locus-tag	class	description
H1Y02_RS00020	COG0187	DNA topoisomerase II activity
H1Y02_RS00025	COG0561	phosphatase activity
H1Y02_RS00040	COG0823	Involved in the tonB-independent uptake of proteins
H1Y02_RS00045	COG5645	(Lipo)protein
H1Y02_RS00065	COG2188	Transcriptional regulator
H1Y02_RS00080	COG2149	membrane
H1Y02_RS00100	COG2610	gluconate transmembrane transporter activity
H1Y02_RS00105	COG0583	DNA-binding transcription factor activity
H1Y02_RS00110	COG2814	Major facilitator Superfamily
H1Y02_RS00140	COG0028	Belongs to the TPP enzyme family
H1Y02_RS00145	COG0440	acetolactate synthase activity
H1Y02_RS00150	COG2197	response regulator
H1Y02_RS00190	COG2188	Transcriptional regulator
H1Y02_RS00200	COG3842	ATPase activity
H1Y02_RS00220	COG3039	Transposase
H1Y02_RS00225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Y02_RS00225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Y02_RS00240	COG1609	Transcriptional regulator
H1Y02_RS00250	COG3384	dioxygenase
H1Y02_RS00255	COG0583	DNA-binding transcription factor activity
H1Y02_RS00260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H1Y02_RS00265	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1Y02_RS00270	COG2828	Protein conserved in bacteria
H1Y02_RS00285	COG0697	spore germination
H1Y02_RS00290	COG1263	PTS System
H1Y02_RS00290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Y02_RS00300	COG2814	Major facilitator Superfamily
H1Y02_RS00310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Y02_RS00335	COG1309	transcriptional regulator
H1Y02_RS00345	COG0583	DNA-binding transcription factor activity
H1Y02_RS00370	COG1464	Belongs to the NlpA lipoprotein family
H1Y02_RS00385	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H1Y02_RS00395	COG1064	alcohol dehydrogenase
H1Y02_RS00405	COG0604	alcohol dehydrogenase
H1Y02_RS00420	COG2211	Major facilitator Superfamily
H1Y02_RS00425	COG1501	Belongs to the glycosyl hydrolase 31 family
H1Y02_RS00435	COG1486	melibiose metabolic process
H1Y02_RS00440	COG1263	PTS System
H1Y02_RS00440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Y02_RS00445	COG2982	Protein involved in outer membrane biogenesis
H1Y02_RS00450	COG2233	PERMEase
H1Y02_RS00455	COG0786	glutamate:sodium symporter activity
H1Y02_RS00475	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1Y02_RS00500	COG3152	Membrane
H1Y02_RS00510	COG1494	fructose-1,6-bisphosphatase
H1Y02_RS00515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1Y02_RS00520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1Y02_RS00525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1Y02_RS00545	COG2860	membrane
H1Y02_RS00555	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1Y02_RS00555	COG2169	Transcriptional regulator
H1Y02_RS00560	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H1Y02_RS00565	COG1561	YicC-like family, N-terminal region
H1Y02_RS00590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1Y02_RS00625	COG1519	Transferase
H1Y02_RS00630	COG1216	Glycosyl transferase, family 2
H1Y02_RS00635	COG0438	transferase activity, transferring glycosyl groups
H1Y02_RS00645	COG0859	PFAM glycosyl transferase family 9
H1Y02_RS00670	COG0859	PFAM glycosyl transferase family 9
H1Y02_RS00695	COG0463	Glycosyl transferase, family 2
H1Y02_RS00700	COG2861	carbohydrate metabolic process
H1Y02_RS00705	COG4942	peptidase
H1Y02_RS00715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1Y02_RS00720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1Y02_RS00740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1Y02_RS00750	COG2186	Transcriptional regulator
H1Y02_RS00775	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1Y02_RS00780	COG3977	Valine--pyruvate aminotransferase
H1Y02_RS00785	COG0366	Alpha amylase catalytic
H1Y02_RS00790	COG2992	FlgJ-related protein
H1Y02_RS00795	COG1609	Transcriptional regulator
H1Y02_RS00795	COG2207	Transcriptional regulator
H1Y02_RS00800	COG4214	carbohydrate transport
H1Y02_RS00810	COG4213	ABC transporter substrate-binding protein
H1Y02_RS00825	COG4682	membrane
H1Y02_RS00830	COG3274	enterobacterial common antigen metabolic process
H1Y02_RS00860	COG3039	Transposase
H1Y02_RS00875	COG1278	Cold shock
H1Y02_RS00880	COG2944	sequence-specific DNA binding
H1Y02_RS00885	COG2814	Major facilitator Superfamily
H1Y02_RS00905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1Y02_RS00915	COG1609	Transcriptional regulator
H1Y02_RS00920	COG2885	chlorophyll binding
H1Y02_RS00925	COG0243	molybdopterin cofactor binding
H1Y02_RS00930	COG0456	acetyltransferase
H1Y02_RS00935	COG2818	Glycosylase
H1Y02_RS00940	COG5571	outer membrane autotransporter
H1Y02_RS00945	COG2223	nitrite transmembrane transporter activity
H1Y02_RS00975	COG0747	negative chemotaxis
H1Y02_RS00980	COG0601	transmembrane transport
H1Y02_RS00985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Y02_RS00990	COG0444	Belongs to the ABC transporter superfamily
H1Y02_RS00995	COG4608	Belongs to the ABC transporter superfamily
H1Y02_RS01015	COG2894	cell division
H1Y02_RS01025	COG1215	transferase activity, transferring glycosyl groups
H1Y02_RS01030	COG0457	Tetratricopeptide repeat
H1Y02_RS01045	COG2194	sulfuric ester hydrolase activity
H1Y02_RS01075	COG1215	transferase activity, transferring glycosyl groups
H1Y02_RS01080	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H1Y02_RS01085	COG3118	belongs to the thioredoxin family
H1Y02_RS01085	COG0457	Tetratricopeptide repeat
H1Y02_RS01090	COG2200	EAL domain
H1Y02_RS01090	COG2199	diguanylate cyclase activity
H1Y02_RS01100	COG0612	Peptidase, M16
H1Y02_RS01110	COG2982	Protein involved in outer membrane biogenesis
H1Y02_RS01115	COG0477	Major facilitator Superfamily
H1Y02_RS01120	COG1295	ribonuclease BN
H1Y02_RS01125	COG0583	DNA-binding transcription factor activity
H1Y02_RS01130	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS01135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Y02_RS01145	COG1454	alcohol dehydrogenase
H1Y02_RS01155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1Y02_RS01160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1Y02_RS01165	COG0671	phosphoesterase, PA-phosphatase related
H1Y02_RS01295	COG4373	Mu-like prophage FluMu protein gp28
H1Y02_RS01305	COG0640	Transcriptional regulator
H1Y02_RS01320	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
H1Y02_RS01370	COG3409	Peptidoglycan-binding domain 1 protein
H1Y02_RS01370	COG3267	Type II secretory pathway component ExeA
H1Y02_RS01420	COG0589	response to stress
H1Y02_RS01430	COG0306	phosphate transporter
H1Y02_RS01435	COG2081	HI0933 family
H1Y02_RS01440	COG2239	Acts as a magnesium transporter
H1Y02_RS01450	COG1124	(ABC) transporter
H1Y02_RS01460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Y02_RS01465	COG0601	transmembrane transport
H1Y02_RS01470	COG0747	negative chemotaxis
H1Y02_RS01480	COG3479	Phenolic acid decarboxylase
H1Y02_RS01520	COG0628	permease
H1Y02_RS01535	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H1Y02_RS01550	COG3714	YhhN family
H1Y02_RS01560	COG3776	membrane
H1Y02_RS01565	COG0742	ribosomal rna small subunit methyltransferase
H1Y02_RS01570	COG0552	protein localization to endoplasmic reticulum
H1Y02_RS01575	COG2884	Cell division ATP-binding protein ftsE
H1Y02_RS01580	COG2177	Part of the ABC transporter FtsEX involved in
H1Y02_RS01595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1Y02_RS01610	COG0683	leucine binding
H1Y02_RS01615	COG4907	membrane protein (DUF2207)
H1Y02_RS01620	COG1704	LemA family
H1Y02_RS01630	COG0683	leucine binding
H1Y02_RS01635	COG0559	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS01675	COG0584	glycerophosphoryl diester phosphodiesterase
H1Y02_RS01685	COG0405	Gamma-glutamyltransferase
H1Y02_RS01690	COG1247	-acetyltransferase
H1Y02_RS01700	COG0673	inositol 2-dehydrogenase activity
H1Y02_RS01705	COG1741	Belongs to the pirin family
H1Y02_RS01710	COG1609	Transcriptional regulator
H1Y02_RS01715	COG3265	gluconokinase activity
H1Y02_RS01720	COG2610	gluconate transmembrane transporter activity
H1Y02_RS01730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H1Y02_RS01755	COG0058	SHG alpha-glucan phosphorylase activity
H1Y02_RS01760	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H1Y02_RS01775	COG1349	DNA-binding transcription factor activity
H1Y02_RS01785	COG0058	SHG alpha-glucan phosphorylase activity
H1Y02_RS01790	COG1640	4-alpha-glucanotransferase
H1Y02_RS01795	COG2610	gluconate transmembrane transporter activity
H1Y02_RS01805	COG1040	competence protein
H1Y02_RS01830	COG1918	ferrous iron import across plasma membrane
H1Y02_RS01835	COG2183	response to ionizing radiation
H1Y02_RS01840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1Y02_RS01845	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS01865	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1Y02_RS01870	COG1011	Hydrolase
H1Y02_RS01880	COG0494	nUDIX hydrolase
H1Y02_RS01885	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H1Y02_RS01890	COG4972	Pilus assembly protein
H1Y02_RS01910	COG4796	Type ii and iii secretion system protein
H1Y02_RS01925	COG3266	domain, Protein
H1Y02_RS01930	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H1Y02_RS01935	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1Y02_RS01960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1Y02_RS01965	COG0402	S-adenosylhomocysteine deaminase activity
H1Y02_RS01970	COG0738	Major facilitator superfamily
H1Y02_RS01995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1Y02_RS02000	COG1289	transmembrane transporter activity
H1Y02_RS02010	COG1765	OsmC-like protein
H1Y02_RS02015	COG3954	Phosphoribulokinase
H1Y02_RS02025	COG0429	hydrolase of the alpha beta-hydrolase fold
H1Y02_RS02030	COG0488	(ABC) transporter
H1Y02_RS02045	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H1Y02_RS02050	COG1047	Peptidyl-prolyl cis-trans
H1Y02_RS02060	COG0545	Peptidyl-prolyl cis-trans isomerase
H1Y02_RS02065	COG2964	Protein conserved in bacteria
H1Y02_RS02120	COG0051	transcription antitermination factor activity, RNA binding
H1Y02_RS02145	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H1Y02_RS02160	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H1Y02_RS02225	COG0201	protein transport
H1Y02_RS02250	COG0202	RNA polymerase activity
H1Y02_RS02265	COG0789	Transcriptional regulator
H1Y02_RS02270	COG3036	rescue of stalled ribosome
H1Y02_RS02300	COG0758	DNA mediated transformation
H1Y02_RS02310	COG0551	DNA topoisomerase type I activity
H1Y02_RS02330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1Y02_RS02365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Y02_RS02370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Y02_RS02375	COG1309	transcriptional regulator
H1Y02_RS02395	COG3561	AntA/AntB antirepressor
H1Y02_RS02480	COG2005	Transcriptional regulator
H1Y02_RS02480	COG3585	molybdate ion transport
H1Y02_RS02500	COG4145	pantothenate transmembrane transporter activity
H1Y02_RS02505	COG3924	membrane
H1Y02_RS02510	COG0439	Biotin carboxylase
H1Y02_RS02515	COG0511	ligase activity, forming carbon-carbon bonds
H1Y02_RS02540	COG2199	diguanylate cyclase activity
H1Y02_RS02540	COG2200	EAL domain
H1Y02_RS02545	COG1077	Cell shape determining protein MreB Mrl
H1Y02_RS02550	COG1792	Involved in formation and maintenance of cell shape
H1Y02_RS02555	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1Y02_RS02565	COG1530	ribonuclease E activity
H1Y02_RS02570	COG3164	Protein of unknown function
H1Y02_RS02575	COG0312	modulator of DNA gyrase
H1Y02_RS02580	COG0583	DNA-binding transcription factor activity
H1Y02_RS02595	COG1289	transmembrane transporter activity
H1Y02_RS02600	COG2732	(Barnase) inhibitor
H1Y02_RS02625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1Y02_RS02630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1Y02_RS02635	COG3105	Protein conserved in bacteria
H1Y02_RS02640	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1Y02_RS02660	COG0625	glutathione transferase activity
H1Y02_RS02665	COG2969	positive regulation of protein catabolic process
H1Y02_RS02695	COG2731	YhcH YjgK YiaL family protein
H1Y02_RS02700	COG0493	'glutamate synthase
H1Y02_RS02705	COG0067	glutamate synthase
H1Y02_RS02705	COG0070	glutamate synthase
H1Y02_RS02705	COG0069	glutamate synthase activity
H1Y02_RS02710	COG1242	4 iron, 4 sulfur cluster binding
H1Y02_RS02715	COG2271	Major facilitator Superfamily
H1Y02_RS02720	COG1063	alcohol dehydrogenase
H1Y02_RS02725	COG1312	Catalyzes the dehydration of D-mannonate
H1Y02_RS02730	COG0784	Response regulator, receiver
H1Y02_RS02730	COG2198	Histidine kinase
H1Y02_RS02730	COG5002	protein histidine kinase activity
H1Y02_RS02735	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H1Y02_RS02740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1Y02_RS02745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS02755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS02760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H1Y02_RS02765	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H1Y02_RS02770	COG1137	ATPase activity
H1Y02_RS02775	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H1Y02_RS02780	COG3117	lipopolysaccharide transmembrane transporter activity
H1Y02_RS02785	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H1Y02_RS02795	COG0530	calcium, potassium:sodium antiporter activity
H1Y02_RS02800	COG1127	ABC transporter
H1Y02_RS02805	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1Y02_RS02810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1Y02_RS02815	COG2854	intermembrane phospholipid transfer
H1Y02_RS02820	COG3113	response to antibiotic
H1Y02_RS02825	COG5007	Belongs to the BolA IbaG family
H1Y02_RS02835	COG3423	Transcriptional regulator
H1Y02_RS02840	COG0142	geranyltranstransferase activity
H1Y02_RS02855	COG0697	spore germination
H1Y02_RS02865	COG2027	D-alanyl-D-alanine carboxypeptidase
H1Y02_RS02875	COG1534	Rna-binding protein
H1Y02_RS02885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1Y02_RS02890	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1Y02_RS02900	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H1Y02_RS02940	COG0195	Participates in both transcription termination and antitermination
H1Y02_RS02985	COG0814	amino acid
H1Y02_RS02990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Y02_RS02995	COG0826	peptidase U32
H1Y02_RS03000	COG0826	peptidase U32
H1Y02_RS03005	COG3154	lipid carrier protein
H1Y02_RS03010	COG3153	acetyltransferase
H1Y02_RS03025	COG0693	protein deglycase activity
H1Y02_RS03030	COG0702	epimerase
H1Y02_RS03035	COG0701	Predicted permease
H1Y02_RS03040	COG2823	Periplasmic or secreted lipoprotein
H1Y02_RS03060	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H1Y02_RS03065	COG2721	sulfolactate sulfo-lyase activity
H1Y02_RS03075	COG2084	Dehydrogenase
H1Y02_RS03105	COG1741	Belongs to the pirin family
H1Y02_RS03110	COG0583	DNA-binding transcription factor activity
H1Y02_RS03115	COG3152	Membrane
H1Y02_RS03120	COG0435	Glutathione S-transferase
H1Y02_RS03125	COG2259	Doxx family
H1Y02_RS03135	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
H1Y02_RS03140	COG4575	ribosome binding
H1Y02_RS03145	COG1422	Protein of unknown function (DUF1090)
H1Y02_RS03155	COG0586	Pfam SNARE associated Golgi protein
H1Y02_RS03160	COG2186	Transcriptional regulator
H1Y02_RS03165	COG2271	Major facilitator Superfamily
H1Y02_RS03175	COG2721	sulfolactate sulfo-lyase activity
H1Y02_RS03190	COG0861	Integral membrane protein TerC family
H1Y02_RS03195	COG0673	inositol 2-dehydrogenase activity
H1Y02_RS03200	COG1451	nucleotide metabolic process
H1Y02_RS03220	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1Y02_RS03220	COG1902	pentaerythritol trinitrate reductase activity
H1Y02_RS03270	COG1695	Transcriptional regulator
H1Y02_RS03275	COG2375	cellular response to nickel ion
H1Y02_RS03290	COG1461	Dihydroxyacetone kinase
H1Y02_RS03295	COG2376	Dihydroxyacetone kinase
H1Y02_RS03320	COG3039	Transposase
H1Y02_RS03325	COG3247	response to pH
H1Y02_RS03335	COG2205	protein histidine kinase activity
H1Y02_RS03335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Y02_RS03335	COG2198	Histidine kinase
H1Y02_RS03335	COG0784	Response regulator, receiver
H1Y02_RS03340	COG2197	response regulator
H1Y02_RS03355	COG3039	Transposase
H1Y02_RS03455	COG4626	Terminase
H1Y02_RS03455	COG1802	Transcriptional regulator
H1Y02_RS03475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H1Y02_RS03480	COG0358	DNA primase activity
H1Y02_RS03485	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H1Y02_RS03550	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H1Y02_RS03565	COG4991	sh3 domain protein
H1Y02_RS03570	COG3025	triphosphatase activity
H1Y02_RS03595	COG2960	long-chain fatty acid transporting porin activity
H1Y02_RS03610	COG3384	dioxygenase
H1Y02_RS03615	COG0754	glutathionylspermidine amidase activity
H1Y02_RS03625	COG1538	Outer membrane efflux protein
H1Y02_RS03630	COG0494	nUDIX hydrolase
H1Y02_RS03635	COG3151	Protein conserved in bacteria
H1Y02_RS03640	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1Y02_RS03645	COG3150	esterase
H1Y02_RS03655	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1Y02_RS03660	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1Y02_RS03665	COG0642	Histidine kinase
H1Y02_RS03675	COG3111	PFAM Bacterial OB fold (BOF) protein
H1Y02_RS03680	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1Y02_RS03690	COG0204	Acyl-transferase
H1Y02_RS03695	COG2132	Multicopper oxidase
H1Y02_RS03700	COG1032	radical SAM domain protein
H1Y02_RS03705	COG0656	L-ascorbic acid biosynthetic process
H1Y02_RS03710	COG1979	alcohol dehydrogenase
H1Y02_RS03715	COG2207	Transcriptional regulator
H1Y02_RS03720	COG0586	Pfam SNARE associated Golgi protein
H1Y02_RS03735	COG0848	biopolymer transport protein
H1Y02_RS03755	COG0625	glutathione transferase activity
H1Y02_RS03770	COG0754	glutathionylspermidine amidase activity
H1Y02_RS03775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Y02_RS03795	COG0583	DNA-binding transcription factor activity
H1Y02_RS03800	COG0626	cystathionine gamma-synthase activity
H1Y02_RS03815	COG1811	Na channel or pump
H1Y02_RS03820	COG1982	Orn Lys Arg decarboxylase major
H1Y02_RS03825	COG2211	Major facilitator Superfamily
H1Y02_RS03840	COG1194	a g-specific adenine glycosylase
H1Y02_RS03850	COG3171	Protein conserved in bacteria
H1Y02_RS03865	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H1Y02_RS03870	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Y02_RS03875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1Y02_RS03890	COG0762	integral membrane protein
H1Y02_RS03895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H1Y02_RS03900	COG2805	Type II/IV secretion system protein
H1Y02_RS03920	COG0189	ligase activity
H1Y02_RS03925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1Y02_RS03930	COG2356	endonuclease I
H1Y02_RS03940	COG2814	Major facilitator Superfamily
H1Y02_RS03975	COG2146	nitrite reductase [NAD(P)H] activity
H1Y02_RS03990	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS03995	COG1414	Transcriptional regulator
H1Y02_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS04030	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
H1Y02_RS04050	COG0501	Belongs to the peptidase M48B family
H1Y02_RS04055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1Y02_RS04070	COG0191	fructose-bisphosphate aldolase activity
H1Y02_RS04075	COG0668	transmembrane transport
H1Y02_RS04085	COG2968	Membrane
H1Y02_RS04100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1Y02_RS04105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1Y02_RS04125	COG0006	proline dipeptidase activity
H1Y02_RS04130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1Y02_RS04135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1Y02_RS04155	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS04160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1Y02_RS04180	COG2723	6-phospho-beta-galactosidase activity
H1Y02_RS04185	COG1737	Transcriptional regulator
H1Y02_RS04195	COG1272	protein, Hemolysin III
H1Y02_RS04205	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H1Y02_RS04215	COG0716	FMN binding
H1Y02_RS04220	COG4974	Belongs to the 'phage' integrase family
H1Y02_RS04230	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1Y02_RS04250	COG4942	peptidase
H1Y02_RS04260	COG2814	Major facilitator Superfamily
H1Y02_RS04275	COG0667	Aldo Keto reductase
H1Y02_RS04315	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H1Y02_RS04320	COG1393	Belongs to the ArsC family
H1Y02_RS04325	COG3104	oligopeptide transport
H1Y02_RS04335	COG1538	Outer membrane efflux protein
H1Y02_RS04340	COG1289	transmembrane transporter activity
H1Y02_RS04355	COG3592	Divergent 4Fe-4S mono-cluster
H1Y02_RS04360	COG2388	GCN5-related N-acetyl-transferase
H1Y02_RS04370	COG3539	Fimbrial protein
H1Y02_RS04375	COG3539	Fimbrial protein
H1Y02_RS04380	COG3539	Fimbrial protein
H1Y02_RS04385	COG3188	usher protein
H1Y02_RS04390	COG3121	Chaperone
H1Y02_RS04395	COG3539	Fimbrial protein
H1Y02_RS04405	COG4974	Belongs to the 'phage' integrase family
H1Y02_RS04410	COG0582	viral genome integration into host DNA
H1Y02_RS04425	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
H1Y02_RS04430	COG1846	Transcriptional regulator
H1Y02_RS04435	COG0697	spore germination
H1Y02_RS04485	COG0667	Aldo Keto reductase
H1Y02_RS04490	COG0814	amino acid
H1Y02_RS04505	COG0183	Belongs to the thiolase family
H1Y02_RS04515	COG0823	Involved in the tonB-independent uptake of proteins
H1Y02_RS04520	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS04525	COG2814	Major facilitator Superfamily
H1Y02_RS04560	COG3842	ATPase activity
H1Y02_RS04565	COG0395	ABC-type sugar transport system, permease component
H1Y02_RS04570	COG1175	transmembrane transport
H1Y02_RS04575	COG1917	Cupin 2, conserved barrel domain protein
H1Y02_RS04580	COG1794	racemase activity, acting on amino acids and derivatives
H1Y02_RS04585	COG0583	DNA-binding transcription factor activity
H1Y02_RS04595	COG1609	Transcriptional regulator
H1Y02_RS04600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Y02_RS04605	COG2723	6-phospho-beta-galactosidase activity
H1Y02_RS04610	COG2186	Transcriptional regulator
H1Y02_RS04620	COG1609	Transcriptional regulator
H1Y02_RS04635	COG0667	Aldo Keto reductase
H1Y02_RS04645	COG0861	Integral membrane protein TerC family
H1Y02_RS04680	COG2165	general secretion pathway protein
H1Y02_RS04685	COG4795	General secretion pathway protein
H1Y02_RS04695	COG4967	type IV pilus modification protein PilV
H1Y02_RS04700	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H1Y02_RS04705	COG1025	Belongs to the peptidase M16 family
H1Y02_RS04710	COG1074	ATP-dependent DNA helicase activity
H1Y02_RS04715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1Y02_RS04725	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H1Y02_RS04725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H1Y02_RS04730	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1Y02_RS04735	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H1Y02_RS04765	COG4656	Part of a membrane complex involved in electron transport
H1Y02_RS04770	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS04770	COG1454	alcohol dehydrogenase
H1Y02_RS04800	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
H1Y02_RS04965	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H1Y02_RS04970	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1Y02_RS04975	COG2166	iron-sulfur cluster assembly
H1Y02_RS04980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1Y02_RS04990	COG0583	DNA-binding transcription factor activity
H1Y02_RS04995	COG2363	Small membrane protein
H1Y02_RS05005	COG1349	DNA-binding transcription factor activity
H1Y02_RS05025	COG0738	Major facilitator superfamily
H1Y02_RS05030	COG0235	Class ii aldolase
H1Y02_RS05035	COG1454	alcohol dehydrogenase
H1Y02_RS05050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Y02_RS05065	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1Y02_RS05070	COG2011	ABC-type metal ion transport system permease component
H1Y02_RS05075	COG1464	Belongs to the NlpA lipoprotein family
H1Y02_RS05080	COG0477	Major facilitator Superfamily
H1Y02_RS05090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1Y02_RS05095	COG1760	l-serine dehydratase
H1Y02_RS05100	COG0814	amino acid
H1Y02_RS05105	COG1611	Belongs to the LOG family
H1Y02_RS05130	COG2271	Major facilitator Superfamily
H1Y02_RS05135	COG4948	Mandelate Racemase Muconate Lactonizing
H1Y02_RS05140	COG4948	Mandelate Racemase Muconate Lactonizing
H1Y02_RS05145	COG1929	Belongs to the glycerate kinase type-1 family
H1Y02_RS05150	COG4999	Histidine kinase
H1Y02_RS05150	COG3850	Histidine kinase
H1Y02_RS05150	COG3437	response regulator, receiver
H1Y02_RS05150	COG2205	protein histidine kinase activity
H1Y02_RS05160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1Y02_RS05165	COG3956	TIGRFAM MazG family protein
H1Y02_RS05185	COG0602	queuosine metabolic process
H1Y02_RS05190	COG0720	synthase
H1Y02_RS05210	COG2234	aminopeptidase activity
H1Y02_RS05270	COG1388	LysM domain
H1Y02_RS05270	COG4942	peptidase
H1Y02_RS05275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H1Y02_RS05300	COG0163	prenyltransferase activity
H1Y02_RS05305	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H1Y02_RS05340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Y02_RS05345	COG4558	Periplasmic binding protein
H1Y02_RS05350	COG3720	iron ion transport
H1Y02_RS05370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1Y02_RS05375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1Y02_RS05380	COG1121	(ABC) transporter
H1Y02_RS05390	COG1609	Transcriptional regulator
H1Y02_RS05395	COG1940	carbohydrate kinase activity
H1Y02_RS05400	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1Y02_RS05405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Y02_RS05410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Y02_RS05415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Y02_RS05420	COG4580	involved in the transport of maltose and maltodextrins
H1Y02_RS05430	COG2723	6-phospho-beta-galactosidase activity
H1Y02_RS05440	COG0309	Hydrogenase expression formation protein (HypE)
H1Y02_RS05445	COG0409	Hydrogenase expression formation protein
H1Y02_RS05450	COG0298	carbon dioxide binding
H1Y02_RS05455	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H1Y02_RS05470	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1Y02_RS05475	COG0651	ATP synthesis coupled electron transport
H1Y02_RS05480	COG0650	Formate hydrogenlyase subunit 4
H1Y02_RS05485	COG3261	NADH dehydrogenase
H1Y02_RS05485	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
H1Y02_RS05490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1Y02_RS05495	COG3260	NADH ubiquinone oxidoreductase 20
H1Y02_RS05505	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H1Y02_RS05515	COG2723	6-phospho-beta-galactosidase activity
H1Y02_RS05520	COG1263	PTS System
H1Y02_RS05520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Y02_RS05525	COG1609	Transcriptional regulator
H1Y02_RS05530	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1Y02_RS05535	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
H1Y02_RS05540	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
H1Y02_RS05550	COG1414	Transcriptional regulator
H1Y02_RS05555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1Y02_RS05560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1Y02_RS05585	COG1349	DNA-binding transcription factor activity
H1Y02_RS05590	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS05595	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS05605	COG3732	PTS system glucitol sorbitol-specific
H1Y02_RS05610	COG3730	PTS system glucitol sorbitol-specific
H1Y02_RS05615	COG2951	lytic endotransglycosylase activity
H1Y02_RS05620	COG1121	(ABC) transporter
H1Y02_RS05625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1Y02_RS05630	COG0803	Belongs to the bacterial solute-binding protein 9 family
H1Y02_RS05635	COG1546	Belongs to the CinA family
H1Y02_RS05655	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H1Y02_RS05685	COG2823	Periplasmic or secreted lipoprotein
H1Y02_RS05690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1Y02_RS05695	COG1238	metal cluster binding
H1Y02_RS05715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1Y02_RS05720	COG2814	Major facilitator Superfamily
H1Y02_RS05725	COG1566	PFAM secretion protein HlyD family protein
H1Y02_RS05730	COG1846	Transcriptional regulator
H1Y02_RS05740	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1Y02_RS05750	COG4176	ABC-type proline glycine betaine transport system permease component
H1Y02_RS05765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1Y02_RS05775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1Y02_RS05780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1Y02_RS05790	COG4575	ribosome binding
H1Y02_RS05820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1Y02_RS05825	COG0640	Transcriptional regulator
H1Y02_RS05835	COG0583	DNA-binding transcription factor activity
H1Y02_RS05840	COG0671	phosphoesterase, PA-phosphatase related
H1Y02_RS05845	COG3284	Transcriptional regulator
H1Y02_RS05850	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS05855	COG3539	Fimbrial protein
H1Y02_RS05860	COG3039	Transposase
H1Y02_RS05915	COG0582	viral genome integration into host DNA
H1Y02_RS05930	COG2867	negative regulation of translational initiation
H1Y02_RS05945	COG0497	DNA recombination
H1Y02_RS05960	COG4536	flavin adenine dinucleotide binding
H1Y02_RS05965	COG4137	Cytochrome C assembly protein
H1Y02_RS05970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1Y02_RS06005	COG2885	chlorophyll binding
H1Y02_RS06010	COG2199	diguanylate cyclase activity
H1Y02_RS06020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1Y02_RS06025	COG0287	Prephenate dehydrogenase
H1Y02_RS06025	COG1605	Chorismate mutase
H1Y02_RS06035	COG1605	Chorismate mutase
H1Y02_RS06035	COG0077	Prephenate dehydratase
H1Y02_RS06045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H1Y02_RS06050	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1Y02_RS06065	COG0542	response to heat
H1Y02_RS06095	COG0477	Major facilitator Superfamily
H1Y02_RS06100	COG5544	Lipoprotein
H1Y02_RS06105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1Y02_RS06120	COG3118	belongs to the thioredoxin family
H1Y02_RS06125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1Y02_RS06140	COG0513	Belongs to the DEAD box helicase family
H1Y02_RS06150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H1Y02_RS06165	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
H1Y02_RS06170	COG3026	antisigma factor binding
H1Y02_RS06175	COG3086	response to oxidative stress
H1Y02_RS06185	COG0681	Belongs to the peptidase S26 family
H1Y02_RS06205	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1Y02_RS06215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1Y02_RS06220	COG1737	Transcriptional regulator
H1Y02_RS06225	COG0560	Phosphoserine phosphatase
H1Y02_RS06240	COG0047	phosphoribosylformylglycinamidine synthase activity
H1Y02_RS06240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1Y02_RS06245	COG2205	protein histidine kinase activity
H1Y02_RS06250	COG3170	Tfp pilus assembly protein FimV
H1Y02_RS06255	COG2204	response regulator
H1Y02_RS06260	COG0347	Belongs to the P(II) protein family
H1Y02_RS06265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1Y02_RS06265	COG1017	nitric oxide dioxygenase activity
H1Y02_RS06275	COG2259	Doxx family
H1Y02_RS06280	COG2814	Major facilitator Superfamily
H1Y02_RS06285	COG3711	transcriptional antiterminator
H1Y02_RS06290	COG3683	transport system, periplasmic component
H1Y02_RS06295	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
H1Y02_RS06325	COG0822	iron-sulfur transferase activity
H1Y02_RS06345	COG0633	Ferredoxin
H1Y02_RS06350	COG2975	iron-sulfur cluster assembly
H1Y02_RS06375	COG2897	thiosulfate sulfurtransferase activity
H1Y02_RS06380	COG2373	Large extracellular alpha-helical protein
H1Y02_RS06385	COG4953	penicillin-binding protein 1C
H1Y02_RS06415	COG2976	Protein conserved in bacteria
H1Y02_RS06435	COG1645	bacterial-type flagellum-dependent swarming motility
H1Y02_RS06445	COG0516	GMP reductase activity
H1Y02_RS06445	COG0517	IMP dehydrogenase activity
H1Y02_RS06470	COG2200	EAL domain
H1Y02_RS06485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1Y02_RS06500	COG2723	6-phospho-beta-galactosidase activity
H1Y02_RS06510	COG2233	PERMEase
H1Y02_RS06525	COG1393	Belongs to the ArsC family
H1Y02_RS06530	COG4783	chaperone-mediated protein folding
H1Y02_RS06540	COG0628	permease
H1Y02_RS06545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1Y02_RS06550	COG2716	regulation of RNA biosynthetic process
H1Y02_RS06560	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H1Y02_RS06570	COG2321	neutral zinc metallopeptidase
H1Y02_RS06575	COG1444	tRNA N-acetyltransferase activity
H1Y02_RS06580	COG0400	carboxylic ester hydrolase activity
H1Y02_RS06595	COG1393	Belongs to the ArsC family
H1Y02_RS06605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Y02_RS06620	COG5342	invasion associated locus B
H1Y02_RS06625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1Y02_RS06630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1Y02_RS06645	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1Y02_RS06665	COG2837	iron assimilation
H1Y02_RS06670	COG2852	Protein conserved in bacteria
H1Y02_RS06675	COG4150	thiosulfate binding
H1Y02_RS06680	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1Y02_RS06685	COG4208	sulfate ABC transporter
H1Y02_RS06690	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H1Y02_RS06700	COG4319	ketosteroid isomerase
H1Y02_RS06735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1Y02_RS06755	COG3530	Putative quorum-sensing-regulated virulence factor
H1Y02_RS06760	COG0385	Bile acid
H1Y02_RS06765	COG0583	DNA-binding transcription factor activity
H1Y02_RS06800	COG3415	Transposase
H1Y02_RS06805	COG3415	Transposase
H1Y02_RS06820	COG2200	EAL domain
H1Y02_RS06820	COG2199	diguanylate cyclase activity
H1Y02_RS06825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H1Y02_RS06840	COG0667	Aldo Keto reductase
H1Y02_RS06845	COG3961	Belongs to the TPP enzyme family
H1Y02_RS06860	COG3279	Response regulator of the LytR AlgR family
H1Y02_RS06865	COG3275	phosphorelay sensor kinase activity
H1Y02_RS06875	COG0436	Aminotransferase
H1Y02_RS06885	COG2807	transmembrane transport
H1Y02_RS06890	COG0590	tRNA wobble adenosine to inosine editing
H1Y02_RS06895	COG0583	DNA-binding transcription factor activity
H1Y02_RS06910	COG3706	GGDEF domain
H1Y02_RS06920	COG0582	viral genome integration into host DNA
H1Y02_RS06990	COG3039	Transposase
H1Y02_RS07000	COG3344	reverse transcriptase
H1Y02_RS07010	COG2116	formate transmembrane transporter activity
H1Y02_RS07015	COG2853	Lipoprotein
H1Y02_RS07025	COG3039	Transposase
H1Y02_RS07035	COG3691	Protein conserved in bacteria
H1Y02_RS07050	COG2062	phosphohistidine phosphatase, SixA
H1Y02_RS07075	COG0730	response to heat
H1Y02_RS07080	COG3101	peptidyl-lysine hydroxylation
H1Y02_RS07095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1Y02_RS07115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H1Y02_RS07125	COG0586	Pfam SNARE associated Golgi protein
H1Y02_RS07135	COG0285	dihydrofolate synthase activity
H1Y02_RS07140	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
H1Y02_RS07145	COG1286	toxin biosynthetic process
H1Y02_RS07150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H1Y02_RS07155	COG0163	prenyltransferase activity
H1Y02_RS07180	COG4160	amino acid transport
H1Y02_RS07185	COG4598	ABC transporter
H1Y02_RS07200	COG1090	epimerase
H1Y02_RS07205	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H1Y02_RS07210	COG0625	glutathione transferase activity
H1Y02_RS07215	COG0625	glutathione transferase activity
H1Y02_RS07220	COG0622	Phosphoesterase
H1Y02_RS07225	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H1Y02_RS07250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1Y02_RS07255	COG0490	domain, Protein
H1Y02_RS07255	COG0471	metal ion transport
H1Y02_RS07265	COG0436	Aminotransferase
H1Y02_RS07270	COG3039	Transposase
H1Y02_RS07275	COG0583	DNA-binding transcription factor activity
H1Y02_RS07320	COG0839	Belongs to the complex I subunit 6 family
H1Y02_RS07330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1Y02_RS07335	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1Y02_RS07350	COG2153	protein acetylation
H1Y02_RS07355	COG1169	isochorismate synthase
H1Y02_RS07405	COG0642	Histidine kinase
H1Y02_RS07425	COG1414	Transcriptional regulator
H1Y02_RS07435	COG2271	Major facilitator Superfamily
H1Y02_RS07445	COG0247	lactate metabolic process
H1Y02_RS07455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H1Y02_RS07460	COG2271	Major facilitator Superfamily
H1Y02_RS07465	COG0584	glycerophosphoryl diester phosphodiesterase
H1Y02_RS07470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1Y02_RS07505	COG2198	Histidine kinase
H1Y02_RS07505	COG0642	Histidine kinase
H1Y02_RS07520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1Y02_RS07520	COG2169	Transcriptional regulator
H1Y02_RS07525	COG3145	DNA-N1-methyladenine dioxygenase activity
H1Y02_RS07530	COG4615	Cyclic peptide transporter
H1Y02_RS07535	COG2239	Acts as a magnesium transporter
H1Y02_RS07540	COG0659	secondary active sulfate transmembrane transporter activity
H1Y02_RS07560	COG0628	permease
H1Y02_RS07585	COG1349	DNA-binding transcription factor activity
H1Y02_RS07590	COG0494	nUDIX hydrolase
H1Y02_RS07610	COG1061	Type III restriction enzyme res subunit
H1Y02_RS07615	COG1187	pseudouridine synthase activity
H1Y02_RS07620	COG2814	Major facilitator Superfamily
H1Y02_RS07630	COG4172	Belongs to the ABC transporter superfamily
H1Y02_RS07635	COG4239	(ABC) transporter, permease
H1Y02_RS07640	COG4174	ABC transporter (Permease)
H1Y02_RS07645	COG4166	transmembrane transport
H1Y02_RS07650	COG2200	EAL domain
H1Y02_RS07655	COG0791	NLP P60 protein
H1Y02_RS07660	COG0671	phosphoesterase, PA-phosphatase related
H1Y02_RS07665	COG0523	cobalamin synthesis protein
H1Y02_RS07670	COG0246	Mannitol dehydrogenase
H1Y02_RS07675	COG1312	Catalyzes the dehydration of D-mannonate
H1Y02_RS07700	COG1566	PFAM secretion protein HlyD family protein
H1Y02_RS07705	COG2814	Major facilitator Superfamily
H1Y02_RS07710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS07710	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS07715	COG1105	Belongs to the carbohydrate kinase PfkB family
H1Y02_RS07720	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H1Y02_RS07720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1Y02_RS07720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1Y02_RS07730	COG2855	membrane
H1Y02_RS07735	COG0583	DNA-binding transcription factor activity
H1Y02_RS07740	COG0833	amino acid
H1Y02_RS07745	COG4771	TonB-dependent receptor
H1Y02_RS07760	COG2311	Membrane
H1Y02_RS07785	COG1129	ABC transporter
H1Y02_RS07795	COG2949	membrane
H1Y02_RS07805	COG1346	cytolysis
H1Y02_RS07815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1Y02_RS07820	COG3659	wide pore channel activity
H1Y02_RS07835	COG2723	6-phospho-beta-galactosidase activity
H1Y02_RS07840	COG2226	methyltransferase
H1Y02_RS07845	COG1538	Outer membrane efflux protein
H1Y02_RS07850	COG0586	Pfam SNARE associated Golgi protein
H1Y02_RS07860	COG1686	Belongs to the peptidase S11 family
H1Y02_RS07870	COG0277	FAD linked oxidase domain protein
H1Y02_RS07875	COG1472	Belongs to the glycosyl hydrolase 3 family
H1Y02_RS07880	COG1732	Glycine betaine
H1Y02_RS07885	COG1174	glycine betaine transport
H1Y02_RS07890	COG1125	glycine betaine transport
H1Y02_RS07895	COG1174	glycine betaine transport
H1Y02_RS07905	COG3275	phosphorelay sensor kinase activity
H1Y02_RS07915	COG4807	Protein conserved in bacteria
H1Y02_RS07935	COG5455	response to cobalt ion
H1Y02_RS07940	COG0583	DNA-binding transcription factor activity
H1Y02_RS07945	COG2252	PERMEase
H1Y02_RS07955	COG0583	DNA-binding transcription factor activity
H1Y02_RS07970	COG0351	phosphomethylpyrimidine kinase
H1Y02_RS07975	COG1830	Aldolase
H1Y02_RS08000	COG2390	Transcriptional regulator
H1Y02_RS08010	COG1070	Carbohydrate kinase
H1Y02_RS08020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1Y02_RS08025	COG4948	Mandelate Racemase Muconate Lactonizing
H1Y02_RS08030	COG0747	negative chemotaxis
H1Y02_RS08035	COG0601	transmembrane transport
H1Y02_RS08045	COG0444	Belongs to the ABC transporter superfamily
H1Y02_RS08050	COG4608	Belongs to the ABC transporter superfamily
H1Y02_RS08065	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS08070	COG2205	protein histidine kinase activity
H1Y02_RS08095	COG1301	dicarboxylic acid transport
H1Y02_RS08115	COG2205	protein histidine kinase activity
H1Y02_RS08120	COG0443	Heat shock 70 kDa protein
H1Y02_RS08125	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H1Y02_RS08140	COG2982	Protein involved in outer membrane biogenesis
H1Y02_RS08145	COG1253	flavin adenine dinucleotide binding
H1Y02_RS08175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1Y02_RS08190	COG0463	Glycosyl transferase, family 2
H1Y02_RS08270	COG1088	dTDP-glucose 4,6-dehydratase activity
H1Y02_RS08325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1Y02_RS08355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Y02_RS08360	COG0583	DNA-binding transcription factor activity
H1Y02_RS08370	COG0531	amino acid
H1Y02_RS08375	COG0640	Transcriptional regulator
H1Y02_RS08380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H1Y02_RS08385	COG2925	Exonuclease
H1Y02_RS08400	COG1289	transmembrane transporter activity
H1Y02_RS08420	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H1Y02_RS08430	COG1942	4-Oxalocrotonate Tautomerase
H1Y02_RS08435	COG0583	DNA-binding transcription factor activity
H1Y02_RS08440	COG0095	Lipoate-protein ligase
H1Y02_RS08445	COG0477	Major facilitator Superfamily
H1Y02_RS08455	COG3300	MHYT domain
H1Y02_RS08455	COG5001	Diguanylate cyclase
H1Y02_RS08460	COG3615	Tellurite resistance protein tehB
H1Y02_RS08485	COG3706	GGDEF domain
H1Y02_RS08500	COG0534	Mate efflux family protein
H1Y02_RS08570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1Y02_RS08590	COG0604	alcohol dehydrogenase
H1Y02_RS08595	COG1309	transcriptional regulator
H1Y02_RS08600	COG0025	NhaP-type Na H and K H
H1Y02_RS08620	COG1376	ErfK ybiS ycfS ynhG family protein
H1Y02_RS08640	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H1Y02_RS08660	COG1418	mRNA catabolic process
H1Y02_RS08665	COG0270	DNA (cytosine-5-)-methyltransferase activity
H1Y02_RS08670	COG3727	T/G mismatch-specific endonuclease activity
H1Y02_RS08675	COG0697	spore germination
H1Y02_RS08680	COG2354	Protein conserved in bacteria
H1Y02_RS08710	COG0366	Alpha amylase catalytic
H1Y02_RS08735	COG2197	response regulator
H1Y02_RS08745	COG3039	Transposase
H1Y02_RS08750	COG2197	response regulator
H1Y02_RS08790	COG3318	Belongs to the UPF0149 family
H1Y02_RS08790	COG3012	SEC-C Motif Domain Protein
H1Y02_RS08795	COG0814	amino acid
H1Y02_RS08805	COG1528	Iron-storage protein
H1Y02_RS08815	COG0477	Major facilitator Superfamily
H1Y02_RS08825	COG2211	Major facilitator Superfamily
H1Y02_RS08825	COG2211	Major facilitator Superfamily
H1Y02_RS08835	COG1528	Iron-storage protein
H1Y02_RS08840	COG1879	ABC-type sugar transport system periplasmic component
H1Y02_RS08850	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS08875	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H1Y02_RS08885	COG3102	Protein conserved in bacteria
H1Y02_RS08905	COG3788	relative of glutathione S-transferase, MAPEG superfamily
H1Y02_RS08910	COG1801	Protein of unknown function DUF72
H1Y02_RS08915	COG1335	isochorismatase
H1Y02_RS08925	COG0494	nUDIX hydrolase
H1Y02_RS08950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1Y02_RS08960	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
H1Y02_RS08965	COG0739	heme binding
H1Y02_RS08970	COG1560	Kdo2-lipid A biosynthetic process
H1Y02_RS08985	COG3039	Transposase
H1Y02_RS08990	COG3039	Transposase
H1Y02_RS09000	COG3493	citrate carrier protein
H1Y02_RS09010	COG1737	Transcriptional regulator
H1Y02_RS09020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H1Y02_RS09025	COG0129	dihydroxy-acid dehydratase activity
H1Y02_RS09030	COG0800	Aldolase
H1Y02_RS09040	COG3141	response to X-ray
H1Y02_RS09045	COG2979	Protein of unknown function (DUF533)
H1Y02_RS09050	COG1770	oligopeptidase
H1Y02_RS09055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1Y02_RS09065	COG2372	response to copper ion
H1Y02_RS09070	COG1276	copper resistance
H1Y02_RS09085	COG2990	Protein conserved in bacteria
H1Y02_RS09110	COG3008	intermembrane lipid transfer
H1Y02_RS09115	COG2995	paraquat-inducible protein a
H1Y02_RS09120	COG1956	GAF domain-containing protein
H1Y02_RS09140	COG2814	Major facilitator Superfamily
H1Y02_RS09145	COG1414	Transcriptional regulator
H1Y02_RS09175	COG0768	penicillin binding
H1Y02_RS09180	COG2226	methyltransferase
H1Y02_RS09195	COG3716	PTS system mannose fructose sorbose family IID component
H1Y02_RS09200	COG3715	PTS system
H1Y02_RS09205	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS09205	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Y02_RS09210	COG1253	flavin adenine dinucleotide binding
H1Y02_RS09215	COG2200	EAL domain
H1Y02_RS09220	COG1760	l-serine dehydratase
H1Y02_RS09240	COG0251	oxidation-reduction process
H1Y02_RS09245	COG1199	ATP-dependent helicase activity
H1Y02_RS09255	COG3065	identical protein binding
H1Y02_RS09265	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H1Y02_RS09275	COG2894	cell division
H1Y02_RS09290	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1Y02_RS09320	COG2719	SpoVR family
H1Y02_RS09345	COG1619	proteins homologs of microcin C7 resistance protein MccF
H1Y02_RS09365	COG4774	siderophore transport
H1Y02_RS09375	COG2211	Major facilitator Superfamily
H1Y02_RS09385	COG2308	Evidence 4 Homologs of previously reported genes of
H1Y02_RS09405	COG3842	ATPase activity
H1Y02_RS09410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1Y02_RS09415	COG0395	ABC-type sugar transport system, permease component
H1Y02_RS09425	COG1653	transport
H1Y02_RS09430	COG1940	carbohydrate kinase activity
H1Y02_RS09445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Y02_RS09455	COG1174	glycine betaine transport
H1Y02_RS09475	COG0583	DNA-binding transcription factor activity
H1Y02_RS09515	COG1882	Formate acetyltransferase
H1Y02_RS09550	COG0583	DNA-binding transcription factor activity
H1Y02_RS09580	COG0583	DNA-binding transcription factor activity
H1Y02_RS09590	COG0564	pseudouridine synthase activity
H1Y02_RS09595	COG3122	Protein conserved in bacteria
H1Y02_RS09620	COG0012	GTP binding
H1Y02_RS09640	COG0659	secondary active sulfate transmembrane transporter activity
H1Y02_RS09670	COG2890	protein-(glutamine-N5) methyltransferase activity
H1Y02_RS09690	COG0387	Pfam Sodium calcium exchanger
H1Y02_RS09695	COG4572	Cation transport regulator
H1Y02_RS09700	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H1Y02_RS09710	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1Y02_RS09715	COG3707	response regulator
H1Y02_RS09720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1Y02_RS09730	COG1116	anion transmembrane transporter activity
H1Y02_RS09735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1Y02_RS09735	COG2146	nitrite reductase [NAD(P)H] activity
H1Y02_RS09740	COG0243	molybdopterin cofactor binding
H1Y02_RS09745	COG4932	domain protein
H1Y02_RS09750	COG2197	response regulator
H1Y02_RS09755	COG3850	Histidine kinase
H1Y02_RS09760	COG2223	nitrite transmembrane transporter activity
H1Y02_RS09765	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H1Y02_RS09770	COG1140	nitrate reductase beta subunit
H1Y02_RS09775	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H1Y02_RS09780	COG2181	nitrate reductase activity
H1Y02_RS09790	COG1522	sequence-specific DNA binding
H1Y02_RS09810	COG0788	formyltetrahydrofolate deformylase activity
H1Y02_RS09820	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1Y02_RS09825	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS09830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1Y02_RS09835	COG2916	Histone family protein nucleoid-structuring protein H-NS
H1Y02_RS09840	COG1435	thymidine kinase activity
H1Y02_RS09845	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS09845	COG1454	alcohol dehydrogenase
H1Y02_RS09855	COG2095	MarC family integral membrane protein
H1Y02_RS09860	COG4166	transmembrane transport
H1Y02_RS09865	COG0601	transmembrane transport
H1Y02_RS09870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Y02_RS09875	COG0444	Belongs to the ABC transporter superfamily
H1Y02_RS09885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Y02_RS09905	COG2353	YceI-like domain
H1Y02_RS09910	COG2350	Protein conserved in bacteria
H1Y02_RS09920	COG3001	Fructosamine kinase
H1Y02_RS09930	COG1105	Belongs to the carbohydrate kinase PfkB family
H1Y02_RS09935	COG3137	Salt-induced outer membrane protein
H1Y02_RS09975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1Y02_RS09975	COG0072	phenylalanine-tRNA ligase activity
H1Y02_RS09995	COG0583	DNA-binding transcription factor activity
H1Y02_RS10015	COG0386	Belongs to the glutathione peroxidase family
H1Y02_RS10025	COG0791	NLP P60 protein
H1Y02_RS10035	COG4256	Hemin uptake protein
H1Y02_RS10040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1Y02_RS10055	COG0574	Belongs to the PEP-utilizing enzyme family
H1Y02_RS10055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1Y02_RS10065	COG0628	permease
H1Y02_RS10070	COG0277	FAD linked oxidase domain protein
H1Y02_RS10070	COG0247	lactate metabolic process
H1Y02_RS10075	COG2050	protein possibly involved in aromatic compounds catabolism
H1Y02_RS10080	COG3039	Transposase
H1Y02_RS10085	COG2261	transglycosylase associated protein
H1Y02_RS10100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H1Y02_RS10110	COG1120	ATPase activity
H1Y02_RS10115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Y02_RS10125	COG0583	DNA-binding transcription factor activity
H1Y02_RS10150	COG1304	FMN binding
H1Y02_RS10165	COG0316	Belongs to the HesB IscA family
H1Y02_RS10170	COG0719	Fe-S assembly protein
H1Y02_RS10175	COG0396	ATPase activity
H1Y02_RS10180	COG0719	Fe-S assembly protein
H1Y02_RS10195	COG1376	ErfK ybiS ycfS ynhG family protein
H1Y02_RS10220	COG1309	transcriptional regulator
H1Y02_RS10230	COG2271	Major facilitator Superfamily
H1Y02_RS10260	COG1414	Transcriptional regulator
H1Y02_RS10295	COG2814	Major facilitator Superfamily
H1Y02_RS10315	COG0583	DNA-binding transcription factor activity
H1Y02_RS10320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Y02_RS10340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Y02_RS10345	COG1116	anion transmembrane transporter activity
H1Y02_RS10350	COG4774	siderophore transport
H1Y02_RS10355	COG1120	ATPase activity
H1Y02_RS10360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Y02_RS10365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Y02_RS10370	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H1Y02_RS10385	COG0765	amino acid transport
H1Y02_RS10390	COG1126	abc transporter atp-binding protein
H1Y02_RS10420	COG3383	formate dehydrogenase (NAD+) activity
H1Y02_RS10425	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H1Y02_RS10435	COG1175	transmembrane transport
H1Y02_RS10465	COG4133	protoheme IX ABC transporter activity
H1Y02_RS10470	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H1Y02_RS10475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H1Y02_RS10490	COG1138	Cytochrome C-type biogenesis protein
H1Y02_RS10500	COG4235	cytochrome complex assembly
H1Y02_RS10500	COG3088	subunit of a heme lyase
H1Y02_RS10520	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
H1Y02_RS10535	COG3850	Histidine kinase
H1Y02_RS10535	COG5002	protein histidine kinase activity
H1Y02_RS10540	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS10585	COG3335	DDE superfamily endonuclease
H1Y02_RS10610	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS10615	COG2610	gluconate transmembrane transporter activity
H1Y02_RS10620	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1Y02_RS10630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1Y02_RS10640	COG0583	DNA-binding transcription factor activity
H1Y02_RS10670	COG2814	Major facilitator Superfamily
H1Y02_RS10705	COG0277	FAD linked oxidase domain protein
H1Y02_RS10710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Y02_RS10735	COG0402	S-adenosylhomocysteine deaminase activity
H1Y02_RS10765	COG0583	DNA-binding transcription factor activity
H1Y02_RS10790	COG3335	DDE superfamily endonuclease
H1Y02_RS10810	COG0583	DNA-binding transcription factor activity
H1Y02_RS10830	COG4608	Belongs to the ABC transporter superfamily
H1Y02_RS10835	COG0444	Belongs to the ABC transporter superfamily
H1Y02_RS10860	COG0346	lactoylglutathione lyase activity
H1Y02_RS10865	COG1349	DNA-binding transcription factor activity
H1Y02_RS10880	COG0604	alcohol dehydrogenase
H1Y02_RS10880	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS10880	COG3321	synthase
H1Y02_RS10900	COG3335	DDE superfamily endonuclease
H1Y02_RS10910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Y02_RS10930	COG0300	oxidoreductase activity
H1Y02_RS10970	COG0307	riboflavin synthase, alpha
H1Y02_RS10975	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H1Y02_RS10980	COG2814	Major facilitator Superfamily
H1Y02_RS10985	COG0583	DNA-binding transcription factor activity
H1Y02_RS11000	COG2814	Major facilitator Superfamily
H1Y02_RS11015	COG0791	NLP P60 protein
H1Y02_RS11020	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1Y02_RS11030	COG0346	lactoylglutathione lyase activity
H1Y02_RS11035	COG1902	pentaerythritol trinitrate reductase activity
H1Y02_RS11040	COG1309	transcriptional regulator
H1Y02_RS11045	COG3313	Fe-S protein
H1Y02_RS11050	COG4989	oxidoreductase activity
H1Y02_RS11055	COG2032	superoxide dismutase activity
H1Y02_RS11060	COG1289	transmembrane transporter activity
H1Y02_RS11065	COG1566	PFAM secretion protein HlyD family protein
H1Y02_RS11080	COG3706	GGDEF domain
H1Y02_RS11095	COG3895	Periplasmic Protein
H1Y02_RS11115	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H1Y02_RS11120	COG0625	glutathione transferase activity
H1Y02_RS11130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1Y02_RS11140	COG4659	FMN binding
H1Y02_RS11175	COG2723	6-phospho-beta-galactosidase activity
H1Y02_RS11185	COG0673	inositol 2-dehydrogenase activity
H1Y02_RS11195	COG2814	Major facilitator Superfamily
H1Y02_RS11215	COG3038	cytochrome b561
H1Y02_RS11235	COG0583	DNA-binding transcription factor activity
H1Y02_RS11240	COG3485	protocatechuate 3,4-dioxygenase
H1Y02_RS11245	COG3485	protocatechuate 3,4-dioxygenase
H1Y02_RS11250	COG5383	Protein conserved in bacteria
H1Y02_RS11255	COG2272	Belongs to the type-B carboxylesterase lipase family
H1Y02_RS11265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Y02_RS11270	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1Y02_RS11275	COG1275	C4-dicarboxylate transporter malic acid transport protein
H1Y02_RS11280	COG0500	methyltransferase
H1Y02_RS11290	COG0697	spore germination
H1Y02_RS11295	COG2207	Transcriptional regulator
H1Y02_RS11295	COG3708	Transcriptional regulator
H1Y02_RS11300	COG3135	benzoate transporter
H1Y02_RS11305	COG1396	sequence-specific DNA binding
H1Y02_RS11315	COG0826	peptidase U32
H1Y02_RS11335	COG1294	oxidase, subunit
H1Y02_RS11340	COG1271	oxidase subunit
H1Y02_RS11345	COG3039	Transposase
H1Y02_RS11375	COG0747	negative chemotaxis
H1Y02_RS11385	COG3238	Protein conserved in bacteria
H1Y02_RS11390	COG1247	-acetyltransferase
H1Y02_RS11400	COG2130	NADP-dependent
H1Y02_RS11410	COG3691	Protein conserved in bacteria
H1Y02_RS11415	COG4772	TonB-dependent receptor
H1Y02_RS11435	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H1Y02_RS11440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1Y02_RS11445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H1Y02_RS11450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Y02_RS11455	COG1473	amidohydrolase
H1Y02_RS11460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Y02_RS11475	COG0765	amino acid transport
H1Y02_RS11480	COG1126	abc transporter atp-binding protein
H1Y02_RS11490	COG0625	glutathione transferase activity
H1Y02_RS11500	COG3039	Transposase
H1Y02_RS11510	COG2211	Major facilitator Superfamily
H1Y02_RS11525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1Y02_RS11530	COG3842	ATPase activity
H1Y02_RS11535	COG1840	ABC-type Fe3 transport system, periplasmic component
H1Y02_RS11540	COG1178	ABC-type Fe3 transport system permease component
H1Y02_RS11545	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H1Y02_RS11560	COG1414	Transcriptional regulator
H1Y02_RS11565	COG4948	Mandelate Racemase Muconate Lactonizing
H1Y02_RS11570	COG4829	muconolactone delta-isomerase
H1Y02_RS11575	COG3485	protocatechuate 3,4-dioxygenase
H1Y02_RS11610	COG0437	4 iron, 4 sulfur cluster binding
H1Y02_RS11615	COG2864	formate dehydrogenase
H1Y02_RS11630	COG2326	polyphosphate kinase activity
H1Y02_RS11640	COG2814	Major facilitator Superfamily
H1Y02_RS11650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Y02_RS11670	COG0747	negative chemotaxis
H1Y02_RS11675	COG1064	alcohol dehydrogenase
H1Y02_RS11690	COG0488	(ABC) transporter
H1Y02_RS11735	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS11740	COG3729	General stress protein
H1Y02_RS11750	COG3685	Protein conserved in bacteria
H1Y02_RS11760	COG0366	Alpha amylase catalytic
H1Y02_RS11770	COG2323	membrane
H1Y02_RS11780	COG3111	PFAM Bacterial OB fold (BOF) protein
H1Y02_RS11790	COG1764	response to oxidative stress
H1Y02_RS11815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H1Y02_RS11820	COG3781	membrane
H1Y02_RS11825	COG0243	molybdopterin cofactor binding
H1Y02_RS11830	COG0583	DNA-binding transcription factor activity
H1Y02_RS11835	COG2814	Major facilitator Superfamily
H1Y02_RS11840	COG1285	pathogenesis
H1Y02_RS11845	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1Y02_RS11865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1Y02_RS11865	COG0519	Catalyzes the synthesis of GMP from XMP
H1Y02_RS11905	COG0596	Alpha beta hydrolase
H1Y02_RS11910	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS11915	COG2205	protein histidine kinase activity
H1Y02_RS11925	COG0583	DNA-binding transcription factor activity
H1Y02_RS11930	COG0076	glutamate decarboxylase activity
H1Y02_RS11935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1Y02_RS11940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1Y02_RS11945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Y02_RS11950	COG1116	anion transmembrane transporter activity
H1Y02_RS11955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1Y02_RS11975	COG0673	inositol 2-dehydrogenase activity
H1Y02_RS11985	COG1609	Transcriptional regulator
H1Y02_RS11990	COG3706	GGDEF domain
H1Y02_RS12000	COG0402	S-adenosylhomocysteine deaminase activity
H1Y02_RS12005	COG1953	Uracil, thiamine, allantoin
H1Y02_RS12040	COG0406	alpha-ribazole phosphatase activity
H1Y02_RS12050	COG3039	Transposase
H1Y02_RS12060	COG0583	DNA-binding transcription factor activity
H1Y02_RS12075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1Y02_RS12155	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H1Y02_RS12165	COG2070	2-Nitropropane dioxygenase
H1Y02_RS12170	COG0583	DNA-binding transcription factor activity
H1Y02_RS12180	COG1902	pentaerythritol trinitrate reductase activity
H1Y02_RS12185	COG4529	Protein conserved in bacteria
H1Y02_RS12190	COG0477	Major facilitator Superfamily
H1Y02_RS12220	COG2223	nitrite transmembrane transporter activity
H1Y02_RS12235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1Y02_RS12235	COG1116	anion transmembrane transporter activity
H1Y02_RS12245	COG3665	Urea carboxylase-associated protein
H1Y02_RS12250	COG0439	Biotin carboxylase
H1Y02_RS12340	COG0583	DNA-binding transcription factor activity
H1Y02_RS12350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Y02_RS12365	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS12375	COG1609	Transcriptional regulator
H1Y02_RS12410	COG2801	Transposase and inactivated derivatives
H1Y02_RS12425	COG5002	protein histidine kinase activity
H1Y02_RS12460	COG2186	Transcriptional regulator
H1Y02_RS12475	COG2814	Major facilitator Superfamily
H1Y02_RS12480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS12480	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS12495	COG2819	hydrolase of the alpha beta superfamily
H1Y02_RS12500	COG5001	Diguanylate cyclase
H1Y02_RS12500	COG3300	MHYT domain
H1Y02_RS12520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1Y02_RS12545	COG3550	peptidyl-serine autophosphorylation
H1Y02_RS12550	COG1396	sequence-specific DNA binding
H1Y02_RS12555	COG2351	hydroxyisourate hydrolase activity
H1Y02_RS12560	COG3648	Uricase
H1Y02_RS12560	COG3195	allantoin biosynthetic process
H1Y02_RS12565	COG2233	PERMEase
H1Y02_RS12595	COG2207	Transcriptional regulator
H1Y02_RS12610	COG4628	conserved protein (DUF2132)
H1Y02_RS12630	COG2011	ABC-type metal ion transport system permease component
H1Y02_RS12635	COG2070	2-Nitropropane dioxygenase
H1Y02_RS12690	COG2199	diguanylate cyclase activity
H1Y02_RS12705	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS12710	COG0583	DNA-binding transcription factor activity
H1Y02_RS12720	COG0039	L-malate dehydrogenase activity
H1Y02_RS12750	COG4977	sequence-specific DNA binding
H1Y02_RS12760	COG0697	spore germination
H1Y02_RS12765	COG2814	Major facilitator Superfamily
H1Y02_RS12780	COG1129	ABC transporter
H1Y02_RS12800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H1Y02_RS12835	COG2223	nitrite transmembrane transporter activity
H1Y02_RS12855	COG1349	DNA-binding transcription factor activity
H1Y02_RS12860	COG2084	Dehydrogenase
H1Y02_RS12865	COG3395	kinase activity
H1Y02_RS12870	COG0235	Class ii aldolase
H1Y02_RS12875	COG3622	Belongs to the hyi family
H1Y02_RS12880	COG2610	gluconate transmembrane transporter activity
H1Y02_RS12885	COG2207	Transcriptional regulator
H1Y02_RS12885	COG3708	Transcriptional regulator
H1Y02_RS12895	COG2200	EAL domain
H1Y02_RS12900	COG1546	Belongs to the CinA family
H1Y02_RS12905	COG0071	Belongs to the small heat shock protein (HSP20) family
H1Y02_RS12915	COG2135	peptidase activity
H1Y02_RS12920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Y02_RS12940	COG4221	oxidoreductase activity
H1Y02_RS12945	COG1802	Transcriptional regulator
H1Y02_RS12955	COG0246	Mannitol dehydrogenase
H1Y02_RS12960	COG2271	Major facilitator Superfamily
H1Y02_RS12975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Y02_RS12990	COG0243	molybdopterin cofactor binding
H1Y02_RS12995	COG0437	4 iron, 4 sulfur cluster binding
H1Y02_RS13000	COG3302	dmso reductase anchor subunit
H1Y02_RS13015	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H1Y02_RS13035	COG0583	DNA-binding transcription factor activity
H1Y02_RS13040	COG2814	Major facilitator Superfamily
H1Y02_RS13045	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H1Y02_RS13050	COG3039	Transposase
H1Y02_RS13060	COG3591	Belongs to the peptidase S1B family
H1Y02_RS13080	COG0628	permease
H1Y02_RS13110	COG0679	Auxin Efflux Carrier
H1Y02_RS13120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1Y02_RS13145	COG3290	protein histidine kinase activity
H1Y02_RS13150	COG4565	transcriptional regulatory protein
H1Y02_RS13160	COG1053	succinate dehydrogenase
H1Y02_RS13170	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1Y02_RS13170	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1Y02_RS13180	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1Y02_RS13185	COG0596	Alpha beta hydrolase
H1Y02_RS13195	COG0183	Belongs to the thiolase family
H1Y02_RS13200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1Y02_RS13210	COG1414	Transcriptional regulator
H1Y02_RS13215	COG2840	Smr protein MutS2
H1Y02_RS13220	COG0583	DNA-binding transcription factor activity
H1Y02_RS13230	COG1473	amidohydrolase
H1Y02_RS13235	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H1Y02_RS13250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Y02_RS13265	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H1Y02_RS13270	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H1Y02_RS13285	COG0531	amino acid
H1Y02_RS13295	COG3136	membrane protein required for alginate biosynthesis
H1Y02_RS13300	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS13310	COG2205	protein histidine kinase activity
H1Y02_RS13320	COG0114	fumarate hydratase activity
H1Y02_RS13325	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1Y02_RS13325	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1Y02_RS13330	COG1482	cell wall glycoprotein biosynthetic process
H1Y02_RS13335	COG5339	Protein conserved in bacteria
H1Y02_RS13340	COG1609	Transcriptional regulator
H1Y02_RS13345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Y02_RS13345	COG1263	PTS System
H1Y02_RS13350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H1Y02_RS13380	COG0425	Belongs to the sulfur carrier protein TusA family
H1Y02_RS13385	COG5562	phage envelope protein
H1Y02_RS13390	COG0401	homolog of Blt101
H1Y02_RS13395	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1Y02_RS13400	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS13410	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H1Y02_RS13415	COG0477	Major facilitator Superfamily
H1Y02_RS13420	COG1113	amino acid transport
H1Y02_RS13425	COG2988	succinylglutamate desuccinylase activity
H1Y02_RS13430	COG3724	N-succinylarginine dihydrolase activity
H1Y02_RS13435	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS13440	COG3138	arginine N-succinyltransferase
H1Y02_RS13445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1Y02_RS13455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1Y02_RS13470	COG0183	Belongs to the thiolase family
H1Y02_RS13480	COG0667	Aldo Keto reductase
H1Y02_RS13485	COG2814	Major facilitator Superfamily
H1Y02_RS13490	COG0667	Aldo Keto reductase
H1Y02_RS13495	COG0583	DNA-binding transcription factor activity
H1Y02_RS13520	COG4122	O-methyltransferase activity
H1Y02_RS13530	COG1643	Atp-dependent helicase
H1Y02_RS13545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1Y02_RS13550	COG3327	negative regulation of DNA-templated transcription, initiation
H1Y02_RS13555	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H1Y02_RS13560	COG0183	Belongs to the thiolase family
H1Y02_RS13565	COG2050	protein possibly involved in aromatic compounds catabolism
H1Y02_RS13570	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1Y02_RS13575	COG1024	Enoyl-CoA hydratase
H1Y02_RS13580	COG1024	Enoyl-CoA hydratase
H1Y02_RS13585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1Y02_RS13590	COG2151	metal-sulfur cluster biosynthetic enzyme
H1Y02_RS13595	COG3396	Phenylacetate-CoA oxygenase
H1Y02_RS13600	COG3460	Phenylacetate-CoA oxygenase
H1Y02_RS13605	COG3396	Phenylacetate-CoA oxygenase
H1Y02_RS13610	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS13610	COG2030	dehydratase
H1Y02_RS13650	COG2072	flavoprotein involved in K transport
H1Y02_RS13655	COG0583	DNA-binding transcription factor activity
H1Y02_RS13660	COG1126	abc transporter atp-binding protein
H1Y02_RS13670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Y02_RS13685	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS13690	COG2207	Transcriptional regulator
H1Y02_RS13695	COG3784	Protein of unknown function (DUF1318)
H1Y02_RS13705	COG2911	Protein conserved in bacteria
H1Y02_RS13710	COG0586	Pfam SNARE associated Golgi protein
H1Y02_RS13715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H1Y02_RS13720	COG3187	Heat shock protein
H1Y02_RS13725	COG3042	response to heat
H1Y02_RS13730	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1Y02_RS13730	COG0674	pyruvate-flavodoxin oxidoreductase activity
H1Y02_RS13730	COG1013	pyruvate-flavodoxin oxidoreductase activity
H1Y02_RS13730	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H1Y02_RS13735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H1Y02_RS13750	COG0589	response to stress
H1Y02_RS13760	COG0513	Belongs to the DEAD box helicase family
H1Y02_RS13770	COG1349	DNA-binding transcription factor activity
H1Y02_RS13775	COG0673	inositol 2-dehydrogenase activity
H1Y02_RS13790	COG1113	amino acid transport
H1Y02_RS13795	COG1522	sequence-specific DNA binding
H1Y02_RS13805	COG1448	Aminotransferase
H1Y02_RS13810	COG2011	ABC-type metal ion transport system permease component
H1Y02_RS13825	COG0436	Aminotransferase
H1Y02_RS13850	COG0583	DNA-binding transcription factor activity
H1Y02_RS13865	COG2207	Transcriptional regulator
H1Y02_RS13870	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS13950	COG5002	protein histidine kinase activity
H1Y02_RS13950	COG2205	protein histidine kinase activity
H1Y02_RS13950	COG0784	Response regulator, receiver
H1Y02_RS13955	COG3250	beta-galactosidase activity
H1Y02_RS13960	COG0656	L-ascorbic acid biosynthetic process
H1Y02_RS13995	COG2866	Carboxypeptidase
H1Y02_RS14000	COG4948	Mandelate Racemase Muconate Lactonizing
H1Y02_RS14005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H1Y02_RS14010	COG3180	Ammonia monooxygenase
H1Y02_RS14025	COG3106	COG3106 Predicted ATPase
H1Y02_RS14035	COG1983	PspC domain protein
H1Y02_RS14045	COG1842	Phage shock protein A
H1Y02_RS14050	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H1Y02_RS14060	COG1473	amidohydrolase
H1Y02_RS14075	COG0702	epimerase
H1Y02_RS14090	COG4171	peptide transport system, permease
H1Y02_RS14105	COG2986	histidine ammonia-lyase
H1Y02_RS14140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1Y02_RS14140	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1Y02_RS14155	COG1349	DNA-binding transcription factor activity
H1Y02_RS14165	COG0023	Translation Initiation Factor
H1Y02_RS14175	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H1Y02_RS14180	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
H1Y02_RS14185	COG0671	phosphoesterase, PA-phosphatase related
H1Y02_RS14195	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1Y02_RS14200	COG3039	Transposase
H1Y02_RS14220	COG0616	signal peptide processing
H1Y02_RS14225	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS14230	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H1Y02_RS14240	COG0583	DNA-binding transcription factor activity
H1Y02_RS14250	COG0009	L-threonylcarbamoyladenylate synthase
H1Y02_RS14260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1Y02_RS14265	COG0512	Glutamine amidotransferase of anthranilate synthase
H1Y02_RS14265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1Y02_RS14270	COG0135	phosphoribosylanthranilate isomerase activity
H1Y02_RS14270	COG0134	indole-3-glycerol-phosphate synthase activity
H1Y02_RS14305	COG4774	siderophore transport
H1Y02_RS14315	COG3047	cAMP biosynthetic process
H1Y02_RS14320	COG0727	PFAM Uncharacterised protein family (UPF0153)
H1Y02_RS14350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1Y02_RS14355	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS14360	COG1988	membrane-bound metal-dependent
H1Y02_RS14375	COG0753	catalase activity
H1Y02_RS14385	COG1486	melibiose metabolic process
H1Y02_RS14390	COG1917	Cupin 2, conserved barrel domain protein
H1Y02_RS14390	COG2169	Transcriptional regulator
H1Y02_RS14395	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1Y02_RS14400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Y02_RS14415	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Y02_RS14420	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1Y02_RS14430	COG0322	excinuclease ABC activity
H1Y02_RS14435	COG3678	ATP-independent chaperone mediated protein folding
H1Y02_RS14445	COG3724	N-succinylarginine dihydrolase activity
H1Y02_RS14455	COG3138	arginine N-succinyltransferase
H1Y02_RS14465	COG0708	Exodeoxyribonuclease III
H1Y02_RS14470	COG0398	Pfam SNARE associated Golgi protein
H1Y02_RS14475	COG0398	Pfam SNARE associated Golgi protein
H1Y02_RS14480	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1Y02_RS14485	COG4134	Bacterial extracellular solute-binding protein
H1Y02_RS14490	COG4135	transport system, permease component
H1Y02_RS14495	COG4136	ATPase activity
H1Y02_RS14500	COG2897	thiosulfate sulfurtransferase activity
H1Y02_RS14505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1Y02_RS14510	COG0494	nUDIX hydrolase
H1Y02_RS14515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1Y02_RS14520	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS14520	COG3321	synthase
H1Y02_RS14520	COG0604	alcohol dehydrogenase
H1Y02_RS14525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H1Y02_RS14530	COG0709	Synthesizes selenophosphate from selenide and ATP
H1Y02_RS14540	COG0778	Nitroreductase
H1Y02_RS14545	COG0616	signal peptide processing
H1Y02_RS14550	COG0252	asparaginase activity
H1Y02_RS14555	COG1335	isochorismatase
H1Y02_RS14570	COG3139	Protein of unknown function (DUF1315)
H1Y02_RS14590	COG0656	L-ascorbic acid biosynthetic process
H1Y02_RS14595	COG3713	MltA-interacting MipA family protein
H1Y02_RS14600	COG2766	serine protein kinase
H1Y02_RS14610	COG0386	Belongs to the glutathione peroxidase family
H1Y02_RS14645	COG1126	abc transporter atp-binding protein
H1Y02_RS14650	COG0765	amino acid transport
H1Y02_RS14655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Y02_RS14670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H1Y02_RS14680	COG0583	DNA-binding transcription factor activity
H1Y02_RS14685	COG1902	pentaerythritol trinitrate reductase activity
H1Y02_RS14695	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS14700	COG0583	DNA-binding transcription factor activity
H1Y02_RS14710	COG4974	Belongs to the 'phage' integrase family
H1Y02_RS14730	COG5642	Protein of unknown function (DUF2384)
H1Y02_RS14755	COG3039	Transposase
H1Y02_RS14780	COG3344	reverse transcriptase
H1Y02_RS14790	COG0859	PFAM glycosyl transferase family 9
H1Y02_RS14795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1Y02_RS14805	COG2207	Transcriptional regulator
H1Y02_RS14810	COG2807	transmembrane transport
H1Y02_RS14815	COG0504	CTP synthase activity
H1Y02_RS14820	COG1683	Conserved Protein
H1Y02_RS14825	COG3189	MarR family transcriptional regulator
H1Y02_RS14830	COG3042	response to heat
H1Y02_RS14980	COG4695	Portal protein
H1Y02_RS15000	COG3039	Transposase
H1Y02_RS15020	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H1Y02_RS15060	COG4974	Belongs to the 'phage' integrase family
H1Y02_RS15065	COG2203	Gaf domain
H1Y02_RS15065	COG2199	diguanylate cyclase activity
H1Y02_RS15085	COG3182	Iron-regulated membrane protein
H1Y02_RS15095	COG1560	Kdo2-lipid A biosynthetic process
H1Y02_RS15105	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H1Y02_RS15110	COG3706	GGDEF domain
H1Y02_RS15115	COG0583	DNA-binding transcription factor activity
H1Y02_RS15120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H1Y02_RS15130	COG2200	EAL domain
H1Y02_RS15130	COG2771	luxR family
H1Y02_RS15155	COG1294	oxidase, subunit
H1Y02_RS15160	COG1271	oxidase subunit
H1Y02_RS15165	COG3546	catalase activity
H1Y02_RS15170	COG3685	Protein conserved in bacteria
H1Y02_RS15175	COG3685	Protein conserved in bacteria
H1Y02_RS15180	COG3729	General stress protein
H1Y02_RS15185	COG1063	alcohol dehydrogenase
H1Y02_RS15190	COG3813	Protein conserved in bacteria
H1Y02_RS15225	COG0538	isocitrate dehydrogenase activity
H1Y02_RS15230	COG1187	pseudouridine synthase activity
H1Y02_RS15250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1Y02_RS15270	COG2205	protein histidine kinase activity
H1Y02_RS15275	COG2850	peptidyl-arginine hydroxylation
H1Y02_RS15280	COG1943	Transposase
H1Y02_RS15300	COG1177	transmembrane transport
H1Y02_RS15315	COG0318	PFAM AMP-dependent synthetase and ligase
H1Y02_RS15325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1Y02_RS15335	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1Y02_RS15345	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1Y02_RS15355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1Y02_RS15360	COG1388	LysM domain
H1Y02_RS15360	COG1376	ErfK ybiS ycfS ynhG family protein
H1Y02_RS15375	COG1309	transcriptional regulator
H1Y02_RS15385	COG3134	Outer membrane lipoprotein
H1Y02_RS15390	COG1252	NADH dehydrogenase
H1Y02_RS15415	COG5633	Lipoprotein
H1Y02_RS15420	COG0537	adenosine 5'-monophosphoramidase activity
H1Y02_RS15430	COG0084	hydrolase, TatD family'
H1Y02_RS15435	COG0470	DNA polymerase III
H1Y02_RS15445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1Y02_RS15450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1Y02_RS15455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1Y02_RS15470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1Y02_RS15490	COG1399	metal-binding, possibly nucleic acid-binding protein
H1Y02_RS15510	COG1530	ribonuclease E activity
H1Y02_RS15515	COG0583	DNA-binding transcription factor activity
H1Y02_RS15520	COG2814	Major facilitator Superfamily
H1Y02_RS15525	COG0728	peptidoglycan biosynthetic process
H1Y02_RS15540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Y02_RS15585	COG1560	Kdo2-lipid A biosynthetic process
H1Y02_RS15600	COG5645	(Lipo)protein
H1Y02_RS15635	COG3381	protein complex oligomerization
H1Y02_RS15665	COG0583	DNA-binding transcription factor activity
H1Y02_RS15675	COG1335	isochorismatase
H1Y02_RS15685	COG1702	phosphate starvation-inducible protein PhoH
H1Y02_RS15705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H1Y02_RS15715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1Y02_RS15730	COG1309	transcriptional regulator
H1Y02_RS15765	COG2233	PERMEase
H1Y02_RS15775	COG3729	General stress protein
H1Y02_RS15820	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS15835	COG0531	amino acid
H1Y02_RS15840	COG0174	glutamine synthetase
H1Y02_RS15845	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H1Y02_RS15850	COG1917	Cupin 2, conserved barrel domain protein
H1Y02_RS15850	COG1396	sequence-specific DNA binding
H1Y02_RS15855	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS15860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1Y02_RS15865	COG0583	DNA-binding transcription factor activity
H1Y02_RS15870	COG0473	3-isopropylmalate dehydrogenase activity
H1Y02_RS15875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1Y02_RS15880	COG4638	Rieske (2fe-2S)
H1Y02_RS15885	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS15890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1Y02_RS15895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS15895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1Y02_RS15895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS15900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1Y02_RS15905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1Y02_RS15910	COG1882	Formate acetyltransferase
H1Y02_RS15915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1Y02_RS15920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1Y02_RS15930	COG2207	Transcriptional regulator
H1Y02_RS15935	COG3706	GGDEF domain
H1Y02_RS15955	COG2200	EAL domain
H1Y02_RS15970	COG3039	Transposase
H1Y02_RS15990	COG0670	Belongs to the BI1 family
H1Y02_RS16005	COG2207	Transcriptional regulator
H1Y02_RS16010	COG1881	PFAM PEBP family protein
H1Y02_RS16025	COG1832	CoA-binding protein
H1Y02_RS16035	COG0210	DNA helicase
H1Y02_RS16040	COG3304	Inner membrane component domain
H1Y02_RS16045	COG1289	transmembrane transporter activity
H1Y02_RS16050	COG3070	regulator of competence-specific genes
H1Y02_RS16075	COG1067	ATP-dependent peptidase activity
H1Y02_RS16085	COG3130	regulation of translation
H1Y02_RS16090	COG3009	Protein conserved in bacteria
H1Y02_RS16095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1Y02_RS16095	COG3008	intermembrane lipid transfer
H1Y02_RS16100	COG2995	paraquat-inducible protein a
H1Y02_RS16105	COG0488	(ABC) transporter
H1Y02_RS16115	COG0633	Ferredoxin
H1Y02_RS16115	COG3217	Mosc domain protein beta barrel domain protein
H1Y02_RS16130	COG0431	NADPH-dependent FMN reductase
H1Y02_RS16135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1Y02_RS16140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Y02_RS16145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Y02_RS16155	COG0308	aminopeptidase N
H1Y02_RS16160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H1Y02_RS16170	COG2801	Transposase and inactivated derivatives
H1Y02_RS16180	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H1Y02_RS16185	COG1448	Aminotransferase
H1Y02_RS16190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Y02_RS16195	COG3108	Peptidase M15
H1Y02_RS16200	COG2989	Protein conserved in bacteria
H1Y02_RS16210	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
H1Y02_RS16220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1Y02_RS16225	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H1Y02_RS16230	COG3173	Aminoglycoside phosphotransferase
H1Y02_RS16245	COG3214	Protein conserved in bacteria
H1Y02_RS16260	COG2333	competence protein COMEC
H1Y02_RS16260	COG0658	competence protein
H1Y02_RS16270	COG0539	negative regulation of cytoplasmic translation
H1Y02_RS16315	COG1879	ABC-type sugar transport system periplasmic component
H1Y02_RS16320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1Y02_RS16325	COG2390	Transcriptional regulator
H1Y02_RS16330	COG3959	Transketolase, thiamine diphosphate binding domain
H1Y02_RS16335	COG3958	Transketolase
H1Y02_RS16340	COG2977	Belongs to the P-Pant transferase superfamily
H1Y02_RS16345	COG4771	TonB-dependent receptor
H1Y02_RS16350	COG2382	esterase
H1Y02_RS16355	COG3251	PFAM MbtH domain protein
H1Y02_RS16360	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H1Y02_RS16360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Y02_RS16365	COG1120	ATPase activity
H1Y02_RS16370	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Y02_RS16375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Y02_RS16385	COG4592	Periplasmic binding protein
H1Y02_RS16390	COG1169	isochorismate synthase
H1Y02_RS16395	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1Y02_RS16400	COG1535	isochorismatase
H1Y02_RS16400	COG3433	isochorismatase activity
H1Y02_RS16405	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS16415	COG1966	Carbon starvation protein
H1Y02_RS16420	COG2879	small protein
H1Y02_RS16440	COG0371	Dehydrogenase
H1Y02_RS16445	COG1129	ABC transporter
H1Y02_RS16450	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS16480	COG2271	Major facilitator Superfamily
H1Y02_RS16485	COG0483	inositol monophosphate 1-phosphatase activity
H1Y02_RS16495	COG0402	S-adenosylhomocysteine deaminase activity
H1Y02_RS16505	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1Y02_RS16520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1Y02_RS16530	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS16535	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS16540	COG1129	ABC transporter
H1Y02_RS16565	COG0436	Aminotransferase
H1Y02_RS16570	COG1475	DNA binding
H1Y02_RS16575	COG3969	phosphoadenosine phosphosulfate
H1Y02_RS16580	COG0583	DNA-binding transcription factor activity
H1Y02_RS16585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1Y02_RS16605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1Y02_RS16610	COG3719	Belongs to the RNase T2 family
H1Y02_RS16615	COG3069	C4-dicarboxylate transmembrane transporter activity
H1Y02_RS16635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1Y02_RS16640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H1Y02_RS16650	COG0583	DNA-binding transcription factor activity
H1Y02_RS16665	COG1686	Belongs to the peptidase S11 family
H1Y02_RS16670	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1Y02_RS16675	COG0772	Belongs to the SEDS family
H1Y02_RS16680	COG0768	penicillin binding
H1Y02_RS16690	COG0799	negative regulation of ribosome biogenesis
H1Y02_RS16705	COG1466	dna polymerase III delta subunit
H1Y02_RS16720	COG2888	peptidyl-tyrosine sulfation
H1Y02_RS16730	COG2831	hemolysin activation secretion protein
H1Y02_RS16735	COG1126	abc transporter atp-binding protein
H1Y02_RS16740	COG0765	amino acid transport
H1Y02_RS16745	COG0765	amino acid transport
H1Y02_RS16770	COG1702	phosphate starvation-inducible protein PhoH
H1Y02_RS16780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1Y02_RS16820	COG0367	asparagine synthase
H1Y02_RS16825	COG0647	UMP catabolic process
H1Y02_RS16830	COG1940	carbohydrate kinase activity
H1Y02_RS16830	COG1846	Transcriptional regulator
H1Y02_RS16835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H1Y02_RS16880	COG1053	succinate dehydrogenase
H1Y02_RS16885	COG0583	DNA-binding transcription factor activity
H1Y02_RS16890	COG0735	belongs to the Fur family
H1Y02_RS16905	COG0596	Alpha beta hydrolase
H1Y02_RS16915	COG0033	Phosphoglucomutase
H1Y02_RS16925	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS16930	COG2205	protein histidine kinase activity
H1Y02_RS16975	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H1Y02_RS16980	COG1984	allophanate hydrolase subunit 2
H1Y02_RS17000	COG0372	Belongs to the citrate synthase family
H1Y02_RS17005	COG2009	succinate dehydrogenase
H1Y02_RS17010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H1Y02_RS17015	COG1053	succinate dehydrogenase
H1Y02_RS17020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1Y02_RS17025	COG0567	Dehydrogenase, E1 component
H1Y02_RS17030	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Y02_RS17040	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H1Y02_RS17045	COG1271	oxidase subunit
H1Y02_RS17050	COG1294	oxidase, subunit
H1Y02_RS17055	COG4890	Cyd operon protein YbgT
H1Y02_RS17060	COG3790	cyd operon protein YbgE
H1Y02_RS17065	COG0824	Thioesterase
H1Y02_RS17070	COG0811	peptide transport
H1Y02_RS17075	COG0848	biopolymer transport protein
H1Y02_RS17080	COG3064	Membrane
H1Y02_RS17080	COG3064	Membrane
H1Y02_RS17090	COG2885	chlorophyll binding
H1Y02_RS17095	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
H1Y02_RS17140	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H1Y02_RS17145	COG3201	nicotinamide mononucleotide transporter
H1Y02_RS17160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1Y02_RS17170	COG2017	converts alpha-aldose to the beta-anomer
H1Y02_RS17180	COG1085	galactose-1-phosphate uridylyltransferase
H1Y02_RS17190	COG1119	ATPase activity
H1Y02_RS17195	COG3585	molybdate ion transport
H1Y02_RS17195	COG2005	Transcriptional regulator
H1Y02_RS17205	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1Y02_RS17210	COG4149	molybdate abc transporter
H1Y02_RS17215	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H1Y02_RS17220	COG0561	phosphatase activity
H1Y02_RS17245	COG2200	EAL domain
H1Y02_RS17250	COG0789	Transcriptional regulator
H1Y02_RS17285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Y02_RS17290	COG0589	response to stress
H1Y02_RS17300	COG4677	pectinesterase activity
H1Y02_RS17340	COG1881	PFAM PEBP family protein
H1Y02_RS17345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H1Y02_RS17360	COG2226	methyltransferase
H1Y02_RS17385	COG0642	Histidine kinase
H1Y02_RS17390	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS17410	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1Y02_RS17420	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H1Y02_RS17425	COG0314	molybdopterin synthase activity
H1Y02_RS17430	COG0670	Belongs to the BI1 family
H1Y02_RS17435	COG0392	lysyltransferase activity
H1Y02_RS17440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1Y02_RS17445	COG3568	Endonuclease Exonuclease Phosphatase
H1Y02_RS17455	COG0842	Transport permease protein
H1Y02_RS17460	COG0842	Transport permease protein
H1Y02_RS17465	COG1131	(ABC) transporter
H1Y02_RS17470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Y02_RS17480	COG0583	DNA-binding transcription factor activity
H1Y02_RS17490	COG2271	Major facilitator Superfamily
H1Y02_RS17495	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS17500	COG3959	Transketolase, thiamine diphosphate binding domain
H1Y02_RS17505	COG3958	Transketolase
H1Y02_RS17510	COG0513	Belongs to the DEAD box helicase family
H1Y02_RS17520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1Y02_RS17530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1Y02_RS17540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1Y02_RS17550	COG0668	transmembrane transport
H1Y02_RS17555	COG1126	abc transporter atp-binding protein
H1Y02_RS17560	COG0765	amino acid transport
H1Y02_RS17565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Y02_RS17580	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1Y02_RS17585	COG2194	sulfuric ester hydrolase activity
H1Y02_RS17595	COG1321	iron dependent repressor
H1Y02_RS17600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H1Y02_RS17605	COG2723	6-phospho-beta-galactosidase activity
H1Y02_RS17610	COG2188	Transcriptional regulator
H1Y02_RS17615	COG1376	ErfK ybiS ycfS ynhG family protein
H1Y02_RS17625	COG0488	(ABC) transporter
H1Y02_RS17635	COG2271	Major facilitator Superfamily
H1Y02_RS17640	COG1609	Transcriptional regulator
H1Y02_RS17650	COG0561	phosphatase activity
H1Y02_RS17655	COG1882	Formate acetyltransferase
H1Y02_RS17660	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1Y02_RS17665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H1Y02_RS17670	COG0303	'Molybdopterin
H1Y02_RS17675	COG1446	asparaginase
H1Y02_RS17715	COG2133	pyrroloquinoline quinone binding
H1Y02_RS17720	COG0625	glutathione transferase activity
H1Y02_RS17725	COG1686	Belongs to the peptidase S11 family
H1Y02_RS17730	COG1349	DNA-binding transcription factor activity
H1Y02_RS17735	COG0671	phosphoesterase, PA-phosphatase related
H1Y02_RS17740	COG2814	Major facilitator Superfamily
H1Y02_RS17745	COG0561	phosphatase activity
H1Y02_RS17750	COG0738	Major facilitator superfamily
H1Y02_RS17755	COG3226	Transcriptional regulator
H1Y02_RS17795	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H1Y02_RS17800	COG3842	ATPase activity
H1Y02_RS17805	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1Y02_RS17810	COG1177	transmembrane transport
H1Y02_RS17825	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS17830	COG5002	protein histidine kinase activity
H1Y02_RS17835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Y02_RS17840	COG4160	amino acid transport
H1Y02_RS17845	COG4215	(ABC) transporter
H1Y02_RS17850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Y02_RS17855	COG1126	abc transporter atp-binding protein
H1Y02_RS17870	COG2203	Gaf domain
H1Y02_RS17870	COG3706	GGDEF domain
H1Y02_RS17870	COG5001	Diguanylate cyclase
H1Y02_RS17870	COG4251	negative regulation of phosphorylation
H1Y02_RS17875	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1Y02_RS17880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Y02_RS17885	COG0702	epimerase
H1Y02_RS17890	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
H1Y02_RS17895	COG0028	Belongs to the TPP enzyme family
H1Y02_RS17905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1Y02_RS17915	COG2431	L-lysine efflux transmembrane transporter activity
H1Y02_RS17925	COG3593	DNA synthesis involved in DNA repair
H1Y02_RS17930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Y02_RS17940	COG1278	Cold shock
H1Y02_RS17950	COG0542	response to heat
H1Y02_RS17965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H1Y02_RS17970	COG4988	ABC transporter
H1Y02_RS17975	COG0492	ferredoxin-NADP+ reductase activity
H1Y02_RS17985	COG1178	ABC-type Fe3 transport system permease component
H1Y02_RS17985	COG1674	ftsk spoiiie
H1Y02_RS17995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1Y02_RS18005	COG0243	molybdopterin cofactor binding
H1Y02_RS18010	COG0437	4 iron, 4 sulfur cluster binding
H1Y02_RS18015	COG3302	dmso reductase anchor subunit
H1Y02_RS18020	COG0477	Major facilitator Superfamily
H1Y02_RS18025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1Y02_RS18030	COG1882	Formate acetyltransferase
H1Y02_RS18035	COG2116	formate transmembrane transporter activity
H1Y02_RS18050	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS18060	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS18070	COG0583	DNA-binding transcription factor activity
H1Y02_RS18075	COG0668	transmembrane transport
H1Y02_RS18085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1Y02_RS18120	COG3039	Transposase
H1Y02_RS18150	COG3039	Transposase
H1Y02_RS18165	COG0747	negative chemotaxis
H1Y02_RS18170	COG0601	transmembrane transport
H1Y02_RS18175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Y02_RS18180	COG0444	Belongs to the ABC transporter superfamily
H1Y02_RS18185	COG4608	Belongs to the ABC transporter superfamily
H1Y02_RS18195	COG4221	oxidoreductase activity
H1Y02_RS18205	COG4215	(ABC) transporter
H1Y02_RS18210	COG3039	Transposase
H1Y02_RS18220	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
H1Y02_RS18230	COG0436	Aminotransferase
H1Y02_RS18235	COG0697	spore germination
H1Y02_RS18250	COG4608	Belongs to the ABC transporter superfamily
H1Y02_RS18255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Y02_RS18275	COG3698	Phosphodiester glycosidase
H1Y02_RS18315	COG2315	Protein conserved in bacteria
H1Y02_RS18320	COG0778	Nitroreductase
H1Y02_RS18345	COG0477	Major facilitator Superfamily
H1Y02_RS18350	COG0668	transmembrane transport
H1Y02_RS18375	COG2211	Major facilitator Superfamily
H1Y02_RS18380	COG1113	amino acid transport
H1Y02_RS18385	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS18390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1Y02_RS18400	COG0531	amino acid
H1Y02_RS18445	COG0667	Aldo Keto reductase
H1Y02_RS18450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Y02_RS18455	COG1473	amidohydrolase
H1Y02_RS18480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Y02_RS18485	COG1120	ATPase activity
H1Y02_RS18490	COG1566	PFAM secretion protein HlyD family protein
H1Y02_RS18535	COG4211	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS18540	COG1129	ABC transporter
H1Y02_RS18555	COG0673	inositol 2-dehydrogenase activity
H1Y02_RS18580	COG3039	Transposase
H1Y02_RS18595	COG3039	Transposase
H1Y02_RS18605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1Y02_RS18690	COG4386	tail sheath protein
H1Y02_RS18730	COG0616	signal peptide processing
H1Y02_RS18770	COG3772	lysozyme
H1Y02_RS18785	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H1Y02_RS18950	COG2501	S4 domain
H1Y02_RS18960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1Y02_RS18975	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H1Y02_RS18980	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1Y02_RS18985	COG0549	Belongs to the carbamate kinase family
H1Y02_RS18995	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H1Y02_RS19000	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H1Y02_RS19010	COG3039	Transposase
H1Y02_RS19015	COG1929	Belongs to the glycerate kinase type-1 family
H1Y02_RS19020	COG2233	PERMEase
H1Y02_RS19030	COG1953	Uracil, thiamine, allantoin
H1Y02_RS19040	COG2084	Dehydrogenase
H1Y02_RS19045	COG3622	Belongs to the hyi family
H1Y02_RS19050	COG3960	tartronate-semialdehyde synthase activity
H1Y02_RS19085	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H1Y02_RS19090	COG4181	ATPase activity
H1Y02_RS19095	COG2755	lipolytic protein G-D-S-L family
H1Y02_RS19100	COG0300	oxidoreductase activity
H1Y02_RS19105	COG3118	belongs to the thioredoxin family
H1Y02_RS19110	COG0390	transport system, permease component
H1Y02_RS19115	COG4619	ABC transporter
H1Y02_RS19120	COG0330	HflC and HflK could
H1Y02_RS19125	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1Y02_RS19140	COG3735	TraB family
H1Y02_RS19145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1Y02_RS19155	COG2223	nitrite transmembrane transporter activity
H1Y02_RS19160	COG4651	solute:proton antiporter activity
H1Y02_RS19160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1Y02_RS19165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1Y02_RS19205	COG2832	Protein of unknown function (DUF454)
H1Y02_RS19210	COG3923	Primosomal replication protein n
H1Y02_RS19220	COG5464	transposase or invertase
H1Y02_RS19225	COG1196	nuclear chromosome segregation
H1Y02_RS19225	COG3264	Mechanosensitive ion channel
H1Y02_RS19230	COG1309	transcriptional regulator
H1Y02_RS19235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Y02_RS19240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Y02_RS19255	COG0110	maltose O-acetyltransferase activity
H1Y02_RS19305	COG1874	Beta-galactosidase
H1Y02_RS19310	COG3867	Arabinogalactan endo-beta-1,4-galactanase
H1Y02_RS19315	COG3833	ABC-type maltose transport systems, permease component
H1Y02_RS19320	COG1175	transmembrane transport
H1Y02_RS19325	COG2182	Extracellular solute-binding protein
H1Y02_RS19335	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H1Y02_RS19350	COG2364	Membrane
H1Y02_RS19380	COG3695	enzyme binding
H1Y02_RS19385	COG3126	Type III secretion system lipoprotein chaperone (YscW)
H1Y02_RS19390	COG1946	Acyl-CoA thioesterase
H1Y02_RS19395	COG0004	ammonium transporteR
H1Y02_RS19400	COG0347	Belongs to the P(II) protein family
H1Y02_RS19405	COG1132	(ABC) transporter
H1Y02_RS19410	COG1132	(ABC) transporter
H1Y02_RS19415	COG1522	sequence-specific DNA binding
H1Y02_RS19430	COG4533	DNA binding
H1Y02_RS19440	COG0824	Thioesterase
H1Y02_RS19445	COG1555	photosystem II stabilization
H1Y02_RS19450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1Y02_RS19455	COG0776	regulation of translation
H1Y02_RS19460	COG3039	Transposase
H1Y02_RS19465	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H1Y02_RS19485	COG0271	Belongs to the BolA IbaG family
H1Y02_RS19490	COG3056	Lipoprotein
H1Y02_RS19495	COG2223	nitrite transmembrane transporter activity
H1Y02_RS19500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1Y02_RS19505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1Y02_RS19510	COG1845	cytochrome c oxidase, subunit III
H1Y02_RS19515	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1Y02_RS19530	COG1414	Transcriptional regulator
H1Y02_RS19535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H1Y02_RS19540	COG1053	succinate dehydrogenase
H1Y02_RS19550	COG1053	succinate dehydrogenase
H1Y02_RS19565	COG0673	inositol 2-dehydrogenase activity
H1Y02_RS19570	COG2814	Major facilitator Superfamily
H1Y02_RS19580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H1Y02_RS19605	COG0142	geranyltranstransferase activity
H1Y02_RS19615	COG0667	Aldo Keto reductase
H1Y02_RS19620	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H1Y02_RS19640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1Y02_RS19640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1Y02_RS19650	COG4238	major outer membrane lipoprotein
H1Y02_RS19670	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1Y02_RS19675	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1Y02_RS19680	COG1862	Preprotein translocase
H1Y02_RS19705	COG0450	alkyl hydroperoxide reductase
H1Y02_RS19715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS19750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1Y02_RS19760	COG1228	amidohydrolase
H1Y02_RS19770	COG1335	isochorismatase
H1Y02_RS19775	COG0583	DNA-binding transcription factor activity
H1Y02_RS19780	COG0366	Alpha amylase catalytic
H1Y02_RS19805	COG0420	3'-5' exonuclease activity
H1Y02_RS19810	COG0419	ATPase involved in DNA repair
H1Y02_RS19815	COG1940	carbohydrate kinase activity
H1Y02_RS19830	COG4126	flavin adenine dinucleotide binding
H1Y02_RS19840	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H1Y02_RS19845	COG3416	Protein conserved in bacteria
H1Y02_RS19855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H1Y02_RS19865	COG1785	Belongs to the alkaline phosphatase family
H1Y02_RS19905	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H1Y02_RS19915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1Y02_RS19920	COG0113	porphobilinogen synthase activity
H1Y02_RS19930	COG2175	clavaminate synthase activity
H1Y02_RS19935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Y02_RS19940	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1Y02_RS19945	COG4521	taurine ABC transporter
H1Y02_RS19950	COG2040	homocysteine
H1Y02_RS19955	COG0833	amino acid
H1Y02_RS19965	COG0531	amino acid
H1Y02_RS19970	COG4303	Ethanolamine ammonia lyase large subunit
H1Y02_RS19975	COG4302	ethanolamine ammonia-lyase activity
H1Y02_RS20015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Y02_RS20020	COG1126	abc transporter atp-binding protein
H1Y02_RS20025	COG0765	amino acid transport
H1Y02_RS20030	COG0765	amino acid transport
H1Y02_RS20045	COG3188	usher protein
H1Y02_RS20070	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H1Y02_RS20080	COG3639	organic phosphonate transmembrane transporter activity
H1Y02_RS20095	COG0791	NLP P60 protein
H1Y02_RS20125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1Y02_RS20130	COG0022	dehydrogenase e1 component
H1Y02_RS20135	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Y02_RS20140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1Y02_RS20175	COG1070	Carbohydrate kinase
H1Y02_RS20180	COG1028	Short-chain dehydrogenase reductase Sdr
H1Y02_RS20185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1Y02_RS20190	COG3775	system Galactitol-specific IIC component
H1Y02_RS20195	COG0625	glutathione transferase activity
H1Y02_RS20200	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H1Y02_RS20215	COG0579	oxidoreductase
H1Y02_RS20220	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS20225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1Y02_RS20230	COG1113	amino acid transport
H1Y02_RS20235	COG1802	Transcriptional regulator
H1Y02_RS20255	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1Y02_RS20260	COG0454	-acetyltransferase
H1Y02_RS20275	COG2991	Protein conserved in bacteria
H1Y02_RS20290	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H1Y02_RS20295	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H1Y02_RS20310	COG3034	peptidoglycan biosynthetic process
H1Y02_RS20315	COG0121	glutamine amidotransferase
H1Y02_RS20325	COG1960	acyl-CoA dehydrogenase activity
H1Y02_RS20330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1Y02_RS20345	COG0583	DNA-binding transcription factor activity
H1Y02_RS20365	COG2226	methyltransferase
H1Y02_RS20375	COG0741	lytic transglycosylase activity
H1Y02_RS20375	COG1388	LysM domain
H1Y02_RS20380	COG2226	methyltransferase
H1Y02_RS20390	COG2814	Major facilitator Superfamily
H1Y02_RS20395	COG0583	DNA-binding transcription factor activity
H1Y02_RS20400	COG0656	L-ascorbic acid biosynthetic process
H1Y02_RS20435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H1Y02_RS20445	COG2011	ABC-type metal ion transport system permease component
H1Y02_RS20450	COG1464	Belongs to the NlpA lipoprotein family
H1Y02_RS20460	COG1720	tRNA m6t6A37 methyltransferase activity
H1Y02_RS20475	COG3015	lipoprotein NlpE involved in copper resistance
H1Y02_RS20480	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H1Y02_RS20495	COG4568	rho-dependent transcription termination
H1Y02_RS20505	COG0346	lactoylglutathione lyase activity
H1Y02_RS20520	COG0587	DNA-directed DNA polymerase activity
H1Y02_RS20550	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
H1Y02_RS20560	COG0750	zinc metalloprotease
H1Y02_RS20565	COG0575	Belongs to the CDS family
H1Y02_RS20600	COG0024	Methionine aminopeptidase
H1Y02_RS20605	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
H1Y02_RS20620	COG3835	regulator
H1Y02_RS20625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1Y02_RS20645	COG2860	membrane
H1Y02_RS20665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Y02_RS20670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H1Y02_RS20675	COG1120	ATPase activity
H1Y02_RS20680	COG4774	siderophore transport
H1Y02_RS20685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1Y02_RS20775	COG1643	Atp-dependent helicase
H1Y02_RS20780	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H1Y02_RS20800	COG0617	tRNA 3'-terminal CCA addition
H1Y02_RS20805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1Y02_RS20825	COG0726	polysaccharide deacetylase
H1Y02_RS20830	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS20835	COG0842	Transport permease protein
H1Y02_RS20840	COG1131	(ABC) transporter
H1Y02_RS20845	COG0288	reversible hydration of carbon dioxide
H1Y02_RS20980	COG3561	AntA/AntB antirepressor
H1Y02_RS21010	COG4993	Dehydrogenase
H1Y02_RS21015	COG2132	Multicopper oxidase
H1Y02_RS21055	COG3064	Membrane
H1Y02_RS21070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1Y02_RS21075	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Y02_RS21080	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H1Y02_RS21085	COG2186	Transcriptional regulator
H1Y02_RS21090	COG1113	amino acid transport
H1Y02_RS21095	COG2211	Major facilitator Superfamily
H1Y02_RS21100	COG3940	Belongs to the glycosyl hydrolase 43 family
H1Y02_RS21105	COG3725	Membrane protein required for beta-lactamase induction
H1Y02_RS21120	COG4969	Belongs to the N-Me-Phe pilin family
H1Y02_RS21125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1Y02_RS21130	COG1459	type II secretion system
H1Y02_RS21155	COG0494	nUDIX hydrolase
H1Y02_RS21175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1Y02_RS21180	COG0849	cell division
H1Y02_RS21205	COG0772	Belongs to the SEDS family
H1Y02_RS21220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1Y02_RS21230	COG0768	penicillin binding
H1Y02_RS21250	COG1609	Transcriptional regulator
H1Y02_RS21260	COG0028	Belongs to the TPP enzyme family
H1Y02_RS21270	COG3039	Transposase
H1Y02_RS21275	COG3039	Transposase
H1Y02_RS21310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H1Y02_RS21315	COG0738	Major facilitator superfamily
H1Y02_RS21325	COG0583	DNA-binding transcription factor activity
H1Y02_RS21330	COG2271	Major facilitator Superfamily
H1Y02_RS21335	COG2814	Major facilitator Superfamily
H1Y02_RS21355	COG1178	ABC-type Fe3 transport system permease component
H1Y02_RS21365	COG0586	Pfam SNARE associated Golgi protein
H1Y02_RS21390	COG0417	DNA replication proofreading
H1Y02_RS21400	COG0564	pseudouridine synthase activity
H1Y02_RS21410	COG3493	citrate carrier protein
H1Y02_RS21425	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H1Y02_RS21430	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H1Y02_RS21440	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H1Y02_RS21485	COG0505	Belongs to the CarA family
H1Y02_RS21495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H1Y02_RS21520	COG1047	Peptidyl-prolyl cis-trans
H1Y02_RS21535	COG0196	riboflavin kinase activity
H1Y02_RS21545	COG0583	DNA-binding transcription factor activity
H1Y02_RS21570	COG4735	regulation of single-species biofilm formation
H1Y02_RS21575	COG1584	GPR1 FUN34 yaaH family protein
H1Y02_RS21580	COG0477	Major facilitator Superfamily
H1Y02_RS21585	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1Y02_RS21590	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1Y02_RS21595	COG1115	amino acid carrier protein
H1Y02_RS21605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1Y02_RS21615	COG0527	aspartate kinase activity
H1Y02_RS21615	COG0460	homoserine dehydrogenase
H1Y02_RS21625	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
H1Y02_RS21635	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS21640	COG4452	Inner membrane protein CreD
H1Y02_RS21645	COG2205	protein histidine kinase activity
H1Y02_RS21650	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS21655	COG3045	CreA protein
H1Y02_RS21660	COG2207	Transcriptional regulator
H1Y02_RS21660	COG3708	Transcriptional regulator
H1Y02_RS21680	COG0741	lytic transglycosylase activity
H1Y02_RS21685	COG0488	(ABC) transporter
H1Y02_RS21695	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H1Y02_RS21700	COG0560	Phosphoserine phosphatase
H1Y02_RS21705	COG3726	membrane protein affecting hemolysin expression
H1Y02_RS21735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H1Y02_RS21740	COG0084	hydrolase, TatD family'
H1Y02_RS21745	COG4667	esterase of the alpha-beta hydrolase superfamily
H1Y02_RS21755	COG2823	Periplasmic or secreted lipoprotein
H1Y02_RS21765	COG1011	Hydrolase
H1Y02_RS21770	COG0456	acetyltransferase
H1Y02_RS21775	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
H1Y02_RS21810	COG3039	Transposase
H1Y02_RS21815	COG3706	GGDEF domain
H1Y02_RS21820	COG4114	ferric iron reductase
H1Y02_RS21825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Y02_RS21825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1Y02_RS21830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1Y02_RS21835	COG2197	response regulator
H1Y02_RS21840	COG2197	response regulator
H1Y02_RS21845	COG1917	Cupin 2, conserved barrel domain protein
H1Y02_RS21845	COG2169	Transcriptional regulator
H1Y02_RS21855	COG2966	Psort location CytoplasmicMembrane, score
H1Y02_RS21870	COG1484	DNA-dependent DNA replication
H1Y02_RS21885	COG5464	transposase or invertase
H1Y02_RS21890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1Y02_RS21895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1Y02_RS21900	COG3716	PTS system mannose fructose sorbose family IID component
H1Y02_RS21905	COG3715	PTS system
H1Y02_RS21920	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H1Y02_RS21920	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H1Y02_RS21925	COG0456	acetyltransferase
H1Y02_RS21925	COG1214	PFAM Peptidase M22, glycoprotease
H1Y02_RS21940	COG0531	amino acid
H1Y02_RS21945	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS21950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1Y02_RS21980	COG1846	Transcriptional regulator
H1Y02_RS21990	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1Y02_RS22000	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS22005	COG3384	dioxygenase
H1Y02_RS22015	COG3971	2-oxopent-4-enoate hydratase activity
H1Y02_RS22035	COG2368	4-hydroxyphenylacetate
H1Y02_RS22040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1Y02_RS22045	COG1966	Carbon starvation protein
H1Y02_RS22050	COG2879	small protein
H1Y02_RS22055	COG0523	cobalamin synthesis protein
H1Y02_RS22070	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS22075	COG5464	transposase or invertase
H1Y02_RS22080	COG1917	Cupin 2, conserved barrel domain protein
H1Y02_RS22080	COG2207	Transcriptional regulator
H1Y02_RS22090	COG2733	membrane
H1Y02_RS22095	COG2814	Major facilitator Superfamily
H1Y02_RS22105	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
H1Y02_RS22110	COG1924	4 iron, 4 sulfur cluster binding
H1Y02_RS22125	COG1566	PFAM secretion protein HlyD family protein
H1Y02_RS22135	COG5457	Domain of unknown function (DUF1127)
H1Y02_RS22140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Y02_RS22165	COG0583	DNA-binding transcription factor activity
H1Y02_RS22205	COG1454	alcohol dehydrogenase
H1Y02_RS22205	COG1012	belongs to the aldehyde dehydrogenase family
H1Y02_RS22220	COG1882	Formate acetyltransferase
H1Y02_RS22225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1Y02_RS22235	COG4869	propanediol catabolic process
H1Y02_RS22260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Y02_RS22265	COG1129	ABC transporter
H1Y02_RS22265	COG0842	Transport permease protein
H1Y02_RS22270	COG0842	Transport permease protein
H1Y02_RS22305	COG2850	peptidyl-arginine hydroxylation
H1Y02_RS22310	COG5002	protein histidine kinase activity
H1Y02_RS22315	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS22320	COG1538	Outer membrane efflux protein
H1Y02_RS22325	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Y02_RS22330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Y02_RS22335	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Y02_RS22345	COG3040	lipid binding
H1Y02_RS22350	COG0789	Transcriptional regulator
H1Y02_RS22360	COG0300	oxidoreductase activity
H1Y02_RS22375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H1Y02_RS22395	COG3272	Protein of unknown function (DUF1722)
H1Y02_RS22400	COG4580	involved in the transport of maltose and maltodextrins
H1Y02_RS22410	COG2211	Major facilitator Superfamily
H1Y02_RS22415	COG3507	Belongs to the glycosyl hydrolase 43 family
H1Y02_RS22495	COG0582	viral genome integration into host DNA
H1Y02_RS22505	COG0288	reversible hydration of carbon dioxide
H1Y02_RS22510	COG0659	secondary active sulfate transmembrane transporter activity
H1Y02_RS22515	COG1064	alcohol dehydrogenase
H1Y02_RS22520	COG1175	transmembrane transport
H1Y02_RS22525	COG0395	ABC-type sugar transport system, permease component
H1Y02_RS22530	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1Y02_RS22535	COG3842	ATPase activity
H1Y02_RS22550	COG1082	Xylose isomerase domain protein TIM barrel
H1Y02_RS22560	COG3962	Belongs to the TPP enzyme family
H1Y02_RS22565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1Y02_RS22570	COG0837	glucose binding
H1Y02_RS22570	COG1737	Transcriptional regulator
H1Y02_RS22575	COG3718	enzyme involved in inositol metabolism
H1Y02_RS22590	COG0433	COG0433 Predicted ATPase
H1Y02_RS22595	COG0795	lipopolysaccharide-transporting ATPase activity
H1Y02_RS22600	COG0795	lipopolysaccharide-transporting ATPase activity
H1Y02_RS22610	COG2927	DNA polymerase III (CHI subunit)
H1Y02_RS22615	COG0525	valine-tRNA ligase activity
H1Y02_RS22640	COG2731	YhcH YjgK YiaL family protein
H1Y02_RS22675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Y02_RS22675	COG1263	PTS System
H1Y02_RS22680	COG0366	Alpha amylase catalytic
H1Y02_RS22690	COG0602	queuosine metabolic process
H1Y02_RS22695	COG2026	Addiction module toxin, RelE StbE family
H1Y02_RS22700	COG3077	Addiction module antitoxin, RelB DinJ family
H1Y02_RS22705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Y02_RS22705	COG3711	transcriptional antiterminator
H1Y02_RS22710	COG2706	6-phosphogluconolactonase activity
H1Y02_RS22725	COG3964	amidohydrolase
H1Y02_RS22760	COG0312	modulator of DNA gyrase
H1Y02_RS22780	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1Y02_RS22790	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS22795	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS22800	COG1129	ABC transporter
H1Y02_RS22805	COG1879	ABC-type sugar transport system periplasmic component
H1Y02_RS22820	COG2105	PFAM AIG2 family protein
H1Y02_RS22825	COG2911	Protein conserved in bacteria
H1Y02_RS22830	COG0729	surface antigen
H1Y02_RS22840	COG1253	flavin adenine dinucleotide binding
H1Y02_RS22865	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H1Y02_RS22880	COG1733	regulation of RNA biosynthetic process
H1Y02_RS22885	COG0702	epimerase
H1Y02_RS22895	COG0697	spore germination
H1Y02_RS22905	COG1113	amino acid transport
H1Y02_RS22910	COG0545	Peptidyl-prolyl cis-trans isomerase
H1Y02_RS22915	COG3061	Opacity-associated protein A
H1Y02_RS22925	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H1Y02_RS22930	COG2965	DNA replication, synthesis of RNA primer
H1Y02_RS22990	COG1073	alpha beta
H1Y02_RS22995	COG3650	response to hydrogen peroxide
H1Y02_RS23005	COG1960	acyl-CoA dehydrogenase activity
H1Y02_RS23010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1Y02_RS23015	COG0557	exoribonuclease II activity
H1Y02_RS23030	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H1Y02_RS23040	COG0330	HflC and HflK could
H1Y02_RS23045	COG0330	HflC and HflK could
H1Y02_RS23050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1Y02_RS23070	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1Y02_RS23075	COG0802	atpase or kinase
H1Y02_RS23080	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H1Y02_RS23080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1Y02_RS23085	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1Y02_RS23105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Y02_RS23125	COG3264	Mechanosensitive ion channel
H1Y02_RS23125	COG1511	domain protein
H1Y02_RS23140	COG1053	succinate dehydrogenase
H1Y02_RS23145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1Y02_RS23165	COG2076	Multidrug Resistance protein
H1Y02_RS23175	COG5510	response to toxic substance
H1Y02_RS23185	COG1509	lysine 2,3-aminomutase activity
H1Y02_RS23200	COG3121	Chaperone
H1Y02_RS23250	COG0531	amino acid
H1Y02_RS23255	COG3030	protein affecting phage T7 exclusion by the F plasmid
H1Y02_RS23260	COG1027	Aspartate ammonia-lyase
H1Y02_RS23265	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H1Y02_RS23280	COG1309	transcriptional regulator
H1Y02_RS23305	COG0457	Tetratricopeptide repeat
H1Y02_RS23310	COG0726	polysaccharide deacetylase
H1Y02_RS23310	COG1649	PFAM Uncharacterised BCR, COG1649
H1Y02_RS23315	COG1215	transferase activity, transferring glycosyl groups
H1Y02_RS23330	COG0861	Integral membrane protein TerC family
H1Y02_RS23360	COG1486	melibiose metabolic process
H1Y02_RS23365	COG2169	Transcriptional regulator
H1Y02_RS23375	COG2824	Alkylphosphonate utilization operon protein PhnA
H1Y02_RS23380	COG2764	glyoxalase bleomycin resistance protein dioxygenase
H1Y02_RS23385	COG2188	Transcriptional regulator
H1Y02_RS23390	COG3624	Phosphonate C-P lyase system protein PhnG
H1Y02_RS23395	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
H1Y02_RS23400	COG3626	phosphonate metabolism
H1Y02_RS23405	COG3627	carbon phosphorus lyase activity
H1Y02_RS23410	COG4107	phosphonate C-P lyase system protein PhnK
H1Y02_RS23415	COG4778	phosphonate C-P lyase system protein PhnL
H1Y02_RS23420	COG3454	Phosphonate metabolism
H1Y02_RS23430	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H1Y02_RS23440	COG4191	Histidine kinase
H1Y02_RS23440	COG0784	Response regulator, receiver
H1Y02_RS23445	COG1129	ABC transporter
H1Y02_RS23450	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS23475	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H1Y02_RS23480	COG1301	dicarboxylic acid transport
H1Y02_RS23495	COG3162	membrane
H1Y02_RS23520	COG3121	Chaperone
H1Y02_RS23525	COG3539	Fimbrial protein
H1Y02_RS23530	COG1346	cytolysis
H1Y02_RS23535	COG1380	Effector of murein hydrolase LrgA
H1Y02_RS23540	COG0583	DNA-binding transcription factor activity
H1Y02_RS23545	COG0025	NhaP-type Na H and K H
H1Y02_RS23550	COG2252	PERMEase
H1Y02_RS23555	COG0625	glutathione transferase activity
H1Y02_RS23560	COG0789	Transcriptional regulator
H1Y02_RS23570	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H1Y02_RS23595	COG3842	ATPase activity
H1Y02_RS23600	COG1234	tRNA 3'-trailer cleavage
H1Y02_RS23605	COG1609	Transcriptional regulator
H1Y02_RS23610	COG0483	inositol monophosphate 1-phosphatase activity
H1Y02_RS23620	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1Y02_RS23635	COG4771	TonB-dependent receptor
H1Y02_RS23655	COG2315	Protein conserved in bacteria
H1Y02_RS23660	COG0432	Pfam Uncharacterised protein family UPF0047
H1Y02_RS23675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1Y02_RS23680	COG0305	Participates in initiation and elongation during chromosome replication
H1Y02_RS23695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1Y02_RS23705	COG0735	belongs to the Fur family
H1Y02_RS23710	COG3237	CsbD-like
H1Y02_RS23715	COG0534	Mate efflux family protein
H1Y02_RS23725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H1Y02_RS23780	COG3039	Transposase
H1Y02_RS23785	COG3039	Transposase
H1Y02_RS23805	COG0251	oxidation-reduction process
H1Y02_RS23815	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H1Y02_RS23825	COG0527	aspartate kinase activity
H1Y02_RS23885	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1Y02_RS23895	COG0456	acetyltransferase
H1Y02_RS23925	COG0151	Belongs to the GarS family
H1Y02_RS23935	COG4191	Histidine kinase
H1Y02_RS23940	COG3678	ATP-independent chaperone mediated protein folding
H1Y02_RS23975	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
H1Y02_RS23990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H1Y02_RS23995	COG2104	thiamine diphosphate biosynthetic process
H1Y02_RS24005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H1Y02_RS24030	COG5301	cellulose 1,4-beta-cellobiosidase activity
H1Y02_RS24040	COG3039	Transposase
H1Y02_RS24115	COG4397	Mu-like prophage major head subunit gpT
H1Y02_RS24135	COG2369	cell adhesion
H1Y02_RS24140	COG4383	Mu-like prophage protein gp29
H1Y02_RS24190	COG3179	chitinase
H1Y02_RS24220	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
H1Y02_RS24260	COG2842	Transposition protein
H1Y02_RS24270	COG3423	Transcriptional regulator
H1Y02_RS24295	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1Y02_RS24300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H1Y02_RS24335	COG0250	Participates in transcription elongation, termination and antitermination
H1Y02_RS24380	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H1Y02_RS24410	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
H1Y02_RS24420	COG1739	Uncharacterized protein family UPF0029
H1Y02_RS24460	COG0805	protein transport
H1Y02_RS24480	COG3165	ubiquinone biosynthetic process from chorismate
H1Y02_RS24510	COG0583	DNA-binding transcription factor activity
H1Y02_RS24515	COG0697	spore germination
H1Y02_RS24520	COG0561	phosphatase activity
H1Y02_RS24525	COG2267	carboxylic ester hydrolase activity
H1Y02_RS24530	COG1280	lysine exporter protein (LysE YggA)
H1Y02_RS24540	COG1280	lysine exporter protein (LysE YggA)
H1Y02_RS24570	COG0210	DNA helicase
H1Y02_RS24575	COG1011	Hydrolase
H1Y02_RS24605	COG3072	Adenylate cyclase
H1Y02_RS24620	COG2959	enzyme of heme biosynthesis
H1Y02_RS24625	COG3071	HemY protein
H1Y02_RS24670	COG2244	polysaccharide biosynthetic process
H1Y02_RS24675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1Y02_RS24680	COG0456	acetyltransferase
H1Y02_RS24685	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H1Y02_RS24690	COG1088	dTDP-glucose 4,6-dehydratase activity
H1Y02_RS24695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1Y02_RS24700	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H1Y02_RS24710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H1Y02_RS24715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H1Y02_RS24720	COG3118	belongs to the thioredoxin family
H1Y02_RS24740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1Y02_RS24745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1Y02_RS24755	COG0583	DNA-binding transcription factor activity
H1Y02_RS24760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1Y02_RS24775	COG3978	acetolactate synthase activity
H1Y02_RS24795	COG3085	chromosome segregation
H1Y02_RS24870	COG0583	DNA-binding transcription factor activity
H1Y02_RS24885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H1Y02_RS24900	COG3443	Belongs to the bacterial solute-binding protein 9 family
H1Y02_RS24905	COG2207	Transcriptional regulator
H1Y02_RS24915	COG0371	Dehydrogenase
H1Y02_RS24930	COG2190	(PTS) system
H1Y02_RS24930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Y02_RS24930	COG1263	PTS System
H1Y02_RS24935	COG1609	Transcriptional regulator
H1Y02_RS24940	COG0583	DNA-binding transcription factor activity
H1Y02_RS24945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1Y02_RS24950	COG0527	aspartate kinase activity
H1Y02_RS24950	COG0460	homoserine dehydrogenase
H1Y02_RS24955	COG0626	cystathionine gamma-synthase activity
H1Y02_RS24970	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1Y02_RS24975	COG1609	Transcriptional regulator
H1Y02_RS24980	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1Y02_RS24995	COG1575	Belongs to the MenA family. Type 1 subfamily
H1Y02_RS25155	COG4695	Portal protein
H1Y02_RS25200	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H1Y02_RS25250	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1Y02_RS25255	COG3678	ATP-independent chaperone mediated protein folding
H1Y02_RS25260	COG0745	RESPONSE REGULATOR receiver
H1Y02_RS25265	COG2205	protein histidine kinase activity
H1Y02_RS25270	COG2258	MOSC domain
H1Y02_RS25275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1Y02_RS25315	COG1129	ABC transporter
H1Y02_RS25320	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS25330	COG1454	alcohol dehydrogenase
H1Y02_RS25340	COG0110	maltose O-acetyltransferase activity
H1Y02_RS25345	COG2211	Major facilitator Superfamily
H1Y02_RS25405	COG0205	6-phosphofructokinase activity
H1Y02_RS25425	COG0437	4 iron, 4 sulfur cluster binding
H1Y02_RS25430	COG2864	formate dehydrogenase
H1Y02_RS25445	COG0456	acetyltransferase
H1Y02_RS25460	COG1011	Hydrolase
H1Y02_RS25465	COG2271	Major facilitator Superfamily
H1Y02_RS25470	COG1082	Xylose isomerase domain protein TIM barrel
H1Y02_RS25475	COG2188	Transcriptional regulator
H1Y02_RS25490	COG3852	Histidine kinase
H1Y02_RS25505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1Y02_RS25520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1Y02_RS25520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1Y02_RS25525	COG0204	Acyl-transferase
H1Y02_RS25535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1Y02_RS25540	COG3084	Protein conserved in bacteria
H1Y02_RS25550	COG1763	Mo-molybdopterin cofactor biosynthetic process
H1Y02_RS25575	COG2186	Transcriptional regulator
H1Y02_RS25580	COG0477	Major facilitator Superfamily
H1Y02_RS25585	COG1609	Transcriptional regulator
H1Y02_RS25590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1Y02_RS25600	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Y02_RS25605	COG1129	ABC transporter
H1Y02_RS25635	COG1522	sequence-specific DNA binding
H1Y02_RS25640	COG0716	FMN binding
H1Y02_RS25655	COG3312	ion transport
H1Y02_RS25705	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1Y02_RS25710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1Y02_RS25715	COG0573	inorganic phosphate transmembrane transporter activity
H1Y02_RS25720	COG0581	inorganic phosphate transmembrane transporter activity
H1Y02_RS25725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1Y02_RS25730	COG0704	Plays a role in the regulation of phosphate uptake
H1Y02_RS25740	COG2382	esterase
H1Y02_RS25745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1Y02_RS25750	COG2252	PERMEase
H1Y02_RS25755	COG0431	NADPH-dependent FMN reductase
H1Y02_RS25760	COG2091	lysine biosynthetic process via aminoadipic acid
H1Y02_RS25790	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H1Y02_RS25830	COG3344	reverse transcriptase
H1Y02_RS25860	COG3039	Transposase
H1Y02_RS25870	COG3039	Transposase
H1Y02_RS25910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1Y02_RS26145	COG1192	Involved in chromosome partitioning
H1Y02_RS26285	COG1401	restriction endodeoxyribonuclease activity
H1Y02_RS26285	COG1401	restriction endodeoxyribonuclease activity
H1Y02_RS26300	COG2801	Transposase and inactivated derivatives
H1Y02_RS26310	COG2801	Transposase and inactivated derivatives
H1Y02_RS26360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1Y02_RS26365	COG0501	Belongs to the peptidase M48B family
H1Y02_RS26880	COG2801	Transposase and inactivated derivatives
H1Y02_RS26900	COG0033	Phosphoglucomutase
H1Y02_RS26905	COG0058	SHG alpha-glucan phosphorylase activity
H1Y02_RS26955	COG0732	type I restriction modification DNA specificity domain
H1Y02_RS27005	COG5642	Protein of unknown function (DUF2384)
H1Y02_RS27025	COG4974	Belongs to the 'phage' integrase family
H1Y02_RS27080	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H1Y02_RS27185	COG5001	Diguanylate cyclase
H1Y02_RS27185	COG3300	MHYT domain
H1Y02_RS27225	COG4644	lycopene metabolic process
H1Y02_RS27250	COG5433	transposase activity
H1Y02_RS27360	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
H1Y02_RS27615	COG1475	DNA binding
H1Y02_RS27850	COG1475	DNA binding
H1Y02_RS27880	COG5499	transcription regulator containing HTH domain