
AM393_RS18940	COG4677	pectinesterase activity
AM393_RS18980	COG1881	PFAM PEBP family protein
AM393_RS18985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM393_RS19000	COG2226	methyltransferase
AM393_RS19035	COG0642	Histidine kinase
AM393_RS19040	COG0745	RESPONSE REGULATOR receiver
AM393_RS19065	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM393_RS19075	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM393_RS19080	COG0314	molybdopterin synthase activity
AM393_RS19085	COG0670	Belongs to the BI1 family
AM393_RS19090	COG0392	lysyltransferase activity
AM393_RS19095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM393_RS19100	COG3568	Endonuclease Exonuclease Phosphatase
AM393_RS19110	COG0842	Transport permease protein
AM393_RS19115	COG0842	Transport permease protein
AM393_RS19120	COG1131	(ABC) transporter
AM393_RS19125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM393_RS19130	COG1309	transcriptional regulator
AM393_RS19135	COG0583	DNA-binding transcription factor activity
AM393_RS19140	COG2271	Major facilitator Superfamily
AM393_RS19145	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS19150	COG3959	Transketolase, thiamine diphosphate binding domain
AM393_RS19155	COG3958	Transketolase
AM393_RS19160	COG0513	Belongs to the DEAD box helicase family
AM393_RS19165	COG1199	ATP-dependent helicase activity
AM393_RS19170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM393_RS19180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM393_RS19190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM393_RS19200	COG0668	transmembrane transport
AM393_RS19205	COG1126	abc transporter atp-binding protein
AM393_RS19210	COG0765	amino acid transport
AM393_RS19215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM393_RS19230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM393_RS19235	COG2194	sulfuric ester hydrolase activity
AM393_RS19245	COG1321	iron dependent repressor
AM393_RS19250	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM393_RS19255	COG2723	6-phospho-beta-galactosidase activity
AM393_RS19260	COG2188	Transcriptional regulator
AM393_RS19265	COG1376	ErfK ybiS ycfS ynhG family protein
AM393_RS19270	COG2365	Tyrosine phosphatase family
AM393_RS19275	COG0488	(ABC) transporter
AM393_RS19290	COG2271	Major facilitator Superfamily
AM393_RS19295	COG1609	Transcriptional regulator
AM393_RS19305	COG0561	phosphatase activity
AM393_RS19310	COG1882	Formate acetyltransferase
AM393_RS19315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM393_RS19320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM393_RS19325	COG0303	'Molybdopterin
AM393_RS19340	COG0747	negative chemotaxis
AM393_RS19365	COG2223	nitrite transmembrane transporter activity
AM393_RS19375	COG2133	pyrroloquinoline quinone binding
AM393_RS19380	COG0625	glutathione transferase activity
AM393_RS19385	COG1686	Belongs to the peptidase S11 family
AM393_RS19390	COG1349	DNA-binding transcription factor activity
AM393_RS19395	COG0671	phosphoesterase, PA-phosphatase related
AM393_RS19405	COG2814	Major facilitator Superfamily
AM393_RS19410	COG0561	phosphatase activity
AM393_RS19415	COG0738	Major facilitator superfamily
AM393_RS19420	COG3226	Transcriptional regulator
AM393_RS19425	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM393_RS19435	COG3344	reverse transcriptase
AM393_RS19475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM393_RS19510	COG4695	Portal protein
AM393_RS19695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM393_RS19700	COG3842	ATPase activity
AM393_RS19705	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM393_RS19710	COG1177	transmembrane transport
AM393_RS19725	COG0745	RESPONSE REGULATOR receiver
AM393_RS19730	COG5002	protein histidine kinase activity
AM393_RS19735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM393_RS19740	COG4160	amino acid transport
AM393_RS19745	COG4215	(ABC) transporter
AM393_RS19750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM393_RS19755	COG1126	abc transporter atp-binding protein
AM393_RS19770	COG2203	Gaf domain
AM393_RS19770	COG5001	Diguanylate cyclase
AM393_RS19770	COG4251	negative regulation of phosphorylation
AM393_RS19770	COG3706	GGDEF domain
AM393_RS19775	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM393_RS19780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM393_RS19785	COG0702	epimerase
AM393_RS19790	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM393_RS19795	COG0028	Belongs to the TPP enzyme family
AM393_RS19810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM393_RS19820	COG2431	L-lysine efflux transmembrane transporter activity
AM393_RS19830	COG3593	DNA synthesis involved in DNA repair
AM393_RS19835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM393_RS19850	COG1278	Cold shock
AM393_RS19860	COG0542	response to heat
AM393_RS19875	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM393_RS19880	COG4988	ABC transporter
AM393_RS19885	COG0492	ferredoxin-NADP+ reductase activity
AM393_RS19900	COG1178	ABC-type Fe3 transport system permease component
AM393_RS19900	COG1674	ftsk spoiiie
AM393_RS19910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM393_RS19920	COG0243	molybdopterin cofactor binding
AM393_RS19925	COG0437	4 iron, 4 sulfur cluster binding
AM393_RS19930	COG3302	dmso reductase anchor subunit
AM393_RS19940	COG0477	Major facilitator Superfamily
AM393_RS19945	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM393_RS19950	COG1882	Formate acetyltransferase
AM393_RS19955	COG2116	formate transmembrane transporter activity
AM393_RS19960	COG1944	ATP diphosphatase activity
AM393_RS19965	COG2323	membrane
