locus-tag	class	description
A8C02_RS00130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A8C02_RS00150	COG2205	protein histidine kinase activity
A8C02_RS00150	COG3437	response regulator, receiver
A8C02_RS00150	COG3850	Histidine kinase
A8C02_RS00150	COG4999	Histidine kinase
A8C02_RS00420	COG3260	NADH ubiquinone oxidoreductase 20
A8C02_RS00435	COG2723	6-phospho-beta-galactosidase activity
A8C02_RS00455	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A8C02_RS00655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A8C02_RS00670	COG2814	Major facilitator Superfamily
A8C02_RS00685	COG1566	PFAM secretion protein HlyD family protein
A8C02_RS00755	COG2204	response regulator
A8C02_RS00760	COG3284	Transcriptional regulator
A8C02_RS01240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C02_RS01240	COG0045	succinate-CoA ligase (ADP-forming) activity
A8C02_RS01240	COG1042	CoA-binding domain protein
A8C02_RS01245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C02_RS01245	COG1042	CoA-binding domain protein
A8C02_RS01245	COG0045	succinate-CoA ligase (ADP-forming) activity
A8C02_RS01285	COG0513	Belongs to the DEAD box helicase family
A8C02_RS01325	COG0681	Belongs to the peptidase S26 family
A8C02_RS01530	COG2373	Large extracellular alpha-helical protein
A8C02_RS01550	COG4953	penicillin-binding protein 1C
A8C02_RS01640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A8C02_RS01645	COG0163	prenyltransferase activity
A8C02_RS01670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A8C02_RS01675	COG4942	peptidase
A8C02_RS01675	COG1388	LysM domain
A8C02_RS01735	COG2234	aminopeptidase activity
A8C02_RS01760	COG0720	synthase
A8C02_RS01765	COG0602	queuosine metabolic process
A8C02_RS01785	COG3956	TIGRFAM MazG family protein
A8C02_RS01790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A8C02_RS01800	COG4999	Histidine kinase
A8C02_RS01800	COG2205	protein histidine kinase activity
A8C02_RS01800	COG3850	Histidine kinase
A8C02_RS01800	COG3437	response regulator, receiver
A8C02_RS01895	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A8C02_RS01900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C02_RS01905	COG4558	Periplasmic binding protein
A8C02_RS01910	COG3720	iron ion transport
A8C02_RS01930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8C02_RS01935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8C02_RS01940	COG1121	(ABC) transporter
A8C02_RS01955	COG0309	Hydrogenase expression formation protein (HypE)
A8C02_RS01960	COG0409	Hydrogenase expression formation protein
A8C02_RS01965	COG0298	carbon dioxide binding
A8C02_RS01970	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A8C02_RS01985	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8C02_RS01990	COG0651	ATP synthesis coupled electron transport
A8C02_RS01995	COG0650	Formate hydrogenlyase subunit 4
A8C02_RS02000	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A8C02_RS02000	COG3261	NADH dehydrogenase
A8C02_RS02005	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8C02_RS02010	COG3260	NADH ubiquinone oxidoreductase 20
A8C02_RS02020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A8C02_RS02030	COG2723	6-phospho-beta-galactosidase activity
A8C02_RS02035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C02_RS02035	COG1263	PTS System
A8C02_RS02045	COG1609	Transcriptional regulator
A8C02_RS02050	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8C02_RS02055	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A8C02_RS02060	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A8C02_RS02070	COG2814	Major facilitator Superfamily
A8C02_RS02080	COG1414	Transcriptional regulator
A8C02_RS02085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A8C02_RS02090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8C02_RS02115	COG1349	DNA-binding transcription factor activity
A8C02_RS02120	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C02_RS02125	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS02135	COG3732	PTS system glucitol sorbitol-specific
A8C02_RS02140	COG3730	PTS system glucitol sorbitol-specific
A8C02_RS02145	COG2951	lytic endotransglycosylase activity
A8C02_RS02155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8C02_RS02160	COG0803	Belongs to the bacterial solute-binding protein 9 family
A8C02_RS02165	COG1546	Belongs to the CinA family
A8C02_RS02185	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A8C02_RS02220	COG2823	Periplasmic or secreted lipoprotein
A8C02_RS02225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8C02_RS02230	COG1238	metal cluster binding
A8C02_RS02250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A8C02_RS02255	COG2814	Major facilitator Superfamily
A8C02_RS02260	COG1566	PFAM secretion protein HlyD family protein
A8C02_RS02270	COG1846	Transcriptional regulator
A8C02_RS02285	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A8C02_RS02295	COG4176	ABC-type proline glycine betaine transport system permease component
A8C02_RS02310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A8C02_RS02320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A8C02_RS02325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8C02_RS02335	COG4575	ribosome binding
A8C02_RS02370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8C02_RS02375	COG0640	Transcriptional regulator
A8C02_RS02385	COG0583	DNA-binding transcription factor activity
A8C02_RS02390	COG3284	Transcriptional regulator
A8C02_RS02400	COG3539	Fimbrial protein
A8C02_RS02405	COG3121	Chaperone
A8C02_RS02420	COG3121	Chaperone
A8C02_RS02440	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS02450	COG0235	Class ii aldolase
A8C02_RS02460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C02_RS02490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8C02_RS02520	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A8C02_RS02540	COG0431	NADPH-dependent FMN reductase
A8C02_RS02555	COG2271	Major facilitator Superfamily
A8C02_RS02565	COG0477	Major facilitator Superfamily
A8C02_RS02570	COG3622	Belongs to the hyi family
A8C02_RS02595	COG0582	viral genome integration into host DNA
A8C02_RS02610	COG2867	negative regulation of translational initiation
A8C02_RS02630	COG0497	DNA recombination
A8C02_RS02645	COG4536	flavin adenine dinucleotide binding
A8C02_RS02650	COG4137	Cytochrome C assembly protein
A8C02_RS02655	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A8C02_RS02695	COG2885	chlorophyll binding
A8C02_RS02700	COG2199	diguanylate cyclase activity
A8C02_RS02710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A8C02_RS02715	COG0287	Prephenate dehydrogenase
A8C02_RS02715	COG1605	Chorismate mutase
A8C02_RS02725	COG1605	Chorismate mutase
A8C02_RS02725	COG0077	Prephenate dehydratase
A8C02_RS02730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A8C02_RS02735	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8C02_RS02750	COG0542	response to heat
A8C02_RS02780	COG0477	Major facilitator Superfamily
A8C02_RS02785	COG5544	Lipoprotein
A8C02_RS02790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8C02_RS02800	COG3148	PFAM DTW domain containing protein
A8C02_RS02805	COG3118	belongs to the thioredoxin family
A8C02_RS02810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8C02_RS02825	COG0513	Belongs to the DEAD box helicase family
A8C02_RS02835	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A8C02_RS02845	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
A8C02_RS02850	COG3026	antisigma factor binding
A8C02_RS02855	COG3086	response to oxidative stress
A8C02_RS02865	COG0681	Belongs to the peptidase S26 family
A8C02_RS02890	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A8C02_RS02900	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8C02_RS02905	COG1737	Transcriptional regulator
A8C02_RS02910	COG0560	Phosphoserine phosphatase
A8C02_RS02925	COG0047	phosphoribosylformylglycinamidine synthase activity
A8C02_RS02925	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A8C02_RS02930	COG2205	protein histidine kinase activity
A8C02_RS02935	COG3170	Tfp pilus assembly protein FimV
A8C02_RS02940	COG2204	response regulator
A8C02_RS02945	COG0347	Belongs to the P(II) protein family
A8C02_RS02950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8C02_RS02950	COG1017	nitric oxide dioxygenase activity
A8C02_RS02960	COG2259	Doxx family
A8C02_RS02985	COG4638	Rieske (2fe-2S)
A8C02_RS02990	COG0583	DNA-binding transcription factor activity
A8C02_RS02995	COG2814	Major facilitator Superfamily
A8C02_RS03000	COG3711	transcriptional antiterminator
A8C02_RS03005	COG3683	transport system, periplasmic component
A8C02_RS03010	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
A8C02_RS03035	COG0822	iron-sulfur transferase activity
A8C02_RS03055	COG0633	Ferredoxin
A8C02_RS03060	COG2975	iron-sulfur cluster assembly
A8C02_RS03085	COG2897	thiosulfate sulfurtransferase activity
A8C02_RS03090	COG2373	Large extracellular alpha-helical protein
A8C02_RS03095	COG4953	penicillin-binding protein 1C
A8C02_RS03125	COG2976	Protein conserved in bacteria
A8C02_RS03145	COG1645	bacterial-type flagellum-dependent swarming motility
A8C02_RS03155	COG0517	IMP dehydrogenase activity
A8C02_RS03155	COG0516	GMP reductase activity
A8C02_RS03180	COG2200	EAL domain
A8C02_RS03195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A8C02_RS03210	COG2723	6-phospho-beta-galactosidase activity
A8C02_RS03220	COG2233	PERMEase
A8C02_RS03235	COG1393	Belongs to the ArsC family
A8C02_RS03240	COG4783	chaperone-mediated protein folding
A8C02_RS03250	COG0628	permease
A8C02_RS03255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A8C02_RS03260	COG2716	regulation of RNA biosynthetic process
A8C02_RS03270	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
A8C02_RS03280	COG2321	neutral zinc metallopeptidase
A8C02_RS03290	COG0400	carboxylic ester hydrolase activity
A8C02_RS03305	COG1393	Belongs to the ArsC family
A8C02_RS03310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8C02_RS03315	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8C02_RS03315	COG0493	'glutamate synthase
A8C02_RS03325	COG5342	invasion associated locus B
A8C02_RS03330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A8C02_RS03335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A8C02_RS03350	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8C02_RS03370	COG2837	iron assimilation
A8C02_RS03385	COG4150	thiosulfate binding
A8C02_RS03390	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A8C02_RS03395	COG4208	sulfate ABC transporter
A8C02_RS03400	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A8C02_RS03410	COG4319	ketosteroid isomerase
A8C02_RS03450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A8C02_RS03475	COG3530	Putative quorum-sensing-regulated virulence factor
A8C02_RS03480	COG0385	Bile acid
A8C02_RS03485	COG0583	DNA-binding transcription factor activity
A8C02_RS03525	COG3415	Transposase
A8C02_RS03530	COG3415	Transposase
A8C02_RS03545	COG2200	EAL domain
A8C02_RS03545	COG2199	diguanylate cyclase activity
A8C02_RS03550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C02_RS03565	COG0667	Aldo Keto reductase
A8C02_RS03570	COG3961	Belongs to the TPP enzyme family
A8C02_RS03585	COG3279	Response regulator of the LytR AlgR family
A8C02_RS03590	COG3275	phosphorelay sensor kinase activity
A8C02_RS03600	COG0436	Aminotransferase
A8C02_RS03605	COG2807	transmembrane transport
A8C02_RS03610	COG0590	tRNA wobble adenosine to inosine editing
A8C02_RS03615	COG0583	DNA-binding transcription factor activity
A8C02_RS03650	COG1360	Flagellar Motor Protein
A8C02_RS03715	COG4372	Transposase
A8C02_RS03720	COG3436	PFAM IS66 Orf2 family protein
A8C02_RS03785	COG2116	formate transmembrane transporter activity
A8C02_RS03790	COG2853	Lipoprotein
A8C02_RS03800	COG3691	Protein conserved in bacteria
A8C02_RS03815	COG2062	phosphohistidine phosphatase, SixA
A8C02_RS03840	COG0730	response to heat
A8C02_RS03845	COG3101	peptidyl-lysine hydroxylation
A8C02_RS03860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A8C02_RS03880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A8C02_RS03890	COG0586	Pfam SNARE associated Golgi protein
A8C02_RS03900	COG0285	dihydrofolate synthase activity
A8C02_RS03905	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
A8C02_RS03910	COG1286	toxin biosynthetic process
A8C02_RS03915	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A8C02_RS03920	COG0163	prenyltransferase activity
A8C02_RS03945	COG4160	amino acid transport
A8C02_RS03950	COG4598	ABC transporter
A8C02_RS03965	COG1090	epimerase
A8C02_RS03970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A8C02_RS03975	COG0625	glutathione transferase activity
A8C02_RS03980	COG0625	glutathione transferase activity
A8C02_RS03985	COG0622	Phosphoesterase
A8C02_RS03990	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
A8C02_RS03995	COG0857	belongs to the CobB CobQ family
A8C02_RS03995	COG0280	phosphate acetyltransferase
A8C02_RS04015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8C02_RS04020	COG0490	domain, Protein
A8C02_RS04020	COG0471	metal ion transport
A8C02_RS04030	COG0436	Aminotransferase
A8C02_RS04035	COG0583	DNA-binding transcription factor activity
A8C02_RS04085	COG0839	Belongs to the complex I subunit 6 family
A8C02_RS04095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A8C02_RS04100	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8C02_RS04115	COG2153	protein acetylation
A8C02_RS04120	COG1169	isochorismate synthase
A8C02_RS04170	COG0642	Histidine kinase
A8C02_RS04180	COG5464	transposase or invertase
A8C02_RS04195	COG1414	Transcriptional regulator
A8C02_RS04205	COG2271	Major facilitator Superfamily
A8C02_RS04215	COG0247	lactate metabolic process
A8C02_RS04225	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A8C02_RS04230	COG2271	Major facilitator Superfamily
A8C02_RS04235	COG0584	glycerophosphoryl diester phosphodiesterase
A8C02_RS04240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8C02_RS04265	COG0784	Response regulator, receiver
A8C02_RS04265	COG2205	protein histidine kinase activity
A8C02_RS04275	COG0642	Histidine kinase
A8C02_RS04275	COG2198	Histidine kinase
A8C02_RS04290	COG2169	Transcriptional regulator
A8C02_RS04290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A8C02_RS04295	COG3145	DNA-N1-methyladenine dioxygenase activity
A8C02_RS04300	COG4615	Cyclic peptide transporter
A8C02_RS04305	COG2239	Acts as a magnesium transporter
A8C02_RS04310	COG0659	secondary active sulfate transmembrane transporter activity
A8C02_RS04325	COG0628	permease
A8C02_RS04350	COG1349	DNA-binding transcription factor activity
A8C02_RS04355	COG0494	nUDIX hydrolase
A8C02_RS04375	COG1061	Type III restriction enzyme res subunit
A8C02_RS04380	COG1187	pseudouridine synthase activity
A8C02_RS04385	COG2814	Major facilitator Superfamily
A8C02_RS04395	COG4172	Belongs to the ABC transporter superfamily
A8C02_RS04400	COG4239	(ABC) transporter, permease
A8C02_RS04405	COG4174	ABC transporter (Permease)
A8C02_RS04410	COG4166	transmembrane transport
A8C02_RS04420	COG0791	NLP P60 protein
A8C02_RS04425	COG0671	phosphoesterase, PA-phosphatase related
A8C02_RS04430	COG0523	cobalamin synthesis protein
A8C02_RS04435	COG0246	Mannitol dehydrogenase
A8C02_RS04440	COG1312	Catalyzes the dehydration of D-mannonate
A8C02_RS04465	COG1566	PFAM secretion protein HlyD family protein
A8C02_RS04480	COG1105	Belongs to the carbohydrate kinase PfkB family
A8C02_RS04485	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A8C02_RS04485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C02_RS04485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A8C02_RS04495	COG2855	membrane
A8C02_RS04505	COG0583	DNA-binding transcription factor activity
A8C02_RS04510	COG0833	amino acid
A8C02_RS04515	COG4771	TonB-dependent receptor
A8C02_RS04530	COG2311	Membrane
A8C02_RS04545	COG1129	ABC transporter
A8C02_RS04555	COG2949	membrane
A8C02_RS04565	COG1346	cytolysis
A8C02_RS04575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A8C02_RS04580	COG3659	wide pore channel activity
