locus-tag	class	description
HJX18_RS00015	COG2814	Major facilitator Superfamily
HJX18_RS00025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJX18_RS00050	COG0837	glucose binding
HJX18_RS00050	COG1737	Transcriptional regulator
HJX18_RS00055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJX18_RS00065	COG3962	Belongs to the TPP enzyme family
HJX18_RS00075	COG1082	Xylose isomerase domain protein TIM barrel
HJX18_RS00090	COG3842	ATPase activity
HJX18_RS00095	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HJX18_RS00100	COG0395	ABC-type sugar transport system, permease component
HJX18_RS00105	COG1175	transmembrane transport
HJX18_RS00110	COG1064	alcohol dehydrogenase
HJX18_RS00115	COG0659	secondary active sulfate transmembrane transporter activity
HJX18_RS00120	COG0288	reversible hydration of carbon dioxide
HJX18_RS00240	COG3706	GGDEF domain
HJX18_RS00275	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJX18_RS00305	COG0739	heme binding
HJX18_RS00315	COG2132	Multicopper oxidase
HJX18_RS00320	COG3667	copper resistance
HJX18_RS00325	COG2372	response to copper ion
HJX18_RS00330	COG1276	copper resistance
HJX18_RS00335	COG0745	RESPONSE REGULATOR receiver
HJX18_RS00340	COG2205	protein histidine kinase activity
HJX18_RS00345	COG0789	Transcriptional regulator
HJX18_RS00360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HJX18_RS00415	COG5499	transcription regulator containing HTH domain
HJX18_RS00420	COG4680	protein conserved in bacteria
HJX18_RS00510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HJX18_RS00550	COG0523	cobalamin synthesis protein
HJX18_RS00575	COG0523	cobalamin synthesis protein
HJX18_RS00580	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HJX18_RS00585	COG0735	belongs to the Fur family
HJX18_RS00655	COG0656	L-ascorbic acid biosynthetic process
HJX18_RS00660	COG2916	Histone family protein nucleoid-structuring protein H-NS
HJX18_RS00680	COG5654	RES domain protein
HJX18_RS00685	COG5642	Protein of unknown function (DUF2384)
HJX18_RS00700	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HJX18_RS00705	COG4772	TonB-dependent receptor
HJX18_RS00715	COG1595	DNA-templated transcription, initiation
HJX18_RS00730	COG3969	phosphoadenosine phosphosulfate
HJX18_RS00735	COG1475	DNA binding
HJX18_RS00755	COG2382	esterase
HJX18_RS00790	COG0500	methyltransferase
HJX18_RS00825	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HJX18_RS00835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJX18_RS00855	COG0523	cobalamin synthesis protein
HJX18_RS01025	COG1522	sequence-specific DNA binding
HJX18_RS01040	COG3321	synthase
HJX18_RS01040	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS01040	COG0604	alcohol dehydrogenase
HJX18_RS01115	COG1216	Glycosyl transferase, family 2
HJX18_RS01170	COG1176	ABC-type spermidine putrescine transport system, permease component I
HJX18_RS01180	COG0584	glycerophosphoryl diester phosphodiesterase
HJX18_RS01190	COG3507	Belongs to the glycosyl hydrolase 43 family
HJX18_RS01195	COG2211	Major facilitator Superfamily
HJX18_RS01200	COG2115	Belongs to the xylose isomerase family
HJX18_RS01210	COG4580	involved in the transport of maltose and maltodextrins
HJX18_RS01215	COG3272	Protein of unknown function (DUF1722)
HJX18_RS01235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HJX18_RS01250	COG0300	oxidoreductase activity
HJX18_RS01255	COG3631	Ketosteroid isomerase-related protein
HJX18_RS01260	COG0789	Transcriptional regulator
HJX18_RS01265	COG3040	lipid binding
HJX18_RS01275	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJX18_RS01280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJX18_RS01285	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJX18_RS01290	COG1538	Outer membrane efflux protein
HJX18_RS01295	COG0745	RESPONSE REGULATOR receiver
HJX18_RS01300	COG5002	protein histidine kinase activity
HJX18_RS01315	COG2850	peptidyl-arginine hydroxylation
HJX18_RS01345	COG0842	Transport permease protein
HJX18_RS01350	COG1129	ABC transporter
HJX18_RS01350	COG0842	Transport permease protein
HJX18_RS01355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJX18_RS01365	COG1879	ABC-type sugar transport system periplasmic component
HJX18_RS01370	COG1129	ABC transporter
HJX18_RS01375	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS01385	COG2249	NAD(P)H dehydrogenase (quinone) activity
HJX18_RS01390	COG0583	DNA-binding transcription factor activity
HJX18_RS01400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HJX18_RS01405	COG5457	Domain of unknown function (DUF1127)
HJX18_RS01415	COG1566	PFAM secretion protein HlyD family protein
HJX18_RS01430	COG1924	4 iron, 4 sulfur cluster binding
HJX18_RS01435	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HJX18_RS01450	COG2733	membrane
HJX18_RS01460	COG2207	Transcriptional regulator
HJX18_RS01460	COG1917	Cupin 2, conserved barrel domain protein
HJX18_RS01465	COG5464	transposase or invertase
HJX18_RS01470	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS01480	COG0523	cobalamin synthesis protein
HJX18_RS01485	COG2879	small protein
HJX18_RS01490	COG1966	Carbon starvation protein
HJX18_RS01495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HJX18_RS01500	COG2368	4-hydroxyphenylacetate
HJX18_RS01520	COG3971	2-oxopent-4-enoate hydratase activity
HJX18_RS01530	COG3384	dioxygenase
HJX18_RS01535	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS01545	COG0179	Fumarylacetoacetate (FAA) hydrolase
HJX18_RS01555	COG1846	Transcriptional regulator
HJX18_RS01585	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HJX18_RS01600	COG3734	2-keto-3-deoxy-galactonokinase
HJX18_RS01605	COG0800	Aldolase
HJX18_RS01610	COG1737	Transcriptional regulator
HJX18_RS01620	COG1214	PFAM Peptidase M22, glycoprotease
HJX18_RS01620	COG0456	acetyltransferase
HJX18_RS01625	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HJX18_RS01625	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HJX18_RS01640	COG3715	PTS system
HJX18_RS01645	COG3716	PTS system mannose fructose sorbose family IID component
HJX18_RS01650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HJX18_RS01660	COG5464	transposase or invertase
HJX18_RS01675	COG1484	DNA-dependent DNA replication
HJX18_RS01690	COG2966	Psort location CytoplasmicMembrane, score
HJX18_RS01705	COG2197	response regulator
HJX18_RS01710	COG2197	response regulator
HJX18_RS01715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HJX18_RS01720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJX18_RS01720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJX18_RS01725	COG4114	ferric iron reductase
HJX18_RS01730	COG3706	GGDEF domain
HJX18_RS01765	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HJX18_RS01770	COG0456	acetyltransferase
HJX18_RS01775	COG1011	Hydrolase
HJX18_RS01785	COG2823	Periplasmic or secreted lipoprotein
HJX18_RS01795	COG4667	esterase of the alpha-beta hydrolase superfamily
HJX18_RS01800	COG0084	hydrolase, TatD family'
HJX18_RS01805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HJX18_RS01835	COG3726	membrane protein affecting hemolysin expression
HJX18_RS01840	COG0560	Phosphoserine phosphatase
HJX18_RS01845	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HJX18_RS01855	COG0488	(ABC) transporter
HJX18_RS01860	COG0741	lytic transglycosylase activity
HJX18_RS01880	COG2207	Transcriptional regulator
HJX18_RS01880	COG3708	Transcriptional regulator
HJX18_RS01885	COG3045	CreA protein
HJX18_RS01890	COG0745	RESPONSE REGULATOR receiver
HJX18_RS01895	COG2205	protein histidine kinase activity
HJX18_RS01900	COG4452	Inner membrane protein CreD
HJX18_RS01905	COG0745	RESPONSE REGULATOR receiver
HJX18_RS01915	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HJX18_RS01930	COG0527	aspartate kinase activity
HJX18_RS01930	COG0460	homoserine dehydrogenase
HJX18_RS01940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HJX18_RS01955	COG1115	amino acid carrier protein
HJX18_RS01960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HJX18_RS01965	COG0521	Mo-molybdopterin cofactor biosynthetic process
HJX18_RS01970	COG0477	Major facilitator Superfamily
HJX18_RS01975	COG1584	GPR1 FUN34 yaaH family protein
HJX18_RS01980	COG4735	regulation of single-species biofilm formation
HJX18_RS02005	COG0583	DNA-binding transcription factor activity
HJX18_RS02025	COG0196	riboflavin kinase activity
HJX18_RS02040	COG1047	Peptidyl-prolyl cis-trans
HJX18_RS02065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HJX18_RS02080	COG0505	Belongs to the CarA family
HJX18_RS02125	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HJX18_RS02135	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HJX18_RS02140	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HJX18_RS02155	COG3493	citrate carrier protein
HJX18_RS02165	COG0564	pseudouridine synthase activity
HJX18_RS02175	COG0417	DNA replication proofreading
HJX18_RS02180	COG0235	Class ii aldolase
HJX18_RS02205	COG0586	Pfam SNARE associated Golgi protein
HJX18_RS02215	COG1178	ABC-type Fe3 transport system permease component
HJX18_RS02240	COG2814	Major facilitator Superfamily
HJX18_RS02245	COG2271	Major facilitator Superfamily
HJX18_RS02250	COG0583	DNA-binding transcription factor activity
HJX18_RS02260	COG0738	Major facilitator superfamily
HJX18_RS02310	COG0028	Belongs to the TPP enzyme family
HJX18_RS02320	COG1609	Transcriptional regulator
HJX18_RS02340	COG0768	penicillin binding
HJX18_RS02345	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HJX18_RS02350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HJX18_RS02365	COG0772	Belongs to the SEDS family
HJX18_RS02390	COG0849	cell division
HJX18_RS02395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HJX18_RS02415	COG0494	nUDIX hydrolase
HJX18_RS02440	COG1459	type II secretion system
HJX18_RS02445	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HJX18_RS02450	COG4969	Belongs to the N-Me-Phe pilin family
HJX18_RS02460	COG3023	N-Acetylmuramoyl-L-alanine amidase
HJX18_RS02465	COG3725	Membrane protein required for beta-lactamase induction
HJX18_RS02470	COG3940	Belongs to the glycosyl hydrolase 43 family
HJX18_RS02475	COG2211	Major facilitator Superfamily
HJX18_RS02480	COG1113	amino acid transport
HJX18_RS02485	COG2186	Transcriptional regulator
HJX18_RS02490	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HJX18_RS02495	COG0508	dehydrogenase complex catalyzes the overall conversion of
HJX18_RS02500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HJX18_RS02515	COG3064	Membrane
HJX18_RS02565	COG2132	Multicopper oxidase
HJX18_RS02570	COG4993	Dehydrogenase
HJX18_RS02585	COG0288	reversible hydration of carbon dioxide
HJX18_RS02590	COG1131	(ABC) transporter
HJX18_RS02595	COG0842	Transport permease protein
HJX18_RS02600	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJX18_RS02605	COG0726	polysaccharide deacetylase
HJX18_RS02625	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HJX18_RS02630	COG0617	tRNA 3'-terminal CCA addition
HJX18_RS02650	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HJX18_RS02655	COG1643	Atp-dependent helicase
HJX18_RS02750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HJX18_RS02755	COG4774	siderophore transport
HJX18_RS02760	COG1120	ATPase activity
HJX18_RS02765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HJX18_RS02770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJX18_RS02790	COG2860	membrane
HJX18_RS02810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HJX18_RS02815	COG3835	regulator
HJX18_RS02830	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HJX18_RS02835	COG0024	Methionine aminopeptidase
HJX18_RS02860	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HJX18_RS02870	COG0575	Belongs to the CDS family
HJX18_RS02875	COG0750	zinc metalloprotease
HJX18_RS02885	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HJX18_RS02930	COG0346	lactoylglutathione lyase activity
HJX18_RS02940	COG4568	rho-dependent transcription termination
HJX18_RS02955	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HJX18_RS02960	COG3015	lipoprotein NlpE involved in copper resistance
HJX18_RS02965	COG0791	NLP P60 protein
HJX18_RS02975	COG1720	tRNA m6t6A37 methyltransferase activity
HJX18_RS02985	COG1464	Belongs to the NlpA lipoprotein family
HJX18_RS02990	COG2011	ABC-type metal ion transport system permease component
HJX18_RS03000	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HJX18_RS03035	COG0656	L-ascorbic acid biosynthetic process
HJX18_RS03040	COG0583	DNA-binding transcription factor activity
HJX18_RS03045	COG2814	Major facilitator Superfamily
HJX18_RS03055	COG2226	methyltransferase
HJX18_RS03060	COG1388	LysM domain
HJX18_RS03060	COG0741	lytic transglycosylase activity
HJX18_RS03070	COG2226	methyltransferase
HJX18_RS03080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HJX18_RS03090	COG0583	DNA-binding transcription factor activity
HJX18_RS03100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HJX18_RS03105	COG1960	acyl-CoA dehydrogenase activity
HJX18_RS03115	COG0121	glutamine amidotransferase
HJX18_RS03120	COG3034	peptidoglycan biosynthetic process
HJX18_RS03135	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HJX18_RS03140	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HJX18_RS03155	COG2991	Protein conserved in bacteria
HJX18_RS03170	COG0454	-acetyltransferase
HJX18_RS03175	COG2195	Cleaves the N-terminal amino acid of tripeptides
HJX18_RS03195	COG1802	Transcriptional regulator
HJX18_RS03200	COG1113	amino acid transport
HJX18_RS03205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HJX18_RS03210	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS03215	COG0579	oxidoreductase
HJX18_RS03230	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HJX18_RS03235	COG0625	glutathione transferase activity
HJX18_RS03240	COG3775	system Galactitol-specific IIC component
HJX18_RS03245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HJX18_RS03250	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS03255	COG1070	Carbohydrate kinase
HJX18_RS03275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HJX18_RS03280	COG0508	dehydrogenase complex catalyzes the overall conversion of
HJX18_RS03285	COG0022	dehydrogenase e1 component
HJX18_RS03290	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HJX18_RS03295	COG2909	trisaccharide binding
HJX18_RS03300	COG0511	ligase activity, forming carbon-carbon bonds
HJX18_RS03305	COG0439	Biotin carboxylase
HJX18_RS03310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HJX18_RS03315	COG0697	spore germination
HJX18_RS03330	COG1984	allophanate hydrolase subunit 2
HJX18_RS03335	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HJX18_RS03340	COG0436	Aminotransferase
HJX18_RS03355	COG4221	oxidoreductase activity
HJX18_RS03365	COG0765	amino acid transport
HJX18_RS03395	COG0791	NLP P60 protein
HJX18_RS03410	COG3639	organic phosphonate transmembrane transporter activity
HJX18_RS03420	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HJX18_RS03445	COG3188	usher protein
HJX18_RS03460	COG0765	amino acid transport
HJX18_RS03465	COG4597	amino acid ABC transporter
HJX18_RS03470	COG1126	abc transporter atp-binding protein
HJX18_RS03475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJX18_RS03515	COG4302	ethanolamine ammonia-lyase activity
HJX18_RS03520	COG4303	Ethanolamine ammonia lyase large subunit
HJX18_RS03535	COG0833	amino acid
HJX18_RS03540	COG2040	homocysteine
HJX18_RS03545	COG4521	taurine ABC transporter
HJX18_RS03550	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HJX18_RS03555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HJX18_RS03560	COG2175	clavaminate synthase activity
HJX18_RS03570	COG0113	porphobilinogen synthase activity
HJX18_RS03575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HJX18_RS03580	COG1335	isochorismatase
HJX18_RS03585	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HJX18_RS03625	COG1785	Belongs to the alkaline phosphatase family
HJX18_RS03635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HJX18_RS03645	COG3416	Protein conserved in bacteria
HJX18_RS03650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HJX18_RS03660	COG4126	flavin adenine dinucleotide binding
HJX18_RS03675	COG1940	carbohydrate kinase activity
HJX18_RS03680	COG0419	ATPase involved in DNA repair
HJX18_RS03685	COG0420	3'-5' exonuclease activity
HJX18_RS03710	COG0366	Alpha amylase catalytic
HJX18_RS03715	COG0583	DNA-binding transcription factor activity
HJX18_RS03720	COG1335	isochorismatase
HJX18_RS03730	COG1228	amidohydrolase
HJX18_RS03740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJX18_RS03755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJX18_RS03760	COG0450	alkyl hydroperoxide reductase
HJX18_RS03785	COG1862	Preprotein translocase
HJX18_RS03790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HJX18_RS03795	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HJX18_RS03815	COG4238	major outer membrane lipoprotein
HJX18_RS03825	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HJX18_RS03825	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HJX18_RS03845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HJX18_RS03850	COG0667	Aldo Keto reductase
HJX18_RS03860	COG0142	geranyltranstransferase activity
HJX18_RS03885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HJX18_RS03895	COG2814	Major facilitator Superfamily
HJX18_RS03900	COG0673	inositol 2-dehydrogenase activity
HJX18_RS03915	COG1053	succinate dehydrogenase
HJX18_RS03925	COG1053	succinate dehydrogenase
HJX18_RS03930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HJX18_RS03935	COG1414	Transcriptional regulator
HJX18_RS03950	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HJX18_RS03955	COG1845	cytochrome c oxidase, subunit III
HJX18_RS03960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HJX18_RS03965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HJX18_RS03970	COG2223	nitrite transmembrane transporter activity
HJX18_RS03975	COG3056	Lipoprotein
HJX18_RS03980	COG0271	Belongs to the BolA IbaG family
HJX18_RS04005	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HJX18_RS04010	COG0776	regulation of translation
HJX18_RS04015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HJX18_RS04020	COG1555	photosystem II stabilization
HJX18_RS04025	COG0824	Thioesterase
HJX18_RS04035	COG4533	DNA binding
HJX18_RS04050	COG1522	sequence-specific DNA binding
HJX18_RS04055	COG1132	(ABC) transporter
HJX18_RS04060	COG1132	(ABC) transporter
HJX18_RS04065	COG0347	Belongs to the P(II) protein family
HJX18_RS04070	COG0004	ammonium transporteR
HJX18_RS04075	COG1946	Acyl-CoA thioesterase
HJX18_RS04080	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HJX18_RS04085	COG3695	enzyme binding
HJX18_RS04115	COG2364	Membrane
HJX18_RS04130	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HJX18_RS04145	COG2182	Extracellular solute-binding protein
HJX18_RS04150	COG1175	transmembrane transport
HJX18_RS04155	COG3833	ABC-type maltose transport systems, permease component
HJX18_RS04160	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HJX18_RS04165	COG1874	Beta-galactosidase
HJX18_RS04215	COG0110	maltose O-acetyltransferase activity
HJX18_RS04230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJX18_RS04235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJX18_RS04240	COG1309	transcriptional regulator
HJX18_RS04245	COG1196	nuclear chromosome segregation
HJX18_RS04245	COG3264	Mechanosensitive ion channel
HJX18_RS04250	COG5464	transposase or invertase
HJX18_RS04260	COG3923	Primosomal replication protein n
HJX18_RS04265	COG2832	Protein of unknown function (DUF454)
HJX18_RS04305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJX18_RS04310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HJX18_RS04310	COG4651	solute:proton antiporter activity
HJX18_RS04325	COG2223	nitrite transmembrane transporter activity
HJX18_RS04335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HJX18_RS04340	COG3735	TraB family
HJX18_RS04355	COG1585	Membrane protein implicated in regulation of membrane protease activity
HJX18_RS04360	COG0330	HflC and HflK could
HJX18_RS04365	COG4619	ABC transporter
HJX18_RS04370	COG0390	transport system, permease component
HJX18_RS04375	COG3118	belongs to the thioredoxin family
HJX18_RS04380	COG0300	oxidoreductase activity
HJX18_RS04385	COG2755	lipolytic protein G-D-S-L family
HJX18_RS04390	COG4181	ATPase activity
HJX18_RS04395	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HJX18_RS04430	COG3960	tartronate-semialdehyde synthase activity
HJX18_RS04435	COG3622	Belongs to the hyi family
HJX18_RS04440	COG2084	Dehydrogenase
HJX18_RS04450	COG1953	Uracil, thiamine, allantoin
HJX18_RS04465	COG1929	Belongs to the glycerate kinase type-1 family
HJX18_RS04470	COG3257	ureidoglycine aminohydrolase activity
HJX18_RS04475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HJX18_RS04480	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HJX18_RS04485	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HJX18_RS04490	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HJX18_RS04500	COG0549	Belongs to the carbamate kinase family
HJX18_RS04505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HJX18_RS04510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HJX18_RS04525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HJX18_RS04535	COG2501	S4 domain
HJX18_RS04585	COG3539	Fimbrial protein
HJX18_RS04590	COG3121	Chaperone
HJX18_RS04595	COG3188	usher protein
HJX18_RS04610	COG1560	Kdo2-lipid A biosynthetic process
HJX18_RS04620	COG3710	Transcriptional regulator
HJX18_RS04625	COG0531	amino acid
HJX18_RS04630	COG1982	Orn Lys Arg decarboxylase major
HJX18_RS04635	COG3104	oligopeptide transport
HJX18_RS04665	COG0673	inositol 2-dehydrogenase activity
HJX18_RS04680	COG1129	ABC transporter
HJX18_RS04685	COG4211	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS04740	COG1566	PFAM secretion protein HlyD family protein
HJX18_RS04745	COG1120	ATPase activity
HJX18_RS04750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJX18_RS04785	COG1473	amidohydrolase
HJX18_RS04790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJX18_RS04795	COG0667	Aldo Keto reductase
HJX18_RS04835	COG4680	protein conserved in bacteria
HJX18_RS04850	COG0531	amino acid
HJX18_RS04860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HJX18_RS04865	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS04880	COG1113	amino acid transport
HJX18_RS04885	COG2211	Major facilitator Superfamily
HJX18_RS04910	COG0668	transmembrane transport
HJX18_RS04915	COG0477	Major facilitator Superfamily
HJX18_RS04930	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HJX18_RS04930	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HJX18_RS04935	COG2222	sugar isomerase
HJX18_RS04940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HJX18_RS04945	COG3716	PTS system mannose fructose sorbose family IID component
HJX18_RS04955	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJX18_RS04965	COG0778	Nitroreductase
HJX18_RS04970	COG2315	Protein conserved in bacteria
HJX18_RS05015	COG3698	Phosphodiester glycosidase
HJX18_RS05025	COG4166	transmembrane transport
HJX18_RS05035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HJX18_RS05040	COG4608	Belongs to the ABC transporter superfamily
HJX18_RS05055	COG0697	spore germination
HJX18_RS05070	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HJX18_RS05080	COG4215	(ABC) transporter
HJX18_RS05090	COG4221	oxidoreductase activity
HJX18_RS05105	COG4608	Belongs to the ABC transporter superfamily
HJX18_RS05110	COG0444	Belongs to the ABC transporter superfamily
HJX18_RS05115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HJX18_RS05120	COG0601	transmembrane transport
HJX18_RS05125	COG0747	negative chemotaxis
HJX18_RS05150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HJX18_RS05160	COG0668	transmembrane transport
HJX18_RS05165	COG0583	DNA-binding transcription factor activity
HJX18_RS05175	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS05185	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS05190	COG1129	ABC transporter
HJX18_RS05200	COG1879	ABC-type sugar transport system periplasmic component
HJX18_RS05205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HJX18_RS05210	COG2390	Transcriptional regulator
HJX18_RS05215	COG3959	Transketolase, thiamine diphosphate binding domain
HJX18_RS05220	COG3958	Transketolase
HJX18_RS05225	COG2977	Belongs to the P-Pant transferase superfamily
HJX18_RS05230	COG4771	TonB-dependent receptor
HJX18_RS05235	COG2382	esterase
HJX18_RS05240	COG3251	PFAM MbtH domain protein
HJX18_RS05245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HJX18_RS05245	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HJX18_RS05250	COG1120	ATPase activity
HJX18_RS05255	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJX18_RS05260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJX18_RS05270	COG4592	Periplasmic binding protein
HJX18_RS05275	COG1169	isochorismate synthase
HJX18_RS05280	COG1021	2,3-dihydroxybenzoate-AMP ligase
HJX18_RS05285	COG1535	isochorismatase
HJX18_RS05285	COG3433	isochorismatase activity
HJX18_RS05290	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS05300	COG1966	Carbon starvation protein
HJX18_RS05305	COG2879	small protein
HJX18_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS05325	COG0371	Dehydrogenase
HJX18_RS05330	COG1129	ABC transporter
HJX18_RS05335	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS05370	COG2271	Major facilitator Superfamily
HJX18_RS05375	COG0483	inositol monophosphate 1-phosphatase activity
HJX18_RS05385	COG0402	S-adenosylhomocysteine deaminase activity
HJX18_RS05395	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HJX18_RS05410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HJX18_RS05420	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS05425	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS05430	COG1129	ABC transporter
HJX18_RS05455	COG0436	Aminotransferase
HJX18_RS05460	COG1475	DNA binding
HJX18_RS05465	COG3969	phosphoadenosine phosphosulfate
HJX18_RS05470	COG0583	DNA-binding transcription factor activity
HJX18_RS05475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HJX18_RS05495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HJX18_RS05500	COG3719	Belongs to the RNase T2 family
HJX18_RS05505	COG3069	C4-dicarboxylate transmembrane transporter activity
HJX18_RS05525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HJX18_RS05540	COG0583	DNA-binding transcription factor activity
HJX18_RS05555	COG1686	Belongs to the peptidase S11 family
HJX18_RS05560	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HJX18_RS05565	COG0772	Belongs to the SEDS family
HJX18_RS05570	COG0768	penicillin binding
HJX18_RS05580	COG0799	negative regulation of ribosome biogenesis
HJX18_RS05595	COG1466	dna polymerase III delta subunit
HJX18_RS05610	COG2888	peptidyl-tyrosine sulfation
HJX18_RS05625	COG1126	abc transporter atp-binding protein
HJX18_RS05630	COG0765	amino acid transport
HJX18_RS05635	COG0765	amino acid transport
HJX18_RS05660	COG1702	phosphate starvation-inducible protein PhoH
HJX18_RS05670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HJX18_RS05710	COG0367	asparagine synthase
HJX18_RS05715	COG0647	UMP catabolic process
HJX18_RS05720	COG1940	carbohydrate kinase activity
HJX18_RS05720	COG1846	Transcriptional regulator
HJX18_RS05725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HJX18_RS05765	COG0735	belongs to the Fur family
HJX18_RS05780	COG0596	Alpha beta hydrolase
HJX18_RS05790	COG0033	Phosphoglucomutase
HJX18_RS05800	COG0745	RESPONSE REGULATOR receiver
HJX18_RS05805	COG2205	protein histidine kinase activity
HJX18_RS05835	COG0415	Belongs to the DNA photolyase family
HJX18_RS05850	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HJX18_RS05855	COG1984	allophanate hydrolase subunit 2
HJX18_RS05890	COG2009	succinate dehydrogenase
HJX18_RS05895	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HJX18_RS05900	COG1053	succinate dehydrogenase
HJX18_RS05905	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HJX18_RS05910	COG0567	Dehydrogenase, E1 component
HJX18_RS05915	COG0508	dehydrogenase complex catalyzes the overall conversion of
HJX18_RS05925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HJX18_RS05935	COG1271	oxidase subunit
HJX18_RS05940	COG1294	oxidase, subunit
HJX18_RS05945	COG4890	Cyd operon protein YbgT
HJX18_RS05950	COG3790	cyd operon protein YbgE
HJX18_RS05955	COG0824	Thioesterase
HJX18_RS05960	COG0811	peptide transport
HJX18_RS05965	COG0848	biopolymer transport protein
HJX18_RS05970	COG3064	Membrane
HJX18_RS05980	COG2885	chlorophyll binding
HJX18_RS05985	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HJX18_RS06035	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HJX18_RS06040	COG3201	nicotinamide mononucleotide transporter
HJX18_RS06055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HJX18_RS06065	COG2017	converts alpha-aldose to the beta-anomer
HJX18_RS06075	COG1085	galactose-1-phosphate uridylyltransferase
HJX18_RS06090	COG1119	ATPase activity
HJX18_RS06100	COG2005	Transcriptional regulator
HJX18_RS06100	COG3585	molybdate ion transport
HJX18_RS06110	COG0725	ABC transporter, periplasmic molybdate-binding protein
HJX18_RS06115	COG4149	molybdate abc transporter
HJX18_RS06125	COG0561	phosphatase activity
HJX18_RS06150	COG2200	EAL domain
HJX18_RS06155	COG0789	Transcriptional regulator
HJX18_RS06190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJX18_RS06195	COG0589	response to stress
HJX18_RS06205	COG4677	pectinesterase activity
HJX18_RS06245	COG1881	PFAM PEBP family protein
HJX18_RS06250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HJX18_RS06265	COG2226	methyltransferase
HJX18_RS06290	COG0642	Histidine kinase
HJX18_RS06295	COG0745	RESPONSE REGULATOR receiver
HJX18_RS06315	COG0521	Mo-molybdopterin cofactor biosynthetic process
HJX18_RS06325	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HJX18_RS06330	COG0314	molybdopterin synthase activity
HJX18_RS06335	COG0670	Belongs to the BI1 family
HJX18_RS06340	COG0392	lysyltransferase activity
HJX18_RS06345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HJX18_RS06350	COG3568	Endonuclease Exonuclease Phosphatase
HJX18_RS06360	COG0842	Transport permease protein
HJX18_RS06365	COG0842	Transport permease protein
HJX18_RS06370	COG1131	(ABC) transporter
HJX18_RS06375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJX18_RS06380	COG1309	transcriptional regulator
HJX18_RS06385	COG0583	DNA-binding transcription factor activity
HJX18_RS06395	COG2271	Major facilitator Superfamily
HJX18_RS06400	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS06405	COG3959	Transketolase, thiamine diphosphate binding domain
HJX18_RS06410	COG3958	Transketolase
HJX18_RS06415	COG0513	Belongs to the DEAD box helicase family
HJX18_RS06420	COG1199	ATP-dependent helicase activity
HJX18_RS06425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HJX18_RS06435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HJX18_RS06445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HJX18_RS06455	COG0668	transmembrane transport
HJX18_RS06460	COG1126	abc transporter atp-binding protein
HJX18_RS06465	COG0765	amino acid transport
HJX18_RS06470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJX18_RS06490	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HJX18_RS06495	COG2194	sulfuric ester hydrolase activity
HJX18_RS06510	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HJX18_RS06515	COG2723	6-phospho-beta-galactosidase activity
HJX18_RS06520	COG2188	Transcriptional regulator
HJX18_RS06525	COG1376	ErfK ybiS ycfS ynhG family protein
HJX18_RS06530	COG2365	Tyrosine phosphatase family
HJX18_RS06535	COG0488	(ABC) transporter
HJX18_RS06545	COG2271	Major facilitator Superfamily
HJX18_RS06550	COG1609	Transcriptional regulator
HJX18_RS06560	COG0561	phosphatase activity
HJX18_RS06565	COG1882	Formate acetyltransferase
HJX18_RS06570	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HJX18_RS06575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HJX18_RS06595	COG0747	negative chemotaxis
HJX18_RS06615	COG2223	nitrite transmembrane transporter activity
HJX18_RS06625	COG2133	pyrroloquinoline quinone binding
HJX18_RS06630	COG0625	glutathione transferase activity
HJX18_RS06640	COG1686	Belongs to the peptidase S11 family
HJX18_RS06645	COG1349	DNA-binding transcription factor activity
HJX18_RS06650	COG0671	phosphoesterase, PA-phosphatase related
HJX18_RS06655	COG2814	Major facilitator Superfamily
HJX18_RS06660	COG0561	phosphatase activity
HJX18_RS06665	COG0738	Major facilitator superfamily
HJX18_RS06670	COG3226	Transcriptional regulator
HJX18_RS06700	COG0778	Nitroreductase
HJX18_RS06715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HJX18_RS06720	COG3842	ATPase activity
HJX18_RS06725	COG1176	ABC-type spermidine putrescine transport system, permease component I
HJX18_RS06730	COG1177	transmembrane transport
HJX18_RS06745	COG0745	RESPONSE REGULATOR receiver
HJX18_RS06750	COG5002	protein histidine kinase activity
HJX18_RS06755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJX18_RS06760	COG4160	amino acid transport
HJX18_RS06765	COG4215	(ABC) transporter
HJX18_RS06770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJX18_RS06775	COG1126	abc transporter atp-binding protein
HJX18_RS06785	COG5001	Diguanylate cyclase
HJX18_RS06785	COG4251	negative regulation of phosphorylation
HJX18_RS06785	COG3706	GGDEF domain
HJX18_RS06785	COG2203	Gaf domain
HJX18_RS06790	COG3023	N-Acetylmuramoyl-L-alanine amidase
HJX18_RS06795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HJX18_RS06800	COG0702	epimerase
HJX18_RS06805	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HJX18_RS06810	COG0028	Belongs to the TPP enzyme family
HJX18_RS06820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HJX18_RS06830	COG2431	L-lysine efflux transmembrane transporter activity
HJX18_RS06840	COG3593	DNA synthesis involved in DNA repair
HJX18_RS06845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJX18_RS06855	COG1278	Cold shock
HJX18_RS06865	COG0542	response to heat
HJX18_RS06880	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HJX18_RS06885	COG4988	ABC transporter
HJX18_RS06890	COG0492	ferredoxin-NADP+ reductase activity
HJX18_RS06905	COG1674	ftsk spoiiie
HJX18_RS06905	COG1178	ABC-type Fe3 transport system permease component
HJX18_RS06915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HJX18_RS06925	COG0243	molybdopterin cofactor binding
HJX18_RS06930	COG0437	4 iron, 4 sulfur cluster binding
HJX18_RS06935	COG3302	dmso reductase anchor subunit
HJX18_RS06945	COG0477	Major facilitator Superfamily
HJX18_RS06950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HJX18_RS06955	COG1882	Formate acetyltransferase
HJX18_RS06960	COG2116	formate transmembrane transporter activity
HJX18_RS06965	COG1944	ATP diphosphatase activity
HJX18_RS06970	COG2323	membrane
HJX18_RS06990	COG0539	negative regulation of cytoplasmic translation
HJX18_RS07000	COG2333	competence protein COMEC
HJX18_RS07000	COG0658	competence protein
HJX18_RS07015	COG3214	Protein conserved in bacteria
HJX18_RS07030	COG3173	Aminoglycoside phosphotransferase
HJX18_RS07035	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HJX18_RS07040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HJX18_RS07050	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HJX18_RS07060	COG2989	Protein conserved in bacteria
HJX18_RS07065	COG3108	Peptidase M15
HJX18_RS07070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HJX18_RS07075	COG1448	Aminotransferase
HJX18_RS07080	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HJX18_RS07100	COG0814	amino acid
HJX18_RS07110	COG1473	amidohydrolase
HJX18_RS07120	COG0308	aminopeptidase N
HJX18_RS07130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HJX18_RS07135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJX18_RS07140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HJX18_RS07145	COG0431	NADPH-dependent FMN reductase
HJX18_RS07160	COG0633	Ferredoxin
HJX18_RS07160	COG3217	Mosc domain protein beta barrel domain protein
HJX18_RS07170	COG0488	(ABC) transporter
HJX18_RS07175	COG2995	paraquat-inducible protein a
HJX18_RS07180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HJX18_RS07180	COG3008	intermembrane lipid transfer
HJX18_RS07185	COG3009	Protein conserved in bacteria
HJX18_RS07190	COG3130	regulation of translation
HJX18_RS07200	COG1067	ATP-dependent peptidase activity
HJX18_RS07220	COG3070	regulator of competence-specific genes
HJX18_RS07225	COG1289	transmembrane transporter activity
HJX18_RS07230	COG3304	Inner membrane component domain
HJX18_RS07235	COG0210	DNA helicase
HJX18_RS07245	COG1832	CoA-binding protein
HJX18_RS07260	COG1881	PFAM PEBP family protein
HJX18_RS07265	COG2207	Transcriptional regulator
HJX18_RS07310	COG0670	Belongs to the BI1 family
HJX18_RS07335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HJX18_RS07340	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS07345	COG4638	Rieske (2fe-2S)
HJX18_RS07350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HJX18_RS07355	COG0473	3-isopropylmalate dehydrogenase activity
HJX18_RS07360	COG0583	DNA-binding transcription factor activity
HJX18_RS07365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HJX18_RS07370	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS07375	COG1396	sequence-specific DNA binding
HJX18_RS07375	COG1917	Cupin 2, conserved barrel domain protein
HJX18_RS07380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HJX18_RS07385	COG0174	glutamine synthetase
HJX18_RS07390	COG0531	amino acid
HJX18_RS07405	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS07435	COG3729	General stress protein
HJX18_RS07445	COG2233	PERMEase
HJX18_RS07480	COG1309	transcriptional regulator
HJX18_RS07495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HJX18_RS07510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HJX18_RS07530	COG1702	phosphate starvation-inducible protein PhoH
HJX18_RS07535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HJX18_RS07545	COG1335	isochorismatase
HJX18_RS07555	COG0583	DNA-binding transcription factor activity
HJX18_RS07560	COG1309	transcriptional regulator
HJX18_RS07585	COG3381	protein complex oligomerization
HJX18_RS07620	COG5645	(Lipo)protein
HJX18_RS07635	COG1560	Kdo2-lipid A biosynthetic process
HJX18_RS07685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HJX18_RS07705	COG2814	Major facilitator Superfamily
HJX18_RS07710	COG0583	DNA-binding transcription factor activity
HJX18_RS07715	COG1530	ribonuclease E activity
HJX18_RS07735	COG1399	metal-binding, possibly nucleic acid-binding protein
HJX18_RS07755	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HJX18_RS07770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HJX18_RS07775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HJX18_RS07780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HJX18_RS07790	COG0470	DNA polymerase III
HJX18_RS07795	COG0084	hydrolase, TatD family'
HJX18_RS07805	COG0537	adenosine 5'-monophosphoramidase activity
HJX18_RS07810	COG5633	Lipoprotein
HJX18_RS07835	COG1252	NADH dehydrogenase
HJX18_RS07840	COG3134	Outer membrane lipoprotein
HJX18_RS07855	COG1309	transcriptional regulator
HJX18_RS07870	COG1388	LysM domain
HJX18_RS07870	COG1376	ErfK ybiS ycfS ynhG family protein
HJX18_RS07875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HJX18_RS07885	COG4591	ABC-type transport system involved in lipoprotein release permease component
HJX18_RS07895	COG4591	ABC-type transport system involved in lipoprotein release permease component
HJX18_RS07905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HJX18_RS07915	COG2390	Transcriptional regulator
HJX18_RS07920	COG0149	triose-phosphate isomerase activity
HJX18_RS07930	COG3395	kinase activity
HJX18_RS07945	COG0698	ribose 5-phosphate isomerase
HJX18_RS07950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HJX18_RS07955	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HJX18_RS07960	COG0318	PFAM AMP-dependent synthetase and ligase
HJX18_RS07975	COG1177	transmembrane transport
HJX18_RS07995	COG1943	Transposase
HJX18_RS08005	COG2850	peptidyl-arginine hydroxylation
HJX18_RS08010	COG2205	protein histidine kinase activity
HJX18_RS08030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HJX18_RS08050	COG1187	pseudouridine synthase activity
HJX18_RS08055	COG0538	isocitrate dehydrogenase activity
HJX18_RS08060	COG0582	viral genome integration into host DNA
HJX18_RS08075	COG3706	GGDEF domain
HJX18_RS08080	COG3300	MHYT domain
HJX18_RS08080	COG5001	Diguanylate cyclase
HJX18_RS08085	COG0538	isocitrate dehydrogenase activity
HJX18_RS08090	COG0640	Transcriptional regulator
HJX18_RS08115	COG3813	Protein conserved in bacteria
HJX18_RS08120	COG1063	alcohol dehydrogenase
HJX18_RS08125	COG3729	General stress protein
HJX18_RS08130	COG3685	Protein conserved in bacteria
HJX18_RS08135	COG3685	Protein conserved in bacteria
HJX18_RS08140	COG3546	catalase activity
HJX18_RS08145	COG1271	oxidase subunit
HJX18_RS08150	COG1294	oxidase, subunit
HJX18_RS08180	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HJX18_RS08185	COG0583	DNA-binding transcription factor activity
HJX18_RS08190	COG3706	GGDEF domain
HJX18_RS08195	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HJX18_RS08210	COG1560	Kdo2-lipid A biosynthetic process
HJX18_RS08220	COG3182	Iron-regulated membrane protein
HJX18_RS08240	COG2203	Gaf domain
HJX18_RS08240	COG2199	diguanylate cyclase activity
HJX18_RS08245	COG3042	response to heat
HJX18_RS08250	COG3189	MarR family transcriptional regulator
HJX18_RS08255	COG1683	Conserved Protein
HJX18_RS08260	COG0504	CTP synthase activity
HJX18_RS08265	COG2807	transmembrane transport
HJX18_RS08270	COG2207	Transcriptional regulator
HJX18_RS08280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HJX18_RS08285	COG0859	PFAM glycosyl transferase family 9
HJX18_RS08295	COG3344	reverse transcriptase
HJX18_RS08300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HJX18_RS08305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HJX18_RS08310	COG0583	DNA-binding transcription factor activity
HJX18_RS08315	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS08340	COG0386	Belongs to the glutathione peroxidase family
HJX18_RS08355	COG2766	serine protein kinase
HJX18_RS08360	COG3713	MltA-interacting MipA family protein
HJX18_RS08365	COG0656	L-ascorbic acid biosynthetic process
HJX18_RS08385	COG3139	Protein of unknown function (DUF1315)
HJX18_RS08400	COG1335	isochorismatase
HJX18_RS08405	COG0252	asparaginase activity
HJX18_RS08410	COG0616	signal peptide processing
HJX18_RS08415	COG0778	Nitroreductase
HJX18_RS08425	COG0709	Synthesizes selenophosphate from selenide and ATP
HJX18_RS08430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HJX18_RS08435	COG0604	alcohol dehydrogenase
HJX18_RS08435	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS08435	COG3321	synthase
HJX18_RS08440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HJX18_RS08445	COG0494	nUDIX hydrolase
HJX18_RS08450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HJX18_RS08455	COG2897	thiosulfate sulfurtransferase activity
HJX18_RS08460	COG4136	ATPase activity
HJX18_RS08465	COG4135	transport system, permease component
HJX18_RS08470	COG4134	Bacterial extracellular solute-binding protein
HJX18_RS08475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HJX18_RS08480	COG0398	Pfam SNARE associated Golgi protein
HJX18_RS08485	COG0398	Pfam SNARE associated Golgi protein
HJX18_RS08490	COG0708	Exodeoxyribonuclease III
HJX18_RS08500	COG3138	arginine N-succinyltransferase
HJX18_RS08510	COG3724	N-succinylarginine dihydrolase activity
HJX18_RS08520	COG3678	ATP-independent chaperone mediated protein folding
HJX18_RS08525	COG0322	excinuclease ABC activity
HJX18_RS08535	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HJX18_RS08540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJX18_RS08550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJX18_RS08555	COG1447	Phosphotransferase system cellobiose-specific component IIA
HJX18_RS08560	COG2169	Transcriptional regulator
HJX18_RS08560	COG1917	Cupin 2, conserved barrel domain protein
HJX18_RS08565	COG1486	melibiose metabolic process
HJX18_RS08575	COG0753	catalase activity
HJX18_RS08590	COG1988	membrane-bound metal-dependent
HJX18_RS08595	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS08600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HJX18_RS08630	COG0727	PFAM Uncharacterised protein family (UPF0153)
HJX18_RS08635	COG3047	cAMP biosynthetic process
HJX18_RS08645	COG4774	siderophore transport
HJX18_RS08680	COG0134	indole-3-glycerol-phosphate synthase activity
HJX18_RS08680	COG0135	phosphoribosylanthranilate isomerase activity
HJX18_RS08685	COG0512	Glutamine amidotransferase of anthranilate synthase
HJX18_RS08685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HJX18_RS08690	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HJX18_RS08700	COG0009	L-threonylcarbamoyladenylate synthase
HJX18_RS08710	COG0583	DNA-binding transcription factor activity
HJX18_RS08720	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HJX18_RS08725	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS08735	COG0616	signal peptide processing
HJX18_RS08760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HJX18_RS08770	COG0671	phosphoesterase, PA-phosphatase related
HJX18_RS08775	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HJX18_RS08780	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HJX18_RS08790	COG0023	Translation Initiation Factor
HJX18_RS08805	COG1349	DNA-binding transcription factor activity
HJX18_RS08820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HJX18_RS08820	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HJX18_RS08825	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HJX18_RS08835	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HJX18_RS08850	COG4171	peptide transport system, permease
HJX18_RS08865	COG0702	epimerase
HJX18_RS08880	COG1473	amidohydrolase
HJX18_RS08890	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HJX18_RS08895	COG1842	Phage shock protein A
HJX18_RS08905	COG1983	PspC domain protein
HJX18_RS08915	COG3106	COG3106 Predicted ATPase
HJX18_RS08925	COG0583	DNA-binding transcription factor activity
HJX18_RS08930	COG1486	melibiose metabolic process
HJX18_RS08940	COG3180	Ammonia monooxygenase
HJX18_RS08945	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HJX18_RS08950	COG4948	Mandelate Racemase Muconate Lactonizing
HJX18_RS08955	COG2866	Carboxypeptidase
HJX18_RS08965	COG4166	transmembrane transport
HJX18_RS08990	COG0656	L-ascorbic acid biosynthetic process
HJX18_RS09010	COG0583	DNA-binding transcription factor activity
HJX18_RS09015	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS09020	COG1078	dGTPase activity
HJX18_RS09025	COG0693	protein deglycase activity
HJX18_RS09055	COG2885	chlorophyll binding
HJX18_RS09140	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS09145	COG1309	transcriptional regulator
HJX18_RS09150	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS09170	COG0583	DNA-binding transcription factor activity
HJX18_RS09200	COG0604	alcohol dehydrogenase
HJX18_RS09205	COG0436	Aminotransferase
HJX18_RS09220	COG2011	ABC-type metal ion transport system permease component
HJX18_RS09225	COG1448	Aminotransferase
HJX18_RS09235	COG1522	sequence-specific DNA binding
HJX18_RS09240	COG1113	amino acid transport
HJX18_RS09255	COG0673	inositol 2-dehydrogenase activity
HJX18_RS09260	COG1349	DNA-binding transcription factor activity
HJX18_RS09270	COG0513	Belongs to the DEAD box helicase family
HJX18_RS09275	COG0513	Belongs to the DEAD box helicase family
HJX18_RS09285	COG0589	response to stress
HJX18_RS09295	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HJX18_RS09300	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HJX18_RS09300	COG0674	pyruvate-flavodoxin oxidoreductase activity
HJX18_RS09300	COG1013	pyruvate-flavodoxin oxidoreductase activity
HJX18_RS09300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HJX18_RS09305	COG3042	response to heat
HJX18_RS09310	COG3187	Heat shock protein
HJX18_RS09315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HJX18_RS09320	COG0586	Pfam SNARE associated Golgi protein
HJX18_RS09325	COG2911	Protein conserved in bacteria
HJX18_RS09335	COG3784	Protein of unknown function (DUF1318)
HJX18_RS09340	COG2207	Transcriptional regulator
HJX18_RS09345	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS09360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJX18_RS09370	COG1126	abc transporter atp-binding protein
HJX18_RS09375	COG0583	DNA-binding transcription factor activity
HJX18_RS09380	COG2072	flavoprotein involved in K transport
HJX18_RS09395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HJX18_RS09415	COG2030	dehydratase
HJX18_RS09415	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS09420	COG3396	Phenylacetate-CoA oxygenase
HJX18_RS09425	COG3460	Phenylacetate-CoA oxygenase
HJX18_RS09430	COG3396	Phenylacetate-CoA oxygenase
HJX18_RS09435	COG2151	metal-sulfur cluster biosynthetic enzyme
HJX18_RS09440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HJX18_RS09445	COG1024	Enoyl-CoA hydratase
HJX18_RS09450	COG1024	Enoyl-CoA hydratase
HJX18_RS09455	COG1250	3-hydroxyacyl-CoA dehydrogenase
HJX18_RS09460	COG2050	protein possibly involved in aromatic compounds catabolism
HJX18_RS09465	COG0183	Belongs to the thiolase family
HJX18_RS09470	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HJX18_RS09475	COG3327	negative regulation of DNA-templated transcription, initiation
HJX18_RS09480	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HJX18_RS09495	COG1643	Atp-dependent helicase
HJX18_RS09500	COG4122	O-methyltransferase activity
HJX18_RS09525	COG0583	DNA-binding transcription factor activity
HJX18_RS09530	COG0667	Aldo Keto reductase
HJX18_RS09535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HJX18_RS09550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HJX18_RS09555	COG3138	arginine N-succinyltransferase
HJX18_RS09560	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS09565	COG3724	N-succinylarginine dihydrolase activity
HJX18_RS09570	COG2988	succinylglutamate desuccinylase activity
HJX18_RS09575	COG1113	amino acid transport
HJX18_RS09580	COG0477	Major facilitator Superfamily
HJX18_RS09585	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HJX18_RS09595	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS09600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HJX18_RS09605	COG0401	homolog of Blt101
HJX18_RS09610	COG5562	phage envelope protein
HJX18_RS09615	COG0425	Belongs to the sulfur carrier protein TusA family
HJX18_RS09620	COG2391	methyltransferase activity
HJX18_RS09645	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HJX18_RS09650	COG1263	PTS System
HJX18_RS09650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJX18_RS09655	COG1609	Transcriptional regulator
HJX18_RS09660	COG5339	Protein conserved in bacteria
HJX18_RS09665	COG1482	cell wall glycoprotein biosynthetic process
HJX18_RS09670	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HJX18_RS09670	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HJX18_RS09675	COG0114	fumarate hydratase activity
HJX18_RS09685	COG2205	protein histidine kinase activity
HJX18_RS09695	COG0745	RESPONSE REGULATOR receiver
HJX18_RS09700	COG3136	membrane protein required for alginate biosynthesis
HJX18_RS09710	COG0531	amino acid
HJX18_RS09730	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HJX18_RS09735	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HJX18_RS09750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HJX18_RS09765	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HJX18_RS09770	COG1473	amidohydrolase
HJX18_RS09780	COG0583	DNA-binding transcription factor activity
HJX18_RS09785	COG2840	Smr protein MutS2
HJX18_RS09790	COG1414	Transcriptional regulator
HJX18_RS09800	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HJX18_RS09805	COG0183	Belongs to the thiolase family
HJX18_RS09815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HJX18_RS09820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HJX18_RS09830	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HJX18_RS09830	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HJX18_RS09850	COG4565	transcriptional regulatory protein
HJX18_RS09855	COG3290	protein histidine kinase activity
HJX18_RS09880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HJX18_RS09890	COG0679	Auxin Efflux Carrier
HJX18_RS09920	COG0628	permease
HJX18_RS09940	COG3591	Belongs to the peptidase S1B family
HJX18_RS09960	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HJX18_RS09965	COG2814	Major facilitator Superfamily
HJX18_RS09970	COG0583	DNA-binding transcription factor activity
HJX18_RS09975	COG1940	carbohydrate kinase activity
HJX18_RS09980	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HJX18_RS09995	COG3302	dmso reductase anchor subunit
HJX18_RS10000	COG0437	4 iron, 4 sulfur cluster binding
HJX18_RS10005	COG0243	molybdopterin cofactor binding
HJX18_RS10020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HJX18_RS10035	COG2271	Major facilitator Superfamily
HJX18_RS10040	COG0246	Mannitol dehydrogenase
HJX18_RS10045	COG0589	response to stress
HJX18_RS10050	COG1802	Transcriptional regulator
HJX18_RS10055	COG4221	oxidoreductase activity
HJX18_RS10070	COG2207	Transcriptional regulator
HJX18_RS10075	COG2135	peptidase activity
HJX18_RS10090	COG2197	response regulator
HJX18_RS10110	COG0071	Belongs to the small heat shock protein (HSP20) family
HJX18_RS10115	COG1546	Belongs to the CinA family
HJX18_RS10120	COG2200	EAL domain
HJX18_RS10135	COG3708	Transcriptional regulator
HJX18_RS10135	COG2207	Transcriptional regulator
HJX18_RS10140	COG2610	gluconate transmembrane transporter activity
HJX18_RS10145	COG3622	Belongs to the hyi family
HJX18_RS10150	COG0235	Class ii aldolase
HJX18_RS10155	COG3395	kinase activity
HJX18_RS10160	COG2084	Dehydrogenase
HJX18_RS10165	COG1349	DNA-binding transcription factor activity
HJX18_RS10180	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HJX18_RS10185	COG2223	nitrite transmembrane transporter activity
HJX18_RS10225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HJX18_RS10230	COG0683	leucine binding
HJX18_RS10260	COG2814	Major facilitator Superfamily
HJX18_RS10265	COG0697	spore germination
HJX18_RS10275	COG4977	sequence-specific DNA binding
HJX18_RS10305	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS10310	COG2731	YhcH YjgK YiaL family protein
HJX18_RS10325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HJX18_RS10335	COG3395	kinase activity
HJX18_RS10340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HJX18_RS10345	COG1349	DNA-binding transcription factor activity
HJX18_RS10350	COG0039	L-malate dehydrogenase activity
HJX18_RS10360	COG0583	DNA-binding transcription factor activity
HJX18_RS10365	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS10380	COG2199	diguanylate cyclase activity
HJX18_RS10450	COG0477	Major facilitator Superfamily
HJX18_RS10465	COG2070	2-Nitropropane dioxygenase
HJX18_RS10470	COG2011	ABC-type metal ion transport system permease component
HJX18_RS10490	COG4628	conserved protein (DUF2132)
HJX18_RS10505	COG2207	Transcriptional regulator
HJX18_RS10535	COG2233	PERMEase
HJX18_RS10540	COG3648	Uricase
HJX18_RS10540	COG3195	allantoin biosynthetic process
HJX18_RS10545	COG2351	hydroxyisourate hydrolase activity
HJX18_RS10550	COG1396	sequence-specific DNA binding
HJX18_RS10555	COG3550	peptidyl-serine autophosphorylation
HJX18_RS10570	COG3188	usher protein
HJX18_RS10605	COG3300	MHYT domain
HJX18_RS10605	COG5001	Diguanylate cyclase
HJX18_RS10610	COG2819	hydrolase of the alpha beta superfamily
HJX18_RS10630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJX18_RS10630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJX18_RS10635	COG2814	Major facilitator Superfamily
HJX18_RS10650	COG1263	PTS System
HJX18_RS10650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJX18_RS10655	COG2186	Transcriptional regulator
HJX18_RS10675	COG3835	regulator
HJX18_RS10680	COG1929	Belongs to the glycerate kinase type-1 family
HJX18_RS10720	COG0583	DNA-binding transcription factor activity
HJX18_RS10750	COG3118	belongs to the thioredoxin family
HJX18_RS10760	COG1271	oxidase subunit
HJX18_RS10765	COG1294	oxidase, subunit
HJX18_RS10775	COG0583	DNA-binding transcription factor activity
HJX18_RS10780	COG0814	amino acid
HJX18_RS10785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HJX18_RS10790	COG0626	cystathionine gamma-synthase activity
HJX18_RS10795	COG0583	DNA-binding transcription factor activity
HJX18_RS10800	COG0251	oxidation-reduction process
HJX18_RS10815	COG1473	amidohydrolase
HJX18_RS10825	COG0667	Aldo Keto reductase
HJX18_RS10830	COG3386	PFAM SMP-30 Gluconolaconase
HJX18_RS10835	COG0667	Aldo Keto reductase
HJX18_RS10840	COG0667	Aldo Keto reductase
HJX18_RS10855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HJX18_RS10855	COG0456	acetyltransferase
HJX18_RS10880	COG1652	LysM domain
HJX18_RS10910	COG1609	Transcriptional regulator
HJX18_RS10920	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS10935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HJX18_RS10945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HJX18_RS10950	COG0583	DNA-binding transcription factor activity
HJX18_RS10955	COG0583	DNA-binding transcription factor activity
HJX18_RS10975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJX18_RS10985	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HJX18_RS10990	COG3037	sugar-specific permease SgaT UlaA
HJX18_RS11000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJX18_RS11005	COG1609	Transcriptional regulator
HJX18_RS11015	COG2223	nitrite transmembrane transporter activity
HJX18_RS11045	COG0477	Major facilitator Superfamily
HJX18_RS11050	COG4529	Protein conserved in bacteria
HJX18_RS11055	COG1902	pentaerythritol trinitrate reductase activity
HJX18_RS11065	COG0583	DNA-binding transcription factor activity
HJX18_RS11070	COG2070	2-Nitropropane dioxygenase
HJX18_RS11080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HJX18_RS11135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HJX18_RS11160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HJX18_RS11185	COG2207	Transcriptional regulator
HJX18_RS11200	COG1335	isochorismatase
HJX18_RS11205	COG0406	alpha-ribazole phosphatase activity
HJX18_RS11245	COG1953	Uracil, thiamine, allantoin
HJX18_RS11250	COG0402	S-adenosylhomocysteine deaminase activity
HJX18_RS11255	COG3706	GGDEF domain
HJX18_RS11260	COG1609	Transcriptional regulator
HJX18_RS11270	COG0673	inositol 2-dehydrogenase activity
HJX18_RS11285	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HJX18_RS11290	COG1116	anion transmembrane transporter activity
HJX18_RS11295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HJX18_RS11300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HJX18_RS11305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HJX18_RS11310	COG0076	glutamate decarboxylase activity
HJX18_RS11325	COG2205	protein histidine kinase activity
HJX18_RS11330	COG0745	RESPONSE REGULATOR receiver
HJX18_RS11335	COG0596	Alpha beta hydrolase
HJX18_RS11375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HJX18_RS11375	COG0519	Catalyzes the synthesis of GMP from XMP
HJX18_RS11395	COG0583	DNA-binding transcription factor activity
HJX18_RS11405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HJX18_RS11410	COG1285	pathogenesis
HJX18_RS11415	COG2814	Major facilitator Superfamily
HJX18_RS11420	COG1447	Phosphotransferase system cellobiose-specific component IIA
HJX18_RS11425	COG0583	DNA-binding transcription factor activity
HJX18_RS11430	COG0243	molybdopterin cofactor binding
HJX18_RS11435	COG3781	membrane
HJX18_RS11460	COG1764	response to oxidative stress
HJX18_RS11470	COG3111	PFAM Bacterial OB fold (BOF) protein
HJX18_RS11480	COG2323	membrane
HJX18_RS11490	COG0366	Alpha amylase catalytic
HJX18_RS11500	COG3685	Protein conserved in bacteria
HJX18_RS11510	COG3729	General stress protein
HJX18_RS11515	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS11555	COG0488	(ABC) transporter
HJX18_RS11570	COG1064	alcohol dehydrogenase
HJX18_RS11575	COG0747	negative chemotaxis
HJX18_RS11595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJX18_RS11605	COG2814	Major facilitator Superfamily
HJX18_RS11615	COG2326	polyphosphate kinase activity
HJX18_RS11630	COG2864	formate dehydrogenase
HJX18_RS11635	COG0437	4 iron, 4 sulfur cluster binding
HJX18_RS11660	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HJX18_RS11670	COG3485	protocatechuate 3,4-dioxygenase
HJX18_RS11675	COG4829	muconolactone delta-isomerase
HJX18_RS11680	COG4948	Mandelate Racemase Muconate Lactonizing
HJX18_RS11685	COG1414	Transcriptional regulator
HJX18_RS11705	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HJX18_RS11710	COG1140	nitrate reductase beta subunit
HJX18_RS11715	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HJX18_RS11720	COG2181	nitrate reductase activity
HJX18_RS11725	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HJX18_RS11730	COG1178	ABC-type Fe3 transport system permease component
HJX18_RS11735	COG1840	ABC-type Fe3 transport system, periplasmic component
HJX18_RS11740	COG3842	ATPase activity
HJX18_RS11745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HJX18_RS11755	COG0625	glutathione transferase activity
HJX18_RS11765	COG1126	abc transporter atp-binding protein
HJX18_RS11770	COG0765	amino acid transport
HJX18_RS11785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJX18_RS11790	COG1473	amidohydrolase
HJX18_RS11795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJX18_RS11800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HJX18_RS11825	COG4772	TonB-dependent receptor
HJX18_RS11830	COG1228	amidohydrolase
HJX18_RS11835	COG3691	Protein conserved in bacteria
HJX18_RS11850	COG2130	NADP-dependent
HJX18_RS11860	COG1247	-acetyltransferase
HJX18_RS11865	COG3238	Protein conserved in bacteria
HJX18_RS11875	COG0747	negative chemotaxis
HJX18_RS11885	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS11920	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS11925	COG1177	transmembrane transport
HJX18_RS11930	COG1176	ABC-type spermidine putrescine transport system, permease component I
HJX18_RS11935	COG3842	ATPase activity
HJX18_RS11940	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HJX18_RS11945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HJX18_RS11950	COG1271	oxidase subunit
HJX18_RS11955	COG1294	oxidase, subunit
HJX18_RS11975	COG0826	peptidase U32
HJX18_RS11985	COG1396	sequence-specific DNA binding
HJX18_RS11990	COG3135	benzoate transporter
HJX18_RS11995	COG3708	Transcriptional regulator
HJX18_RS11995	COG2207	Transcriptional regulator
HJX18_RS12010	COG0500	methyltransferase
HJX18_RS12015	COG1275	C4-dicarboxylate transporter malic acid transport protein
HJX18_RS12020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HJX18_RS12025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HJX18_RS12040	COG2272	Belongs to the type-B carboxylesterase lipase family
HJX18_RS12045	COG5383	Protein conserved in bacteria
HJX18_RS12050	COG3485	protocatechuate 3,4-dioxygenase
HJX18_RS12055	COG3485	protocatechuate 3,4-dioxygenase
HJX18_RS12060	COG0583	DNA-binding transcription factor activity
HJX18_RS12080	COG3038	cytochrome b561
HJX18_RS12100	COG2814	Major facilitator Superfamily
HJX18_RS12110	COG0673	inositol 2-dehydrogenase activity
HJX18_RS12120	COG2723	6-phospho-beta-galactosidase activity
HJX18_RS12155	COG4659	FMN binding
HJX18_RS12165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HJX18_RS12175	COG0625	glutathione transferase activity
HJX18_RS12180	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HJX18_RS12195	COG3895	Periplasmic Protein
HJX18_RS12210	COG3706	GGDEF domain
HJX18_RS12225	COG1566	PFAM secretion protein HlyD family protein
HJX18_RS12230	COG1289	transmembrane transporter activity
HJX18_RS12235	COG2032	superoxide dismutase activity
HJX18_RS12240	COG4989	oxidoreductase activity
HJX18_RS12245	COG3313	Fe-S protein
HJX18_RS12250	COG1309	transcriptional regulator
HJX18_RS12255	COG1902	pentaerythritol trinitrate reductase activity
HJX18_RS12260	COG0346	lactoylglutathione lyase activity
HJX18_RS12270	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HJX18_RS12275	COG0791	NLP P60 protein
HJX18_RS12290	COG2814	Major facilitator Superfamily
HJX18_RS12305	COG0583	DNA-binding transcription factor activity
HJX18_RS12310	COG2814	Major facilitator Superfamily
HJX18_RS12315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HJX18_RS12320	COG0307	riboflavin synthase, alpha
HJX18_RS12365	COG0300	oxidoreductase activity
HJX18_RS12385	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HJX18_RS12425	COG1349	DNA-binding transcription factor activity
HJX18_RS12430	COG0346	lactoylglutathione lyase activity
HJX18_RS12455	COG0444	Belongs to the ABC transporter superfamily
HJX18_RS12460	COG4608	Belongs to the ABC transporter superfamily
HJX18_RS12490	COG0531	amino acid
HJX18_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS12505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HJX18_RS12540	COG0402	S-adenosylhomocysteine deaminase activity
HJX18_RS12565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HJX18_RS12570	COG0277	FAD linked oxidase domain protein
HJX18_RS12585	COG2814	Major facilitator Superfamily
HJX18_RS12615	COG0583	DNA-binding transcription factor activity
HJX18_RS12625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HJX18_RS12635	COG1250	3-hydroxyacyl-CoA dehydrogenase
HJX18_RS12640	COG2610	gluconate transmembrane transporter activity
HJX18_RS12645	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS12675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJX18_RS12690	COG0745	RESPONSE REGULATOR receiver
HJX18_RS12695	COG5002	protein histidine kinase activity
HJX18_RS12695	COG3850	Histidine kinase
HJX18_RS12720	COG4235	cytochrome complex assembly
HJX18_RS12720	COG3088	subunit of a heme lyase
HJX18_RS12725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HJX18_RS12730	COG1138	Cytochrome C-type biogenesis protein
HJX18_RS12745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HJX18_RS12750	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HJX18_RS12755	COG4133	protoheme IX ABC transporter activity
HJX18_RS12785	COG1175	transmembrane transport
HJX18_RS12800	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HJX18_RS12805	COG3383	formate dehydrogenase (NAD+) activity
HJX18_RS12845	COG1126	abc transporter atp-binding protein
HJX18_RS12850	COG0765	amino acid transport
HJX18_RS12870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJX18_RS12875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJX18_RS12880	COG1120	ATPase activity
HJX18_RS12885	COG4774	siderophore transport
HJX18_RS12890	COG1116	anion transmembrane transporter activity
HJX18_RS12895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HJX18_RS12915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJX18_RS12920	COG0583	DNA-binding transcription factor activity
HJX18_RS12940	COG2814	Major facilitator Superfamily
HJX18_RS12975	COG1414	Transcriptional regulator
HJX18_RS13000	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HJX18_RS13005	COG2271	Major facilitator Superfamily
HJX18_RS13015	COG1309	transcriptional regulator
HJX18_RS13045	COG1376	ErfK ybiS ycfS ynhG family protein
HJX18_RS13060	COG0719	Fe-S assembly protein
HJX18_RS13065	COG0396	ATPase activity
HJX18_RS13070	COG0719	Fe-S assembly protein
HJX18_RS13075	COG0316	Belongs to the HesB IscA family
HJX18_RS13095	COG1309	transcriptional regulator
HJX18_RS13100	COG1304	FMN binding
HJX18_RS13125	COG0583	DNA-binding transcription factor activity
HJX18_RS13135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJX18_RS13140	COG1120	ATPase activity
HJX18_RS13165	COG2261	transglycosylase associated protein
HJX18_RS13170	COG2050	protein possibly involved in aromatic compounds catabolism
HJX18_RS13175	COG0247	lactate metabolic process
HJX18_RS13175	COG0277	FAD linked oxidase domain protein
HJX18_RS13180	COG0628	permease
HJX18_RS13190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HJX18_RS13190	COG0574	Belongs to the PEP-utilizing enzyme family
HJX18_RS13205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HJX18_RS13210	COG4256	Hemin uptake protein
HJX18_RS13220	COG0791	NLP P60 protein
HJX18_RS13230	COG0386	Belongs to the glutathione peroxidase family
HJX18_RS13250	COG0583	DNA-binding transcription factor activity
HJX18_RS13270	COG0072	phenylalanine-tRNA ligase activity
HJX18_RS13270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HJX18_RS13310	COG3137	Salt-induced outer membrane protein
HJX18_RS13315	COG1105	Belongs to the carbohydrate kinase PfkB family
HJX18_RS13325	COG3001	Fructosamine kinase
HJX18_RS13335	COG2350	Protein conserved in bacteria
HJX18_RS13345	COG2353	YceI-like domain
HJX18_RS13365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HJX18_RS13375	COG0444	Belongs to the ABC transporter superfamily
HJX18_RS13380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HJX18_RS13385	COG0601	transmembrane transport
HJX18_RS13390	COG4166	transmembrane transport
HJX18_RS13400	COG2095	MarC family integral membrane protein
HJX18_RS13410	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS13410	COG1454	alcohol dehydrogenase
HJX18_RS13415	COG1435	thymidine kinase activity
HJX18_RS13425	COG2916	Histone family protein nucleoid-structuring protein H-NS
HJX18_RS13430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HJX18_RS13435	COG0745	RESPONSE REGULATOR receiver
HJX18_RS13440	COG1752	Esterase of the alpha-beta hydrolase superfamily
HJX18_RS13450	COG0788	formyltetrahydrofolate deformylase activity
HJX18_RS13480	COG1522	sequence-specific DNA binding
HJX18_RS13490	COG2181	nitrate reductase activity
HJX18_RS13495	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HJX18_RS13500	COG1140	nitrate reductase beta subunit
HJX18_RS13505	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HJX18_RS13515	COG2223	nitrite transmembrane transporter activity
HJX18_RS13520	COG3850	Histidine kinase
HJX18_RS13525	COG2197	response regulator
HJX18_RS13530	COG4932	domain protein
HJX18_RS13535	COG0243	molybdopterin cofactor binding
HJX18_RS13540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HJX18_RS13540	COG2146	nitrite reductase [NAD(P)H] activity
HJX18_RS13545	COG1116	anion transmembrane transporter activity
HJX18_RS13555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HJX18_RS13565	COG3707	response regulator
HJX18_RS13570	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HJX18_RS13580	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HJX18_RS13585	COG4572	Cation transport regulator
HJX18_RS13590	COG0387	Pfam Sodium calcium exchanger
HJX18_RS13610	COG2890	protein-(glutamine-N5) methyltransferase activity
HJX18_RS13640	COG0659	secondary active sulfate transmembrane transporter activity
HJX18_RS13660	COG0012	GTP binding
HJX18_RS13725	COG1388	LysM domain
HJX18_RS13730	COG3501	Rhs element vgr protein
HJX18_RS13740	COG2885	chlorophyll binding
HJX18_RS13765	COG3122	Protein conserved in bacteria
HJX18_RS13780	COG0583	DNA-binding transcription factor activity
HJX18_RS13810	COG0583	DNA-binding transcription factor activity
HJX18_RS13845	COG1882	Formate acetyltransferase
HJX18_RS13860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HJX18_RS13865	COG0583	DNA-binding transcription factor activity
HJX18_RS13905	COG2308	Evidence 4 Homologs of previously reported genes of
HJX18_RS13915	COG2211	Major facilitator Superfamily
HJX18_RS13925	COG4774	siderophore transport
HJX18_RS13935	COG1619	proteins homologs of microcin C7 resistance protein MccF
HJX18_RS13960	COG2719	SpoVR family
HJX18_RS13990	COG0179	Fumarylacetoacetate (FAA) hydrolase
HJX18_RS14005	COG2894	cell division
HJX18_RS14015	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HJX18_RS14025	COG3065	identical protein binding
HJX18_RS14035	COG1199	ATP-dependent helicase activity
HJX18_RS14040	COG0251	oxidation-reduction process
HJX18_RS14060	COG1760	l-serine dehydratase
HJX18_RS14070	COG2200	EAL domain
HJX18_RS14075	COG1253	flavin adenine dinucleotide binding
HJX18_RS14080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJX18_RS14080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJX18_RS14085	COG3715	PTS system
HJX18_RS14090	COG3716	PTS system mannose fructose sorbose family IID component
HJX18_RS14105	COG2226	methyltransferase
HJX18_RS14110	COG0768	penicillin binding
HJX18_RS14145	COG1414	Transcriptional regulator
HJX18_RS14150	COG2814	Major facilitator Superfamily
HJX18_RS14170	COG1956	GAF domain-containing protein
HJX18_RS14175	COG2995	paraquat-inducible protein a
HJX18_RS14180	COG3008	intermembrane lipid transfer
HJX18_RS14205	COG2990	Protein conserved in bacteria
HJX18_RS14220	COG1276	copper resistance
HJX18_RS14225	COG2372	response to copper ion
HJX18_RS14235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HJX18_RS14240	COG1770	oligopeptidase
HJX18_RS14245	COG2979	Protein of unknown function (DUF533)
HJX18_RS14250	COG3141	response to X-ray
HJX18_RS14260	COG0800	Aldolase
HJX18_RS14265	COG0129	dihydroxy-acid dehydratase activity
HJX18_RS14270	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HJX18_RS14280	COG1737	Transcriptional regulator
HJX18_RS14290	COG1560	Kdo2-lipid A biosynthetic process
HJX18_RS14295	COG0739	heme binding
HJX18_RS14300	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HJX18_RS14310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HJX18_RS14335	COG0494	nUDIX hydrolase
HJX18_RS14345	COG1335	isochorismatase
HJX18_RS14350	COG1801	Protein of unknown function DUF72
HJX18_RS14355	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HJX18_RS14375	COG3102	Protein conserved in bacteria
HJX18_RS14385	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HJX18_RS14410	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS14420	COG1879	ABC-type sugar transport system periplasmic component
HJX18_RS14430	COG1528	Iron-storage protein
HJX18_RS14440	COG2211	Major facilitator Superfamily
HJX18_RS14450	COG0477	Major facilitator Superfamily
HJX18_RS14465	COG1528	Iron-storage protein
HJX18_RS14475	COG0814	amino acid
HJX18_RS14480	COG3012	SEC-C Motif Domain Protein
HJX18_RS14480	COG3318	Belongs to the UPF0149 family
HJX18_RS14515	COG2197	response regulator
HJX18_RS14525	COG2197	response regulator
HJX18_RS14550	COG0366	Alpha amylase catalytic
HJX18_RS14580	COG2354	Protein conserved in bacteria
HJX18_RS14585	COG0697	spore germination
HJX18_RS14590	COG3727	T/G mismatch-specific endonuclease activity
HJX18_RS14595	COG0270	DNA (cytosine-5-)-methyltransferase activity
HJX18_RS14600	COG1418	mRNA catabolic process
HJX18_RS14615	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HJX18_RS14670	COG0025	NhaP-type Na H and K H
HJX18_RS14675	COG1309	transcriptional regulator
HJX18_RS14680	COG0604	alcohol dehydrogenase
HJX18_RS14700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HJX18_RS14710	COG0534	Mate efflux family protein
HJX18_RS14725	COG0582	viral genome integration into host DNA
HJX18_RS14740	COG1737	Transcriptional regulator
HJX18_RS14755	COG2814	Major facilitator Superfamily
HJX18_RS14760	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS14775	COG4977	sequence-specific DNA binding
HJX18_RS14780	COG1566	PFAM secretion protein HlyD family protein
HJX18_RS14795	COG2207	Transcriptional regulator
HJX18_RS14815	COG3706	GGDEF domain
HJX18_RS14840	COG3615	Tellurite resistance protein tehB
HJX18_RS14850	COG3300	MHYT domain
HJX18_RS14850	COG5001	Diguanylate cyclase
HJX18_RS14860	COG0477	Major facilitator Superfamily
HJX18_RS14865	COG0095	Lipoate-protein ligase
HJX18_RS14870	COG0583	DNA-binding transcription factor activity
HJX18_RS14875	COG1942	4-Oxalocrotonate Tautomerase
HJX18_RS14885	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HJX18_RS14905	COG1289	transmembrane transporter activity
HJX18_RS14920	COG2925	Exonuclease
HJX18_RS14925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HJX18_RS14930	COG0640	Transcriptional regulator
HJX18_RS14935	COG0531	amino acid
HJX18_RS14945	COG0583	DNA-binding transcription factor activity
HJX18_RS14950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HJX18_RS14980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HJX18_RS15005	COG0463	Glycosyl transferase, family 2
HJX18_RS15015	COG1216	Glycosyl transferase, family 2
HJX18_RS15015	COG1442	glycosyl transferase family 8
HJX18_RS15020	COG0438	transferase activity, transferring glycosyl groups
HJX18_RS15155	COG1253	flavin adenine dinucleotide binding
HJX18_RS15160	COG2982	Protein involved in outer membrane biogenesis
HJX18_RS15175	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HJX18_RS15180	COG0443	Heat shock 70 kDa protein
HJX18_RS15185	COG5002	protein histidine kinase activity
HJX18_RS15205	COG1301	dicarboxylic acid transport
HJX18_RS15230	COG2205	protein histidine kinase activity
HJX18_RS15235	COG0745	RESPONSE REGULATOR receiver
HJX18_RS15250	COG4608	Belongs to the ABC transporter superfamily
HJX18_RS15255	COG0444	Belongs to the ABC transporter superfamily
HJX18_RS15265	COG0601	transmembrane transport
HJX18_RS15270	COG0747	negative chemotaxis
HJX18_RS15275	COG4948	Mandelate Racemase Muconate Lactonizing
HJX18_RS15280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HJX18_RS15290	COG1070	Carbohydrate kinase
HJX18_RS15315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HJX18_RS15325	COG1830	Aldolase
HJX18_RS15330	COG0351	phosphomethylpyrimidine kinase
HJX18_RS15345	COG0583	DNA-binding transcription factor activity
HJX18_RS15355	COG2252	PERMEase
HJX18_RS15360	COG0583	DNA-binding transcription factor activity
HJX18_RS15365	COG5455	response to cobalt ion
HJX18_RS15385	COG4807	Protein conserved in bacteria
HJX18_RS15395	COG3275	phosphorelay sensor kinase activity
HJX18_RS15405	COG1174	glycine betaine transport
HJX18_RS15410	COG1125	glycine betaine transport
HJX18_RS15415	COG1174	glycine betaine transport
HJX18_RS15420	COG1732	Glycine betaine
HJX18_RS15425	COG1472	Belongs to the glycosyl hydrolase 3 family
HJX18_RS15430	COG0277	FAD linked oxidase domain protein
HJX18_RS15440	COG1686	Belongs to the peptidase S11 family
HJX18_RS15450	COG0586	Pfam SNARE associated Golgi protein
HJX18_RS15455	COG1538	Outer membrane efflux protein
HJX18_RS15460	COG2723	6-phospho-beta-galactosidase activity
HJX18_RS15475	COG3659	wide pore channel activity
HJX18_RS15480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HJX18_RS15490	COG1346	cytolysis
HJX18_RS15500	COG2949	membrane
HJX18_RS15510	COG1129	ABC transporter
HJX18_RS15525	COG2311	Membrane
HJX18_RS15540	COG4771	TonB-dependent receptor
HJX18_RS15545	COG0833	amino acid
HJX18_RS15550	COG0583	DNA-binding transcription factor activity
HJX18_RS15555	COG2855	membrane
HJX18_RS15565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJX18_RS15565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HJX18_RS15565	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HJX18_RS15570	COG1105	Belongs to the carbohydrate kinase PfkB family
HJX18_RS15575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJX18_RS15575	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJX18_RS15595	COG1312	Catalyzes the dehydration of D-mannonate
HJX18_RS15600	COG0246	Mannitol dehydrogenase
HJX18_RS15605	COG0523	cobalamin synthesis protein
HJX18_RS15610	COG0671	phosphoesterase, PA-phosphatase related
HJX18_RS15615	COG0791	NLP P60 protein
HJX18_RS15620	COG2200	EAL domain
HJX18_RS15625	COG4166	transmembrane transport
HJX18_RS15630	COG4174	ABC transporter (Permease)
HJX18_RS15635	COG4239	(ABC) transporter, permease
HJX18_RS15640	COG4172	Belongs to the ABC transporter superfamily
HJX18_RS15650	COG2814	Major facilitator Superfamily
HJX18_RS15655	COG1187	pseudouridine synthase activity
HJX18_RS15660	COG1061	Type III restriction enzyme res subunit
HJX18_RS15680	COG0494	nUDIX hydrolase
HJX18_RS15685	COG1349	DNA-binding transcription factor activity
HJX18_RS15710	COG0628	permease
HJX18_RS15725	COG0659	secondary active sulfate transmembrane transporter activity
HJX18_RS15730	COG2239	Acts as a magnesium transporter
HJX18_RS15735	COG4615	Cyclic peptide transporter
HJX18_RS15740	COG3145	DNA-N1-methyladenine dioxygenase activity
HJX18_RS15745	COG2169	Transcriptional regulator
HJX18_RS15745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HJX18_RS15760	COG2198	Histidine kinase
HJX18_RS15760	COG0642	Histidine kinase
HJX18_RS15770	COG0784	Response regulator, receiver
HJX18_RS15770	COG2205	protein histidine kinase activity
HJX18_RS15775	COG3852	Histidine kinase
HJX18_RS15780	COG2204	response regulator
HJX18_RS15790	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HJX18_RS15795	COG2031	fatty acid transporter
HJX18_RS15800	COG0183	Belongs to the thiolase family
HJX18_RS15825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HJX18_RS15830	COG0584	glycerophosphoryl diester phosphodiesterase
HJX18_RS15835	COG2271	Major facilitator Superfamily
HJX18_RS15840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HJX18_RS15850	COG0247	lactate metabolic process
HJX18_RS15860	COG2271	Major facilitator Superfamily
HJX18_RS15870	COG3344	reverse transcriptase
HJX18_RS15880	COG1414	Transcriptional regulator
HJX18_RS15900	COG5464	transposase or invertase
HJX18_RS15910	COG0318	PFAM AMP-dependent synthetase and ligase
HJX18_RS15935	COG1169	isochorismate synthase
HJX18_RS15940	COG2153	protein acetylation
HJX18_RS15955	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HJX18_RS15960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HJX18_RS15970	COG0839	Belongs to the complex I subunit 6 family
HJX18_RS16020	COG0583	DNA-binding transcription factor activity
HJX18_RS16025	COG0436	Aminotransferase
HJX18_RS16035	COG0471	metal ion transport
HJX18_RS16035	COG0490	domain, Protein
HJX18_RS16040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HJX18_RS16060	COG0857	belongs to the CobB CobQ family
HJX18_RS16060	COG0280	phosphate acetyltransferase
HJX18_RS16065	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HJX18_RS16070	COG0622	Phosphoesterase
HJX18_RS16075	COG0625	glutathione transferase activity
HJX18_RS16080	COG0625	glutathione transferase activity
HJX18_RS16085	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HJX18_RS16090	COG1090	epimerase
HJX18_RS16105	COG4598	ABC transporter
HJX18_RS16110	COG4160	amino acid transport
HJX18_RS16135	COG0163	prenyltransferase activity
HJX18_RS16140	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HJX18_RS16145	COG1286	toxin biosynthetic process
HJX18_RS16150	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HJX18_RS16155	COG0285	dihydrofolate synthase activity
HJX18_RS16165	COG0586	Pfam SNARE associated Golgi protein
HJX18_RS16175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HJX18_RS16195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HJX18_RS16210	COG3101	peptidyl-lysine hydroxylation
HJX18_RS16215	COG0730	response to heat
HJX18_RS16240	COG2062	phosphohistidine phosphatase, SixA
HJX18_RS16255	COG3691	Protein conserved in bacteria
HJX18_RS16265	COG2853	Lipoprotein
HJX18_RS16270	COG2116	formate transmembrane transporter activity
HJX18_RS16290	COG0583	DNA-binding transcription factor activity
HJX18_RS16295	COG0590	tRNA wobble adenosine to inosine editing
HJX18_RS16300	COG2807	transmembrane transport
HJX18_RS16310	COG0436	Aminotransferase
HJX18_RS16325	COG3275	phosphorelay sensor kinase activity
HJX18_RS16330	COG3279	Response regulator of the LytR AlgR family
HJX18_RS16345	COG3961	Belongs to the TPP enzyme family
HJX18_RS16350	COG0667	Aldo Keto reductase
HJX18_RS16365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HJX18_RS16370	COG2200	EAL domain
HJX18_RS16370	COG2199	diguanylate cyclase activity
HJX18_RS16385	COG3415	Transposase
HJX18_RS16390	COG3415	Transposase
HJX18_RS16420	COG0583	DNA-binding transcription factor activity
HJX18_RS16425	COG0385	Bile acid
HJX18_RS16430	COG3530	Putative quorum-sensing-regulated virulence factor
HJX18_RS16450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HJX18_RS16490	COG4319	ketosteroid isomerase
HJX18_RS16505	COG4208	sulfate ABC transporter
HJX18_RS16510	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HJX18_RS16515	COG4150	thiosulfate binding
HJX18_RS16525	COG2837	iron assimilation
HJX18_RS16545	COG0860	N-Acetylmuramoyl-L-alanine amidase
HJX18_RS16635	COG4810	utilization protein
HJX18_RS16645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HJX18_RS16650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HJX18_RS16655	COG5342	invasion associated locus B
HJX18_RS16665	COG0493	'glutamate synthase
HJX18_RS16665	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HJX18_RS16670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJX18_RS16680	COG1393	Belongs to the ArsC family
HJX18_RS16695	COG0400	carboxylic ester hydrolase activity
HJX18_RS16700	COG1444	tRNA N-acetyltransferase activity
HJX18_RS16705	COG2321	neutral zinc metallopeptidase
HJX18_RS16715	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HJX18_RS16725	COG2716	regulation of RNA biosynthetic process
HJX18_RS16730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HJX18_RS16735	COG0628	permease
HJX18_RS16745	COG4783	chaperone-mediated protein folding
HJX18_RS16750	COG1393	Belongs to the ArsC family
HJX18_RS16765	COG2233	PERMEase
HJX18_RS16775	COG2723	6-phospho-beta-galactosidase activity
HJX18_RS16790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HJX18_RS16805	COG2200	EAL domain
HJX18_RS16825	COG0641	radical SAM
HJX18_RS16830	COG3119	arylsulfatase activity
HJX18_RS16840	COG0516	GMP reductase activity
HJX18_RS16840	COG0517	IMP dehydrogenase activity
HJX18_RS16850	COG1645	bacterial-type flagellum-dependent swarming motility
HJX18_RS16870	COG2976	Protein conserved in bacteria
HJX18_RS16900	COG4953	penicillin-binding protein 1C
HJX18_RS16905	COG2373	Large extracellular alpha-helical protein
HJX18_RS16910	COG2897	thiosulfate sulfurtransferase activity
HJX18_RS16930	COG2975	iron-sulfur cluster assembly
HJX18_RS16935	COG0633	Ferredoxin
HJX18_RS16955	COG0822	iron-sulfur transferase activity
HJX18_RS16985	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HJX18_RS16990	COG3683	transport system, periplasmic component
HJX18_RS16995	COG3711	transcriptional antiterminator
HJX18_RS17000	COG2814	Major facilitator Superfamily
HJX18_RS17005	COG2017	converts alpha-aldose to the beta-anomer
HJX18_RS17010	COG2814	Major facilitator Superfamily
HJX18_RS17010	COG0477	Major facilitator Superfamily
HJX18_RS17015	COG0457	Tetratricopeptide repeat
HJX18_RS17020	COG1940	carbohydrate kinase activity
HJX18_RS17025	COG2259	Doxx family
HJX18_RS17035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HJX18_RS17035	COG1017	nitric oxide dioxygenase activity
HJX18_RS17040	COG0347	Belongs to the P(II) protein family
HJX18_RS17045	COG2204	response regulator
HJX18_RS17050	COG3170	Tfp pilus assembly protein FimV
HJX18_RS17055	COG2205	protein histidine kinase activity
HJX18_RS17060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HJX18_RS17060	COG0047	phosphoribosylformylglycinamidine synthase activity
HJX18_RS17075	COG0560	Phosphoserine phosphatase
HJX18_RS17080	COG1737	Transcriptional regulator
HJX18_RS17085	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HJX18_RS17095	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HJX18_RS17115	COG0681	Belongs to the peptidase S26 family
HJX18_RS17125	COG3086	response to oxidative stress
HJX18_RS17130	COG3026	antisigma factor binding
HJX18_RS17135	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HJX18_RS17150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HJX18_RS17160	COG0513	Belongs to the DEAD box helicase family
HJX18_RS17175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HJX18_RS17180	COG3118	belongs to the thioredoxin family
HJX18_RS17195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HJX18_RS17200	COG5544	Lipoprotein
HJX18_RS17205	COG0477	Major facilitator Superfamily
HJX18_RS17230	COG0542	response to heat
HJX18_RS17245	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HJX18_RS17250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HJX18_RS17260	COG1605	Chorismate mutase
HJX18_RS17260	COG0077	Prephenate dehydratase
HJX18_RS17270	COG0287	Prephenate dehydrogenase
HJX18_RS17270	COG1605	Chorismate mutase
HJX18_RS17275	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HJX18_RS17285	COG2199	diguanylate cyclase activity
HJX18_RS17290	COG2885	chlorophyll binding
HJX18_RS17330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HJX18_RS17335	COG4137	Cytochrome C assembly protein
HJX18_RS17340	COG4536	flavin adenine dinucleotide binding
HJX18_RS17355	COG0497	DNA recombination
HJX18_RS17375	COG2867	negative regulation of translational initiation
HJX18_RS17440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HJX18_RS17545	COG4695	Portal protein
HJX18_RS17580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HJX18_RS17615	COG4974	Belongs to the 'phage' integrase family
HJX18_RS17675	COG2207	Transcriptional regulator
HJX18_RS17675	COG3708	Transcriptional regulator
HJX18_RS17680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJX18_RS17715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJX18_RS17725	COG0235	Class ii aldolase
HJX18_RS17735	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS17770	COG3121	Chaperone
HJX18_RS17775	COG3539	Fimbrial protein
HJX18_RS17780	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS17785	COG3284	Transcriptional regulator
HJX18_RS17790	COG0583	DNA-binding transcription factor activity
HJX18_RS17800	COG0640	Transcriptional regulator
HJX18_RS17805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HJX18_RS17820	COG2916	Histone family protein nucleoid-structuring protein H-NS
HJX18_RS17840	COG4575	ribosome binding
HJX18_RS17845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HJX18_RS17850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HJX18_RS17855	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HJX18_RS17865	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HJX18_RS17880	COG4176	ABC-type proline glycine betaine transport system permease component
HJX18_RS17890	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HJX18_RS17905	COG1846	Transcriptional regulator
HJX18_RS17915	COG1566	PFAM secretion protein HlyD family protein
HJX18_RS17920	COG2814	Major facilitator Superfamily
HJX18_RS17925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HJX18_RS17945	COG1238	metal cluster binding
HJX18_RS17950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HJX18_RS17955	COG2823	Periplasmic or secreted lipoprotein
HJX18_RS17990	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HJX18_RS18010	COG1546	Belongs to the CinA family
HJX18_RS18020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HJX18_RS18025	COG1121	(ABC) transporter
HJX18_RS18030	COG2951	lytic endotransglycosylase activity
HJX18_RS18035	COG3730	PTS system glucitol sorbitol-specific
HJX18_RS18040	COG3732	PTS system glucitol sorbitol-specific
HJX18_RS18050	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS18055	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJX18_RS18060	COG1349	DNA-binding transcription factor activity
HJX18_RS18090	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HJX18_RS18095	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HJX18_RS18100	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HJX18_RS18105	COG1609	Transcriptional regulator
HJX18_RS18115	COG1263	PTS System
HJX18_RS18115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJX18_RS18120	COG2723	6-phospho-beta-galactosidase activity
HJX18_RS18130	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HJX18_RS18140	COG3260	NADH ubiquinone oxidoreductase 20
HJX18_RS18145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HJX18_RS18150	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HJX18_RS18150	COG3261	NADH dehydrogenase
HJX18_RS18155	COG0650	Formate hydrogenlyase subunit 4
HJX18_RS18160	COG0651	ATP synthesis coupled electron transport
HJX18_RS18165	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HJX18_RS18180	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HJX18_RS18185	COG0298	carbon dioxide binding
HJX18_RS18190	COG0409	Hydrogenase expression formation protein
HJX18_RS18195	COG0309	Hydrogenase expression formation protein (HypE)
HJX18_RS18205	COG2723	6-phospho-beta-galactosidase activity
HJX18_RS18215	COG4580	involved in the transport of maltose and maltodextrins
HJX18_RS18220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJX18_RS18225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJX18_RS18230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJX18_RS18235	COG1447	Phosphotransferase system cellobiose-specific component IIA
HJX18_RS18240	COG1940	carbohydrate kinase activity
HJX18_RS18245	COG1609	Transcriptional regulator
HJX18_RS18255	COG1121	(ABC) transporter
HJX18_RS18260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HJX18_RS18265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HJX18_RS18280	COG0679	Auxin Efflux Carrier
HJX18_RS18300	COG3720	iron ion transport
HJX18_RS18305	COG4558	Periplasmic binding protein
HJX18_RS18310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HJX18_RS18350	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HJX18_RS18355	COG0163	prenyltransferase activity
HJX18_RS18380	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HJX18_RS18385	COG4942	peptidase
HJX18_RS18385	COG1388	LysM domain
HJX18_RS18445	COG2234	aminopeptidase activity
HJX18_RS18465	COG0720	synthase
HJX18_RS18470	COG0602	queuosine metabolic process
HJX18_RS18495	COG3956	TIGRFAM MazG family protein
HJX18_RS18500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HJX18_RS18510	COG2205	protein histidine kinase activity
HJX18_RS18510	COG3850	Histidine kinase
HJX18_RS18510	COG4999	Histidine kinase
HJX18_RS18510	COG3437	response regulator, receiver
HJX18_RS18515	COG1929	Belongs to the glycerate kinase type-1 family
HJX18_RS18520	COG4948	Mandelate Racemase Muconate Lactonizing
HJX18_RS18525	COG4948	Mandelate Racemase Muconate Lactonizing
HJX18_RS18530	COG2271	Major facilitator Superfamily
HJX18_RS18535	COG0716	FMN binding
HJX18_RS18540	COG0564	pseudouridine synthase activity
HJX18_RS18545	COG3098	single-species biofilm formation
HJX18_RS18560	COG1611	Belongs to the LOG family
HJX18_RS18565	COG0814	amino acid
HJX18_RS18570	COG1760	l-serine dehydratase
HJX18_RS18575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HJX18_RS18585	COG0477	Major facilitator Superfamily
HJX18_RS18590	COG1464	Belongs to the NlpA lipoprotein family
HJX18_RS18600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HJX18_RS18615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJX18_RS18635	COG1454	alcohol dehydrogenase
HJX18_RS18640	COG0235	Class ii aldolase
HJX18_RS18650	COG0738	Major facilitator superfamily
HJX18_RS18670	COG1349	DNA-binding transcription factor activity
HJX18_RS18680	COG2363	Small membrane protein
HJX18_RS18685	COG0583	DNA-binding transcription factor activity
HJX18_RS18695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HJX18_RS18700	COG2166	iron-sulfur cluster assembly
HJX18_RS18705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HJX18_RS18710	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HJX18_RS18890	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HJX18_RS18905	COG1012	belongs to the aldehyde dehydrogenase family
HJX18_RS18905	COG1454	alcohol dehydrogenase
HJX18_RS18910	COG4656	Part of a membrane complex involved in electron transport
HJX18_RS18940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HJX18_RS18945	COG0860	N-Acetylmuramoyl-L-alanine amidase
HJX18_RS18950	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HJX18_RS18950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HJX18_RS18960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HJX18_RS18965	COG1074	ATP-dependent DNA helicase activity
HJX18_RS18970	COG1025	Belongs to the peptidase M16 family
HJX18_RS18975	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HJX18_RS18980	COG4967	type IV pilus modification protein PilV
HJX18_RS18990	COG4795	General secretion pathway protein
HJX18_RS18995	COG2165	general secretion pathway protein
HJX18_RS19030	COG0861	Integral membrane protein TerC family
HJX18_RS19040	COG0667	Aldo Keto reductase
HJX18_RS19055	COG1609	Transcriptional regulator
HJX18_RS19065	COG2186	Transcriptional regulator
HJX18_RS19070	COG2723	6-phospho-beta-galactosidase activity
HJX18_RS19075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJX18_RS19080	COG1609	Transcriptional regulator
HJX18_RS19090	COG0583	DNA-binding transcription factor activity
HJX18_RS19095	COG1794	racemase activity, acting on amino acids and derivatives
HJX18_RS19100	COG1917	Cupin 2, conserved barrel domain protein
HJX18_RS19105	COG1175	transmembrane transport
HJX18_RS19110	COG0395	ABC-type sugar transport system, permease component
HJX18_RS19115	COG3842	ATPase activity
HJX18_RS19150	COG2814	Major facilitator Superfamily
HJX18_RS19155	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS19165	COG0823	Involved in the tonB-independent uptake of proteins
HJX18_RS19175	COG0183	Belongs to the thiolase family
HJX18_RS19190	COG0814	amino acid
HJX18_RS19195	COG0667	Aldo Keto reductase
HJX18_RS19245	COG0697	spore germination
HJX18_RS19250	COG1846	Transcriptional regulator
HJX18_RS19255	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HJX18_RS19260	COG0582	viral genome integration into host DNA
HJX18_RS19265	COG4974	Belongs to the 'phage' integrase family
HJX18_RS19280	COG3539	Fimbrial protein
HJX18_RS19285	COG3121	Chaperone
HJX18_RS19290	COG3188	usher protein
HJX18_RS19295	COG3539	Fimbrial protein
HJX18_RS19300	COG3539	Fimbrial protein
HJX18_RS19305	COG3539	Fimbrial protein
HJX18_RS19315	COG2388	GCN5-related N-acetyl-transferase
HJX18_RS19320	COG3592	Divergent 4Fe-4S mono-cluster
HJX18_RS19335	COG1289	transmembrane transporter activity
HJX18_RS19340	COG1538	Outer membrane efflux protein
HJX18_RS19350	COG3104	oligopeptide transport
HJX18_RS19355	COG1393	Belongs to the ArsC family
HJX18_RS19360	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HJX18_RS19400	COG0667	Aldo Keto reductase
HJX18_RS19415	COG2200	EAL domain
HJX18_RS19435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJX18_RS19435	COG0784	Response regulator, receiver
HJX18_RS19435	COG2205	protein histidine kinase activity
HJX18_RS19435	COG2198	Histidine kinase
HJX18_RS19440	COG2197	response regulator
HJX18_RS19445	COG1566	PFAM secretion protein HlyD family protein
HJX18_RS19450	COG0477	Major facilitator Superfamily
HJX18_RS19465	COG0004	ammonium transporteR
HJX18_RS19470	COG0831	urea catabolic process
HJX18_RS19475	COG0832	Belongs to the urease beta subunit family
HJX18_RS19495	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HJX18_RS19505	COG4413	Urea transporter
HJX18_RS19515	COG0601	transmembrane transport
HJX18_RS19520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HJX18_RS19550	COG3188	usher protein
HJX18_RS19555	COG2197	response regulator
HJX18_RS19560	COG2205	protein histidine kinase activity
HJX18_RS19560	COG2198	Histidine kinase
HJX18_RS19560	COG0784	Response regulator, receiver
HJX18_RS19560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJX18_RS19570	COG2197	response regulator
HJX18_RS19595	COG2814	Major facilitator Superfamily
HJX18_RS19610	COG3646	Phage regulatory protein
HJX18_RS19620	COG4974	Belongs to the 'phage' integrase family
HJX18_RS19630	COG4942	peptidase
HJX18_RS19655	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HJX18_RS19665	COG4974	Belongs to the 'phage' integrase family
HJX18_RS19670	COG0716	FMN binding
HJX18_RS19680	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HJX18_RS19690	COG1272	protein, Hemolysin III
HJX18_RS19700	COG1737	Transcriptional regulator
HJX18_RS19705	COG2723	6-phospho-beta-galactosidase activity
HJX18_RS19725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HJX18_RS19735	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS19755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HJX18_RS19760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HJX18_RS19765	COG0006	proline dipeptidase activity
HJX18_RS19785	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HJX18_RS19790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HJX18_RS19810	COG2968	Membrane
HJX18_RS19820	COG0668	transmembrane transport
HJX18_RS19825	COG0191	fructose-bisphosphate aldolase activity
HJX18_RS19840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HJX18_RS19845	COG0501	Belongs to the peptidase M48B family
HJX18_RS19880	COG2814	Major facilitator Superfamily
HJX18_RS19890	COG2356	endonuclease I
HJX18_RS19895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HJX18_RS19900	COG0189	ligase activity
HJX18_RS19925	COG2805	Type II/IV secretion system protein
HJX18_RS19930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HJX18_RS19935	COG0762	integral membrane protein
HJX18_RS19950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HJX18_RS19965	COG4214	carbohydrate transport
HJX18_RS19975	COG3171	Protein conserved in bacteria
HJX18_RS19985	COG1194	a g-specific adenine glycosylase
HJX18_RS20000	COG2211	Major facilitator Superfamily
HJX18_RS20005	COG1982	Orn Lys Arg decarboxylase major
HJX18_RS20010	COG1811	Na channel or pump
HJX18_RS20025	COG0582	viral genome integration into host DNA
HJX18_RS20040	COG3188	usher protein
HJX18_RS20045	COG3121	Chaperone
HJX18_RS20050	COG3121	Chaperone
HJX18_RS20065	COG3121	Chaperone
HJX18_RS20080	COG0626	cystathionine gamma-synthase activity
HJX18_RS20085	COG0583	DNA-binding transcription factor activity
HJX18_RS20105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HJX18_RS20110	COG0754	glutathionylspermidine amidase activity
HJX18_RS20125	COG0625	glutathione transferase activity
HJX18_RS20145	COG0848	biopolymer transport protein
HJX18_RS20160	COG0626	cystathionine gamma-synthase activity
HJX18_RS20165	COG0586	Pfam SNARE associated Golgi protein
HJX18_RS20170	COG2207	Transcriptional regulator
HJX18_RS20175	COG1979	alcohol dehydrogenase
HJX18_RS20180	COG0656	L-ascorbic acid biosynthetic process
HJX18_RS20190	COG1032	radical SAM domain protein
HJX18_RS20195	COG2132	Multicopper oxidase
HJX18_RS20200	COG0204	Acyl-transferase
HJX18_RS20205	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HJX18_RS20210	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HJX18_RS20215	COG3111	PFAM Bacterial OB fold (BOF) protein
HJX18_RS20225	COG0642	Histidine kinase
HJX18_RS20230	COG2249	NAD(P)H dehydrogenase (quinone) activity
HJX18_RS20235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HJX18_RS20245	COG3150	esterase
HJX18_RS20250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HJX18_RS20255	COG3151	Protein conserved in bacteria
HJX18_RS20260	COG0494	nUDIX hydrolase
HJX18_RS20275	COG0754	glutathionylspermidine amidase activity
HJX18_RS20280	COG3384	dioxygenase
HJX18_RS20295	COG2960	long-chain fatty acid transporting porin activity
HJX18_RS20320	COG3025	triphosphatase activity
HJX18_RS20325	COG4991	sh3 domain protein
HJX18_RS20340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HJX18_RS20405	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HJX18_RS20410	COG0358	DNA primase activity
HJX18_RS20415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HJX18_RS20440	COG2197	response regulator
HJX18_RS20445	COG0784	Response regulator, receiver
HJX18_RS20445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJX18_RS20445	COG2198	Histidine kinase
HJX18_RS20445	COG2205	protein histidine kinase activity
HJX18_RS20455	COG3247	response to pH
HJX18_RS20525	COG2376	Dihydroxyacetone kinase
HJX18_RS20530	COG1461	Dihydroxyacetone kinase
HJX18_RS20545	COG2375	cellular response to nickel ion
HJX18_RS20555	COG1695	Transcriptional regulator
HJX18_RS20565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HJX18_RS20570	COG1609	Transcriptional regulator
HJX18_RS20575	COG3250	beta-galactosidase activity
HJX18_RS20580	COG2731	YhcH YjgK YiaL family protein
HJX18_RS20585	COG0531	amino acid
HJX18_RS20590	COG0531	amino acid
HJX18_RS20600	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HJX18_RS20600	COG3408	Glycogen debranching enzyme
HJX18_RS20645	COG1902	pentaerythritol trinitrate reductase activity
HJX18_RS20645	COG0446	pyridine nucleotide-disulphide oxidoreductase
HJX18_RS20665	COG1451	nucleotide metabolic process
HJX18_RS20670	COG0673	inositol 2-dehydrogenase activity
HJX18_RS20675	COG0861	Integral membrane protein TerC family
HJX18_RS20690	COG2721	sulfolactate sulfo-lyase activity
HJX18_RS20700	COG2271	Major facilitator Superfamily
HJX18_RS20705	COG2186	Transcriptional regulator
HJX18_RS20710	COG0586	Pfam SNARE associated Golgi protein
HJX18_RS20720	COG1422	Protein of unknown function (DUF1090)
HJX18_RS20725	COG4575	ribosome binding
HJX18_RS20730	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HJX18_RS20740	COG2259	Doxx family
HJX18_RS20745	COG0435	Glutathione S-transferase
HJX18_RS20750	COG3152	Membrane
HJX18_RS20755	COG0583	DNA-binding transcription factor activity
HJX18_RS20760	COG1741	Belongs to the pirin family
HJX18_RS20790	COG1929	Belongs to the glycerate kinase type-1 family
HJX18_RS20795	COG2084	Dehydrogenase
HJX18_RS20805	COG2271	Major facilitator Superfamily
HJX18_RS20815	COG2721	sulfolactate sulfo-lyase activity
HJX18_RS20820	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HJX18_RS20840	COG2823	Periplasmic or secreted lipoprotein
HJX18_RS20845	COG0701	Predicted permease
HJX18_RS20850	COG0702	epimerase
HJX18_RS20855	COG0693	protein deglycase activity
HJX18_RS20870	COG3153	acetyltransferase
HJX18_RS20875	COG3154	lipid carrier protein
HJX18_RS20880	COG0826	peptidase U32
HJX18_RS20885	COG0826	peptidase U32
HJX18_RS20890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HJX18_RS20895	COG0814	amino acid
HJX18_RS20940	COG0195	Participates in both transcription termination and antitermination
HJX18_RS20985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HJX18_RS20995	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HJX18_RS21000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HJX18_RS21010	COG1534	Rna-binding protein
HJX18_RS21020	COG2027	D-alanyl-D-alanine carboxypeptidase
HJX18_RS21030	COG0697	spore germination
HJX18_RS21045	COG0142	geranyltranstransferase activity
HJX18_RS21050	COG3423	Transcriptional regulator
HJX18_RS21060	COG5007	Belongs to the BolA IbaG family
HJX18_RS21065	COG3113	response to antibiotic
HJX18_RS21070	COG2854	intermembrane phospholipid transfer
HJX18_RS21075	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HJX18_RS21080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HJX18_RS21085	COG1127	ABC transporter
HJX18_RS21090	COG0530	calcium, potassium:sodium antiporter activity
HJX18_RS21100	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HJX18_RS21105	COG3117	lipopolysaccharide transmembrane transporter activity
HJX18_RS21110	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HJX18_RS21115	COG1137	ATPase activity
HJX18_RS21120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HJX18_RS21125	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HJX18_RS21130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJX18_RS21140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJX18_RS21145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HJX18_RS21150	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HJX18_RS21155	COG2198	Histidine kinase
HJX18_RS21155	COG0784	Response regulator, receiver
HJX18_RS21155	COG5002	protein histidine kinase activity
HJX18_RS21160	COG1312	Catalyzes the dehydration of D-mannonate
HJX18_RS21170	COG1063	alcohol dehydrogenase
HJX18_RS21175	COG2271	Major facilitator Superfamily
HJX18_RS21180	COG1242	4 iron, 4 sulfur cluster binding
HJX18_RS21185	COG0067	glutamate synthase
HJX18_RS21185	COG0069	glutamate synthase activity
HJX18_RS21185	COG0070	glutamate synthase
HJX18_RS21190	COG0493	'glutamate synthase
HJX18_RS21200	COG2969	positive regulation of protein catabolic process
HJX18_RS21205	COG0625	glutathione transferase activity
HJX18_RS21225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HJX18_RS21230	COG3105	Protein conserved in bacteria
HJX18_RS21235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HJX18_RS21240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HJX18_RS21265	COG2732	(Barnase) inhibitor
HJX18_RS21270	COG1289	transmembrane transporter activity
HJX18_RS21285	COG0583	DNA-binding transcription factor activity
HJX18_RS21290	COG0312	modulator of DNA gyrase
HJX18_RS21295	COG3164	Protein of unknown function
HJX18_RS21300	COG1530	ribonuclease E activity
HJX18_RS21310	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HJX18_RS21315	COG1792	Involved in formation and maintenance of cell shape
HJX18_RS21320	COG1077	Cell shape determining protein MreB Mrl
HJX18_RS21325	COG2200	EAL domain
HJX18_RS21325	COG2199	diguanylate cyclase activity
HJX18_RS21350	COG0511	ligase activity, forming carbon-carbon bonds
HJX18_RS21355	COG0439	Biotin carboxylase
HJX18_RS21360	COG3924	membrane
HJX18_RS21365	COG4145	pantothenate transmembrane transporter activity
HJX18_RS21385	COG1309	transcriptional regulator
HJX18_RS21390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJX18_RS21395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJX18_RS21430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HJX18_RS21450	COG0551	DNA topoisomerase type I activity
HJX18_RS21460	COG0758	DNA mediated transformation
HJX18_RS21490	COG3036	rescue of stalled ribosome
HJX18_RS21495	COG0789	Transcriptional regulator
HJX18_RS21510	COG0202	RNA polymerase activity
HJX18_RS21535	COG0201	protein transport
HJX18_RS21600	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HJX18_RS21615	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HJX18_RS21640	COG0051	transcription antitermination factor activity, RNA binding
HJX18_RS21695	COG2964	Protein conserved in bacteria
HJX18_RS21700	COG0545	Peptidyl-prolyl cis-trans isomerase
HJX18_RS21710	COG1047	Peptidyl-prolyl cis-trans
HJX18_RS21715	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HJX18_RS21730	COG0488	(ABC) transporter
HJX18_RS21740	COG0429	hydrolase of the alpha beta-hydrolase fold
HJX18_RS21750	COG3954	Phosphoribulokinase
HJX18_RS21755	COG1765	OsmC-like protein
HJX18_RS21765	COG1289	transmembrane transporter activity
HJX18_RS21770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HJX18_RS21795	COG0738	Major facilitator superfamily
HJX18_RS21800	COG0402	S-adenosylhomocysteine deaminase activity
HJX18_RS21810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HJX18_RS21835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HJX18_RS21840	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HJX18_RS21845	COG3266	domain, Protein
HJX18_RS21860	COG4796	Type ii and iii secretion system protein
HJX18_RS21885	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HJX18_RS21890	COG0494	nUDIX hydrolase
HJX18_RS21900	COG1011	Hydrolase
HJX18_RS21905	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HJX18_RS21925	COG0745	RESPONSE REGULATOR receiver
HJX18_RS21930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HJX18_RS21935	COG2183	response to ionizing radiation
HJX18_RS21940	COG1918	ferrous iron import across plasma membrane
HJX18_RS21965	COG1040	competence protein
HJX18_RS21975	COG2610	gluconate transmembrane transporter activity
HJX18_RS21980	COG1640	4-alpha-glucanotransferase
HJX18_RS21985	COG0058	SHG alpha-glucan phosphorylase activity
HJX18_RS21995	COG1349	DNA-binding transcription factor activity
HJX18_RS22010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HJX18_RS22015	COG0058	SHG alpha-glucan phosphorylase activity
HJX18_RS22040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HJX18_RS22050	COG2610	gluconate transmembrane transporter activity
HJX18_RS22055	COG3265	gluconokinase activity
HJX18_RS22060	COG1609	Transcriptional regulator
HJX18_RS22065	COG1741	Belongs to the pirin family
HJX18_RS22070	COG0673	inositol 2-dehydrogenase activity
HJX18_RS22080	COG1247	-acetyltransferase
HJX18_RS22085	COG0405	Gamma-glutamyltransferase
HJX18_RS22095	COG0584	glycerophosphoryl diester phosphodiesterase
HJX18_RS22145	COG0559	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS22150	COG0683	leucine binding
HJX18_RS22160	COG0683	leucine binding
HJX18_RS22170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HJX18_RS22185	COG2177	Part of the ABC transporter FtsEX involved in
HJX18_RS22190	COG2884	Cell division ATP-binding protein ftsE
HJX18_RS22195	COG0552	protein localization to endoplasmic reticulum
HJX18_RS22200	COG0742	ribosomal rna small subunit methyltransferase
HJX18_RS22205	COG3776	membrane
HJX18_RS22215	COG3714	YhhN family
HJX18_RS22230	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HJX18_RS22240	COG0477	Major facilitator Superfamily
HJX18_RS22245	COG0628	permease
HJX18_RS22285	COG3479	Phenolic acid decarboxylase
HJX18_RS22295	COG0747	negative chemotaxis
HJX18_RS22300	COG0601	transmembrane transport
HJX18_RS22305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HJX18_RS22315	COG1124	(ABC) transporter
HJX18_RS22330	COG2239	Acts as a magnesium transporter
HJX18_RS22335	COG2081	HI0933 family
HJX18_RS22340	COG0306	phosphate transporter
HJX18_RS22350	COG0589	response to stress
HJX18_RS22370	COG0671	phosphoesterase, PA-phosphatase related
HJX18_RS22375	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HJX18_RS22380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HJX18_RS22390	COG1454	alcohol dehydrogenase
HJX18_RS22400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HJX18_RS22405	COG1028	Short-chain dehydrogenase reductase Sdr
HJX18_RS22410	COG0583	DNA-binding transcription factor activity
HJX18_RS22415	COG1295	ribonuclease BN
HJX18_RS22420	COG0477	Major facilitator Superfamily
HJX18_RS22425	COG2982	Protein involved in outer membrane biogenesis
HJX18_RS22440	COG0612	Peptidase, M16
HJX18_RS22450	COG2200	EAL domain
HJX18_RS22450	COG2199	diguanylate cyclase activity
HJX18_RS22455	COG0457	Tetratricopeptide repeat
HJX18_RS22455	COG3118	belongs to the thioredoxin family
HJX18_RS22460	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HJX18_RS22465	COG1215	transferase activity, transferring glycosyl groups
HJX18_RS22495	COG2194	sulfuric ester hydrolase activity
HJX18_RS22510	COG0457	Tetratricopeptide repeat
HJX18_RS22515	COG1215	transferase activity, transferring glycosyl groups
HJX18_RS22525	COG2894	cell division
HJX18_RS22540	COG4608	Belongs to the ABC transporter superfamily
HJX18_RS22545	COG0444	Belongs to the ABC transporter superfamily
HJX18_RS22550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HJX18_RS22555	COG0601	transmembrane transport
HJX18_RS22560	COG0747	negative chemotaxis
HJX18_RS22590	COG2223	nitrite transmembrane transporter activity
HJX18_RS22595	COG5571	outer membrane autotransporter
HJX18_RS22600	COG2818	Glycosylase
HJX18_RS22605	COG0456	acetyltransferase
HJX18_RS22610	COG0243	molybdopterin cofactor binding
HJX18_RS22615	COG2885	chlorophyll binding
HJX18_RS22625	COG1609	Transcriptional regulator
HJX18_RS22635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJX18_RS22655	COG2814	Major facilitator Superfamily
HJX18_RS22660	COG2944	sequence-specific DNA binding
HJX18_RS22665	COG1278	Cold shock
HJX18_RS22715	COG3274	enterobacterial common antigen metabolic process
HJX18_RS22720	COG4682	membrane
HJX18_RS22725	COG4682	membrane
HJX18_RS22740	COG4213	ABC transporter substrate-binding protein
HJX18_RS22750	COG4214	carbohydrate transport
HJX18_RS22755	COG1609	Transcriptional regulator
HJX18_RS22755	COG2207	Transcriptional regulator
HJX18_RS22760	COG2992	FlgJ-related protein
HJX18_RS22765	COG0366	Alpha amylase catalytic
HJX18_RS22770	COG3977	Valine--pyruvate aminotransferase
HJX18_RS22775	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HJX18_RS22780	COG1414	Transcriptional regulator
HJX18_RS22785	COG3276	selenocysteine insertion sequence binding
HJX18_RS22795	COG0625	glutathione transferase activity
HJX18_RS22810	COG3722	fumarate hydratase activity
HJX18_RS22830	COG2186	Transcriptional regulator
HJX18_RS22840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HJX18_RS22865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HJX18_RS22870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HJX18_RS22880	COG4942	peptidase
HJX18_RS22885	COG2861	carbohydrate metabolic process
HJX18_RS22890	COG0463	Glycosyl transferase, family 2
HJX18_RS22900	COG0156	8-amino-7-oxononanoate synthase activity
HJX18_RS22915	COG0859	PFAM glycosyl transferase family 9
HJX18_RS22920	COG0438	transferase activity, transferring glycosyl groups
HJX18_RS22925	COG3307	-O-antigen
HJX18_RS22930	COG1216	Glycosyl transferase, family 2
HJX18_RS22930	COG1442	glycosyl transferase family 8
HJX18_RS22940	COG0859	PFAM glycosyl transferase family 9
HJX18_RS22950	COG0438	transferase activity, transferring glycosyl groups
HJX18_RS22955	COG1216	Glycosyl transferase, family 2
HJX18_RS22960	COG1519	Transferase
HJX18_RS22995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HJX18_RS23020	COG0842	Transport permease protein
HJX18_RS23025	COG1131	(ABC) transporter
HJX18_RS23050	COG1561	YicC-like family, N-terminal region
HJX18_RS23060	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HJX18_RS23065	COG2169	Transcriptional regulator
HJX18_RS23065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HJX18_RS23075	COG2860	membrane
HJX18_RS23095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HJX18_RS23100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HJX18_RS23105	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HJX18_RS23110	COG1494	fructose-1,6-bisphosphatase
HJX18_RS23120	COG3152	Membrane
HJX18_RS23145	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HJX18_RS23165	COG0786	glutamate:sodium symporter activity
HJX18_RS23170	COG2233	PERMEase
HJX18_RS23175	COG2982	Protein involved in outer membrane biogenesis
HJX18_RS23180	COG1263	PTS System
HJX18_RS23180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJX18_RS23185	COG1486	melibiose metabolic process
HJX18_RS23195	COG1501	Belongs to the glycosyl hydrolase 31 family
HJX18_RS23200	COG2211	Major facilitator Superfamily
HJX18_RS23230	COG1064	alcohol dehydrogenase
HJX18_RS23240	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HJX18_RS23255	COG1464	Belongs to the NlpA lipoprotein family
HJX18_RS23280	COG0583	DNA-binding transcription factor activity
HJX18_RS23315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HJX18_RS23325	COG2814	Major facilitator Superfamily
HJX18_RS23335	COG1263	PTS System
HJX18_RS23335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJX18_RS23340	COG0697	spore germination
HJX18_RS23355	COG2828	Protein conserved in bacteria
HJX18_RS23360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HJX18_RS23365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HJX18_RS23370	COG0583	DNA-binding transcription factor activity
HJX18_RS23375	COG3384	dioxygenase
HJX18_RS23385	COG1609	Transcriptional regulator
HJX18_RS23395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJX18_RS23395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJX18_RS23400	COG1447	Phosphotransferase system cellobiose-specific component IIA
HJX18_RS23405	COG4580	involved in the transport of maltose and maltodextrins
HJX18_RS23430	COG2188	Transcriptional regulator
HJX18_RS23470	COG2271	Major facilitator Superfamily
HJX18_RS23480	COG2197	response regulator
HJX18_RS23485	COG0440	acetolactate synthase activity
HJX18_RS23490	COG0028	Belongs to the TPP enzyme family
HJX18_RS23520	COG2814	Major facilitator Superfamily
HJX18_RS23525	COG0583	DNA-binding transcription factor activity
HJX18_RS23535	COG2610	gluconate transmembrane transporter activity
HJX18_RS23555	COG2149	membrane
HJX18_RS23570	COG2188	Transcriptional regulator
HJX18_RS23595	COG5645	(Lipo)protein
HJX18_RS23600	COG0823	Involved in the tonB-independent uptake of proteins
HJX18_RS23605	COG2271	Major facilitator Superfamily
HJX18_RS23615	COG0800	Aldolase
HJX18_RS23620	COG3734	2-keto-3-deoxy-galactonokinase
HJX18_RS23625	COG2186	Transcriptional regulator
HJX18_RS23640	COG0561	phosphatase activity
HJX18_RS23645	COG0187	DNA topoisomerase II activity
HJX18_RS23675	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HJX18_RS23705	COG2091	lysine biosynthetic process via aminoadipic acid
HJX18_RS23710	COG0431	NADPH-dependent FMN reductase
HJX18_RS23715	COG2252	PERMEase
HJX18_RS23725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HJX18_RS23730	COG0363	glucosamine-6-phosphate deaminase activity
HJX18_RS23735	COG2382	esterase
HJX18_RS23750	COG0704	Plays a role in the regulation of phosphate uptake
HJX18_RS23755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HJX18_RS23760	COG0581	inorganic phosphate transmembrane transporter activity
HJX18_RS23765	COG0573	inorganic phosphate transmembrane transporter activity
HJX18_RS23770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HJX18_RS23775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HJX18_RS23840	COG3312	ion transport
HJX18_RS23855	COG0716	FMN binding
HJX18_RS23860	COG1522	sequence-specific DNA binding
HJX18_RS23890	COG1129	ABC transporter
HJX18_RS23895	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS23905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJX18_RS23910	COG1609	Transcriptional regulator
HJX18_RS23915	COG0477	Major facilitator Superfamily
HJX18_RS23920	COG2186	Transcriptional regulator
HJX18_RS23945	COG1763	Mo-molybdopterin cofactor biosynthetic process
HJX18_RS23955	COG3084	Protein conserved in bacteria
HJX18_RS23960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HJX18_RS23970	COG0204	Acyl-transferase
HJX18_RS23990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HJX18_RS24005	COG3852	Histidine kinase
HJX18_RS24020	COG1011	Hydrolase
HJX18_RS24035	COG0456	acetyltransferase
HJX18_RS24045	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HJX18_RS24060	COG2864	formate dehydrogenase
HJX18_RS24065	COG0437	4 iron, 4 sulfur cluster binding
HJX18_RS24085	COG0205	6-phosphofructokinase activity
HJX18_RS24145	COG2211	Major facilitator Superfamily
HJX18_RS24155	COG1454	alcohol dehydrogenase
HJX18_RS24160	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS24165	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS24170	COG1129	ABC transporter
HJX18_RS24210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HJX18_RS24215	COG2258	MOSC domain
HJX18_RS24220	COG2205	protein histidine kinase activity
HJX18_RS24225	COG0745	RESPONSE REGULATOR receiver
HJX18_RS24230	COG3678	ATP-independent chaperone mediated protein folding
HJX18_RS24250	COG1575	Belongs to the MenA family. Type 1 subfamily
HJX18_RS24265	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HJX18_RS24270	COG1609	Transcriptional regulator
HJX18_RS24275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HJX18_RS24290	COG0626	cystathionine gamma-synthase activity
HJX18_RS24295	COG0527	aspartate kinase activity
HJX18_RS24295	COG0460	homoserine dehydrogenase
HJX18_RS24305	COG0737	Belongs to the 5'-nucleotidase family
HJX18_RS24315	COG0583	DNA-binding transcription factor activity
HJX18_RS24325	COG0697	spore germination
HJX18_RS24330	COG0371	Dehydrogenase
HJX18_RS24340	COG2207	Transcriptional regulator
HJX18_RS24345	COG3443	Belongs to the bacterial solute-binding protein 9 family
HJX18_RS24360	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HJX18_RS24375	COG0583	DNA-binding transcription factor activity
HJX18_RS24450	COG3085	chromosome segregation
HJX18_RS24470	COG3978	acetolactate synthase activity
HJX18_RS24485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HJX18_RS24490	COG0583	DNA-binding transcription factor activity
HJX18_RS24500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HJX18_RS24505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HJX18_RS24515	COG1811	Na channel or pump
HJX18_RS24540	COG3118	belongs to the thioredoxin family
HJX18_RS24545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HJX18_RS24550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HJX18_RS24560	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HJX18_RS24565	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HJX18_RS24570	COG1088	dTDP-glucose 4,6-dehydratase activity
HJX18_RS24575	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HJX18_RS24580	COG0456	acetyltransferase
HJX18_RS24585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HJX18_RS24590	COG2244	polysaccharide biosynthetic process
HJX18_RS24640	COG3071	HemY protein
HJX18_RS24645	COG2959	enzyme of heme biosynthesis
HJX18_RS24660	COG3072	Adenylate cyclase
HJX18_RS24690	COG1011	Hydrolase
HJX18_RS24695	COG0210	DNA helicase
HJX18_RS24725	COG1280	lysine exporter protein (LysE YggA)
HJX18_RS24735	COG1280	lysine exporter protein (LysE YggA)
HJX18_RS24740	COG2267	carboxylic ester hydrolase activity
HJX18_RS24745	COG0561	phosphatase activity
HJX18_RS24750	COG0697	spore germination
HJX18_RS24755	COG0583	DNA-binding transcription factor activity
HJX18_RS24785	COG3165	ubiquinone biosynthetic process from chorismate
HJX18_RS24805	COG0805	protein transport
HJX18_RS24850	COG1739	Uncharacterized protein family UPF0029
HJX18_RS24860	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HJX18_RS24890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HJX18_RS24935	COG0250	Participates in transcription elongation, termination and antitermination
HJX18_RS24970	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HJX18_RS24975	COG1447	Phosphotransferase system cellobiose-specific component IIA
HJX18_RS24985	COG3706	GGDEF domain
HJX18_RS25000	COG2104	thiamine diphosphate biosynthetic process
HJX18_RS25005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HJX18_RS25020	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HJX18_RS25055	COG3678	ATP-independent chaperone mediated protein folding
HJX18_RS25060	COG4191	Histidine kinase
HJX18_RS25070	COG0151	Belongs to the GarS family
HJX18_RS25100	COG0456	acetyltransferase
HJX18_RS25110	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HJX18_RS25140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HJX18_RS25195	COG0527	aspartate kinase activity
HJX18_RS25205	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HJX18_RS25215	COG0251	oxidation-reduction process
HJX18_RS25285	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HJX18_RS25295	COG0534	Mate efflux family protein
HJX18_RS25305	COG3237	CsbD-like
HJX18_RS25310	COG0735	belongs to the Fur family
HJX18_RS25320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HJX18_RS25335	COG0305	Participates in initiation and elongation during chromosome replication
HJX18_RS25340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HJX18_RS25355	COG0432	Pfam Uncharacterised protein family UPF0047
HJX18_RS25360	COG2315	Protein conserved in bacteria
HJX18_RS25375	COG0741	lytic transglycosylase activity
HJX18_RS25385	COG4771	TonB-dependent receptor
HJX18_RS25410	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HJX18_RS25420	COG0483	inositol monophosphate 1-phosphatase activity
HJX18_RS25425	COG1609	Transcriptional regulator
HJX18_RS25430	COG1234	tRNA 3'-trailer cleavage
HJX18_RS25460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HJX18_RS25470	COG0789	Transcriptional regulator
HJX18_RS25475	COG0625	glutathione transferase activity
HJX18_RS25480	COG2252	PERMEase
HJX18_RS25485	COG0025	NhaP-type Na H and K H
HJX18_RS25490	COG0583	DNA-binding transcription factor activity
HJX18_RS25495	COG1380	Effector of murein hydrolase LrgA
HJX18_RS25500	COG1346	cytolysis
HJX18_RS25510	COG3539	Fimbrial protein
HJX18_RS25540	COG3162	membrane
HJX18_RS25545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HJX18_RS25555	COG1301	dicarboxylic acid transport
HJX18_RS25560	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HJX18_RS25595	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS25600	COG1129	ABC transporter
HJX18_RS25605	COG0784	Response regulator, receiver
HJX18_RS25605	COG4191	Histidine kinase
HJX18_RS25615	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HJX18_RS25625	COG3454	Phosphonate metabolism
HJX18_RS25630	COG4778	phosphonate C-P lyase system protein PhnL
HJX18_RS25635	COG4107	phosphonate C-P lyase system protein PhnK
HJX18_RS25640	COG3627	carbon phosphorus lyase activity
HJX18_RS25645	COG3626	phosphonate metabolism
HJX18_RS25650	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HJX18_RS25655	COG3624	Phosphonate C-P lyase system protein PhnG
HJX18_RS25660	COG2188	Transcriptional regulator
HJX18_RS25665	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HJX18_RS25670	COG2824	Alkylphosphonate utilization operon protein PhnA
HJX18_RS25680	COG2169	Transcriptional regulator
HJX18_RS25685	COG1486	melibiose metabolic process
HJX18_RS25725	COG0861	Integral membrane protein TerC family
HJX18_RS25745	COG1215	transferase activity, transferring glycosyl groups
HJX18_RS25750	COG1649	PFAM Uncharacterised BCR, COG1649
HJX18_RS25750	COG0726	polysaccharide deacetylase
HJX18_RS25755	COG0457	Tetratricopeptide repeat
HJX18_RS25795	COG1309	transcriptional regulator
HJX18_RS25810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HJX18_RS25815	COG1027	Aspartate ammonia-lyase
HJX18_RS25820	COG3030	protein affecting phage T7 exclusion by the F plasmid
HJX18_RS25825	COG0531	amino acid
HJX18_RS25895	COG1509	lysine 2,3-aminomutase activity
HJX18_RS25910	COG5510	response to toxic substance
HJX18_RS25915	COG2076	Multidrug Resistance protein
HJX18_RS25935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HJX18_RS25940	COG1053	succinate dehydrogenase
HJX18_RS25955	COG3264	Mechanosensitive ion channel
HJX18_RS25955	COG1511	domain protein
HJX18_RS25975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HJX18_RS25990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HJX18_RS25995	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HJX18_RS25995	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HJX18_RS26000	COG0802	atpase or kinase
HJX18_RS26005	COG0860	N-Acetylmuramoyl-L-alanine amidase
HJX18_RS26030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HJX18_RS26035	COG0330	HflC and HflK could
HJX18_RS26040	COG0330	HflC and HflK could
HJX18_RS26050	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HJX18_RS26065	COG0557	exoribonuclease II activity
HJX18_RS26070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HJX18_RS26075	COG1960	acyl-CoA dehydrogenase activity
HJX18_RS26085	COG3650	response to hydrogen peroxide
HJX18_RS26090	COG1073	alpha beta
HJX18_RS26150	COG2965	DNA replication, synthesis of RNA primer
HJX18_RS26155	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HJX18_RS26165	COG3061	Opacity-associated protein A
HJX18_RS26170	COG0545	Peptidyl-prolyl cis-trans isomerase
HJX18_RS26175	COG1113	amino acid transport
HJX18_RS26185	COG0697	spore germination
HJX18_RS26195	COG0702	epimerase
HJX18_RS26200	COG1733	regulation of RNA biosynthetic process
HJX18_RS26215	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HJX18_RS26240	COG1253	flavin adenine dinucleotide binding
HJX18_RS26250	COG0729	surface antigen
HJX18_RS26255	COG2911	Protein conserved in bacteria
HJX18_RS26260	COG2105	PFAM AIG2 family protein
HJX18_RS26280	COG1879	ABC-type sugar transport system periplasmic component
HJX18_RS26285	COG1129	ABC transporter
HJX18_RS26290	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS26295	COG1172	Belongs to the binding-protein-dependent transport system permease family
HJX18_RS26305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HJX18_RS26330	COG0312	modulator of DNA gyrase
HJX18_RS26365	COG3964	amidohydrolase
HJX18_RS26380	COG2706	6-phosphogluconolactonase activity
HJX18_RS26385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HJX18_RS26385	COG3711	transcriptional antiterminator
HJX18_RS26390	COG3077	Addiction module antitoxin, RelB DinJ family
HJX18_RS26400	COG0602	queuosine metabolic process
HJX18_RS26425	COG1486	melibiose metabolic process
HJX18_RS26430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HJX18_RS26435	COG0366	Alpha amylase catalytic
HJX18_RS26440	COG1263	PTS System
HJX18_RS26440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HJX18_RS26475	COG2731	YhcH YjgK YiaL family protein
HJX18_RS26485	COG2222	sugar isomerase
HJX18_RS26490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJX18_RS26495	COG1228	amidohydrolase
HJX18_RS26500	COG1288	antiporter activity
HJX18_RS26505	COG2188	Transcriptional regulator
HJX18_RS26530	COG0525	valine-tRNA ligase activity
HJX18_RS26535	COG2927	DNA polymerase III (CHI subunit)
HJX18_RS26545	COG0795	lipopolysaccharide-transporting ATPase activity
HJX18_RS26550	COG0795	lipopolysaccharide-transporting ATPase activity
HJX18_RS26555	COG0433	COG0433 Predicted ATPase
HJX18_RS26570	COG3718	enzyme involved in inositol metabolism
HJX18_RS26635	COG1192	Involved in chromosome partitioning
HJX18_RS26945	COG2805	Type II/IV secretion system protein
HJX18_RS26990	COG0741	lytic transglycosylase activity
HJX18_RS27005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HJX18_RS27080	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system