locus-tag	class	description
BCV49_RS00005	COG0716	FMN binding
BCV49_RS00010	COG1522	sequence-specific DNA binding
BCV49_RS00040	COG1129	ABC transporter
BCV49_RS00045	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS00055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV49_RS00060	COG1609	Transcriptional regulator
BCV49_RS00065	COG0477	Major facilitator Superfamily
BCV49_RS00070	COG2186	Transcriptional regulator
BCV49_RS00095	COG1763	Mo-molybdopterin cofactor biosynthetic process
BCV49_RS00105	COG3084	Protein conserved in bacteria
BCV49_RS00110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCV49_RS00120	COG0204	Acyl-transferase
BCV49_RS00140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCV49_RS00150	COG3852	Histidine kinase
BCV49_RS00170	COG1011	Hydrolase
BCV49_RS00185	COG0456	acetyltransferase
BCV49_RS00195	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BCV49_RS00210	COG2864	formate dehydrogenase
BCV49_RS00215	COG0437	4 iron, 4 sulfur cluster binding
BCV49_RS00220	COG0243	molybdopterin cofactor binding
BCV49_RS00220	COG3383	formate dehydrogenase (NAD+) activity
BCV49_RS00225	COG3383	formate dehydrogenase (NAD+) activity
BCV49_RS00225	COG0243	molybdopterin cofactor binding
BCV49_RS00240	COG0205	6-phosphofructokinase activity
BCV49_RS00300	COG2211	Major facilitator Superfamily
BCV49_RS00310	COG1454	alcohol dehydrogenase
BCV49_RS00315	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS00320	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS00325	COG1129	ABC transporter
BCV49_RS00365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCV49_RS00370	COG2258	MOSC domain
BCV49_RS00375	COG2205	protein histidine kinase activity
BCV49_RS00380	COG0745	RESPONSE REGULATOR receiver
BCV49_RS00385	COG3678	ATP-independent chaperone mediated protein folding
BCV49_RS00405	COG1575	Belongs to the MenA family. Type 1 subfamily
BCV49_RS00420	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BCV49_RS00425	COG1609	Transcriptional regulator
BCV49_RS00435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCV49_RS00450	COG0626	cystathionine gamma-synthase activity
BCV49_RS00455	COG0527	aspartate kinase activity
BCV49_RS00455	COG0460	homoserine dehydrogenase
BCV49_RS00465	COG0737	Belongs to the 5'-nucleotidase family
BCV49_RS00475	COG0583	DNA-binding transcription factor activity
BCV49_RS00485	COG0697	spore germination
BCV49_RS00490	COG0371	Dehydrogenase
BCV49_RS00500	COG2207	Transcriptional regulator
BCV49_RS00505	COG3443	Belongs to the bacterial solute-binding protein 9 family
BCV49_RS00520	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BCV49_RS00535	COG0583	DNA-binding transcription factor activity
BCV49_RS00610	COG3085	chromosome segregation
BCV49_RS00630	COG3978	acetolactate synthase activity
BCV49_RS00645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCV49_RS00650	COG0583	DNA-binding transcription factor activity
BCV49_RS00660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCV49_RS00665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCV49_RS00675	COG1811	Na channel or pump
BCV49_RS00700	COG3118	belongs to the thioredoxin family
BCV49_RS00705	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCV49_RS00710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCV49_RS00720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BCV49_RS00725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BCV49_RS00730	COG1088	dTDP-glucose 4,6-dehydratase activity
BCV49_RS00735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BCV49_RS00740	COG0456	acetyltransferase
BCV49_RS00745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BCV49_RS00750	COG2244	polysaccharide biosynthetic process
BCV49_RS00800	COG3071	HemY protein
BCV49_RS00805	COG2959	enzyme of heme biosynthesis
BCV49_RS00825	COG3072	Adenylate cyclase
BCV49_RS00855	COG1011	Hydrolase
BCV49_RS00860	COG0210	DNA helicase
BCV49_RS00895	COG1280	lysine exporter protein (LysE YggA)
BCV49_RS00905	COG1280	lysine exporter protein (LysE YggA)
BCV49_RS00910	COG2267	carboxylic ester hydrolase activity
BCV49_RS00915	COG0561	phosphatase activity
BCV49_RS00920	COG0697	spore germination
BCV49_RS00925	COG0583	DNA-binding transcription factor activity
BCV49_RS00955	COG3165	ubiquinone biosynthetic process from chorismate
BCV49_RS00975	COG0805	protein transport
BCV49_RS01020	COG1739	Uncharacterized protein family UPF0029
BCV49_RS01030	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BCV49_RS01105	COG0250	Participates in transcription elongation, termination and antitermination
BCV49_RS01140	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BCV49_RS01145	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCV49_RS01155	COG3706	GGDEF domain
BCV49_RS01175	COG2104	thiamine diphosphate biosynthetic process
BCV49_RS01180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCV49_RS01195	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BCV49_RS01230	COG3678	ATP-independent chaperone mediated protein folding
BCV49_RS01240	COG4191	Histidine kinase
BCV49_RS01250	COG0151	Belongs to the GarS family
BCV49_RS01290	COG0456	acetyltransferase
BCV49_RS01300	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BCV49_RS01350	COG0527	aspartate kinase activity
BCV49_RS01360	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BCV49_RS01370	COG0251	oxidation-reduction process
BCV49_RS01440	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCV49_RS01450	COG0534	Mate efflux family protein
BCV49_RS01460	COG3237	CsbD-like
BCV49_RS01465	COG0735	belongs to the Fur family
BCV49_RS01480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCV49_RS01495	COG0305	Participates in initiation and elongation during chromosome replication
BCV49_RS01500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCV49_RS01515	COG0432	Pfam Uncharacterised protein family UPF0047
BCV49_RS01520	COG2315	Protein conserved in bacteria
BCV49_RS01535	COG0741	lytic transglycosylase activity
BCV49_RS01545	COG4771	TonB-dependent receptor
BCV49_RS01570	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV49_RS01580	COG0483	inositol monophosphate 1-phosphatase activity
BCV49_RS01585	COG1609	Transcriptional regulator
BCV49_RS01590	COG1234	tRNA 3'-trailer cleavage
BCV49_RS01620	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BCV49_RS01630	COG0789	Transcriptional regulator
BCV49_RS01635	COG0625	glutathione transferase activity
BCV49_RS01640	COG2252	PERMEase
BCV49_RS01645	COG0025	NhaP-type Na H and K H
BCV49_RS01650	COG0583	DNA-binding transcription factor activity
BCV49_RS01655	COG1380	Effector of murein hydrolase LrgA
BCV49_RS01660	COG1346	cytolysis
BCV49_RS01670	COG3539	Fimbrial protein
BCV49_RS01700	COG3162	membrane
BCV49_RS01710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCV49_RS01720	COG1301	dicarboxylic acid transport
BCV49_RS01725	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BCV49_RS01730	COG3383	formate dehydrogenase (NAD+) activity
BCV49_RS01735	COG3383	formate dehydrogenase (NAD+) activity
BCV49_RS01760	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS01765	COG1129	ABC transporter
BCV49_RS01770	COG4191	Histidine kinase
BCV49_RS01770	COG0784	Response regulator, receiver
BCV49_RS01780	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BCV49_RS01790	COG3454	Phosphonate metabolism
BCV49_RS01795	COG4778	phosphonate C-P lyase system protein PhnL
BCV49_RS01800	COG4107	phosphonate C-P lyase system protein PhnK
BCV49_RS01805	COG3627	carbon phosphorus lyase activity
BCV49_RS01810	COG3626	phosphonate metabolism
BCV49_RS01815	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BCV49_RS01820	COG3624	Phosphonate C-P lyase system protein PhnG
BCV49_RS01825	COG2188	Transcriptional regulator
BCV49_RS01830	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BCV49_RS01835	COG2824	Alkylphosphonate utilization operon protein PhnA
BCV49_RS01850	COG2169	Transcriptional regulator
BCV49_RS01855	COG1486	melibiose metabolic process
BCV49_RS01895	COG0861	Integral membrane protein TerC family
BCV49_RS01915	COG1215	transferase activity, transferring glycosyl groups
BCV49_RS01920	COG1649	PFAM Uncharacterised BCR, COG1649
BCV49_RS01920	COG0726	polysaccharide deacetylase
BCV49_RS01925	COG0457	Tetratricopeptide repeat
BCV49_RS01965	COG1309	transcriptional regulator
BCV49_RS01980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BCV49_RS01985	COG1027	Aspartate ammonia-lyase
BCV49_RS01995	COG3030	protein affecting phage T7 exclusion by the F plasmid
BCV49_RS02000	COG0531	amino acid
BCV49_RS02070	COG1509	lysine 2,3-aminomutase activity
BCV49_RS02085	COG5510	response to toxic substance
BCV49_RS02090	COG2076	Multidrug Resistance protein
BCV49_RS02110	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCV49_RS02115	COG1053	succinate dehydrogenase
BCV49_RS02130	COG3264	Mechanosensitive ion channel
BCV49_RS02130	COG1511	domain protein
BCV49_RS02150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV49_RS02175	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCV49_RS02180	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BCV49_RS02180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BCV49_RS02185	COG0802	atpase or kinase
BCV49_RS02190	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV49_RS02210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCV49_RS02215	COG0330	HflC and HflK could
BCV49_RS02220	COG0330	HflC and HflK could
BCV49_RS02235	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BCV49_RS02250	COG0557	exoribonuclease II activity
BCV49_RS02255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCV49_RS02260	COG1960	acyl-CoA dehydrogenase activity
BCV49_RS02270	COG3650	response to hydrogen peroxide
BCV49_RS02275	COG1073	alpha beta
BCV49_RS02335	COG2965	DNA replication, synthesis of RNA primer
BCV49_RS02340	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BCV49_RS02350	COG3061	Opacity-associated protein A
BCV49_RS02355	COG0545	Peptidyl-prolyl cis-trans isomerase
BCV49_RS02360	COG1113	amino acid transport
BCV49_RS02370	COG0697	spore germination
BCV49_RS02380	COG0702	epimerase
BCV49_RS02385	COG1733	regulation of RNA biosynthetic process
BCV49_RS02400	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BCV49_RS02415	COG1253	flavin adenine dinucleotide binding
BCV49_RS02425	COG0729	surface antigen
BCV49_RS02430	COG2911	Protein conserved in bacteria
BCV49_RS02435	COG2105	PFAM AIG2 family protein
BCV49_RS02450	COG1879	ABC-type sugar transport system periplasmic component
BCV49_RS02460	COG1129	ABC transporter
BCV49_RS02465	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS02470	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS02480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCV49_RS02505	COG0312	modulator of DNA gyrase
BCV49_RS02545	COG3964	amidohydrolase
BCV49_RS02560	COG2706	6-phosphogluconolactonase activity
BCV49_RS02565	COG3711	transcriptional antiterminator
BCV49_RS02565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS02570	COG3077	Addiction module antitoxin, RelB DinJ family
BCV49_RS02575	COG2026	Addiction module toxin, RelE StbE family
BCV49_RS02580	COG0602	queuosine metabolic process
BCV49_RS02610	COG1486	melibiose metabolic process
BCV49_RS02620	COG0366	Alpha amylase catalytic
BCV49_RS02625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV49_RS02625	COG1263	PTS System
BCV49_RS02655	COG2731	YhcH YjgK YiaL family protein
BCV49_RS02680	COG0525	valine-tRNA ligase activity
BCV49_RS02685	COG2927	DNA polymerase III (CHI subunit)
BCV49_RS02695	COG0795	lipopolysaccharide-transporting ATPase activity
BCV49_RS02700	COG0795	lipopolysaccharide-transporting ATPase activity
BCV49_RS02705	COG0433	COG0433 Predicted ATPase
BCV49_RS02725	COG3718	enzyme involved in inositol metabolism
BCV49_RS02745	COG0837	glucose binding
BCV49_RS02745	COG1737	Transcriptional regulator
BCV49_RS02750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV49_RS02760	COG3962	Belongs to the TPP enzyme family
BCV49_RS02770	COG1082	Xylose isomerase domain protein TIM barrel
BCV49_RS02785	COG3842	ATPase activity
BCV49_RS02790	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BCV49_RS02795	COG0395	ABC-type sugar transport system, permease component
BCV49_RS02800	COG1175	transmembrane transport
BCV49_RS02805	COG1064	alcohol dehydrogenase
BCV49_RS02810	COG0659	secondary active sulfate transmembrane transporter activity
BCV49_RS02815	COG0288	reversible hydration of carbon dioxide
BCV49_RS02825	COG0582	viral genome integration into host DNA
BCV49_RS02910	COG0582	viral genome integration into host DNA
BCV49_RS02920	COG3121	Chaperone
BCV49_RS02940	COG0673	inositol 2-dehydrogenase activity
BCV49_RS02945	COG3732	PTS system glucitol sorbitol-specific
BCV49_RS02960	COG3423	Transcriptional regulator
BCV49_RS03065	COG0071	Belongs to the small heat shock protein (HSP20) family
BCV49_RS03175	COG2801	Transposase and inactivated derivatives
BCV49_RS03180	COG1216	Glycosyl transferase, family 2
BCV49_RS03190	COG3328	transposase activity
BCV49_RS03200	COG3507	Belongs to the glycosyl hydrolase 43 family
BCV49_RS03205	COG2211	Major facilitator Superfamily
BCV49_RS03210	COG2115	Belongs to the xylose isomerase family
BCV49_RS03215	COG4580	involved in the transport of maltose and maltodextrins
BCV49_RS03220	COG3272	Protein of unknown function (DUF1722)
BCV49_RS03240	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BCV49_RS03255	COG0300	oxidoreductase activity
BCV49_RS03260	COG3631	Ketosteroid isomerase-related protein
BCV49_RS03265	COG0789	Transcriptional regulator
BCV49_RS03270	COG3040	lipid binding
BCV49_RS03280	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV49_RS03285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV49_RS03290	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV49_RS03295	COG1538	Outer membrane efflux protein
BCV49_RS03305	COG0745	RESPONSE REGULATOR receiver
BCV49_RS03310	COG5002	protein histidine kinase activity
BCV49_RS03325	COG2850	peptidyl-arginine hydroxylation
BCV49_RS03360	COG0842	Transport permease protein
BCV49_RS03365	COG0842	Transport permease protein
BCV49_RS03365	COG1129	ABC transporter
BCV49_RS03380	COG1879	ABC-type sugar transport system periplasmic component
BCV49_RS03385	COG1129	ABC transporter
BCV49_RS03390	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS03400	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCV49_RS03405	COG0583	DNA-binding transcription factor activity
BCV49_RS03415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV49_RS03420	COG5457	Domain of unknown function (DUF1127)
BCV49_RS03430	COG1566	PFAM secretion protein HlyD family protein
BCV49_RS03445	COG1924	4 iron, 4 sulfur cluster binding
BCV49_RS03450	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BCV49_RS03465	COG2733	membrane
BCV49_RS03475	COG2207	Transcriptional regulator
BCV49_RS03475	COG1917	Cupin 2, conserved barrel domain protein
BCV49_RS03480	COG5464	transposase or invertase
BCV49_RS03485	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS03495	COG0523	cobalamin synthesis protein
BCV49_RS03500	COG2879	small protein
BCV49_RS03505	COG1966	Carbon starvation protein
BCV49_RS03520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BCV49_RS03525	COG2368	4-hydroxyphenylacetate
BCV49_RS03545	COG3971	2-oxopent-4-enoate hydratase activity
BCV49_RS03555	COG3384	dioxygenase
BCV49_RS03560	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS03570	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCV49_RS03580	COG1846	Transcriptional regulator
BCV49_RS03610	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BCV49_RS03625	COG3734	2-keto-3-deoxy-galactonokinase
BCV49_RS03630	COG0800	Aldolase
BCV49_RS03635	COG1737	Transcriptional regulator
BCV49_RS03650	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCV49_RS03650	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BCV49_RS03665	COG3715	PTS system
BCV49_RS03670	COG3716	PTS system mannose fructose sorbose family IID component
BCV49_RS03675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCV49_RS03685	COG5464	transposase or invertase
BCV49_RS03700	COG1484	DNA-dependent DNA replication
BCV49_RS03715	COG2966	Psort location CytoplasmicMembrane, score
BCV49_RS03735	COG2197	response regulator
BCV49_RS03740	COG2197	response regulator
BCV49_RS03745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCV49_RS03750	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV49_RS03750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV49_RS03755	COG4114	ferric iron reductase
BCV49_RS03760	COG3706	GGDEF domain