A8C02_RS04595	COG2723	6-phospho-beta-galactosidase activity
A8C02_RS04605	COG1538	Outer membrane efflux protein
A8C02_RS04610	COG0586	Pfam SNARE associated Golgi protein
A8C02_RS04620	COG1686	Belongs to the peptidase S11 family
A8C02_RS04630	COG0277	FAD linked oxidase domain protein
A8C02_RS04635	COG1472	Belongs to the glycosyl hydrolase 3 family
A8C02_RS04640	COG1732	Glycine betaine
A8C02_RS04645	COG1174	glycine betaine transport
A8C02_RS04650	COG1125	glycine betaine transport
A8C02_RS04655	COG1174	glycine betaine transport
A8C02_RS04665	COG3275	phosphorelay sensor kinase activity
A8C02_RS04675	COG4807	Protein conserved in bacteria
A8C02_RS04695	COG5455	response to cobalt ion
A8C02_RS04700	COG0583	DNA-binding transcription factor activity
A8C02_RS04705	COG2252	PERMEase
A8C02_RS04715	COG0583	DNA-binding transcription factor activity
A8C02_RS04735	COG0351	phosphomethylpyrimidine kinase
A8C02_RS04740	COG1830	Aldolase
A8C02_RS04775	COG1070	Carbohydrate kinase
A8C02_RS04785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8C02_RS04790	COG4948	Mandelate Racemase Muconate Lactonizing
A8C02_RS04795	COG0747	negative chemotaxis
A8C02_RS04800	COG0601	transmembrane transport
A8C02_RS04805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C02_RS04810	COG0444	Belongs to the ABC transporter superfamily
A8C02_RS04815	COG4608	Belongs to the ABC transporter superfamily
A8C02_RS04825	COG0826	peptidase U32
A8C02_RS04830	COG0745	RESPONSE REGULATOR receiver
A8C02_RS04835	COG2205	protein histidine kinase activity
A8C02_RS04860	COG1301	dicarboxylic acid transport
A8C02_RS04890	COG3039	Transposase
A8C02_RS04900	COG5002	protein histidine kinase activity
A8C02_RS04905	COG0443	Heat shock 70 kDa protein
A8C02_RS04910	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A8C02_RS04925	COG2982	Protein involved in outer membrane biogenesis
A8C02_RS04930	COG1253	flavin adenine dinucleotide binding
A8C02_RS04965	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A8C02_RS04970	COG2244	polysaccharide biosynthetic process
A8C02_RS04975	COG0438	transferase activity, transferring glycosyl groups
A8C02_RS04995	COG0438	transferase activity, transferring glycosyl groups
A8C02_RS05065	COG2963	transposase activity
A8C02_RS05095	COG0438	transferase activity, transferring glycosyl groups
A8C02_RS05100	COG1215	transferase activity, transferring glycosyl groups
A8C02_RS05115	COG0463	Glycosyl transferase, family 2
A8C02_RS05140	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A8C02_RS05165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8C02_RS05170	COG0583	DNA-binding transcription factor activity
A8C02_RS05175	COG0531	amino acid
A8C02_RS05195	COG3604	Transcriptional regulator
A8C02_RS05200	COG2205	protein histidine kinase activity
A8C02_RS05285	COG0640	Transcriptional regulator
A8C02_RS05290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A8C02_RS05295	COG2925	Exonuclease
A8C02_RS05310	COG1289	transmembrane transporter activity
A8C02_RS05330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A8C02_RS05340	COG1942	4-Oxalocrotonate Tautomerase
A8C02_RS05345	COG0583	DNA-binding transcription factor activity
A8C02_RS05350	COG0095	Lipoate-protein ligase
A8C02_RS05355	COG0477	Major facilitator Superfamily
A8C02_RS05365	COG5001	Diguanylate cyclase
A8C02_RS05365	COG3300	MHYT domain
A8C02_RS05375	COG3615	Tellurite resistance protein tehB
A8C02_RS05420	COG2801	Transposase and inactivated derivatives
A8C02_RS05425	COG2963	transposase activity
A8C02_RS05435	COG1737	Transcriptional regulator
A8C02_RS05465	COG0534	Mate efflux family protein
A8C02_RS05475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A8C02_RS05495	COG0604	alcohol dehydrogenase
A8C02_RS05500	COG1309	transcriptional regulator
A8C02_RS05505	COG0025	NhaP-type Na H and K H
A8C02_RS05560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A8C02_RS05570	COG1418	mRNA catabolic process
A8C02_RS05575	COG0270	DNA (cytosine-5-)-methyltransferase activity
A8C02_RS05580	COG3727	T/G mismatch-specific endonuclease activity
A8C02_RS05585	COG0697	spore germination
A8C02_RS05590	COG2354	Protein conserved in bacteria
A8C02_RS05620	COG0366	Alpha amylase catalytic
A8C02_RS05625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C02_RS05635	COG0765	amino acid transport
A8C02_RS05640	COG1126	abc transporter atp-binding protein
A8C02_RS05645	COG2197	response regulator
A8C02_RS05655	COG2197	response regulator
A8C02_RS05685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A8C02_RS05690	COG3012	SEC-C Motif Domain Protein
A8C02_RS05690	COG3318	Belongs to the UPF0149 family
A8C02_RS05695	COG0814	amino acid
A8C02_RS05705	COG1528	Iron-storage protein
A8C02_RS05720	COG0477	Major facilitator Superfamily
A8C02_RS05730	COG2211	Major facilitator Superfamily
A8C02_RS05740	COG1528	Iron-storage protein
A8C02_RS05745	COG1879	ABC-type sugar transport system periplasmic component
A8C02_RS05755	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS05780	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A8C02_RS05790	COG3102	Protein conserved in bacteria
A8C02_RS05810	COG3788	relative of glutathione S-transferase, MAPEG superfamily
A8C02_RS05815	COG1801	Protein of unknown function DUF72
A8C02_RS05820	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A8C02_RS05825	COG2801	Transposase and inactivated derivatives
A8C02_RS05830	COG2963	transposase activity
A8C02_RS05875	COG1801	Protein of unknown function DUF72
A8C02_RS05880	COG1335	isochorismatase
A8C02_RS05890	COG0494	nUDIX hydrolase
A8C02_RS05915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A8C02_RS05925	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
A8C02_RS05930	COG0739	heme binding
A8C02_RS05935	COG1560	Kdo2-lipid A biosynthetic process
A8C02_RS05945	COG1737	Transcriptional regulator
A8C02_RS05955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A8C02_RS05960	COG0129	dihydroxy-acid dehydratase activity
A8C02_RS05965	COG0800	Aldolase
A8C02_RS05975	COG3141	response to X-ray
A8C02_RS05980	COG2979	Protein of unknown function (DUF533)
A8C02_RS05985	COG1770	oligopeptidase
A8C02_RS05990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8C02_RS06000	COG2372	response to copper ion
A8C02_RS06005	COG1276	copper resistance
A8C02_RS06020	COG2990	Protein conserved in bacteria
A8C02_RS06045	COG3008	intermembrane lipid transfer
A8C02_RS06050	COG2995	paraquat-inducible protein a
A8C02_RS06055	COG1956	GAF domain-containing protein
A8C02_RS06075	COG2814	Major facilitator Superfamily
A8C02_RS06080	COG1414	Transcriptional regulator
A8C02_RS06110	COG0768	penicillin binding
A8C02_RS06115	COG2226	methyltransferase
A8C02_RS06130	COG3716	PTS system mannose fructose sorbose family IID component
A8C02_RS06135	COG3715	PTS system
A8C02_RS06140	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C02_RS06140	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C02_RS06145	COG1253	flavin adenine dinucleotide binding
A8C02_RS06150	COG2200	EAL domain
A8C02_RS06160	COG1760	l-serine dehydratase
A8C02_RS06180	COG0251	oxidation-reduction process
A8C02_RS06185	COG1199	ATP-dependent helicase activity
A8C02_RS06195	COG3065	identical protein binding
A8C02_RS06205	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A8C02_RS06215	COG2894	cell division
A8C02_RS06235	COG0179	Fumarylacetoacetate (FAA) hydrolase
A8C02_RS06265	COG2719	SpoVR family
A8C02_RS06290	COG1619	proteins homologs of microcin C7 resistance protein MccF
A8C02_RS06300	COG4774	siderophore transport
A8C02_RS06310	COG2308	Evidence 4 Homologs of previously reported genes of
A8C02_RS06355	COG0583	DNA-binding transcription factor activity
A8C02_RS06360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A8C02_RS06375	COG1882	Formate acetyltransferase
A8C02_RS06410	COG0583	DNA-binding transcription factor activity
A8C02_RS06440	COG0583	DNA-binding transcription factor activity
A8C02_RS06445	COG0582	viral genome integration into host DNA
A8C02_RS06495	COG1846	Transcriptional regulator
A8C02_RS06555	COG4725	Belongs to the MT-A70-like family
A8C02_RS06575	COG3772	lysozyme
A8C02_RS06605	COG4626	Terminase
A8C02_RS06605	COG1802	Transcriptional regulator
A8C02_RS06615	COG4695	Portal protein
A8C02_RS06715	COG2842	Transposition protein
A8C02_RS06745	COG4382	Mu-like prophage protein Gp16
A8C02_RS06755	COG3039	Transposase
A8C02_RS06785	COG0640	Transcriptional regulator
A8C02_RS06800	COG4373	Mu-like prophage FluMu protein gp28
A8C02_RS06820	COG4397	Mu-like prophage major head subunit gpT
A8C02_RS06850	COG4386	tail sheath protein
A8C02_RS06880	COG4384	Bacteriophage Mu Gp45 protein
A8C02_RS06890	COG3299	homolog of phage Mu protein gp47
A8C02_RS06900	COG5301	cellulose 1,4-beta-cellobiosidase activity
A8C02_RS06905	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A8C02_RS06910	COG5301	cellulose 1,4-beta-cellobiosidase activity
A8C02_RS06935	COG0583	DNA-binding transcription factor activity
A8C02_RS06950	COG3122	Protein conserved in bacteria
A8C02_RS07060	COG0012	GTP binding
A8C02_RS07080	COG0659	secondary active sulfate transmembrane transporter activity
A8C02_RS07110	COG2890	protein-(glutamine-N5) methyltransferase activity
A8C02_RS07130	COG0387	Pfam Sodium calcium exchanger
A8C02_RS07135	COG4572	Cation transport regulator
A8C02_RS07140	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
A8C02_RS07150	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A8C02_RS07155	COG3707	response regulator
A8C02_RS07165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8C02_RS07175	COG1116	anion transmembrane transporter activity
A8C02_RS07180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A8C02_RS07180	COG2146	nitrite reductase [NAD(P)H] activity
A8C02_RS07185	COG0243	molybdopterin cofactor binding
A8C02_RS07190	COG4932	domain protein
A8C02_RS07195	COG2197	response regulator
A8C02_RS07200	COG3850	Histidine kinase
A8C02_RS07205	COG2223	nitrite transmembrane transporter activity
A8C02_RS07215	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A8C02_RS07220	COG1140	nitrate reductase beta subunit
A8C02_RS07225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A8C02_RS07230	COG2181	nitrate reductase activity
A8C02_RS07240	COG1522	sequence-specific DNA binding
A8C02_RS07270	COG0788	formyltetrahydrofolate deformylase activity
A8C02_RS07280	COG1752	Esterase of the alpha-beta hydrolase superfamily
A8C02_RS07285	COG0745	RESPONSE REGULATOR receiver
A8C02_RS07290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A8C02_RS07295	COG2916	Histone family protein nucleoid-structuring protein H-NS
A8C02_RS07305	COG1435	thymidine kinase activity
A8C02_RS07310	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS07310	COG1454	alcohol dehydrogenase
A8C02_RS07320	COG2095	MarC family integral membrane protein
A8C02_RS07330	COG4166	transmembrane transport
A8C02_RS07335	COG0601	transmembrane transport
A8C02_RS07340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C02_RS07345	COG0444	Belongs to the ABC transporter superfamily
A8C02_RS07355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8C02_RS07380	COG2353	YceI-like domain
A8C02_RS07390	COG2350	Protein conserved in bacteria
A8C02_RS07400	COG3001	Fructosamine kinase
A8C02_RS07410	COG1105	Belongs to the carbohydrate kinase PfkB family
A8C02_RS07415	COG3137	Salt-induced outer membrane protein
A8C02_RS07450	COG0072	phenylalanine-tRNA ligase activity
A8C02_RS07450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A8C02_RS07470	COG0583	DNA-binding transcription factor activity
A8C02_RS07490	COG0386	Belongs to the glutathione peroxidase family
A8C02_RS07500	COG0791	NLP P60 protein
A8C02_RS07510	COG4256	Hemin uptake protein
A8C02_RS07515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A8C02_RS07530	COG0574	Belongs to the PEP-utilizing enzyme family
A8C02_RS07530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A8C02_RS07540	COG0628	permease
A8C02_RS07545	COG0247	lactate metabolic process
A8C02_RS07545	COG0277	FAD linked oxidase domain protein
A8C02_RS07550	COG2050	protein possibly involved in aromatic compounds catabolism
A8C02_RS07555	COG2261	transglycosylase associated protein
A8C02_RS07585	COG1120	ATPase activity
A8C02_RS07590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C02_RS07600	COG0583	DNA-binding transcription factor activity
A8C02_RS07625	COG1304	FMN binding
A8C02_RS07640	COG0316	Belongs to the HesB IscA family
A8C02_RS07645	COG0719	Fe-S assembly protein
A8C02_RS07650	COG0396	ATPase activity
A8C02_RS07655	COG0719	Fe-S assembly protein
A8C02_RS07670	COG1376	ErfK ybiS ycfS ynhG family protein
A8C02_RS07700	COG1309	transcriptional regulator
A8C02_RS07705	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A8C02_RS07705	COG1082	Xylose isomerase domain protein TIM barrel
A8C02_RS07710	COG2271	Major facilitator Superfamily
A8C02_RS07715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A8C02_RS07725	COG1120	ATPase activity
A8C02_RS07730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C02_RS07735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8C02_RS07740	COG1414	Transcriptional regulator
A8C02_RS07775	COG2814	Major facilitator Superfamily
A8C02_RS07795	COG0583	DNA-binding transcription factor activity
A8C02_RS07800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C02_RS07820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C02_RS07825	COG1116	anion transmembrane transporter activity
A8C02_RS07830	COG4774	siderophore transport
A8C02_RS07835	COG1120	ATPase activity
A8C02_RS07840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C02_RS07845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C02_RS07870	COG0765	amino acid transport
A8C02_RS07875	COG1126	abc transporter atp-binding protein
A8C02_RS07905	COG1473	amidohydrolase
A8C02_RS07910	COG3383	formate dehydrogenase (NAD+) activity
A8C02_RS07915	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A8C02_RS07930	COG1175	transmembrane transport
A8C02_RS07960	COG4133	protoheme IX ABC transporter activity
A8C02_RS07965	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8C02_RS07970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A8C02_RS07985	COG1138	Cytochrome C-type biogenesis protein
A8C02_RS07990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8C02_RS07995	COG4235	cytochrome complex assembly
A8C02_RS07995	COG3088	subunit of a heme lyase
A8C02_RS08010	COG2801	Transposase and inactivated derivatives
A8C02_RS08015	COG3344	reverse transcriptase
A8C02_RS08020	COG2963	transposase activity
A8C02_RS08050	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS08055	COG2610	gluconate transmembrane transporter activity
A8C02_RS08060	COG1250	3-hydroxyacyl-CoA dehydrogenase
A8C02_RS08070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A8C02_RS08080	COG0583	DNA-binding transcription factor activity
A8C02_RS08100	COG0277	FAD linked oxidase domain protein
A8C02_RS08105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C02_RS08130	COG0402	S-adenosylhomocysteine deaminase activity
A8C02_RS08185	COG4608	Belongs to the ABC transporter superfamily
A8C02_RS08190	COG0444	Belongs to the ABC transporter superfamily
A8C02_RS08215	COG0346	lactoylglutathione lyase activity
A8C02_RS08220	COG1349	DNA-binding transcription factor activity
A8C02_RS08260	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A8C02_RS08280	COG0300	oxidoreductase activity
A8C02_RS08330	COG0307	riboflavin synthase, alpha
A8C02_RS08335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A8C02_RS08340	COG2814	Major facilitator Superfamily
A8C02_RS08345	COG0583	DNA-binding transcription factor activity
A8C02_RS08355	COG2814	Major facilitator Superfamily
A8C02_RS08370	COG0791	NLP P60 protein
A8C02_RS08375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A8C02_RS08385	COG0346	lactoylglutathione lyase activity
A8C02_RS08390	COG1902	pentaerythritol trinitrate reductase activity
A8C02_RS08395	COG1309	transcriptional regulator
A8C02_RS08400	COG3313	Fe-S protein
A8C02_RS08405	COG4989	oxidoreductase activity
