locus-tag	class	description
C2L62_RS00020	COG0187	DNA topoisomerase II activity
C2L62_RS00025	COG0561	phosphatase activity
C2L62_RS00040	COG2186	Transcriptional regulator
C2L62_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
C2L62_RS00050	COG0800	Aldolase
C2L62_RS00080	COG2271	Major facilitator Superfamily
C2L62_RS00085	COG0823	Involved in the tonB-independent uptake of proteins
C2L62_RS00090	COG5645	(Lipo)protein
C2L62_RS00105	COG3645	SOS response
C2L62_RS00115	COG2188	Transcriptional regulator
C2L62_RS00130	COG2149	membrane
C2L62_RS00150	COG2610	gluconate transmembrane transporter activity
C2L62_RS00155	COG0583	DNA-binding transcription factor activity
C2L62_RS00160	COG2814	Major facilitator Superfamily
C2L62_RS00185	COG0028	Belongs to the TPP enzyme family
C2L62_RS00190	COG0440	acetolactate synthase activity
C2L62_RS00195	COG2197	response regulator
C2L62_RS00205	COG2271	Major facilitator Superfamily
C2L62_RS00250	COG2188	Transcriptional regulator
C2L62_RS00285	COG4580	involved in the transport of maltose and maltodextrins
C2L62_RS00290	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2L62_RS00295	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS00295	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS00305	COG1609	Transcriptional regulator
C2L62_RS00315	COG3384	dioxygenase
C2L62_RS00320	COG0583	DNA-binding transcription factor activity
C2L62_RS00325	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C2L62_RS00330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C2L62_RS00335	COG2828	Protein conserved in bacteria
C2L62_RS00350	COG0697	spore germination
C2L62_RS00355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2L62_RS00355	COG1263	PTS System
C2L62_RS00365	COG2814	Major facilitator Superfamily
C2L62_RS00375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2L62_RS00410	COG0583	DNA-binding transcription factor activity
C2L62_RS00435	COG1464	Belongs to the NlpA lipoprotein family
C2L62_RS00450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C2L62_RS00460	COG1064	alcohol dehydrogenase
C2L62_RS00495	COG2211	Major facilitator Superfamily
C2L62_RS00500	COG1501	Belongs to the glycosyl hydrolase 31 family
C2L62_RS00510	COG1486	melibiose metabolic process
C2L62_RS00515	COG1263	PTS System
C2L62_RS00515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2L62_RS00520	COG2982	Protein involved in outer membrane biogenesis
C2L62_RS00525	COG2233	PERMEase
C2L62_RS00530	COG0786	glutamate:sodium symporter activity
C2L62_RS00550	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C2L62_RS00575	COG3152	Membrane
C2L62_RS00585	COG1494	fructose-1,6-bisphosphatase
C2L62_RS00590	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C2L62_RS00595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2L62_RS00600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C2L62_RS00620	COG2860	membrane
C2L62_RS00630	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C2L62_RS00630	COG2169	Transcriptional regulator
C2L62_RS00635	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C2L62_RS00640	COG1561	YicC-like family, N-terminal region
C2L62_RS00650	COG3039	Transposase
C2L62_RS00665	COG1131	(ABC) transporter
C2L62_RS00670	COG0842	Transport permease protein
C2L62_RS00695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C2L62_RS00730	COG1519	Transferase
C2L62_RS00735	COG1216	Glycosyl transferase, family 2
C2L62_RS00740	COG0438	transferase activity, transferring glycosyl groups
C2L62_RS00750	COG0859	PFAM glycosyl transferase family 9
C2L62_RS00775	COG0859	PFAM glycosyl transferase family 9
C2L62_RS00790	COG0156	8-amino-7-oxononanoate synthase activity
C2L62_RS00800	COG0463	Glycosyl transferase, family 2
C2L62_RS00805	COG2861	carbohydrate metabolic process
C2L62_RS00810	COG4942	peptidase
C2L62_RS00820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2L62_RS00825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C2L62_RS00845	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C2L62_RS00855	COG2186	Transcriptional regulator
C2L62_RS00875	COG3722	fumarate hydratase activity
C2L62_RS00895	COG1566	PFAM secretion protein HlyD family protein
C2L62_RS00900	COG0625	glutathione transferase activity
C2L62_RS00910	COG3276	selenocysteine insertion sequence binding
C2L62_RS00915	COG1414	Transcriptional regulator
C2L62_RS00920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2L62_RS00925	COG3977	Valine--pyruvate aminotransferase
C2L62_RS00930	COG0366	Alpha amylase catalytic
C2L62_RS00935	COG2992	FlgJ-related protein
C2L62_RS00940	COG2207	Transcriptional regulator
C2L62_RS00940	COG1609	Transcriptional regulator
C2L62_RS00945	COG4214	carbohydrate transport
C2L62_RS00955	COG4213	ABC transporter substrate-binding protein
C2L62_RS00975	COG4682	membrane
C2L62_RS00980	COG4682	membrane
C2L62_RS00985	COG3274	enterobacterial common antigen metabolic process
C2L62_RS01025	COG1278	Cold shock
C2L62_RS01030	COG2944	sequence-specific DNA binding
C2L62_RS01035	COG2814	Major facilitator Superfamily
C2L62_RS01060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2L62_RS01070	COG1609	Transcriptional regulator
C2L62_RS01075	COG2885	chlorophyll binding
C2L62_RS01080	COG0243	molybdopterin cofactor binding
C2L62_RS01085	COG0456	acetyltransferase
C2L62_RS01090	COG2818	Glycosylase
C2L62_RS01095	COG5571	outer membrane autotransporter
C2L62_RS01100	COG2223	nitrite transmembrane transporter activity
C2L62_RS01130	COG0747	negative chemotaxis
C2L62_RS01135	COG0601	transmembrane transport
C2L62_RS01140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2L62_RS01145	COG0444	Belongs to the ABC transporter superfamily
C2L62_RS01150	COG4608	Belongs to the ABC transporter superfamily
C2L62_RS01175	COG1215	transferase activity, transferring glycosyl groups
C2L62_RS01180	COG0457	Tetratricopeptide repeat
C2L62_RS01195	COG2194	sulfuric ester hydrolase activity
C2L62_RS01225	COG1215	transferase activity, transferring glycosyl groups
C2L62_RS01230	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C2L62_RS01235	COG0457	Tetratricopeptide repeat
C2L62_RS01235	COG3118	belongs to the thioredoxin family
C2L62_RS01240	COG2199	diguanylate cyclase activity
C2L62_RS01240	COG2200	EAL domain
C2L62_RS01250	COG0612	Peptidase, M16
C2L62_RS01265	COG2982	Protein involved in outer membrane biogenesis
C2L62_RS01270	COG0477	Major facilitator Superfamily
C2L62_RS01275	COG1295	ribonuclease BN
C2L62_RS01280	COG0583	DNA-binding transcription factor activity
C2L62_RS01285	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS01290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2L62_RS01300	COG1454	alcohol dehydrogenase
C2L62_RS01310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2L62_RS01315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C2L62_RS01320	COG0671	phosphoesterase, PA-phosphatase related
C2L62_RS01340	COG0589	response to stress
C2L62_RS01350	COG0306	phosphate transporter
C2L62_RS01355	COG2081	HI0933 family
C2L62_RS01360	COG2239	Acts as a magnesium transporter
C2L62_RS01370	COG1124	(ABC) transporter
C2L62_RS01380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2L62_RS01385	COG0601	transmembrane transport
C2L62_RS01390	COG0747	negative chemotaxis
C2L62_RS01405	COG3479	Phenolic acid decarboxylase
C2L62_RS01445	COG0628	permease
C2L62_RS01450	COG0477	Major facilitator Superfamily
C2L62_RS01460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C2L62_RS01475	COG3714	YhhN family
C2L62_RS01485	COG3776	membrane
C2L62_RS01490	COG0742	ribosomal rna small subunit methyltransferase
C2L62_RS01495	COG0552	protein localization to endoplasmic reticulum
C2L62_RS01500	COG2884	Cell division ATP-binding protein ftsE
C2L62_RS01505	COG2177	Part of the ABC transporter FtsEX involved in
C2L62_RS01520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C2L62_RS01530	COG0683	leucine binding
C2L62_RS01545	COG0683	leucine binding
C2L62_RS01550	COG0559	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS01600	COG0584	glycerophosphoryl diester phosphodiesterase
C2L62_RS01610	COG0405	Gamma-glutamyltransferase
C2L62_RS01615	COG1247	-acetyltransferase
C2L62_RS01625	COG0673	inositol 2-dehydrogenase activity
C2L62_RS01630	COG1741	Belongs to the pirin family
C2L62_RS01635	COG1609	Transcriptional regulator
C2L62_RS01640	COG3265	gluconokinase activity
C2L62_RS01645	COG2610	gluconate transmembrane transporter activity
C2L62_RS01655	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C2L62_RS01680	COG0058	SHG alpha-glucan phosphorylase activity
C2L62_RS01695	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C2L62_RS01710	COG1349	DNA-binding transcription factor activity
C2L62_RS01725	COG0058	SHG alpha-glucan phosphorylase activity
C2L62_RS01730	COG1640	4-alpha-glucanotransferase
C2L62_RS01735	COG2610	gluconate transmembrane transporter activity
C2L62_RS01745	COG1040	competence protein
C2L62_RS01770	COG1918	ferrous iron import across plasma membrane
C2L62_RS01775	COG2183	response to ionizing radiation
C2L62_RS01780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C2L62_RS01805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C2L62_RS01810	COG1011	Hydrolase
C2L62_RS01820	COG0494	nUDIX hydrolase
C2L62_RS01825	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C2L62_RS01850	COG4796	Type ii and iii secretion system protein
C2L62_RS01870	COG3266	domain, Protein
C2L62_RS01875	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C2L62_RS01880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C2L62_RS01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C2L62_RS01910	COG0402	S-adenosylhomocysteine deaminase activity
C2L62_RS01915	COG0738	Major facilitator superfamily
C2L62_RS01940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C2L62_RS01945	COG1289	transmembrane transporter activity
C2L62_RS01955	COG1765	OsmC-like protein
C2L62_RS01960	COG3954	Phosphoribulokinase
C2L62_RS01970	COG0429	hydrolase of the alpha beta-hydrolase fold
C2L62_RS01980	COG0488	(ABC) transporter
C2L62_RS01995	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C2L62_RS02000	COG1047	Peptidyl-prolyl cis-trans
C2L62_RS02010	COG0545	Peptidyl-prolyl cis-trans isomerase
C2L62_RS02015	COG2964	Protein conserved in bacteria
C2L62_RS02070	COG0051	transcription antitermination factor activity, RNA binding
C2L62_RS02095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C2L62_RS02110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C2L62_RS02175	COG0201	protein transport
C2L62_RS02200	COG0202	RNA polymerase activity
C2L62_RS02215	COG0789	Transcriptional regulator
C2L62_RS02220	COG3036	rescue of stalled ribosome
C2L62_RS02250	COG0758	DNA mediated transformation
C2L62_RS02260	COG0551	DNA topoisomerase type I activity
C2L62_RS02280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C2L62_RS02315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2L62_RS02320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2L62_RS02325	COG1309	transcriptional regulator
C2L62_RS02330	COG0582	viral genome integration into host DNA
C2L62_RS02345	COG3561	AntA/AntB antirepressor
C2L62_RS02435	COG4626	Terminase
C2L62_RS02435	COG1802	Transcriptional regulator
C2L62_RS02465	COG4145	pantothenate transmembrane transporter activity
C2L62_RS02470	COG3924	membrane
C2L62_RS02475	COG0439	Biotin carboxylase
C2L62_RS02480	COG0511	ligase activity, forming carbon-carbon bonds
C2L62_RS02505	COG2199	diguanylate cyclase activity
C2L62_RS02505	COG2200	EAL domain
C2L62_RS02510	COG1077	Cell shape determining protein MreB Mrl
C2L62_RS02515	COG1792	Involved in formation and maintenance of cell shape
C2L62_RS02520	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C2L62_RS02530	COG1530	ribonuclease E activity
C2L62_RS02535	COG3164	Protein of unknown function
C2L62_RS02540	COG0312	modulator of DNA gyrase
C2L62_RS02545	COG0583	DNA-binding transcription factor activity
C2L62_RS02560	COG1289	transmembrane transporter activity
C2L62_RS02565	COG2732	(Barnase) inhibitor
C2L62_RS02590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2L62_RS02595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2L62_RS02600	COG3105	Protein conserved in bacteria
C2L62_RS02605	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C2L62_RS02625	COG0625	glutathione transferase activity
C2L62_RS02630	COG2969	positive regulation of protein catabolic process
C2L62_RS02640	COG0493	'glutamate synthase
C2L62_RS02645	COG0067	glutamate synthase
C2L62_RS02645	COG0069	glutamate synthase activity
C2L62_RS02645	COG0070	glutamate synthase
C2L62_RS02650	COG1242	4 iron, 4 sulfur cluster binding
C2L62_RS02655	COG2271	Major facilitator Superfamily
C2L62_RS02660	COG1063	alcohol dehydrogenase
C2L62_RS02665	COG1312	Catalyzes the dehydration of D-mannonate
C2L62_RS02670	COG0784	Response regulator, receiver
C2L62_RS02670	COG2198	Histidine kinase
C2L62_RS02670	COG5002	protein histidine kinase activity
C2L62_RS02675	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C2L62_RS02680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C2L62_RS02685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS02695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS02700	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C2L62_RS02705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C2L62_RS02710	COG1137	ATPase activity
C2L62_RS02715	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C2L62_RS02720	COG3117	lipopolysaccharide transmembrane transporter activity
C2L62_RS02725	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C2L62_RS02735	COG0530	calcium, potassium:sodium antiporter activity
C2L62_RS02745	COG1127	ABC transporter
C2L62_RS02750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C2L62_RS02755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C2L62_RS02760	COG2854	intermembrane phospholipid transfer
C2L62_RS02765	COG3113	response to antibiotic
C2L62_RS02770	COG5007	Belongs to the BolA IbaG family
C2L62_RS02780	COG3423	Transcriptional regulator
C2L62_RS02785	COG0142	geranyltranstransferase activity
C2L62_RS02800	COG0697	spore germination
C2L62_RS02810	COG2027	D-alanyl-D-alanine carboxypeptidase
C2L62_RS02820	COG1534	Rna-binding protein
C2L62_RS02830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C2L62_RS02835	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C2L62_RS02845	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C2L62_RS02885	COG0195	Participates in both transcription termination and antitermination
C2L62_RS02935	COG0814	amino acid
C2L62_RS02940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2L62_RS02945	COG0826	peptidase U32
C2L62_RS02950	COG0826	peptidase U32
C2L62_RS02955	COG3154	lipid carrier protein
C2L62_RS02960	COG3153	acetyltransferase
C2L62_RS02975	COG0693	protein deglycase activity
C2L62_RS02980	COG0702	epimerase
C2L62_RS02985	COG0701	Predicted permease
C2L62_RS02990	COG2823	Periplasmic or secreted lipoprotein
C2L62_RS03010	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C2L62_RS03025	COG1063	alcohol dehydrogenase
C2L62_RS03030	COG3775	system Galactitol-specific IIC component
C2L62_RS03035	COG3414	Phosphotransferase system galactitol-specific IIB component
C2L62_RS03040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS03050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS03050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS03055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2L62_RS03055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS03055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2L62_RS03060	COG1105	Belongs to the carbohydrate kinase PfkB family
C2L62_RS03070	COG1349	DNA-binding transcription factor activity
C2L62_RS03075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2L62_RS03080	COG2721	sulfolactate sulfo-lyase activity
C2L62_RS03090	COG2271	Major facilitator Superfamily
C2L62_RS03100	COG2084	Dehydrogenase
C2L62_RS03105	COG1929	Belongs to the glycerate kinase type-1 family
C2L62_RS03125	COG1741	Belongs to the pirin family
C2L62_RS03130	COG0583	DNA-binding transcription factor activity
C2L62_RS03135	COG3152	Membrane
C2L62_RS03140	COG0435	Glutathione S-transferase
C2L62_RS03145	COG2259	Doxx family
C2L62_RS03155	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C2L62_RS03160	COG4575	ribosome binding
C2L62_RS03165	COG1422	Protein of unknown function (DUF1090)
C2L62_RS03175	COG0586	Pfam SNARE associated Golgi protein
C2L62_RS03180	COG2186	Transcriptional regulator
C2L62_RS03185	COG2271	Major facilitator Superfamily
C2L62_RS03195	COG2721	sulfolactate sulfo-lyase activity
C2L62_RS03210	COG0861	Integral membrane protein TerC family
C2L62_RS03215	COG0673	inositol 2-dehydrogenase activity
C2L62_RS03220	COG1451	nucleotide metabolic process
C2L62_RS03240	COG0446	pyridine nucleotide-disulphide oxidoreductase
