locus-tag	class	description
BK002_RS00005	COG0716	FMN binding
BK002_RS00010	COG1522	sequence-specific DNA binding
BK002_RS00040	COG1129	ABC transporter
BK002_RS00045	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS00055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BK002_RS00060	COG1609	Transcriptional regulator
BK002_RS00065	COG0477	Major facilitator Superfamily
BK002_RS00070	COG2186	Transcriptional regulator
BK002_RS00095	COG1763	Mo-molybdopterin cofactor biosynthetic process
BK002_RS00105	COG3084	Protein conserved in bacteria
BK002_RS00110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BK002_RS00120	COG0204	Acyl-transferase
BK002_RS00140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BK002_RS00155	COG3852	Histidine kinase
BK002_RS00170	COG1011	Hydrolase
BK002_RS00185	COG0456	acetyltransferase
BK002_RS00195	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BK002_RS00210	COG2864	formate dehydrogenase
BK002_RS00215	COG0437	4 iron, 4 sulfur cluster binding
BK002_RS00260	COG2211	Major facilitator Superfamily
BK002_RS00270	COG1454	alcohol dehydrogenase
BK002_RS00275	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS00280	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS00285	COG1129	ABC transporter
BK002_RS00325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BK002_RS00330	COG2258	MOSC domain
BK002_RS00335	COG2205	protein histidine kinase activity
BK002_RS00340	COG0745	RESPONSE REGULATOR receiver
BK002_RS00345	COG3678	ATP-independent chaperone mediated protein folding
BK002_RS00365	COG1575	Belongs to the MenA family. Type 1 subfamily
BK002_RS00380	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BK002_RS00385	COG1609	Transcriptional regulator
BK002_RS00390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BK002_RS00405	COG0626	cystathionine gamma-synthase activity
BK002_RS00410	COG0460	homoserine dehydrogenase
BK002_RS00410	COG0527	aspartate kinase activity
BK002_RS00420	COG0737	Belongs to the 5'-nucleotidase family
BK002_RS00430	COG0583	DNA-binding transcription factor activity
BK002_RS00440	COG0697	spore germination
BK002_RS00445	COG0371	Dehydrogenase
BK002_RS00455	COG2207	Transcriptional regulator
BK002_RS00460	COG3443	Belongs to the bacterial solute-binding protein 9 family
BK002_RS00475	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BK002_RS00490	COG0583	DNA-binding transcription factor activity
BK002_RS00565	COG3085	chromosome segregation
BK002_RS00590	COG3978	acetolactate synthase activity
BK002_RS00605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BK002_RS00610	COG0583	DNA-binding transcription factor activity
BK002_RS00620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BK002_RS00625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BK002_RS00635	COG1811	Na channel or pump
BK002_RS00660	COG3118	belongs to the thioredoxin family
BK002_RS00665	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BK002_RS00670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BK002_RS00680	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BK002_RS00685	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BK002_RS00690	COG1088	dTDP-glucose 4,6-dehydratase activity
BK002_RS00695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BK002_RS00700	COG0456	acetyltransferase
BK002_RS00705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BK002_RS00710	COG2244	polysaccharide biosynthetic process
BK002_RS00755	COG3071	HemY protein
BK002_RS00760	COG2959	enzyme of heme biosynthesis
BK002_RS00775	COG3072	Adenylate cyclase
BK002_RS00805	COG1011	Hydrolase
BK002_RS00810	COG0210	DNA helicase
BK002_RS00840	COG1280	lysine exporter protein (LysE YggA)
BK002_RS00850	COG1280	lysine exporter protein (LysE YggA)
BK002_RS00855	COG2267	carboxylic ester hydrolase activity
BK002_RS00860	COG0561	phosphatase activity
BK002_RS00865	COG0697	spore germination
BK002_RS00870	COG0583	DNA-binding transcription factor activity
BK002_RS00900	COG3165	ubiquinone biosynthetic process from chorismate
BK002_RS00920	COG0805	protein transport
BK002_RS00960	COG1739	Uncharacterized protein family UPF0029
BK002_RS00970	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BK002_RS01000	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BK002_RS01045	COG0250	Participates in transcription elongation, termination and antitermination
BK002_RS01080	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BK002_RS01085	COG1447	Phosphotransferase system cellobiose-specific component IIA
BK002_RS01095	COG3706	GGDEF domain
BK002_RS01110	COG2104	thiamine diphosphate biosynthetic process
BK002_RS01115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BK002_RS01130	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BK002_RS01165	COG3678	ATP-independent chaperone mediated protein folding
BK002_RS01170	COG4191	Histidine kinase
BK002_RS01180	COG0151	Belongs to the GarS family
BK002_RS01210	COG0456	acetyltransferase
BK002_RS01220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BK002_RS01270	COG0527	aspartate kinase activity
BK002_RS01280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BK002_RS01290	COG0251	oxidation-reduction process
BK002_RS01360	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BK002_RS01370	COG0534	Mate efflux family protein
BK002_RS01380	COG3237	CsbD-like
BK002_RS01385	COG0735	belongs to the Fur family
BK002_RS01395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BK002_RS01410	COG0305	Participates in initiation and elongation during chromosome replication
BK002_RS01415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BK002_RS01430	COG0432	Pfam Uncharacterised protein family UPF0047
BK002_RS01435	COG2315	Protein conserved in bacteria
BK002_RS01450	COG0741	lytic transglycosylase activity
BK002_RS01455	COG4771	TonB-dependent receptor
BK002_RS01475	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BK002_RS01485	COG0483	inositol monophosphate 1-phosphatase activity
BK002_RS01490	COG1609	Transcriptional regulator
BK002_RS01495	COG1234	tRNA 3'-trailer cleavage
BK002_RS01525	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BK002_RS01535	COG0789	Transcriptional regulator
BK002_RS01540	COG0625	glutathione transferase activity
BK002_RS01545	COG2252	PERMEase
BK002_RS01550	COG0025	NhaP-type Na H and K H
BK002_RS01555	COG0583	DNA-binding transcription factor activity
BK002_RS01560	COG1380	Effector of murein hydrolase LrgA
BK002_RS01565	COG1346	cytolysis
BK002_RS01570	COG3539	Fimbrial protein
BK002_RS01600	COG3162	membrane
BK002_RS01605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BK002_RS01615	COG1301	dicarboxylic acid transport
BK002_RS01620	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BK002_RS01660	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS01665	COG1129	ABC transporter
BK002_RS01670	COG4191	Histidine kinase
BK002_RS01670	COG0784	Response regulator, receiver
BK002_RS01680	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BK002_RS01690	COG3454	Phosphonate metabolism
BK002_RS01695	COG4778	phosphonate C-P lyase system protein PhnL
BK002_RS01700	COG4107	phosphonate C-P lyase system protein PhnK
BK002_RS01705	COG3627	carbon phosphorus lyase activity
BK002_RS01710	COG3626	phosphonate metabolism
BK002_RS01715	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BK002_RS01720	COG3624	Phosphonate C-P lyase system protein PhnG
BK002_RS01725	COG2188	Transcriptional regulator
BK002_RS01730	COG2764	glyoxalase bleomycin resistance protein dioxygenase
BK002_RS01735	COG2824	Alkylphosphonate utilization operon protein PhnA
BK002_RS01745	COG2169	Transcriptional regulator
BK002_RS01750	COG1486	melibiose metabolic process
BK002_RS01790	COG0861	Integral membrane protein TerC family
BK002_RS01805	COG1215	transferase activity, transferring glycosyl groups
BK002_RS01810	COG1649	PFAM Uncharacterised BCR, COG1649
BK002_RS01810	COG0726	polysaccharide deacetylase
BK002_RS01815	COG0457	Tetratricopeptide repeat
BK002_RS01845	COG1309	transcriptional regulator
BK002_RS01860	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BK002_RS01865	COG1027	Aspartate ammonia-lyase
BK002_RS01870	COG3030	protein affecting phage T7 exclusion by the F plasmid
BK002_RS01875	COG0531	amino acid
BK002_RS01940	COG1509	lysine 2,3-aminomutase activity
BK002_RS01955	COG5510	response to toxic substance
BK002_RS01960	COG2076	Multidrug Resistance protein
BK002_RS01980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BK002_RS01985	COG1053	succinate dehydrogenase
BK002_RS02000	COG3264	Mechanosensitive ion channel
BK002_RS02000	COG1511	domain protein
BK002_RS02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK002_RS02040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BK002_RS02045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BK002_RS02045	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BK002_RS02050	COG0802	atpase or kinase
BK002_RS02055	COG0860	N-Acetylmuramoyl-L-alanine amidase
BK002_RS02075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BK002_RS02080	COG0330	HflC and HflK could
BK002_RS02085	COG0330	HflC and HflK could
BK002_RS02095	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BK002_RS02110	COG0557	exoribonuclease II activity
BK002_RS02115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BK002_RS02120	COG1960	acyl-CoA dehydrogenase activity
BK002_RS02130	COG3650	response to hydrogen peroxide
BK002_RS02135	COG1073	alpha beta
BK002_RS02195	COG2965	DNA replication, synthesis of RNA primer
BK002_RS02200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BK002_RS02210	COG3061	Opacity-associated protein A
BK002_RS02215	COG0545	Peptidyl-prolyl cis-trans isomerase
BK002_RS02220	COG1113	amino acid transport
BK002_RS02230	COG0697	spore germination