A8C02_RS08410	COG2032	superoxide dismutase activity
A8C02_RS08415	COG1289	transmembrane transporter activity
A8C02_RS08420	COG1566	PFAM secretion protein HlyD family protein
A8C02_RS08435	COG3706	GGDEF domain
A8C02_RS08450	COG3895	Periplasmic Protein
A8C02_RS08465	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
A8C02_RS08470	COG0625	glutathione transferase activity
A8C02_RS08485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A8C02_RS08495	COG4659	FMN binding
A8C02_RS08530	COG2723	6-phospho-beta-galactosidase activity
A8C02_RS08535	COG0673	inositol 2-dehydrogenase activity
A8C02_RS08545	COG2814	Major facilitator Superfamily
A8C02_RS08565	COG3038	cytochrome b561
A8C02_RS08585	COG0583	DNA-binding transcription factor activity
A8C02_RS08590	COG3485	protocatechuate 3,4-dioxygenase
A8C02_RS08595	COG3485	protocatechuate 3,4-dioxygenase
A8C02_RS08600	COG5383	Protein conserved in bacteria
A8C02_RS08605	COG2272	Belongs to the type-B carboxylesterase lipase family
A8C02_RS08620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C02_RS08625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A8C02_RS08630	COG1275	C4-dicarboxylate transporter malic acid transport protein
A8C02_RS08635	COG0500	methyltransferase
A8C02_RS08650	COG3708	Transcriptional regulator
A8C02_RS08650	COG2207	Transcriptional regulator
A8C02_RS08655	COG3135	benzoate transporter
A8C02_RS08660	COG1396	sequence-specific DNA binding
A8C02_RS08670	COG0826	peptidase U32
A8C02_RS08690	COG1294	oxidase, subunit
A8C02_RS08695	COG1271	oxidase subunit
A8C02_RS08700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C02_RS08705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A8C02_RS08710	COG3842	ATPase activity
A8C02_RS08715	COG1176	ABC-type spermidine putrescine transport system, permease component I
A8C02_RS08720	COG1177	transmembrane transport
A8C02_RS08725	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS08760	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS08770	COG0747	negative chemotaxis
A8C02_RS08780	COG3238	Protein conserved in bacteria
A8C02_RS08785	COG1247	-acetyltransferase
A8C02_RS08795	COG2130	NADP-dependent
A8C02_RS08810	COG3691	Protein conserved in bacteria
A8C02_RS08820	COG4772	TonB-dependent receptor
A8C02_RS08845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A8C02_RS08850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C02_RS08855	COG1473	amidohydrolase
A8C02_RS08860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C02_RS08870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C02_RS08875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C02_RS08885	COG0765	amino acid transport
A8C02_RS08890	COG1126	abc transporter atp-binding protein
A8C02_RS08900	COG0625	glutathione transferase activity
A8C02_RS08925	COG2211	Major facilitator Superfamily
A8C02_RS08940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A8C02_RS08945	COG3842	ATPase activity
A8C02_RS08950	COG1840	ABC-type Fe3 transport system, periplasmic component
A8C02_RS08955	COG1178	ABC-type Fe3 transport system permease component
A8C02_RS08960	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A8C02_RS08965	COG2181	nitrate reductase activity
A8C02_RS08970	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A8C02_RS08975	COG1140	nitrate reductase beta subunit
A8C02_RS08980	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A8C02_RS09000	COG1414	Transcriptional regulator
A8C02_RS09005	COG4948	Mandelate Racemase Muconate Lactonizing
A8C02_RS09010	COG4829	muconolactone delta-isomerase
A8C02_RS09015	COG3485	protocatechuate 3,4-dioxygenase
A8C02_RS09025	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A8C02_RS09045	COG3383	formate dehydrogenase (NAD+) activity
A8C02_RS09045	COG0243	molybdopterin cofactor binding
A8C02_RS09050	COG0243	molybdopterin cofactor binding
A8C02_RS09050	COG3383	formate dehydrogenase (NAD+) activity
A8C02_RS09055	COG0437	4 iron, 4 sulfur cluster binding
A8C02_RS09060	COG2864	formate dehydrogenase
A8C02_RS09085	COG2814	Major facilitator Superfamily
A8C02_RS09095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C02_RS09105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C02_RS09115	COG0747	negative chemotaxis
A8C02_RS09120	COG1064	alcohol dehydrogenase
A8C02_RS09140	COG0488	(ABC) transporter
A8C02_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS09190	COG3729	General stress protein
A8C02_RS09200	COG3685	Protein conserved in bacteria
A8C02_RS09210	COG0366	Alpha amylase catalytic
A8C02_RS09220	COG2323	membrane
A8C02_RS09230	COG3111	PFAM Bacterial OB fold (BOF) protein
A8C02_RS09240	COG1764	response to oxidative stress
A8C02_RS09265	COG3781	membrane
A8C02_RS09300	COG0243	molybdopterin cofactor binding
A8C02_RS09305	COG0583	DNA-binding transcription factor activity
A8C02_RS09310	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8C02_RS09315	COG2814	Major facilitator Superfamily
A8C02_RS09320	COG1285	pathogenesis
A8C02_RS09325	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A8C02_RS09335	COG0583	DNA-binding transcription factor activity
A8C02_RS09355	COG0519	Catalyzes the synthesis of GMP from XMP
A8C02_RS09355	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A8C02_RS09395	COG0596	Alpha beta hydrolase
A8C02_RS09405	COG2205	protein histidine kinase activity
A8C02_RS09420	COG0076	glutamate decarboxylase activity
A8C02_RS09425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A8C02_RS09430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8C02_RS09435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C02_RS09440	COG1116	anion transmembrane transporter activity
A8C02_RS09445	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A8C02_RS09455	COG0673	inositol 2-dehydrogenase activity
A8C02_RS09465	COG1609	Transcriptional regulator
A8C02_RS09470	COG3706	GGDEF domain
A8C02_RS09475	COG0402	S-adenosylhomocysteine deaminase activity
A8C02_RS09480	COG1953	Uracil, thiamine, allantoin
A8C02_RS09570	COG0765	amino acid transport
A8C02_RS09580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A8C02_RS09590	COG2070	2-Nitropropane dioxygenase
A8C02_RS09595	COG0583	DNA-binding transcription factor activity
A8C02_RS09605	COG1902	pentaerythritol trinitrate reductase activity
A8C02_RS09610	COG4529	Protein conserved in bacteria
A8C02_RS09615	COG0477	Major facilitator Superfamily
A8C02_RS09645	COG2223	nitrite transmembrane transporter activity
A8C02_RS09655	COG1609	Transcriptional regulator
A8C02_RS09670	COG2200	EAL domain
A8C02_RS09675	COG1546	Belongs to the CinA family
A8C02_RS09680	COG0071	Belongs to the small heat shock protein (HSP20) family
A8C02_RS09700	COG2197	response regulator
A8C02_RS09715	COG2135	peptidase activity
A8C02_RS09720	COG2207	Transcriptional regulator
A8C02_RS09740	COG3708	Transcriptional regulator
A8C02_RS09740	COG2207	Transcriptional regulator
A8C02_RS09745	COG2610	gluconate transmembrane transporter activity
A8C02_RS09750	COG3622	Belongs to the hyi family
A8C02_RS09755	COG0235	Class ii aldolase
A8C02_RS09760	COG3395	kinase activity
A8C02_RS09765	COG2084	Dehydrogenase
A8C02_RS09770	COG1349	DNA-binding transcription factor activity
A8C02_RS09785	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A8C02_RS09790	COG2223	nitrite transmembrane transporter activity
A8C02_RS09825	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A8C02_RS09830	COG0683	leucine binding
A8C02_RS09845	COG1129	ABC transporter
A8C02_RS09860	COG2814	Major facilitator Superfamily
A8C02_RS09865	COG0697	spore germination
A8C02_RS09875	COG4977	sequence-specific DNA binding
A8C02_RS09905	COG2271	Major facilitator Superfamily
A8C02_RS09910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8C02_RS09915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A8C02_RS09925	COG3395	kinase activity
A8C02_RS09930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A8C02_RS09935	COG1349	DNA-binding transcription factor activity
A8C02_RS09940	COG0039	L-malate dehydrogenase activity
A8C02_RS09950	COG0583	DNA-binding transcription factor activity
A8C02_RS09955	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS09970	COG2199	diguanylate cyclase activity
A8C02_RS10020	COG0477	Major facilitator Superfamily
A8C02_RS10030	COG2070	2-Nitropropane dioxygenase
A8C02_RS10035	COG2011	ABC-type metal ion transport system permease component
A8C02_RS10055	COG4628	conserved protein (DUF2132)
A8C02_RS10070	COG2207	Transcriptional regulator
A8C02_RS10100	COG2233	PERMEase
A8C02_RS10105	COG3648	Uricase
A8C02_RS10105	COG3195	allantoin biosynthetic process
A8C02_RS10110	COG2351	hydroxyisourate hydrolase activity
A8C02_RS10115	COG1396	sequence-specific DNA binding
A8C02_RS10120	COG3550	peptidyl-serine autophosphorylation
A8C02_RS10125	COG1649	PFAM Uncharacterised BCR, COG1649
A8C02_RS10135	COG3188	usher protein
A8C02_RS10170	COG5001	Diguanylate cyclase
A8C02_RS10170	COG3300	MHYT domain
A8C02_RS10175	COG2819	hydrolase of the alpha beta superfamily
A8C02_RS10195	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C02_RS10195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C02_RS10200	COG2814	Major facilitator Superfamily
A8C02_RS10215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C02_RS10215	COG1263	PTS System
A8C02_RS10220	COG2186	Transcriptional regulator
A8C02_RS10230	COG0583	DNA-binding transcription factor activity
A8C02_RS10240	COG3835	regulator
A8C02_RS10245	COG1929	Belongs to the glycerate kinase type-1 family
A8C02_RS10290	COG0738	Major facilitator superfamily
A8C02_RS10295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C02_RS10300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A8C02_RS10305	COG1349	DNA-binding transcription factor activity
A8C02_RS10320	COG1349	DNA-binding transcription factor activity
A8C02_RS10345	COG2801	Transposase and inactivated derivatives
A8C02_RS10350	COG2801	Transposase and inactivated derivatives
A8C02_RS10360	COG0667	Aldo Keto reductase
A8C02_RS10365	COG3386	PFAM SMP-30 Gluconolaconase
A8C02_RS10370	COG0667	Aldo Keto reductase
A8C02_RS10375	COG0667	Aldo Keto reductase
A8C02_RS10390	COG4221	oxidoreductase activity
A8C02_RS10395	COG1802	Transcriptional regulator
A8C02_RS10400	COG0589	response to stress
A8C02_RS10405	COG0246	Mannitol dehydrogenase
A8C02_RS10410	COG2271	Major facilitator Superfamily
A8C02_RS10425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C02_RS10445	COG0437	4 iron, 4 sulfur cluster binding
A8C02_RS10450	COG3302	dmso reductase anchor subunit
A8C02_RS10465	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A8C02_RS10470	COG1940	carbohydrate kinase activity
A8C02_RS10475	COG0583	DNA-binding transcription factor activity
A8C02_RS10480	COG2814	Major facilitator Superfamily
A8C02_RS10485	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A8C02_RS10505	COG3591	Belongs to the peptidase S1B family
A8C02_RS10525	COG0628	permease
A8C02_RS10555	COG0679	Auxin Efflux Carrier
A8C02_RS10565	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A8C02_RS10605	COG3290	protein histidine kinase activity
A8C02_RS10610	COG4565	transcriptional regulatory protein
A8C02_RS10635	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A8C02_RS10635	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A8C02_RS10645	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8C02_RS10650	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A8C02_RS10660	COG0183	Belongs to the thiolase family
A8C02_RS10665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A8C02_RS10675	COG1414	Transcriptional regulator
A8C02_RS10680	COG2840	Smr protein MutS2
A8C02_RS10685	COG0583	DNA-binding transcription factor activity
A8C02_RS10695	COG1473	amidohydrolase
A8C02_RS10700	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A8C02_RS10715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A8C02_RS10730	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A8C02_RS10735	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A8C02_RS10760	COG0531	amino acid
A8C02_RS10770	COG3136	membrane protein required for alginate biosynthesis
A8C02_RS10775	COG0745	RESPONSE REGULATOR receiver
A8C02_RS10785	COG2205	protein histidine kinase activity
A8C02_RS10795	COG0114	fumarate hydratase activity
A8C02_RS10800	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A8C02_RS10800	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A8C02_RS10805	COG1482	cell wall glycoprotein biosynthetic process
A8C02_RS10810	COG5339	Protein conserved in bacteria
A8C02_RS10815	COG1609	Transcriptional regulator
A8C02_RS10820	COG1263	PTS System
A8C02_RS10820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C02_RS10825	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A8C02_RS10850	COG2391	methyltransferase activity
A8C02_RS10855	COG0425	Belongs to the sulfur carrier protein TusA family
A8C02_RS10860	COG5562	phage envelope protein
A8C02_RS10865	COG0401	homolog of Blt101
A8C02_RS10870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A8C02_RS10885	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A8C02_RS10890	COG0477	Major facilitator Superfamily
A8C02_RS10895	COG1113	amino acid transport
A8C02_RS10900	COG2988	succinylglutamate desuccinylase activity
A8C02_RS10905	COG3724	N-succinylarginine dihydrolase activity
A8C02_RS10910	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS10915	COG3138	arginine N-succinyltransferase
A8C02_RS10920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A8C02_RS10930	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A8C02_RS10935	COG0667	Aldo Keto reductase
A8C02_RS10940	COG0583	DNA-binding transcription factor activity
A8C02_RS10965	COG4122	O-methyltransferase activity
A8C02_RS10970	COG1643	Atp-dependent helicase
A8C02_RS10985	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A8C02_RS10990	COG3327	negative regulation of DNA-templated transcription, initiation
A8C02_RS10995	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A8C02_RS11000	COG0183	Belongs to the thiolase family
A8C02_RS11005	COG2050	protein possibly involved in aromatic compounds catabolism
A8C02_RS11010	COG1250	3-hydroxyacyl-CoA dehydrogenase
A8C02_RS11015	COG1024	Enoyl-CoA hydratase
A8C02_RS11020	COG1024	Enoyl-CoA hydratase
A8C02_RS11025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8C02_RS11030	COG2151	metal-sulfur cluster biosynthetic enzyme
A8C02_RS11035	COG3396	Phenylacetate-CoA oxygenase
A8C02_RS11040	COG3460	Phenylacetate-CoA oxygenase
A8C02_RS11045	COG3396	Phenylacetate-CoA oxygenase
A8C02_RS11050	COG2030	dehydratase
A8C02_RS11050	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS11085	COG2072	flavoprotein involved in K transport
A8C02_RS11090	COG0583	DNA-binding transcription factor activity
A8C02_RS11095	COG1126	abc transporter atp-binding protein
A8C02_RS11105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C02_RS11120	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS11125	COG2963	transposase activity
A8C02_RS11130	COG2801	Transposase and inactivated derivatives
A8C02_RS11135	COG2963	transposase activity
A8C02_RS11145	COG2963	transposase activity
A8C02_RS11150	COG2801	Transposase and inactivated derivatives
A8C02_RS11170	COG2207	Transcriptional regulator
A8C02_RS11175	COG3784	Protein of unknown function (DUF1318)
A8C02_RS11185	COG2911	Protein conserved in bacteria
A8C02_RS11190	COG0586	Pfam SNARE associated Golgi protein
A8C02_RS11195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A8C02_RS11200	COG3187	Heat shock protein
A8C02_RS11205	COG3042	response to heat
A8C02_RS11210	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A8C02_RS11210	COG0674	pyruvate-flavodoxin oxidoreductase activity
A8C02_RS11210	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A8C02_RS11210	COG1013	pyruvate-flavodoxin oxidoreductase activity
A8C02_RS11215	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A8C02_RS11225	COG0589	response to stress
A8C02_RS11235	COG0513	Belongs to the DEAD box helicase family
A8C02_RS11245	COG1349	DNA-binding transcription factor activity
A8C02_RS11250	COG0673	inositol 2-dehydrogenase activity
