locus-tag	class	description
HUR98_RS00020	COG0187	DNA topoisomerase II activity
HUR98_RS00025	COG0561	phosphatase activity
HUR98_RS00040	COG2186	Transcriptional regulator
HUR98_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
HUR98_RS00050	COG0800	Aldolase
HUR98_RS00070	COG2271	Major facilitator Superfamily
HUR98_RS00075	COG0823	Involved in the tonB-independent uptake of proteins
HUR98_RS00080	COG5645	(Lipo)protein
HUR98_RS00095	COG3645	SOS response
HUR98_RS00105	COG2188	Transcriptional regulator
HUR98_RS00120	COG2149	membrane
HUR98_RS00140	COG2610	gluconate transmembrane transporter activity
HUR98_RS00150	COG0583	DNA-binding transcription factor activity
HUR98_RS00155	COG2814	Major facilitator Superfamily
HUR98_RS00185	COG0028	Belongs to the TPP enzyme family
HUR98_RS00190	COG0440	acetolactate synthase activity
HUR98_RS00195	COG2197	response regulator
HUR98_RS00205	COG2271	Major facilitator Superfamily
HUR98_RS00245	COG2188	Transcriptional regulator
HUR98_RS00270	COG4580	involved in the transport of maltose and maltodextrins
HUR98_RS00275	COG1447	Phosphotransferase system cellobiose-specific component IIA
HUR98_RS00280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS00280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS00290	COG1609	Transcriptional regulator
HUR98_RS00300	COG3384	dioxygenase
HUR98_RS00305	COG0583	DNA-binding transcription factor activity
HUR98_RS00310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUR98_RS00315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUR98_RS00320	COG2828	Protein conserved in bacteria
HUR98_RS00335	COG0697	spore germination
HUR98_RS00340	COG1263	PTS System
HUR98_RS00340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUR98_RS00350	COG2814	Major facilitator Superfamily
HUR98_RS00360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUR98_RS00395	COG0583	DNA-binding transcription factor activity
HUR98_RS00420	COG1464	Belongs to the NlpA lipoprotein family
HUR98_RS00435	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUR98_RS00445	COG1064	alcohol dehydrogenase
HUR98_RS00475	COG2211	Major facilitator Superfamily
HUR98_RS00480	COG1501	Belongs to the glycosyl hydrolase 31 family
HUR98_RS00490	COG1486	melibiose metabolic process
HUR98_RS00495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUR98_RS00495	COG1263	PTS System
HUR98_RS00500	COG2982	Protein involved in outer membrane biogenesis
HUR98_RS00505	COG2233	PERMEase
HUR98_RS00510	COG0786	glutamate:sodium symporter activity
HUR98_RS00530	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HUR98_RS00555	COG3152	Membrane
HUR98_RS00565	COG1494	fructose-1,6-bisphosphatase
HUR98_RS00570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUR98_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUR98_RS00580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUR98_RS00600	COG2860	membrane
HUR98_RS00610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUR98_RS00610	COG2169	Transcriptional regulator
HUR98_RS00615	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HUR98_RS00620	COG1561	YicC-like family, N-terminal region
HUR98_RS00625	COG3039	Transposase
HUR98_RS00645	COG1131	(ABC) transporter
HUR98_RS00650	COG0842	Transport permease protein
HUR98_RS00675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HUR98_RS00710	COG1519	Transferase
HUR98_RS00715	COG1216	Glycosyl transferase, family 2
HUR98_RS00720	COG0438	transferase activity, transferring glycosyl groups
HUR98_RS00730	COG0859	PFAM glycosyl transferase family 9
HUR98_RS00755	COG0859	PFAM glycosyl transferase family 9
HUR98_RS00770	COG0156	8-amino-7-oxononanoate synthase activity
HUR98_RS00780	COG0463	Glycosyl transferase, family 2
HUR98_RS00785	COG2861	carbohydrate metabolic process
HUR98_RS00790	COG4942	peptidase
HUR98_RS00800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUR98_RS00805	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HUR98_RS00825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUR98_RS00835	COG2186	Transcriptional regulator
HUR98_RS00855	COG3722	fumarate hydratase activity
HUR98_RS00875	COG1566	PFAM secretion protein HlyD family protein
HUR98_RS00880	COG0625	glutathione transferase activity
HUR98_RS00890	COG3276	selenocysteine insertion sequence binding
HUR98_RS00895	COG1414	Transcriptional regulator
HUR98_RS00900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUR98_RS00905	COG3977	Valine--pyruvate aminotransferase
HUR98_RS00910	COG0366	Alpha amylase catalytic
HUR98_RS00915	COG2992	FlgJ-related protein
HUR98_RS00920	COG2207	Transcriptional regulator
HUR98_RS00920	COG1609	Transcriptional regulator
HUR98_RS00925	COG4214	carbohydrate transport
HUR98_RS00935	COG4213	ABC transporter substrate-binding protein
HUR98_RS00950	COG4682	membrane
HUR98_RS00955	COG4682	membrane
HUR98_RS00960	COG3274	enterobacterial common antigen metabolic process
HUR98_RS00995	COG1278	Cold shock
HUR98_RS01000	COG2944	sequence-specific DNA binding
HUR98_RS01005	COG2814	Major facilitator Superfamily
HUR98_RS01025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUR98_RS01035	COG1609	Transcriptional regulator
HUR98_RS01040	COG2885	chlorophyll binding
HUR98_RS01045	COG0243	molybdopterin cofactor binding
HUR98_RS01050	COG0456	acetyltransferase
HUR98_RS01055	COG2818	Glycosylase
HUR98_RS01060	COG5571	outer membrane autotransporter
HUR98_RS01065	COG2223	nitrite transmembrane transporter activity
HUR98_RS01095	COG0747	negative chemotaxis
HUR98_RS01100	COG0601	transmembrane transport
HUR98_RS01105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUR98_RS01110	COG0444	Belongs to the ABC transporter superfamily
HUR98_RS01115	COG4608	Belongs to the ABC transporter superfamily
HUR98_RS01140	COG1215	transferase activity, transferring glycosyl groups
HUR98_RS01145	COG0457	Tetratricopeptide repeat
HUR98_RS01160	COG2194	sulfuric ester hydrolase activity
HUR98_RS01190	COG1215	transferase activity, transferring glycosyl groups
HUR98_RS01195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HUR98_RS01200	COG0457	Tetratricopeptide repeat
HUR98_RS01200	COG3118	belongs to the thioredoxin family
HUR98_RS01205	COG2200	EAL domain
HUR98_RS01205	COG2199	diguanylate cyclase activity
HUR98_RS01215	COG0612	Peptidase, M16
HUR98_RS01225	COG2982	Protein involved in outer membrane biogenesis
HUR98_RS01230	COG0477	Major facilitator Superfamily
HUR98_RS01235	COG1295	ribonuclease BN
HUR98_RS01240	COG0583	DNA-binding transcription factor activity
HUR98_RS01245	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS01250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUR98_RS01260	COG1454	alcohol dehydrogenase
HUR98_RS01270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUR98_RS01275	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HUR98_RS01280	COG0671	phosphoesterase, PA-phosphatase related
HUR98_RS01300	COG0589	response to stress
HUR98_RS01310	COG0306	phosphate transporter
HUR98_RS01315	COG2081	HI0933 family
HUR98_RS01320	COG2239	Acts as a magnesium transporter
HUR98_RS01330	COG1124	(ABC) transporter
HUR98_RS01340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUR98_RS01345	COG0601	transmembrane transport
HUR98_RS01350	COG0747	negative chemotaxis
HUR98_RS01360	COG3479	Phenolic acid decarboxylase
HUR98_RS01400	COG0628	permease
HUR98_RS01405	COG0477	Major facilitator Superfamily
HUR98_RS01415	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HUR98_RS01430	COG3714	YhhN family
HUR98_RS01440	COG3776	membrane
HUR98_RS01445	COG0742	ribosomal rna small subunit methyltransferase
HUR98_RS01450	COG0552	protein localization to endoplasmic reticulum
HUR98_RS01455	COG2884	Cell division ATP-binding protein ftsE
HUR98_RS01460	COG2177	Part of the ABC transporter FtsEX involved in
HUR98_RS01475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUR98_RS01485	COG0683	leucine binding
HUR98_RS01495	COG0683	leucine binding
HUR98_RS01500	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS01550	COG0584	glycerophosphoryl diester phosphodiesterase
HUR98_RS01560	COG0405	Gamma-glutamyltransferase
HUR98_RS01565	COG1247	-acetyltransferase
HUR98_RS01575	COG0673	inositol 2-dehydrogenase activity
HUR98_RS01580	COG1741	Belongs to the pirin family
HUR98_RS01585	COG1609	Transcriptional regulator
HUR98_RS01590	COG3265	gluconokinase activity
HUR98_RS01595	COG2610	gluconate transmembrane transporter activity
HUR98_RS01605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUR98_RS01630	COG0058	SHG alpha-glucan phosphorylase activity
HUR98_RS01645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUR98_RS01660	COG1349	DNA-binding transcription factor activity
HUR98_RS01670	COG0058	SHG alpha-glucan phosphorylase activity
HUR98_RS01675	COG1640	4-alpha-glucanotransferase
HUR98_RS01680	COG2610	gluconate transmembrane transporter activity
HUR98_RS01690	COG1040	competence protein
HUR98_RS01715	COG1918	ferrous iron import across plasma membrane
HUR98_RS01720	COG2183	response to ionizing radiation
HUR98_RS01725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUR98_RS01730	COG0745	RESPONSE REGULATOR receiver
HUR98_RS01750	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HUR98_RS01755	COG1011	Hydrolase
HUR98_RS01765	COG0494	nUDIX hydrolase
HUR98_RS01770	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUR98_RS01795	COG4796	Type ii and iii secretion system protein
HUR98_RS01810	COG3266	domain, Protein
HUR98_RS01815	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HUR98_RS01820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUR98_RS01845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUR98_RS01850	COG0402	S-adenosylhomocysteine deaminase activity
HUR98_RS01855	COG0738	Major facilitator superfamily
HUR98_RS01880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUR98_RS01885	COG1289	transmembrane transporter activity
HUR98_RS01895	COG1765	OsmC-like protein
HUR98_RS01900	COG3954	Phosphoribulokinase
HUR98_RS01910	COG0429	hydrolase of the alpha beta-hydrolase fold
HUR98_RS01915	COG0488	(ABC) transporter
HUR98_RS01930	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HUR98_RS01935	COG1047	Peptidyl-prolyl cis-trans
HUR98_RS01945	COG0545	Peptidyl-prolyl cis-trans isomerase
HUR98_RS01950	COG2964	Protein conserved in bacteria
HUR98_RS02005	COG0051	transcription antitermination factor activity, RNA binding
HUR98_RS02030	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUR98_RS02045	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUR98_RS02110	COG0201	protein transport
HUR98_RS02135	COG0202	RNA polymerase activity
HUR98_RS02150	COG0789	Transcriptional regulator
HUR98_RS02155	COG3036	rescue of stalled ribosome
HUR98_RS02185	COG0758	DNA mediated transformation
HUR98_RS02195	COG0551	DNA topoisomerase type I activity
HUR98_RS02215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUR98_RS02250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUR98_RS02255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUR98_RS02260	COG1309	transcriptional regulator
HUR98_RS02265	COG0582	viral genome integration into host DNA
HUR98_RS02280	COG3561	AntA/AntB antirepressor
HUR98_RS02365	COG1802	Transcriptional regulator
HUR98_RS02365	COG4626	Terminase
HUR98_RS02390	COG4145	pantothenate transmembrane transporter activity
HUR98_RS02395	COG3924	membrane
HUR98_RS02400	COG0439	Biotin carboxylase
HUR98_RS02405	COG0511	ligase activity, forming carbon-carbon bonds
HUR98_RS02430	COG2199	diguanylate cyclase activity
HUR98_RS02430	COG2200	EAL domain
HUR98_RS02435	COG1077	Cell shape determining protein MreB Mrl
HUR98_RS02440	COG1792	Involved in formation and maintenance of cell shape
HUR98_RS02445	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HUR98_RS02455	COG1530	ribonuclease E activity
HUR98_RS02460	COG3164	Protein of unknown function
HUR98_RS02465	COG0312	modulator of DNA gyrase
HUR98_RS02470	COG0583	DNA-binding transcription factor activity
HUR98_RS02485	COG1289	transmembrane transporter activity
HUR98_RS02490	COG2732	(Barnase) inhibitor
HUR98_RS02515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUR98_RS02520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUR98_RS02525	COG3105	Protein conserved in bacteria
HUR98_RS02530	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HUR98_RS02550	COG0625	glutathione transferase activity
HUR98_RS02555	COG2969	positive regulation of protein catabolic process
HUR98_RS02565	COG0493	'glutamate synthase
HUR98_RS02570	COG0070	glutamate synthase
HUR98_RS02570	COG0069	glutamate synthase activity
HUR98_RS02570	COG0067	glutamate synthase
HUR98_RS02575	COG1242	4 iron, 4 sulfur cluster binding
HUR98_RS02580	COG2271	Major facilitator Superfamily
HUR98_RS02585	COG3039	Transposase
HUR98_RS02590	COG1063	alcohol dehydrogenase
HUR98_RS02595	COG1312	Catalyzes the dehydration of D-mannonate
HUR98_RS02600	COG0784	Response regulator, receiver
HUR98_RS02600	COG2198	Histidine kinase
HUR98_RS02600	COG5002	protein histidine kinase activity
HUR98_RS02605	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HUR98_RS02610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUR98_RS02615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS02625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS02630	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUR98_RS02635	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HUR98_RS02640	COG1137	ATPase activity
HUR98_RS02645	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HUR98_RS02650	COG3117	lipopolysaccharide transmembrane transporter activity
HUR98_RS02655	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HUR98_RS02665	COG0530	calcium, potassium:sodium antiporter activity
HUR98_RS02670	COG1127	ABC transporter
HUR98_RS02675	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUR98_RS02680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUR98_RS02685	COG2854	intermembrane phospholipid transfer
HUR98_RS02690	COG3113	response to antibiotic
HUR98_RS02695	COG5007	Belongs to the BolA IbaG family
HUR98_RS02705	COG3423	Transcriptional regulator
HUR98_RS02710	COG0142	geranyltranstransferase activity
HUR98_RS02725	COG0697	spore germination
HUR98_RS02735	COG2027	D-alanyl-D-alanine carboxypeptidase
HUR98_RS02745	COG1534	Rna-binding protein
HUR98_RS02755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUR98_RS02760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUR98_RS02770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUR98_RS02810	COG0195	Participates in both transcription termination and antitermination
HUR98_RS02855	COG0814	amino acid
HUR98_RS02860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUR98_RS02865	COG0826	peptidase U32
HUR98_RS02870	COG0826	peptidase U32
HUR98_RS02875	COG3154	lipid carrier protein
HUR98_RS02880	COG3153	acetyltransferase
HUR98_RS02895	COG0693	protein deglycase activity
HUR98_RS02900	COG0702	epimerase
HUR98_RS02905	COG0701	Predicted permease
HUR98_RS02910	COG2823	Periplasmic or secreted lipoprotein
HUR98_RS02930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HUR98_RS02945	COG1063	alcohol dehydrogenase
HUR98_RS02950	COG3775	system Galactitol-specific IIC component
HUR98_RS02955	COG3414	Phosphotransferase system galactitol-specific IIB component
HUR98_RS02960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS02970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS02970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS02975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUR98_RS02975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS02975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUR98_RS02980	COG1105	Belongs to the carbohydrate kinase PfkB family
HUR98_RS02990	COG1349	DNA-binding transcription factor activity
HUR98_RS02995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUR98_RS03000	COG2721	sulfolactate sulfo-lyase activity
HUR98_RS03005	COG2271	Major facilitator Superfamily
HUR98_RS03015	COG2084	Dehydrogenase
HUR98_RS03020	COG1929	Belongs to the glycerate kinase type-1 family
HUR98_RS03045	COG1741	Belongs to the pirin family
HUR98_RS03050	COG0583	DNA-binding transcription factor activity
HUR98_RS03055	COG3152	Membrane
HUR98_RS03060	COG0435	Glutathione S-transferase
HUR98_RS03065	COG2259	Doxx family
HUR98_RS03075	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HUR98_RS03080	COG4575	ribosome binding
HUR98_RS03085	COG1422	Protein of unknown function (DUF1090)
HUR98_RS03095	COG0586	Pfam SNARE associated Golgi protein
HUR98_RS03100	COG2186	Transcriptional regulator
HUR98_RS03105	COG2271	Major facilitator Superfamily
HUR98_RS03115	COG2721	sulfolactate sulfo-lyase activity
HUR98_RS03130	COG0861	Integral membrane protein TerC family
HUR98_RS03135	COG0673	inositol 2-dehydrogenase activity
HUR98_RS03140	COG1451	nucleotide metabolic process
HUR98_RS03160	COG1902	pentaerythritol trinitrate reductase activity
HUR98_RS03160	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUR98_RS03215	COG1695	Transcriptional regulator
HUR98_RS03220	COG2375	cellular response to nickel ion
HUR98_RS03235	COG1461	Dihydroxyacetone kinase
HUR98_RS03240	COG2376	Dihydroxyacetone kinase
HUR98_RS03310	COG3247	response to pH
HUR98_RS03320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUR98_RS03320	COG2198	Histidine kinase
HUR98_RS03320	COG2205	protein histidine kinase activity
HUR98_RS03320	COG0784	Response regulator, receiver
HUR98_RS03325	COG2197	response regulator
HUR98_RS03350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUR98_RS03355	COG0358	DNA primase activity
HUR98_RS03360	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HUR98_RS03430	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUR98_RS03445	COG4991	sh3 domain protein
HUR98_RS03450	COG3025	triphosphatase activity
HUR98_RS03475	COG2960	long-chain fatty acid transporting porin activity
HUR98_RS03490	COG3384	dioxygenase
HUR98_RS03495	COG0754	glutathionylspermidine amidase activity
HUR98_RS03510	COG0494	nUDIX hydrolase
HUR98_RS03515	COG3151	Protein conserved in bacteria
HUR98_RS03520	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUR98_RS03525	COG3150	esterase
HUR98_RS03535	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HUR98_RS03540	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUR98_RS03545	COG0642	Histidine kinase
HUR98_RS03555	COG3111	PFAM Bacterial OB fold (BOF) protein
HUR98_RS03560	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HUR98_RS03565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUR98_RS03570	COG0204	Acyl-transferase
HUR98_RS03575	COG2132	Multicopper oxidase
HUR98_RS03580	COG1032	radical SAM domain protein
HUR98_RS03590	COG0656	L-ascorbic acid biosynthetic process
HUR98_RS03595	COG1979	alcohol dehydrogenase
HUR98_RS03600	COG2207	Transcriptional regulator
HUR98_RS03605	COG0586	Pfam SNARE associated Golgi protein
HUR98_RS03610	COG0626	cystathionine gamma-synthase activity
HUR98_RS03620	COG0848	biopolymer transport protein
HUR98_RS03625	COG2211	Major facilitator Superfamily
HUR98_RS03650	COG0625	glutathione transferase activity
HUR98_RS03665	COG0754	glutathionylspermidine amidase activity
HUR98_RS03670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUR98_RS03690	COG0583	DNA-binding transcription factor activity
HUR98_RS03695	COG0626	cystathionine gamma-synthase activity
HUR98_RS03910	COG3039	Transposase
HUR98_RS03960	COG3423	Transcriptional regulator
HUR98_RS03970	COG1278	Cold shock
HUR98_RS03975	COG3423	Transcriptional regulator
HUR98_RS04045	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HUR98_RS04055	COG1811	Na channel or pump
HUR98_RS04060	COG1982	Orn Lys Arg decarboxylase major
HUR98_RS04065	COG2211	Major facilitator Superfamily
HUR98_RS04080	COG1194	a g-specific adenine glycosylase
HUR98_RS04090	COG3171	Protein conserved in bacteria
HUR98_RS04100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUR98_RS04115	COG0762	integral membrane protein
HUR98_RS04120	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUR98_RS04125	COG2805	Type II/IV secretion system protein
HUR98_RS04145	COG0189	ligase activity
HUR98_RS04150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HUR98_RS04155	COG2356	endonuclease I
HUR98_RS04165	COG2814	Major facilitator Superfamily
HUR98_RS04200	COG2146	nitrite reductase [NAD(P)H] activity
HUR98_RS04215	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS04220	COG1414	Transcriptional regulator
HUR98_RS04250	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS04255	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HUR98_RS04280	COG0501	Belongs to the peptidase M48B family
HUR98_RS04285	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUR98_RS04300	COG0191	fructose-bisphosphate aldolase activity
HUR98_RS04305	COG0668	transmembrane transport
HUR98_RS04315	COG2968	Membrane
HUR98_RS04330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUR98_RS04335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUR98_RS04355	COG0006	proline dipeptidase activity
HUR98_RS04360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUR98_RS04365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUR98_RS04385	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS04390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUR98_RS04410	COG2723	6-phospho-beta-galactosidase activity
HUR98_RS04415	COG1737	Transcriptional regulator
HUR98_RS04425	COG1272	protein, Hemolysin III
HUR98_RS04435	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HUR98_RS04445	COG0716	FMN binding
HUR98_RS04450	COG4974	Belongs to the 'phage' integrase family
HUR98_RS04460	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HUR98_RS04480	COG4942	peptidase
HUR98_RS04490	COG2814	Major facilitator Superfamily
HUR98_RS04505	COG0667	Aldo Keto reductase
HUR98_RS04540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HUR98_RS04545	COG1393	Belongs to the ArsC family
HUR98_RS04550	COG3104	oligopeptide transport
HUR98_RS04560	COG1538	Outer membrane efflux protein
HUR98_RS04565	COG1289	transmembrane transporter activity
HUR98_RS04580	COG3592	Divergent 4Fe-4S mono-cluster
HUR98_RS04585	COG2388	GCN5-related N-acetyl-transferase
HUR98_RS04595	COG3539	Fimbrial protein
HUR98_RS04600	COG3539	Fimbrial protein
HUR98_RS04605	COG3539	Fimbrial protein
HUR98_RS04610	COG3188	usher protein
HUR98_RS04615	COG3121	Chaperone
HUR98_RS04620	COG3539	Fimbrial protein
HUR98_RS04630	COG4974	Belongs to the 'phage' integrase family
HUR98_RS04635	COG0582	viral genome integration into host DNA
HUR98_RS04640	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HUR98_RS04645	COG1846	Transcriptional regulator
HUR98_RS04650	COG0697	spore germination
HUR98_RS04700	COG0667	Aldo Keto reductase
HUR98_RS04705	COG0814	amino acid
HUR98_RS04720	COG0183	Belongs to the thiolase family
HUR98_RS04730	COG0823	Involved in the tonB-independent uptake of proteins
HUR98_RS04735	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS04740	COG2814	Major facilitator Superfamily
HUR98_RS04775	COG3842	ATPase activity
HUR98_RS04780	COG0395	ABC-type sugar transport system, permease component
HUR98_RS04785	COG1175	transmembrane transport
HUR98_RS04790	COG1917	Cupin 2, conserved barrel domain protein
HUR98_RS04795	COG1794	racemase activity, acting on amino acids and derivatives
HUR98_RS04800	COG0583	DNA-binding transcription factor activity
HUR98_RS04810	COG1609	Transcriptional regulator
HUR98_RS04815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS04820	COG2723	6-phospho-beta-galactosidase activity
HUR98_RS04825	COG2186	Transcriptional regulator
HUR98_RS04835	COG1609	Transcriptional regulator
HUR98_RS04850	COG0667	Aldo Keto reductase
HUR98_RS04860	COG0861	Integral membrane protein TerC family
HUR98_RS04895	COG2165	general secretion pathway protein
HUR98_RS04900	COG4795	General secretion pathway protein
HUR98_RS04910	COG4967	type IV pilus modification protein PilV
HUR98_RS04915	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HUR98_RS04920	COG1025	Belongs to the peptidase M16 family
HUR98_RS04925	COG1074	ATP-dependent DNA helicase activity
HUR98_RS04930	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUR98_RS04940	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUR98_RS04940	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUR98_RS04945	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUR98_RS04950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUR98_RS04980	COG4656	Part of a membrane complex involved in electron transport
HUR98_RS04985	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS04985	COG1454	alcohol dehydrogenase
HUR98_RS05180	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HUR98_RS05185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HUR98_RS05190	COG2166	iron-sulfur cluster assembly
HUR98_RS05195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUR98_RS05205	COG0583	DNA-binding transcription factor activity
HUR98_RS05210	COG2363	Small membrane protein
HUR98_RS05220	COG1349	DNA-binding transcription factor activity
HUR98_RS05240	COG0738	Major facilitator superfamily
HUR98_RS05245	COG0235	Class ii aldolase
HUR98_RS05250	COG1454	alcohol dehydrogenase
HUR98_RS05270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUR98_RS05285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUR98_RS05290	COG2011	ABC-type metal ion transport system permease component
HUR98_RS05295	COG1464	Belongs to the NlpA lipoprotein family
HUR98_RS05300	COG0477	Major facilitator Superfamily
HUR98_RS05310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUR98_RS05315	COG1760	l-serine dehydratase
HUR98_RS05320	COG0814	amino acid
HUR98_RS05325	COG1611	Belongs to the LOG family
HUR98_RS05340	COG3098	single-species biofilm formation
HUR98_RS05345	COG0564	pseudouridine synthase activity
HUR98_RS05350	COG0716	FMN binding
HUR98_RS05355	COG2271	Major facilitator Superfamily
HUR98_RS05360	COG4948	Mandelate Racemase Muconate Lactonizing
HUR98_RS05365	COG4948	Mandelate Racemase Muconate Lactonizing
HUR98_RS05370	COG1929	Belongs to the glycerate kinase type-1 family
HUR98_RS05375	COG3437	response regulator, receiver
HUR98_RS05375	COG3850	Histidine kinase
HUR98_RS05375	COG4999	Histidine kinase
HUR98_RS05375	COG2205	protein histidine kinase activity
HUR98_RS05385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUR98_RS05390	COG3956	TIGRFAM MazG family protein
HUR98_RS05410	COG0602	queuosine metabolic process
HUR98_RS05415	COG0720	synthase
HUR98_RS05435	COG2234	aminopeptidase activity
HUR98_RS05495	COG4942	peptidase
HUR98_RS05495	COG1388	LysM domain
HUR98_RS05500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUR98_RS05525	COG0163	prenyltransferase activity
HUR98_RS05530	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HUR98_RS05570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUR98_RS05575	COG4558	Periplasmic binding protein
HUR98_RS05580	COG3720	iron ion transport
HUR98_RS05600	COG0679	Auxin Efflux Carrier
HUR98_RS05615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUR98_RS05620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUR98_RS05625	COG1121	(ABC) transporter
HUR98_RS05630	COG0803	Belongs to the bacterial solute-binding protein 9 family
HUR98_RS05635	COG1609	Transcriptional regulator
HUR98_RS05640	COG1940	carbohydrate kinase activity
HUR98_RS05645	COG1447	Phosphotransferase system cellobiose-specific component IIA
HUR98_RS05650	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS05655	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS05660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS05665	COG4580	involved in the transport of maltose and maltodextrins
HUR98_RS05675	COG2723	6-phospho-beta-galactosidase activity
HUR98_RS05685	COG0309	Hydrogenase expression formation protein (HypE)
HUR98_RS05690	COG0409	Hydrogenase expression formation protein
HUR98_RS05695	COG0298	carbon dioxide binding
HUR98_RS05700	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUR98_RS05715	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUR98_RS05720	COG0651	ATP synthesis coupled electron transport
HUR98_RS05725	COG0650	Formate hydrogenlyase subunit 4
HUR98_RS05730	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HUR98_RS05730	COG3261	NADH dehydrogenase
HUR98_RS05735	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUR98_RS05740	COG3260	NADH ubiquinone oxidoreductase 20
HUR98_RS05750	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HUR98_RS05760	COG2723	6-phospho-beta-galactosidase activity
HUR98_RS05765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUR98_RS05765	COG1263	PTS System
HUR98_RS05770	COG1609	Transcriptional regulator
HUR98_RS05775	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUR98_RS05780	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HUR98_RS05785	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HUR98_RS05810	COG1349	DNA-binding transcription factor activity
HUR98_RS05815	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS05820	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS05830	COG3732	PTS system glucitol sorbitol-specific
HUR98_RS05835	COG3730	PTS system glucitol sorbitol-specific
HUR98_RS05840	COG2951	lytic endotransglycosylase activity
HUR98_RS05845	COG1121	(ABC) transporter
HUR98_RS05850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUR98_RS05860	COG1546	Belongs to the CinA family
HUR98_RS05880	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HUR98_RS05910	COG2823	Periplasmic or secreted lipoprotein
HUR98_RS05915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUR98_RS05920	COG1238	metal cluster binding
HUR98_RS05940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUR98_RS05945	COG2814	Major facilitator Superfamily
HUR98_RS05950	COG1566	PFAM secretion protein HlyD family protein
HUR98_RS05955	COG1846	Transcriptional regulator
HUR98_RS05965	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HUR98_RS05975	COG4176	ABC-type proline glycine betaine transport system permease component
HUR98_RS05990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUR98_RS06000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HUR98_RS06005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUR98_RS06010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUR98_RS06015	COG4575	ribosome binding
HUR98_RS06030	COG2916	Histone family protein nucleoid-structuring protein H-NS
HUR98_RS06045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUR98_RS06050	COG0640	Transcriptional regulator
HUR98_RS06060	COG0583	DNA-binding transcription factor activity
HUR98_RS06065	COG3284	Transcriptional regulator
HUR98_RS06070	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS06080	COG4974	Belongs to the 'phage' integrase family
HUR98_RS06115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUR98_RS06130	COG3344	reverse transcriptase
HUR98_RS06165	COG4695	Portal protein
HUR98_RS06335	COG2867	negative regulation of translational initiation
HUR98_RS06350	COG0497	DNA recombination
HUR98_RS06365	COG4536	flavin adenine dinucleotide binding
HUR98_RS06370	COG4137	Cytochrome C assembly protein
HUR98_RS06375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HUR98_RS06410	COG2885	chlorophyll binding
HUR98_RS06415	COG2199	diguanylate cyclase activity
HUR98_RS06425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUR98_RS06430	COG0287	Prephenate dehydrogenase
HUR98_RS06430	COG1605	Chorismate mutase
HUR98_RS06440	COG0077	Prephenate dehydratase
HUR98_RS06440	COG1605	Chorismate mutase
HUR98_RS06450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUR98_RS06455	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUR98_RS06470	COG0542	response to heat
HUR98_RS06495	COG0477	Major facilitator Superfamily
HUR98_RS06500	COG5544	Lipoprotein
HUR98_RS06505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUR98_RS06520	COG3118	belongs to the thioredoxin family
HUR98_RS06525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUR98_RS06540	COG0513	Belongs to the DEAD box helicase family
HUR98_RS06550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUR98_RS06565	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HUR98_RS06570	COG3026	antisigma factor binding
HUR98_RS06575	COG3086	response to oxidative stress
HUR98_RS06585	COG0681	Belongs to the peptidase S26 family
HUR98_RS06605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HUR98_RS06615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUR98_RS06620	COG1737	Transcriptional regulator
HUR98_RS06625	COG0560	Phosphoserine phosphatase
HUR98_RS06640	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUR98_RS06640	COG0047	phosphoribosylformylglycinamidine synthase activity
HUR98_RS06645	COG2205	protein histidine kinase activity
HUR98_RS06650	COG3170	Tfp pilus assembly protein FimV
HUR98_RS06655	COG2204	response regulator
HUR98_RS06660	COG0347	Belongs to the P(II) protein family
HUR98_RS06665	COG1017	nitric oxide dioxygenase activity
HUR98_RS06665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUR98_RS06675	COG2259	Doxx family
HUR98_RS06680	COG1940	carbohydrate kinase activity
HUR98_RS06685	COG0457	Tetratricopeptide repeat
HUR98_RS06690	COG2814	Major facilitator Superfamily
HUR98_RS06690	COG0477	Major facilitator Superfamily
HUR98_RS06695	COG2017	converts alpha-aldose to the beta-anomer
HUR98_RS06700	COG2814	Major facilitator Superfamily
HUR98_RS06705	COG3711	transcriptional antiterminator
HUR98_RS06710	COG3683	transport system, periplasmic component
HUR98_RS06715	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HUR98_RS06750	COG0822	iron-sulfur transferase activity
HUR98_RS06770	COG0633	Ferredoxin
HUR98_RS06775	COG2975	iron-sulfur cluster assembly
HUR98_RS06795	COG2897	thiosulfate sulfurtransferase activity
HUR98_RS06800	COG2373	Large extracellular alpha-helical protein
HUR98_RS06805	COG4953	penicillin-binding protein 1C
HUR98_RS06835	COG2976	Protein conserved in bacteria
HUR98_RS06855	COG1645	bacterial-type flagellum-dependent swarming motility
HUR98_RS06865	COG0517	IMP dehydrogenase activity
HUR98_RS06865	COG0516	GMP reductase activity
HUR98_RS06915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUR98_RS07005	COG5484	DNA packaging
HUR98_RS07005	COG3728	DNA packaging
HUR98_RS07105	COG3617	BRO family, N-terminal domain
HUR98_RS07135	COG3179	chitinase
HUR98_RS07145	COG3119	arylsulfatase activity
HUR98_RS07150	COG0641	radical SAM
HUR98_RS07170	COG2200	EAL domain
HUR98_RS07185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HUR98_RS07200	COG2723	6-phospho-beta-galactosidase activity
HUR98_RS07210	COG2233	PERMEase
HUR98_RS07225	COG1393	Belongs to the ArsC family
HUR98_RS07230	COG4783	chaperone-mediated protein folding
HUR98_RS07240	COG0628	permease
HUR98_RS07245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUR98_RS07250	COG2716	regulation of RNA biosynthetic process
HUR98_RS07260	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HUR98_RS07270	COG2321	neutral zinc metallopeptidase
HUR98_RS07275	COG1444	tRNA N-acetyltransferase activity
HUR98_RS07280	COG0400	carboxylic ester hydrolase activity
HUR98_RS07295	COG1393	Belongs to the ArsC family
HUR98_RS07305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUR98_RS07310	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUR98_RS07310	COG0493	'glutamate synthase
HUR98_RS07320	COG5342	invasion associated locus B
HUR98_RS07325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUR98_RS07330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUR98_RS07340	COG4810	utilization protein
HUR98_RS07430	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUR98_RS07450	COG2837	iron assimilation
HUR98_RS07460	COG4150	thiosulfate binding
HUR98_RS07465	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HUR98_RS07470	COG4208	sulfate ABC transporter
HUR98_RS07475	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HUR98_RS07485	COG4319	ketosteroid isomerase
HUR98_RS07520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUR98_RS07540	COG3530	Putative quorum-sensing-regulated virulence factor
HUR98_RS07545	COG0385	Bile acid
HUR98_RS07550	COG0583	DNA-binding transcription factor activity
HUR98_RS07580	COG3415	Transposase
HUR98_RS07585	COG3415	Transposase
HUR98_RS07600	COG2199	diguanylate cyclase activity
HUR98_RS07600	COG2200	EAL domain
HUR98_RS07605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUR98_RS07620	COG0667	Aldo Keto reductase
HUR98_RS07625	COG3961	Belongs to the TPP enzyme family
HUR98_RS07640	COG3279	Response regulator of the LytR AlgR family
HUR98_RS07645	COG3275	phosphorelay sensor kinase activity
HUR98_RS07660	COG0436	Aminotransferase
HUR98_RS07670	COG2807	transmembrane transport
HUR98_RS07675	COG0590	tRNA wobble adenosine to inosine editing
HUR98_RS07680	COG0583	DNA-binding transcription factor activity
HUR98_RS07700	COG2116	formate transmembrane transporter activity
HUR98_RS07705	COG2853	Lipoprotein
HUR98_RS07715	COG3691	Protein conserved in bacteria
HUR98_RS07730	COG2062	phosphohistidine phosphatase, SixA
HUR98_RS07755	COG0730	response to heat
HUR98_RS07760	COG3101	peptidyl-lysine hydroxylation
HUR98_RS07775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUR98_RS07795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUR98_RS07805	COG0586	Pfam SNARE associated Golgi protein
HUR98_RS07815	COG0285	dihydrofolate synthase activity
HUR98_RS07820	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HUR98_RS07825	COG1286	toxin biosynthetic process
HUR98_RS07830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HUR98_RS07835	COG0163	prenyltransferase activity
HUR98_RS07860	COG4160	amino acid transport
HUR98_RS07865	COG4598	ABC transporter
HUR98_RS07880	COG1090	epimerase
HUR98_RS07885	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUR98_RS07890	COG0625	glutathione transferase activity
HUR98_RS07895	COG0625	glutathione transferase activity
HUR98_RS07900	COG0622	Phosphoesterase
HUR98_RS07905	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUR98_RS07910	COG0857	belongs to the CobB CobQ family
HUR98_RS07910	COG0280	phosphate acetyltransferase
HUR98_RS07930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUR98_RS07935	COG0471	metal ion transport
HUR98_RS07935	COG0490	domain, Protein
HUR98_RS07945	COG0436	Aminotransferase
HUR98_RS07950	COG0583	DNA-binding transcription factor activity
HUR98_RS07995	COG0839	Belongs to the complex I subunit 6 family
HUR98_RS08005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUR98_RS08010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUR98_RS08025	COG2153	protein acetylation
HUR98_RS08030	COG1169	isochorismate synthase
HUR98_RS08055	COG0318	PFAM AMP-dependent synthetase and ligase
HUR98_RS08065	COG5464	transposase or invertase
HUR98_RS08080	COG1414	Transcriptional regulator
HUR98_RS08090	COG2271	Major facilitator Superfamily
HUR98_RS08100	COG0247	lactate metabolic process
HUR98_RS08110	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUR98_RS08115	COG2271	Major facilitator Superfamily
HUR98_RS08120	COG0584	glycerophosphoryl diester phosphodiesterase
HUR98_RS08125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUR98_RS08150	COG2205	protein histidine kinase activity
HUR98_RS08150	COG0784	Response regulator, receiver
HUR98_RS08160	COG0642	Histidine kinase
HUR98_RS08160	COG2198	Histidine kinase
HUR98_RS08175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUR98_RS08175	COG2169	Transcriptional regulator
HUR98_RS08180	COG3145	DNA-N1-methyladenine dioxygenase activity
HUR98_RS08185	COG4615	Cyclic peptide transporter
HUR98_RS08190	COG2239	Acts as a magnesium transporter
HUR98_RS08195	COG0659	secondary active sulfate transmembrane transporter activity
HUR98_RS08210	COG0628	permease
HUR98_RS08235	COG1349	DNA-binding transcription factor activity
HUR98_RS08240	COG0494	nUDIX hydrolase
HUR98_RS08260	COG1061	Type III restriction enzyme res subunit
HUR98_RS08265	COG1187	pseudouridine synthase activity
HUR98_RS08270	COG2814	Major facilitator Superfamily
HUR98_RS08280	COG4172	Belongs to the ABC transporter superfamily
HUR98_RS08285	COG4239	(ABC) transporter, permease
HUR98_RS08290	COG4174	ABC transporter (Permease)
HUR98_RS08295	COG4166	transmembrane transport
HUR98_RS08300	COG2200	EAL domain
HUR98_RS08305	COG0791	NLP P60 protein
HUR98_RS08310	COG0671	phosphoesterase, PA-phosphatase related
HUR98_RS08315	COG0523	cobalamin synthesis protein
HUR98_RS08320	COG0246	Mannitol dehydrogenase
HUR98_RS08325	COG1312	Catalyzes the dehydration of D-mannonate
HUR98_RS08350	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS08350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS08355	COG1105	Belongs to the carbohydrate kinase PfkB family
HUR98_RS08360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUR98_RS08360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUR98_RS08360	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HUR98_RS08370	COG2855	membrane
HUR98_RS08375	COG0583	DNA-binding transcription factor activity
HUR98_RS08380	COG0833	amino acid
HUR98_RS08390	COG4771	TonB-dependent receptor
HUR98_RS08405	COG2311	Membrane
HUR98_RS08420	COG1129	ABC transporter
HUR98_RS08430	COG2949	membrane
HUR98_RS08440	COG1346	cytolysis
HUR98_RS08450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUR98_RS08455	COG3659	wide pore channel activity
HUR98_RS08470	COG2723	6-phospho-beta-galactosidase activity
HUR98_RS08475	COG1538	Outer membrane efflux protein
HUR98_RS08480	COG0586	Pfam SNARE associated Golgi protein
HUR98_RS08490	COG1686	Belongs to the peptidase S11 family
HUR98_RS08505	COG0277	FAD linked oxidase domain protein
HUR98_RS08510	COG1472	Belongs to the glycosyl hydrolase 3 family
HUR98_RS08515	COG1732	Glycine betaine
HUR98_RS08520	COG1174	glycine betaine transport
HUR98_RS08525	COG1125	glycine betaine transport
HUR98_RS08530	COG1174	glycine betaine transport
HUR98_RS08540	COG3275	phosphorelay sensor kinase activity
HUR98_RS08550	COG4807	Protein conserved in bacteria
HUR98_RS08570	COG5455	response to cobalt ion
HUR98_RS08575	COG0583	DNA-binding transcription factor activity
HUR98_RS08580	COG2252	PERMEase
HUR98_RS08590	COG0583	DNA-binding transcription factor activity
HUR98_RS08605	COG0351	phosphomethylpyrimidine kinase
HUR98_RS08610	COG1830	Aldolase
HUR98_RS08620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUR98_RS08645	COG1070	Carbohydrate kinase
HUR98_RS08655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUR98_RS08660	COG4948	Mandelate Racemase Muconate Lactonizing
HUR98_RS08665	COG0747	negative chemotaxis
HUR98_RS08670	COG0601	transmembrane transport
HUR98_RS08680	COG0444	Belongs to the ABC transporter superfamily
HUR98_RS08685	COG4608	Belongs to the ABC transporter superfamily
HUR98_RS08700	COG0745	RESPONSE REGULATOR receiver
HUR98_RS08705	COG2205	protein histidine kinase activity
HUR98_RS08730	COG1301	dicarboxylic acid transport
HUR98_RS08750	COG5002	protein histidine kinase activity
HUR98_RS08755	COG0443	Heat shock 70 kDa protein
HUR98_RS08760	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HUR98_RS08775	COG2982	Protein involved in outer membrane biogenesis
HUR98_RS08780	COG1253	flavin adenine dinucleotide binding
HUR98_RS08840	COG1215	transferase activity, transferring glycosyl groups
HUR98_RS08850	COG0438	transferase activity, transferring glycosyl groups
HUR98_RS08885	COG1088	dTDP-glucose 4,6-dehydratase activity
HUR98_RS08910	COG3039	Transposase
HUR98_RS08960	COG0438	transferase activity, transferring glycosyl groups
HUR98_RS08965	COG1215	transferase activity, transferring glycosyl groups
HUR98_RS08985	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUR98_RS09015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUR98_RS09020	COG0583	DNA-binding transcription factor activity
HUR98_RS09030	COG0531	amino acid
HUR98_RS09035	COG0640	Transcriptional regulator
HUR98_RS09040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUR98_RS09050	COG2925	Exonuclease
HUR98_RS09060	COG3344	reverse transcriptase
HUR98_RS09070	COG1289	transmembrane transporter activity
HUR98_RS09090	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUR98_RS09100	COG1942	4-Oxalocrotonate Tautomerase
HUR98_RS09105	COG0583	DNA-binding transcription factor activity
HUR98_RS09110	COG0095	Lipoate-protein ligase
HUR98_RS09115	COG0477	Major facilitator Superfamily
HUR98_RS09125	COG3300	MHYT domain
HUR98_RS09125	COG5001	Diguanylate cyclase
HUR98_RS09135	COG3615	Tellurite resistance protein tehB
HUR98_RS09160	COG3706	GGDEF domain
HUR98_RS09210	COG2003	Belongs to the UPF0758 family
HUR98_RS09255	COG3504	Conjugal transfer protein
HUR98_RS09325	COG4771	TonB-dependent receptor
HUR98_RS09330	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUR98_RS09350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUR98_RS09350	COG2226	methyltransferase
HUR98_RS09350	COG3433	isochorismatase activity
HUR98_RS09365	COG1132	(ABC) transporter
HUR98_RS09370	COG2814	Major facilitator Superfamily
HUR98_RS09375	COG1169	isochorismate synthase
HUR98_RS09380	COG0582	viral genome integration into host DNA
HUR98_RS09390	COG0534	Mate efflux family protein
HUR98_RS09400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUR98_RS09420	COG0604	alcohol dehydrogenase
HUR98_RS09430	COG0025	NhaP-type Na H and K H
HUR98_RS09475	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HUR98_RS09485	COG1418	mRNA catabolic process
HUR98_RS09490	COG0270	DNA (cytosine-5-)-methyltransferase activity
HUR98_RS09495	COG3727	T/G mismatch-specific endonuclease activity
HUR98_RS09500	COG0697	spore germination
HUR98_RS09505	COG2354	Protein conserved in bacteria
HUR98_RS09535	COG0366	Alpha amylase catalytic
HUR98_RS09560	COG2197	response regulator
HUR98_RS09570	COG2197	response regulator
HUR98_RS09605	COG3318	Belongs to the UPF0149 family
HUR98_RS09605	COG3012	SEC-C Motif Domain Protein
HUR98_RS09610	COG0814	amino acid
HUR98_RS09620	COG1528	Iron-storage protein
HUR98_RS09635	COG0477	Major facilitator Superfamily
HUR98_RS09645	COG2211	Major facilitator Superfamily
HUR98_RS09655	COG1528	Iron-storage protein
HUR98_RS09665	COG1879	ABC-type sugar transport system periplasmic component
HUR98_RS09675	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS09700	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HUR98_RS09710	COG3102	Protein conserved in bacteria
HUR98_RS09730	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HUR98_RS09735	COG1801	Protein of unknown function DUF72
HUR98_RS09740	COG1335	isochorismatase
HUR98_RS09750	COG0494	nUDIX hydrolase
HUR98_RS09775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUR98_RS09785	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HUR98_RS09790	COG0739	heme binding
HUR98_RS09795	COG1560	Kdo2-lipid A biosynthetic process
HUR98_RS09805	COG1737	Transcriptional regulator
HUR98_RS09815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HUR98_RS09820	COG0129	dihydroxy-acid dehydratase activity
HUR98_RS09825	COG0800	Aldolase
HUR98_RS09835	COG3141	response to X-ray
HUR98_RS09840	COG2979	Protein of unknown function (DUF533)
HUR98_RS09845	COG1770	oligopeptidase
HUR98_RS09850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUR98_RS09860	COG2372	response to copper ion
HUR98_RS09865	COG1276	copper resistance
HUR98_RS09880	COG2990	Protein conserved in bacteria
HUR98_RS09905	COG3008	intermembrane lipid transfer
HUR98_RS09910	COG2995	paraquat-inducible protein a
HUR98_RS09915	COG1956	GAF domain-containing protein
HUR98_RS09935	COG2814	Major facilitator Superfamily
HUR98_RS09940	COG1414	Transcriptional regulator
HUR98_RS09970	COG0768	penicillin binding
HUR98_RS09975	COG2226	methyltransferase
HUR98_RS09990	COG3716	PTS system mannose fructose sorbose family IID component
HUR98_RS09995	COG3715	PTS system
HUR98_RS10000	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS10000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUR98_RS10005	COG1253	flavin adenine dinucleotide binding
HUR98_RS10010	COG2200	EAL domain
HUR98_RS10015	COG1760	l-serine dehydratase
HUR98_RS10035	COG0251	oxidation-reduction process
HUR98_RS10040	COG1199	ATP-dependent helicase activity
HUR98_RS10050	COG3065	identical protein binding
HUR98_RS10060	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HUR98_RS10070	COG2894	cell division
HUR98_RS10085	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUR98_RS10115	COG2719	SpoVR family
HUR98_RS10140	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUR98_RS10150	COG4774	siderophore transport
HUR98_RS10165	COG2308	Evidence 4 Homologs of previously reported genes of
HUR98_RS10205	COG0583	DNA-binding transcription factor activity
HUR98_RS10210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUR98_RS10225	COG1882	Formate acetyltransferase
HUR98_RS10260	COG0583	DNA-binding transcription factor activity
HUR98_RS10290	COG0583	DNA-binding transcription factor activity
HUR98_RS10305	COG3122	Protein conserved in bacteria
HUR98_RS10325	COG2885	chlorophyll binding
HUR98_RS10335	COG3501	Rhs element vgr protein
HUR98_RS10460	COG0012	GTP binding
HUR98_RS10480	COG0659	secondary active sulfate transmembrane transporter activity
HUR98_RS10510	COG2890	protein-(glutamine-N5) methyltransferase activity
HUR98_RS10530	COG0387	Pfam Sodium calcium exchanger
HUR98_RS10535	COG4572	Cation transport regulator
HUR98_RS10540	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HUR98_RS10550	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HUR98_RS10555	COG3707	response regulator
HUR98_RS10560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUR98_RS10570	COG1116	anion transmembrane transporter activity
HUR98_RS10575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUR98_RS10575	COG2146	nitrite reductase [NAD(P)H] activity
HUR98_RS10580	COG0243	molybdopterin cofactor binding
HUR98_RS10585	COG4932	domain protein
HUR98_RS10590	COG2197	response regulator
HUR98_RS10595	COG3850	Histidine kinase
HUR98_RS10600	COG2223	nitrite transmembrane transporter activity
HUR98_RS10610	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HUR98_RS10615	COG1140	nitrate reductase beta subunit
HUR98_RS10620	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HUR98_RS10625	COG2181	nitrate reductase activity
HUR98_RS10635	COG1522	sequence-specific DNA binding
HUR98_RS10670	COG0788	formyltetrahydrofolate deformylase activity
HUR98_RS10680	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUR98_RS10685	COG0745	RESPONSE REGULATOR receiver
HUR98_RS10690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUR98_RS10695	COG2916	Histone family protein nucleoid-structuring protein H-NS
HUR98_RS10705	COG1435	thymidine kinase activity
HUR98_RS10710	COG1454	alcohol dehydrogenase
HUR98_RS10710	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS10720	COG2095	MarC family integral membrane protein
HUR98_RS10725	COG4166	transmembrane transport
HUR98_RS10730	COG0601	transmembrane transport
HUR98_RS10735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUR98_RS10740	COG0444	Belongs to the ABC transporter superfamily
HUR98_RS10750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUR98_RS10770	COG2353	YceI-like domain
HUR98_RS10780	COG2350	Protein conserved in bacteria
HUR98_RS10790	COG3001	Fructosamine kinase
HUR98_RS10800	COG1105	Belongs to the carbohydrate kinase PfkB family
HUR98_RS10805	COG3137	Salt-induced outer membrane protein
HUR98_RS10845	COG0072	phenylalanine-tRNA ligase activity
HUR98_RS10845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUR98_RS10865	COG0583	DNA-binding transcription factor activity
HUR98_RS10885	COG0386	Belongs to the glutathione peroxidase family
HUR98_RS10895	COG0791	NLP P60 protein
HUR98_RS10905	COG4256	Hemin uptake protein
HUR98_RS10910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUR98_RS10925	COG0574	Belongs to the PEP-utilizing enzyme family
HUR98_RS10925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUR98_RS10935	COG0628	permease
HUR98_RS10940	COG0277	FAD linked oxidase domain protein
HUR98_RS10940	COG0247	lactate metabolic process
HUR98_RS10945	COG2050	protein possibly involved in aromatic compounds catabolism
HUR98_RS10950	COG2261	transglycosylase associated protein
HUR98_RS10975	COG1120	ATPase activity
HUR98_RS10980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUR98_RS10990	COG0583	DNA-binding transcription factor activity
HUR98_RS11015	COG1304	FMN binding
HUR98_RS11020	COG1309	transcriptional regulator
HUR98_RS11040	COG0316	Belongs to the HesB IscA family
HUR98_RS11045	COG0719	Fe-S assembly protein
HUR98_RS11050	COG0396	ATPase activity
HUR98_RS11055	COG0719	Fe-S assembly protein
HUR98_RS11070	COG1376	ErfK ybiS ycfS ynhG family protein
HUR98_RS11100	COG1309	transcriptional regulator
HUR98_RS11110	COG2271	Major facilitator Superfamily
HUR98_RS11115	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUR98_RS11140	COG1414	Transcriptional regulator
HUR98_RS11175	COG2814	Major facilitator Superfamily
HUR98_RS11195	COG0583	DNA-binding transcription factor activity
HUR98_RS11200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUR98_RS11220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUR98_RS11225	COG1116	anion transmembrane transporter activity
HUR98_RS11230	COG4774	siderophore transport
HUR98_RS11235	COG1120	ATPase activity
HUR98_RS11240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUR98_RS11245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUR98_RS11265	COG0765	amino acid transport
HUR98_RS11270	COG1126	abc transporter atp-binding protein
HUR98_RS11310	COG3383	formate dehydrogenase (NAD+) activity
HUR98_RS11315	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HUR98_RS11325	COG1175	transmembrane transport
HUR98_RS11355	COG4133	protoheme IX ABC transporter activity
HUR98_RS11360	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUR98_RS11365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUR98_RS11380	COG1138	Cytochrome C-type biogenesis protein
HUR98_RS11385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUR98_RS11390	COG3088	subunit of a heme lyase
HUR98_RS11390	COG4235	cytochrome complex assembly
HUR98_RS11410	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HUR98_RS11445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUR98_RS11480	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS11485	COG2610	gluconate transmembrane transporter activity
HUR98_RS11490	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUR98_RS11500	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUR98_RS11510	COG0583	DNA-binding transcription factor activity
HUR98_RS11535	COG0277	FAD linked oxidase domain protein
HUR98_RS11540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUR98_RS11565	COG0402	S-adenosylhomocysteine deaminase activity
HUR98_RS11610	COG3321	synthase
HUR98_RS11610	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS11610	COG0604	alcohol dehydrogenase
HUR98_RS11640	COG4608	Belongs to the ABC transporter superfamily
HUR98_RS11645	COG0444	Belongs to the ABC transporter superfamily
HUR98_RS11670	COG0346	lactoylglutathione lyase activity
HUR98_RS11675	COG1349	DNA-binding transcription factor activity
HUR98_RS11710	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HUR98_RS11760	COG0307	riboflavin synthase, alpha
HUR98_RS11765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUR98_RS11770	COG2814	Major facilitator Superfamily
HUR98_RS11775	COG0583	DNA-binding transcription factor activity
HUR98_RS11790	COG2814	Major facilitator Superfamily
HUR98_RS11805	COG0791	NLP P60 protein
HUR98_RS11810	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HUR98_RS11820	COG0346	lactoylglutathione lyase activity
HUR98_RS11825	COG1902	pentaerythritol trinitrate reductase activity
HUR98_RS11830	COG1309	transcriptional regulator
HUR98_RS11835	COG3313	Fe-S protein
HUR98_RS11840	COG4989	oxidoreductase activity
HUR98_RS11845	COG2032	superoxide dismutase activity
HUR98_RS11850	COG1289	transmembrane transporter activity
HUR98_RS11855	COG1566	PFAM secretion protein HlyD family protein
HUR98_RS11870	COG3706	GGDEF domain
HUR98_RS11885	COG3895	Periplasmic Protein
HUR98_RS11900	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HUR98_RS11905	COG0625	glutathione transferase activity
HUR98_RS11915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUR98_RS11925	COG4659	FMN binding
HUR98_RS11960	COG2723	6-phospho-beta-galactosidase activity
HUR98_RS11970	COG0673	inositol 2-dehydrogenase activity
HUR98_RS11980	COG2814	Major facilitator Superfamily
HUR98_RS12000	COG3038	cytochrome b561
HUR98_RS12020	COG0583	DNA-binding transcription factor activity
HUR98_RS12025	COG3485	protocatechuate 3,4-dioxygenase
HUR98_RS12030	COG3485	protocatechuate 3,4-dioxygenase
HUR98_RS12035	COG5383	Protein conserved in bacteria
HUR98_RS12040	COG2272	Belongs to the type-B carboxylesterase lipase family
HUR98_RS12055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUR98_RS12060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUR98_RS12065	COG1275	C4-dicarboxylate transporter malic acid transport protein
HUR98_RS12070	COG0500	methyltransferase
HUR98_RS12085	COG2207	Transcriptional regulator
HUR98_RS12085	COG3708	Transcriptional regulator
HUR98_RS12090	COG3135	benzoate transporter
HUR98_RS12095	COG1396	sequence-specific DNA binding
HUR98_RS12105	COG0826	peptidase U32
HUR98_RS12125	COG1294	oxidase, subunit
HUR98_RS12130	COG1271	oxidase subunit
HUR98_RS12135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUR98_RS12140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUR98_RS12145	COG3842	ATPase activity
HUR98_RS12150	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUR98_RS12155	COG1177	transmembrane transport
HUR98_RS12160	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS12195	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS12200	COG0747	negative chemotaxis
HUR98_RS12210	COG3238	Protein conserved in bacteria
HUR98_RS12215	COG1247	-acetyltransferase
HUR98_RS12225	COG2130	NADP-dependent
HUR98_RS12240	COG3691	Protein conserved in bacteria
HUR98_RS12245	COG1228	amidohydrolase
HUR98_RS12250	COG4772	TonB-dependent receptor
HUR98_RS12275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUR98_RS12280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUR98_RS12285	COG1473	amidohydrolase
HUR98_RS12290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUR98_RS12305	COG0765	amino acid transport
HUR98_RS12310	COG1126	abc transporter atp-binding protein
HUR98_RS12320	COG0625	glutathione transferase activity
HUR98_RS12355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUR98_RS12360	COG3842	ATPase activity
HUR98_RS12365	COG1840	ABC-type Fe3 transport system, periplasmic component
HUR98_RS12370	COG1178	ABC-type Fe3 transport system permease component
HUR98_RS12375	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HUR98_RS12380	COG2181	nitrate reductase activity
HUR98_RS12385	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HUR98_RS12390	COG1140	nitrate reductase beta subunit
HUR98_RS12395	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HUR98_RS12415	COG1414	Transcriptional regulator
HUR98_RS12420	COG4948	Mandelate Racemase Muconate Lactonizing
HUR98_RS12425	COG4829	muconolactone delta-isomerase
HUR98_RS12430	COG3485	protocatechuate 3,4-dioxygenase
HUR98_RS12440	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HUR98_RS12465	COG0437	4 iron, 4 sulfur cluster binding
HUR98_RS12470	COG2864	formate dehydrogenase
HUR98_RS12485	COG2326	polyphosphate kinase activity
HUR98_RS12495	COG2814	Major facilitator Superfamily
HUR98_RS12505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUR98_RS12525	COG0747	negative chemotaxis
HUR98_RS12530	COG1064	alcohol dehydrogenase
HUR98_RS12545	COG0488	(ABC) transporter
HUR98_RS12590	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS12595	COG3729	General stress protein
HUR98_RS12605	COG3685	Protein conserved in bacteria
HUR98_RS12615	COG0366	Alpha amylase catalytic
HUR98_RS12625	COG2323	membrane
HUR98_RS12635	COG3111	PFAM Bacterial OB fold (BOF) protein
HUR98_RS12645	COG1764	response to oxidative stress
HUR98_RS12670	COG3781	membrane
HUR98_RS12675	COG0243	molybdopterin cofactor binding
HUR98_RS12680	COG0583	DNA-binding transcription factor activity
HUR98_RS12685	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS12710	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS12715	COG1447	Phosphotransferase system cellobiose-specific component IIA
HUR98_RS12720	COG2814	Major facilitator Superfamily
HUR98_RS12725	COG1285	pathogenesis
HUR98_RS12730	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HUR98_RS12740	COG0583	DNA-binding transcription factor activity
HUR98_RS12760	COG0519	Catalyzes the synthesis of GMP from XMP
HUR98_RS12760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUR98_RS12800	COG0596	Alpha beta hydrolase
HUR98_RS12805	COG0745	RESPONSE REGULATOR receiver
HUR98_RS12810	COG2205	protein histidine kinase activity
HUR98_RS12825	COG0076	glutamate decarboxylase activity
HUR98_RS12830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUR98_RS12835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUR98_RS12840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUR98_RS12845	COG1116	anion transmembrane transporter activity
HUR98_RS12850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HUR98_RS12865	COG0673	inositol 2-dehydrogenase activity
HUR98_RS12875	COG1609	Transcriptional regulator
HUR98_RS12880	COG3706	GGDEF domain
HUR98_RS12885	COG0402	S-adenosylhomocysteine deaminase activity
HUR98_RS12890	COG1953	Uracil, thiamine, allantoin
HUR98_RS12930	COG0406	alpha-ribazole phosphatase activity
HUR98_RS12935	COG1335	isochorismatase
HUR98_RS12965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUR98_RS13045	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HUR98_RS13055	COG2070	2-Nitropropane dioxygenase
HUR98_RS13060	COG0583	DNA-binding transcription factor activity
HUR98_RS13070	COG1902	pentaerythritol trinitrate reductase activity
HUR98_RS13075	COG4529	Protein conserved in bacteria
HUR98_RS13080	COG0477	Major facilitator Superfamily
HUR98_RS13110	COG2223	nitrite transmembrane transporter activity
HUR98_RS13120	COG1609	Transcriptional regulator
HUR98_RS13125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS13135	COG3037	sugar-specific permease SgaT UlaA
HUR98_RS13140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUR98_RS13150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUR98_RS13155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUR98_RS13155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUR98_RS13155	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HUR98_RS13170	COG0583	DNA-binding transcription factor activity
HUR98_RS13175	COG0583	DNA-binding transcription factor activity
HUR98_RS13180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUR98_RS13190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUR98_RS13205	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS13215	COG1609	Transcriptional regulator
HUR98_RS13245	COG1652	LysM domain
HUR98_RS13260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUR98_RS13260	COG0426	domain, Protein
HUR98_RS13285	COG0456	acetyltransferase
HUR98_RS13285	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HUR98_RS13295	COG0667	Aldo Keto reductase
HUR98_RS13300	COG0667	Aldo Keto reductase
HUR98_RS13310	COG0667	Aldo Keto reductase
HUR98_RS13330	COG4977	sequence-specific DNA binding
HUR98_RS13350	COG4977	sequence-specific DNA binding
HUR98_RS13355	COG1349	DNA-binding transcription factor activity
HUR98_RS13370	COG1349	DNA-binding transcription factor activity
HUR98_RS13375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUR98_RS13380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUR98_RS13385	COG0738	Major facilitator superfamily
HUR98_RS13430	COG1929	Belongs to the glycerate kinase type-1 family
HUR98_RS13435	COG3835	regulator
HUR98_RS13455	COG2186	Transcriptional regulator
HUR98_RS13460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUR98_RS13460	COG1263	PTS System
HUR98_RS13470	COG2814	Major facilitator Superfamily
HUR98_RS13475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS13475	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS13490	COG2819	hydrolase of the alpha beta superfamily
HUR98_RS13495	COG5001	Diguanylate cyclase
HUR98_RS13495	COG3300	MHYT domain
HUR98_RS13530	COG3188	usher protein
HUR98_RS13545	COG3550	peptidyl-serine autophosphorylation
HUR98_RS13550	COG1396	sequence-specific DNA binding
HUR98_RS13555	COG2351	hydroxyisourate hydrolase activity
HUR98_RS13560	COG3195	allantoin biosynthetic process
HUR98_RS13560	COG3648	Uricase
HUR98_RS13565	COG2233	PERMEase
HUR98_RS13595	COG2207	Transcriptional regulator
HUR98_RS13610	COG4628	conserved protein (DUF2132)
HUR98_RS13630	COG2011	ABC-type metal ion transport system permease component
HUR98_RS13635	COG2070	2-Nitropropane dioxygenase
HUR98_RS13645	COG0477	Major facilitator Superfamily
HUR98_RS13715	COG2199	diguanylate cyclase activity
HUR98_RS13730	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS13735	COG0583	DNA-binding transcription factor activity
HUR98_RS13745	COG0039	L-malate dehydrogenase activity
HUR98_RS13750	COG1349	DNA-binding transcription factor activity
HUR98_RS13755	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HUR98_RS13760	COG3395	kinase activity
HUR98_RS13770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUR98_RS13785	COG2731	YhcH YjgK YiaL family protein
HUR98_RS13790	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS13820	COG4977	sequence-specific DNA binding
HUR98_RS13830	COG0697	spore germination
HUR98_RS13835	COG2814	Major facilitator Superfamily
HUR98_RS13845	COG0410	ABC transporter
HUR98_RS13850	COG1129	ABC transporter
HUR98_RS13865	COG0683	leucine binding
HUR98_RS13870	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUR98_RS13905	COG2223	nitrite transmembrane transporter activity
HUR98_RS13910	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUR98_RS13925	COG1349	DNA-binding transcription factor activity
HUR98_RS13930	COG2084	Dehydrogenase
HUR98_RS13935	COG3395	kinase activity
HUR98_RS13940	COG0235	Class ii aldolase
HUR98_RS13945	COG3622	Belongs to the hyi family
HUR98_RS13950	COG2610	gluconate transmembrane transporter activity
HUR98_RS13955	COG3708	Transcriptional regulator
HUR98_RS13955	COG2207	Transcriptional regulator
HUR98_RS13970	COG2200	EAL domain
HUR98_RS13975	COG1546	Belongs to the CinA family
HUR98_RS13980	COG0071	Belongs to the small heat shock protein (HSP20) family
HUR98_RS13995	COG2197	response regulator
HUR98_RS14010	COG2135	peptidase activity
HUR98_RS14015	COG2207	Transcriptional regulator
HUR98_RS14030	COG4221	oxidoreductase activity
HUR98_RS14035	COG1802	Transcriptional regulator
HUR98_RS14040	COG0589	response to stress
HUR98_RS14045	COG0246	Mannitol dehydrogenase
HUR98_RS14050	COG2271	Major facilitator Superfamily
HUR98_RS14065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUR98_RS14080	COG0243	molybdopterin cofactor binding
HUR98_RS14085	COG0437	4 iron, 4 sulfur cluster binding
HUR98_RS14090	COG3302	dmso reductase anchor subunit
HUR98_RS14105	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUR98_RS14110	COG1940	carbohydrate kinase activity
HUR98_RS14115	COG0583	DNA-binding transcription factor activity
HUR98_RS14120	COG2814	Major facilitator Superfamily
HUR98_RS14125	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HUR98_RS14135	COG3591	Belongs to the peptidase S1B family
HUR98_RS14155	COG0628	permease
HUR98_RS14185	COG0679	Auxin Efflux Carrier
HUR98_RS14195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUR98_RS14220	COG3290	protein histidine kinase activity
HUR98_RS14225	COG4565	transcriptional regulatory protein
HUR98_RS14245	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUR98_RS14245	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUR98_RS14255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUR98_RS14260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUR98_RS14270	COG0183	Belongs to the thiolase family
HUR98_RS14275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUR98_RS14285	COG1414	Transcriptional regulator
HUR98_RS14290	COG2840	Smr protein MutS2
HUR98_RS14295	COG0583	DNA-binding transcription factor activity
HUR98_RS14305	COG1473	amidohydrolase
HUR98_RS14310	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HUR98_RS14325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUR98_RS14340	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HUR98_RS14345	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUR98_RS14360	COG0531	amino acid
HUR98_RS14370	COG3136	membrane protein required for alginate biosynthesis
HUR98_RS14375	COG0745	RESPONSE REGULATOR receiver
HUR98_RS14385	COG2205	protein histidine kinase activity
HUR98_RS14395	COG0114	fumarate hydratase activity
HUR98_RS14400	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUR98_RS14400	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUR98_RS14405	COG1482	cell wall glycoprotein biosynthetic process
HUR98_RS14410	COG5339	Protein conserved in bacteria
HUR98_RS14415	COG1609	Transcriptional regulator
HUR98_RS14420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUR98_RS14420	COG1263	PTS System
HUR98_RS14425	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HUR98_RS14450	COG2391	methyltransferase activity
HUR98_RS14455	COG0425	Belongs to the sulfur carrier protein TusA family
HUR98_RS14460	COG5562	phage envelope protein
HUR98_RS14465	COG0401	homolog of Blt101
HUR98_RS14470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUR98_RS14475	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS14485	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HUR98_RS14490	COG0477	Major facilitator Superfamily
HUR98_RS14495	COG1113	amino acid transport
HUR98_RS14500	COG2988	succinylglutamate desuccinylase activity
HUR98_RS14505	COG3724	N-succinylarginine dihydrolase activity
HUR98_RS14510	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS14515	COG3138	arginine N-succinyltransferase
HUR98_RS14520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUR98_RS14530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUR98_RS14535	COG0667	Aldo Keto reductase
HUR98_RS14540	COG0583	DNA-binding transcription factor activity
HUR98_RS14565	COG4122	O-methyltransferase activity
HUR98_RS14570	COG1643	Atp-dependent helicase
HUR98_RS14585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUR98_RS14590	COG3327	negative regulation of DNA-templated transcription, initiation
HUR98_RS14595	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HUR98_RS14600	COG0183	Belongs to the thiolase family
HUR98_RS14605	COG2050	protein possibly involved in aromatic compounds catabolism
HUR98_RS14610	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUR98_RS14615	COG1024	Enoyl-CoA hydratase
HUR98_RS14620	COG1024	Enoyl-CoA hydratase
HUR98_RS14625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUR98_RS14630	COG2151	metal-sulfur cluster biosynthetic enzyme
HUR98_RS14635	COG3396	Phenylacetate-CoA oxygenase
HUR98_RS14640	COG3460	Phenylacetate-CoA oxygenase
HUR98_RS14645	COG3396	Phenylacetate-CoA oxygenase
HUR98_RS14650	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS14650	COG2030	dehydratase
HUR98_RS14670	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS14675	COG2207	Transcriptional regulator
HUR98_RS14680	COG3784	Protein of unknown function (DUF1318)
HUR98_RS14690	COG2911	Protein conserved in bacteria
HUR98_RS14695	COG0586	Pfam SNARE associated Golgi protein
HUR98_RS14700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUR98_RS14705	COG3187	Heat shock protein
HUR98_RS14710	COG3042	response to heat
HUR98_RS14715	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUR98_RS14715	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUR98_RS14715	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUR98_RS14715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUR98_RS14720	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HUR98_RS14730	COG0589	response to stress
HUR98_RS14740	COG0513	Belongs to the DEAD box helicase family
HUR98_RS14750	COG1349	DNA-binding transcription factor activity
HUR98_RS14755	COG0673	inositol 2-dehydrogenase activity
HUR98_RS14770	COG1113	amino acid transport
HUR98_RS14775	COG1522	sequence-specific DNA binding
HUR98_RS14785	COG1448	Aminotransferase
HUR98_RS14790	COG2011	ABC-type metal ion transport system permease component
HUR98_RS14805	COG0436	Aminotransferase
HUR98_RS14810	COG0604	alcohol dehydrogenase
HUR98_RS14840	COG0583	DNA-binding transcription factor activity
HUR98_RS14860	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS14865	COG1309	transcriptional regulator
HUR98_RS14870	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS14965	COG2885	chlorophyll binding
HUR98_RS15080	COG0739	heme binding
HUR98_RS15080	COG0741	lytic transglycosylase activity
HUR98_RS15080	COG1196	nuclear chromosome segregation
HUR98_RS15150	COG3567	Phage-associated protein, HI1409 family
HUR98_RS15155	COG1783	phage Terminase large subunit
HUR98_RS15175	COG3772	lysozyme
HUR98_RS15185	COG0484	heat shock protein binding
HUR98_RS15290	COG0582	viral genome integration into host DNA
HUR98_RS15295	COG0693	protein deglycase activity
HUR98_RS15300	COG1078	dGTPase activity
HUR98_RS15305	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS15310	COG0583	DNA-binding transcription factor activity
HUR98_RS15330	COG0656	L-ascorbic acid biosynthetic process
HUR98_RS15360	COG4166	transmembrane transport
HUR98_RS15370	COG2866	Carboxypeptidase
HUR98_RS15375	COG4948	Mandelate Racemase Muconate Lactonizing
HUR98_RS15380	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HUR98_RS15385	COG3180	Ammonia monooxygenase
HUR98_RS15395	COG1486	melibiose metabolic process
HUR98_RS15400	COG0583	DNA-binding transcription factor activity
HUR98_RS15410	COG3106	COG3106 Predicted ATPase
HUR98_RS15420	COG1983	PspC domain protein
HUR98_RS15430	COG1842	Phage shock protein A
HUR98_RS15435	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HUR98_RS15445	COG1473	amidohydrolase
HUR98_RS15460	COG0702	epimerase
HUR98_RS15475	COG2135	peptidase activity
HUR98_RS15485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUR98_RS15490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUR98_RS15495	COG3344	reverse transcriptase
HUR98_RS15550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUR98_RS15665	COG4171	peptide transport system, permease
HUR98_RS15680	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HUR98_RS15690	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUR98_RS15695	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUR98_RS15695	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUR98_RS15710	COG1349	DNA-binding transcription factor activity
HUR98_RS15720	COG0023	Translation Initiation Factor
HUR98_RS15730	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HUR98_RS15735	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HUR98_RS15740	COG0671	phosphoesterase, PA-phosphatase related
HUR98_RS15750	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUR98_RS15775	COG0616	signal peptide processing
HUR98_RS15785	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS15790	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HUR98_RS15800	COG0583	DNA-binding transcription factor activity
HUR98_RS15810	COG0009	L-threonylcarbamoyladenylate synthase
HUR98_RS15820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUR98_RS15825	COG0512	Glutamine amidotransferase of anthranilate synthase
HUR98_RS15825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUR98_RS15830	COG0134	indole-3-glycerol-phosphate synthase activity
HUR98_RS15830	COG0135	phosphoribosylanthranilate isomerase activity
HUR98_RS15885	COG4774	siderophore transport
HUR98_RS15895	COG3047	cAMP biosynthetic process
HUR98_RS15900	COG0727	PFAM Uncharacterised protein family (UPF0153)
HUR98_RS15930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUR98_RS15935	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS15940	COG1988	membrane-bound metal-dependent
HUR98_RS15955	COG0753	catalase activity
HUR98_RS15965	COG1486	melibiose metabolic process
HUR98_RS15970	COG2169	Transcriptional regulator
HUR98_RS15970	COG1917	Cupin 2, conserved barrel domain protein
HUR98_RS15975	COG1447	Phosphotransferase system cellobiose-specific component IIA
HUR98_RS15980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS15990	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS15995	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUR98_RS16005	COG0322	excinuclease ABC activity
HUR98_RS16010	COG3678	ATP-independent chaperone mediated protein folding
HUR98_RS16020	COG3724	N-succinylarginine dihydrolase activity
HUR98_RS16030	COG3138	arginine N-succinyltransferase
HUR98_RS16040	COG0708	Exodeoxyribonuclease III
HUR98_RS16045	COG0398	Pfam SNARE associated Golgi protein
HUR98_RS16050	COG0398	Pfam SNARE associated Golgi protein
HUR98_RS16055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUR98_RS16060	COG4134	Bacterial extracellular solute-binding protein
HUR98_RS16065	COG4135	transport system, permease component
HUR98_RS16070	COG4136	ATPase activity
HUR98_RS16075	COG2897	thiosulfate sulfurtransferase activity
HUR98_RS16080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUR98_RS16085	COG0494	nUDIX hydrolase
HUR98_RS16090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUR98_RS16095	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS16095	COG3321	synthase
HUR98_RS16095	COG0604	alcohol dehydrogenase
HUR98_RS16100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUR98_RS16105	COG0709	Synthesizes selenophosphate from selenide and ATP
HUR98_RS16120	COG0778	Nitroreductase
HUR98_RS16125	COG0616	signal peptide processing
HUR98_RS16130	COG0252	asparaginase activity
HUR98_RS16135	COG1335	isochorismatase
HUR98_RS16140	COG2814	Major facilitator Superfamily
HUR98_RS16145	COG1349	DNA-binding transcription factor activity
HUR98_RS16150	COG0667	Aldo Keto reductase
HUR98_RS16155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUR98_RS16160	COG0191	fructose-bisphosphate aldolase activity
HUR98_RS16165	COG1063	alcohol dehydrogenase
HUR98_RS16175	COG1063	alcohol dehydrogenase
HUR98_RS16190	COG3139	Protein of unknown function (DUF1315)
HUR98_RS16215	COG3713	MltA-interacting MipA family protein
HUR98_RS16220	COG2766	serine protein kinase
HUR98_RS16235	COG0386	Belongs to the glutathione peroxidase family
HUR98_RS16260	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS16265	COG0583	DNA-binding transcription factor activity
HUR98_RS16270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUR98_RS16275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUR98_RS16280	COG3344	reverse transcriptase
HUR98_RS16290	COG0859	PFAM glycosyl transferase family 9
HUR98_RS16295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUR98_RS16305	COG2207	Transcriptional regulator
HUR98_RS16310	COG2807	transmembrane transport
HUR98_RS16315	COG0504	CTP synthase activity
HUR98_RS16320	COG1683	Conserved Protein
HUR98_RS16325	COG3189	MarR family transcriptional regulator
HUR98_RS16330	COG3042	response to heat
HUR98_RS16335	COG2199	diguanylate cyclase activity
HUR98_RS16335	COG2203	Gaf domain
HUR98_RS16355	COG3182	Iron-regulated membrane protein
HUR98_RS16365	COG1560	Kdo2-lipid A biosynthetic process
HUR98_RS16375	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HUR98_RS16380	COG3706	GGDEF domain
HUR98_RS16385	COG0583	DNA-binding transcription factor activity
HUR98_RS16390	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HUR98_RS16420	COG1294	oxidase, subunit
HUR98_RS16425	COG1271	oxidase subunit
HUR98_RS16430	COG3546	catalase activity
HUR98_RS16435	COG3685	Protein conserved in bacteria
HUR98_RS16440	COG3685	Protein conserved in bacteria
HUR98_RS16445	COG3729	General stress protein
HUR98_RS16450	COG1063	alcohol dehydrogenase
HUR98_RS16455	COG3813	Protein conserved in bacteria
HUR98_RS16475	COG0640	Transcriptional regulator
HUR98_RS16480	COG0538	isocitrate dehydrogenase activity
HUR98_RS16565	COG0616	signal peptide processing
HUR98_RS16580	COG4626	Terminase
HUR98_RS16580	COG1802	Transcriptional regulator
HUR98_RS16625	COG3772	lysozyme
HUR98_RS16650	COG1403	HNH endonuclease
HUR98_RS16670	COG3344	reverse transcriptase
HUR98_RS16720	COG1196	nuclear chromosome segregation
HUR98_RS16760	COG0740	serine-type endopeptidase activity
HUR98_RS16835	COG1403	HNH endonuclease
HUR98_RS16840	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HUR98_RS16870	COG1396	sequence-specific DNA binding
HUR98_RS16925	COG0582	viral genome integration into host DNA
HUR98_RS16930	COG0538	isocitrate dehydrogenase activity
HUR98_RS16935	COG1187	pseudouridine synthase activity
HUR98_RS16955	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUR98_RS16975	COG2205	protein histidine kinase activity
HUR98_RS16980	COG2850	peptidyl-arginine hydroxylation
HUR98_RS17000	COG1177	transmembrane transport
HUR98_RS17015	COG0318	PFAM AMP-dependent synthetase and ligase
HUR98_RS17025	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUR98_RS17035	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUR98_RS17045	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUR98_RS17055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HUR98_RS17060	COG1388	LysM domain
HUR98_RS17060	COG1376	ErfK ybiS ycfS ynhG family protein
HUR98_RS17075	COG1309	transcriptional regulator
HUR98_RS17090	COG3134	Outer membrane lipoprotein
HUR98_RS17095	COG1252	NADH dehydrogenase
HUR98_RS17120	COG5633	Lipoprotein
HUR98_RS17125	COG0537	adenosine 5'-monophosphoramidase activity
HUR98_RS17135	COG0084	hydrolase, TatD family'
HUR98_RS17140	COG0470	DNA polymerase III
HUR98_RS17150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUR98_RS17155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUR98_RS17160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUR98_RS17175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUR98_RS17195	COG1399	metal-binding, possibly nucleic acid-binding protein
HUR98_RS17215	COG1530	ribonuclease E activity
HUR98_RS17220	COG0583	DNA-binding transcription factor activity
HUR98_RS17225	COG2814	Major facilitator Superfamily
HUR98_RS17245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUR98_RS17290	COG1560	Kdo2-lipid A biosynthetic process
HUR98_RS17305	COG5645	(Lipo)protein
HUR98_RS17340	COG3381	protein complex oligomerization
HUR98_RS17365	COG0583	DNA-binding transcription factor activity
HUR98_RS17375	COG1335	isochorismatase
HUR98_RS17385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUR98_RS17390	COG1702	phosphate starvation-inducible protein PhoH
HUR98_RS17410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUR98_RS17420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUR98_RS17435	COG1309	transcriptional regulator
HUR98_RS17470	COG2233	PERMEase
HUR98_RS17480	COG3729	General stress protein
HUR98_RS17510	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS17525	COG0531	amino acid
HUR98_RS17530	COG0174	glutamine synthetase
HUR98_RS17535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUR98_RS17540	COG1917	Cupin 2, conserved barrel domain protein
HUR98_RS17540	COG1396	sequence-specific DNA binding
HUR98_RS17545	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS17550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUR98_RS17555	COG0583	DNA-binding transcription factor activity
HUR98_RS17560	COG0473	3-isopropylmalate dehydrogenase activity
HUR98_RS17565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUR98_RS17570	COG4638	Rieske (2fe-2S)
HUR98_RS17575	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS17580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUR98_RS17605	COG0670	Belongs to the BI1 family
HUR98_RS17620	COG2207	Transcriptional regulator
HUR98_RS17625	COG1881	PFAM PEBP family protein
HUR98_RS17640	COG1832	CoA-binding protein
HUR98_RS17650	COG0210	DNA helicase
HUR98_RS17655	COG3304	Inner membrane component domain
HUR98_RS17660	COG1289	transmembrane transporter activity
HUR98_RS17665	COG3070	regulator of competence-specific genes
HUR98_RS17685	COG1067	ATP-dependent peptidase activity
HUR98_RS17695	COG3130	regulation of translation
HUR98_RS17700	COG3009	Protein conserved in bacteria
HUR98_RS17705	COG3008	intermembrane lipid transfer
HUR98_RS17705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUR98_RS17710	COG2995	paraquat-inducible protein a
HUR98_RS17715	COG0488	(ABC) transporter
HUR98_RS17725	COG3217	Mosc domain protein beta barrel domain protein
HUR98_RS17725	COG0633	Ferredoxin
HUR98_RS17740	COG0431	NADPH-dependent FMN reductase
HUR98_RS17745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUR98_RS17750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUR98_RS17755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUR98_RS17765	COG0308	aminopeptidase N
HUR98_RS17775	COG1473	amidohydrolase
HUR98_RS17785	COG0814	amino acid
HUR98_RS17810	COG1448	Aminotransferase
HUR98_RS17815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUR98_RS17820	COG3108	Peptidase M15
HUR98_RS17825	COG2989	Protein conserved in bacteria
HUR98_RS17835	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HUR98_RS17845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUR98_RS17850	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HUR98_RS17855	COG3173	Aminoglycoside phosphotransferase
HUR98_RS17870	COG3214	Protein conserved in bacteria
HUR98_RS17885	COG2333	competence protein COMEC
HUR98_RS17885	COG0658	competence protein
HUR98_RS17895	COG0539	negative regulation of cytoplasmic translation
HUR98_RS17915	COG2323	membrane
HUR98_RS17920	COG1944	ATP diphosphatase activity
HUR98_RS17925	COG2116	formate transmembrane transporter activity
HUR98_RS17930	COG1882	Formate acetyltransferase
HUR98_RS17935	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUR98_RS17940	COG0477	Major facilitator Superfamily
HUR98_RS17945	COG3302	dmso reductase anchor subunit
HUR98_RS17950	COG0437	4 iron, 4 sulfur cluster binding
HUR98_RS17955	COG0243	molybdopterin cofactor binding
HUR98_RS17965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HUR98_RS17975	COG1178	ABC-type Fe3 transport system permease component
HUR98_RS17975	COG1674	ftsk spoiiie
HUR98_RS17985	COG0492	ferredoxin-NADP+ reductase activity
HUR98_RS17990	COG4988	ABC transporter
HUR98_RS17995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HUR98_RS18010	COG0542	response to heat
HUR98_RS18020	COG1278	Cold shock
HUR98_RS18030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUR98_RS18035	COG3593	DNA synthesis involved in DNA repair
HUR98_RS18045	COG2431	L-lysine efflux transmembrane transporter activity
HUR98_RS18055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUR98_RS18065	COG0028	Belongs to the TPP enzyme family
HUR98_RS18070	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HUR98_RS18075	COG0702	epimerase
HUR98_RS18080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUR98_RS18085	COG3023	N-Acetylmuramoyl-L-alanine amidase
HUR98_RS18090	COG4251	negative regulation of phosphorylation
HUR98_RS18090	COG2203	Gaf domain
HUR98_RS18090	COG5001	Diguanylate cyclase
HUR98_RS18090	COG3706	GGDEF domain
HUR98_RS18100	COG1126	abc transporter atp-binding protein
HUR98_RS18105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUR98_RS18110	COG4215	(ABC) transporter
HUR98_RS18115	COG4160	amino acid transport
HUR98_RS18120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUR98_RS18125	COG5002	protein histidine kinase activity
HUR98_RS18130	COG0745	RESPONSE REGULATOR receiver
HUR98_RS18145	COG1177	transmembrane transport
HUR98_RS18150	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUR98_RS18155	COG3842	ATPase activity
HUR98_RS18160	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUR98_RS18360	COG4695	Portal protein
HUR98_RS18395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUR98_RS18435	COG3344	reverse transcriptase
HUR98_RS18440	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HUR98_RS18445	COG3226	Transcriptional regulator
HUR98_RS18450	COG0738	Major facilitator superfamily
HUR98_RS18455	COG0561	phosphatase activity
HUR98_RS18460	COG2814	Major facilitator Superfamily
HUR98_RS18465	COG0671	phosphoesterase, PA-phosphatase related
HUR98_RS18470	COG1349	DNA-binding transcription factor activity
HUR98_RS18475	COG1686	Belongs to the peptidase S11 family
HUR98_RS18485	COG0625	glutathione transferase activity
HUR98_RS18490	COG2133	pyrroloquinoline quinone binding
HUR98_RS18500	COG2223	nitrite transmembrane transporter activity
HUR98_RS18520	COG0747	negative chemotaxis
HUR98_RS18535	COG0303	'Molybdopterin
HUR98_RS18540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUR98_RS18545	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUR98_RS18550	COG1882	Formate acetyltransferase
HUR98_RS18555	COG0561	phosphatase activity
HUR98_RS18565	COG1609	Transcriptional regulator
HUR98_RS18570	COG2271	Major facilitator Superfamily
HUR98_RS18580	COG0488	(ABC) transporter
HUR98_RS18585	COG2365	Tyrosine phosphatase family
HUR98_RS18590	COG1376	ErfK ybiS ycfS ynhG family protein
HUR98_RS18595	COG2188	Transcriptional regulator
HUR98_RS18600	COG2723	6-phospho-beta-galactosidase activity
HUR98_RS18605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HUR98_RS18610	COG1321	iron dependent repressor
HUR98_RS18620	COG2194	sulfuric ester hydrolase activity
HUR98_RS18625	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HUR98_RS18640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUR98_RS18645	COG0765	amino acid transport
HUR98_RS18650	COG1126	abc transporter atp-binding protein
HUR98_RS18655	COG0668	transmembrane transport
HUR98_RS18665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUR98_RS18675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUR98_RS18685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUR98_RS18690	COG1199	ATP-dependent helicase activity
HUR98_RS18695	COG0513	Belongs to the DEAD box helicase family
HUR98_RS18700	COG3958	Transketolase
HUR98_RS18705	COG3959	Transketolase, thiamine diphosphate binding domain
HUR98_RS18710	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS18715	COG2271	Major facilitator Superfamily
HUR98_RS18725	COG0583	DNA-binding transcription factor activity
HUR98_RS18730	COG1309	transcriptional regulator
HUR98_RS18735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUR98_RS18740	COG1131	(ABC) transporter
HUR98_RS18745	COG0842	Transport permease protein
HUR98_RS18750	COG0842	Transport permease protein
HUR98_RS18760	COG3568	Endonuclease Exonuclease Phosphatase
HUR98_RS18765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUR98_RS18770	COG0392	lysyltransferase activity
HUR98_RS18775	COG0670	Belongs to the BI1 family
HUR98_RS18780	COG0314	molybdopterin synthase activity
HUR98_RS18785	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HUR98_RS18795	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUR98_RS18815	COG0745	RESPONSE REGULATOR receiver
HUR98_RS18820	COG0642	Histidine kinase
HUR98_RS18845	COG2226	methyltransferase
HUR98_RS18860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUR98_RS18865	COG1881	PFAM PEBP family protein
HUR98_RS18905	COG4677	pectinesterase activity
HUR98_RS18940	COG0789	Transcriptional regulator
HUR98_RS18945	COG2200	EAL domain
HUR98_RS18970	COG0561	phosphatase activity
HUR98_RS18975	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HUR98_RS18980	COG4149	molybdate abc transporter
HUR98_RS18985	COG0725	ABC transporter, periplasmic molybdate-binding protein
HUR98_RS18995	COG3585	molybdate ion transport
HUR98_RS18995	COG2005	Transcriptional regulator
HUR98_RS19000	COG1119	ATPase activity
HUR98_RS19010	COG1085	galactose-1-phosphate uridylyltransferase
HUR98_RS19020	COG2017	converts alpha-aldose to the beta-anomer
HUR98_RS19030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUR98_RS19045	COG3201	nicotinamide mononucleotide transporter
HUR98_RS19050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUR98_RS19090	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HUR98_RS19095	COG2885	chlorophyll binding
HUR98_RS19105	COG3064	Membrane
HUR98_RS19110	COG0848	biopolymer transport protein
HUR98_RS19115	COG0811	peptide transport
HUR98_RS19120	COG0824	Thioesterase
HUR98_RS19125	COG3790	cyd operon protein YbgE
HUR98_RS19130	COG4890	Cyd operon protein YbgT
HUR98_RS19135	COG1294	oxidase, subunit
HUR98_RS19140	COG1271	oxidase subunit
HUR98_RS19145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HUR98_RS19155	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUR98_RS19160	COG0567	Dehydrogenase, E1 component
HUR98_RS19165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUR98_RS19170	COG1053	succinate dehydrogenase
HUR98_RS19175	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HUR98_RS19180	COG2009	succinate dehydrogenase
HUR98_RS19215	COG1984	allophanate hydrolase subunit 2
HUR98_RS19220	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HUR98_RS19235	COG0415	Belongs to the DNA photolyase family
HUR98_RS19265	COG2205	protein histidine kinase activity
HUR98_RS19270	COG0745	RESPONSE REGULATOR receiver
HUR98_RS19280	COG0033	Phosphoglucomutase
HUR98_RS19290	COG0596	Alpha beta hydrolase
HUR98_RS19305	COG0735	belongs to the Fur family
HUR98_RS19345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUR98_RS19350	COG1846	Transcriptional regulator
HUR98_RS19350	COG1940	carbohydrate kinase activity
HUR98_RS19355	COG0647	UMP catabolic process
HUR98_RS19360	COG0367	asparagine synthase
HUR98_RS19400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUR98_RS19410	COG1702	phosphate starvation-inducible protein PhoH
HUR98_RS19420	COG4535	Mg2 and Co2 transporter CorC
HUR98_RS19435	COG0765	amino acid transport
HUR98_RS19440	COG0765	amino acid transport
HUR98_RS19445	COG1126	abc transporter atp-binding protein
HUR98_RS19460	COG2888	peptidyl-tyrosine sulfation
HUR98_RS19475	COG1466	dna polymerase III delta subunit
HUR98_RS19490	COG0799	negative regulation of ribosome biogenesis
HUR98_RS19500	COG0768	penicillin binding
HUR98_RS19505	COG0772	Belongs to the SEDS family
HUR98_RS19510	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HUR98_RS19515	COG1686	Belongs to the peptidase S11 family
HUR98_RS19530	COG0583	DNA-binding transcription factor activity
HUR98_RS19545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUR98_RS19565	COG3069	C4-dicarboxylate transmembrane transporter activity
HUR98_RS19570	COG3719	Belongs to the RNase T2 family
HUR98_RS19575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUR98_RS19595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUR98_RS19600	COG0583	DNA-binding transcription factor activity
HUR98_RS19605	COG3969	phosphoadenosine phosphosulfate
HUR98_RS19610	COG1475	DNA binding
HUR98_RS19615	COG0436	Aminotransferase
HUR98_RS19640	COG1129	ABC transporter
HUR98_RS19645	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS19650	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS19660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUR98_RS19675	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HUR98_RS19685	COG0402	S-adenosylhomocysteine deaminase activity
HUR98_RS19695	COG0483	inositol monophosphate 1-phosphatase activity
HUR98_RS19700	COG2271	Major facilitator Superfamily
HUR98_RS19730	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS19735	COG1129	ABC transporter
HUR98_RS19740	COG0371	Dehydrogenase
HUR98_RS19745	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS19760	COG2879	small protein
HUR98_RS19765	COG1966	Carbon starvation protein
HUR98_RS19775	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS19780	COG1535	isochorismatase
HUR98_RS19780	COG3433	isochorismatase activity
HUR98_RS19785	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUR98_RS19790	COG1169	isochorismate synthase
HUR98_RS19795	COG4592	Periplasmic binding protein
HUR98_RS19805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUR98_RS19810	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUR98_RS19815	COG1120	ATPase activity
HUR98_RS19820	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUR98_RS19820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUR98_RS19825	COG3251	PFAM MbtH domain protein
HUR98_RS19830	COG2382	esterase
HUR98_RS19835	COG4771	TonB-dependent receptor
HUR98_RS19840	COG2977	Belongs to the P-Pant transferase superfamily
HUR98_RS19845	COG3958	Transketolase
HUR98_RS19850	COG3959	Transketolase, thiamine diphosphate binding domain
HUR98_RS19855	COG2390	Transcriptional regulator
HUR98_RS19860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUR98_RS19865	COG1879	ABC-type sugar transport system periplasmic component
HUR98_RS19875	COG1129	ABC transporter
HUR98_RS19880	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS19890	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS19900	COG0583	DNA-binding transcription factor activity
HUR98_RS19905	COG0668	transmembrane transport
HUR98_RS19915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUR98_RS19940	COG0747	negative chemotaxis
HUR98_RS19945	COG0601	transmembrane transport
HUR98_RS19950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUR98_RS19955	COG0444	Belongs to the ABC transporter superfamily
HUR98_RS19960	COG4608	Belongs to the ABC transporter superfamily
HUR98_RS19970	COG4221	oxidoreductase activity
HUR98_RS19980	COG4215	(ABC) transporter
HUR98_RS19985	COG0765	amino acid transport
HUR98_RS19990	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HUR98_RS20005	COG0697	spore germination
HUR98_RS20015	COG3698	Phosphodiester glycosidase
HUR98_RS20060	COG2315	Protein conserved in bacteria
HUR98_RS20065	COG0778	Nitroreductase
HUR98_RS20075	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUR98_RS20085	COG3716	PTS system mannose fructose sorbose family IID component
HUR98_RS20090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUR98_RS20095	COG2222	sugar isomerase
HUR98_RS20100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HUR98_RS20100	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HUR98_RS20115	COG0477	Major facilitator Superfamily
HUR98_RS20120	COG0668	transmembrane transport
HUR98_RS20150	COG3188	usher protein
HUR98_RS20165	COG2771	luxR family
HUR98_RS20175	COG0673	inositol 2-dehydrogenase activity
HUR98_RS20185	COG2211	Major facilitator Superfamily
HUR98_RS20190	COG1113	amino acid transport
HUR98_RS20205	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS20210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUR98_RS20220	COG0531	amino acid
HUR98_RS20265	COG0667	Aldo Keto reductase
HUR98_RS20270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUR98_RS20275	COG1473	amidohydrolase
HUR98_RS20305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUR98_RS20310	COG1120	ATPase activity
HUR98_RS20315	COG1566	PFAM secretion protein HlyD family protein
HUR98_RS20360	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS20365	COG1129	ABC transporter
HUR98_RS20380	COG0673	inositol 2-dehydrogenase activity
HUR98_RS20410	COG3104	oligopeptide transport
HUR98_RS20415	COG1982	Orn Lys Arg decarboxylase major
HUR98_RS20420	COG0531	amino acid
HUR98_RS20425	COG3710	Transcriptional regulator
HUR98_RS20435	COG1560	Kdo2-lipid A biosynthetic process
HUR98_RS20450	COG3188	usher protein
HUR98_RS20455	COG3121	Chaperone
HUR98_RS20460	COG3539	Fimbrial protein
HUR98_RS20510	COG2501	S4 domain
HUR98_RS20520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUR98_RS20535	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUR98_RS20540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HUR98_RS20560	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HUR98_RS20565	COG4181	ATPase activity
HUR98_RS20570	COG2755	lipolytic protein G-D-S-L family
HUR98_RS20575	COG0300	oxidoreductase activity
HUR98_RS20580	COG3118	belongs to the thioredoxin family
HUR98_RS20585	COG0390	transport system, permease component
HUR98_RS20590	COG4619	ABC transporter
HUR98_RS20595	COG0330	HflC and HflK could
HUR98_RS20600	COG1585	Membrane protein implicated in regulation of membrane protease activity
HUR98_RS20615	COG3735	TraB family
HUR98_RS20620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUR98_RS20630	COG2223	nitrite transmembrane transporter activity
HUR98_RS20635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUR98_RS20635	COG4651	solute:proton antiporter activity
HUR98_RS20640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUR98_RS20680	COG2832	Protein of unknown function (DUF454)
HUR98_RS20685	COG3923	Primosomal replication protein n
HUR98_RS20695	COG5464	transposase or invertase
HUR98_RS20700	COG3264	Mechanosensitive ion channel
HUR98_RS20700	COG1196	nuclear chromosome segregation
HUR98_RS20720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUR98_RS20725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUR98_RS20740	COG0110	maltose O-acetyltransferase activity
HUR98_RS20790	COG1874	Beta-galactosidase
HUR98_RS20795	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HUR98_RS20800	COG3833	ABC-type maltose transport systems, permease component
HUR98_RS20805	COG1175	transmembrane transport
HUR98_RS20810	COG2182	Extracellular solute-binding protein
HUR98_RS20820	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HUR98_RS20835	COG2364	Membrane
HUR98_RS20865	COG3695	enzyme binding
HUR98_RS20870	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HUR98_RS20875	COG1946	Acyl-CoA thioesterase
HUR98_RS20880	COG0004	ammonium transporteR
HUR98_RS20885	COG0347	Belongs to the P(II) protein family
HUR98_RS20890	COG1132	(ABC) transporter
HUR98_RS20895	COG1132	(ABC) transporter
HUR98_RS20900	COG1522	sequence-specific DNA binding
HUR98_RS20915	COG4533	DNA binding
HUR98_RS20925	COG0824	Thioesterase
HUR98_RS20930	COG1555	photosystem II stabilization
HUR98_RS20935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUR98_RS20940	COG0776	regulation of translation
HUR98_RS20945	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUR98_RS20965	COG0271	Belongs to the BolA IbaG family
HUR98_RS20970	COG3056	Lipoprotein
HUR98_RS20975	COG2223	nitrite transmembrane transporter activity
HUR98_RS20980	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUR98_RS20985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUR98_RS20990	COG1845	cytochrome c oxidase, subunit III
HUR98_RS20995	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HUR98_RS21010	COG1414	Transcriptional regulator
HUR98_RS21015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUR98_RS21020	COG1053	succinate dehydrogenase
HUR98_RS21030	COG1053	succinate dehydrogenase
HUR98_RS21045	COG0673	inositol 2-dehydrogenase activity
HUR98_RS21050	COG2814	Major facilitator Superfamily
HUR98_RS21060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUR98_RS21065	COG0693	protein deglycase activity
HUR98_RS21085	COG0142	geranyltranstransferase activity
HUR98_RS21095	COG0667	Aldo Keto reductase
HUR98_RS21100	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HUR98_RS21120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUR98_RS21120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUR98_RS21130	COG4238	major outer membrane lipoprotein
HUR98_RS21150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUR98_RS21155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUR98_RS21160	COG1862	Preprotein translocase
HUR98_RS21185	COG0450	alkyl hydroperoxide reductase
HUR98_RS21195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS21210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUR98_RS21220	COG1228	amidohydrolase
HUR98_RS21230	COG1335	isochorismatase
HUR98_RS21235	COG0583	DNA-binding transcription factor activity
HUR98_RS21240	COG0366	Alpha amylase catalytic
HUR98_RS21265	COG0420	3'-5' exonuclease activity
HUR98_RS21270	COG0419	ATPase involved in DNA repair
HUR98_RS21275	COG1940	carbohydrate kinase activity
HUR98_RS21290	COG4126	flavin adenine dinucleotide binding
HUR98_RS21300	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUR98_RS21305	COG3416	Protein conserved in bacteria
HUR98_RS21315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUR98_RS21325	COG1785	Belongs to the alkaline phosphatase family
HUR98_RS21365	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HUR98_RS21370	COG1335	isochorismatase
HUR98_RS21375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUR98_RS21380	COG0113	porphobilinogen synthase activity
HUR98_RS21390	COG2175	clavaminate synthase activity
HUR98_RS21395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUR98_RS21400	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HUR98_RS21405	COG4521	taurine ABC transporter
HUR98_RS21410	COG2040	homocysteine
HUR98_RS21415	COG0833	amino acid
HUR98_RS21430	COG4303	Ethanolamine ammonia lyase large subunit
HUR98_RS21435	COG4302	ethanolamine ammonia-lyase activity
HUR98_RS21475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUR98_RS21480	COG1126	abc transporter atp-binding protein
HUR98_RS21485	COG0765	amino acid transport
HUR98_RS21490	COG0765	amino acid transport
HUR98_RS21505	COG3188	usher protein
HUR98_RS21535	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HUR98_RS21545	COG3639	organic phosphonate transmembrane transporter activity
HUR98_RS21565	COG0791	NLP P60 protein
HUR98_RS21590	COG0582	viral genome integration into host DNA
HUR98_RS21595	COG1192	Involved in chromosome partitioning
HUR98_RS21655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUR98_RS21660	COG0022	dehydrogenase e1 component
HUR98_RS21665	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUR98_RS21670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUR98_RS21690	COG1070	Carbohydrate kinase
HUR98_RS21695	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS21700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUR98_RS21705	COG3775	system Galactitol-specific IIC component
HUR98_RS21710	COG0625	glutathione transferase activity
HUR98_RS21715	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HUR98_RS21730	COG0579	oxidoreductase
HUR98_RS21735	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS21740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUR98_RS21745	COG1113	amino acid transport
HUR98_RS21750	COG1802	Transcriptional regulator
HUR98_RS21770	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUR98_RS21775	COG0454	-acetyltransferase
HUR98_RS21790	COG2991	Protein conserved in bacteria
HUR98_RS21805	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HUR98_RS21810	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HUR98_RS21825	COG3034	peptidoglycan biosynthetic process
HUR98_RS21830	COG0121	glutamine amidotransferase
HUR98_RS21840	COG1960	acyl-CoA dehydrogenase activity
HUR98_RS21845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUR98_RS21855	COG0583	DNA-binding transcription factor activity
HUR98_RS21865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUR98_RS21875	COG2226	methyltransferase
HUR98_RS21885	COG1388	LysM domain
HUR98_RS21885	COG0741	lytic transglycosylase activity
HUR98_RS21890	COG2226	methyltransferase
HUR98_RS21900	COG2814	Major facilitator Superfamily
HUR98_RS21905	COG0583	DNA-binding transcription factor activity
HUR98_RS21910	COG0656	L-ascorbic acid biosynthetic process
HUR98_RS21945	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HUR98_RS21955	COG2011	ABC-type metal ion transport system permease component
HUR98_RS21960	COG1464	Belongs to the NlpA lipoprotein family
HUR98_RS21970	COG1720	tRNA m6t6A37 methyltransferase activity
HUR98_RS21980	COG0791	NLP P60 protein
HUR98_RS21985	COG3015	lipoprotein NlpE involved in copper resistance
HUR98_RS21990	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUR98_RS22005	COG4568	rho-dependent transcription termination
HUR98_RS22015	COG0346	lactoylglutathione lyase activity
HUR98_RS22060	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HUR98_RS22070	COG0750	zinc metalloprotease
HUR98_RS22075	COG0575	Belongs to the CDS family
HUR98_RS22085	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUR98_RS22110	COG0024	Methionine aminopeptidase
HUR98_RS22115	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUR98_RS22130	COG3835	regulator
HUR98_RS22135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUR98_RS22155	COG2860	membrane
HUR98_RS22175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUR98_RS22180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUR98_RS22185	COG1120	ATPase activity
HUR98_RS22195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUR98_RS22290	COG1643	Atp-dependent helicase
HUR98_RS22295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HUR98_RS22315	COG0617	tRNA 3'-terminal CCA addition
HUR98_RS22320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HUR98_RS22340	COG0726	polysaccharide deacetylase
HUR98_RS22345	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS22350	COG0842	Transport permease protein
HUR98_RS22355	COG1131	(ABC) transporter
HUR98_RS22360	COG0288	reversible hydration of carbon dioxide
HUR98_RS22375	COG4993	Dehydrogenase
HUR98_RS22380	COG2132	Multicopper oxidase
HUR98_RS22430	COG3064	Membrane
HUR98_RS22445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUR98_RS22450	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUR98_RS22455	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUR98_RS22460	COG2186	Transcriptional regulator
HUR98_RS22465	COG1113	amino acid transport
HUR98_RS22470	COG2211	Major facilitator Superfamily
HUR98_RS22475	COG3940	Belongs to the glycosyl hydrolase 43 family
HUR98_RS22480	COG3725	Membrane protein required for beta-lactamase induction
HUR98_RS22485	COG3023	N-Acetylmuramoyl-L-alanine amidase
HUR98_RS22495	COG4969	Belongs to the N-Me-Phe pilin family
HUR98_RS22500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUR98_RS22505	COG1459	type II secretion system
HUR98_RS22530	COG0494	nUDIX hydrolase
HUR98_RS22550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUR98_RS22555	COG0849	cell division
HUR98_RS22580	COG0772	Belongs to the SEDS family
HUR98_RS22595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUR98_RS22600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUR98_RS22605	COG0768	penicillin binding
HUR98_RS22625	COG1609	Transcriptional regulator
HUR98_RS22635	COG0028	Belongs to the TPP enzyme family
HUR98_RS22680	COG0738	Major facilitator superfamily
HUR98_RS22690	COG0583	DNA-binding transcription factor activity
HUR98_RS22695	COG2271	Major facilitator Superfamily
HUR98_RS22700	COG2814	Major facilitator Superfamily
HUR98_RS22720	COG1178	ABC-type Fe3 transport system permease component
HUR98_RS22730	COG0586	Pfam SNARE associated Golgi protein
HUR98_RS22750	COG0235	Class ii aldolase
HUR98_RS22755	COG0417	DNA replication proofreading
HUR98_RS22765	COG0564	pseudouridine synthase activity
HUR98_RS22775	COG3493	citrate carrier protein
HUR98_RS22790	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HUR98_RS22795	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HUR98_RS22805	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HUR98_RS22850	COG0505	Belongs to the CarA family
HUR98_RS22915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUR98_RS22940	COG1047	Peptidyl-prolyl cis-trans
HUR98_RS22955	COG0196	riboflavin kinase activity
HUR98_RS22970	COG0583	DNA-binding transcription factor activity
HUR98_RS22995	COG4735	regulation of single-species biofilm formation
HUR98_RS23000	COG1584	GPR1 FUN34 yaaH family protein
HUR98_RS23005	COG0477	Major facilitator Superfamily
HUR98_RS23010	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUR98_RS23015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUR98_RS23020	COG1115	amino acid carrier protein
HUR98_RS23035	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUR98_RS23045	COG0527	aspartate kinase activity
HUR98_RS23045	COG0460	homoserine dehydrogenase
HUR98_RS23055	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HUR98_RS23065	COG0745	RESPONSE REGULATOR receiver
HUR98_RS23070	COG4452	Inner membrane protein CreD
HUR98_RS23075	COG2205	protein histidine kinase activity
HUR98_RS23080	COG0745	RESPONSE REGULATOR receiver
HUR98_RS23085	COG3045	CreA protein
HUR98_RS23090	COG2207	Transcriptional regulator
HUR98_RS23090	COG3708	Transcriptional regulator
HUR98_RS23110	COG0741	lytic transglycosylase activity
HUR98_RS23115	COG0488	(ABC) transporter
HUR98_RS23125	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HUR98_RS23130	COG0560	Phosphoserine phosphatase
HUR98_RS23135	COG3726	membrane protein affecting hemolysin expression
HUR98_RS23165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUR98_RS23170	COG0084	hydrolase, TatD family'
HUR98_RS23175	COG4667	esterase of the alpha-beta hydrolase superfamily
HUR98_RS23185	COG2823	Periplasmic or secreted lipoprotein
HUR98_RS23195	COG1011	Hydrolase
HUR98_RS23200	COG0456	acetyltransferase
HUR98_RS23205	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HUR98_RS23240	COG3706	GGDEF domain
HUR98_RS23245	COG4114	ferric iron reductase
HUR98_RS23250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS23250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS23255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUR98_RS23260	COG2197	response regulator
HUR98_RS23265	COG2197	response regulator
HUR98_RS23280	COG2966	Psort location CytoplasmicMembrane, score
HUR98_RS23295	COG1484	DNA-dependent DNA replication
HUR98_RS23310	COG5464	transposase or invertase
HUR98_RS23320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUR98_RS23325	COG3716	PTS system mannose fructose sorbose family IID component
HUR98_RS23330	COG3715	PTS system
HUR98_RS23345	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HUR98_RS23345	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HUR98_RS23355	COG1063	alcohol dehydrogenase
HUR98_RS23360	COG1802	Transcriptional regulator
HUR98_RS23365	COG2271	Major facilitator Superfamily
HUR98_RS23370	COG1214	PFAM Peptidase M22, glycoprotease
HUR98_RS23370	COG0456	acetyltransferase
HUR98_RS23380	COG1737	Transcriptional regulator
HUR98_RS23385	COG0800	Aldolase
HUR98_RS23390	COG3734	2-keto-3-deoxy-galactonokinase
HUR98_RS23405	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUR98_RS23435	COG1846	Transcriptional regulator
HUR98_RS23445	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUR98_RS23455	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS23460	COG3384	dioxygenase
HUR98_RS23470	COG3971	2-oxopent-4-enoate hydratase activity
HUR98_RS23490	COG2368	4-hydroxyphenylacetate
HUR98_RS23495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUR98_RS23525	COG1966	Carbon starvation protein
HUR98_RS23530	COG2879	small protein
HUR98_RS23535	COG0523	cobalamin synthesis protein
HUR98_RS23545	COG1012	belongs to the aldehyde dehydrogenase family
HUR98_RS23550	COG5464	transposase or invertase
HUR98_RS23555	COG2207	Transcriptional regulator
HUR98_RS23555	COG1917	Cupin 2, conserved barrel domain protein
HUR98_RS23565	COG2733	membrane
HUR98_RS23580	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HUR98_RS23585	COG1924	4 iron, 4 sulfur cluster binding
HUR98_RS23600	COG1566	PFAM secretion protein HlyD family protein
HUR98_RS23610	COG5457	Domain of unknown function (DUF1127)
HUR98_RS23615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUR98_RS23625	COG0583	DNA-binding transcription factor activity
HUR98_RS23630	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUR98_RS23640	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS23645	COG1129	ABC transporter
HUR98_RS23650	COG1879	ABC-type sugar transport system periplasmic component
HUR98_RS23660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUR98_RS23665	COG1129	ABC transporter
HUR98_RS23665	COG0842	Transport permease protein
HUR98_RS23670	COG0842	Transport permease protein
HUR98_RS23700	COG2850	peptidyl-arginine hydroxylation
HUR98_RS23715	COG5002	protein histidine kinase activity
HUR98_RS23720	COG0745	RESPONSE REGULATOR receiver
HUR98_RS23725	COG1538	Outer membrane efflux protein
HUR98_RS23730	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUR98_RS23735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUR98_RS23740	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUR98_RS23750	COG3040	lipid binding
HUR98_RS23755	COG0789	Transcriptional regulator
HUR98_RS23765	COG0300	oxidoreductase activity
HUR98_RS23780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUR98_RS23800	COG3272	Protein of unknown function (DUF1722)
HUR98_RS23805	COG4580	involved in the transport of maltose and maltodextrins
HUR98_RS23815	COG2211	Major facilitator Superfamily
HUR98_RS23820	COG3507	Belongs to the glycosyl hydrolase 43 family
HUR98_RS23920	COG3039	Transposase
HUR98_RS23925	COG0582	viral genome integration into host DNA
HUR98_RS23935	COG0288	reversible hydration of carbon dioxide
HUR98_RS23940	COG0659	secondary active sulfate transmembrane transporter activity
HUR98_RS23945	COG1064	alcohol dehydrogenase
HUR98_RS23950	COG1175	transmembrane transport
HUR98_RS23955	COG0395	ABC-type sugar transport system, permease component
HUR98_RS23960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUR98_RS23965	COG3842	ATPase activity
HUR98_RS23970	COG1653	transport
HUR98_RS23980	COG1082	Xylose isomerase domain protein TIM barrel
HUR98_RS23990	COG3962	Belongs to the TPP enzyme family
HUR98_RS23995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUR98_RS24000	COG1737	Transcriptional regulator
HUR98_RS24000	COG0837	glucose binding
HUR98_RS24005	COG3718	enzyme involved in inositol metabolism
HUR98_RS24020	COG0433	COG0433 Predicted ATPase
HUR98_RS24025	COG0795	lipopolysaccharide-transporting ATPase activity
HUR98_RS24030	COG0795	lipopolysaccharide-transporting ATPase activity
HUR98_RS24040	COG2927	DNA polymerase III (CHI subunit)
HUR98_RS24045	COG0525	valine-tRNA ligase activity
HUR98_RS24070	COG2188	Transcriptional regulator
HUR98_RS24075	COG1288	antiporter activity
HUR98_RS24080	COG1228	amidohydrolase
HUR98_RS24085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUR98_RS24090	COG2222	sugar isomerase
HUR98_RS24095	COG2731	YhcH YjgK YiaL family protein
HUR98_RS24130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUR98_RS24130	COG1263	PTS System
HUR98_RS24135	COG0366	Alpha amylase catalytic
HUR98_RS24140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUR98_RS24145	COG1486	melibiose metabolic process
HUR98_RS24170	COG0602	queuosine metabolic process
HUR98_RS24175	COG2026	Addiction module toxin, RelE StbE family
HUR98_RS24180	COG3077	Addiction module antitoxin, RelB DinJ family
HUR98_RS24185	COG3711	transcriptional antiterminator
HUR98_RS24185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUR98_RS24190	COG2706	6-phosphogluconolactonase activity
HUR98_RS24205	COG3964	amidohydrolase
HUR98_RS24245	COG0312	modulator of DNA gyrase
HUR98_RS24270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUR98_RS24280	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS24285	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS24290	COG1129	ABC transporter
HUR98_RS24295	COG1879	ABC-type sugar transport system periplasmic component
HUR98_RS24315	COG2105	PFAM AIG2 family protein
HUR98_RS24320	COG2911	Protein conserved in bacteria
HUR98_RS24325	COG0729	surface antigen
HUR98_RS24335	COG1253	flavin adenine dinucleotide binding
HUR98_RS24350	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HUR98_RS24365	COG1733	regulation of RNA biosynthetic process
HUR98_RS24370	COG0702	epimerase
HUR98_RS24380	COG0697	spore germination
HUR98_RS24390	COG1113	amino acid transport
HUR98_RS24395	COG0545	Peptidyl-prolyl cis-trans isomerase
HUR98_RS24400	COG3061	Opacity-associated protein A
HUR98_RS24410	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUR98_RS24415	COG2965	DNA replication, synthesis of RNA primer
HUR98_RS24475	COG1073	alpha beta
HUR98_RS24480	COG3650	response to hydrogen peroxide
HUR98_RS24490	COG1960	acyl-CoA dehydrogenase activity
HUR98_RS24495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUR98_RS24500	COG0557	exoribonuclease II activity
HUR98_RS24515	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HUR98_RS24525	COG0330	HflC and HflK could
HUR98_RS24530	COG0330	HflC and HflK could
HUR98_RS24535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUR98_RS24555	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUR98_RS24560	COG0802	atpase or kinase
HUR98_RS24565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HUR98_RS24565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HUR98_RS24570	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HUR98_RS24590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUR98_RS24610	COG1511	domain protein
HUR98_RS24610	COG3264	Mechanosensitive ion channel
HUR98_RS24625	COG1053	succinate dehydrogenase
HUR98_RS24630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUR98_RS24650	COG2076	Multidrug Resistance protein
HUR98_RS24655	COG5510	response to toxic substance
HUR98_RS24670	COG1509	lysine 2,3-aminomutase activity
HUR98_RS24740	COG0531	amino acid
HUR98_RS24745	COG3030	protein affecting phage T7 exclusion by the F plasmid
HUR98_RS24750	COG1027	Aspartate ammonia-lyase
HUR98_RS24755	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HUR98_RS24770	COG1309	transcriptional regulator
HUR98_RS24800	COG0457	Tetratricopeptide repeat
HUR98_RS24805	COG0726	polysaccharide deacetylase
HUR98_RS24805	COG1649	PFAM Uncharacterised BCR, COG1649
HUR98_RS24810	COG1215	transferase activity, transferring glycosyl groups
HUR98_RS24825	COG0861	Integral membrane protein TerC family
HUR98_RS24870	COG1486	melibiose metabolic process
HUR98_RS24875	COG2169	Transcriptional regulator
HUR98_RS24885	COG2824	Alkylphosphonate utilization operon protein PhnA
HUR98_RS24890	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HUR98_RS24895	COG2188	Transcriptional regulator
HUR98_RS24900	COG3624	Phosphonate C-P lyase system protein PhnG
HUR98_RS24905	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HUR98_RS24910	COG3626	phosphonate metabolism
HUR98_RS24915	COG3627	carbon phosphorus lyase activity
HUR98_RS24920	COG4107	phosphonate C-P lyase system protein PhnK
HUR98_RS24925	COG4778	phosphonate C-P lyase system protein PhnL
HUR98_RS24930	COG3454	Phosphonate metabolism
HUR98_RS24940	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HUR98_RS24950	COG0784	Response regulator, receiver
HUR98_RS24950	COG4191	Histidine kinase
HUR98_RS24955	COG1129	ABC transporter
HUR98_RS24960	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS24995	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HUR98_RS25000	COG1301	dicarboxylic acid transport
HUR98_RS25010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUR98_RS25015	COG3162	membrane
HUR98_RS25045	COG3539	Fimbrial protein
HUR98_RS25050	COG1346	cytolysis
HUR98_RS25055	COG1380	Effector of murein hydrolase LrgA
HUR98_RS25060	COG0583	DNA-binding transcription factor activity
HUR98_RS25065	COG0025	NhaP-type Na H and K H
HUR98_RS25070	COG2252	PERMEase
HUR98_RS25075	COG0625	glutathione transferase activity
HUR98_RS25080	COG0789	Transcriptional regulator
HUR98_RS25090	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HUR98_RS25120	COG1234	tRNA 3'-trailer cleavage
HUR98_RS25125	COG1609	Transcriptional regulator
HUR98_RS25130	COG0483	inositol monophosphate 1-phosphatase activity
HUR98_RS25140	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUR98_RS25160	COG4771	TonB-dependent receptor
HUR98_RS25165	COG0741	lytic transglycosylase activity
HUR98_RS25180	COG2315	Protein conserved in bacteria
HUR98_RS25185	COG0432	Pfam Uncharacterised protein family UPF0047
HUR98_RS25200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUR98_RS25205	COG0305	Participates in initiation and elongation during chromosome replication
HUR98_RS25220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUR98_RS25230	COG0735	belongs to the Fur family
HUR98_RS25235	COG3237	CsbD-like
HUR98_RS25245	COG0534	Mate efflux family protein
HUR98_RS25255	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HUR98_RS25325	COG0251	oxidation-reduction process
HUR98_RS25335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUR98_RS25345	COG0527	aspartate kinase activity
HUR98_RS25400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUR98_RS25430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HUR98_RS25440	COG0456	acetyltransferase
HUR98_RS25470	COG0151	Belongs to the GarS family
HUR98_RS25480	COG4191	Histidine kinase
HUR98_RS25485	COG3678	ATP-independent chaperone mediated protein folding
HUR98_RS25520	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HUR98_RS25535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUR98_RS25540	COG2104	thiamine diphosphate biosynthetic process
HUR98_RS25555	COG3706	GGDEF domain
HUR98_RS25565	COG1447	Phosphotransferase system cellobiose-specific component IIA
HUR98_RS25570	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HUR98_RS25605	COG0250	Participates in transcription elongation, termination and antitermination
HUR98_RS25650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUR98_RS25680	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HUR98_RS25690	COG1739	Uncharacterized protein family UPF0029
HUR98_RS25730	COG0805	protein transport
HUR98_RS25750	COG3165	ubiquinone biosynthetic process from chorismate
HUR98_RS25780	COG0583	DNA-binding transcription factor activity
HUR98_RS25785	COG0697	spore germination
HUR98_RS25790	COG0561	phosphatase activity
HUR98_RS25795	COG2267	carboxylic ester hydrolase activity
HUR98_RS25800	COG1280	lysine exporter protein (LysE YggA)
HUR98_RS25810	COG1280	lysine exporter protein (LysE YggA)
HUR98_RS25840	COG0210	DNA helicase
HUR98_RS25845	COG1011	Hydrolase
HUR98_RS25875	COG3072	Adenylate cyclase
HUR98_RS25890	COG2959	enzyme of heme biosynthesis
HUR98_RS25895	COG3071	HemY protein
HUR98_RS25940	COG2244	polysaccharide biosynthetic process
HUR98_RS25945	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUR98_RS25950	COG0456	acetyltransferase
HUR98_RS25955	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HUR98_RS25960	COG1088	dTDP-glucose 4,6-dehydratase activity
HUR98_RS25965	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HUR98_RS25970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUR98_RS25980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUR98_RS25985	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HUR98_RS25990	COG3118	belongs to the thioredoxin family
HUR98_RS26015	COG1811	Na channel or pump
HUR98_RS26025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUR98_RS26030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUR98_RS26040	COG0583	DNA-binding transcription factor activity
HUR98_RS26045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUR98_RS26060	COG3978	acetolactate synthase activity
HUR98_RS26080	COG3085	chromosome segregation
HUR98_RS26155	COG0583	DNA-binding transcription factor activity
HUR98_RS26170	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUR98_RS26185	COG3443	Belongs to the bacterial solute-binding protein 9 family
HUR98_RS26190	COG2207	Transcriptional regulator
HUR98_RS26200	COG0371	Dehydrogenase
HUR98_RS26205	COG0697	spore germination
HUR98_RS26215	COG0583	DNA-binding transcription factor activity
HUR98_RS26225	COG0737	Belongs to the 5'-nucleotidase family
HUR98_RS26235	COG0460	homoserine dehydrogenase
HUR98_RS26235	COG0527	aspartate kinase activity
HUR98_RS26240	COG0626	cystathionine gamma-synthase activity
HUR98_RS26255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUR98_RS26260	COG1609	Transcriptional regulator
HUR98_RS26265	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HUR98_RS26280	COG1575	Belongs to the MenA family. Type 1 subfamily
HUR98_RS26300	COG3678	ATP-independent chaperone mediated protein folding
HUR98_RS26305	COG0745	RESPONSE REGULATOR receiver
HUR98_RS26310	COG2205	protein histidine kinase activity
HUR98_RS26315	COG2258	MOSC domain
HUR98_RS26320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUR98_RS26360	COG1129	ABC transporter
HUR98_RS26365	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS26370	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS26375	COG1454	alcohol dehydrogenase
HUR98_RS26385	COG2211	Major facilitator Superfamily
HUR98_RS26445	COG0205	6-phosphofructokinase activity
HUR98_RS26465	COG0437	4 iron, 4 sulfur cluster binding
HUR98_RS26470	COG2864	formate dehydrogenase
HUR98_RS26485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HUR98_RS26495	COG0456	acetyltransferase
HUR98_RS26510	COG1011	Hydrolase
HUR98_RS26525	COG3852	Histidine kinase
HUR98_RS26540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUR98_RS26560	COG0204	Acyl-transferase
HUR98_RS26570	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HUR98_RS26575	COG3084	Protein conserved in bacteria
HUR98_RS26585	COG1763	Mo-molybdopterin cofactor biosynthetic process
HUR98_RS26610	COG2186	Transcriptional regulator
HUR98_RS26615	COG0477	Major facilitator Superfamily
HUR98_RS26620	COG1609	Transcriptional regulator
HUR98_RS26625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUR98_RS26635	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUR98_RS26640	COG1129	ABC transporter
HUR98_RS26670	COG1522	sequence-specific DNA binding
HUR98_RS26675	COG0716	FMN binding
HUR98_RS26690	COG3312	ion transport
HUR98_RS26740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUR98_RS26745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUR98_RS26750	COG0573	inorganic phosphate transmembrane transporter activity
HUR98_RS26755	COG0581	inorganic phosphate transmembrane transporter activity
HUR98_RS26760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUR98_RS26765	COG0704	Plays a role in the regulation of phosphate uptake
HUR98_RS26785	COG2382	esterase
HUR98_RS26790	COG0363	glucosamine-6-phosphate deaminase activity
HUR98_RS26795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUR98_RS26800	COG2252	PERMEase
HUR98_RS26805	COG0431	NADPH-dependent FMN reductase
HUR98_RS26810	COG2091	lysine biosynthetic process via aminoadipic acid
HUR98_RS26840	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUR98_RS26990	COG0789	Transcriptional regulator
HUR98_RS27005	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUR98_RS27070	COG5499	transcription regulator containing HTH domain
HUR98_RS27075	COG4680	protein conserved in bacteria
HUR98_RS27160	COG0735	belongs to the Fur family
HUR98_RS27165	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUR98_RS27170	COG0523	cobalamin synthesis protein
HUR98_RS27195	COG0523	cobalamin synthesis protein
HUR98_RS27235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUR98_RS27295	COG5654	RES domain protein
HUR98_RS27300	COG5642	Protein of unknown function (DUF2384)
HUR98_RS27350	COG0500	methyltransferase
HUR98_RS27385	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HUR98_RS27395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUR98_RS27415	COG0523	cobalamin synthesis protein
HUR98_RS27585	COG1522	sequence-specific DNA binding
HUR98_RS27600	COG0604	alcohol dehydrogenase
HUR98_RS27600	COG3321	synthase
HUR98_RS27600	COG1028	Short-chain dehydrogenase reductase Sdr
HUR98_RS27690	COG1358	cellular component organization or biogenesis
HUR98_RS27710	COG4245	von Willebrand factor, type A
HUR98_RS27720	COG4245	von Willebrand factor, type A
HUR98_RS27725	COG4245	von Willebrand factor, type A
HUR98_RS27745	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
HUR98_RS27780	COG2144	transferase activity, transferring acyl groups
HUR98_RS27805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUR98_RS27845	COG3344	reverse transcriptase
HUR98_RS27900	COG4372	Transposase
HUR98_RS27905	COG3436	PFAM IS66 Orf2 family protein
HUR98_RS28115	COG3344	reverse transcriptase
HUR98_RS28210	COG2084	Dehydrogenase
HUR98_RS28215	COG1349	DNA-binding transcription factor activity
HUR98_RS28300	COG5001	Diguanylate cyclase
HUR98_RS28300	COG3300	MHYT domain
HUR98_RS28345	COG2205	protein histidine kinase activity
HUR98_RS28350	COG0745	RESPONSE REGULATOR receiver
HUR98_RS28355	COG1276	copper resistance
HUR98_RS28360	COG2372	response to copper ion
HUR98_RS28365	COG3667	copper resistance
HUR98_RS28370	COG2132	Multicopper oxidase
HUR98_RS28380	COG0739	heme binding
HUR98_RS28410	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUR98_RS28445	COG3706	GGDEF domain
HUR98_RS28515	COG3344	reverse transcriptase
HUR98_RS28595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUR98_RS28745	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HUR98_RS28780	COG0741	lytic transglycosylase activity
HUR98_RS28890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUR98_RS28910	COG3344	reverse transcriptase
HUR98_RS29035	COG0697	spore germination
HUR98_RS29050	COG0768	penicillin binding
HUR98_RS29160	COG2003	Belongs to the UPF0758 family
HUR98_RS29240	COG5002	protein histidine kinase activity
HUR98_RS29240	COG0784	Response regulator, receiver
HUR98_RS29240	COG2198	Histidine kinase
HUR98_RS29285	COG3344	reverse transcriptase
HUR98_RS29295	COG3064	Membrane