AM393_RS19985	COG0539	negative regulation of cytoplasmic translation
AM393_RS19995	COG0658	competence protein
AM393_RS19995	COG2333	competence protein COMEC
AM393_RS20010	COG3214	Protein conserved in bacteria
AM393_RS20025	COG3173	Aminoglycoside phosphotransferase
AM393_RS20030	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM393_RS20035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM393_RS20045	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AM393_RS20055	COG2989	Protein conserved in bacteria
AM393_RS20065	COG3108	Peptidase M15
AM393_RS20070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM393_RS20075	COG1448	Aminotransferase
AM393_RS20090	COG1522	sequence-specific DNA binding
AM393_RS20100	COG0814	amino acid
AM393_RS20110	COG1473	amidohydrolase
AM393_RS20120	COG0308	aminopeptidase N
AM393_RS20130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM393_RS20135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM393_RS20140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM393_RS20145	COG0431	NADPH-dependent FMN reductase
AM393_RS20160	COG0633	Ferredoxin
AM393_RS20160	COG3217	Mosc domain protein beta barrel domain protein
AM393_RS20170	COG0488	(ABC) transporter
AM393_RS20175	COG2995	paraquat-inducible protein a
AM393_RS20180	COG3008	intermembrane lipid transfer
AM393_RS20180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM393_RS20185	COG3009	Protein conserved in bacteria
AM393_RS20195	COG3130	regulation of translation
AM393_RS20205	COG1067	ATP-dependent peptidase activity
AM393_RS20230	COG3070	regulator of competence-specific genes
AM393_RS20235	COG1289	transmembrane transporter activity
AM393_RS20240	COG3304	Inner membrane component domain
AM393_RS20245	COG0210	DNA helicase
AM393_RS20255	COG1832	CoA-binding protein
AM393_RS20270	COG1881	PFAM PEBP family protein
AM393_RS20275	COG2207	Transcriptional regulator
AM393_RS20290	COG0670	Belongs to the BI1 family
AM393_RS20305	COG2200	EAL domain
AM393_RS20310	COG2200	EAL domain
AM393_RS20320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM393_RS20325	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS20330	COG4638	Rieske (2fe-2S)
AM393_RS20335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM393_RS20345	COG0473	3-isopropylmalate dehydrogenase activity
AM393_RS20350	COG0583	DNA-binding transcription factor activity
AM393_RS20355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM393_RS20360	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS20365	COG1396	sequence-specific DNA binding
AM393_RS20365	COG1917	Cupin 2, conserved barrel domain protein
AM393_RS20370	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM393_RS20375	COG0174	glutamine synthetase
AM393_RS20385	COG0531	amino acid
AM393_RS20400	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS20425	COG3729	General stress protein
AM393_RS20435	COG2233	PERMEase
AM393_RS20470	COG1309	transcriptional regulator
AM393_RS20485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM393_RS20495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM393_RS20515	COG1702	phosphate starvation-inducible protein PhoH
AM393_RS20520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM393_RS20535	COG1335	isochorismatase
AM393_RS20545	COG0583	DNA-binding transcription factor activity
AM393_RS20575	COG3381	protein complex oligomerization
AM393_RS20615	COG5645	(Lipo)protein
AM393_RS20635	COG1560	Kdo2-lipid A biosynthetic process
AM393_RS20685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM393_RS20705	COG2814	Major facilitator Superfamily
AM393_RS20710	COG0583	DNA-binding transcription factor activity
AM393_RS20715	COG1530	ribonuclease E activity
AM393_RS20730	COG1399	metal-binding, possibly nucleic acid-binding protein
AM393_RS20750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM393_RS20765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM393_RS20770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM393_RS20775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM393_RS20785	COG0470	DNA polymerase III
AM393_RS20790	COG0084	hydrolase, TatD family'
AM393_RS20800	COG0537	adenosine 5'-monophosphoramidase activity
AM393_RS20805	COG5633	Lipoprotein
AM393_RS20835	COG1252	NADH dehydrogenase
AM393_RS20840	COG3134	Outer membrane lipoprotein
AM393_RS20850	COG1309	transcriptional regulator
AM393_RS20860	COG1376	ErfK ybiS ycfS ynhG family protein
AM393_RS20860	COG1388	LysM domain
AM393_RS20865	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM393_RS20870	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM393_RS20880	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM393_RS20890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM393_RS20900	COG0318	PFAM AMP-dependent synthetase and ligase
AM393_RS20915	COG1177	transmembrane transport
AM393_RS20935	COG2850	peptidyl-arginine hydroxylation
AM393_RS20940	COG2205	protein histidine kinase activity
AM393_RS20960	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM393_RS20980	COG1187	pseudouridine synthase activity
AM393_RS20985	COG0538	isocitrate dehydrogenase activity
AM393_RS20990	COG0640	Transcriptional regulator
AM393_RS21005	COG3813	Protein conserved in bacteria
AM393_RS21010	COG1063	alcohol dehydrogenase
AM393_RS21015	COG3729	General stress protein
AM393_RS21020	COG3685	Protein conserved in bacteria
AM393_RS21025	COG3685	Protein conserved in bacteria
AM393_RS21030	COG3546	catalase activity
AM393_RS21035	COG1271	oxidase subunit
AM393_RS21040	COG1294	oxidase, subunit
AM393_RS21065	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM393_RS21070	COG0583	DNA-binding transcription factor activity