A8C02_RS11270	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS11275	COG0583	DNA-binding transcription factor activity
A8C02_RS11290	COG0656	L-ascorbic acid biosynthetic process
A8C02_RS11320	COG4166	transmembrane transport
A8C02_RS11330	COG2866	Carboxypeptidase
A8C02_RS11335	COG4948	Mandelate Racemase Muconate Lactonizing
A8C02_RS11340	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A8C02_RS11345	COG3180	Ammonia monooxygenase
A8C02_RS11355	COG1486	melibiose metabolic process
A8C02_RS11360	COG0583	DNA-binding transcription factor activity
A8C02_RS11370	COG3106	COG3106 Predicted ATPase
A8C02_RS11380	COG1983	PspC domain protein
A8C02_RS11390	COG1842	Phage shock protein A
A8C02_RS11395	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A8C02_RS11400	COG1473	amidohydrolase
A8C02_RS11415	COG0702	epimerase
A8C02_RS11430	COG4171	peptide transport system, permease
A8C02_RS11445	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A8C02_RS11455	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A8C02_RS11465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8C02_RS11465	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8C02_RS11480	COG1349	DNA-binding transcription factor activity
A8C02_RS11495	COG0023	Translation Initiation Factor
A8C02_RS11505	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
A8C02_RS11510	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
A8C02_RS11515	COG0671	phosphoesterase, PA-phosphatase related
A8C02_RS11525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A8C02_RS11565	COG0616	signal peptide processing
A8C02_RS11575	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS11580	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A8C02_RS11590	COG0583	DNA-binding transcription factor activity
A8C02_RS11600	COG0009	L-threonylcarbamoyladenylate synthase
A8C02_RS11610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A8C02_RS11615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A8C02_RS11615	COG0512	Glutamine amidotransferase of anthranilate synthase
A8C02_RS11620	COG0135	phosphoribosylanthranilate isomerase activity
A8C02_RS11620	COG0134	indole-3-glycerol-phosphate synthase activity
A8C02_RS11655	COG4774	siderophore transport
A8C02_RS11665	COG3047	cAMP biosynthetic process
A8C02_RS11670	COG0727	PFAM Uncharacterised protein family (UPF0153)
A8C02_RS11700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8C02_RS11705	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS11710	COG1988	membrane-bound metal-dependent
A8C02_RS11715	COG1823	symporter activity
A8C02_RS11725	COG0753	catalase activity
A8C02_RS11735	COG1486	melibiose metabolic process
A8C02_RS11740	COG1917	Cupin 2, conserved barrel domain protein
A8C02_RS11740	COG2169	Transcriptional regulator
A8C02_RS11745	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8C02_RS11750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C02_RS11760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C02_RS11765	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8C02_RS11775	COG0322	excinuclease ABC activity
A8C02_RS11780	COG3678	ATP-independent chaperone mediated protein folding
A8C02_RS11795	COG3724	N-succinylarginine dihydrolase activity
A8C02_RS11805	COG3138	arginine N-succinyltransferase
A8C02_RS11815	COG0708	Exodeoxyribonuclease III
A8C02_RS11820	COG0398	Pfam SNARE associated Golgi protein
A8C02_RS11825	COG0398	Pfam SNARE associated Golgi protein
A8C02_RS11830	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A8C02_RS11835	COG4134	Bacterial extracellular solute-binding protein
A8C02_RS11840	COG4135	transport system, permease component
A8C02_RS11845	COG4136	ATPase activity
A8C02_RS11850	COG2897	thiosulfate sulfurtransferase activity
A8C02_RS11855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A8C02_RS11860	COG0494	nUDIX hydrolase
A8C02_RS11870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A8C02_RS11875	COG0604	alcohol dehydrogenase
A8C02_RS11875	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS11875	COG3321	synthase
A8C02_RS11880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A8C02_RS11885	COG0709	Synthesizes selenophosphate from selenide and ATP
A8C02_RS11900	COG0778	Nitroreductase
A8C02_RS11905	COG0616	signal peptide processing
A8C02_RS11910	COG0252	asparaginase activity
A8C02_RS11915	COG1335	isochorismatase
A8C02_RS11930	COG3139	Protein of unknown function (DUF1315)
A8C02_RS11950	COG0656	L-ascorbic acid biosynthetic process
A8C02_RS11955	COG3713	MltA-interacting MipA family protein
A8C02_RS11960	COG2766	serine protein kinase
A8C02_RS11975	COG0386	Belongs to the glutathione peroxidase family
A8C02_RS12000	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS12005	COG0583	DNA-binding transcription factor activity
A8C02_RS12010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A8C02_RS12015	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A8C02_RS12025	COG0859	PFAM glycosyl transferase family 9
A8C02_RS12030	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A8C02_RS12040	COG2207	Transcriptional regulator
A8C02_RS12045	COG2807	transmembrane transport
A8C02_RS12050	COG0504	CTP synthase activity
A8C02_RS12055	COG1683	Conserved Protein
A8C02_RS12060	COG3189	MarR family transcriptional regulator
A8C02_RS12065	COG3042	response to heat
A8C02_RS12190	COG4695	Portal protein
A8C02_RS12245	COG4974	Belongs to the 'phage' integrase family
A8C02_RS12250	COG2203	Gaf domain
A8C02_RS12250	COG2199	diguanylate cyclase activity
A8C02_RS12265	COG3182	Iron-regulated membrane protein
A8C02_RS12275	COG1560	Kdo2-lipid A biosynthetic process
A8C02_RS12295	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A8C02_RS12300	COG3706	GGDEF domain
A8C02_RS12305	COG0583	DNA-binding transcription factor activity
A8C02_RS12310	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A8C02_RS12345	COG1294	oxidase, subunit
A8C02_RS12350	COG1271	oxidase subunit
A8C02_RS12355	COG3546	catalase activity
A8C02_RS12360	COG3685	Protein conserved in bacteria
A8C02_RS12365	COG3685	Protein conserved in bacteria
A8C02_RS12370	COG3729	General stress protein
A8C02_RS12380	COG1063	alcohol dehydrogenase
A8C02_RS12385	COG3813	Protein conserved in bacteria
A8C02_RS12410	COG0640	Transcriptional regulator
A8C02_RS12415	COG0538	isocitrate dehydrogenase activity
A8C02_RS12420	COG1187	pseudouridine synthase activity
A8C02_RS12440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A8C02_RS12460	COG2205	protein histidine kinase activity
A8C02_RS12465	COG2850	peptidyl-arginine hydroxylation
A8C02_RS12485	COG1177	transmembrane transport
A8C02_RS12500	COG0318	PFAM AMP-dependent synthetase and ligase
A8C02_RS12505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A8C02_RS12510	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A8C02_RS12515	COG0698	ribose 5-phosphate isomerase
A8C02_RS12530	COG3395	kinase activity
A8C02_RS12545	COG2390	Transcriptional regulator
A8C02_RS12555	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A8C02_RS12565	COG4591	ABC-type transport system involved in lipoprotein release permease component
A8C02_RS12575	COG4591	ABC-type transport system involved in lipoprotein release permease component
A8C02_RS12585	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A8C02_RS12590	COG1376	ErfK ybiS ycfS ynhG family protein
A8C02_RS12590	COG1388	LysM domain
A8C02_RS12605	COG1309	transcriptional regulator
A8C02_RS12620	COG3134	Outer membrane lipoprotein
A8C02_RS12625	COG1252	NADH dehydrogenase
A8C02_RS12650	COG5633	Lipoprotein
A8C02_RS12655	COG0537	adenosine 5'-monophosphoramidase activity
A8C02_RS12665	COG0084	hydrolase, TatD family'
A8C02_RS12670	COG0470	DNA polymerase III
A8C02_RS12680	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A8C02_RS12685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A8C02_RS12690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A8C02_RS12705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A8C02_RS12725	COG1399	metal-binding, possibly nucleic acid-binding protein
A8C02_RS12740	COG1530	ribonuclease E activity
A8C02_RS12745	COG0583	DNA-binding transcription factor activity
A8C02_RS12750	COG2814	Major facilitator Superfamily
A8C02_RS12770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C02_RS12820	COG1560	Kdo2-lipid A biosynthetic process
A8C02_RS12835	COG5645	(Lipo)protein
A8C02_RS12870	COG3381	protein complex oligomerization
A8C02_RS12895	COG0583	DNA-binding transcription factor activity
A8C02_RS12905	COG1335	isochorismatase
A8C02_RS12915	COG1702	phosphate starvation-inducible protein PhoH
A8C02_RS12935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C02_RS12945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A8C02_RS12960	COG1309	transcriptional regulator
A8C02_RS12995	COG2233	PERMEase
A8C02_RS13005	COG3729	General stress protein
A8C02_RS13035	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS13050	COG0531	amino acid
A8C02_RS13055	COG0174	glutamine synthetase
A8C02_RS13060	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A8C02_RS13065	COG1917	Cupin 2, conserved barrel domain protein
A8C02_RS13065	COG1396	sequence-specific DNA binding
A8C02_RS13070	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS13075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A8C02_RS13080	COG0583	DNA-binding transcription factor activity
A8C02_RS13085	COG0473	3-isopropylmalate dehydrogenase activity
A8C02_RS13090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A8C02_RS13095	COG4638	Rieske (2fe-2S)
A8C02_RS13100	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS13105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8C02_RS13115	COG2200	EAL domain
A8C02_RS13120	COG2200	EAL domain
A8C02_RS13135	COG0670	Belongs to the BI1 family
A8C02_RS13150	COG2207	Transcriptional regulator
A8C02_RS13155	COG1881	PFAM PEBP family protein
A8C02_RS13170	COG1832	CoA-binding protein
A8C02_RS13180	COG0210	DNA helicase
A8C02_RS13185	COG3304	Inner membrane component domain
A8C02_RS13190	COG1289	transmembrane transporter activity
A8C02_RS13195	COG3070	regulator of competence-specific genes
A8C02_RS13215	COG1067	ATP-dependent peptidase activity
A8C02_RS13225	COG3130	regulation of translation
A8C02_RS13230	COG3009	Protein conserved in bacteria
A8C02_RS13235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A8C02_RS13235	COG3008	intermembrane lipid transfer
A8C02_RS13240	COG2995	paraquat-inducible protein a
A8C02_RS13245	COG0488	(ABC) transporter
A8C02_RS13255	COG3217	Mosc domain protein beta barrel domain protein
A8C02_RS13255	COG0633	Ferredoxin
A8C02_RS13270	COG0431	NADPH-dependent FMN reductase
A8C02_RS13275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A8C02_RS13280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C02_RS13285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C02_RS13295	COG0308	aminopeptidase N
A8C02_RS13310	COG1473	amidohydrolase
A8C02_RS13320	COG0814	amino acid
A8C02_RS13330	COG1522	sequence-specific DNA binding
A8C02_RS13345	COG1448	Aminotransferase
A8C02_RS13350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A8C02_RS13355	COG3108	Peptidase M15
A8C02_RS13360	COG2989	Protein conserved in bacteria
A8C02_RS13370	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
A8C02_RS13380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A8C02_RS13385	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A8C02_RS13390	COG3173	Aminoglycoside phosphotransferase
A8C02_RS13405	COG3214	Protein conserved in bacteria
A8C02_RS13420	COG2333	competence protein COMEC
A8C02_RS13420	COG0658	competence protein
A8C02_RS13430	COG0539	negative regulation of cytoplasmic translation
A8C02_RS13450	COG2323	membrane
A8C02_RS13455	COG1944	ATP diphosphatase activity
A8C02_RS13460	COG2116	formate transmembrane transporter activity
A8C02_RS13465	COG1882	Formate acetyltransferase
A8C02_RS13470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8C02_RS13475	COG0477	Major facilitator Superfamily
A8C02_RS13485	COG3302	dmso reductase anchor subunit
A8C02_RS13490	COG0437	4 iron, 4 sulfur cluster binding
A8C02_RS13495	COG0243	molybdopterin cofactor binding
A8C02_RS13505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A8C02_RS13515	COG1178	ABC-type Fe3 transport system permease component
A8C02_RS13515	COG1674	ftsk spoiiie
A8C02_RS13530	COG0492	ferredoxin-NADP+ reductase activity
A8C02_RS13535	COG4988	ABC transporter
A8C02_RS13540	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A8C02_RS13555	COG0542	response to heat
A8C02_RS13565	COG1278	Cold shock
A8C02_RS13575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C02_RS13580	COG3593	DNA synthesis involved in DNA repair
A8C02_RS13590	COG2431	L-lysine efflux transmembrane transporter activity
A8C02_RS13600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A8C02_RS13610	COG0028	Belongs to the TPP enzyme family
A8C02_RS13615	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
A8C02_RS13620	COG0702	epimerase
A8C02_RS13625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A8C02_RS13630	COG3023	N-Acetylmuramoyl-L-alanine amidase
A8C02_RS13635	COG3706	GGDEF domain
A8C02_RS13635	COG4251	negative regulation of phosphorylation
A8C02_RS13635	COG2203	Gaf domain
A8C02_RS13635	COG5001	Diguanylate cyclase
A8C02_RS13645	COG1126	abc transporter atp-binding protein
A8C02_RS13650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C02_RS13655	COG4215	(ABC) transporter
A8C02_RS13660	COG4160	amino acid transport
A8C02_RS13665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C02_RS13670	COG5002	protein histidine kinase activity
A8C02_RS13675	COG0745	RESPONSE REGULATOR receiver
A8C02_RS13690	COG1177	transmembrane transport
A8C02_RS13695	COG1176	ABC-type spermidine putrescine transport system, permease component I
A8C02_RS13700	COG3842	ATPase activity
A8C02_RS13705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A8C02_RS13720	COG0778	Nitroreductase
A8C02_RS13750	COG3226	Transcriptional regulator
A8C02_RS13755	COG0738	Major facilitator superfamily
A8C02_RS13760	COG0561	phosphatase activity
A8C02_RS13765	COG2814	Major facilitator Superfamily
A8C02_RS13770	COG0671	phosphoesterase, PA-phosphatase related
A8C02_RS13775	COG1349	DNA-binding transcription factor activity
A8C02_RS13780	COG1686	Belongs to the peptidase S11 family
A8C02_RS13790	COG0625	glutathione transferase activity
A8C02_RS13795	COG2133	pyrroloquinoline quinone binding
A8C02_RS13805	COG2223	nitrite transmembrane transporter activity
A8C02_RS13825	COG0747	negative chemotaxis
A8C02_RS13840	COG0303	'Molybdopterin
A8C02_RS13845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A8C02_RS13850	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A8C02_RS13855	COG1882	Formate acetyltransferase
A8C02_RS13860	COG0561	phosphatase activity
A8C02_RS13870	COG1609	Transcriptional regulator
A8C02_RS13875	COG2271	Major facilitator Superfamily
A8C02_RS13885	COG0488	(ABC) transporter
A8C02_RS13890	COG2365	Tyrosine phosphatase family
A8C02_RS13895	COG1376	ErfK ybiS ycfS ynhG family protein
A8C02_RS13900	COG2188	Transcriptional regulator
A8C02_RS13905	COG2723	6-phospho-beta-galactosidase activity
A8C02_RS13910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A8C02_RS13925	COG2194	sulfuric ester hydrolase activity
A8C02_RS13930	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A8C02_RS13950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C02_RS13955	COG0765	amino acid transport
A8C02_RS13960	COG1126	abc transporter atp-binding protein
A8C02_RS13965	COG0668	transmembrane transport
A8C02_RS13975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A8C02_RS13985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A8C02_RS13995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A8C02_RS14000	COG1199	ATP-dependent helicase activity
A8C02_RS14005	COG0513	Belongs to the DEAD box helicase family
A8C02_RS14010	COG3958	Transketolase
A8C02_RS14015	COG3959	Transketolase, thiamine diphosphate binding domain
A8C02_RS14020	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS14025	COG2271	Major facilitator Superfamily
