locus-tag	class	description
IC568_RS00020	COG0187	DNA topoisomerase II activity
IC568_RS00025	COG0561	phosphatase activity
IC568_RS00040	COG2186	Transcriptional regulator
IC568_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
IC568_RS00050	COG0800	Aldolase
IC568_RS00060	COG2271	Major facilitator Superfamily
IC568_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
IC568_RS00070	COG5645	(Lipo)protein
IC568_RS00095	COG2188	Transcriptional regulator
IC568_RS00110	COG2149	membrane
IC568_RS00130	COG2610	gluconate transmembrane transporter activity
IC568_RS00140	COG0583	DNA-binding transcription factor activity
IC568_RS00145	COG2814	Major facilitator Superfamily
IC568_RS00175	COG0028	Belongs to the TPP enzyme family
IC568_RS00180	COG0440	acetolactate synthase activity
IC568_RS00185	COG2197	response regulator
IC568_RS00195	COG2271	Major facilitator Superfamily
IC568_RS00235	COG2188	Transcriptional regulator
IC568_RS00260	COG4580	involved in the transport of maltose and maltodextrins
IC568_RS00265	COG1447	Phosphotransferase system cellobiose-specific component IIA
IC568_RS00270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC568_RS00270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC568_RS00280	COG1609	Transcriptional regulator
IC568_RS00290	COG3384	dioxygenase
IC568_RS00295	COG0583	DNA-binding transcription factor activity
IC568_RS00300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IC568_RS00305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC568_RS00310	COG2828	Protein conserved in bacteria
IC568_RS00325	COG0697	spore germination
IC568_RS00330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC568_RS00330	COG1263	PTS System
IC568_RS00340	COG2814	Major facilitator Superfamily
IC568_RS00350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC568_RS00385	COG0583	DNA-binding transcription factor activity
IC568_RS00410	COG1464	Belongs to the NlpA lipoprotein family
IC568_RS00425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IC568_RS00435	COG1064	alcohol dehydrogenase
IC568_RS00465	COG2211	Major facilitator Superfamily
IC568_RS00470	COG1501	Belongs to the glycosyl hydrolase 31 family
IC568_RS00480	COG1486	melibiose metabolic process
IC568_RS00485	COG1263	PTS System
IC568_RS00485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC568_RS00490	COG2982	Protein involved in outer membrane biogenesis
IC568_RS00495	COG2233	PERMEase
IC568_RS00500	COG0786	glutamate:sodium symporter activity
IC568_RS00520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC568_RS00545	COG3152	Membrane
IC568_RS00555	COG1494	fructose-1,6-bisphosphatase
IC568_RS00560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC568_RS00565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC568_RS00570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC568_RS00590	COG2860	membrane
IC568_RS00600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC568_RS00600	COG2169	Transcriptional regulator
IC568_RS00605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IC568_RS00610	COG1561	YicC-like family, N-terminal region
IC568_RS00630	COG1131	(ABC) transporter
IC568_RS00635	COG0842	Transport permease protein
IC568_RS00660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC568_RS00695	COG1519	Transferase
IC568_RS00700	COG1216	Glycosyl transferase, family 2
IC568_RS00705	COG0438	transferase activity, transferring glycosyl groups
IC568_RS00715	COG0859	PFAM glycosyl transferase family 9
IC568_RS00725	COG1216	Glycosyl transferase, family 2
IC568_RS00725	COG1442	glycosyl transferase family 8
IC568_RS00730	COG3307	-O-antigen
IC568_RS00735	COG0438	transferase activity, transferring glycosyl groups
IC568_RS00740	COG0859	PFAM glycosyl transferase family 9
IC568_RS00755	COG0156	8-amino-7-oxononanoate synthase activity
IC568_RS00765	COG0463	Glycosyl transferase, family 2
IC568_RS00770	COG2861	carbohydrate metabolic process
IC568_RS00775	COG4942	peptidase
IC568_RS00785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IC568_RS00790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC568_RS00810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC568_RS00820	COG2186	Transcriptional regulator
IC568_RS00840	COG3722	fumarate hydratase activity
IC568_RS00860	COG1566	PFAM secretion protein HlyD family protein
IC568_RS00865	COG0625	glutathione transferase activity
IC568_RS00875	COG3276	selenocysteine insertion sequence binding
IC568_RS00880	COG1414	Transcriptional regulator
IC568_RS00885	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC568_RS00890	COG3977	Valine--pyruvate aminotransferase
IC568_RS00895	COG0366	Alpha amylase catalytic
IC568_RS00900	COG2992	FlgJ-related protein
IC568_RS00905	COG1609	Transcriptional regulator
IC568_RS00905	COG2207	Transcriptional regulator
IC568_RS00910	COG4214	carbohydrate transport
IC568_RS00920	COG4213	ABC transporter substrate-binding protein
IC568_RS00935	COG4682	membrane
IC568_RS00940	COG4682	membrane
IC568_RS00945	COG3274	enterobacterial common antigen metabolic process
IC568_RS00995	COG1278	Cold shock
IC568_RS01000	COG2944	sequence-specific DNA binding
IC568_RS01005	COG2814	Major facilitator Superfamily
IC568_RS01025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC568_RS01035	COG1609	Transcriptional regulator
IC568_RS01040	COG2885	chlorophyll binding
IC568_RS01045	COG0243	molybdopterin cofactor binding
IC568_RS01050	COG0456	acetyltransferase
IC568_RS01055	COG2818	Glycosylase
IC568_RS01060	COG5571	outer membrane autotransporter
IC568_RS01065	COG2223	nitrite transmembrane transporter activity
IC568_RS01090	COG0747	negative chemotaxis
IC568_RS01095	COG0601	transmembrane transport
IC568_RS01100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC568_RS01105	COG0444	Belongs to the ABC transporter superfamily
IC568_RS01110	COG4608	Belongs to the ABC transporter superfamily
IC568_RS01125	COG2894	cell division
IC568_RS01135	COG1215	transferase activity, transferring glycosyl groups
IC568_RS01140	COG0457	Tetratricopeptide repeat
IC568_RS01155	COG2194	sulfuric ester hydrolase activity
IC568_RS01185	COG1215	transferase activity, transferring glycosyl groups
IC568_RS01190	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IC568_RS01195	COG0457	Tetratricopeptide repeat
IC568_RS01195	COG3118	belongs to the thioredoxin family
IC568_RS01200	COG2200	EAL domain
IC568_RS01200	COG2199	diguanylate cyclase activity
IC568_RS01210	COG0612	Peptidase, M16
IC568_RS01220	COG2982	Protein involved in outer membrane biogenesis
IC568_RS01225	COG0477	Major facilitator Superfamily
IC568_RS01230	COG1295	ribonuclease BN
IC568_RS01235	COG0583	DNA-binding transcription factor activity
IC568_RS01240	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS01245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC568_RS01255	COG1454	alcohol dehydrogenase
IC568_RS01265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC568_RS01270	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC568_RS01275	COG0671	phosphoesterase, PA-phosphatase related
IC568_RS01295	COG0589	response to stress
IC568_RS01305	COG0306	phosphate transporter
IC568_RS01310	COG2081	HI0933 family
IC568_RS01315	COG2239	Acts as a magnesium transporter
IC568_RS01330	COG1124	(ABC) transporter
IC568_RS01340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC568_RS01345	COG0601	transmembrane transport
IC568_RS01350	COG0747	negative chemotaxis
IC568_RS01360	COG3479	Phenolic acid decarboxylase
IC568_RS01400	COG0628	permease
IC568_RS01405	COG0477	Major facilitator Superfamily
IC568_RS01415	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IC568_RS01430	COG3714	YhhN family
IC568_RS01440	COG3776	membrane
IC568_RS01445	COG0742	ribosomal rna small subunit methyltransferase
IC568_RS01450	COG0552	protein localization to endoplasmic reticulum
IC568_RS01455	COG2884	Cell division ATP-binding protein ftsE
IC568_RS01460	COG2177	Part of the ABC transporter FtsEX involved in
IC568_RS01475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC568_RS01485	COG0683	leucine binding
IC568_RS01495	COG0683	leucine binding
IC568_RS01500	COG0559	Belongs to the binding-protein-dependent transport system permease family
IC568_RS01550	COG0584	glycerophosphoryl diester phosphodiesterase
IC568_RS01560	COG0405	Gamma-glutamyltransferase
IC568_RS01565	COG1247	-acetyltransferase
IC568_RS01575	COG0673	inositol 2-dehydrogenase activity
IC568_RS01580	COG1741	Belongs to the pirin family
IC568_RS01585	COG1609	Transcriptional regulator
IC568_RS01590	COG3265	gluconokinase activity
IC568_RS01595	COG2610	gluconate transmembrane transporter activity
IC568_RS01605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IC568_RS01630	COG0058	SHG alpha-glucan phosphorylase activity
IC568_RS01635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IC568_RS01650	COG1349	DNA-binding transcription factor activity
IC568_RS01660	COG0058	SHG alpha-glucan phosphorylase activity
IC568_RS01665	COG1640	4-alpha-glucanotransferase
IC568_RS01670	COG2610	gluconate transmembrane transporter activity
IC568_RS01680	COG1040	competence protein
IC568_RS01705	COG1918	ferrous iron import across plasma membrane
IC568_RS01710	COG2183	response to ionizing radiation
IC568_RS01715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC568_RS01740	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC568_RS01745	COG1011	Hydrolase
IC568_RS01755	COG0494	nUDIX hydrolase
IC568_RS01760	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IC568_RS01785	COG4796	Type ii and iii secretion system protein
IC568_RS01800	COG3266	domain, Protein
IC568_RS01805	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IC568_RS01810	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC568_RS01835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC568_RS01840	COG0402	S-adenosylhomocysteine deaminase activity
IC568_RS01845	COG0738	Major facilitator superfamily
IC568_RS01870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC568_RS01875	COG1289	transmembrane transporter activity
IC568_RS01885	COG1765	OsmC-like protein
IC568_RS01890	COG3954	Phosphoribulokinase
IC568_RS01900	COG0429	hydrolase of the alpha beta-hydrolase fold
IC568_RS01905	COG0488	(ABC) transporter
IC568_RS01920	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC568_RS01925	COG1047	Peptidyl-prolyl cis-trans
IC568_RS01935	COG0545	Peptidyl-prolyl cis-trans isomerase
IC568_RS01940	COG2964	Protein conserved in bacteria
IC568_RS01995	COG0051	transcription antitermination factor activity, RNA binding
IC568_RS02020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IC568_RS02035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IC568_RS02100	COG0201	protein transport
IC568_RS02125	COG0202	RNA polymerase activity
IC568_RS02140	COG0789	Transcriptional regulator
IC568_RS02145	COG3036	rescue of stalled ribosome
IC568_RS02175	COG0758	DNA mediated transformation
IC568_RS02185	COG0551	DNA topoisomerase type I activity
IC568_RS02205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC568_RS02240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC568_RS02245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC568_RS02250	COG1309	transcriptional regulator
IC568_RS02270	COG4145	pantothenate transmembrane transporter activity
IC568_RS02275	COG3924	membrane
IC568_RS02280	COG0439	Biotin carboxylase
IC568_RS02285	COG0511	ligase activity, forming carbon-carbon bonds
IC568_RS02310	COG2200	EAL domain
IC568_RS02310	COG2199	diguanylate cyclase activity
IC568_RS02315	COG1077	Cell shape determining protein MreB Mrl
IC568_RS02320	COG1792	Involved in formation and maintenance of cell shape
IC568_RS02325	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC568_RS02335	COG1530	ribonuclease E activity
IC568_RS02340	COG3164	Protein of unknown function
IC568_RS02345	COG0312	modulator of DNA gyrase
IC568_RS02350	COG0583	DNA-binding transcription factor activity
IC568_RS02365	COG1289	transmembrane transporter activity
IC568_RS02370	COG2732	(Barnase) inhibitor
IC568_RS02395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC568_RS02400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC568_RS02405	COG3105	Protein conserved in bacteria
IC568_RS02410	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC568_RS02430	COG0625	glutathione transferase activity
IC568_RS02435	COG2969	positive regulation of protein catabolic process
IC568_RS02445	COG0493	'glutamate synthase
IC568_RS02450	COG0067	glutamate synthase
IC568_RS02450	COG0069	glutamate synthase activity
IC568_RS02450	COG0070	glutamate synthase
IC568_RS02455	COG1242	4 iron, 4 sulfur cluster binding
IC568_RS02460	COG2271	Major facilitator Superfamily
IC568_RS02465	COG1063	alcohol dehydrogenase
IC568_RS02470	COG1312	Catalyzes the dehydration of D-mannonate
IC568_RS02475	COG5002	protein histidine kinase activity
IC568_RS02475	COG0784	Response regulator, receiver
IC568_RS02475	COG2198	Histidine kinase
IC568_RS02480	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IC568_RS02485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC568_RS02490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS02500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS02505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IC568_RS02510	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IC568_RS02515	COG1137	ATPase activity
IC568_RS02520	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC568_RS02525	COG3117	lipopolysaccharide transmembrane transporter activity
IC568_RS02530	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC568_RS02540	COG0530	calcium, potassium:sodium antiporter activity
IC568_RS02545	COG1127	ABC transporter
IC568_RS02550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC568_RS02555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC568_RS02560	COG2854	intermembrane phospholipid transfer
IC568_RS02565	COG3113	response to antibiotic
IC568_RS02570	COG5007	Belongs to the BolA IbaG family
IC568_RS02580	COG3423	Transcriptional regulator
IC568_RS02585	COG0142	geranyltranstransferase activity
IC568_RS02600	COG0697	spore germination
IC568_RS02610	COG2027	D-alanyl-D-alanine carboxypeptidase
IC568_RS02620	COG1534	Rna-binding protein
IC568_RS02630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC568_RS02635	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IC568_RS02645	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IC568_RS02685	COG0195	Participates in both transcription termination and antitermination
IC568_RS02730	COG0814	amino acid
IC568_RS02735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC568_RS02740	COG0826	peptidase U32
IC568_RS02745	COG0826	peptidase U32
IC568_RS02750	COG3154	lipid carrier protein
IC568_RS02755	COG3153	acetyltransferase
IC568_RS02770	COG0693	protein deglycase activity
IC568_RS02775	COG0702	epimerase
IC568_RS02780	COG0701	Predicted permease
IC568_RS02785	COG2823	Periplasmic or secreted lipoprotein
IC568_RS02805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IC568_RS02820	COG1063	alcohol dehydrogenase
IC568_RS02825	COG3775	system Galactitol-specific IIC component
IC568_RS02830	COG3414	Phosphotransferase system galactitol-specific IIB component
IC568_RS02835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS02845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS02845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS02850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS02850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC568_RS02850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC568_RS02855	COG1105	Belongs to the carbohydrate kinase PfkB family
IC568_RS02865	COG1349	DNA-binding transcription factor activity
IC568_RS02870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC568_RS02875	COG2721	sulfolactate sulfo-lyase activity
IC568_RS02880	COG2271	Major facilitator Superfamily
IC568_RS02890	COG2084	Dehydrogenase
IC568_RS02895	COG1929	Belongs to the glycerate kinase type-1 family
IC568_RS02920	COG1741	Belongs to the pirin family
IC568_RS02925	COG0583	DNA-binding transcription factor activity
IC568_RS02930	COG3152	Membrane
IC568_RS02935	COG0435	Glutathione S-transferase
IC568_RS02940	COG2259	Doxx family
IC568_RS02950	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
IC568_RS02955	COG4575	ribosome binding
IC568_RS02960	COG1422	Protein of unknown function (DUF1090)
IC568_RS02970	COG0586	Pfam SNARE associated Golgi protein
IC568_RS02975	COG2186	Transcriptional regulator
IC568_RS02980	COG2271	Major facilitator Superfamily
IC568_RS02990	COG2721	sulfolactate sulfo-lyase activity
IC568_RS03005	COG0861	Integral membrane protein TerC family
IC568_RS03010	COG0673	inositol 2-dehydrogenase activity
IC568_RS03015	COG1451	nucleotide metabolic process
IC568_RS03035	COG1902	pentaerythritol trinitrate reductase activity
IC568_RS03035	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC568_RS03085	COG1695	Transcriptional regulator
IC568_RS03090	COG2375	cellular response to nickel ion
IC568_RS03105	COG1461	Dihydroxyacetone kinase
IC568_RS03110	COG2376	Dihydroxyacetone kinase
IC568_RS03180	COG3247	response to pH
IC568_RS03190	COG2198	Histidine kinase
IC568_RS03190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC568_RS03190	COG0784	Response regulator, receiver
IC568_RS03190	COG2205	protein histidine kinase activity
IC568_RS03195	COG2197	response regulator
IC568_RS03220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IC568_RS03225	COG0358	DNA primase activity
IC568_RS03230	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IC568_RS03295	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IC568_RS03310	COG4991	sh3 domain protein
IC568_RS03315	COG3025	triphosphatase activity
IC568_RS03340	COG2960	long-chain fatty acid transporting porin activity
IC568_RS03355	COG3384	dioxygenase
IC568_RS03360	COG0754	glutathionylspermidine amidase activity
IC568_RS03375	COG0494	nUDIX hydrolase
IC568_RS03380	COG3151	Protein conserved in bacteria
IC568_RS03385	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IC568_RS03390	COG3150	esterase
IC568_RS03400	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC568_RS03405	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC568_RS03410	COG0642	Histidine kinase
IC568_RS03420	COG3111	PFAM Bacterial OB fold (BOF) protein
IC568_RS03425	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC568_RS03430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IC568_RS03435	COG0204	Acyl-transferase
IC568_RS03440	COG2132	Multicopper oxidase
IC568_RS03445	COG1032	radical SAM domain protein
IC568_RS03455	COG0656	L-ascorbic acid biosynthetic process
IC568_RS03460	COG1979	alcohol dehydrogenase
IC568_RS03465	COG2207	Transcriptional regulator
IC568_RS03470	COG0586	Pfam SNARE associated Golgi protein
IC568_RS03475	COG0626	cystathionine gamma-synthase activity
IC568_RS03490	COG0848	biopolymer transport protein
IC568_RS03510	COG0625	glutathione transferase activity
IC568_RS03525	COG0754	glutathionylspermidine amidase activity
IC568_RS03530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC568_RS03550	COG0583	DNA-binding transcription factor activity
IC568_RS03555	COG0626	cystathionine gamma-synthase activity
IC568_RS03570	COG3121	Chaperone
IC568_RS03585	COG3121	Chaperone
IC568_RS03590	COG3121	Chaperone
IC568_RS03595	COG3188	usher protein
IC568_RS03620	COG1811	Na channel or pump
IC568_RS03625	COG1982	Orn Lys Arg decarboxylase major
IC568_RS03630	COG2211	Major facilitator Superfamily
IC568_RS03645	COG1194	a g-specific adenine glycosylase
IC568_RS03655	COG3171	Protein conserved in bacteria
IC568_RS03665	COG4214	carbohydrate transport
IC568_RS03680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC568_RS03695	COG0762	integral membrane protein
IC568_RS03700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IC568_RS03705	COG2805	Type II/IV secretion system protein
IC568_RS03725	COG0189	ligase activity
IC568_RS03730	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC568_RS03735	COG2356	endonuclease I
IC568_RS03745	COG2814	Major facilitator Superfamily
IC568_RS03780	COG2146	nitrite reductase [NAD(P)H] activity
IC568_RS03795	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS03800	COG1414	Transcriptional regulator
IC568_RS03830	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS03835	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
IC568_RS03855	COG0501	Belongs to the peptidase M48B family
IC568_RS03860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC568_RS03875	COG0191	fructose-bisphosphate aldolase activity
IC568_RS03880	COG0668	transmembrane transport
IC568_RS03890	COG2968	Membrane
IC568_RS03905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC568_RS03910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC568_RS03930	COG0006	proline dipeptidase activity
IC568_RS03935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC568_RS03940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC568_RS03960	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS03970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IC568_RS03990	COG2723	6-phospho-beta-galactosidase activity
IC568_RS03995	COG1737	Transcriptional regulator
IC568_RS04005	COG1272	protein, Hemolysin III
IC568_RS04015	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC568_RS04025	COG0716	FMN binding
IC568_RS04030	COG4974	Belongs to the 'phage' integrase family
IC568_RS04040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IC568_RS04060	COG4942	peptidase
IC568_RS04070	COG2814	Major facilitator Superfamily
IC568_RS04085	COG0667	Aldo Keto reductase
IC568_RS04125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IC568_RS04130	COG1393	Belongs to the ArsC family
IC568_RS04145	COG1538	Outer membrane efflux protein
IC568_RS04150	COG1289	transmembrane transporter activity
IC568_RS04165	COG3592	Divergent 4Fe-4S mono-cluster
IC568_RS04170	COG2388	GCN5-related N-acetyl-transferase
IC568_RS04180	COG3539	Fimbrial protein
IC568_RS04185	COG3539	Fimbrial protein
IC568_RS04190	COG3539	Fimbrial protein
IC568_RS04195	COG3188	usher protein
IC568_RS04200	COG3121	Chaperone
IC568_RS04205	COG3539	Fimbrial protein
IC568_RS04215	COG4974	Belongs to the 'phage' integrase family
IC568_RS04220	COG0582	viral genome integration into host DNA
IC568_RS04225	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IC568_RS04230	COG1846	Transcriptional regulator
IC568_RS04235	COG0697	spore germination
IC568_RS04285	COG0667	Aldo Keto reductase
IC568_RS04290	COG0814	amino acid
IC568_RS04305	COG0183	Belongs to the thiolase family
IC568_RS04315	COG0823	Involved in the tonB-independent uptake of proteins
IC568_RS04320	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS04325	COG2814	Major facilitator Superfamily
IC568_RS04360	COG3842	ATPase activity
IC568_RS04365	COG0395	ABC-type sugar transport system, permease component
IC568_RS04370	COG1175	transmembrane transport
IC568_RS04375	COG1917	Cupin 2, conserved barrel domain protein
IC568_RS04380	COG1794	racemase activity, acting on amino acids and derivatives
IC568_RS04385	COG0583	DNA-binding transcription factor activity
IC568_RS04395	COG1609	Transcriptional regulator
IC568_RS04400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC568_RS04405	COG2723	6-phospho-beta-galactosidase activity
IC568_RS04410	COG2186	Transcriptional regulator
IC568_RS04420	COG1609	Transcriptional regulator
IC568_RS04440	COG0667	Aldo Keto reductase
IC568_RS04450	COG0861	Integral membrane protein TerC family
IC568_RS04485	COG2165	general secretion pathway protein
IC568_RS04490	COG4795	General secretion pathway protein
IC568_RS04500	COG4967	type IV pilus modification protein PilV
IC568_RS04505	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC568_RS04510	COG1025	Belongs to the peptidase M16 family
IC568_RS04515	COG1074	ATP-dependent DNA helicase activity
IC568_RS04520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC568_RS04530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC568_RS04530	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC568_RS04535	COG0860	N-Acetylmuramoyl-L-alanine amidase
IC568_RS04540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IC568_RS04570	COG4656	Part of a membrane complex involved in electron transport
IC568_RS04575	COG1454	alcohol dehydrogenase
IC568_RS04575	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS04590	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
IC568_RS04605	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
IC568_RS04770	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IC568_RS04775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC568_RS04780	COG2166	iron-sulfur cluster assembly
IC568_RS04785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC568_RS04795	COG0583	DNA-binding transcription factor activity
IC568_RS04800	COG2363	Small membrane protein
IC568_RS04810	COG1349	DNA-binding transcription factor activity
IC568_RS04830	COG0738	Major facilitator superfamily
IC568_RS04835	COG0235	Class ii aldolase
IC568_RS04840	COG1454	alcohol dehydrogenase
IC568_RS04860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC568_RS04875	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC568_RS04880	COG2011	ABC-type metal ion transport system permease component
IC568_RS04885	COG1464	Belongs to the NlpA lipoprotein family
IC568_RS04890	COG0477	Major facilitator Superfamily
IC568_RS04900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC568_RS04905	COG1760	l-serine dehydratase
IC568_RS04910	COG0814	amino acid
IC568_RS04915	COG1611	Belongs to the LOG family
IC568_RS04930	COG3098	single-species biofilm formation
IC568_RS04935	COG0564	pseudouridine synthase activity
IC568_RS04940	COG0716	FMN binding
IC568_RS04945	COG2271	Major facilitator Superfamily
IC568_RS04950	COG4948	Mandelate Racemase Muconate Lactonizing
IC568_RS04955	COG4948	Mandelate Racemase Muconate Lactonizing
IC568_RS04960	COG1929	Belongs to the glycerate kinase type-1 family
IC568_RS04965	COG4999	Histidine kinase
IC568_RS04965	COG3850	Histidine kinase
IC568_RS04965	COG2205	protein histidine kinase activity
IC568_RS04965	COG3437	response regulator, receiver
IC568_RS04975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC568_RS04980	COG3956	TIGRFAM MazG family protein
IC568_RS05000	COG0602	queuosine metabolic process
IC568_RS05005	COG0720	synthase
IC568_RS05025	COG2234	aminopeptidase activity
IC568_RS05085	COG1388	LysM domain
IC568_RS05085	COG4942	peptidase
IC568_RS05090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IC568_RS05115	COG0163	prenyltransferase activity
IC568_RS05120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IC568_RS05160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC568_RS05165	COG4558	Periplasmic binding protein
IC568_RS05170	COG3720	iron ion transport
IC568_RS05190	COG0679	Auxin Efflux Carrier
IC568_RS05205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC568_RS05210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC568_RS05215	COG1121	(ABC) transporter
IC568_RS05225	COG1609	Transcriptional regulator
IC568_RS05230	COG1940	carbohydrate kinase activity
IC568_RS05235	COG1447	Phosphotransferase system cellobiose-specific component IIA
IC568_RS05240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC568_RS05245	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC568_RS05250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC568_RS05255	COG4580	involved in the transport of maltose and maltodextrins
IC568_RS05265	COG2723	6-phospho-beta-galactosidase activity
IC568_RS05275	COG0309	Hydrogenase expression formation protein (HypE)
IC568_RS05280	COG0409	Hydrogenase expression formation protein
IC568_RS05285	COG0298	carbon dioxide binding
IC568_RS05290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IC568_RS05305	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC568_RS05310	COG0651	ATP synthesis coupled electron transport
IC568_RS05315	COG0650	Formate hydrogenlyase subunit 4
IC568_RS05320	COG3261	NADH dehydrogenase
IC568_RS05320	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IC568_RS05325	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC568_RS05330	COG3260	NADH ubiquinone oxidoreductase 20
IC568_RS05340	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IC568_RS05350	COG2723	6-phospho-beta-galactosidase activity
IC568_RS05355	COG1263	PTS System
IC568_RS05355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC568_RS05360	COG1609	Transcriptional regulator
IC568_RS05365	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC568_RS05370	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IC568_RS05375	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
IC568_RS05400	COG1349	DNA-binding transcription factor activity
IC568_RS05405	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS05410	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS05420	COG3732	PTS system glucitol sorbitol-specific
IC568_RS05425	COG3730	PTS system glucitol sorbitol-specific
IC568_RS05430	COG2951	lytic endotransglycosylase activity
IC568_RS05435	COG1121	(ABC) transporter
IC568_RS05440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC568_RS05445	COG0803	Belongs to the bacterial solute-binding protein 9 family
IC568_RS05450	COG1546	Belongs to the CinA family
IC568_RS05470	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IC568_RS05500	COG2823	Periplasmic or secreted lipoprotein
IC568_RS05505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC568_RS05510	COG1238	metal cluster binding
IC568_RS05530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC568_RS05535	COG2814	Major facilitator Superfamily
IC568_RS05540	COG1566	PFAM secretion protein HlyD family protein
IC568_RS05545	COG1846	Transcriptional regulator
IC568_RS05555	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC568_RS05565	COG4176	ABC-type proline glycine betaine transport system permease component
IC568_RS05580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC568_RS05590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC568_RS05595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC568_RS05600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC568_RS05605	COG4575	ribosome binding
IC568_RS05620	COG2916	Histone family protein nucleoid-structuring protein H-NS
IC568_RS05635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IC568_RS05640	COG0640	Transcriptional regulator
IC568_RS05650	COG0583	DNA-binding transcription factor activity
IC568_RS05655	COG3284	Transcriptional regulator
IC568_RS05665	COG3539	Fimbrial protein
IC568_RS05670	COG3121	Chaperone
IC568_RS05690	COG3188	usher protein
IC568_RS05700	COG3539	Fimbrial protein
IC568_RS05705	COG2197	response regulator
IC568_RS05720	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS05730	COG0235	Class ii aldolase
IC568_RS05740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC568_RS05775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC568_RS05780	COG2207	Transcriptional regulator
IC568_RS05780	COG3708	Transcriptional regulator
IC568_RS05845	COG2867	negative regulation of translational initiation
IC568_RS05860	COG0497	DNA recombination
IC568_RS05875	COG4536	flavin adenine dinucleotide binding
IC568_RS05880	COG4137	Cytochrome C assembly protein
IC568_RS05885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC568_RS05920	COG2885	chlorophyll binding
IC568_RS05925	COG2199	diguanylate cyclase activity
IC568_RS05935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC568_RS05940	COG0287	Prephenate dehydrogenase
IC568_RS05940	COG1605	Chorismate mutase
IC568_RS05950	COG0077	Prephenate dehydratase
IC568_RS05950	COG1605	Chorismate mutase
IC568_RS05960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IC568_RS05965	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC568_RS05980	COG0542	response to heat
IC568_RS06005	COG0477	Major facilitator Superfamily
IC568_RS06010	COG5544	Lipoprotein
IC568_RS06015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC568_RS06025	COG3148	PFAM DTW domain containing protein
IC568_RS06030	COG3118	belongs to the thioredoxin family
IC568_RS06035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC568_RS06050	COG0513	Belongs to the DEAD box helicase family
IC568_RS06060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IC568_RS06075	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
IC568_RS06080	COG3026	antisigma factor binding
IC568_RS06085	COG3086	response to oxidative stress
IC568_RS06095	COG0681	Belongs to the peptidase S26 family
IC568_RS06115	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC568_RS06125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC568_RS06130	COG1737	Transcriptional regulator
IC568_RS06135	COG0560	Phosphoserine phosphatase
IC568_RS06150	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC568_RS06150	COG0047	phosphoribosylformylglycinamidine synthase activity
IC568_RS06155	COG2205	protein histidine kinase activity
IC568_RS06160	COG3170	Tfp pilus assembly protein FimV
IC568_RS06165	COG2204	response regulator
IC568_RS06170	COG0347	Belongs to the P(II) protein family
IC568_RS06175	COG1017	nitric oxide dioxygenase activity
IC568_RS06175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC568_RS06185	COG2259	Doxx family
IC568_RS06190	COG1940	carbohydrate kinase activity
IC568_RS06195	COG0457	Tetratricopeptide repeat
IC568_RS06200	COG2814	Major facilitator Superfamily
IC568_RS06200	COG0477	Major facilitator Superfamily
IC568_RS06205	COG2017	converts alpha-aldose to the beta-anomer
IC568_RS06210	COG2814	Major facilitator Superfamily
IC568_RS06215	COG3711	transcriptional antiterminator
IC568_RS06220	COG3683	transport system, periplasmic component
IC568_RS06225	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IC568_RS06255	COG0822	iron-sulfur transferase activity
IC568_RS06275	COG0633	Ferredoxin
IC568_RS06280	COG2975	iron-sulfur cluster assembly
IC568_RS06300	COG2897	thiosulfate sulfurtransferase activity
IC568_RS06305	COG2373	Large extracellular alpha-helical protein
IC568_RS06310	COG4953	penicillin-binding protein 1C
IC568_RS06340	COG2976	Protein conserved in bacteria
IC568_RS06360	COG1645	bacterial-type flagellum-dependent swarming motility
IC568_RS06370	COG0516	GMP reductase activity
IC568_RS06370	COG0517	IMP dehydrogenase activity
IC568_RS06380	COG3119	arylsulfatase activity
IC568_RS06385	COG0641	radical SAM
IC568_RS06405	COG2200	EAL domain
IC568_RS06420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC568_RS06435	COG2723	6-phospho-beta-galactosidase activity
IC568_RS06445	COG2233	PERMEase
IC568_RS06460	COG1393	Belongs to the ArsC family
IC568_RS06465	COG4783	chaperone-mediated protein folding
IC568_RS06475	COG0628	permease
IC568_RS06480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC568_RS06485	COG2716	regulation of RNA biosynthetic process
IC568_RS06495	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IC568_RS06505	COG2321	neutral zinc metallopeptidase
IC568_RS06510	COG1444	tRNA N-acetyltransferase activity
IC568_RS06515	COG0400	carboxylic ester hydrolase activity
IC568_RS06530	COG1393	Belongs to the ArsC family
IC568_RS06540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC568_RS06545	COG0493	'glutamate synthase
IC568_RS06545	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC568_RS06555	COG5342	invasion associated locus B
IC568_RS06560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC568_RS06565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC568_RS06575	COG4810	utilization protein
IC568_RS06665	COG0860	N-Acetylmuramoyl-L-alanine amidase
IC568_RS06685	COG2837	iron assimilation
IC568_RS06695	COG4150	thiosulfate binding
IC568_RS06700	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC568_RS06705	COG4208	sulfate ABC transporter
IC568_RS06710	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC568_RS06720	COG4319	ketosteroid isomerase
IC568_RS06755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC568_RS06775	COG3530	Putative quorum-sensing-regulated virulence factor
IC568_RS06780	COG0385	Bile acid
IC568_RS06785	COG0583	DNA-binding transcription factor activity
IC568_RS06815	COG3415	Transposase
IC568_RS06820	COG3415	Transposase
IC568_RS06835	COG2199	diguanylate cyclase activity
IC568_RS06835	COG2200	EAL domain
IC568_RS06840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IC568_RS06855	COG0667	Aldo Keto reductase
IC568_RS06860	COG3961	Belongs to the TPP enzyme family
IC568_RS06875	COG3279	Response regulator of the LytR AlgR family
IC568_RS06880	COG3275	phosphorelay sensor kinase activity
IC568_RS06895	COG0436	Aminotransferase
IC568_RS06905	COG2807	transmembrane transport
IC568_RS06910	COG0590	tRNA wobble adenosine to inosine editing
IC568_RS06915	COG0583	DNA-binding transcription factor activity
IC568_RS06935	COG0582	viral genome integration into host DNA
IC568_RS06980	COG1396	sequence-specific DNA binding
IC568_RS07000	COG1846	Transcriptional regulator
IC568_RS07010	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IC568_RS07015	COG1403	HNH endonuclease
IC568_RS07085	COG1802	Transcriptional regulator
IC568_RS07085	COG4626	Terminase
IC568_RS07200	COG3344	reverse transcriptase
IC568_RS07210	COG2116	formate transmembrane transporter activity
IC568_RS07215	COG2853	Lipoprotein
IC568_RS07225	COG3691	Protein conserved in bacteria
IC568_RS07240	COG2062	phosphohistidine phosphatase, SixA
IC568_RS07265	COG0730	response to heat
IC568_RS07270	COG3101	peptidyl-lysine hydroxylation
IC568_RS07285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IC568_RS07305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IC568_RS07315	COG0586	Pfam SNARE associated Golgi protein
IC568_RS07325	COG0285	dihydrofolate synthase activity
IC568_RS07330	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IC568_RS07335	COG1286	toxin biosynthetic process
IC568_RS07340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IC568_RS07345	COG0163	prenyltransferase activity
IC568_RS07370	COG4160	amino acid transport
IC568_RS07375	COG4598	ABC transporter
IC568_RS07390	COG1090	epimerase
IC568_RS07395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IC568_RS07400	COG0625	glutathione transferase activity
IC568_RS07405	COG0625	glutathione transferase activity
IC568_RS07410	COG0622	Phosphoesterase
IC568_RS07415	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IC568_RS07420	COG0280	phosphate acetyltransferase
IC568_RS07420	COG0857	belongs to the CobB CobQ family
IC568_RS07440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC568_RS07445	COG0471	metal ion transport
IC568_RS07445	COG0490	domain, Protein
IC568_RS07455	COG0436	Aminotransferase
IC568_RS07460	COG0583	DNA-binding transcription factor activity
IC568_RS07505	COG0839	Belongs to the complex I subunit 6 family
IC568_RS07515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC568_RS07520	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC568_RS07535	COG2153	protein acetylation
IC568_RS07540	COG1169	isochorismate synthase
IC568_RS07565	COG0318	PFAM AMP-dependent synthetase and ligase
IC568_RS07575	COG5464	transposase or invertase
IC568_RS07590	COG1414	Transcriptional regulator
IC568_RS07600	COG2271	Major facilitator Superfamily
IC568_RS07610	COG0247	lactate metabolic process
IC568_RS07620	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IC568_RS07625	COG2271	Major facilitator Superfamily
IC568_RS07630	COG0584	glycerophosphoryl diester phosphodiesterase
IC568_RS07635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC568_RS07660	COG0183	Belongs to the thiolase family
IC568_RS07665	COG2031	fatty acid transporter
IC568_RS07670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC568_RS07675	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC568_RS07680	COG2204	response regulator
IC568_RS07685	COG3852	Histidine kinase
IC568_RS07690	COG2205	protein histidine kinase activity
IC568_RS07690	COG0784	Response regulator, receiver
IC568_RS07700	COG2198	Histidine kinase
IC568_RS07700	COG0642	Histidine kinase
IC568_RS07715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC568_RS07715	COG2169	Transcriptional regulator
IC568_RS07720	COG3145	DNA-N1-methyladenine dioxygenase activity
IC568_RS07725	COG4615	Cyclic peptide transporter
IC568_RS07730	COG2239	Acts as a magnesium transporter
IC568_RS07735	COG0659	secondary active sulfate transmembrane transporter activity
IC568_RS07750	COG0628	permease
IC568_RS07775	COG1349	DNA-binding transcription factor activity
IC568_RS07780	COG0494	nUDIX hydrolase
IC568_RS07800	COG1061	Type III restriction enzyme res subunit
IC568_RS07805	COG1187	pseudouridine synthase activity
IC568_RS07810	COG2814	Major facilitator Superfamily
IC568_RS07820	COG4172	Belongs to the ABC transporter superfamily
IC568_RS07825	COG4239	(ABC) transporter, permease
IC568_RS07830	COG4174	ABC transporter (Permease)
IC568_RS07835	COG4166	transmembrane transport
IC568_RS07840	COG2200	EAL domain
IC568_RS07845	COG0791	NLP P60 protein
IC568_RS07850	COG0671	phosphoesterase, PA-phosphatase related
IC568_RS07855	COG0523	cobalamin synthesis protein
IC568_RS07860	COG0246	Mannitol dehydrogenase
IC568_RS07865	COG1312	Catalyzes the dehydration of D-mannonate
IC568_RS07885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS07885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS07890	COG1105	Belongs to the carbohydrate kinase PfkB family
IC568_RS07895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC568_RS07895	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC568_RS07895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC568_RS07905	COG2855	membrane
IC568_RS07910	COG0583	DNA-binding transcription factor activity
IC568_RS07915	COG0833	amino acid
IC568_RS07920	COG4771	TonB-dependent receptor
IC568_RS07935	COG2311	Membrane
IC568_RS07950	COG1129	ABC transporter
IC568_RS07960	COG2949	membrane
IC568_RS07970	COG1346	cytolysis
IC568_RS07980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC568_RS07985	COG3659	wide pore channel activity
IC568_RS08000	COG2723	6-phospho-beta-galactosidase activity
IC568_RS08005	COG1538	Outer membrane efflux protein
IC568_RS08010	COG0586	Pfam SNARE associated Golgi protein
IC568_RS08020	COG1686	Belongs to the peptidase S11 family
IC568_RS08030	COG0277	FAD linked oxidase domain protein
IC568_RS08035	COG1472	Belongs to the glycosyl hydrolase 3 family
IC568_RS08040	COG1732	Glycine betaine
IC568_RS08045	COG1174	glycine betaine transport
IC568_RS08050	COG1125	glycine betaine transport
IC568_RS08055	COG1174	glycine betaine transport
IC568_RS08065	COG3275	phosphorelay sensor kinase activity
IC568_RS08075	COG4807	Protein conserved in bacteria
IC568_RS08095	COG5455	response to cobalt ion
IC568_RS08100	COG0583	DNA-binding transcription factor activity
IC568_RS08105	COG2252	PERMEase
IC568_RS08115	COG0583	DNA-binding transcription factor activity
IC568_RS08130	COG0351	phosphomethylpyrimidine kinase
IC568_RS08135	COG1830	Aldolase
IC568_RS08170	COG1070	Carbohydrate kinase
IC568_RS08180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC568_RS08185	COG4948	Mandelate Racemase Muconate Lactonizing
IC568_RS08190	COG0747	negative chemotaxis
IC568_RS08195	COG0601	transmembrane transport
IC568_RS08200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC568_RS08205	COG0444	Belongs to the ABC transporter superfamily
IC568_RS08210	COG4608	Belongs to the ABC transporter superfamily
IC568_RS08220	COG0826	peptidase U32
IC568_RS08225	COG0745	RESPONSE REGULATOR receiver
IC568_RS08230	COG2205	protein histidine kinase activity
IC568_RS08255	COG1301	dicarboxylic acid transport
IC568_RS08275	COG5002	protein histidine kinase activity
IC568_RS08280	COG0443	Heat shock 70 kDa protein
IC568_RS08285	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IC568_RS08300	COG2982	Protein involved in outer membrane biogenesis
IC568_RS08305	COG1253	flavin adenine dinucleotide binding
IC568_RS08435	COG0438	transferase activity, transferring glycosyl groups
IC568_RS08440	COG1215	transferase activity, transferring glycosyl groups
IC568_RS08450	COG0463	Glycosyl transferase, family 2
IC568_RS08475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC568_RS08505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC568_RS08510	COG0583	DNA-binding transcription factor activity
IC568_RS08520	COG0531	amino acid
IC568_RS08525	COG0640	Transcriptional regulator
IC568_RS08530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC568_RS08535	COG2925	Exonuclease
IC568_RS08550	COG1289	transmembrane transporter activity
IC568_RS08570	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IC568_RS08580	COG1942	4-Oxalocrotonate Tautomerase
IC568_RS08585	COG0583	DNA-binding transcription factor activity
IC568_RS08590	COG0095	Lipoate-protein ligase
IC568_RS08595	COG0477	Major facilitator Superfamily
IC568_RS08605	COG5001	Diguanylate cyclase
IC568_RS08605	COG3300	MHYT domain
IC568_RS08615	COG3615	Tellurite resistance protein tehB
IC568_RS08640	COG3706	GGDEF domain
IC568_RS08660	COG2207	Transcriptional regulator
IC568_RS08675	COG1566	PFAM secretion protein HlyD family protein
IC568_RS08680	COG4977	sequence-specific DNA binding
IC568_RS08695	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS08700	COG2814	Major facilitator Superfamily
IC568_RS08715	COG1737	Transcriptional regulator
IC568_RS08730	COG0582	viral genome integration into host DNA
IC568_RS08770	COG0534	Mate efflux family protein
IC568_RS08780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC568_RS08800	COG0604	alcohol dehydrogenase
IC568_RS08805	COG1309	transcriptional regulator
IC568_RS08810	COG0025	NhaP-type Na H and K H
IC568_RS08890	COG3504	Conjugal transfer protein
IC568_RS08965	COG4771	TonB-dependent receptor
IC568_RS08970	COG1021	2,3-dihydroxybenzoate-AMP ligase
IC568_RS08990	COG2226	methyltransferase
IC568_RS08990	COG3433	isochorismatase activity
IC568_RS08990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC568_RS09005	COG1132	(ABC) transporter
IC568_RS09010	COG2814	Major facilitator Superfamily
IC568_RS09015	COG1169	isochorismate synthase
IC568_RS09020	COG0582	viral genome integration into host DNA
IC568_RS09035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC568_RS09040	COG0735	belongs to the Fur family
IC568_RS09050	COG0523	cobalamin synthesis protein
IC568_RS09075	COG0523	cobalamin synthesis protein
IC568_RS09105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC568_RS09110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC568_RS09115	COG1121	(ABC) transporter
IC568_RS09120	COG0803	Belongs to the bacterial solute-binding protein 9 family
IC568_RS09125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IC568_RS09135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IC568_RS09165	COG0803	Belongs to the bacterial solute-binding protein 9 family
IC568_RS09170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC568_RS09175	COG1121	(ABC) transporter
IC568_RS09185	COG0582	viral genome integration into host DNA
IC568_RS09205	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IC568_RS09215	COG1418	mRNA catabolic process
IC568_RS09220	COG0270	DNA (cytosine-5-)-methyltransferase activity
IC568_RS09225	COG3727	T/G mismatch-specific endonuclease activity
IC568_RS09230	COG0697	spore germination
IC568_RS09235	COG2354	Protein conserved in bacteria
IC568_RS09265	COG0366	Alpha amylase catalytic
IC568_RS09270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC568_RS09280	COG0765	amino acid transport
IC568_RS09285	COG1126	abc transporter atp-binding protein
IC568_RS09290	COG2197	response regulator
IC568_RS09300	COG2197	response regulator
IC568_RS09335	COG3012	SEC-C Motif Domain Protein
IC568_RS09335	COG3318	Belongs to the UPF0149 family
IC568_RS09340	COG0814	amino acid
IC568_RS09350	COG1528	Iron-storage protein
IC568_RS09365	COG0477	Major facilitator Superfamily
IC568_RS09375	COG2211	Major facilitator Superfamily
IC568_RS09385	COG1528	Iron-storage protein
IC568_RS09395	COG1879	ABC-type sugar transport system periplasmic component
IC568_RS09405	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS09430	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IC568_RS09440	COG3102	Protein conserved in bacteria
IC568_RS09460	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IC568_RS09465	COG1801	Protein of unknown function DUF72
IC568_RS09470	COG1335	isochorismatase
IC568_RS09480	COG0494	nUDIX hydrolase
IC568_RS09505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC568_RS09515	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IC568_RS09520	COG0739	heme binding
IC568_RS09525	COG1560	Kdo2-lipid A biosynthetic process
IC568_RS09535	COG1737	Transcriptional regulator
IC568_RS09545	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IC568_RS09550	COG0129	dihydroxy-acid dehydratase activity
IC568_RS09555	COG0800	Aldolase
IC568_RS09565	COG3141	response to X-ray
IC568_RS09570	COG2979	Protein of unknown function (DUF533)
IC568_RS09575	COG1770	oligopeptidase
IC568_RS09580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC568_RS09590	COG2372	response to copper ion
IC568_RS09595	COG1276	copper resistance
IC568_RS09610	COG2990	Protein conserved in bacteria
IC568_RS09635	COG3008	intermembrane lipid transfer
IC568_RS09640	COG2995	paraquat-inducible protein a
IC568_RS09645	COG1956	GAF domain-containing protein
IC568_RS09665	COG2814	Major facilitator Superfamily
IC568_RS09670	COG1414	Transcriptional regulator
IC568_RS09700	COG0768	penicillin binding
IC568_RS09705	COG2226	methyltransferase
IC568_RS09720	COG3716	PTS system mannose fructose sorbose family IID component
IC568_RS09725	COG3715	PTS system
IC568_RS09730	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC568_RS09730	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS09735	COG1253	flavin adenine dinucleotide binding
IC568_RS09740	COG2200	EAL domain
IC568_RS09745	COG1760	l-serine dehydratase
IC568_RS09765	COG0251	oxidation-reduction process
IC568_RS09770	COG1199	ATP-dependent helicase activity
IC568_RS09780	COG3065	identical protein binding
IC568_RS09790	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IC568_RS09800	COG2894	cell division
IC568_RS09815	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC568_RS09845	COG2719	SpoVR family
IC568_RS09870	COG1619	proteins homologs of microcin C7 resistance protein MccF
IC568_RS09880	COG4774	siderophore transport
IC568_RS09890	COG2211	Major facilitator Superfamily
IC568_RS09900	COG2308	Evidence 4 Homologs of previously reported genes of
IC568_RS09940	COG0583	DNA-binding transcription factor activity
IC568_RS09945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC568_RS09960	COG1882	Formate acetyltransferase
IC568_RS09995	COG0583	DNA-binding transcription factor activity
IC568_RS10025	COG0583	DNA-binding transcription factor activity
IC568_RS10040	COG3122	Protein conserved in bacteria
IC568_RS10060	COG2885	chlorophyll binding
IC568_RS10075	COG1388	LysM domain
IC568_RS10140	COG0012	GTP binding
IC568_RS10160	COG0659	secondary active sulfate transmembrane transporter activity
IC568_RS10190	COG2890	protein-(glutamine-N5) methyltransferase activity
IC568_RS10210	COG0387	Pfam Sodium calcium exchanger
IC568_RS10215	COG4572	Cation transport regulator
IC568_RS10220	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IC568_RS10230	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC568_RS10235	COG3707	response regulator
IC568_RS10240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC568_RS10250	COG1116	anion transmembrane transporter activity
IC568_RS10255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC568_RS10255	COG2146	nitrite reductase [NAD(P)H] activity
IC568_RS10260	COG0243	molybdopterin cofactor binding
IC568_RS10265	COG4932	domain protein
IC568_RS10270	COG2197	response regulator
IC568_RS10275	COG3850	Histidine kinase
IC568_RS10280	COG2223	nitrite transmembrane transporter activity
IC568_RS10290	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IC568_RS10295	COG1140	nitrate reductase beta subunit
IC568_RS10300	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IC568_RS10305	COG2181	nitrate reductase activity
IC568_RS10315	COG1522	sequence-specific DNA binding
IC568_RS10365	COG0788	formyltetrahydrofolate deformylase activity
IC568_RS10375	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC568_RS10380	COG0745	RESPONSE REGULATOR receiver
IC568_RS10385	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC568_RS10390	COG2916	Histone family protein nucleoid-structuring protein H-NS
IC568_RS10400	COG1435	thymidine kinase activity
IC568_RS10405	COG1454	alcohol dehydrogenase
IC568_RS10405	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS10415	COG2095	MarC family integral membrane protein
IC568_RS10420	COG4166	transmembrane transport
IC568_RS10425	COG0601	transmembrane transport
IC568_RS10430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC568_RS10435	COG0444	Belongs to the ABC transporter superfamily
IC568_RS10445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC568_RS10465	COG2353	YceI-like domain
IC568_RS10475	COG2350	Protein conserved in bacteria
IC568_RS10525	COG3001	Fructosamine kinase
IC568_RS10535	COG1105	Belongs to the carbohydrate kinase PfkB family
IC568_RS10540	COG3137	Salt-induced outer membrane protein
IC568_RS10580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC568_RS10580	COG0072	phenylalanine-tRNA ligase activity
IC568_RS10600	COG0583	DNA-binding transcription factor activity
IC568_RS10620	COG0386	Belongs to the glutathione peroxidase family
IC568_RS10630	COG0791	NLP P60 protein
IC568_RS10640	COG4256	Hemin uptake protein
IC568_RS10645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC568_RS10660	COG0574	Belongs to the PEP-utilizing enzyme family
IC568_RS10660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC568_RS10670	COG0628	permease
IC568_RS10675	COG0247	lactate metabolic process
IC568_RS10675	COG0277	FAD linked oxidase domain protein
IC568_RS10680	COG2050	protein possibly involved in aromatic compounds catabolism
IC568_RS10685	COG2261	transglycosylase associated protein
IC568_RS10710	COG1120	ATPase activity
IC568_RS10715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC568_RS10725	COG0583	DNA-binding transcription factor activity
IC568_RS10750	COG1304	FMN binding
IC568_RS10755	COG1309	transcriptional regulator
IC568_RS10775	COG0316	Belongs to the HesB IscA family
IC568_RS10780	COG0719	Fe-S assembly protein
IC568_RS10785	COG0396	ATPase activity
IC568_RS10790	COG0719	Fe-S assembly protein
IC568_RS10805	COG1376	ErfK ybiS ycfS ynhG family protein
IC568_RS10835	COG1309	transcriptional regulator
IC568_RS10840	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IC568_RS10840	COG1082	Xylose isomerase domain protein TIM barrel
IC568_RS10845	COG2271	Major facilitator Superfamily
IC568_RS10850	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IC568_RS10860	COG1120	ATPase activity
IC568_RS10865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC568_RS10870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IC568_RS10875	COG1414	Transcriptional regulator
IC568_RS10910	COG2814	Major facilitator Superfamily
IC568_RS10930	COG0583	DNA-binding transcription factor activity
IC568_RS10935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC568_RS10955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC568_RS10960	COG1116	anion transmembrane transporter activity
IC568_RS10965	COG4774	siderophore transport
IC568_RS10970	COG1120	ATPase activity
IC568_RS10975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC568_RS10980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC568_RS11000	COG0765	amino acid transport
IC568_RS11005	COG1126	abc transporter atp-binding protein
IC568_RS11045	COG3383	formate dehydrogenase (NAD+) activity
IC568_RS11050	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IC568_RS11060	COG1175	transmembrane transport
IC568_RS11090	COG4133	protoheme IX ABC transporter activity
IC568_RS11095	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IC568_RS11100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IC568_RS11115	COG1138	Cytochrome C-type biogenesis protein
IC568_RS11120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IC568_RS11125	COG4235	cytochrome complex assembly
IC568_RS11125	COG3088	subunit of a heme lyase
IC568_RS11145	COG5002	protein histidine kinase activity
IC568_RS11145	COG3850	Histidine kinase
IC568_RS11150	COG0745	RESPONSE REGULATOR receiver
IC568_RS11160	COG3039	Transposase
IC568_RS11170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC568_RS11200	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS11205	COG2610	gluconate transmembrane transporter activity
IC568_RS11210	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC568_RS11220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC568_RS11230	COG0583	DNA-binding transcription factor activity
IC568_RS11260	COG2814	Major facilitator Superfamily
IC568_RS11275	COG0277	FAD linked oxidase domain protein
IC568_RS11280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC568_RS11305	COG0402	S-adenosylhomocysteine deaminase activity
IC568_RS11340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC568_RS11350	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS11355	COG0531	amino acid
IC568_RS11385	COG4608	Belongs to the ABC transporter superfamily
IC568_RS11390	COG0444	Belongs to the ABC transporter superfamily
IC568_RS11415	COG0346	lactoylglutathione lyase activity
IC568_RS11420	COG1349	DNA-binding transcription factor activity
IC568_RS11455	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IC568_RS11475	COG0300	oxidoreductase activity
IC568_RS11525	COG0307	riboflavin synthase, alpha
IC568_RS11530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC568_RS11535	COG2814	Major facilitator Superfamily
IC568_RS11540	COG0583	DNA-binding transcription factor activity
IC568_RS11555	COG2814	Major facilitator Superfamily
IC568_RS11570	COG0791	NLP P60 protein
IC568_RS11575	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC568_RS11585	COG0346	lactoylglutathione lyase activity
IC568_RS11590	COG1902	pentaerythritol trinitrate reductase activity
IC568_RS11595	COG1309	transcriptional regulator
IC568_RS11600	COG3313	Fe-S protein
IC568_RS11605	COG4989	oxidoreductase activity
IC568_RS11610	COG2032	superoxide dismutase activity
IC568_RS11615	COG1289	transmembrane transporter activity
IC568_RS11620	COG1566	PFAM secretion protein HlyD family protein
IC568_RS11635	COG3706	GGDEF domain
IC568_RS11650	COG3895	Periplasmic Protein
IC568_RS11665	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IC568_RS11670	COG0625	glutathione transferase activity
IC568_RS11680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC568_RS11690	COG4659	FMN binding
IC568_RS11725	COG2723	6-phospho-beta-galactosidase activity
IC568_RS11735	COG0673	inositol 2-dehydrogenase activity
IC568_RS11745	COG2814	Major facilitator Superfamily
IC568_RS11765	COG3038	cytochrome b561
IC568_RS11785	COG0583	DNA-binding transcription factor activity
IC568_RS11790	COG3485	protocatechuate 3,4-dioxygenase
IC568_RS11795	COG3485	protocatechuate 3,4-dioxygenase
IC568_RS11800	COG5383	Protein conserved in bacteria
IC568_RS11805	COG2272	Belongs to the type-B carboxylesterase lipase family
IC568_RS11820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC568_RS11825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC568_RS11830	COG1275	C4-dicarboxylate transporter malic acid transport protein
IC568_RS11835	COG0500	methyltransferase
IC568_RS11845	COG0697	spore germination
IC568_RS11850	COG2207	Transcriptional regulator
IC568_RS11850	COG3708	Transcriptional regulator
IC568_RS11855	COG3135	benzoate transporter
IC568_RS11860	COG1396	sequence-specific DNA binding
IC568_RS11870	COG0826	peptidase U32
IC568_RS11890	COG1294	oxidase, subunit
IC568_RS11895	COG1271	oxidase subunit
IC568_RS11900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC568_RS11905	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IC568_RS11910	COG3842	ATPase activity
IC568_RS11915	COG1176	ABC-type spermidine putrescine transport system, permease component I
IC568_RS11920	COG1177	transmembrane transport
IC568_RS11925	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS11935	COG3039	Transposase
IC568_RS11965	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS11975	COG0747	negative chemotaxis
IC568_RS11985	COG3238	Protein conserved in bacteria
IC568_RS11990	COG1247	-acetyltransferase
IC568_RS12000	COG2130	NADP-dependent
IC568_RS12015	COG3691	Protein conserved in bacteria
IC568_RS12020	COG1228	amidohydrolase
IC568_RS12025	COG4772	TonB-dependent receptor
IC568_RS12050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IC568_RS12055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC568_RS12060	COG1473	amidohydrolase
IC568_RS12065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC568_RS12070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC568_RS12080	COG0765	amino acid transport
IC568_RS12085	COG1126	abc transporter atp-binding protein
IC568_RS12095	COG0625	glutathione transferase activity
IC568_RS12105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC568_RS12110	COG3842	ATPase activity
IC568_RS12115	COG1840	ABC-type Fe3 transport system, periplasmic component
IC568_RS12120	COG1178	ABC-type Fe3 transport system permease component
IC568_RS12125	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IC568_RS12135	COG2181	nitrate reductase activity
IC568_RS12140	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IC568_RS12145	COG1140	nitrate reductase beta subunit
IC568_RS12150	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IC568_RS12170	COG1414	Transcriptional regulator
IC568_RS12175	COG4948	Mandelate Racemase Muconate Lactonizing
IC568_RS12180	COG4829	muconolactone delta-isomerase
IC568_RS12185	COG3485	protocatechuate 3,4-dioxygenase
IC568_RS12195	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC568_RS12220	COG0437	4 iron, 4 sulfur cluster binding
IC568_RS12225	COG2864	formate dehydrogenase
IC568_RS12240	COG2326	polyphosphate kinase activity
IC568_RS12250	COG2814	Major facilitator Superfamily
IC568_RS12260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC568_RS12270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC568_RS12280	COG0747	negative chemotaxis
IC568_RS12285	COG1064	alcohol dehydrogenase
IC568_RS12300	COG0488	(ABC) transporter
IC568_RS12345	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS12350	COG3729	General stress protein
IC568_RS12360	COG3685	Protein conserved in bacteria
IC568_RS12370	COG0366	Alpha amylase catalytic
IC568_RS12380	COG2323	membrane
IC568_RS12390	COG3111	PFAM Bacterial OB fold (BOF) protein
IC568_RS12400	COG1764	response to oxidative stress
IC568_RS12425	COG3781	membrane
IC568_RS12430	COG0243	molybdopterin cofactor binding
IC568_RS12435	COG0583	DNA-binding transcription factor activity
IC568_RS12440	COG2814	Major facilitator Superfamily
IC568_RS12445	COG1285	pathogenesis
IC568_RS12450	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC568_RS12460	COG0583	DNA-binding transcription factor activity
IC568_RS12480	COG0519	Catalyzes the synthesis of GMP from XMP
IC568_RS12480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC568_RS12520	COG0596	Alpha beta hydrolase
IC568_RS12530	COG2205	protein histidine kinase activity
IC568_RS12545	COG0076	glutamate decarboxylase activity
IC568_RS12550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC568_RS12555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC568_RS12560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC568_RS12565	COG1116	anion transmembrane transporter activity
IC568_RS12570	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC568_RS12580	COG0673	inositol 2-dehydrogenase activity
IC568_RS12590	COG1609	Transcriptional regulator
IC568_RS12595	COG3706	GGDEF domain
IC568_RS12600	COG0402	S-adenosylhomocysteine deaminase activity
IC568_RS12605	COG1953	Uracil, thiamine, allantoin
IC568_RS12640	COG0406	alpha-ribazole phosphatase activity
IC568_RS12645	COG1335	isochorismatase
IC568_RS12660	COG2207	Transcriptional regulator
IC568_RS12700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IC568_RS12745	COG0765	amino acid transport
IC568_RS12755	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC568_RS12765	COG2070	2-Nitropropane dioxygenase
IC568_RS12770	COG0583	DNA-binding transcription factor activity
IC568_RS12780	COG1902	pentaerythritol trinitrate reductase activity
IC568_RS12785	COG4529	Protein conserved in bacteria
IC568_RS12790	COG0477	Major facilitator Superfamily
IC568_RS12820	COG2223	nitrite transmembrane transporter activity
IC568_RS12830	COG1609	Transcriptional regulator
IC568_RS12835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS12845	COG3037	sugar-specific permease SgaT UlaA
IC568_RS12850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC568_RS12870	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC568_RS12875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC568_RS12875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC568_RS12875	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC568_RS12890	COG0583	DNA-binding transcription factor activity
IC568_RS12895	COG0583	DNA-binding transcription factor activity
IC568_RS12900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC568_RS12910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IC568_RS12925	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS12935	COG1609	Transcriptional regulator
IC568_RS12965	COG1652	LysM domain
IC568_RS12990	COG0456	acetyltransferase
IC568_RS12990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC568_RS13000	COG0667	Aldo Keto reductase
IC568_RS13005	COG0667	Aldo Keto reductase
IC568_RS13010	COG3386	PFAM SMP-30 Gluconolaconase
IC568_RS13015	COG0667	Aldo Keto reductase
IC568_RS13030	COG2801	Transposase and inactivated derivatives
IC568_RS13040	COG1473	amidohydrolase
IC568_RS13055	COG0251	oxidation-reduction process
IC568_RS13060	COG0583	DNA-binding transcription factor activity
IC568_RS13065	COG0626	cystathionine gamma-synthase activity
IC568_RS13070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC568_RS13075	COG0814	amino acid
IC568_RS13080	COG0583	DNA-binding transcription factor activity
IC568_RS13090	COG1294	oxidase, subunit
IC568_RS13095	COG1271	oxidase subunit
IC568_RS13105	COG3118	belongs to the thioredoxin family
IC568_RS13135	COG0583	DNA-binding transcription factor activity
IC568_RS13175	COG1929	Belongs to the glycerate kinase type-1 family
IC568_RS13180	COG3835	regulator
IC568_RS13200	COG2186	Transcriptional regulator
IC568_RS13205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC568_RS13205	COG1263	PTS System
IC568_RS13215	COG2814	Major facilitator Superfamily
IC568_RS13220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS13220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS13235	COG2819	hydrolase of the alpha beta superfamily
IC568_RS13240	COG3300	MHYT domain
IC568_RS13240	COG5001	Diguanylate cyclase
IC568_RS13275	COG3188	usher protein
IC568_RS13285	COG1649	PFAM Uncharacterised BCR, COG1649
IC568_RS13290	COG3550	peptidyl-serine autophosphorylation
IC568_RS13295	COG1396	sequence-specific DNA binding
IC568_RS13300	COG2351	hydroxyisourate hydrolase activity
IC568_RS13305	COG3195	allantoin biosynthetic process
IC568_RS13305	COG3648	Uricase
IC568_RS13340	COG2207	Transcriptional regulator
IC568_RS13355	COG4628	conserved protein (DUF2132)
IC568_RS13375	COG2011	ABC-type metal ion transport system permease component
IC568_RS13380	COG2070	2-Nitropropane dioxygenase
IC568_RS13390	COG0477	Major facilitator Superfamily
IC568_RS13460	COG2199	diguanylate cyclase activity
IC568_RS13475	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS13480	COG0583	DNA-binding transcription factor activity
IC568_RS13490	COG0039	L-malate dehydrogenase activity
IC568_RS13495	COG1349	DNA-binding transcription factor activity
IC568_RS13500	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC568_RS13505	COG3395	kinase activity
IC568_RS13515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC568_RS13530	COG2731	YhcH YjgK YiaL family protein
IC568_RS13535	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS13565	COG4977	sequence-specific DNA binding
IC568_RS13575	COG0697	spore germination
IC568_RS13580	COG2814	Major facilitator Superfamily
IC568_RS13595	COG1129	ABC transporter
IC568_RS13610	COG0683	leucine binding
IC568_RS13615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IC568_RS13650	COG2223	nitrite transmembrane transporter activity
IC568_RS13655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC568_RS13670	COG1349	DNA-binding transcription factor activity
IC568_RS13675	COG2084	Dehydrogenase
IC568_RS13680	COG3395	kinase activity
IC568_RS13685	COG0235	Class ii aldolase
IC568_RS13690	COG3622	Belongs to the hyi family
IC568_RS13695	COG2610	gluconate transmembrane transporter activity
IC568_RS13700	COG3708	Transcriptional regulator
IC568_RS13700	COG2207	Transcriptional regulator
IC568_RS13715	COG2200	EAL domain
IC568_RS13720	COG1546	Belongs to the CinA family
IC568_RS13725	COG0071	Belongs to the small heat shock protein (HSP20) family
IC568_RS13745	COG2197	response regulator
IC568_RS13755	COG2135	peptidase activity
IC568_RS13760	COG2207	Transcriptional regulator
IC568_RS13775	COG4221	oxidoreductase activity
IC568_RS13780	COG1802	Transcriptional regulator
IC568_RS13785	COG0589	response to stress
IC568_RS13790	COG0246	Mannitol dehydrogenase
IC568_RS13795	COG2271	Major facilitator Superfamily
IC568_RS13810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC568_RS13825	COG0243	molybdopterin cofactor binding
IC568_RS13830	COG0437	4 iron, 4 sulfur cluster binding
IC568_RS13835	COG3302	dmso reductase anchor subunit
IC568_RS13850	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IC568_RS13855	COG1940	carbohydrate kinase activity
IC568_RS13860	COG0583	DNA-binding transcription factor activity
IC568_RS13865	COG2814	Major facilitator Superfamily
IC568_RS13870	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IC568_RS13880	COG3591	Belongs to the peptidase S1B family
IC568_RS13900	COG0628	permease
IC568_RS13940	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC568_RS13965	COG3290	protein histidine kinase activity
IC568_RS13970	COG4565	transcriptional regulatory protein
IC568_RS13990	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC568_RS13990	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC568_RS14000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC568_RS14005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC568_RS14015	COG0183	Belongs to the thiolase family
IC568_RS14020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC568_RS14030	COG1414	Transcriptional regulator
IC568_RS14035	COG2840	Smr protein MutS2
IC568_RS14040	COG0583	DNA-binding transcription factor activity
IC568_RS14050	COG1473	amidohydrolase
IC568_RS14055	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IC568_RS14070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC568_RS14085	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IC568_RS14090	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IC568_RS14105	COG0531	amino acid
IC568_RS14115	COG3136	membrane protein required for alginate biosynthesis
IC568_RS14120	COG0745	RESPONSE REGULATOR receiver
IC568_RS14130	COG2205	protein histidine kinase activity
IC568_RS14140	COG0114	fumarate hydratase activity
IC568_RS14145	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC568_RS14145	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC568_RS14150	COG1482	cell wall glycoprotein biosynthetic process
IC568_RS14155	COG5339	Protein conserved in bacteria
IC568_RS14160	COG1609	Transcriptional regulator
IC568_RS14165	COG1263	PTS System
IC568_RS14165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC568_RS14170	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IC568_RS14200	COG0425	Belongs to the sulfur carrier protein TusA family
IC568_RS14205	COG5562	phage envelope protein
IC568_RS14210	COG0401	homolog of Blt101
IC568_RS14215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC568_RS14220	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS14230	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IC568_RS14235	COG0477	Major facilitator Superfamily
IC568_RS14240	COG1113	amino acid transport
IC568_RS14245	COG2988	succinylglutamate desuccinylase activity
IC568_RS14250	COG3724	N-succinylarginine dihydrolase activity
IC568_RS14255	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS14260	COG3138	arginine N-succinyltransferase
IC568_RS14265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC568_RS14275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC568_RS14280	COG0667	Aldo Keto reductase
IC568_RS14285	COG0583	DNA-binding transcription factor activity
IC568_RS14310	COG4122	O-methyltransferase activity
IC568_RS14315	COG1643	Atp-dependent helicase
IC568_RS14330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC568_RS14335	COG3327	negative regulation of DNA-templated transcription, initiation
IC568_RS14340	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC568_RS14345	COG0183	Belongs to the thiolase family
IC568_RS14350	COG2050	protein possibly involved in aromatic compounds catabolism
IC568_RS14355	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC568_RS14360	COG1024	Enoyl-CoA hydratase
IC568_RS14365	COG1024	Enoyl-CoA hydratase
IC568_RS14370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC568_RS14375	COG2151	metal-sulfur cluster biosynthetic enzyme
IC568_RS14380	COG3396	Phenylacetate-CoA oxygenase
IC568_RS14385	COG3460	Phenylacetate-CoA oxygenase
IC568_RS14390	COG3396	Phenylacetate-CoA oxygenase
IC568_RS14395	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS14395	COG2030	dehydratase
IC568_RS14415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IC568_RS14430	COG2072	flavoprotein involved in K transport
IC568_RS14435	COG0583	DNA-binding transcription factor activity
IC568_RS14440	COG1126	abc transporter atp-binding protein
IC568_RS14450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC568_RS14465	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS14470	COG2207	Transcriptional regulator
IC568_RS14475	COG3784	Protein of unknown function (DUF1318)
IC568_RS14485	COG2911	Protein conserved in bacteria
IC568_RS14490	COG0586	Pfam SNARE associated Golgi protein
IC568_RS14495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IC568_RS14500	COG3187	Heat shock protein
IC568_RS14505	COG3042	response to heat
IC568_RS14510	COG1013	pyruvate-flavodoxin oxidoreductase activity
IC568_RS14510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC568_RS14510	COG0674	pyruvate-flavodoxin oxidoreductase activity
IC568_RS14510	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IC568_RS14515	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IC568_RS14525	COG0589	response to stress
IC568_RS14535	COG0513	Belongs to the DEAD box helicase family
IC568_RS14545	COG1349	DNA-binding transcription factor activity
IC568_RS14550	COG0673	inositol 2-dehydrogenase activity
IC568_RS14565	COG1113	amino acid transport
IC568_RS14570	COG1522	sequence-specific DNA binding
IC568_RS14580	COG1448	Aminotransferase
IC568_RS14585	COG2011	ABC-type metal ion transport system permease component
IC568_RS14600	COG0436	Aminotransferase
IC568_RS14635	COG0583	DNA-binding transcription factor activity
IC568_RS14655	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS14660	COG1309	transcriptional regulator
IC568_RS14665	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS14785	COG2885	chlorophyll binding
IC568_RS14810	COG0693	protein deglycase activity
IC568_RS14815	COG1078	dGTPase activity
IC568_RS14820	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS14825	COG0583	DNA-binding transcription factor activity
IC568_RS14840	COG0656	L-ascorbic acid biosynthetic process
IC568_RS14865	COG4166	transmembrane transport
IC568_RS14875	COG2866	Carboxypeptidase
IC568_RS14880	COG4948	Mandelate Racemase Muconate Lactonizing
IC568_RS14885	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IC568_RS14890	COG3180	Ammonia monooxygenase
IC568_RS14900	COG1486	melibiose metabolic process
IC568_RS14905	COG0583	DNA-binding transcription factor activity
IC568_RS14915	COG3106	COG3106 Predicted ATPase
IC568_RS14925	COG1983	PspC domain protein
IC568_RS14935	COG1842	Phage shock protein A
IC568_RS14940	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IC568_RS14950	COG1473	amidohydrolase
IC568_RS14965	COG0702	epimerase
IC568_RS14980	COG4171	peptide transport system, permease
IC568_RS14995	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC568_RS15005	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IC568_RS15010	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC568_RS15010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC568_RS15025	COG1349	DNA-binding transcription factor activity
IC568_RS15035	COG0023	Translation Initiation Factor
IC568_RS15045	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IC568_RS15050	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IC568_RS15055	COG0671	phosphoesterase, PA-phosphatase related
IC568_RS15065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC568_RS15075	COG3039	Transposase
IC568_RS15095	COG0616	signal peptide processing
IC568_RS15105	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS15110	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IC568_RS15120	COG0583	DNA-binding transcription factor activity
IC568_RS15130	COG0009	L-threonylcarbamoyladenylate synthase
IC568_RS15140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC568_RS15145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IC568_RS15145	COG0512	Glutamine amidotransferase of anthranilate synthase
IC568_RS15150	COG0134	indole-3-glycerol-phosphate synthase activity
IC568_RS15150	COG0135	phosphoribosylanthranilate isomerase activity
IC568_RS15185	COG4774	siderophore transport
IC568_RS15195	COG3047	cAMP biosynthetic process
IC568_RS15200	COG0727	PFAM Uncharacterised protein family (UPF0153)
IC568_RS15230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC568_RS15235	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS15240	COG1988	membrane-bound metal-dependent
IC568_RS15245	COG1823	symporter activity
IC568_RS15255	COG0753	catalase activity
IC568_RS15265	COG1486	melibiose metabolic process
IC568_RS15270	COG1917	Cupin 2, conserved barrel domain protein
IC568_RS15270	COG2169	Transcriptional regulator
IC568_RS15275	COG1447	Phosphotransferase system cellobiose-specific component IIA
IC568_RS15280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC568_RS15290	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC568_RS15295	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC568_RS15305	COG0322	excinuclease ABC activity
IC568_RS15310	COG3678	ATP-independent chaperone mediated protein folding
IC568_RS15320	COG3724	N-succinylarginine dihydrolase activity
IC568_RS15330	COG3138	arginine N-succinyltransferase
IC568_RS15340	COG0708	Exodeoxyribonuclease III
IC568_RS15345	COG0398	Pfam SNARE associated Golgi protein
IC568_RS15350	COG0398	Pfam SNARE associated Golgi protein
IC568_RS15355	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC568_RS15360	COG4134	Bacterial extracellular solute-binding protein
IC568_RS15365	COG4135	transport system, permease component
IC568_RS15370	COG4136	ATPase activity
IC568_RS15375	COG2897	thiosulfate sulfurtransferase activity
IC568_RS15380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC568_RS15385	COG0494	nUDIX hydrolase
IC568_RS15390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC568_RS15395	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS15395	COG3321	synthase
IC568_RS15395	COG0604	alcohol dehydrogenase
IC568_RS15400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IC568_RS15405	COG0709	Synthesizes selenophosphate from selenide and ATP
IC568_RS15415	COG0778	Nitroreductase
IC568_RS15420	COG0616	signal peptide processing
IC568_RS15425	COG0252	asparaginase activity
IC568_RS15430	COG1335	isochorismatase
IC568_RS15445	COG3139	Protein of unknown function (DUF1315)
IC568_RS15465	COG0656	L-ascorbic acid biosynthetic process
IC568_RS15470	COG3713	MltA-interacting MipA family protein
IC568_RS15475	COG2766	serine protein kinase
IC568_RS15490	COG0386	Belongs to the glutathione peroxidase family
IC568_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS15520	COG0583	DNA-binding transcription factor activity
IC568_RS15525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC568_RS15530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC568_RS15540	COG0859	PFAM glycosyl transferase family 9
IC568_RS15545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC568_RS15555	COG2207	Transcriptional regulator
IC568_RS15560	COG2807	transmembrane transport
IC568_RS15565	COG0504	CTP synthase activity
IC568_RS15570	COG1683	Conserved Protein
IC568_RS15575	COG3189	MarR family transcriptional regulator
IC568_RS15580	COG3042	response to heat
IC568_RS15585	COG2199	diguanylate cyclase activity
IC568_RS15585	COG2203	Gaf domain
IC568_RS15605	COG3182	Iron-regulated membrane protein
IC568_RS15615	COG1560	Kdo2-lipid A biosynthetic process
IC568_RS15625	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IC568_RS15630	COG3706	GGDEF domain
IC568_RS15635	COG0583	DNA-binding transcription factor activity
IC568_RS15640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IC568_RS15670	COG1294	oxidase, subunit
IC568_RS15675	COG1271	oxidase subunit
IC568_RS15680	COG3546	catalase activity
IC568_RS15685	COG3685	Protein conserved in bacteria
IC568_RS15690	COG3685	Protein conserved in bacteria
IC568_RS15695	COG3729	General stress protein
IC568_RS15700	COG1063	alcohol dehydrogenase
IC568_RS15705	COG3813	Protein conserved in bacteria
IC568_RS15730	COG0640	Transcriptional regulator
IC568_RS15735	COG0538	isocitrate dehydrogenase activity
IC568_RS15740	COG3300	MHYT domain
IC568_RS15740	COG5001	Diguanylate cyclase
IC568_RS15745	COG3706	GGDEF domain
IC568_RS15765	COG0538	isocitrate dehydrogenase activity
IC568_RS15770	COG1187	pseudouridine synthase activity
IC568_RS15790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC568_RS15810	COG2205	protein histidine kinase activity
IC568_RS15815	COG2850	peptidyl-arginine hydroxylation
IC568_RS15820	COG1943	Transposase
IC568_RS15840	COG1177	transmembrane transport
IC568_RS15855	COG0318	PFAM AMP-dependent synthetase and ligase
IC568_RS15860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC568_RS15865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC568_RS15870	COG0698	ribose 5-phosphate isomerase
IC568_RS15885	COG3395	kinase activity
IC568_RS15900	COG2390	Transcriptional regulator
IC568_RS15910	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC568_RS15920	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC568_RS15930	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC568_RS15940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IC568_RS15945	COG1376	ErfK ybiS ycfS ynhG family protein
IC568_RS15945	COG1388	LysM domain
IC568_RS15960	COG1309	transcriptional regulator
IC568_RS15975	COG3134	Outer membrane lipoprotein
IC568_RS15980	COG1252	NADH dehydrogenase
IC568_RS16005	COG5633	Lipoprotein
IC568_RS16010	COG0537	adenosine 5'-monophosphoramidase activity
IC568_RS16020	COG0084	hydrolase, TatD family'
IC568_RS16025	COG0470	DNA polymerase III
IC568_RS16035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC568_RS16040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC568_RS16045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IC568_RS16060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC568_RS16080	COG1399	metal-binding, possibly nucleic acid-binding protein
IC568_RS16100	COG1530	ribonuclease E activity
IC568_RS16105	COG0583	DNA-binding transcription factor activity
IC568_RS16110	COG2814	Major facilitator Superfamily
IC568_RS16130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC568_RS16175	COG1560	Kdo2-lipid A biosynthetic process
IC568_RS16190	COG5645	(Lipo)protein
IC568_RS16225	COG3381	protein complex oligomerization
IC568_RS16250	COG1309	transcriptional regulator
IC568_RS16255	COG0583	DNA-binding transcription factor activity
IC568_RS16265	COG1335	isochorismatase
IC568_RS16275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC568_RS16280	COG1702	phosphate starvation-inducible protein PhoH
IC568_RS16300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IC568_RS16310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC568_RS16325	COG1309	transcriptional regulator
IC568_RS16360	COG2233	PERMEase
IC568_RS16370	COG3729	General stress protein
IC568_RS16400	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS16415	COG0531	amino acid
IC568_RS16420	COG0174	glutamine synthetase
IC568_RS16425	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IC568_RS16430	COG1396	sequence-specific DNA binding
IC568_RS16430	COG1917	Cupin 2, conserved barrel domain protein
IC568_RS16435	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS16440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IC568_RS16445	COG0583	DNA-binding transcription factor activity
IC568_RS16450	COG0473	3-isopropylmalate dehydrogenase activity
IC568_RS16455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC568_RS16460	COG4638	Rieske (2fe-2S)
IC568_RS16465	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS16470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC568_RS16495	COG3039	Transposase
IC568_RS16500	COG0670	Belongs to the BI1 family
IC568_RS16515	COG2207	Transcriptional regulator
IC568_RS16520	COG1881	PFAM PEBP family protein
IC568_RS16535	COG1832	CoA-binding protein
IC568_RS16545	COG0210	DNA helicase
IC568_RS16550	COG3304	Inner membrane component domain
IC568_RS16555	COG1289	transmembrane transporter activity
IC568_RS16560	COG3070	regulator of competence-specific genes
IC568_RS16580	COG1067	ATP-dependent peptidase activity
IC568_RS16590	COG3130	regulation of translation
IC568_RS16595	COG3009	Protein conserved in bacteria
IC568_RS16600	COG3008	intermembrane lipid transfer
IC568_RS16600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC568_RS16605	COG2995	paraquat-inducible protein a
IC568_RS16610	COG0488	(ABC) transporter
IC568_RS16620	COG0633	Ferredoxin
IC568_RS16620	COG3217	Mosc domain protein beta barrel domain protein
IC568_RS16635	COG0431	NADPH-dependent FMN reductase
IC568_RS16640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC568_RS16645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC568_RS16650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC568_RS16660	COG0308	aminopeptidase N
IC568_RS16670	COG1473	amidohydrolase
IC568_RS16680	COG0814	amino acid
IC568_RS16720	COG1448	Aminotransferase
IC568_RS16725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC568_RS16730	COG3108	Peptidase M15
IC568_RS16735	COG2989	Protein conserved in bacteria
IC568_RS16745	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IC568_RS16755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC568_RS16760	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IC568_RS16765	COG3173	Aminoglycoside phosphotransferase
IC568_RS16780	COG3214	Protein conserved in bacteria
IC568_RS16795	COG2333	competence protein COMEC
IC568_RS16795	COG0658	competence protein
IC568_RS16805	COG0539	negative regulation of cytoplasmic translation
IC568_RS16825	COG2323	membrane
IC568_RS16830	COG1944	ATP diphosphatase activity
IC568_RS16835	COG2116	formate transmembrane transporter activity
IC568_RS16840	COG1882	Formate acetyltransferase
IC568_RS16845	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IC568_RS16850	COG0477	Major facilitator Superfamily
IC568_RS16855	COG3302	dmso reductase anchor subunit
IC568_RS16860	COG0437	4 iron, 4 sulfur cluster binding
IC568_RS16865	COG0243	molybdopterin cofactor binding
IC568_RS16875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC568_RS16885	COG1674	ftsk spoiiie
IC568_RS16885	COG1178	ABC-type Fe3 transport system permease component
IC568_RS16895	COG0492	ferredoxin-NADP+ reductase activity
IC568_RS16900	COG4988	ABC transporter
IC568_RS16905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IC568_RS16920	COG0542	response to heat
IC568_RS16930	COG1278	Cold shock
IC568_RS16940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC568_RS16945	COG3593	DNA synthesis involved in DNA repair
IC568_RS16955	COG2431	L-lysine efflux transmembrane transporter activity
IC568_RS16965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC568_RS16975	COG0028	Belongs to the TPP enzyme family
IC568_RS16980	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IC568_RS16985	COG0702	epimerase
IC568_RS16990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC568_RS16995	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC568_RS17000	COG4251	negative regulation of phosphorylation
IC568_RS17000	COG2203	Gaf domain
IC568_RS17000	COG5001	Diguanylate cyclase
IC568_RS17000	COG3706	GGDEF domain
IC568_RS17010	COG1126	abc transporter atp-binding protein
IC568_RS17015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC568_RS17020	COG4215	(ABC) transporter
IC568_RS17025	COG4160	amino acid transport
IC568_RS17030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC568_RS17035	COG5002	protein histidine kinase activity
IC568_RS17040	COG0745	RESPONSE REGULATOR receiver
IC568_RS17055	COG1177	transmembrane transport
IC568_RS17060	COG1176	ABC-type spermidine putrescine transport system, permease component I
IC568_RS17065	COG3842	ATPase activity
IC568_RS17070	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IC568_RS17085	COG0778	Nitroreductase
IC568_RS17205	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC568_RS17230	COG3226	Transcriptional regulator
IC568_RS17235	COG0738	Major facilitator superfamily
IC568_RS17240	COG0561	phosphatase activity
IC568_RS17245	COG2814	Major facilitator Superfamily
IC568_RS17250	COG0671	phosphoesterase, PA-phosphatase related
IC568_RS17255	COG1349	DNA-binding transcription factor activity
IC568_RS17260	COG1686	Belongs to the peptidase S11 family
IC568_RS17270	COG0625	glutathione transferase activity
IC568_RS17275	COG2133	pyrroloquinoline quinone binding
IC568_RS17285	COG2223	nitrite transmembrane transporter activity
IC568_RS17305	COG0747	negative chemotaxis
IC568_RS17320	COG0303	'Molybdopterin
IC568_RS17325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IC568_RS17330	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IC568_RS17335	COG1882	Formate acetyltransferase
IC568_RS17340	COG0561	phosphatase activity
IC568_RS17350	COG1609	Transcriptional regulator
IC568_RS17355	COG2271	Major facilitator Superfamily
IC568_RS17365	COG0488	(ABC) transporter
IC568_RS17370	COG2365	Tyrosine phosphatase family
IC568_RS17375	COG1376	ErfK ybiS ycfS ynhG family protein
IC568_RS17380	COG2188	Transcriptional regulator
IC568_RS17385	COG2723	6-phospho-beta-galactosidase activity
IC568_RS17390	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IC568_RS17405	COG2194	sulfuric ester hydrolase activity
IC568_RS17410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC568_RS17425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC568_RS17430	COG0765	amino acid transport
IC568_RS17435	COG1126	abc transporter atp-binding protein
IC568_RS17440	COG0668	transmembrane transport
IC568_RS17450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC568_RS17460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC568_RS17470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IC568_RS17475	COG1199	ATP-dependent helicase activity
IC568_RS17480	COG0513	Belongs to the DEAD box helicase family
IC568_RS17485	COG3958	Transketolase
IC568_RS17490	COG3959	Transketolase, thiamine diphosphate binding domain
IC568_RS17495	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS17500	COG2271	Major facilitator Superfamily
IC568_RS17510	COG0583	DNA-binding transcription factor activity
IC568_RS17515	COG1309	transcriptional regulator
IC568_RS17520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC568_RS17525	COG1131	(ABC) transporter
IC568_RS17530	COG0842	Transport permease protein
IC568_RS17535	COG0842	Transport permease protein
IC568_RS17545	COG3568	Endonuclease Exonuclease Phosphatase
IC568_RS17550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC568_RS17555	COG0392	lysyltransferase activity
IC568_RS17560	COG0670	Belongs to the BI1 family
IC568_RS17565	COG0314	molybdopterin synthase activity
IC568_RS17570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IC568_RS17580	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC568_RS17600	COG0745	RESPONSE REGULATOR receiver
IC568_RS17605	COG0642	Histidine kinase
IC568_RS17630	COG2226	methyltransferase
IC568_RS17645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IC568_RS17650	COG1881	PFAM PEBP family protein
IC568_RS17690	COG4677	pectinesterase activity
IC568_RS17700	COG0589	response to stress
IC568_RS17705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC568_RS17740	COG0789	Transcriptional regulator
IC568_RS17745	COG2200	EAL domain
IC568_RS17770	COG0561	phosphatase activity
IC568_RS17780	COG4149	molybdate abc transporter
IC568_RS17785	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC568_RS17795	COG3585	molybdate ion transport
IC568_RS17795	COG2005	Transcriptional regulator
IC568_RS17800	COG1119	ATPase activity
IC568_RS17810	COG1085	galactose-1-phosphate uridylyltransferase
IC568_RS17820	COG2017	converts alpha-aldose to the beta-anomer
IC568_RS17830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC568_RS17845	COG3201	nicotinamide mononucleotide transporter
IC568_RS17850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IC568_RS17900	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IC568_RS17905	COG2885	chlorophyll binding
IC568_RS17915	COG3064	Membrane
IC568_RS17920	COG0848	biopolymer transport protein
IC568_RS17925	COG0811	peptide transport
IC568_RS17930	COG0824	Thioesterase
IC568_RS17935	COG3790	cyd operon protein YbgE
IC568_RS17940	COG4890	Cyd operon protein YbgT
IC568_RS17945	COG1294	oxidase, subunit
IC568_RS17950	COG1271	oxidase subunit
IC568_RS17955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IC568_RS17965	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC568_RS17970	COG0567	Dehydrogenase, E1 component
IC568_RS17975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC568_RS17980	COG1053	succinate dehydrogenase
IC568_RS17985	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC568_RS17990	COG2009	succinate dehydrogenase
IC568_RS18025	COG1984	allophanate hydrolase subunit 2
IC568_RS18030	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IC568_RS18045	COG0415	Belongs to the DNA photolyase family
IC568_RS18075	COG2205	protein histidine kinase activity
IC568_RS18080	COG0745	RESPONSE REGULATOR receiver
IC568_RS18090	COG0033	Phosphoglucomutase
IC568_RS18100	COG0596	Alpha beta hydrolase
IC568_RS18115	COG0735	belongs to the Fur family
IC568_RS18155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IC568_RS18160	COG1940	carbohydrate kinase activity
IC568_RS18160	COG1846	Transcriptional regulator
IC568_RS18165	COG0647	UMP catabolic process
IC568_RS18170	COG0367	asparagine synthase
IC568_RS18210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC568_RS18220	COG1702	phosphate starvation-inducible protein PhoH
IC568_RS18245	COG0765	amino acid transport
IC568_RS18250	COG0765	amino acid transport
IC568_RS18255	COG1126	abc transporter atp-binding protein
IC568_RS18270	COG2888	peptidyl-tyrosine sulfation
IC568_RS18285	COG1466	dna polymerase III delta subunit
IC568_RS18300	COG0799	negative regulation of ribosome biogenesis
IC568_RS18310	COG0768	penicillin binding
IC568_RS18315	COG0772	Belongs to the SEDS family
IC568_RS18320	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IC568_RS18325	COG1686	Belongs to the peptidase S11 family
IC568_RS18340	COG0583	DNA-binding transcription factor activity
IC568_RS18355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC568_RS18375	COG3069	C4-dicarboxylate transmembrane transporter activity
IC568_RS18380	COG3719	Belongs to the RNase T2 family
IC568_RS18385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC568_RS18405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC568_RS18410	COG0583	DNA-binding transcription factor activity
IC568_RS18415	COG3969	phosphoadenosine phosphosulfate
IC568_RS18420	COG1475	DNA binding
IC568_RS18425	COG0436	Aminotransferase
IC568_RS18450	COG1129	ABC transporter
IC568_RS18455	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS18460	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS18470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC568_RS18485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC568_RS18495	COG0402	S-adenosylhomocysteine deaminase activity
IC568_RS18505	COG0483	inositol monophosphate 1-phosphatase activity
IC568_RS18510	COG2271	Major facilitator Superfamily
IC568_RS18545	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS18550	COG1129	ABC transporter
IC568_RS18555	COG0371	Dehydrogenase
IC568_RS18560	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS18575	COG2879	small protein
IC568_RS18580	COG1966	Carbon starvation protein
IC568_RS18590	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS18595	COG3433	isochorismatase activity
IC568_RS18595	COG1535	isochorismatase
IC568_RS18600	COG1021	2,3-dihydroxybenzoate-AMP ligase
IC568_RS18605	COG1169	isochorismate synthase
IC568_RS18610	COG4592	Periplasmic binding protein
IC568_RS18620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC568_RS18625	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC568_RS18630	COG1120	ATPase activity
IC568_RS18635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC568_RS18635	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC568_RS18640	COG3251	PFAM MbtH domain protein
IC568_RS18645	COG2382	esterase
IC568_RS18650	COG4771	TonB-dependent receptor
IC568_RS18655	COG2977	Belongs to the P-Pant transferase superfamily
IC568_RS18660	COG3958	Transketolase
IC568_RS18665	COG3959	Transketolase, thiamine diphosphate binding domain
IC568_RS18670	COG2390	Transcriptional regulator
IC568_RS18675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC568_RS18680	COG1879	ABC-type sugar transport system periplasmic component
IC568_RS18690	COG1129	ABC transporter
IC568_RS18695	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS18705	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS18715	COG0583	DNA-binding transcription factor activity
IC568_RS18720	COG0668	transmembrane transport
IC568_RS18730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC568_RS18755	COG0747	negative chemotaxis
IC568_RS18760	COG0601	transmembrane transport
IC568_RS18765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC568_RS18770	COG0444	Belongs to the ABC transporter superfamily
IC568_RS18775	COG4608	Belongs to the ABC transporter superfamily
IC568_RS18785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IC568_RS18790	COG4221	oxidoreductase activity
IC568_RS18800	COG4215	(ABC) transporter
IC568_RS18810	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IC568_RS18825	COG0697	spore germination
IC568_RS18840	COG4608	Belongs to the ABC transporter superfamily
IC568_RS18845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC568_RS18855	COG4166	transmembrane transport
IC568_RS18865	COG3698	Phosphodiester glycosidase
IC568_RS18880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IC568_RS18905	COG2315	Protein conserved in bacteria
IC568_RS18910	COG0778	Nitroreductase
IC568_RS18920	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC568_RS18930	COG3716	PTS system mannose fructose sorbose family IID component
IC568_RS18935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC568_RS18940	COG2222	sugar isomerase
IC568_RS18945	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IC568_RS18945	COG3933	PFAM sigma-54 factor interaction domain-containing protein
IC568_RS18960	COG0477	Major facilitator Superfamily
IC568_RS18965	COG0668	transmembrane transport
IC568_RS18970	COG1609	Transcriptional regulator
IC568_RS18990	COG2211	Major facilitator Superfamily
IC568_RS18995	COG1113	amino acid transport
IC568_RS19010	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS19015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IC568_RS19025	COG0531	amino acid
IC568_RS19040	COG4680	protein conserved in bacteria
IC568_RS19080	COG0667	Aldo Keto reductase
IC568_RS19085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC568_RS19090	COG1473	amidohydrolase
IC568_RS19120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC568_RS19125	COG1120	ATPase activity
IC568_RS19130	COG1566	PFAM secretion protein HlyD family protein
IC568_RS19175	COG4211	Belongs to the binding-protein-dependent transport system permease family
IC568_RS19180	COG1129	ABC transporter
IC568_RS19195	COG0673	inositol 2-dehydrogenase activity
IC568_RS19225	COG3104	oligopeptide transport
IC568_RS19230	COG1982	Orn Lys Arg decarboxylase major
IC568_RS19235	COG0531	amino acid
IC568_RS19240	COG3710	Transcriptional regulator
IC568_RS19250	COG1560	Kdo2-lipid A biosynthetic process
IC568_RS19265	COG3188	usher protein
IC568_RS19270	COG3121	Chaperone
IC568_RS19275	COG3539	Fimbrial protein
IC568_RS19410	COG0582	viral genome integration into host DNA
IC568_RS19565	COG3772	lysozyme
IC568_RS19735	COG2501	S4 domain
IC568_RS19745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC568_RS19760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IC568_RS19765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC568_RS19785	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IC568_RS19790	COG4181	ATPase activity
IC568_RS19795	COG2755	lipolytic protein G-D-S-L family
IC568_RS19800	COG0300	oxidoreductase activity
IC568_RS19805	COG3118	belongs to the thioredoxin family
IC568_RS19810	COG0390	transport system, permease component
IC568_RS19815	COG4619	ABC transporter
IC568_RS19820	COG0330	HflC and HflK could
IC568_RS19825	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC568_RS19840	COG3735	TraB family
IC568_RS19845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC568_RS19855	COG2223	nitrite transmembrane transporter activity
IC568_RS19860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC568_RS19860	COG4651	solute:proton antiporter activity
IC568_RS19865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC568_RS19905	COG2832	Protein of unknown function (DUF454)
IC568_RS19910	COG3923	Primosomal replication protein n
IC568_RS19920	COG5464	transposase or invertase
IC568_RS19925	COG1196	nuclear chromosome segregation
IC568_RS19925	COG3264	Mechanosensitive ion channel
IC568_RS19930	COG1309	transcriptional regulator
IC568_RS19935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC568_RS19940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC568_RS19955	COG0110	maltose O-acetyltransferase activity
IC568_RS20005	COG1874	Beta-galactosidase
IC568_RS20010	COG3867	Arabinogalactan endo-beta-1,4-galactanase
IC568_RS20015	COG3833	ABC-type maltose transport systems, permease component
IC568_RS20020	COG1175	transmembrane transport
IC568_RS20025	COG2182	Extracellular solute-binding protein
IC568_RS20035	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC568_RS20050	COG2364	Membrane
IC568_RS20080	COG3695	enzyme binding
IC568_RS20085	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IC568_RS20090	COG1946	Acyl-CoA thioesterase
IC568_RS20095	COG0004	ammonium transporteR
IC568_RS20100	COG0347	Belongs to the P(II) protein family
IC568_RS20105	COG1132	(ABC) transporter
IC568_RS20110	COG1132	(ABC) transporter
IC568_RS20115	COG1522	sequence-specific DNA binding
IC568_RS20130	COG4533	DNA binding
IC568_RS20140	COG0824	Thioesterase
IC568_RS20145	COG1555	photosystem II stabilization
IC568_RS20150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC568_RS20155	COG0776	regulation of translation
IC568_RS20160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IC568_RS20180	COG0271	Belongs to the BolA IbaG family
IC568_RS20185	COG3056	Lipoprotein
IC568_RS20190	COG2223	nitrite transmembrane transporter activity
IC568_RS20195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IC568_RS20200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC568_RS20205	COG1845	cytochrome c oxidase, subunit III
IC568_RS20210	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC568_RS20225	COG1414	Transcriptional regulator
IC568_RS20230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IC568_RS20235	COG1053	succinate dehydrogenase
IC568_RS20245	COG1053	succinate dehydrogenase
IC568_RS20260	COG0673	inositol 2-dehydrogenase activity
IC568_RS20265	COG2814	Major facilitator Superfamily
IC568_RS20275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IC568_RS20300	COG0142	geranyltranstransferase activity
IC568_RS20310	COG0667	Aldo Keto reductase
IC568_RS20315	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC568_RS20335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC568_RS20335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC568_RS20345	COG4238	major outer membrane lipoprotein
IC568_RS20365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC568_RS20370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC568_RS20375	COG1862	Preprotein translocase
IC568_RS20400	COG0450	alkyl hydroperoxide reductase
IC568_RS20405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS20420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC568_RS20430	COG1228	amidohydrolase
IC568_RS20440	COG1335	isochorismatase
IC568_RS20445	COG0583	DNA-binding transcription factor activity
IC568_RS20450	COG0366	Alpha amylase catalytic
IC568_RS20475	COG0420	3'-5' exonuclease activity
IC568_RS20480	COG0419	ATPase involved in DNA repair
IC568_RS20485	COG1940	carbohydrate kinase activity
IC568_RS20500	COG4126	flavin adenine dinucleotide binding
IC568_RS20510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IC568_RS20515	COG3416	Protein conserved in bacteria
IC568_RS20525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IC568_RS20535	COG1785	Belongs to the alkaline phosphatase family
IC568_RS20575	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC568_RS20580	COG1335	isochorismatase
IC568_RS20585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC568_RS20590	COG0113	porphobilinogen synthase activity
IC568_RS20600	COG2175	clavaminate synthase activity
IC568_RS20605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC568_RS20610	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC568_RS20615	COG4521	taurine ABC transporter
IC568_RS20620	COG2040	homocysteine
IC568_RS20625	COG0833	amino acid
IC568_RS20640	COG4303	Ethanolamine ammonia lyase large subunit
IC568_RS20645	COG4302	ethanolamine ammonia-lyase activity
IC568_RS20685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC568_RS20690	COG1126	abc transporter atp-binding protein
IC568_RS20695	COG4597	amino acid ABC transporter
IC568_RS20700	COG0765	amino acid transport
IC568_RS20715	COG3188	usher protein
IC568_RS20740	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IC568_RS20750	COG3639	organic phosphonate transmembrane transporter activity
IC568_RS20765	COG0791	NLP P60 protein
IC568_RS20795	COG0765	amino acid transport
IC568_RS20805	COG4221	oxidoreductase activity
IC568_RS20820	COG0436	Aminotransferase
IC568_RS20825	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IC568_RS20830	COG1984	allophanate hydrolase subunit 2
IC568_RS20845	COG0697	spore germination
IC568_RS20850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC568_RS20855	COG0439	Biotin carboxylase
IC568_RS20860	COG0511	ligase activity, forming carbon-carbon bonds
IC568_RS20870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC568_RS20875	COG0022	dehydrogenase e1 component
IC568_RS20880	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC568_RS20885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC568_RS20905	COG1070	Carbohydrate kinase
IC568_RS20910	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS20915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC568_RS20920	COG3775	system Galactitol-specific IIC component
IC568_RS20925	COG0625	glutathione transferase activity
IC568_RS20930	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IC568_RS20945	COG0579	oxidoreductase
IC568_RS20950	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS20955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC568_RS20960	COG1113	amino acid transport
IC568_RS20965	COG1802	Transcriptional regulator
IC568_RS20985	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC568_RS20990	COG0454	-acetyltransferase
IC568_RS21005	COG2991	Protein conserved in bacteria
IC568_RS21020	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IC568_RS21025	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IC568_RS21040	COG3034	peptidoglycan biosynthetic process
IC568_RS21045	COG0121	glutamine amidotransferase
IC568_RS21055	COG1960	acyl-CoA dehydrogenase activity
IC568_RS21060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC568_RS21070	COG0583	DNA-binding transcription factor activity
IC568_RS21080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC568_RS21090	COG2226	methyltransferase
IC568_RS21100	COG0741	lytic transglycosylase activity
IC568_RS21100	COG1388	LysM domain
IC568_RS21105	COG2226	methyltransferase
IC568_RS21115	COG2814	Major facilitator Superfamily
IC568_RS21120	COG0583	DNA-binding transcription factor activity
IC568_RS21125	COG0656	L-ascorbic acid biosynthetic process
IC568_RS21160	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IC568_RS21170	COG2011	ABC-type metal ion transport system permease component
IC568_RS21175	COG1464	Belongs to the NlpA lipoprotein family
IC568_RS21185	COG1720	tRNA m6t6A37 methyltransferase activity
IC568_RS21195	COG0791	NLP P60 protein
IC568_RS21200	COG3015	lipoprotein NlpE involved in copper resistance
IC568_RS21205	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IC568_RS21220	COG4568	rho-dependent transcription termination
IC568_RS21230	COG0346	lactoylglutathione lyase activity
IC568_RS21235	COG1982	Orn Lys Arg decarboxylase major
IC568_RS21275	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IC568_RS21285	COG0750	zinc metalloprotease
IC568_RS21290	COG0575	Belongs to the CDS family
IC568_RS21300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IC568_RS21325	COG0024	Methionine aminopeptidase
IC568_RS21330	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IC568_RS21345	COG3835	regulator
IC568_RS21350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC568_RS21370	COG2860	membrane
IC568_RS21390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC568_RS21395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IC568_RS21400	COG1120	ATPase activity
IC568_RS21405	COG4774	siderophore transport
IC568_RS21410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC568_RS21510	COG1643	Atp-dependent helicase
IC568_RS21515	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IC568_RS21535	COG0617	tRNA 3'-terminal CCA addition
IC568_RS21540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC568_RS21560	COG0726	polysaccharide deacetylase
IC568_RS21565	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS21570	COG0842	Transport permease protein
IC568_RS21575	COG1131	(ABC) transporter
IC568_RS21580	COG0288	reversible hydration of carbon dioxide
IC568_RS21595	COG4993	Dehydrogenase
IC568_RS21600	COG2132	Multicopper oxidase
IC568_RS21640	COG3064	Membrane
IC568_RS21655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC568_RS21660	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC568_RS21665	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IC568_RS21670	COG2186	Transcriptional regulator
IC568_RS21675	COG1113	amino acid transport
IC568_RS21680	COG2211	Major facilitator Superfamily
IC568_RS21685	COG3940	Belongs to the glycosyl hydrolase 43 family
IC568_RS21690	COG3725	Membrane protein required for beta-lactamase induction
IC568_RS21695	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC568_RS21705	COG4969	Belongs to the N-Me-Phe pilin family
IC568_RS21710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC568_RS21715	COG1459	type II secretion system
IC568_RS21740	COG0494	nUDIX hydrolase
IC568_RS21760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC568_RS21765	COG0849	cell division
IC568_RS21790	COG0772	Belongs to the SEDS family
IC568_RS21805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC568_RS21810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC568_RS21815	COG0768	penicillin binding
IC568_RS21835	COG1609	Transcriptional regulator
IC568_RS21845	COG0028	Belongs to the TPP enzyme family
IC568_RS21890	COG0738	Major facilitator superfamily
IC568_RS21900	COG0583	DNA-binding transcription factor activity
IC568_RS21905	COG2271	Major facilitator Superfamily
IC568_RS21910	COG2814	Major facilitator Superfamily
IC568_RS21930	COG1178	ABC-type Fe3 transport system permease component
IC568_RS21940	COG0586	Pfam SNARE associated Golgi protein
IC568_RS21960	COG0235	Class ii aldolase
IC568_RS21965	COG0417	DNA replication proofreading
IC568_RS21975	COG0564	pseudouridine synthase activity
IC568_RS21985	COG3493	citrate carrier protein
IC568_RS22000	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IC568_RS22005	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IC568_RS22015	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC568_RS22060	COG0505	Belongs to the CarA family
IC568_RS22070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IC568_RS22095	COG1047	Peptidyl-prolyl cis-trans
IC568_RS22110	COG0196	riboflavin kinase activity
IC568_RS22120	COG0583	DNA-binding transcription factor activity
IC568_RS22145	COG4735	regulation of single-species biofilm formation
IC568_RS22150	COG1584	GPR1 FUN34 yaaH family protein
IC568_RS22155	COG0477	Major facilitator Superfamily
IC568_RS22160	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC568_RS22165	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC568_RS22170	COG1115	amino acid carrier protein
IC568_RS22185	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC568_RS22195	COG0460	homoserine dehydrogenase
IC568_RS22195	COG0527	aspartate kinase activity
IC568_RS22205	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IC568_RS22215	COG0745	RESPONSE REGULATOR receiver
IC568_RS22220	COG4452	Inner membrane protein CreD
IC568_RS22225	COG2205	protein histidine kinase activity
IC568_RS22230	COG0745	RESPONSE REGULATOR receiver
IC568_RS22235	COG3045	CreA protein
IC568_RS22240	COG3708	Transcriptional regulator
IC568_RS22240	COG2207	Transcriptional regulator
IC568_RS22260	COG0741	lytic transglycosylase activity
IC568_RS22265	COG0488	(ABC) transporter
IC568_RS22275	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IC568_RS22280	COG0560	Phosphoserine phosphatase
IC568_RS22285	COG3726	membrane protein affecting hemolysin expression
IC568_RS22315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IC568_RS22320	COG0084	hydrolase, TatD family'
IC568_RS22325	COG4667	esterase of the alpha-beta hydrolase superfamily
IC568_RS22335	COG2823	Periplasmic or secreted lipoprotein
IC568_RS22345	COG1011	Hydrolase
IC568_RS22350	COG0456	acetyltransferase
IC568_RS22355	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
IC568_RS22390	COG3706	GGDEF domain
IC568_RS22395	COG4114	ferric iron reductase
IC568_RS22400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC568_RS22400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC568_RS22405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC568_RS22410	COG2197	response regulator
IC568_RS22415	COG2197	response regulator
IC568_RS22430	COG2966	Psort location CytoplasmicMembrane, score
IC568_RS22445	COG1484	DNA-dependent DNA replication
IC568_RS22460	COG5464	transposase or invertase
IC568_RS22470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC568_RS22475	COG3716	PTS system mannose fructose sorbose family IID component
IC568_RS22480	COG3715	PTS system
IC568_RS22495	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IC568_RS22495	COG3933	PFAM sigma-54 factor interaction domain-containing protein
IC568_RS22500	COG0456	acetyltransferase
IC568_RS22500	COG1214	PFAM Peptidase M22, glycoprotease
IC568_RS22510	COG1737	Transcriptional regulator
IC568_RS22515	COG0800	Aldolase
IC568_RS22520	COG3734	2-keto-3-deoxy-galactonokinase
IC568_RS22535	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IC568_RS22565	COG1846	Transcriptional regulator
IC568_RS22575	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC568_RS22585	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS22590	COG3384	dioxygenase
IC568_RS22600	COG3971	2-oxopent-4-enoate hydratase activity
IC568_RS22620	COG2368	4-hydroxyphenylacetate
IC568_RS22625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC568_RS22640	COG1966	Carbon starvation protein
IC568_RS22645	COG2879	small protein
IC568_RS22650	COG0523	cobalamin synthesis protein
IC568_RS22660	COG1012	belongs to the aldehyde dehydrogenase family
IC568_RS22665	COG5464	transposase or invertase
IC568_RS22670	COG1917	Cupin 2, conserved barrel domain protein
IC568_RS22670	COG2207	Transcriptional regulator
IC568_RS22680	COG2733	membrane
IC568_RS22695	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
IC568_RS22700	COG1924	4 iron, 4 sulfur cluster binding
IC568_RS22715	COG1566	PFAM secretion protein HlyD family protein
IC568_RS22725	COG5457	Domain of unknown function (DUF1127)
IC568_RS22730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC568_RS22745	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC568_RS22755	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS22760	COG1129	ABC transporter
IC568_RS22765	COG1879	ABC-type sugar transport system periplasmic component
IC568_RS22775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC568_RS22780	COG1129	ABC transporter
IC568_RS22780	COG0842	Transport permease protein
IC568_RS22785	COG0842	Transport permease protein
IC568_RS22815	COG2850	peptidyl-arginine hydroxylation
IC568_RS22830	COG5002	protein histidine kinase activity
IC568_RS22835	COG0745	RESPONSE REGULATOR receiver
IC568_RS22840	COG1538	Outer membrane efflux protein
IC568_RS22845	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC568_RS22850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC568_RS22855	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC568_RS22865	COG3040	lipid binding
IC568_RS22870	COG0789	Transcriptional regulator
IC568_RS22880	COG0300	oxidoreductase activity
IC568_RS22895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC568_RS22915	COG3272	Protein of unknown function (DUF1722)
IC568_RS22920	COG4580	involved in the transport of maltose and maltodextrins
IC568_RS22925	COG2115	Belongs to the xylose isomerase family
IC568_RS22930	COG2211	Major facilitator Superfamily
IC568_RS22935	COG3507	Belongs to the glycosyl hydrolase 43 family
IC568_RS22945	COG0584	glycerophosphoryl diester phosphodiesterase
IC568_RS22955	COG1176	ABC-type spermidine putrescine transport system, permease component I
IC568_RS23070	COG1401	restriction endodeoxyribonuclease activity
IC568_RS23130	COG2815	serine threonine protein kinase
IC568_RS23130	COG0515	serine threonine protein kinase
IC568_RS23135	COG0582	viral genome integration into host DNA
IC568_RS23145	COG0288	reversible hydration of carbon dioxide
IC568_RS23150	COG0659	secondary active sulfate transmembrane transporter activity
IC568_RS23155	COG1064	alcohol dehydrogenase
IC568_RS23160	COG1175	transmembrane transport
IC568_RS23165	COG0395	ABC-type sugar transport system, permease component
IC568_RS23170	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IC568_RS23175	COG3842	ATPase activity
IC568_RS23180	COG1653	transport
IC568_RS23190	COG1082	Xylose isomerase domain protein TIM barrel
IC568_RS23200	COG3962	Belongs to the TPP enzyme family
IC568_RS23205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC568_RS23210	COG1737	Transcriptional regulator
IC568_RS23210	COG0837	glucose binding
IC568_RS23215	COG3718	enzyme involved in inositol metabolism
IC568_RS23230	COG0433	COG0433 Predicted ATPase
IC568_RS23235	COG0795	lipopolysaccharide-transporting ATPase activity
IC568_RS23240	COG0795	lipopolysaccharide-transporting ATPase activity
IC568_RS23250	COG2927	DNA polymerase III (CHI subunit)
IC568_RS23255	COG0525	valine-tRNA ligase activity
IC568_RS23280	COG2188	Transcriptional regulator
IC568_RS23285	COG1288	antiporter activity
IC568_RS23290	COG1228	amidohydrolase
IC568_RS23295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC568_RS23300	COG2222	sugar isomerase
IC568_RS23305	COG2731	YhcH YjgK YiaL family protein
IC568_RS23340	COG1263	PTS System
IC568_RS23340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC568_RS23345	COG0366	Alpha amylase catalytic
IC568_RS23350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC568_RS23355	COG1486	melibiose metabolic process
IC568_RS23380	COG0602	queuosine metabolic process
IC568_RS23385	COG2026	Addiction module toxin, RelE StbE family
IC568_RS23390	COG3077	Addiction module antitoxin, RelB DinJ family
IC568_RS23395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC568_RS23395	COG3711	transcriptional antiterminator
IC568_RS23400	COG2706	6-phosphogluconolactonase activity
IC568_RS23415	COG3964	amidohydrolase
IC568_RS23450	COG0312	modulator of DNA gyrase
IC568_RS23475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC568_RS23485	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS23490	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS23495	COG1129	ABC transporter
IC568_RS23500	COG1879	ABC-type sugar transport system periplasmic component
IC568_RS23515	COG2105	PFAM AIG2 family protein
IC568_RS23520	COG2911	Protein conserved in bacteria
IC568_RS23525	COG0729	surface antigen
IC568_RS23535	COG1253	flavin adenine dinucleotide binding
IC568_RS23560	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IC568_RS23575	COG1733	regulation of RNA biosynthetic process
IC568_RS23580	COG0702	epimerase
IC568_RS23590	COG0697	spore germination
IC568_RS23600	COG1113	amino acid transport
IC568_RS23605	COG0545	Peptidyl-prolyl cis-trans isomerase
IC568_RS23610	COG3061	Opacity-associated protein A
IC568_RS23620	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IC568_RS23625	COG2965	DNA replication, synthesis of RNA primer
IC568_RS23685	COG1073	alpha beta
IC568_RS23690	COG3650	response to hydrogen peroxide
IC568_RS23700	COG1960	acyl-CoA dehydrogenase activity
IC568_RS23705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC568_RS23710	COG0557	exoribonuclease II activity
IC568_RS23725	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IC568_RS23735	COG0330	HflC and HflK could
IC568_RS23740	COG0330	HflC and HflK could
IC568_RS23745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC568_RS23765	COG0860	N-Acetylmuramoyl-L-alanine amidase
IC568_RS23770	COG0802	atpase or kinase
IC568_RS23775	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC568_RS23775	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC568_RS23780	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC568_RS23800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC568_RS23820	COG3264	Mechanosensitive ion channel
IC568_RS23820	COG1511	domain protein
IC568_RS23835	COG1053	succinate dehydrogenase
IC568_RS23840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC568_RS23860	COG2076	Multidrug Resistance protein
IC568_RS23865	COG5510	response to toxic substance
IC568_RS23880	COG1509	lysine 2,3-aminomutase activity
IC568_RS23945	COG0531	amino acid
IC568_RS23950	COG3030	protein affecting phage T7 exclusion by the F plasmid
IC568_RS23955	COG1027	Aspartate ammonia-lyase
IC568_RS23960	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IC568_RS23975	COG1309	transcriptional regulator
IC568_RS24010	COG0457	Tetratricopeptide repeat
IC568_RS24015	COG1649	PFAM Uncharacterised BCR, COG1649
IC568_RS24015	COG0726	polysaccharide deacetylase
IC568_RS24020	COG1215	transferase activity, transferring glycosyl groups
IC568_RS24035	COG0861	Integral membrane protein TerC family
IC568_RS24075	COG1486	melibiose metabolic process
IC568_RS24080	COG2169	Transcriptional regulator
IC568_RS24090	COG2824	Alkylphosphonate utilization operon protein PhnA
IC568_RS24095	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IC568_RS24100	COG2188	Transcriptional regulator
IC568_RS24105	COG3624	Phosphonate C-P lyase system protein PhnG
IC568_RS24110	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IC568_RS24115	COG3626	phosphonate metabolism
IC568_RS24120	COG3627	carbon phosphorus lyase activity
IC568_RS24125	COG4107	phosphonate C-P lyase system protein PhnK
IC568_RS24130	COG4778	phosphonate C-P lyase system protein PhnL
IC568_RS24135	COG3454	Phosphonate metabolism
IC568_RS24145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IC568_RS24155	COG0784	Response regulator, receiver
IC568_RS24155	COG4191	Histidine kinase
IC568_RS24160	COG1129	ABC transporter
IC568_RS24165	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS24200	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IC568_RS24205	COG1301	dicarboxylic acid transport
IC568_RS24215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC568_RS24220	COG3162	membrane
IC568_RS24250	COG3539	Fimbrial protein
IC568_RS24255	COG1346	cytolysis
IC568_RS24260	COG1380	Effector of murein hydrolase LrgA
IC568_RS24265	COG0583	DNA-binding transcription factor activity
IC568_RS24270	COG0025	NhaP-type Na H and K H
IC568_RS24275	COG2252	PERMEase
IC568_RS24280	COG0625	glutathione transferase activity
IC568_RS24285	COG0789	Transcriptional regulator
IC568_RS24295	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC568_RS24325	COG1234	tRNA 3'-trailer cleavage
IC568_RS24330	COG1609	Transcriptional regulator
IC568_RS24335	COG0483	inositol monophosphate 1-phosphatase activity
IC568_RS24345	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC568_RS24365	COG4771	TonB-dependent receptor
IC568_RS24370	COG0741	lytic transglycosylase activity
IC568_RS24385	COG2315	Protein conserved in bacteria
IC568_RS24390	COG0432	Pfam Uncharacterised protein family UPF0047
IC568_RS24405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC568_RS24410	COG0305	Participates in initiation and elongation during chromosome replication
IC568_RS24425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC568_RS24435	COG0735	belongs to the Fur family
IC568_RS24440	COG3237	CsbD-like
IC568_RS24450	COG0534	Mate efflux family protein
IC568_RS24460	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IC568_RS24530	COG0251	oxidation-reduction process
IC568_RS24540	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IC568_RS24550	COG0527	aspartate kinase activity
IC568_RS24605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IC568_RS24635	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC568_RS24645	COG0456	acetyltransferase
IC568_RS24675	COG0151	Belongs to the GarS family
IC568_RS24685	COG4191	Histidine kinase
IC568_RS24690	COG3678	ATP-independent chaperone mediated protein folding
IC568_RS24725	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
IC568_RS24740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IC568_RS24745	COG2104	thiamine diphosphate biosynthetic process
IC568_RS24760	COG3706	GGDEF domain
IC568_RS24770	COG1447	Phosphotransferase system cellobiose-specific component IIA
IC568_RS24775	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IC568_RS24810	COG0250	Participates in transcription elongation, termination and antitermination
IC568_RS24855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IC568_RS24885	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IC568_RS24895	COG1739	Uncharacterized protein family UPF0029
IC568_RS24935	COG0805	protein transport
IC568_RS24955	COG3165	ubiquinone biosynthetic process from chorismate
IC568_RS24985	COG0583	DNA-binding transcription factor activity
IC568_RS24990	COG0697	spore germination
IC568_RS24995	COG0561	phosphatase activity
IC568_RS25000	COG2267	carboxylic ester hydrolase activity
IC568_RS25005	COG1280	lysine exporter protein (LysE YggA)
IC568_RS25015	COG1280	lysine exporter protein (LysE YggA)
IC568_RS25045	COG0210	DNA helicase
IC568_RS25050	COG1011	Hydrolase
IC568_RS25080	COG3072	Adenylate cyclase
IC568_RS25095	COG2959	enzyme of heme biosynthesis
IC568_RS25100	COG3071	HemY protein
IC568_RS25145	COG2244	polysaccharide biosynthetic process
IC568_RS25150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IC568_RS25155	COG0456	acetyltransferase
IC568_RS25160	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC568_RS25165	COG1088	dTDP-glucose 4,6-dehydratase activity
IC568_RS25170	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IC568_RS25175	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC568_RS25185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IC568_RS25190	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IC568_RS25195	COG3118	belongs to the thioredoxin family
IC568_RS25220	COG1811	Na channel or pump
IC568_RS25230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC568_RS25235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC568_RS25245	COG0583	DNA-binding transcription factor activity
IC568_RS25250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC568_RS25265	COG3978	acetolactate synthase activity
IC568_RS25285	COG3085	chromosome segregation
IC568_RS25360	COG0583	DNA-binding transcription factor activity
IC568_RS25375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IC568_RS25390	COG3443	Belongs to the bacterial solute-binding protein 9 family
IC568_RS25395	COG2207	Transcriptional regulator
IC568_RS25405	COG0371	Dehydrogenase
IC568_RS25410	COG0697	spore germination
IC568_RS25420	COG0583	DNA-binding transcription factor activity
IC568_RS25430	COG0737	Belongs to the 5'-nucleotidase family
IC568_RS25440	COG0527	aspartate kinase activity
IC568_RS25440	COG0460	homoserine dehydrogenase
IC568_RS25445	COG0626	cystathionine gamma-synthase activity
IC568_RS25460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC568_RS25465	COG1609	Transcriptional regulator
IC568_RS25470	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IC568_RS25485	COG1575	Belongs to the MenA family. Type 1 subfamily
IC568_RS25505	COG3678	ATP-independent chaperone mediated protein folding
IC568_RS25510	COG0745	RESPONSE REGULATOR receiver
IC568_RS25515	COG2205	protein histidine kinase activity
IC568_RS25520	COG2258	MOSC domain
IC568_RS25525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC568_RS25565	COG1129	ABC transporter
IC568_RS25570	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS25575	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS25580	COG1454	alcohol dehydrogenase
IC568_RS25590	COG2211	Major facilitator Superfamily
IC568_RS25650	COG0205	6-phosphofructokinase activity
IC568_RS25670	COG0437	4 iron, 4 sulfur cluster binding
IC568_RS25675	COG2864	formate dehydrogenase
IC568_RS25690	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC568_RS25700	COG0456	acetyltransferase
IC568_RS25715	COG1011	Hydrolase
IC568_RS25730	COG3852	Histidine kinase
IC568_RS25745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC568_RS25765	COG0204	Acyl-transferase
IC568_RS25775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC568_RS25780	COG3084	Protein conserved in bacteria
IC568_RS25790	COG1763	Mo-molybdopterin cofactor biosynthetic process
IC568_RS25815	COG2186	Transcriptional regulator
IC568_RS25820	COG0477	Major facilitator Superfamily
IC568_RS25825	COG1609	Transcriptional regulator
IC568_RS25830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC568_RS25840	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC568_RS25845	COG1129	ABC transporter
IC568_RS25875	COG1522	sequence-specific DNA binding
IC568_RS25880	COG0716	FMN binding
IC568_RS25895	COG3312	ion transport
IC568_RS25945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC568_RS25950	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC568_RS25955	COG0573	inorganic phosphate transmembrane transporter activity
IC568_RS25960	COG0581	inorganic phosphate transmembrane transporter activity
IC568_RS25965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC568_RS25970	COG0704	Plays a role in the regulation of phosphate uptake
IC568_RS25980	COG2382	esterase
IC568_RS25985	COG0363	glucosamine-6-phosphate deaminase activity
IC568_RS25990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC568_RS25995	COG2252	PERMEase
IC568_RS26000	COG0431	NADPH-dependent FMN reductase
IC568_RS26005	COG2091	lysine biosynthetic process via aminoadipic acid
IC568_RS26035	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IC568_RS26060	COG2203	Gaf domain
IC568_RS26060	COG2199	diguanylate cyclase activity
IC568_RS26065	COG5001	Diguanylate cyclase
IC568_RS26065	COG1716	ATPase activity
IC568_RS26080	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC568_RS26090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC568_RS26145	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC568_RS26175	COG0739	heme binding
IC568_RS26185	COG2132	Multicopper oxidase
IC568_RS26190	COG3667	copper resistance
IC568_RS26195	COG2372	response to copper ion
IC568_RS26200	COG1276	copper resistance
IC568_RS26205	COG0745	RESPONSE REGULATOR receiver
IC568_RS26210	COG2205	protein histidine kinase activity
IC568_RS26265	COG1620	l-lactate permease
IC568_RS26270	COG0277	FAD linked oxidase domain protein
IC568_RS26275	COG0247	lactate metabolic process
IC568_RS26280	COG1139	Iron-sulfur cluster binding protein
IC568_RS26285	COG1556	Lactate utilization protein
IC568_RS26295	COG4680	protein conserved in bacteria
IC568_RS26340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IC568_RS26370	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IC568_RS26375	COG1028	Short-chain dehydrogenase reductase Sdr
IC568_RS26380	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC568_RS26385	COG1902	pentaerythritol trinitrate reductase activity
IC568_RS26390	COG3118	belongs to the thioredoxin family
IC568_RS26395	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC568_RS26435	COG3436	PFAM IS66 Orf2 family protein
IC568_RS26440	COG1120	ATPase activity
IC568_RS26445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC568_RS26450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC568_RS26455	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IC568_RS26460	COG4772	TonB-dependent receptor
IC568_RS26465	COG3712	iron ion homeostasis
IC568_RS26470	COG1595	DNA-templated transcription, initiation
IC568_RS26495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC568_RS26500	COG0601	transmembrane transport
IC568_RS26515	COG4172	Belongs to the ABC transporter superfamily
IC568_RS26570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IC568_RS26655	COG1192	Involved in chromosome partitioning
IC568_RS26700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC568_RS26765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC568_RS26870	COG0616	signal peptide processing
IC568_RS26950	COG0673	inositol 2-dehydrogenase activity
IC568_RS26995	COG1660	Displays ATPase and GTPase activities
IC568_RS27020	COG0768	penicillin binding
IC568_RS27125	COG0697	spore germination
IC568_RS27210	COG2003	Belongs to the UPF0758 family
IC568_RS27270	COG1695	Transcriptional regulator
IC568_RS27290	COG3173	Aminoglycoside phosphotransferase
IC568_RS27305	COG3300	MHYT domain
IC568_RS27305	COG5001	Diguanylate cyclase
IC568_RS27375	COG1660	Displays ATPase and GTPase activities
IC568_RS27420	COG2223	nitrite transmembrane transporter activity
IC568_RS27430	COG1609	Transcriptional regulator
IC568_RS27440	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
IC568_RS27650	COG2801	Transposase and inactivated derivatives
IC568_RS27660	COG2801	Transposase and inactivated derivatives
IC568_RS27710	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC568_RS27715	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IC568_RS27745	COG2986	histidine ammonia-lyase
IC568_RS27755	COG2188	Transcriptional regulator
IC568_RS27760	COG0402	S-adenosylhomocysteine deaminase activity
IC568_RS27785	COG5499	transcription regulator containing HTH domain
IC568_RS27790	COG4680	protein conserved in bacteria
IC568_RS27805	COG3436	PFAM IS66 Orf2 family protein
IC568_RS27810	COG4372	Transposase
IC568_RS27820	COG3039	Transposase
IC568_RS27830	COG4598	ABC transporter
IC568_RS27835	COG0765	amino acid transport
IC568_RS27840	COG0765	amino acid transport
IC568_RS27850	COG0583	DNA-binding transcription factor activity
IC568_RS27880	COG5654	RES domain protein
IC568_RS27885	COG5642	Protein of unknown function (DUF2384)
IC568_RS27915	COG3436	PFAM IS66 Orf2 family protein
IC568_RS27935	COG0501	Belongs to the peptidase M48B family
IC568_RS27945	COG3706	GGDEF domain
IC568_RS27955	COG0542	response to heat
IC568_RS27960	COG0071	Belongs to the small heat shock protein (HSP20) family
IC568_RS27990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC568_RS28025	COG0683	leucine binding
IC568_RS28030	COG0784	Response regulator, receiver
IC568_RS28030	COG2198	Histidine kinase
IC568_RS28030	COG5002	protein histidine kinase activity
IC568_RS28035	COG0745	RESPONSE REGULATOR receiver
IC568_RS28110	COG3344	reverse transcriptase
IC568_RS28210	COG0577	efflux transmembrane transporter activity
IC568_RS28210	COG1136	(ABC) transporter
IC568_RS28220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC568_RS28235	COG4372	Transposase
IC568_RS28240	COG3436	PFAM IS66 Orf2 family protein