AM393_RS21075	COG3706	GGDEF domain
AM393_RS21080	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AM393_RS21095	COG1560	Kdo2-lipid A biosynthetic process
AM393_RS21105	COG3182	Iron-regulated membrane protein
AM393_RS21125	COG2199	diguanylate cyclase activity
AM393_RS21125	COG2203	Gaf domain
AM393_RS21130	COG3042	response to heat
AM393_RS21135	COG3189	MarR family transcriptional regulator
AM393_RS21140	COG1683	Conserved Protein
AM393_RS21145	COG0504	CTP synthase activity
AM393_RS21150	COG2807	transmembrane transport
AM393_RS21155	COG2207	Transcriptional regulator
AM393_RS21165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM393_RS21170	COG0859	PFAM glycosyl transferase family 9
AM393_RS21185	COG3344	reverse transcriptase
AM393_RS21190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM393_RS21195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM393_RS21200	COG0583	DNA-binding transcription factor activity
AM393_RS21205	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS21225	COG0386	Belongs to the glutathione peroxidase family
AM393_RS21240	COG2766	serine protein kinase
AM393_RS21245	COG3713	MltA-interacting MipA family protein
AM393_RS21250	COG0656	L-ascorbic acid biosynthetic process
AM393_RS21270	COG3139	Protein of unknown function (DUF1315)
AM393_RS21285	COG1063	alcohol dehydrogenase
AM393_RS21290	COG2271	Major facilitator Superfamily
AM393_RS21295	COG1063	alcohol dehydrogenase
AM393_RS21300	COG0191	fructose-bisphosphate aldolase activity
AM393_RS21305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM393_RS21310	COG0667	Aldo Keto reductase
AM393_RS21315	COG1349	DNA-binding transcription factor activity
AM393_RS21320	COG2814	Major facilitator Superfamily
AM393_RS21325	COG1335	isochorismatase
AM393_RS21330	COG0252	asparaginase activity
AM393_RS21335	COG0616	signal peptide processing
AM393_RS21340	COG0778	Nitroreductase
AM393_RS21360	COG0709	Synthesizes selenophosphate from selenide and ATP
AM393_RS21365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM393_RS21370	COG3321	synthase
AM393_RS21370	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS21370	COG0604	alcohol dehydrogenase
AM393_RS21375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM393_RS21380	COG0494	nUDIX hydrolase
AM393_RS21385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM393_RS21390	COG2897	thiosulfate sulfurtransferase activity
AM393_RS21395	COG4136	ATPase activity
AM393_RS21400	COG4135	transport system, permease component
AM393_RS21405	COG4134	Bacterial extracellular solute-binding protein
AM393_RS21410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM393_RS21415	COG0398	Pfam SNARE associated Golgi protein
AM393_RS21420	COG0398	Pfam SNARE associated Golgi protein
AM393_RS21425	COG0708	Exodeoxyribonuclease III
AM393_RS21435	COG3138	arginine N-succinyltransferase
AM393_RS21445	COG3724	N-succinylarginine dihydrolase activity
AM393_RS21455	COG3678	ATP-independent chaperone mediated protein folding
AM393_RS21460	COG0322	excinuclease ABC activity
AM393_RS21470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM393_RS21475	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS21480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS21485	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM393_RS21490	COG1917	Cupin 2, conserved barrel domain protein
AM393_RS21490	COG2169	Transcriptional regulator
AM393_RS21495	COG1486	melibiose metabolic process
AM393_RS21505	COG0753	catalase activity
AM393_RS21515	COG1823	symporter activity
AM393_RS21520	COG1988	membrane-bound metal-dependent
AM393_RS21525	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS21530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM393_RS21560	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM393_RS21565	COG3047	cAMP biosynthetic process
AM393_RS21575	COG4774	siderophore transport
AM393_RS21630	COG0134	indole-3-glycerol-phosphate synthase activity
AM393_RS21630	COG0135	phosphoribosylanthranilate isomerase activity
AM393_RS21635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM393_RS21635	COG0512	Glutamine amidotransferase of anthranilate synthase
AM393_RS21640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM393_RS21650	COG0009	L-threonylcarbamoyladenylate synthase
AM393_RS21660	COG0583	DNA-binding transcription factor activity
AM393_RS21670	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM393_RS21675	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS21685	COG0616	signal peptide processing
AM393_RS21720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM393_RS21730	COG0671	phosphoesterase, PA-phosphatase related
AM393_RS21735	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM393_RS21740	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM393_RS21750	COG0023	Translation Initiation Factor
AM393_RS21760	COG1349	DNA-binding transcription factor activity
AM393_RS21775	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM393_RS21775	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM393_RS21780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM393_RS21805	COG4171	peptide transport system, permease
AM393_RS21820	COG0702	epimerase
AM393_RS21835	COG1473	amidohydrolase
AM393_RS21845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM393_RS21850	COG1842	Phage shock protein A
AM393_RS21860	COG1983	PspC domain protein
AM393_RS21870	COG3106	COG3106 Predicted ATPase
AM393_RS21880	COG0583	DNA-binding transcription factor activity
AM393_RS21885	COG1486	melibiose metabolic process
AM393_RS21895	COG3180	Ammonia monooxygenase
AM393_RS21900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM393_RS21905	COG4948	Mandelate Racemase Muconate Lactonizing
AM393_RS21910	COG2866	Carboxypeptidase
AM393_RS21915	COG4166	transmembrane transport
AM393_RS21945	COG0656	L-ascorbic acid biosynthetic process
AM393_RS21965	COG0583	DNA-binding transcription factor activity
AM393_RS21970	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS21975	COG1078	dGTPase activity
AM393_RS21980	COG0693	protein deglycase activity
AM393_RS21985	COG0582	viral genome integration into host DNA
AM393_RS22085	COG0484	heat shock protein binding
AM393_RS22095	COG3772	lysozyme
AM393_RS22115	COG1783	phage Terminase large subunit
AM393_RS22125	COG2801	Transposase and inactivated derivatives
AM393_RS22130	COG3567	Phage-associated protein, HI1409 family
AM393_RS22200	COG0741	lytic transglycosylase activity
AM393_RS22200	COG0739	heme binding
AM393_RS22200	COG1196	nuclear chromosome segregation
AM393_RS22315	COG2885	chlorophyll binding
AM393_RS22415	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS22420	COG1309	transcriptional regulator
AM393_RS22425	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS22445	COG0583	DNA-binding transcription factor activity
AM393_RS22470	COG0604	alcohol dehydrogenase
AM393_RS22475	COG0436	Aminotransferase
AM393_RS22490	COG2011	ABC-type metal ion transport system permease component
AM393_RS22495	COG1448	Aminotransferase
AM393_RS22505	COG1522	sequence-specific DNA binding
AM393_RS22510	COG1113	amino acid transport
AM393_RS22525	COG0673	inositol 2-dehydrogenase activity
AM393_RS22530	COG1349	DNA-binding transcription factor activity
AM393_RS22550	COG0513	Belongs to the DEAD box helicase family
AM393_RS22560	COG0589	response to stress
AM393_RS22570	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM393_RS22575	COG0674	pyruvate-flavodoxin oxidoreductase activity
AM393_RS22575	COG1013	pyruvate-flavodoxin oxidoreductase activity
AM393_RS22575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AM393_RS22575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM393_RS22585	COG3042	response to heat
AM393_RS22590	COG3187	Heat shock protein
AM393_RS22595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM393_RS22600	COG0586	Pfam SNARE associated Golgi protein
AM393_RS22605	COG2911	Protein conserved in bacteria
AM393_RS22615	COG3784	Protein of unknown function (DUF1318)
AM393_RS22620	COG2207	Transcriptional regulator
AM393_RS22625	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS22650	COG2030	dehydratase
AM393_RS22650	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS22655	COG3396	Phenylacetate-CoA oxygenase
AM393_RS22660	COG3460	Phenylacetate-CoA oxygenase
AM393_RS22665	COG3396	Phenylacetate-CoA oxygenase
AM393_RS22670	COG2151	metal-sulfur cluster biosynthetic enzyme
AM393_RS22675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM393_RS22680	COG1024	Enoyl-CoA hydratase
AM393_RS22685	COG1024	Enoyl-CoA hydratase
AM393_RS22690	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM393_RS22695	COG2050	protein possibly involved in aromatic compounds catabolism
AM393_RS22700	COG0183	Belongs to the thiolase family
AM393_RS22705	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM393_RS22710	COG3327	negative regulation of DNA-templated transcription, initiation
AM393_RS22715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM393_RS22730	COG1643	Atp-dependent helicase
AM393_RS22735	COG4122	O-methyltransferase activity
AM393_RS22760	COG0583	DNA-binding transcription factor activity
AM393_RS22765	COG0667	Aldo Keto reductase
AM393_RS22770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM393_RS22775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM393_RS22780	COG3138	arginine N-succinyltransferase
AM393_RS22785	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS22790	COG3724	N-succinylarginine dihydrolase activity
AM393_RS22795	COG2988	succinylglutamate desuccinylase activity
AM393_RS22800	COG1113	amino acid transport
AM393_RS22805	COG0477	Major facilitator Superfamily
AM393_RS22810	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM393_RS22815	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS22820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM393_RS22825	COG0401	homolog of Blt101
AM393_RS22830	COG5562	phage envelope protein
AM393_RS22835	COG0425	Belongs to the sulfur carrier protein TusA family
AM393_RS22840	COG2391	methyltransferase activity
AM393_RS22865	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AM393_RS22870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM393_RS22870	COG1263	PTS System
AM393_RS22875	COG1609	Transcriptional regulator
AM393_RS22880	COG5339	Protein conserved in bacteria
AM393_RS22885	COG1482	cell wall glycoprotein biosynthetic process
AM393_RS22890	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM393_RS22890	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM393_RS22895	COG0114	fumarate hydratase activity
AM393_RS22905	COG2205	protein histidine kinase activity
AM393_RS22915	COG0745	RESPONSE REGULATOR receiver
AM393_RS22920	COG3136	membrane protein required for alginate biosynthesis
AM393_RS22930	COG0531	amino acid
AM393_RS22950	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM393_RS22955	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM393_RS22970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM393_RS22985	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM393_RS22990	COG1473	amidohydrolase
AM393_RS23000	COG0583	DNA-binding transcription factor activity
AM393_RS23005	COG2840	Smr protein MutS2
AM393_RS23010	COG1414	Transcriptional regulator