A8C02_RS14040	COG0583	DNA-binding transcription factor activity
A8C02_RS14045	COG1309	transcriptional regulator
A8C02_RS14050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C02_RS14055	COG1131	(ABC) transporter
A8C02_RS14060	COG0842	Transport permease protein
A8C02_RS14065	COG0842	Transport permease protein
A8C02_RS14075	COG3568	Endonuclease Exonuclease Phosphatase
A8C02_RS14080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A8C02_RS14085	COG0392	lysyltransferase activity
A8C02_RS14090	COG0670	Belongs to the BI1 family
A8C02_RS14095	COG0314	molybdopterin synthase activity
A8C02_RS14100	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A8C02_RS14110	COG0521	Mo-molybdopterin cofactor biosynthetic process
A8C02_RS14130	COG0745	RESPONSE REGULATOR receiver
A8C02_RS14135	COG0642	Histidine kinase
A8C02_RS14165	COG2226	methyltransferase
A8C02_RS14180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A8C02_RS14185	COG1881	PFAM PEBP family protein
A8C02_RS14220	COG4677	pectinesterase activity
A8C02_RS14230	COG0589	response to stress
A8C02_RS14235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C02_RS14270	COG0789	Transcriptional regulator
A8C02_RS14275	COG2200	EAL domain
A8C02_RS14300	COG0561	phosphatase activity
A8C02_RS14310	COG4149	molybdate abc transporter
A8C02_RS14315	COG0725	ABC transporter, periplasmic molybdate-binding protein
A8C02_RS14325	COG2005	Transcriptional regulator
A8C02_RS14325	COG3585	molybdate ion transport
A8C02_RS14330	COG1119	ATPase activity
A8C02_RS14345	COG1085	galactose-1-phosphate uridylyltransferase
A8C02_RS14355	COG2017	converts alpha-aldose to the beta-anomer
A8C02_RS14365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A8C02_RS14380	COG3201	nicotinamide mononucleotide transporter
A8C02_RS14385	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A8C02_RS14445	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
A8C02_RS14450	COG2885	chlorophyll binding
A8C02_RS14460	COG3064	Membrane
A8C02_RS14465	COG0848	biopolymer transport protein
A8C02_RS14470	COG0811	peptide transport
A8C02_RS14475	COG0824	Thioesterase
A8C02_RS14480	COG3790	cyd operon protein YbgE
A8C02_RS14485	COG4890	Cyd operon protein YbgT
A8C02_RS14490	COG1294	oxidase, subunit
A8C02_RS14495	COG1271	oxidase subunit
A8C02_RS14505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A8C02_RS14515	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8C02_RS14520	COG0567	Dehydrogenase, E1 component
A8C02_RS14525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A8C02_RS14530	COG1053	succinate dehydrogenase
A8C02_RS14535	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A8C02_RS14540	COG2009	succinate dehydrogenase
A8C02_RS14580	COG1984	allophanate hydrolase subunit 2
A8C02_RS14585	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A8C02_RS14600	COG0415	Belongs to the DNA photolyase family
A8C02_RS14625	COG2205	protein histidine kinase activity
A8C02_RS14630	COG0745	RESPONSE REGULATOR receiver
A8C02_RS14640	COG0033	Phosphoglucomutase
A8C02_RS14655	COG0596	Alpha beta hydrolase
A8C02_RS14670	COG0735	belongs to the Fur family
A8C02_RS14705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A8C02_RS14710	COG1940	carbohydrate kinase activity
A8C02_RS14710	COG1846	Transcriptional regulator
A8C02_RS14715	COG0647	UMP catabolic process
A8C02_RS14720	COG0367	asparagine synthase
A8C02_RS14760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8C02_RS14770	COG1702	phosphate starvation-inducible protein PhoH
A8C02_RS14795	COG0765	amino acid transport
A8C02_RS14800	COG0765	amino acid transport
A8C02_RS14805	COG1126	abc transporter atp-binding protein
A8C02_RS14825	COG2888	peptidyl-tyrosine sulfation
A8C02_RS14840	COG1466	dna polymerase III delta subunit
A8C02_RS14855	COG0799	negative regulation of ribosome biogenesis
A8C02_RS14865	COG0768	penicillin binding
A8C02_RS14870	COG0772	Belongs to the SEDS family
A8C02_RS14875	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A8C02_RS14880	COG1686	Belongs to the peptidase S11 family
A8C02_RS14895	COG0583	DNA-binding transcription factor activity
A8C02_RS14910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A8C02_RS14930	COG3069	C4-dicarboxylate transmembrane transporter activity
A8C02_RS14935	COG3719	Belongs to the RNase T2 family
A8C02_RS14940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A8C02_RS14960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A8C02_RS14965	COG0583	DNA-binding transcription factor activity
A8C02_RS14970	COG3969	phosphoadenosine phosphosulfate
A8C02_RS14975	COG1475	DNA binding
A8C02_RS14980	COG0436	Aminotransferase
A8C02_RS15005	COG1129	ABC transporter
A8C02_RS15010	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS15015	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS15025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8C02_RS15040	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A8C02_RS15050	COG0402	S-adenosylhomocysteine deaminase activity
A8C02_RS15060	COG0483	inositol monophosphate 1-phosphatase activity
A8C02_RS15065	COG2271	Major facilitator Superfamily
A8C02_RS15095	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS15100	COG1129	ABC transporter
A8C02_RS15105	COG0371	Dehydrogenase
A8C02_RS15110	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS15125	COG2879	small protein
A8C02_RS15130	COG1966	Carbon starvation protein
A8C02_RS15140	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS15145	COG1535	isochorismatase
A8C02_RS15145	COG3433	isochorismatase activity
A8C02_RS15150	COG1021	2,3-dihydroxybenzoate-AMP ligase
A8C02_RS15155	COG1169	isochorismate synthase
A8C02_RS15160	COG4592	Periplasmic binding protein
A8C02_RS15170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C02_RS15175	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C02_RS15180	COG1120	ATPase activity
A8C02_RS15185	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A8C02_RS15185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A8C02_RS15190	COG3251	PFAM MbtH domain protein
A8C02_RS15195	COG2382	esterase
A8C02_RS15200	COG4771	TonB-dependent receptor
A8C02_RS15210	COG3958	Transketolase
A8C02_RS15215	COG3959	Transketolase, thiamine diphosphate binding domain
A8C02_RS15220	COG2390	Transcriptional regulator
A8C02_RS15225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A8C02_RS15230	COG1879	ABC-type sugar transport system periplasmic component
A8C02_RS15240	COG1129	ABC transporter
A8C02_RS15245	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS15255	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS15265	COG0583	DNA-binding transcription factor activity
A8C02_RS15270	COG0668	transmembrane transport
A8C02_RS15280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A8C02_RS15305	COG0747	negative chemotaxis
A8C02_RS15310	COG0601	transmembrane transport
A8C02_RS15315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C02_RS15320	COG0444	Belongs to the ABC transporter superfamily
A8C02_RS15325	COG4608	Belongs to the ABC transporter superfamily
A8C02_RS15340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A8C02_RS15345	COG4221	oxidoreductase activity
A8C02_RS15355	COG4215	(ABC) transporter
A8C02_RS15360	COG0765	amino acid transport
A8C02_RS15365	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
A8C02_RS15380	COG0697	spore germination
A8C02_RS15395	COG4608	Belongs to the ABC transporter superfamily
A8C02_RS15400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C02_RS15410	COG4166	transmembrane transport
A8C02_RS15420	COG3698	Phosphodiester glycosidase
A8C02_RS15465	COG2315	Protein conserved in bacteria
A8C02_RS15470	COG0778	Nitroreductase
A8C02_RS15495	COG0477	Major facilitator Superfamily
A8C02_RS15500	COG0668	transmembrane transport
A8C02_RS15515	COG0673	inositol 2-dehydrogenase activity
A8C02_RS15525	COG2211	Major facilitator Superfamily
A8C02_RS15530	COG1113	amino acid transport
A8C02_RS15545	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS15550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A8C02_RS15560	COG0531	amino acid
A8C02_RS15605	COG0667	Aldo Keto reductase
A8C02_RS15610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C02_RS15615	COG1473	amidohydrolase
A8C02_RS15650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C02_RS15655	COG1120	ATPase activity
A8C02_RS15660	COG1566	PFAM secretion protein HlyD family protein
A8C02_RS15715	COG4211	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS15720	COG1129	ABC transporter
A8C02_RS15735	COG0673	inositol 2-dehydrogenase activity
A8C02_RS15765	COG3104	oligopeptide transport
A8C02_RS15770	COG1982	Orn Lys Arg decarboxylase major
A8C02_RS15775	COG0531	amino acid
A8C02_RS15780	COG3710	Transcriptional regulator
A8C02_RS15790	COG1560	Kdo2-lipid A biosynthetic process
A8C02_RS15805	COG3188	usher protein
A8C02_RS15810	COG3121	Chaperone
A8C02_RS15815	COG3539	Fimbrial protein
A8C02_RS15930	COG4386	tail sheath protein
A8C02_RS15965	COG0616	signal peptide processing
A8C02_RS16005	COG3772	lysozyme
A8C02_RS16035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A8C02_RS16155	COG0582	viral genome integration into host DNA
A8C02_RS16170	COG2501	S4 domain
A8C02_RS16180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A8C02_RS16195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A8C02_RS16200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A8C02_RS16220	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A8C02_RS16225	COG4181	ATPase activity
A8C02_RS16230	COG2755	lipolytic protein G-D-S-L family
A8C02_RS16235	COG0300	oxidoreductase activity
A8C02_RS16240	COG3118	belongs to the thioredoxin family
A8C02_RS16245	COG0390	transport system, permease component
A8C02_RS16250	COG4619	ABC transporter
A8C02_RS16255	COG0330	HflC and HflK could
A8C02_RS16260	COG1585	Membrane protein implicated in regulation of membrane protease activity
A8C02_RS16275	COG3735	TraB family
A8C02_RS16280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A8C02_RS16290	COG2223	nitrite transmembrane transporter activity
A8C02_RS16305	COG4651	solute:proton antiporter activity
A8C02_RS16305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A8C02_RS16310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C02_RS16350	COG2832	Protein of unknown function (DUF454)
A8C02_RS16355	COG3923	Primosomal replication protein n
A8C02_RS16370	COG3264	Mechanosensitive ion channel
A8C02_RS16370	COG1196	nuclear chromosome segregation
A8C02_RS16375	COG1309	transcriptional regulator
A8C02_RS16380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C02_RS16385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8C02_RS16400	COG0110	maltose O-acetyltransferase activity
A8C02_RS16450	COG1874	Beta-galactosidase
A8C02_RS16455	COG3867	Arabinogalactan endo-beta-1,4-galactanase
A8C02_RS16460	COG3833	ABC-type maltose transport systems, permease component
A8C02_RS16465	COG1175	transmembrane transport
A8C02_RS16470	COG2182	Extracellular solute-binding protein
A8C02_RS16485	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A8C02_RS16500	COG2364	Membrane
A8C02_RS16570	COG0210	DNA helicase
A8C02_RS16590	COG3695	enzyme binding
A8C02_RS16595	COG3126	Type III secretion system lipoprotein chaperone (YscW)
A8C02_RS16600	COG1946	Acyl-CoA thioesterase
A8C02_RS16605	COG0004	ammonium transporteR
A8C02_RS16610	COG0347	Belongs to the P(II) protein family
A8C02_RS16615	COG1132	(ABC) transporter
A8C02_RS16620	COG1132	(ABC) transporter
A8C02_RS16625	COG1522	sequence-specific DNA binding
A8C02_RS16640	COG4533	DNA binding
A8C02_RS16650	COG0824	Thioesterase
A8C02_RS16655	COG1555	photosystem II stabilization
A8C02_RS16660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8C02_RS16665	COG0776	regulation of translation
A8C02_RS16670	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A8C02_RS16690	COG0271	Belongs to the BolA IbaG family
A8C02_RS16695	COG3056	Lipoprotein
A8C02_RS16700	COG2223	nitrite transmembrane transporter activity
A8C02_RS16705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A8C02_RS16710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A8C02_RS16715	COG1845	cytochrome c oxidase, subunit III
A8C02_RS16720	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A8C02_RS16735	COG1414	Transcriptional regulator
A8C02_RS16740	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A8C02_RS16745	COG1053	succinate dehydrogenase
A8C02_RS16755	COG1053	succinate dehydrogenase
A8C02_RS16770	COG0673	inositol 2-dehydrogenase activity
A8C02_RS16775	COG2814	Major facilitator Superfamily
A8C02_RS16785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A8C02_RS16790	COG0693	protein deglycase activity
A8C02_RS16810	COG0142	geranyltranstransferase activity
A8C02_RS16820	COG0667	Aldo Keto reductase
A8C02_RS16825	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A8C02_RS16830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A8C02_RS16845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A8C02_RS16845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A8C02_RS16855	COG4238	major outer membrane lipoprotein
A8C02_RS16875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A8C02_RS16880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A8C02_RS16885	COG1862	Preprotein translocase
A8C02_RS16910	COG0450	alkyl hydroperoxide reductase
A8C02_RS16920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C02_RS16945	COG1228	amidohydrolase
A8C02_RS16955	COG1335	isochorismatase
A8C02_RS16960	COG0583	DNA-binding transcription factor activity
A8C02_RS16965	COG0366	Alpha amylase catalytic
A8C02_RS16990	COG0420	3'-5' exonuclease activity
A8C02_RS16995	COG0419	ATPase involved in DNA repair
A8C02_RS17000	COG1940	carbohydrate kinase activity
A8C02_RS17015	COG4126	flavin adenine dinucleotide binding
A8C02_RS17025	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A8C02_RS17030	COG3416	Protein conserved in bacteria
A8C02_RS17040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A8C02_RS17050	COG1785	Belongs to the alkaline phosphatase family
A8C02_RS17090	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A8C02_RS17095	COG1335	isochorismatase
A8C02_RS17100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A8C02_RS17105	COG0113	porphobilinogen synthase activity
A8C02_RS17115	COG2175	clavaminate synthase activity
A8C02_RS17120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A8C02_RS17125	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A8C02_RS17130	COG4521	taurine ABC transporter
A8C02_RS17135	COG2040	homocysteine
A8C02_RS17140	COG0833	amino acid
A8C02_RS17155	COG4303	Ethanolamine ammonia lyase large subunit
A8C02_RS17160	COG4302	ethanolamine ammonia-lyase activity
A8C02_RS17200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C02_RS17205	COG1126	abc transporter atp-binding protein
A8C02_RS17210	COG4597	amino acid ABC transporter
A8C02_RS17215	COG0765	amino acid transport
A8C02_RS17230	COG3188	usher protein
A8C02_RS17255	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
A8C02_RS17265	COG3639	organic phosphonate transmembrane transporter activity
A8C02_RS17285	COG0791	NLP P60 protein
A8C02_RS17320	COG3039	Transposase
A8C02_RS17330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A8C02_RS17335	COG0022	dehydrogenase e1 component
A8C02_RS17340	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8C02_RS17345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8C02_RS17360	COG0625	glutathione transferase activity
A8C02_RS17365	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A8C02_RS17380	COG0579	oxidoreductase
A8C02_RS17385	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS17390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A8C02_RS17395	COG1113	amino acid transport
A8C02_RS17400	COG1802	Transcriptional regulator
A8C02_RS17420	COG2195	Cleaves the N-terminal amino acid of tripeptides
A8C02_RS17425	COG0454	-acetyltransferase
A8C02_RS17440	COG2991	Protein conserved in bacteria