C2L62_RS03240	COG1902	pentaerythritol trinitrate reductase activity
C2L62_RS03290	COG1695	Transcriptional regulator
C2L62_RS03295	COG2375	cellular response to nickel ion
C2L62_RS03310	COG1461	Dihydroxyacetone kinase
C2L62_RS03315	COG2376	Dihydroxyacetone kinase
C2L62_RS03395	COG3247	response to pH
C2L62_RS03405	COG0784	Response regulator, receiver
C2L62_RS03405	COG2198	Histidine kinase
C2L62_RS03405	COG2205	protein histidine kinase activity
C2L62_RS03405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2L62_RS03410	COG2197	response regulator
C2L62_RS03435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C2L62_RS03440	COG0358	DNA primase activity
C2L62_RS03445	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C2L62_RS03510	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C2L62_RS03525	COG4991	sh3 domain protein
C2L62_RS03530	COG3025	triphosphatase activity
C2L62_RS03550	COG2960	long-chain fatty acid transporting porin activity
C2L62_RS03565	COG3384	dioxygenase
C2L62_RS03570	COG0754	glutathionylspermidine amidase activity
C2L62_RS03585	COG0494	nUDIX hydrolase
C2L62_RS03590	COG3151	Protein conserved in bacteria
C2L62_RS03595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C2L62_RS03600	COG3150	esterase
C2L62_RS03610	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C2L62_RS03615	COG2249	NAD(P)H dehydrogenase (quinone) activity
C2L62_RS03620	COG0642	Histidine kinase
C2L62_RS03630	COG3111	PFAM Bacterial OB fold (BOF) protein
C2L62_RS03635	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C2L62_RS03640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C2L62_RS03645	COG0204	Acyl-transferase
C2L62_RS03650	COG2132	Multicopper oxidase
C2L62_RS03655	COG1032	radical SAM domain protein
C2L62_RS03665	COG0656	L-ascorbic acid biosynthetic process
C2L62_RS03670	COG1979	alcohol dehydrogenase
C2L62_RS03675	COG2207	Transcriptional regulator
C2L62_RS03680	COG0586	Pfam SNARE associated Golgi protein
C2L62_RS03685	COG0626	cystathionine gamma-synthase activity
C2L62_RS03695	COG0848	biopolymer transport protein
C2L62_RS03700	COG2211	Major facilitator Superfamily
C2L62_RS03725	COG0625	glutathione transferase activity
C2L62_RS03735	COG0754	glutathionylspermidine amidase activity
C2L62_RS03740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2L62_RS03760	COG0583	DNA-binding transcription factor activity
C2L62_RS03765	COG0626	cystathionine gamma-synthase activity
C2L62_RS04030	COG3423	Transcriptional regulator
C2L62_RS04040	COG1278	Cold shock
C2L62_RS04045	COG3423	Transcriptional regulator
C2L62_RS04120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C2L62_RS04130	COG1811	Na channel or pump
C2L62_RS04140	COG1982	Orn Lys Arg decarboxylase major
C2L62_RS04145	COG2211	Major facilitator Superfamily
C2L62_RS04160	COG1194	a g-specific adenine glycosylase
C2L62_RS04170	COG3171	Protein conserved in bacteria
C2L62_RS04180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C2L62_RS04195	COG0762	integral membrane protein
C2L62_RS04200	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C2L62_RS04205	COG2805	Type II/IV secretion system protein
C2L62_RS04225	COG0189	ligase activity
C2L62_RS04230	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C2L62_RS04255	COG2814	Major facilitator Superfamily
C2L62_RS04295	COG2146	nitrite reductase [NAD(P)H] activity
C2L62_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS04315	COG1414	Transcriptional regulator
C2L62_RS04345	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS04350	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
C2L62_RS04380	COG0501	Belongs to the peptidase M48B family
C2L62_RS04385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C2L62_RS04400	COG0191	fructose-bisphosphate aldolase activity
C2L62_RS04405	COG0668	transmembrane transport
C2L62_RS04415	COG2968	Membrane
C2L62_RS04430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C2L62_RS04435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C2L62_RS04455	COG0006	proline dipeptidase activity
C2L62_RS04460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C2L62_RS04465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C2L62_RS04485	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS04490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2L62_RS04510	COG2723	6-phospho-beta-galactosidase activity
C2L62_RS04515	COG1737	Transcriptional regulator
C2L62_RS04525	COG1272	protein, Hemolysin III
C2L62_RS04535	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C2L62_RS04545	COG0716	FMN binding
C2L62_RS04550	COG4974	Belongs to the 'phage' integrase family
C2L62_RS04560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C2L62_RS04580	COG4942	peptidase
C2L62_RS04590	COG2814	Major facilitator Superfamily
C2L62_RS04605	COG0667	Aldo Keto reductase
C2L62_RS04640	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C2L62_RS04645	COG1393	Belongs to the ArsC family
C2L62_RS04660	COG1538	Outer membrane efflux protein
C2L62_RS04665	COG1289	transmembrane transporter activity
C2L62_RS04680	COG3592	Divergent 4Fe-4S mono-cluster
C2L62_RS04685	COG2388	GCN5-related N-acetyl-transferase
C2L62_RS04695	COG3539	Fimbrial protein
C2L62_RS04700	COG3539	Fimbrial protein
C2L62_RS04705	COG3539	Fimbrial protein
C2L62_RS04710	COG3188	usher protein
C2L62_RS04715	COG3121	Chaperone
C2L62_RS04720	COG3539	Fimbrial protein
C2L62_RS04730	COG4974	Belongs to the 'phage' integrase family
C2L62_RS04735	COG0582	viral genome integration into host DNA
C2L62_RS04745	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C2L62_RS04750	COG1846	Transcriptional regulator
C2L62_RS04755	COG0697	spore germination
C2L62_RS04810	COG0667	Aldo Keto reductase
C2L62_RS04815	COG0814	amino acid
C2L62_RS04830	COG0183	Belongs to the thiolase family
C2L62_RS04840	COG0823	Involved in the tonB-independent uptake of proteins
C2L62_RS04845	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS04850	COG2814	Major facilitator Superfamily
C2L62_RS04880	COG3842	ATPase activity
C2L62_RS04885	COG0395	ABC-type sugar transport system, permease component
C2L62_RS04890	COG1175	transmembrane transport
C2L62_RS04895	COG1917	Cupin 2, conserved barrel domain protein
C2L62_RS04900	COG1794	racemase activity, acting on amino acids and derivatives
C2L62_RS04905	COG0583	DNA-binding transcription factor activity
C2L62_RS04915	COG1609	Transcriptional regulator
C2L62_RS04920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS04925	COG2723	6-phospho-beta-galactosidase activity
C2L62_RS04930	COG2186	Transcriptional regulator
C2L62_RS04940	COG1609	Transcriptional regulator
C2L62_RS04965	COG0667	Aldo Keto reductase
C2L62_RS04975	COG0861	Integral membrane protein TerC family
C2L62_RS05010	COG2165	general secretion pathway protein
C2L62_RS05015	COG4795	General secretion pathway protein
C2L62_RS05025	COG4967	type IV pilus modification protein PilV
C2L62_RS05030	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C2L62_RS05035	COG1025	Belongs to the peptidase M16 family
C2L62_RS05040	COG1074	ATP-dependent DNA helicase activity
C2L62_RS05045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C2L62_RS05055	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C2L62_RS05055	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C2L62_RS05060	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2L62_RS05065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C2L62_RS05095	COG4656	Part of a membrane complex involved in electron transport
C2L62_RS05100	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS05100	COG1454	alcohol dehydrogenase
C2L62_RS05130	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C2L62_RS05295	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C2L62_RS05300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C2L62_RS05305	COG2166	iron-sulfur cluster assembly
C2L62_RS05310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C2L62_RS05320	COG0583	DNA-binding transcription factor activity
C2L62_RS05325	COG2363	Small membrane protein
C2L62_RS05335	COG1349	DNA-binding transcription factor activity
C2L62_RS05355	COG0738	Major facilitator superfamily
C2L62_RS05360	COG0235	Class ii aldolase
C2L62_RS05365	COG1454	alcohol dehydrogenase
C2L62_RS05380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2L62_RS05395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C2L62_RS05400	COG2011	ABC-type metal ion transport system permease component
C2L62_RS05405	COG1464	Belongs to the NlpA lipoprotein family
C2L62_RS05415	COG0477	Major facilitator Superfamily
C2L62_RS05425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C2L62_RS05430	COG1760	l-serine dehydratase
C2L62_RS05435	COG0814	amino acid
C2L62_RS05440	COG1611	Belongs to the LOG family
C2L62_RS05455	COG3098	single-species biofilm formation
C2L62_RS05460	COG0564	pseudouridine synthase activity
C2L62_RS05465	COG0716	FMN binding
C2L62_RS05470	COG2271	Major facilitator Superfamily
C2L62_RS05475	COG4948	Mandelate Racemase Muconate Lactonizing
C2L62_RS05480	COG4948	Mandelate Racemase Muconate Lactonizing
C2L62_RS05485	COG1929	Belongs to the glycerate kinase type-1 family
C2L62_RS05495	COG3437	response regulator, receiver
C2L62_RS05495	COG2205	protein histidine kinase activity
C2L62_RS05495	COG3850	Histidine kinase
C2L62_RS05495	COG4999	Histidine kinase
C2L62_RS05505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C2L62_RS05510	COG3956	TIGRFAM MazG family protein
C2L62_RS05530	COG0602	queuosine metabolic process
C2L62_RS05535	COG0720	synthase
C2L62_RS05555	COG2234	aminopeptidase activity
C2L62_RS05615	COG4942	peptidase
C2L62_RS05615	COG1388	LysM domain
C2L62_RS05620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C2L62_RS05645	COG0163	prenyltransferase activity
C2L62_RS05650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C2L62_RS05695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2L62_RS05700	COG4558	Periplasmic binding protein
C2L62_RS05705	COG3720	iron ion transport
C2L62_RS05725	COG0679	Auxin Efflux Carrier
C2L62_RS05740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2L62_RS05745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2L62_RS05750	COG1121	(ABC) transporter
C2L62_RS05755	COG0803	Belongs to the bacterial solute-binding protein 9 family
C2L62_RS05760	COG1609	Transcriptional regulator
C2L62_RS05765	COG1940	carbohydrate kinase activity
C2L62_RS05770	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2L62_RS05775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS05780	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS05785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS05795	COG4580	involved in the transport of maltose and maltodextrins
C2L62_RS05805	COG2723	6-phospho-beta-galactosidase activity
C2L62_RS05815	COG0309	Hydrogenase expression formation protein (HypE)
C2L62_RS05820	COG0409	Hydrogenase expression formation protein
C2L62_RS05825	COG0298	carbon dioxide binding
C2L62_RS05830	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C2L62_RS05850	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2L62_RS05855	COG0651	ATP synthesis coupled electron transport
C2L62_RS05860	COG0650	Formate hydrogenlyase subunit 4
C2L62_RS05865	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C2L62_RS05865	COG3261	NADH dehydrogenase
C2L62_RS05870	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C2L62_RS05875	COG3260	NADH ubiquinone oxidoreductase 20
C2L62_RS05885	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C2L62_RS05895	COG2723	6-phospho-beta-galactosidase activity
C2L62_RS05900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2L62_RS05900	COG1263	PTS System
C2L62_RS05905	COG1609	Transcriptional regulator
C2L62_RS05910	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2L62_RS05915	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C2L62_RS05920	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
C2L62_RS05950	COG1349	DNA-binding transcription factor activity
C2L62_RS05955	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS05960	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS05970	COG3732	PTS system glucitol sorbitol-specific
C2L62_RS05975	COG3730	PTS system glucitol sorbitol-specific
C2L62_RS05980	COG2951	lytic endotransglycosylase activity
C2L62_RS05990	COG1121	(ABC) transporter
C2L62_RS05995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2L62_RS06000	COG0803	Belongs to the bacterial solute-binding protein 9 family
C2L62_RS06005	COG1546	Belongs to the CinA family
C2L62_RS06030	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C2L62_RS06060	COG2823	Periplasmic or secreted lipoprotein
C2L62_RS06065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2L62_RS06070	COG1238	metal cluster binding
C2L62_RS06090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C2L62_RS06095	COG2814	Major facilitator Superfamily
C2L62_RS06100	COG1566	PFAM secretion protein HlyD family protein
C2L62_RS06105	COG1846	Transcriptional regulator
C2L62_RS06115	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C2L62_RS06125	COG4176	ABC-type proline glycine betaine transport system permease component
C2L62_RS06140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C2L62_RS06150	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C2L62_RS06155	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2L62_RS06160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2L62_RS06165	COG4575	ribosome binding
C2L62_RS06205	COG2916	Histone family protein nucleoid-structuring protein H-NS
C2L62_RS06220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2L62_RS06225	COG0640	Transcriptional regulator
C2L62_RS06235	COG0583	DNA-binding transcription factor activity
C2L62_RS06240	COG3284	Transcriptional regulator
C2L62_RS06250	COG3539	Fimbrial protein
C2L62_RS06255	COG3121	Chaperone
C2L62_RS06275	COG3188	usher protein
C2L62_RS06285	COG3539	Fimbrial protein
C2L62_RS06290	COG2197	response regulator
C2L62_RS06305	COG4974	Belongs to the 'phage' integrase family
C2L62_RS06340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2L62_RS06360	COG3344	reverse transcriptase
C2L62_RS06395	COG4695	Portal protein
C2L62_RS06560	COG2867	negative regulation of translational initiation
C2L62_RS06575	COG0497	DNA recombination
C2L62_RS06595	COG4536	flavin adenine dinucleotide binding
C2L62_RS06600	COG4137	Cytochrome C assembly protein
C2L62_RS06605	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C2L62_RS06640	COG2885	chlorophyll binding
C2L62_RS06645	COG2199	diguanylate cyclase activity
C2L62_RS06655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C2L62_RS06660	COG0287	Prephenate dehydrogenase
C2L62_RS06660	COG1605	Chorismate mutase
C2L62_RS06670	COG1605	Chorismate mutase
C2L62_RS06670	COG0077	Prephenate dehydratase
C2L62_RS06680	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C2L62_RS06685	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2L62_RS06700	COG0542	response to heat
C2L62_RS06725	COG0477	Major facilitator Superfamily
C2L62_RS06730	COG5544	Lipoprotein
C2L62_RS06735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2L62_RS06745	COG3148	PFAM DTW domain containing protein
C2L62_RS06750	COG3118	belongs to the thioredoxin family
C2L62_RS06755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2L62_RS06770	COG0513	Belongs to the DEAD box helicase family
C2L62_RS06780	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C2L62_RS06795	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C2L62_RS06800	COG3026	antisigma factor binding
C2L62_RS06805	COG3086	response to oxidative stress
C2L62_RS06815	COG0681	Belongs to the peptidase S26 family
C2L62_RS06835	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C2L62_RS06845	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2L62_RS06850	COG1737	Transcriptional regulator
C2L62_RS06855	COG0560	Phosphoserine phosphatase
C2L62_RS06870	COG0047	phosphoribosylformylglycinamidine synthase activity
C2L62_RS06870	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C2L62_RS06875	COG2205	protein histidine kinase activity
C2L62_RS06880	COG3170	Tfp pilus assembly protein FimV
C2L62_RS06885	COG2204	response regulator
C2L62_RS06890	COG0347	Belongs to the P(II) protein family
C2L62_RS06895	COG1017	nitric oxide dioxygenase activity
C2L62_RS06895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2L62_RS06905	COG2259	Doxx family
C2L62_RS06910	COG1940	carbohydrate kinase activity
C2L62_RS06915	COG0457	Tetratricopeptide repeat
C2L62_RS06920	COG0477	Major facilitator Superfamily
C2L62_RS06920	COG2814	Major facilitator Superfamily
C2L62_RS06925	COG2017	converts alpha-aldose to the beta-anomer
C2L62_RS06930	COG2814	Major facilitator Superfamily
C2L62_RS06935	COG3711	transcriptional antiterminator
C2L62_RS06940	COG3683	transport system, periplasmic component