BCV49_RS03795	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BCV49_RS03800	COG0456	acetyltransferase
BCV49_RS03805	COG1011	Hydrolase
BCV49_RS03815	COG2823	Periplasmic or secreted lipoprotein
BCV49_RS03825	COG4667	esterase of the alpha-beta hydrolase superfamily
BCV49_RS03830	COG0084	hydrolase, TatD family'
BCV49_RS03835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCV49_RS03865	COG3726	membrane protein affecting hemolysin expression
BCV49_RS03870	COG0560	Phosphoserine phosphatase
BCV49_RS03875	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BCV49_RS03885	COG0488	(ABC) transporter
BCV49_RS03890	COG0741	lytic transglycosylase activity
BCV49_RS03910	COG2207	Transcriptional regulator
BCV49_RS03910	COG3708	Transcriptional regulator
BCV49_RS03915	COG3045	CreA protein
BCV49_RS03920	COG0745	RESPONSE REGULATOR receiver
BCV49_RS03925	COG2205	protein histidine kinase activity
BCV49_RS03930	COG4452	Inner membrane protein CreD
BCV49_RS03935	COG0745	RESPONSE REGULATOR receiver
BCV49_RS03940	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BCV49_RS03950	COG0460	homoserine dehydrogenase
BCV49_RS03950	COG0527	aspartate kinase activity
BCV49_RS03960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BCV49_RS03975	COG1115	amino acid carrier protein
BCV49_RS03980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCV49_RS03985	COG0521	Mo-molybdopterin cofactor biosynthetic process
BCV49_RS03990	COG0477	Major facilitator Superfamily
BCV49_RS03995	COG1584	GPR1 FUN34 yaaH family protein
BCV49_RS04000	COG4735	regulation of single-species biofilm formation
BCV49_RS04025	COG0583	DNA-binding transcription factor activity
BCV49_RS04040	COG0196	riboflavin kinase activity
BCV49_RS04055	COG1047	Peptidyl-prolyl cis-trans
BCV49_RS04080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCV49_RS04100	COG0505	Belongs to the CarA family
BCV49_RS04145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BCV49_RS04155	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BCV49_RS04160	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BCV49_RS04175	COG3493	citrate carrier protein
BCV49_RS04190	COG0564	pseudouridine synthase activity
BCV49_RS04200	COG0417	DNA replication proofreading
BCV49_RS04205	COG0235	Class ii aldolase
BCV49_RS04230	COG0586	Pfam SNARE associated Golgi protein
BCV49_RS04240	COG1178	ABC-type Fe3 transport system permease component
BCV49_RS04265	COG2814	Major facilitator Superfamily
BCV49_RS04270	COG2271	Major facilitator Superfamily
BCV49_RS04275	COG0583	DNA-binding transcription factor activity
BCV49_RS04285	COG0738	Major facilitator superfamily
BCV49_RS04330	COG0028	Belongs to the TPP enzyme family
BCV49_RS04340	COG1609	Transcriptional regulator
BCV49_RS04360	COG0768	penicillin binding
BCV49_RS04365	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCV49_RS04370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCV49_RS04385	COG0772	Belongs to the SEDS family
BCV49_RS04410	COG0849	cell division
BCV49_RS04415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCV49_RS04435	COG0494	nUDIX hydrolase
BCV49_RS04465	COG1459	type II secretion system
BCV49_RS04470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCV49_RS04475	COG4969	Belongs to the N-Me-Phe pilin family
BCV49_RS04485	COG3023	N-Acetylmuramoyl-L-alanine amidase
BCV49_RS04490	COG3725	Membrane protein required for beta-lactamase induction
BCV49_RS04495	COG3940	Belongs to the glycosyl hydrolase 43 family
BCV49_RS04500	COG2211	Major facilitator Superfamily
BCV49_RS04505	COG1113	amino acid transport
BCV49_RS04515	COG2186	Transcriptional regulator
BCV49_RS04520	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BCV49_RS04525	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCV49_RS04530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCV49_RS04545	COG3064	Membrane
BCV49_RS04590	COG2132	Multicopper oxidase
BCV49_RS04595	COG4993	Dehydrogenase
BCV49_RS04610	COG0288	reversible hydration of carbon dioxide
BCV49_RS04615	COG1131	(ABC) transporter
BCV49_RS04620	COG0842	Transport permease protein
BCV49_RS04625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS04630	COG0726	polysaccharide deacetylase
BCV49_RS04650	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCV49_RS04655	COG0617	tRNA 3'-terminal CCA addition
BCV49_RS04675	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BCV49_RS04680	COG1643	Atp-dependent helicase
BCV49_RS04780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCV49_RS04785	COG4774	siderophore transport
BCV49_RS04790	COG1120	ATPase activity
BCV49_RS04795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCV49_RS04800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV49_RS04820	COG2860	membrane
BCV49_RS04840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV49_RS04845	COG3835	regulator
BCV49_RS04860	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BCV49_RS04865	COG0024	Methionine aminopeptidase
BCV49_RS04890	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BCV49_RS04900	COG0575	Belongs to the CDS family
BCV49_RS04905	COG0750	zinc metalloprotease
BCV49_RS04915	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BCV49_RS04945	COG0587	DNA-directed DNA polymerase activity
BCV49_RS04955	COG1982	Orn Lys Arg decarboxylase major
BCV49_RS04960	COG0346	lactoylglutathione lyase activity
BCV49_RS04970	COG4568	rho-dependent transcription termination
BCV49_RS04985	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCV49_RS04990	COG3015	lipoprotein NlpE involved in copper resistance
BCV49_RS04995	COG0791	NLP P60 protein
BCV49_RS05005	COG1720	tRNA m6t6A37 methyltransferase activity
BCV49_RS05015	COG1464	Belongs to the NlpA lipoprotein family
BCV49_RS05020	COG2011	ABC-type metal ion transport system permease component
BCV49_RS05030	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BCV49_RS05065	COG0656	L-ascorbic acid biosynthetic process
BCV49_RS05070	COG0583	DNA-binding transcription factor activity
BCV49_RS05075	COG2814	Major facilitator Superfamily
BCV49_RS05085	COG2226	methyltransferase
BCV49_RS05090	COG0741	lytic transglycosylase activity
BCV49_RS05090	COG1388	LysM domain
BCV49_RS05100	COG2226	methyltransferase
BCV49_RS05110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV49_RS05120	COG0583	DNA-binding transcription factor activity
BCV49_RS05130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCV49_RS05135	COG1960	acyl-CoA dehydrogenase activity
BCV49_RS05145	COG0121	glutamine amidotransferase
BCV49_RS05150	COG3034	peptidoglycan biosynthetic process
BCV49_RS05170	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BCV49_RS05175	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BCV49_RS05190	COG2991	Protein conserved in bacteria
BCV49_RS05205	COG0454	-acetyltransferase
BCV49_RS05210	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCV49_RS05230	COG1802	Transcriptional regulator
BCV49_RS05235	COG1113	amino acid transport
BCV49_RS05240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCV49_RS05245	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS05250	COG0579	oxidoreductase
BCV49_RS05265	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BCV49_RS05270	COG0625	glutathione transferase activity
BCV49_RS05275	COG3775	system Galactitol-specific IIC component
BCV49_RS05280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCV49_RS05285	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS05290	COG1070	Carbohydrate kinase
BCV49_RS05310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCV49_RS05315	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCV49_RS05320	COG0022	dehydrogenase e1 component
BCV49_RS05325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCV49_RS05330	COG2909	trisaccharide binding
BCV49_RS05340	COG2963	transposase activity
BCV49_RS05385	COG0791	NLP P60 protein
BCV49_RS05405	COG3639	organic phosphonate transmembrane transporter activity
BCV49_RS05415	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BCV49_RS05440	COG3188	usher protein
BCV49_RS05455	COG0765	amino acid transport
BCV49_RS05460	COG4597	amino acid ABC transporter
BCV49_RS05465	COG1126	abc transporter atp-binding protein
BCV49_RS05470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV49_RS05510	COG4302	ethanolamine ammonia-lyase activity
BCV49_RS05515	COG4303	Ethanolamine ammonia lyase large subunit
BCV49_RS05530	COG0833	amino acid
BCV49_RS05535	COG2040	homocysteine
BCV49_RS05540	COG4521	taurine ABC transporter
BCV49_RS05545	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BCV49_RS05550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCV49_RS05555	COG2175	clavaminate synthase activity
BCV49_RS05565	COG0113	porphobilinogen synthase activity
BCV49_RS05570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCV49_RS05575	COG1335	isochorismatase
BCV49_RS05580	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BCV49_RS05620	COG1785	Belongs to the alkaline phosphatase family
BCV49_RS05630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCV49_RS05640	COG3416	Protein conserved in bacteria
BCV49_RS05645	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCV49_RS05655	COG4126	flavin adenine dinucleotide binding
BCV49_RS05670	COG1940	carbohydrate kinase activity
BCV49_RS05680	COG0420	3'-5' exonuclease activity
BCV49_RS05705	COG0366	Alpha amylase catalytic
BCV49_RS05710	COG0583	DNA-binding transcription factor activity
BCV49_RS05715	COG1335	isochorismatase
BCV49_RS05725	COG1228	amidohydrolase
BCV49_RS05735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV49_RS05750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS05760	COG0450	alkyl hydroperoxide reductase
BCV49_RS05785	COG1862	Preprotein translocase
BCV49_RS05790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCV49_RS05795	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCV49_RS05815	COG4238	major outer membrane lipoprotein
BCV49_RS05825	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCV49_RS05825	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCV49_RS05845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BCV49_RS05850	COG0667	Aldo Keto reductase
BCV49_RS05860	COG0142	geranyltranstransferase activity
BCV49_RS05880	COG0693	protein deglycase activity
BCV49_RS05885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCV49_RS05895	COG2814	Major facilitator Superfamily
BCV49_RS05900	COG0673	inositol 2-dehydrogenase activity
BCV49_RS05915	COG1053	succinate dehydrogenase
BCV49_RS05925	COG1053	succinate dehydrogenase
BCV49_RS05930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BCV49_RS05935	COG1414	Transcriptional regulator
BCV49_RS05950	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCV49_RS05955	COG1845	cytochrome c oxidase, subunit III
BCV49_RS05960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCV49_RS05965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCV49_RS05970	COG2223	nitrite transmembrane transporter activity
BCV49_RS05975	COG3056	Lipoprotein
BCV49_RS05980	COG0271	Belongs to the BolA IbaG family
BCV49_RS06000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BCV49_RS06005	COG0776	regulation of translation
BCV49_RS06010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCV49_RS06015	COG1555	photosystem II stabilization
BCV49_RS06020	COG0824	Thioesterase
BCV49_RS06030	COG4533	DNA binding
BCV49_RS06045	COG1522	sequence-specific DNA binding
BCV49_RS06050	COG1132	(ABC) transporter
BCV49_RS06055	COG1132	(ABC) transporter
BCV49_RS06060	COG0347	Belongs to the P(II) protein family
BCV49_RS06065	COG0004	ammonium transporteR
BCV49_RS06070	COG1946	Acyl-CoA thioesterase
BCV49_RS06075	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BCV49_RS06080	COG3695	enzyme binding
BCV49_RS06110	COG2364	Membrane
BCV49_RS06125	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BCV49_RS06140	COG2182	Extracellular solute-binding protein
BCV49_RS06145	COG1175	transmembrane transport
BCV49_RS06150	COG3833	ABC-type maltose transport systems, permease component
BCV49_RS06155	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BCV49_RS06160	COG1874	Beta-galactosidase
BCV49_RS06210	COG0110	maltose O-acetyltransferase activity
BCV49_RS06225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV49_RS06230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV49_RS06235	COG1309	transcriptional regulator
BCV49_RS06240	COG1196	nuclear chromosome segregation
BCV49_RS06240	COG3264	Mechanosensitive ion channel
BCV49_RS06255	COG3923	Primosomal replication protein n
BCV49_RS06260	COG2832	Protein of unknown function (DUF454)
BCV49_RS06300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV49_RS06305	COG4651	solute:proton antiporter activity
BCV49_RS06305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCV49_RS06320	COG2223	nitrite transmembrane transporter activity
BCV49_RS06330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCV49_RS06335	COG3735	TraB family
BCV49_RS06350	COG1585	Membrane protein implicated in regulation of membrane protease activity
BCV49_RS06355	COG0330	HflC and HflK could
BCV49_RS06360	COG4619	ABC transporter
BCV49_RS06365	COG0390	transport system, permease component
BCV49_RS06370	COG3118	belongs to the thioredoxin family
BCV49_RS06375	COG0300	oxidoreductase activity
BCV49_RS06380	COG2755	lipolytic protein G-D-S-L family
BCV49_RS06385	COG4181	ATPase activity
BCV49_RS06390	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BCV49_RS06425	COG3960	tartronate-semialdehyde synthase activity
BCV49_RS06430	COG3622	Belongs to the hyi family
BCV49_RS06435	COG2084	Dehydrogenase
BCV49_RS06445	COG1953	Uracil, thiamine, allantoin
BCV49_RS06455	COG2233	PERMEase
BCV49_RS06460	COG1929	Belongs to the glycerate kinase type-1 family
BCV49_RS06465	COG3257	ureidoglycine aminohydrolase activity
BCV49_RS06470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCV49_RS06475	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BCV49_RS06480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCV49_RS06485	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCV49_RS06495	COG0549	Belongs to the carbamate kinase family
BCV49_RS06500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BCV49_RS06505	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BCV49_RS06520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCV49_RS06540	COG1988	membrane-bound metal-dependent
BCV49_RS06545	COG2501	S4 domain
BCV49_RS06595	COG3539	Fimbrial protein
BCV49_RS06600	COG3121	Chaperone
BCV49_RS06605	COG3188	usher protein
BCV49_RS06620	COG1560	Kdo2-lipid A biosynthetic process
BCV49_RS06630	COG3710	Transcriptional regulator
BCV49_RS06635	COG0531	amino acid
BCV49_RS06640	COG1982	Orn Lys Arg decarboxylase major
BCV49_RS06645	COG3104	oligopeptide transport
BCV49_RS06675	COG0673	inositol 2-dehydrogenase activity
BCV49_RS06690	COG1129	ABC transporter
BCV49_RS06695	COG4211	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS06750	COG1566	PFAM secretion protein HlyD family protein
BCV49_RS06755	COG1120	ATPase activity
BCV49_RS06760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV49_RS06795	COG1473	amidohydrolase
BCV49_RS06800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV49_RS06805	COG0667	Aldo Keto reductase
BCV49_RS06850	COG0531	amino acid
BCV49_RS06860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV49_RS06865	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS06880	COG1113	amino acid transport
BCV49_RS06885	COG2211	Major facilitator Superfamily
BCV49_RS06895	COG0673	inositol 2-dehydrogenase activity
BCV49_RS06905	COG1609	Transcriptional regulator
BCV49_RS06910	COG0668	transmembrane transport
BCV49_RS06915	COG0477	Major facilitator Superfamily
BCV49_RS06930	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BCV49_RS06930	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCV49_RS06935	COG2222	sugar isomerase
BCV49_RS06940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCV49_RS06945	COG3716	PTS system mannose fructose sorbose family IID component
BCV49_RS06955	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV49_RS06965	COG0778	Nitroreductase
BCV49_RS06970	COG2315	Protein conserved in bacteria
BCV49_RS07015	COG3698	Phosphodiester glycosidase
BCV49_RS07035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV49_RS07040	COG4608	Belongs to the ABC transporter superfamily
BCV49_RS07055	COG0697	spore germination
BCV49_RS07070	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BCV49_RS07075	COG0765	amino acid transport
BCV49_RS07080	COG4215	(ABC) transporter
BCV49_RS07090	COG4221	oxidoreductase activity
BCV49_RS07095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCV49_RS07105	COG2801	Transposase and inactivated derivatives
BCV49_RS07115	COG4608	Belongs to the ABC transporter superfamily
BCV49_RS07120	COG0444	Belongs to the ABC transporter superfamily
BCV49_RS07125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV49_RS07130	COG0601	transmembrane transport
BCV49_RS07135	COG0747	negative chemotaxis
BCV49_RS07160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCV49_RS07170	COG0668	transmembrane transport
BCV49_RS07175	COG0583	DNA-binding transcription factor activity
BCV49_RS07185	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS07195	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS07200	COG1129	ABC transporter
BCV49_RS07210	COG1879	ABC-type sugar transport system periplasmic component
BCV49_RS07215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BCV49_RS07220	COG2390	Transcriptional regulator
BCV49_RS07225	COG3959	Transketolase, thiamine diphosphate binding domain
BCV49_RS07230	COG3958	Transketolase
BCV49_RS07235	COG2977	Belongs to the P-Pant transferase superfamily
BCV49_RS07240	COG4771	TonB-dependent receptor
BCV49_RS07245	COG2382	esterase
BCV49_RS07250	COG3251	PFAM MbtH domain protein
BCV49_RS07255	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BCV49_RS07255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV49_RS07260	COG1120	ATPase activity
BCV49_RS07265	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV49_RS07270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV49_RS07280	COG4592	Periplasmic binding protein
BCV49_RS07285	COG1169	isochorismate synthase
BCV49_RS07290	COG1021	2,3-dihydroxybenzoate-AMP ligase
BCV49_RS07295	COG3433	isochorismatase activity
BCV49_RS07295	COG1535	isochorismatase
BCV49_RS07300	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS07310	COG1966	Carbon starvation protein
BCV49_RS07315	COG2879	small protein
BCV49_RS07330	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS07335	COG0371	Dehydrogenase
BCV49_RS07340	COG1129	ABC transporter
BCV49_RS07345	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS07375	COG2271	Major facilitator Superfamily
BCV49_RS07380	COG0483	inositol monophosphate 1-phosphatase activity
BCV49_RS07390	COG0402	S-adenosylhomocysteine deaminase activity
BCV49_RS07400	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BCV49_RS07415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCV49_RS07425	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS07430	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS07435	COG1129	ABC transporter
BCV49_RS07460	COG0436	Aminotransferase
BCV49_RS07465	COG1475	DNA binding
BCV49_RS07470	COG3969	phosphoadenosine phosphosulfate
BCV49_RS07475	COG0583	DNA-binding transcription factor activity
BCV49_RS07480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV49_RS07500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCV49_RS07505	COG3719	Belongs to the RNase T2 family
BCV49_RS07510	COG3069	C4-dicarboxylate transmembrane transporter activity
BCV49_RS07530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCV49_RS07535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCV49_RS07545	COG0583	DNA-binding transcription factor activity
BCV49_RS07560	COG1686	Belongs to the peptidase S11 family
BCV49_RS07565	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BCV49_RS07570	COG0772	Belongs to the SEDS family
BCV49_RS07575	COG0768	penicillin binding
BCV49_RS07585	COG0799	negative regulation of ribosome biogenesis
BCV49_RS07600	COG1466	dna polymerase III delta subunit
BCV49_RS07615	COG2888	peptidyl-tyrosine sulfation
BCV49_RS07635	COG1126	abc transporter atp-binding protein
BCV49_RS07640	COG0765	amino acid transport
BCV49_RS07645	COG0765	amino acid transport
BCV49_RS07670	COG1702	phosphate starvation-inducible protein PhoH
BCV49_RS07680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV49_RS07720	COG0367	asparagine synthase
BCV49_RS07725	COG0647	UMP catabolic process
BCV49_RS07730	COG1846	Transcriptional regulator
BCV49_RS07730	COG1940	carbohydrate kinase activity
BCV49_RS07735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCV49_RS07775	COG0735	belongs to the Fur family
BCV49_RS07790	COG0596	Alpha beta hydrolase
BCV49_RS07805	COG0033	Phosphoglucomutase
BCV49_RS07815	COG0745	RESPONSE REGULATOR receiver
BCV49_RS07820	COG2205	protein histidine kinase activity
BCV49_RS07845	COG0415	Belongs to the DNA photolyase family
BCV49_RS07860	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BCV49_RS07865	COG1984	allophanate hydrolase subunit 2
BCV49_RS07905	COG2009	succinate dehydrogenase
BCV49_RS07910	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BCV49_RS07915	COG1053	succinate dehydrogenase
BCV49_RS07920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCV49_RS07925	COG0567	Dehydrogenase, E1 component
BCV49_RS07930	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCV49_RS07940	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCV49_RS07950	COG1271	oxidase subunit
BCV49_RS07955	COG1294	oxidase, subunit
BCV49_RS07960	COG4890	Cyd operon protein YbgT
BCV49_RS07965	COG3790	cyd operon protein YbgE
BCV49_RS07970	COG0824	Thioesterase
BCV49_RS07975	COG0811	peptide transport
BCV49_RS07980	COG0848	biopolymer transport protein
BCV49_RS07985	COG3064	Membrane
BCV49_RS07995	COG2885	chlorophyll binding
BCV49_RS08000	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BCV49_RS08070	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BCV49_RS08075	COG3201	nicotinamide mononucleotide transporter
BCV49_RS08090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCV49_RS08100	COG2017	converts alpha-aldose to the beta-anomer
BCV49_RS08110	COG1085	galactose-1-phosphate uridylyltransferase
BCV49_RS08120	COG1119	ATPase activity
BCV49_RS08125	COG3585	molybdate ion transport
BCV49_RS08125	COG2005	Transcriptional regulator
BCV49_RS08135	COG0725	ABC transporter, periplasmic molybdate-binding protein
BCV49_RS08140	COG4149	molybdate abc transporter
BCV49_RS08145	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BCV49_RS08150	COG0561	phosphatase activity
BCV49_RS08175	COG2200	EAL domain
BCV49_RS08180	COG0789	Transcriptional regulator
BCV49_RS08215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV49_RS08220	COG0589	response to stress
BCV49_RS08230	COG4677	pectinesterase activity
BCV49_RS08265	COG1881	PFAM PEBP family protein
BCV49_RS08270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCV49_RS08285	COG2226	methyltransferase
BCV49_RS08310	COG0642	Histidine kinase
BCV49_RS08315	COG0745	RESPONSE REGULATOR receiver
BCV49_RS08335	COG0521	Mo-molybdopterin cofactor biosynthetic process
BCV49_RS08345	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BCV49_RS08350	COG0314	molybdopterin synthase activity
BCV49_RS08355	COG0670	Belongs to the BI1 family
BCV49_RS08360	COG0392	lysyltransferase activity
BCV49_RS08365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV49_RS08370	COG3568	Endonuclease Exonuclease Phosphatase
BCV49_RS08380	COG0842	Transport permease protein
BCV49_RS08385	COG0842	Transport permease protein
BCV49_RS08390	COG1131	(ABC) transporter
BCV49_RS08395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV49_RS08400	COG1309	transcriptional regulator
BCV49_RS08405	COG0583	DNA-binding transcription factor activity
BCV49_RS08415	COG2271	Major facilitator Superfamily
BCV49_RS08420	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS08425	COG3959	Transketolase, thiamine diphosphate binding domain
BCV49_RS08430	COG3958	Transketolase
BCV49_RS08435	COG0513	Belongs to the DEAD box helicase family
BCV49_RS08440	COG1199	ATP-dependent helicase activity
BCV49_RS08445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCV49_RS08455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCV49_RS08465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BCV49_RS08475	COG0668	transmembrane transport
BCV49_RS08480	COG1126	abc transporter atp-binding protein
BCV49_RS08485	COG0765	amino acid transport
BCV49_RS08490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV49_RS08510	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BCV49_RS08515	COG2194	sulfuric ester hydrolase activity
BCV49_RS08530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCV49_RS08535	COG2723	6-phospho-beta-galactosidase activity
BCV49_RS08540	COG2188	Transcriptional regulator
BCV49_RS08545	COG1376	ErfK ybiS ycfS ynhG family protein
BCV49_RS08550	COG2365	Tyrosine phosphatase family
BCV49_RS08555	COG0488	(ABC) transporter
BCV49_RS08565	COG2271	Major facilitator Superfamily
BCV49_RS08570	COG1609	Transcriptional regulator
BCV49_RS08580	COG0561	phosphatase activity
BCV49_RS08585	COG1882	Formate acetyltransferase
BCV49_RS08590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCV49_RS08595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCV49_RS08600	COG0303	'Molybdopterin
BCV49_RS08615	COG0747	negative chemotaxis
BCV49_RS08635	COG2223	nitrite transmembrane transporter activity
BCV49_RS08645	COG2133	pyrroloquinoline quinone binding
BCV49_RS08650	COG0625	glutathione transferase activity
BCV49_RS08660	COG1686	Belongs to the peptidase S11 family
BCV49_RS08665	COG1349	DNA-binding transcription factor activity
BCV49_RS08670	COG0671	phosphoesterase, PA-phosphatase related
BCV49_RS08675	COG2814	Major facilitator Superfamily
BCV49_RS08680	COG0561	phosphatase activity
BCV49_RS08685	COG0738	Major facilitator superfamily
BCV49_RS08690	COG3226	Transcriptional regulator
BCV49_RS08720	COG0778	Nitroreductase
BCV49_RS08735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BCV49_RS08740	COG3842	ATPase activity
BCV49_RS08745	COG1176	ABC-type spermidine putrescine transport system, permease component I
BCV49_RS08750	COG1177	transmembrane transport
BCV49_RS08765	COG0745	RESPONSE REGULATOR receiver
BCV49_RS08770	COG5002	protein histidine kinase activity
BCV49_RS08775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV49_RS08780	COG4160	amino acid transport
BCV49_RS08785	COG4215	(ABC) transporter
BCV49_RS08790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV49_RS08795	COG1126	abc transporter atp-binding protein
BCV49_RS08805	COG2203	Gaf domain
BCV49_RS08805	COG4251	negative regulation of phosphorylation
BCV49_RS08805	COG5001	Diguanylate cyclase
BCV49_RS08805	COG3706	GGDEF domain
BCV49_RS08810	COG3023	N-Acetylmuramoyl-L-alanine amidase
BCV49_RS08815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV49_RS08820	COG0702	epimerase
BCV49_RS08825	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BCV49_RS08830	COG0028	Belongs to the TPP enzyme family
BCV49_RS08840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV49_RS08850	COG2431	L-lysine efflux transmembrane transporter activity
BCV49_RS08860	COG3593	DNA synthesis involved in DNA repair
BCV49_RS08865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV49_RS08875	COG1278	Cold shock
BCV49_RS08885	COG0542	response to heat
BCV49_RS08900	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BCV49_RS08905	COG4988	ABC transporter
BCV49_RS08910	COG0492	ferredoxin-NADP+ reductase activity
BCV49_RS08925	COG1178	ABC-type Fe3 transport system permease component
BCV49_RS08925	COG1674	ftsk spoiiie
BCV49_RS08935	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCV49_RS08945	COG0243	molybdopterin cofactor binding
BCV49_RS08950	COG0437	4 iron, 4 sulfur cluster binding
BCV49_RS08955	COG3302	dmso reductase anchor subunit
BCV49_RS08965	COG0477	Major facilitator Superfamily
BCV49_RS08970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCV49_RS08975	COG1882	Formate acetyltransferase
BCV49_RS08980	COG2116	formate transmembrane transporter activity
BCV49_RS08985	COG1944	ATP diphosphatase activity
BCV49_RS08990	COG2323	membrane
BCV49_RS09010	COG0539	negative regulation of cytoplasmic translation
BCV49_RS09020	COG2333	competence protein COMEC
BCV49_RS09020	COG0658	competence protein
BCV49_RS09035	COG3214	Protein conserved in bacteria
BCV49_RS09050	COG3173	Aminoglycoside phosphotransferase
BCV49_RS09055	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BCV49_RS09060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCV49_RS09070	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BCV49_RS09080	COG2989	Protein conserved in bacteria
BCV49_RS09085	COG3108	Peptidase M15
BCV49_RS09090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV49_RS09095	COG1448	Aminotransferase
BCV49_RS09100	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BCV49_RS09110	COG1522	sequence-specific DNA binding
BCV49_RS09120	COG0814	amino acid
BCV49_RS09130	COG1473	amidohydrolase
BCV49_RS09145	COG0308	aminopeptidase N
BCV49_RS09155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCV49_RS09160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV49_RS09165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCV49_RS09170	COG0431	NADPH-dependent FMN reductase
BCV49_RS09185	COG0633	Ferredoxin
BCV49_RS09185	COG3217	Mosc domain protein beta barrel domain protein
BCV49_RS09195	COG0488	(ABC) transporter
BCV49_RS09200	COG2995	paraquat-inducible protein a
BCV49_RS09205	COG3008	intermembrane lipid transfer
BCV49_RS09205	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCV49_RS09210	COG3009	Protein conserved in bacteria
BCV49_RS09215	COG3130	regulation of translation
BCV49_RS09225	COG1067	ATP-dependent peptidase activity
BCV49_RS09250	COG3070	regulator of competence-specific genes
BCV49_RS09255	COG1289	transmembrane transporter activity
BCV49_RS09260	COG3304	Inner membrane component domain
BCV49_RS09265	COG0210	DNA helicase
BCV49_RS09275	COG1832	CoA-binding protein
BCV49_RS09290	COG1881	PFAM PEBP family protein
BCV49_RS09295	COG2207	Transcriptional regulator
BCV49_RS09310	COG0670	Belongs to the BI1 family
BCV49_RS09325	COG0058	SHG alpha-glucan phosphorylase activity
BCV49_RS09335	COG2200	EAL domain
BCV49_RS09360	COG3706	GGDEF domain
BCV49_RS09365	COG2207	Transcriptional regulator
BCV49_RS09375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV49_RS09380	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCV49_RS09385	COG1882	Formate acetyltransferase
BCV49_RS09390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV49_RS09395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV49_RS09400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS09400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS09400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCV49_RS09405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV49_RS09410	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS09415	COG4638	Rieske (2fe-2S)
BCV49_RS09420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCV49_RS09425	COG0473	3-isopropylmalate dehydrogenase activity
BCV49_RS09430	COG0583	DNA-binding transcription factor activity
BCV49_RS09435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV49_RS09440	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS09445	COG1396	sequence-specific DNA binding
BCV49_RS09445	COG1917	Cupin 2, conserved barrel domain protein
BCV49_RS09450	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BCV49_RS09455	COG0174	glutamine synthetase
BCV49_RS09460	COG0531	amino acid
BCV49_RS09475	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS09505	COG3729	General stress protein
BCV49_RS09515	COG2233	PERMEase
BCV49_RS09550	COG1309	transcriptional regulator
BCV49_RS09565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCV49_RS09575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCV49_RS09595	COG1702	phosphate starvation-inducible protein PhoH
BCV49_RS09600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV49_RS09610	COG1335	isochorismatase
BCV49_RS09620	COG0583	DNA-binding transcription factor activity
BCV49_RS09640	COG3381	protein complex oligomerization
BCV49_RS09675	COG5645	(Lipo)protein
BCV49_RS09690	COG1560	Kdo2-lipid A biosynthetic process
BCV49_RS09740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV49_RS09760	COG2814	Major facilitator Superfamily
BCV49_RS09765	COG0583	DNA-binding transcription factor activity
BCV49_RS09770	COG1530	ribonuclease E activity
BCV49_RS09785	COG1399	metal-binding, possibly nucleic acid-binding protein
BCV49_RS09805	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCV49_RS09820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCV49_RS09825	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCV49_RS09830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCV49_RS09840	COG0470	DNA polymerase III
BCV49_RS09845	COG0084	hydrolase, TatD family'