A8C02_RS17455	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A8C02_RS17460	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A8C02_RS17480	COG3034	peptidoglycan biosynthetic process
A8C02_RS17485	COG0121	glutamine amidotransferase
A8C02_RS17495	COG1960	acyl-CoA dehydrogenase activity
A8C02_RS17500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A8C02_RS17510	COG0583	DNA-binding transcription factor activity
A8C02_RS17520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A8C02_RS17530	COG2226	methyltransferase
A8C02_RS17540	COG0741	lytic transglycosylase activity
A8C02_RS17540	COG1388	LysM domain
A8C02_RS17545	COG2226	methyltransferase
A8C02_RS17555	COG2814	Major facilitator Superfamily
A8C02_RS17560	COG0583	DNA-binding transcription factor activity
A8C02_RS17565	COG0656	L-ascorbic acid biosynthetic process
A8C02_RS17600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A8C02_RS17610	COG2011	ABC-type metal ion transport system permease component
A8C02_RS17615	COG1464	Belongs to the NlpA lipoprotein family
A8C02_RS17625	COG1720	tRNA m6t6A37 methyltransferase activity
A8C02_RS17635	COG0791	NLP P60 protein
A8C02_RS17640	COG3015	lipoprotein NlpE involved in copper resistance
A8C02_RS17645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A8C02_RS17660	COG4568	rho-dependent transcription termination
A8C02_RS17670	COG0346	lactoylglutathione lyase activity
A8C02_RS17675	COG1982	Orn Lys Arg decarboxylase major
A8C02_RS17685	COG0587	DNA-directed DNA polymerase activity
A8C02_RS17715	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
A8C02_RS17725	COG0750	zinc metalloprotease
A8C02_RS17730	COG0575	Belongs to the CDS family
A8C02_RS17740	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A8C02_RS17765	COG0024	Methionine aminopeptidase
A8C02_RS17770	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
A8C02_RS17785	COG3835	regulator
A8C02_RS17790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8C02_RS17810	COG2860	membrane
A8C02_RS17830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A8C02_RS17835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A8C02_RS17840	COG1120	ATPase activity
A8C02_RS17850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A8C02_RS17950	COG1643	Atp-dependent helicase
A8C02_RS17955	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A8C02_RS17975	COG0617	tRNA 3'-terminal CCA addition
A8C02_RS17980	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A8C02_RS18000	COG0726	polysaccharide deacetylase
A8C02_RS18005	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C02_RS18010	COG0842	Transport permease protein
A8C02_RS18015	COG1131	(ABC) transporter
A8C02_RS18020	COG0288	reversible hydration of carbon dioxide
A8C02_RS18035	COG4993	Dehydrogenase
A8C02_RS18040	COG2132	Multicopper oxidase
A8C02_RS18085	COG3064	Membrane
A8C02_RS18100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8C02_RS18105	COG0508	dehydrogenase complex catalyzes the overall conversion of
A8C02_RS18110	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A8C02_RS18115	COG2186	Transcriptional regulator
A8C02_RS18125	COG1113	amino acid transport
A8C02_RS18130	COG2211	Major facilitator Superfamily
A8C02_RS18135	COG3940	Belongs to the glycosyl hydrolase 43 family
A8C02_RS18140	COG3725	Membrane protein required for beta-lactamase induction
A8C02_RS18145	COG3023	N-Acetylmuramoyl-L-alanine amidase
A8C02_RS18155	COG4969	Belongs to the N-Me-Phe pilin family
A8C02_RS18160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A8C02_RS18165	COG1459	type II secretion system
A8C02_RS18195	COG0494	nUDIX hydrolase
A8C02_RS18215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A8C02_RS18220	COG0849	cell division
A8C02_RS18245	COG0772	Belongs to the SEDS family
A8C02_RS18260	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A8C02_RS18265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A8C02_RS18270	COG0768	penicillin binding
A8C02_RS18290	COG1609	Transcriptional regulator
A8C02_RS18300	COG0028	Belongs to the TPP enzyme family
A8C02_RS18345	COG0738	Major facilitator superfamily
A8C02_RS18355	COG0583	DNA-binding transcription factor activity
A8C02_RS18360	COG2271	Major facilitator Superfamily
A8C02_RS18365	COG2814	Major facilitator Superfamily
A8C02_RS18390	COG1178	ABC-type Fe3 transport system permease component
A8C02_RS18400	COG0586	Pfam SNARE associated Golgi protein
A8C02_RS18425	COG0235	Class ii aldolase
A8C02_RS18430	COG0417	DNA replication proofreading
A8C02_RS18440	COG0564	pseudouridine synthase activity
A8C02_RS18455	COG3493	citrate carrier protein
A8C02_RS18470	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A8C02_RS18475	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A8C02_RS18485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A8C02_RS18530	COG0505	Belongs to the CarA family
A8C02_RS18550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A8C02_RS18575	COG1047	Peptidyl-prolyl cis-trans
A8C02_RS18590	COG0196	riboflavin kinase activity
A8C02_RS18605	COG0583	DNA-binding transcription factor activity
A8C02_RS18630	COG4735	regulation of single-species biofilm formation
A8C02_RS18670	COG1584	GPR1 FUN34 yaaH family protein
A8C02_RS18675	COG0477	Major facilitator Superfamily
A8C02_RS18680	COG0521	Mo-molybdopterin cofactor biosynthetic process
A8C02_RS18685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A8C02_RS18690	COG1115	amino acid carrier protein
A8C02_RS18705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A8C02_RS18715	COG0460	homoserine dehydrogenase
A8C02_RS18715	COG0527	aspartate kinase activity
A8C02_RS18725	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A8C02_RS18730	COG0745	RESPONSE REGULATOR receiver
A8C02_RS18735	COG4452	Inner membrane protein CreD
A8C02_RS18740	COG2205	protein histidine kinase activity
A8C02_RS18745	COG0745	RESPONSE REGULATOR receiver
A8C02_RS18750	COG3045	CreA protein
A8C02_RS18755	COG2207	Transcriptional regulator
A8C02_RS18755	COG3708	Transcriptional regulator
A8C02_RS18775	COG0741	lytic transglycosylase activity
A8C02_RS18780	COG0488	(ABC) transporter
A8C02_RS18790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A8C02_RS18795	COG0560	Phosphoserine phosphatase
A8C02_RS18800	COG3726	membrane protein affecting hemolysin expression
A8C02_RS18830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A8C02_RS18835	COG0084	hydrolase, TatD family'
A8C02_RS18840	COG4667	esterase of the alpha-beta hydrolase superfamily
A8C02_RS18850	COG2823	Periplasmic or secreted lipoprotein
A8C02_RS18860	COG1011	Hydrolase
A8C02_RS18865	COG0456	acetyltransferase
A8C02_RS18870	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
A8C02_RS18920	COG4114	ferric iron reductase
A8C02_RS18925	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C02_RS18925	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C02_RS18930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A8C02_RS18935	COG2197	response regulator
A8C02_RS18940	COG2197	response regulator
A8C02_RS18960	COG2966	Psort location CytoplasmicMembrane, score
A8C02_RS18975	COG1484	DNA-dependent DNA replication
A8C02_RS18990	COG5464	transposase or invertase
A8C02_RS19000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A8C02_RS19005	COG3716	PTS system mannose fructose sorbose family IID component
A8C02_RS19010	COG3715	PTS system
A8C02_RS19025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A8C02_RS19025	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A8C02_RS19035	COG1063	alcohol dehydrogenase
A8C02_RS19040	COG1802	Transcriptional regulator
A8C02_RS19045	COG2271	Major facilitator Superfamily
A8C02_RS19050	COG0456	acetyltransferase
A8C02_RS19050	COG1214	PFAM Peptidase M22, glycoprotease
A8C02_RS19060	COG1737	Transcriptional regulator
A8C02_RS19065	COG0800	Aldolase
A8C02_RS19070	COG3734	2-keto-3-deoxy-galactonokinase
A8C02_RS19085	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
A8C02_RS19115	COG1846	Transcriptional regulator
A8C02_RS19125	COG0179	Fumarylacetoacetate (FAA) hydrolase
A8C02_RS19135	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS19140	COG3384	dioxygenase
A8C02_RS19150	COG3971	2-oxopent-4-enoate hydratase activity
A8C02_RS19170	COG2368	4-hydroxyphenylacetate
A8C02_RS19175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A8C02_RS19190	COG1966	Carbon starvation protein
A8C02_RS19195	COG2879	small protein
A8C02_RS19200	COG0523	cobalamin synthesis protein
A8C02_RS19210	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS19215	COG5464	transposase or invertase
A8C02_RS19220	COG1917	Cupin 2, conserved barrel domain protein
A8C02_RS19220	COG2207	Transcriptional regulator
A8C02_RS19230	COG2733	membrane
A8C02_RS19245	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
A8C02_RS19250	COG1924	4 iron, 4 sulfur cluster binding
A8C02_RS19265	COG1566	PFAM secretion protein HlyD family protein
A8C02_RS19275	COG5457	Domain of unknown function (DUF1127)
A8C02_RS19280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C02_RS19305	COG0583	DNA-binding transcription factor activity
A8C02_RS19310	COG2249	NAD(P)H dehydrogenase (quinone) activity
A8C02_RS19320	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS19325	COG1129	ABC transporter
A8C02_RS19330	COG1879	ABC-type sugar transport system periplasmic component
A8C02_RS19340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C02_RS19345	COG1129	ABC transporter
A8C02_RS19345	COG0842	Transport permease protein
A8C02_RS19350	COG0842	Transport permease protein
A8C02_RS19385	COG2850	peptidyl-arginine hydroxylation
A8C02_RS19400	COG5002	protein histidine kinase activity
A8C02_RS19405	COG0745	RESPONSE REGULATOR receiver
A8C02_RS19415	COG1538	Outer membrane efflux protein
A8C02_RS19420	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C02_RS19425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C02_RS19430	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8C02_RS19440	COG3040	lipid binding
A8C02_RS19445	COG0789	Transcriptional regulator
A8C02_RS19450	COG3631	Ketosteroid isomerase-related protein
A8C02_RS19455	COG0300	oxidoreductase activity
A8C02_RS19470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A8C02_RS19490	COG3272	Protein of unknown function (DUF1722)
A8C02_RS19500	COG4580	involved in the transport of maltose and maltodextrins
A8C02_RS19515	COG0582	viral genome integration into host DNA
A8C02_RS19525	COG0288	reversible hydration of carbon dioxide
A8C02_RS19530	COG0659	secondary active sulfate transmembrane transporter activity
A8C02_RS19535	COG1064	alcohol dehydrogenase
A8C02_RS19540	COG1175	transmembrane transport
A8C02_RS19545	COG0395	ABC-type sugar transport system, permease component
A8C02_RS19550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A8C02_RS19555	COG3842	ATPase activity
A8C02_RS19570	COG1082	Xylose isomerase domain protein TIM barrel
A8C02_RS19580	COG3962	Belongs to the TPP enzyme family
A8C02_RS19590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C02_RS19595	COG1737	Transcriptional regulator
A8C02_RS19595	COG0837	glucose binding
A8C02_RS19605	COG3718	enzyme involved in inositol metabolism
A8C02_RS19620	COG0433	COG0433 Predicted ATPase
A8C02_RS19625	COG0795	lipopolysaccharide-transporting ATPase activity
A8C02_RS19630	COG0795	lipopolysaccharide-transporting ATPase activity
A8C02_RS19640	COG2927	DNA polymerase III (CHI subunit)
A8C02_RS19645	COG0525	valine-tRNA ligase activity
A8C02_RS19670	COG2731	YhcH YjgK YiaL family protein
A8C02_RS19700	COG1263	PTS System
A8C02_RS19700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C02_RS19705	COG0366	Alpha amylase catalytic
A8C02_RS19710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C02_RS19715	COG1486	melibiose metabolic process
A8C02_RS19745	COG0602	queuosine metabolic process
A8C02_RS19750	COG2026	Addiction module toxin, RelE StbE family
A8C02_RS19755	COG3077	Addiction module antitoxin, RelB DinJ family
A8C02_RS19760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C02_RS19760	COG3711	transcriptional antiterminator
A8C02_RS19765	COG2706	6-phosphogluconolactonase activity
A8C02_RS19780	COG3964	amidohydrolase
A8C02_RS19815	COG0312	modulator of DNA gyrase
A8C02_RS19840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A8C02_RS19850	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS19855	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS19870	COG1879	ABC-type sugar transport system periplasmic component
A8C02_RS19890	COG2105	PFAM AIG2 family protein
A8C02_RS19895	COG2911	Protein conserved in bacteria
A8C02_RS19900	COG0729	surface antigen
A8C02_RS19910	COG1253	flavin adenine dinucleotide binding
A8C02_RS19935	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A8C02_RS19950	COG1733	regulation of RNA biosynthetic process
A8C02_RS19955	COG0702	epimerase
A8C02_RS19965	COG0697	spore germination
A8C02_RS19975	COG1113	amino acid transport
A8C02_RS19980	COG0545	Peptidyl-prolyl cis-trans isomerase
A8C02_RS19985	COG3061	Opacity-associated protein A
A8C02_RS19995	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A8C02_RS20000	COG2965	DNA replication, synthesis of RNA primer
A8C02_RS20060	COG1073	alpha beta
A8C02_RS20065	COG3650	response to hydrogen peroxide
A8C02_RS20075	COG1960	acyl-CoA dehydrogenase activity
A8C02_RS20080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8C02_RS20085	COG0557	exoribonuclease II activity
A8C02_RS20100	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
A8C02_RS20115	COG0330	HflC and HflK could
A8C02_RS20120	COG0330	HflC and HflK could
A8C02_RS20125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A8C02_RS20145	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8C02_RS20150	COG0802	atpase or kinase
A8C02_RS20155	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A8C02_RS20155	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A8C02_RS20160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A8C02_RS20185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C02_RS20205	COG3264	Mechanosensitive ion channel
A8C02_RS20205	COG1511	domain protein
A8C02_RS20220	COG1053	succinate dehydrogenase
A8C02_RS20225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A8C02_RS20245	COG2076	Multidrug Resistance protein
A8C02_RS20250	COG5510	response to toxic substance
A8C02_RS20265	COG1509	lysine 2,3-aminomutase activity
A8C02_RS20285	COG2963	transposase activity
A8C02_RS20290	COG3344	reverse transcriptase
A8C02_RS20295	COG2801	Transposase and inactivated derivatives
A8C02_RS20310	COG3188	usher protein
A8C02_RS20315	COG3539	Fimbrial protein
A8C02_RS20345	COG0531	amino acid
A8C02_RS20350	COG3030	protein affecting phage T7 exclusion by the F plasmid
A8C02_RS20360	COG1027	Aspartate ammonia-lyase
A8C02_RS20365	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A8C02_RS20380	COG1309	transcriptional regulator
A8C02_RS20415	COG0457	Tetratricopeptide repeat
A8C02_RS20420	COG0726	polysaccharide deacetylase
A8C02_RS20420	COG1649	PFAM Uncharacterised BCR, COG1649
A8C02_RS20425	COG1215	transferase activity, transferring glycosyl groups
A8C02_RS20445	COG0861	Integral membrane protein TerC family
A8C02_RS20485	COG1486	melibiose metabolic process
A8C02_RS20490	COG2169	Transcriptional regulator
A8C02_RS20505	COG2824	Alkylphosphonate utilization operon protein PhnA
A8C02_RS20510	COG2764	glyoxalase bleomycin resistance protein dioxygenase
A8C02_RS20515	COG2188	Transcriptional regulator
A8C02_RS20520	COG3624	Phosphonate C-P lyase system protein PhnG
A8C02_RS20525	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
A8C02_RS20530	COG3626	phosphonate metabolism
A8C02_RS20535	COG3627	carbon phosphorus lyase activity
A8C02_RS20540	COG4107	phosphonate C-P lyase system protein PhnK
A8C02_RS20545	COG4778	phosphonate C-P lyase system protein PhnL
A8C02_RS20550	COG3454	Phosphonate metabolism
A8C02_RS20560	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A8C02_RS20570	COG0784	Response regulator, receiver
A8C02_RS20570	COG4191	Histidine kinase
A8C02_RS20580	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS20615	COG3383	formate dehydrogenase (NAD+) activity