AM393_RS23020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM393_RS23025	COG0183	Belongs to the thiolase family
AM393_RS23035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM393_RS23040	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM393_RS23060	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM393_RS23060	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM393_RS23085	COG4565	transcriptional regulatory protein
AM393_RS23090	COG3290	protein histidine kinase activity
AM393_RS23115	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM393_RS23125	COG0679	Auxin Efflux Carrier
AM393_RS23155	COG0628	permease
AM393_RS23180	COG3591	Belongs to the peptidase S1B family
AM393_RS23195	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AM393_RS23200	COG2814	Major facilitator Superfamily
AM393_RS23205	COG0583	DNA-binding transcription factor activity
AM393_RS23210	COG1940	carbohydrate kinase activity
AM393_RS23215	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM393_RS23230	COG3302	dmso reductase anchor subunit
AM393_RS23235	COG0437	4 iron, 4 sulfur cluster binding
AM393_RS23255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM393_RS23270	COG2271	Major facilitator Superfamily
AM393_RS23275	COG0246	Mannitol dehydrogenase
AM393_RS23280	COG0589	response to stress
AM393_RS23285	COG1802	Transcriptional regulator
AM393_RS23290	COG4221	oxidoreductase activity
AM393_RS23305	COG2207	Transcriptional regulator
AM393_RS23310	COG2135	peptidase activity
AM393_RS23315	COG2197	response regulator
AM393_RS23330	COG0071	Belongs to the small heat shock protein (HSP20) family
AM393_RS23335	COG1546	Belongs to the CinA family
AM393_RS23340	COG2200	EAL domain
AM393_RS23355	COG3708	Transcriptional regulator
AM393_RS23355	COG2207	Transcriptional regulator
AM393_RS23360	COG2610	gluconate transmembrane transporter activity
AM393_RS23365	COG3622	Belongs to the hyi family
AM393_RS23370	COG0235	Class ii aldolase
AM393_RS23375	COG3395	kinase activity
AM393_RS23380	COG2084	Dehydrogenase
AM393_RS23385	COG1349	DNA-binding transcription factor activity
AM393_RS23400	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM393_RS23405	COG2223	nitrite transmembrane transporter activity
AM393_RS23440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM393_RS23445	COG0683	leucine binding
AM393_RS23465	COG0410	ABC transporter
AM393_RS23475	COG2814	Major facilitator Superfamily
AM393_RS23480	COG0697	spore germination
AM393_RS23490	COG4977	sequence-specific DNA binding
AM393_RS23515	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS23520	COG2731	YhcH YjgK YiaL family protein
AM393_RS23535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM393_RS23545	COG3395	kinase activity
AM393_RS23550	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM393_RS23555	COG1349	DNA-binding transcription factor activity
AM393_RS23560	COG0039	L-malate dehydrogenase activity
AM393_RS23570	COG0583	DNA-binding transcription factor activity
AM393_RS23575	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS23590	COG2199	diguanylate cyclase activity
AM393_RS23675	COG0477	Major facilitator Superfamily
AM393_RS23685	COG2070	2-Nitropropane dioxygenase
AM393_RS23690	COG2011	ABC-type metal ion transport system permease component
AM393_RS23710	COG4628	conserved protein (DUF2132)
AM393_RS23725	COG2207	Transcriptional regulator
AM393_RS23755	COG2233	PERMEase
AM393_RS23760	COG3648	Uricase
AM393_RS23760	COG3195	allantoin biosynthetic process
AM393_RS23765	COG2351	hydroxyisourate hydrolase activity
AM393_RS23770	COG1396	sequence-specific DNA binding
AM393_RS23775	COG3550	peptidyl-serine autophosphorylation
AM393_RS23780	COG1649	PFAM Uncharacterised BCR, COG1649
AM393_RS23790	COG3188	usher protein
AM393_RS23825	COG5001	Diguanylate cyclase
AM393_RS23825	COG3300	MHYT domain
AM393_RS23830	COG2819	hydrolase of the alpha beta superfamily
AM393_RS23840	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS23840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS23845	COG2814	Major facilitator Superfamily
AM393_RS23860	COG1263	PTS System
AM393_RS23860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM393_RS23865	COG2186	Transcriptional regulator
AM393_RS23885	COG3835	regulator
AM393_RS23890	COG1929	Belongs to the glycerate kinase type-1 family
AM393_RS23935	COG0738	Major facilitator superfamily
AM393_RS23940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM393_RS23945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM393_RS23950	COG1349	DNA-binding transcription factor activity
AM393_RS23965	COG1349	DNA-binding transcription factor activity
AM393_RS23970	COG4977	sequence-specific DNA binding
AM393_RS23990	COG4977	sequence-specific DNA binding
AM393_RS24000	COG2801	Transposase and inactivated derivatives
AM393_RS24010	COG0667	Aldo Keto reductase
AM393_RS24020	COG0667	Aldo Keto reductase
AM393_RS24025	COG0667	Aldo Keto reductase
AM393_RS24035	COG0456	acetyltransferase
AM393_RS24035	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM393_RS24065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM393_RS24065	COG0426	domain, Protein
AM393_RS24080	COG1652	LysM domain
AM393_RS24110	COG1609	Transcriptional regulator
AM393_RS24120	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM393_RS24135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM393_RS24145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM393_RS24150	COG0583	DNA-binding transcription factor activity
AM393_RS24155	COG0583	DNA-binding transcription factor activity
AM393_RS24170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM393_RS24170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM393_RS24170	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM393_RS24175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM393_RS24185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM393_RS24195	COG3037	sugar-specific permease SgaT UlaA
AM393_RS24205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM393_RS24210	COG1609	Transcriptional regulator
AM393_RS24220	COG2223	nitrite transmembrane transporter activity
AM393_RS24250	COG0477	Major facilitator Superfamily
AM393_RS24255	COG4529	Protein conserved in bacteria
AM393_RS24260	COG1902	pentaerythritol trinitrate reductase activity
AM393_RS24270	COG0583	DNA-binding transcription factor activity
AM393_RS24275	COG2070	2-Nitropropane dioxygenase
AM393_RS24285	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM393_RS24295	COG0765	amino acid transport
AM393_RS24360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM393_RS24395	COG1335	isochorismatase
AM393_RS24400	COG0406	alpha-ribazole phosphatase activity
AM393_RS24435	COG1953	Uracil, thiamine, allantoin
AM393_RS24440	COG0402	S-adenosylhomocysteine deaminase activity
AM393_RS24445	COG3706	GGDEF domain
AM393_RS24450	COG1609	Transcriptional regulator
AM393_RS24460	COG0673	inositol 2-dehydrogenase activity
AM393_RS24470	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM393_RS24475	COG1116	anion transmembrane transporter activity
AM393_RS24480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM393_RS24485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM393_RS24490	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM393_RS24495	COG0076	glutamate decarboxylase activity
AM393_RS24510	COG2205	protein histidine kinase activity
AM393_RS24520	COG0596	Alpha beta hydrolase
AM393_RS24560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM393_RS24560	COG0519	Catalyzes the synthesis of GMP from XMP
AM393_RS24580	COG0583	DNA-binding transcription factor activity
AM393_RS24590	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM393_RS24595	COG1285	pathogenesis
AM393_RS24605	COG2814	Major facilitator Superfamily
AM393_RS24610	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM393_RS24615	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS24640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM393_RS24645	COG0583	DNA-binding transcription factor activity
AM393_RS24650	COG0243	molybdopterin cofactor binding
AM393_RS24655	COG3781	membrane
AM393_RS24680	COG1764	response to oxidative stress
AM393_RS24690	COG3111	PFAM Bacterial OB fold (BOF) protein
AM393_RS24700	COG2323	membrane
AM393_RS24720	COG3685	Protein conserved in bacteria
AM393_RS24735	COG3729	General stress protein
AM393_RS24740	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS24780	COG0488	(ABC) transporter
AM393_RS24795	COG1064	alcohol dehydrogenase
AM393_RS24800	COG0747	negative chemotaxis
AM393_RS24810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM393_RS24820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM393_RS24830	COG2814	Major facilitator Superfamily
AM393_RS24840	COG2326	polyphosphate kinase activity
AM393_RS24855	COG2864	formate dehydrogenase
AM393_RS24860	COG0437	4 iron, 4 sulfur cluster binding
AM393_RS24885	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM393_RS24895	COG3485	protocatechuate 3,4-dioxygenase
AM393_RS24900	COG4829	muconolactone delta-isomerase
AM393_RS24905	COG4948	Mandelate Racemase Muconate Lactonizing
AM393_RS24910	COG1414	Transcriptional regulator
AM393_RS24930	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM393_RS24935	COG1140	nitrate reductase beta subunit
AM393_RS24940	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM393_RS24945	COG2181	nitrate reductase activity
AM393_RS24950	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AM393_RS24955	COG1178	ABC-type Fe3 transport system permease component
AM393_RS24960	COG1840	ABC-type Fe3 transport system, periplasmic component
AM393_RS24965	COG3842	ATPase activity
AM393_RS24970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM393_RS24985	COG2211	Major facilitator Superfamily
AM393_RS25015	COG0625	glutathione transferase activity
AM393_RS25025	COG1126	abc transporter atp-binding protein
AM393_RS25030	COG0765	amino acid transport
AM393_RS25040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM393_RS25045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM393_RS25050	COG1473	amidohydrolase
AM393_RS25055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM393_RS25060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM393_RS25085	COG4772	TonB-dependent receptor
AM393_RS25090	COG1228	amidohydrolase
AM393_RS25095	COG3691	Protein conserved in bacteria
AM393_RS25110	COG2130	NADP-dependent
AM393_RS25120	COG1247	-acetyltransferase
AM393_RS25125	COG3238	Protein conserved in bacteria
AM393_RS25135	COG0747	negative chemotaxis
AM393_RS25140	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS25175	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS25180	COG1177	transmembrane transport
AM393_RS25185	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM393_RS25190	COG3842	ATPase activity
AM393_RS25195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM393_RS25200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM393_RS25205	COG1271	oxidase subunit
AM393_RS25210	COG1294	oxidase, subunit
AM393_RS25230	COG0826	peptidase U32
AM393_RS25240	COG1396	sequence-specific DNA binding
AM393_RS25245	COG3135	benzoate transporter
AM393_RS25250	COG2207	Transcriptional regulator
AM393_RS25250	COG3708	Transcriptional regulator
AM393_RS25265	COG0500	methyltransferase
AM393_RS25270	COG1275	C4-dicarboxylate transporter malic acid transport protein
AM393_RS25275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM393_RS25280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM393_RS25295	COG2272	Belongs to the type-B carboxylesterase lipase family
AM393_RS25300	COG5383	Protein conserved in bacteria
AM393_RS25305	COG3485	protocatechuate 3,4-dioxygenase
AM393_RS25310	COG3485	protocatechuate 3,4-dioxygenase
AM393_RS25315	COG0583	DNA-binding transcription factor activity
AM393_RS25335	COG3038	cytochrome b561
AM393_RS25355	COG2814	Major facilitator Superfamily
AM393_RS25365	COG0673	inositol 2-dehydrogenase activity
AM393_RS25375	COG2723	6-phospho-beta-galactosidase activity
AM393_RS25410	COG4659	FMN binding
AM393_RS25420	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM393_RS25435	COG0625	glutathione transferase activity
AM393_RS25440	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM393_RS25455	COG3895	Periplasmic Protein
AM393_RS25470	COG3706	GGDEF domain
AM393_RS25485	COG1566	PFAM secretion protein HlyD family protein
AM393_RS25490	COG1289	transmembrane transporter activity
AM393_RS25495	COG2032	superoxide dismutase activity
AM393_RS25500	COG4989	oxidoreductase activity
AM393_RS25505	COG3313	Fe-S protein
AM393_RS25510	COG1309	transcriptional regulator
AM393_RS25515	COG1902	pentaerythritol trinitrate reductase activity
AM393_RS25520	COG0346	lactoylglutathione lyase activity
AM393_RS25530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM393_RS25535	COG0791	NLP P60 protein
AM393_RS25550	COG2814	Major facilitator Superfamily
AM393_RS25560	COG0583	DNA-binding transcription factor activity
AM393_RS25565	COG2814	Major facilitator Superfamily
AM393_RS25570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM393_RS25575	COG0307	riboflavin synthase, alpha
AM393_RS25630	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AM393_RS25660	COG1349	DNA-binding transcription factor activity
AM393_RS25665	COG0346	lactoylglutathione lyase activity
AM393_RS25690	COG0444	Belongs to the ABC transporter superfamily
AM393_RS25695	COG4608	Belongs to the ABC transporter superfamily
AM393_RS25725	COG3321	synthase
AM393_RS25725	COG0604	alcohol dehydrogenase
AM393_RS25725	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS25770	COG0402	S-adenosylhomocysteine deaminase activity
AM393_RS25795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM393_RS25800	COG0277	FAD linked oxidase domain protein
AM393_RS25825	COG0583	DNA-binding transcription factor activity
AM393_RS25835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM393_RS25845	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM393_RS25850	COG2610	gluconate transmembrane transporter activity
AM393_RS25855	COG1028	Short-chain dehydrogenase reductase Sdr
AM393_RS25890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM393_RS25910	COG0745	RESPONSE REGULATOR receiver
AM393_RS25915	COG5002	protein histidine kinase activity
AM393_RS25915	COG3850	Histidine kinase
AM393_RS25930	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AM393_RS25965	COG4235	cytochrome complex assembly
AM393_RS25965	COG3088	subunit of a heme lyase
AM393_RS25970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM393_RS25975	COG1138	Cytochrome C-type biogenesis protein
AM393_RS25990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM393_RS25995	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM393_RS26000	COG4133	protoheme IX ABC transporter activity
AM393_RS26030	COG1175	transmembrane transport
AM393_RS26045	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM393_RS26050	COG3383	formate dehydrogenase (NAD+) activity
AM393_RS26055	COG1473	amidohydrolase
AM393_RS26085	COG1126	abc transporter atp-binding protein
AM393_RS26090	COG0765	amino acid transport
AM393_RS26110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM393_RS26115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM393_RS26120	COG1120	ATPase activity
AM393_RS26125	COG4774	siderophore transport
AM393_RS26130	COG1116	anion transmembrane transporter activity
AM393_RS26135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM393_RS26155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM393_RS26160	COG0583	DNA-binding transcription factor activity
AM393_RS26180	COG2814	Major facilitator Superfamily
AM393_RS26215	COG1414	Transcriptional regulator
AM393_RS26220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM393_RS26225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM393_RS26230	COG1120	ATPase activity
AM393_RS26240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM393_RS26245	COG2271	Major facilitator Superfamily
AM393_RS26250	COG1082	Xylose isomerase domain protein TIM barrel
AM393_RS26250	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AM393_RS26255	COG1309	transcriptional regulator
AM393_RS26280	COG1376	ErfK ybiS ycfS ynhG family protein
AM393_RS26295	COG0719	Fe-S assembly protein
AM393_RS26300	COG0396	ATPase activity
AM393_RS26305	COG0719	Fe-S assembly protein
AM393_RS26310	COG0316	Belongs to the HesB IscA family
AM393_RS26325	COG1309	transcriptional regulator
AM393_RS26330	COG1304	FMN binding
AM393_RS26355	COG0583	DNA-binding transcription factor activity
AM393_RS26365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM393_RS26370	COG1120	ATPase activity
AM393_RS26400	COG2261	transglycosylase associated protein
AM393_RS26405	COG2050	protein possibly involved in aromatic compounds catabolism
AM393_RS26410	COG0277	FAD linked oxidase domain protein
AM393_RS26410	COG0247	lactate metabolic process
AM393_RS26415	COG0628	permease
AM393_RS26425	COG0574	Belongs to the PEP-utilizing enzyme family
AM393_RS26425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM393_RS26440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM393_RS26445	COG4256	Hemin uptake protein
AM393_RS26455	COG0791	NLP P60 protein
AM393_RS26465	COG0386	Belongs to the glutathione peroxidase family
AM393_RS26485	COG0583	DNA-binding transcription factor activity
AM393_RS26505	COG0072	phenylalanine-tRNA ligase activity
AM393_RS26505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM393_RS26545	COG3137	Salt-induced outer membrane protein
AM393_RS26550	COG1105	Belongs to the carbohydrate kinase PfkB family
AM393_RS26560	COG3001	Fructosamine kinase
AM393_RS26570	COG2350	Protein conserved in bacteria
AM393_RS26575	COG2353	YceI-like domain
AM393_RS26595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM393_RS26605	COG0444	Belongs to the ABC transporter superfamily
AM393_RS26610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM393_RS26615	COG0601	transmembrane transport
AM393_RS26620	COG4166	transmembrane transport
AM393_RS26625	COG2095	MarC family integral membrane protein
AM393_RS26635	COG1454	alcohol dehydrogenase
AM393_RS26635	COG1012	belongs to the aldehyde dehydrogenase family
AM393_RS26640	COG1435	thymidine kinase activity
AM393_RS26645	COG2916	Histone family protein nucleoid-structuring protein H-NS
AM393_RS26650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM393_RS26655	COG0745	RESPONSE REGULATOR receiver
AM393_RS26660	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM393_RS26670	COG0788	formyltetrahydrofolate deformylase activity
AM393_RS26705	COG1522	sequence-specific DNA binding
AM393_RS26715	COG2181	nitrate reductase activity
AM393_RS26720	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM393_RS26725	COG1140	nitrate reductase beta subunit
AM393_RS26730	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM393_RS26735	COG2223	nitrite transmembrane transporter activity
AM393_RS26740	COG3850	Histidine kinase
AM393_RS26745	COG2197	response regulator
AM393_RS26750	COG4932	domain protein
AM393_RS26755	COG0243	molybdopterin cofactor binding
AM393_RS26760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM393_RS26760	COG2146	nitrite reductase [NAD(P)H] activity
AM393_RS26765	COG1116	anion transmembrane transporter activity
AM393_RS26775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM393_RS26780	COG3707	response regulator
AM393_RS26785	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM393_RS26795	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM393_RS26800	COG4572	Cation transport regulator
AM393_RS26805	COG0387	Pfam Sodium calcium exchanger
AM393_RS26825	COG2890	protein-(glutamine-N5) methyltransferase activity
AM393_RS26860	COG0659	secondary active sulfate transmembrane transporter activity
AM393_RS26880	COG0012	GTP binding
AM393_RS27095	COG5499	transcription regulator containing HTH domain
AM393_RS27185	COG1475	DNA binding
AM393_RS27265	COG3344	reverse transcriptase
AM393_RS27330	COG2199	diguanylate cyclase activity
AM393_RS27330	COG2203	Gaf domain
AM393_RS27335	COG5001	Diguanylate cyclase
AM393_RS27335	COG1716	ATPase activity
AM393_RS27350	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM393_RS27360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM393_RS27410	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM393_RS27440	COG0739	heme binding
AM393_RS27450	COG2132	Multicopper oxidase
AM393_RS27455	COG3667	copper resistance
AM393_RS27460	COG2372	response to copper ion
AM393_RS27465	COG1276	copper resistance
AM393_RS27470	COG0745	RESPONSE REGULATOR receiver
AM393_RS27475	COG2205	protein histidine kinase activity
AM393_RS27495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AM393_RS27510	COG0431	NADPH-dependent FMN reductase
AM393_RS27540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM393_RS27590	COG3436	PFAM IS66 Orf2 family protein
AM393_RS27595	COG4372	Transposase
AM393_RS27640	COG2801	Transposase and inactivated derivatives
AM393_RS27790	COG0697	spore germination
AM393_RS27820	COG3173	Aminoglycoside phosphotransferase
AM393_RS27850	COG4372	Transposase
AM393_RS27855	COG3436	PFAM IS66 Orf2 family protein
AM393_RS27870	COG2801	Transposase and inactivated derivatives
AM393_RS27915	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AM393_RS27920	COG3012	SEC-C Motif Domain Protein
AM393_RS27920	COG3318	Belongs to the UPF0149 family
AM393_RS27940	COG3039	Transposase
AM393_RS27950	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AM393_RS28045	COG4644	lycopene metabolic process
AM393_RS28050	COG0673	inositol 2-dehydrogenase activity
AM393_RS28070	COG2826	transposase and inactivated derivatives, IS30 family
AM393_RS28140	COG0741	lytic transglycosylase activity
AM393_RS28255	COG4372	Transposase
AM393_RS28270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM393_RS28325	COG2003	Belongs to the UPF0758 family
AM393_RS28420	COG1192	Involved in chromosome partitioning
AM393_RS28535	COG2135	peptidase activity
AM393_RS28545	COG3039	Transposase
AM393_RS28640	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM393_RS28680	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM393_RS28685	COG1842	Phage shock protein A
AM393_RS28695	COG1983	PspC domain protein
AM393_RS28705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM393_RS28710	COG3106	COG3106 Predicted ATPase
AM393_RS28980	COG3344	reverse transcriptase
AM393_RS29005	COG0789	Transcriptional regulator
AM393_RS29135	COG1196	nuclear chromosome segregation
AM393_RS29145	COG4372	Transposase
AM393_RS29150	COG3436	PFAM IS66 Orf2 family protein