BCV49_RS09855	COG0537	adenosine 5'-monophosphoramidase activity
BCV49_RS09860	COG5633	Lipoprotein
BCV49_RS09885	COG1252	NADH dehydrogenase
BCV49_RS09890	COG3134	Outer membrane lipoprotein
BCV49_RS09905	COG1309	transcriptional regulator
BCV49_RS09920	COG1388	LysM domain
BCV49_RS09920	COG1376	ErfK ybiS ycfS ynhG family protein
BCV49_RS09925	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCV49_RS09935	COG4591	ABC-type transport system involved in lipoprotein release permease component
BCV49_RS09945	COG4591	ABC-type transport system involved in lipoprotein release permease component
BCV49_RS09955	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BCV49_RS09965	COG2390	Transcriptional regulator
BCV49_RS09980	COG3395	kinase activity
BCV49_RS09995	COG0698	ribose 5-phosphate isomerase
BCV49_RS10000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCV49_RS10005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCV49_RS10010	COG0318	PFAM AMP-dependent synthetase and ligase
BCV49_RS10025	COG1177	transmembrane transport
BCV49_RS10045	COG1943	Transposase
BCV49_RS10050	COG2850	peptidyl-arginine hydroxylation
BCV49_RS10055	COG2205	protein histidine kinase activity
BCV49_RS10075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BCV49_RS10095	COG1187	pseudouridine synthase activity
BCV49_RS10100	COG0538	isocitrate dehydrogenase activity
BCV49_RS10105	COG0582	viral genome integration into host DNA
BCV49_RS10115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV49_RS10180	COG1403	HNH endonuclease
BCV49_RS10205	COG3772	lysozyme
BCV49_RS10235	COG4626	Terminase
BCV49_RS10235	COG1802	Transcriptional regulator
BCV49_RS10245	COG0616	signal peptide processing
BCV49_RS10325	COG3706	GGDEF domain
BCV49_RS10330	COG5001	Diguanylate cyclase
BCV49_RS10330	COG3300	MHYT domain
BCV49_RS10335	COG0640	Transcriptional regulator
BCV49_RS10355	COG3813	Protein conserved in bacteria
BCV49_RS10360	COG1063	alcohol dehydrogenase
BCV49_RS10370	COG3729	General stress protein
BCV49_RS10375	COG3685	Protein conserved in bacteria
BCV49_RS10380	COG3685	Protein conserved in bacteria
BCV49_RS10385	COG3546	catalase activity
BCV49_RS10390	COG1271	oxidase subunit
BCV49_RS10395	COG1294	oxidase, subunit
BCV49_RS10425	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BCV49_RS10430	COG0583	DNA-binding transcription factor activity
BCV49_RS10435	COG3706	GGDEF domain
BCV49_RS10440	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BCV49_RS10460	COG1560	Kdo2-lipid A biosynthetic process
BCV49_RS10470	COG3182	Iron-regulated membrane protein
BCV49_RS10485	COG2199	diguanylate cyclase activity
BCV49_RS10485	COG2203	Gaf domain
BCV49_RS10490	COG3042	response to heat
BCV49_RS10495	COG3189	MarR family transcriptional regulator
BCV49_RS10500	COG1683	Conserved Protein
BCV49_RS10505	COG0504	CTP synthase activity
BCV49_RS10510	COG2807	transmembrane transport
BCV49_RS10515	COG2207	Transcriptional regulator
BCV49_RS10525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCV49_RS10530	COG0859	PFAM glycosyl transferase family 9
BCV49_RS10540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCV49_RS10545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCV49_RS10550	COG0583	DNA-binding transcription factor activity
BCV49_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS10580	COG0386	Belongs to the glutathione peroxidase family
BCV49_RS10595	COG2766	serine protein kinase
BCV49_RS10600	COG3713	MltA-interacting MipA family protein
BCV49_RS10605	COG0656	L-ascorbic acid biosynthetic process
BCV49_RS10625	COG3139	Protein of unknown function (DUF1315)
BCV49_RS10640	COG1335	isochorismatase
BCV49_RS10645	COG0252	asparaginase activity
BCV49_RS10650	COG0616	signal peptide processing
BCV49_RS10655	COG0778	Nitroreductase
BCV49_RS10665	COG0709	Synthesizes selenophosphate from selenide and ATP
BCV49_RS10670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCV49_RS10675	COG3321	synthase
BCV49_RS10675	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS10675	COG0604	alcohol dehydrogenase
BCV49_RS10680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCV49_RS10690	COG0494	nUDIX hydrolase
BCV49_RS10695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCV49_RS10700	COG2897	thiosulfate sulfurtransferase activity
BCV49_RS10705	COG4136	ATPase activity
BCV49_RS10710	COG4135	transport system, permease component
BCV49_RS10715	COG4134	Bacterial extracellular solute-binding protein
BCV49_RS10720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCV49_RS10725	COG0398	Pfam SNARE associated Golgi protein
BCV49_RS10730	COG0398	Pfam SNARE associated Golgi protein
BCV49_RS10735	COG0708	Exodeoxyribonuclease III
BCV49_RS10745	COG3138	arginine N-succinyltransferase
BCV49_RS10755	COG3724	N-succinylarginine dihydrolase activity
BCV49_RS10770	COG3678	ATP-independent chaperone mediated protein folding
BCV49_RS10775	COG0322	excinuclease ABC activity
BCV49_RS10785	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV49_RS10790	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV49_RS10800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV49_RS10805	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCV49_RS10810	COG1917	Cupin 2, conserved barrel domain protein
BCV49_RS10810	COG2169	Transcriptional regulator
BCV49_RS10815	COG1486	melibiose metabolic process
BCV49_RS10825	COG0753	catalase activity
BCV49_RS10835	COG1823	symporter activity
BCV49_RS10840	COG1988	membrane-bound metal-dependent
BCV49_RS10845	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS10850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV49_RS10880	COG0727	PFAM Uncharacterised protein family (UPF0153)
BCV49_RS10885	COG3047	cAMP biosynthetic process
BCV49_RS10895	COG4774	siderophore transport
BCV49_RS10950	COG0135	phosphoribosylanthranilate isomerase activity
BCV49_RS10950	COG0134	indole-3-glycerol-phosphate synthase activity
BCV49_RS10955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCV49_RS10955	COG0512	Glutamine amidotransferase of anthranilate synthase
BCV49_RS10960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCV49_RS10970	COG0009	L-threonylcarbamoyladenylate synthase
BCV49_RS10980	COG0583	DNA-binding transcription factor activity
BCV49_RS10990	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BCV49_RS10995	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS11005	COG0616	signal peptide processing
BCV49_RS11040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCV49_RS11050	COG0671	phosphoesterase, PA-phosphatase related
BCV49_RS11055	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BCV49_RS11060	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BCV49_RS11070	COG0023	Translation Initiation Factor
BCV49_RS11085	COG1349	DNA-binding transcription factor activity
BCV49_RS11100	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCV49_RS11100	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCV49_RS11110	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BCV49_RS11120	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BCV49_RS11135	COG4171	peptide transport system, permease
BCV49_RS11150	COG0702	epimerase
BCV49_RS11165	COG1473	amidohydrolase
BCV49_RS11175	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCV49_RS11180	COG1842	Phage shock protein A
BCV49_RS11190	COG1983	PspC domain protein
BCV49_RS11200	COG3106	COG3106 Predicted ATPase
BCV49_RS11210	COG0583	DNA-binding transcription factor activity
BCV49_RS11215	COG1486	melibiose metabolic process
BCV49_RS11225	COG3180	Ammonia monooxygenase
BCV49_RS11230	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BCV49_RS11235	COG4948	Mandelate Racemase Muconate Lactonizing
BCV49_RS11240	COG2866	Carboxypeptidase
BCV49_RS11250	COG4166	transmembrane transport
BCV49_RS11305	COG0656	L-ascorbic acid biosynthetic process
BCV49_RS11310	COG3250	beta-galactosidase activity
BCV49_RS11315	COG2205	protein histidine kinase activity
BCV49_RS11315	COG0784	Response regulator, receiver
BCV49_RS11315	COG5002	protein histidine kinase activity
BCV49_RS11370	COG0583	DNA-binding transcription factor activity
BCV49_RS11375	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS11380	COG1078	dGTPase activity
BCV49_RS11385	COG0693	protein deglycase activity
BCV49_RS11415	COG2885	chlorophyll binding
BCV49_RS11440	COG1388	LysM domain
BCV49_RS11440	COG1705	Flagellar rod assembly protein muramidase FlgJ
BCV49_RS11450	COG2801	Transposase and inactivated derivatives
BCV49_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS11510	COG1309	transcriptional regulator
BCV49_RS11515	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS11535	COG0583	DNA-binding transcription factor activity
BCV49_RS11560	COG0604	alcohol dehydrogenase
BCV49_RS11565	COG0436	Aminotransferase
BCV49_RS11580	COG2011	ABC-type metal ion transport system permease component
BCV49_RS11585	COG1448	Aminotransferase
BCV49_RS11595	COG1522	sequence-specific DNA binding
BCV49_RS11600	COG1113	amino acid transport
BCV49_RS11615	COG0673	inositol 2-dehydrogenase activity
BCV49_RS11620	COG1349	DNA-binding transcription factor activity
BCV49_RS11630	COG0513	Belongs to the DEAD box helicase family
BCV49_RS11640	COG0589	response to stress
BCV49_RS11650	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BCV49_RS11655	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV49_RS11655	COG0674	pyruvate-flavodoxin oxidoreductase activity
BCV49_RS11655	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BCV49_RS11655	COG1013	pyruvate-flavodoxin oxidoreductase activity
BCV49_RS11660	COG3042	response to heat
BCV49_RS11665	COG3187	Heat shock protein
BCV49_RS11670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCV49_RS11675	COG0586	Pfam SNARE associated Golgi protein
BCV49_RS11680	COG2911	Protein conserved in bacteria
BCV49_RS11690	COG3784	Protein of unknown function (DUF1318)
BCV49_RS11695	COG2207	Transcriptional regulator
BCV49_RS11700	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS11720	COG2030	dehydratase
BCV49_RS11720	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS11725	COG3396	Phenylacetate-CoA oxygenase
BCV49_RS11730	COG3460	Phenylacetate-CoA oxygenase
BCV49_RS11735	COG3396	Phenylacetate-CoA oxygenase
BCV49_RS11740	COG2151	metal-sulfur cluster biosynthetic enzyme
BCV49_RS11745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV49_RS11750	COG1024	Enoyl-CoA hydratase
BCV49_RS11755	COG1024	Enoyl-CoA hydratase
BCV49_RS11760	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCV49_RS11765	COG2050	protein possibly involved in aromatic compounds catabolism
BCV49_RS11770	COG0183	Belongs to the thiolase family
BCV49_RS11775	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BCV49_RS11780	COG3327	negative regulation of DNA-templated transcription, initiation
BCV49_RS11785	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCV49_RS11800	COG1643	Atp-dependent helicase
BCV49_RS11805	COG4122	O-methyltransferase activity
BCV49_RS11830	COG0583	DNA-binding transcription factor activity
BCV49_RS11835	COG0667	Aldo Keto reductase
BCV49_RS11840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCV49_RS11850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCV49_RS11855	COG3138	arginine N-succinyltransferase
BCV49_RS11860	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS11865	COG3724	N-succinylarginine dihydrolase activity
BCV49_RS11870	COG2988	succinylglutamate desuccinylase activity
BCV49_RS11875	COG1113	amino acid transport
BCV49_RS11880	COG0477	Major facilitator Superfamily
BCV49_RS11885	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BCV49_RS11895	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS11900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCV49_RS11905	COG0401	homolog of Blt101
BCV49_RS11910	COG5562	phage envelope protein
BCV49_RS11915	COG0425	Belongs to the sulfur carrier protein TusA family
BCV49_RS11920	COG2391	methyltransferase activity
BCV49_RS11945	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BCV49_RS11950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV49_RS11950	COG1263	PTS System
BCV49_RS11955	COG1609	Transcriptional regulator
BCV49_RS11960	COG5339	Protein conserved in bacteria
BCV49_RS11965	COG1482	cell wall glycoprotein biosynthetic process
BCV49_RS11970	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BCV49_RS11970	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BCV49_RS11975	COG0114	fumarate hydratase activity
BCV49_RS11985	COG2205	protein histidine kinase activity
BCV49_RS11995	COG0745	RESPONSE REGULATOR receiver
BCV49_RS12000	COG3136	membrane protein required for alginate biosynthesis
BCV49_RS12010	COG0531	amino acid
BCV49_RS12035	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BCV49_RS12040	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BCV49_RS12055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV49_RS12070	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BCV49_RS12075	COG1473	amidohydrolase
BCV49_RS12085	COG0583	DNA-binding transcription factor activity
BCV49_RS12090	COG2840	Smr protein MutS2
BCV49_RS12095	COG1414	Transcriptional regulator
BCV49_RS12105	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BCV49_RS12110	COG0183	Belongs to the thiolase family
BCV49_RS12120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCV49_RS12125	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCV49_RS12135	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BCV49_RS12135	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BCV49_RS12160	COG4565	transcriptional regulatory protein
BCV49_RS12165	COG3290	protein histidine kinase activity
BCV49_RS12190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCV49_RS12200	COG0679	Auxin Efflux Carrier
BCV49_RS12230	COG0628	permease
BCV49_RS12250	COG3591	Belongs to the peptidase S1B family
BCV49_RS12270	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BCV49_RS12275	COG2814	Major facilitator Superfamily
BCV49_RS12280	COG0583	DNA-binding transcription factor activity
BCV49_RS12285	COG1940	carbohydrate kinase activity
BCV49_RS12290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BCV49_RS12305	COG3302	dmso reductase anchor subunit
BCV49_RS12310	COG0437	4 iron, 4 sulfur cluster binding
BCV49_RS12315	COG0243	molybdopterin cofactor binding
BCV49_RS12330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV49_RS12345	COG2271	Major facilitator Superfamily
BCV49_RS12350	COG0246	Mannitol dehydrogenase
BCV49_RS12355	COG0589	response to stress
BCV49_RS12360	COG1802	Transcriptional regulator
BCV49_RS12365	COG4221	oxidoreductase activity
BCV49_RS12380	COG2207	Transcriptional regulator
BCV49_RS12385	COG2135	peptidase activity
BCV49_RS12400	COG2197	response regulator
BCV49_RS12415	COG0071	Belongs to the small heat shock protein (HSP20) family
BCV49_RS12420	COG1546	Belongs to the CinA family
BCV49_RS12425	COG2200	EAL domain
BCV49_RS12435	COG3708	Transcriptional regulator
BCV49_RS12435	COG2207	Transcriptional regulator
BCV49_RS12440	COG2610	gluconate transmembrane transporter activity
BCV49_RS12445	COG3622	Belongs to the hyi family
BCV49_RS12450	COG0235	Class ii aldolase
BCV49_RS12455	COG3395	kinase activity
BCV49_RS12460	COG2084	Dehydrogenase
BCV49_RS12465	COG1349	DNA-binding transcription factor activity
BCV49_RS12480	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCV49_RS12485	COG2223	nitrite transmembrane transporter activity
BCV49_RS12520	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCV49_RS12555	COG2814	Major facilitator Superfamily
BCV49_RS12560	COG0697	spore germination
BCV49_RS12570	COG4977	sequence-specific DNA binding
BCV49_RS12600	COG2271	Major facilitator Superfamily
BCV49_RS12605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCV49_RS12610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCV49_RS12620	COG3395	kinase activity
BCV49_RS12625	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BCV49_RS12630	COG1349	DNA-binding transcription factor activity
BCV49_RS12635	COG0039	L-malate dehydrogenase activity
BCV49_RS12645	COG0583	DNA-binding transcription factor activity
BCV49_RS12650	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS12665	COG2199	diguanylate cyclase activity
BCV49_RS12730	COG0477	Major facilitator Superfamily
BCV49_RS12740	COG2070	2-Nitropropane dioxygenase
BCV49_RS12745	COG2011	ABC-type metal ion transport system permease component
BCV49_RS12775	COG2207	Transcriptional regulator
BCV49_RS12805	COG2233	PERMEase
BCV49_RS12810	COG3195	allantoin biosynthetic process
BCV49_RS12810	COG3648	Uricase
BCV49_RS12815	COG2351	hydroxyisourate hydrolase activity
BCV49_RS12820	COG1396	sequence-specific DNA binding
BCV49_RS12825	COG3550	peptidyl-serine autophosphorylation
BCV49_RS12830	COG1649	PFAM Uncharacterised BCR, COG1649
BCV49_RS12840	COG3188	usher protein
BCV49_RS12875	COG5001	Diguanylate cyclase
BCV49_RS12875	COG3300	MHYT domain
BCV49_RS12880	COG2819	hydrolase of the alpha beta superfamily
BCV49_RS12900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS12900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS12905	COG2814	Major facilitator Superfamily
BCV49_RS12920	COG1263	PTS System
BCV49_RS12920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV49_RS12925	COG2186	Transcriptional regulator
BCV49_RS12945	COG3835	regulator
BCV49_RS12950	COG1929	Belongs to the glycerate kinase type-1 family
BCV49_RS12995	COG0738	Major facilitator superfamily
BCV49_RS13000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCV49_RS13005	COG1349	DNA-binding transcription factor activity
BCV49_RS13020	COG1349	DNA-binding transcription factor activity
BCV49_RS13030	COG0667	Aldo Keto reductase
BCV49_RS13040	COG0667	Aldo Keto reductase
BCV49_RS13050	COG0456	acetyltransferase
BCV49_RS13050	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCV49_RS13075	COG1652	LysM domain
BCV49_RS13110	COG1609	Transcriptional regulator
BCV49_RS13120	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS13135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCV49_RS13145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV49_RS13150	COG0583	DNA-binding transcription factor activity
BCV49_RS13155	COG0583	DNA-binding transcription factor activity
BCV49_RS13175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV49_RS13185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCV49_RS13190	COG3037	sugar-specific permease SgaT UlaA
BCV49_RS13200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS13205	COG1609	Transcriptional regulator
BCV49_RS13215	COG2223	nitrite transmembrane transporter activity
BCV49_RS13245	COG0477	Major facilitator Superfamily
BCV49_RS13250	COG4529	Protein conserved in bacteria
BCV49_RS13255	COG1902	pentaerythritol trinitrate reductase activity
BCV49_RS13265	COG0583	DNA-binding transcription factor activity
BCV49_RS13270	COG2070	2-Nitropropane dioxygenase
BCV49_RS13280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BCV49_RS13290	COG0765	amino acid transport
BCV49_RS13335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCV49_RS13360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCV49_RS13385	COG2207	Transcriptional regulator
BCV49_RS13395	COG0596	Alpha beta hydrolase
BCV49_RS13430	COG1953	Uracil, thiamine, allantoin
BCV49_RS13435	COG0402	S-adenosylhomocysteine deaminase activity
BCV49_RS13440	COG3706	GGDEF domain
BCV49_RS13445	COG1609	Transcriptional regulator
BCV49_RS13455	COG0673	inositol 2-dehydrogenase activity
BCV49_RS13465	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BCV49_RS13470	COG1116	anion transmembrane transporter activity
BCV49_RS13475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCV49_RS13480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCV49_RS13485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCV49_RS13490	COG0076	glutamate decarboxylase activity
BCV49_RS13505	COG2205	protein histidine kinase activity
BCV49_RS13515	COG0596	Alpha beta hydrolase
BCV49_RS13555	COG0519	Catalyzes the synthesis of GMP from XMP
BCV49_RS13555	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCV49_RS13575	COG0583	DNA-binding transcription factor activity
BCV49_RS13585	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BCV49_RS13590	COG1285	pathogenesis
BCV49_RS13595	COG2814	Major facilitator Superfamily
BCV49_RS13600	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCV49_RS13605	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV49_RS13630	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV49_RS13635	COG0583	DNA-binding transcription factor activity
BCV49_RS13640	COG0243	molybdopterin cofactor binding
BCV49_RS13645	COG3781	membrane
BCV49_RS13670	COG1764	response to oxidative stress
BCV49_RS13680	COG3111	PFAM Bacterial OB fold (BOF) protein
BCV49_RS13690	COG2323	membrane
BCV49_RS13700	COG0366	Alpha amylase catalytic
BCV49_RS13710	COG3685	Protein conserved in bacteria
BCV49_RS13720	COG3729	General stress protein
BCV49_RS13725	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS13765	COG0488	(ABC) transporter
BCV49_RS13785	COG1064	alcohol dehydrogenase
BCV49_RS13790	COG0747	negative chemotaxis
BCV49_RS13800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV49_RS13810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV49_RS13820	COG2814	Major facilitator Superfamily
BCV49_RS13830	COG2326	polyphosphate kinase activity
BCV49_RS13840	COG2864	formate dehydrogenase
BCV49_RS13845	COG0437	4 iron, 4 sulfur cluster binding
BCV49_RS13850	COG3383	formate dehydrogenase (NAD+) activity
BCV49_RS13850	COG0243	molybdopterin cofactor binding
BCV49_RS13855	COG0243	molybdopterin cofactor binding
BCV49_RS13855	COG3383	formate dehydrogenase (NAD+) activity
BCV49_RS13875	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BCV49_RS13885	COG3485	protocatechuate 3,4-dioxygenase
BCV49_RS13890	COG4829	muconolactone delta-isomerase
BCV49_RS13895	COG4948	Mandelate Racemase Muconate Lactonizing
BCV49_RS13900	COG1414	Transcriptional regulator
BCV49_RS13915	COG2223	nitrite transmembrane transporter activity
BCV49_RS13920	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BCV49_RS13925	COG1140	nitrate reductase beta subunit
BCV49_RS13930	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BCV49_RS13935	COG2181	nitrate reductase activity
BCV49_RS13940	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BCV49_RS13945	COG1178	ABC-type Fe3 transport system permease component
BCV49_RS13950	COG1840	ABC-type Fe3 transport system, periplasmic component
BCV49_RS13955	COG3842	ATPase activity
BCV49_RS13960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BCV49_RS13970	COG0625	glutathione transferase activity
BCV49_RS13980	COG1126	abc transporter atp-binding protein
BCV49_RS13985	COG0765	amino acid transport
BCV49_RS13995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV49_RS14000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV49_RS14005	COG1473	amidohydrolase
BCV49_RS14010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV49_RS14015	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCV49_RS14040	COG4772	TonB-dependent receptor
BCV49_RS14045	COG1228	amidohydrolase
BCV49_RS14050	COG3691	Protein conserved in bacteria
BCV49_RS14065	COG2130	NADP-dependent
BCV49_RS14075	COG1247	-acetyltransferase
BCV49_RS14080	COG3238	Protein conserved in bacteria
BCV49_RS14090	COG0747	negative chemotaxis
BCV49_RS14100	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS14135	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS14140	COG1177	transmembrane transport
BCV49_RS14145	COG1176	ABC-type spermidine putrescine transport system, permease component I
BCV49_RS14150	COG3842	ATPase activity
BCV49_RS14155	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BCV49_RS14160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV49_RS14165	COG1271	oxidase subunit
BCV49_RS14170	COG1294	oxidase, subunit
BCV49_RS14190	COG0826	peptidase U32
BCV49_RS14200	COG1396	sequence-specific DNA binding
BCV49_RS14205	COG3135	benzoate transporter
BCV49_RS14210	COG2207	Transcriptional regulator
BCV49_RS14210	COG3708	Transcriptional regulator
BCV49_RS14215	COG0697	spore germination
BCV49_RS14225	COG0500	methyltransferase
BCV49_RS14230	COG1275	C4-dicarboxylate transporter malic acid transport protein
BCV49_RS14235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCV49_RS14240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV49_RS14255	COG2272	Belongs to the type-B carboxylesterase lipase family
BCV49_RS14260	COG5383	Protein conserved in bacteria
BCV49_RS14265	COG3485	protocatechuate 3,4-dioxygenase
BCV49_RS14270	COG3485	protocatechuate 3,4-dioxygenase
BCV49_RS14275	COG0583	DNA-binding transcription factor activity
BCV49_RS14295	COG3038	cytochrome b561
BCV49_RS14315	COG2814	Major facilitator Superfamily
BCV49_RS14325	COG0673	inositol 2-dehydrogenase activity
BCV49_RS14330	COG2723	6-phospho-beta-galactosidase activity
BCV49_RS14365	COG4659	FMN binding
BCV49_RS14375	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCV49_RS14390	COG0625	glutathione transferase activity
BCV49_RS14395	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BCV49_RS14410	COG3895	Periplasmic Protein
BCV49_RS14425	COG3706	GGDEF domain
BCV49_RS14440	COG1566	PFAM secretion protein HlyD family protein
BCV49_RS14445	COG1289	transmembrane transporter activity
BCV49_RS14450	COG2032	superoxide dismutase activity
BCV49_RS14455	COG4989	oxidoreductase activity
BCV49_RS14460	COG3313	Fe-S protein
BCV49_RS14465	COG1309	transcriptional regulator
BCV49_RS14470	COG1902	pentaerythritol trinitrate reductase activity
BCV49_RS14475	COG0346	lactoylglutathione lyase activity
BCV49_RS14485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BCV49_RS14490	COG0791	NLP P60 protein
BCV49_RS14505	COG2814	Major facilitator Superfamily
BCV49_RS14515	COG0583	DNA-binding transcription factor activity
BCV49_RS14520	COG2814	Major facilitator Superfamily
BCV49_RS14525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BCV49_RS14530	COG0307	riboflavin synthase, alpha
BCV49_RS14575	COG0300	oxidoreductase activity
BCV49_RS14595	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BCV49_RS14635	COG1349	DNA-binding transcription factor activity
BCV49_RS14640	COG0346	lactoylglutathione lyase activity
BCV49_RS14665	COG0444	Belongs to the ABC transporter superfamily
BCV49_RS14670	COG4608	Belongs to the ABC transporter superfamily
BCV49_RS14730	COG0402	S-adenosylhomocysteine deaminase activity
BCV49_RS14755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCV49_RS14760	COG0277	FAD linked oxidase domain protein
BCV49_RS14790	COG0583	DNA-binding transcription factor activity
BCV49_RS14800	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BCV49_RS14810	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCV49_RS14815	COG2610	gluconate transmembrane transporter activity
BCV49_RS14820	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS14855	COG2963	transposase activity
BCV49_RS14875	COG3088	subunit of a heme lyase
BCV49_RS14875	COG4235	cytochrome complex assembly
BCV49_RS14880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV49_RS14885	COG1138	Cytochrome C-type biogenesis protein
BCV49_RS14900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCV49_RS14905	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCV49_RS14910	COG4133	protoheme IX ABC transporter activity
BCV49_RS14940	COG3157	Type VI secretion system effector, Hcp
BCV49_RS14950	COG1518	maintenance of DNA repeat elements
BCV49_RS14960	COG1857	crispr-associated protein
BCV49_RS14995	COG1175	transmembrane transport
BCV49_RS15010	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BCV49_RS15015	COG3383	formate dehydrogenase (NAD+) activity
BCV49_RS15020	COG1473	amidohydrolase
BCV49_RS15050	COG1126	abc transporter atp-binding protein
BCV49_RS15055	COG0765	amino acid transport
BCV49_RS15080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV49_RS15085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV49_RS15090	COG1120	ATPase activity
BCV49_RS15095	COG4774	siderophore transport
BCV49_RS15100	COG1116	anion transmembrane transporter activity
BCV49_RS15105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCV49_RS15125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV49_RS15130	COG0583	DNA-binding transcription factor activity
BCV49_RS15150	COG2814	Major facilitator Superfamily
BCV49_RS15185	COG1414	Transcriptional regulator
BCV49_RS15190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCV49_RS15195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV49_RS15200	COG1120	ATPase activity
BCV49_RS15210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BCV49_RS15215	COG2271	Major facilitator Superfamily
BCV49_RS15220	COG1082	Xylose isomerase domain protein TIM barrel
BCV49_RS15220	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BCV49_RS15225	COG1309	transcriptional regulator
BCV49_RS15255	COG1376	ErfK ybiS ycfS ynhG family protein
BCV49_RS15270	COG0719	Fe-S assembly protein
BCV49_RS15275	COG0396	ATPase activity
BCV49_RS15280	COG0719	Fe-S assembly protein
BCV49_RS15285	COG0316	Belongs to the HesB IscA family
BCV49_RS15305	COG1309	transcriptional regulator
BCV49_RS15310	COG1304	FMN binding
BCV49_RS15335	COG0583	DNA-binding transcription factor activity
BCV49_RS15345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV49_RS15350	COG1120	ATPase activity
BCV49_RS15380	COG2261	transglycosylase associated protein
BCV49_RS15385	COG2050	protein possibly involved in aromatic compounds catabolism
BCV49_RS15390	COG0247	lactate metabolic process
BCV49_RS15390	COG0277	FAD linked oxidase domain protein
BCV49_RS15395	COG0628	permease
BCV49_RS15405	COG0574	Belongs to the PEP-utilizing enzyme family
BCV49_RS15405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCV49_RS15420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCV49_RS15425	COG4256	Hemin uptake protein
BCV49_RS15435	COG0791	NLP P60 protein
BCV49_RS15445	COG0386	Belongs to the glutathione peroxidase family
BCV49_RS15465	COG0583	DNA-binding transcription factor activity
BCV49_RS15485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCV49_RS15485	COG0072	phenylalanine-tRNA ligase activity
BCV49_RS15520	COG3137	Salt-induced outer membrane protein
BCV49_RS15525	COG1105	Belongs to the carbohydrate kinase PfkB family
BCV49_RS15545	COG2350	Protein conserved in bacteria
BCV49_RS15555	COG2353	YceI-like domain
BCV49_RS15575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV49_RS15585	COG0444	Belongs to the ABC transporter superfamily
BCV49_RS15590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV49_RS15595	COG0601	transmembrane transport
BCV49_RS15600	COG4166	transmembrane transport
BCV49_RS15610	COG2095	MarC family integral membrane protein
BCV49_RS15620	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS15620	COG1454	alcohol dehydrogenase
BCV49_RS15625	COG1435	thymidine kinase activity
BCV49_RS15635	COG2916	Histone family protein nucleoid-structuring protein H-NS
BCV49_RS15640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCV49_RS15645	COG0745	RESPONSE REGULATOR receiver
BCV49_RS15650	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCV49_RS15660	COG0788	formyltetrahydrofolate deformylase activity
BCV49_RS15695	COG1522	sequence-specific DNA binding
BCV49_RS15705	COG2181	nitrate reductase activity
BCV49_RS15710	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BCV49_RS15715	COG1140	nitrate reductase beta subunit
BCV49_RS15720	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BCV49_RS15730	COG2223	nitrite transmembrane transporter activity
BCV49_RS15735	COG3850	Histidine kinase
BCV49_RS15740	COG2197	response regulator
BCV49_RS15745	COG4932	domain protein
BCV49_RS15750	COG0243	molybdopterin cofactor binding
BCV49_RS15755	COG2146	nitrite reductase [NAD(P)H] activity
BCV49_RS15755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCV49_RS15760	COG1116	anion transmembrane transporter activity
BCV49_RS15770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCV49_RS15780	COG3707	response regulator
BCV49_RS15785	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BCV49_RS15795	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BCV49_RS15800	COG4572	Cation transport regulator
BCV49_RS15805	COG0387	Pfam Sodium calcium exchanger
BCV49_RS15825	COG2890	protein-(glutamine-N5) methyltransferase activity
BCV49_RS15855	COG0659	secondary active sulfate transmembrane transporter activity
BCV49_RS15875	COG0012	GTP binding
BCV49_RS15940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BCV49_RS15955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BCV49_RS15980	COG2885	chlorophyll binding
BCV49_RS16005	COG3122	Protein conserved in bacteria
BCV49_RS16020	COG0583	DNA-binding transcription factor activity
BCV49_RS16050	COG0583	DNA-binding transcription factor activity
BCV49_RS16085	COG1882	Formate acetyltransferase
BCV49_RS16100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCV49_RS16105	COG0583	DNA-binding transcription factor activity
BCV49_RS16150	COG2308	Evidence 4 Homologs of previously reported genes of
BCV49_RS16160	COG4774	siderophore transport
BCV49_RS16170	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCV49_RS16195	COG2719	SpoVR family
BCV49_RS16225	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCV49_RS16245	COG2894	cell division
BCV49_RS16255	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BCV49_RS16265	COG3065	identical protein binding
BCV49_RS16275	COG1199	ATP-dependent helicase activity
BCV49_RS16280	COG0251	oxidation-reduction process
BCV49_RS16300	COG1760	l-serine dehydratase
BCV49_RS16310	COG2200	EAL domain
BCV49_RS16315	COG1253	flavin adenine dinucleotide binding
BCV49_RS16320	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV49_RS16320	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS16325	COG3715	PTS system
BCV49_RS16330	COG3716	PTS system mannose fructose sorbose family IID component
BCV49_RS16345	COG2226	methyltransferase
BCV49_RS16350	COG0768	penicillin binding
BCV49_RS16380	COG1414	Transcriptional regulator
BCV49_RS16385	COG2814	Major facilitator Superfamily
BCV49_RS16405	COG1956	GAF domain-containing protein
BCV49_RS16410	COG2995	paraquat-inducible protein a
BCV49_RS16415	COG3008	intermembrane lipid transfer
BCV49_RS16440	COG2990	Protein conserved in bacteria
BCV49_RS16455	COG1276	copper resistance
BCV49_RS16460	COG2372	response to copper ion
BCV49_RS16470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV49_RS16475	COG1770	oligopeptidase
BCV49_RS16480	COG2979	Protein of unknown function (DUF533)
BCV49_RS16485	COG3141	response to X-ray
BCV49_RS16495	COG0800	Aldolase
BCV49_RS16500	COG0129	dihydroxy-acid dehydratase activity
BCV49_RS16505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCV49_RS16515	COG1737	Transcriptional regulator
BCV49_RS16525	COG1560	Kdo2-lipid A biosynthetic process
BCV49_RS16530	COG0739	heme binding
BCV49_RS16535	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BCV49_RS16545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCV49_RS16570	COG0494	nUDIX hydrolase
BCV49_RS16580	COG1335	isochorismatase
BCV49_RS16585	COG1801	Protein of unknown function DUF72
BCV49_RS16590	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BCV49_RS16610	COG3102	Protein conserved in bacteria
BCV49_RS16620	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BCV49_RS16645	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS16655	COG1879	ABC-type sugar transport system periplasmic component
BCV49_RS16660	COG1528	Iron-storage protein
BCV49_RS16670	COG2211	Major facilitator Superfamily
BCV49_RS16680	COG0477	Major facilitator Superfamily
BCV49_RS16695	COG1528	Iron-storage protein
BCV49_RS16705	COG0814	amino acid
BCV49_RS16710	COG3318	Belongs to the UPF0149 family
BCV49_RS16710	COG3012	SEC-C Motif Domain Protein
BCV49_RS16745	COG2197	response regulator
BCV49_RS16755	COG2197	response regulator
BCV49_RS16760	COG1126	abc transporter atp-binding protein
BCV49_RS16765	COG0765	amino acid transport
BCV49_RS16775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV49_RS16780	COG0366	Alpha amylase catalytic
BCV49_RS16810	COG2354	Protein conserved in bacteria
BCV49_RS16815	COG0697	spore germination
BCV49_RS16820	COG3727	T/G mismatch-specific endonuclease activity
BCV49_RS16825	COG0270	DNA (cytosine-5-)-methyltransferase activity
BCV49_RS16830	COG1418	mRNA catabolic process
BCV49_RS16840	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BCV49_RS16860	COG0251	oxidation-reduction process
BCV49_RS16875	COG1376	ErfK ybiS ycfS ynhG family protein
BCV49_RS16895	COG0582	viral genome integration into host DNA
BCV49_RS16900	COG1169	isochorismate synthase
BCV49_RS16905	COG2814	Major facilitator Superfamily
BCV49_RS16910	COG1132	(ABC) transporter
BCV49_RS16925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCV49_RS16925	COG2226	methyltransferase
BCV49_RS16925	COG3433	isochorismatase activity
BCV49_RS16945	COG1021	2,3-dihydroxybenzoate-AMP ligase
BCV49_RS16950	COG4771	TonB-dependent receptor
BCV49_RS17015	COG3504	Conjugal transfer protein
BCV49_RS17110	COG0025	NhaP-type Na H and K H
BCV49_RS17115	COG1309	transcriptional regulator
BCV49_RS17120	COG0604	alcohol dehydrogenase
BCV49_RS17140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BCV49_RS17150	COG0534	Mate efflux family protein
BCV49_RS17170	COG3706	GGDEF domain
BCV49_RS17195	COG3615	Tellurite resistance protein tehB
BCV49_RS17205	COG3300	MHYT domain
BCV49_RS17205	COG5001	Diguanylate cyclase
BCV49_RS17220	COG0477	Major facilitator Superfamily
BCV49_RS17225	COG0095	Lipoate-protein ligase
BCV49_RS17230	COG0583	DNA-binding transcription factor activity
BCV49_RS17235	COG1942	4-Oxalocrotonate Tautomerase
BCV49_RS17245	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BCV49_RS17265	COG1289	transmembrane transporter activity
BCV49_RS17280	COG2925	Exonuclease
BCV49_RS17285	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BCV49_RS17290	COG0640	Transcriptional regulator
BCV49_RS17295	COG0531	amino acid
BCV49_RS17300	COG0583	DNA-binding transcription factor activity
BCV49_RS17305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV49_RS17330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BCV49_RS17355	COG0463	Glycosyl transferase, family 2
BCV49_RS17365	COG1216	Glycosyl transferase, family 2
BCV49_RS17365	COG1442	glycosyl transferase family 8
BCV49_RS17370	COG0438	transferase activity, transferring glycosyl groups
BCV49_RS17440	COG0297	glycogen (starch) synthase activity
BCV49_RS17445	COG1051	belongs to the nudix hydrolase family
BCV49_RS17450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV49_RS17455	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BCV49_RS17510	COG1253	flavin adenine dinucleotide binding
BCV49_RS17515	COG2982	Protein involved in outer membrane biogenesis
BCV49_RS17530	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCV49_RS17535	COG0443	Heat shock 70 kDa protein
BCV49_RS17540	COG5002	protein histidine kinase activity
BCV49_RS17560	COG1301	dicarboxylic acid transport
BCV49_RS17585	COG2205	protein histidine kinase activity
BCV49_RS17590	COG0745	RESPONSE REGULATOR receiver
BCV49_RS17595	COG0826	peptidase U32
BCV49_RS17605	COG4608	Belongs to the ABC transporter superfamily
BCV49_RS17610	COG0444	Belongs to the ABC transporter superfamily
BCV49_RS17615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV49_RS17620	COG0601	transmembrane transport
BCV49_RS17625	COG0747	negative chemotaxis
BCV49_RS17630	COG4948	Mandelate Racemase Muconate Lactonizing
BCV49_RS17635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV49_RS17645	COG1070	Carbohydrate kinase
BCV49_RS17680	COG1830	Aldolase
BCV49_RS17685	COG0351	phosphomethylpyrimidine kinase
BCV49_RS17705	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BCV49_RS17715	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BCV49_RS17720	COG0583	DNA-binding transcription factor activity
BCV49_RS17730	COG2252	PERMEase
BCV49_RS17735	COG0583	DNA-binding transcription factor activity
BCV49_RS17740	COG5455	response to cobalt ion
BCV49_RS17760	COG4807	Protein conserved in bacteria
BCV49_RS17770	COG3275	phosphorelay sensor kinase activity
BCV49_RS17780	COG1174	glycine betaine transport
BCV49_RS17785	COG1125	glycine betaine transport
BCV49_RS17790	COG1174	glycine betaine transport
BCV49_RS17795	COG1732	Glycine betaine
BCV49_RS17800	COG1472	Belongs to the glycosyl hydrolase 3 family
BCV49_RS17805	COG0277	FAD linked oxidase domain protein
BCV49_RS17815	COG1686	Belongs to the peptidase S11 family
BCV49_RS17825	COG0586	Pfam SNARE associated Golgi protein
BCV49_RS17830	COG1538	Outer membrane efflux protein
BCV49_RS17840	COG2723	6-phospho-beta-galactosidase activity
BCV49_RS17855	COG3659	wide pore channel activity
BCV49_RS17860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCV49_RS17870	COG1346	cytolysis
BCV49_RS17880	COG2949	membrane
BCV49_RS17890	COG1129	ABC transporter
BCV49_RS17905	COG2311	Membrane
BCV49_RS17925	COG0833	amino acid
BCV49_RS17930	COG0583	DNA-binding transcription factor activity
BCV49_RS17940	COG2855	membrane
BCV49_RS17950	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BCV49_RS17950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV49_RS17950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV49_RS17955	COG1105	Belongs to the carbohydrate kinase PfkB family
BCV49_RS17960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS17960	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS17965	COG2814	Major facilitator Superfamily
BCV49_RS17980	COG1312	Catalyzes the dehydration of D-mannonate
BCV49_RS17985	COG0246	Mannitol dehydrogenase
BCV49_RS17990	COG0523	cobalamin synthesis protein
BCV49_RS17995	COG0671	phosphoesterase, PA-phosphatase related
BCV49_RS18000	COG0791	NLP P60 protein
BCV49_RS18005	COG2200	EAL domain
BCV49_RS18010	COG4166	transmembrane transport
BCV49_RS18015	COG4174	ABC transporter (Permease)
BCV49_RS18020	COG4239	(ABC) transporter, permease
BCV49_RS18025	COG4172	Belongs to the ABC transporter superfamily
BCV49_RS18035	COG2814	Major facilitator Superfamily
BCV49_RS18040	COG1187	pseudouridine synthase activity
BCV49_RS18045	COG1061	Type III restriction enzyme res subunit
BCV49_RS18065	COG0494	nUDIX hydrolase
BCV49_RS18070	COG1349	DNA-binding transcription factor activity
BCV49_RS18095	COG0628	permease
BCV49_RS18110	COG0659	secondary active sulfate transmembrane transporter activity
BCV49_RS18115	COG2239	Acts as a magnesium transporter
BCV49_RS18120	COG4615	Cyclic peptide transporter
BCV49_RS18125	COG3145	DNA-N1-methyladenine dioxygenase activity
BCV49_RS18130	COG2169	Transcriptional regulator
BCV49_RS18130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCV49_RS18145	COG0642	Histidine kinase
BCV49_RS18145	COG2198	Histidine kinase
BCV49_RS18155	COG2205	protein histidine kinase activity
BCV49_RS18155	COG0784	Response regulator, receiver
BCV49_RS18180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV49_RS18185	COG0584	glycerophosphoryl diester phosphodiesterase
BCV49_RS18190	COG2271	Major facilitator Superfamily
BCV49_RS18195	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCV49_RS18205	COG0247	lactate metabolic process
BCV49_RS18215	COG2271	Major facilitator Superfamily
BCV49_RS18225	COG1414	Transcriptional regulator
BCV49_RS18245	COG5464	transposase or invertase
BCV49_RS18255	COG0318	PFAM AMP-dependent synthetase and ligase
BCV49_RS18280	COG1169	isochorismate synthase
BCV49_RS18285	COG2153	protein acetylation
BCV49_RS18300	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV49_RS18305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCV49_RS18315	COG0839	Belongs to the complex I subunit 6 family
BCV49_RS18365	COG0583	DNA-binding transcription factor activity
BCV49_RS18370	COG0436	Aminotransferase
BCV49_RS18380	COG0490	domain, Protein
BCV49_RS18380	COG0471	metal ion transport
BCV49_RS18385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV49_RS18405	COG0280	phosphate acetyltransferase
BCV49_RS18405	COG0857	belongs to the CobB CobQ family
BCV49_RS18410	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BCV49_RS18415	COG0622	Phosphoesterase
BCV49_RS18420	COG0625	glutathione transferase activity
BCV49_RS18425	COG0625	glutathione transferase activity
BCV49_RS18430	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCV49_RS18435	COG1090	epimerase
BCV49_RS18450	COG4598	ABC transporter
BCV49_RS18455	COG4160	amino acid transport
BCV49_RS18480	COG0163	prenyltransferase activity
BCV49_RS18485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BCV49_RS18490	COG1286	toxin biosynthetic process
BCV49_RS18495	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BCV49_RS18500	COG0285	dihydrofolate synthase activity
BCV49_RS18510	COG0586	Pfam SNARE associated Golgi protein
BCV49_RS18520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCV49_RS18540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCV49_RS18555	COG3101	peptidyl-lysine hydroxylation
BCV49_RS18560	COG0730	response to heat
BCV49_RS18585	COG2062	phosphohistidine phosphatase, SixA
BCV49_RS18600	COG3691	Protein conserved in bacteria
BCV49_RS18610	COG2853	Lipoprotein
BCV49_RS18615	COG2116	formate transmembrane transporter activity
BCV49_RS18625	COG0582	viral genome integration into host DNA
BCV49_RS18815	COG3772	lysozyme
BCV49_RS18850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCV49_RS18950	COG4712	double-strand break repair protein
BCV49_RS19010	COG0583	DNA-binding transcription factor activity
BCV49_RS19015	COG0590	tRNA wobble adenosine to inosine editing
BCV49_RS19020	COG2807	transmembrane transport
BCV49_RS19025	COG0436	Aminotransferase
BCV49_RS19040	COG3275	phosphorelay sensor kinase activity
BCV49_RS19045	COG3279	Response regulator of the LytR AlgR family
BCV49_RS19060	COG3961	Belongs to the TPP enzyme family
BCV49_RS19065	COG0667	Aldo Keto reductase
BCV49_RS19080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCV49_RS19085	COG2199	diguanylate cyclase activity
BCV49_RS19085	COG2200	EAL domain
BCV49_RS19100	COG3415	Transposase
BCV49_RS19105	COG3415	Transposase
BCV49_RS19140	COG0583	DNA-binding transcription factor activity
BCV49_RS19145	COG0385	Bile acid
BCV49_RS19150	COG3530	Putative quorum-sensing-regulated virulence factor
BCV49_RS19175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCV49_RS19215	COG4319	ketosteroid isomerase
BCV49_RS19225	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BCV49_RS19230	COG4208	sulfate ABC transporter
BCV49_RS19235	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BCV49_RS19240	COG4150	thiosulfate binding
BCV49_RS19255	COG2837	iron assimilation
BCV49_RS19275	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV49_RS19365	COG4810	utilization protein
BCV49_RS19375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCV49_RS19380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCV49_RS19385	COG5342	invasion associated locus B
BCV49_RS19395	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV49_RS19395	COG0493	'glutamate synthase
BCV49_RS19400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV49_RS19405	COG1393	Belongs to the ArsC family
BCV49_RS19420	COG0400	carboxylic ester hydrolase activity
BCV49_RS19425	COG1444	tRNA N-acetyltransferase activity
BCV49_RS19430	COG2321	neutral zinc metallopeptidase
BCV49_RS19440	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BCV49_RS19450	COG2716	regulation of RNA biosynthetic process
BCV49_RS19455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCV49_RS19460	COG0628	permease
BCV49_RS19470	COG4783	chaperone-mediated protein folding
BCV49_RS19475	COG1393	Belongs to the ArsC family
BCV49_RS19490	COG2233	PERMEase
BCV49_RS19500	COG2723	6-phospho-beta-galactosidase activity
BCV49_RS19515	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCV49_RS19530	COG2200	EAL domain
BCV49_RS19550	COG0641	radical SAM
BCV49_RS19555	COG3119	arylsulfatase activity
BCV49_RS19690	COG3728	DNA packaging
BCV49_RS19690	COG5484	DNA packaging
BCV49_RS19745	COG3756	Protein conserved in bacteria
BCV49_RS19755	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCV49_RS19785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV49_RS19830	COG0517	IMP dehydrogenase activity
BCV49_RS19830	COG0516	GMP reductase activity
BCV49_RS19840	COG1645	bacterial-type flagellum-dependent swarming motility
BCV49_RS19860	COG2976	Protein conserved in bacteria
BCV49_RS19890	COG4953	penicillin-binding protein 1C
BCV49_RS19895	COG2373	Large extracellular alpha-helical protein
BCV49_RS19900	COG2897	thiosulfate sulfurtransferase activity
BCV49_RS19920	COG2975	iron-sulfur cluster assembly
BCV49_RS19925	COG0633	Ferredoxin
BCV49_RS19945	COG0822	iron-sulfur transferase activity
BCV49_RS19975	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BCV49_RS19980	COG3683	transport system, periplasmic component
BCV49_RS19990	COG2814	Major facilitator Superfamily
BCV49_RS19995	COG2017	converts alpha-aldose to the beta-anomer
BCV49_RS20000	COG2814	Major facilitator Superfamily
BCV49_RS20000	COG0477	Major facilitator Superfamily
BCV49_RS20005	COG0457	Tetratricopeptide repeat
BCV49_RS20015	COG2259	Doxx family
BCV49_RS20025	COG1017	nitric oxide dioxygenase activity
BCV49_RS20025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV49_RS20030	COG0347	Belongs to the P(II) protein family
BCV49_RS20035	COG2204	response regulator
BCV49_RS20040	COG3170	Tfp pilus assembly protein FimV
BCV49_RS20045	COG2205	protein histidine kinase activity
BCV49_RS20050	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCV49_RS20050	COG0047	phosphoribosylformylglycinamidine synthase activity
BCV49_RS20065	COG0560	Phosphoserine phosphatase
BCV49_RS20070	COG1737	Transcriptional regulator
BCV49_RS20075	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV49_RS20085	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BCV49_RS20110	COG0681	Belongs to the peptidase S26 family
BCV49_RS20120	COG3086	response to oxidative stress
BCV49_RS20125	COG3026	antisigma factor binding
BCV49_RS20130	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BCV49_RS20140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BCV49_RS20150	COG0513	Belongs to the DEAD box helicase family
BCV49_RS20165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCV49_RS20170	COG3118	belongs to the thioredoxin family
BCV49_RS20175	COG3148	PFAM DTW domain containing protein
BCV49_RS20185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV49_RS20190	COG5544	Lipoprotein
BCV49_RS20195	COG0477	Major facilitator Superfamily
BCV49_RS20225	COG0542	response to heat
BCV49_RS20240	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV49_RS20245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BCV49_RS20250	COG1605	Chorismate mutase
BCV49_RS20250	COG0077	Prephenate dehydratase
BCV49_RS20260	COG0287	Prephenate dehydrogenase
BCV49_RS20260	COG1605	Chorismate mutase
BCV49_RS20265	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCV49_RS20275	COG2199	diguanylate cyclase activity
BCV49_RS20280	COG2885	chlorophyll binding
BCV49_RS20320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCV49_RS20325	COG4137	Cytochrome C assembly protein
BCV49_RS20330	COG4536	flavin adenine dinucleotide binding
BCV49_RS20345	COG0497	DNA recombination
BCV49_RS20365	COG2867	negative regulation of translational initiation
BCV49_RS20395	COG2207	Transcriptional regulator
BCV49_RS20395	COG3708	Transcriptional regulator
BCV49_RS20400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV49_RS20425	COG3622	Belongs to the hyi family
BCV49_RS20430	COG0477	Major facilitator Superfamily
BCV49_RS20435	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BCV49_RS20440	COG2271	Major facilitator Superfamily
BCV49_RS20455	COG0431	NADPH-dependent FMN reductase
BCV49_RS20505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV49_RS20535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV49_RS20545	COG0235	Class ii aldolase
BCV49_RS20555	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS20570	COG2197	response regulator
BCV49_RS20585	COG3188	usher protein
BCV49_RS20605	COG3121	Chaperone
BCV49_RS20610	COG3539	Fimbrial protein
BCV49_RS20620	COG3284	Transcriptional regulator
BCV49_RS20625	COG0583	DNA-binding transcription factor activity
BCV49_RS20635	COG0640	Transcriptional regulator
BCV49_RS20640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCV49_RS20655	COG2916	Histone family protein nucleoid-structuring protein H-NS
BCV49_RS20675	COG4575	ribosome binding
BCV49_RS20680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV49_RS20685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCV49_RS20690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BCV49_RS20700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV49_RS20715	COG4176	ABC-type proline glycine betaine transport system permease component
BCV49_RS20725	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BCV49_RS20740	COG1846	Transcriptional regulator
BCV49_RS20750	COG1566	PFAM secretion protein HlyD family protein
BCV49_RS20755	COG2814	Major facilitator Superfamily
BCV49_RS20760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCV49_RS20780	COG1238	metal cluster binding
BCV49_RS20785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV49_RS20790	COG2823	Periplasmic or secreted lipoprotein
BCV49_RS20825	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BCV49_RS20845	COG1546	Belongs to the CinA family
BCV49_RS20855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCV49_RS20865	COG2951	lytic endotransglycosylase activity
BCV49_RS20870	COG3730	PTS system glucitol sorbitol-specific
BCV49_RS20875	COG3732	PTS system glucitol sorbitol-specific
BCV49_RS20885	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS20890	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS20895	COG1349	DNA-binding transcription factor activity
BCV49_RS20925	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BCV49_RS20930	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BCV49_RS20935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV49_RS20940	COG1609	Transcriptional regulator
BCV49_RS20950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV49_RS20950	COG1263	PTS System
BCV49_RS20955	COG2723	6-phospho-beta-galactosidase activity
BCV49_RS20965	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BCV49_RS20975	COG3260	NADH ubiquinone oxidoreductase 20
BCV49_RS20980	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV49_RS20985	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BCV49_RS20985	COG3261	NADH dehydrogenase
BCV49_RS20990	COG0650	Formate hydrogenlyase subunit 4
BCV49_RS20995	COG0651	ATP synthesis coupled electron transport
BCV49_RS21000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV49_RS21015	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BCV49_RS21020	COG0298	carbon dioxide binding
BCV49_RS21025	COG0409	Hydrogenase expression formation protein
BCV49_RS21030	COG0309	Hydrogenase expression formation protein (HypE)
BCV49_RS21040	COG2723	6-phospho-beta-galactosidase activity
BCV49_RS21050	COG4580	involved in the transport of maltose and maltodextrins
BCV49_RS21055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV49_RS21060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV49_RS21065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV49_RS21070	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCV49_RS21075	COG1940	carbohydrate kinase activity
BCV49_RS21080	COG1609	Transcriptional regulator
BCV49_RS21090	COG1121	(ABC) transporter
BCV49_RS21095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCV49_RS21100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCV49_RS21115	COG0679	Auxin Efflux Carrier
BCV49_RS21135	COG3720	iron ion transport
BCV49_RS21140	COG4558	Periplasmic binding protein
BCV49_RS21145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCV49_RS21170	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BCV49_RS21175	COG0163	prenyltransferase activity
BCV49_RS21200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCV49_RS21205	COG4942	peptidase
BCV49_RS21205	COG1388	LysM domain
BCV49_RS21265	COG2234	aminopeptidase activity
BCV49_RS21290	COG0720	synthase
BCV49_RS21295	COG0602	queuosine metabolic process
BCV49_RS21320	COG3956	TIGRFAM MazG family protein
BCV49_RS21325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCV49_RS21335	COG4999	Histidine kinase
BCV49_RS21335	COG3850	Histidine kinase
BCV49_RS21335	COG3437	response regulator, receiver
BCV49_RS21335	COG2205	protein histidine kinase activity
BCV49_RS21340	COG1929	Belongs to the glycerate kinase type-1 family
BCV49_RS21345	COG4948	Mandelate Racemase Muconate Lactonizing
BCV49_RS21350	COG4948	Mandelate Racemase Muconate Lactonizing
BCV49_RS21355	COG2271	Major facilitator Superfamily
BCV49_RS21360	COG0716	FMN binding
BCV49_RS21365	COG0564	pseudouridine synthase activity
BCV49_RS21370	COG3098	single-species biofilm formation
BCV49_RS21385	COG1611	Belongs to the LOG family
BCV49_RS21390	COG0814	amino acid
BCV49_RS21395	COG1760	l-serine dehydratase
BCV49_RS21410	COG0477	Major facilitator Superfamily
BCV49_RS21415	COG1464	Belongs to the NlpA lipoprotein family
BCV49_RS21420	COG2011	ABC-type metal ion transport system permease component
BCV49_RS21425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCV49_RS21440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV49_RS21460	COG1454	alcohol dehydrogenase
BCV49_RS21465	COG0235	Class ii aldolase
BCV49_RS21475	COG0738	Major facilitator superfamily
BCV49_RS21495	COG1349	DNA-binding transcription factor activity
BCV49_RS21505	COG2363	Small membrane protein
BCV49_RS21510	COG0583	DNA-binding transcription factor activity
BCV49_RS21520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCV49_RS21525	COG2166	iron-sulfur cluster assembly
BCV49_RS21530	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCV49_RS21535	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BCV49_RS21700	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BCV49_RS21730	COG1454	alcohol dehydrogenase
BCV49_RS21730	COG1012	belongs to the aldehyde dehydrogenase family
BCV49_RS21735	COG4656	Part of a membrane complex involved in electron transport
BCV49_RS21765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BCV49_RS21770	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV49_RS21775	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BCV49_RS21775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BCV49_RS21785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV49_RS21790	COG1074	ATP-dependent DNA helicase activity
BCV49_RS21795	COG1025	Belongs to the peptidase M16 family
BCV49_RS21800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BCV49_RS21805	COG4967	type IV pilus modification protein PilV
BCV49_RS21815	COG4795	General secretion pathway protein
BCV49_RS21820	COG2165	general secretion pathway protein
BCV49_RS21855	COG0861	Integral membrane protein TerC family
BCV49_RS21865	COG0667	Aldo Keto reductase
BCV49_RS21885	COG1609	Transcriptional regulator
BCV49_RS21895	COG2186	Transcriptional regulator
BCV49_RS21900	COG2723	6-phospho-beta-galactosidase activity
BCV49_RS21905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV49_RS21910	COG1609	Transcriptional regulator
BCV49_RS21920	COG0583	DNA-binding transcription factor activity
BCV49_RS21925	COG1794	racemase activity, acting on amino acids and derivatives
BCV49_RS21930	COG1917	Cupin 2, conserved barrel domain protein
BCV49_RS21935	COG1175	transmembrane transport
BCV49_RS21940	COG0395	ABC-type sugar transport system, permease component
BCV49_RS21945	COG3842	ATPase activity
BCV49_RS21980	COG2814	Major facilitator Superfamily
BCV49_RS21985	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS21995	COG0823	Involved in the tonB-independent uptake of proteins
BCV49_RS22005	COG0183	Belongs to the thiolase family
BCV49_RS22020	COG0814	amino acid
BCV49_RS22025	COG0667	Aldo Keto reductase
BCV49_RS22075	COG0697	spore germination
BCV49_RS22080	COG1846	Transcriptional regulator
BCV49_RS22085	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BCV49_RS22095	COG0582	viral genome integration into host DNA
BCV49_RS22100	COG4974	Belongs to the 'phage' integrase family
BCV49_RS22115	COG3539	Fimbrial protein
BCV49_RS22120	COG3121	Chaperone
BCV49_RS22125	COG3188	usher protein
BCV49_RS22130	COG3539	Fimbrial protein
BCV49_RS22135	COG3539	Fimbrial protein
BCV49_RS22140	COG3539	Fimbrial protein
BCV49_RS22150	COG2388	GCN5-related N-acetyl-transferase
BCV49_RS22155	COG3592	Divergent 4Fe-4S mono-cluster
BCV49_RS22170	COG1289	transmembrane transporter activity
BCV49_RS22175	COG1538	Outer membrane efflux protein
BCV49_RS22190	COG1393	Belongs to the ArsC family
BCV49_RS22195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCV49_RS22235	COG0667	Aldo Keto reductase
BCV49_RS22250	COG2814	Major facilitator Superfamily
BCV49_RS22260	COG4942	peptidase
BCV49_RS22285	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCV49_RS22295	COG4974	Belongs to the 'phage' integrase family
BCV49_RS22300	COG0716	FMN binding
BCV49_RS22310	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BCV49_RS22320	COG1272	protein, Hemolysin III
BCV49_RS22330	COG1737	Transcriptional regulator
BCV49_RS22335	COG2723	6-phospho-beta-galactosidase activity
BCV49_RS22355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV49_RS22360	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS22380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV49_RS22385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV49_RS22390	COG0006	proline dipeptidase activity
BCV49_RS22410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCV49_RS22415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCV49_RS22435	COG2968	Membrane
BCV49_RS22450	COG0668	transmembrane transport
BCV49_RS22455	COG0191	fructose-bisphosphate aldolase activity
BCV49_RS22470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCV49_RS22475	COG0501	Belongs to the peptidase M48B family
BCV49_RS22500	COG2814	Major facilitator Superfamily
BCV49_RS22510	COG2356	endonuclease I
BCV49_RS22515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCV49_RS22520	COG0189	ligase activity
BCV49_RS22545	COG2805	Type II/IV secretion system protein
BCV49_RS22550	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCV49_RS22555	COG0762	integral membrane protein
BCV49_RS22570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCV49_RS22585	COG4214	carbohydrate transport
BCV49_RS22595	COG3171	Protein conserved in bacteria
BCV49_RS22605	COG1194	a g-specific adenine glycosylase
BCV49_RS22620	COG2211	Major facilitator Superfamily
BCV49_RS22625	COG1982	Orn Lys Arg decarboxylase major
BCV49_RS22630	COG1811	Na channel or pump
BCV49_RS22665	COG0626	cystathionine gamma-synthase activity
BCV49_RS22690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCV49_RS22695	COG0754	glutathionylspermidine amidase activity
BCV49_RS22710	COG0625	glutathione transferase activity
BCV49_RS22735	COG2211	Major facilitator Superfamily
BCV49_RS22740	COG0848	biopolymer transport protein
BCV49_RS22755	COG0626	cystathionine gamma-synthase activity
BCV49_RS22760	COG0586	Pfam SNARE associated Golgi protein
BCV49_RS22765	COG2207	Transcriptional regulator
BCV49_RS22770	COG1979	alcohol dehydrogenase
BCV49_RS22775	COG0656	L-ascorbic acid biosynthetic process
BCV49_RS22785	COG1032	radical SAM domain protein
BCV49_RS22790	COG2132	Multicopper oxidase
BCV49_RS22795	COG0204	Acyl-transferase
BCV49_RS22800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCV49_RS22805	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BCV49_RS22810	COG3111	PFAM Bacterial OB fold (BOF) protein
BCV49_RS22820	COG0642	Histidine kinase
BCV49_RS22830	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BCV49_RS22840	COG3150	esterase
BCV49_RS22845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BCV49_RS22850	COG3151	Protein conserved in bacteria
BCV49_RS22855	COG0494	nUDIX hydrolase
BCV49_RS22870	COG0754	glutathionylspermidine amidase activity
BCV49_RS22875	COG3384	dioxygenase
BCV49_RS22890	COG2960	long-chain fatty acid transporting porin activity
BCV49_RS22915	COG3025	triphosphatase activity
BCV49_RS22920	COG4991	sh3 domain protein
BCV49_RS22935	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCV49_RS22995	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BCV49_RS23000	COG0358	DNA primase activity
BCV49_RS23005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCV49_RS23030	COG2197	response regulator
BCV49_RS23035	COG2205	protein histidine kinase activity
BCV49_RS23035	COG0784	Response regulator, receiver
BCV49_RS23035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCV49_RS23035	COG2198	Histidine kinase
BCV49_RS23045	COG3247	response to pH
BCV49_RS23115	COG2376	Dihydroxyacetone kinase
BCV49_RS23120	COG1461	Dihydroxyacetone kinase
BCV49_RS23135	COG2375	cellular response to nickel ion
BCV49_RS23145	COG1695	Transcriptional regulator
BCV49_RS23195	COG1902	pentaerythritol trinitrate reductase activity
BCV49_RS23195	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCV49_RS23215	COG1451	nucleotide metabolic process
BCV49_RS23220	COG0673	inositol 2-dehydrogenase activity
BCV49_RS23225	COG0861	Integral membrane protein TerC family
BCV49_RS23240	COG2721	sulfolactate sulfo-lyase activity
BCV49_RS23250	COG2271	Major facilitator Superfamily
BCV49_RS23255	COG2186	Transcriptional regulator
BCV49_RS23260	COG0586	Pfam SNARE associated Golgi protein
BCV49_RS23270	COG1422	Protein of unknown function (DUF1090)
BCV49_RS23275	COG4575	ribosome binding
BCV49_RS23280	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BCV49_RS23290	COG2259	Doxx family
BCV49_RS23295	COG0435	Glutathione S-transferase
BCV49_RS23300	COG3152	Membrane
BCV49_RS23305	COG0583	DNA-binding transcription factor activity
BCV49_RS23310	COG1741	Belongs to the pirin family
BCV49_RS23340	COG1929	Belongs to the glycerate kinase type-1 family
BCV49_RS23345	COG2084	Dehydrogenase
BCV49_RS23355	COG2271	Major facilitator Superfamily
BCV49_RS23365	COG2721	sulfolactate sulfo-lyase activity
BCV49_RS23370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV49_RS23375	COG1349	DNA-binding transcription factor activity
BCV49_RS23390	COG1105	Belongs to the carbohydrate kinase PfkB family
BCV49_RS23395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV49_RS23395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS23395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCV49_RS23400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS23400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS23410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS23415	COG3414	Phosphotransferase system galactitol-specific IIB component
BCV49_RS23420	COG3775	system Galactitol-specific IIC component
BCV49_RS23425	COG1063	alcohol dehydrogenase
BCV49_RS23440	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCV49_RS23460	COG2823	Periplasmic or secreted lipoprotein
BCV49_RS23465	COG0701	Predicted permease
BCV49_RS23470	COG0702	epimerase
BCV49_RS23475	COG0693	protein deglycase activity
BCV49_RS23490	COG3153	acetyltransferase
BCV49_RS23495	COG3154	lipid carrier protein
BCV49_RS23500	COG0826	peptidase U32
BCV49_RS23505	COG0826	peptidase U32
BCV49_RS23510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV49_RS23515	COG0814	amino acid
BCV49_RS23560	COG0195	Participates in both transcription termination and antitermination
BCV49_RS23605	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCV49_RS23620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCV49_RS23630	COG1534	Rna-binding protein
BCV49_RS23640	COG2027	D-alanyl-D-alanine carboxypeptidase
BCV49_RS23650	COG0697	spore germination
BCV49_RS23665	COG0142	geranyltranstransferase activity
BCV49_RS23670	COG3423	Transcriptional regulator
BCV49_RS23680	COG5007	Belongs to the BolA IbaG family
BCV49_RS23685	COG3113	response to antibiotic
BCV49_RS23690	COG2854	intermembrane phospholipid transfer
BCV49_RS23695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCV49_RS23700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BCV49_RS23705	COG1127	ABC transporter
BCV49_RS23710	COG0530	calcium, potassium:sodium antiporter activity
BCV49_RS23720	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BCV49_RS23725	COG3117	lipopolysaccharide transmembrane transporter activity
BCV49_RS23730	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BCV49_RS23735	COG1137	ATPase activity
BCV49_RS23740	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BCV49_RS23745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BCV49_RS23750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS23760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCV49_RS23765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCV49_RS23770	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BCV49_RS23775	COG5002	protein histidine kinase activity
BCV49_RS23775	COG0784	Response regulator, receiver
BCV49_RS23775	COG2198	Histidine kinase
BCV49_RS23780	COG1312	Catalyzes the dehydration of D-mannonate
BCV49_RS23790	COG1063	alcohol dehydrogenase
BCV49_RS23795	COG2271	Major facilitator Superfamily
BCV49_RS23800	COG1242	4 iron, 4 sulfur cluster binding
BCV49_RS23805	COG0069	glutamate synthase activity
BCV49_RS23805	COG0067	glutamate synthase
BCV49_RS23805	COG0070	glutamate synthase
BCV49_RS23810	COG0493	'glutamate synthase
BCV49_RS23820	COG2969	positive regulation of protein catabolic process
BCV49_RS23825	COG0625	glutathione transferase activity
BCV49_RS23840	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BCV49_RS23845	COG3105	Protein conserved in bacteria
BCV49_RS23850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV49_RS23855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV49_RS23880	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BCV49_RS23885	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BCV49_RS23890	COG0471	metal ion transport
BCV49_RS23925	COG2732	(Barnase) inhibitor
BCV49_RS23930	COG1289	transmembrane transporter activity
BCV49_RS23945	COG0583	DNA-binding transcription factor activity
BCV49_RS23950	COG0312	modulator of DNA gyrase
BCV49_RS23955	COG3164	Protein of unknown function
BCV49_RS23960	COG1530	ribonuclease E activity
BCV49_RS23970	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BCV49_RS23975	COG1792	Involved in formation and maintenance of cell shape
BCV49_RS23980	COG1077	Cell shape determining protein MreB Mrl
BCV49_RS23985	COG2199	diguanylate cyclase activity
BCV49_RS23985	COG2200	EAL domain
BCV49_RS24010	COG0511	ligase activity, forming carbon-carbon bonds
BCV49_RS24015	COG0439	Biotin carboxylase
BCV49_RS24020	COG3924	membrane
BCV49_RS24025	COG4145	pantothenate transmembrane transporter activity
BCV49_RS24045	COG1309	transcriptional regulator
BCV49_RS24050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV49_RS24055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV49_RS24090	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCV49_RS24110	COG0551	DNA topoisomerase type I activity
BCV49_RS24120	COG0758	DNA mediated transformation
BCV49_RS24150	COG0789	Transcriptional regulator
BCV49_RS24165	COG0202	RNA polymerase activity
BCV49_RS24185	COG0201	protein transport
BCV49_RS24250	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BCV49_RS24265	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BCV49_RS24290	COG0051	transcription antitermination factor activity, RNA binding
BCV49_RS24345	COG2964	Protein conserved in bacteria
BCV49_RS24350	COG0545	Peptidyl-prolyl cis-trans isomerase
BCV49_RS24360	COG1047	Peptidyl-prolyl cis-trans
BCV49_RS24365	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BCV49_RS24380	COG0488	(ABC) transporter
BCV49_RS24390	COG0429	hydrolase of the alpha beta-hydrolase fold
BCV49_RS24400	COG3954	Phosphoribulokinase
BCV49_RS24405	COG1765	OsmC-like protein
BCV49_RS24415	COG1289	transmembrane transporter activity
BCV49_RS24420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCV49_RS24445	COG0738	Major facilitator superfamily
BCV49_RS24450	COG0402	S-adenosylhomocysteine deaminase activity
BCV49_RS24460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCV49_RS24485	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCV49_RS24490	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BCV49_RS24495	COG3266	domain, Protein
BCV49_RS24510	COG4796	Type ii and iii secretion system protein
BCV49_RS24530	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BCV49_RS24535	COG0494	nUDIX hydrolase
BCV49_RS24545	COG1011	Hydrolase
BCV49_RS24550	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BCV49_RS24580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCV49_RS24585	COG2183	response to ionizing radiation
BCV49_RS24590	COG1918	ferrous iron import across plasma membrane
BCV49_RS24615	COG1040	competence protein
BCV49_RS24625	COG2610	gluconate transmembrane transporter activity
BCV49_RS24630	COG1640	4-alpha-glucanotransferase
BCV49_RS24635	COG0058	SHG alpha-glucan phosphorylase activity
BCV49_RS24645	COG1349	DNA-binding transcription factor activity
BCV49_RS24660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCV49_RS24665	COG0058	SHG alpha-glucan phosphorylase activity
BCV49_RS24690	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCV49_RS24700	COG2610	gluconate transmembrane transporter activity
BCV49_RS24705	COG3265	gluconokinase activity
BCV49_RS24710	COG1609	Transcriptional regulator
BCV49_RS24715	COG1741	Belongs to the pirin family
BCV49_RS24720	COG0673	inositol 2-dehydrogenase activity
BCV49_RS24730	COG1247	-acetyltransferase
BCV49_RS24735	COG0405	Gamma-glutamyltransferase
BCV49_RS24745	COG0584	glycerophosphoryl diester phosphodiesterase
BCV49_RS24795	COG0559	Belongs to the binding-protein-dependent transport system permease family
BCV49_RS24800	COG0683	leucine binding
BCV49_RS24815	COG0683	leucine binding
BCV49_RS24825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCV49_RS24840	COG2177	Part of the ABC transporter FtsEX involved in
BCV49_RS24845	COG2884	Cell division ATP-binding protein ftsE
BCV49_RS24850	COG0552	protein localization to endoplasmic reticulum
BCV49_RS24855	COG0742	ribosomal rna small subunit methyltransferase
BCV49_RS24860	COG3776	membrane
BCV49_RS24870	COG3714	YhhN family
BCV49_RS24885	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BCV49_RS24895	COG0477	Major facilitator Superfamily
BCV49_RS24900	COG0628	permease
BCV49_RS24940	COG3479	Phenolic acid decarboxylase
BCV49_RS24950	COG0747	negative chemotaxis
BCV49_RS24955	COG0601	transmembrane transport
BCV49_RS24960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV49_RS24970	COG1124	(ABC) transporter
BCV49_RS24985	COG2239	Acts as a magnesium transporter
BCV49_RS24990	COG2081	HI0933 family
BCV49_RS24995	COG0306	phosphate transporter
BCV49_RS25005	COG0589	response to stress
BCV49_RS25025	COG0671	phosphoesterase, PA-phosphatase related
BCV49_RS25030	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BCV49_RS25035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCV49_RS25045	COG1454	alcohol dehydrogenase
BCV49_RS25055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCV49_RS25060	COG1028	Short-chain dehydrogenase reductase Sdr
BCV49_RS25065	COG0583	DNA-binding transcription factor activity
BCV49_RS25070	COG1295	ribonuclease BN
BCV49_RS25075	COG0477	Major facilitator Superfamily
BCV49_RS25080	COG2982	Protein involved in outer membrane biogenesis
BCV49_RS25095	COG0612	Peptidase, M16
BCV49_RS25105	COG2199	diguanylate cyclase activity
BCV49_RS25105	COG2200	EAL domain
BCV49_RS25115	COG3118	belongs to the thioredoxin family
BCV49_RS25115	COG0457	Tetratricopeptide repeat
BCV49_RS25120	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BCV49_RS25125	COG1215	transferase activity, transferring glycosyl groups
BCV49_RS25155	COG2194	sulfuric ester hydrolase activity
BCV49_RS25175	COG1215	transferase activity, transferring glycosyl groups
BCV49_RS25185	COG2894	cell division
BCV49_RS25200	COG4608	Belongs to the ABC transporter superfamily
BCV49_RS25205	COG0444	Belongs to the ABC transporter superfamily
BCV49_RS25210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCV49_RS25215	COG0601	transmembrane transport
BCV49_RS25220	COG0747	negative chemotaxis
BCV49_RS25235	COG2801	Transposase and inactivated derivatives
BCV49_RS25255	COG2223	nitrite transmembrane transporter activity
BCV49_RS25260	COG5571	outer membrane autotransporter
BCV49_RS25265	COG2818	Glycosylase
BCV49_RS25270	COG0456	acetyltransferase
BCV49_RS25275	COG0243	molybdopterin cofactor binding
BCV49_RS25280	COG2885	chlorophyll binding
BCV49_RS25290	COG1609	Transcriptional regulator
BCV49_RS25300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV49_RS25320	COG2814	Major facilitator Superfamily
BCV49_RS25325	COG2944	sequence-specific DNA binding
BCV49_RS25330	COG1278	Cold shock
BCV49_RS25335	COG0488	(ABC) transporter
BCV49_RS25360	COG3274	enterobacterial common antigen metabolic process
BCV49_RS25365	COG4682	membrane
BCV49_RS25370	COG4682	membrane
BCV49_RS25385	COG4213	ABC transporter substrate-binding protein
BCV49_RS25395	COG4214	carbohydrate transport
BCV49_RS25400	COG2207	Transcriptional regulator
BCV49_RS25400	COG1609	Transcriptional regulator
BCV49_RS25405	COG2992	FlgJ-related protein
BCV49_RS25410	COG0366	Alpha amylase catalytic
BCV49_RS25415	COG3977	Valine--pyruvate aminotransferase
BCV49_RS25420	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV49_RS25425	COG3276	selenocysteine insertion sequence binding
BCV49_RS25435	COG0625	glutathione transferase activity
BCV49_RS25450	COG3722	fumarate hydratase activity
BCV49_RS25470	COG2186	Transcriptional regulator
BCV49_RS25480	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCV49_RS25500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BCV49_RS25505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCV49_RS25515	COG4942	peptidase
BCV49_RS25520	COG2861	carbohydrate metabolic process
BCV49_RS25525	COG0463	Glycosyl transferase, family 2
BCV49_RS25535	COG0156	8-amino-7-oxononanoate synthase activity
BCV49_RS25550	COG0859	PFAM glycosyl transferase family 9
BCV49_RS25575	COG0859	PFAM glycosyl transferase family 9
BCV49_RS25585	COG0438	transferase activity, transferring glycosyl groups
BCV49_RS25590	COG1216	Glycosyl transferase, family 2
BCV49_RS25595	COG1519	Transferase
BCV49_RS25630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCV49_RS25660	COG0842	Transport permease protein
BCV49_RS25665	COG1131	(ABC) transporter
BCV49_RS25685	COG1561	YicC-like family, N-terminal region
BCV49_RS25695	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BCV49_RS25700	COG2169	Transcriptional regulator
BCV49_RS25700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCV49_RS25710	COG2860	membrane
BCV49_RS25730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCV49_RS25735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCV49_RS25740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCV49_RS25745	COG1494	fructose-1,6-bisphosphatase
BCV49_RS25755	COG3152	Membrane
BCV49_RS25780	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BCV49_RS25785	COG3074	FtsZ-dependent cytokinesis
BCV49_RS25800	COG0786	glutamate:sodium symporter activity
BCV49_RS25810	COG2233	PERMEase
BCV49_RS25815	COG2982	Protein involved in outer membrane biogenesis
BCV49_RS25820	COG1263	PTS System
BCV49_RS25820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV49_RS25825	COG1486	melibiose metabolic process
BCV49_RS25835	COG1501	Belongs to the glycosyl hydrolase 31 family
BCV49_RS25840	COG2211	Major facilitator Superfamily
BCV49_RS25850	COG0582	viral genome integration into host DNA
BCV49_RS25885	COG1064	alcohol dehydrogenase
BCV49_RS25895	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BCV49_RS25910	COG1464	Belongs to the NlpA lipoprotein family
BCV49_RS25935	COG0583	DNA-binding transcription factor activity
BCV49_RS25975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV49_RS25985	COG2814	Major facilitator Superfamily
BCV49_RS25995	COG1263	PTS System
BCV49_RS25995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCV49_RS26000	COG0697	spore germination
BCV49_RS26015	COG2828	Protein conserved in bacteria
BCV49_RS26020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BCV49_RS26025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCV49_RS26030	COG0583	DNA-binding transcription factor activity
BCV49_RS26035	COG3384	dioxygenase
BCV49_RS26045	COG1609	Transcriptional regulator
BCV49_RS26055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV49_RS26055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCV49_RS26060	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCV49_RS26065	COG4580	involved in the transport of maltose and maltodextrins
BCV49_RS26090	COG2188	Transcriptional regulator
BCV49_RS26130	COG2271	Major facilitator Superfamily
BCV49_RS26140	COG2197	response regulator
BCV49_RS26145	COG0440	acetolactate synthase activity
BCV49_RS26150	COG0028	Belongs to the TPP enzyme family
BCV49_RS26170	COG2814	Major facilitator Superfamily
BCV49_RS26175	COG0583	DNA-binding transcription factor activity
BCV49_RS26185	COG2610	gluconate transmembrane transporter activity
BCV49_RS26205	COG2149	membrane
BCV49_RS26220	COG2188	Transcriptional regulator
BCV49_RS26230	COG3645	SOS response
BCV49_RS26245	COG5645	(Lipo)protein
BCV49_RS26250	COG0823	Involved in the tonB-independent uptake of proteins
BCV49_RS26255	COG2271	Major facilitator Superfamily
BCV49_RS26265	COG0800	Aldolase
BCV49_RS26270	COG3734	2-keto-3-deoxy-galactonokinase
BCV49_RS26275	COG2186	Transcriptional regulator
BCV49_RS26290	COG0561	phosphatase activity
BCV49_RS26295	COG0187	DNA topoisomerase II activity
BCV49_RS26325	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BCV49_RS26355	COG2091	lysine biosynthetic process via aminoadipic acid
BCV49_RS26360	COG0431	NADPH-dependent FMN reductase
BCV49_RS26365	COG2252	PERMEase
BCV49_RS26375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCV49_RS26380	COG0363	glucosamine-6-phosphate deaminase activity
BCV49_RS26385	COG2382	esterase
BCV49_RS26400	COG0704	Plays a role in the regulation of phosphate uptake
BCV49_RS26405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCV49_RS26410	COG0581	inorganic phosphate transmembrane transporter activity
BCV49_RS26415	COG0573	inorganic phosphate transmembrane transporter activity
BCV49_RS26420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCV49_RS26490	COG3312	ion transport
BCV49_RS26740	COG0437	4 iron, 4 sulfur cluster binding
BCV49_RS26920	COG1575	Belongs to the MenA family. Type 1 subfamily
BCV49_RS26930	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BCV49_RS27350	COG3072	Adenylate cyclase