A8C02_RS20620	COG3383	formate dehydrogenase (NAD+) activity
A8C02_RS20625	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
A8C02_RS20630	COG1301	dicarboxylic acid transport
A8C02_RS20640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A8C02_RS20650	COG3162	membrane
A8C02_RS20680	COG3539	Fimbrial protein
A8C02_RS20690	COG1346	cytolysis
A8C02_RS20695	COG1380	Effector of murein hydrolase LrgA
A8C02_RS20700	COG0583	DNA-binding transcription factor activity
A8C02_RS20705	COG0025	NhaP-type Na H and K H
A8C02_RS20710	COG2252	PERMEase
A8C02_RS20715	COG0625	glutathione transferase activity
A8C02_RS20720	COG0789	Transcriptional regulator
A8C02_RS20730	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A8C02_RS20760	COG1234	tRNA 3'-trailer cleavage
A8C02_RS20765	COG1609	Transcriptional regulator
A8C02_RS20770	COG0483	inositol monophosphate 1-phosphatase activity
A8C02_RS20780	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A8C02_RS20805	COG4771	TonB-dependent receptor
A8C02_RS20815	COG0741	lytic transglycosylase activity
A8C02_RS20830	COG2315	Protein conserved in bacteria
A8C02_RS20835	COG0432	Pfam Uncharacterised protein family UPF0047
A8C02_RS20850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A8C02_RS20855	COG0305	Participates in initiation and elongation during chromosome replication
A8C02_RS20870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A8C02_RS20885	COG0735	belongs to the Fur family
A8C02_RS20890	COG3237	CsbD-like
A8C02_RS20900	COG0534	Mate efflux family protein
A8C02_RS20910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A8C02_RS20980	COG0251	oxidation-reduction process
A8C02_RS20990	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A8C02_RS21000	COG0527	aspartate kinase activity
A8C02_RS21050	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A8C02_RS21060	COG0456	acetyltransferase
A8C02_RS21095	COG0151	Belongs to the GarS family
A8C02_RS21105	COG4191	Histidine kinase
A8C02_RS21115	COG3678	ATP-independent chaperone mediated protein folding
A8C02_RS21150	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
A8C02_RS21165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A8C02_RS21170	COG2104	thiamine diphosphate biosynthetic process
A8C02_RS21190	COG3706	GGDEF domain
A8C02_RS21200	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8C02_RS21205	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A8C02_RS21240	COG0250	Participates in transcription elongation, termination and antitermination
A8C02_RS21285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A8C02_RS21315	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
A8C02_RS21325	COG1739	Uncharacterized protein family UPF0029
A8C02_RS21370	COG0805	protein transport
A8C02_RS21390	COG3165	ubiquinone biosynthetic process from chorismate
A8C02_RS21420	COG0583	DNA-binding transcription factor activity
A8C02_RS21425	COG0697	spore germination
A8C02_RS21430	COG0561	phosphatase activity
A8C02_RS21435	COG2267	carboxylic ester hydrolase activity
A8C02_RS21440	COG1280	lysine exporter protein (LysE YggA)
A8C02_RS21450	COG1280	lysine exporter protein (LysE YggA)
A8C02_RS21485	COG0210	DNA helicase
A8C02_RS21490	COG1011	Hydrolase
A8C02_RS21520	COG3072	Adenylate cyclase
A8C02_RS21540	COG2959	enzyme of heme biosynthesis
A8C02_RS21545	COG3071	HemY protein
A8C02_RS21595	COG2244	polysaccharide biosynthetic process
A8C02_RS21600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A8C02_RS21605	COG0456	acetyltransferase
A8C02_RS21610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A8C02_RS21615	COG1088	dTDP-glucose 4,6-dehydratase activity
A8C02_RS21620	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A8C02_RS21625	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A8C02_RS21635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A8C02_RS21640	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A8C02_RS21645	COG3118	belongs to the thioredoxin family
A8C02_RS21670	COG1811	Na channel or pump
A8C02_RS21680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8C02_RS21685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A8C02_RS21695	COG0583	DNA-binding transcription factor activity
A8C02_RS21700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A8C02_RS21715	COG3978	acetolactate synthase activity
A8C02_RS21735	COG3085	chromosome segregation
A8C02_RS21810	COG0583	DNA-binding transcription factor activity
A8C02_RS21825	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A8C02_RS21840	COG3443	Belongs to the bacterial solute-binding protein 9 family
A8C02_RS21845	COG2207	Transcriptional regulator
A8C02_RS21855	COG0371	Dehydrogenase
A8C02_RS21860	COG0697	spore germination
A8C02_RS21870	COG0583	DNA-binding transcription factor activity
A8C02_RS21880	COG0737	Belongs to the 5'-nucleotidase family
A8C02_RS21890	COG0460	homoserine dehydrogenase
A8C02_RS21890	COG0527	aspartate kinase activity
A8C02_RS21895	COG0626	cystathionine gamma-synthase activity
A8C02_RS21910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A8C02_RS21920	COG1609	Transcriptional regulator
A8C02_RS21925	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A8C02_RS21940	COG1575	Belongs to the MenA family. Type 1 subfamily
A8C02_RS21960	COG3678	ATP-independent chaperone mediated protein folding
A8C02_RS21965	COG0745	RESPONSE REGULATOR receiver
A8C02_RS21970	COG2205	protein histidine kinase activity
A8C02_RS21975	COG2258	MOSC domain
A8C02_RS21980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A8C02_RS22020	COG1129	ABC transporter
A8C02_RS22025	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS22030	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS22035	COG1454	alcohol dehydrogenase
A8C02_RS22045	COG2211	Major facilitator Superfamily
A8C02_RS22135	COG0243	molybdopterin cofactor binding
A8C02_RS22135	COG3383	formate dehydrogenase (NAD+) activity
A8C02_RS22140	COG0243	molybdopterin cofactor binding
A8C02_RS22140	COG3383	formate dehydrogenase (NAD+) activity
A8C02_RS22145	COG0437	4 iron, 4 sulfur cluster binding
A8C02_RS22150	COG2864	formate dehydrogenase
A8C02_RS22165	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A8C02_RS22175	COG0456	acetyltransferase
A8C02_RS22190	COG1011	Hydrolase
A8C02_RS22210	COG3852	Histidine kinase
A8C02_RS22220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A8C02_RS22240	COG0204	Acyl-transferase
A8C02_RS22250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A8C02_RS22255	COG3084	Protein conserved in bacteria
A8C02_RS22265	COG1763	Mo-molybdopterin cofactor biosynthetic process
A8C02_RS22290	COG2186	Transcriptional regulator
A8C02_RS22295	COG0477	Major facilitator Superfamily
A8C02_RS22300	COG1609	Transcriptional regulator
A8C02_RS22305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C02_RS22315	COG1172	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS22320	COG1129	ABC transporter
A8C02_RS22350	COG1522	sequence-specific DNA binding
A8C02_RS22355	COG0716	FMN binding
A8C02_RS22370	COG3312	ion transport
A8C02_RS22435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A8C02_RS22440	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A8C02_RS22445	COG0573	inorganic phosphate transmembrane transporter activity
A8C02_RS22450	COG0581	inorganic phosphate transmembrane transporter activity
A8C02_RS22455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A8C02_RS22460	COG0704	Plays a role in the regulation of phosphate uptake
A8C02_RS22475	COG2382	esterase
A8C02_RS22480	COG0363	glucosamine-6-phosphate deaminase activity
A8C02_RS22485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A8C02_RS22495	COG2252	PERMEase
A8C02_RS22500	COG0431	NADPH-dependent FMN reductase
A8C02_RS22505	COG2091	lysine biosynthetic process via aminoadipic acid
A8C02_RS22535	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A8C02_RS22565	COG0187	DNA topoisomerase II activity
A8C02_RS22570	COG0561	phosphatase activity
A8C02_RS22585	COG2186	Transcriptional regulator
A8C02_RS22590	COG3734	2-keto-3-deoxy-galactonokinase
A8C02_RS22595	COG0800	Aldolase
A8C02_RS22605	COG2271	Major facilitator Superfamily
A8C02_RS22610	COG0823	Involved in the tonB-independent uptake of proteins
A8C02_RS22615	COG5645	(Lipo)protein
A8C02_RS22630	COG3645	SOS response
A8C02_RS22640	COG2188	Transcriptional regulator
A8C02_RS22655	COG2149	membrane
A8C02_RS22675	COG2610	gluconate transmembrane transporter activity
A8C02_RS22685	COG0583	DNA-binding transcription factor activity
A8C02_RS22690	COG2814	Major facilitator Superfamily
A8C02_RS22710	COG0028	Belongs to the TPP enzyme family
A8C02_RS22715	COG0440	acetolactate synthase activity
A8C02_RS22720	COG2197	response regulator
A8C02_RS22730	COG2271	Major facilitator Superfamily
A8C02_RS22780	COG2188	Transcriptional regulator
A8C02_RS22805	COG4580	involved in the transport of maltose and maltodextrins
A8C02_RS22810	COG1447	Phosphotransferase system cellobiose-specific component IIA
A8C02_RS22815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C02_RS22815	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C02_RS22825	COG1609	Transcriptional regulator
A8C02_RS22835	COG3384	dioxygenase
A8C02_RS22840	COG0583	DNA-binding transcription factor activity
A8C02_RS22845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A8C02_RS22850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A8C02_RS22855	COG2828	Protein conserved in bacteria
A8C02_RS22870	COG0697	spore germination
A8C02_RS22875	COG1263	PTS System
A8C02_RS22875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C02_RS22885	COG2814	Major facilitator Superfamily
A8C02_RS22895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8C02_RS22930	COG0583	DNA-binding transcription factor activity
A8C02_RS22955	COG1464	Belongs to the NlpA lipoprotein family
A8C02_RS22970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A8C02_RS22980	COG1064	alcohol dehydrogenase
A8C02_RS23010	COG2211	Major facilitator Superfamily
A8C02_RS23015	COG1501	Belongs to the glycosyl hydrolase 31 family
A8C02_RS23025	COG1486	melibiose metabolic process
A8C02_RS23030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A8C02_RS23030	COG1263	PTS System
A8C02_RS23035	COG2982	Protein involved in outer membrane biogenesis
A8C02_RS23040	COG2233	PERMEase
A8C02_RS23045	COG0786	glutamate:sodium symporter activity
A8C02_RS23060	COG3074	FtsZ-dependent cytokinesis
A8C02_RS23065	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A8C02_RS23090	COG3152	Membrane
A8C02_RS23100	COG1494	fructose-1,6-bisphosphatase
A8C02_RS23105	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A8C02_RS23110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A8C02_RS23115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A8C02_RS23135	COG2860	membrane
A8C02_RS23145	COG2169	Transcriptional regulator
A8C02_RS23145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A8C02_RS23150	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A8C02_RS23205	COG1561	YicC-like family, N-terminal region
A8C02_RS23225	COG1131	(ABC) transporter
A8C02_RS23235	COG0842	Transport permease protein
A8C02_RS23265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A8C02_RS23300	COG1519	Transferase
A8C02_RS23305	COG1216	Glycosyl transferase, family 2
A8C02_RS23310	COG0438	transferase activity, transferring glycosyl groups
A8C02_RS23320	COG0859	PFAM glycosyl transferase family 9
A8C02_RS23345	COG0859	PFAM glycosyl transferase family 9
A8C02_RS23360	COG0156	8-amino-7-oxononanoate synthase activity
A8C02_RS23370	COG0463	Glycosyl transferase, family 2
A8C02_RS23375	COG2861	carbohydrate metabolic process
A8C02_RS23380	COG4942	peptidase
A8C02_RS23390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A8C02_RS23395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A8C02_RS23415	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A8C02_RS23425	COG2186	Transcriptional regulator
A8C02_RS23445	COG3722	fumarate hydratase activity
A8C02_RS23465	COG1566	PFAM secretion protein HlyD family protein
A8C02_RS23470	COG0625	glutathione transferase activity
A8C02_RS23480	COG3276	selenocysteine insertion sequence binding
A8C02_RS23485	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A8C02_RS23490	COG3977	Valine--pyruvate aminotransferase
A8C02_RS23495	COG0366	Alpha amylase catalytic
A8C02_RS23500	COG2992	FlgJ-related protein
A8C02_RS23505	COG1609	Transcriptional regulator
A8C02_RS23505	COG2207	Transcriptional regulator
A8C02_RS23510	COG4214	carbohydrate transport
A8C02_RS23520	COG4213	ABC transporter substrate-binding protein
A8C02_RS23535	COG4682	membrane
A8C02_RS23540	COG4682	membrane
A8C02_RS23545	COG3274	enterobacterial common antigen metabolic process
A8C02_RS23575	COG1278	Cold shock
A8C02_RS23580	COG2944	sequence-specific DNA binding
A8C02_RS23585	COG2814	Major facilitator Superfamily
A8C02_RS23605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A8C02_RS23615	COG1609	Transcriptional regulator
A8C02_RS23625	COG2885	chlorophyll binding
A8C02_RS23630	COG0243	molybdopterin cofactor binding
A8C02_RS23635	COG0456	acetyltransferase
A8C02_RS23640	COG2818	Glycosylase
A8C02_RS23650	COG2223	nitrite transmembrane transporter activity
A8C02_RS23690	COG0747	negative chemotaxis
A8C02_RS23695	COG0601	transmembrane transport
A8C02_RS23700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C02_RS23705	COG0444	Belongs to the ABC transporter superfamily
A8C02_RS23710	COG4608	Belongs to the ABC transporter superfamily
A8C02_RS23725	COG2894	cell division
A8C02_RS23735	COG1215	transferase activity, transferring glycosyl groups
A8C02_RS23740	COG0457	Tetratricopeptide repeat
A8C02_RS23755	COG2194	sulfuric ester hydrolase activity
A8C02_RS23785	COG1215	transferase activity, transferring glycosyl groups
A8C02_RS23790	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A8C02_RS23795	COG0457	Tetratricopeptide repeat
A8C02_RS23795	COG3118	belongs to the thioredoxin family
A8C02_RS23805	COG2200	EAL domain
A8C02_RS23805	COG2199	diguanylate cyclase activity
A8C02_RS23815	COG0612	Peptidase, M16
A8C02_RS23830	COG2982	Protein involved in outer membrane biogenesis
A8C02_RS23835	COG0477	Major facilitator Superfamily
A8C02_RS23840	COG1295	ribonuclease BN
A8C02_RS23845	COG0583	DNA-binding transcription factor activity
A8C02_RS23850	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS23855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A8C02_RS23865	COG1454	alcohol dehydrogenase
A8C02_RS23875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A8C02_RS23880	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A8C02_RS23885	COG0671	phosphoesterase, PA-phosphatase related
A8C02_RS23905	COG0589	response to stress
A8C02_RS23915	COG0306	phosphate transporter
A8C02_RS23920	COG2081	HI0933 family
A8C02_RS23925	COG2239	Acts as a magnesium transporter
A8C02_RS23935	COG1124	(ABC) transporter
A8C02_RS23945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A8C02_RS23950	COG0601	transmembrane transport
A8C02_RS23955	COG0747	negative chemotaxis
A8C02_RS23965	COG3479	Phenolic acid decarboxylase
A8C02_RS24005	COG0628	permease
A8C02_RS24010	COG0477	Major facilitator Superfamily
A8C02_RS24020	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A8C02_RS24035	COG3714	YhhN family
A8C02_RS24045	COG3776	membrane
A8C02_RS24050	COG0742	ribosomal rna small subunit methyltransferase
A8C02_RS24055	COG0552	protein localization to endoplasmic reticulum
A8C02_RS24060	COG2884	Cell division ATP-binding protein ftsE
A8C02_RS24065	COG2177	Part of the ABC transporter FtsEX involved in
A8C02_RS24080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A8C02_RS24090	COG0683	leucine binding
A8C02_RS24105	COG0683	leucine binding
A8C02_RS24110	COG0559	Belongs to the binding-protein-dependent transport system permease family
A8C02_RS24160	COG0584	glycerophosphoryl diester phosphodiesterase
A8C02_RS24170	COG0405	Gamma-glutamyltransferase
A8C02_RS24175	COG1247	-acetyltransferase
A8C02_RS24185	COG0673	inositol 2-dehydrogenase activity
A8C02_RS24190	COG1741	Belongs to the pirin family
A8C02_RS24195	COG1609	Transcriptional regulator
A8C02_RS24200	COG3265	gluconokinase activity
A8C02_RS24205	COG2610	gluconate transmembrane transporter activity
A8C02_RS24215	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A8C02_RS24240	COG0058	SHG alpha-glucan phosphorylase activity
A8C02_RS24255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A8C02_RS24270	COG1349	DNA-binding transcription factor activity
A8C02_RS24280	COG0058	SHG alpha-glucan phosphorylase activity
A8C02_RS24285	COG1640	4-alpha-glucanotransferase
A8C02_RS24290	COG2610	gluconate transmembrane transporter activity
A8C02_RS24300	COG1040	competence protein
A8C02_RS24325	COG1918	ferrous iron import across plasma membrane
A8C02_RS24330	COG2183	response to ionizing radiation
A8C02_RS24335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A8C02_RS24365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A8C02_RS24370	COG1011	Hydrolase
A8C02_RS24380	COG0494	nUDIX hydrolase
A8C02_RS24385	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A8C02_RS24410	COG4796	Type ii and iii secretion system protein
A8C02_RS24425	COG3266	domain, Protein
A8C02_RS24430	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A8C02_RS24435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A8C02_RS24460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A8C02_RS24470	COG0402	S-adenosylhomocysteine deaminase activity
A8C02_RS24475	COG0738	Major facilitator superfamily
A8C02_RS24500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A8C02_RS24505	COG1289	transmembrane transporter activity
A8C02_RS24515	COG1765	OsmC-like protein
A8C02_RS24520	COG3954	Phosphoribulokinase
A8C02_RS24530	COG0429	hydrolase of the alpha beta-hydrolase fold
A8C02_RS24540	COG0488	(ABC) transporter
A8C02_RS24555	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
A8C02_RS24560	COG1047	Peptidyl-prolyl cis-trans
A8C02_RS24570	COG0545	Peptidyl-prolyl cis-trans isomerase
A8C02_RS24575	COG2964	Protein conserved in bacteria
A8C02_RS24630	COG0051	transcription antitermination factor activity, RNA binding
A8C02_RS24655	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A8C02_RS24670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A8C02_RS24735	COG0201	protein transport
A8C02_RS24755	COG0202	RNA polymerase activity
A8C02_RS24770	COG0789	Transcriptional regulator
A8C02_RS24810	COG0551	DNA topoisomerase type I activity
A8C02_RS24830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A8C02_RS24860	COG2963	transposase activity
A8C02_RS24865	COG2801	Transposase and inactivated derivatives
A8C02_RS24875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A8C02_RS24880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A8C02_RS24885	COG1309	transcriptional regulator
A8C02_RS24905	COG4145	pantothenate transmembrane transporter activity
A8C02_RS24910	COG3924	membrane
A8C02_RS24915	COG0439	Biotin carboxylase
A8C02_RS24920	COG0511	ligase activity, forming carbon-carbon bonds
A8C02_RS24945	COG2199	diguanylate cyclase activity
A8C02_RS24945	COG2200	EAL domain
A8C02_RS24950	COG1077	Cell shape determining protein MreB Mrl
A8C02_RS24955	COG1792	Involved in formation and maintenance of cell shape
A8C02_RS24960	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A8C02_RS24970	COG1530	ribonuclease E activity
A8C02_RS24975	COG3164	Protein of unknown function
A8C02_RS24980	COG0312	modulator of DNA gyrase
A8C02_RS24985	COG0583	DNA-binding transcription factor activity
A8C02_RS25000	COG1289	transmembrane transporter activity
A8C02_RS25005	COG2732	(Barnase) inhibitor
A8C02_RS25030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8C02_RS25035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A8C02_RS25040	COG3105	Protein conserved in bacteria
A8C02_RS25045	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A8C02_RS25060	COG0625	glutathione transferase activity
A8C02_RS25065	COG2969	positive regulation of protein catabolic process
A8C02_RS25075	COG0493	'glutamate synthase
A8C02_RS25080	COG0070	glutamate synthase
A8C02_RS25080	COG0069	glutamate synthase activity
A8C02_RS25080	COG0067	glutamate synthase
A8C02_RS25085	COG1242	4 iron, 4 sulfur cluster binding
A8C02_RS25090	COG2271	Major facilitator Superfamily
A8C02_RS25095	COG1063	alcohol dehydrogenase
A8C02_RS25105	COG1312	Catalyzes the dehydration of D-mannonate
A8C02_RS25110	COG0784	Response regulator, receiver
A8C02_RS25110	COG2198	Histidine kinase
A8C02_RS25110	COG5002	protein histidine kinase activity
A8C02_RS25115	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
A8C02_RS25120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A8C02_RS25125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C02_RS25135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A8C02_RS25140	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A8C02_RS25145	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A8C02_RS25150	COG1137	ATPase activity
A8C02_RS25155	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A8C02_RS25160	COG3117	lipopolysaccharide transmembrane transporter activity
A8C02_RS25165	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A8C02_RS25175	COG0530	calcium, potassium:sodium antiporter activity
A8C02_RS25180	COG1127	ABC transporter
A8C02_RS25185	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A8C02_RS25190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A8C02_RS25195	COG2854	intermembrane phospholipid transfer
A8C02_RS25200	COG3113	response to antibiotic
A8C02_RS25205	COG5007	Belongs to the BolA IbaG family
A8C02_RS25215	COG3423	Transcriptional regulator
A8C02_RS25220	COG0142	geranyltranstransferase activity
A8C02_RS25235	COG0697	spore germination
A8C02_RS25245	COG2027	D-alanyl-D-alanine carboxypeptidase
A8C02_RS25255	COG1534	Rna-binding protein
A8C02_RS25265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A8C02_RS25270	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A8C02_RS25280	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A8C02_RS25325	COG0195	Participates in both transcription termination and antitermination
A8C02_RS25370	COG0814	amino acid
A8C02_RS25395	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A8C02_RS25440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C02_RS25445	COG0826	peptidase U32
A8C02_RS25450	COG0826	peptidase U32
A8C02_RS25455	COG3154	lipid carrier protein
A8C02_RS25460	COG3153	acetyltransferase
A8C02_RS25475	COG0693	protein deglycase activity
A8C02_RS25480	COG0702	epimerase
A8C02_RS25485	COG0701	Predicted permease
A8C02_RS25490	COG2823	Periplasmic or secreted lipoprotein
A8C02_RS25510	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A8C02_RS25515	COG2721	sulfolactate sulfo-lyase activity
A8C02_RS25525	COG2271	Major facilitator Superfamily
A8C02_RS25535	COG2084	Dehydrogenase
A8C02_RS25540	COG1929	Belongs to the glycerate kinase type-1 family
A8C02_RS25570	COG1741	Belongs to the pirin family
A8C02_RS25575	COG0583	DNA-binding transcription factor activity
A8C02_RS25580	COG3152	Membrane
A8C02_RS25585	COG0435	Glutathione S-transferase
A8C02_RS25590	COG2259	Doxx family
A8C02_RS25600	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
A8C02_RS25605	COG4575	ribosome binding
A8C02_RS25610	COG1422	Protein of unknown function (DUF1090)
A8C02_RS25620	COG0586	Pfam SNARE associated Golgi protein
A8C02_RS25625	COG2186	Transcriptional regulator
A8C02_RS25630	COG2271	Major facilitator Superfamily
A8C02_RS25640	COG2721	sulfolactate sulfo-lyase activity
A8C02_RS25655	COG0861	Integral membrane protein TerC family
A8C02_RS25660	COG0673	inositol 2-dehydrogenase activity
A8C02_RS25665	COG1451	nucleotide metabolic process
A8C02_RS25685	COG0446	pyridine nucleotide-disulphide oxidoreductase
A8C02_RS25685	COG1902	pentaerythritol trinitrate reductase activity
A8C02_RS25735	COG1695	Transcriptional regulator
A8C02_RS25745	COG2375	cellular response to nickel ion
A8C02_RS25760	COG1461	Dihydroxyacetone kinase
A8C02_RS25765	COG2376	Dihydroxyacetone kinase
A8C02_RS25835	COG3039	Transposase
A8C02_RS25845	COG2198	Histidine kinase
A8C02_RS25845	COG2205	protein histidine kinase activity
A8C02_RS25845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A8C02_RS25845	COG0784	Response regulator, receiver
A8C02_RS25850	COG2197	response regulator
A8C02_RS25880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A8C02_RS25885	COG0358	DNA primase activity
A8C02_RS25890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A8C02_RS25975	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A8C02_RS25990	COG4991	sh3 domain protein
A8C02_RS25995	COG3025	triphosphatase activity
A8C02_RS26020	COG2960	long-chain fatty acid transporting porin activity
A8C02_RS26035	COG3384	dioxygenase
A8C02_RS26040	COG0754	glutathionylspermidine amidase activity
A8C02_RS26050	COG1538	Outer membrane efflux protein
A8C02_RS26055	COG0494	nUDIX hydrolase
A8C02_RS26060	COG3151	Protein conserved in bacteria
A8C02_RS26065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A8C02_RS26070	COG3150	esterase
A8C02_RS26080	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A8C02_RS26085	COG2249	NAD(P)H dehydrogenase (quinone) activity
A8C02_RS26090	COG0642	Histidine kinase
A8C02_RS26100	COG3111	PFAM Bacterial OB fold (BOF) protein
A8C02_RS26105	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
A8C02_RS26115	COG0204	Acyl-transferase
A8C02_RS26120	COG2132	Multicopper oxidase
A8C02_RS26125	COG1032	radical SAM domain protein
A8C02_RS26130	COG0656	L-ascorbic acid biosynthetic process
A8C02_RS26135	COG1979	alcohol dehydrogenase
A8C02_RS26140	COG2207	Transcriptional regulator
A8C02_RS26145	COG0586	Pfam SNARE associated Golgi protein
A8C02_RS26150	COG0626	cystathionine gamma-synthase activity
A8C02_RS26165	COG0848	biopolymer transport protein
A8C02_RS26180	COG0625	glutathione transferase activity
A8C02_RS26195	COG0754	glutathionylspermidine amidase activity
A8C02_RS26200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A8C02_RS26220	COG0583	DNA-binding transcription factor activity
A8C02_RS26225	COG0626	cystathionine gamma-synthase activity
A8C02_RS26240	COG1811	Na channel or pump
A8C02_RS26245	COG1982	Orn Lys Arg decarboxylase major
A8C02_RS26250	COG2211	Major facilitator Superfamily
A8C02_RS26265	COG1194	a g-specific adenine glycosylase
A8C02_RS26275	COG3171	Protein conserved in bacteria
A8C02_RS26295	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A8C02_RS26295	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A8C02_RS26300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A8C02_RS26305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A8C02_RS26320	COG0762	integral membrane protein
A8C02_RS26325	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A8C02_RS26330	COG2805	Type II/IV secretion system protein
A8C02_RS26355	COG0189	ligase activity
A8C02_RS26360	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A8C02_RS26365	COG2356	endonuclease I
A8C02_RS26375	COG2814	Major facilitator Superfamily
A8C02_RS26405	COG0501	Belongs to the peptidase M48B family
A8C02_RS26410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A8C02_RS26425	COG0191	fructose-bisphosphate aldolase activity
A8C02_RS26430	COG0668	transmembrane transport
A8C02_RS26445	COG2968	Membrane
A8C02_RS26465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A8C02_RS26470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A8C02_RS26490	COG0006	proline dipeptidase activity
A8C02_RS26495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8C02_RS26500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A8C02_RS26520	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS26525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A8C02_RS26545	COG2723	6-phospho-beta-galactosidase activity
A8C02_RS26550	COG1737	Transcriptional regulator
A8C02_RS26560	COG1272	protein, Hemolysin III
A8C02_RS26570	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
A8C02_RS26580	COG0716	FMN binding
A8C02_RS26585	COG4974	Belongs to the 'phage' integrase family
A8C02_RS26595	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A8C02_RS26615	COG4942	peptidase
A8C02_RS26625	COG2814	Major facilitator Superfamily
A8C02_RS26640	COG0667	Aldo Keto reductase
A8C02_RS26680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A8C02_RS26685	COG1393	Belongs to the ArsC family
A8C02_RS26705	COG1538	Outer membrane efflux protein
A8C02_RS26710	COG1289	transmembrane transporter activity
A8C02_RS26725	COG3592	Divergent 4Fe-4S mono-cluster
A8C02_RS26730	COG2388	GCN5-related N-acetyl-transferase
A8C02_RS26735	COG3539	Fimbrial protein
A8C02_RS26740	COG3539	Fimbrial protein
A8C02_RS26745	COG3539	Fimbrial protein
A8C02_RS26750	COG3188	usher protein
A8C02_RS26755	COG3121	Chaperone
A8C02_RS26760	COG3539	Fimbrial protein
A8C02_RS26775	COG4974	Belongs to the 'phage' integrase family
A8C02_RS26780	COG0582	viral genome integration into host DNA
A8C02_RS26795	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
A8C02_RS26800	COG1846	Transcriptional regulator
A8C02_RS26805	COG0697	spore germination
A8C02_RS26855	COG0667	Aldo Keto reductase
A8C02_RS26860	COG0814	amino acid
A8C02_RS26875	COG0183	Belongs to the thiolase family
A8C02_RS26885	COG0823	Involved in the tonB-independent uptake of proteins
A8C02_RS26890	COG1028	Short-chain dehydrogenase reductase Sdr
A8C02_RS26895	COG2814	Major facilitator Superfamily
A8C02_RS26930	COG3842	ATPase activity
A8C02_RS26935	COG0395	ABC-type sugar transport system, permease component
A8C02_RS26940	COG1175	transmembrane transport
A8C02_RS26950	COG1917	Cupin 2, conserved barrel domain protein
A8C02_RS26955	COG1794	racemase activity, acting on amino acids and derivatives
A8C02_RS26960	COG0583	DNA-binding transcription factor activity
A8C02_RS26970	COG1609	Transcriptional regulator
A8C02_RS26975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A8C02_RS26980	COG2723	6-phospho-beta-galactosidase activity
A8C02_RS26985	COG2186	Transcriptional regulator
A8C02_RS26995	COG1609	Transcriptional regulator
A8C02_RS27015	COG0667	Aldo Keto reductase
A8C02_RS27025	COG0861	Integral membrane protein TerC family
A8C02_RS27060	COG2165	general secretion pathway protein
A8C02_RS27065	COG4795	General secretion pathway protein
A8C02_RS27075	COG4967	type IV pilus modification protein PilV
A8C02_RS27080	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A8C02_RS27085	COG1025	Belongs to the peptidase M16 family
A8C02_RS27090	COG1074	ATP-dependent DNA helicase activity
A8C02_RS27095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A8C02_RS27100	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A8C02_RS27100	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A8C02_RS27105	COG0860	N-Acetylmuramoyl-L-alanine amidase
A8C02_RS27110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A8C02_RS27140	COG4656	Part of a membrane complex involved in electron transport
A8C02_RS27145	COG1012	belongs to the aldehyde dehydrogenase family
A8C02_RS27145	COG1454	alcohol dehydrogenase
A8C02_RS27160	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
A8C02_RS27175	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
A8C02_RS27340	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A8C02_RS27345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A8C02_RS27350	COG2166	iron-sulfur cluster assembly
A8C02_RS27355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A8C02_RS27365	COG0583	DNA-binding transcription factor activity
A8C02_RS27370	COG2363	Small membrane protein
A8C02_RS27380	COG1349	DNA-binding transcription factor activity
A8C02_RS27400	COG0738	Major facilitator superfamily
A8C02_RS27410	COG0235	Class ii aldolase
A8C02_RS27415	COG1454	alcohol dehydrogenase
A8C02_RS27435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A8C02_RS27450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A8C02_RS27455	COG2011	ABC-type metal ion transport system permease component
A8C02_RS27460	COG1464	Belongs to the NlpA lipoprotein family
A8C02_RS27505	COG1660	Displays ATPase and GTPase activities
A8C02_RS27765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance