locus-tag	class	description
HBJ12_RS00020	COG0187	DNA topoisomerase II activity
HBJ12_RS00025	COG0561	phosphatase activity
HBJ12_RS00040	COG2186	Transcriptional regulator
HBJ12_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
HBJ12_RS00050	COG0800	Aldolase
HBJ12_RS00060	COG2271	Major facilitator Superfamily
HBJ12_RS00070	COG5645	(Lipo)protein
HBJ12_RS00085	COG3645	SOS response
HBJ12_RS00095	COG2188	Transcriptional regulator
HBJ12_RS00110	COG2149	membrane
HBJ12_RS00130	COG2610	gluconate transmembrane transporter activity
HBJ12_RS00140	COG0583	DNA-binding transcription factor activity
HBJ12_RS00145	COG2814	Major facilitator Superfamily
HBJ12_RS00175	COG0028	Belongs to the TPP enzyme family
HBJ12_RS00180	COG0440	acetolactate synthase activity
HBJ12_RS00185	COG2197	response regulator
HBJ12_RS00195	COG2271	Major facilitator Superfamily
HBJ12_RS00235	COG2188	Transcriptional regulator
HBJ12_RS00260	COG4580	involved in the transport of maltose and maltodextrins
HBJ12_RS00265	COG1447	Phosphotransferase system cellobiose-specific component IIA
HBJ12_RS00270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS00270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS00280	COG1609	Transcriptional regulator
HBJ12_RS00290	COG3384	dioxygenase
HBJ12_RS00295	COG0583	DNA-binding transcription factor activity
HBJ12_RS00300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HBJ12_RS00305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HBJ12_RS00310	COG2828	Protein conserved in bacteria
HBJ12_RS00325	COG0697	spore germination
HBJ12_RS00330	COG1263	PTS System
HBJ12_RS00330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBJ12_RS00340	COG2814	Major facilitator Superfamily
HBJ12_RS00350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBJ12_RS00385	COG0583	DNA-binding transcription factor activity
HBJ12_RS00410	COG1464	Belongs to the NlpA lipoprotein family
HBJ12_RS00425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HBJ12_RS00435	COG1064	alcohol dehydrogenase
HBJ12_RS00465	COG2211	Major facilitator Superfamily
HBJ12_RS00470	COG1501	Belongs to the glycosyl hydrolase 31 family
HBJ12_RS00480	COG1486	melibiose metabolic process
HBJ12_RS00485	COG1263	PTS System
HBJ12_RS00485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBJ12_RS00490	COG2982	Protein involved in outer membrane biogenesis
HBJ12_RS00495	COG2233	PERMEase
HBJ12_RS00500	COG0786	glutamate:sodium symporter activity
HBJ12_RS00520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HBJ12_RS00545	COG3152	Membrane
HBJ12_RS00555	COG1494	fructose-1,6-bisphosphatase
HBJ12_RS00560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBJ12_RS00565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBJ12_RS00570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBJ12_RS00590	COG2860	membrane
HBJ12_RS00600	COG2169	Transcriptional regulator
HBJ12_RS00600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBJ12_RS00605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HBJ12_RS00610	COG1561	YicC-like family, N-terminal region
HBJ12_RS00630	COG1131	(ABC) transporter
HBJ12_RS00635	COG0842	Transport permease protein
HBJ12_RS00660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBJ12_RS00695	COG1519	Transferase
HBJ12_RS00700	COG1216	Glycosyl transferase, family 2
HBJ12_RS00705	COG0438	transferase activity, transferring glycosyl groups
HBJ12_RS00715	COG0859	PFAM glycosyl transferase family 9
HBJ12_RS00740	COG0859	PFAM glycosyl transferase family 9
HBJ12_RS00755	COG0156	8-amino-7-oxononanoate synthase activity
HBJ12_RS00765	COG0463	Glycosyl transferase, family 2
HBJ12_RS00770	COG2861	carbohydrate metabolic process
HBJ12_RS00775	COG4942	peptidase
HBJ12_RS00785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBJ12_RS00790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HBJ12_RS00810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HBJ12_RS00820	COG2186	Transcriptional regulator
HBJ12_RS00840	COG3722	fumarate hydratase activity
HBJ12_RS00860	COG1566	PFAM secretion protein HlyD family protein
HBJ12_RS00865	COG0625	glutathione transferase activity
HBJ12_RS00875	COG3276	selenocysteine insertion sequence binding
HBJ12_RS00880	COG1414	Transcriptional regulator
HBJ12_RS00885	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBJ12_RS00890	COG3977	Valine--pyruvate aminotransferase
HBJ12_RS00895	COG0366	Alpha amylase catalytic
HBJ12_RS00900	COG2992	FlgJ-related protein
HBJ12_RS00905	COG1609	Transcriptional regulator
HBJ12_RS00905	COG2207	Transcriptional regulator
HBJ12_RS00910	COG4214	carbohydrate transport
HBJ12_RS00920	COG4213	ABC transporter substrate-binding protein
HBJ12_RS00935	COG4682	membrane
HBJ12_RS00940	COG4682	membrane
HBJ12_RS00945	COG3274	enterobacterial common antigen metabolic process
HBJ12_RS00975	COG1278	Cold shock
HBJ12_RS00980	COG2944	sequence-specific DNA binding
HBJ12_RS00985	COG2814	Major facilitator Superfamily
HBJ12_RS01005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBJ12_RS01015	COG1609	Transcriptional regulator
HBJ12_RS01020	COG2885	chlorophyll binding
HBJ12_RS01025	COG0243	molybdopterin cofactor binding
HBJ12_RS01030	COG0456	acetyltransferase
HBJ12_RS01035	COG2818	Glycosylase
HBJ12_RS01040	COG5571	outer membrane autotransporter
HBJ12_RS01045	COG2223	nitrite transmembrane transporter activity
HBJ12_RS01075	COG0747	negative chemotaxis
HBJ12_RS01080	COG0601	transmembrane transport
HBJ12_RS01085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBJ12_RS01090	COG0444	Belongs to the ABC transporter superfamily
HBJ12_RS01095	COG4608	Belongs to the ABC transporter superfamily
HBJ12_RS01125	COG0457	Tetratricopeptide repeat
HBJ12_RS01140	COG2194	sulfuric ester hydrolase activity
HBJ12_RS01170	COG1215	transferase activity, transferring glycosyl groups
HBJ12_RS01175	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HBJ12_RS01180	COG3118	belongs to the thioredoxin family
HBJ12_RS01180	COG0457	Tetratricopeptide repeat
HBJ12_RS01185	COG2200	EAL domain
HBJ12_RS01185	COG2199	diguanylate cyclase activity
HBJ12_RS01195	COG0612	Peptidase, M16
HBJ12_RS01205	COG2982	Protein involved in outer membrane biogenesis
HBJ12_RS01210	COG0477	Major facilitator Superfamily
HBJ12_RS01215	COG1295	ribonuclease BN
HBJ12_RS01220	COG0583	DNA-binding transcription factor activity
HBJ12_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS01230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBJ12_RS01240	COG1454	alcohol dehydrogenase
HBJ12_RS01250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBJ12_RS01255	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HBJ12_RS01260	COG0671	phosphoesterase, PA-phosphatase related
HBJ12_RS01280	COG0589	response to stress
HBJ12_RS01290	COG0306	phosphate transporter
HBJ12_RS01295	COG2081	HI0933 family
HBJ12_RS01300	COG2239	Acts as a magnesium transporter
HBJ12_RS01310	COG1124	(ABC) transporter
HBJ12_RS01320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBJ12_RS01325	COG0601	transmembrane transport
HBJ12_RS01330	COG0747	negative chemotaxis
HBJ12_RS01340	COG3479	Phenolic acid decarboxylase
HBJ12_RS01380	COG0628	permease
HBJ12_RS01385	COG0477	Major facilitator Superfamily
HBJ12_RS01395	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HBJ12_RS01410	COG3714	YhhN family
HBJ12_RS01420	COG3776	membrane
HBJ12_RS01425	COG0742	ribosomal rna small subunit methyltransferase
HBJ12_RS01430	COG0552	protein localization to endoplasmic reticulum
HBJ12_RS01435	COG2884	Cell division ATP-binding protein ftsE
HBJ12_RS01440	COG2177	Part of the ABC transporter FtsEX involved in
HBJ12_RS01455	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBJ12_RS01465	COG0683	leucine binding
HBJ12_RS01475	COG0683	leucine binding
HBJ12_RS01480	COG0559	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS01530	COG0584	glycerophosphoryl diester phosphodiesterase
HBJ12_RS01540	COG0405	Gamma-glutamyltransferase
HBJ12_RS01545	COG1247	-acetyltransferase
HBJ12_RS01555	COG0673	inositol 2-dehydrogenase activity
HBJ12_RS01560	COG1741	Belongs to the pirin family
HBJ12_RS01565	COG1609	Transcriptional regulator
HBJ12_RS01570	COG3265	gluconokinase activity
HBJ12_RS01575	COG2610	gluconate transmembrane transporter activity
HBJ12_RS01585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HBJ12_RS01610	COG0058	SHG alpha-glucan phosphorylase activity
HBJ12_RS01625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HBJ12_RS01640	COG1349	DNA-binding transcription factor activity
HBJ12_RS01650	COG0058	SHG alpha-glucan phosphorylase activity
HBJ12_RS01655	COG1640	4-alpha-glucanotransferase
HBJ12_RS01660	COG2610	gluconate transmembrane transporter activity
HBJ12_RS01670	COG1040	competence protein
HBJ12_RS01695	COG1918	ferrous iron import across plasma membrane
HBJ12_RS01700	COG2183	response to ionizing radiation
HBJ12_RS01705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HBJ12_RS01730	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HBJ12_RS01735	COG1011	Hydrolase
HBJ12_RS01745	COG0494	nUDIX hydrolase
HBJ12_RS01750	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HBJ12_RS01775	COG4796	Type ii and iii secretion system protein
HBJ12_RS01790	COG3266	domain, Protein
HBJ12_RS01795	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HBJ12_RS01800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HBJ12_RS01825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBJ12_RS01830	COG0402	S-adenosylhomocysteine deaminase activity
HBJ12_RS01835	COG0738	Major facilitator superfamily
HBJ12_RS01860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBJ12_RS01865	COG1289	transmembrane transporter activity
HBJ12_RS01875	COG1765	OsmC-like protein
HBJ12_RS01880	COG3954	Phosphoribulokinase
HBJ12_RS01890	COG0429	hydrolase of the alpha beta-hydrolase fold
HBJ12_RS01895	COG0488	(ABC) transporter
HBJ12_RS01910	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HBJ12_RS01915	COG1047	Peptidyl-prolyl cis-trans
HBJ12_RS01925	COG0545	Peptidyl-prolyl cis-trans isomerase
HBJ12_RS01930	COG2964	Protein conserved in bacteria
HBJ12_RS01985	COG0051	transcription antitermination factor activity, RNA binding
HBJ12_RS02010	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HBJ12_RS02025	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HBJ12_RS02090	COG0201	protein transport
HBJ12_RS02115	COG0202	RNA polymerase activity
HBJ12_RS02130	COG0789	Transcriptional regulator
HBJ12_RS02135	COG3036	rescue of stalled ribosome
HBJ12_RS02165	COG0758	DNA mediated transformation
HBJ12_RS02175	COG0551	DNA topoisomerase type I activity
HBJ12_RS02195	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HBJ12_RS02230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBJ12_RS02235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBJ12_RS02240	COG1309	transcriptional regulator
HBJ12_RS02245	COG0582	viral genome integration into host DNA
HBJ12_RS02260	COG3561	AntA/AntB antirepressor
HBJ12_RS02345	COG1802	Transcriptional regulator
HBJ12_RS02345	COG4626	Terminase
HBJ12_RS02370	COG4145	pantothenate transmembrane transporter activity
HBJ12_RS02375	COG3924	membrane
HBJ12_RS02380	COG0439	Biotin carboxylase
HBJ12_RS02385	COG0511	ligase activity, forming carbon-carbon bonds
HBJ12_RS02410	COG2200	EAL domain
HBJ12_RS02410	COG2199	diguanylate cyclase activity
HBJ12_RS02415	COG1077	Cell shape determining protein MreB Mrl
HBJ12_RS02420	COG1792	Involved in formation and maintenance of cell shape
HBJ12_RS02425	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HBJ12_RS02435	COG1530	ribonuclease E activity
HBJ12_RS02440	COG3164	Protein of unknown function
HBJ12_RS02445	COG0312	modulator of DNA gyrase
HBJ12_RS02450	COG0583	DNA-binding transcription factor activity
HBJ12_RS02465	COG1289	transmembrane transporter activity
HBJ12_RS02470	COG2732	(Barnase) inhibitor
HBJ12_RS02495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBJ12_RS02500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBJ12_RS02505	COG3105	Protein conserved in bacteria
HBJ12_RS02510	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HBJ12_RS02530	COG0625	glutathione transferase activity
HBJ12_RS02535	COG2969	positive regulation of protein catabolic process
HBJ12_RS02545	COG0493	'glutamate synthase
HBJ12_RS02550	COG0070	glutamate synthase
HBJ12_RS02550	COG0069	glutamate synthase activity
HBJ12_RS02550	COG0067	glutamate synthase
HBJ12_RS02555	COG1242	4 iron, 4 sulfur cluster binding
HBJ12_RS02560	COG2271	Major facilitator Superfamily
HBJ12_RS02565	COG1063	alcohol dehydrogenase
HBJ12_RS02570	COG1312	Catalyzes the dehydration of D-mannonate
HBJ12_RS02575	COG5002	protein histidine kinase activity
HBJ12_RS02575	COG2198	Histidine kinase
HBJ12_RS02575	COG0784	Response regulator, receiver
HBJ12_RS02580	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HBJ12_RS02585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBJ12_RS02590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS02600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS02605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HBJ12_RS02610	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HBJ12_RS02615	COG1137	ATPase activity
HBJ12_RS02620	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HBJ12_RS02625	COG3117	lipopolysaccharide transmembrane transporter activity
HBJ12_RS02630	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HBJ12_RS02640	COG0530	calcium, potassium:sodium antiporter activity
HBJ12_RS02645	COG1127	ABC transporter
HBJ12_RS02650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HBJ12_RS02655	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HBJ12_RS02660	COG2854	intermembrane phospholipid transfer
HBJ12_RS02665	COG3113	response to antibiotic
HBJ12_RS02670	COG5007	Belongs to the BolA IbaG family
HBJ12_RS02680	COG3423	Transcriptional regulator
HBJ12_RS02685	COG0142	geranyltranstransferase activity
HBJ12_RS02700	COG0697	spore germination
HBJ12_RS02710	COG2027	D-alanyl-D-alanine carboxypeptidase
HBJ12_RS02720	COG1534	Rna-binding protein
HBJ12_RS02730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBJ12_RS02735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HBJ12_RS02745	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HBJ12_RS02785	COG0195	Participates in both transcription termination and antitermination
HBJ12_RS02830	COG0814	amino acid
HBJ12_RS02835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBJ12_RS02840	COG0826	peptidase U32
HBJ12_RS02845	COG0826	peptidase U32
HBJ12_RS02850	COG3154	lipid carrier protein
HBJ12_RS02855	COG3153	acetyltransferase
HBJ12_RS02870	COG0693	protein deglycase activity
HBJ12_RS02875	COG0702	epimerase
HBJ12_RS02880	COG0701	Predicted permease
HBJ12_RS02885	COG2823	Periplasmic or secreted lipoprotein
HBJ12_RS02905	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HBJ12_RS02920	COG1063	alcohol dehydrogenase
HBJ12_RS02925	COG3775	system Galactitol-specific IIC component
HBJ12_RS02930	COG3414	Phosphotransferase system galactitol-specific IIB component
HBJ12_RS02935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS02945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS02945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS02950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS02950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBJ12_RS02950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBJ12_RS02955	COG1105	Belongs to the carbohydrate kinase PfkB family
HBJ12_RS02965	COG1349	DNA-binding transcription factor activity
HBJ12_RS02970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBJ12_RS02975	COG2721	sulfolactate sulfo-lyase activity
HBJ12_RS02980	COG2271	Major facilitator Superfamily
HBJ12_RS02990	COG2084	Dehydrogenase
HBJ12_RS02995	COG1929	Belongs to the glycerate kinase type-1 family
HBJ12_RS03020	COG1741	Belongs to the pirin family
HBJ12_RS03025	COG0583	DNA-binding transcription factor activity
HBJ12_RS03030	COG3152	Membrane
HBJ12_RS03035	COG0435	Glutathione S-transferase
HBJ12_RS03040	COG2259	Doxx family
HBJ12_RS03050	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HBJ12_RS03055	COG4575	ribosome binding
HBJ12_RS03060	COG1422	Protein of unknown function (DUF1090)
HBJ12_RS03070	COG0586	Pfam SNARE associated Golgi protein
HBJ12_RS03075	COG2186	Transcriptional regulator
HBJ12_RS03080	COG2271	Major facilitator Superfamily
HBJ12_RS03090	COG2721	sulfolactate sulfo-lyase activity
HBJ12_RS03105	COG0861	Integral membrane protein TerC family
HBJ12_RS03110	COG0673	inositol 2-dehydrogenase activity
HBJ12_RS03115	COG1451	nucleotide metabolic process
HBJ12_RS03135	COG1902	pentaerythritol trinitrate reductase activity
HBJ12_RS03135	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBJ12_RS03185	COG1695	Transcriptional regulator
HBJ12_RS03190	COG2375	cellular response to nickel ion
HBJ12_RS03205	COG1461	Dihydroxyacetone kinase
HBJ12_RS03210	COG2376	Dihydroxyacetone kinase
HBJ12_RS03280	COG3247	response to pH
HBJ12_RS03290	COG0784	Response regulator, receiver
HBJ12_RS03290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBJ12_RS03290	COG2198	Histidine kinase
HBJ12_RS03290	COG2205	protein histidine kinase activity
HBJ12_RS03295	COG2197	response regulator
HBJ12_RS03320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBJ12_RS03325	COG0358	DNA primase activity
HBJ12_RS03330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HBJ12_RS03395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HBJ12_RS03410	COG4991	sh3 domain protein
HBJ12_RS03415	COG3025	triphosphatase activity
HBJ12_RS03440	COG2960	long-chain fatty acid transporting porin activity
HBJ12_RS03455	COG3384	dioxygenase
HBJ12_RS03460	COG0754	glutathionylspermidine amidase activity
HBJ12_RS03475	COG0494	nUDIX hydrolase
HBJ12_RS03480	COG3151	Protein conserved in bacteria
HBJ12_RS03485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HBJ12_RS03490	COG3150	esterase
HBJ12_RS03500	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HBJ12_RS03505	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBJ12_RS03510	COG0642	Histidine kinase
HBJ12_RS03520	COG3111	PFAM Bacterial OB fold (BOF) protein
HBJ12_RS03525	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HBJ12_RS03530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBJ12_RS03535	COG0204	Acyl-transferase
HBJ12_RS03540	COG2132	Multicopper oxidase
HBJ12_RS03545	COG1032	radical SAM domain protein
HBJ12_RS03555	COG0656	L-ascorbic acid biosynthetic process
HBJ12_RS03560	COG1979	alcohol dehydrogenase
HBJ12_RS03565	COG2207	Transcriptional regulator
HBJ12_RS03570	COG0586	Pfam SNARE associated Golgi protein
HBJ12_RS03575	COG0626	cystathionine gamma-synthase activity
HBJ12_RS03585	COG0848	biopolymer transport protein
HBJ12_RS03590	COG2211	Major facilitator Superfamily
HBJ12_RS03615	COG0625	glutathione transferase activity
HBJ12_RS03630	COG0754	glutathionylspermidine amidase activity
HBJ12_RS03635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBJ12_RS03655	COG0583	DNA-binding transcription factor activity
HBJ12_RS03660	COG0626	cystathionine gamma-synthase activity
HBJ12_RS03915	COG3423	Transcriptional regulator
HBJ12_RS03925	COG1278	Cold shock
HBJ12_RS03930	COG3423	Transcriptional regulator
HBJ12_RS03995	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HBJ12_RS04005	COG1811	Na channel or pump
HBJ12_RS04010	COG1982	Orn Lys Arg decarboxylase major
HBJ12_RS04015	COG2211	Major facilitator Superfamily
HBJ12_RS04030	COG1194	a g-specific adenine glycosylase
HBJ12_RS04040	COG3171	Protein conserved in bacteria
HBJ12_RS04050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HBJ12_RS04065	COG0762	integral membrane protein
HBJ12_RS04070	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HBJ12_RS04075	COG2805	Type II/IV secretion system protein
HBJ12_RS04095	COG0189	ligase activity
HBJ12_RS04100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBJ12_RS04105	COG2356	endonuclease I
HBJ12_RS04115	COG2814	Major facilitator Superfamily
HBJ12_RS04150	COG2146	nitrite reductase [NAD(P)H] activity
HBJ12_RS04165	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS04170	COG1414	Transcriptional regulator
HBJ12_RS04200	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS04205	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HBJ12_RS04225	COG0501	Belongs to the peptidase M48B family
HBJ12_RS04230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBJ12_RS04245	COG0191	fructose-bisphosphate aldolase activity
HBJ12_RS04250	COG0668	transmembrane transport
HBJ12_RS04260	COG2968	Membrane
HBJ12_RS04275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HBJ12_RS04280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBJ12_RS04300	COG0006	proline dipeptidase activity
HBJ12_RS04305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBJ12_RS04310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBJ12_RS04330	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS04335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HBJ12_RS04355	COG2723	6-phospho-beta-galactosidase activity
HBJ12_RS04360	COG1737	Transcriptional regulator
HBJ12_RS04370	COG1272	protein, Hemolysin III
HBJ12_RS04380	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HBJ12_RS04390	COG0716	FMN binding
HBJ12_RS04395	COG4974	Belongs to the 'phage' integrase family
HBJ12_RS04405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HBJ12_RS04425	COG4942	peptidase
HBJ12_RS04435	COG2814	Major facilitator Superfamily
HBJ12_RS04450	COG0667	Aldo Keto reductase
HBJ12_RS04485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBJ12_RS04490	COG1393	Belongs to the ArsC family
HBJ12_RS04510	COG1289	transmembrane transporter activity
HBJ12_RS04525	COG3592	Divergent 4Fe-4S mono-cluster
HBJ12_RS04530	COG2388	GCN5-related N-acetyl-transferase
HBJ12_RS04540	COG3539	Fimbrial protein
HBJ12_RS04545	COG3539	Fimbrial protein
HBJ12_RS04550	COG3539	Fimbrial protein
HBJ12_RS04555	COG3188	usher protein
HBJ12_RS04560	COG3121	Chaperone
HBJ12_RS04565	COG3539	Fimbrial protein
HBJ12_RS04575	COG4974	Belongs to the 'phage' integrase family
HBJ12_RS04580	COG0582	viral genome integration into host DNA
HBJ12_RS04585	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HBJ12_RS04590	COG1846	Transcriptional regulator
HBJ12_RS04595	COG0697	spore germination
HBJ12_RS04650	COG0667	Aldo Keto reductase
HBJ12_RS04655	COG0814	amino acid
HBJ12_RS04670	COG0183	Belongs to the thiolase family
HBJ12_RS04680	COG0823	Involved in the tonB-independent uptake of proteins
HBJ12_RS04685	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS04725	COG3842	ATPase activity
HBJ12_RS04730	COG0395	ABC-type sugar transport system, permease component
HBJ12_RS04735	COG1175	transmembrane transport
HBJ12_RS04740	COG1917	Cupin 2, conserved barrel domain protein
HBJ12_RS04745	COG1794	racemase activity, acting on amino acids and derivatives
HBJ12_RS04750	COG0583	DNA-binding transcription factor activity
HBJ12_RS04760	COG1609	Transcriptional regulator
HBJ12_RS04765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS04770	COG2723	6-phospho-beta-galactosidase activity
HBJ12_RS04775	COG2186	Transcriptional regulator
HBJ12_RS04785	COG1609	Transcriptional regulator
HBJ12_RS04805	COG0667	Aldo Keto reductase
HBJ12_RS04815	COG0861	Integral membrane protein TerC family
HBJ12_RS04850	COG2165	general secretion pathway protein
HBJ12_RS04855	COG4795	General secretion pathway protein
HBJ12_RS04865	COG4967	type IV pilus modification protein PilV
HBJ12_RS04870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HBJ12_RS04875	COG1025	Belongs to the peptidase M16 family
HBJ12_RS04880	COG1074	ATP-dependent DNA helicase activity
HBJ12_RS04885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBJ12_RS04895	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HBJ12_RS04895	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HBJ12_RS04900	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBJ12_RS04905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HBJ12_RS04935	COG4656	Part of a membrane complex involved in electron transport
HBJ12_RS04940	COG1454	alcohol dehydrogenase
HBJ12_RS04940	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS04970	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HBJ12_RS05135	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HBJ12_RS05140	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HBJ12_RS05145	COG2166	iron-sulfur cluster assembly
HBJ12_RS05150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBJ12_RS05160	COG0583	DNA-binding transcription factor activity
HBJ12_RS05165	COG2363	Small membrane protein
HBJ12_RS05175	COG1349	DNA-binding transcription factor activity
HBJ12_RS05195	COG0738	Major facilitator superfamily
HBJ12_RS05200	COG0235	Class ii aldolase
HBJ12_RS05205	COG1454	alcohol dehydrogenase
HBJ12_RS05225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBJ12_RS05240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBJ12_RS05245	COG2011	ABC-type metal ion transport system permease component
HBJ12_RS05250	COG1464	Belongs to the NlpA lipoprotein family
HBJ12_RS05255	COG0477	Major facilitator Superfamily
HBJ12_RS05265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBJ12_RS05270	COG1760	l-serine dehydratase
HBJ12_RS05275	COG0814	amino acid
HBJ12_RS05280	COG1611	Belongs to the LOG family
HBJ12_RS05295	COG3098	single-species biofilm formation
HBJ12_RS05300	COG0564	pseudouridine synthase activity
HBJ12_RS05305	COG0716	FMN binding
HBJ12_RS05310	COG2271	Major facilitator Superfamily
HBJ12_RS05315	COG4948	Mandelate Racemase Muconate Lactonizing
HBJ12_RS05320	COG4948	Mandelate Racemase Muconate Lactonizing
HBJ12_RS05325	COG1929	Belongs to the glycerate kinase type-1 family
HBJ12_RS05330	COG2205	protein histidine kinase activity
HBJ12_RS05330	COG3437	response regulator, receiver
HBJ12_RS05330	COG4999	Histidine kinase
HBJ12_RS05330	COG3850	Histidine kinase
HBJ12_RS05340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBJ12_RS05345	COG3956	TIGRFAM MazG family protein
HBJ12_RS05365	COG0602	queuosine metabolic process
HBJ12_RS05370	COG0720	synthase
HBJ12_RS05390	COG2234	aminopeptidase activity
HBJ12_RS05450	COG1388	LysM domain
HBJ12_RS05450	COG4942	peptidase
HBJ12_RS05455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBJ12_RS05480	COG0163	prenyltransferase activity
HBJ12_RS05485	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HBJ12_RS05525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBJ12_RS05530	COG4558	Periplasmic binding protein
HBJ12_RS05535	COG3720	iron ion transport
HBJ12_RS05555	COG0679	Auxin Efflux Carrier
HBJ12_RS05570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HBJ12_RS05575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HBJ12_RS05580	COG1121	(ABC) transporter
HBJ12_RS05585	COG0803	Belongs to the bacterial solute-binding protein 9 family
HBJ12_RS05590	COG1609	Transcriptional regulator
HBJ12_RS05595	COG1940	carbohydrate kinase activity
HBJ12_RS05600	COG1447	Phosphotransferase system cellobiose-specific component IIA
HBJ12_RS05605	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS05610	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS05615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS05620	COG4580	involved in the transport of maltose and maltodextrins
HBJ12_RS05630	COG2723	6-phospho-beta-galactosidase activity
HBJ12_RS05640	COG0309	Hydrogenase expression formation protein (HypE)
HBJ12_RS05645	COG0409	Hydrogenase expression formation protein
HBJ12_RS05650	COG0298	carbon dioxide binding
HBJ12_RS05655	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HBJ12_RS05670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBJ12_RS05675	COG0651	ATP synthesis coupled electron transport
HBJ12_RS05680	COG0650	Formate hydrogenlyase subunit 4
HBJ12_RS05685	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HBJ12_RS05685	COG3261	NADH dehydrogenase
HBJ12_RS05690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HBJ12_RS05695	COG3260	NADH ubiquinone oxidoreductase 20
HBJ12_RS05705	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HBJ12_RS05715	COG2723	6-phospho-beta-galactosidase activity
HBJ12_RS05720	COG1263	PTS System
HBJ12_RS05720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBJ12_RS05725	COG1609	Transcriptional regulator
HBJ12_RS05730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBJ12_RS05735	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HBJ12_RS05740	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HBJ12_RS05765	COG1349	DNA-binding transcription factor activity
HBJ12_RS05770	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS05775	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS05785	COG3732	PTS system glucitol sorbitol-specific
HBJ12_RS05790	COG3730	PTS system glucitol sorbitol-specific
HBJ12_RS05795	COG2951	lytic endotransglycosylase activity
HBJ12_RS05800	COG1121	(ABC) transporter
HBJ12_RS05805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HBJ12_RS05810	COG0803	Belongs to the bacterial solute-binding protein 9 family
HBJ12_RS05815	COG1546	Belongs to the CinA family
HBJ12_RS05835	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HBJ12_RS05865	COG2823	Periplasmic or secreted lipoprotein
HBJ12_RS05870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HBJ12_RS05875	COG1238	metal cluster binding
HBJ12_RS05895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HBJ12_RS05900	COG2814	Major facilitator Superfamily
HBJ12_RS05905	COG1566	PFAM secretion protein HlyD family protein
HBJ12_RS05910	COG1846	Transcriptional regulator
HBJ12_RS05920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBJ12_RS05930	COG4176	ABC-type proline glycine betaine transport system permease component
HBJ12_RS05945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBJ12_RS05955	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HBJ12_RS05960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBJ12_RS05965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBJ12_RS05970	COG4575	ribosome binding
HBJ12_RS05985	COG2916	Histone family protein nucleoid-structuring protein H-NS
HBJ12_RS06000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBJ12_RS06005	COG0640	Transcriptional regulator
HBJ12_RS06015	COG0583	DNA-binding transcription factor activity
HBJ12_RS06020	COG3284	Transcriptional regulator
HBJ12_RS06030	COG3539	Fimbrial protein
HBJ12_RS06035	COG3121	Chaperone
HBJ12_RS06055	COG3188	usher protein
HBJ12_RS06065	COG3539	Fimbrial protein
HBJ12_RS06070	COG2197	response regulator
HBJ12_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS06095	COG0235	Class ii aldolase
HBJ12_RS06105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBJ12_RS06140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBJ12_RS06145	COG2207	Transcriptional regulator
HBJ12_RS06145	COG3708	Transcriptional regulator
HBJ12_RS06170	COG4974	Belongs to the 'phage' integrase family
HBJ12_RS06205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HBJ12_RS06250	COG4695	Portal protein
HBJ12_RS06420	COG2867	negative regulation of translational initiation
HBJ12_RS06435	COG0497	DNA recombination
HBJ12_RS06450	COG4536	flavin adenine dinucleotide binding
HBJ12_RS06455	COG4137	Cytochrome C assembly protein
HBJ12_RS06460	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBJ12_RS06495	COG2885	chlorophyll binding
HBJ12_RS06500	COG2199	diguanylate cyclase activity
HBJ12_RS06510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HBJ12_RS06515	COG0287	Prephenate dehydrogenase
HBJ12_RS06515	COG1605	Chorismate mutase
HBJ12_RS06525	COG1605	Chorismate mutase
HBJ12_RS06525	COG0077	Prephenate dehydratase
HBJ12_RS06535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HBJ12_RS06540	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HBJ12_RS06555	COG0542	response to heat
HBJ12_RS06580	COG0477	Major facilitator Superfamily
HBJ12_RS06585	COG5544	Lipoprotein
HBJ12_RS06590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBJ12_RS06600	COG3148	PFAM DTW domain containing protein
HBJ12_RS06605	COG3118	belongs to the thioredoxin family
HBJ12_RS06610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBJ12_RS06625	COG0513	Belongs to the DEAD box helicase family
HBJ12_RS06635	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HBJ12_RS06650	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HBJ12_RS06655	COG3026	antisigma factor binding
HBJ12_RS06660	COG3086	response to oxidative stress
HBJ12_RS06670	COG0681	Belongs to the peptidase S26 family
HBJ12_RS06690	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HBJ12_RS06700	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBJ12_RS06705	COG1737	Transcriptional regulator
HBJ12_RS06710	COG0560	Phosphoserine phosphatase
HBJ12_RS06725	COG0047	phosphoribosylformylglycinamidine synthase activity
HBJ12_RS06725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBJ12_RS06730	COG2205	protein histidine kinase activity
HBJ12_RS06735	COG3170	Tfp pilus assembly protein FimV
HBJ12_RS06740	COG2204	response regulator
HBJ12_RS06745	COG0347	Belongs to the P(II) protein family
HBJ12_RS06750	COG1017	nitric oxide dioxygenase activity
HBJ12_RS06750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBJ12_RS06760	COG2259	Doxx family
HBJ12_RS06765	COG1940	carbohydrate kinase activity
HBJ12_RS06770	COG0457	Tetratricopeptide repeat
HBJ12_RS06775	COG2814	Major facilitator Superfamily
HBJ12_RS06775	COG0477	Major facilitator Superfamily
HBJ12_RS06780	COG2017	converts alpha-aldose to the beta-anomer
HBJ12_RS06785	COG2814	Major facilitator Superfamily
HBJ12_RS06790	COG3711	transcriptional antiterminator
HBJ12_RS06795	COG3683	transport system, periplasmic component
HBJ12_RS06800	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HBJ12_RS06830	COG0822	iron-sulfur transferase activity
HBJ12_RS06850	COG0633	Ferredoxin
HBJ12_RS06855	COG2975	iron-sulfur cluster assembly
HBJ12_RS06875	COG2897	thiosulfate sulfurtransferase activity
HBJ12_RS06880	COG2373	Large extracellular alpha-helical protein
HBJ12_RS06885	COG4953	penicillin-binding protein 1C
HBJ12_RS06915	COG2976	Protein conserved in bacteria
HBJ12_RS06935	COG1645	bacterial-type flagellum-dependent swarming motility
HBJ12_RS06945	COG0516	GMP reductase activity
HBJ12_RS06945	COG0517	IMP dehydrogenase activity
HBJ12_RS06955	COG3119	arylsulfatase activity
HBJ12_RS06960	COG0641	radical SAM
HBJ12_RS06980	COG2200	EAL domain
HBJ12_RS06995	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBJ12_RS07010	COG2723	6-phospho-beta-galactosidase activity
HBJ12_RS07020	COG2233	PERMEase
HBJ12_RS07035	COG1393	Belongs to the ArsC family
HBJ12_RS07040	COG4783	chaperone-mediated protein folding
HBJ12_RS07050	COG0628	permease
HBJ12_RS07055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HBJ12_RS07060	COG2716	regulation of RNA biosynthetic process
HBJ12_RS07070	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HBJ12_RS07080	COG2321	neutral zinc metallopeptidase
HBJ12_RS07085	COG1444	tRNA N-acetyltransferase activity
HBJ12_RS07090	COG0400	carboxylic ester hydrolase activity
HBJ12_RS07105	COG1393	Belongs to the ArsC family
HBJ12_RS07115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBJ12_RS07120	COG0493	'glutamate synthase
HBJ12_RS07120	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBJ12_RS07130	COG5342	invasion associated locus B
HBJ12_RS07135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBJ12_RS07140	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HBJ12_RS07150	COG4810	utilization protein
HBJ12_RS07240	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBJ12_RS07260	COG2837	iron assimilation
HBJ12_RS07270	COG4150	thiosulfate binding
HBJ12_RS07275	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HBJ12_RS07280	COG4208	sulfate ABC transporter
HBJ12_RS07285	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HBJ12_RS07295	COG4319	ketosteroid isomerase
HBJ12_RS07330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HBJ12_RS07350	COG3530	Putative quorum-sensing-regulated virulence factor
HBJ12_RS07355	COG0385	Bile acid
HBJ12_RS07360	COG0583	DNA-binding transcription factor activity
HBJ12_RS07390	COG3415	Transposase
HBJ12_RS07395	COG3415	Transposase
HBJ12_RS07410	COG2199	diguanylate cyclase activity
HBJ12_RS07410	COG2200	EAL domain
HBJ12_RS07415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBJ12_RS07430	COG0667	Aldo Keto reductase
HBJ12_RS07435	COG3961	Belongs to the TPP enzyme family
HBJ12_RS07450	COG3279	Response regulator of the LytR AlgR family
HBJ12_RS07455	COG3275	phosphorelay sensor kinase activity
HBJ12_RS07470	COG0436	Aminotransferase
HBJ12_RS07480	COG2807	transmembrane transport
HBJ12_RS07485	COG0590	tRNA wobble adenosine to inosine editing
HBJ12_RS07490	COG0583	DNA-binding transcription factor activity
HBJ12_RS07510	COG2116	formate transmembrane transporter activity
HBJ12_RS07515	COG2853	Lipoprotein
HBJ12_RS07525	COG3691	Protein conserved in bacteria
HBJ12_RS07540	COG2062	phosphohistidine phosphatase, SixA
HBJ12_RS07565	COG0730	response to heat
HBJ12_RS07570	COG3101	peptidyl-lysine hydroxylation
HBJ12_RS07585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HBJ12_RS07605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HBJ12_RS07615	COG0586	Pfam SNARE associated Golgi protein
HBJ12_RS07625	COG0285	dihydrofolate synthase activity
HBJ12_RS07630	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HBJ12_RS07635	COG1286	toxin biosynthetic process
HBJ12_RS07640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HBJ12_RS07645	COG0163	prenyltransferase activity
HBJ12_RS07670	COG4160	amino acid transport
HBJ12_RS07675	COG4598	ABC transporter
HBJ12_RS07690	COG1090	epimerase
HBJ12_RS07695	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HBJ12_RS07700	COG0625	glutathione transferase activity
HBJ12_RS07705	COG0625	glutathione transferase activity
HBJ12_RS07710	COG0622	Phosphoesterase
HBJ12_RS07715	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HBJ12_RS07720	COG0280	phosphate acetyltransferase
HBJ12_RS07720	COG0857	belongs to the CobB CobQ family
HBJ12_RS07740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HBJ12_RS07745	COG0490	domain, Protein
HBJ12_RS07745	COG0471	metal ion transport
HBJ12_RS07755	COG0436	Aminotransferase
HBJ12_RS07760	COG0583	DNA-binding transcription factor activity
HBJ12_RS07805	COG0839	Belongs to the complex I subunit 6 family
HBJ12_RS07815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBJ12_RS07820	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HBJ12_RS07835	COG2153	protein acetylation
HBJ12_RS07840	COG1169	isochorismate synthase
HBJ12_RS07865	COG0318	PFAM AMP-dependent synthetase and ligase
HBJ12_RS07875	COG5464	transposase or invertase
HBJ12_RS07890	COG1414	Transcriptional regulator
HBJ12_RS07900	COG2271	Major facilitator Superfamily
HBJ12_RS07910	COG0247	lactate metabolic process
HBJ12_RS07920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HBJ12_RS07925	COG2271	Major facilitator Superfamily
HBJ12_RS07930	COG0584	glycerophosphoryl diester phosphodiesterase
HBJ12_RS07935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBJ12_RS07960	COG2205	protein histidine kinase activity
HBJ12_RS07960	COG0784	Response regulator, receiver
HBJ12_RS07970	COG2198	Histidine kinase
HBJ12_RS07970	COG0642	Histidine kinase
HBJ12_RS07985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBJ12_RS07985	COG2169	Transcriptional regulator
HBJ12_RS07990	COG3145	DNA-N1-methyladenine dioxygenase activity
HBJ12_RS07995	COG4615	Cyclic peptide transporter
HBJ12_RS08000	COG2239	Acts as a magnesium transporter
HBJ12_RS08005	COG0659	secondary active sulfate transmembrane transporter activity
HBJ12_RS08020	COG0628	permease
HBJ12_RS08045	COG1349	DNA-binding transcription factor activity
HBJ12_RS08050	COG0494	nUDIX hydrolase
HBJ12_RS08070	COG1061	Type III restriction enzyme res subunit
HBJ12_RS08075	COG1187	pseudouridine synthase activity
HBJ12_RS08080	COG2814	Major facilitator Superfamily
HBJ12_RS08090	COG4172	Belongs to the ABC transporter superfamily
HBJ12_RS08095	COG4239	(ABC) transporter, permease
HBJ12_RS08100	COG4174	ABC transporter (Permease)
HBJ12_RS08105	COG4166	transmembrane transport
HBJ12_RS08110	COG2200	EAL domain
HBJ12_RS08115	COG0791	NLP P60 protein
HBJ12_RS08120	COG0671	phosphoesterase, PA-phosphatase related
HBJ12_RS08125	COG0523	cobalamin synthesis protein
HBJ12_RS08130	COG0246	Mannitol dehydrogenase
HBJ12_RS08135	COG1312	Catalyzes the dehydration of D-mannonate
HBJ12_RS08155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS08155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS08160	COG1105	Belongs to the carbohydrate kinase PfkB family
HBJ12_RS08165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBJ12_RS08165	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HBJ12_RS08165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBJ12_RS08175	COG2855	membrane
HBJ12_RS08180	COG0583	DNA-binding transcription factor activity
HBJ12_RS08185	COG0833	amino acid
HBJ12_RS08195	COG4771	TonB-dependent receptor
HBJ12_RS08210	COG2311	Membrane
HBJ12_RS08225	COG1129	ABC transporter
HBJ12_RS08235	COG2949	membrane
HBJ12_RS08245	COG1346	cytolysis
HBJ12_RS08255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBJ12_RS08260	COG3659	wide pore channel activity
HBJ12_RS08275	COG2723	6-phospho-beta-galactosidase activity
HBJ12_RS08280	COG1538	Outer membrane efflux protein
HBJ12_RS08285	COG0586	Pfam SNARE associated Golgi protein
HBJ12_RS08295	COG1686	Belongs to the peptidase S11 family
HBJ12_RS08305	COG0277	FAD linked oxidase domain protein
HBJ12_RS08310	COG1472	Belongs to the glycosyl hydrolase 3 family
HBJ12_RS08315	COG1732	Glycine betaine
HBJ12_RS08320	COG1174	glycine betaine transport
HBJ12_RS08325	COG1125	glycine betaine transport
HBJ12_RS08330	COG1174	glycine betaine transport
HBJ12_RS08340	COG3275	phosphorelay sensor kinase activity
HBJ12_RS08350	COG4807	Protein conserved in bacteria
HBJ12_RS08370	COG5455	response to cobalt ion
HBJ12_RS08375	COG0583	DNA-binding transcription factor activity
HBJ12_RS08380	COG2252	PERMEase
HBJ12_RS08390	COG0583	DNA-binding transcription factor activity
HBJ12_RS08405	COG0351	phosphomethylpyrimidine kinase
HBJ12_RS08410	COG1830	Aldolase
HBJ12_RS08420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBJ12_RS08445	COG1070	Carbohydrate kinase
HBJ12_RS08455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HBJ12_RS08460	COG4948	Mandelate Racemase Muconate Lactonizing
HBJ12_RS08465	COG0747	negative chemotaxis
HBJ12_RS08470	COG0601	transmembrane transport
HBJ12_RS08475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBJ12_RS08480	COG0444	Belongs to the ABC transporter superfamily
HBJ12_RS08485	COG4608	Belongs to the ABC transporter superfamily
HBJ12_RS08495	COG0826	peptidase U32
HBJ12_RS08500	COG0745	RESPONSE REGULATOR receiver
HBJ12_RS08505	COG2205	protein histidine kinase activity
HBJ12_RS08530	COG1301	dicarboxylic acid transport
HBJ12_RS08550	COG5002	protein histidine kinase activity
HBJ12_RS08555	COG0443	Heat shock 70 kDa protein
HBJ12_RS08560	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HBJ12_RS08575	COG2982	Protein involved in outer membrane biogenesis
HBJ12_RS08580	COG1253	flavin adenine dinucleotide binding
HBJ12_RS08630	COG1088	dTDP-glucose 4,6-dehydratase activity
HBJ12_RS08675	COG2327	Polysaccharide pyruvyl transferase
HBJ12_RS08745	COG4372	Transposase
HBJ12_RS08750	COG3436	PFAM IS66 Orf2 family protein
HBJ12_RS08775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HBJ12_RS08805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBJ12_RS08810	COG0583	DNA-binding transcription factor activity
HBJ12_RS08820	COG0531	amino acid
HBJ12_RS08825	COG0640	Transcriptional regulator
HBJ12_RS08830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HBJ12_RS08835	COG2925	Exonuclease
HBJ12_RS08845	COG3344	reverse transcriptase
HBJ12_RS08855	COG1289	transmembrane transporter activity
HBJ12_RS08875	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HBJ12_RS08885	COG1942	4-Oxalocrotonate Tautomerase
HBJ12_RS08890	COG0583	DNA-binding transcription factor activity
HBJ12_RS08895	COG0095	Lipoate-protein ligase
HBJ12_RS08900	COG0477	Major facilitator Superfamily
HBJ12_RS08910	COG5001	Diguanylate cyclase
HBJ12_RS08910	COG3300	MHYT domain
HBJ12_RS08920	COG3615	Tellurite resistance protein tehB
HBJ12_RS08945	COG3706	GGDEF domain
HBJ12_RS09020	COG2003	Belongs to the UPF0758 family
HBJ12_RS09065	COG3504	Conjugal transfer protein
HBJ12_RS09145	COG4771	TonB-dependent receptor
HBJ12_RS09150	COG1021	2,3-dihydroxybenzoate-AMP ligase
HBJ12_RS09170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBJ12_RS09170	COG2226	methyltransferase
HBJ12_RS09170	COG3433	isochorismatase activity
HBJ12_RS09185	COG1132	(ABC) transporter
HBJ12_RS09190	COG2814	Major facilitator Superfamily
HBJ12_RS09195	COG1169	isochorismate synthase
HBJ12_RS09200	COG0582	viral genome integration into host DNA
HBJ12_RS09210	COG0534	Mate efflux family protein
HBJ12_RS09220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBJ12_RS09240	COG0604	alcohol dehydrogenase
HBJ12_RS09245	COG1309	transcriptional regulator
HBJ12_RS09250	COG0025	NhaP-type Na H and K H
HBJ12_RS09295	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HBJ12_RS09305	COG1418	mRNA catabolic process
HBJ12_RS09310	COG0270	DNA (cytosine-5-)-methyltransferase activity
HBJ12_RS09315	COG3727	T/G mismatch-specific endonuclease activity
HBJ12_RS09320	COG0697	spore germination
HBJ12_RS09325	COG2354	Protein conserved in bacteria
HBJ12_RS09355	COG0366	Alpha amylase catalytic
HBJ12_RS09360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBJ12_RS09370	COG0765	amino acid transport
HBJ12_RS09375	COG1126	abc transporter atp-binding protein
HBJ12_RS09380	COG2197	response regulator
HBJ12_RS09390	COG2197	response regulator
HBJ12_RS09425	COG3318	Belongs to the UPF0149 family
HBJ12_RS09425	COG3012	SEC-C Motif Domain Protein
HBJ12_RS09430	COG0814	amino acid
HBJ12_RS09440	COG1528	Iron-storage protein
HBJ12_RS09455	COG0477	Major facilitator Superfamily
HBJ12_RS09465	COG2211	Major facilitator Superfamily
HBJ12_RS09475	COG1528	Iron-storage protein
HBJ12_RS09485	COG1879	ABC-type sugar transport system periplasmic component
HBJ12_RS09495	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS09520	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HBJ12_RS09530	COG3102	Protein conserved in bacteria
HBJ12_RS09550	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HBJ12_RS09555	COG1801	Protein of unknown function DUF72
HBJ12_RS09560	COG1335	isochorismatase
HBJ12_RS09570	COG0494	nUDIX hydrolase
HBJ12_RS09595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HBJ12_RS09605	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HBJ12_RS09610	COG0739	heme binding
HBJ12_RS09615	COG1560	Kdo2-lipid A biosynthetic process
HBJ12_RS09625	COG1737	Transcriptional regulator
HBJ12_RS09635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HBJ12_RS09640	COG0129	dihydroxy-acid dehydratase activity
HBJ12_RS09645	COG0800	Aldolase
HBJ12_RS09655	COG3141	response to X-ray
HBJ12_RS09660	COG2979	Protein of unknown function (DUF533)
HBJ12_RS09665	COG1770	oligopeptidase
HBJ12_RS09670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBJ12_RS09680	COG2372	response to copper ion
HBJ12_RS09685	COG1276	copper resistance
HBJ12_RS09700	COG2990	Protein conserved in bacteria
HBJ12_RS09725	COG3008	intermembrane lipid transfer
HBJ12_RS09730	COG2995	paraquat-inducible protein a
HBJ12_RS09735	COG1956	GAF domain-containing protein
HBJ12_RS09755	COG2814	Major facilitator Superfamily
HBJ12_RS09760	COG1414	Transcriptional regulator
HBJ12_RS09795	COG0768	penicillin binding
HBJ12_RS09800	COG2226	methyltransferase
HBJ12_RS09815	COG3716	PTS system mannose fructose sorbose family IID component
HBJ12_RS09820	COG3715	PTS system
HBJ12_RS09825	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBJ12_RS09825	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS09830	COG1253	flavin adenine dinucleotide binding
HBJ12_RS09835	COG2200	EAL domain
HBJ12_RS09840	COG1760	l-serine dehydratase
HBJ12_RS09860	COG0251	oxidation-reduction process
HBJ12_RS09865	COG1199	ATP-dependent helicase activity
HBJ12_RS09875	COG3065	identical protein binding
HBJ12_RS09885	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HBJ12_RS09895	COG2894	cell division
HBJ12_RS09910	COG0179	Fumarylacetoacetate (FAA) hydrolase
HBJ12_RS09940	COG2719	SpoVR family
HBJ12_RS09965	COG1619	proteins homologs of microcin C7 resistance protein MccF
HBJ12_RS09975	COG4774	siderophore transport
HBJ12_RS09990	COG2308	Evidence 4 Homologs of previously reported genes of
HBJ12_RS10035	COG0583	DNA-binding transcription factor activity
HBJ12_RS10040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBJ12_RS10055	COG1882	Formate acetyltransferase
HBJ12_RS10090	COG0583	DNA-binding transcription factor activity
HBJ12_RS10120	COG0583	DNA-binding transcription factor activity
HBJ12_RS10135	COG3122	Protein conserved in bacteria
HBJ12_RS10160	COG2885	chlorophyll binding
HBJ12_RS10190	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HBJ12_RS10265	COG0012	GTP binding
HBJ12_RS10285	COG0659	secondary active sulfate transmembrane transporter activity
HBJ12_RS10315	COG2890	protein-(glutamine-N5) methyltransferase activity
HBJ12_RS10335	COG0387	Pfam Sodium calcium exchanger
HBJ12_RS10340	COG4572	Cation transport regulator
HBJ12_RS10345	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HBJ12_RS10355	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HBJ12_RS10360	COG3707	response regulator
HBJ12_RS10365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBJ12_RS10375	COG1116	anion transmembrane transporter activity
HBJ12_RS10380	COG2146	nitrite reductase [NAD(P)H] activity
HBJ12_RS10380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBJ12_RS10385	COG0243	molybdopterin cofactor binding
HBJ12_RS10390	COG4932	domain protein
HBJ12_RS10395	COG2197	response regulator
HBJ12_RS10400	COG3850	Histidine kinase
HBJ12_RS10405	COG2223	nitrite transmembrane transporter activity
HBJ12_RS10415	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBJ12_RS10420	COG1140	nitrate reductase beta subunit
HBJ12_RS10425	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HBJ12_RS10430	COG2181	nitrate reductase activity
HBJ12_RS10440	COG1522	sequence-specific DNA binding
HBJ12_RS10475	COG0788	formyltetrahydrofolate deformylase activity
HBJ12_RS10485	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBJ12_RS10490	COG0745	RESPONSE REGULATOR receiver
HBJ12_RS10495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HBJ12_RS10500	COG2916	Histone family protein nucleoid-structuring protein H-NS
HBJ12_RS10510	COG1435	thymidine kinase activity
HBJ12_RS10515	COG1454	alcohol dehydrogenase
HBJ12_RS10515	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS10525	COG2095	MarC family integral membrane protein
HBJ12_RS10530	COG4166	transmembrane transport
HBJ12_RS10535	COG0601	transmembrane transport
HBJ12_RS10540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBJ12_RS10545	COG0444	Belongs to the ABC transporter superfamily
HBJ12_RS10555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBJ12_RS10575	COG2353	YceI-like domain
HBJ12_RS10585	COG2350	Protein conserved in bacteria
HBJ12_RS10595	COG3001	Fructosamine kinase
HBJ12_RS10605	COG1105	Belongs to the carbohydrate kinase PfkB family
HBJ12_RS10610	COG3137	Salt-induced outer membrane protein
HBJ12_RS10650	COG0072	phenylalanine-tRNA ligase activity
HBJ12_RS10650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBJ12_RS10670	COG0583	DNA-binding transcription factor activity
HBJ12_RS10690	COG0386	Belongs to the glutathione peroxidase family
HBJ12_RS10700	COG0791	NLP P60 protein
HBJ12_RS10710	COG4256	Hemin uptake protein
HBJ12_RS10715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HBJ12_RS10730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBJ12_RS10730	COG0574	Belongs to the PEP-utilizing enzyme family
HBJ12_RS10740	COG0628	permease
HBJ12_RS10745	COG0247	lactate metabolic process
HBJ12_RS10745	COG0277	FAD linked oxidase domain protein
HBJ12_RS10750	COG2050	protein possibly involved in aromatic compounds catabolism
HBJ12_RS10755	COG2261	transglycosylase associated protein
HBJ12_RS10780	COG1120	ATPase activity
HBJ12_RS10785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBJ12_RS10795	COG0583	DNA-binding transcription factor activity
HBJ12_RS10820	COG1304	FMN binding
HBJ12_RS10825	COG1309	transcriptional regulator
HBJ12_RS10845	COG0316	Belongs to the HesB IscA family
HBJ12_RS10850	COG0719	Fe-S assembly protein
HBJ12_RS10855	COG0396	ATPase activity
HBJ12_RS10860	COG0719	Fe-S assembly protein
HBJ12_RS10875	COG1376	ErfK ybiS ycfS ynhG family protein
HBJ12_RS10905	COG1309	transcriptional regulator
HBJ12_RS10910	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HBJ12_RS10910	COG1082	Xylose isomerase domain protein TIM barrel
HBJ12_RS10915	COG2271	Major facilitator Superfamily
HBJ12_RS10920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HBJ12_RS10930	COG1120	ATPase activity
HBJ12_RS10935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBJ12_RS10940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBJ12_RS10945	COG1414	Transcriptional regulator
HBJ12_RS10980	COG2814	Major facilitator Superfamily
HBJ12_RS11000	COG0583	DNA-binding transcription factor activity
HBJ12_RS11005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBJ12_RS11025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBJ12_RS11030	COG1116	anion transmembrane transporter activity
HBJ12_RS11035	COG4774	siderophore transport
HBJ12_RS11040	COG1120	ATPase activity
HBJ12_RS11045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBJ12_RS11050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBJ12_RS11070	COG0765	amino acid transport
HBJ12_RS11075	COG1126	abc transporter atp-binding protein
HBJ12_RS11115	COG3383	formate dehydrogenase (NAD+) activity
HBJ12_RS11120	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HBJ12_RS11130	COG1175	transmembrane transport
HBJ12_RS11160	COG4133	protoheme IX ABC transporter activity
HBJ12_RS11165	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HBJ12_RS11170	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HBJ12_RS11185	COG1138	Cytochrome C-type biogenesis protein
HBJ12_RS11190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HBJ12_RS11195	COG4235	cytochrome complex assembly
HBJ12_RS11195	COG3088	subunit of a heme lyase
HBJ12_RS11235	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS11240	COG2610	gluconate transmembrane transporter activity
HBJ12_RS11245	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBJ12_RS11255	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBJ12_RS11265	COG0583	DNA-binding transcription factor activity
HBJ12_RS11290	COG0277	FAD linked oxidase domain protein
HBJ12_RS11295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBJ12_RS11320	COG0402	S-adenosylhomocysteine deaminase activity
HBJ12_RS11375	COG4608	Belongs to the ABC transporter superfamily
HBJ12_RS11380	COG0444	Belongs to the ABC transporter superfamily
HBJ12_RS11405	COG0346	lactoylglutathione lyase activity
HBJ12_RS11410	COG1349	DNA-binding transcription factor activity
HBJ12_RS11445	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HBJ12_RS11500	COG0307	riboflavin synthase, alpha
HBJ12_RS11505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HBJ12_RS11510	COG2814	Major facilitator Superfamily
HBJ12_RS11515	COG0583	DNA-binding transcription factor activity
HBJ12_RS11530	COG2814	Major facilitator Superfamily
HBJ12_RS11545	COG0791	NLP P60 protein
HBJ12_RS11550	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HBJ12_RS11560	COG0346	lactoylglutathione lyase activity
HBJ12_RS11565	COG1902	pentaerythritol trinitrate reductase activity
HBJ12_RS11570	COG1309	transcriptional regulator
HBJ12_RS11575	COG3313	Fe-S protein
HBJ12_RS11580	COG4989	oxidoreductase activity
HBJ12_RS11585	COG2032	superoxide dismutase activity
HBJ12_RS11590	COG1289	transmembrane transporter activity
HBJ12_RS11595	COG1566	PFAM secretion protein HlyD family protein
HBJ12_RS11610	COG3706	GGDEF domain
HBJ12_RS11625	COG3895	Periplasmic Protein
HBJ12_RS11640	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HBJ12_RS11645	COG0625	glutathione transferase activity
HBJ12_RS11655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBJ12_RS11665	COG4659	FMN binding
HBJ12_RS11700	COG2723	6-phospho-beta-galactosidase activity
HBJ12_RS11710	COG0673	inositol 2-dehydrogenase activity
HBJ12_RS11720	COG2814	Major facilitator Superfamily
HBJ12_RS11740	COG3038	cytochrome b561
HBJ12_RS11760	COG0583	DNA-binding transcription factor activity
HBJ12_RS11765	COG3485	protocatechuate 3,4-dioxygenase
HBJ12_RS11770	COG3485	protocatechuate 3,4-dioxygenase
HBJ12_RS11775	COG5383	Protein conserved in bacteria
HBJ12_RS11780	COG2272	Belongs to the type-B carboxylesterase lipase family
HBJ12_RS11795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBJ12_RS11800	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HBJ12_RS11805	COG1275	C4-dicarboxylate transporter malic acid transport protein
HBJ12_RS11810	COG0500	methyltransferase
HBJ12_RS11825	COG2207	Transcriptional regulator
HBJ12_RS11825	COG3708	Transcriptional regulator
HBJ12_RS11830	COG3135	benzoate transporter
HBJ12_RS11835	COG1396	sequence-specific DNA binding
HBJ12_RS11845	COG0826	peptidase U32
HBJ12_RS11865	COG1294	oxidase, subunit
HBJ12_RS11875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBJ12_RS11880	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HBJ12_RS11885	COG3842	ATPase activity
HBJ12_RS11890	COG1176	ABC-type spermidine putrescine transport system, permease component I
HBJ12_RS11895	COG1177	transmembrane transport
HBJ12_RS11900	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS11935	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS11940	COG0747	negative chemotaxis
HBJ12_RS11950	COG3238	Protein conserved in bacteria
HBJ12_RS11955	COG1247	-acetyltransferase
HBJ12_RS11965	COG2130	NADP-dependent
HBJ12_RS11980	COG3691	Protein conserved in bacteria
HBJ12_RS11985	COG1228	amidohydrolase
HBJ12_RS11990	COG4772	TonB-dependent receptor
HBJ12_RS12015	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HBJ12_RS12020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBJ12_RS12025	COG1473	amidohydrolase
HBJ12_RS12030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBJ12_RS12035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBJ12_RS12045	COG0765	amino acid transport
HBJ12_RS12050	COG1126	abc transporter atp-binding protein
HBJ12_RS12060	COG0625	glutathione transferase activity
HBJ12_RS12070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBJ12_RS12075	COG3842	ATPase activity
HBJ12_RS12080	COG1840	ABC-type Fe3 transport system, periplasmic component
HBJ12_RS12085	COG1178	ABC-type Fe3 transport system permease component
HBJ12_RS12090	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HBJ12_RS12095	COG2181	nitrate reductase activity
HBJ12_RS12100	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HBJ12_RS12105	COG1140	nitrate reductase beta subunit
HBJ12_RS12110	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBJ12_RS12115	COG2223	nitrite transmembrane transporter activity
HBJ12_RS12130	COG1414	Transcriptional regulator
HBJ12_RS12135	COG4948	Mandelate Racemase Muconate Lactonizing
HBJ12_RS12140	COG4829	muconolactone delta-isomerase
HBJ12_RS12145	COG3485	protocatechuate 3,4-dioxygenase
HBJ12_RS12155	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HBJ12_RS12180	COG0437	4 iron, 4 sulfur cluster binding
HBJ12_RS12185	COG2864	formate dehydrogenase
HBJ12_RS12200	COG2326	polyphosphate kinase activity
HBJ12_RS12210	COG2814	Major facilitator Superfamily
HBJ12_RS12220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBJ12_RS12230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBJ12_RS12240	COG0747	negative chemotaxis
HBJ12_RS12245	COG1064	alcohol dehydrogenase
HBJ12_RS12260	COG0488	(ABC) transporter
HBJ12_RS12300	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS12305	COG3729	General stress protein
HBJ12_RS12315	COG3685	Protein conserved in bacteria
HBJ12_RS12325	COG0366	Alpha amylase catalytic
HBJ12_RS12335	COG2323	membrane
HBJ12_RS12345	COG3111	PFAM Bacterial OB fold (BOF) protein
HBJ12_RS12355	COG1764	response to oxidative stress
HBJ12_RS12380	COG3781	membrane
HBJ12_RS12385	COG0243	molybdopterin cofactor binding
HBJ12_RS12390	COG0583	DNA-binding transcription factor activity
HBJ12_RS12395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS12420	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS12425	COG1447	Phosphotransferase system cellobiose-specific component IIA
HBJ12_RS12430	COG2814	Major facilitator Superfamily
HBJ12_RS12435	COG1285	pathogenesis
HBJ12_RS12440	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HBJ12_RS12450	COG0583	DNA-binding transcription factor activity
HBJ12_RS12470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HBJ12_RS12470	COG0519	Catalyzes the synthesis of GMP from XMP
HBJ12_RS12510	COG0596	Alpha beta hydrolase
HBJ12_RS12520	COG2205	protein histidine kinase activity
HBJ12_RS12535	COG0076	glutamate decarboxylase activity
HBJ12_RS12540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBJ12_RS12545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBJ12_RS12550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBJ12_RS12555	COG1116	anion transmembrane transporter activity
HBJ12_RS12560	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBJ12_RS12575	COG0673	inositol 2-dehydrogenase activity
HBJ12_RS12585	COG1609	Transcriptional regulator
HBJ12_RS12590	COG3706	GGDEF domain
HBJ12_RS12595	COG0402	S-adenosylhomocysteine deaminase activity
HBJ12_RS12600	COG1953	Uracil, thiamine, allantoin
HBJ12_RS12640	COG0406	alpha-ribazole phosphatase activity
HBJ12_RS12645	COG1335	isochorismatase
HBJ12_RS12660	COG2207	Transcriptional regulator
HBJ12_RS12675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HBJ12_RS12740	COG0765	amino acid transport
HBJ12_RS12750	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HBJ12_RS12760	COG2070	2-Nitropropane dioxygenase
HBJ12_RS12765	COG0583	DNA-binding transcription factor activity
HBJ12_RS12775	COG1902	pentaerythritol trinitrate reductase activity
HBJ12_RS12780	COG4529	Protein conserved in bacteria
HBJ12_RS12785	COG0477	Major facilitator Superfamily
HBJ12_RS12815	COG2223	nitrite transmembrane transporter activity
HBJ12_RS12825	COG1609	Transcriptional regulator
HBJ12_RS12830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS12840	COG3037	sugar-specific permease SgaT UlaA
HBJ12_RS12845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HBJ12_RS12855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBJ12_RS12860	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HBJ12_RS12860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBJ12_RS12860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBJ12_RS12870	COG1652	LysM domain
HBJ12_RS12895	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBJ12_RS12895	COG0456	acetyltransferase
HBJ12_RS12905	COG0667	Aldo Keto reductase
HBJ12_RS12910	COG0667	Aldo Keto reductase
HBJ12_RS12915	COG3386	PFAM SMP-30 Gluconolaconase
HBJ12_RS12920	COG0667	Aldo Keto reductase
HBJ12_RS12945	COG4977	sequence-specific DNA binding
HBJ12_RS12965	COG4977	sequence-specific DNA binding
HBJ12_RS12970	COG1349	DNA-binding transcription factor activity
HBJ12_RS12985	COG1349	DNA-binding transcription factor activity
HBJ12_RS12990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HBJ12_RS12995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBJ12_RS13000	COG0738	Major facilitator superfamily
HBJ12_RS13045	COG1929	Belongs to the glycerate kinase type-1 family
HBJ12_RS13050	COG3835	regulator
HBJ12_RS13070	COG2186	Transcriptional regulator
HBJ12_RS13075	COG1263	PTS System
HBJ12_RS13075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBJ12_RS13085	COG2814	Major facilitator Superfamily
HBJ12_RS13090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS13090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS13105	COG2819	hydrolase of the alpha beta superfamily
HBJ12_RS13110	COG5001	Diguanylate cyclase
HBJ12_RS13110	COG3300	MHYT domain
HBJ12_RS13145	COG3188	usher protein
HBJ12_RS13155	COG1649	PFAM Uncharacterised BCR, COG1649
HBJ12_RS13160	COG3550	peptidyl-serine autophosphorylation
HBJ12_RS13165	COG1396	sequence-specific DNA binding
HBJ12_RS13170	COG2351	hydroxyisourate hydrolase activity
HBJ12_RS13175	COG3648	Uricase
HBJ12_RS13175	COG3195	allantoin biosynthetic process
HBJ12_RS13180	COG2233	PERMEase
HBJ12_RS13210	COG2207	Transcriptional regulator
HBJ12_RS13225	COG4628	conserved protein (DUF2132)
HBJ12_RS13245	COG2011	ABC-type metal ion transport system permease component
HBJ12_RS13250	COG2070	2-Nitropropane dioxygenase
HBJ12_RS13260	COG0477	Major facilitator Superfamily
HBJ12_RS13330	COG2199	diguanylate cyclase activity
HBJ12_RS13345	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS13350	COG0583	DNA-binding transcription factor activity
HBJ12_RS13360	COG0039	L-malate dehydrogenase activity
HBJ12_RS13365	COG1349	DNA-binding transcription factor activity
HBJ12_RS13370	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HBJ12_RS13375	COG3395	kinase activity
HBJ12_RS13385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBJ12_RS13400	COG2731	YhcH YjgK YiaL family protein
HBJ12_RS13405	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS13435	COG4977	sequence-specific DNA binding
HBJ12_RS13445	COG0697	spore germination
HBJ12_RS13450	COG2814	Major facilitator Superfamily
HBJ12_RS13460	COG0410	ABC transporter
HBJ12_RS13480	COG0683	leucine binding
HBJ12_RS13485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HBJ12_RS13520	COG2223	nitrite transmembrane transporter activity
HBJ12_RS13525	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HBJ12_RS13540	COG1349	DNA-binding transcription factor activity
HBJ12_RS13545	COG2084	Dehydrogenase
HBJ12_RS13550	COG3395	kinase activity
HBJ12_RS13555	COG0235	Class ii aldolase
HBJ12_RS13560	COG3622	Belongs to the hyi family
HBJ12_RS13565	COG2610	gluconate transmembrane transporter activity
HBJ12_RS13570	COG2207	Transcriptional regulator
HBJ12_RS13570	COG3708	Transcriptional regulator
HBJ12_RS13585	COG2200	EAL domain
HBJ12_RS13590	COG1546	Belongs to the CinA family
HBJ12_RS13595	COG0071	Belongs to the small heat shock protein (HSP20) family
HBJ12_RS13610	COG2197	response regulator
HBJ12_RS13625	COG2135	peptidase activity
HBJ12_RS13630	COG2207	Transcriptional regulator
HBJ12_RS13645	COG4221	oxidoreductase activity
HBJ12_RS13650	COG1802	Transcriptional regulator
HBJ12_RS13655	COG0589	response to stress
HBJ12_RS13660	COG0246	Mannitol dehydrogenase
HBJ12_RS13665	COG2271	Major facilitator Superfamily
HBJ12_RS13680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBJ12_RS13695	COG0243	molybdopterin cofactor binding
HBJ12_RS13700	COG0437	4 iron, 4 sulfur cluster binding
HBJ12_RS13705	COG3302	dmso reductase anchor subunit
HBJ12_RS13720	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HBJ12_RS13725	COG1940	carbohydrate kinase activity
HBJ12_RS13730	COG0583	DNA-binding transcription factor activity
HBJ12_RS13735	COG2814	Major facilitator Superfamily
HBJ12_RS13740	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HBJ12_RS13750	COG3591	Belongs to the peptidase S1B family
HBJ12_RS13770	COG0628	permease
HBJ12_RS13800	COG0679	Auxin Efflux Carrier
HBJ12_RS13810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HBJ12_RS13835	COG3290	protein histidine kinase activity
HBJ12_RS13840	COG4565	transcriptional regulatory protein
HBJ12_RS13860	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HBJ12_RS13860	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HBJ12_RS13870	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBJ12_RS13875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBJ12_RS13885	COG0183	Belongs to the thiolase family
HBJ12_RS13890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBJ12_RS13900	COG1414	Transcriptional regulator
HBJ12_RS13905	COG2840	Smr protein MutS2
HBJ12_RS13910	COG0583	DNA-binding transcription factor activity
HBJ12_RS13920	COG1473	amidohydrolase
HBJ12_RS13925	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HBJ12_RS13940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBJ12_RS13955	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HBJ12_RS13960	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HBJ12_RS13975	COG0531	amino acid
HBJ12_RS13985	COG3136	membrane protein required for alginate biosynthesis
HBJ12_RS13990	COG0745	RESPONSE REGULATOR receiver
HBJ12_RS14000	COG2205	protein histidine kinase activity
HBJ12_RS14010	COG0114	fumarate hydratase activity
HBJ12_RS14015	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HBJ12_RS14015	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HBJ12_RS14020	COG1482	cell wall glycoprotein biosynthetic process
HBJ12_RS14025	COG5339	Protein conserved in bacteria
HBJ12_RS14030	COG1609	Transcriptional regulator
HBJ12_RS14035	COG1263	PTS System
HBJ12_RS14035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBJ12_RS14040	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HBJ12_RS14065	COG2391	methyltransferase activity
HBJ12_RS14070	COG0425	Belongs to the sulfur carrier protein TusA family
HBJ12_RS14075	COG5562	phage envelope protein
HBJ12_RS14080	COG0401	homolog of Blt101
HBJ12_RS14085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HBJ12_RS14090	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS14100	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HBJ12_RS14105	COG0477	Major facilitator Superfamily
HBJ12_RS14110	COG1113	amino acid transport
HBJ12_RS14115	COG2988	succinylglutamate desuccinylase activity
HBJ12_RS14120	COG3724	N-succinylarginine dihydrolase activity
HBJ12_RS14125	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS14130	COG3138	arginine N-succinyltransferase
HBJ12_RS14135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBJ12_RS14145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBJ12_RS14150	COG0667	Aldo Keto reductase
HBJ12_RS14155	COG0583	DNA-binding transcription factor activity
HBJ12_RS14180	COG4122	O-methyltransferase activity
HBJ12_RS14185	COG1643	Atp-dependent helicase
HBJ12_RS14200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HBJ12_RS14205	COG3327	negative regulation of DNA-templated transcription, initiation
HBJ12_RS14210	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HBJ12_RS14215	COG0183	Belongs to the thiolase family
HBJ12_RS14220	COG2050	protein possibly involved in aromatic compounds catabolism
HBJ12_RS14225	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBJ12_RS14230	COG1024	Enoyl-CoA hydratase
HBJ12_RS14235	COG1024	Enoyl-CoA hydratase
HBJ12_RS14240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBJ12_RS14245	COG2151	metal-sulfur cluster biosynthetic enzyme
HBJ12_RS14250	COG3396	Phenylacetate-CoA oxygenase
HBJ12_RS14255	COG3460	Phenylacetate-CoA oxygenase
HBJ12_RS14260	COG3396	Phenylacetate-CoA oxygenase
HBJ12_RS14265	COG2030	dehydratase
HBJ12_RS14265	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS14285	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS14290	COG2207	Transcriptional regulator
HBJ12_RS14295	COG3784	Protein of unknown function (DUF1318)
HBJ12_RS14305	COG2911	Protein conserved in bacteria
HBJ12_RS14310	COG0586	Pfam SNARE associated Golgi protein
HBJ12_RS14315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBJ12_RS14320	COG3187	Heat shock protein
HBJ12_RS14325	COG3042	response to heat
HBJ12_RS14330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HBJ12_RS14330	COG1013	pyruvate-flavodoxin oxidoreductase activity
HBJ12_RS14330	COG0674	pyruvate-flavodoxin oxidoreductase activity
HBJ12_RS14330	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HBJ12_RS14335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HBJ12_RS14345	COG0589	response to stress
HBJ12_RS14355	COG0513	Belongs to the DEAD box helicase family
HBJ12_RS14365	COG1349	DNA-binding transcription factor activity
HBJ12_RS14370	COG0673	inositol 2-dehydrogenase activity
HBJ12_RS14385	COG1113	amino acid transport
HBJ12_RS14390	COG1522	sequence-specific DNA binding
HBJ12_RS14400	COG1448	Aminotransferase
HBJ12_RS14405	COG2011	ABC-type metal ion transport system permease component
HBJ12_RS14420	COG0436	Aminotransferase
HBJ12_RS14425	COG0604	alcohol dehydrogenase
HBJ12_RS14455	COG0583	DNA-binding transcription factor activity
HBJ12_RS14475	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS14480	COG1309	transcriptional regulator
HBJ12_RS14485	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS14580	COG2885	chlorophyll binding
HBJ12_RS14695	COG0739	heme binding
HBJ12_RS14695	COG1196	nuclear chromosome segregation
HBJ12_RS14695	COG0741	lytic transglycosylase activity
HBJ12_RS14765	COG3567	Phage-associated protein, HI1409 family
HBJ12_RS14770	COG1783	phage Terminase large subunit
HBJ12_RS14790	COG3772	lysozyme
HBJ12_RS14800	COG0484	heat shock protein binding
HBJ12_RS14905	COG0582	viral genome integration into host DNA
HBJ12_RS14910	COG0693	protein deglycase activity
HBJ12_RS14915	COG1078	dGTPase activity
HBJ12_RS14920	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS14925	COG0583	DNA-binding transcription factor activity
HBJ12_RS14940	COG0656	L-ascorbic acid biosynthetic process
HBJ12_RS14970	COG4166	transmembrane transport
HBJ12_RS14980	COG2866	Carboxypeptidase
HBJ12_RS14990	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HBJ12_RS14995	COG3180	Ammonia monooxygenase
HBJ12_RS15005	COG1486	melibiose metabolic process
HBJ12_RS15010	COG0583	DNA-binding transcription factor activity
HBJ12_RS15020	COG3106	COG3106 Predicted ATPase
HBJ12_RS15030	COG1983	PspC domain protein
HBJ12_RS15040	COG1842	Phage shock protein A
HBJ12_RS15045	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HBJ12_RS15055	COG1473	amidohydrolase
HBJ12_RS15070	COG0702	epimerase
HBJ12_RS15085	COG4171	peptide transport system, permease
HBJ12_RS15100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HBJ12_RS15110	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HBJ12_RS15115	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBJ12_RS15115	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBJ12_RS15130	COG1349	DNA-binding transcription factor activity
HBJ12_RS15140	COG0023	Translation Initiation Factor
HBJ12_RS15150	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HBJ12_RS15155	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HBJ12_RS15160	COG0671	phosphoesterase, PA-phosphatase related
HBJ12_RS15170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HBJ12_RS15195	COG0616	signal peptide processing
HBJ12_RS15205	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS15210	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HBJ12_RS15220	COG0583	DNA-binding transcription factor activity
HBJ12_RS15230	COG0009	L-threonylcarbamoyladenylate synthase
HBJ12_RS15240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HBJ12_RS15245	COG0512	Glutamine amidotransferase of anthranilate synthase
HBJ12_RS15245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HBJ12_RS15250	COG0135	phosphoribosylanthranilate isomerase activity
HBJ12_RS15250	COG0134	indole-3-glycerol-phosphate synthase activity
HBJ12_RS15305	COG4774	siderophore transport
HBJ12_RS15315	COG3047	cAMP biosynthetic process
HBJ12_RS15320	COG0727	PFAM Uncharacterised protein family (UPF0153)
HBJ12_RS15350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HBJ12_RS15355	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS15360	COG1988	membrane-bound metal-dependent
HBJ12_RS15365	COG1823	symporter activity
HBJ12_RS15375	COG0753	catalase activity
HBJ12_RS15385	COG1486	melibiose metabolic process
HBJ12_RS15390	COG1917	Cupin 2, conserved barrel domain protein
HBJ12_RS15390	COG2169	Transcriptional regulator
HBJ12_RS15395	COG1447	Phosphotransferase system cellobiose-specific component IIA
HBJ12_RS15400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS15410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS15415	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HBJ12_RS15425	COG0322	excinuclease ABC activity
HBJ12_RS15430	COG3678	ATP-independent chaperone mediated protein folding
HBJ12_RS15440	COG3724	N-succinylarginine dihydrolase activity
HBJ12_RS15450	COG3138	arginine N-succinyltransferase
HBJ12_RS15460	COG0708	Exodeoxyribonuclease III
HBJ12_RS15465	COG0398	Pfam SNARE associated Golgi protein
HBJ12_RS15470	COG0398	Pfam SNARE associated Golgi protein
HBJ12_RS15475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBJ12_RS15480	COG4134	Bacterial extracellular solute-binding protein
HBJ12_RS15485	COG4135	transport system, permease component
HBJ12_RS15490	COG4136	ATPase activity
HBJ12_RS15495	COG2897	thiosulfate sulfurtransferase activity
HBJ12_RS15500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBJ12_RS15505	COG0494	nUDIX hydrolase
HBJ12_RS15510	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBJ12_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS15515	COG0604	alcohol dehydrogenase
HBJ12_RS15515	COG3321	synthase
HBJ12_RS15520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HBJ12_RS15525	COG0709	Synthesizes selenophosphate from selenide and ATP
HBJ12_RS15540	COG0778	Nitroreductase
HBJ12_RS15545	COG0616	signal peptide processing
HBJ12_RS15550	COG0252	asparaginase activity
HBJ12_RS15555	COG1335	isochorismatase
HBJ12_RS15560	COG2814	Major facilitator Superfamily
HBJ12_RS15565	COG1349	DNA-binding transcription factor activity
HBJ12_RS15570	COG0667	Aldo Keto reductase
HBJ12_RS15575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBJ12_RS15580	COG0191	fructose-bisphosphate aldolase activity
HBJ12_RS15585	COG1063	alcohol dehydrogenase
HBJ12_RS15590	COG2271	Major facilitator Superfamily
HBJ12_RS15595	COG1063	alcohol dehydrogenase
HBJ12_RS15610	COG3139	Protein of unknown function (DUF1315)
HBJ12_RS15630	COG0656	L-ascorbic acid biosynthetic process
HBJ12_RS15635	COG3713	MltA-interacting MipA family protein
HBJ12_RS15640	COG2766	serine protein kinase
HBJ12_RS15655	COG0386	Belongs to the glutathione peroxidase family
HBJ12_RS15680	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS15685	COG0583	DNA-binding transcription factor activity
HBJ12_RS15690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBJ12_RS15695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBJ12_RS15700	COG3344	reverse transcriptase
HBJ12_RS15710	COG0859	PFAM glycosyl transferase family 9
HBJ12_RS15715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBJ12_RS15725	COG2207	Transcriptional regulator
HBJ12_RS15730	COG2807	transmembrane transport
HBJ12_RS15735	COG0504	CTP synthase activity
HBJ12_RS15740	COG1683	Conserved Protein
HBJ12_RS15745	COG3189	MarR family transcriptional regulator
HBJ12_RS15750	COG3042	response to heat
HBJ12_RS15755	COG2199	diguanylate cyclase activity
HBJ12_RS15755	COG2203	Gaf domain
HBJ12_RS15775	COG3182	Iron-regulated membrane protein
HBJ12_RS15785	COG1560	Kdo2-lipid A biosynthetic process
HBJ12_RS15795	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HBJ12_RS15800	COG3706	GGDEF domain
HBJ12_RS15805	COG0583	DNA-binding transcription factor activity
HBJ12_RS15810	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HBJ12_RS15840	COG1294	oxidase, subunit
HBJ12_RS15845	COG1271	oxidase subunit
HBJ12_RS15850	COG3546	catalase activity
HBJ12_RS15855	COG3685	Protein conserved in bacteria
HBJ12_RS15860	COG3685	Protein conserved in bacteria
HBJ12_RS15865	COG3729	General stress protein
HBJ12_RS15870	COG1063	alcohol dehydrogenase
HBJ12_RS15875	COG3813	Protein conserved in bacteria
HBJ12_RS15895	COG0640	Transcriptional regulator
HBJ12_RS15900	COG0538	isocitrate dehydrogenase activity
HBJ12_RS15905	COG1187	pseudouridine synthase activity
HBJ12_RS15925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBJ12_RS15945	COG2205	protein histidine kinase activity
HBJ12_RS15950	COG2850	peptidyl-arginine hydroxylation
HBJ12_RS15970	COG1177	transmembrane transport
HBJ12_RS15985	COG0318	PFAM AMP-dependent synthetase and ligase
HBJ12_RS15995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HBJ12_RS16005	COG4591	ABC-type transport system involved in lipoprotein release permease component
HBJ12_RS16015	COG4591	ABC-type transport system involved in lipoprotein release permease component
HBJ12_RS16025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBJ12_RS16030	COG1388	LysM domain
HBJ12_RS16030	COG1376	ErfK ybiS ycfS ynhG family protein
HBJ12_RS16045	COG1309	transcriptional regulator
HBJ12_RS16060	COG3134	Outer membrane lipoprotein
HBJ12_RS16065	COG1252	NADH dehydrogenase
HBJ12_RS16090	COG5633	Lipoprotein
HBJ12_RS16095	COG0537	adenosine 5'-monophosphoramidase activity
HBJ12_RS16105	COG0084	hydrolase, TatD family'
HBJ12_RS16110	COG0470	DNA polymerase III
HBJ12_RS16120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HBJ12_RS16125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBJ12_RS16130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HBJ12_RS16145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HBJ12_RS16165	COG1399	metal-binding, possibly nucleic acid-binding protein
HBJ12_RS16185	COG1530	ribonuclease E activity
HBJ12_RS16190	COG0583	DNA-binding transcription factor activity
HBJ12_RS16195	COG2814	Major facilitator Superfamily
HBJ12_RS16215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBJ12_RS16260	COG1560	Kdo2-lipid A biosynthetic process
HBJ12_RS16275	COG5645	(Lipo)protein
HBJ12_RS16310	COG3381	protein complex oligomerization
HBJ12_RS16345	COG0583	DNA-binding transcription factor activity
HBJ12_RS16355	COG1335	isochorismatase
HBJ12_RS16365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBJ12_RS16370	COG1702	phosphate starvation-inducible protein PhoH
HBJ12_RS16390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBJ12_RS16400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBJ12_RS16415	COG1309	transcriptional regulator
HBJ12_RS16450	COG2233	PERMEase
HBJ12_RS16460	COG3729	General stress protein
HBJ12_RS16490	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS16505	COG0531	amino acid
HBJ12_RS16510	COG0174	glutamine synthetase
HBJ12_RS16515	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HBJ12_RS16520	COG1917	Cupin 2, conserved barrel domain protein
HBJ12_RS16520	COG1396	sequence-specific DNA binding
HBJ12_RS16525	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS16530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBJ12_RS16535	COG0583	DNA-binding transcription factor activity
HBJ12_RS16540	COG0473	3-isopropylmalate dehydrogenase activity
HBJ12_RS16545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBJ12_RS16550	COG4638	Rieske (2fe-2S)
HBJ12_RS16555	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS16560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBJ12_RS16585	COG0670	Belongs to the BI1 family
HBJ12_RS16600	COG2207	Transcriptional regulator
HBJ12_RS16605	COG1881	PFAM PEBP family protein
HBJ12_RS16620	COG1832	CoA-binding protein
HBJ12_RS16630	COG0210	DNA helicase
HBJ12_RS16635	COG3304	Inner membrane component domain
HBJ12_RS16640	COG1289	transmembrane transporter activity
HBJ12_RS16645	COG3070	regulator of competence-specific genes
HBJ12_RS16665	COG1067	ATP-dependent peptidase activity
HBJ12_RS16675	COG3130	regulation of translation
HBJ12_RS16680	COG3009	Protein conserved in bacteria
HBJ12_RS16685	COG3008	intermembrane lipid transfer
HBJ12_RS16685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HBJ12_RS16690	COG2995	paraquat-inducible protein a
HBJ12_RS16695	COG0488	(ABC) transporter
HBJ12_RS16705	COG0633	Ferredoxin
HBJ12_RS16705	COG3217	Mosc domain protein beta barrel domain protein
HBJ12_RS16720	COG0431	NADPH-dependent FMN reductase
HBJ12_RS16725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBJ12_RS16730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBJ12_RS16735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBJ12_RS16745	COG0308	aminopeptidase N
HBJ12_RS16755	COG1473	amidohydrolase
HBJ12_RS16765	COG0814	amino acid
HBJ12_RS16790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBJ12_RS16790	COG0426	domain, Protein
HBJ12_RS16800	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HBJ12_RS16805	COG1448	Aminotransferase
HBJ12_RS16810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBJ12_RS16815	COG3108	Peptidase M15
HBJ12_RS16820	COG2989	Protein conserved in bacteria
HBJ12_RS16830	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HBJ12_RS16840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HBJ12_RS16845	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HBJ12_RS16850	COG3173	Aminoglycoside phosphotransferase
HBJ12_RS16865	COG3214	Protein conserved in bacteria
HBJ12_RS16880	COG0658	competence protein
HBJ12_RS16880	COG2333	competence protein COMEC
HBJ12_RS16890	COG0539	negative regulation of cytoplasmic translation
HBJ12_RS16910	COG2323	membrane
HBJ12_RS16915	COG1944	ATP diphosphatase activity
HBJ12_RS16920	COG2116	formate transmembrane transporter activity
HBJ12_RS16925	COG1882	Formate acetyltransferase
HBJ12_RS16930	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HBJ12_RS16935	COG0477	Major facilitator Superfamily
HBJ12_RS16940	COG3302	dmso reductase anchor subunit
HBJ12_RS16945	COG0437	4 iron, 4 sulfur cluster binding
HBJ12_RS16950	COG0243	molybdopterin cofactor binding
HBJ12_RS16960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HBJ12_RS16970	COG1178	ABC-type Fe3 transport system permease component
HBJ12_RS16970	COG1674	ftsk spoiiie
HBJ12_RS16980	COG0492	ferredoxin-NADP+ reductase activity
HBJ12_RS16985	COG4988	ABC transporter
HBJ12_RS16990	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HBJ12_RS17005	COG0542	response to heat
HBJ12_RS17015	COG1278	Cold shock
HBJ12_RS17025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBJ12_RS17030	COG3593	DNA synthesis involved in DNA repair
HBJ12_RS17040	COG2431	L-lysine efflux transmembrane transporter activity
HBJ12_RS17050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBJ12_RS17060	COG0028	Belongs to the TPP enzyme family
HBJ12_RS17065	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HBJ12_RS17070	COG0702	epimerase
HBJ12_RS17075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBJ12_RS17080	COG3023	N-Acetylmuramoyl-L-alanine amidase
HBJ12_RS17085	COG3706	GGDEF domain
HBJ12_RS17085	COG2203	Gaf domain
HBJ12_RS17085	COG5001	Diguanylate cyclase
HBJ12_RS17085	COG4251	negative regulation of phosphorylation
HBJ12_RS17095	COG1126	abc transporter atp-binding protein
HBJ12_RS17100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBJ12_RS17105	COG4215	(ABC) transporter
HBJ12_RS17110	COG4160	amino acid transport
HBJ12_RS17115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBJ12_RS17120	COG5002	protein histidine kinase activity
HBJ12_RS17125	COG0745	RESPONSE REGULATOR receiver
HBJ12_RS17140	COG1177	transmembrane transport
HBJ12_RS17145	COG1176	ABC-type spermidine putrescine transport system, permease component I
HBJ12_RS17150	COG3842	ATPase activity
HBJ12_RS17155	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HBJ12_RS17350	COG4695	Portal protein
HBJ12_RS17390	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HBJ12_RS17430	COG3344	reverse transcriptase
HBJ12_RS17435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HBJ12_RS17440	COG3226	Transcriptional regulator
HBJ12_RS17445	COG0738	Major facilitator superfamily
HBJ12_RS17450	COG0561	phosphatase activity
HBJ12_RS17455	COG2814	Major facilitator Superfamily
HBJ12_RS17460	COG0671	phosphoesterase, PA-phosphatase related
HBJ12_RS17465	COG1349	DNA-binding transcription factor activity
HBJ12_RS17470	COG1686	Belongs to the peptidase S11 family
HBJ12_RS17480	COG0625	glutathione transferase activity
HBJ12_RS17485	COG2133	pyrroloquinoline quinone binding
HBJ12_RS17495	COG2223	nitrite transmembrane transporter activity
HBJ12_RS17515	COG0747	negative chemotaxis
HBJ12_RS17530	COG0303	'Molybdopterin
HBJ12_RS17535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HBJ12_RS17540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HBJ12_RS17545	COG1882	Formate acetyltransferase
HBJ12_RS17550	COG0561	phosphatase activity
HBJ12_RS17560	COG1609	Transcriptional regulator
HBJ12_RS17565	COG2271	Major facilitator Superfamily
HBJ12_RS17575	COG0488	(ABC) transporter
HBJ12_RS17580	COG2365	Tyrosine phosphatase family
HBJ12_RS17585	COG1376	ErfK ybiS ycfS ynhG family protein
HBJ12_RS17590	COG2188	Transcriptional regulator
HBJ12_RS17595	COG2723	6-phospho-beta-galactosidase activity
HBJ12_RS17600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBJ12_RS17605	COG1321	iron dependent repressor
HBJ12_RS17615	COG2194	sulfuric ester hydrolase activity
HBJ12_RS17620	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HBJ12_RS17635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBJ12_RS17640	COG0765	amino acid transport
HBJ12_RS17645	COG1126	abc transporter atp-binding protein
HBJ12_RS17650	COG0668	transmembrane transport
HBJ12_RS17660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBJ12_RS17670	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HBJ12_RS17680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HBJ12_RS17685	COG1199	ATP-dependent helicase activity
HBJ12_RS17690	COG0513	Belongs to the DEAD box helicase family
HBJ12_RS17695	COG3958	Transketolase
HBJ12_RS17700	COG3959	Transketolase, thiamine diphosphate binding domain
HBJ12_RS17705	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS17710	COG2271	Major facilitator Superfamily
HBJ12_RS17720	COG0583	DNA-binding transcription factor activity
HBJ12_RS17725	COG1309	transcriptional regulator
HBJ12_RS17730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBJ12_RS17735	COG1131	(ABC) transporter
HBJ12_RS17740	COG0842	Transport permease protein
HBJ12_RS17745	COG0842	Transport permease protein
HBJ12_RS17755	COG3568	Endonuclease Exonuclease Phosphatase
HBJ12_RS17760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBJ12_RS17765	COG0392	lysyltransferase activity
HBJ12_RS17770	COG0670	Belongs to the BI1 family
HBJ12_RS17775	COG0314	molybdopterin synthase activity
HBJ12_RS17780	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HBJ12_RS17790	COG0521	Mo-molybdopterin cofactor biosynthetic process
HBJ12_RS17810	COG0745	RESPONSE REGULATOR receiver
HBJ12_RS17815	COG0642	Histidine kinase
HBJ12_RS17840	COG2226	methyltransferase
HBJ12_RS17855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HBJ12_RS17860	COG1881	PFAM PEBP family protein
HBJ12_RS17900	COG4677	pectinesterase activity
HBJ12_RS17935	COG0789	Transcriptional regulator
HBJ12_RS17940	COG2200	EAL domain
HBJ12_RS17965	COG0561	phosphatase activity
HBJ12_RS17970	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HBJ12_RS17975	COG4149	molybdate abc transporter
HBJ12_RS17980	COG0725	ABC transporter, periplasmic molybdate-binding protein
HBJ12_RS17990	COG2005	Transcriptional regulator
HBJ12_RS17990	COG3585	molybdate ion transport
HBJ12_RS17995	COG1119	ATPase activity
HBJ12_RS18005	COG1085	galactose-1-phosphate uridylyltransferase
HBJ12_RS18015	COG2017	converts alpha-aldose to the beta-anomer
HBJ12_RS18025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HBJ12_RS18040	COG3201	nicotinamide mononucleotide transporter
HBJ12_RS18045	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HBJ12_RS18090	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HBJ12_RS18095	COG2885	chlorophyll binding
HBJ12_RS18105	COG3064	Membrane
HBJ12_RS18110	COG0848	biopolymer transport protein
HBJ12_RS18115	COG0811	peptide transport
HBJ12_RS18120	COG0824	Thioesterase
HBJ12_RS18125	COG3790	cyd operon protein YbgE
HBJ12_RS18130	COG4890	Cyd operon protein YbgT
HBJ12_RS18135	COG1294	oxidase, subunit
HBJ12_RS18140	COG1271	oxidase subunit
HBJ12_RS18145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HBJ12_RS18155	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBJ12_RS18160	COG0567	Dehydrogenase, E1 component
HBJ12_RS18165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HBJ12_RS18170	COG1053	succinate dehydrogenase
HBJ12_RS18175	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HBJ12_RS18180	COG2009	succinate dehydrogenase
HBJ12_RS18215	COG1984	allophanate hydrolase subunit 2
HBJ12_RS18220	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HBJ12_RS18235	COG0415	Belongs to the DNA photolyase family
HBJ12_RS18265	COG2205	protein histidine kinase activity
HBJ12_RS18270	COG0745	RESPONSE REGULATOR receiver
HBJ12_RS18280	COG0033	Phosphoglucomutase
HBJ12_RS18290	COG0596	Alpha beta hydrolase
HBJ12_RS18305	COG0735	belongs to the Fur family
HBJ12_RS18345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HBJ12_RS18350	COG1846	Transcriptional regulator
HBJ12_RS18350	COG1940	carbohydrate kinase activity
HBJ12_RS18355	COG0647	UMP catabolic process
HBJ12_RS18360	COG0367	asparagine synthase
HBJ12_RS18400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBJ12_RS18410	COG1702	phosphate starvation-inducible protein PhoH
HBJ12_RS18420	COG4535	Mg2 and Co2 transporter CorC
HBJ12_RS18435	COG0765	amino acid transport
HBJ12_RS18440	COG0765	amino acid transport
HBJ12_RS18445	COG1126	abc transporter atp-binding protein
HBJ12_RS18460	COG2888	peptidyl-tyrosine sulfation
HBJ12_RS18475	COG1466	dna polymerase III delta subunit
HBJ12_RS18490	COG0799	negative regulation of ribosome biogenesis
HBJ12_RS18500	COG0768	penicillin binding
HBJ12_RS18505	COG0772	Belongs to the SEDS family
HBJ12_RS18510	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HBJ12_RS18515	COG1686	Belongs to the peptidase S11 family
HBJ12_RS18530	COG0583	DNA-binding transcription factor activity
HBJ12_RS18545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBJ12_RS18565	COG3069	C4-dicarboxylate transmembrane transporter activity
HBJ12_RS18570	COG3719	Belongs to the RNase T2 family
HBJ12_RS18575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HBJ12_RS18595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBJ12_RS18600	COG0583	DNA-binding transcription factor activity
HBJ12_RS18605	COG3969	phosphoadenosine phosphosulfate
HBJ12_RS18610	COG1475	DNA binding
HBJ12_RS18615	COG0436	Aminotransferase
HBJ12_RS18640	COG1129	ABC transporter
HBJ12_RS18645	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS18650	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS18660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HBJ12_RS18675	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HBJ12_RS18685	COG0402	S-adenosylhomocysteine deaminase activity
HBJ12_RS18695	COG0483	inositol monophosphate 1-phosphatase activity
HBJ12_RS18700	COG2271	Major facilitator Superfamily
HBJ12_RS18730	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS18735	COG1129	ABC transporter
HBJ12_RS18740	COG0371	Dehydrogenase
HBJ12_RS18745	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS18760	COG2879	small protein
HBJ12_RS18765	COG1966	Carbon starvation protein
HBJ12_RS18775	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS18780	COG3433	isochorismatase activity
HBJ12_RS18780	COG1535	isochorismatase
HBJ12_RS18785	COG1021	2,3-dihydroxybenzoate-AMP ligase
HBJ12_RS18790	COG1169	isochorismate synthase
HBJ12_RS18795	COG4592	Periplasmic binding protein
HBJ12_RS18805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBJ12_RS18810	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBJ12_RS18815	COG1120	ATPase activity
HBJ12_RS18820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBJ12_RS18820	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HBJ12_RS18825	COG3251	PFAM MbtH domain protein
HBJ12_RS18830	COG2382	esterase
HBJ12_RS18835	COG4771	TonB-dependent receptor
HBJ12_RS18840	COG2977	Belongs to the P-Pant transferase superfamily
HBJ12_RS18845	COG3958	Transketolase
HBJ12_RS18850	COG3959	Transketolase, thiamine diphosphate binding domain
HBJ12_RS18855	COG2390	Transcriptional regulator
HBJ12_RS18860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBJ12_RS18865	COG1879	ABC-type sugar transport system periplasmic component
HBJ12_RS18875	COG1129	ABC transporter
HBJ12_RS18880	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS18890	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS18900	COG0583	DNA-binding transcription factor activity
HBJ12_RS18905	COG0668	transmembrane transport
HBJ12_RS18915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBJ12_RS18940	COG0747	negative chemotaxis
HBJ12_RS18945	COG0601	transmembrane transport
HBJ12_RS18950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBJ12_RS18955	COG0444	Belongs to the ABC transporter superfamily
HBJ12_RS18960	COG4608	Belongs to the ABC transporter superfamily
HBJ12_RS18965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HBJ12_RS18970	COG4221	oxidoreductase activity
HBJ12_RS18980	COG4215	(ABC) transporter
HBJ12_RS18985	COG0765	amino acid transport
HBJ12_RS18990	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HBJ12_RS19005	COG0697	spore germination
HBJ12_RS19015	COG3698	Phosphodiester glycosidase
HBJ12_RS19060	COG2315	Protein conserved in bacteria
HBJ12_RS19065	COG0778	Nitroreductase
HBJ12_RS19075	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBJ12_RS19085	COG3716	PTS system mannose fructose sorbose family IID component
HBJ12_RS19090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HBJ12_RS19095	COG2222	sugar isomerase
HBJ12_RS19100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HBJ12_RS19100	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HBJ12_RS19115	COG0477	Major facilitator Superfamily
HBJ12_RS19120	COG0668	transmembrane transport
HBJ12_RS19150	COG3188	usher protein
HBJ12_RS19165	COG2771	luxR family
HBJ12_RS19175	COG0673	inositol 2-dehydrogenase activity
HBJ12_RS19185	COG2211	Major facilitator Superfamily
HBJ12_RS19190	COG1113	amino acid transport
HBJ12_RS19205	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS19210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBJ12_RS19220	COG0531	amino acid
HBJ12_RS19265	COG0667	Aldo Keto reductase
HBJ12_RS19270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBJ12_RS19275	COG1473	amidohydrolase
HBJ12_RS19305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBJ12_RS19310	COG1120	ATPase activity
HBJ12_RS19315	COG1566	PFAM secretion protein HlyD family protein
HBJ12_RS19360	COG4211	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS19365	COG1129	ABC transporter
HBJ12_RS19380	COG0673	inositol 2-dehydrogenase activity
HBJ12_RS19410	COG3104	oligopeptide transport
HBJ12_RS19415	COG1982	Orn Lys Arg decarboxylase major
HBJ12_RS19420	COG0531	amino acid
HBJ12_RS19425	COG3710	Transcriptional regulator
HBJ12_RS19435	COG1560	Kdo2-lipid A biosynthetic process
HBJ12_RS19450	COG3188	usher protein
HBJ12_RS19455	COG3121	Chaperone
HBJ12_RS19460	COG3539	Fimbrial protein
HBJ12_RS19615	COG0582	viral genome integration into host DNA
HBJ12_RS19630	COG2501	S4 domain
HBJ12_RS19640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBJ12_RS19655	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HBJ12_RS19660	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBJ12_RS19680	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HBJ12_RS19685	COG4181	ATPase activity
HBJ12_RS19690	COG2755	lipolytic protein G-D-S-L family
HBJ12_RS19695	COG0300	oxidoreductase activity
HBJ12_RS19700	COG3118	belongs to the thioredoxin family
HBJ12_RS19705	COG0390	transport system, permease component
HBJ12_RS19710	COG4619	ABC transporter
HBJ12_RS19715	COG0330	HflC and HflK could
HBJ12_RS19720	COG1585	Membrane protein implicated in regulation of membrane protease activity
HBJ12_RS19735	COG3735	TraB family
HBJ12_RS19740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBJ12_RS19750	COG2223	nitrite transmembrane transporter activity
HBJ12_RS19755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBJ12_RS19755	COG4651	solute:proton antiporter activity
HBJ12_RS19760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBJ12_RS19800	COG2832	Protein of unknown function (DUF454)
HBJ12_RS19805	COG3923	Primosomal replication protein n
HBJ12_RS19815	COG5464	transposase or invertase
HBJ12_RS19820	COG3264	Mechanosensitive ion channel
HBJ12_RS19820	COG1196	nuclear chromosome segregation
HBJ12_RS19825	COG1309	transcriptional regulator
HBJ12_RS19830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBJ12_RS19835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBJ12_RS19850	COG0110	maltose O-acetyltransferase activity
HBJ12_RS19900	COG1874	Beta-galactosidase
HBJ12_RS19905	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HBJ12_RS19910	COG3833	ABC-type maltose transport systems, permease component
HBJ12_RS19915	COG1175	transmembrane transport
HBJ12_RS19920	COG2182	Extracellular solute-binding protein
HBJ12_RS19930	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HBJ12_RS19945	COG2364	Membrane
HBJ12_RS19975	COG3695	enzyme binding
HBJ12_RS19980	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HBJ12_RS19985	COG1946	Acyl-CoA thioesterase
HBJ12_RS19990	COG0004	ammonium transporteR
HBJ12_RS19995	COG0347	Belongs to the P(II) protein family
HBJ12_RS20000	COG1132	(ABC) transporter
HBJ12_RS20005	COG1132	(ABC) transporter
HBJ12_RS20010	COG1522	sequence-specific DNA binding
HBJ12_RS20025	COG4533	DNA binding
HBJ12_RS20035	COG0824	Thioesterase
HBJ12_RS20040	COG1555	photosystem II stabilization
HBJ12_RS20045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBJ12_RS20050	COG0776	regulation of translation
HBJ12_RS20055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HBJ12_RS20075	COG0271	Belongs to the BolA IbaG family
HBJ12_RS20080	COG3056	Lipoprotein
HBJ12_RS20085	COG2223	nitrite transmembrane transporter activity
HBJ12_RS20090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HBJ12_RS20095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HBJ12_RS20100	COG1845	cytochrome c oxidase, subunit III
HBJ12_RS20105	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HBJ12_RS20120	COG1414	Transcriptional regulator
HBJ12_RS20125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HBJ12_RS20130	COG1053	succinate dehydrogenase
HBJ12_RS20140	COG1053	succinate dehydrogenase
HBJ12_RS20155	COG0673	inositol 2-dehydrogenase activity
HBJ12_RS20160	COG2814	Major facilitator Superfamily
HBJ12_RS20170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBJ12_RS20175	COG0693	protein deglycase activity
HBJ12_RS20195	COG0142	geranyltranstransferase activity
HBJ12_RS20205	COG0667	Aldo Keto reductase
HBJ12_RS20210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HBJ12_RS20230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBJ12_RS20230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBJ12_RS20240	COG4238	major outer membrane lipoprotein
HBJ12_RS20260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBJ12_RS20265	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBJ12_RS20270	COG1862	Preprotein translocase
HBJ12_RS20295	COG0450	alkyl hydroperoxide reductase
HBJ12_RS20305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS20320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBJ12_RS20330	COG1228	amidohydrolase
HBJ12_RS20340	COG1335	isochorismatase
HBJ12_RS20345	COG0583	DNA-binding transcription factor activity
HBJ12_RS20350	COG0366	Alpha amylase catalytic
HBJ12_RS20375	COG0420	3'-5' exonuclease activity
HBJ12_RS20380	COG0419	ATPase involved in DNA repair
HBJ12_RS20385	COG1940	carbohydrate kinase activity
HBJ12_RS20400	COG4126	flavin adenine dinucleotide binding
HBJ12_RS20410	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HBJ12_RS20415	COG3416	Protein conserved in bacteria
HBJ12_RS20425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBJ12_RS20435	COG1785	Belongs to the alkaline phosphatase family
HBJ12_RS20475	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HBJ12_RS20480	COG1335	isochorismatase
HBJ12_RS20485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HBJ12_RS20490	COG0113	porphobilinogen synthase activity
HBJ12_RS20500	COG2175	clavaminate synthase activity
HBJ12_RS20505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBJ12_RS20510	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HBJ12_RS20515	COG4521	taurine ABC transporter
HBJ12_RS20520	COG2040	homocysteine
HBJ12_RS20525	COG0833	amino acid
HBJ12_RS20540	COG4303	Ethanolamine ammonia lyase large subunit
HBJ12_RS20545	COG4302	ethanolamine ammonia-lyase activity
HBJ12_RS20585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBJ12_RS20590	COG1126	abc transporter atp-binding protein
HBJ12_RS20595	COG0765	amino acid transport
HBJ12_RS20600	COG0765	amino acid transport
HBJ12_RS20615	COG3188	usher protein
HBJ12_RS20640	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HBJ12_RS20650	COG3639	organic phosphonate transmembrane transporter activity
HBJ12_RS20670	COG0791	NLP P60 protein
HBJ12_RS20695	COG0582	viral genome integration into host DNA
HBJ12_RS20700	COG1192	Involved in chromosome partitioning
HBJ12_RS20760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HBJ12_RS20765	COG0022	dehydrogenase e1 component
HBJ12_RS20770	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBJ12_RS20775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBJ12_RS20795	COG1070	Carbohydrate kinase
HBJ12_RS20800	COG1028	Short-chain dehydrogenase reductase Sdr
HBJ12_RS20805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HBJ12_RS20810	COG3775	system Galactitol-specific IIC component
HBJ12_RS20815	COG0625	glutathione transferase activity
HBJ12_RS20820	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HBJ12_RS20835	COG0579	oxidoreductase
HBJ12_RS20840	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS20845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBJ12_RS20850	COG1113	amino acid transport
HBJ12_RS20855	COG1802	Transcriptional regulator
HBJ12_RS20875	COG2195	Cleaves the N-terminal amino acid of tripeptides
HBJ12_RS20880	COG0454	-acetyltransferase
HBJ12_RS20895	COG2991	Protein conserved in bacteria
HBJ12_RS20910	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HBJ12_RS20915	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HBJ12_RS20930	COG3034	peptidoglycan biosynthetic process
HBJ12_RS20935	COG0121	glutamine amidotransferase
HBJ12_RS20945	COG1960	acyl-CoA dehydrogenase activity
HBJ12_RS20950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBJ12_RS20960	COG0583	DNA-binding transcription factor activity
HBJ12_RS20970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBJ12_RS20980	COG2226	methyltransferase
HBJ12_RS20990	COG0741	lytic transglycosylase activity
HBJ12_RS20990	COG1388	LysM domain
HBJ12_RS20995	COG2226	methyltransferase
HBJ12_RS21005	COG2814	Major facilitator Superfamily
HBJ12_RS21010	COG0583	DNA-binding transcription factor activity
HBJ12_RS21015	COG0656	L-ascorbic acid biosynthetic process
HBJ12_RS21050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HBJ12_RS21060	COG2011	ABC-type metal ion transport system permease component
HBJ12_RS21065	COG1464	Belongs to the NlpA lipoprotein family
HBJ12_RS21075	COG1720	tRNA m6t6A37 methyltransferase activity
HBJ12_RS21085	COG0791	NLP P60 protein
HBJ12_RS21090	COG3015	lipoprotein NlpE involved in copper resistance
HBJ12_RS21095	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HBJ12_RS21110	COG4568	rho-dependent transcription termination
HBJ12_RS21120	COG0346	lactoylglutathione lyase activity
HBJ12_RS21125	COG1982	Orn Lys Arg decarboxylase major
HBJ12_RS21165	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HBJ12_RS21175	COG0750	zinc metalloprotease
HBJ12_RS21180	COG0575	Belongs to the CDS family
HBJ12_RS21190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HBJ12_RS21215	COG0024	Methionine aminopeptidase
HBJ12_RS21220	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HBJ12_RS21235	COG3835	regulator
HBJ12_RS21240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBJ12_RS21260	COG2860	membrane
HBJ12_RS21280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBJ12_RS21285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBJ12_RS21290	COG1120	ATPase activity
HBJ12_RS21295	COG4774	siderophore transport
HBJ12_RS21300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBJ12_RS21395	COG1643	Atp-dependent helicase
HBJ12_RS21400	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HBJ12_RS21420	COG0617	tRNA 3'-terminal CCA addition
HBJ12_RS21425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HBJ12_RS21445	COG0726	polysaccharide deacetylase
HBJ12_RS21450	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS21455	COG0842	Transport permease protein
HBJ12_RS21460	COG1131	(ABC) transporter
HBJ12_RS21465	COG0288	reversible hydration of carbon dioxide
HBJ12_RS21480	COG4993	Dehydrogenase
HBJ12_RS21485	COG2132	Multicopper oxidase
HBJ12_RS21545	COG3064	Membrane
HBJ12_RS21560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBJ12_RS21565	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBJ12_RS21570	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HBJ12_RS21575	COG2186	Transcriptional regulator
HBJ12_RS21580	COG1113	amino acid transport
HBJ12_RS21585	COG2211	Major facilitator Superfamily
HBJ12_RS21590	COG3940	Belongs to the glycosyl hydrolase 43 family
HBJ12_RS21595	COG3725	Membrane protein required for beta-lactamase induction
HBJ12_RS21600	COG3023	N-Acetylmuramoyl-L-alanine amidase
HBJ12_RS21610	COG4969	Belongs to the N-Me-Phe pilin family
HBJ12_RS21615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HBJ12_RS21620	COG1459	type II secretion system
HBJ12_RS21645	COG0494	nUDIX hydrolase
HBJ12_RS21665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBJ12_RS21670	COG0849	cell division
HBJ12_RS21695	COG0772	Belongs to the SEDS family
HBJ12_RS21710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HBJ12_RS21715	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HBJ12_RS21720	COG0768	penicillin binding
HBJ12_RS21740	COG1609	Transcriptional regulator
HBJ12_RS21750	COG0028	Belongs to the TPP enzyme family
HBJ12_RS21795	COG0738	Major facilitator superfamily
HBJ12_RS21805	COG0583	DNA-binding transcription factor activity
HBJ12_RS21810	COG2271	Major facilitator Superfamily
HBJ12_RS21815	COG2814	Major facilitator Superfamily
HBJ12_RS21835	COG1178	ABC-type Fe3 transport system permease component
HBJ12_RS21845	COG0586	Pfam SNARE associated Golgi protein
HBJ12_RS21865	COG0235	Class ii aldolase
HBJ12_RS21870	COG0417	DNA replication proofreading
HBJ12_RS21880	COG0564	pseudouridine synthase activity
HBJ12_RS21890	COG3493	citrate carrier protein
HBJ12_RS21905	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HBJ12_RS21910	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HBJ12_RS21920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HBJ12_RS21965	COG0505	Belongs to the CarA family
HBJ12_RS22030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HBJ12_RS22055	COG1047	Peptidyl-prolyl cis-trans
HBJ12_RS22070	COG0196	riboflavin kinase activity
HBJ12_RS22080	COG0583	DNA-binding transcription factor activity
HBJ12_RS22105	COG4735	regulation of single-species biofilm formation
HBJ12_RS22110	COG1584	GPR1 FUN34 yaaH family protein
HBJ12_RS22115	COG0477	Major facilitator Superfamily
HBJ12_RS22120	COG0521	Mo-molybdopterin cofactor biosynthetic process
HBJ12_RS22125	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HBJ12_RS22130	COG1115	amino acid carrier protein
HBJ12_RS22145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HBJ12_RS22155	COG0460	homoserine dehydrogenase
HBJ12_RS22155	COG0527	aspartate kinase activity
HBJ12_RS22165	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HBJ12_RS22175	COG0745	RESPONSE REGULATOR receiver
HBJ12_RS22180	COG4452	Inner membrane protein CreD
HBJ12_RS22185	COG2205	protein histidine kinase activity
HBJ12_RS22190	COG0745	RESPONSE REGULATOR receiver
HBJ12_RS22195	COG3045	CreA protein
HBJ12_RS22200	COG2207	Transcriptional regulator
HBJ12_RS22200	COG3708	Transcriptional regulator
HBJ12_RS22220	COG0741	lytic transglycosylase activity
HBJ12_RS22225	COG0488	(ABC) transporter
HBJ12_RS22235	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HBJ12_RS22240	COG0560	Phosphoserine phosphatase
HBJ12_RS22245	COG3726	membrane protein affecting hemolysin expression
HBJ12_RS22275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBJ12_RS22280	COG0084	hydrolase, TatD family'
HBJ12_RS22285	COG4667	esterase of the alpha-beta hydrolase superfamily
HBJ12_RS22295	COG2823	Periplasmic or secreted lipoprotein
HBJ12_RS22305	COG1011	Hydrolase
HBJ12_RS22310	COG0456	acetyltransferase
HBJ12_RS22315	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HBJ12_RS22350	COG3706	GGDEF domain
HBJ12_RS22355	COG4114	ferric iron reductase
HBJ12_RS22360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS22360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS22365	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBJ12_RS22370	COG2197	response regulator
HBJ12_RS22375	COG2197	response regulator
HBJ12_RS22390	COG2966	Psort location CytoplasmicMembrane, score
HBJ12_RS22405	COG1484	DNA-dependent DNA replication
HBJ12_RS22420	COG5464	transposase or invertase
HBJ12_RS22430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HBJ12_RS22435	COG3716	PTS system mannose fructose sorbose family IID component
HBJ12_RS22440	COG3715	PTS system
HBJ12_RS22455	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HBJ12_RS22455	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HBJ12_RS22465	COG1063	alcohol dehydrogenase
HBJ12_RS22470	COG1802	Transcriptional regulator
HBJ12_RS22475	COG2271	Major facilitator Superfamily
HBJ12_RS22480	COG1214	PFAM Peptidase M22, glycoprotease
HBJ12_RS22480	COG0456	acetyltransferase
HBJ12_RS22490	COG1737	Transcriptional regulator
HBJ12_RS22495	COG0800	Aldolase
HBJ12_RS22500	COG3734	2-keto-3-deoxy-galactonokinase
HBJ12_RS22515	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HBJ12_RS22545	COG1846	Transcriptional regulator
HBJ12_RS22555	COG0179	Fumarylacetoacetate (FAA) hydrolase
HBJ12_RS22565	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS22570	COG3384	dioxygenase
HBJ12_RS22580	COG3971	2-oxopent-4-enoate hydratase activity
HBJ12_RS22600	COG2368	4-hydroxyphenylacetate
HBJ12_RS22605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBJ12_RS22620	COG1966	Carbon starvation protein
HBJ12_RS22625	COG2879	small protein
HBJ12_RS22630	COG0523	cobalamin synthesis protein
HBJ12_RS22640	COG1012	belongs to the aldehyde dehydrogenase family
HBJ12_RS22645	COG5464	transposase or invertase
HBJ12_RS22650	COG1917	Cupin 2, conserved barrel domain protein
HBJ12_RS22650	COG2207	Transcriptional regulator
HBJ12_RS22660	COG2733	membrane
HBJ12_RS22675	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HBJ12_RS22680	COG1924	4 iron, 4 sulfur cluster binding
HBJ12_RS22695	COG1566	PFAM secretion protein HlyD family protein
HBJ12_RS22705	COG5457	Domain of unknown function (DUF1127)
HBJ12_RS22710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBJ12_RS22720	COG0583	DNA-binding transcription factor activity
HBJ12_RS22725	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBJ12_RS22735	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS22740	COG1129	ABC transporter
HBJ12_RS22745	COG1879	ABC-type sugar transport system periplasmic component
HBJ12_RS22755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBJ12_RS22760	COG0842	Transport permease protein
HBJ12_RS22760	COG1129	ABC transporter
HBJ12_RS22765	COG0842	Transport permease protein
HBJ12_RS22825	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBJ12_RS22895	COG3272	Protein of unknown function (DUF1722)
HBJ12_RS22915	COG2211	Major facilitator Superfamily
HBJ12_RS22920	COG3507	Belongs to the glycosyl hydrolase 43 family
HBJ12_RS23025	COG0582	viral genome integration into host DNA
HBJ12_RS23035	COG0288	reversible hydration of carbon dioxide
HBJ12_RS23040	COG0659	secondary active sulfate transmembrane transporter activity
HBJ12_RS23045	COG1064	alcohol dehydrogenase
HBJ12_RS23050	COG1175	transmembrane transport
HBJ12_RS23055	COG0395	ABC-type sugar transport system, permease component
HBJ12_RS23060	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HBJ12_RS23065	COG3842	ATPase activity
HBJ12_RS23070	COG1653	transport
HBJ12_RS23080	COG1082	Xylose isomerase domain protein TIM barrel
HBJ12_RS23090	COG3962	Belongs to the TPP enzyme family
HBJ12_RS23095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBJ12_RS23100	COG1737	Transcriptional regulator
HBJ12_RS23100	COG0837	glucose binding
HBJ12_RS23105	COG3718	enzyme involved in inositol metabolism
HBJ12_RS23120	COG0433	COG0433 Predicted ATPase
HBJ12_RS23125	COG0795	lipopolysaccharide-transporting ATPase activity
HBJ12_RS23130	COG0795	lipopolysaccharide-transporting ATPase activity
HBJ12_RS23140	COG2927	DNA polymerase III (CHI subunit)
HBJ12_RS23145	COG0525	valine-tRNA ligase activity
HBJ12_RS23170	COG2188	Transcriptional regulator
HBJ12_RS23175	COG1288	antiporter activity
HBJ12_RS23180	COG1228	amidohydrolase
HBJ12_RS23185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBJ12_RS23190	COG2222	sugar isomerase
HBJ12_RS23195	COG2731	YhcH YjgK YiaL family protein
HBJ12_RS23230	COG1263	PTS System
HBJ12_RS23230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBJ12_RS23235	COG0366	Alpha amylase catalytic
HBJ12_RS23240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBJ12_RS23245	COG1486	melibiose metabolic process
HBJ12_RS23270	COG0602	queuosine metabolic process
HBJ12_RS23275	COG2026	Addiction module toxin, RelE StbE family
HBJ12_RS23280	COG3077	Addiction module antitoxin, RelB DinJ family
HBJ12_RS23285	COG3711	transcriptional antiterminator
HBJ12_RS23285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBJ12_RS23290	COG2706	6-phosphogluconolactonase activity
HBJ12_RS23305	COG3964	amidohydrolase
HBJ12_RS23345	COG0312	modulator of DNA gyrase
HBJ12_RS23370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HBJ12_RS23380	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS23385	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS23390	COG1129	ABC transporter
HBJ12_RS23395	COG1879	ABC-type sugar transport system periplasmic component
HBJ12_RS23415	COG2105	PFAM AIG2 family protein
HBJ12_RS23420	COG2911	Protein conserved in bacteria
HBJ12_RS23425	COG0729	surface antigen
HBJ12_RS23435	COG1253	flavin adenine dinucleotide binding
HBJ12_RS23450	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HBJ12_RS23465	COG1733	regulation of RNA biosynthetic process
HBJ12_RS23470	COG0702	epimerase
HBJ12_RS23480	COG0697	spore germination
HBJ12_RS23490	COG1113	amino acid transport
HBJ12_RS23495	COG0545	Peptidyl-prolyl cis-trans isomerase
HBJ12_RS23500	COG3061	Opacity-associated protein A
HBJ12_RS23510	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HBJ12_RS23515	COG2965	DNA replication, synthesis of RNA primer
HBJ12_RS23575	COG1073	alpha beta
HBJ12_RS23580	COG3650	response to hydrogen peroxide
HBJ12_RS23590	COG1960	acyl-CoA dehydrogenase activity
HBJ12_RS23595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBJ12_RS23600	COG0557	exoribonuclease II activity
HBJ12_RS23615	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HBJ12_RS23625	COG0330	HflC and HflK could
HBJ12_RS23630	COG0330	HflC and HflK could
HBJ12_RS23635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBJ12_RS23655	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBJ12_RS23660	COG0802	atpase or kinase
HBJ12_RS23665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HBJ12_RS23665	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HBJ12_RS23670	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HBJ12_RS23690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBJ12_RS23710	COG3264	Mechanosensitive ion channel
HBJ12_RS23710	COG1511	domain protein
HBJ12_RS23725	COG1053	succinate dehydrogenase
HBJ12_RS23730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HBJ12_RS23750	COG2076	Multidrug Resistance protein
HBJ12_RS23755	COG5510	response to toxic substance
HBJ12_RS23770	COG1509	lysine 2,3-aminomutase activity
HBJ12_RS23840	COG0531	amino acid
HBJ12_RS23845	COG3030	protein affecting phage T7 exclusion by the F plasmid
HBJ12_RS23850	COG1027	Aspartate ammonia-lyase
HBJ12_RS23855	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HBJ12_RS23870	COG1309	transcriptional regulator
HBJ12_RS23900	COG0457	Tetratricopeptide repeat
HBJ12_RS23905	COG1649	PFAM Uncharacterised BCR, COG1649
HBJ12_RS23905	COG0726	polysaccharide deacetylase
HBJ12_RS23910	COG1215	transferase activity, transferring glycosyl groups
HBJ12_RS23925	COG0861	Integral membrane protein TerC family
HBJ12_RS23970	COG1486	melibiose metabolic process
HBJ12_RS23975	COG2169	Transcriptional regulator
HBJ12_RS23985	COG2824	Alkylphosphonate utilization operon protein PhnA
HBJ12_RS23990	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HBJ12_RS23995	COG2188	Transcriptional regulator
HBJ12_RS24000	COG3624	Phosphonate C-P lyase system protein PhnG
HBJ12_RS24005	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HBJ12_RS24010	COG3626	phosphonate metabolism
HBJ12_RS24020	COG4107	phosphonate C-P lyase system protein PhnK
HBJ12_RS24025	COG4778	phosphonate C-P lyase system protein PhnL
HBJ12_RS24030	COG3454	Phosphonate metabolism
HBJ12_RS24040	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HBJ12_RS24050	COG0784	Response regulator, receiver
HBJ12_RS24050	COG4191	Histidine kinase
HBJ12_RS24055	COG1129	ABC transporter
HBJ12_RS24060	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS24095	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HBJ12_RS24100	COG1301	dicarboxylic acid transport
HBJ12_RS24110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBJ12_RS24115	COG3162	membrane
HBJ12_RS24145	COG3539	Fimbrial protein
HBJ12_RS24150	COG1346	cytolysis
HBJ12_RS24155	COG1380	Effector of murein hydrolase LrgA
HBJ12_RS24160	COG0583	DNA-binding transcription factor activity
HBJ12_RS24165	COG0025	NhaP-type Na H and K H
HBJ12_RS24170	COG2252	PERMEase
HBJ12_RS24175	COG0625	glutathione transferase activity
HBJ12_RS24180	COG0789	Transcriptional regulator
HBJ12_RS24190	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HBJ12_RS24220	COG1234	tRNA 3'-trailer cleavage
HBJ12_RS24225	COG1609	Transcriptional regulator
HBJ12_RS24230	COG0483	inositol monophosphate 1-phosphatase activity
HBJ12_RS24240	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HBJ12_RS24260	COG4771	TonB-dependent receptor
HBJ12_RS24265	COG0741	lytic transglycosylase activity
HBJ12_RS24280	COG2315	Protein conserved in bacteria
HBJ12_RS24285	COG0432	Pfam Uncharacterised protein family UPF0047
HBJ12_RS24300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBJ12_RS24305	COG0305	Participates in initiation and elongation during chromosome replication
HBJ12_RS24320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBJ12_RS24330	COG0735	belongs to the Fur family
HBJ12_RS24335	COG3237	CsbD-like
HBJ12_RS24345	COG0534	Mate efflux family protein
HBJ12_RS24355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HBJ12_RS24425	COG0251	oxidation-reduction process
HBJ12_RS24435	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HBJ12_RS24445	COG0527	aspartate kinase activity
HBJ12_RS24500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HBJ12_RS24530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HBJ12_RS24540	COG0456	acetyltransferase
HBJ12_RS24570	COG0151	Belongs to the GarS family
HBJ12_RS24580	COG4191	Histidine kinase
HBJ12_RS24585	COG3678	ATP-independent chaperone mediated protein folding
HBJ12_RS24620	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HBJ12_RS24635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HBJ12_RS24640	COG2104	thiamine diphosphate biosynthetic process
HBJ12_RS24655	COG3706	GGDEF domain
HBJ12_RS24665	COG1447	Phosphotransferase system cellobiose-specific component IIA
HBJ12_RS24670	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HBJ12_RS24705	COG0250	Participates in transcription elongation, termination and antitermination
HBJ12_RS24750	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HBJ12_RS24780	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HBJ12_RS24790	COG1739	Uncharacterized protein family UPF0029
HBJ12_RS24830	COG0805	protein transport
HBJ12_RS24850	COG3165	ubiquinone biosynthetic process from chorismate
HBJ12_RS24880	COG0583	DNA-binding transcription factor activity
HBJ12_RS24885	COG0697	spore germination
HBJ12_RS24890	COG0561	phosphatase activity
HBJ12_RS24895	COG2267	carboxylic ester hydrolase activity
HBJ12_RS24900	COG1280	lysine exporter protein (LysE YggA)
HBJ12_RS24910	COG1280	lysine exporter protein (LysE YggA)
HBJ12_RS24940	COG0210	DNA helicase
HBJ12_RS24945	COG1011	Hydrolase
HBJ12_RS24975	COG3072	Adenylate cyclase
HBJ12_RS24990	COG2959	enzyme of heme biosynthesis
HBJ12_RS24995	COG3071	HemY protein
HBJ12_RS25040	COG2244	polysaccharide biosynthetic process
HBJ12_RS25045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HBJ12_RS25050	COG0456	acetyltransferase
HBJ12_RS25055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HBJ12_RS25060	COG1088	dTDP-glucose 4,6-dehydratase activity
HBJ12_RS25065	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HBJ12_RS25070	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HBJ12_RS25080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HBJ12_RS25085	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HBJ12_RS25090	COG3118	belongs to the thioredoxin family
HBJ12_RS25115	COG1811	Na channel or pump
HBJ12_RS25125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBJ12_RS25130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBJ12_RS25140	COG0583	DNA-binding transcription factor activity
HBJ12_RS25145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBJ12_RS25160	COG3978	acetolactate synthase activity
HBJ12_RS25180	COG3085	chromosome segregation
HBJ12_RS25255	COG0583	DNA-binding transcription factor activity
HBJ12_RS25270	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HBJ12_RS25285	COG3443	Belongs to the bacterial solute-binding protein 9 family
HBJ12_RS25290	COG2207	Transcriptional regulator
HBJ12_RS25300	COG0371	Dehydrogenase
HBJ12_RS25305	COG0697	spore germination
HBJ12_RS25315	COG0583	DNA-binding transcription factor activity
HBJ12_RS25325	COG0737	Belongs to the 5'-nucleotidase family
HBJ12_RS25335	COG0527	aspartate kinase activity
HBJ12_RS25335	COG0460	homoserine dehydrogenase
HBJ12_RS25340	COG0626	cystathionine gamma-synthase activity
HBJ12_RS25355	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBJ12_RS25360	COG1609	Transcriptional regulator
HBJ12_RS25365	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HBJ12_RS25380	COG1575	Belongs to the MenA family. Type 1 subfamily
HBJ12_RS25400	COG3678	ATP-independent chaperone mediated protein folding
HBJ12_RS25405	COG0745	RESPONSE REGULATOR receiver
HBJ12_RS25410	COG2205	protein histidine kinase activity
HBJ12_RS25415	COG2258	MOSC domain
HBJ12_RS25420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HBJ12_RS25460	COG1129	ABC transporter
HBJ12_RS25465	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS25470	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS25475	COG1454	alcohol dehydrogenase
HBJ12_RS25485	COG2211	Major facilitator Superfamily
HBJ12_RS25545	COG0205	6-phosphofructokinase activity
HBJ12_RS25565	COG0437	4 iron, 4 sulfur cluster binding
HBJ12_RS25570	COG2864	formate dehydrogenase
HBJ12_RS25585	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HBJ12_RS25590	COG0657	acetylesterase activity
HBJ12_RS25595	COG0456	acetyltransferase
HBJ12_RS25610	COG1011	Hydrolase
HBJ12_RS25625	COG3852	Histidine kinase
HBJ12_RS25640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HBJ12_RS25660	COG0204	Acyl-transferase
HBJ12_RS25670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HBJ12_RS25675	COG3084	Protein conserved in bacteria
HBJ12_RS25685	COG1763	Mo-molybdopterin cofactor biosynthetic process
HBJ12_RS25710	COG2186	Transcriptional regulator
HBJ12_RS25715	COG0477	Major facilitator Superfamily
HBJ12_RS25720	COG1609	Transcriptional regulator
HBJ12_RS25725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBJ12_RS25735	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBJ12_RS25740	COG1129	ABC transporter
HBJ12_RS25770	COG1522	sequence-specific DNA binding
HBJ12_RS25775	COG0716	FMN binding
HBJ12_RS25790	COG3312	ion transport
HBJ12_RS25840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HBJ12_RS25845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HBJ12_RS25850	COG0573	inorganic phosphate transmembrane transporter activity
HBJ12_RS25855	COG0581	inorganic phosphate transmembrane transporter activity
HBJ12_RS25860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HBJ12_RS25865	COG0704	Plays a role in the regulation of phosphate uptake
HBJ12_RS25875	COG2382	esterase
HBJ12_RS25880	COG0363	glucosamine-6-phosphate deaminase activity
HBJ12_RS25885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HBJ12_RS25890	COG2252	PERMEase
HBJ12_RS25895	COG0431	NADPH-dependent FMN reductase
HBJ12_RS25900	COG2091	lysine biosynthetic process via aminoadipic acid
HBJ12_RS25930	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HBJ12_RS26000	COG0459	protein refolding
HBJ12_RS26050	COG0673	inositol 2-dehydrogenase activity
HBJ12_RS26120	COG3173	Aminoglycoside phosphotransferase
HBJ12_RS26150	COG1196	nuclear chromosome segregation
HBJ12_RS26215	COG3344	reverse transcriptase
HBJ12_RS26530	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity