locus-tag	class	description
GJJ12_RS00020	COG0187	DNA topoisomerase II activity
GJJ12_RS00025	COG0561	phosphatase activity
GJJ12_RS00040	COG2186	Transcriptional regulator
GJJ12_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
GJJ12_RS00050	COG0800	Aldolase
GJJ12_RS00060	COG2271	Major facilitator Superfamily
GJJ12_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
GJJ12_RS00070	COG5645	(Lipo)protein
GJJ12_RS00085	COG3645	SOS response
GJJ12_RS00095	COG2188	Transcriptional regulator
GJJ12_RS00110	COG2149	membrane
GJJ12_RS00130	COG2610	gluconate transmembrane transporter activity
GJJ12_RS00140	COG0583	DNA-binding transcription factor activity
GJJ12_RS00145	COG2814	Major facilitator Superfamily
GJJ12_RS00175	COG0028	Belongs to the TPP enzyme family
GJJ12_RS00180	COG0440	acetolactate synthase activity
GJJ12_RS00185	COG2197	response regulator
GJJ12_RS00195	COG2271	Major facilitator Superfamily
GJJ12_RS00235	COG2188	Transcriptional regulator
GJJ12_RS00265	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJJ12_RS00270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJJ12_RS00270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJJ12_RS00280	COG1609	Transcriptional regulator
GJJ12_RS00290	COG3384	dioxygenase
GJJ12_RS00295	COG0583	DNA-binding transcription factor activity
GJJ12_RS00300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GJJ12_RS00305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GJJ12_RS00310	COG2828	Protein conserved in bacteria
GJJ12_RS00325	COG0697	spore germination
GJJ12_RS00330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJJ12_RS00330	COG1263	PTS System
GJJ12_RS00340	COG2814	Major facilitator Superfamily
GJJ12_RS00350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GJJ12_RS00385	COG0583	DNA-binding transcription factor activity
GJJ12_RS00410	COG1464	Belongs to the NlpA lipoprotein family
GJJ12_RS00425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GJJ12_RS00435	COG1064	alcohol dehydrogenase
GJJ12_RS00465	COG2211	Major facilitator Superfamily
GJJ12_RS00495	COG1486	melibiose metabolic process
GJJ12_RS00500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJJ12_RS00500	COG1263	PTS System
GJJ12_RS00505	COG2982	Protein involved in outer membrane biogenesis
GJJ12_RS00510	COG2233	PERMEase
GJJ12_RS00515	COG0786	glutamate:sodium symporter activity
GJJ12_RS00535	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GJJ12_RS00560	COG3152	Membrane
GJJ12_RS00570	COG1494	fructose-1,6-bisphosphatase
GJJ12_RS00575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GJJ12_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJJ12_RS00585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GJJ12_RS00605	COG2860	membrane
GJJ12_RS00615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GJJ12_RS00615	COG2169	Transcriptional regulator
GJJ12_RS00620	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GJJ12_RS00625	COG1561	YicC-like family, N-terminal region
GJJ12_RS00645	COG1131	(ABC) transporter
GJJ12_RS00650	COG0842	Transport permease protein
GJJ12_RS00680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GJJ12_RS00715	COG1519	Transferase
GJJ12_RS00720	COG1216	Glycosyl transferase, family 2
GJJ12_RS00725	COG0438	transferase activity, transferring glycosyl groups
GJJ12_RS00735	COG0859	PFAM glycosyl transferase family 9
GJJ12_RS00760	COG0859	PFAM glycosyl transferase family 9
GJJ12_RS00775	COG0156	8-amino-7-oxononanoate synthase activity
GJJ12_RS00785	COG0463	Glycosyl transferase, family 2
GJJ12_RS00790	COG2861	carbohydrate metabolic process
GJJ12_RS00795	COG4942	peptidase
GJJ12_RS00805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GJJ12_RS00810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GJJ12_RS00830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GJJ12_RS00840	COG2186	Transcriptional regulator
GJJ12_RS00860	COG3722	fumarate hydratase activity
GJJ12_RS00880	COG1566	PFAM secretion protein HlyD family protein
GJJ12_RS00885	COG0625	glutathione transferase activity
GJJ12_RS00895	COG3276	selenocysteine insertion sequence binding
GJJ12_RS00900	COG1414	Transcriptional regulator
GJJ12_RS00905	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GJJ12_RS00910	COG3977	Valine--pyruvate aminotransferase
GJJ12_RS00915	COG0366	Alpha amylase catalytic
GJJ12_RS00920	COG2992	FlgJ-related protein
GJJ12_RS00925	COG2207	Transcriptional regulator
GJJ12_RS00925	COG1609	Transcriptional regulator
GJJ12_RS00930	COG4214	carbohydrate transport
GJJ12_RS00940	COG4213	ABC transporter substrate-binding protein
GJJ12_RS00955	COG4682	membrane
GJJ12_RS00960	COG4682	membrane
GJJ12_RS00965	COG3274	enterobacterial common antigen metabolic process
GJJ12_RS01000	COG1278	Cold shock
GJJ12_RS01005	COG2944	sequence-specific DNA binding
GJJ12_RS01010	COG2814	Major facilitator Superfamily
GJJ12_RS01030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GJJ12_RS01040	COG1609	Transcriptional regulator
GJJ12_RS01045	COG2885	chlorophyll binding
GJJ12_RS01050	COG0243	molybdopterin cofactor binding
GJJ12_RS01055	COG0456	acetyltransferase
GJJ12_RS01060	COG2818	Glycosylase
GJJ12_RS01065	COG5571	outer membrane autotransporter
GJJ12_RS01070	COG2223	nitrite transmembrane transporter activity
GJJ12_RS01095	COG0747	negative chemotaxis
GJJ12_RS01100	COG0601	transmembrane transport
GJJ12_RS01105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJJ12_RS01110	COG0444	Belongs to the ABC transporter superfamily
GJJ12_RS01115	COG4608	Belongs to the ABC transporter superfamily
GJJ12_RS01140	COG1215	transferase activity, transferring glycosyl groups
GJJ12_RS01145	COG0457	Tetratricopeptide repeat
GJJ12_RS01160	COG2194	sulfuric ester hydrolase activity
GJJ12_RS01190	COG1215	transferase activity, transferring glycosyl groups
GJJ12_RS01195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GJJ12_RS01200	COG0457	Tetratricopeptide repeat
GJJ12_RS01200	COG3118	belongs to the thioredoxin family
GJJ12_RS01205	COG2199	diguanylate cyclase activity
GJJ12_RS01205	COG2200	EAL domain
GJJ12_RS01215	COG0612	Peptidase, M16
GJJ12_RS01225	COG2982	Protein involved in outer membrane biogenesis
GJJ12_RS01230	COG0477	Major facilitator Superfamily
GJJ12_RS01235	COG1295	ribonuclease BN
GJJ12_RS01240	COG0583	DNA-binding transcription factor activity
GJJ12_RS01245	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS01250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GJJ12_RS01260	COG1454	alcohol dehydrogenase
GJJ12_RS01270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJJ12_RS01275	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GJJ12_RS01280	COG0671	phosphoesterase, PA-phosphatase related
GJJ12_RS01300	COG0589	response to stress
GJJ12_RS01310	COG0306	phosphate transporter
GJJ12_RS01315	COG2081	HI0933 family
GJJ12_RS01320	COG2239	Acts as a magnesium transporter
GJJ12_RS01330	COG1124	(ABC) transporter
GJJ12_RS01340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJJ12_RS01345	COG0601	transmembrane transport
GJJ12_RS01350	COG0747	negative chemotaxis
GJJ12_RS01360	COG3479	Phenolic acid decarboxylase
GJJ12_RS01400	COG0628	permease
GJJ12_RS01405	COG0477	Major facilitator Superfamily
GJJ12_RS01415	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GJJ12_RS01430	COG3714	YhhN family
GJJ12_RS01440	COG3776	membrane
GJJ12_RS01445	COG0742	ribosomal rna small subunit methyltransferase
GJJ12_RS01450	COG0552	protein localization to endoplasmic reticulum
GJJ12_RS01455	COG2884	Cell division ATP-binding protein ftsE
GJJ12_RS01460	COG2177	Part of the ABC transporter FtsEX involved in
GJJ12_RS01475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GJJ12_RS01490	COG0683	leucine binding
GJJ12_RS01500	COG0683	leucine binding
GJJ12_RS01505	COG0559	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS01555	COG0584	glycerophosphoryl diester phosphodiesterase
GJJ12_RS01565	COG0405	Gamma-glutamyltransferase
GJJ12_RS01570	COG1247	-acetyltransferase
GJJ12_RS01580	COG0673	inositol 2-dehydrogenase activity
GJJ12_RS01585	COG1741	Belongs to the pirin family
GJJ12_RS01590	COG1609	Transcriptional regulator
GJJ12_RS01595	COG3265	gluconokinase activity
GJJ12_RS01600	COG2610	gluconate transmembrane transporter activity
GJJ12_RS01610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GJJ12_RS01635	COG0058	SHG alpha-glucan phosphorylase activity
GJJ12_RS01650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GJJ12_RS01665	COG1349	DNA-binding transcription factor activity
GJJ12_RS01675	COG0058	SHG alpha-glucan phosphorylase activity
GJJ12_RS01680	COG1640	4-alpha-glucanotransferase
GJJ12_RS01685	COG2610	gluconate transmembrane transporter activity
GJJ12_RS01695	COG1040	competence protein
GJJ12_RS01720	COG1918	ferrous iron import across plasma membrane
GJJ12_RS01725	COG2183	response to ionizing radiation
GJJ12_RS01730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GJJ12_RS01755	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GJJ12_RS01760	COG1011	Hydrolase
GJJ12_RS01770	COG0494	nUDIX hydrolase
GJJ12_RS01775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GJJ12_RS01800	COG4796	Type ii and iii secretion system protein
GJJ12_RS01815	COG3266	domain, Protein
GJJ12_RS01820	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GJJ12_RS01825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GJJ12_RS01850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GJJ12_RS01855	COG0402	S-adenosylhomocysteine deaminase activity
GJJ12_RS01860	COG0738	Major facilitator superfamily
GJJ12_RS01885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GJJ12_RS01890	COG1289	transmembrane transporter activity
GJJ12_RS01900	COG1765	OsmC-like protein
GJJ12_RS01905	COG3954	Phosphoribulokinase
GJJ12_RS01915	COG0429	hydrolase of the alpha beta-hydrolase fold
GJJ12_RS01920	COG0488	(ABC) transporter
GJJ12_RS01935	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GJJ12_RS01940	COG1047	Peptidyl-prolyl cis-trans
GJJ12_RS01950	COG0545	Peptidyl-prolyl cis-trans isomerase
GJJ12_RS01955	COG2964	Protein conserved in bacteria
GJJ12_RS02010	COG0051	transcription antitermination factor activity, RNA binding
GJJ12_RS02035	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GJJ12_RS02050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GJJ12_RS02115	COG0201	protein transport
GJJ12_RS02140	COG0202	RNA polymerase activity
GJJ12_RS02155	COG0789	Transcriptional regulator
GJJ12_RS02160	COG3036	rescue of stalled ribosome
GJJ12_RS02190	COG0758	DNA mediated transformation
GJJ12_RS02200	COG0551	DNA topoisomerase type I activity
GJJ12_RS02220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GJJ12_RS02255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GJJ12_RS02260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJJ12_RS02265	COG1309	transcriptional regulator
GJJ12_RS02285	COG4145	pantothenate transmembrane transporter activity
GJJ12_RS02290	COG3924	membrane
GJJ12_RS02295	COG0439	Biotin carboxylase
GJJ12_RS02300	COG0511	ligase activity, forming carbon-carbon bonds
GJJ12_RS02325	COG2200	EAL domain
GJJ12_RS02325	COG2199	diguanylate cyclase activity
GJJ12_RS02330	COG1077	Cell shape determining protein MreB Mrl
GJJ12_RS02335	COG1792	Involved in formation and maintenance of cell shape
GJJ12_RS02340	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GJJ12_RS02350	COG1530	ribonuclease E activity
GJJ12_RS02355	COG3164	Protein of unknown function
GJJ12_RS02360	COG0312	modulator of DNA gyrase
GJJ12_RS02365	COG0583	DNA-binding transcription factor activity
GJJ12_RS02380	COG1289	transmembrane transporter activity
GJJ12_RS02385	COG2732	(Barnase) inhibitor
GJJ12_RS02420	COG0471	metal ion transport
GJJ12_RS02425	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GJJ12_RS02430	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GJJ12_RS02455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GJJ12_RS02460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GJJ12_RS02465	COG3105	Protein conserved in bacteria
GJJ12_RS02470	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GJJ12_RS02485	COG0625	glutathione transferase activity
GJJ12_RS02490	COG2969	positive regulation of protein catabolic process
GJJ12_RS02500	COG0493	'glutamate synthase
GJJ12_RS02505	COG0070	glutamate synthase
GJJ12_RS02505	COG0069	glutamate synthase activity
GJJ12_RS02505	COG0067	glutamate synthase
GJJ12_RS02510	COG1242	4 iron, 4 sulfur cluster binding
GJJ12_RS02515	COG2271	Major facilitator Superfamily
GJJ12_RS02520	COG1063	alcohol dehydrogenase
GJJ12_RS02525	COG1312	Catalyzes the dehydration of D-mannonate
GJJ12_RS02530	COG2198	Histidine kinase
GJJ12_RS02530	COG0784	Response regulator, receiver
GJJ12_RS02530	COG5002	protein histidine kinase activity
GJJ12_RS02535	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GJJ12_RS02540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJJ12_RS02545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJJ12_RS02555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJJ12_RS02560	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GJJ12_RS02565	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GJJ12_RS02570	COG1137	ATPase activity
GJJ12_RS02575	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GJJ12_RS02580	COG3117	lipopolysaccharide transmembrane transporter activity
GJJ12_RS02585	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GJJ12_RS02595	COG0530	calcium, potassium:sodium antiporter activity
GJJ12_RS02600	COG1127	ABC transporter
GJJ12_RS02605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GJJ12_RS02610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GJJ12_RS02615	COG2854	intermembrane phospholipid transfer
GJJ12_RS02620	COG3113	response to antibiotic
GJJ12_RS02625	COG5007	Belongs to the BolA IbaG family
GJJ12_RS02635	COG3423	Transcriptional regulator
GJJ12_RS02640	COG0142	geranyltranstransferase activity
GJJ12_RS02655	COG0697	spore germination
GJJ12_RS02665	COG2027	D-alanyl-D-alanine carboxypeptidase
GJJ12_RS02675	COG1534	Rna-binding protein
GJJ12_RS02685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GJJ12_RS02690	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GJJ12_RS02700	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GJJ12_RS02740	COG0195	Participates in both transcription termination and antitermination
GJJ12_RS02785	COG0814	amino acid
GJJ12_RS02790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GJJ12_RS02795	COG0826	peptidase U32
GJJ12_RS02800	COG0826	peptidase U32
GJJ12_RS02805	COG3154	lipid carrier protein
GJJ12_RS02810	COG3153	acetyltransferase
GJJ12_RS02825	COG0693	protein deglycase activity
GJJ12_RS02830	COG0702	epimerase
GJJ12_RS02835	COG0701	Predicted permease
GJJ12_RS02840	COG2823	Periplasmic or secreted lipoprotein
GJJ12_RS02860	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GJJ12_RS02865	COG2721	sulfolactate sulfo-lyase activity
GJJ12_RS02870	COG2271	Major facilitator Superfamily
GJJ12_RS02880	COG2084	Dehydrogenase
GJJ12_RS02885	COG1929	Belongs to the glycerate kinase type-1 family
GJJ12_RS02910	COG1741	Belongs to the pirin family
GJJ12_RS02915	COG0583	DNA-binding transcription factor activity
GJJ12_RS02920	COG3152	Membrane
GJJ12_RS02925	COG0435	Glutathione S-transferase
GJJ12_RS02930	COG2259	Doxx family
GJJ12_RS02940	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GJJ12_RS02945	COG4575	ribosome binding
GJJ12_RS02950	COG1422	Protein of unknown function (DUF1090)
GJJ12_RS02960	COG0586	Pfam SNARE associated Golgi protein
GJJ12_RS02965	COG2186	Transcriptional regulator
GJJ12_RS02970	COG2271	Major facilitator Superfamily
GJJ12_RS02980	COG2721	sulfolactate sulfo-lyase activity
GJJ12_RS02995	COG0861	Integral membrane protein TerC family
GJJ12_RS03000	COG0673	inositol 2-dehydrogenase activity
GJJ12_RS03005	COG1451	nucleotide metabolic process
GJJ12_RS03025	COG0446	pyridine nucleotide-disulphide oxidoreductase
GJJ12_RS03025	COG1902	pentaerythritol trinitrate reductase activity
GJJ12_RS03075	COG1695	Transcriptional regulator
GJJ12_RS03080	COG2375	cellular response to nickel ion
GJJ12_RS03095	COG1461	Dihydroxyacetone kinase
GJJ12_RS03100	COG2376	Dihydroxyacetone kinase
GJJ12_RS03170	COG3039	Transposase
GJJ12_RS03175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GJJ12_RS03180	COG1061	Type III restriction enzyme res subunit
GJJ12_RS03185	COG1002	Type II restriction enzyme, methylase subunits
GJJ12_RS03205	COG3596	GTP binding
GJJ12_RS03210	COG2378	regulation of single-species biofilm formation
GJJ12_RS03235	COG2003	Belongs to the UPF0758 family
GJJ12_RS03280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GJJ12_RS03285	COG0358	DNA primase activity
GJJ12_RS03290	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GJJ12_RS03360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GJJ12_RS03375	COG4991	sh3 domain protein
GJJ12_RS03380	COG3025	triphosphatase activity
GJJ12_RS03405	COG2960	long-chain fatty acid transporting porin activity
GJJ12_RS03420	COG3384	dioxygenase
GJJ12_RS03425	COG0754	glutathionylspermidine amidase activity
GJJ12_RS03440	COG0494	nUDIX hydrolase
GJJ12_RS03445	COG3151	Protein conserved in bacteria
GJJ12_RS03450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GJJ12_RS03455	COG3150	esterase
GJJ12_RS03465	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GJJ12_RS03470	COG2249	NAD(P)H dehydrogenase (quinone) activity
GJJ12_RS03475	COG0642	Histidine kinase
GJJ12_RS03485	COG3111	PFAM Bacterial OB fold (BOF) protein
GJJ12_RS03490	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GJJ12_RS03495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GJJ12_RS03500	COG0204	Acyl-transferase
GJJ12_RS03505	COG2132	Multicopper oxidase
GJJ12_RS03510	COG1032	radical SAM domain protein
GJJ12_RS03520	COG0656	L-ascorbic acid biosynthetic process
GJJ12_RS03525	COG1979	alcohol dehydrogenase
GJJ12_RS03530	COG2207	Transcriptional regulator
GJJ12_RS03535	COG0586	Pfam SNARE associated Golgi protein
GJJ12_RS03540	COG0626	cystathionine gamma-synthase activity
GJJ12_RS03555	COG0848	biopolymer transport protein
GJJ12_RS03560	COG2211	Major facilitator Superfamily
GJJ12_RS03585	COG0625	glutathione transferase activity
GJJ12_RS03600	COG0754	glutathionylspermidine amidase activity
GJJ12_RS03605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GJJ12_RS03625	COG0583	DNA-binding transcription factor activity
GJJ12_RS03630	COG0626	cystathionine gamma-synthase activity
GJJ12_RS03670	COG1811	Na channel or pump
GJJ12_RS03675	COG1982	Orn Lys Arg decarboxylase major
GJJ12_RS03680	COG2211	Major facilitator Superfamily
GJJ12_RS03695	COG1194	a g-specific adenine glycosylase
GJJ12_RS03705	COG3171	Protein conserved in bacteria
GJJ12_RS03715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GJJ12_RS03730	COG0762	integral membrane protein
GJJ12_RS03735	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GJJ12_RS03740	COG2805	Type II/IV secretion system protein
GJJ12_RS03760	COG0189	ligase activity
GJJ12_RS03765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GJJ12_RS03770	COG2356	endonuclease I
GJJ12_RS03780	COG2814	Major facilitator Superfamily
GJJ12_RS03815	COG2146	nitrite reductase [NAD(P)H] activity
GJJ12_RS03830	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS03835	COG1414	Transcriptional regulator
GJJ12_RS03865	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS03870	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
GJJ12_RS03890	COG0501	Belongs to the peptidase M48B family
GJJ12_RS03895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GJJ12_RS03910	COG0191	fructose-bisphosphate aldolase activity
GJJ12_RS03915	COG0668	transmembrane transport
GJJ12_RS03925	COG2968	Membrane
GJJ12_RS03940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GJJ12_RS03945	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GJJ12_RS03965	COG0006	proline dipeptidase activity
GJJ12_RS03970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GJJ12_RS03975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GJJ12_RS03995	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS04000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GJJ12_RS04020	COG2723	6-phospho-beta-galactosidase activity
GJJ12_RS04025	COG1737	Transcriptional regulator
GJJ12_RS04035	COG1272	protein, Hemolysin III
GJJ12_RS04045	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GJJ12_RS04055	COG0716	FMN binding
GJJ12_RS04060	COG4974	Belongs to the 'phage' integrase family
GJJ12_RS04070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GJJ12_RS04090	COG4942	peptidase
GJJ12_RS04100	COG2814	Major facilitator Superfamily
GJJ12_RS04115	COG0667	Aldo Keto reductase
GJJ12_RS04155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GJJ12_RS04160	COG1393	Belongs to the ArsC family
GJJ12_RS04175	COG1538	Outer membrane efflux protein
GJJ12_RS04180	COG1289	transmembrane transporter activity
GJJ12_RS04195	COG3592	Divergent 4Fe-4S mono-cluster
GJJ12_RS04200	COG2388	GCN5-related N-acetyl-transferase
GJJ12_RS04210	COG3539	Fimbrial protein
GJJ12_RS04215	COG3539	Fimbrial protein
GJJ12_RS04220	COG3539	Fimbrial protein
GJJ12_RS04225	COG3188	usher protein
GJJ12_RS04230	COG3121	Chaperone
GJJ12_RS04235	COG3539	Fimbrial protein
GJJ12_RS04245	COG4974	Belongs to the 'phage' integrase family
GJJ12_RS04270	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GJJ12_RS04275	COG1846	Transcriptional regulator
GJJ12_RS04280	COG0697	spore germination
GJJ12_RS04285	COG3039	Transposase
GJJ12_RS04325	COG1175	transmembrane transport
GJJ12_RS04330	COG1917	Cupin 2, conserved barrel domain protein
GJJ12_RS04335	COG1794	racemase activity, acting on amino acids and derivatives
GJJ12_RS04340	COG0583	DNA-binding transcription factor activity
GJJ12_RS04350	COG1609	Transcriptional regulator
GJJ12_RS04355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJJ12_RS04360	COG2723	6-phospho-beta-galactosidase activity
GJJ12_RS04365	COG2186	Transcriptional regulator
GJJ12_RS04375	COG1609	Transcriptional regulator
GJJ12_RS04395	COG0667	Aldo Keto reductase
GJJ12_RS04405	COG0861	Integral membrane protein TerC family
GJJ12_RS04440	COG2165	general secretion pathway protein
GJJ12_RS04445	COG4795	General secretion pathway protein
GJJ12_RS04455	COG4967	type IV pilus modification protein PilV
GJJ12_RS04460	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GJJ12_RS04465	COG1025	Belongs to the peptidase M16 family
GJJ12_RS04470	COG1074	ATP-dependent DNA helicase activity
GJJ12_RS04475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GJJ12_RS04485	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GJJ12_RS04485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GJJ12_RS04490	COG0860	N-Acetylmuramoyl-L-alanine amidase
GJJ12_RS04495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GJJ12_RS04525	COG4656	Part of a membrane complex involved in electron transport
GJJ12_RS04530	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS04530	COG1454	alcohol dehydrogenase
GJJ12_RS04560	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GJJ12_RS04715	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GJJ12_RS04720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GJJ12_RS04725	COG2166	iron-sulfur cluster assembly
GJJ12_RS04730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GJJ12_RS04740	COG0583	DNA-binding transcription factor activity
GJJ12_RS04745	COG2363	Small membrane protein
GJJ12_RS04755	COG1349	DNA-binding transcription factor activity
GJJ12_RS04775	COG0738	Major facilitator superfamily
GJJ12_RS04780	COG0235	Class ii aldolase
GJJ12_RS04785	COG1454	alcohol dehydrogenase
GJJ12_RS04805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GJJ12_RS04820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GJJ12_RS04825	COG2011	ABC-type metal ion transport system permease component
GJJ12_RS04830	COG1464	Belongs to the NlpA lipoprotein family
GJJ12_RS04835	COG0477	Major facilitator Superfamily
GJJ12_RS04845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GJJ12_RS04850	COG1760	l-serine dehydratase
GJJ12_RS04855	COG0814	amino acid
GJJ12_RS04860	COG1611	Belongs to the LOG family
GJJ12_RS04875	COG3098	single-species biofilm formation
GJJ12_RS04880	COG0564	pseudouridine synthase activity
GJJ12_RS04885	COG0716	FMN binding
GJJ12_RS04890	COG2271	Major facilitator Superfamily
GJJ12_RS04895	COG4948	Mandelate Racemase Muconate Lactonizing
GJJ12_RS04900	COG4948	Mandelate Racemase Muconate Lactonizing
GJJ12_RS04905	COG1929	Belongs to the glycerate kinase type-1 family
GJJ12_RS04910	COG3850	Histidine kinase
GJJ12_RS04910	COG3437	response regulator, receiver
GJJ12_RS04910	COG2205	protein histidine kinase activity
GJJ12_RS04910	COG4999	Histidine kinase
GJJ12_RS04920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GJJ12_RS04925	COG3956	TIGRFAM MazG family protein
GJJ12_RS04945	COG0602	queuosine metabolic process
GJJ12_RS04950	COG0720	synthase
GJJ12_RS04970	COG1203	CRISPR-associated helicase, Cas3
GJJ12_RS04985	COG1857	crispr-associated protein
GJJ12_RS05000	COG1518	maintenance of DNA repeat elements
GJJ12_RS05005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GJJ12_RS05020	COG2234	aminopeptidase activity
GJJ12_RS05080	COG1388	LysM domain
GJJ12_RS05080	COG4942	peptidase
GJJ12_RS05085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GJJ12_RS05110	COG0163	prenyltransferase activity
GJJ12_RS05115	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GJJ12_RS05140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJJ12_RS05145	COG4558	Periplasmic binding protein
GJJ12_RS05150	COG3720	iron ion transport
GJJ12_RS05175	COG0679	Auxin Efflux Carrier
GJJ12_RS05190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GJJ12_RS05195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GJJ12_RS05200	COG1121	(ABC) transporter
GJJ12_RS05210	COG1609	Transcriptional regulator
GJJ12_RS05215	COG1940	carbohydrate kinase activity
GJJ12_RS05220	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJJ12_RS05225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJJ12_RS05230	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJJ12_RS05235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJJ12_RS05240	COG4580	involved in the transport of maltose and maltodextrins
GJJ12_RS05250	COG2723	6-phospho-beta-galactosidase activity
GJJ12_RS05260	COG0309	Hydrogenase expression formation protein (HypE)
GJJ12_RS05265	COG0409	Hydrogenase expression formation protein
GJJ12_RS05270	COG0298	carbon dioxide binding
GJJ12_RS05275	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GJJ12_RS05290	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GJJ12_RS05295	COG0651	ATP synthesis coupled electron transport
GJJ12_RS05300	COG0650	Formate hydrogenlyase subunit 4
GJJ12_RS05305	COG3261	NADH dehydrogenase
GJJ12_RS05305	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GJJ12_RS05310	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GJJ12_RS05315	COG3260	NADH ubiquinone oxidoreductase 20
GJJ12_RS05325	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GJJ12_RS05335	COG2723	6-phospho-beta-galactosidase activity
GJJ12_RS05340	COG1263	PTS System
GJJ12_RS05340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJJ12_RS05345	COG1609	Transcriptional regulator
GJJ12_RS05350	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GJJ12_RS05355	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GJJ12_RS05360	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GJJ12_RS05385	COG1349	DNA-binding transcription factor activity
GJJ12_RS05390	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJJ12_RS05395	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS05405	COG3732	PTS system glucitol sorbitol-specific
GJJ12_RS05410	COG3730	PTS system glucitol sorbitol-specific
GJJ12_RS05415	COG2951	lytic endotransglycosylase activity
GJJ12_RS05420	COG1121	(ABC) transporter
GJJ12_RS05425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GJJ12_RS05435	COG1546	Belongs to the CinA family
GJJ12_RS05455	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GJJ12_RS05490	COG2823	Periplasmic or secreted lipoprotein
GJJ12_RS05495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GJJ12_RS05500	COG1238	metal cluster binding
GJJ12_RS05520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GJJ12_RS05525	COG2814	Major facilitator Superfamily
GJJ12_RS05530	COG1566	PFAM secretion protein HlyD family protein
GJJ12_RS05535	COG1846	Transcriptional regulator
GJJ12_RS05545	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GJJ12_RS05555	COG4176	ABC-type proline glycine betaine transport system permease component
GJJ12_RS05570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GJJ12_RS05580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GJJ12_RS05585	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GJJ12_RS05590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GJJ12_RS05595	COG4575	ribosome binding
GJJ12_RS05610	COG2916	Histone family protein nucleoid-structuring protein H-NS
GJJ12_RS05625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GJJ12_RS05630	COG0640	Transcriptional regulator
GJJ12_RS05640	COG0583	DNA-binding transcription factor activity
GJJ12_RS05645	COG3284	Transcriptional regulator
GJJ12_RS05655	COG3539	Fimbrial protein
GJJ12_RS05660	COG3121	Chaperone
GJJ12_RS05695	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS05705	COG0235	Class ii aldolase
GJJ12_RS05715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJJ12_RS05750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJJ12_RS05755	COG3708	Transcriptional regulator
GJJ12_RS05755	COG2207	Transcriptional regulator
GJJ12_RS05820	COG0582	viral genome integration into host DNA
GJJ12_RS05835	COG2867	negative regulation of translational initiation
GJJ12_RS05850	COG0497	DNA recombination
GJJ12_RS05865	COG4536	flavin adenine dinucleotide binding
GJJ12_RS05870	COG4137	Cytochrome C assembly protein
GJJ12_RS05875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GJJ12_RS05910	COG2885	chlorophyll binding
GJJ12_RS05915	COG2199	diguanylate cyclase activity
GJJ12_RS05925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GJJ12_RS05930	COG1605	Chorismate mutase
GJJ12_RS05930	COG0287	Prephenate dehydrogenase
GJJ12_RS05940	COG1605	Chorismate mutase
GJJ12_RS05940	COG0077	Prephenate dehydratase
GJJ12_RS05950	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GJJ12_RS05955	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GJJ12_RS05970	COG0542	response to heat
GJJ12_RS05995	COG0477	Major facilitator Superfamily
GJJ12_RS06000	COG5544	Lipoprotein
GJJ12_RS06005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GJJ12_RS06015	COG3148	PFAM DTW domain containing protein
GJJ12_RS06020	COG3118	belongs to the thioredoxin family
GJJ12_RS06025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJJ12_RS06040	COG0513	Belongs to the DEAD box helicase family
GJJ12_RS06050	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GJJ12_RS06065	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GJJ12_RS06070	COG3026	antisigma factor binding
GJJ12_RS06075	COG3086	response to oxidative stress
GJJ12_RS06085	COG0681	Belongs to the peptidase S26 family
GJJ12_RS06105	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GJJ12_RS06115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GJJ12_RS06120	COG1737	Transcriptional regulator
GJJ12_RS06125	COG0560	Phosphoserine phosphatase
GJJ12_RS06140	COG0047	phosphoribosylformylglycinamidine synthase activity
GJJ12_RS06140	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GJJ12_RS06145	COG2205	protein histidine kinase activity
GJJ12_RS06150	COG3170	Tfp pilus assembly protein FimV
GJJ12_RS06155	COG2204	response regulator
GJJ12_RS06160	COG0347	Belongs to the P(II) protein family
GJJ12_RS06165	COG1017	nitric oxide dioxygenase activity
GJJ12_RS06165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GJJ12_RS06175	COG2259	Doxx family
GJJ12_RS06180	COG1940	carbohydrate kinase activity
GJJ12_RS06185	COG0457	Tetratricopeptide repeat
GJJ12_RS06190	COG0477	Major facilitator Superfamily
GJJ12_RS06190	COG2814	Major facilitator Superfamily
GJJ12_RS06195	COG2017	converts alpha-aldose to the beta-anomer
GJJ12_RS06200	COG2814	Major facilitator Superfamily
GJJ12_RS06205	COG3711	transcriptional antiterminator
GJJ12_RS06210	COG3683	transport system, periplasmic component
GJJ12_RS06215	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GJJ12_RS06245	COG0822	iron-sulfur transferase activity
GJJ12_RS06265	COG0633	Ferredoxin
GJJ12_RS06270	COG2975	iron-sulfur cluster assembly
GJJ12_RS06290	COG2897	thiosulfate sulfurtransferase activity
GJJ12_RS06295	COG2373	Large extracellular alpha-helical protein
GJJ12_RS06300	COG4953	penicillin-binding protein 1C
GJJ12_RS06330	COG2976	Protein conserved in bacteria
GJJ12_RS06350	COG1645	bacterial-type flagellum-dependent swarming motility
GJJ12_RS06360	COG0516	GMP reductase activity
GJJ12_RS06360	COG0517	IMP dehydrogenase activity
GJJ12_RS06370	COG3119	arylsulfatase activity
GJJ12_RS06375	COG0641	radical SAM
GJJ12_RS06410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GJJ12_RS06425	COG2723	6-phospho-beta-galactosidase activity
GJJ12_RS06435	COG2233	PERMEase
GJJ12_RS06450	COG1393	Belongs to the ArsC family
GJJ12_RS06455	COG4783	chaperone-mediated protein folding
GJJ12_RS06465	COG0628	permease
GJJ12_RS06470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GJJ12_RS06475	COG2716	regulation of RNA biosynthetic process
GJJ12_RS06485	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GJJ12_RS06495	COG2321	neutral zinc metallopeptidase
GJJ12_RS06500	COG1444	tRNA N-acetyltransferase activity
GJJ12_RS06505	COG0400	carboxylic ester hydrolase activity
GJJ12_RS06520	COG1393	Belongs to the ArsC family
GJJ12_RS06530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GJJ12_RS06535	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GJJ12_RS06535	COG0493	'glutamate synthase
GJJ12_RS06545	COG5342	invasion associated locus B
GJJ12_RS06550	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GJJ12_RS06555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GJJ12_RS06565	COG4810	utilization protein
GJJ12_RS06655	COG0860	N-Acetylmuramoyl-L-alanine amidase
GJJ12_RS06675	COG2837	iron assimilation
GJJ12_RS06685	COG4150	thiosulfate binding
GJJ12_RS06690	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GJJ12_RS06695	COG4208	sulfate ABC transporter
GJJ12_RS06700	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GJJ12_RS06710	COG4319	ketosteroid isomerase
GJJ12_RS06745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GJJ12_RS06765	COG3530	Putative quorum-sensing-regulated virulence factor
GJJ12_RS06770	COG0385	Bile acid
GJJ12_RS06775	COG0583	DNA-binding transcription factor activity
GJJ12_RS06800	COG3415	Transposase
GJJ12_RS06805	COG3415	Transposase
GJJ12_RS06820	COG2200	EAL domain
GJJ12_RS06820	COG2199	diguanylate cyclase activity
GJJ12_RS06825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GJJ12_RS06840	COG0667	Aldo Keto reductase
GJJ12_RS06845	COG3961	Belongs to the TPP enzyme family
GJJ12_RS06860	COG3279	Response regulator of the LytR AlgR family
GJJ12_RS06865	COG3275	phosphorelay sensor kinase activity
GJJ12_RS06880	COG0436	Aminotransferase
GJJ12_RS06890	COG2807	transmembrane transport
GJJ12_RS06895	COG0590	tRNA wobble adenosine to inosine editing
GJJ12_RS06900	COG0583	DNA-binding transcription factor activity
GJJ12_RS06940	COG2885	chlorophyll binding
GJJ12_RS06975	COG4372	Transposase
GJJ12_RS06980	COG3436	PFAM IS66 Orf2 family protein
GJJ12_RS07180	COG0582	viral genome integration into host DNA
GJJ12_RS07190	COG2116	formate transmembrane transporter activity
GJJ12_RS07195	COG2853	Lipoprotein
GJJ12_RS07205	COG3691	Protein conserved in bacteria
GJJ12_RS07220	COG2062	phosphohistidine phosphatase, SixA
GJJ12_RS07245	COG0730	response to heat
GJJ12_RS07250	COG3101	peptidyl-lysine hydroxylation
GJJ12_RS07265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GJJ12_RS07285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GJJ12_RS07295	COG0586	Pfam SNARE associated Golgi protein
GJJ12_RS07305	COG0285	dihydrofolate synthase activity
GJJ12_RS07310	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GJJ12_RS07315	COG1286	toxin biosynthetic process
GJJ12_RS07320	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GJJ12_RS07325	COG0163	prenyltransferase activity
GJJ12_RS07350	COG4160	amino acid transport
GJJ12_RS07355	COG4598	ABC transporter
GJJ12_RS07370	COG1090	epimerase
GJJ12_RS07375	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GJJ12_RS07380	COG0625	glutathione transferase activity
GJJ12_RS07385	COG0625	glutathione transferase activity
GJJ12_RS07390	COG0622	Phosphoesterase
GJJ12_RS07395	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GJJ12_RS07400	COG0857	belongs to the CobB CobQ family
GJJ12_RS07400	COG0280	phosphate acetyltransferase
GJJ12_RS07420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GJJ12_RS07425	COG0471	metal ion transport
GJJ12_RS07425	COG0490	domain, Protein
GJJ12_RS07435	COG0436	Aminotransferase
GJJ12_RS07440	COG0583	DNA-binding transcription factor activity
GJJ12_RS07485	COG0839	Belongs to the complex I subunit 6 family
GJJ12_RS07495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GJJ12_RS07500	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GJJ12_RS07515	COG2153	protein acetylation
GJJ12_RS07520	COG1169	isochorismate synthase
GJJ12_RS07545	COG0318	PFAM AMP-dependent synthetase and ligase
GJJ12_RS07555	COG5464	transposase or invertase
GJJ12_RS07570	COG1414	Transcriptional regulator
GJJ12_RS07580	COG2271	Major facilitator Superfamily
GJJ12_RS07590	COG0247	lactate metabolic process
GJJ12_RS07600	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GJJ12_RS07605	COG2271	Major facilitator Superfamily
GJJ12_RS07610	COG0584	glycerophosphoryl diester phosphodiesterase
GJJ12_RS07615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GJJ12_RS07640	COG0784	Response regulator, receiver
GJJ12_RS07640	COG2205	protein histidine kinase activity
GJJ12_RS07650	COG2198	Histidine kinase
GJJ12_RS07650	COG0642	Histidine kinase
GJJ12_RS07670	COG3145	DNA-N1-methyladenine dioxygenase activity
GJJ12_RS07675	COG4615	Cyclic peptide transporter
GJJ12_RS07680	COG2239	Acts as a magnesium transporter
GJJ12_RS07685	COG0659	secondary active sulfate transmembrane transporter activity
GJJ12_RS07700	COG0628	permease
GJJ12_RS07725	COG1349	DNA-binding transcription factor activity
GJJ12_RS07730	COG0494	nUDIX hydrolase
GJJ12_RS07750	COG1061	Type III restriction enzyme res subunit
GJJ12_RS07755	COG1187	pseudouridine synthase activity
GJJ12_RS07760	COG2814	Major facilitator Superfamily
GJJ12_RS07770	COG4172	Belongs to the ABC transporter superfamily
GJJ12_RS07775	COG4239	(ABC) transporter, permease
GJJ12_RS07780	COG4174	ABC transporter (Permease)
GJJ12_RS07785	COG4166	transmembrane transport
GJJ12_RS07790	COG2200	EAL domain
GJJ12_RS07795	COG0791	NLP P60 protein
GJJ12_RS07800	COG0671	phosphoesterase, PA-phosphatase related
GJJ12_RS07805	COG0523	cobalamin synthesis protein
GJJ12_RS07810	COG0246	Mannitol dehydrogenase
GJJ12_RS07815	COG1312	Catalyzes the dehydration of D-mannonate
GJJ12_RS07835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJJ12_RS07835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJJ12_RS07840	COG1105	Belongs to the carbohydrate kinase PfkB family
GJJ12_RS07845	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GJJ12_RS07845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GJJ12_RS07845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GJJ12_RS07855	COG2855	membrane
GJJ12_RS07860	COG0583	DNA-binding transcription factor activity
GJJ12_RS07865	COG0833	amino acid
GJJ12_RS07885	COG2311	Membrane
GJJ12_RS07900	COG1129	ABC transporter
GJJ12_RS07910	COG2949	membrane
GJJ12_RS07920	COG1346	cytolysis
GJJ12_RS07930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GJJ12_RS07935	COG3659	wide pore channel activity
GJJ12_RS07950	COG2723	6-phospho-beta-galactosidase activity
GJJ12_RS07955	COG1538	Outer membrane efflux protein
GJJ12_RS07960	COG0586	Pfam SNARE associated Golgi protein
GJJ12_RS07970	COG1686	Belongs to the peptidase S11 family
GJJ12_RS07980	COG0277	FAD linked oxidase domain protein
GJJ12_RS07985	COG1472	Belongs to the glycosyl hydrolase 3 family
GJJ12_RS07990	COG1732	Glycine betaine
GJJ12_RS07995	COG1174	glycine betaine transport
GJJ12_RS08000	COG1125	glycine betaine transport
GJJ12_RS08005	COG1174	glycine betaine transport
GJJ12_RS08015	COG3275	phosphorelay sensor kinase activity
GJJ12_RS08025	COG4807	Protein conserved in bacteria
GJJ12_RS08045	COG5455	response to cobalt ion
GJJ12_RS08050	COG0583	DNA-binding transcription factor activity
GJJ12_RS08055	COG2252	PERMEase
GJJ12_RS08065	COG0583	DNA-binding transcription factor activity
GJJ12_RS08080	COG0351	phosphomethylpyrimidine kinase
GJJ12_RS08085	COG2188	Transcriptional regulator
GJJ12_RS08090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GJJ12_RS08095	COG1397	ADP-ribosylglycohydrolase
GJJ12_RS08100	COG2211	Major facilitator Superfamily
GJJ12_RS08105	COG1830	Aldolase
GJJ12_RS08120	COG0826	peptidase U32
GJJ12_RS08125	COG0745	RESPONSE REGULATOR receiver
GJJ12_RS08130	COG2205	protein histidine kinase activity
GJJ12_RS08155	COG1301	dicarboxylic acid transport
GJJ12_RS08175	COG5002	protein histidine kinase activity
GJJ12_RS08180	COG0443	Heat shock 70 kDa protein
GJJ12_RS08185	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GJJ12_RS08200	COG2982	Protein involved in outer membrane biogenesis
GJJ12_RS08205	COG1253	flavin adenine dinucleotide binding
GJJ12_RS08250	COG0438	transferase activity, transferring glycosyl groups
GJJ12_RS08255	COG0438	transferase activity, transferring glycosyl groups
GJJ12_RS08265	COG0438	transferase activity, transferring glycosyl groups
GJJ12_RS08270	COG0438	transferase activity, transferring glycosyl groups
GJJ12_RS08345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GJJ12_RS08360	COG2271	Major facilitator Superfamily
GJJ12_RS08365	COG0246	Mannitol dehydrogenase
GJJ12_RS08370	COG0589	response to stress
GJJ12_RS08375	COG1802	Transcriptional regulator
GJJ12_RS08380	COG4221	oxidoreductase activity
GJJ12_RS08385	COG0339	signal peptide processing
GJJ12_RS08395	COG2207	Transcriptional regulator
GJJ12_RS08400	COG2135	peptidase activity
GJJ12_RS08430	COG0071	Belongs to the small heat shock protein (HSP20) family
GJJ12_RS08435	COG1546	Belongs to the CinA family
GJJ12_RS08440	COG2200	EAL domain
GJJ12_RS08460	COG2207	Transcriptional regulator
GJJ12_RS08460	COG3708	Transcriptional regulator
GJJ12_RS08465	COG2610	gluconate transmembrane transporter activity
GJJ12_RS08470	COG3622	Belongs to the hyi family
GJJ12_RS08475	COG0235	Class ii aldolase
GJJ12_RS08480	COG3395	kinase activity
GJJ12_RS08485	COG2084	Dehydrogenase
GJJ12_RS08490	COG1349	DNA-binding transcription factor activity
GJJ12_RS08505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GJJ12_RS08510	COG2223	nitrite transmembrane transporter activity
GJJ12_RS08545	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GJJ12_RS08550	COG0683	leucine binding
GJJ12_RS08565	COG1129	ABC transporter
GJJ12_RS08580	COG2814	Major facilitator Superfamily
GJJ12_RS08585	COG0697	spore germination
GJJ12_RS08595	COG4977	sequence-specific DNA binding
GJJ12_RS08645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GJJ12_RS08650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GJJ12_RS08660	COG3395	kinase activity
GJJ12_RS08665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GJJ12_RS08670	COG1349	DNA-binding transcription factor activity
GJJ12_RS08675	COG0039	L-malate dehydrogenase activity
GJJ12_RS08685	COG0583	DNA-binding transcription factor activity
GJJ12_RS08690	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS08705	COG2199	diguanylate cyclase activity
GJJ12_RS08755	COG0477	Major facilitator Superfamily
GJJ12_RS08765	COG2070	2-Nitropropane dioxygenase
GJJ12_RS08770	COG2011	ABC-type metal ion transport system permease component
GJJ12_RS08790	COG4628	conserved protein (DUF2132)
GJJ12_RS08805	COG2207	Transcriptional regulator
GJJ12_RS08835	COG2233	PERMEase
GJJ12_RS08840	COG3195	allantoin biosynthetic process
GJJ12_RS08840	COG3648	Uricase
GJJ12_RS08845	COG2351	hydroxyisourate hydrolase activity
GJJ12_RS08850	COG1396	sequence-specific DNA binding
GJJ12_RS08855	COG3550	peptidyl-serine autophosphorylation
GJJ12_RS08860	COG1649	PFAM Uncharacterised BCR, COG1649
GJJ12_RS08870	COG3188	usher protein
GJJ12_RS08910	COG5001	Diguanylate cyclase
GJJ12_RS08910	COG3300	MHYT domain
GJJ12_RS08915	COG2819	hydrolase of the alpha beta superfamily
GJJ12_RS08930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJJ12_RS08930	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJJ12_RS08935	COG2814	Major facilitator Superfamily
GJJ12_RS08945	COG1263	PTS System
GJJ12_RS08945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJJ12_RS08950	COG2186	Transcriptional regulator
GJJ12_RS08960	COG0583	DNA-binding transcription factor activity
GJJ12_RS08970	COG3835	regulator
GJJ12_RS08975	COG1929	Belongs to the glycerate kinase type-1 family
GJJ12_RS09020	COG0738	Major facilitator superfamily
GJJ12_RS09025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GJJ12_RS09030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GJJ12_RS09035	COG1349	DNA-binding transcription factor activity
GJJ12_RS09050	COG1349	DNA-binding transcription factor activity
GJJ12_RS09075	COG4977	sequence-specific DNA binding
GJJ12_RS09115	COG2826	transposase and inactivated derivatives, IS30 family
GJJ12_RS09120	COG0667	Aldo Keto reductase
GJJ12_RS09125	COG3386	PFAM SMP-30 Gluconolaconase
GJJ12_RS09130	COG0667	Aldo Keto reductase
GJJ12_RS09135	COG0667	Aldo Keto reductase
GJJ12_RS09145	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GJJ12_RS09145	COG0456	acetyltransferase
GJJ12_RS09170	COG1652	LysM domain
GJJ12_RS09200	COG1609	Transcriptional regulator
GJJ12_RS09210	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS09225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GJJ12_RS09235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GJJ12_RS09240	COG0583	DNA-binding transcription factor activity
GJJ12_RS09245	COG0583	DNA-binding transcription factor activity
GJJ12_RS09260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GJJ12_RS09260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GJJ12_RS09260	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GJJ12_RS09275	COG1609	Transcriptional regulator
GJJ12_RS09285	COG2223	nitrite transmembrane transporter activity
GJJ12_RS09330	COG0477	Major facilitator Superfamily
GJJ12_RS09335	COG4529	Protein conserved in bacteria
GJJ12_RS09340	COG1902	pentaerythritol trinitrate reductase activity
GJJ12_RS09350	COG0583	DNA-binding transcription factor activity
GJJ12_RS09355	COG2070	2-Nitropropane dioxygenase
GJJ12_RS09365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GJJ12_RS09375	COG0765	amino acid transport
GJJ12_RS09445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GJJ12_RS09460	COG2207	Transcriptional regulator
GJJ12_RS09470	COG0596	Alpha beta hydrolase
GJJ12_RS09505	COG1953	Uracil, thiamine, allantoin
GJJ12_RS09510	COG0402	S-adenosylhomocysteine deaminase activity
GJJ12_RS09515	COG3706	GGDEF domain
GJJ12_RS09520	COG1609	Transcriptional regulator
GJJ12_RS09530	COG0673	inositol 2-dehydrogenase activity
GJJ12_RS09545	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GJJ12_RS09550	COG1116	anion transmembrane transporter activity
GJJ12_RS09555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GJJ12_RS09560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GJJ12_RS09565	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GJJ12_RS09570	COG0076	glutamate decarboxylase activity
GJJ12_RS09585	COG2205	protein histidine kinase activity
GJJ12_RS09595	COG0596	Alpha beta hydrolase
GJJ12_RS09635	COG0519	Catalyzes the synthesis of GMP from XMP
GJJ12_RS09635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GJJ12_RS09655	COG0583	DNA-binding transcription factor activity
GJJ12_RS09665	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GJJ12_RS09670	COG1285	pathogenesis
GJJ12_RS09675	COG2814	Major facilitator Superfamily
GJJ12_RS09680	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJJ12_RS09685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJJ12_RS09695	COG3039	Transposase
GJJ12_RS09720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJJ12_RS09725	COG0583	DNA-binding transcription factor activity
GJJ12_RS09730	COG0243	molybdopterin cofactor binding
GJJ12_RS09735	COG3781	membrane
GJJ12_RS09760	COG1764	response to oxidative stress
GJJ12_RS09770	COG3111	PFAM Bacterial OB fold (BOF) protein
GJJ12_RS09780	COG2323	membrane
GJJ12_RS09790	COG0366	Alpha amylase catalytic
GJJ12_RS09800	COG3685	Protein conserved in bacteria
GJJ12_RS09810	COG3729	General stress protein
GJJ12_RS09815	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS09860	COG0488	(ABC) transporter
GJJ12_RS09875	COG1064	alcohol dehydrogenase
GJJ12_RS09880	COG0747	negative chemotaxis
GJJ12_RS09890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJJ12_RS09900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GJJ12_RS09910	COG2814	Major facilitator Superfamily
GJJ12_RS09920	COG2326	polyphosphate kinase activity
GJJ12_RS09935	COG2864	formate dehydrogenase
GJJ12_RS09940	COG0437	4 iron, 4 sulfur cluster binding
GJJ12_RS09965	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GJJ12_RS09975	COG3485	protocatechuate 3,4-dioxygenase
GJJ12_RS09980	COG4829	muconolactone delta-isomerase
GJJ12_RS09985	COG4948	Mandelate Racemase Muconate Lactonizing
GJJ12_RS09990	COG1414	Transcriptional regulator
GJJ12_RS10010	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GJJ12_RS10015	COG1140	nitrate reductase beta subunit
GJJ12_RS10020	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GJJ12_RS10025	COG2181	nitrate reductase activity
GJJ12_RS10030	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GJJ12_RS10035	COG1178	ABC-type Fe3 transport system permease component
GJJ12_RS10040	COG1840	ABC-type Fe3 transport system, periplasmic component
GJJ12_RS10045	COG3842	ATPase activity
GJJ12_RS10050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GJJ12_RS10065	COG2211	Major facilitator Superfamily
GJJ12_RS10090	COG0625	glutathione transferase activity
GJJ12_RS10100	COG1126	abc transporter atp-binding protein
GJJ12_RS10105	COG0765	amino acid transport
GJJ12_RS10115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJJ12_RS10120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GJJ12_RS10125	COG1473	amidohydrolase
GJJ12_RS10130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GJJ12_RS10135	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GJJ12_RS10160	COG4772	TonB-dependent receptor
GJJ12_RS10165	COG1228	amidohydrolase
GJJ12_RS10170	COG3691	Protein conserved in bacteria
GJJ12_RS10185	COG2130	NADP-dependent
GJJ12_RS10195	COG1247	-acetyltransferase
GJJ12_RS10200	COG3238	Protein conserved in bacteria
GJJ12_RS10210	COG0747	negative chemotaxis
GJJ12_RS10215	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS10250	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS10255	COG1177	transmembrane transport
GJJ12_RS10260	COG1176	ABC-type spermidine putrescine transport system, permease component I
GJJ12_RS10265	COG3842	ATPase activity
GJJ12_RS10270	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GJJ12_RS10275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GJJ12_RS10280	COG1271	oxidase subunit
GJJ12_RS10285	COG1294	oxidase, subunit
GJJ12_RS10305	COG0826	peptidase U32
GJJ12_RS10315	COG1396	sequence-specific DNA binding
GJJ12_RS10320	COG3135	benzoate transporter
GJJ12_RS10325	COG3708	Transcriptional regulator
GJJ12_RS10325	COG2207	Transcriptional regulator
GJJ12_RS10330	COG0697	spore germination
GJJ12_RS10340	COG0500	methyltransferase
GJJ12_RS10345	COG1275	C4-dicarboxylate transporter malic acid transport protein
GJJ12_RS10350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GJJ12_RS10355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GJJ12_RS10370	COG2272	Belongs to the type-B carboxylesterase lipase family
GJJ12_RS10375	COG5383	Protein conserved in bacteria
GJJ12_RS10380	COG3485	protocatechuate 3,4-dioxygenase
GJJ12_RS10385	COG3485	protocatechuate 3,4-dioxygenase
GJJ12_RS10390	COG0583	DNA-binding transcription factor activity
GJJ12_RS10410	COG3038	cytochrome b561
GJJ12_RS10430	COG2814	Major facilitator Superfamily
GJJ12_RS10440	COG0673	inositol 2-dehydrogenase activity
GJJ12_RS10450	COG2723	6-phospho-beta-galactosidase activity
GJJ12_RS10485	COG4659	FMN binding
GJJ12_RS10495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GJJ12_RS10505	COG0625	glutathione transferase activity
GJJ12_RS10510	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GJJ12_RS10525	COG3895	Periplasmic Protein
GJJ12_RS10540	COG3706	GGDEF domain
GJJ12_RS10555	COG1566	PFAM secretion protein HlyD family protein
GJJ12_RS10560	COG1289	transmembrane transporter activity
GJJ12_RS10565	COG2032	superoxide dismutase activity
GJJ12_RS10570	COG4989	oxidoreductase activity
GJJ12_RS10575	COG3313	Fe-S protein
GJJ12_RS10580	COG1309	transcriptional regulator
GJJ12_RS10585	COG1902	pentaerythritol trinitrate reductase activity
GJJ12_RS10590	COG0346	lactoylglutathione lyase activity
GJJ12_RS10600	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GJJ12_RS10605	COG0791	NLP P60 protein
GJJ12_RS10620	COG2814	Major facilitator Superfamily
GJJ12_RS10635	COG0583	DNA-binding transcription factor activity
GJJ12_RS10645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GJJ12_RS10650	COG0307	riboflavin synthase, alpha
GJJ12_RS10695	COG0300	oxidoreductase activity
GJJ12_RS10715	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GJJ12_RS10750	COG1349	DNA-binding transcription factor activity
GJJ12_RS10755	COG0346	lactoylglutathione lyase activity
GJJ12_RS10780	COG0444	Belongs to the ABC transporter superfamily
GJJ12_RS10785	COG4608	Belongs to the ABC transporter superfamily
GJJ12_RS10810	COG0583	DNA-binding transcription factor activity
GJJ12_RS10840	COG0402	S-adenosylhomocysteine deaminase activity
GJJ12_RS10865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GJJ12_RS10870	COG0277	FAD linked oxidase domain protein
GJJ12_RS10885	COG2814	Major facilitator Superfamily
GJJ12_RS10915	COG0583	DNA-binding transcription factor activity
GJJ12_RS10925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GJJ12_RS10935	COG1250	3-hydroxyacyl-CoA dehydrogenase
GJJ12_RS10940	COG2610	gluconate transmembrane transporter activity
GJJ12_RS10945	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS11005	COG4235	cytochrome complex assembly
GJJ12_RS11005	COG3088	subunit of a heme lyase
GJJ12_RS11010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GJJ12_RS11015	COG1138	Cytochrome C-type biogenesis protein
GJJ12_RS11030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GJJ12_RS11035	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GJJ12_RS11040	COG4133	protoheme IX ABC transporter activity
GJJ12_RS11070	COG1175	transmembrane transport
GJJ12_RS11080	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GJJ12_RS11085	COG3383	formate dehydrogenase (NAD+) activity
GJJ12_RS11125	COG1126	abc transporter atp-binding protein
GJJ12_RS11130	COG0765	amino acid transport
GJJ12_RS11150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJJ12_RS11155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJJ12_RS11160	COG1120	ATPase activity
GJJ12_RS11165	COG4774	siderophore transport
GJJ12_RS11170	COG1116	anion transmembrane transporter activity
GJJ12_RS11175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GJJ12_RS11195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GJJ12_RS11200	COG0583	DNA-binding transcription factor activity
GJJ12_RS11220	COG2814	Major facilitator Superfamily
GJJ12_RS11255	COG1414	Transcriptional regulator
GJJ12_RS11260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GJJ12_RS11265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJJ12_RS11270	COG1120	ATPase activity
GJJ12_RS11280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GJJ12_RS11285	COG2271	Major facilitator Superfamily
GJJ12_RS11290	COG1082	Xylose isomerase domain protein TIM barrel
GJJ12_RS11290	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GJJ12_RS11295	COG1309	transcriptional regulator
GJJ12_RS11325	COG1376	ErfK ybiS ycfS ynhG family protein
GJJ12_RS11340	COG0719	Fe-S assembly protein
GJJ12_RS11345	COG0396	ATPase activity
GJJ12_RS11350	COG0719	Fe-S assembly protein
GJJ12_RS11355	COG0316	Belongs to the HesB IscA family
GJJ12_RS11370	COG1304	FMN binding
GJJ12_RS11395	COG0583	DNA-binding transcription factor activity
GJJ12_RS11405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJJ12_RS11410	COG1120	ATPase activity
GJJ12_RS11435	COG2261	transglycosylase associated protein
GJJ12_RS11440	COG2050	protein possibly involved in aromatic compounds catabolism
GJJ12_RS11445	COG0247	lactate metabolic process
GJJ12_RS11445	COG0277	FAD linked oxidase domain protein
GJJ12_RS11450	COG0628	permease
GJJ12_RS11460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GJJ12_RS11460	COG0574	Belongs to the PEP-utilizing enzyme family
GJJ12_RS11475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GJJ12_RS11480	COG4256	Hemin uptake protein
GJJ12_RS11490	COG0791	NLP P60 protein
GJJ12_RS11500	COG0386	Belongs to the glutathione peroxidase family
GJJ12_RS11520	COG0583	DNA-binding transcription factor activity
GJJ12_RS11540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJJ12_RS11540	COG0072	phenylalanine-tRNA ligase activity
GJJ12_RS11580	COG3137	Salt-induced outer membrane protein
GJJ12_RS11585	COG1105	Belongs to the carbohydrate kinase PfkB family
GJJ12_RS11595	COG3001	Fructosamine kinase
GJJ12_RS11605	COG2350	Protein conserved in bacteria
GJJ12_RS11615	COG2353	YceI-like domain
GJJ12_RS11635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GJJ12_RS11645	COG0444	Belongs to the ABC transporter superfamily
GJJ12_RS11650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJJ12_RS11655	COG0601	transmembrane transport
GJJ12_RS11660	COG4166	transmembrane transport
GJJ12_RS11665	COG2095	MarC family integral membrane protein
GJJ12_RS11675	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS11675	COG1454	alcohol dehydrogenase
GJJ12_RS11680	COG1435	thymidine kinase activity
GJJ12_RS11690	COG2916	Histone family protein nucleoid-structuring protein H-NS
GJJ12_RS11695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GJJ12_RS11700	COG0745	RESPONSE REGULATOR receiver
GJJ12_RS11705	COG1752	Esterase of the alpha-beta hydrolase superfamily
GJJ12_RS11715	COG0788	formyltetrahydrofolate deformylase activity
GJJ12_RS11750	COG1522	sequence-specific DNA binding
GJJ12_RS11760	COG2181	nitrate reductase activity
GJJ12_RS11765	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GJJ12_RS11770	COG1140	nitrate reductase beta subunit
GJJ12_RS11775	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GJJ12_RS11785	COG2223	nitrite transmembrane transporter activity
GJJ12_RS11790	COG3850	Histidine kinase
GJJ12_RS11795	COG2197	response regulator
GJJ12_RS11800	COG4932	domain protein
GJJ12_RS11805	COG0243	molybdopterin cofactor binding
GJJ12_RS11810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GJJ12_RS11810	COG2146	nitrite reductase [NAD(P)H] activity
GJJ12_RS11815	COG1116	anion transmembrane transporter activity
GJJ12_RS11825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GJJ12_RS11830	COG3707	response regulator
GJJ12_RS11835	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GJJ12_RS11845	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GJJ12_RS11850	COG4572	Cation transport regulator
GJJ12_RS11855	COG0387	Pfam Sodium calcium exchanger
GJJ12_RS11875	COG2890	protein-(glutamine-N5) methyltransferase activity
GJJ12_RS11905	COG0659	secondary active sulfate transmembrane transporter activity
GJJ12_RS11925	COG0012	GTP binding
GJJ12_RS12030	COG2885	chlorophyll binding
GJJ12_RS12050	COG3122	Protein conserved in bacteria
GJJ12_RS12170	COG0740	serine-type endopeptidase activity
GJJ12_RS12175	COG4695	Portal protein
GJJ12_RS12180	COG4626	Terminase
GJJ12_RS12180	COG1802	Transcriptional regulator
GJJ12_RS12255	COG0484	heat shock protein binding
GJJ12_RS12260	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GJJ12_RS12270	COG1484	DNA-dependent DNA replication
GJJ12_RS12360	COG0582	viral genome integration into host DNA
GJJ12_RS12365	COG0583	DNA-binding transcription factor activity
GJJ12_RS12395	COG0583	DNA-binding transcription factor activity
GJJ12_RS12430	COG1882	Formate acetyltransferase
GJJ12_RS12445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GJJ12_RS12450	COG0583	DNA-binding transcription factor activity
GJJ12_RS12490	COG2308	Evidence 4 Homologs of previously reported genes of
GJJ12_RS12505	COG4774	siderophore transport
GJJ12_RS12515	COG1619	proteins homologs of microcin C7 resistance protein MccF
GJJ12_RS12540	COG2719	SpoVR family
GJJ12_RS12570	COG0179	Fumarylacetoacetate (FAA) hydrolase
GJJ12_RS12585	COG2894	cell division
GJJ12_RS12595	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GJJ12_RS12605	COG3065	identical protein binding
GJJ12_RS12615	COG1199	ATP-dependent helicase activity
GJJ12_RS12620	COG0251	oxidation-reduction process
GJJ12_RS12640	COG1760	l-serine dehydratase
GJJ12_RS12645	COG2200	EAL domain
GJJ12_RS12650	COG1253	flavin adenine dinucleotide binding
GJJ12_RS12665	COG3715	PTS system
GJJ12_RS12670	COG3716	PTS system mannose fructose sorbose family IID component
GJJ12_RS12680	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJJ12_RS12680	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJJ12_RS12685	COG3715	PTS system
GJJ12_RS12690	COG3716	PTS system mannose fructose sorbose family IID component
GJJ12_RS12705	COG2226	methyltransferase
GJJ12_RS12710	COG0768	penicillin binding
GJJ12_RS12740	COG1414	Transcriptional regulator
GJJ12_RS12745	COG2814	Major facilitator Superfamily
GJJ12_RS12765	COG1956	GAF domain-containing protein
GJJ12_RS12770	COG2995	paraquat-inducible protein a
GJJ12_RS12775	COG3008	intermembrane lipid transfer
GJJ12_RS12800	COG2990	Protein conserved in bacteria
GJJ12_RS12815	COG1276	copper resistance
GJJ12_RS12820	COG2372	response to copper ion
GJJ12_RS12830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GJJ12_RS12835	COG1770	oligopeptidase
GJJ12_RS12840	COG2979	Protein of unknown function (DUF533)
GJJ12_RS12845	COG3141	response to X-ray
GJJ12_RS12855	COG0800	Aldolase
GJJ12_RS12860	COG0129	dihydroxy-acid dehydratase activity
GJJ12_RS12865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GJJ12_RS12875	COG1737	Transcriptional regulator
GJJ12_RS12885	COG1560	Kdo2-lipid A biosynthetic process
GJJ12_RS12890	COG0739	heme binding
GJJ12_RS12895	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GJJ12_RS12905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GJJ12_RS12930	COG0494	nUDIX hydrolase
GJJ12_RS12940	COG1335	isochorismatase
GJJ12_RS12945	COG1801	Protein of unknown function DUF72
GJJ12_RS12950	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GJJ12_RS12970	COG3102	Protein conserved in bacteria
GJJ12_RS12980	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GJJ12_RS13005	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS13015	COG1879	ABC-type sugar transport system periplasmic component
GJJ12_RS13025	COG1528	Iron-storage protein
GJJ12_RS13035	COG2211	Major facilitator Superfamily
GJJ12_RS13045	COG0477	Major facilitator Superfamily
GJJ12_RS13060	COG1528	Iron-storage protein
GJJ12_RS13070	COG0814	amino acid
GJJ12_RS13075	COG3318	Belongs to the UPF0149 family
GJJ12_RS13075	COG3012	SEC-C Motif Domain Protein
GJJ12_RS13110	COG2197	response regulator
GJJ12_RS13120	COG2197	response regulator
GJJ12_RS13125	COG1126	abc transporter atp-binding protein
GJJ12_RS13130	COG0765	amino acid transport
GJJ12_RS13140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJJ12_RS13145	COG0366	Alpha amylase catalytic
GJJ12_RS13175	COG2354	Protein conserved in bacteria
GJJ12_RS13180	COG0697	spore germination
GJJ12_RS13185	COG3727	T/G mismatch-specific endonuclease activity
GJJ12_RS13190	COG0270	DNA (cytosine-5-)-methyltransferase activity
GJJ12_RS13200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GJJ12_RS13250	COG0025	NhaP-type Na H and K H
GJJ12_RS13255	COG1309	transcriptional regulator
GJJ12_RS13260	COG0604	alcohol dehydrogenase
GJJ12_RS13280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GJJ12_RS13290	COG0534	Mate efflux family protein
GJJ12_RS13310	COG3706	GGDEF domain
GJJ12_RS13335	COG3615	Tellurite resistance protein tehB
GJJ12_RS13345	COG5001	Diguanylate cyclase
GJJ12_RS13345	COG3300	MHYT domain
GJJ12_RS13355	COG0477	Major facilitator Superfamily
GJJ12_RS13360	COG0095	Lipoate-protein ligase
GJJ12_RS13365	COG0583	DNA-binding transcription factor activity
GJJ12_RS13370	COG1942	4-Oxalocrotonate Tautomerase
GJJ12_RS13380	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GJJ12_RS13400	COG1289	transmembrane transporter activity
GJJ12_RS13415	COG2925	Exonuclease
GJJ12_RS13425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GJJ12_RS13430	COG0640	Transcriptional regulator
GJJ12_RS13435	COG0531	amino acid
GJJ12_RS13445	COG0583	DNA-binding transcription factor activity
GJJ12_RS13450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GJJ12_RS13480	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GJJ12_RS13505	COG0463	Glycosyl transferase, family 2
GJJ12_RS13515	COG1442	glycosyl transferase family 8
GJJ12_RS13515	COG1216	Glycosyl transferase, family 2
GJJ12_RS13520	COG0438	transferase activity, transferring glycosyl groups
GJJ12_RS13575	COG0628	permease
GJJ12_RS13605	COG0679	Auxin Efflux Carrier
GJJ12_RS13615	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GJJ12_RS13640	COG3290	protein histidine kinase activity
GJJ12_RS13645	COG4565	transcriptional regulatory protein
GJJ12_RS13665	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GJJ12_RS13665	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GJJ12_RS13675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GJJ12_RS13680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GJJ12_RS13690	COG0183	Belongs to the thiolase family
GJJ12_RS13695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GJJ12_RS13705	COG1414	Transcriptional regulator
GJJ12_RS13710	COG2840	Smr protein MutS2
GJJ12_RS13715	COG0583	DNA-binding transcription factor activity
GJJ12_RS13725	COG1473	amidohydrolase
GJJ12_RS13730	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GJJ12_RS13745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GJJ12_RS13760	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GJJ12_RS13765	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GJJ12_RS13780	COG0531	amino acid
GJJ12_RS13790	COG3136	membrane protein required for alginate biosynthesis
GJJ12_RS13795	COG0745	RESPONSE REGULATOR receiver
GJJ12_RS13805	COG2205	protein histidine kinase activity
GJJ12_RS13815	COG0114	fumarate hydratase activity
GJJ12_RS13820	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GJJ12_RS13820	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GJJ12_RS13825	COG1482	cell wall glycoprotein biosynthetic process
GJJ12_RS13830	COG5339	Protein conserved in bacteria
GJJ12_RS13835	COG1609	Transcriptional regulator
GJJ12_RS13840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJJ12_RS13840	COG1263	PTS System
GJJ12_RS13845	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GJJ12_RS13870	COG2391	methyltransferase activity
GJJ12_RS13875	COG0425	Belongs to the sulfur carrier protein TusA family
GJJ12_RS13880	COG5562	phage envelope protein
GJJ12_RS13885	COG0401	homolog of Blt101
GJJ12_RS13890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GJJ12_RS13895	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS13905	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GJJ12_RS13910	COG0477	Major facilitator Superfamily
GJJ12_RS13915	COG1113	amino acid transport
GJJ12_RS13920	COG2988	succinylglutamate desuccinylase activity
GJJ12_RS13925	COG3724	N-succinylarginine dihydrolase activity
GJJ12_RS13930	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS13935	COG3138	arginine N-succinyltransferase
GJJ12_RS13940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GJJ12_RS13950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GJJ12_RS13955	COG0667	Aldo Keto reductase
GJJ12_RS13960	COG0583	DNA-binding transcription factor activity
GJJ12_RS13985	COG4122	O-methyltransferase activity
GJJ12_RS13990	COG1643	Atp-dependent helicase
GJJ12_RS14005	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GJJ12_RS14010	COG3327	negative regulation of DNA-templated transcription, initiation
GJJ12_RS14015	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GJJ12_RS14020	COG0183	Belongs to the thiolase family
GJJ12_RS14025	COG2050	protein possibly involved in aromatic compounds catabolism
GJJ12_RS14030	COG1250	3-hydroxyacyl-CoA dehydrogenase
GJJ12_RS14035	COG1024	Enoyl-CoA hydratase
GJJ12_RS14040	COG1024	Enoyl-CoA hydratase
GJJ12_RS14045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GJJ12_RS14050	COG2151	metal-sulfur cluster biosynthetic enzyme
GJJ12_RS14055	COG3396	Phenylacetate-CoA oxygenase
GJJ12_RS14060	COG3460	Phenylacetate-CoA oxygenase
GJJ12_RS14065	COG3396	Phenylacetate-CoA oxygenase
GJJ12_RS14070	COG2030	dehydratase
GJJ12_RS14070	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS14090	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS14095	COG2207	Transcriptional regulator
GJJ12_RS14100	COG3784	Protein of unknown function (DUF1318)
GJJ12_RS14110	COG2911	Protein conserved in bacteria
GJJ12_RS14115	COG0586	Pfam SNARE associated Golgi protein
GJJ12_RS14120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GJJ12_RS14125	COG3187	Heat shock protein
GJJ12_RS14130	COG3042	response to heat
GJJ12_RS14135	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GJJ12_RS14135	COG0674	pyruvate-flavodoxin oxidoreductase activity
GJJ12_RS14135	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GJJ12_RS14135	COG1013	pyruvate-flavodoxin oxidoreductase activity
GJJ12_RS14140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GJJ12_RS14150	COG0589	response to stress
GJJ12_RS14160	COG0513	Belongs to the DEAD box helicase family
GJJ12_RS14170	COG1349	DNA-binding transcription factor activity
GJJ12_RS14175	COG0673	inositol 2-dehydrogenase activity
GJJ12_RS14190	COG1113	amino acid transport
GJJ12_RS14195	COG1522	sequence-specific DNA binding
GJJ12_RS14210	COG2011	ABC-type metal ion transport system permease component
GJJ12_RS14215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GJJ12_RS14225	COG0436	Aminotransferase
GJJ12_RS14230	COG0604	alcohol dehydrogenase
GJJ12_RS14260	COG0583	DNA-binding transcription factor activity
GJJ12_RS14280	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS14285	COG1309	transcriptional regulator
GJJ12_RS14290	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS14370	COG2885	chlorophyll binding
GJJ12_RS14605	COG0484	heat shock protein binding
GJJ12_RS14610	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GJJ12_RS14620	COG1484	DNA-dependent DNA replication
GJJ12_RS14700	COG0582	viral genome integration into host DNA
GJJ12_RS14705	COG0693	protein deglycase activity
GJJ12_RS14710	COG1078	dGTPase activity
GJJ12_RS14715	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS14720	COG0583	DNA-binding transcription factor activity
GJJ12_RS14740	COG0656	L-ascorbic acid biosynthetic process
GJJ12_RS14780	COG4166	transmembrane transport
GJJ12_RS14790	COG2866	Carboxypeptidase
GJJ12_RS14795	COG4948	Mandelate Racemase Muconate Lactonizing
GJJ12_RS14800	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GJJ12_RS14805	COG3180	Ammonia monooxygenase
GJJ12_RS14815	COG1486	melibiose metabolic process
GJJ12_RS14820	COG0583	DNA-binding transcription factor activity
GJJ12_RS14830	COG3106	COG3106 Predicted ATPase
GJJ12_RS14840	COG1983	PspC domain protein
GJJ12_RS14850	COG1842	Phage shock protein A
GJJ12_RS14855	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GJJ12_RS14865	COG1473	amidohydrolase
GJJ12_RS14880	COG0702	epimerase
GJJ12_RS14895	COG4171	peptide transport system, permease
GJJ12_RS14910	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GJJ12_RS14920	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GJJ12_RS14925	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GJJ12_RS14925	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GJJ12_RS14940	COG1349	DNA-binding transcription factor activity
GJJ12_RS14950	COG0023	Translation Initiation Factor
GJJ12_RS14960	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GJJ12_RS14965	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GJJ12_RS14970	COG0671	phosphoesterase, PA-phosphatase related
GJJ12_RS14980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GJJ12_RS15005	COG0616	signal peptide processing
GJJ12_RS15015	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS15020	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GJJ12_RS15030	COG0583	DNA-binding transcription factor activity
GJJ12_RS15040	COG0009	L-threonylcarbamoyladenylate synthase
GJJ12_RS15050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GJJ12_RS15055	COG0512	Glutamine amidotransferase of anthranilate synthase
GJJ12_RS15055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GJJ12_RS15060	COG0135	phosphoribosylanthranilate isomerase activity
GJJ12_RS15060	COG0134	indole-3-glycerol-phosphate synthase activity
GJJ12_RS15115	COG4774	siderophore transport
GJJ12_RS15125	COG3047	cAMP biosynthetic process
GJJ12_RS15130	COG0727	PFAM Uncharacterised protein family (UPF0153)
GJJ12_RS15160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GJJ12_RS15165	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS15170	COG1988	membrane-bound metal-dependent
GJJ12_RS15175	COG1823	symporter activity
GJJ12_RS15185	COG0753	catalase activity
GJJ12_RS15195	COG1486	melibiose metabolic process
GJJ12_RS15200	COG1917	Cupin 2, conserved barrel domain protein
GJJ12_RS15200	COG2169	Transcriptional regulator
GJJ12_RS15205	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJJ12_RS15210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJJ12_RS15220	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJJ12_RS15225	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GJJ12_RS15235	COG0322	excinuclease ABC activity
GJJ12_RS15240	COG3678	ATP-independent chaperone mediated protein folding
GJJ12_RS15250	COG3724	N-succinylarginine dihydrolase activity
GJJ12_RS15260	COG3138	arginine N-succinyltransferase
GJJ12_RS15270	COG0708	Exodeoxyribonuclease III
GJJ12_RS15275	COG0398	Pfam SNARE associated Golgi protein
GJJ12_RS15280	COG0398	Pfam SNARE associated Golgi protein
GJJ12_RS15285	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GJJ12_RS15290	COG4134	Bacterial extracellular solute-binding protein
GJJ12_RS15295	COG4135	transport system, permease component
GJJ12_RS15300	COG4136	ATPase activity
GJJ12_RS15305	COG2897	thiosulfate sulfurtransferase activity
GJJ12_RS15310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GJJ12_RS15315	COG0494	nUDIX hydrolase
GJJ12_RS15320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GJJ12_RS15325	COG0604	alcohol dehydrogenase
GJJ12_RS15325	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS15325	COG3321	synthase
GJJ12_RS15330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GJJ12_RS15335	COG0709	Synthesizes selenophosphate from selenide and ATP
GJJ12_RS15345	COG0778	Nitroreductase
GJJ12_RS15350	COG0616	signal peptide processing
GJJ12_RS15355	COG0252	asparaginase activity
GJJ12_RS15360	COG1335	isochorismatase
GJJ12_RS15375	COG3139	Protein of unknown function (DUF1315)
GJJ12_RS15395	COG0656	L-ascorbic acid biosynthetic process
GJJ12_RS15400	COG3713	MltA-interacting MipA family protein
GJJ12_RS15405	COG2766	serine protein kinase
GJJ12_RS15420	COG0386	Belongs to the glutathione peroxidase family
GJJ12_RS15445	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS15450	COG0583	DNA-binding transcription factor activity
GJJ12_RS15455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GJJ12_RS15460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GJJ12_RS15465	COG3344	reverse transcriptase
GJJ12_RS15475	COG0859	PFAM glycosyl transferase family 9
GJJ12_RS15480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GJJ12_RS15490	COG2207	Transcriptional regulator
GJJ12_RS15495	COG2807	transmembrane transport
GJJ12_RS15500	COG0504	CTP synthase activity
GJJ12_RS15505	COG1683	Conserved Protein
GJJ12_RS15510	COG3189	MarR family transcriptional regulator
GJJ12_RS15515	COG3042	response to heat
GJJ12_RS15525	COG2199	diguanylate cyclase activity
GJJ12_RS15525	COG2203	Gaf domain
GJJ12_RS15545	COG3182	Iron-regulated membrane protein
GJJ12_RS15555	COG1560	Kdo2-lipid A biosynthetic process
GJJ12_RS15565	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GJJ12_RS15570	COG3706	GGDEF domain
GJJ12_RS15575	COG0583	DNA-binding transcription factor activity
GJJ12_RS15580	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GJJ12_RS15605	COG1294	oxidase, subunit
GJJ12_RS15610	COG1271	oxidase subunit
GJJ12_RS15615	COG3546	catalase activity
GJJ12_RS15620	COG3685	Protein conserved in bacteria
GJJ12_RS15625	COG3685	Protein conserved in bacteria
GJJ12_RS15630	COG3729	General stress protein
GJJ12_RS15635	COG3039	Transposase
GJJ12_RS15640	COG1063	alcohol dehydrogenase
GJJ12_RS15645	COG3813	Protein conserved in bacteria
GJJ12_RS15665	COG0640	Transcriptional regulator
GJJ12_RS15670	COG0538	isocitrate dehydrogenase activity
GJJ12_RS15675	COG1187	pseudouridine synthase activity
GJJ12_RS15695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GJJ12_RS15715	COG2205	protein histidine kinase activity
GJJ12_RS15720	COG2850	peptidyl-arginine hydroxylation
GJJ12_RS15725	COG1943	Transposase
GJJ12_RS15745	COG1177	transmembrane transport
GJJ12_RS15760	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GJJ12_RS15770	COG0318	PFAM AMP-dependent synthetase and ligase
GJJ12_RS15780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GJJ12_RS15790	COG4591	ABC-type transport system involved in lipoprotein release permease component
GJJ12_RS15800	COG4591	ABC-type transport system involved in lipoprotein release permease component
GJJ12_RS15810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GJJ12_RS15815	COG1388	LysM domain
GJJ12_RS15815	COG1376	ErfK ybiS ycfS ynhG family protein
GJJ12_RS15830	COG1309	transcriptional regulator
GJJ12_RS15845	COG3134	Outer membrane lipoprotein
GJJ12_RS15850	COG1252	NADH dehydrogenase
GJJ12_RS15875	COG5633	Lipoprotein
GJJ12_RS15880	COG0537	adenosine 5'-monophosphoramidase activity
GJJ12_RS15890	COG0084	hydrolase, TatD family'
GJJ12_RS15895	COG0470	DNA polymerase III
GJJ12_RS15905	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GJJ12_RS15910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GJJ12_RS15915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GJJ12_RS15930	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GJJ12_RS15950	COG1399	metal-binding, possibly nucleic acid-binding protein
GJJ12_RS15970	COG1530	ribonuclease E activity
GJJ12_RS15975	COG0583	DNA-binding transcription factor activity
GJJ12_RS15980	COG2814	Major facilitator Superfamily
GJJ12_RS16000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GJJ12_RS16050	COG1560	Kdo2-lipid A biosynthetic process
GJJ12_RS16065	COG5645	(Lipo)protein
GJJ12_RS16100	COG3381	protein complex oligomerization
GJJ12_RS16120	COG0583	DNA-binding transcription factor activity
GJJ12_RS16130	COG1335	isochorismatase
GJJ12_RS16140	COG1702	phosphate starvation-inducible protein PhoH
GJJ12_RS16160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GJJ12_RS16170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GJJ12_RS16185	COG1309	transcriptional regulator
GJJ12_RS16220	COG2233	PERMEase
GJJ12_RS16230	COG3729	General stress protein
GJJ12_RS16260	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS16275	COG0531	amino acid
GJJ12_RS16280	COG0174	glutamine synthetase
GJJ12_RS16285	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GJJ12_RS16290	COG1917	Cupin 2, conserved barrel domain protein
GJJ12_RS16290	COG1396	sequence-specific DNA binding
GJJ12_RS16295	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS16300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GJJ12_RS16305	COG0583	DNA-binding transcription factor activity
GJJ12_RS16310	COG0473	3-isopropylmalate dehydrogenase activity
GJJ12_RS16315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GJJ12_RS16320	COG4638	Rieske (2fe-2S)
GJJ12_RS16325	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS16330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GJJ12_RS16355	COG0670	Belongs to the BI1 family
GJJ12_RS16370	COG2207	Transcriptional regulator
GJJ12_RS16375	COG1881	PFAM PEBP family protein
GJJ12_RS16390	COG1832	CoA-binding protein
GJJ12_RS16400	COG0210	DNA helicase
GJJ12_RS16405	COG3304	Inner membrane component domain
GJJ12_RS16410	COG1289	transmembrane transporter activity
GJJ12_RS16415	COG3070	regulator of competence-specific genes
GJJ12_RS16435	COG1067	ATP-dependent peptidase activity
GJJ12_RS16445	COG3130	regulation of translation
GJJ12_RS16450	COG3009	Protein conserved in bacteria
GJJ12_RS16455	COG3008	intermembrane lipid transfer
GJJ12_RS16455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GJJ12_RS16460	COG2995	paraquat-inducible protein a
GJJ12_RS16465	COG0488	(ABC) transporter
GJJ12_RS16475	COG0633	Ferredoxin
GJJ12_RS16475	COG3217	Mosc domain protein beta barrel domain protein
GJJ12_RS16490	COG0431	NADPH-dependent FMN reductase
GJJ12_RS16495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GJJ12_RS16500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GJJ12_RS16505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GJJ12_RS16515	COG0308	aminopeptidase N
GJJ12_RS16525	COG1473	amidohydrolase
GJJ12_RS16535	COG0814	amino acid
GJJ12_RS16555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GJJ12_RS16560	COG1448	Aminotransferase
GJJ12_RS16565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GJJ12_RS16570	COG3108	Peptidase M15
GJJ12_RS16575	COG2989	Protein conserved in bacteria
GJJ12_RS16585	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GJJ12_RS16595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GJJ12_RS16600	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GJJ12_RS16605	COG3173	Aminoglycoside phosphotransferase
GJJ12_RS16620	COG3214	Protein conserved in bacteria
GJJ12_RS16635	COG0658	competence protein
GJJ12_RS16635	COG2333	competence protein COMEC
GJJ12_RS16645	COG0539	negative regulation of cytoplasmic translation
GJJ12_RS16665	COG2323	membrane
GJJ12_RS16670	COG1944	ATP diphosphatase activity
GJJ12_RS16675	COG2116	formate transmembrane transporter activity
GJJ12_RS16680	COG1882	Formate acetyltransferase
GJJ12_RS16685	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GJJ12_RS16690	COG0477	Major facilitator Superfamily
GJJ12_RS16695	COG3302	dmso reductase anchor subunit
GJJ12_RS16700	COG0437	4 iron, 4 sulfur cluster binding
GJJ12_RS16705	COG0243	molybdopterin cofactor binding
GJJ12_RS16715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GJJ12_RS16725	COG1178	ABC-type Fe3 transport system permease component
GJJ12_RS16725	COG1674	ftsk spoiiie
GJJ12_RS16735	COG0492	ferredoxin-NADP+ reductase activity
GJJ12_RS16740	COG4988	ABC transporter
GJJ12_RS16745	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GJJ12_RS16760	COG0542	response to heat
GJJ12_RS16770	COG1278	Cold shock
GJJ12_RS16780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJJ12_RS16785	COG3593	DNA synthesis involved in DNA repair
GJJ12_RS16805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GJJ12_RS16815	COG0028	Belongs to the TPP enzyme family
GJJ12_RS16820	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GJJ12_RS16825	COG0702	epimerase
GJJ12_RS16830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GJJ12_RS16835	COG3023	N-Acetylmuramoyl-L-alanine amidase
GJJ12_RS16840	COG2203	Gaf domain
GJJ12_RS16840	COG3706	GGDEF domain
GJJ12_RS16840	COG4251	negative regulation of phosphorylation
GJJ12_RS16840	COG5001	Diguanylate cyclase
GJJ12_RS16850	COG1126	abc transporter atp-binding protein
GJJ12_RS16855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJJ12_RS16860	COG4215	(ABC) transporter
GJJ12_RS16865	COG4160	amino acid transport
GJJ12_RS16870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJJ12_RS16875	COG5002	protein histidine kinase activity
GJJ12_RS16880	COG0745	RESPONSE REGULATOR receiver
GJJ12_RS16885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GJJ12_RS16895	COG1177	transmembrane transport
GJJ12_RS16900	COG1176	ABC-type spermidine putrescine transport system, permease component I
GJJ12_RS16905	COG3842	ATPase activity
GJJ12_RS16910	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GJJ12_RS16925	COG0778	Nitroreductase
GJJ12_RS16950	COG3226	Transcriptional regulator
GJJ12_RS16955	COG0738	Major facilitator superfamily
GJJ12_RS16960	COG0561	phosphatase activity
GJJ12_RS16965	COG2814	Major facilitator Superfamily
GJJ12_RS16970	COG0671	phosphoesterase, PA-phosphatase related
GJJ12_RS16975	COG1349	DNA-binding transcription factor activity
GJJ12_RS16980	COG1686	Belongs to the peptidase S11 family
GJJ12_RS16990	COG0625	glutathione transferase activity
GJJ12_RS16995	COG2133	pyrroloquinoline quinone binding
GJJ12_RS17005	COG2223	nitrite transmembrane transporter activity
GJJ12_RS17025	COG0747	negative chemotaxis
GJJ12_RS17040	COG0303	'Molybdopterin
GJJ12_RS17045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GJJ12_RS17050	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GJJ12_RS17055	COG1882	Formate acetyltransferase
GJJ12_RS17060	COG0561	phosphatase activity
GJJ12_RS17070	COG1609	Transcriptional regulator
GJJ12_RS17075	COG2271	Major facilitator Superfamily
GJJ12_RS17085	COG0488	(ABC) transporter
GJJ12_RS17090	COG2365	Tyrosine phosphatase family
GJJ12_RS17095	COG1376	ErfK ybiS ycfS ynhG family protein
GJJ12_RS17100	COG2188	Transcriptional regulator
GJJ12_RS17105	COG2723	6-phospho-beta-galactosidase activity
GJJ12_RS17110	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GJJ12_RS17125	COG2194	sulfuric ester hydrolase activity
GJJ12_RS17130	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GJJ12_RS17145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJJ12_RS17150	COG0765	amino acid transport
GJJ12_RS17155	COG1126	abc transporter atp-binding protein
GJJ12_RS17160	COG0668	transmembrane transport
GJJ12_RS17170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GJJ12_RS17180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GJJ12_RS17190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GJJ12_RS17195	COG1199	ATP-dependent helicase activity
GJJ12_RS17200	COG0513	Belongs to the DEAD box helicase family
GJJ12_RS17205	COG3958	Transketolase
GJJ12_RS17210	COG3959	Transketolase, thiamine diphosphate binding domain
GJJ12_RS17215	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS17220	COG2271	Major facilitator Superfamily
GJJ12_RS17230	COG0583	DNA-binding transcription factor activity
GJJ12_RS17235	COG1309	transcriptional regulator
GJJ12_RS17240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJJ12_RS17245	COG1131	(ABC) transporter
GJJ12_RS17250	COG0842	Transport permease protein
GJJ12_RS17255	COG0842	Transport permease protein
GJJ12_RS17265	COG3568	Endonuclease Exonuclease Phosphatase
GJJ12_RS17270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GJJ12_RS17275	COG0392	lysyltransferase activity
GJJ12_RS17280	COG0670	Belongs to the BI1 family
GJJ12_RS17285	COG0314	molybdopterin synthase activity
GJJ12_RS17290	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GJJ12_RS17300	COG0521	Mo-molybdopterin cofactor biosynthetic process
GJJ12_RS17320	COG0745	RESPONSE REGULATOR receiver
GJJ12_RS17325	COG0642	Histidine kinase
GJJ12_RS17350	COG2226	methyltransferase
GJJ12_RS17365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GJJ12_RS17370	COG1881	PFAM PEBP family protein
GJJ12_RS17410	COG4677	pectinesterase activity
GJJ12_RS17420	COG0589	response to stress
GJJ12_RS17425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJJ12_RS17460	COG0789	Transcriptional regulator
GJJ12_RS17465	COG2200	EAL domain
GJJ12_RS17490	COG0561	phosphatase activity
GJJ12_RS17500	COG4149	molybdate abc transporter
GJJ12_RS17505	COG0725	ABC transporter, periplasmic molybdate-binding protein
GJJ12_RS17515	COG2005	Transcriptional regulator
GJJ12_RS17515	COG3585	molybdate ion transport
GJJ12_RS17520	COG1119	ATPase activity
GJJ12_RS17530	COG1085	galactose-1-phosphate uridylyltransferase
GJJ12_RS17540	COG2017	converts alpha-aldose to the beta-anomer
GJJ12_RS17550	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GJJ12_RS17565	COG3201	nicotinamide mononucleotide transporter
GJJ12_RS17570	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GJJ12_RS17615	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GJJ12_RS17620	COG2885	chlorophyll binding
GJJ12_RS17630	COG3064	Membrane
GJJ12_RS17635	COG0848	biopolymer transport protein
GJJ12_RS17640	COG0811	peptide transport
GJJ12_RS17645	COG0824	Thioesterase
GJJ12_RS17650	COG3790	cyd operon protein YbgE
GJJ12_RS17655	COG4890	Cyd operon protein YbgT
GJJ12_RS17660	COG1294	oxidase, subunit
GJJ12_RS17665	COG1271	oxidase subunit
GJJ12_RS17670	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GJJ12_RS17680	COG0508	dehydrogenase complex catalyzes the overall conversion of
GJJ12_RS17685	COG0567	Dehydrogenase, E1 component
GJJ12_RS17690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GJJ12_RS17695	COG1053	succinate dehydrogenase
GJJ12_RS17700	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GJJ12_RS17705	COG2009	succinate dehydrogenase
GJJ12_RS17740	COG1984	allophanate hydrolase subunit 2
GJJ12_RS17745	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GJJ12_RS17760	COG0415	Belongs to the DNA photolyase family
GJJ12_RS17790	COG2205	protein histidine kinase activity
GJJ12_RS17795	COG0745	RESPONSE REGULATOR receiver
GJJ12_RS17805	COG0033	Phosphoglucomutase
GJJ12_RS17815	COG0596	Alpha beta hydrolase
GJJ12_RS17830	COG0735	belongs to the Fur family
GJJ12_RS17870	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GJJ12_RS17875	COG1846	Transcriptional regulator
GJJ12_RS17875	COG1940	carbohydrate kinase activity
GJJ12_RS17880	COG0647	UMP catabolic process
GJJ12_RS17885	COG0367	asparagine synthase
GJJ12_RS17920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GJJ12_RS17930	COG1702	phosphate starvation-inducible protein PhoH
GJJ12_RS17955	COG0765	amino acid transport
GJJ12_RS17960	COG0765	amino acid transport
GJJ12_RS17965	COG1126	abc transporter atp-binding protein
GJJ12_RS17980	COG2888	peptidyl-tyrosine sulfation
GJJ12_RS17995	COG1466	dna polymerase III delta subunit
GJJ12_RS18010	COG0799	negative regulation of ribosome biogenesis
GJJ12_RS18020	COG0768	penicillin binding
GJJ12_RS18025	COG0772	Belongs to the SEDS family
GJJ12_RS18030	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GJJ12_RS18035	COG1686	Belongs to the peptidase S11 family
GJJ12_RS18050	COG0583	DNA-binding transcription factor activity
GJJ12_RS18065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GJJ12_RS18085	COG3069	C4-dicarboxylate transmembrane transporter activity
GJJ12_RS18090	COG3719	Belongs to the RNase T2 family
GJJ12_RS18095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GJJ12_RS18115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GJJ12_RS18120	COG0583	DNA-binding transcription factor activity
GJJ12_RS18125	COG3969	phosphoadenosine phosphosulfate
GJJ12_RS18130	COG1475	DNA binding
GJJ12_RS18135	COG0436	Aminotransferase
GJJ12_RS18160	COG1129	ABC transporter
GJJ12_RS18165	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS18170	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS18180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GJJ12_RS18195	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GJJ12_RS18205	COG0402	S-adenosylhomocysteine deaminase activity
GJJ12_RS18215	COG0483	inositol monophosphate 1-phosphatase activity
GJJ12_RS18250	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS18255	COG1129	ABC transporter
GJJ12_RS18260	COG0371	Dehydrogenase
GJJ12_RS18265	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS18280	COG2879	small protein
GJJ12_RS18285	COG1966	Carbon starvation protein
GJJ12_RS18295	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS18300	COG1535	isochorismatase
GJJ12_RS18300	COG3433	isochorismatase activity
GJJ12_RS18305	COG1021	2,3-dihydroxybenzoate-AMP ligase
GJJ12_RS18310	COG1169	isochorismate synthase
GJJ12_RS18315	COG4592	Periplasmic binding protein
GJJ12_RS18325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJJ12_RS18330	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJJ12_RS18335	COG1120	ATPase activity
GJJ12_RS18340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GJJ12_RS18340	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GJJ12_RS18345	COG3251	PFAM MbtH domain protein
GJJ12_RS18350	COG2382	esterase
GJJ12_RS18355	COG4771	TonB-dependent receptor
GJJ12_RS18360	COG2977	Belongs to the P-Pant transferase superfamily
GJJ12_RS18365	COG3958	Transketolase
GJJ12_RS18370	COG3959	Transketolase, thiamine diphosphate binding domain
GJJ12_RS18375	COG2390	Transcriptional regulator
GJJ12_RS18380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GJJ12_RS18385	COG1879	ABC-type sugar transport system periplasmic component
GJJ12_RS18395	COG1129	ABC transporter
GJJ12_RS18400	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS18420	COG0583	DNA-binding transcription factor activity
GJJ12_RS18425	COG0668	transmembrane transport
GJJ12_RS18435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GJJ12_RS18460	COG0747	negative chemotaxis
GJJ12_RS18465	COG0601	transmembrane transport
GJJ12_RS18470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJJ12_RS18475	COG0444	Belongs to the ABC transporter superfamily
GJJ12_RS18480	COG4608	Belongs to the ABC transporter superfamily
GJJ12_RS18485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GJJ12_RS18490	COG4221	oxidoreductase activity
GJJ12_RS18500	COG4215	(ABC) transporter
GJJ12_RS18505	COG0765	amino acid transport
GJJ12_RS18510	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GJJ12_RS18525	COG0697	spore germination
GJJ12_RS18540	COG4608	Belongs to the ABC transporter superfamily
GJJ12_RS18545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJJ12_RS18555	COG4166	transmembrane transport
GJJ12_RS18565	COG3698	Phosphodiester glycosidase
GJJ12_RS18605	COG2315	Protein conserved in bacteria
GJJ12_RS18610	COG0778	Nitroreductase
GJJ12_RS18635	COG0477	Major facilitator Superfamily
GJJ12_RS18640	COG0668	transmembrane transport
GJJ12_RS18645	COG1609	Transcriptional regulator
GJJ12_RS18655	COG0673	inositol 2-dehydrogenase activity
GJJ12_RS18665	COG2211	Major facilitator Superfamily
GJJ12_RS18670	COG1113	amino acid transport
GJJ12_RS18685	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS18690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GJJ12_RS18700	COG0531	amino acid
GJJ12_RS18745	COG0667	Aldo Keto reductase
GJJ12_RS18750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJJ12_RS18755	COG1473	amidohydrolase
GJJ12_RS18785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJJ12_RS18790	COG1120	ATPase activity
GJJ12_RS18795	COG1566	PFAM secretion protein HlyD family protein
GJJ12_RS18840	COG4211	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS18845	COG1129	ABC transporter
GJJ12_RS18860	COG0673	inositol 2-dehydrogenase activity
GJJ12_RS18890	COG3104	oligopeptide transport
GJJ12_RS18895	COG1982	Orn Lys Arg decarboxylase major
GJJ12_RS18900	COG0531	amino acid
GJJ12_RS18905	COG3710	Transcriptional regulator
GJJ12_RS18915	COG1560	Kdo2-lipid A biosynthetic process
GJJ12_RS18930	COG3188	usher protein
GJJ12_RS18935	COG3121	Chaperone
GJJ12_RS18940	COG3539	Fimbrial protein
GJJ12_RS19040	COG1196	nuclear chromosome segregation
GJJ12_RS19040	COG0741	lytic transglycosylase activity
GJJ12_RS19040	COG0739	heme binding
GJJ12_RS19120	COG5410	chromosome segregation
GJJ12_RS19140	COG3772	lysozyme
GJJ12_RS19285	COG3723	Recombinational DNA repair protein, rece pathway
GJJ12_RS19340	COG2501	S4 domain
GJJ12_RS19350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GJJ12_RS19365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GJJ12_RS19370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GJJ12_RS19390	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GJJ12_RS19395	COG4181	ATPase activity
GJJ12_RS19400	COG2755	lipolytic protein G-D-S-L family
GJJ12_RS19405	COG0300	oxidoreductase activity
GJJ12_RS19410	COG3118	belongs to the thioredoxin family
GJJ12_RS19415	COG0390	transport system, permease component
GJJ12_RS19420	COG4619	ABC transporter
GJJ12_RS19425	COG0330	HflC and HflK could
GJJ12_RS19430	COG1585	Membrane protein implicated in regulation of membrane protease activity
GJJ12_RS19445	COG3735	TraB family
GJJ12_RS19450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GJJ12_RS19460	COG2223	nitrite transmembrane transporter activity
GJJ12_RS19465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GJJ12_RS19465	COG4651	solute:proton antiporter activity
GJJ12_RS19470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GJJ12_RS19510	COG2832	Protein of unknown function (DUF454)
GJJ12_RS19515	COG3923	Primosomal replication protein n
GJJ12_RS19530	COG1196	nuclear chromosome segregation
GJJ12_RS19530	COG3264	Mechanosensitive ion channel
GJJ12_RS19535	COG1309	transcriptional regulator
GJJ12_RS19540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJJ12_RS19545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GJJ12_RS19560	COG0110	maltose O-acetyltransferase activity
GJJ12_RS19610	COG1874	Beta-galactosidase
GJJ12_RS19615	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GJJ12_RS19620	COG3833	ABC-type maltose transport systems, permease component
GJJ12_RS19625	COG1175	transmembrane transport
GJJ12_RS19630	COG2182	Extracellular solute-binding protein
GJJ12_RS19640	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GJJ12_RS19655	COG2364	Membrane
GJJ12_RS19685	COG3695	enzyme binding
GJJ12_RS19690	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GJJ12_RS19695	COG1946	Acyl-CoA thioesterase
GJJ12_RS19700	COG0004	ammonium transporteR
GJJ12_RS19705	COG0347	Belongs to the P(II) protein family
GJJ12_RS19710	COG1132	(ABC) transporter
GJJ12_RS19715	COG1132	(ABC) transporter
GJJ12_RS19720	COG1522	sequence-specific DNA binding
GJJ12_RS19735	COG4533	DNA binding
GJJ12_RS19745	COG0824	Thioesterase
GJJ12_RS19750	COG1555	photosystem II stabilization
GJJ12_RS19755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GJJ12_RS19760	COG0776	regulation of translation
GJJ12_RS19765	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GJJ12_RS19785	COG0271	Belongs to the BolA IbaG family
GJJ12_RS19790	COG3056	Lipoprotein
GJJ12_RS19795	COG2223	nitrite transmembrane transporter activity
GJJ12_RS19800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GJJ12_RS19805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GJJ12_RS19810	COG1845	cytochrome c oxidase, subunit III
GJJ12_RS19815	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GJJ12_RS19830	COG1414	Transcriptional regulator
GJJ12_RS19835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GJJ12_RS19840	COG1053	succinate dehydrogenase
GJJ12_RS19850	COG1053	succinate dehydrogenase
GJJ12_RS19865	COG0673	inositol 2-dehydrogenase activity
GJJ12_RS19870	COG2814	Major facilitator Superfamily
GJJ12_RS19880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GJJ12_RS19905	COG0142	geranyltranstransferase activity
GJJ12_RS19915	COG0667	Aldo Keto reductase
GJJ12_RS19920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GJJ12_RS19925	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GJJ12_RS19940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GJJ12_RS19940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GJJ12_RS19950	COG4238	major outer membrane lipoprotein
GJJ12_RS19970	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GJJ12_RS19975	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GJJ12_RS19980	COG1862	Preprotein translocase
GJJ12_RS20005	COG0450	alkyl hydroperoxide reductase
GJJ12_RS20015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJJ12_RS20030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GJJ12_RS20040	COG1228	amidohydrolase
GJJ12_RS20050	COG1335	isochorismatase
GJJ12_RS20055	COG0583	DNA-binding transcription factor activity
GJJ12_RS20095	COG0420	3'-5' exonuclease activity
GJJ12_RS20100	COG0419	ATPase involved in DNA repair
GJJ12_RS20105	COG1940	carbohydrate kinase activity
GJJ12_RS20120	COG4126	flavin adenine dinucleotide binding
GJJ12_RS20130	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GJJ12_RS20135	COG3416	Protein conserved in bacteria
GJJ12_RS20145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GJJ12_RS20155	COG1785	Belongs to the alkaline phosphatase family
GJJ12_RS20195	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GJJ12_RS20200	COG1335	isochorismatase
GJJ12_RS20205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GJJ12_RS20210	COG0113	porphobilinogen synthase activity
GJJ12_RS20220	COG2175	clavaminate synthase activity
GJJ12_RS20230	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GJJ12_RS20235	COG4521	taurine ABC transporter
GJJ12_RS20240	COG2040	homocysteine
GJJ12_RS20245	COG0833	amino acid
GJJ12_RS20260	COG4303	Ethanolamine ammonia lyase large subunit
GJJ12_RS20265	COG4302	ethanolamine ammonia-lyase activity
GJJ12_RS20305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJJ12_RS20310	COG1126	abc transporter atp-binding protein
GJJ12_RS20315	COG4597	amino acid ABC transporter
GJJ12_RS20320	COG0765	amino acid transport
GJJ12_RS20335	COG3188	usher protein
GJJ12_RS20360	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GJJ12_RS20370	COG3639	organic phosphonate transmembrane transporter activity
GJJ12_RS20390	COG0791	NLP P60 protein
GJJ12_RS20425	COG0582	viral genome integration into host DNA
GJJ12_RS20530	COG0582	viral genome integration into host DNA
GJJ12_RS20625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GJJ12_RS20630	COG0022	dehydrogenase e1 component
GJJ12_RS20635	COG0508	dehydrogenase complex catalyzes the overall conversion of
GJJ12_RS20640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJJ12_RS20650	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GJJ12_RS20665	COG0579	oxidoreductase
GJJ12_RS20670	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS20675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GJJ12_RS20680	COG1113	amino acid transport
GJJ12_RS20685	COG1802	Transcriptional regulator
GJJ12_RS20705	COG2195	Cleaves the N-terminal amino acid of tripeptides
GJJ12_RS20710	COG0454	-acetyltransferase
GJJ12_RS20725	COG2991	Protein conserved in bacteria
GJJ12_RS20740	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GJJ12_RS20745	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GJJ12_RS20760	COG3034	peptidoglycan biosynthetic process
GJJ12_RS20765	COG0121	glutamine amidotransferase
GJJ12_RS20775	COG1960	acyl-CoA dehydrogenase activity
GJJ12_RS20780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GJJ12_RS20790	COG0583	DNA-binding transcription factor activity
GJJ12_RS20800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GJJ12_RS20810	COG2226	methyltransferase
GJJ12_RS20820	COG0741	lytic transglycosylase activity
GJJ12_RS20820	COG1388	LysM domain
GJJ12_RS20825	COG2226	methyltransferase
GJJ12_RS20835	COG2814	Major facilitator Superfamily
GJJ12_RS20840	COG0583	DNA-binding transcription factor activity
GJJ12_RS20845	COG0656	L-ascorbic acid biosynthetic process
GJJ12_RS20880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GJJ12_RS20890	COG2011	ABC-type metal ion transport system permease component
GJJ12_RS20895	COG1464	Belongs to the NlpA lipoprotein family
GJJ12_RS20905	COG1720	tRNA m6t6A37 methyltransferase activity
GJJ12_RS20915	COG0791	NLP P60 protein
GJJ12_RS20920	COG3015	lipoprotein NlpE involved in copper resistance
GJJ12_RS20925	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GJJ12_RS20940	COG4568	rho-dependent transcription termination
GJJ12_RS20950	COG0346	lactoylglutathione lyase activity
GJJ12_RS20955	COG1982	Orn Lys Arg decarboxylase major
GJJ12_RS20965	COG0587	DNA-directed DNA polymerase activity
GJJ12_RS20995	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GJJ12_RS21005	COG0750	zinc metalloprotease
GJJ12_RS21010	COG0575	Belongs to the CDS family
GJJ12_RS21020	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GJJ12_RS21045	COG0024	Methionine aminopeptidase
GJJ12_RS21050	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GJJ12_RS21065	COG3835	regulator
GJJ12_RS21070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GJJ12_RS21090	COG2860	membrane
GJJ12_RS21110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJJ12_RS21115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GJJ12_RS21120	COG1120	ATPase activity
GJJ12_RS21125	COG4774	siderophore transport
GJJ12_RS21130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJJ12_RS21225	COG1643	Atp-dependent helicase
GJJ12_RS21230	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GJJ12_RS21250	COG0617	tRNA 3'-terminal CCA addition
GJJ12_RS21255	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GJJ12_RS21275	COG0726	polysaccharide deacetylase
GJJ12_RS21280	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJJ12_RS21285	COG0842	Transport permease protein
GJJ12_RS21290	COG1131	(ABC) transporter
GJJ12_RS21295	COG0288	reversible hydration of carbon dioxide
GJJ12_RS21310	COG4993	Dehydrogenase
GJJ12_RS21315	COG2132	Multicopper oxidase
GJJ12_RS21360	COG3064	Membrane
GJJ12_RS21375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJJ12_RS21380	COG0508	dehydrogenase complex catalyzes the overall conversion of
GJJ12_RS21385	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GJJ12_RS21390	COG2186	Transcriptional regulator
GJJ12_RS21395	COG1113	amino acid transport
GJJ12_RS21400	COG2211	Major facilitator Superfamily
GJJ12_RS21405	COG3940	Belongs to the glycosyl hydrolase 43 family
GJJ12_RS21410	COG3725	Membrane protein required for beta-lactamase induction
GJJ12_RS21415	COG3023	N-Acetylmuramoyl-L-alanine amidase
GJJ12_RS21425	COG4969	Belongs to the N-Me-Phe pilin family
GJJ12_RS21430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GJJ12_RS21435	COG1459	type II secretion system
GJJ12_RS21460	COG0494	nUDIX hydrolase
GJJ12_RS21480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GJJ12_RS21485	COG0849	cell division
GJJ12_RS21510	COG0772	Belongs to the SEDS family
GJJ12_RS21525	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GJJ12_RS21530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GJJ12_RS21535	COG0768	penicillin binding
GJJ12_RS21555	COG1609	Transcriptional regulator
GJJ12_RS21565	COG0028	Belongs to the TPP enzyme family
GJJ12_RS21610	COG0738	Major facilitator superfamily
GJJ12_RS21620	COG0583	DNA-binding transcription factor activity
GJJ12_RS21625	COG2271	Major facilitator Superfamily
GJJ12_RS21630	COG2814	Major facilitator Superfamily
GJJ12_RS21650	COG1178	ABC-type Fe3 transport system permease component
GJJ12_RS21660	COG0586	Pfam SNARE associated Golgi protein
GJJ12_RS21680	COG0235	Class ii aldolase
GJJ12_RS21685	COG0417	DNA replication proofreading
GJJ12_RS21695	COG0564	pseudouridine synthase activity
GJJ12_RS21705	COG3493	citrate carrier protein
GJJ12_RS21720	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GJJ12_RS21725	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GJJ12_RS21735	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GJJ12_RS21780	COG0505	Belongs to the CarA family
GJJ12_RS21845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GJJ12_RS21870	COG1047	Peptidyl-prolyl cis-trans
GJJ12_RS21885	COG0196	riboflavin kinase activity
GJJ12_RS21895	COG0583	DNA-binding transcription factor activity
GJJ12_RS21920	COG4735	regulation of single-species biofilm formation
GJJ12_RS21925	COG1584	GPR1 FUN34 yaaH family protein
GJJ12_RS21930	COG0477	Major facilitator Superfamily
GJJ12_RS21935	COG0521	Mo-molybdopterin cofactor biosynthetic process
GJJ12_RS21940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GJJ12_RS21945	COG1115	amino acid carrier protein
GJJ12_RS21955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GJJ12_RS21965	COG0460	homoserine dehydrogenase
GJJ12_RS21965	COG0527	aspartate kinase activity
GJJ12_RS21975	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GJJ12_RS21985	COG0745	RESPONSE REGULATOR receiver
GJJ12_RS21990	COG4452	Inner membrane protein CreD
GJJ12_RS21995	COG2205	protein histidine kinase activity
GJJ12_RS22000	COG0745	RESPONSE REGULATOR receiver
GJJ12_RS22005	COG3045	CreA protein
GJJ12_RS22010	COG2207	Transcriptional regulator
GJJ12_RS22010	COG3708	Transcriptional regulator
GJJ12_RS22030	COG0741	lytic transglycosylase activity
GJJ12_RS22035	COG0488	(ABC) transporter
GJJ12_RS22045	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GJJ12_RS22050	COG0560	Phosphoserine phosphatase
GJJ12_RS22055	COG3726	membrane protein affecting hemolysin expression
GJJ12_RS22085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GJJ12_RS22090	COG0084	hydrolase, TatD family'
GJJ12_RS22095	COG4667	esterase of the alpha-beta hydrolase superfamily
GJJ12_RS22105	COG2823	Periplasmic or secreted lipoprotein
GJJ12_RS22115	COG1011	Hydrolase
GJJ12_RS22120	COG0456	acetyltransferase
GJJ12_RS22125	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GJJ12_RS22150	COG3706	GGDEF domain
GJJ12_RS22155	COG4114	ferric iron reductase
GJJ12_RS22160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJJ12_RS22165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GJJ12_RS22170	COG2197	response regulator
GJJ12_RS22175	COG2197	response regulator
GJJ12_RS22190	COG2966	Psort location CytoplasmicMembrane, score
GJJ12_RS22205	COG1484	DNA-dependent DNA replication
GJJ12_RS22220	COG5464	transposase or invertase
GJJ12_RS22230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GJJ12_RS22235	COG3716	PTS system mannose fructose sorbose family IID component
GJJ12_RS22240	COG3715	PTS system
GJJ12_RS22255	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GJJ12_RS22255	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GJJ12_RS22260	COG1214	PFAM Peptidase M22, glycoprotease
GJJ12_RS22260	COG0456	acetyltransferase
GJJ12_RS22270	COG1737	Transcriptional regulator
GJJ12_RS22275	COG0800	Aldolase
GJJ12_RS22280	COG3734	2-keto-3-deoxy-galactonokinase
GJJ12_RS22295	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GJJ12_RS22320	COG1846	Transcriptional regulator
GJJ12_RS22330	COG0179	Fumarylacetoacetate (FAA) hydrolase
GJJ12_RS22340	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS22345	COG3384	dioxygenase
GJJ12_RS22355	COG3971	2-oxopent-4-enoate hydratase activity
GJJ12_RS22375	COG2368	4-hydroxyphenylacetate
GJJ12_RS22380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GJJ12_RS22395	COG1966	Carbon starvation protein
GJJ12_RS22400	COG2879	small protein
GJJ12_RS22405	COG0523	cobalamin synthesis protein
GJJ12_RS22415	COG1012	belongs to the aldehyde dehydrogenase family
GJJ12_RS22420	COG5464	transposase or invertase
GJJ12_RS22425	COG2207	Transcriptional regulator
GJJ12_RS22425	COG1917	Cupin 2, conserved barrel domain protein
GJJ12_RS22435	COG2733	membrane
GJJ12_RS22450	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GJJ12_RS22455	COG1924	4 iron, 4 sulfur cluster binding
GJJ12_RS22470	COG1566	PFAM secretion protein HlyD family protein
GJJ12_RS22480	COG5457	Domain of unknown function (DUF1127)
GJJ12_RS22485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GJJ12_RS22495	COG0583	DNA-binding transcription factor activity
GJJ12_RS22500	COG2249	NAD(P)H dehydrogenase (quinone) activity
GJJ12_RS22510	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS22515	COG1129	ABC transporter
GJJ12_RS22520	COG1879	ABC-type sugar transport system periplasmic component
GJJ12_RS22530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJJ12_RS22535	COG1129	ABC transporter
GJJ12_RS22535	COG0842	Transport permease protein
GJJ12_RS22540	COG0842	Transport permease protein
GJJ12_RS22570	COG2850	peptidyl-arginine hydroxylation
GJJ12_RS22585	COG5002	protein histidine kinase activity
GJJ12_RS22590	COG0745	RESPONSE REGULATOR receiver
GJJ12_RS22595	COG1538	Outer membrane efflux protein
GJJ12_RS22600	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJJ12_RS22605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJJ12_RS22610	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GJJ12_RS22620	COG3040	lipid binding
GJJ12_RS22625	COG0789	Transcriptional regulator
GJJ12_RS22635	COG0300	oxidoreductase activity
GJJ12_RS22650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GJJ12_RS22670	COG3272	Protein of unknown function (DUF1722)
GJJ12_RS22675	COG4580	involved in the transport of maltose and maltodextrins
GJJ12_RS22680	COG2115	Belongs to the xylose isomerase family
GJJ12_RS22685	COG2211	Major facilitator Superfamily
GJJ12_RS22690	COG3507	Belongs to the glycosyl hydrolase 43 family
GJJ12_RS22700	COG0584	glycerophosphoryl diester phosphodiesterase
GJJ12_RS22710	COG1176	ABC-type spermidine putrescine transport system, permease component I
GJJ12_RS22775	COG1216	Glycosyl transferase, family 2
GJJ12_RS22860	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GJJ12_RS22920	COG0582	viral genome integration into host DNA
GJJ12_RS23010	COG0288	reversible hydration of carbon dioxide
GJJ12_RS23015	COG0659	secondary active sulfate transmembrane transporter activity
GJJ12_RS23020	COG1064	alcohol dehydrogenase
GJJ12_RS23025	COG1175	transmembrane transport
GJJ12_RS23030	COG0395	ABC-type sugar transport system, permease component
GJJ12_RS23035	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GJJ12_RS23040	COG3842	ATPase activity
GJJ12_RS23055	COG1082	Xylose isomerase domain protein TIM barrel
GJJ12_RS23065	COG3962	Belongs to the TPP enzyme family
GJJ12_RS23070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GJJ12_RS23075	COG0837	glucose binding
GJJ12_RS23075	COG1737	Transcriptional regulator
GJJ12_RS23085	COG3718	enzyme involved in inositol metabolism
GJJ12_RS23100	COG0433	COG0433 Predicted ATPase
GJJ12_RS23105	COG0795	lipopolysaccharide-transporting ATPase activity
GJJ12_RS23110	COG0795	lipopolysaccharide-transporting ATPase activity
GJJ12_RS23120	COG2927	DNA polymerase III (CHI subunit)
GJJ12_RS23125	COG0525	valine-tRNA ligase activity
GJJ12_RS23150	COG2731	YhcH YjgK YiaL family protein
GJJ12_RS23185	COG1263	PTS System
GJJ12_RS23185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJJ12_RS23190	COG0366	Alpha amylase catalytic
GJJ12_RS23195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJJ12_RS23200	COG1486	melibiose metabolic process
GJJ12_RS23225	COG0602	queuosine metabolic process
GJJ12_RS23230	COG2026	Addiction module toxin, RelE StbE family
GJJ12_RS23235	COG3077	Addiction module antitoxin, RelB DinJ family
GJJ12_RS23240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJJ12_RS23240	COG3711	transcriptional antiterminator
GJJ12_RS23245	COG2706	6-phosphogluconolactonase activity
GJJ12_RS23260	COG3964	amidohydrolase
GJJ12_RS23295	COG0312	modulator of DNA gyrase
GJJ12_RS23320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GJJ12_RS23330	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS23335	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS23340	COG1129	ABC transporter
GJJ12_RS23345	COG1879	ABC-type sugar transport system periplasmic component
GJJ12_RS23365	COG2105	PFAM AIG2 family protein
GJJ12_RS23370	COG2911	Protein conserved in bacteria
GJJ12_RS23375	COG0729	surface antigen
GJJ12_RS23385	COG1253	flavin adenine dinucleotide binding
GJJ12_RS23400	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GJJ12_RS23415	COG1733	regulation of RNA biosynthetic process
GJJ12_RS23420	COG0702	epimerase
GJJ12_RS23430	COG0697	spore germination
GJJ12_RS23440	COG1113	amino acid transport
GJJ12_RS23445	COG0545	Peptidyl-prolyl cis-trans isomerase
GJJ12_RS23450	COG3061	Opacity-associated protein A
GJJ12_RS23460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GJJ12_RS23465	COG2965	DNA replication, synthesis of RNA primer
GJJ12_RS23525	COG1073	alpha beta
GJJ12_RS23530	COG3650	response to hydrogen peroxide
GJJ12_RS23540	COG1960	acyl-CoA dehydrogenase activity
GJJ12_RS23545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJJ12_RS23550	COG0557	exoribonuclease II activity
GJJ12_RS23565	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GJJ12_RS23575	COG0330	HflC and HflK could
GJJ12_RS23580	COG0330	HflC and HflK could
GJJ12_RS23585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GJJ12_RS23605	COG0860	N-Acetylmuramoyl-L-alanine amidase
GJJ12_RS23610	COG0802	atpase or kinase
GJJ12_RS23615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GJJ12_RS23615	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GJJ12_RS23620	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GJJ12_RS23640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJJ12_RS23660	COG3264	Mechanosensitive ion channel
GJJ12_RS23660	COG1511	domain protein
GJJ12_RS23675	COG1053	succinate dehydrogenase
GJJ12_RS23680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GJJ12_RS23700	COG2076	Multidrug Resistance protein
GJJ12_RS23705	COG5510	response to toxic substance
GJJ12_RS23720	COG1509	lysine 2,3-aminomutase activity
GJJ12_RS23725	COG0745	RESPONSE REGULATOR receiver
GJJ12_RS23805	COG0531	amino acid
GJJ12_RS23810	COG3030	protein affecting phage T7 exclusion by the F plasmid
GJJ12_RS23815	COG1027	Aspartate ammonia-lyase
GJJ12_RS23820	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GJJ12_RS23835	COG1309	transcriptional regulator
GJJ12_RS23865	COG0457	Tetratricopeptide repeat
GJJ12_RS23870	COG1649	PFAM Uncharacterised BCR, COG1649
GJJ12_RS23870	COG0726	polysaccharide deacetylase
GJJ12_RS23875	COG1215	transferase activity, transferring glycosyl groups
GJJ12_RS23890	COG0861	Integral membrane protein TerC family
GJJ12_RS23930	COG1486	melibiose metabolic process
GJJ12_RS23935	COG2169	Transcriptional regulator
GJJ12_RS23945	COG2824	Alkylphosphonate utilization operon protein PhnA
GJJ12_RS23950	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GJJ12_RS23955	COG2188	Transcriptional regulator
GJJ12_RS23960	COG3624	Phosphonate C-P lyase system protein PhnG
GJJ12_RS23965	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GJJ12_RS23970	COG3626	phosphonate metabolism
GJJ12_RS23975	COG3627	carbon phosphorus lyase activity
GJJ12_RS23980	COG4107	phosphonate C-P lyase system protein PhnK
GJJ12_RS23985	COG4778	phosphonate C-P lyase system protein PhnL
GJJ12_RS23990	COG3454	Phosphonate metabolism
GJJ12_RS24000	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GJJ12_RS24010	COG4191	Histidine kinase
GJJ12_RS24010	COG0784	Response regulator, receiver
GJJ12_RS24015	COG1129	ABC transporter
GJJ12_RS24020	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS24055	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GJJ12_RS24060	COG1301	dicarboxylic acid transport
GJJ12_RS24070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GJJ12_RS24075	COG3162	membrane
GJJ12_RS24105	COG3539	Fimbrial protein
GJJ12_RS24110	COG1346	cytolysis
GJJ12_RS24115	COG1380	Effector of murein hydrolase LrgA
GJJ12_RS24120	COG0583	DNA-binding transcription factor activity
GJJ12_RS24125	COG0025	NhaP-type Na H and K H
GJJ12_RS24130	COG2252	PERMEase
GJJ12_RS24135	COG0625	glutathione transferase activity
GJJ12_RS24140	COG0789	Transcriptional regulator
GJJ12_RS24150	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GJJ12_RS24180	COG1234	tRNA 3'-trailer cleavage
GJJ12_RS24185	COG1609	Transcriptional regulator
GJJ12_RS24190	COG0483	inositol monophosphate 1-phosphatase activity
GJJ12_RS24200	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GJJ12_RS24220	COG4771	TonB-dependent receptor
GJJ12_RS24225	COG0741	lytic transglycosylase activity
GJJ12_RS24240	COG2315	Protein conserved in bacteria
GJJ12_RS24245	COG0432	Pfam Uncharacterised protein family UPF0047
GJJ12_RS24260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GJJ12_RS24265	COG0305	Participates in initiation and elongation during chromosome replication
GJJ12_RS24280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GJJ12_RS24290	COG0735	belongs to the Fur family
GJJ12_RS24295	COG3237	CsbD-like
GJJ12_RS24305	COG0534	Mate efflux family protein
GJJ12_RS24315	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GJJ12_RS24385	COG0251	oxidation-reduction process
GJJ12_RS24395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GJJ12_RS24405	COG0527	aspartate kinase activity
GJJ12_RS24460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GJJ12_RS24490	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GJJ12_RS24500	COG0456	acetyltransferase
GJJ12_RS24530	COG0151	Belongs to the GarS family
GJJ12_RS24540	COG4191	Histidine kinase
GJJ12_RS24545	COG3678	ATP-independent chaperone mediated protein folding
GJJ12_RS24580	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GJJ12_RS24595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GJJ12_RS24600	COG2104	thiamine diphosphate biosynthetic process
GJJ12_RS24615	COG3706	GGDEF domain
GJJ12_RS24625	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJJ12_RS24630	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GJJ12_RS24665	COG0250	Participates in transcription elongation, termination and antitermination
GJJ12_RS24740	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GJJ12_RS24750	COG1739	Uncharacterized protein family UPF0029
GJJ12_RS24790	COG0805	protein transport
GJJ12_RS24810	COG3165	ubiquinone biosynthetic process from chorismate
GJJ12_RS24840	COG0583	DNA-binding transcription factor activity
GJJ12_RS24845	COG0697	spore germination
GJJ12_RS24850	COG0561	phosphatase activity
GJJ12_RS24855	COG2267	carboxylic ester hydrolase activity
GJJ12_RS24860	COG1280	lysine exporter protein (LysE YggA)
GJJ12_RS24870	COG1280	lysine exporter protein (LysE YggA)
GJJ12_RS24900	COG0210	DNA helicase
GJJ12_RS24905	COG1011	Hydrolase
GJJ12_RS24935	COG3072	Adenylate cyclase
GJJ12_RS24950	COG2959	enzyme of heme biosynthesis
GJJ12_RS24955	COG3071	HemY protein
GJJ12_RS25000	COG2244	polysaccharide biosynthetic process
GJJ12_RS25005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GJJ12_RS25010	COG0456	acetyltransferase
GJJ12_RS25015	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GJJ12_RS25020	COG1088	dTDP-glucose 4,6-dehydratase activity
GJJ12_RS25025	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GJJ12_RS25030	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GJJ12_RS25040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GJJ12_RS25045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GJJ12_RS25050	COG3118	belongs to the thioredoxin family
GJJ12_RS25090	COG1811	Na channel or pump
GJJ12_RS25100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GJJ12_RS25105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GJJ12_RS25115	COG0583	DNA-binding transcription factor activity
GJJ12_RS25120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GJJ12_RS25135	COG3978	acetolactate synthase activity
GJJ12_RS25155	COG3085	chromosome segregation
GJJ12_RS25230	COG0583	DNA-binding transcription factor activity
GJJ12_RS25245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GJJ12_RS25260	COG3443	Belongs to the bacterial solute-binding protein 9 family
GJJ12_RS25265	COG2207	Transcriptional regulator
GJJ12_RS25275	COG0371	Dehydrogenase
GJJ12_RS25280	COG0697	spore germination
GJJ12_RS25290	COG0583	DNA-binding transcription factor activity
GJJ12_RS25300	COG0737	Belongs to the 5'-nucleotidase family
GJJ12_RS25310	COG0460	homoserine dehydrogenase
GJJ12_RS25310	COG0527	aspartate kinase activity
GJJ12_RS25315	COG0626	cystathionine gamma-synthase activity
GJJ12_RS25330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GJJ12_RS25335	COG1609	Transcriptional regulator
GJJ12_RS25340	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GJJ12_RS25355	COG1575	Belongs to the MenA family. Type 1 subfamily
GJJ12_RS25375	COG3678	ATP-independent chaperone mediated protein folding
GJJ12_RS25380	COG0745	RESPONSE REGULATOR receiver
GJJ12_RS25385	COG2205	protein histidine kinase activity
GJJ12_RS25390	COG2258	MOSC domain
GJJ12_RS25395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GJJ12_RS25435	COG1129	ABC transporter
GJJ12_RS25440	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS25445	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS25450	COG1454	alcohol dehydrogenase
GJJ12_RS25460	COG2211	Major facilitator Superfamily
GJJ12_RS25520	COG0205	6-phosphofructokinase activity
GJJ12_RS25540	COG0437	4 iron, 4 sulfur cluster binding
GJJ12_RS25545	COG2864	formate dehydrogenase
GJJ12_RS25560	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GJJ12_RS25570	COG0456	acetyltransferase
GJJ12_RS25585	COG1011	Hydrolase
GJJ12_RS25600	COG3852	Histidine kinase
GJJ12_RS25615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GJJ12_RS25640	COG4372	Transposase
GJJ12_RS25645	COG3436	PFAM IS66 Orf2 family protein
GJJ12_RS25665	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GJJ12_RS25670	COG3084	Protein conserved in bacteria
GJJ12_RS25680	COG1763	Mo-molybdopterin cofactor biosynthetic process
GJJ12_RS25705	COG2186	Transcriptional regulator
GJJ12_RS25715	COG1609	Transcriptional regulator
GJJ12_RS25720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GJJ12_RS25730	COG1172	Belongs to the binding-protein-dependent transport system permease family
GJJ12_RS25735	COG1129	ABC transporter
GJJ12_RS25765	COG1522	sequence-specific DNA binding
GJJ12_RS25770	COG0716	FMN binding
GJJ12_RS25785	COG3312	ion transport
GJJ12_RS25835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GJJ12_RS25840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GJJ12_RS25845	COG0573	inorganic phosphate transmembrane transporter activity
GJJ12_RS25850	COG0581	inorganic phosphate transmembrane transporter activity
GJJ12_RS25855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GJJ12_RS25860	COG0704	Plays a role in the regulation of phosphate uptake
GJJ12_RS25870	COG2382	esterase
GJJ12_RS25875	COG0363	glucosamine-6-phosphate deaminase activity
GJJ12_RS25880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GJJ12_RS25885	COG2252	PERMEase
GJJ12_RS25890	COG0431	NADPH-dependent FMN reductase
GJJ12_RS25895	COG2091	lysine biosynthetic process via aminoadipic acid
GJJ12_RS25925	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GJJ12_RS25980	COG3039	Transposase
GJJ12_RS26005	COG3039	Transposase
GJJ12_RS26080	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GJJ12_RS26300	COG5499	transcription regulator containing HTH domain
GJJ12_RS26355	COG2026	Addiction module toxin, RelE StbE family
GJJ12_RS26360	COG3077	Addiction module antitoxin, RelB DinJ family
GJJ12_RS26410	COG2814	Major facilitator Superfamily
GJJ12_RS26425	COG3111	PFAM Bacterial OB fold (BOF) protein
GJJ12_RS26430	COG2801	Transposase and inactivated derivatives
GJJ12_RS26450	COG0464	growth
GJJ12_RS26575	COG3344	reverse transcriptase
GJJ12_RS26665	COG1028	Short-chain dehydrogenase reductase Sdr
GJJ12_RS26670	COG1073	alpha beta
GJJ12_RS26745	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GJJ12_RS26765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJJ12_RS26770	COG0765	amino acid transport
GJJ12_RS26775	COG0765	amino acid transport
GJJ12_RS26780	COG1126	abc transporter atp-binding protein
GJJ12_RS26865	COG4372	Transposase
GJJ12_RS26870	COG3436	PFAM IS66 Orf2 family protein
GJJ12_RS26890	COG3344	reverse transcriptase
GJJ12_RS26930	COG0431	NADPH-dependent FMN reductase
GJJ12_RS26935	COG1393	Belongs to the ArsC family
GJJ12_RS26940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GJJ12_RS26950	COG0659	secondary active sulfate transmembrane transporter activity
GJJ12_RS26955	COG0589	response to stress
GJJ12_RS26965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GJJ12_RS27080	COG2076	Multidrug Resistance protein