C2L62_RS06945	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C2L62_RS06975	COG0822	iron-sulfur transferase activity
C2L62_RS06995	COG0633	Ferredoxin
C2L62_RS07000	COG2975	iron-sulfur cluster assembly
C2L62_RS07020	COG2897	thiosulfate sulfurtransferase activity
C2L62_RS07025	COG2373	Large extracellular alpha-helical protein
C2L62_RS07030	COG4953	penicillin-binding protein 1C
C2L62_RS07065	COG2976	Protein conserved in bacteria
C2L62_RS07085	COG1645	bacterial-type flagellum-dependent swarming motility
C2L62_RS07095	COG0517	IMP dehydrogenase activity
C2L62_RS07095	COG0516	GMP reductase activity
C2L62_RS07145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2L62_RS07225	COG3344	reverse transcriptase
C2L62_RS07240	COG5484	DNA packaging
C2L62_RS07240	COG3728	DNA packaging
C2L62_RS07370	COG3039	Transposase
C2L62_RS07405	COG3179	chitinase
C2L62_RS07415	COG3119	arylsulfatase activity
C2L62_RS07420	COG0641	radical SAM
C2L62_RS07440	COG2200	EAL domain
C2L62_RS07455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C2L62_RS07470	COG2723	6-phospho-beta-galactosidase activity
C2L62_RS07480	COG2233	PERMEase
C2L62_RS07495	COG1393	Belongs to the ArsC family
C2L62_RS07500	COG4783	chaperone-mediated protein folding
C2L62_RS07505	COG0628	permease
C2L62_RS07510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2L62_RS07515	COG2716	regulation of RNA biosynthetic process
C2L62_RS07525	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C2L62_RS07535	COG2321	neutral zinc metallopeptidase
C2L62_RS07540	COG1444	tRNA N-acetyltransferase activity
C2L62_RS07545	COG0400	carboxylic ester hydrolase activity
C2L62_RS07560	COG1393	Belongs to the ArsC family
C2L62_RS07570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2L62_RS07580	COG0493	'glutamate synthase
C2L62_RS07580	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2L62_RS07590	COG5342	invasion associated locus B
C2L62_RS07595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C2L62_RS07600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C2L62_RS07610	COG4810	utilization protein
C2L62_RS07700	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2L62_RS07720	COG2837	iron assimilation
C2L62_RS07730	COG4150	thiosulfate binding
C2L62_RS07735	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C2L62_RS07740	COG4208	sulfate ABC transporter
C2L62_RS07745	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C2L62_RS07755	COG4319	ketosteroid isomerase
C2L62_RS07790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C2L62_RS07810	COG3530	Putative quorum-sensing-regulated virulence factor
C2L62_RS07815	COG0385	Bile acid
C2L62_RS07820	COG0583	DNA-binding transcription factor activity
C2L62_RS07855	COG3415	Transposase
C2L62_RS07860	COG3415	Transposase
C2L62_RS07875	COG2200	EAL domain
C2L62_RS07875	COG2199	diguanylate cyclase activity
C2L62_RS07880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2L62_RS07895	COG0667	Aldo Keto reductase
C2L62_RS07900	COG3961	Belongs to the TPP enzyme family
C2L62_RS07915	COG3279	Response regulator of the LytR AlgR family
C2L62_RS07920	COG3275	phosphorelay sensor kinase activity
C2L62_RS07930	COG0436	Aminotransferase
C2L62_RS07940	COG2807	transmembrane transport
C2L62_RS07945	COG0590	tRNA wobble adenosine to inosine editing
C2L62_RS07950	COG0583	DNA-binding transcription factor activity
C2L62_RS07970	COG2116	formate transmembrane transporter activity
C2L62_RS07975	COG2853	Lipoprotein
C2L62_RS07985	COG3691	Protein conserved in bacteria
C2L62_RS08000	COG2062	phosphohistidine phosphatase, SixA
C2L62_RS08025	COG0730	response to heat
C2L62_RS08030	COG3101	peptidyl-lysine hydroxylation
C2L62_RS08045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2L62_RS08065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C2L62_RS08075	COG0586	Pfam SNARE associated Golgi protein
C2L62_RS08085	COG0285	dihydrofolate synthase activity
C2L62_RS08090	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C2L62_RS08095	COG1286	toxin biosynthetic process
C2L62_RS08100	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C2L62_RS08105	COG0163	prenyltransferase activity
C2L62_RS08125	COG4160	amino acid transport
C2L62_RS08130	COG4598	ABC transporter
C2L62_RS08140	COG1090	epimerase
C2L62_RS08145	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C2L62_RS08150	COG0625	glutathione transferase activity
C2L62_RS08155	COG0625	glutathione transferase activity
C2L62_RS08160	COG0622	Phosphoesterase
C2L62_RS08165	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C2L62_RS08170	COG0280	phosphate acetyltransferase
C2L62_RS08170	COG0857	belongs to the CobB CobQ family
C2L62_RS08190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2L62_RS08195	COG0490	domain, Protein
C2L62_RS08195	COG0471	metal ion transport
C2L62_RS08205	COG0436	Aminotransferase
C2L62_RS08210	COG0583	DNA-binding transcription factor activity
C2L62_RS08260	COG0839	Belongs to the complex I subunit 6 family
C2L62_RS08270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C2L62_RS08275	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C2L62_RS08290	COG2153	protein acetylation
C2L62_RS08295	COG1169	isochorismate synthase
C2L62_RS08320	COG0318	PFAM AMP-dependent synthetase and ligase
C2L62_RS08330	COG5464	transposase or invertase
C2L62_RS08345	COG1414	Transcriptional regulator
C2L62_RS08355	COG2271	Major facilitator Superfamily
C2L62_RS08365	COG0247	lactate metabolic process
C2L62_RS08375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C2L62_RS08380	COG2271	Major facilitator Superfamily
C2L62_RS08385	COG0584	glycerophosphoryl diester phosphodiesterase
C2L62_RS08395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2L62_RS08425	COG2205	protein histidine kinase activity
C2L62_RS08425	COG0784	Response regulator, receiver
C2L62_RS08435	COG0642	Histidine kinase
C2L62_RS08435	COG2198	Histidine kinase
C2L62_RS08450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C2L62_RS08450	COG2169	Transcriptional regulator
C2L62_RS08455	COG3145	DNA-N1-methyladenine dioxygenase activity
C2L62_RS08460	COG4615	Cyclic peptide transporter
C2L62_RS08465	COG2239	Acts as a magnesium transporter
C2L62_RS08470	COG0659	secondary active sulfate transmembrane transporter activity
C2L62_RS08485	COG0628	permease
C2L62_RS08510	COG1349	DNA-binding transcription factor activity
C2L62_RS08515	COG0494	nUDIX hydrolase
C2L62_RS08535	COG1061	Type III restriction enzyme res subunit
C2L62_RS08540	COG1187	pseudouridine synthase activity
C2L62_RS08545	COG2814	Major facilitator Superfamily
C2L62_RS08555	COG4172	Belongs to the ABC transporter superfamily
C2L62_RS08560	COG4239	(ABC) transporter, permease
C2L62_RS08565	COG4174	ABC transporter (Permease)
C2L62_RS08570	COG4166	transmembrane transport
C2L62_RS08575	COG2200	EAL domain
C2L62_RS08580	COG0791	NLP P60 protein
C2L62_RS08585	COG0671	phosphoesterase, PA-phosphatase related
C2L62_RS08590	COG0523	cobalamin synthesis protein
C2L62_RS08595	COG0246	Mannitol dehydrogenase
C2L62_RS08600	COG1312	Catalyzes the dehydration of D-mannonate
C2L62_RS08630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS08630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS08635	COG1105	Belongs to the carbohydrate kinase PfkB family
C2L62_RS08640	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C2L62_RS08640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2L62_RS08640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2L62_RS08650	COG2855	membrane
C2L62_RS08660	COG0583	DNA-binding transcription factor activity
C2L62_RS08665	COG0833	amino acid
C2L62_RS08685	COG4771	TonB-dependent receptor
C2L62_RS08700	COG2311	Membrane
C2L62_RS08715	COG1129	ABC transporter
C2L62_RS08725	COG2949	membrane
C2L62_RS08735	COG1346	cytolysis
C2L62_RS08745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C2L62_RS08750	COG3659	wide pore channel activity
C2L62_RS08765	COG2723	6-phospho-beta-galactosidase activity
C2L62_RS08770	COG1538	Outer membrane efflux protein
C2L62_RS08775	COG0586	Pfam SNARE associated Golgi protein
C2L62_RS08785	COG1686	Belongs to the peptidase S11 family
C2L62_RS08795	COG0277	FAD linked oxidase domain protein
C2L62_RS08800	COG1472	Belongs to the glycosyl hydrolase 3 family
C2L62_RS08805	COG1732	Glycine betaine
C2L62_RS08810	COG1174	glycine betaine transport
C2L62_RS08815	COG1125	glycine betaine transport
C2L62_RS08820	COG1174	glycine betaine transport
C2L62_RS08830	COG3275	phosphorelay sensor kinase activity
C2L62_RS08840	COG4807	Protein conserved in bacteria
C2L62_RS08860	COG5455	response to cobalt ion
C2L62_RS08865	COG0583	DNA-binding transcription factor activity
C2L62_RS08870	COG2252	PERMEase
C2L62_RS08880	COG0583	DNA-binding transcription factor activity
C2L62_RS08900	COG0351	phosphomethylpyrimidine kinase
C2L62_RS08905	COG1830	Aldolase
C2L62_RS08940	COG1070	Carbohydrate kinase
C2L62_RS08950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2L62_RS08955	COG4948	Mandelate Racemase Muconate Lactonizing
C2L62_RS08960	COG0747	negative chemotaxis
C2L62_RS08965	COG0601	transmembrane transport
C2L62_RS08970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2L62_RS08975	COG0444	Belongs to the ABC transporter superfamily
C2L62_RS08980	COG4608	Belongs to the ABC transporter superfamily
C2L62_RS08990	COG0826	peptidase U32
C2L62_RS08995	COG0745	RESPONSE REGULATOR receiver
C2L62_RS09000	COG2205	protein histidine kinase activity
C2L62_RS09025	COG1301	dicarboxylic acid transport
C2L62_RS09040	COG5002	protein histidine kinase activity
C2L62_RS09045	COG0443	Heat shock 70 kDa protein
C2L62_RS09050	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C2L62_RS09065	COG2982	Protein involved in outer membrane biogenesis
C2L62_RS09070	COG1253	flavin adenine dinucleotide binding
C2L62_RS09115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C2L62_RS09130	COG0463	Glycosyl transferase, family 2
C2L62_RS09145	COG2244	polysaccharide biosynthetic process
C2L62_RS09155	COG1088	dTDP-glucose 4,6-dehydratase activity
C2L62_RS09190	COG1088	dTDP-glucose 4,6-dehydratase activity
C2L62_RS09255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C2L62_RS09285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2L62_RS09290	COG0583	DNA-binding transcription factor activity
C2L62_RS09300	COG0531	amino acid
C2L62_RS09305	COG0640	Transcriptional regulator
C2L62_RS09310	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C2L62_RS09315	COG2925	Exonuclease
C2L62_RS09330	COG3344	reverse transcriptase
C2L62_RS09340	COG1289	transmembrane transporter activity
C2L62_RS09360	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C2L62_RS09370	COG1942	4-Oxalocrotonate Tautomerase
C2L62_RS09375	COG0583	DNA-binding transcription factor activity
C2L62_RS09380	COG0095	Lipoate-protein ligase
C2L62_RS09385	COG0477	Major facilitator Superfamily
C2L62_RS09400	COG3300	MHYT domain
C2L62_RS09400	COG5001	Diguanylate cyclase
C2L62_RS09405	COG3615	Tellurite resistance protein tehB
C2L62_RS09430	COG3706	GGDEF domain
C2L62_RS09490	COG2003	Belongs to the UPF0758 family
C2L62_RS09545	COG3504	Conjugal transfer protein
C2L62_RS09620	COG4771	TonB-dependent receptor
C2L62_RS09625	COG1021	2,3-dihydroxybenzoate-AMP ligase
C2L62_RS09645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C2L62_RS09645	COG3433	isochorismatase activity
C2L62_RS09645	COG2226	methyltransferase
C2L62_RS09660	COG1132	(ABC) transporter
C2L62_RS09665	COG2814	Major facilitator Superfamily
C2L62_RS09670	COG1169	isochorismate synthase
C2L62_RS09675	COG0582	viral genome integration into host DNA
C2L62_RS09685	COG0534	Mate efflux family protein
C2L62_RS09695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C2L62_RS09715	COG0604	alcohol dehydrogenase
C2L62_RS09720	COG1309	transcriptional regulator
C2L62_RS09725	COG0025	NhaP-type Na H and K H
C2L62_RS09770	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C2L62_RS09785	COG1418	mRNA catabolic process
C2L62_RS09790	COG0270	DNA (cytosine-5-)-methyltransferase activity
C2L62_RS09795	COG3727	T/G mismatch-specific endonuclease activity
C2L62_RS09800	COG0697	spore germination
C2L62_RS09805	COG2354	Protein conserved in bacteria
C2L62_RS09835	COG0366	Alpha amylase catalytic
C2L62_RS09840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2L62_RS09850	COG0765	amino acid transport
C2L62_RS09855	COG1126	abc transporter atp-binding protein
C2L62_RS09860	COG2197	response regulator
C2L62_RS09870	COG2197	response regulator
C2L62_RS09910	COG3012	SEC-C Motif Domain Protein
C2L62_RS09910	COG3318	Belongs to the UPF0149 family
C2L62_RS09915	COG0814	amino acid
C2L62_RS09925	COG1528	Iron-storage protein
C2L62_RS09940	COG0477	Major facilitator Superfamily
C2L62_RS09950	COG2211	Major facilitator Superfamily
C2L62_RS09960	COG1528	Iron-storage protein
C2L62_RS09970	COG1879	ABC-type sugar transport system periplasmic component
C2L62_RS09980	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS10005	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C2L62_RS10015	COG3102	Protein conserved in bacteria
C2L62_RS10035	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C2L62_RS10040	COG1801	Protein of unknown function DUF72
C2L62_RS10045	COG1335	isochorismatase
C2L62_RS10055	COG0494	nUDIX hydrolase
C2L62_RS10080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2L62_RS10090	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C2L62_RS10095	COG0739	heme binding
C2L62_RS10100	COG1560	Kdo2-lipid A biosynthetic process
C2L62_RS10110	COG1737	Transcriptional regulator
C2L62_RS10125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C2L62_RS10130	COG0129	dihydroxy-acid dehydratase activity
C2L62_RS10135	COG0800	Aldolase
C2L62_RS10145	COG3141	response to X-ray
C2L62_RS10150	COG2979	Protein of unknown function (DUF533)
C2L62_RS10155	COG1770	oligopeptidase
C2L62_RS10160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2L62_RS10170	COG2372	response to copper ion
C2L62_RS10175	COG1276	copper resistance
C2L62_RS10190	COG2990	Protein conserved in bacteria
C2L62_RS10215	COG3008	intermembrane lipid transfer
C2L62_RS10220	COG2995	paraquat-inducible protein a
C2L62_RS10225	COG1956	GAF domain-containing protein
C2L62_RS10245	COG2814	Major facilitator Superfamily
C2L62_RS10255	COG1414	Transcriptional regulator
C2L62_RS10295	COG0768	penicillin binding
C2L62_RS10300	COG2226	methyltransferase
C2L62_RS10315	COG3716	PTS system mannose fructose sorbose family IID component
C2L62_RS10320	COG3715	PTS system
C2L62_RS10325	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS10325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2L62_RS10330	COG1253	flavin adenine dinucleotide binding
C2L62_RS10335	COG2200	EAL domain
C2L62_RS10340	COG1760	l-serine dehydratase
C2L62_RS10360	COG0251	oxidation-reduction process
C2L62_RS10365	COG1199	ATP-dependent helicase activity
C2L62_RS10375	COG3065	identical protein binding
C2L62_RS10385	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C2L62_RS10395	COG2894	cell division
C2L62_RS10410	COG0179	Fumarylacetoacetate (FAA) hydrolase
C2L62_RS10440	COG2719	SpoVR family
C2L62_RS10460	COG1619	proteins homologs of microcin C7 resistance protein MccF
C2L62_RS10470	COG4774	siderophore transport
C2L62_RS10485	COG2308	Evidence 4 Homologs of previously reported genes of
C2L62_RS10525	COG0583	DNA-binding transcription factor activity
C2L62_RS10530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C2L62_RS10545	COG1882	Formate acetyltransferase
C2L62_RS10575	COG0583	DNA-binding transcription factor activity
C2L62_RS10605	COG0583	DNA-binding transcription factor activity
C2L62_RS10620	COG3122	Protein conserved in bacteria
C2L62_RS10650	COG2885	chlorophyll binding
C2L62_RS10805	COG0012	GTP binding
C2L62_RS10825	COG0659	secondary active sulfate transmembrane transporter activity
C2L62_RS10855	COG2890	protein-(glutamine-N5) methyltransferase activity
C2L62_RS10875	COG0387	Pfam Sodium calcium exchanger
C2L62_RS10880	COG4572	Cation transport regulator
C2L62_RS10885	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C2L62_RS10895	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C2L62_RS10900	COG3707	response regulator
C2L62_RS10905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C2L62_RS10915	COG1116	anion transmembrane transporter activity
C2L62_RS10920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C2L62_RS10920	COG2146	nitrite reductase [NAD(P)H] activity
C2L62_RS10925	COG0243	molybdopterin cofactor binding
C2L62_RS10930	COG4932	domain protein
C2L62_RS10935	COG2197	response regulator
C2L62_RS10940	COG3850	Histidine kinase
C2L62_RS10945	COG2223	nitrite transmembrane transporter activity
C2L62_RS10950	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C2L62_RS10955	COG1140	nitrate reductase beta subunit
C2L62_RS10960	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C2L62_RS10965	COG2181	nitrate reductase activity
C2L62_RS10975	COG1522	sequence-specific DNA binding
C2L62_RS11010	COG0788	formyltetrahydrofolate deformylase activity
C2L62_RS11020	COG1752	Esterase of the alpha-beta hydrolase superfamily
C2L62_RS11025	COG0745	RESPONSE REGULATOR receiver
C2L62_RS11030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C2L62_RS11035	COG2916	Histone family protein nucleoid-structuring protein H-NS
C2L62_RS11040	COG1435	thymidine kinase activity
C2L62_RS11045	COG1454	alcohol dehydrogenase
C2L62_RS11045	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS11055	COG2095	MarC family integral membrane protein
C2L62_RS11060	COG4166	transmembrane transport
C2L62_RS11065	COG0601	transmembrane transport
C2L62_RS11070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2L62_RS11075	COG0444	Belongs to the ABC transporter superfamily
C2L62_RS11085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2L62_RS11105	COG2353	YceI-like domain
C2L62_RS11110	COG2350	Protein conserved in bacteria
C2L62_RS11120	COG3001	Fructosamine kinase
C2L62_RS11130	COG1105	Belongs to the carbohydrate kinase PfkB family
C2L62_RS11135	COG3137	Salt-induced outer membrane protein
C2L62_RS11180	COG0072	phenylalanine-tRNA ligase activity
C2L62_RS11180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C2L62_RS11200	COG0583	DNA-binding transcription factor activity
C2L62_RS11220	COG0386	Belongs to the glutathione peroxidase family
C2L62_RS11230	COG0791	NLP P60 protein
C2L62_RS11240	COG4256	Hemin uptake protein
C2L62_RS11245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C2L62_RS11255	COG0574	Belongs to the PEP-utilizing enzyme family
C2L62_RS11255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C2L62_RS11265	COG0628	permease
C2L62_RS11270	COG0277	FAD linked oxidase domain protein
C2L62_RS11270	COG0247	lactate metabolic process
C2L62_RS11275	COG2050	protein possibly involved in aromatic compounds catabolism
C2L62_RS11280	COG2261	transglycosylase associated protein
C2L62_RS11310	COG1120	ATPase activity
C2L62_RS11315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2L62_RS11325	COG0583	DNA-binding transcription factor activity
C2L62_RS11350	COG1304	FMN binding
C2L62_RS11355	COG1309	transcriptional regulator
C2L62_RS11370	COG0316	Belongs to the HesB IscA family
C2L62_RS11375	COG0719	Fe-S assembly protein
C2L62_RS11380	COG0396	ATPase activity
C2L62_RS11385	COG0719	Fe-S assembly protein
C2L62_RS11400	COG1376	ErfK ybiS ycfS ynhG family protein
C2L62_RS11425	COG1309	transcriptional regulator
C2L62_RS11430	COG3185	4-Hydroxyphenylpyruvate dioxygenase
C2L62_RS11430	COG1082	Xylose isomerase domain protein TIM barrel
C2L62_RS11435	COG2271	Major facilitator Superfamily
C2L62_RS11440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C2L62_RS11450	COG1120	ATPase activity
C2L62_RS11455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2L62_RS11460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2L62_RS11465	COG1414	Transcriptional regulator
C2L62_RS11500	COG2814	Major facilitator Superfamily
C2L62_RS11520	COG0583	DNA-binding transcription factor activity
C2L62_RS11525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2L62_RS11545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2L62_RS11550	COG1116	anion transmembrane transporter activity
C2L62_RS11555	COG4774	siderophore transport
C2L62_RS11560	COG1120	ATPase activity
C2L62_RS11565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2L62_RS11570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2L62_RS11590	COG0765	amino acid transport
C2L62_RS11595	COG1126	abc transporter atp-binding protein
C2L62_RS11625	COG1473	amidohydrolase
C2L62_RS11630	COG3383	formate dehydrogenase (NAD+) activity
C2L62_RS11635	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C2L62_RS11650	COG1175	transmembrane transport
C2L62_RS11680	COG4133	protoheme IX ABC transporter activity
C2L62_RS11685	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C2L62_RS11690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C2L62_RS11705	COG1138	Cytochrome C-type biogenesis protein
C2L62_RS11710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2L62_RS11715	COG4235	cytochrome complex assembly
C2L62_RS11715	COG3088	subunit of a heme lyase
C2L62_RS11755	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C2L62_RS11780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2L62_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS11820	COG2610	gluconate transmembrane transporter activity
C2L62_RS11825	COG1250	3-hydroxyacyl-CoA dehydrogenase
C2L62_RS11835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C2L62_RS11845	COG0583	DNA-binding transcription factor activity
C2L62_RS11870	COG0277	FAD linked oxidase domain protein
C2L62_RS11875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2L62_RS11900	COG0402	S-adenosylhomocysteine deaminase activity
C2L62_RS11950	COG0604	alcohol dehydrogenase
C2L62_RS11950	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS11950	COG3321	synthase
C2L62_RS11980	COG4608	Belongs to the ABC transporter superfamily
C2L62_RS11985	COG0444	Belongs to the ABC transporter superfamily
C2L62_RS12010	COG0346	lactoylglutathione lyase activity
C2L62_RS12015	COG1349	DNA-binding transcription factor activity
C2L62_RS12045	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C2L62_RS12100	COG0307	riboflavin synthase, alpha
C2L62_RS12105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C2L62_RS12110	COG2814	Major facilitator Superfamily
C2L62_RS12115	COG0583	DNA-binding transcription factor activity
C2L62_RS12130	COG2814	Major facilitator Superfamily
C2L62_RS12145	COG0791	NLP P60 protein
C2L62_RS12150	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C2L62_RS12160	COG0346	lactoylglutathione lyase activity
C2L62_RS12165	COG1902	pentaerythritol trinitrate reductase activity
C2L62_RS12170	COG1309	transcriptional regulator
C2L62_RS12175	COG3313	Fe-S protein
C2L62_RS12180	COG4989	oxidoreductase activity
C2L62_RS12185	COG2032	superoxide dismutase activity
C2L62_RS12190	COG1289	transmembrane transporter activity
C2L62_RS12195	COG1566	PFAM secretion protein HlyD family protein
C2L62_RS12210	COG3706	GGDEF domain
C2L62_RS12225	COG3895	Periplasmic Protein
C2L62_RS12240	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C2L62_RS12245	COG0625	glutathione transferase activity
C2L62_RS12260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C2L62_RS12270	COG4659	FMN binding
C2L62_RS12305	COG2723	6-phospho-beta-galactosidase activity
C2L62_RS12315	COG0673	inositol 2-dehydrogenase activity
C2L62_RS12325	COG2814	Major facilitator Superfamily
C2L62_RS12345	COG3038	cytochrome b561
C2L62_RS12365	COG0583	DNA-binding transcription factor activity
C2L62_RS12370	COG3485	protocatechuate 3,4-dioxygenase
C2L62_RS12375	COG3485	protocatechuate 3,4-dioxygenase
C2L62_RS12380	COG5383	Protein conserved in bacteria
C2L62_RS12385	COG2272	Belongs to the type-B carboxylesterase lipase family
C2L62_RS12400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2L62_RS12405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C2L62_RS12410	COG1275	C4-dicarboxylate transporter malic acid transport protein
C2L62_RS12415	COG0500	methyltransferase
C2L62_RS12430	COG2207	Transcriptional regulator
C2L62_RS12430	COG3708	Transcriptional regulator
C2L62_RS12435	COG3135	benzoate transporter
C2L62_RS12440	COG1396	sequence-specific DNA binding
C2L62_RS12450	COG0826	peptidase U32
C2L62_RS12470	COG1294	oxidase, subunit
C2L62_RS12475	COG1271	oxidase subunit
C2L62_RS12480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2L62_RS12485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C2L62_RS12490	COG3842	ATPase activity
C2L62_RS12495	COG1176	ABC-type spermidine putrescine transport system, permease component I
C2L62_RS12500	COG1177	transmembrane transport
C2L62_RS12505	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS12535	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS12540	COG0747	negative chemotaxis
C2L62_RS12550	COG3238	Protein conserved in bacteria
C2L62_RS12555	COG1247	-acetyltransferase
C2L62_RS12565	COG2130	NADP-dependent
C2L62_RS12580	COG3691	Protein conserved in bacteria
C2L62_RS12585	COG1228	amidohydrolase
C2L62_RS12590	COG4772	TonB-dependent receptor
C2L62_RS12615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C2L62_RS12620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2L62_RS12625	COG1473	amidohydrolase
C2L62_RS12630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2L62_RS12635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2L62_RS12645	COG0765	amino acid transport
C2L62_RS12650	COG1126	abc transporter atp-binding protein
C2L62_RS12660	COG0625	glutathione transferase activity
C2L62_RS12690	COG2211	Major facilitator Superfamily
C2L62_RS12705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C2L62_RS12710	COG3842	ATPase activity
C2L62_RS12715	COG1840	ABC-type Fe3 transport system, periplasmic component
C2L62_RS12720	COG1178	ABC-type Fe3 transport system permease component
C2L62_RS12725	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C2L62_RS12730	COG2181	nitrate reductase activity
C2L62_RS12735	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C2L62_RS12740	COG1140	nitrate reductase beta subunit
C2L62_RS12745	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C2L62_RS12765	COG1414	Transcriptional regulator
C2L62_RS12770	COG4948	Mandelate Racemase Muconate Lactonizing
C2L62_RS12775	COG4829	muconolactone delta-isomerase
C2L62_RS12780	COG3485	protocatechuate 3,4-dioxygenase
C2L62_RS12790	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C2L62_RS12810	COG3383	formate dehydrogenase (NAD+) activity
C2L62_RS12810	COG0243	molybdopterin cofactor binding
C2L62_RS12815	COG0243	molybdopterin cofactor binding
C2L62_RS12815	COG3383	formate dehydrogenase (NAD+) activity
C2L62_RS12820	COG0437	4 iron, 4 sulfur cluster binding
C2L62_RS12825	COG2864	formate dehydrogenase
C2L62_RS12840	COG2326	polyphosphate kinase activity
C2L62_RS12850	COG2814	Major facilitator Superfamily
C2L62_RS12860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2L62_RS12870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2L62_RS12880	COG0747	negative chemotaxis
C2L62_RS12885	COG1064	alcohol dehydrogenase
C2L62_RS12900	COG0488	(ABC) transporter
C2L62_RS12940	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS12945	COG3729	General stress protein
C2L62_RS12960	COG3685	Protein conserved in bacteria
C2L62_RS12970	COG0366	Alpha amylase catalytic
C2L62_RS12980	COG2323	membrane
C2L62_RS12990	COG3111	PFAM Bacterial OB fold (BOF) protein
C2L62_RS12995	COG1764	response to oxidative stress
C2L62_RS13020	COG3781	membrane
C2L62_RS13025	COG0243	molybdopterin cofactor binding
C2L62_RS13030	COG0583	DNA-binding transcription factor activity
C2L62_RS13035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS13060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS13065	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2L62_RS13070	COG2814	Major facilitator Superfamily
C2L62_RS13080	COG1285	pathogenesis
C2L62_RS13085	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C2L62_RS13095	COG0583	DNA-binding transcription factor activity
C2L62_RS13115	COG0519	Catalyzes the synthesis of GMP from XMP
C2L62_RS13115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C2L62_RS13155	COG0596	Alpha beta hydrolase
C2L62_RS13165	COG2205	protein histidine kinase activity
C2L62_RS13180	COG0076	glutamate decarboxylase activity
C2L62_RS13185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C2L62_RS13190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C2L62_RS13195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2L62_RS13200	COG1116	anion transmembrane transporter activity
C2L62_RS13205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C2L62_RS13215	COG0673	inositol 2-dehydrogenase activity
C2L62_RS13225	COG1609	Transcriptional regulator
C2L62_RS13230	COG3706	GGDEF domain
C2L62_RS13235	COG0402	S-adenosylhomocysteine deaminase activity
C2L62_RS13240	COG1953	Uracil, thiamine, allantoin
C2L62_RS13275	COG0406	alpha-ribazole phosphatase activity
C2L62_RS13285	COG1335	isochorismatase
C2L62_RS13325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2L62_RS13395	COG0765	amino acid transport
C2L62_RS13405	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C2L62_RS13415	COG2070	2-Nitropropane dioxygenase
C2L62_RS13420	COG0583	DNA-binding transcription factor activity
C2L62_RS13430	COG1902	pentaerythritol trinitrate reductase activity
C2L62_RS13435	COG4529	Protein conserved in bacteria
C2L62_RS13440	COG0477	Major facilitator Superfamily
C2L62_RS13470	COG2223	nitrite transmembrane transporter activity
C2L62_RS13480	COG1609	Transcriptional regulator
C2L62_RS13485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS13495	COG3037	sugar-specific permease SgaT UlaA
C2L62_RS13500	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C2L62_RS13510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2L62_RS13515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2L62_RS13515	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C2L62_RS13515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2L62_RS13530	COG0583	DNA-binding transcription factor activity
C2L62_RS13535	COG0583	DNA-binding transcription factor activity
C2L62_RS13540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2L62_RS13550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C2L62_RS13565	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS13575	COG1609	Transcriptional regulator
C2L62_RS13605	COG1652	LysM domain
C2L62_RS13620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C2L62_RS13620	COG0426	domain, Protein
C2L62_RS13645	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C2L62_RS13645	COG0456	acetyltransferase
C2L62_RS13655	COG0667	Aldo Keto reductase
C2L62_RS13660	COG0667	Aldo Keto reductase
C2L62_RS13670	COG0667	Aldo Keto reductase
C2L62_RS13685	COG4977	sequence-specific DNA binding
C2L62_RS13705	COG4977	sequence-specific DNA binding
C2L62_RS13710	COG1349	DNA-binding transcription factor activity
C2L62_RS13725	COG1349	DNA-binding transcription factor activity
C2L62_RS13730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C2L62_RS13735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2L62_RS13740	COG0738	Major facilitator superfamily
C2L62_RS13785	COG1929	Belongs to the glycerate kinase type-1 family
C2L62_RS13790	COG3835	regulator
C2L62_RS13810	COG2186	Transcriptional regulator
C2L62_RS13815	COG1263	PTS System
C2L62_RS13815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2L62_RS13825	COG2814	Major facilitator Superfamily
C2L62_RS13830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS13830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS13840	COG2819	hydrolase of the alpha beta superfamily
C2L62_RS13845	COG5001	Diguanylate cyclase
C2L62_RS13845	COG3300	MHYT domain
C2L62_RS13880	COG3188	usher protein
C2L62_RS13890	COG1649	PFAM Uncharacterised BCR, COG1649
C2L62_RS13895	COG3550	peptidyl-serine autophosphorylation
C2L62_RS13900	COG1396	sequence-specific DNA binding
C2L62_RS13905	COG2351	hydroxyisourate hydrolase activity
C2L62_RS13910	COG3648	Uricase
C2L62_RS13910	COG3195	allantoin biosynthetic process
C2L62_RS13915	COG2233	PERMEase
C2L62_RS13945	COG2207	Transcriptional regulator
C2L62_RS13960	COG4628	conserved protein (DUF2132)
C2L62_RS13980	COG2011	ABC-type metal ion transport system permease component
C2L62_RS13985	COG2070	2-Nitropropane dioxygenase
C2L62_RS13995	COG0477	Major facilitator Superfamily
C2L62_RS14075	COG2199	diguanylate cyclase activity
C2L62_RS14090	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS14095	COG0583	DNA-binding transcription factor activity
C2L62_RS14105	COG0039	L-malate dehydrogenase activity
C2L62_RS14110	COG1349	DNA-binding transcription factor activity
C2L62_RS14115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C2L62_RS14120	COG3395	kinase activity
C2L62_RS14130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C2L62_RS14145	COG2731	YhcH YjgK YiaL family protein
C2L62_RS14150	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS14175	COG4977	sequence-specific DNA binding
C2L62_RS14185	COG0697	spore germination
C2L62_RS14190	COG2814	Major facilitator Superfamily
C2L62_RS14200	COG0410	ABC transporter
C2L62_RS14205	COG1129	ABC transporter
C2L62_RS14220	COG0683	leucine binding
C2L62_RS14225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C2L62_RS14260	COG2223	nitrite transmembrane transporter activity
C2L62_RS14265	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C2L62_RS14280	COG1349	DNA-binding transcription factor activity
C2L62_RS14285	COG2084	Dehydrogenase
