locus-tag	class	description
CW753_RS00035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CW753_RS00055	COG0583	DNA-binding transcription factor activity
CW753_RS00060	COG2363	Small membrane protein
CW753_RS00070	COG1349	DNA-binding transcription factor activity
CW753_RS00095	COG0235	Class ii aldolase
CW753_RS00100	COG1454	alcohol dehydrogenase
CW753_RS00115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CW753_RS00130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CW753_RS00135	COG2011	ABC-type metal ion transport system permease component
CW753_RS00140	COG1464	Belongs to the NlpA lipoprotein family
CW753_RS00150	COG0477	Major facilitator Superfamily
CW753_RS00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CW753_RS00165	COG1760	l-serine dehydratase
CW753_RS00170	COG0814	amino acid
CW753_RS00175	COG1611	Belongs to the LOG family
CW753_RS00190	COG3098	single-species biofilm formation
CW753_RS00195	COG0564	pseudouridine synthase activity
CW753_RS00200	COG0716	FMN binding
CW753_RS00205	COG2271	Major facilitator Superfamily
CW753_RS00210	COG4948	Mandelate Racemase Muconate Lactonizing
CW753_RS00215	COG4948	Mandelate Racemase Muconate Lactonizing
CW753_RS00220	COG1929	Belongs to the glycerate kinase type-1 family
CW753_RS00230	COG3850	Histidine kinase
CW753_RS00230	COG3437	response regulator, receiver
CW753_RS00230	COG2205	protein histidine kinase activity
CW753_RS00230	COG4999	Histidine kinase
CW753_RS00240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CW753_RS00245	COG3956	TIGRFAM MazG family protein
CW753_RS00265	COG0602	queuosine metabolic process
CW753_RS00270	COG0720	synthase
CW753_RS00305	COG1857	crispr-associated protein
CW753_RS00320	COG1518	maintenance of DNA repeat elements
CW753_RS00325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CW753_RS00340	COG2234	aminopeptidase activity
CW753_RS00400	COG4942	peptidase
CW753_RS00400	COG1388	LysM domain
CW753_RS00405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CW753_RS00430	COG0163	prenyltransferase activity
CW753_RS00435	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CW753_RS00480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CW753_RS00485	COG4558	Periplasmic binding protein
CW753_RS00490	COG3720	iron ion transport
CW753_RS00510	COG0679	Auxin Efflux Carrier
CW753_RS00525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CW753_RS00530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CW753_RS00535	COG1121	(ABC) transporter
CW753_RS00545	COG1609	Transcriptional regulator
CW753_RS00550	COG1940	carbohydrate kinase activity
CW753_RS00555	COG1447	Phosphotransferase system cellobiose-specific component IIA
CW753_RS00560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CW753_RS00565	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CW753_RS00570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CW753_RS00580	COG4580	involved in the transport of maltose and maltodextrins
CW753_RS00590	COG2723	6-phospho-beta-galactosidase activity
CW753_RS00600	COG0309	Hydrogenase expression formation protein (HypE)
CW753_RS00605	COG0409	Hydrogenase expression formation protein
CW753_RS00610	COG0298	carbon dioxide binding
CW753_RS00615	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CW753_RS00635	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CW753_RS00640	COG0651	ATP synthesis coupled electron transport
CW753_RS00645	COG0650	Formate hydrogenlyase subunit 4
CW753_RS00650	COG3261	NADH dehydrogenase
CW753_RS00650	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CW753_RS00655	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CW753_RS00660	COG3260	NADH ubiquinone oxidoreductase 20
CW753_RS00670	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CW753_RS00680	COG2723	6-phospho-beta-galactosidase activity
CW753_RS00685	COG1263	PTS System
CW753_RS00685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CW753_RS00690	COG1609	Transcriptional regulator
CW753_RS00695	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CW753_RS00705	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CW753_RS00735	COG1349	DNA-binding transcription factor activity
CW753_RS00740	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CW753_RS00745	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS00755	COG3732	PTS system glucitol sorbitol-specific
CW753_RS00760	COG3730	PTS system glucitol sorbitol-specific
CW753_RS00765	COG2951	lytic endotransglycosylase activity
CW753_RS00775	COG1121	(ABC) transporter
CW753_RS00780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CW753_RS00785	COG0803	Belongs to the bacterial solute-binding protein 9 family
CW753_RS00790	COG1546	Belongs to the CinA family
CW753_RS00815	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CW753_RS00845	COG2823	Periplasmic or secreted lipoprotein
CW753_RS00850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CW753_RS00855	COG1238	metal cluster binding
CW753_RS00875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CW753_RS00880	COG2814	Major facilitator Superfamily
CW753_RS00885	COG1566	PFAM secretion protein HlyD family protein
CW753_RS00890	COG1846	Transcriptional regulator
CW753_RS00900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CW753_RS00910	COG4176	ABC-type proline glycine betaine transport system permease component
CW753_RS00925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CW753_RS00935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CW753_RS00940	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CW753_RS00950	COG4575	ribosome binding
CW753_RS00975	COG2916	Histone family protein nucleoid-structuring protein H-NS
CW753_RS00990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CW753_RS00995	COG0640	Transcriptional regulator
CW753_RS01005	COG0583	DNA-binding transcription factor activity
CW753_RS01010	COG3284	Transcriptional regulator
CW753_RS01020	COG3539	Fimbrial protein
CW753_RS01025	COG3121	Chaperone
CW753_RS01060	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS01070	COG0235	Class ii aldolase
CW753_RS01080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CW753_RS01115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CW753_RS01120	COG3708	Transcriptional regulator
CW753_RS01120	COG2207	Transcriptional regulator
CW753_RS01190	COG0582	viral genome integration into host DNA
CW753_RS01205	COG2867	negative regulation of translational initiation
CW753_RS01220	COG0497	DNA recombination
CW753_RS01240	COG4536	flavin adenine dinucleotide binding
CW753_RS01245	COG4137	Cytochrome C assembly protein
CW753_RS01250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CW753_RS01285	COG2885	chlorophyll binding
CW753_RS01290	COG2199	diguanylate cyclase activity
CW753_RS01300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CW753_RS01305	COG0287	Prephenate dehydrogenase
CW753_RS01305	COG1605	Chorismate mutase
CW753_RS01315	COG0077	Prephenate dehydratase
CW753_RS01315	COG1605	Chorismate mutase
CW753_RS01325	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CW753_RS01330	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CW753_RS01345	COG0542	response to heat
CW753_RS01370	COG0477	Major facilitator Superfamily
CW753_RS01375	COG5544	Lipoprotein
CW753_RS01380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CW753_RS01390	COG3148	PFAM DTW domain containing protein
CW753_RS01395	COG3118	belongs to the thioredoxin family
CW753_RS01400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CW753_RS01415	COG0513	Belongs to the DEAD box helicase family
CW753_RS01425	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CW753_RS01440	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CW753_RS01445	COG3026	antisigma factor binding
CW753_RS01450	COG3086	response to oxidative stress
CW753_RS01460	COG0681	Belongs to the peptidase S26 family
CW753_RS01480	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CW753_RS01490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CW753_RS01495	COG1737	Transcriptional regulator
CW753_RS01500	COG0560	Phosphoserine phosphatase
CW753_RS01515	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CW753_RS01515	COG0047	phosphoribosylformylglycinamidine synthase activity
CW753_RS01525	COG2205	protein histidine kinase activity
CW753_RS01530	COG3170	Tfp pilus assembly protein FimV
CW753_RS01535	COG2204	response regulator
CW753_RS01540	COG0347	Belongs to the P(II) protein family
CW753_RS01545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CW753_RS01545	COG1017	nitric oxide dioxygenase activity
CW753_RS01555	COG2259	Doxx family
CW753_RS01560	COG1940	carbohydrate kinase activity
CW753_RS01565	COG0457	Tetratricopeptide repeat
CW753_RS01570	COG0477	Major facilitator Superfamily
CW753_RS01570	COG2814	Major facilitator Superfamily
CW753_RS01575	COG2017	converts alpha-aldose to the beta-anomer
CW753_RS01580	COG2814	Major facilitator Superfamily
CW753_RS01585	COG3711	transcriptional antiterminator
CW753_RS01590	COG3683	transport system, periplasmic component
CW753_RS01595	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CW753_RS01625	COG0822	iron-sulfur transferase activity
CW753_RS01645	COG0633	Ferredoxin
CW753_RS01650	COG2975	iron-sulfur cluster assembly
CW753_RS01670	COG2897	thiosulfate sulfurtransferase activity
CW753_RS01675	COG2373	Large extracellular alpha-helical protein
CW753_RS01680	COG4953	penicillin-binding protein 1C
CW753_RS01715	COG2976	Protein conserved in bacteria
CW753_RS01735	COG1645	bacterial-type flagellum-dependent swarming motility
CW753_RS01745	COG0516	GMP reductase activity
CW753_RS01745	COG0517	IMP dehydrogenase activity
CW753_RS01755	COG3119	arylsulfatase activity
CW753_RS01760	COG0641	radical SAM
CW753_RS01780	COG2200	EAL domain
CW753_RS01795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CW753_RS01810	COG2723	6-phospho-beta-galactosidase activity
CW753_RS01820	COG2233	PERMEase
CW753_RS01835	COG1393	Belongs to the ArsC family
CW753_RS01840	COG4783	chaperone-mediated protein folding
CW753_RS01845	COG0628	permease
CW753_RS01850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CW753_RS01855	COG2716	regulation of RNA biosynthetic process
CW753_RS01865	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CW753_RS01875	COG2321	neutral zinc metallopeptidase
CW753_RS01880	COG1444	tRNA N-acetyltransferase activity
CW753_RS01885	COG0400	carboxylic ester hydrolase activity
CW753_RS01900	COG1393	Belongs to the ArsC family
CW753_RS01910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CW753_RS01920	COG0493	'glutamate synthase
CW753_RS01920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CW753_RS01930	COG5342	invasion associated locus B
CW753_RS01935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CW753_RS01940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CW753_RS01950	COG4810	utilization protein
CW753_RS02040	COG0860	N-Acetylmuramoyl-L-alanine amidase
CW753_RS02060	COG2837	iron assimilation
CW753_RS02070	COG4150	thiosulfate binding
CW753_RS02075	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CW753_RS02080	COG4208	sulfate ABC transporter
CW753_RS02085	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CW753_RS02095	COG4319	ketosteroid isomerase
CW753_RS02130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CW753_RS02150	COG3530	Putative quorum-sensing-regulated virulence factor
CW753_RS02155	COG0385	Bile acid
CW753_RS02160	COG0583	DNA-binding transcription factor activity
CW753_RS02195	COG3415	Transposase
CW753_RS02200	COG3415	Transposase
CW753_RS02220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CW753_RS02235	COG0667	Aldo Keto reductase
CW753_RS02240	COG3961	Belongs to the TPP enzyme family
CW753_RS02255	COG3279	Response regulator of the LytR AlgR family
CW753_RS02260	COG3275	phosphorelay sensor kinase activity
CW753_RS02270	COG0436	Aminotransferase
CW753_RS02280	COG2807	transmembrane transport
CW753_RS02290	COG0583	DNA-binding transcription factor activity
CW753_RS02345	COG0582	viral genome integration into host DNA
CW753_RS02355	COG2116	formate transmembrane transporter activity
CW753_RS02360	COG2853	Lipoprotein
CW753_RS02370	COG3691	Protein conserved in bacteria
CW753_RS02385	COG2062	phosphohistidine phosphatase, SixA
CW753_RS02410	COG0730	response to heat
CW753_RS02415	COG3101	peptidyl-lysine hydroxylation
CW753_RS02430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CW753_RS02450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CW753_RS02460	COG0586	Pfam SNARE associated Golgi protein
CW753_RS02475	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CW753_RS02480	COG1286	toxin biosynthetic process
CW753_RS02485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CW753_RS02490	COG0163	prenyltransferase activity
CW753_RS02510	COG4160	amino acid transport
CW753_RS02515	COG4598	ABC transporter
CW753_RS02525	COG1090	epimerase
CW753_RS02530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CW753_RS02535	COG0625	glutathione transferase activity
CW753_RS02540	COG0625	glutathione transferase activity
CW753_RS02545	COG0622	Phosphoesterase
CW753_RS02550	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CW753_RS02555	COG0857	belongs to the CobB CobQ family
CW753_RS02555	COG0280	phosphate acetyltransferase
CW753_RS02580	COG0471	metal ion transport
CW753_RS02580	COG0490	domain, Protein
CW753_RS02645	COG0839	Belongs to the complex I subunit 6 family
CW753_RS02660	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CW753_RS02675	COG2153	protein acetylation
CW753_RS02680	COG1169	isochorismate synthase
CW753_RS02705	COG0318	PFAM AMP-dependent synthetase and ligase
CW753_RS02715	COG5464	transposase or invertase
CW753_RS02735	COG1414	Transcriptional regulator
CW753_RS02745	COG2271	Major facilitator Superfamily
CW753_RS02755	COG0247	lactate metabolic process
CW753_RS02770	COG2271	Major facilitator Superfamily
CW753_RS02775	COG0584	glycerophosphoryl diester phosphodiesterase
CW753_RS02785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CW753_RS02815	COG0784	Response regulator, receiver
CW753_RS02815	COG2205	protein histidine kinase activity
CW753_RS02825	COG2198	Histidine kinase
CW753_RS02825	COG0642	Histidine kinase
CW753_RS02840	COG2169	Transcriptional regulator
CW753_RS02840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CW753_RS02845	COG3145	DNA-N1-methyladenine dioxygenase activity
CW753_RS02850	COG4615	Cyclic peptide transporter
CW753_RS02855	COG2239	Acts as a magnesium transporter
CW753_RS02860	COG0659	secondary active sulfate transmembrane transporter activity
CW753_RS02875	COG0628	permease
CW753_RS02900	COG1349	DNA-binding transcription factor activity
CW753_RS02905	COG0494	nUDIX hydrolase
CW753_RS02925	COG1061	Type III restriction enzyme res subunit
CW753_RS02935	COG2814	Major facilitator Superfamily
CW753_RS02945	COG4172	Belongs to the ABC transporter superfamily
CW753_RS02950	COG4239	(ABC) transporter, permease
CW753_RS02955	COG4174	ABC transporter (Permease)
CW753_RS02960	COG4166	transmembrane transport
CW753_RS02965	COG2200	EAL domain
CW753_RS02970	COG0791	NLP P60 protein
CW753_RS02975	COG0671	phosphoesterase, PA-phosphatase related
CW753_RS02980	COG0523	cobalamin synthesis protein
CW753_RS02985	COG0246	Mannitol dehydrogenase
CW753_RS02990	COG1312	Catalyzes the dehydration of D-mannonate
CW753_RS03015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CW753_RS03015	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CW753_RS03020	COG1105	Belongs to the carbohydrate kinase PfkB family
CW753_RS03035	COG2855	membrane
CW753_RS03045	COG0583	DNA-binding transcription factor activity
CW753_RS03050	COG0833	amino acid
CW753_RS03095	COG1129	ABC transporter
CW753_RS03105	COG2949	membrane
CW753_RS03115	COG1346	cytolysis
CW753_RS03125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CW753_RS03130	COG3659	wide pore channel activity
CW753_RS03145	COG2723	6-phospho-beta-galactosidase activity
CW753_RS03155	COG1538	Outer membrane efflux protein
CW753_RS03160	COG0586	Pfam SNARE associated Golgi protein
CW753_RS03170	COG1686	Belongs to the peptidase S11 family
CW753_RS03180	COG0277	FAD linked oxidase domain protein
CW753_RS03185	COG1472	Belongs to the glycosyl hydrolase 3 family
CW753_RS03190	COG1732	Glycine betaine
CW753_RS03195	COG1174	glycine betaine transport
CW753_RS03205	COG1174	glycine betaine transport
CW753_RS03215	COG3275	phosphorelay sensor kinase activity
CW753_RS03225	COG4807	Protein conserved in bacteria
CW753_RS03245	COG5455	response to cobalt ion
CW753_RS03250	COG0583	DNA-binding transcription factor activity
CW753_RS03255	COG2252	PERMEase
CW753_RS03265	COG0583	DNA-binding transcription factor activity
CW753_RS03285	COG0351	phosphomethylpyrimidine kinase
CW753_RS03290	COG1830	Aldolase
CW753_RS03300	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CW753_RS03335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CW753_RS03345	COG0747	negative chemotaxis
CW753_RS03350	COG0601	transmembrane transport
CW753_RS03355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CW753_RS03360	COG0444	Belongs to the ABC transporter superfamily
CW753_RS03365	COG4608	Belongs to the ABC transporter superfamily
CW753_RS03375	COG0826	peptidase U32
CW753_RS03380	COG0745	RESPONSE REGULATOR receiver
CW753_RS03385	COG2205	protein histidine kinase activity
CW753_RS03410	COG1301	dicarboxylic acid transport
CW753_RS03430	COG0443	Heat shock 70 kDa protein
CW753_RS03435	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CW753_RS03450	COG2982	Protein involved in outer membrane biogenesis
CW753_RS03455	COG1253	flavin adenine dinucleotide binding
CW753_RS03535	COG3039	Transposase
CW753_RS03580	COG3039	Transposase
CW753_RS03605	COG3039	Transposase
CW753_RS03645	COG0438	transferase activity, transferring glycosyl groups
CW753_RS03650	COG1442	glycosyl transferase family 8
CW753_RS03650	COG1216	Glycosyl transferase, family 2
CW753_RS03680	COG0463	Glycosyl transferase, family 2
CW753_RS03710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CW753_RS03740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CW753_RS03745	COG0583	DNA-binding transcription factor activity
CW753_RS03755	COG0531	amino acid
CW753_RS03760	COG0640	Transcriptional regulator
CW753_RS03765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CW753_RS03770	COG2925	Exonuclease
CW753_RS03790	COG1289	transmembrane transporter activity
CW753_RS03810	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CW753_RS03820	COG1942	4-Oxalocrotonate Tautomerase
CW753_RS03825	COG0583	DNA-binding transcription factor activity
CW753_RS03835	COG0477	Major facilitator Superfamily
CW753_RS03850	COG3300	MHYT domain
CW753_RS03850	COG5001	Diguanylate cyclase
CW753_RS03915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CW753_RS03935	COG0604	alcohol dehydrogenase
CW753_RS03940	COG1309	transcriptional regulator
CW753_RS03945	COG0025	NhaP-type Na H and K H
CW753_RS04010	COG1418	mRNA catabolic process
CW753_RS04015	COG0270	DNA (cytosine-5-)-methyltransferase activity
CW753_RS04020	COG3727	T/G mismatch-specific endonuclease activity
CW753_RS04025	COG0697	spore germination
CW753_RS04030	COG2354	Protein conserved in bacteria
CW753_RS04060	COG0366	Alpha amylase catalytic
CW753_RS04065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CW753_RS04075	COG0765	amino acid transport
CW753_RS04080	COG1126	abc transporter atp-binding protein
CW753_RS04085	COG2197	response regulator
CW753_RS04095	COG2197	response regulator
CW753_RS04135	COG3318	Belongs to the UPF0149 family
CW753_RS04135	COG3012	SEC-C Motif Domain Protein
CW753_RS04150	COG1528	Iron-storage protein
CW753_RS04165	COG0477	Major facilitator Superfamily
CW753_RS04175	COG2211	Major facilitator Superfamily
CW753_RS04185	COG1528	Iron-storage protein
CW753_RS04195	COG1879	ABC-type sugar transport system periplasmic component
CW753_RS04205	COG1172	Belongs to the binding-protein-dependent transport system permease family
CW753_RS04230	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CW753_RS04240	COG3102	Protein conserved in bacteria
CW753_RS04260	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CW753_RS04265	COG1801	Protein of unknown function DUF72
CW753_RS04270	COG1335	isochorismatase
CW753_RS04280	COG0494	nUDIX hydrolase
CW753_RS04305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CW753_RS04315	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CW753_RS04320	COG0739	heme binding
CW753_RS04325	COG1560	Kdo2-lipid A biosynthetic process
CW753_RS04350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CW753_RS04355	COG0129	dihydroxy-acid dehydratase activity
CW753_RS04360	COG0800	Aldolase
CW753_RS04370	COG3141	response to X-ray
CW753_RS04375	COG2979	Protein of unknown function (DUF533)
CW753_RS04380	COG1770	oligopeptidase
CW753_RS04385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CW753_RS04395	COG2372	response to copper ion
CW753_RS04400	COG1276	copper resistance
CW753_RS04415	COG2990	Protein conserved in bacteria
CW753_RS04440	COG3008	intermembrane lipid transfer
CW753_RS04445	COG2995	paraquat-inducible protein a
CW753_RS04450	COG1956	GAF domain-containing protein
CW753_RS04470	COG2814	Major facilitator Superfamily
CW753_RS04480	COG1414	Transcriptional regulator
CW753_RS04520	COG0768	penicillin binding
CW753_RS04525	COG2226	methyltransferase
CW753_RS04540	COG3716	PTS system mannose fructose sorbose family IID component
CW753_RS04545	COG3715	PTS system
CW753_RS04550	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CW753_RS04550	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CW753_RS04555	COG1253	flavin adenine dinucleotide binding
CW753_RS04560	COG2200	EAL domain
CW753_RS04565	COG1760	l-serine dehydratase
CW753_RS04585	COG0251	oxidation-reduction process
CW753_RS04590	COG1199	ATP-dependent helicase activity
CW753_RS04600	COG3065	identical protein binding
CW753_RS04610	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CW753_RS04620	COG2894	cell division
CW753_RS04635	COG0179	Fumarylacetoacetate (FAA) hydrolase
CW753_RS04665	COG2719	SpoVR family
CW753_RS04695	COG4774	siderophore transport
CW753_RS04710	COG2308	Evidence 4 Homologs of previously reported genes of
CW753_RS04750	COG0583	DNA-binding transcription factor activity
CW753_RS04755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CW753_RS04770	COG1882	Formate acetyltransferase
CW753_RS04800	COG0583	DNA-binding transcription factor activity
CW753_RS04835	COG0582	viral genome integration into host DNA
CW753_RS04885	COG3723	Recombinational DNA repair protein, rece pathway
CW753_RS05005	COG3772	lysozyme
CW753_RS05045	COG1783	phage Terminase large subunit
CW753_RS05120	COG3646	Phage regulatory protein
CW753_RS05215	COG3122	Protein conserved in bacteria
CW753_RS05240	COG2885	chlorophyll binding
CW753_RS05250	COG3039	Transposase
CW753_RS05290	COG0012	GTP binding
CW753_RS05310	COG0659	secondary active sulfate transmembrane transporter activity
CW753_RS05340	COG2890	protein-(glutamine-N5) methyltransferase activity
CW753_RS05360	COG0387	Pfam Sodium calcium exchanger
CW753_RS05365	COG4572	Cation transport regulator
CW753_RS05370	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CW753_RS05380	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CW753_RS05385	COG3707	response regulator
CW753_RS05390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CW753_RS05400	COG1116	anion transmembrane transporter activity
CW753_RS05405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CW753_RS05405	COG2146	nitrite reductase [NAD(P)H] activity
CW753_RS05410	COG0243	molybdopterin cofactor binding
CW753_RS05415	COG4932	domain protein
CW753_RS05420	COG2197	response regulator
CW753_RS05425	COG3850	Histidine kinase
CW753_RS05430	COG2223	nitrite transmembrane transporter activity
CW753_RS05435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CW753_RS05440	COG1140	nitrate reductase beta subunit
CW753_RS05445	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CW753_RS05450	COG2181	nitrate reductase activity
CW753_RS05460	COG1522	sequence-specific DNA binding
CW753_RS05490	COG0788	formyltetrahydrofolate deformylase activity
CW753_RS05500	COG1752	Esterase of the alpha-beta hydrolase superfamily
CW753_RS05505	COG0745	RESPONSE REGULATOR receiver
CW753_RS05510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CW753_RS05515	COG2916	Histone family protein nucleoid-structuring protein H-NS
CW753_RS05520	COG1435	thymidine kinase activity
CW753_RS05525	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS05525	COG1454	alcohol dehydrogenase
CW753_RS05535	COG2095	MarC family integral membrane protein
CW753_RS05540	COG4166	transmembrane transport
CW753_RS05550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CW753_RS05555	COG0444	Belongs to the ABC transporter superfamily
CW753_RS05565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CW753_RS05585	COG2353	YceI-like domain
CW753_RS05590	COG2350	Protein conserved in bacteria
CW753_RS05600	COG3001	Fructosamine kinase
CW753_RS05610	COG1105	Belongs to the carbohydrate kinase PfkB family
CW753_RS05615	COG3137	Salt-induced outer membrane protein
CW753_RS05660	COG0072	phenylalanine-tRNA ligase activity
CW753_RS05660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CW753_RS05680	COG0583	DNA-binding transcription factor activity
CW753_RS05700	COG0386	Belongs to the glutathione peroxidase family
CW753_RS05710	COG0791	NLP P60 protein
CW753_RS05720	COG4256	Hemin uptake protein
CW753_RS05725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CW753_RS05735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CW753_RS05735	COG0574	Belongs to the PEP-utilizing enzyme family
CW753_RS05745	COG0628	permease
CW753_RS05750	COG0277	FAD linked oxidase domain protein
CW753_RS05750	COG0247	lactate metabolic process
CW753_RS05755	COG2050	protein possibly involved in aromatic compounds catabolism
CW753_RS05760	COG2261	transglycosylase associated protein
CW753_RS05790	COG1120	ATPase activity
CW753_RS05795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CW753_RS05805	COG0583	DNA-binding transcription factor activity
CW753_RS05830	COG1304	FMN binding
CW753_RS05845	COG0316	Belongs to the HesB IscA family
CW753_RS05850	COG0719	Fe-S assembly protein
CW753_RS05855	COG0396	ATPase activity
CW753_RS05860	COG0719	Fe-S assembly protein
CW753_RS05875	COG1376	ErfK ybiS ycfS ynhG family protein
CW753_RS05900	COG1309	transcriptional regulator
CW753_RS05905	COG1082	Xylose isomerase domain protein TIM barrel
CW753_RS05905	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CW753_RS05910	COG2271	Major facilitator Superfamily
CW753_RS05915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CW753_RS05925	COG1120	ATPase activity
CW753_RS05930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CW753_RS05935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CW753_RS05940	COG1414	Transcriptional regulator
CW753_RS05975	COG2814	Major facilitator Superfamily
CW753_RS05995	COG0583	DNA-binding transcription factor activity
CW753_RS06000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CW753_RS06020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CW753_RS06025	COG1116	anion transmembrane transporter activity
CW753_RS06030	COG4774	siderophore transport
CW753_RS06035	COG1120	ATPase activity
CW753_RS06040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CW753_RS06045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CW753_RS06065	COG0765	amino acid transport
CW753_RS06070	COG1126	abc transporter atp-binding protein
CW753_RS06100	COG1473	amidohydrolase
CW753_RS06105	COG3383	formate dehydrogenase (NAD+) activity
CW753_RS06110	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CW753_RS06125	COG1175	transmembrane transport
CW753_RS06155	COG4133	protoheme IX ABC transporter activity
CW753_RS06160	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CW753_RS06165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CW753_RS06180	COG1138	Cytochrome C-type biogenesis protein
CW753_RS06185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CW753_RS06190	COG3088	subunit of a heme lyase
CW753_RS06190	COG4235	cytochrome complex assembly
CW753_RS06250	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS06260	COG1250	3-hydroxyacyl-CoA dehydrogenase
CW753_RS06270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CW753_RS06280	COG0583	DNA-binding transcription factor activity
CW753_RS06300	COG0277	FAD linked oxidase domain protein
CW753_RS06305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CW753_RS06330	COG0402	S-adenosylhomocysteine deaminase activity
CW753_RS06395	COG0444	Belongs to the ABC transporter superfamily
CW753_RS06420	COG0346	lactoylglutathione lyase activity
CW753_RS06425	COG1349	DNA-binding transcription factor activity
CW753_RS06455	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CW753_RS06475	COG0300	oxidoreductase activity
CW753_RS06515	COG0307	riboflavin synthase, alpha
CW753_RS06520	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CW753_RS06525	COG2814	Major facilitator Superfamily
CW753_RS06530	COG0583	DNA-binding transcription factor activity
CW753_RS06545	COG2814	Major facilitator Superfamily
CW753_RS06560	COG0791	NLP P60 protein
CW753_RS06565	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CW753_RS06575	COG0346	lactoylglutathione lyase activity
CW753_RS06580	COG1902	pentaerythritol trinitrate reductase activity
CW753_RS06585	COG1309	transcriptional regulator
CW753_RS06590	COG3313	Fe-S protein
CW753_RS06595	COG4989	oxidoreductase activity
CW753_RS06600	COG2032	superoxide dismutase activity
CW753_RS06605	COG1289	transmembrane transporter activity
CW753_RS06610	COG1566	PFAM secretion protein HlyD family protein
CW753_RS06640	COG3895	Periplasmic Protein
CW753_RS06655	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CW753_RS06660	COG0625	glutathione transferase activity
CW753_RS06675	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CW753_RS06685	COG4659	FMN binding
CW753_RS06720	COG2723	6-phospho-beta-galactosidase activity
CW753_RS06730	COG0673	inositol 2-dehydrogenase activity
CW753_RS06740	COG2814	Major facilitator Superfamily
CW753_RS06760	COG3038	cytochrome b561
CW753_RS06780	COG0583	DNA-binding transcription factor activity
CW753_RS06785	COG3485	protocatechuate 3,4-dioxygenase
CW753_RS06790	COG3485	protocatechuate 3,4-dioxygenase
CW753_RS06795	COG5383	Protein conserved in bacteria
CW753_RS06800	COG2272	Belongs to the type-B carboxylesterase lipase family
CW753_RS06815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CW753_RS06820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CW753_RS06825	COG1275	C4-dicarboxylate transporter malic acid transport protein
CW753_RS06830	COG0500	methyltransferase
CW753_RS06845	COG2207	Transcriptional regulator
CW753_RS06845	COG3708	Transcriptional regulator
CW753_RS06850	COG3135	benzoate transporter
CW753_RS06855	COG1396	sequence-specific DNA binding
CW753_RS06865	COG0826	peptidase U32
CW753_RS06885	COG1294	oxidase, subunit
CW753_RS06890	COG1271	oxidase subunit
CW753_RS06895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CW753_RS06900	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CW753_RS06905	COG3842	ATPase activity
CW753_RS06910	COG1176	ABC-type spermidine putrescine transport system, permease component I
CW753_RS06915	COG1177	transmembrane transport
CW753_RS06920	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS06930	COG3039	Transposase
CW753_RS06960	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS06965	COG0747	negative chemotaxis
CW753_RS06975	COG3238	Protein conserved in bacteria
CW753_RS06980	COG1247	-acetyltransferase
CW753_RS06990	COG2130	NADP-dependent
CW753_RS07005	COG3691	Protein conserved in bacteria
CW753_RS07015	COG4772	TonB-dependent receptor
CW753_RS07040	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CW753_RS07045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CW753_RS07050	COG1473	amidohydrolase
CW753_RS07060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CW753_RS07065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CW753_RS07075	COG0765	amino acid transport
CW753_RS07080	COG1126	abc transporter atp-binding protein
CW753_RS07090	COG0625	glutathione transferase activity
CW753_RS07125	COG2211	Major facilitator Superfamily
CW753_RS07140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CW753_RS07145	COG3842	ATPase activity
CW753_RS07150	COG1840	ABC-type Fe3 transport system, periplasmic component
CW753_RS07155	COG1178	ABC-type Fe3 transport system permease component
CW753_RS07160	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CW753_RS07165	COG2181	nitrate reductase activity
CW753_RS07170	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CW753_RS07175	COG1140	nitrate reductase beta subunit
CW753_RS07180	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CW753_RS07200	COG1414	Transcriptional regulator
CW753_RS07205	COG4948	Mandelate Racemase Muconate Lactonizing
CW753_RS07210	COG4829	muconolactone delta-isomerase
CW753_RS07215	COG3485	protocatechuate 3,4-dioxygenase
CW753_RS07225	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CW753_RS07245	COG0243	molybdopterin cofactor binding
CW753_RS07245	COG3383	formate dehydrogenase (NAD+) activity
CW753_RS07250	COG3383	formate dehydrogenase (NAD+) activity
CW753_RS07250	COG0243	molybdopterin cofactor binding
CW753_RS07255	COG0437	4 iron, 4 sulfur cluster binding
CW753_RS07260	COG2864	formate dehydrogenase
CW753_RS07285	COG2814	Major facilitator Superfamily
CW753_RS07295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CW753_RS07305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CW753_RS07320	COG1064	alcohol dehydrogenase
CW753_RS07335	COG0488	(ABC) transporter
CW753_RS07380	COG3685	Protein conserved in bacteria
CW753_RS07390	COG0366	Alpha amylase catalytic
CW753_RS07400	COG2323	membrane
CW753_RS07410	COG3111	PFAM Bacterial OB fold (BOF) protein
CW753_RS07415	COG1764	response to oxidative stress
CW753_RS07440	COG3781	membrane
CW753_RS07445	COG0243	molybdopterin cofactor binding
CW753_RS07450	COG0583	DNA-binding transcription factor activity
CW753_RS07455	COG1447	Phosphotransferase system cellobiose-specific component IIA
CW753_RS07460	COG2814	Major facilitator Superfamily
CW753_RS07470	COG1285	pathogenesis
CW753_RS07475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CW753_RS07485	COG0583	DNA-binding transcription factor activity
CW753_RS07505	COG0519	Catalyzes the synthesis of GMP from XMP
CW753_RS07505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CW753_RS07545	COG0596	Alpha beta hydrolase
CW753_RS07555	COG2205	protein histidine kinase activity
CW753_RS07570	COG0076	glutamate decarboxylase activity
CW753_RS07575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CW753_RS07580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CW753_RS07585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CW753_RS07590	COG1116	anion transmembrane transporter activity
CW753_RS07595	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CW753_RS07610	COG0673	inositol 2-dehydrogenase activity
CW753_RS07620	COG1609	Transcriptional regulator
CW753_RS07625	COG3706	GGDEF domain
CW753_RS07630	COG0402	S-adenosylhomocysteine deaminase activity
CW753_RS07635	COG1953	Uracil, thiamine, allantoin
CW753_RS07685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CW753_RS07700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CW753_RS07745	COG0765	amino acid transport
CW753_RS07755	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CW753_RS07765	COG2070	2-Nitropropane dioxygenase
CW753_RS07770	COG0583	DNA-binding transcription factor activity
CW753_RS07780	COG1902	pentaerythritol trinitrate reductase activity
CW753_RS07785	COG4529	Protein conserved in bacteria
CW753_RS07790	COG0477	Major facilitator Superfamily
CW753_RS07820	COG2223	nitrite transmembrane transporter activity
CW753_RS07830	COG1609	Transcriptional regulator
CW753_RS07835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CW753_RS07845	COG3037	sugar-specific permease SgaT UlaA
CW753_RS07850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CW753_RS07860	COG3039	Transposase
CW753_RS07875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CW753_RS07900	COG4372	Transposase
CW753_RS07905	COG3436	PFAM IS66 Orf2 family protein
CW753_RS07920	COG2801	Transposase and inactivated derivatives
CW753_RS07935	COG3039	Transposase
CW753_RS07945	COG1349	DNA-binding transcription factor activity
CW753_RS07960	COG1349	DNA-binding transcription factor activity
CW753_RS07965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CW753_RS07970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CW753_RS07975	COG0738	Major facilitator superfamily
CW753_RS08020	COG1929	Belongs to the glycerate kinase type-1 family
CW753_RS08025	COG3835	regulator
CW753_RS08035	COG0583	DNA-binding transcription factor activity
CW753_RS08045	COG2186	Transcriptional regulator
CW753_RS08050	COG1263	PTS System
CW753_RS08050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CW753_RS08060	COG2814	Major facilitator Superfamily
CW753_RS08065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CW753_RS08065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CW753_RS08075	COG2819	hydrolase of the alpha beta superfamily
CW753_RS08125	COG3188	usher protein
CW753_RS08135	COG1649	PFAM Uncharacterised BCR, COG1649
CW753_RS08140	COG3550	peptidyl-serine autophosphorylation
CW753_RS08145	COG1396	sequence-specific DNA binding
CW753_RS08150	COG2351	hydroxyisourate hydrolase activity
CW753_RS08155	COG3195	allantoin biosynthetic process
CW753_RS08155	COG3648	Uricase
CW753_RS08190	COG2207	Transcriptional regulator
CW753_RS08205	COG4628	conserved protein (DUF2132)
CW753_RS08225	COG2011	ABC-type metal ion transport system permease component
CW753_RS08230	COG2070	2-Nitropropane dioxygenase
CW753_RS08240	COG0477	Major facilitator Superfamily
CW753_RS08300	COG2199	diguanylate cyclase activity
CW753_RS08315	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS08320	COG0583	DNA-binding transcription factor activity
CW753_RS08330	COG0039	L-malate dehydrogenase activity
CW753_RS08335	COG1349	DNA-binding transcription factor activity
CW753_RS08340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CW753_RS08345	COG3395	kinase activity
CW753_RS08355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CW753_RS08360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CW753_RS08365	COG2271	Major facilitator Superfamily
CW753_RS08390	COG4977	sequence-specific DNA binding
CW753_RS08400	COG0697	spore germination
CW753_RS08405	COG2814	Major facilitator Superfamily
CW753_RS08420	COG1129	ABC transporter
CW753_RS08435	COG0683	leucine binding
CW753_RS08440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CW753_RS08475	COG2223	nitrite transmembrane transporter activity
CW753_RS08495	COG1349	DNA-binding transcription factor activity
CW753_RS08505	COG2084	Dehydrogenase
CW753_RS08515	COG0235	Class ii aldolase
CW753_RS08520	COG3622	Belongs to the hyi family
CW753_RS08525	COG2610	gluconate transmembrane transporter activity
CW753_RS08560	COG1546	Belongs to the CinA family
CW753_RS08565	COG0071	Belongs to the small heat shock protein (HSP20) family
CW753_RS08580	COG2197	response regulator
CW753_RS08585	COG2135	peptidase activity
CW753_RS08590	COG2207	Transcriptional regulator
CW753_RS08605	COG4221	oxidoreductase activity
CW753_RS08610	COG1802	Transcriptional regulator
CW753_RS08615	COG0589	response to stress
CW753_RS08620	COG0246	Mannitol dehydrogenase
CW753_RS08625	COG2271	Major facilitator Superfamily
CW753_RS08640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CW753_RS08670	COG0437	4 iron, 4 sulfur cluster binding
CW753_RS08675	COG3302	dmso reductase anchor subunit
CW753_RS08690	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CW753_RS08695	COG1940	carbohydrate kinase activity
CW753_RS08700	COG0583	DNA-binding transcription factor activity
CW753_RS08705	COG2814	Major facilitator Superfamily
CW753_RS08710	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CW753_RS08720	COG3591	Belongs to the peptidase S1B family
CW753_RS08740	COG0628	permease
CW753_RS08770	COG0679	Auxin Efflux Carrier
CW753_RS08780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CW753_RS08805	COG3290	protein histidine kinase activity
CW753_RS08810	COG4565	transcriptional regulatory protein
CW753_RS08835	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CW753_RS08835	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CW753_RS08855	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CW753_RS08860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CW753_RS08870	COG0183	Belongs to the thiolase family
CW753_RS08875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CW753_RS08885	COG1414	Transcriptional regulator
CW753_RS08890	COG2840	Smr protein MutS2
CW753_RS08895	COG0583	DNA-binding transcription factor activity
CW753_RS08905	COG1473	amidohydrolase
CW753_RS09075	COG3772	lysozyme
CW753_RS09095	COG1403	HNH endonuclease
CW753_RS09100	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CW753_RS09110	COG1846	Transcriptional regulator
CW753_RS09135	COG1396	sequence-specific DNA binding
CW753_RS09190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CW753_RS09205	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CW753_RS09210	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CW753_RS09230	COG0531	amino acid
CW753_RS09240	COG3136	membrane protein required for alginate biosynthesis
CW753_RS09245	COG0745	RESPONSE REGULATOR receiver
CW753_RS09255	COG2205	protein histidine kinase activity
CW753_RS09265	COG0114	fumarate hydratase activity
CW753_RS09270	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CW753_RS09270	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CW753_RS09275	COG1482	cell wall glycoprotein biosynthetic process
CW753_RS09280	COG5339	Protein conserved in bacteria
CW753_RS09285	COG1609	Transcriptional regulator
CW753_RS09290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CW753_RS09290	COG1263	PTS System
CW753_RS09295	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CW753_RS09320	COG2391	methyltransferase activity
CW753_RS09325	COG0425	Belongs to the sulfur carrier protein TusA family
CW753_RS09330	COG5562	phage envelope protein
CW753_RS09335	COG0401	homolog of Blt101
CW753_RS09350	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS09355	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CW753_RS09360	COG0477	Major facilitator Superfamily
CW753_RS09365	COG1113	amino acid transport
CW753_RS09370	COG2988	succinylglutamate desuccinylase activity
CW753_RS09375	COG3724	N-succinylarginine dihydrolase activity
CW753_RS09380	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS09385	COG3138	arginine N-succinyltransferase
CW753_RS09390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CW753_RS09395	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CW753_RS09400	COG0667	Aldo Keto reductase
CW753_RS09405	COG0583	DNA-binding transcription factor activity
CW753_RS09430	COG4122	O-methyltransferase activity
CW753_RS09435	COG1643	Atp-dependent helicase
CW753_RS09450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CW753_RS09455	COG3327	negative regulation of DNA-templated transcription, initiation
CW753_RS09460	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CW753_RS09465	COG0183	Belongs to the thiolase family
CW753_RS09470	COG2050	protein possibly involved in aromatic compounds catabolism
CW753_RS09475	COG1250	3-hydroxyacyl-CoA dehydrogenase
CW753_RS09480	COG1024	Enoyl-CoA hydratase
CW753_RS09485	COG1024	Enoyl-CoA hydratase
CW753_RS09490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CW753_RS09495	COG2151	metal-sulfur cluster biosynthetic enzyme
CW753_RS09500	COG3396	Phenylacetate-CoA oxygenase
CW753_RS09505	COG3460	Phenylacetate-CoA oxygenase
CW753_RS09510	COG3396	Phenylacetate-CoA oxygenase
CW753_RS09550	COG2072	flavoprotein involved in K transport
CW753_RS09555	COG0583	DNA-binding transcription factor activity
CW753_RS09560	COG1126	abc transporter atp-binding protein
CW753_RS09570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CW753_RS09620	COG2207	Transcriptional regulator
CW753_RS09625	COG3784	Protein of unknown function (DUF1318)
CW753_RS09635	COG2911	Protein conserved in bacteria
CW753_RS09640	COG0586	Pfam SNARE associated Golgi protein
CW753_RS09645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CW753_RS09650	COG3187	Heat shock protein
CW753_RS09655	COG3042	response to heat
CW753_RS09665	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CW753_RS09665	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CW753_RS09665	COG1013	pyruvate-flavodoxin oxidoreductase activity
CW753_RS09665	COG0674	pyruvate-flavodoxin oxidoreductase activity
CW753_RS09670	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CW753_RS09680	COG0589	response to stress
CW753_RS09690	COG0513	Belongs to the DEAD box helicase family
CW753_RS09705	COG1349	DNA-binding transcription factor activity
CW753_RS09710	COG0673	inositol 2-dehydrogenase activity
CW753_RS09725	COG1113	amino acid transport
CW753_RS09730	COG1522	sequence-specific DNA binding
CW753_RS09740	COG1448	Aminotransferase
CW753_RS09745	COG2011	ABC-type metal ion transport system permease component
CW753_RS09775	COG4166	transmembrane transport
CW753_RS09780	COG2866	Carboxypeptidase
CW753_RS09785	COG4948	Mandelate Racemase Muconate Lactonizing
CW753_RS09790	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CW753_RS09795	COG3180	Ammonia monooxygenase
CW753_RS09805	COG1486	melibiose metabolic process
CW753_RS09810	COG0583	DNA-binding transcription factor activity
CW753_RS09820	COG3106	COG3106 Predicted ATPase
CW753_RS09830	COG1983	PspC domain protein
CW753_RS09840	COG1842	Phage shock protein A
CW753_RS09845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CW753_RS09855	COG1473	amidohydrolase
CW753_RS09870	COG0702	epimerase
CW753_RS09885	COG4171	peptide transport system, permease
CW753_RS09900	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CW753_RS09910	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CW753_RS09915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CW753_RS09915	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CW753_RS09930	COG1349	DNA-binding transcription factor activity
CW753_RS09940	COG0023	Translation Initiation Factor
CW753_RS09950	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CW753_RS09955	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CW753_RS09960	COG0671	phosphoesterase, PA-phosphatase related
CW753_RS09970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CW753_RS10000	COG0616	signal peptide processing
CW753_RS10010	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS10015	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CW753_RS10025	COG0583	DNA-binding transcription factor activity
CW753_RS10035	COG0009	L-threonylcarbamoyladenylate synthase
CW753_RS10045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CW753_RS10050	COG0512	Glutamine amidotransferase of anthranilate synthase
CW753_RS10050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CW753_RS10055	COG0134	indole-3-glycerol-phosphate synthase activity
CW753_RS10055	COG0135	phosphoribosylanthranilate isomerase activity
CW753_RS10090	COG4774	siderophore transport
CW753_RS10100	COG3047	cAMP biosynthetic process
CW753_RS10105	COG0727	PFAM Uncharacterised protein family (UPF0153)
CW753_RS10135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CW753_RS10140	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS10145	COG1988	membrane-bound metal-dependent
CW753_RS10150	COG1823	symporter activity
CW753_RS10160	COG0753	catalase activity
CW753_RS10170	COG1486	melibiose metabolic process
CW753_RS10175	COG3039	Transposase
CW753_RS10185	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CW753_RS10195	COG0322	excinuclease ABC activity
CW753_RS10200	COG3678	ATP-independent chaperone mediated protein folding
CW753_RS10210	COG3724	N-succinylarginine dihydrolase activity
CW753_RS10220	COG3138	arginine N-succinyltransferase
CW753_RS10230	COG0708	Exodeoxyribonuclease III
CW753_RS10235	COG0398	Pfam SNARE associated Golgi protein
CW753_RS10240	COG0398	Pfam SNARE associated Golgi protein
CW753_RS10245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CW753_RS10250	COG4134	Bacterial extracellular solute-binding protein
CW753_RS10255	COG4135	transport system, permease component
CW753_RS10265	COG2897	thiosulfate sulfurtransferase activity
CW753_RS10270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CW753_RS10275	COG0494	nUDIX hydrolase
CW753_RS10280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CW753_RS10285	COG0604	alcohol dehydrogenase
CW753_RS10285	COG3321	synthase
CW753_RS10285	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS10290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CW753_RS10295	COG0709	Synthesizes selenophosphate from selenide and ATP
CW753_RS10310	COG0778	Nitroreductase
CW753_RS10315	COG0616	signal peptide processing
CW753_RS10320	COG0252	asparaginase activity
CW753_RS10325	COG1335	isochorismatase
CW753_RS10340	COG3139	Protein of unknown function (DUF1315)
CW753_RS10360	COG0656	L-ascorbic acid biosynthetic process
CW753_RS10365	COG3713	MltA-interacting MipA family protein
CW753_RS10370	COG2766	serine protein kinase
CW753_RS10385	COG0386	Belongs to the glutathione peroxidase family
CW753_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS10410	COG0583	DNA-binding transcription factor activity
CW753_RS10415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CW753_RS10420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CW753_RS10440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CW753_RS10450	COG2207	Transcriptional regulator
CW753_RS10455	COG2807	transmembrane transport
CW753_RS10460	COG0504	CTP synthase activity
CW753_RS10465	COG1683	Conserved Protein
CW753_RS10470	COG3189	MarR family transcriptional regulator
CW753_RS10475	COG3042	response to heat
CW753_RS10480	COG2199	diguanylate cyclase activity
CW753_RS10480	COG2203	Gaf domain
CW753_RS10500	COG3182	Iron-regulated membrane protein
CW753_RS10510	COG1560	Kdo2-lipid A biosynthetic process
CW753_RS10525	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CW753_RS10530	COG3706	GGDEF domain
CW753_RS10535	COG0583	DNA-binding transcription factor activity
CW753_RS10540	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CW753_RS10580	COG1294	oxidase, subunit
CW753_RS10590	COG3546	catalase activity
CW753_RS10595	COG3685	Protein conserved in bacteria
CW753_RS10600	COG3685	Protein conserved in bacteria
CW753_RS10605	COG3729	General stress protein
CW753_RS10615	COG3813	Protein conserved in bacteria
CW753_RS10635	COG0640	Transcriptional regulator
CW753_RS10640	COG0538	isocitrate dehydrogenase activity
CW753_RS10730	COG0616	signal peptide processing
CW753_RS10745	COG4626	Terminase
CW753_RS10745	COG1802	Transcriptional regulator
CW753_RS10790	COG3772	lysozyme
CW753_RS10800	COG1598	PFAM Uncharacterised protein family UPF0150
CW753_RS10805	COG1724	mRNA binding
CW753_RS10815	COG3039	Transposase
CW753_RS10835	COG1403	HNH endonuclease
CW753_RS10945	COG0582	viral genome integration into host DNA
CW753_RS10950	COG0538	isocitrate dehydrogenase activity
CW753_RS10955	COG1187	pseudouridine synthase activity
CW753_RS10975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CW753_RS10995	COG2205	protein histidine kinase activity
CW753_RS11000	COG2850	peptidyl-arginine hydroxylation
CW753_RS11020	COG1177	transmembrane transport
CW753_RS11035	COG0318	PFAM AMP-dependent synthetase and ligase
CW753_RS11040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CW753_RS11045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CW753_RS11050	COG0698	ribose 5-phosphate isomerase
CW753_RS11065	COG3395	kinase activity
CW753_RS11080	COG2390	Transcriptional regulator
CW753_RS11090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CW753_RS11100	COG4591	ABC-type transport system involved in lipoprotein release permease component
CW753_RS11110	COG4591	ABC-type transport system involved in lipoprotein release permease component
CW753_RS11115	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CW753_RS11120	COG1388	LysM domain
CW753_RS11120	COG1376	ErfK ybiS ycfS ynhG family protein
CW753_RS11130	COG1309	transcriptional regulator
CW753_RS11140	COG3134	Outer membrane lipoprotein
CW753_RS11145	COG1252	NADH dehydrogenase
CW753_RS11170	COG5633	Lipoprotein
CW753_RS11175	COG0537	adenosine 5'-monophosphoramidase activity
CW753_RS11180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CW753_RS11180	COG1263	PTS System
CW753_RS11185	COG0084	hydrolase, TatD family'
CW753_RS11190	COG0470	DNA polymerase III
CW753_RS11200	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CW753_RS11205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CW753_RS11210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CW753_RS11225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CW753_RS11245	COG1399	metal-binding, possibly nucleic acid-binding protein
CW753_RS11265	COG1530	ribonuclease E activity
CW753_RS11270	COG0583	DNA-binding transcription factor activity
CW753_RS11275	COG2814	Major facilitator Superfamily
CW753_RS11295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CW753_RS11345	COG1560	Kdo2-lipid A biosynthetic process
CW753_RS11365	COG5645	(Lipo)protein
CW753_RS11405	COG3381	protein complex oligomerization
CW753_RS11435	COG0583	DNA-binding transcription factor activity
CW753_RS11445	COG1335	isochorismatase
CW753_RS11460	COG1702	phosphate starvation-inducible protein PhoH
CW753_RS11480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CW753_RS11505	COG1309	transcriptional regulator
CW753_RS11540	COG2233	PERMEase
CW753_RS11555	COG3729	General stress protein
CW753_RS11580	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS11595	COG0531	amino acid
CW753_RS11605	COG0174	glutamine synthetase
CW753_RS11610	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CW753_RS11615	COG1396	sequence-specific DNA binding
CW753_RS11615	COG1917	Cupin 2, conserved barrel domain protein
CW753_RS11620	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS11625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CW753_RS11630	COG0583	DNA-binding transcription factor activity
CW753_RS11635	COG0473	3-isopropylmalate dehydrogenase activity
CW753_RS11640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CW753_RS11645	COG4638	Rieske (2fe-2S)
CW753_RS11650	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS11655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CW753_RS11665	COG2200	EAL domain
CW753_RS11670	COG2200	EAL domain
CW753_RS11685	COG0670	Belongs to the BI1 family
CW753_RS11700	COG2207	Transcriptional regulator
CW753_RS11705	COG1881	PFAM PEBP family protein
CW753_RS11720	COG1832	CoA-binding protein
CW753_RS11730	COG0210	DNA helicase
CW753_RS11735	COG3304	Inner membrane component domain
CW753_RS11740	COG1289	transmembrane transporter activity
CW753_RS11745	COG3070	regulator of competence-specific genes
CW753_RS11770	COG1067	ATP-dependent peptidase activity
CW753_RS11780	COG3130	regulation of translation
CW753_RS11785	COG3009	Protein conserved in bacteria
CW753_RS11790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CW753_RS11790	COG3008	intermembrane lipid transfer
CW753_RS11795	COG2995	paraquat-inducible protein a
CW753_RS11800	COG0488	(ABC) transporter
CW753_RS11810	COG3217	Mosc domain protein beta barrel domain protein
CW753_RS11810	COG0633	Ferredoxin
CW753_RS11825	COG0431	NADPH-dependent FMN reductase
CW753_RS11830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CW753_RS11835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CW753_RS11840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CW753_RS11850	COG0308	aminopeptidase N
CW753_RS11860	COG1473	amidohydrolase
CW753_RS11870	COG0814	amino acid
CW753_RS11880	COG1522	sequence-specific DNA binding
CW753_RS11890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CW753_RS11895	COG1448	Aminotransferase
CW753_RS11900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CW753_RS11905	COG3108	Peptidase M15
CW753_RS11910	COG2989	Protein conserved in bacteria
CW753_RS11920	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CW753_RS11930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CW753_RS11935	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CW753_RS11940	COG3173	Aminoglycoside phosphotransferase
CW753_RS11955	COG3214	Protein conserved in bacteria
CW753_RS11970	COG0658	competence protein
CW753_RS11970	COG2333	competence protein COMEC
CW753_RS11980	COG0539	negative regulation of cytoplasmic translation
CW753_RS12000	COG2323	membrane
CW753_RS12005	COG1944	ATP diphosphatase activity
CW753_RS12010	COG2116	formate transmembrane transporter activity
CW753_RS12020	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CW753_RS12025	COG0477	Major facilitator Superfamily
CW753_RS12035	COG3302	dmso reductase anchor subunit
CW753_RS12040	COG0437	4 iron, 4 sulfur cluster binding
CW753_RS12045	COG0243	molybdopterin cofactor binding
CW753_RS12055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CW753_RS12065	COG1178	ABC-type Fe3 transport system permease component
CW753_RS12065	COG1674	ftsk spoiiie
CW753_RS12075	COG0492	ferredoxin-NADP+ reductase activity
CW753_RS12080	COG4988	ABC transporter
CW753_RS12085	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CW753_RS12100	COG0542	response to heat
CW753_RS12110	COG1278	Cold shock
CW753_RS12120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CW753_RS12125	COG3593	DNA synthesis involved in DNA repair
CW753_RS12135	COG2431	L-lysine efflux transmembrane transporter activity
CW753_RS12145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CW753_RS12160	COG0028	Belongs to the TPP enzyme family
CW753_RS12165	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CW753_RS12170	COG0702	epimerase
CW753_RS12175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CW753_RS12180	COG3023	N-Acetylmuramoyl-L-alanine amidase
CW753_RS12185	COG4251	negative regulation of phosphorylation
CW753_RS12185	COG3706	GGDEF domain
CW753_RS12185	COG5001	Diguanylate cyclase
CW753_RS12185	COG2203	Gaf domain
CW753_RS12200	COG3039	Transposase
CW753_RS12210	COG1126	abc transporter atp-binding protein
CW753_RS12215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CW753_RS12220	COG4215	(ABC) transporter
CW753_RS12225	COG4160	amino acid transport
CW753_RS12230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CW753_RS12235	COG5002	protein histidine kinase activity
CW753_RS12240	COG0745	RESPONSE REGULATOR receiver
CW753_RS12255	COG1177	transmembrane transport
CW753_RS12260	COG1176	ABC-type spermidine putrescine transport system, permease component I
CW753_RS12265	COG3842	ATPase activity
CW753_RS12270	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CW753_RS12285	COG0778	Nitroreductase
CW753_RS12310	COG3226	Transcriptional regulator
CW753_RS12315	COG0738	Major facilitator superfamily
CW753_RS12320	COG0561	phosphatase activity
CW753_RS12325	COG2814	Major facilitator Superfamily
CW753_RS12335	COG0671	phosphoesterase, PA-phosphatase related
CW753_RS12340	COG1349	DNA-binding transcription factor activity
CW753_RS12345	COG1686	Belongs to the peptidase S11 family
CW753_RS12350	COG0625	glutathione transferase activity
CW753_RS12355	COG2133	pyrroloquinoline quinone binding
CW753_RS12365	COG3039	Transposase
CW753_RS12375	COG2223	nitrite transmembrane transporter activity
CW753_RS12400	COG0747	negative chemotaxis
CW753_RS12415	COG0303	'Molybdopterin
CW753_RS12420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CW753_RS12425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CW753_RS12430	COG1882	Formate acetyltransferase
CW753_RS12435	COG0561	phosphatase activity
CW753_RS12445	COG1609	Transcriptional regulator
CW753_RS12450	COG2271	Major facilitator Superfamily
CW753_RS12460	COG0488	(ABC) transporter
CW753_RS12465	COG2365	Tyrosine phosphatase family
CW753_RS12475	COG2188	Transcriptional regulator
CW753_RS12480	COG2723	6-phospho-beta-galactosidase activity
CW753_RS12485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CW753_RS12500	COG2194	sulfuric ester hydrolase activity
CW753_RS12505	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CW753_RS12520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CW753_RS12525	COG0765	amino acid transport
CW753_RS12530	COG1126	abc transporter atp-binding protein
CW753_RS12535	COG0668	transmembrane transport
CW753_RS12545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CW753_RS12555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CW753_RS12565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CW753_RS12570	COG1199	ATP-dependent helicase activity
CW753_RS12575	COG0513	Belongs to the DEAD box helicase family
CW753_RS12580	COG3958	Transketolase
CW753_RS12585	COG3959	Transketolase, thiamine diphosphate binding domain
CW753_RS12590	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS12595	COG2271	Major facilitator Superfamily
CW753_RS12615	COG1309	transcriptional regulator
CW753_RS12620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CW753_RS12625	COG1131	(ABC) transporter
CW753_RS12630	COG0842	Transport permease protein
CW753_RS12635	COG0842	Transport permease protein
CW753_RS12645	COG3568	Endonuclease Exonuclease Phosphatase
CW753_RS12650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CW753_RS12655	COG0392	lysyltransferase activity
CW753_RS12660	COG0670	Belongs to the BI1 family
CW753_RS12665	COG0314	molybdopterin synthase activity
CW753_RS12670	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CW753_RS12680	COG0521	Mo-molybdopterin cofactor biosynthetic process
CW753_RS12705	COG0745	RESPONSE REGULATOR receiver
CW753_RS12710	COG0642	Histidine kinase
CW753_RS12750	COG2226	methyltransferase
CW753_RS12765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CW753_RS12770	COG1881	PFAM PEBP family protein
CW753_RS12810	COG4677	pectinesterase activity
CW753_RS12820	COG0589	response to stress
CW753_RS12825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CW753_RS12855	COG0789	Transcriptional regulator
CW753_RS12860	COG2200	EAL domain
CW753_RS12885	COG0561	phosphatase activity
CW753_RS12900	COG0725	ABC transporter, periplasmic molybdate-binding protein
CW753_RS12910	COG3585	molybdate ion transport
CW753_RS12910	COG2005	Transcriptional regulator
CW753_RS12915	COG1119	ATPase activity
CW753_RS12925	COG1085	galactose-1-phosphate uridylyltransferase
CW753_RS12935	COG2017	converts alpha-aldose to the beta-anomer
CW753_RS12945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CW753_RS12960	COG3201	nicotinamide mononucleotide transporter
CW753_RS12965	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CW753_RS13010	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CW753_RS13015	COG2885	chlorophyll binding
CW753_RS13025	COG3064	Membrane
CW753_RS13030	COG0848	biopolymer transport protein
CW753_RS13035	COG0811	peptide transport
CW753_RS13040	COG0824	Thioesterase
CW753_RS13045	COG3790	cyd operon protein YbgE
CW753_RS13050	COG4890	Cyd operon protein YbgT
CW753_RS13055	COG1294	oxidase, subunit
CW753_RS13060	COG1271	oxidase subunit
CW753_RS13065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CW753_RS13080	COG0508	dehydrogenase complex catalyzes the overall conversion of
CW753_RS13085	COG0567	Dehydrogenase, E1 component
CW753_RS13090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CW753_RS13095	COG1053	succinate dehydrogenase
CW753_RS13100	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CW753_RS13105	COG2009	succinate dehydrogenase
CW753_RS13140	COG1984	allophanate hydrolase subunit 2
CW753_RS13145	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CW753_RS13160	COG0415	Belongs to the DNA photolyase family
CW753_RS13190	COG2205	protein histidine kinase activity
CW753_RS13195	COG0745	RESPONSE REGULATOR receiver
CW753_RS13205	COG0033	Phosphoglucomutase
CW753_RS13215	COG0596	Alpha beta hydrolase
CW753_RS13230	COG0735	belongs to the Fur family
CW753_RS13270	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CW753_RS13275	COG1846	Transcriptional regulator
CW753_RS13275	COG1940	carbohydrate kinase activity
CW753_RS13280	COG0647	UMP catabolic process
CW753_RS13285	COG0367	asparagine synthase
CW753_RS13330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CW753_RS13340	COG1702	phosphate starvation-inducible protein PhoH
CW753_RS13365	COG0765	amino acid transport
CW753_RS13370	COG0765	amino acid transport
CW753_RS13375	COG1126	abc transporter atp-binding protein
CW753_RS13400	COG2888	peptidyl-tyrosine sulfation
CW753_RS13415	COG1466	dna polymerase III delta subunit
CW753_RS13430	COG0799	negative regulation of ribosome biogenesis
CW753_RS13440	COG0768	penicillin binding
CW753_RS13445	COG0772	Belongs to the SEDS family
CW753_RS13450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CW753_RS13455	COG1686	Belongs to the peptidase S11 family
CW753_RS13470	COG0583	DNA-binding transcription factor activity
CW753_RS13485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CW753_RS13510	COG3069	C4-dicarboxylate transmembrane transporter activity
CW753_RS13515	COG3719	Belongs to the RNase T2 family
CW753_RS13520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CW753_RS13540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CW753_RS13545	COG0583	DNA-binding transcription factor activity
CW753_RS13550	COG3969	phosphoadenosine phosphosulfate
CW753_RS13555	COG1475	DNA binding
CW753_RS13560	COG0436	Aminotransferase
CW753_RS13585	COG1129	ABC transporter
CW753_RS13590	COG1172	Belongs to the binding-protein-dependent transport system permease family
CW753_RS13595	COG1172	Belongs to the binding-protein-dependent transport system permease family
CW753_RS13605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CW753_RS13630	COG0402	S-adenosylhomocysteine deaminase activity
CW753_RS13640	COG0483	inositol monophosphate 1-phosphatase activity
CW753_RS13645	COG2271	Major facilitator Superfamily
CW753_RS13675	COG1172	Belongs to the binding-protein-dependent transport system permease family
CW753_RS13680	COG1129	ABC transporter
CW753_RS13685	COG0371	Dehydrogenase
CW753_RS13690	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS13705	COG2879	small protein
CW753_RS13710	COG1966	Carbon starvation protein
CW753_RS13720	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS13725	COG3433	isochorismatase activity
CW753_RS13725	COG1535	isochorismatase
CW753_RS13730	COG1021	2,3-dihydroxybenzoate-AMP ligase
CW753_RS13735	COG1169	isochorismate synthase
CW753_RS13740	COG4592	Periplasmic binding protein
CW753_RS13750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CW753_RS13755	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CW753_RS13760	COG1120	ATPase activity
CW753_RS13770	COG3251	PFAM MbtH domain protein
CW753_RS13785	COG4771	TonB-dependent receptor
CW753_RS13790	COG2977	Belongs to the P-Pant transferase superfamily
CW753_RS13795	COG3958	Transketolase
CW753_RS13800	COG3959	Transketolase, thiamine diphosphate binding domain
CW753_RS13810	COG2390	Transcriptional regulator
CW753_RS13815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CW753_RS13820	COG1879	ABC-type sugar transport system periplasmic component
CW753_RS13830	COG1129	ABC transporter
CW753_RS13835	COG1172	Belongs to the binding-protein-dependent transport system permease family
CW753_RS13845	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS13855	COG0583	DNA-binding transcription factor activity
CW753_RS13860	COG0668	transmembrane transport
CW753_RS13895	COG0747	negative chemotaxis
CW753_RS13900	COG0601	transmembrane transport
CW753_RS13905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CW753_RS13910	COG0444	Belongs to the ABC transporter superfamily
CW753_RS13915	COG4608	Belongs to the ABC transporter superfamily
CW753_RS13930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CW753_RS13935	COG4221	oxidoreductase activity
CW753_RS13945	COG4215	(ABC) transporter
CW753_RS13950	COG0765	amino acid transport
CW753_RS13955	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CW753_RS13970	COG0697	spore germination
CW753_RS13985	COG4608	Belongs to the ABC transporter superfamily
CW753_RS13990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CW753_RS14000	COG4166	transmembrane transport
CW753_RS14010	COG3698	Phosphodiester glycosidase
CW753_RS14065	COG2315	Protein conserved in bacteria
CW753_RS14070	COG0778	Nitroreductase
CW753_RS14100	COG0477	Major facilitator Superfamily
CW753_RS14105	COG0668	transmembrane transport
CW753_RS14120	COG0673	inositol 2-dehydrogenase activity
CW753_RS14130	COG2211	Major facilitator Superfamily
CW753_RS14135	COG1113	amino acid transport
CW753_RS14150	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS14155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CW753_RS14165	COG0531	amino acid
CW753_RS14210	COG0667	Aldo Keto reductase
CW753_RS14215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CW753_RS14220	COG1473	amidohydrolase
CW753_RS14240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CW753_RS14245	COG1120	ATPase activity
CW753_RS14250	COG1566	PFAM secretion protein HlyD family protein
CW753_RS14295	COG4211	Belongs to the binding-protein-dependent transport system permease family
CW753_RS14315	COG0673	inositol 2-dehydrogenase activity
CW753_RS14345	COG3104	oligopeptide transport
CW753_RS14350	COG1982	Orn Lys Arg decarboxylase major
CW753_RS14355	COG0531	amino acid
CW753_RS14360	COG3710	Transcriptional regulator
CW753_RS14375	COG1560	Kdo2-lipid A biosynthetic process
CW753_RS14390	COG3188	usher protein
CW753_RS14395	COG3121	Chaperone
CW753_RS14400	COG3539	Fimbrial protein
CW753_RS14590	COG3567	Phage-associated protein, HI1409 family
CW753_RS14595	COG1783	phage Terminase large subunit
CW753_RS14605	COG3772	lysozyme
CW753_RS14640	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CW753_RS14785	COG0582	viral genome integration into host DNA
CW753_RS14805	COG2501	S4 domain
CW753_RS14815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CW753_RS14830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CW753_RS14835	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CW753_RS14850	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CW753_RS14855	COG4181	ATPase activity
CW753_RS14860	COG2755	lipolytic protein G-D-S-L family
CW753_RS14865	COG0300	oxidoreductase activity
CW753_RS14870	COG3118	belongs to the thioredoxin family
CW753_RS14880	COG0390	transport system, permease component
CW753_RS14885	COG4619	ABC transporter
CW753_RS14890	COG0330	HflC and HflK could
CW753_RS14895	COG1585	Membrane protein implicated in regulation of membrane protease activity
CW753_RS14910	COG3735	TraB family
CW753_RS14915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CW753_RS14925	COG2223	nitrite transmembrane transporter activity
CW753_RS14930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CW753_RS14930	COG4651	solute:proton antiporter activity
CW753_RS14935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CW753_RS14975	COG2832	Protein of unknown function (DUF454)
CW753_RS14980	COG3923	Primosomal replication protein n
CW753_RS14995	COG1196	nuclear chromosome segregation
CW753_RS14995	COG3264	Mechanosensitive ion channel
CW753_RS15005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CW753_RS15010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CW753_RS15025	COG0110	maltose O-acetyltransferase activity
CW753_RS15070	COG1874	Beta-galactosidase
CW753_RS15075	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CW753_RS15080	COG3833	ABC-type maltose transport systems, permease component
CW753_RS15085	COG1175	transmembrane transport
CW753_RS15100	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CW753_RS15115	COG2364	Membrane
CW753_RS15145	COG3695	enzyme binding
CW753_RS15150	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CW753_RS15155	COG1946	Acyl-CoA thioesterase
CW753_RS15160	COG0004	ammonium transporteR
CW753_RS15165	COG0347	Belongs to the P(II) protein family
CW753_RS15170	COG1132	(ABC) transporter
CW753_RS15175	COG1132	(ABC) transporter
CW753_RS15180	COG1522	sequence-specific DNA binding
CW753_RS15195	COG4533	DNA binding
CW753_RS15205	COG0824	Thioesterase
CW753_RS15210	COG1555	photosystem II stabilization
CW753_RS15215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CW753_RS15220	COG0776	regulation of translation
CW753_RS15225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CW753_RS15255	COG0271	Belongs to the BolA IbaG family
CW753_RS15260	COG3056	Lipoprotein
CW753_RS15265	COG2223	nitrite transmembrane transporter activity
CW753_RS15270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CW753_RS15275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CW753_RS15280	COG1845	cytochrome c oxidase, subunit III
CW753_RS15285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CW753_RS15300	COG1414	Transcriptional regulator
CW753_RS15305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CW753_RS15310	COG1053	succinate dehydrogenase
CW753_RS15320	COG1053	succinate dehydrogenase
CW753_RS15335	COG0673	inositol 2-dehydrogenase activity
CW753_RS15340	COG2814	Major facilitator Superfamily
CW753_RS15350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CW753_RS15355	COG0693	protein deglycase activity
CW753_RS15375	COG0142	geranyltranstransferase activity
CW753_RS15390	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CW753_RS15395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CW753_RS15420	COG4238	major outer membrane lipoprotein
CW753_RS15440	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CW753_RS15445	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CW753_RS15450	COG1862	Preprotein translocase
CW753_RS15470	COG0450	alkyl hydroperoxide reductase
CW753_RS15475	COG3039	Transposase
CW753_RS15485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CW753_RS15500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CW753_RS15510	COG1228	amidohydrolase
CW753_RS15520	COG1335	isochorismatase
CW753_RS15525	COG0583	DNA-binding transcription factor activity
CW753_RS15530	COG0366	Alpha amylase catalytic
CW753_RS15560	COG0419	ATPase involved in DNA repair
CW753_RS15565	COG1940	carbohydrate kinase activity
CW753_RS15580	COG4126	flavin adenine dinucleotide binding
CW753_RS15590	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CW753_RS15595	COG3416	Protein conserved in bacteria
CW753_RS15615	COG1785	Belongs to the alkaline phosphatase family
CW753_RS15655	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CW753_RS15660	COG1335	isochorismatase
CW753_RS15665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CW753_RS15670	COG0113	porphobilinogen synthase activity
CW753_RS15675	COG1943	Transposase
CW753_RS15685	COG2175	clavaminate synthase activity
CW753_RS15690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CW753_RS15695	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CW753_RS15700	COG4521	taurine ABC transporter
CW753_RS15705	COG2040	homocysteine
CW753_RS15710	COG0833	amino acid
CW753_RS15720	COG4303	Ethanolamine ammonia lyase large subunit
CW753_RS15725	COG4302	ethanolamine ammonia-lyase activity
CW753_RS15760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CW753_RS15765	COG1126	abc transporter atp-binding protein
CW753_RS15770	COG4597	amino acid ABC transporter
CW753_RS15775	COG0765	amino acid transport
CW753_RS15790	COG3188	usher protein
CW753_RS15815	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CW753_RS15825	COG3639	organic phosphonate transmembrane transporter activity
CW753_RS15855	COG0791	NLP P60 protein
CW753_RS15880	COG0464	growth
CW753_RS15890	COG3093	addiction module antidote protein HigA
CW753_RS15940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CW753_RS15945	COG0022	dehydrogenase e1 component
CW753_RS15950	COG0508	dehydrogenase complex catalyzes the overall conversion of
CW753_RS15955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CW753_RS15965	COG0625	glutathione transferase activity
CW753_RS15970	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CW753_RS15990	COG0579	oxidoreductase
CW753_RS15995	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS16000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CW753_RS16005	COG1113	amino acid transport
CW753_RS16010	COG1802	Transcriptional regulator
CW753_RS16035	COG0454	-acetyltransferase
CW753_RS16055	COG2991	Protein conserved in bacteria
CW753_RS16070	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CW753_RS16075	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CW753_RS16095	COG3034	peptidoglycan biosynthetic process
CW753_RS16100	COG0121	glutamine amidotransferase
CW753_RS16110	COG1960	acyl-CoA dehydrogenase activity
CW753_RS16115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CW753_RS16125	COG0583	DNA-binding transcription factor activity
CW753_RS16135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CW753_RS16145	COG2226	methyltransferase
CW753_RS16155	COG1388	LysM domain
CW753_RS16155	COG0741	lytic transglycosylase activity
CW753_RS16160	COG2226	methyltransferase
CW753_RS16170	COG2814	Major facilitator Superfamily
CW753_RS16175	COG0583	DNA-binding transcription factor activity
CW753_RS16180	COG0656	L-ascorbic acid biosynthetic process
CW753_RS16215	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CW753_RS16225	COG2011	ABC-type metal ion transport system permease component
CW753_RS16230	COG1464	Belongs to the NlpA lipoprotein family
CW753_RS16240	COG1720	tRNA m6t6A37 methyltransferase activity
CW753_RS16250	COG0791	NLP P60 protein
CW753_RS16255	COG3015	lipoprotein NlpE involved in copper resistance
CW753_RS16260	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CW753_RS16275	COG4568	rho-dependent transcription termination
CW753_RS16285	COG0346	lactoylglutathione lyase activity
CW753_RS16290	COG1982	Orn Lys Arg decarboxylase major
CW753_RS16300	COG0587	DNA-directed DNA polymerase activity
CW753_RS16330	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CW753_RS16340	COG0750	zinc metalloprotease
CW753_RS16345	COG0575	Belongs to the CDS family
CW753_RS16360	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CW753_RS16385	COG0024	Methionine aminopeptidase
CW753_RS16390	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CW753_RS16405	COG3835	regulator
CW753_RS16410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CW753_RS16430	COG2860	membrane
CW753_RS16450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CW753_RS16455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CW753_RS16460	COG1120	ATPase activity
CW753_RS16465	COG4774	siderophore transport
CW753_RS16555	COG1643	Atp-dependent helicase
CW753_RS16560	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CW753_RS16580	COG0617	tRNA 3'-terminal CCA addition
CW753_RS16585	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CW753_RS16605	COG0726	polysaccharide deacetylase
CW753_RS16610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CW753_RS16615	COG0842	Transport permease protein
CW753_RS16620	COG1131	(ABC) transporter
CW753_RS16625	COG0288	reversible hydration of carbon dioxide
CW753_RS16635	COG4993	Dehydrogenase
CW753_RS16640	COG2132	Multicopper oxidase
CW753_RS16685	COG3064	Membrane
CW753_RS16700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CW753_RS16705	COG0508	dehydrogenase complex catalyzes the overall conversion of
CW753_RS16710	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CW753_RS16715	COG2186	Transcriptional regulator
CW753_RS16720	COG1113	amino acid transport
CW753_RS16725	COG2211	Major facilitator Superfamily
CW753_RS16730	COG3940	Belongs to the glycosyl hydrolase 43 family
CW753_RS16735	COG3725	Membrane protein required for beta-lactamase induction
CW753_RS16740	COG3023	N-Acetylmuramoyl-L-alanine amidase
CW753_RS16750	COG4969	Belongs to the N-Me-Phe pilin family
CW753_RS16755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CW753_RS16760	COG1459	type II secretion system
CW753_RS16785	COG0494	nUDIX hydrolase
CW753_RS16805	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CW753_RS16810	COG0849	cell division
CW753_RS16835	COG0772	Belongs to the SEDS family
CW753_RS16850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CW753_RS16855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CW753_RS16860	COG0768	penicillin binding
CW753_RS16880	COG1609	Transcriptional regulator
CW753_RS16890	COG0028	Belongs to the TPP enzyme family
CW753_RS16940	COG0738	Major facilitator superfamily
CW753_RS16955	COG2271	Major facilitator Superfamily
CW753_RS16960	COG2814	Major facilitator Superfamily
CW753_RS16980	COG1178	ABC-type Fe3 transport system permease component
CW753_RS16990	COG0586	Pfam SNARE associated Golgi protein
CW753_RS17010	COG0235	Class ii aldolase
CW753_RS17015	COG0417	DNA replication proofreading
CW753_RS17025	COG0564	pseudouridine synthase activity
CW753_RS17040	COG3493	citrate carrier protein
CW753_RS17055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CW753_RS17070	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CW753_RS17125	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CW753_RS17150	COG1047	Peptidyl-prolyl cis-trans
CW753_RS17165	COG0196	riboflavin kinase activity
CW753_RS17180	COG0583	DNA-binding transcription factor activity
CW753_RS17205	COG4735	regulation of single-species biofilm formation
CW753_RS17210	COG1584	GPR1 FUN34 yaaH family protein
CW753_RS17215	COG0477	Major facilitator Superfamily
CW753_RS17220	COG0521	Mo-molybdopterin cofactor biosynthetic process
CW753_RS17225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CW753_RS17250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CW753_RS17260	COG0527	aspartate kinase activity
CW753_RS17260	COG0460	homoserine dehydrogenase
CW753_RS17270	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CW753_RS17280	COG0745	RESPONSE REGULATOR receiver
CW753_RS17285	COG4452	Inner membrane protein CreD
CW753_RS17290	COG2205	protein histidine kinase activity
CW753_RS17295	COG0745	RESPONSE REGULATOR receiver
CW753_RS17300	COG3045	CreA protein
CW753_RS17305	COG3708	Transcriptional regulator
CW753_RS17305	COG2207	Transcriptional regulator
CW753_RS17325	COG0741	lytic transglycosylase activity
CW753_RS17330	COG0488	(ABC) transporter
CW753_RS17340	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CW753_RS17345	COG0560	Phosphoserine phosphatase
CW753_RS17355	COG3726	membrane protein affecting hemolysin expression
CW753_RS17385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CW753_RS17390	COG0084	hydrolase, TatD family'
CW753_RS17395	COG4667	esterase of the alpha-beta hydrolase superfamily
CW753_RS17405	COG2823	Periplasmic or secreted lipoprotein
CW753_RS17415	COG1011	Hydrolase
CW753_RS17420	COG0456	acetyltransferase
CW753_RS17425	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CW753_RS17455	COG3706	GGDEF domain
CW753_RS17460	COG4114	ferric iron reductase
CW753_RS17465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CW753_RS17465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CW753_RS17470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CW753_RS17475	COG2197	response regulator
CW753_RS17480	COG2197	response regulator
CW753_RS17500	COG2966	Psort location CytoplasmicMembrane, score
CW753_RS17515	COG1484	DNA-dependent DNA replication
CW753_RS17530	COG3436	PFAM IS66 Orf2 family protein
CW753_RS17535	COG4372	Transposase
CW753_RS17545	COG5464	transposase or invertase
CW753_RS17555	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CW753_RS17560	COG3716	PTS system mannose fructose sorbose family IID component
CW753_RS17565	COG3715	PTS system
CW753_RS17580	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CW753_RS17580	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CW753_RS17590	COG1063	alcohol dehydrogenase
CW753_RS17595	COG1802	Transcriptional regulator
CW753_RS17600	COG2271	Major facilitator Superfamily
CW753_RS17605	COG0456	acetyltransferase
CW753_RS17605	COG1214	PFAM Peptidase M22, glycoprotease
CW753_RS17620	COG1737	Transcriptional regulator
CW753_RS17625	COG0800	Aldolase
CW753_RS17630	COG3734	2-keto-3-deoxy-galactonokinase
CW753_RS17645	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CW753_RS17675	COG1846	Transcriptional regulator
CW753_RS17680	COG0179	Fumarylacetoacetate (FAA) hydrolase
CW753_RS17690	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS17695	COG3384	dioxygenase
CW753_RS17705	COG3971	2-oxopent-4-enoate hydratase activity
CW753_RS17725	COG2368	4-hydroxyphenylacetate
CW753_RS17730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CW753_RS17735	COG1966	Carbon starvation protein
CW753_RS17740	COG2879	small protein
CW753_RS17745	COG0523	cobalamin synthesis protein
CW753_RS17755	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS17765	COG1917	Cupin 2, conserved barrel domain protein
CW753_RS17765	COG2207	Transcriptional regulator
CW753_RS17775	COG2733	membrane
CW753_RS17790	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CW753_RS17795	COG1924	4 iron, 4 sulfur cluster binding
CW753_RS17810	COG1566	PFAM secretion protein HlyD family protein
CW753_RS17820	COG5457	Domain of unknown function (DUF1127)
CW753_RS17825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CW753_RS17835	COG0583	DNA-binding transcription factor activity
CW753_RS17840	COG2249	NAD(P)H dehydrogenase (quinone) activity
CW753_RS17850	COG1172	Belongs to the binding-protein-dependent transport system permease family
CW753_RS17855	COG1129	ABC transporter
CW753_RS17860	COG1879	ABC-type sugar transport system periplasmic component
CW753_RS17870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CW753_RS17875	COG0842	Transport permease protein
CW753_RS17875	COG1129	ABC transporter
CW753_RS17880	COG0842	Transport permease protein
CW753_RS17910	COG2850	peptidyl-arginine hydroxylation
CW753_RS17925	COG5002	protein histidine kinase activity
CW753_RS17930	COG0745	RESPONSE REGULATOR receiver
CW753_RS17940	COG1538	Outer membrane efflux protein
CW753_RS17945	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CW753_RS17950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CW753_RS17955	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CW753_RS17965	COG3040	lipid binding
CW753_RS17970	COG0789	Transcriptional regulator
CW753_RS17975	COG3631	Ketosteroid isomerase-related protein
CW753_RS17980	COG0300	oxidoreductase activity
CW753_RS17995	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CW753_RS18015	COG3272	Protein of unknown function (DUF1722)
CW753_RS18020	COG4580	involved in the transport of maltose and maltodextrins
CW753_RS18030	COG2211	Major facilitator Superfamily
CW753_RS18035	COG3507	Belongs to the glycosyl hydrolase 43 family
CW753_RS18055	COG1216	Glycosyl transferase, family 2
CW753_RS18155	COG3039	Transposase
CW753_RS18170	COG0582	viral genome integration into host DNA
CW753_RS18185	COG0288	reversible hydration of carbon dioxide
CW753_RS18190	COG0659	secondary active sulfate transmembrane transporter activity
CW753_RS18195	COG1064	alcohol dehydrogenase
CW753_RS18200	COG1175	transmembrane transport
CW753_RS18205	COG0395	ABC-type sugar transport system, permease component
CW753_RS18210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CW753_RS18215	COG3842	ATPase activity
CW753_RS18230	COG1082	Xylose isomerase domain protein TIM barrel
CW753_RS18240	COG3962	Belongs to the TPP enzyme family
CW753_RS18245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CW753_RS18250	COG0837	glucose binding
CW753_RS18250	COG1737	Transcriptional regulator
CW753_RS18275	COG3718	enzyme involved in inositol metabolism
CW753_RS18290	COG0433	COG0433 Predicted ATPase
CW753_RS18295	COG0795	lipopolysaccharide-transporting ATPase activity
CW753_RS18300	COG0795	lipopolysaccharide-transporting ATPase activity
CW753_RS18315	COG2927	DNA polymerase III (CHI subunit)
CW753_RS18320	COG0525	valine-tRNA ligase activity
CW753_RS18345	COG2188	Transcriptional regulator
CW753_RS18350	COG1288	antiporter activity
CW753_RS18355	COG1228	amidohydrolase
CW753_RS18360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CW753_RS18365	COG2222	sugar isomerase
CW753_RS18370	COG2731	YhcH YjgK YiaL family protein
CW753_RS18415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CW753_RS18415	COG1263	PTS System
CW753_RS18420	COG0366	Alpha amylase catalytic
CW753_RS18425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CW753_RS18430	COG1486	melibiose metabolic process
CW753_RS18450	COG0602	queuosine metabolic process
CW753_RS18455	COG2026	Addiction module toxin, RelE StbE family
CW753_RS18460	COG3077	Addiction module antitoxin, RelB DinJ family
CW753_RS18465	COG3711	transcriptional antiterminator
CW753_RS18465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CW753_RS18470	COG2706	6-phosphogluconolactonase activity
CW753_RS18485	COG3964	amidohydrolase
CW753_RS18520	COG0312	modulator of DNA gyrase
CW753_RS18540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CW753_RS18550	COG1172	Belongs to the binding-protein-dependent transport system permease family
CW753_RS18555	COG1172	Belongs to the binding-protein-dependent transport system permease family
CW753_RS18560	COG1129	ABC transporter
CW753_RS18565	COG1879	ABC-type sugar transport system periplasmic component
CW753_RS18585	COG2105	PFAM AIG2 family protein
CW753_RS18590	COG2911	Protein conserved in bacteria
CW753_RS18595	COG0729	surface antigen
CW753_RS18605	COG1253	flavin adenine dinucleotide binding
CW753_RS18620	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CW753_RS18635	COG1733	regulation of RNA biosynthetic process
CW753_RS18640	COG0702	epimerase
CW753_RS18650	COG0697	spore germination
CW753_RS18660	COG1113	amino acid transport
CW753_RS18665	COG0545	Peptidyl-prolyl cis-trans isomerase
CW753_RS18670	COG3061	Opacity-associated protein A
CW753_RS18680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CW753_RS18685	COG2965	DNA replication, synthesis of RNA primer
CW753_RS18745	COG1073	alpha beta
CW753_RS18750	COG3650	response to hydrogen peroxide
CW753_RS18760	COG1960	acyl-CoA dehydrogenase activity
CW753_RS18765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CW753_RS18770	COG0557	exoribonuclease II activity
CW753_RS18785	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CW753_RS18800	COG0330	HflC and HflK could
CW753_RS18805	COG0330	HflC and HflK could
CW753_RS18810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CW753_RS18830	COG0860	N-Acetylmuramoyl-L-alanine amidase
CW753_RS18835	COG0802	atpase or kinase
CW753_RS18840	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CW753_RS18840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CW753_RS18845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CW753_RS18870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CW753_RS18895	COG3264	Mechanosensitive ion channel
CW753_RS18895	COG1511	domain protein
CW753_RS18910	COG1053	succinate dehydrogenase
CW753_RS18915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CW753_RS18935	COG2076	Multidrug Resistance protein
CW753_RS18940	COG5510	response to toxic substance
CW753_RS18955	COG1509	lysine 2,3-aminomutase activity
CW753_RS18960	COG0745	RESPONSE REGULATOR receiver
CW753_RS19020	COG3539	Fimbrial protein
CW753_RS19045	COG0531	amino acid
CW753_RS19050	COG3030	protein affecting phage T7 exclusion by the F plasmid
CW753_RS19060	COG1027	Aspartate ammonia-lyase
CW753_RS19065	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CW753_RS19080	COG1309	transcriptional regulator
CW753_RS19095	COG0582	viral genome integration into host DNA
CW753_RS19135	COG1397	ADP-ribosylglycohydrolase
CW753_RS19145	COG0582	viral genome integration into host DNA
CW753_RS19155	COG2003	Belongs to the UPF0758 family
CW753_RS19185	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CW753_RS19190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CW753_RS19255	COG3596	GTP binding
CW753_RS19305	COG2003	Belongs to the UPF0758 family
CW753_RS19355	COG0457	Tetratricopeptide repeat
CW753_RS19360	COG0726	polysaccharide deacetylase
CW753_RS19360	COG1649	PFAM Uncharacterised BCR, COG1649
CW753_RS19365	COG1215	transferase activity, transferring glycosyl groups
CW753_RS19385	COG0861	Integral membrane protein TerC family
CW753_RS19420	COG1486	melibiose metabolic process
CW753_RS19430	COG2169	Transcriptional regulator
CW753_RS19445	COG2824	Alkylphosphonate utilization operon protein PhnA
CW753_RS19450	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CW753_RS19455	COG2188	Transcriptional regulator
CW753_RS19460	COG3624	Phosphonate C-P lyase system protein PhnG
CW753_RS19465	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CW753_RS19470	COG3626	phosphonate metabolism
CW753_RS19475	COG3627	carbon phosphorus lyase activity
CW753_RS19480	COG4107	phosphonate C-P lyase system protein PhnK
CW753_RS19485	COG4778	phosphonate C-P lyase system protein PhnL
CW753_RS19490	COG3454	Phosphonate metabolism
CW753_RS19500	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CW753_RS19510	COG4191	Histidine kinase
CW753_RS19510	COG0784	Response regulator, receiver
CW753_RS19515	COG1129	ABC transporter
CW753_RS19520	COG1172	Belongs to the binding-protein-dependent transport system permease family
CW753_RS19555	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CW753_RS19560	COG1301	dicarboxylic acid transport
CW753_RS19570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CW753_RS19580	COG3162	membrane
CW753_RS19610	COG3539	Fimbrial protein
CW753_RS19615	COG1346	cytolysis
CW753_RS19620	COG1380	Effector of murein hydrolase LrgA
CW753_RS19625	COG0583	DNA-binding transcription factor activity
CW753_RS19630	COG0025	NhaP-type Na H and K H
CW753_RS19635	COG2252	PERMEase
CW753_RS19640	COG0625	glutathione transferase activity
CW753_RS19645	COG0789	Transcriptional regulator
CW753_RS19655	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CW753_RS19690	COG1234	tRNA 3'-trailer cleavage
CW753_RS19695	COG1609	Transcriptional regulator
CW753_RS19700	COG0483	inositol monophosphate 1-phosphatase activity
CW753_RS19720	COG3039	Transposase
CW753_RS19740	COG4771	TonB-dependent receptor
CW753_RS19745	COG0741	lytic transglycosylase activity
CW753_RS19765	COG2315	Protein conserved in bacteria
CW753_RS19770	COG0432	Pfam Uncharacterised protein family UPF0047
CW753_RS19790	COG0305	Participates in initiation and elongation during chromosome replication
CW753_RS19805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CW753_RS19815	COG0735	belongs to the Fur family
CW753_RS19820	COG3237	CsbD-like
CW753_RS19825	COG0534	Mate efflux family protein
CW753_RS19835	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CW753_RS19900	COG3039	Transposase
CW753_RS19915	COG0251	oxidation-reduction process
CW753_RS19925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CW753_RS19945	COG0527	aspartate kinase activity
CW753_RS19995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CW753_RS20005	COG0456	acetyltransferase
CW753_RS20035	COG0151	Belongs to the GarS family
CW753_RS20045	COG4191	Histidine kinase
CW753_RS20050	COG3678	ATP-independent chaperone mediated protein folding
CW753_RS20085	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CW753_RS20100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CW753_RS20105	COG2104	thiamine diphosphate biosynthetic process
CW753_RS20130	COG1447	Phosphotransferase system cellobiose-specific component IIA
CW753_RS20135	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CW753_RS20170	COG0250	Participates in transcription elongation, termination and antitermination
CW753_RS20220	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CW753_RS20250	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CW753_RS20260	COG1739	Uncharacterized protein family UPF0029
CW753_RS20305	COG0805	protein transport
CW753_RS20325	COG3165	ubiquinone biosynthetic process from chorismate
CW753_RS20355	COG0583	DNA-binding transcription factor activity
CW753_RS20360	COG0697	spore germination
CW753_RS20365	COG0561	phosphatase activity
CW753_RS20370	COG2267	carboxylic ester hydrolase activity
CW753_RS20375	COG1280	lysine exporter protein (LysE YggA)
CW753_RS20420	COG0210	DNA helicase
CW753_RS20425	COG1011	Hydrolase
CW753_RS20455	COG3072	Adenylate cyclase
CW753_RS20470	COG2959	enzyme of heme biosynthesis
CW753_RS20475	COG3071	HemY protein
CW753_RS20520	COG2244	polysaccharide biosynthetic process
CW753_RS20525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CW753_RS20530	COG0456	acetyltransferase
CW753_RS20535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CW753_RS20540	COG1088	dTDP-glucose 4,6-dehydratase activity
CW753_RS20545	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CW753_RS20550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CW753_RS20560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CW753_RS20575	COG3118	belongs to the thioredoxin family
CW753_RS20605	COG1811	Na channel or pump
CW753_RS20615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CW753_RS20620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CW753_RS20630	COG0583	DNA-binding transcription factor activity
CW753_RS20635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CW753_RS20650	COG3978	acetolactate synthase activity
CW753_RS20670	COG3085	chromosome segregation
CW753_RS20745	COG0583	DNA-binding transcription factor activity
CW753_RS20770	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CW753_RS20785	COG3443	Belongs to the bacterial solute-binding protein 9 family
CW753_RS20800	COG0371	Dehydrogenase
CW753_RS20805	COG0697	spore germination
CW753_RS20815	COG0583	DNA-binding transcription factor activity
CW753_RS20835	COG0527	aspartate kinase activity
CW753_RS20835	COG0460	homoserine dehydrogenase
CW753_RS20840	COG0626	cystathionine gamma-synthase activity
CW753_RS20855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CW753_RS20860	COG1609	Transcriptional regulator
CW753_RS20865	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CW753_RS20900	COG3678	ATP-independent chaperone mediated protein folding
CW753_RS20905	COG0745	RESPONSE REGULATOR receiver
CW753_RS20910	COG2205	protein histidine kinase activity
CW753_RS20915	COG2258	MOSC domain
CW753_RS20920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CW753_RS20965	COG1129	ABC transporter
CW753_RS20970	COG1172	Belongs to the binding-protein-dependent transport system permease family
CW753_RS20975	COG1172	Belongs to the binding-protein-dependent transport system permease family
CW753_RS20980	COG1454	alcohol dehydrogenase
CW753_RS20990	COG2211	Major facilitator Superfamily
CW753_RS21065	COG3383	formate dehydrogenase (NAD+) activity
CW753_RS21065	COG0243	molybdopterin cofactor binding
CW753_RS21070	COG3383	formate dehydrogenase (NAD+) activity
CW753_RS21070	COG0243	molybdopterin cofactor binding
CW753_RS21075	COG0437	4 iron, 4 sulfur cluster binding
CW753_RS21080	COG2864	formate dehydrogenase
CW753_RS21095	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CW753_RS21105	COG0456	acetyltransferase
CW753_RS21120	COG1011	Hydrolase
CW753_RS21135	COG3852	Histidine kinase
CW753_RS21145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CW753_RS21175	COG0204	Acyl-transferase
CW753_RS21185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CW753_RS21190	COG3084	Protein conserved in bacteria
CW753_RS21200	COG1763	Mo-molybdopterin cofactor biosynthetic process
CW753_RS21230	COG2186	Transcriptional regulator
CW753_RS21235	COG0477	Major facilitator Superfamily
CW753_RS21240	COG1609	Transcriptional regulator
CW753_RS21245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CW753_RS21255	COG1172	Belongs to the binding-protein-dependent transport system permease family
CW753_RS21260	COG1129	ABC transporter
CW753_RS21290	COG1522	sequence-specific DNA binding
CW753_RS21295	COG0716	FMN binding
CW753_RS21310	COG3312	ion transport
CW753_RS21365	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CW753_RS21370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CW753_RS21375	COG0573	inorganic phosphate transmembrane transporter activity
CW753_RS21380	COG0581	inorganic phosphate transmembrane transporter activity
CW753_RS21385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CW753_RS21390	COG0704	Plays a role in the regulation of phosphate uptake
CW753_RS21405	COG2382	esterase
CW753_RS21410	COG0363	glucosamine-6-phosphate deaminase activity
CW753_RS21415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CW753_RS21425	COG2252	PERMEase
CW753_RS21430	COG0431	NADPH-dependent FMN reductase
CW753_RS21435	COG2091	lysine biosynthetic process via aminoadipic acid
CW753_RS21465	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CW753_RS21495	COG0187	DNA topoisomerase II activity
CW753_RS21500	COG0561	phosphatase activity
CW753_RS21515	COG2186	Transcriptional regulator
CW753_RS21520	COG3734	2-keto-3-deoxy-galactonokinase
CW753_RS21525	COG0800	Aldolase
CW753_RS21535	COG2271	Major facilitator Superfamily
CW753_RS21545	COG5645	(Lipo)protein
CW753_RS21560	COG3645	SOS response
CW753_RS21570	COG2188	Transcriptional regulator
CW753_RS21585	COG2149	membrane
CW753_RS21605	COG2610	gluconate transmembrane transporter activity
CW753_RS21610	COG0583	DNA-binding transcription factor activity
CW753_RS21615	COG2814	Major facilitator Superfamily
CW753_RS21640	COG0028	Belongs to the TPP enzyme family
CW753_RS21645	COG0440	acetolactate synthase activity
CW753_RS21650	COG2197	response regulator
CW753_RS21660	COG2271	Major facilitator Superfamily
CW753_RS21715	COG2188	Transcriptional regulator
CW753_RS21740	COG4580	involved in the transport of maltose and maltodextrins
CW753_RS21745	COG1447	Phosphotransferase system cellobiose-specific component IIA
CW753_RS21750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CW753_RS21750	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CW753_RS21760	COG1609	Transcriptional regulator
CW753_RS21770	COG0583	DNA-binding transcription factor activity
CW753_RS21775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CW753_RS21780	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CW753_RS21785	COG2828	Protein conserved in bacteria
CW753_RS21800	COG0697	spore germination
CW753_RS21805	COG1263	PTS System
CW753_RS21805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CW753_RS21815	COG2814	Major facilitator Superfamily
CW753_RS21825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CW753_RS21855	COG0583	DNA-binding transcription factor activity
CW753_RS21880	COG1464	Belongs to the NlpA lipoprotein family
CW753_RS21895	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CW753_RS21905	COG1064	alcohol dehydrogenase
CW753_RS21940	COG2211	Major facilitator Superfamily
CW753_RS21945	COG1501	Belongs to the glycosyl hydrolase 31 family
CW753_RS21955	COG1486	melibiose metabolic process
CW753_RS21960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CW753_RS21960	COG1263	PTS System
CW753_RS21965	COG2982	Protein involved in outer membrane biogenesis
CW753_RS21970	COG2233	PERMEase
CW753_RS21975	COG0786	glutamate:sodium symporter activity
CW753_RS21995	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CW753_RS22020	COG3152	Membrane
CW753_RS22030	COG1494	fructose-1,6-bisphosphatase
CW753_RS22035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CW753_RS22040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CW753_RS22045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CW753_RS22065	COG2860	membrane
CW753_RS22075	COG2169	Transcriptional regulator
CW753_RS22075	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CW753_RS22080	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CW753_RS22085	COG1561	YicC-like family, N-terminal region
CW753_RS22115	COG1131	(ABC) transporter
CW753_RS22120	COG0842	Transport permease protein
CW753_RS22150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CW753_RS22185	COG1519	Transferase
CW753_RS22190	COG1216	Glycosyl transferase, family 2
CW753_RS22195	COG0438	transferase activity, transferring glycosyl groups
CW753_RS22205	COG0859	PFAM glycosyl transferase family 9
CW753_RS22230	COG0859	PFAM glycosyl transferase family 9
CW753_RS22245	COG0156	8-amino-7-oxononanoate synthase activity
CW753_RS22255	COG0463	Glycosyl transferase, family 2
CW753_RS22260	COG2861	carbohydrate metabolic process
CW753_RS22265	COG4942	peptidase
CW753_RS22275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CW753_RS22280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CW753_RS22300	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CW753_RS22310	COG2186	Transcriptional regulator
CW753_RS22330	COG3722	fumarate hydratase activity
CW753_RS22350	COG1566	PFAM secretion protein HlyD family protein
CW753_RS22355	COG0625	glutathione transferase activity
CW753_RS22365	COG3276	selenocysteine insertion sequence binding
CW753_RS22370	COG1414	Transcriptional regulator
CW753_RS22375	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CW753_RS22380	COG3977	Valine--pyruvate aminotransferase
CW753_RS22385	COG0366	Alpha amylase catalytic
CW753_RS22390	COG2992	FlgJ-related protein
CW753_RS22395	COG1609	Transcriptional regulator
CW753_RS22395	COG2207	Transcriptional regulator
CW753_RS22400	COG4214	carbohydrate transport
CW753_RS22410	COG4213	ABC transporter substrate-binding protein
CW753_RS22430	COG4682	membrane
CW753_RS22435	COG4682	membrane
CW753_RS22440	COG3274	enterobacterial common antigen metabolic process
CW753_RS22480	COG1278	Cold shock
CW753_RS22485	COG2944	sequence-specific DNA binding
CW753_RS22490	COG2814	Major facilitator Superfamily
CW753_RS22515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CW753_RS22525	COG1609	Transcriptional regulator
CW753_RS22530	COG2885	chlorophyll binding
CW753_RS22535	COG0243	molybdopterin cofactor binding
CW753_RS22540	COG0456	acetyltransferase
CW753_RS22545	COG2818	Glycosylase
CW753_RS22550	COG5571	outer membrane autotransporter
CW753_RS22555	COG2223	nitrite transmembrane transporter activity
CW753_RS22595	COG0747	negative chemotaxis
CW753_RS22600	COG0601	transmembrane transport
CW753_RS22605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CW753_RS22610	COG0444	Belongs to the ABC transporter superfamily
CW753_RS22615	COG4608	Belongs to the ABC transporter superfamily
CW753_RS22625	COG0457	Tetratricopeptide repeat
CW753_RS22625	COG3118	belongs to the thioredoxin family
CW753_RS22630	COG2200	EAL domain
CW753_RS22630	COG2199	diguanylate cyclase activity
CW753_RS22640	COG0612	Peptidase, M16
CW753_RS22655	COG2982	Protein involved in outer membrane biogenesis
CW753_RS22660	COG0477	Major facilitator Superfamily
CW753_RS22665	COG1295	ribonuclease BN
CW753_RS22675	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS22680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CW753_RS22690	COG1454	alcohol dehydrogenase
CW753_RS22700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CW753_RS22705	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CW753_RS22710	COG0671	phosphoesterase, PA-phosphatase related
CW753_RS22730	COG0589	response to stress
CW753_RS22740	COG0306	phosphate transporter
CW753_RS22745	COG2081	HI0933 family
CW753_RS22750	COG2239	Acts as a magnesium transporter
CW753_RS22760	COG1124	(ABC) transporter
CW753_RS22770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CW753_RS22775	COG0601	transmembrane transport
CW753_RS22780	COG0747	negative chemotaxis
CW753_RS22795	COG3479	Phenolic acid decarboxylase
CW753_RS22840	COG0477	Major facilitator Superfamily
CW753_RS22850	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CW753_RS22865	COG3714	YhhN family
CW753_RS22875	COG3776	membrane
CW753_RS22880	COG0742	ribosomal rna small subunit methyltransferase
CW753_RS22885	COG0552	protein localization to endoplasmic reticulum
CW753_RS22890	COG2884	Cell division ATP-binding protein ftsE
CW753_RS22895	COG2177	Part of the ABC transporter FtsEX involved in
CW753_RS22910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CW753_RS22920	COG0683	leucine binding
CW753_RS22935	COG0683	leucine binding
CW753_RS22940	COG0559	Belongs to the binding-protein-dependent transport system permease family
CW753_RS22990	COG0584	glycerophosphoryl diester phosphodiesterase
CW753_RS23000	COG0405	Gamma-glutamyltransferase
CW753_RS23005	COG1247	-acetyltransferase
CW753_RS23015	COG0673	inositol 2-dehydrogenase activity
CW753_RS23020	COG1741	Belongs to the pirin family
CW753_RS23025	COG1609	Transcriptional regulator
CW753_RS23030	COG3265	gluconokinase activity
CW753_RS23035	COG2610	gluconate transmembrane transporter activity
CW753_RS23045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CW753_RS23070	COG0058	SHG alpha-glucan phosphorylase activity
CW753_RS23085	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CW753_RS23100	COG1349	DNA-binding transcription factor activity
CW753_RS23115	COG0058	SHG alpha-glucan phosphorylase activity
CW753_RS23120	COG1640	4-alpha-glucanotransferase
CW753_RS23125	COG2610	gluconate transmembrane transporter activity
CW753_RS23160	COG1918	ferrous iron import across plasma membrane
CW753_RS23165	COG2183	response to ionizing radiation
CW753_RS23170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CW753_RS23195	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CW753_RS23200	COG1011	Hydrolase
CW753_RS23210	COG0494	nUDIX hydrolase
CW753_RS23240	COG4796	Type ii and iii secretion system protein
CW753_RS23260	COG3266	domain, Protein
CW753_RS23265	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CW753_RS23270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CW753_RS23295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CW753_RS23300	COG0402	S-adenosylhomocysteine deaminase activity
CW753_RS23305	COG0738	Major facilitator superfamily
CW753_RS23330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CW753_RS23335	COG1289	transmembrane transporter activity
CW753_RS23345	COG1765	OsmC-like protein
CW753_RS23350	COG3954	Phosphoribulokinase
CW753_RS23360	COG0429	hydrolase of the alpha beta-hydrolase fold
CW753_RS23370	COG0488	(ABC) transporter
CW753_RS23385	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CW753_RS23390	COG1047	Peptidyl-prolyl cis-trans
CW753_RS23400	COG0545	Peptidyl-prolyl cis-trans isomerase
CW753_RS23405	COG2964	Protein conserved in bacteria
CW753_RS23460	COG0051	transcription antitermination factor activity, RNA binding
CW753_RS23485	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CW753_RS23500	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CW753_RS23565	COG0201	protein transport
CW753_RS23590	COG0202	RNA polymerase activity
CW753_RS23605	COG0789	Transcriptional regulator
CW753_RS23610	COG3036	rescue of stalled ribosome
CW753_RS23640	COG0758	DNA mediated transformation
CW753_RS23650	COG0551	DNA topoisomerase type I activity
CW753_RS23670	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CW753_RS23705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CW753_RS23710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CW753_RS23715	COG1309	transcriptional regulator
CW753_RS23740	COG4145	pantothenate transmembrane transporter activity
CW753_RS23745	COG3924	membrane
CW753_RS23750	COG0439	Biotin carboxylase
CW753_RS23755	COG0511	ligase activity, forming carbon-carbon bonds
CW753_RS23780	COG2199	diguanylate cyclase activity
CW753_RS23780	COG2200	EAL domain
CW753_RS23785	COG1077	Cell shape determining protein MreB Mrl
CW753_RS23790	COG1792	Involved in formation and maintenance of cell shape
CW753_RS23795	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CW753_RS23805	COG1530	ribonuclease E activity
CW753_RS23810	COG3164	Protein of unknown function
CW753_RS23815	COG0312	modulator of DNA gyrase
CW753_RS23820	COG0583	DNA-binding transcription factor activity
CW753_RS23835	COG1289	transmembrane transporter activity
CW753_RS23840	COG2732	(Barnase) inhibitor
CW753_RS23865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CW753_RS23870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CW753_RS23875	COG3105	Protein conserved in bacteria
CW753_RS23880	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CW753_RS23900	COG0625	glutathione transferase activity
CW753_RS23905	COG2969	positive regulation of protein catabolic process
CW753_RS23915	COG0493	'glutamate synthase
CW753_RS23920	COG0070	glutamate synthase
CW753_RS23920	COG0067	glutamate synthase
CW753_RS23920	COG0069	glutamate synthase activity
CW753_RS23925	COG1242	4 iron, 4 sulfur cluster binding
CW753_RS23930	COG2271	Major facilitator Superfamily
CW753_RS23935	COG1063	alcohol dehydrogenase
CW753_RS23940	COG1312	Catalyzes the dehydration of D-mannonate
CW753_RS23945	COG2198	Histidine kinase
CW753_RS23945	COG5002	protein histidine kinase activity
CW753_RS23945	COG0784	Response regulator, receiver
CW753_RS23950	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CW753_RS23955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CW753_RS23960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CW753_RS23970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CW753_RS23975	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CW753_RS23980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CW753_RS23985	COG1137	ATPase activity
CW753_RS23990	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CW753_RS23995	COG3117	lipopolysaccharide transmembrane transporter activity
CW753_RS24000	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CW753_RS24010	COG0530	calcium, potassium:sodium antiporter activity
CW753_RS24020	COG1127	ABC transporter
CW753_RS24025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CW753_RS24030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CW753_RS24035	COG2854	intermembrane phospholipid transfer
CW753_RS24040	COG3113	response to antibiotic
CW753_RS24045	COG5007	Belongs to the BolA IbaG family
CW753_RS24055	COG3423	Transcriptional regulator
CW753_RS24060	COG0142	geranyltranstransferase activity
CW753_RS24075	COG0697	spore germination
CW753_RS24085	COG2027	D-alanyl-D-alanine carboxypeptidase
CW753_RS24095	COG1534	Rna-binding protein
CW753_RS24105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CW753_RS24110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CW753_RS24120	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CW753_RS24160	COG0195	Participates in both transcription termination and antitermination
CW753_RS24210	COG0814	amino acid
CW753_RS24235	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CW753_RS24280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CW753_RS24285	COG0826	peptidase U32
CW753_RS24290	COG0826	peptidase U32
CW753_RS24295	COG3154	lipid carrier protein
CW753_RS24300	COG3153	acetyltransferase
CW753_RS24315	COG0693	protein deglycase activity
CW753_RS24320	COG0702	epimerase
CW753_RS24325	COG0701	Predicted permease
CW753_RS24330	COG2823	Periplasmic or secreted lipoprotein
CW753_RS24350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CW753_RS24355	COG2721	sulfolactate sulfo-lyase activity
CW753_RS24365	COG2271	Major facilitator Superfamily
CW753_RS24375	COG2084	Dehydrogenase
CW753_RS24380	COG1929	Belongs to the glycerate kinase type-1 family
CW753_RS24405	COG1741	Belongs to the pirin family
CW753_RS24410	COG0583	DNA-binding transcription factor activity
CW753_RS24415	COG3152	Membrane
CW753_RS24420	COG0435	Glutathione S-transferase
CW753_RS24425	COG2259	Doxx family
CW753_RS24435	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CW753_RS24440	COG4575	ribosome binding
CW753_RS24445	COG1422	Protein of unknown function (DUF1090)
CW753_RS24455	COG0586	Pfam SNARE associated Golgi protein
CW753_RS24460	COG2186	Transcriptional regulator
CW753_RS24465	COG2271	Major facilitator Superfamily
CW753_RS24475	COG2721	sulfolactate sulfo-lyase activity
CW753_RS24490	COG0861	Integral membrane protein TerC family
CW753_RS24495	COG0673	inositol 2-dehydrogenase activity
CW753_RS24500	COG1451	nucleotide metabolic process
CW753_RS24570	COG1695	Transcriptional regulator
CW753_RS24590	COG1461	Dihydroxyacetone kinase
CW753_RS24595	COG2376	Dihydroxyacetone kinase
CW753_RS24680	COG3039	Transposase
CW753_RS24685	COG3247	response to pH
CW753_RS24695	COG2205	protein histidine kinase activity
CW753_RS24695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CW753_RS24695	COG2198	Histidine kinase
CW753_RS24695	COG0784	Response regulator, receiver
CW753_RS24700	COG2197	response regulator
CW753_RS24725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CW753_RS24730	COG0358	DNA primase activity
CW753_RS24735	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CW753_RS24795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CW753_RS24810	COG4991	sh3 domain protein
CW753_RS24815	COG3025	triphosphatase activity
CW753_RS24835	COG2960	long-chain fatty acid transporting porin activity
CW753_RS24850	COG3384	dioxygenase
CW753_RS24855	COG0754	glutathionylspermidine amidase activity
CW753_RS24870	COG0494	nUDIX hydrolase
CW753_RS24875	COG3151	Protein conserved in bacteria
CW753_RS24880	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CW753_RS24885	COG3150	esterase
CW753_RS24895	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CW753_RS24900	COG2249	NAD(P)H dehydrogenase (quinone) activity
CW753_RS24905	COG0642	Histidine kinase
CW753_RS24915	COG3111	PFAM Bacterial OB fold (BOF) protein
CW753_RS24920	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CW753_RS24925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CW753_RS24930	COG0204	Acyl-transferase
CW753_RS24935	COG2132	Multicopper oxidase
CW753_RS24940	COG1032	radical SAM domain protein
CW753_RS24950	COG0656	L-ascorbic acid biosynthetic process
CW753_RS24955	COG1979	alcohol dehydrogenase
CW753_RS24960	COG2207	Transcriptional regulator
CW753_RS24965	COG0586	Pfam SNARE associated Golgi protein
CW753_RS24970	COG0626	cystathionine gamma-synthase activity
CW753_RS24980	COG0848	biopolymer transport protein
CW753_RS24985	COG2211	Major facilitator Superfamily
CW753_RS25010	COG0625	glutathione transferase activity
CW753_RS25020	COG0754	glutathionylspermidine amidase activity
CW753_RS25025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CW753_RS25045	COG0583	DNA-binding transcription factor activity
CW753_RS25050	COG0626	cystathionine gamma-synthase activity
CW753_RS25075	COG3423	Transcriptional regulator
CW753_RS25090	COG0582	viral genome integration into host DNA
CW753_RS25100	COG1811	Na channel or pump
CW753_RS25110	COG1982	Orn Lys Arg decarboxylase major
CW753_RS25115	COG2211	Major facilitator Superfamily
CW753_RS25130	COG1194	a g-specific adenine glycosylase
CW753_RS25140	COG3171	Protein conserved in bacteria
CW753_RS25150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CW753_RS25165	COG0762	integral membrane protein
CW753_RS25170	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CW753_RS25175	COG2805	Type II/IV secretion system protein
CW753_RS25200	COG0189	ligase activity
CW753_RS25205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CW753_RS25210	COG2356	endonuclease I
CW753_RS25220	COG2814	Major facilitator Superfamily
CW753_RS25255	COG0501	Belongs to the peptidase M48B family
CW753_RS25260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CW753_RS25275	COG0191	fructose-bisphosphate aldolase activity
CW753_RS25280	COG0668	transmembrane transport
CW753_RS25290	COG2968	Membrane
CW753_RS25305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CW753_RS25310	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CW753_RS25330	COG0006	proline dipeptidase activity
CW753_RS25335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CW753_RS25340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CW753_RS25360	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS25365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CW753_RS25385	COG2723	6-phospho-beta-galactosidase activity
CW753_RS25390	COG1737	Transcriptional regulator
CW753_RS25400	COG1272	protein, Hemolysin III
CW753_RS25410	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CW753_RS25420	COG0716	FMN binding
CW753_RS25425	COG4974	Belongs to the 'phage' integrase family
CW753_RS25435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CW753_RS25455	COG4942	peptidase
CW753_RS25465	COG0582	viral genome integration into host DNA
CW753_RS25475	COG2801	Transposase and inactivated derivatives
CW753_RS25500	COG1121	(ABC) transporter
CW753_RS25530	COG4983	Phage plasmid primase, P4 family domain protein
CW753_RS25565	COG2003	Belongs to the UPF0758 family
CW753_RS25590	COG2814	Major facilitator Superfamily
CW753_RS25605	COG0667	Aldo Keto reductase
CW753_RS25645	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CW753_RS25650	COG1393	Belongs to the ArsC family
CW753_RS25665	COG1538	Outer membrane efflux protein
CW753_RS25670	COG1289	transmembrane transporter activity
CW753_RS25685	COG3592	Divergent 4Fe-4S mono-cluster
CW753_RS25690	COG2388	GCN5-related N-acetyl-transferase
CW753_RS25700	COG3539	Fimbrial protein
CW753_RS25705	COG3539	Fimbrial protein
CW753_RS25710	COG3539	Fimbrial protein
CW753_RS25715	COG3188	usher protein
CW753_RS25720	COG3121	Chaperone
CW753_RS25725	COG3539	Fimbrial protein
CW753_RS25735	COG4974	Belongs to the 'phage' integrase family
CW753_RS25740	COG0582	viral genome integration into host DNA
CW753_RS25750	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CW753_RS25755	COG1846	Transcriptional regulator
CW753_RS25760	COG0697	spore germination
CW753_RS25810	COG0667	Aldo Keto reductase
CW753_RS25815	COG0814	amino acid
CW753_RS25830	COG0183	Belongs to the thiolase family
CW753_RS25850	COG2814	Major facilitator Superfamily
CW753_RS25880	COG3842	ATPase activity
CW753_RS25885	COG0395	ABC-type sugar transport system, permease component
CW753_RS25890	COG1175	transmembrane transport
CW753_RS25895	COG1917	Cupin 2, conserved barrel domain protein
CW753_RS25900	COG1794	racemase activity, acting on amino acids and derivatives
CW753_RS25905	COG0583	DNA-binding transcription factor activity
CW753_RS25915	COG1609	Transcriptional regulator
CW753_RS25920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CW753_RS25925	COG2723	6-phospho-beta-galactosidase activity
CW753_RS25930	COG2186	Transcriptional regulator
CW753_RS25940	COG1609	Transcriptional regulator
CW753_RS25965	COG0667	Aldo Keto reductase
CW753_RS25975	COG0861	Integral membrane protein TerC family
CW753_RS26005	COG2165	general secretion pathway protein
CW753_RS26010	COG4795	General secretion pathway protein
CW753_RS26020	COG4967	type IV pilus modification protein PilV
CW753_RS26025	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CW753_RS26030	COG1025	Belongs to the peptidase M16 family
CW753_RS26035	COG1074	ATP-dependent DNA helicase activity
CW753_RS26040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CW753_RS26050	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CW753_RS26050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CW753_RS26055	COG0860	N-Acetylmuramoyl-L-alanine amidase
CW753_RS26060	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CW753_RS26090	COG4656	Part of a membrane complex involved in electron transport
CW753_RS26095	COG1012	belongs to the aldehyde dehydrogenase family
CW753_RS26095	COG1454	alcohol dehydrogenase
CW753_RS26125	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CW753_RS26265	COG2801	Transposase and inactivated derivatives
CW753_RS26300	COG5499	transcription regulator containing HTH domain
CW753_RS26360	COG2026	Addiction module toxin, RelE StbE family
CW753_RS26365	COG3077	Addiction module antitoxin, RelB DinJ family
CW753_RS26375	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CW753_RS26405	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CW753_RS26510	COG0583	DNA-binding transcription factor activity
CW753_RS26525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CW753_RS26530	COG0601	transmembrane transport
CW753_RS26540	COG4172	Belongs to the ABC transporter superfamily
CW753_RS26545	COG4948	Mandelate Racemase Muconate Lactonizing
CW753_RS26555	COG1942	4-Oxalocrotonate Tautomerase
CW753_RS26610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CW753_RS26625	COG4372	Transposase
CW753_RS26630	COG3436	PFAM IS66 Orf2 family protein
CW753_RS26660	COG0745	RESPONSE REGULATOR receiver
CW753_RS26665	COG1276	copper resistance
CW753_RS26670	COG2372	response to copper ion
CW753_RS26675	COG3667	copper resistance
CW753_RS26690	COG0739	heme binding
CW753_RS26720	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CW753_RS26765	COG4372	Transposase
CW753_RS26770	COG3436	PFAM IS66 Orf2 family protein
CW753_RS26780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CW753_RS26830	COG2199	diguanylate cyclase activity
CW753_RS26830	COG2203	Gaf domain
CW753_RS26905	COG3344	reverse transcriptase
CW753_RS26975	COG1475	DNA binding
CW753_RS27005	COG2801	Transposase and inactivated derivatives
CW753_RS27080	COG1228	amidohydrolase
CW753_RS27090	COG0402	S-adenosylhomocysteine deaminase activity
CW753_RS27120	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CW753_RS27125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CW753_RS27145	COG3039	Transposase
CW753_RS27225	COG0058	SHG alpha-glucan phosphorylase activity
CW753_RS27295	COG1028	Short-chain dehydrogenase reductase Sdr
CW753_RS27300	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CW753_RS27305	COG1902	pentaerythritol trinitrate reductase activity
CW753_RS27310	COG3118	belongs to the thioredoxin family
CW753_RS27315	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CW753_RS27365	COG3039	Transposase
CW753_RS27375	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CW753_RS27390	COG3039	Transposase
CW753_RS27510	COG3344	reverse transcriptase
CW753_RS27645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CW753_RS27660	COG1192	Involved in chromosome partitioning
CW753_RS27700	COG3039	Transposase
CW753_RS27735	COG0758	DNA mediated transformation
CW753_RS27810	COG0741	lytic transglycosylase activity
CW753_RS27930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CW753_RS27940	COG3436	PFAM IS66 Orf2 family protein
CW753_RS27950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CW753_RS27980	COG3436	PFAM IS66 Orf2 family protein
CW753_RS28020	COG2003	Belongs to the UPF0758 family
CW753_RS28115	COG1192	Involved in chromosome partitioning
CW753_RS28155	COG3039	Transposase
CW753_RS28390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CW753_RS28395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CW753_RS28455	COG3039	Transposase
CW753_RS28475	COG0673	inositol 2-dehydrogenase activity
CW753_RS28515	COG1192	Involved in chromosome partitioning
CW753_RS28555	COG0484	heat shock protein binding