C2L62_RS14290	COG3395	kinase activity
C2L62_RS14295	COG0235	Class ii aldolase
C2L62_RS14300	COG3622	Belongs to the hyi family
C2L62_RS14305	COG2610	gluconate transmembrane transporter activity
C2L62_RS14310	COG2207	Transcriptional regulator
C2L62_RS14310	COG3708	Transcriptional regulator
C2L62_RS14325	COG2200	EAL domain
C2L62_RS14330	COG1546	Belongs to the CinA family
C2L62_RS14335	COG0071	Belongs to the small heat shock protein (HSP20) family
C2L62_RS14345	COG2197	response regulator
C2L62_RS14350	COG2135	peptidase activity
C2L62_RS14355	COG2207	Transcriptional regulator
C2L62_RS14370	COG4221	oxidoreductase activity
C2L62_RS14375	COG1802	Transcriptional regulator
C2L62_RS14380	COG0589	response to stress
C2L62_RS14385	COG0246	Mannitol dehydrogenase
C2L62_RS14390	COG2271	Major facilitator Superfamily
C2L62_RS14405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2L62_RS14420	COG0243	molybdopterin cofactor binding
C2L62_RS14425	COG0437	4 iron, 4 sulfur cluster binding
C2L62_RS14430	COG3302	dmso reductase anchor subunit
C2L62_RS14445	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C2L62_RS14450	COG1940	carbohydrate kinase activity
C2L62_RS14455	COG0583	DNA-binding transcription factor activity
C2L62_RS14460	COG2814	Major facilitator Superfamily
C2L62_RS14465	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C2L62_RS14475	COG3591	Belongs to the peptidase S1B family
C2L62_RS14495	COG0628	permease
C2L62_RS14525	COG0679	Auxin Efflux Carrier
C2L62_RS14535	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C2L62_RS14560	COG3290	protein histidine kinase activity
C2L62_RS14565	COG4565	transcriptional regulatory protein
C2L62_RS14590	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C2L62_RS14590	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C2L62_RS14610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2L62_RS14615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C2L62_RS14625	COG0183	Belongs to the thiolase family
C2L62_RS14630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C2L62_RS14640	COG1414	Transcriptional regulator
C2L62_RS14645	COG2840	Smr protein MutS2
C2L62_RS14650	COG0583	DNA-binding transcription factor activity
C2L62_RS14660	COG1473	amidohydrolase
C2L62_RS14665	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C2L62_RS14680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2L62_RS14695	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C2L62_RS14700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C2L62_RS14720	COG0531	amino acid
C2L62_RS14730	COG3136	membrane protein required for alginate biosynthesis
C2L62_RS14735	COG0745	RESPONSE REGULATOR receiver
C2L62_RS14745	COG2205	protein histidine kinase activity
C2L62_RS14755	COG0114	fumarate hydratase activity
C2L62_RS14760	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C2L62_RS14760	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C2L62_RS14765	COG1482	cell wall glycoprotein biosynthetic process
C2L62_RS14770	COG5339	Protein conserved in bacteria
C2L62_RS14775	COG1609	Transcriptional regulator
C2L62_RS14780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2L62_RS14780	COG1263	PTS System
C2L62_RS14785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C2L62_RS14810	COG2391	methyltransferase activity
C2L62_RS14815	COG0425	Belongs to the sulfur carrier protein TusA family
C2L62_RS14820	COG5562	phage envelope protein
C2L62_RS14825	COG0401	homolog of Blt101
C2L62_RS14830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C2L62_RS14835	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS14840	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C2L62_RS14845	COG0477	Major facilitator Superfamily
C2L62_RS14850	COG1113	amino acid transport
C2L62_RS14855	COG2988	succinylglutamate desuccinylase activity
C2L62_RS14860	COG3724	N-succinylarginine dihydrolase activity
C2L62_RS14865	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS14870	COG3138	arginine N-succinyltransferase
C2L62_RS14875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C2L62_RS14880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C2L62_RS14885	COG0667	Aldo Keto reductase
C2L62_RS14890	COG0583	DNA-binding transcription factor activity
C2L62_RS14915	COG4122	O-methyltransferase activity
C2L62_RS14920	COG1643	Atp-dependent helicase
C2L62_RS14935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C2L62_RS14940	COG3327	negative regulation of DNA-templated transcription, initiation
C2L62_RS14945	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C2L62_RS14950	COG0183	Belongs to the thiolase family
C2L62_RS14955	COG2050	protein possibly involved in aromatic compounds catabolism
C2L62_RS14960	COG1250	3-hydroxyacyl-CoA dehydrogenase
C2L62_RS14965	COG1024	Enoyl-CoA hydratase
C2L62_RS14970	COG1024	Enoyl-CoA hydratase
C2L62_RS14975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2L62_RS14980	COG2151	metal-sulfur cluster biosynthetic enzyme
C2L62_RS14985	COG3396	Phenylacetate-CoA oxygenase
C2L62_RS14990	COG3460	Phenylacetate-CoA oxygenase
C2L62_RS14995	COG3396	Phenylacetate-CoA oxygenase
C2L62_RS15000	COG2030	dehydratase
C2L62_RS15000	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS15030	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS15035	COG2207	Transcriptional regulator
C2L62_RS15040	COG3784	Protein of unknown function (DUF1318)
C2L62_RS15050	COG2911	Protein conserved in bacteria
C2L62_RS15055	COG0586	Pfam SNARE associated Golgi protein
C2L62_RS15060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C2L62_RS15065	COG3187	Heat shock protein
C2L62_RS15070	COG3042	response to heat
C2L62_RS15080	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C2L62_RS15080	COG1013	pyruvate-flavodoxin oxidoreductase activity
C2L62_RS15080	COG0674	pyruvate-flavodoxin oxidoreductase activity
C2L62_RS15080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C2L62_RS15085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C2L62_RS15095	COG0589	response to stress
C2L62_RS15105	COG0513	Belongs to the DEAD box helicase family
C2L62_RS15120	COG1349	DNA-binding transcription factor activity
C2L62_RS15125	COG0673	inositol 2-dehydrogenase activity
C2L62_RS15140	COG1113	amino acid transport
C2L62_RS15145	COG1522	sequence-specific DNA binding
C2L62_RS15155	COG1448	Aminotransferase
C2L62_RS15160	COG2011	ABC-type metal ion transport system permease component
C2L62_RS15175	COG0436	Aminotransferase
C2L62_RS15180	COG0604	alcohol dehydrogenase
C2L62_RS15205	COG0583	DNA-binding transcription factor activity
C2L62_RS15225	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS15230	COG1309	transcriptional regulator
C2L62_RS15235	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS15330	COG2885	chlorophyll binding
C2L62_RS15455	COG0741	lytic transglycosylase activity
C2L62_RS15455	COG0739	heme binding
C2L62_RS15455	COG1196	nuclear chromosome segregation
C2L62_RS15525	COG3567	Phage-associated protein, HI1409 family
C2L62_RS15530	COG1783	phage Terminase large subunit
C2L62_RS15555	COG3772	lysozyme
C2L62_RS15565	COG0484	heat shock protein binding
C2L62_RS15670	COG0582	viral genome integration into host DNA
C2L62_RS15675	COG0693	protein deglycase activity
C2L62_RS15680	COG1078	dGTPase activity
C2L62_RS15685	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS15690	COG0583	DNA-binding transcription factor activity
C2L62_RS15710	COG0656	L-ascorbic acid biosynthetic process
C2L62_RS15740	COG4166	transmembrane transport
C2L62_RS15745	COG2866	Carboxypeptidase
C2L62_RS15750	COG4948	Mandelate Racemase Muconate Lactonizing
C2L62_RS15755	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C2L62_RS15760	COG3180	Ammonia monooxygenase
C2L62_RS15770	COG1486	melibiose metabolic process
C2L62_RS15775	COG0583	DNA-binding transcription factor activity
C2L62_RS15785	COG3106	COG3106 Predicted ATPase
C2L62_RS15795	COG1983	PspC domain protein
C2L62_RS15805	COG1842	Phage shock protein A
C2L62_RS15810	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C2L62_RS15820	COG1473	amidohydrolase
C2L62_RS15835	COG0702	epimerase
C2L62_RS15850	COG2135	peptidase activity
C2L62_RS15860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C2L62_RS15865	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C2L62_RS15870	COG3344	reverse transcriptase
C2L62_RS15955	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C2L62_RS16075	COG4171	peptide transport system, permease
C2L62_RS16090	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C2L62_RS16100	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C2L62_RS16105	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2L62_RS16105	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2L62_RS16120	COG1349	DNA-binding transcription factor activity
C2L62_RS16130	COG0023	Translation Initiation Factor
C2L62_RS16140	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C2L62_RS16145	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C2L62_RS16150	COG0671	phosphoesterase, PA-phosphatase related
C2L62_RS16160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C2L62_RS16190	COG0616	signal peptide processing
C2L62_RS16200	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS16205	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C2L62_RS16215	COG0583	DNA-binding transcription factor activity
C2L62_RS16225	COG0009	L-threonylcarbamoyladenylate synthase
C2L62_RS16235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C2L62_RS16240	COG0512	Glutamine amidotransferase of anthranilate synthase
C2L62_RS16240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C2L62_RS16245	COG0135	phosphoribosylanthranilate isomerase activity
C2L62_RS16245	COG0134	indole-3-glycerol-phosphate synthase activity
C2L62_RS16300	COG4774	siderophore transport
C2L62_RS16310	COG3047	cAMP biosynthetic process
C2L62_RS16315	COG0727	PFAM Uncharacterised protein family (UPF0153)
C2L62_RS16345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2L62_RS16350	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS16355	COG1988	membrane-bound metal-dependent
C2L62_RS16360	COG1823	symporter activity
C2L62_RS16370	COG0753	catalase activity
C2L62_RS16380	COG1486	melibiose metabolic process
C2L62_RS16385	COG1917	Cupin 2, conserved barrel domain protein
C2L62_RS16385	COG2169	Transcriptional regulator
C2L62_RS16390	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2L62_RS16395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS16400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS16405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2L62_RS16415	COG0322	excinuclease ABC activity
C2L62_RS16420	COG3678	ATP-independent chaperone mediated protein folding
C2L62_RS16430	COG3724	N-succinylarginine dihydrolase activity
C2L62_RS16440	COG3138	arginine N-succinyltransferase
C2L62_RS16450	COG0708	Exodeoxyribonuclease III
C2L62_RS16455	COG0398	Pfam SNARE associated Golgi protein
C2L62_RS16460	COG0398	Pfam SNARE associated Golgi protein
C2L62_RS16465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2L62_RS16470	COG4134	Bacterial extracellular solute-binding protein
C2L62_RS16475	COG4135	transport system, permease component
C2L62_RS16480	COG4136	ATPase activity
C2L62_RS16485	COG2897	thiosulfate sulfurtransferase activity
C2L62_RS16490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C2L62_RS16495	COG0494	nUDIX hydrolase
C2L62_RS16500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C2L62_RS16505	COG0604	alcohol dehydrogenase
C2L62_RS16505	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS16505	COG3321	synthase
C2L62_RS16510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C2L62_RS16515	COG0709	Synthesizes selenophosphate from selenide and ATP
C2L62_RS16535	COG0778	Nitroreductase
C2L62_RS16540	COG0616	signal peptide processing
C2L62_RS16545	COG0252	asparaginase activity
C2L62_RS16550	COG1335	isochorismatase
C2L62_RS16555	COG2814	Major facilitator Superfamily
C2L62_RS16560	COG1349	DNA-binding transcription factor activity
C2L62_RS16565	COG0667	Aldo Keto reductase
C2L62_RS16570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2L62_RS16575	COG0191	fructose-bisphosphate aldolase activity
C2L62_RS16580	COG1063	alcohol dehydrogenase
C2L62_RS16585	COG2271	Major facilitator Superfamily
C2L62_RS16590	COG1063	alcohol dehydrogenase
C2L62_RS16605	COG3139	Protein of unknown function (DUF1315)
C2L62_RS16630	COG3713	MltA-interacting MipA family protein
C2L62_RS16635	COG2766	serine protein kinase
C2L62_RS16650	COG0386	Belongs to the glutathione peroxidase family
C2L62_RS16670	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS16675	COG0583	DNA-binding transcription factor activity
C2L62_RS16680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C2L62_RS16685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C2L62_RS16690	COG3344	reverse transcriptase
C2L62_RS16705	COG0859	PFAM glycosyl transferase family 9
C2L62_RS16710	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C2L62_RS16720	COG2207	Transcriptional regulator
C2L62_RS16725	COG2807	transmembrane transport
C2L62_RS16730	COG0504	CTP synthase activity
C2L62_RS16735	COG1683	Conserved Protein
C2L62_RS16740	COG3189	MarR family transcriptional regulator
C2L62_RS16745	COG3042	response to heat
C2L62_RS16750	COG2199	diguanylate cyclase activity
C2L62_RS16750	COG2203	Gaf domain
C2L62_RS16770	COG3182	Iron-regulated membrane protein
C2L62_RS16780	COG1560	Kdo2-lipid A biosynthetic process
C2L62_RS16795	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C2L62_RS16800	COG3706	GGDEF domain
C2L62_RS16805	COG0583	DNA-binding transcription factor activity
C2L62_RS16810	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C2L62_RS16835	COG1294	oxidase, subunit
C2L62_RS16840	COG1271	oxidase subunit
C2L62_RS16845	COG3546	catalase activity
C2L62_RS16850	COG3685	Protein conserved in bacteria
C2L62_RS16855	COG3685	Protein conserved in bacteria
C2L62_RS16860	COG3729	General stress protein
C2L62_RS16865	COG1063	alcohol dehydrogenase
C2L62_RS16870	COG3813	Protein conserved in bacteria
C2L62_RS16885	COG0640	Transcriptional regulator
C2L62_RS16890	COG0538	isocitrate dehydrogenase activity
C2L62_RS16980	COG0616	signal peptide processing
C2L62_RS16995	COG4626	Terminase
C2L62_RS16995	COG1802	Transcriptional regulator
C2L62_RS17035	COG3772	lysozyme
C2L62_RS17055	COG1403	HNH endonuclease
C2L62_RS17080	COG3344	reverse transcriptase
C2L62_RS17090	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C2L62_RS17135	COG1396	sequence-specific DNA binding
C2L62_RS17160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2L62_RS17170	COG0582	viral genome integration into host DNA
C2L62_RS17175	COG0538	isocitrate dehydrogenase activity
C2L62_RS17180	COG1187	pseudouridine synthase activity
C2L62_RS17200	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C2L62_RS17220	COG2205	protein histidine kinase activity
C2L62_RS17225	COG2850	peptidyl-arginine hydroxylation
C2L62_RS17245	COG1177	transmembrane transport
C2L62_RS17260	COG0318	PFAM AMP-dependent synthetase and ligase
C2L62_RS17270	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C2L62_RS17280	COG4591	ABC-type transport system involved in lipoprotein release permease component
C2L62_RS17290	COG4591	ABC-type transport system involved in lipoprotein release permease component
C2L62_RS17295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C2L62_RS17300	COG1388	LysM domain
C2L62_RS17300	COG1376	ErfK ybiS ycfS ynhG family protein
C2L62_RS17310	COG1309	transcriptional regulator
C2L62_RS17320	COG3134	Outer membrane lipoprotein
C2L62_RS17325	COG1252	NADH dehydrogenase
C2L62_RS17350	COG5633	Lipoprotein
C2L62_RS17355	COG0537	adenosine 5'-monophosphoramidase activity
C2L62_RS17365	COG0084	hydrolase, TatD family'
C2L62_RS17370	COG0470	DNA polymerase III
C2L62_RS17380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C2L62_RS17385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C2L62_RS17390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2L62_RS17405	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C2L62_RS17425	COG1399	metal-binding, possibly nucleic acid-binding protein
C2L62_RS17445	COG1530	ribonuclease E activity
C2L62_RS17450	COG0583	DNA-binding transcription factor activity
C2L62_RS17455	COG2814	Major facilitator Superfamily
C2L62_RS17475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2L62_RS17525	COG1560	Kdo2-lipid A biosynthetic process
C2L62_RS17545	COG5645	(Lipo)protein
C2L62_RS17585	COG3381	protein complex oligomerization
C2L62_RS17615	COG0583	DNA-binding transcription factor activity
C2L62_RS17625	COG1335	isochorismatase
C2L62_RS17635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C2L62_RS17640	COG1702	phosphate starvation-inducible protein PhoH
C2L62_RS17660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2L62_RS17670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C2L62_RS17685	COG1309	transcriptional regulator
C2L62_RS17720	COG2233	PERMEase
C2L62_RS17735	COG3729	General stress protein
C2L62_RS17760	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS17775	COG0531	amino acid
C2L62_RS17785	COG0174	glutamine synthetase
C2L62_RS17790	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C2L62_RS17795	COG1917	Cupin 2, conserved barrel domain protein
C2L62_RS17795	COG1396	sequence-specific DNA binding
C2L62_RS17800	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS17805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C2L62_RS17810	COG0583	DNA-binding transcription factor activity
C2L62_RS17815	COG0473	3-isopropylmalate dehydrogenase activity
C2L62_RS17825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C2L62_RS17830	COG4638	Rieske (2fe-2S)
C2L62_RS17835	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS17840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2L62_RS17850	COG2200	EAL domain
C2L62_RS17855	COG2200	EAL domain
C2L62_RS17870	COG0670	Belongs to the BI1 family
C2L62_RS17885	COG2207	Transcriptional regulator
C2L62_RS17890	COG1881	PFAM PEBP family protein
C2L62_RS17905	COG1832	CoA-binding protein
C2L62_RS17915	COG0210	DNA helicase
C2L62_RS17920	COG3304	Inner membrane component domain
C2L62_RS17925	COG1289	transmembrane transporter activity
C2L62_RS17930	COG3070	regulator of competence-specific genes
C2L62_RS17955	COG1067	ATP-dependent peptidase activity
C2L62_RS17965	COG3130	regulation of translation
C2L62_RS17970	COG3009	Protein conserved in bacteria
C2L62_RS17975	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C2L62_RS17975	COG3008	intermembrane lipid transfer
C2L62_RS17980	COG2995	paraquat-inducible protein a
C2L62_RS17985	COG0488	(ABC) transporter
C2L62_RS17995	COG3217	Mosc domain protein beta barrel domain protein
C2L62_RS17995	COG0633	Ferredoxin
C2L62_RS18010	COG0431	NADPH-dependent FMN reductase
C2L62_RS18015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C2L62_RS18020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2L62_RS18025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2L62_RS18035	COG0308	aminopeptidase N
C2L62_RS18045	COG1473	amidohydrolase
C2L62_RS18055	COG0814	amino acid
C2L62_RS18065	COG1522	sequence-specific DNA binding
C2L62_RS18080	COG1448	Aminotransferase
C2L62_RS18085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2L62_RS18090	COG3108	Peptidase M15
C2L62_RS18095	COG2989	Protein conserved in bacteria
C2L62_RS18105	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C2L62_RS18115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C2L62_RS18120	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C2L62_RS18125	COG3173	Aminoglycoside phosphotransferase
C2L62_RS18140	COG3214	Protein conserved in bacteria
C2L62_RS18155	COG0658	competence protein
C2L62_RS18155	COG2333	competence protein COMEC
C2L62_RS18165	COG0539	negative regulation of cytoplasmic translation
C2L62_RS18185	COG2323	membrane
C2L62_RS18190	COG1944	ATP diphosphatase activity
C2L62_RS18195	COG2116	formate transmembrane transporter activity
C2L62_RS18200	COG1882	Formate acetyltransferase
C2L62_RS18205	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C2L62_RS18210	COG0477	Major facilitator Superfamily
C2L62_RS18220	COG3302	dmso reductase anchor subunit
C2L62_RS18225	COG0437	4 iron, 4 sulfur cluster binding
C2L62_RS18230	COG0243	molybdopterin cofactor binding
C2L62_RS18240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C2L62_RS18250	COG1674	ftsk spoiiie
C2L62_RS18250	COG1178	ABC-type Fe3 transport system permease component
C2L62_RS18260	COG0492	ferredoxin-NADP+ reductase activity
C2L62_RS18265	COG4988	ABC transporter
C2L62_RS18270	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C2L62_RS18285	COG0542	response to heat
C2L62_RS18295	COG1278	Cold shock
C2L62_RS18305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2L62_RS18310	COG3593	DNA synthesis involved in DNA repair
C2L62_RS18320	COG2431	L-lysine efflux transmembrane transporter activity
C2L62_RS18330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2L62_RS18345	COG0028	Belongs to the TPP enzyme family
C2L62_RS18350	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C2L62_RS18355	COG0702	epimerase
C2L62_RS18360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2L62_RS18365	COG3023	N-Acetylmuramoyl-L-alanine amidase
C2L62_RS18370	COG4251	negative regulation of phosphorylation
C2L62_RS18370	COG3706	GGDEF domain
C2L62_RS18370	COG2203	Gaf domain
C2L62_RS18370	COG5001	Diguanylate cyclase
C2L62_RS18385	COG1126	abc transporter atp-binding protein
C2L62_RS18390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2L62_RS18395	COG4215	(ABC) transporter
C2L62_RS18400	COG4160	amino acid transport
C2L62_RS18405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2L62_RS18410	COG5002	protein histidine kinase activity
C2L62_RS18415	COG0745	RESPONSE REGULATOR receiver
C2L62_RS18430	COG1177	transmembrane transport
C2L62_RS18435	COG1176	ABC-type spermidine putrescine transport system, permease component I
C2L62_RS18440	COG3842	ATPase activity
C2L62_RS18445	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C2L62_RS18630	COG4695	Portal protein
C2L62_RS18655	COG3344	reverse transcriptase
C2L62_RS18675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2L62_RS18715	COG3344	reverse transcriptase
C2L62_RS18725	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C2L62_RS18730	COG3226	Transcriptional regulator
C2L62_RS18735	COG0738	Major facilitator superfamily
C2L62_RS18740	COG0561	phosphatase activity
C2L62_RS18745	COG2814	Major facilitator Superfamily
C2L62_RS18755	COG0671	phosphoesterase, PA-phosphatase related
C2L62_RS18760	COG1349	DNA-binding transcription factor activity
C2L62_RS18765	COG1686	Belongs to the peptidase S11 family
C2L62_RS18770	COG0625	glutathione transferase activity
C2L62_RS18775	COG2133	pyrroloquinoline quinone binding
C2L62_RS18785	COG2223	nitrite transmembrane transporter activity
C2L62_RS18810	COG0747	negative chemotaxis
C2L62_RS18825	COG0303	'Molybdopterin
C2L62_RS18830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C2L62_RS18835	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C2L62_RS18840	COG1882	Formate acetyltransferase
C2L62_RS18845	COG0561	phosphatase activity
C2L62_RS18855	COG1609	Transcriptional regulator
C2L62_RS18860	COG2271	Major facilitator Superfamily
C2L62_RS18875	COG0488	(ABC) transporter
C2L62_RS18880	COG2365	Tyrosine phosphatase family
C2L62_RS18885	COG1376	ErfK ybiS ycfS ynhG family protein
C2L62_RS18890	COG2188	Transcriptional regulator
C2L62_RS18895	COG2723	6-phospho-beta-galactosidase activity
C2L62_RS18900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C2L62_RS18905	COG1321	iron dependent repressor
C2L62_RS18915	COG2194	sulfuric ester hydrolase activity
C2L62_RS18920	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C2L62_RS18935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2L62_RS18940	COG0765	amino acid transport
C2L62_RS18945	COG1126	abc transporter atp-binding protein
C2L62_RS18950	COG0668	transmembrane transport
C2L62_RS18960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C2L62_RS18970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2L62_RS18980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C2L62_RS18985	COG1199	ATP-dependent helicase activity
C2L62_RS18990	COG0513	Belongs to the DEAD box helicase family
C2L62_RS18995	COG3958	Transketolase
C2L62_RS19000	COG3959	Transketolase, thiamine diphosphate binding domain
C2L62_RS19005	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS19010	COG2271	Major facilitator Superfamily
C2L62_RS19015	COG0583	DNA-binding transcription factor activity
C2L62_RS19020	COG1309	transcriptional regulator
C2L62_RS19025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2L62_RS19030	COG1131	(ABC) transporter
C2L62_RS19035	COG0842	Transport permease protein
C2L62_RS19040	COG0842	Transport permease protein
C2L62_RS19050	COG3568	Endonuclease Exonuclease Phosphatase
C2L62_RS19055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2L62_RS19060	COG0392	lysyltransferase activity
C2L62_RS19070	COG0670	Belongs to the BI1 family
C2L62_RS19075	COG0314	molybdopterin synthase activity
C2L62_RS19080	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C2L62_RS19090	COG0521	Mo-molybdopterin cofactor biosynthetic process
C2L62_RS19115	COG0745	RESPONSE REGULATOR receiver
C2L62_RS19120	COG0642	Histidine kinase
C2L62_RS19155	COG2226	methyltransferase
C2L62_RS19170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C2L62_RS19175	COG1881	PFAM PEBP family protein
C2L62_RS19215	COG4677	pectinesterase activity
C2L62_RS19245	COG0789	Transcriptional regulator
C2L62_RS19250	COG2200	EAL domain
C2L62_RS19275	COG0561	phosphatase activity
C2L62_RS19280	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C2L62_RS19285	COG4149	molybdate abc transporter
C2L62_RS19290	COG0725	ABC transporter, periplasmic molybdate-binding protein
C2L62_RS19300	COG2005	Transcriptional regulator
C2L62_RS19300	COG3585	molybdate ion transport
C2L62_RS19305	COG1119	ATPase activity
C2L62_RS19315	COG1085	galactose-1-phosphate uridylyltransferase
C2L62_RS19325	COG2017	converts alpha-aldose to the beta-anomer
C2L62_RS19335	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C2L62_RS19350	COG3201	nicotinamide mononucleotide transporter
C2L62_RS19355	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C2L62_RS19395	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C2L62_RS19400	COG2885	chlorophyll binding
C2L62_RS19410	COG3064	Membrane
C2L62_RS19415	COG0848	biopolymer transport protein
C2L62_RS19420	COG0811	peptide transport
C2L62_RS19425	COG0824	Thioesterase
C2L62_RS19430	COG3790	cyd operon protein YbgE
C2L62_RS19435	COG4890	Cyd operon protein YbgT
C2L62_RS19440	COG1294	oxidase, subunit
C2L62_RS19445	COG1271	oxidase subunit
C2L62_RS19455	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C2L62_RS19470	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2L62_RS19475	COG0567	Dehydrogenase, E1 component
C2L62_RS19480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C2L62_RS19485	COG1053	succinate dehydrogenase
C2L62_RS19490	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C2L62_RS19495	COG2009	succinate dehydrogenase
C2L62_RS19530	COG1984	allophanate hydrolase subunit 2
C2L62_RS19535	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C2L62_RS19550	COG0415	Belongs to the DNA photolyase family
C2L62_RS19580	COG2205	protein histidine kinase activity
C2L62_RS19585	COG0745	RESPONSE REGULATOR receiver
C2L62_RS19595	COG0033	Phosphoglucomutase
C2L62_RS19605	COG0596	Alpha beta hydrolase
C2L62_RS19620	COG0735	belongs to the Fur family
C2L62_RS19660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C2L62_RS19665	COG1846	Transcriptional regulator
C2L62_RS19665	COG1940	carbohydrate kinase activity
C2L62_RS19670	COG0647	UMP catabolic process
C2L62_RS19675	COG0367	asparagine synthase
C2L62_RS19720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C2L62_RS19730	COG1702	phosphate starvation-inducible protein PhoH
C2L62_RS19740	COG4535	Mg2 and Co2 transporter CorC
C2L62_RS19755	COG0765	amino acid transport
C2L62_RS19760	COG0765	amino acid transport
C2L62_RS19765	COG1126	abc transporter atp-binding protein
C2L62_RS19780	COG2888	peptidyl-tyrosine sulfation
C2L62_RS19795	COG1466	dna polymerase III delta subunit
C2L62_RS19810	COG0799	negative regulation of ribosome biogenesis
C2L62_RS19820	COG0768	penicillin binding
C2L62_RS19825	COG0772	Belongs to the SEDS family
C2L62_RS19830	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C2L62_RS19835	COG1686	Belongs to the peptidase S11 family
C2L62_RS19850	COG0583	DNA-binding transcription factor activity
C2L62_RS19865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C2L62_RS19890	COG3069	C4-dicarboxylate transmembrane transporter activity
C2L62_RS19895	COG3719	Belongs to the RNase T2 family
C2L62_RS19900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C2L62_RS19920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C2L62_RS19925	COG0583	DNA-binding transcription factor activity
C2L62_RS19930	COG3969	phosphoadenosine phosphosulfate
C2L62_RS19935	COG1475	DNA binding
C2L62_RS19940	COG0436	Aminotransferase
C2L62_RS19965	COG1129	ABC transporter
C2L62_RS19970	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS19975	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS19985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C2L62_RS20000	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C2L62_RS20010	COG0402	S-adenosylhomocysteine deaminase activity
C2L62_RS20020	COG0483	inositol monophosphate 1-phosphatase activity
C2L62_RS20025	COG2271	Major facilitator Superfamily
C2L62_RS20055	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS20060	COG1129	ABC transporter
C2L62_RS20065	COG0371	Dehydrogenase
C2L62_RS20070	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS20085	COG2879	small protein
C2L62_RS20090	COG1966	Carbon starvation protein
C2L62_RS20100	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS20105	COG3433	isochorismatase activity
C2L62_RS20105	COG1535	isochorismatase
C2L62_RS20110	COG1021	2,3-dihydroxybenzoate-AMP ligase
C2L62_RS20115	COG1169	isochorismate synthase
C2L62_RS20120	COG4592	Periplasmic binding protein
C2L62_RS20130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2L62_RS20135	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2L62_RS20140	COG1120	ATPase activity
C2L62_RS20145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C2L62_RS20145	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C2L62_RS20150	COG3251	PFAM MbtH domain protein
C2L62_RS20155	COG2382	esterase
C2L62_RS20165	COG4771	TonB-dependent receptor
C2L62_RS20170	COG2977	Belongs to the P-Pant transferase superfamily
C2L62_RS20175	COG3958	Transketolase
C2L62_RS20180	COG3959	Transketolase, thiamine diphosphate binding domain
C2L62_RS20190	COG2390	Transcriptional regulator
C2L62_RS20195	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C2L62_RS20200	COG1879	ABC-type sugar transport system periplasmic component
C2L62_RS20210	COG1129	ABC transporter
C2L62_RS20225	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS20235	COG0583	DNA-binding transcription factor activity
C2L62_RS20240	COG0668	transmembrane transport
C2L62_RS20250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C2L62_RS20275	COG0747	negative chemotaxis
C2L62_RS20280	COG0601	transmembrane transport
C2L62_RS20285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2L62_RS20290	COG0444	Belongs to the ABC transporter superfamily
C2L62_RS20295	COG4608	Belongs to the ABC transporter superfamily
C2L62_RS20300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C2L62_RS20305	COG4221	oxidoreductase activity
C2L62_RS20315	COG4215	(ABC) transporter
C2L62_RS20320	COG0765	amino acid transport
C2L62_RS20325	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C2L62_RS20340	COG0697	spore germination
C2L62_RS20350	COG3698	Phosphodiester glycosidase
C2L62_RS20400	COG2315	Protein conserved in bacteria
C2L62_RS20405	COG0778	Nitroreductase
C2L62_RS20415	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2L62_RS20425	COG3716	PTS system mannose fructose sorbose family IID component
C2L62_RS20430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C2L62_RS20435	COG2222	sugar isomerase
C2L62_RS20440	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C2L62_RS20440	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C2L62_RS20460	COG0477	Major facilitator Superfamily
C2L62_RS20465	COG0668	transmembrane transport
C2L62_RS20495	COG3188	usher protein
C2L62_RS20510	COG2771	luxR family
C2L62_RS20520	COG0673	inositol 2-dehydrogenase activity
C2L62_RS20530	COG2211	Major facilitator Superfamily
C2L62_RS20535	COG1113	amino acid transport
C2L62_RS20550	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS20555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C2L62_RS20565	COG0531	amino acid
C2L62_RS20615	COG0667	Aldo Keto reductase
C2L62_RS20620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2L62_RS20625	COG1473	amidohydrolase
C2L62_RS20645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2L62_RS20650	COG1120	ATPase activity
C2L62_RS20655	COG1566	PFAM secretion protein HlyD family protein
C2L62_RS20710	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS20715	COG1129	ABC transporter
C2L62_RS20730	COG0673	inositol 2-dehydrogenase activity
C2L62_RS20760	COG3104	oligopeptide transport
C2L62_RS20765	COG1982	Orn Lys Arg decarboxylase major
C2L62_RS20770	COG0531	amino acid
C2L62_RS20775	COG3710	Transcriptional regulator
C2L62_RS20785	COG1560	Kdo2-lipid A biosynthetic process
C2L62_RS20800	COG3188	usher protein
C2L62_RS20805	COG3121	Chaperone
C2L62_RS20810	COG3539	Fimbrial protein
C2L62_RS20870	COG2501	S4 domain
C2L62_RS20880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C2L62_RS20895	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C2L62_RS20900	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C2L62_RS20915	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C2L62_RS20920	COG4181	ATPase activity
C2L62_RS20925	COG2755	lipolytic protein G-D-S-L family
C2L62_RS20930	COG0300	oxidoreductase activity
C2L62_RS20935	COG3118	belongs to the thioredoxin family
C2L62_RS20945	COG0390	transport system, permease component
C2L62_RS20950	COG4619	ABC transporter
C2L62_RS20955	COG0330	HflC and HflK could
C2L62_RS20960	COG1585	Membrane protein implicated in regulation of membrane protease activity
C2L62_RS20975	COG3735	TraB family
C2L62_RS20980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C2L62_RS20990	COG2223	nitrite transmembrane transporter activity
C2L62_RS20995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C2L62_RS20995	COG4651	solute:proton antiporter activity
C2L62_RS21000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2L62_RS21040	COG2832	Protein of unknown function (DUF454)
C2L62_RS21045	COG3923	Primosomal replication protein n
C2L62_RS21055	COG5464	transposase or invertase
C2L62_RS21060	COG3264	Mechanosensitive ion channel
C2L62_RS21060	COG1196	nuclear chromosome segregation
C2L62_RS21080	COG1309	transcriptional regulator
C2L62_RS21085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2L62_RS21090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2L62_RS21105	COG0110	maltose O-acetyltransferase activity
C2L62_RS21150	COG1874	Beta-galactosidase
C2L62_RS21155	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C2L62_RS21160	COG3833	ABC-type maltose transport systems, permease component
C2L62_RS21165	COG1175	transmembrane transport
C2L62_RS21170	COG2182	Extracellular solute-binding protein
C2L62_RS21180	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C2L62_RS21195	COG2364	Membrane
C2L62_RS21225	COG3695	enzyme binding
C2L62_RS21230	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C2L62_RS21235	COG1946	Acyl-CoA thioesterase
C2L62_RS21240	COG0004	ammonium transporteR
C2L62_RS21245	COG0347	Belongs to the P(II) protein family
C2L62_RS21250	COG1132	(ABC) transporter
C2L62_RS21255	COG1132	(ABC) transporter
C2L62_RS21260	COG1522	sequence-specific DNA binding
C2L62_RS21275	COG4533	DNA binding
C2L62_RS21285	COG0824	Thioesterase
C2L62_RS21290	COG1555	photosystem II stabilization
C2L62_RS21295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C2L62_RS21300	COG0776	regulation of translation
C2L62_RS21305	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C2L62_RS21335	COG0271	Belongs to the BolA IbaG family
C2L62_RS21340	COG3056	Lipoprotein
C2L62_RS21345	COG2223	nitrite transmembrane transporter activity
C2L62_RS21350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C2L62_RS21355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C2L62_RS21360	COG1845	cytochrome c oxidase, subunit III
C2L62_RS21365	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C2L62_RS21380	COG1414	Transcriptional regulator
C2L62_RS21385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C2L62_RS21390	COG1053	succinate dehydrogenase
C2L62_RS21400	COG1053	succinate dehydrogenase
C2L62_RS21415	COG0673	inositol 2-dehydrogenase activity
C2L62_RS21420	COG2814	Major facilitator Superfamily
C2L62_RS21430	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C2L62_RS21435	COG0693	protein deglycase activity
C2L62_RS21455	COG0142	geranyltranstransferase activity
C2L62_RS21465	COG0667	Aldo Keto reductase
C2L62_RS21470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C2L62_RS21490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C2L62_RS21490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C2L62_RS21500	COG4238	major outer membrane lipoprotein
C2L62_RS21520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C2L62_RS21525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C2L62_RS21530	COG1862	Preprotein translocase
C2L62_RS21550	COG0450	alkyl hydroperoxide reductase
C2L62_RS21555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS21570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2L62_RS21580	COG1228	amidohydrolase
C2L62_RS21590	COG1335	isochorismatase
C2L62_RS21595	COG0583	DNA-binding transcription factor activity
C2L62_RS21600	COG0366	Alpha amylase catalytic
C2L62_RS21625	COG0420	3'-5' exonuclease activity
C2L62_RS21630	COG0419	ATPase involved in DNA repair
C2L62_RS21635	COG1940	carbohydrate kinase activity
C2L62_RS21650	COG4126	flavin adenine dinucleotide binding
C2L62_RS21660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C2L62_RS21665	COG3416	Protein conserved in bacteria
C2L62_RS21675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C2L62_RS21685	COG1785	Belongs to the alkaline phosphatase family
C2L62_RS21725	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C2L62_RS21730	COG1335	isochorismatase
C2L62_RS21735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C2L62_RS21740	COG0113	porphobilinogen synthase activity
C2L62_RS21750	COG2175	clavaminate synthase activity
C2L62_RS21755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2L62_RS21760	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C2L62_RS21765	COG4521	taurine ABC transporter
C2L62_RS21770	COG2040	homocysteine
C2L62_RS21775	COG0833	amino acid
C2L62_RS21785	COG4303	Ethanolamine ammonia lyase large subunit
C2L62_RS21790	COG4302	ethanolamine ammonia-lyase activity
C2L62_RS21825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2L62_RS21830	COG1126	abc transporter atp-binding protein
C2L62_RS21835	COG0765	amino acid transport
C2L62_RS21840	COG0765	amino acid transport
C2L62_RS21855	COG3188	usher protein
C2L62_RS21880	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C2L62_RS21890	COG3639	organic phosphonate transmembrane transporter activity
C2L62_RS21925	COG0791	NLP P60 protein
C2L62_RS21950	COG0582	viral genome integration into host DNA
C2L62_RS21955	COG1192	Involved in chromosome partitioning
C2L62_RS22015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C2L62_RS22020	COG0022	dehydrogenase e1 component
C2L62_RS22025	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2L62_RS22030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2L62_RS22055	COG1070	Carbohydrate kinase
C2L62_RS22060	COG1028	Short-chain dehydrogenase reductase Sdr
C2L62_RS22065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C2L62_RS22070	COG3775	system Galactitol-specific IIC component
C2L62_RS22075	COG0625	glutathione transferase activity
C2L62_RS22080	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C2L62_RS22100	COG0579	oxidoreductase
C2L62_RS22105	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS22110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C2L62_RS22115	COG1113	amino acid transport
C2L62_RS22120	COG1802	Transcriptional regulator
C2L62_RS22140	COG2195	Cleaves the N-terminal amino acid of tripeptides
C2L62_RS22145	COG0454	-acetyltransferase
C2L62_RS22160	COG2991	Protein conserved in bacteria
C2L62_RS22175	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C2L62_RS22180	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C2L62_RS22200	COG3034	peptidoglycan biosynthetic process
C2L62_RS22205	COG0121	glutamine amidotransferase
C2L62_RS22215	COG1960	acyl-CoA dehydrogenase activity
C2L62_RS22220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C2L62_RS22230	COG0583	DNA-binding transcription factor activity
C2L62_RS22240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2L62_RS22250	COG2226	methyltransferase
C2L62_RS22260	COG0741	lytic transglycosylase activity
C2L62_RS22260	COG1388	LysM domain
C2L62_RS22265	COG2226	methyltransferase
C2L62_RS22275	COG2814	Major facilitator Superfamily
C2L62_RS22280	COG0583	DNA-binding transcription factor activity
C2L62_RS22285	COG0656	L-ascorbic acid biosynthetic process
C2L62_RS22320	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C2L62_RS22330	COG2011	ABC-type metal ion transport system permease component
C2L62_RS22335	COG1464	Belongs to the NlpA lipoprotein family
C2L62_RS22345	COG1720	tRNA m6t6A37 methyltransferase activity
C2L62_RS22355	COG0791	NLP P60 protein
C2L62_RS22360	COG3015	lipoprotein NlpE involved in copper resistance
C2L62_RS22365	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C2L62_RS22380	COG4568	rho-dependent transcription termination
C2L62_RS22390	COG0346	lactoylglutathione lyase activity
C2L62_RS22395	COG1982	Orn Lys Arg decarboxylase major
C2L62_RS22435	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C2L62_RS22445	COG0750	zinc metalloprotease
C2L62_RS22450	COG0575	Belongs to the CDS family
C2L62_RS22465	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C2L62_RS22490	COG0024	Methionine aminopeptidase
C2L62_RS22495	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C2L62_RS22510	COG3835	regulator
C2L62_RS22515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2L62_RS22535	COG2860	membrane
C2L62_RS22555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2L62_RS22560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2L62_RS22565	COG1120	ATPase activity
C2L62_RS22575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C2L62_RS22660	COG1643	Atp-dependent helicase
C2L62_RS22665	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C2L62_RS22685	COG0617	tRNA 3'-terminal CCA addition
C2L62_RS22690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C2L62_RS22710	COG0726	polysaccharide deacetylase
C2L62_RS22715	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS22720	COG0842	Transport permease protein
C2L62_RS22725	COG1131	(ABC) transporter
C2L62_RS22730	COG0288	reversible hydration of carbon dioxide
C2L62_RS22740	COG4993	Dehydrogenase
C2L62_RS22745	COG2132	Multicopper oxidase
C2L62_RS22800	COG3064	Membrane
C2L62_RS22815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2L62_RS22820	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2L62_RS22825	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C2L62_RS22830	COG2186	Transcriptional regulator
C2L62_RS22835	COG1113	amino acid transport
C2L62_RS22840	COG2211	Major facilitator Superfamily
C2L62_RS22845	COG3940	Belongs to the glycosyl hydrolase 43 family
C2L62_RS22850	COG3725	Membrane protein required for beta-lactamase induction
C2L62_RS22855	COG3023	N-Acetylmuramoyl-L-alanine amidase
C2L62_RS22865	COG4969	Belongs to the N-Me-Phe pilin family
C2L62_RS22870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C2L62_RS22875	COG1459	type II secretion system
C2L62_RS22900	COG0494	nUDIX hydrolase
C2L62_RS22920	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C2L62_RS22925	COG0849	cell division
C2L62_RS22950	COG0772	Belongs to the SEDS family
C2L62_RS22965	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C2L62_RS22970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C2L62_RS22975	COG0768	penicillin binding
C2L62_RS22995	COG1609	Transcriptional regulator
C2L62_RS23005	COG0028	Belongs to the TPP enzyme family
C2L62_RS23055	COG0738	Major facilitator superfamily
C2L62_RS23065	COG0583	DNA-binding transcription factor activity
C2L62_RS23070	COG2271	Major facilitator Superfamily
C2L62_RS23075	COG2814	Major facilitator Superfamily
C2L62_RS23095	COG1178	ABC-type Fe3 transport system permease component
C2L62_RS23105	COG0586	Pfam SNARE associated Golgi protein
C2L62_RS23125	COG0235	Class ii aldolase
C2L62_RS23130	COG0417	DNA replication proofreading
C2L62_RS23140	COG0564	pseudouridine synthase activity
C2L62_RS23155	COG3493	citrate carrier protein
C2L62_RS23170	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C2L62_RS23175	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C2L62_RS23185	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C2L62_RS23235	COG0505	Belongs to the CarA family
C2L62_RS23300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C2L62_RS23325	COG1047	Peptidyl-prolyl cis-trans
C2L62_RS23340	COG0196	riboflavin kinase activity
C2L62_RS23355	COG0583	DNA-binding transcription factor activity
C2L62_RS23380	COG4735	regulation of single-species biofilm formation
C2L62_RS23385	COG1584	GPR1 FUN34 yaaH family protein
C2L62_RS23390	COG0477	Major facilitator Superfamily
C2L62_RS23395	COG0521	Mo-molybdopterin cofactor biosynthetic process
C2L62_RS23400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C2L62_RS23405	COG1115	amino acid carrier protein
C2L62_RS23420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C2L62_RS23430	COG0460	homoserine dehydrogenase
C2L62_RS23430	COG0527	aspartate kinase activity
C2L62_RS23440	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C2L62_RS23450	COG0745	RESPONSE REGULATOR receiver
C2L62_RS23455	COG4452	Inner membrane protein CreD
C2L62_RS23460	COG2205	protein histidine kinase activity
C2L62_RS23465	COG0745	RESPONSE REGULATOR receiver
C2L62_RS23470	COG3045	CreA protein
C2L62_RS23475	COG2207	Transcriptional regulator
C2L62_RS23475	COG3708	Transcriptional regulator
C2L62_RS23495	COG0741	lytic transglycosylase activity
C2L62_RS23500	COG0488	(ABC) transporter
C2L62_RS23510	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C2L62_RS23515	COG0560	Phosphoserine phosphatase
C2L62_RS23525	COG3726	membrane protein affecting hemolysin expression
C2L62_RS23555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2L62_RS23560	COG0084	hydrolase, TatD family'
C2L62_RS23565	COG4667	esterase of the alpha-beta hydrolase superfamily
C2L62_RS23575	COG2823	Periplasmic or secreted lipoprotein
C2L62_RS23585	COG1011	Hydrolase
C2L62_RS23590	COG0456	acetyltransferase
C2L62_RS23595	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C2L62_RS23625	COG3706	GGDEF domain
C2L62_RS23630	COG4114	ferric iron reductase
C2L62_RS23635	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS23635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS23640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C2L62_RS23645	COG2197	response regulator
C2L62_RS23650	COG2197	response regulator
C2L62_RS23670	COG2966	Psort location CytoplasmicMembrane, score
C2L62_RS23685	COG1484	DNA-dependent DNA replication
C2L62_RS23700	COG5464	transposase or invertase
C2L62_RS23710	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C2L62_RS23715	COG3716	PTS system mannose fructose sorbose family IID component
C2L62_RS23720	COG3715	PTS system
C2L62_RS23735	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C2L62_RS23735	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C2L62_RS23745	COG1063	alcohol dehydrogenase
C2L62_RS23750	COG1802	Transcriptional regulator
C2L62_RS23755	COG2271	Major facilitator Superfamily
C2L62_RS23760	COG1214	PFAM Peptidase M22, glycoprotease
C2L62_RS23760	COG0456	acetyltransferase
C2L62_RS23770	COG1737	Transcriptional regulator
C2L62_RS23775	COG0800	Aldolase
C2L62_RS23780	COG3734	2-keto-3-deoxy-galactonokinase
C2L62_RS23795	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
C2L62_RS23825	COG1846	Transcriptional regulator
C2L62_RS23835	COG0179	Fumarylacetoacetate (FAA) hydrolase
C2L62_RS23845	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS23850	COG3384	dioxygenase
C2L62_RS23860	COG3971	2-oxopent-4-enoate hydratase activity
C2L62_RS23880	COG2368	4-hydroxyphenylacetate
C2L62_RS23885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C2L62_RS23900	COG1966	Carbon starvation protein
C2L62_RS23905	COG2879	small protein
C2L62_RS23910	COG0523	cobalamin synthesis protein
C2L62_RS23920	COG1012	belongs to the aldehyde dehydrogenase family
C2L62_RS23925	COG5464	transposase or invertase
C2L62_RS23930	COG1917	Cupin 2, conserved barrel domain protein
C2L62_RS23930	COG2207	Transcriptional regulator
C2L62_RS23940	COG2733	membrane
C2L62_RS23955	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C2L62_RS23960	COG1924	4 iron, 4 sulfur cluster binding
C2L62_RS23975	COG1566	PFAM secretion protein HlyD family protein
C2L62_RS23985	COG5457	Domain of unknown function (DUF1127)
C2L62_RS23990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2L62_RS24000	COG0583	DNA-binding transcription factor activity
C2L62_RS24005	COG2249	NAD(P)H dehydrogenase (quinone) activity
C2L62_RS24015	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS24020	COG1129	ABC transporter
C2L62_RS24025	COG1879	ABC-type sugar transport system periplasmic component
C2L62_RS24035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2L62_RS24040	COG0842	Transport permease protein
C2L62_RS24040	COG1129	ABC transporter
C2L62_RS24045	COG0842	Transport permease protein
C2L62_RS24075	COG2850	peptidyl-arginine hydroxylation
C2L62_RS24090	COG5002	protein histidine kinase activity
C2L62_RS24095	COG0745	RESPONSE REGULATOR receiver
C2L62_RS24105	COG1538	Outer membrane efflux protein
C2L62_RS24110	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2L62_RS24115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2L62_RS24120	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2L62_RS24130	COG3040	lipid binding
C2L62_RS24135	COG0789	Transcriptional regulator
C2L62_RS24145	COG0300	oxidoreductase activity
C2L62_RS24160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C2L62_RS24180	COG3272	Protein of unknown function (DUF1722)
C2L62_RS24185	COG4580	involved in the transport of maltose and maltodextrins
C2L62_RS24195	COG2211	Major facilitator Superfamily
C2L62_RS24200	COG3507	Belongs to the glycosyl hydrolase 43 family
C2L62_RS24315	COG3039	Transposase
C2L62_RS24325	COG0582	viral genome integration into host DNA
C2L62_RS24340	COG0288	reversible hydration of carbon dioxide
C2L62_RS24345	COG0659	secondary active sulfate transmembrane transporter activity
C2L62_RS24350	COG1064	alcohol dehydrogenase
C2L62_RS24355	COG1175	transmembrane transport
C2L62_RS24360	COG0395	ABC-type sugar transport system, permease component
C2L62_RS24365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C2L62_RS24370	COG3842	ATPase activity
C2L62_RS24375	COG1653	transport
C2L62_RS24385	COG1082	Xylose isomerase domain protein TIM barrel
C2L62_RS24395	COG3962	Belongs to the TPP enzyme family
C2L62_RS24400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2L62_RS24405	COG0837	glucose binding
C2L62_RS24405	COG1737	Transcriptional regulator
C2L62_RS24435	COG3718	enzyme involved in inositol metabolism
C2L62_RS24450	COG0433	COG0433 Predicted ATPase
C2L62_RS24455	COG0795	lipopolysaccharide-transporting ATPase activity
C2L62_RS24460	COG0795	lipopolysaccharide-transporting ATPase activity
C2L62_RS24475	COG2927	DNA polymerase III (CHI subunit)
C2L62_RS24480	COG0525	valine-tRNA ligase activity
C2L62_RS24505	COG2188	Transcriptional regulator
C2L62_RS24510	COG1288	antiporter activity
C2L62_RS24515	COG1228	amidohydrolase
C2L62_RS24520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2L62_RS24525	COG2222	sugar isomerase
C2L62_RS24530	COG2731	YhcH YjgK YiaL family protein
C2L62_RS24575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2L62_RS24575	COG1263	PTS System
C2L62_RS24580	COG0366	Alpha amylase catalytic
C2L62_RS24585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2L62_RS24590	COG1486	melibiose metabolic process
C2L62_RS24610	COG0602	queuosine metabolic process
C2L62_RS24615	COG2026	Addiction module toxin, RelE StbE family
C2L62_RS24620	COG3077	Addiction module antitoxin, RelB DinJ family
C2L62_RS24625	COG3711	transcriptional antiterminator
C2L62_RS24625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2L62_RS24630	COG2706	6-phosphogluconolactonase activity
C2L62_RS24645	COG3964	amidohydrolase
C2L62_RS24680	COG0312	modulator of DNA gyrase
C2L62_RS24700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C2L62_RS24710	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS24715	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS24720	COG1129	ABC transporter
C2L62_RS24725	COG1879	ABC-type sugar transport system periplasmic component
C2L62_RS24745	COG2105	PFAM AIG2 family protein
C2L62_RS24750	COG2911	Protein conserved in bacteria
C2L62_RS24755	COG0729	surface antigen
C2L62_RS24765	COG1253	flavin adenine dinucleotide binding
C2L62_RS24780	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C2L62_RS24795	COG1733	regulation of RNA biosynthetic process
C2L62_RS24800	COG0702	epimerase
C2L62_RS24810	COG0697	spore germination
C2L62_RS24820	COG1113	amino acid transport
C2L62_RS24825	COG0545	Peptidyl-prolyl cis-trans isomerase
C2L62_RS24830	COG3061	Opacity-associated protein A
C2L62_RS24840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C2L62_RS24845	COG2965	DNA replication, synthesis of RNA primer
C2L62_RS24905	COG1073	alpha beta
C2L62_RS24910	COG3650	response to hydrogen peroxide
C2L62_RS24920	COG1960	acyl-CoA dehydrogenase activity
C2L62_RS24925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2L62_RS24930	COG0557	exoribonuclease II activity
C2L62_RS24945	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C2L62_RS24955	COG0330	HflC and HflK could
C2L62_RS24960	COG0330	HflC and HflK could
C2L62_RS24965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C2L62_RS24985	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2L62_RS24990	COG0802	atpase or kinase
C2L62_RS24995	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C2L62_RS24995	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C2L62_RS25000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C2L62_RS25050	COG0629	single-stranded DNA binding
C2L62_RS25060	COG0270	DNA (cytosine-5-)-methyltransferase activity
C2L62_RS25250	COG2003	Belongs to the UPF0758 family
C2L62_RS25400	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C2L62_RS25400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C2L62_RS25405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C2L62_RS25410	COG1252	NADH dehydrogenase
C2L62_RS25415	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C2L62_RS25485	COG4372	Transposase
C2L62_RS25510	COG0583	DNA-binding transcription factor activity
C2L62_RS25525	COG0583	DNA-binding transcription factor activity
C2L62_RS25540	COG2837	iron assimilation
C2L62_RS25545	COG0582	viral genome integration into host DNA
C2L62_RS25570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2L62_RS25595	COG3264	Mechanosensitive ion channel
C2L62_RS25595	COG1511	domain protein
C2L62_RS25610	COG1053	succinate dehydrogenase
C2L62_RS25615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C2L62_RS25635	COG2076	Multidrug Resistance protein
C2L62_RS25640	COG5510	response to toxic substance
C2L62_RS25655	COG1509	lysine 2,3-aminomutase activity
C2L62_RS25725	COG0531	amino acid
C2L62_RS25730	COG3030	protein affecting phage T7 exclusion by the F plasmid
C2L62_RS25740	COG1027	Aspartate ammonia-lyase
C2L62_RS25745	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C2L62_RS25760	COG1309	transcriptional regulator
C2L62_RS25790	COG0457	Tetratricopeptide repeat
C2L62_RS25795	COG1649	PFAM Uncharacterised BCR, COG1649
C2L62_RS25795	COG0726	polysaccharide deacetylase
C2L62_RS25800	COG1215	transferase activity, transferring glycosyl groups
C2L62_RS25820	COG0861	Integral membrane protein TerC family
C2L62_RS25855	COG1486	melibiose metabolic process
C2L62_RS25865	COG2169	Transcriptional regulator
C2L62_RS25880	COG2824	Alkylphosphonate utilization operon protein PhnA
C2L62_RS25885	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C2L62_RS25890	COG2188	Transcriptional regulator
C2L62_RS25895	COG3624	Phosphonate C-P lyase system protein PhnG
C2L62_RS25900	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
C2L62_RS25905	COG3626	phosphonate metabolism
C2L62_RS25910	COG3627	carbon phosphorus lyase activity
C2L62_RS25915	COG4107	phosphonate C-P lyase system protein PhnK
C2L62_RS25920	COG4778	phosphonate C-P lyase system protein PhnL
C2L62_RS25925	COG3454	Phosphonate metabolism
C2L62_RS25935	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C2L62_RS25945	COG4191	Histidine kinase
C2L62_RS25945	COG0784	Response regulator, receiver
C2L62_RS25950	COG1129	ABC transporter
C2L62_RS25955	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS25990	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C2L62_RS25995	COG1301	dicarboxylic acid transport
C2L62_RS26005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C2L62_RS26015	COG3162	membrane
C2L62_RS26045	COG3539	Fimbrial protein
C2L62_RS26050	COG1346	cytolysis
C2L62_RS26055	COG1380	Effector of murein hydrolase LrgA
C2L62_RS26060	COG0583	DNA-binding transcription factor activity
C2L62_RS26065	COG0025	NhaP-type Na H and K H
C2L62_RS26070	COG2252	PERMEase
C2L62_RS26075	COG0625	glutathione transferase activity
C2L62_RS26080	COG0789	Transcriptional regulator
C2L62_RS26090	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C2L62_RS26125	COG1234	tRNA 3'-trailer cleavage
C2L62_RS26130	COG1609	Transcriptional regulator
C2L62_RS26135	COG0483	inositol monophosphate 1-phosphatase activity
C2L62_RS26150	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2L62_RS26170	COG4771	TonB-dependent receptor
C2L62_RS26175	COG0741	lytic transglycosylase activity
C2L62_RS26195	COG2315	Protein conserved in bacteria
C2L62_RS26200	COG0432	Pfam Uncharacterised protein family UPF0047
C2L62_RS26215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C2L62_RS26220	COG0305	Participates in initiation and elongation during chromosome replication
C2L62_RS26235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C2L62_RS26245	COG0735	belongs to the Fur family
C2L62_RS26250	COG3237	CsbD-like
C2L62_RS26255	COG0534	Mate efflux family protein
C2L62_RS26265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C2L62_RS26340	COG0251	oxidation-reduction process
C2L62_RS26350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C2L62_RS26370	COG0527	aspartate kinase activity
C2L62_RS26425	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C2L62_RS26455	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C2L62_RS26465	COG0456	acetyltransferase
C2L62_RS26500	COG0151	Belongs to the GarS family
C2L62_RS26510	COG4191	Histidine kinase
C2L62_RS26515	COG3678	ATP-independent chaperone mediated protein folding
C2L62_RS26550	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C2L62_RS26565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C2L62_RS26570	COG2104	thiamine diphosphate biosynthetic process
C2L62_RS26585	COG3706	GGDEF domain
C2L62_RS26595	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2L62_RS26600	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C2L62_RS26635	COG0250	Participates in transcription elongation, termination and antitermination
C2L62_RS26685	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C2L62_RS26715	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C2L62_RS26725	COG1739	Uncharacterized protein family UPF0029
C2L62_RS26770	COG0805	protein transport
C2L62_RS26790	COG3165	ubiquinone biosynthetic process from chorismate
C2L62_RS26820	COG0583	DNA-binding transcription factor activity
C2L62_RS26825	COG0697	spore germination
C2L62_RS26830	COG0561	phosphatase activity
C2L62_RS26835	COG2267	carboxylic ester hydrolase activity
C2L62_RS26840	COG1280	lysine exporter protein (LysE YggA)
C2L62_RS26850	COG1280	lysine exporter protein (LysE YggA)
C2L62_RS26885	COG0210	DNA helicase
C2L62_RS26890	COG1011	Hydrolase
C2L62_RS26920	COG3072	Adenylate cyclase
C2L62_RS26935	COG2959	enzyme of heme biosynthesis
C2L62_RS26940	COG3071	HemY protein
C2L62_RS26985	COG2244	polysaccharide biosynthetic process
C2L62_RS26990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C2L62_RS26995	COG0456	acetyltransferase
C2L62_RS27000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C2L62_RS27005	COG1088	dTDP-glucose 4,6-dehydratase activity
C2L62_RS27010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C2L62_RS27015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C2L62_RS27025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C2L62_RS27030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C2L62_RS27040	COG3118	belongs to the thioredoxin family
C2L62_RS27070	COG1811	Na channel or pump
C2L62_RS27080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C2L62_RS27085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C2L62_RS27095	COG0583	DNA-binding transcription factor activity
C2L62_RS27100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C2L62_RS27115	COG3978	acetolactate synthase activity
C2L62_RS27135	COG3085	chromosome segregation
C2L62_RS27210	COG0583	DNA-binding transcription factor activity
C2L62_RS27235	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C2L62_RS27250	COG3443	Belongs to the bacterial solute-binding protein 9 family
C2L62_RS27255	COG2207	Transcriptional regulator
C2L62_RS27265	COG0371	Dehydrogenase
C2L62_RS27270	COG0697	spore germination
C2L62_RS27280	COG0583	DNA-binding transcription factor activity
C2L62_RS27290	COG0737	Belongs to the 5'-nucleotidase family
C2L62_RS27300	COG0527	aspartate kinase activity
C2L62_RS27300	COG0460	homoserine dehydrogenase
C2L62_RS27305	COG0626	cystathionine gamma-synthase activity
C2L62_RS27320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C2L62_RS27325	COG1609	Transcriptional regulator
C2L62_RS27330	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C2L62_RS27345	COG1575	Belongs to the MenA family. Type 1 subfamily
C2L62_RS27365	COG3678	ATP-independent chaperone mediated protein folding
C2L62_RS27370	COG0745	RESPONSE REGULATOR receiver
C2L62_RS27375	COG2205	protein histidine kinase activity
C2L62_RS27380	COG2258	MOSC domain
C2L62_RS27385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C2L62_RS27430	COG1129	ABC transporter
C2L62_RS27435	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS27440	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS27445	COG1454	alcohol dehydrogenase
C2L62_RS27455	COG2211	Major facilitator Superfamily
C2L62_RS27515	COG0205	6-phosphofructokinase activity
C2L62_RS27530	COG3383	formate dehydrogenase (NAD+) activity
C2L62_RS27530	COG0243	molybdopterin cofactor binding
C2L62_RS27535	COG0243	molybdopterin cofactor binding
C2L62_RS27535	COG3383	formate dehydrogenase (NAD+) activity
C2L62_RS27540	COG0437	4 iron, 4 sulfur cluster binding
C2L62_RS27545	COG2864	formate dehydrogenase
C2L62_RS27560	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C2L62_RS27565	COG0657	acetylesterase activity
C2L62_RS27570	COG0456	acetyltransferase
C2L62_RS27585	COG1011	Hydrolase
C2L62_RS27600	COG3852	Histidine kinase
C2L62_RS27610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C2L62_RS27640	COG0204	Acyl-transferase
C2L62_RS27650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C2L62_RS27655	COG3084	Protein conserved in bacteria
C2L62_RS27665	COG1763	Mo-molybdopterin cofactor biosynthetic process
C2L62_RS27695	COG2186	Transcriptional regulator
C2L62_RS27700	COG0477	Major facilitator Superfamily
C2L62_RS27705	COG1609	Transcriptional regulator
C2L62_RS27710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2L62_RS27720	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2L62_RS27725	COG1129	ABC transporter
C2L62_RS27755	COG1522	sequence-specific DNA binding
C2L62_RS27760	COG0716	FMN binding
C2L62_RS27775	COG3312	ion transport
C2L62_RS27830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C2L62_RS27835	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C2L62_RS27840	COG0573	inorganic phosphate transmembrane transporter activity
C2L62_RS27845	COG0581	inorganic phosphate transmembrane transporter activity
C2L62_RS27850	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C2L62_RS27855	COG0704	Plays a role in the regulation of phosphate uptake
C2L62_RS27870	COG2382	esterase
C2L62_RS27875	COG0363	glucosamine-6-phosphate deaminase activity
C2L62_RS27880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2L62_RS27890	COG2252	PERMEase
C2L62_RS27895	COG0431	NADPH-dependent FMN reductase
C2L62_RS27930	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C2L62_RS27990	COG3039	Transposase
C2L62_RS28090	COG3039	Transposase
C2L62_RS28150	COG2135	peptidase activity
C2L62_RS28305	COG1349	DNA-binding transcription factor activity
C2L62_RS28315	COG2084	Dehydrogenase
C2L62_RS28345	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C2L62_RS28585	COG2084	Dehydrogenase
C2L62_RS28595	COG1349	DNA-binding transcription factor activity
C2L62_RS28695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C2L62_RS28700	COG1475	DNA binding
C2L62_RS28705	COG1475	DNA binding
C2L62_RS28845	COG0328	RNA-DNA hybrid ribonuclease activity
C2L62_RS28880	COG0237	dephospho-CoA kinase activity
C2L62_RS28895	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C2L62_RS28905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C2L62_RS28910	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C2L62_RS29000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C2L62_RS29010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C2L62_RS29080	COG3344	reverse transcriptase
C2L62_RS29100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C2L62_RS29110	COG1702	phosphate starvation-inducible protein PhoH
C2L62_RS29230	COG3941	tape measure
C2L62_RS29510	COG5499	transcription regulator containing HTH domain
C2L62_RS29570	COG3344	reverse transcriptase
C2L62_RS29635	COG2199	diguanylate cyclase activity
C2L62_RS29635	COG2203	Gaf domain
C2L62_RS29640	COG1716	ATPase activity
C2L62_RS29640	COG5001	Diguanylate cyclase
C2L62_RS29660	COG4943	cyclic-guanylate-specific phosphodiesterase activity