BK002_RS02240	COG0702	epimerase
BK002_RS02245	COG1733	regulation of RNA biosynthetic process
BK002_RS02260	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BK002_RS02295	COG1253	flavin adenine dinucleotide binding
BK002_RS02305	COG0729	surface antigen
BK002_RS02310	COG2911	Protein conserved in bacteria
BK002_RS02315	COG2105	PFAM AIG2 family protein
BK002_RS02330	COG1879	ABC-type sugar transport system periplasmic component
BK002_RS02335	COG1129	ABC transporter
BK002_RS02340	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS02345	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS02355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BK002_RS02380	COG0312	modulator of DNA gyrase
BK002_RS02415	COG3964	amidohydrolase
BK002_RS02430	COG2706	6-phosphogluconolactonase activity
BK002_RS02435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS02435	COG3711	transcriptional antiterminator
BK002_RS02440	COG3077	Addiction module antitoxin, RelB DinJ family
BK002_RS02445	COG2026	Addiction module toxin, RelE StbE family
BK002_RS02450	COG0602	queuosine metabolic process
BK002_RS02475	COG1486	melibiose metabolic process
BK002_RS02480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS02485	COG0366	Alpha amylase catalytic
BK002_RS02490	COG1263	PTS System
BK002_RS02490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BK002_RS02525	COG2731	YhcH YjgK YiaL family protein
BK002_RS02550	COG0525	valine-tRNA ligase activity
BK002_RS02555	COG2927	DNA polymerase III (CHI subunit)
BK002_RS02565	COG0795	lipopolysaccharide-transporting ATPase activity
BK002_RS02570	COG0795	lipopolysaccharide-transporting ATPase activity
BK002_RS02575	COG0433	COG0433 Predicted ATPase
BK002_RS02590	COG3718	enzyme involved in inositol metabolism
BK002_RS02595	COG1737	Transcriptional regulator
BK002_RS02595	COG0837	glucose binding
BK002_RS02600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BK002_RS02605	COG3962	Belongs to the TPP enzyme family
BK002_RS02615	COG1082	Xylose isomerase domain protein TIM barrel
BK002_RS02630	COG3842	ATPase activity
BK002_RS02635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BK002_RS02640	COG0395	ABC-type sugar transport system, permease component
BK002_RS02645	COG1175	transmembrane transport
BK002_RS02650	COG1064	alcohol dehydrogenase
BK002_RS02655	COG0659	secondary active sulfate transmembrane transporter activity
BK002_RS02660	COG0288	reversible hydration of carbon dioxide
BK002_RS02670	COG0582	viral genome integration into host DNA
BK002_RS02675	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BK002_RS02695	COG1196	nuclear chromosome segregation
BK002_RS02700	COG1715	Restriction endonuclease
BK002_RS02750	COG1216	Glycosyl transferase, family 2
BK002_RS02770	COG3507	Belongs to the glycosyl hydrolase 43 family
BK002_RS02775	COG2211	Major facilitator Superfamily
BK002_RS02780	COG2115	Belongs to the xylose isomerase family
BK002_RS02785	COG4580	involved in the transport of maltose and maltodextrins
BK002_RS02790	COG3272	Protein of unknown function (DUF1722)
BK002_RS02810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BK002_RS02825	COG0300	oxidoreductase activity
BK002_RS02830	COG3631	Ketosteroid isomerase-related protein
BK002_RS02835	COG0789	Transcriptional regulator
BK002_RS02840	COG3040	lipid binding
BK002_RS02850	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK002_RS02855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK002_RS02860	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK002_RS02865	COG1538	Outer membrane efflux protein
BK002_RS02870	COG0745	RESPONSE REGULATOR receiver
BK002_RS02875	COG5002	protein histidine kinase activity
BK002_RS02890	COG2850	peptidyl-arginine hydroxylation
BK002_RS02920	COG0842	Transport permease protein
BK002_RS02925	COG0842	Transport permease protein
BK002_RS02925	COG1129	ABC transporter
BK002_RS02930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK002_RS02935	COG3706	GGDEF domain
BK002_RS02945	COG1879	ABC-type sugar transport system periplasmic component
BK002_RS02950	COG1129	ABC transporter
BK002_RS02955	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS02965	COG2249	NAD(P)H dehydrogenase (quinone) activity
BK002_RS02970	COG0583	DNA-binding transcription factor activity
BK002_RS02980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK002_RS02985	COG5457	Domain of unknown function (DUF1127)
BK002_RS02995	COG1566	PFAM secretion protein HlyD family protein
BK002_RS03010	COG1924	4 iron, 4 sulfur cluster binding
BK002_RS03015	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BK002_RS03030	COG2733	membrane
BK002_RS03040	COG1917	Cupin 2, conserved barrel domain protein
BK002_RS03040	COG2207	Transcriptional regulator
BK002_RS03045	COG5464	transposase or invertase
BK002_RS03050	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS03060	COG0523	cobalamin synthesis protein
BK002_RS03065	COG2879	small protein
BK002_RS03070	COG1966	Carbon starvation protein
BK002_RS03075	COG2831	hemolysin activation secretion protein
BK002_RS03080	COG3210	domain, Protein
BK002_RS03095	COG3210	domain, Protein
BK002_RS03105	COG3210	domain, Protein
BK002_RS03110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BK002_RS03115	COG2368	4-hydroxyphenylacetate
BK002_RS03135	COG3971	2-oxopent-4-enoate hydratase activity
BK002_RS03145	COG3384	dioxygenase
BK002_RS03150	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS03160	COG0179	Fumarylacetoacetate (FAA) hydrolase
BK002_RS03170	COG1846	Transcriptional regulator
BK002_RS03195	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BK002_RS03210	COG3734	2-keto-3-deoxy-galactonokinase
BK002_RS03215	COG0800	Aldolase
BK002_RS03220	COG1737	Transcriptional regulator
BK002_RS03230	COG1214	PFAM Peptidase M22, glycoprotease
BK002_RS03230	COG0456	acetyltransferase
BK002_RS03235	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BK002_RS03235	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BK002_RS03250	COG3715	PTS system
BK002_RS03255	COG3716	PTS system mannose fructose sorbose family IID component
BK002_RS03260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BK002_RS03270	COG5464	transposase or invertase
BK002_RS03285	COG1484	DNA-dependent DNA replication
BK002_RS03300	COG2966	Psort location CytoplasmicMembrane, score
BK002_RS03315	COG2197	response regulator
BK002_RS03320	COG2197	response regulator
BK002_RS03325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BK002_RS03330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS03330	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS03335	COG4114	ferric iron reductase
BK002_RS03340	COG3706	GGDEF domain
BK002_RS03375	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BK002_RS03380	COG0456	acetyltransferase
BK002_RS03385	COG1011	Hydrolase
BK002_RS03395	COG2823	Periplasmic or secreted lipoprotein
BK002_RS03405	COG4667	esterase of the alpha-beta hydrolase superfamily
BK002_RS03410	COG0084	hydrolase, TatD family'
BK002_RS03415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BK002_RS03445	COG3726	membrane protein affecting hemolysin expression
BK002_RS03450	COG0560	Phosphoserine phosphatase
BK002_RS03455	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BK002_RS03465	COG0488	(ABC) transporter
BK002_RS03470	COG0741	lytic transglycosylase activity
BK002_RS03490	COG2207	Transcriptional regulator
BK002_RS03490	COG3708	Transcriptional regulator
BK002_RS03495	COG3045	CreA protein
BK002_RS03500	COG0745	RESPONSE REGULATOR receiver
BK002_RS03505	COG2205	protein histidine kinase activity
BK002_RS03510	COG4452	Inner membrane protein CreD
BK002_RS03515	COG0745	RESPONSE REGULATOR receiver
BK002_RS03525	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BK002_RS03535	COG0527	aspartate kinase activity
BK002_RS03535	COG0460	homoserine dehydrogenase
BK002_RS03545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BK002_RS03560	COG1115	amino acid carrier protein
BK002_RS03565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BK002_RS03570	COG0521	Mo-molybdopterin cofactor biosynthetic process
BK002_RS03575	COG0477	Major facilitator Superfamily
BK002_RS03580	COG1584	GPR1 FUN34 yaaH family protein
BK002_RS03585	COG4735	regulation of single-species biofilm formation
BK002_RS03610	COG0583	DNA-binding transcription factor activity
BK002_RS03620	COG0196	riboflavin kinase activity
BK002_RS03635	COG1047	Peptidyl-prolyl cis-trans
BK002_RS03660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BK002_RS03670	COG0505	Belongs to the CarA family
BK002_RS03715	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BK002_RS03725	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BK002_RS03730	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BK002_RS03745	COG3493	citrate carrier protein
BK002_RS03755	COG0564	pseudouridine synthase activity
BK002_RS03765	COG0417	DNA replication proofreading
BK002_RS03770	COG0235	Class ii aldolase
BK002_RS03790	COG0586	Pfam SNARE associated Golgi protein
BK002_RS03800	COG1178	ABC-type Fe3 transport system permease component
BK002_RS03820	COG2814	Major facilitator Superfamily
BK002_RS03825	COG2271	Major facilitator Superfamily
BK002_RS03830	COG0583	DNA-binding transcription factor activity
BK002_RS03840	COG0738	Major facilitator superfamily
BK002_RS03885	COG0028	Belongs to the TPP enzyme family
BK002_RS03895	COG1609	Transcriptional regulator
BK002_RS03915	COG0768	penicillin binding
BK002_RS03920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BK002_RS03925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BK002_RS03940	COG0772	Belongs to the SEDS family
BK002_RS03965	COG0849	cell division
BK002_RS03970	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BK002_RS03990	COG0494	nUDIX hydrolase
BK002_RS04015	COG1459	type II secretion system
BK002_RS04020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BK002_RS04025	COG4969	Belongs to the N-Me-Phe pilin family
BK002_RS04035	COG3023	N-Acetylmuramoyl-L-alanine amidase
BK002_RS04040	COG3725	Membrane protein required for beta-lactamase induction
BK002_RS04045	COG3940	Belongs to the glycosyl hydrolase 43 family
BK002_RS04050	COG2211	Major facilitator Superfamily
BK002_RS04055	COG1113	amino acid transport
BK002_RS04060	COG2186	Transcriptional regulator
BK002_RS04065	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BK002_RS04070	COG0508	dehydrogenase complex catalyzes the overall conversion of
BK002_RS04075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BK002_RS04090	COG3064	Membrane
BK002_RS04135	COG2132	Multicopper oxidase
BK002_RS04140	COG4993	Dehydrogenase
BK002_RS04155	COG0288	reversible hydration of carbon dioxide
BK002_RS04160	COG1131	(ABC) transporter
BK002_RS04165	COG0842	Transport permease protein
BK002_RS04170	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS04175	COG0726	polysaccharide deacetylase
BK002_RS04195	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BK002_RS04200	COG0617	tRNA 3'-terminal CCA addition
BK002_RS04220	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BK002_RS04225	COG1643	Atp-dependent helicase
BK002_RS04315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BK002_RS04320	COG4774	siderophore transport
BK002_RS04325	COG1120	ATPase activity
BK002_RS04330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BK002_RS04335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK002_RS04355	COG2860	membrane
BK002_RS04375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BK002_RS04380	COG3835	regulator
BK002_RS04395	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BK002_RS04400	COG0024	Methionine aminopeptidase
BK002_RS04425	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BK002_RS04435	COG0575	Belongs to the CDS family
BK002_RS04440	COG0750	zinc metalloprotease
BK002_RS04450	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BK002_RS04480	COG0587	DNA-directed DNA polymerase activity
BK002_RS04490	COG1982	Orn Lys Arg decarboxylase major
BK002_RS04495	COG0346	lactoylglutathione lyase activity
BK002_RS04505	COG4568	rho-dependent transcription termination
BK002_RS04520	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BK002_RS04525	COG3015	lipoprotein NlpE involved in copper resistance
BK002_RS04530	COG0791	NLP P60 protein
BK002_RS04540	COG1720	tRNA m6t6A37 methyltransferase activity
BK002_RS04550	COG1464	Belongs to the NlpA lipoprotein family
BK002_RS04555	COG2011	ABC-type metal ion transport system permease component
BK002_RS04565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BK002_RS04600	COG0656	L-ascorbic acid biosynthetic process
BK002_RS04605	COG0583	DNA-binding transcription factor activity
BK002_RS04610	COG2814	Major facilitator Superfamily
BK002_RS04620	COG2226	methyltransferase
BK002_RS04625	COG1388	LysM domain
BK002_RS04625	COG0741	lytic transglycosylase activity
BK002_RS04635	COG2226	methyltransferase
BK002_RS04645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BK002_RS04655	COG0583	DNA-binding transcription factor activity
BK002_RS04665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BK002_RS04670	COG1960	acyl-CoA dehydrogenase activity
BK002_RS04680	COG0121	glutamine amidotransferase
BK002_RS04685	COG3034	peptidoglycan biosynthetic process
BK002_RS04700	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BK002_RS04705	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BK002_RS04720	COG2991	Protein conserved in bacteria
BK002_RS04735	COG0454	-acetyltransferase
BK002_RS04740	COG2195	Cleaves the N-terminal amino acid of tripeptides
BK002_RS04760	COG1802	Transcriptional regulator
BK002_RS04765	COG1113	amino acid transport
BK002_RS04770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BK002_RS04775	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS04780	COG0579	oxidoreductase
BK002_RS04795	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BK002_RS04800	COG0625	glutathione transferase activity
BK002_RS04805	COG3775	system Galactitol-specific IIC component
BK002_RS04810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BK002_RS04815	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS04820	COG1070	Carbohydrate kinase
BK002_RS04840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BK002_RS04845	COG0508	dehydrogenase complex catalyzes the overall conversion of
BK002_RS04850	COG0022	dehydrogenase e1 component
BK002_RS04855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BK002_RS04860	COG2909	trisaccharide binding
BK002_RS04885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BK002_RS04895	COG0582	viral genome integration into host DNA
BK002_RS05055	COG0791	NLP P60 protein
BK002_RS05070	COG3639	organic phosphonate transmembrane transporter activity
BK002_RS05080	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BK002_RS05105	COG3188	usher protein
BK002_RS05120	COG0765	amino acid transport
BK002_RS05125	COG4597	amino acid ABC transporter
BK002_RS05130	COG1126	abc transporter atp-binding protein
BK002_RS05135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK002_RS05175	COG4302	ethanolamine ammonia-lyase activity
BK002_RS05180	COG4303	Ethanolamine ammonia lyase large subunit
BK002_RS05195	COG0833	amino acid
BK002_RS05200	COG2040	homocysteine
BK002_RS05205	COG4521	taurine ABC transporter
BK002_RS05210	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BK002_RS05215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BK002_RS05220	COG2175	clavaminate synthase activity
BK002_RS05230	COG1943	Transposase
BK002_RS05235	COG0113	porphobilinogen synthase activity
BK002_RS05240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BK002_RS05245	COG1335	isochorismatase
BK002_RS05250	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BK002_RS05290	COG1785	Belongs to the alkaline phosphatase family
BK002_RS05300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BK002_RS05310	COG3416	Protein conserved in bacteria
BK002_RS05315	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BK002_RS05325	COG4126	flavin adenine dinucleotide binding
BK002_RS05340	COG1940	carbohydrate kinase activity
BK002_RS05345	COG0419	ATPase involved in DNA repair
BK002_RS05350	COG0420	3'-5' exonuclease activity
BK002_RS05375	COG0366	Alpha amylase catalytic
BK002_RS05380	COG0583	DNA-binding transcription factor activity
BK002_RS05385	COG1335	isochorismatase
BK002_RS05395	COG1228	amidohydrolase
BK002_RS05405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BK002_RS05420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS05430	COG0450	alkyl hydroperoxide reductase
BK002_RS05455	COG1862	Preprotein translocase
BK002_RS05460	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BK002_RS05465	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BK002_RS05485	COG4238	major outer membrane lipoprotein
BK002_RS05495	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BK002_RS05495	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BK002_RS05515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BK002_RS05520	COG0667	Aldo Keto reductase
BK002_RS05530	COG0142	geranyltranstransferase activity
BK002_RS05550	COG0693	protein deglycase activity
BK002_RS05555	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BK002_RS05565	COG2814	Major facilitator Superfamily
BK002_RS05570	COG0673	inositol 2-dehydrogenase activity
BK002_RS05585	COG1053	succinate dehydrogenase
BK002_RS05595	COG1053	succinate dehydrogenase
BK002_RS05600	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BK002_RS05605	COG1414	Transcriptional regulator
BK002_RS05620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BK002_RS05625	COG1845	cytochrome c oxidase, subunit III
BK002_RS05630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BK002_RS05635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BK002_RS05640	COG2223	nitrite transmembrane transporter activity
BK002_RS05645	COG3056	Lipoprotein
BK002_RS05650	COG0271	Belongs to the BolA IbaG family
BK002_RS05670	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BK002_RS05675	COG0776	regulation of translation
BK002_RS05680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BK002_RS05685	COG1555	photosystem II stabilization
BK002_RS05690	COG0824	Thioesterase
BK002_RS05700	COG4533	DNA binding
BK002_RS05715	COG1522	sequence-specific DNA binding
BK002_RS05720	COG1132	(ABC) transporter
BK002_RS05725	COG1132	(ABC) transporter
BK002_RS05730	COG0347	Belongs to the P(II) protein family
BK002_RS05735	COG0004	ammonium transporteR
BK002_RS05740	COG1946	Acyl-CoA thioesterase
BK002_RS05745	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BK002_RS05750	COG3695	enzyme binding
BK002_RS05780	COG2364	Membrane
BK002_RS05805	COG2182	Extracellular solute-binding protein
BK002_RS05810	COG1175	transmembrane transport
BK002_RS05815	COG3833	ABC-type maltose transport systems, permease component
BK002_RS05820	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BK002_RS05825	COG1874	Beta-galactosidase
BK002_RS05875	COG0110	maltose O-acetyltransferase activity
BK002_RS05890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK002_RS05895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK002_RS05900	COG1309	transcriptional regulator
BK002_RS05905	COG1196	nuclear chromosome segregation
BK002_RS05905	COG3264	Mechanosensitive ion channel
BK002_RS05920	COG3923	Primosomal replication protein n
BK002_RS05925	COG2832	Protein of unknown function (DUF454)
BK002_RS05965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BK002_RS05970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BK002_RS05970	COG4651	solute:proton antiporter activity
BK002_RS05975	COG2223	nitrite transmembrane transporter activity
BK002_RS05985	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BK002_RS05990	COG3735	TraB family
BK002_RS06005	COG1585	Membrane protein implicated in regulation of membrane protease activity
BK002_RS06010	COG0330	HflC and HflK could
BK002_RS06025	COG0390	transport system, permease component
BK002_RS06030	COG3118	belongs to the thioredoxin family
BK002_RS06035	COG0300	oxidoreductase activity
BK002_RS06040	COG2755	lipolytic protein G-D-S-L family
BK002_RS06045	COG4181	ATPase activity
BK002_RS06050	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BK002_RS06070	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BK002_RS06075	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BK002_RS06090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BK002_RS06100	COG2501	S4 domain
BK002_RS06155	COG1560	Kdo2-lipid A biosynthetic process
BK002_RS06165	COG3710	Transcriptional regulator
BK002_RS06170	COG0531	amino acid
BK002_RS06175	COG1982	Orn Lys Arg decarboxylase major
BK002_RS06180	COG3104	oligopeptide transport
BK002_RS06200	COG0673	inositol 2-dehydrogenase activity
BK002_RS06210	COG0673	inositol 2-dehydrogenase activity
BK002_RS06225	COG1129	ABC transporter
BK002_RS06230	COG4211	Belongs to the binding-protein-dependent transport system permease family
BK002_RS06275	COG1566	PFAM secretion protein HlyD family protein
BK002_RS06280	COG1120	ATPase activity
BK002_RS06285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK002_RS06305	COG1473	amidohydrolase
BK002_RS06310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK002_RS06315	COG0667	Aldo Keto reductase
BK002_RS06365	COG4680	protein conserved in bacteria
BK002_RS06380	COG0531	amino acid
BK002_RS06390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BK002_RS06395	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS06410	COG1113	amino acid transport
BK002_RS06415	COG2211	Major facilitator Superfamily
BK002_RS06425	COG0673	inositol 2-dehydrogenase activity
BK002_RS06435	COG1609	Transcriptional regulator
BK002_RS06440	COG0668	transmembrane transport
BK002_RS06445	COG0477	Major facilitator Superfamily
BK002_RS06470	COG0778	Nitroreductase
BK002_RS06475	COG2315	Protein conserved in bacteria
BK002_RS06515	COG3698	Phosphodiester glycosidase
BK002_RS06525	COG0697	spore germination
BK002_RS06540	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BK002_RS06550	COG4215	(ABC) transporter
BK002_RS06560	COG4221	oxidoreductase activity
BK002_RS06565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BK002_RS06570	COG4608	Belongs to the ABC transporter superfamily
BK002_RS06575	COG0444	Belongs to the ABC transporter superfamily
BK002_RS06580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BK002_RS06585	COG0601	transmembrane transport
BK002_RS06590	COG0747	negative chemotaxis
BK002_RS06615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BK002_RS06625	COG0668	transmembrane transport
BK002_RS06630	COG0583	DNA-binding transcription factor activity
BK002_RS06640	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS06650	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS06655	COG1129	ABC transporter
BK002_RS06675	COG1879	ABC-type sugar transport system periplasmic component
BK002_RS06680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BK002_RS06685	COG2390	Transcriptional regulator
BK002_RS06690	COG3959	Transketolase, thiamine diphosphate binding domain
BK002_RS06695	COG3958	Transketolase
BK002_RS06700	COG2977	Belongs to the P-Pant transferase superfamily
BK002_RS06705	COG4771	TonB-dependent receptor
BK002_RS06710	COG2382	esterase
BK002_RS06715	COG3251	PFAM MbtH domain protein
BK002_RS06720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BK002_RS06720	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BK002_RS06725	COG1120	ATPase activity
BK002_RS06730	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK002_RS06735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK002_RS06765	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BK002_RS06775	COG1169	isochorismate synthase
BK002_RS06780	COG1021	2,3-dihydroxybenzoate-AMP ligase
BK002_RS06785	COG3433	isochorismatase activity
BK002_RS06785	COG1535	isochorismatase
BK002_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS06800	COG1966	Carbon starvation protein
BK002_RS06805	COG2879	small protein
BK002_RS06820	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS06825	COG0371	Dehydrogenase
BK002_RS06830	COG1129	ABC transporter
BK002_RS06835	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS06865	COG2271	Major facilitator Superfamily
BK002_RS06870	COG0483	inositol monophosphate 1-phosphatase activity
BK002_RS06880	COG0402	S-adenosylhomocysteine deaminase activity
BK002_RS06890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BK002_RS06905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BK002_RS06915	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS06920	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS06925	COG1129	ABC transporter
BK002_RS06950	COG0436	Aminotransferase
BK002_RS06955	COG1475	DNA binding
BK002_RS06960	COG3969	phosphoadenosine phosphosulfate
BK002_RS06965	COG0583	DNA-binding transcription factor activity
BK002_RS06970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BK002_RS06990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BK002_RS06995	COG3719	Belongs to the RNase T2 family
BK002_RS07000	COG3069	C4-dicarboxylate transmembrane transporter activity
BK002_RS07020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BK002_RS07025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BK002_RS07035	COG0583	DNA-binding transcription factor activity
BK002_RS07050	COG1686	Belongs to the peptidase S11 family
BK002_RS07055	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BK002_RS07060	COG0772	Belongs to the SEDS family
BK002_RS07065	COG0768	penicillin binding
BK002_RS07075	COG0799	negative regulation of ribosome biogenesis
BK002_RS07090	COG1466	dna polymerase III delta subunit
BK002_RS07105	COG2888	peptidyl-tyrosine sulfation
BK002_RS07120	COG1126	abc transporter atp-binding protein
BK002_RS07125	COG0765	amino acid transport
BK002_RS07130	COG0765	amino acid transport
BK002_RS07155	COG1702	phosphate starvation-inducible protein PhoH
BK002_RS07165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BK002_RS07205	COG0367	asparagine synthase
BK002_RS07210	COG0647	UMP catabolic process
BK002_RS07215	COG1846	Transcriptional regulator
BK002_RS07215	COG1940	carbohydrate kinase activity
BK002_RS07220	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BK002_RS07260	COG0735	belongs to the Fur family
BK002_RS07275	COG0596	Alpha beta hydrolase
BK002_RS07285	COG0033	Phosphoglucomutase
BK002_RS07295	COG0745	RESPONSE REGULATOR receiver
BK002_RS07300	COG2205	protein histidine kinase activity
BK002_RS07330	COG0415	Belongs to the DNA photolyase family
BK002_RS07345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BK002_RS07350	COG1984	allophanate hydrolase subunit 2
BK002_RS07385	COG2009	succinate dehydrogenase
BK002_RS07390	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BK002_RS07395	COG1053	succinate dehydrogenase
BK002_RS07400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BK002_RS07405	COG0567	Dehydrogenase, E1 component
BK002_RS07410	COG0508	dehydrogenase complex catalyzes the overall conversion of
BK002_RS07420	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BK002_RS07425	COG1271	oxidase subunit
BK002_RS07430	COG1294	oxidase, subunit
BK002_RS07435	COG4890	Cyd operon protein YbgT
BK002_RS07440	COG3790	cyd operon protein YbgE
BK002_RS07445	COG0824	Thioesterase
BK002_RS07450	COG0811	peptide transport
BK002_RS07455	COG0848	biopolymer transport protein
BK002_RS07460	COG3064	Membrane
BK002_RS07470	COG2885	chlorophyll binding
BK002_RS07475	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BK002_RS07520	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BK002_RS07525	COG3201	nicotinamide mononucleotide transporter
BK002_RS07540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BK002_RS07550	COG2017	converts alpha-aldose to the beta-anomer
BK002_RS07560	COG1085	galactose-1-phosphate uridylyltransferase
BK002_RS07570	COG1119	ATPase activity
BK002_RS07575	COG2005	Transcriptional regulator
BK002_RS07575	COG3585	molybdate ion transport
BK002_RS07585	COG0725	ABC transporter, periplasmic molybdate-binding protein
BK002_RS07590	COG4149	molybdate abc transporter
BK002_RS07600	COG0561	phosphatase activity
BK002_RS07625	COG2200	EAL domain
BK002_RS07630	COG0789	Transcriptional regulator
BK002_RS07665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK002_RS07670	COG0589	response to stress
BK002_RS07680	COG4677	pectinesterase activity
BK002_RS07720	COG1881	PFAM PEBP family protein
BK002_RS07725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BK002_RS07740	COG2226	methyltransferase
BK002_RS07765	COG0642	Histidine kinase
BK002_RS07770	COG0745	RESPONSE REGULATOR receiver
BK002_RS07790	COG0521	Mo-molybdopterin cofactor biosynthetic process
BK002_RS07800	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BK002_RS07805	COG0314	molybdopterin synthase activity
BK002_RS07810	COG0670	Belongs to the BI1 family
BK002_RS07815	COG0392	lysyltransferase activity
BK002_RS07820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BK002_RS07825	COG3568	Endonuclease Exonuclease Phosphatase
BK002_RS07835	COG0842	Transport permease protein
BK002_RS07840	COG0842	Transport permease protein
BK002_RS07845	COG1131	(ABC) transporter
BK002_RS07850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK002_RS07855	COG1309	transcriptional regulator
BK002_RS07860	COG0583	DNA-binding transcription factor activity
BK002_RS07870	COG2271	Major facilitator Superfamily
BK002_RS07875	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS07880	COG3959	Transketolase, thiamine diphosphate binding domain
BK002_RS07885	COG3958	Transketolase
BK002_RS07890	COG0513	Belongs to the DEAD box helicase family
BK002_RS07895	COG1199	ATP-dependent helicase activity
BK002_RS07900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BK002_RS07910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BK002_RS07920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BK002_RS07930	COG0668	transmembrane transport
BK002_RS07935	COG1126	abc transporter atp-binding protein
BK002_RS07940	COG0765	amino acid transport
BK002_RS07945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK002_RS07960	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BK002_RS07965	COG2194	sulfuric ester hydrolase activity
BK002_RS07980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BK002_RS07985	COG2723	6-phospho-beta-galactosidase activity
BK002_RS07990	COG2188	Transcriptional regulator
BK002_RS07995	COG1376	ErfK ybiS ycfS ynhG family protein
BK002_RS08000	COG2365	Tyrosine phosphatase family
BK002_RS08005	COG0488	(ABC) transporter
BK002_RS08015	COG2271	Major facilitator Superfamily
BK002_RS08020	COG1609	Transcriptional regulator
BK002_RS08030	COG0561	phosphatase activity
BK002_RS08035	COG1882	Formate acetyltransferase
BK002_RS08040	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BK002_RS08045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BK002_RS08050	COG0303	'Molybdopterin
BK002_RS08065	COG0747	negative chemotaxis
BK002_RS08085	COG2223	nitrite transmembrane transporter activity
BK002_RS08095	COG2133	pyrroloquinoline quinone binding
BK002_RS08100	COG0625	glutathione transferase activity
BK002_RS08110	COG1686	Belongs to the peptidase S11 family
BK002_RS08115	COG1349	DNA-binding transcription factor activity
BK002_RS08120	COG0671	phosphoesterase, PA-phosphatase related
BK002_RS08125	COG2814	Major facilitator Superfamily
BK002_RS08130	COG0561	phosphatase activity
BK002_RS08135	COG0738	Major facilitator superfamily
BK002_RS08140	COG3226	Transcriptional regulator
BK002_RS08165	COG0778	Nitroreductase
BK002_RS08180	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BK002_RS08185	COG3842	ATPase activity
BK002_RS08190	COG1176	ABC-type spermidine putrescine transport system, permease component I
BK002_RS08195	COG1177	transmembrane transport
BK002_RS08210	COG0745	RESPONSE REGULATOR receiver
BK002_RS08215	COG5002	protein histidine kinase activity
BK002_RS08220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK002_RS08225	COG4160	amino acid transport
BK002_RS08230	COG4215	(ABC) transporter
BK002_RS08235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK002_RS08240	COG1126	abc transporter atp-binding protein
BK002_RS08250	COG3706	GGDEF domain
BK002_RS08250	COG2203	Gaf domain
BK002_RS08250	COG4251	negative regulation of phosphorylation
BK002_RS08250	COG5001	Diguanylate cyclase
BK002_RS08255	COG3023	N-Acetylmuramoyl-L-alanine amidase
BK002_RS08260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BK002_RS08265	COG0702	epimerase
BK002_RS08270	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BK002_RS08275	COG0028	Belongs to the TPP enzyme family
BK002_RS08285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BK002_RS08295	COG2431	L-lysine efflux transmembrane transporter activity
BK002_RS08305	COG3593	DNA synthesis involved in DNA repair
BK002_RS08310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK002_RS08320	COG1278	Cold shock
BK002_RS08330	COG0542	response to heat
BK002_RS08345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BK002_RS08350	COG4988	ABC transporter
BK002_RS08355	COG0492	ferredoxin-NADP+ reductase activity
BK002_RS08365	COG1178	ABC-type Fe3 transport system permease component
BK002_RS08365	COG1674	ftsk spoiiie
BK002_RS08375	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BK002_RS08385	COG0243	molybdopterin cofactor binding
BK002_RS08390	COG0437	4 iron, 4 sulfur cluster binding
BK002_RS08395	COG3302	dmso reductase anchor subunit
BK002_RS08400	COG0477	Major facilitator Superfamily
BK002_RS08405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BK002_RS08410	COG1882	Formate acetyltransferase
BK002_RS08415	COG2116	formate transmembrane transporter activity
BK002_RS08420	COG1944	ATP diphosphatase activity
BK002_RS08425	COG2323	membrane
BK002_RS08445	COG0539	negative regulation of cytoplasmic translation
BK002_RS08455	COG0658	competence protein
BK002_RS08455	COG2333	competence protein COMEC
BK002_RS08470	COG3214	Protein conserved in bacteria
BK002_RS08485	COG3173	Aminoglycoside phosphotransferase
BK002_RS08490	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BK002_RS08495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BK002_RS08505	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BK002_RS08515	COG2989	Protein conserved in bacteria
BK002_RS08520	COG3108	Peptidase M15
BK002_RS08525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BK002_RS08530	COG1448	Aminotransferase
BK002_RS08535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BK002_RS08555	COG0814	amino acid
BK002_RS08565	COG1473	amidohydrolase
BK002_RS08575	COG0308	aminopeptidase N
BK002_RS08585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BK002_RS08590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BK002_RS08595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BK002_RS08600	COG0431	NADPH-dependent FMN reductase
BK002_RS08615	COG0633	Ferredoxin
BK002_RS08615	COG3217	Mosc domain protein beta barrel domain protein
BK002_RS08625	COG0488	(ABC) transporter
BK002_RS08630	COG2995	paraquat-inducible protein a
BK002_RS08635	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BK002_RS08635	COG3008	intermembrane lipid transfer
BK002_RS08640	COG3009	Protein conserved in bacteria
BK002_RS08645	COG3130	regulation of translation
BK002_RS08655	COG1067	ATP-dependent peptidase activity
BK002_RS08675	COG3070	regulator of competence-specific genes
BK002_RS08680	COG1289	transmembrane transporter activity
BK002_RS08685	COG3304	Inner membrane component domain
BK002_RS08690	COG0210	DNA helicase
BK002_RS08700	COG1832	CoA-binding protein
BK002_RS08715	COG1881	PFAM PEBP family protein
BK002_RS08720	COG2207	Transcriptional regulator
BK002_RS08735	COG0670	Belongs to the BI1 family
BK002_RS08750	COG0058	SHG alpha-glucan phosphorylase activity
BK002_RS08760	COG2200	EAL domain
BK002_RS08780	COG3706	GGDEF domain
BK002_RS08785	COG2207	Transcriptional regulator
BK002_RS08795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BK002_RS08800	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BK002_RS08805	COG1882	Formate acetyltransferase
BK002_RS08810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BK002_RS08815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BK002_RS08820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS08820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BK002_RS08820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS08825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BK002_RS08830	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS08835	COG4638	Rieske (2fe-2S)
BK002_RS08840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BK002_RS08845	COG0473	3-isopropylmalate dehydrogenase activity
BK002_RS08850	COG0583	DNA-binding transcription factor activity
BK002_RS08855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BK002_RS08860	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS08865	COG1396	sequence-specific DNA binding
BK002_RS08865	COG1917	Cupin 2, conserved barrel domain protein
BK002_RS08870	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BK002_RS08875	COG0174	glutamine synthetase
BK002_RS08880	COG0531	amino acid
BK002_RS08895	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS08925	COG3729	General stress protein
BK002_RS08935	COG2233	PERMEase
BK002_RS08970	COG1309	transcriptional regulator
BK002_RS08985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BK002_RS08995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BK002_RS09015	COG1702	phosphate starvation-inducible protein PhoH
BK002_RS09020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BK002_RS09030	COG1335	isochorismatase
BK002_RS09040	COG0583	DNA-binding transcription factor activity
BK002_RS09065	COG3381	protein complex oligomerization
BK002_RS09100	COG5645	(Lipo)protein
BK002_RS09115	COG1560	Kdo2-lipid A biosynthetic process
BK002_RS09160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BK002_RS09180	COG2814	Major facilitator Superfamily
BK002_RS09185	COG0583	DNA-binding transcription factor activity
BK002_RS09190	COG1530	ribonuclease E activity
BK002_RS09210	COG1399	metal-binding, possibly nucleic acid-binding protein
BK002_RS09230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BK002_RS09245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BK002_RS09250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BK002_RS09255	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BK002_RS09265	COG0470	DNA polymerase III
BK002_RS09270	COG0084	hydrolase, TatD family'
BK002_RS09290	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BK002_RS09300	COG0537	adenosine 5'-monophosphoramidase activity
BK002_RS09305	COG5633	Lipoprotein
BK002_RS09330	COG1252	NADH dehydrogenase
BK002_RS09335	COG3134	Outer membrane lipoprotein
BK002_RS09350	COG1309	transcriptional regulator
BK002_RS09365	COG1376	ErfK ybiS ycfS ynhG family protein
BK002_RS09365	COG1388	LysM domain
BK002_RS09370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BK002_RS09380	COG4591	ABC-type transport system involved in lipoprotein release permease component
BK002_RS09390	COG4591	ABC-type transport system involved in lipoprotein release permease component
BK002_RS09400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BK002_RS09410	COG2390	Transcriptional regulator
BK002_RS09425	COG3395	kinase activity
BK002_RS09440	COG0698	ribose 5-phosphate isomerase
BK002_RS09445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BK002_RS09450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BK002_RS09455	COG0318	PFAM AMP-dependent synthetase and ligase
BK002_RS09470	COG1177	transmembrane transport
BK002_RS09490	COG2850	peptidyl-arginine hydroxylation
BK002_RS09495	COG2205	protein histidine kinase activity
BK002_RS09515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BK002_RS09535	COG1187	pseudouridine synthase activity
BK002_RS09540	COG0538	isocitrate dehydrogenase activity
BK002_RS09545	COG0640	Transcriptional regulator
BK002_RS09565	COG3813	Protein conserved in bacteria
BK002_RS09570	COG1063	alcohol dehydrogenase
BK002_RS09580	COG3729	General stress protein
BK002_RS09585	COG3685	Protein conserved in bacteria
BK002_RS09590	COG3685	Protein conserved in bacteria
BK002_RS09595	COG3546	catalase activity
BK002_RS09600	COG1271	oxidase subunit
BK002_RS09605	COG1294	oxidase, subunit
BK002_RS09635	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BK002_RS09640	COG0583	DNA-binding transcription factor activity
BK002_RS09645	COG3706	GGDEF domain
BK002_RS09650	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BK002_RS09660	COG1560	Kdo2-lipid A biosynthetic process
BK002_RS09670	COG3182	Iron-regulated membrane protein
BK002_RS09690	COG2199	diguanylate cyclase activity
BK002_RS09690	COG2203	Gaf domain
BK002_RS09695	COG4974	Belongs to the 'phage' integrase family
BK002_RS09735	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BK002_RS09775	COG4695	Portal protein
BK002_RS09910	COG3042	response to heat
BK002_RS09915	COG3189	MarR family transcriptional regulator
BK002_RS09920	COG1683	Conserved Protein
BK002_RS09925	COG0504	CTP synthase activity
BK002_RS09930	COG2807	transmembrane transport
BK002_RS09935	COG2207	Transcriptional regulator
BK002_RS09945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BK002_RS09950	COG0859	PFAM glycosyl transferase family 9
BK002_RS09960	COG3344	reverse transcriptase
BK002_RS09965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BK002_RS09970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BK002_RS09975	COG0583	DNA-binding transcription factor activity
BK002_RS09980	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS10005	COG0386	Belongs to the glutathione peroxidase family
BK002_RS10020	COG2766	serine protein kinase
BK002_RS10025	COG3713	MltA-interacting MipA family protein
BK002_RS10030	COG0656	L-ascorbic acid biosynthetic process
BK002_RS10050	COG3139	Protein of unknown function (DUF1315)
BK002_RS10065	COG1335	isochorismatase
BK002_RS10070	COG0252	asparaginase activity
BK002_RS10075	COG0616	signal peptide processing
BK002_RS10080	COG0778	Nitroreductase
BK002_RS10090	COG0709	Synthesizes selenophosphate from selenide and ATP
BK002_RS10095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BK002_RS10100	COG3321	synthase
BK002_RS10100	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS10100	COG0604	alcohol dehydrogenase
BK002_RS10105	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BK002_RS10110	COG0494	nUDIX hydrolase
BK002_RS10115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BK002_RS10120	COG2897	thiosulfate sulfurtransferase activity
BK002_RS10125	COG4136	ATPase activity
BK002_RS10130	COG4135	transport system, permease component
BK002_RS10135	COG4134	Bacterial extracellular solute-binding protein
BK002_RS10140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BK002_RS10145	COG0398	Pfam SNARE associated Golgi protein
BK002_RS10150	COG0398	Pfam SNARE associated Golgi protein
BK002_RS10155	COG0708	Exodeoxyribonuclease III
BK002_RS10165	COG3138	arginine N-succinyltransferase
BK002_RS10175	COG3724	N-succinylarginine dihydrolase activity
BK002_RS10185	COG3678	ATP-independent chaperone mediated protein folding
BK002_RS10190	COG0322	excinuclease ABC activity
BK002_RS10200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BK002_RS10205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS10215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS10220	COG1447	Phosphotransferase system cellobiose-specific component IIA
BK002_RS10225	COG1917	Cupin 2, conserved barrel domain protein
BK002_RS10225	COG2169	Transcriptional regulator
BK002_RS10230	COG1486	melibiose metabolic process
BK002_RS10240	COG0753	catalase activity
BK002_RS10250	COG1823	symporter activity
BK002_RS10255	COG1988	membrane-bound metal-dependent
BK002_RS10260	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS10265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BK002_RS10295	COG0727	PFAM Uncharacterised protein family (UPF0153)
BK002_RS10300	COG3047	cAMP biosynthetic process
BK002_RS10310	COG4774	siderophore transport
BK002_RS10365	COG0135	phosphoribosylanthranilate isomerase activity
BK002_RS10365	COG0134	indole-3-glycerol-phosphate synthase activity
BK002_RS10370	COG0512	Glutamine amidotransferase of anthranilate synthase
BK002_RS10370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BK002_RS10375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BK002_RS10385	COG0009	L-threonylcarbamoyladenylate synthase
BK002_RS10395	COG0583	DNA-binding transcription factor activity
BK002_RS10420	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BK002_RS10425	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS10435	COG0616	signal peptide processing
BK002_RS10460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BK002_RS10470	COG0671	phosphoesterase, PA-phosphatase related
BK002_RS10475	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BK002_RS10480	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BK002_RS10490	COG0023	Translation Initiation Factor
BK002_RS10500	COG1349	DNA-binding transcription factor activity
BK002_RS10515	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BK002_RS10515	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BK002_RS10520	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BK002_RS10530	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BK002_RS10545	COG4171	peptide transport system, permease
BK002_RS10560	COG0702	epimerase
BK002_RS10575	COG1473	amidohydrolase
BK002_RS10585	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BK002_RS10590	COG1842	Phage shock protein A
BK002_RS10600	COG1983	PspC domain protein
BK002_RS10610	COG3106	COG3106 Predicted ATPase
BK002_RS10620	COG0583	DNA-binding transcription factor activity
BK002_RS10625	COG1486	melibiose metabolic process
BK002_RS10635	COG3180	Ammonia monooxygenase
BK002_RS10640	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BK002_RS10645	COG4948	Mandelate Racemase Muconate Lactonizing
BK002_RS10650	COG2866	Carboxypeptidase
BK002_RS10660	COG4166	transmembrane transport
BK002_RS10690	COG0656	L-ascorbic acid biosynthetic process
BK002_RS10695	COG3250	beta-galactosidase activity
BK002_RS10760	COG0583	DNA-binding transcription factor activity
BK002_RS10765	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS10770	COG1078	dGTPase activity
BK002_RS10775	COG0693	protein deglycase activity
BK002_RS10800	COG2885	chlorophyll binding
BK002_RS10920	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS10925	COG1309	transcriptional regulator
BK002_RS10930	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS10950	COG0583	DNA-binding transcription factor activity
BK002_RS10980	COG0604	alcohol dehydrogenase
BK002_RS10985	COG0436	Aminotransferase
BK002_RS11000	COG2011	ABC-type metal ion transport system permease component
BK002_RS11005	COG1448	Aminotransferase
BK002_RS11015	COG1522	sequence-specific DNA binding
BK002_RS11020	COG1113	amino acid transport
BK002_RS11035	COG0673	inositol 2-dehydrogenase activity
BK002_RS11040	COG1349	DNA-binding transcription factor activity
BK002_RS11050	COG0513	Belongs to the DEAD box helicase family
BK002_RS11060	COG0589	response to stress
BK002_RS11070	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BK002_RS11075	COG1013	pyruvate-flavodoxin oxidoreductase activity
BK002_RS11075	COG0674	pyruvate-flavodoxin oxidoreductase activity
BK002_RS11075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BK002_RS11075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BK002_RS11080	COG3042	response to heat
BK002_RS11085	COG3187	Heat shock protein
BK002_RS11090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BK002_RS11095	COG0586	Pfam SNARE associated Golgi protein
BK002_RS11100	COG2911	Protein conserved in bacteria
BK002_RS11110	COG3784	Protein of unknown function (DUF1318)
BK002_RS11115	COG2207	Transcriptional regulator
BK002_RS11120	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS11140	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS11140	COG2030	dehydratase
BK002_RS11145	COG3396	Phenylacetate-CoA oxygenase
BK002_RS11150	COG3460	Phenylacetate-CoA oxygenase
BK002_RS11155	COG3396	Phenylacetate-CoA oxygenase
BK002_RS11160	COG2151	metal-sulfur cluster biosynthetic enzyme
BK002_RS11165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BK002_RS11170	COG1024	Enoyl-CoA hydratase
BK002_RS11175	COG1024	Enoyl-CoA hydratase
BK002_RS11180	COG1250	3-hydroxyacyl-CoA dehydrogenase
BK002_RS11185	COG2050	protein possibly involved in aromatic compounds catabolism
BK002_RS11190	COG0183	Belongs to the thiolase family
BK002_RS11195	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BK002_RS11200	COG3327	negative regulation of DNA-templated transcription, initiation
BK002_RS11205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BK002_RS11220	COG1643	Atp-dependent helicase
BK002_RS11225	COG4122	O-methyltransferase activity
BK002_RS11250	COG0583	DNA-binding transcription factor activity
BK002_RS11255	COG0667	Aldo Keto reductase
BK002_RS11260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BK002_RS11270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BK002_RS11275	COG3138	arginine N-succinyltransferase
BK002_RS11280	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS11285	COG3724	N-succinylarginine dihydrolase activity
BK002_RS11290	COG2988	succinylglutamate desuccinylase activity
BK002_RS11295	COG1113	amino acid transport
BK002_RS11300	COG0477	Major facilitator Superfamily
BK002_RS11305	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BK002_RS11315	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS11320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BK002_RS11325	COG0401	homolog of Blt101
BK002_RS11330	COG5562	phage envelope protein
BK002_RS11335	COG0425	Belongs to the sulfur carrier protein TusA family
BK002_RS11365	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BK002_RS11370	COG1263	PTS System
BK002_RS11370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BK002_RS11375	COG1609	Transcriptional regulator
BK002_RS11380	COG5339	Protein conserved in bacteria
BK002_RS11385	COG1482	cell wall glycoprotein biosynthetic process
BK002_RS11390	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BK002_RS11390	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BK002_RS11395	COG0114	fumarate hydratase activity
BK002_RS11405	COG2205	protein histidine kinase activity
BK002_RS11415	COG0745	RESPONSE REGULATOR receiver
BK002_RS11420	COG3136	membrane protein required for alginate biosynthesis
BK002_RS11430	COG0531	amino acid
BK002_RS11445	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BK002_RS11450	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BK002_RS11465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BK002_RS11480	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BK002_RS11485	COG1473	amidohydrolase
BK002_RS11495	COG0583	DNA-binding transcription factor activity
BK002_RS11500	COG2840	Smr protein MutS2
BK002_RS11505	COG1414	Transcriptional regulator
BK002_RS11515	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BK002_RS11520	COG0183	Belongs to the thiolase family
BK002_RS11530	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BK002_RS11535	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BK002_RS11545	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BK002_RS11545	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BK002_RS11565	COG4565	transcriptional regulatory protein
BK002_RS11570	COG3290	protein histidine kinase activity
BK002_RS11595	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BK002_RS11605	COG0679	Auxin Efflux Carrier
BK002_RS11635	COG0628	permease
BK002_RS11655	COG3591	Belongs to the peptidase S1B family
BK002_RS11665	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BK002_RS11670	COG2814	Major facilitator Superfamily
BK002_RS11675	COG0583	DNA-binding transcription factor activity
BK002_RS11680	COG1940	carbohydrate kinase activity
BK002_RS11685	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BK002_RS11700	COG3302	dmso reductase anchor subunit
BK002_RS11705	COG0437	4 iron, 4 sulfur cluster binding
BK002_RS11710	COG0243	molybdopterin cofactor binding
BK002_RS11725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BK002_RS11740	COG2271	Major facilitator Superfamily
BK002_RS11745	COG0246	Mannitol dehydrogenase
BK002_RS11750	COG0589	response to stress
BK002_RS11755	COG1802	Transcriptional regulator
BK002_RS11760	COG4221	oxidoreductase activity
BK002_RS11775	COG2207	Transcriptional regulator
BK002_RS11780	COG2135	peptidase activity
BK002_RS11825	COG0071	Belongs to the small heat shock protein (HSP20) family
BK002_RS11830	COG1546	Belongs to the CinA family
BK002_RS11835	COG2200	EAL domain
BK002_RS11850	COG3708	Transcriptional regulator
BK002_RS11850	COG2207	Transcriptional regulator
BK002_RS11855	COG2610	gluconate transmembrane transporter activity
BK002_RS11860	COG3622	Belongs to the hyi family
BK002_RS11865	COG0235	Class ii aldolase
BK002_RS11870	COG3395	kinase activity
BK002_RS11875	COG2084	Dehydrogenase
BK002_RS11880	COG1349	DNA-binding transcription factor activity
BK002_RS11895	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BK002_RS11900	COG2223	nitrite transmembrane transporter activity
BK002_RS11935	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BK002_RS11940	COG0683	leucine binding
BK002_RS11955	COG1129	ABC transporter
BK002_RS11970	COG2814	Major facilitator Superfamily
BK002_RS11975	COG0697	spore germination
BK002_RS11985	COG4977	sequence-specific DNA binding
BK002_RS12015	COG2271	Major facilitator Superfamily
BK002_RS12020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BK002_RS12025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BK002_RS12035	COG3395	kinase activity
BK002_RS12040	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BK002_RS12045	COG1349	DNA-binding transcription factor activity
BK002_RS12050	COG0039	L-malate dehydrogenase activity
BK002_RS12060	COG0583	DNA-binding transcription factor activity
BK002_RS12065	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS12080	COG2199	diguanylate cyclase activity
BK002_RS12145	COG0477	Major facilitator Superfamily
BK002_RS12155	COG2070	2-Nitropropane dioxygenase
BK002_RS12160	COG2011	ABC-type metal ion transport system permease component
BK002_RS12180	COG4628	conserved protein (DUF2132)
BK002_RS12195	COG2207	Transcriptional regulator
BK002_RS12225	COG2233	PERMEase
BK002_RS12230	COG3648	Uricase
BK002_RS12230	COG3195	allantoin biosynthetic process
BK002_RS12235	COG2351	hydroxyisourate hydrolase activity
BK002_RS12240	COG1396	sequence-specific DNA binding
BK002_RS12245	COG3550	peptidyl-serine autophosphorylation
BK002_RS12250	COG1649	PFAM Uncharacterised BCR, COG1649
BK002_RS12260	COG3188	usher protein
BK002_RS12295	COG5001	Diguanylate cyclase
BK002_RS12295	COG3300	MHYT domain
BK002_RS12300	COG2819	hydrolase of the alpha beta superfamily
BK002_RS12315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS12315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS12320	COG2814	Major facilitator Superfamily
BK002_RS12330	COG1263	PTS System
BK002_RS12330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BK002_RS12335	COG2186	Transcriptional regulator
BK002_RS12355	COG3835	regulator
BK002_RS12360	COG1929	Belongs to the glycerate kinase type-1 family
BK002_RS12400	COG0583	DNA-binding transcription factor activity
BK002_RS12430	COG3118	belongs to the thioredoxin family
BK002_RS12440	COG1271	oxidase subunit
BK002_RS12445	COG1294	oxidase, subunit
BK002_RS12460	COG0814	amino acid
BK002_RS12465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK002_RS12470	COG0626	cystathionine gamma-synthase activity
BK002_RS12475	COG0583	DNA-binding transcription factor activity
BK002_RS12480	COG0251	oxidation-reduction process
BK002_RS12495	COG1473	amidohydrolase
BK002_RS12505	COG2801	Transposase and inactivated derivatives
BK002_RS12520	COG0667	Aldo Keto reductase
BK002_RS12525	COG3386	PFAM SMP-30 Gluconolaconase
BK002_RS12535	COG0667	Aldo Keto reductase
BK002_RS12545	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BK002_RS12545	COG0456	acetyltransferase
BK002_RS12575	COG1652	LysM domain
BK002_RS12605	COG1609	Transcriptional regulator
BK002_RS12615	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS12630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BK002_RS12640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BK002_RS12645	COG0583	DNA-binding transcription factor activity
BK002_RS12650	COG0583	DNA-binding transcription factor activity
BK002_RS12680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BK002_RS12690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BK002_RS12695	COG3037	sugar-specific permease SgaT UlaA
BK002_RS12705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS12710	COG1609	Transcriptional regulator
BK002_RS12720	COG2223	nitrite transmembrane transporter activity
BK002_RS12750	COG0477	Major facilitator Superfamily
BK002_RS12755	COG4529	Protein conserved in bacteria
BK002_RS12760	COG1902	pentaerythritol trinitrate reductase activity
BK002_RS12770	COG0583	DNA-binding transcription factor activity
BK002_RS12775	COG2070	2-Nitropropane dioxygenase
BK002_RS12785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BK002_RS12795	COG0765	amino acid transport
BK002_RS12840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BK002_RS12865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BK002_RS12880	COG2207	Transcriptional regulator
BK002_RS12890	COG0596	Alpha beta hydrolase
BK002_RS12925	COG1953	Uracil, thiamine, allantoin
BK002_RS12930	COG0402	S-adenosylhomocysteine deaminase activity
BK002_RS12935	COG3706	GGDEF domain
BK002_RS12940	COG1609	Transcriptional regulator
BK002_RS12950	COG0673	inositol 2-dehydrogenase activity
BK002_RS12965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BK002_RS12970	COG1116	anion transmembrane transporter activity
BK002_RS12975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BK002_RS12980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BK002_RS12985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BK002_RS12990	COG0076	glutamate decarboxylase activity
BK002_RS13005	COG2205	protein histidine kinase activity
BK002_RS13015	COG0596	Alpha beta hydrolase
BK002_RS13055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BK002_RS13055	COG0519	Catalyzes the synthesis of GMP from XMP
BK002_RS13075	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BK002_RS13080	COG1285	pathogenesis
BK002_RS13085	COG2814	Major facilitator Superfamily
BK002_RS13090	COG1447	Phosphotransferase system cellobiose-specific component IIA
BK002_RS13095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS13115	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BK002_RS13140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS13145	COG0583	DNA-binding transcription factor activity
BK002_RS13150	COG0243	molybdopterin cofactor binding
BK002_RS13155	COG3781	membrane
BK002_RS13180	COG1764	response to oxidative stress
BK002_RS13190	COG3111	PFAM Bacterial OB fold (BOF) protein
BK002_RS13200	COG2323	membrane
BK002_RS13210	COG0366	Alpha amylase catalytic
BK002_RS13220	COG3685	Protein conserved in bacteria
BK002_RS13230	COG3729	General stress protein
BK002_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS13275	COG0488	(ABC) transporter
BK002_RS13290	COG1064	alcohol dehydrogenase
BK002_RS13295	COG0747	negative chemotaxis
BK002_RS13305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BK002_RS13315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BK002_RS13325	COG2814	Major facilitator Superfamily
BK002_RS13335	COG2326	polyphosphate kinase activity
BK002_RS13350	COG2864	formate dehydrogenase
BK002_RS13355	COG0437	4 iron, 4 sulfur cluster binding
BK002_RS13380	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BK002_RS13390	COG3485	protocatechuate 3,4-dioxygenase
BK002_RS13395	COG4829	muconolactone delta-isomerase
BK002_RS13400	COG4948	Mandelate Racemase Muconate Lactonizing
BK002_RS13405	COG1414	Transcriptional regulator
BK002_RS13425	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BK002_RS13430	COG1140	nitrate reductase beta subunit
BK002_RS13435	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BK002_RS13445	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BK002_RS13470	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BK002_RS13475	COG1178	ABC-type Fe3 transport system permease component
BK002_RS13480	COG1840	ABC-type Fe3 transport system, periplasmic component
BK002_RS13485	COG3842	ATPase activity
BK002_RS13490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BK002_RS13505	COG2211	Major facilitator Superfamily
BK002_RS13525	COG0625	glutathione transferase activity
BK002_RS13535	COG1126	abc transporter atp-binding protein
BK002_RS13540	COG0765	amino acid transport
BK002_RS13550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK002_RS13555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BK002_RS13560	COG1473	amidohydrolase
BK002_RS13565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BK002_RS13570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BK002_RS13595	COG4772	TonB-dependent receptor
BK002_RS13600	COG1228	amidohydrolase
BK002_RS13605	COG3691	Protein conserved in bacteria
BK002_RS13620	COG2130	NADP-dependent
BK002_RS13630	COG1247	-acetyltransferase
BK002_RS13635	COG3238	Protein conserved in bacteria
BK002_RS13645	COG0747	negative chemotaxis
BK002_RS13650	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS13685	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS13690	COG1177	transmembrane transport
BK002_RS13695	COG1176	ABC-type spermidine putrescine transport system, permease component I
BK002_RS13700	COG3842	ATPase activity
BK002_RS13705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BK002_RS13710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK002_RS13715	COG1271	oxidase subunit
BK002_RS13720	COG1294	oxidase, subunit
BK002_RS13740	COG0826	peptidase U32
BK002_RS13750	COG1396	sequence-specific DNA binding
BK002_RS13755	COG3135	benzoate transporter
BK002_RS13760	COG3708	Transcriptional regulator
BK002_RS13760	COG2207	Transcriptional regulator
BK002_RS13765	COG0697	spore germination
BK002_RS13775	COG0500	methyltransferase
BK002_RS13780	COG1275	C4-dicarboxylate transporter malic acid transport protein
BK002_RS13785	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BK002_RS13790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BK002_RS13805	COG2272	Belongs to the type-B carboxylesterase lipase family
BK002_RS13810	COG5383	Protein conserved in bacteria
BK002_RS13815	COG3485	protocatechuate 3,4-dioxygenase
BK002_RS13820	COG3485	protocatechuate 3,4-dioxygenase
BK002_RS13825	COG0583	DNA-binding transcription factor activity
BK002_RS13845	COG3038	cytochrome b561
BK002_RS13865	COG2814	Major facilitator Superfamily
BK002_RS13875	COG0673	inositol 2-dehydrogenase activity
BK002_RS13885	COG2723	6-phospho-beta-galactosidase activity
BK002_RS13920	COG4659	FMN binding
BK002_RS13930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BK002_RS13940	COG0625	glutathione transferase activity
BK002_RS13945	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BK002_RS13960	COG3895	Periplasmic Protein
BK002_RS13975	COG3706	GGDEF domain
BK002_RS13990	COG1566	PFAM secretion protein HlyD family protein
BK002_RS13995	COG1289	transmembrane transporter activity
BK002_RS14000	COG2032	superoxide dismutase activity
BK002_RS14005	COG4989	oxidoreductase activity
BK002_RS14010	COG3313	Fe-S protein
BK002_RS14015	COG1309	transcriptional regulator
BK002_RS14020	COG1902	pentaerythritol trinitrate reductase activity
BK002_RS14025	COG0346	lactoylglutathione lyase activity
BK002_RS14035	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BK002_RS14040	COG0791	NLP P60 protein
BK002_RS14055	COG2814	Major facilitator Superfamily
BK002_RS14070	COG0583	DNA-binding transcription factor activity
BK002_RS14075	COG2814	Major facilitator Superfamily
BK002_RS14080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BK002_RS14085	COG0307	riboflavin synthase, alpha
BK002_RS14125	COG0300	oxidoreductase activity
BK002_RS14145	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BK002_RS14180	COG1349	DNA-binding transcription factor activity
BK002_RS14185	COG0346	lactoylglutathione lyase activity
BK002_RS14210	COG0444	Belongs to the ABC transporter superfamily
BK002_RS14215	COG4608	Belongs to the ABC transporter superfamily
BK002_RS14245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BK002_RS14255	COG1082	Xylose isomerase domain protein TIM barrel
BK002_RS14260	COG2814	Major facilitator Superfamily
BK002_RS14305	COG2200	EAL domain
BK002_RS14325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK002_RS14330	COG2205	protein histidine kinase activity
BK002_RS14345	COG2200	EAL domain
BK002_RS14385	COG0402	S-adenosylhomocysteine deaminase activity
BK002_RS14410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BK002_RS14415	COG0277	FAD linked oxidase domain protein
BK002_RS14435	COG0583	DNA-binding transcription factor activity
BK002_RS14445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BK002_RS14455	COG1250	3-hydroxyacyl-CoA dehydrogenase
BK002_RS14460	COG2610	gluconate transmembrane transporter activity
BK002_RS14465	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS14510	COG4235	cytochrome complex assembly
BK002_RS14510	COG3088	subunit of a heme lyase
BK002_RS14515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BK002_RS14520	COG1138	Cytochrome C-type biogenesis protein
BK002_RS14535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BK002_RS14540	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BK002_RS14545	COG4133	protoheme IX ABC transporter activity
BK002_RS14575	COG3157	Type VI secretion system effector, Hcp
BK002_RS14580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BK002_RS14585	COG1518	maintenance of DNA repeat elements
BK002_RS14595	COG1857	crispr-associated protein
BK002_RS14625	COG1175	transmembrane transport
BK002_RS14635	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BK002_RS14640	COG3383	formate dehydrogenase (NAD+) activity
BK002_RS14680	COG1126	abc transporter atp-binding protein
BK002_RS14685	COG0765	amino acid transport
BK002_RS14705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK002_RS14710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK002_RS14715	COG1120	ATPase activity
BK002_RS14720	COG4774	siderophore transport
BK002_RS14725	COG1116	anion transmembrane transporter activity
BK002_RS14730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BK002_RS14750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BK002_RS14755	COG0583	DNA-binding transcription factor activity
BK002_RS14775	COG2814	Major facilitator Superfamily
BK002_RS14810	COG1414	Transcriptional regulator
BK002_RS14815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BK002_RS14820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK002_RS14825	COG1120	ATPase activity
BK002_RS14835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BK002_RS14840	COG2271	Major facilitator Superfamily
BK002_RS14845	COG1082	Xylose isomerase domain protein TIM barrel
BK002_RS14845	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BK002_RS14850	COG1309	transcriptional regulator
BK002_RS14880	COG1376	ErfK ybiS ycfS ynhG family protein
BK002_RS14895	COG0719	Fe-S assembly protein
BK002_RS14900	COG0396	ATPase activity
BK002_RS14905	COG0719	Fe-S assembly protein
BK002_RS14910	COG0316	Belongs to the HesB IscA family
BK002_RS14930	COG1309	transcriptional regulator
BK002_RS14935	COG1304	FMN binding
BK002_RS14960	COG0583	DNA-binding transcription factor activity
BK002_RS14970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK002_RS14975	COG1120	ATPase activity
BK002_RS15000	COG2261	transglycosylase associated protein
BK002_RS15005	COG2050	protein possibly involved in aromatic compounds catabolism
BK002_RS15010	COG0277	FAD linked oxidase domain protein
BK002_RS15010	COG0247	lactate metabolic process
BK002_RS15015	COG0628	permease
BK002_RS15025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BK002_RS15025	COG0574	Belongs to the PEP-utilizing enzyme family
BK002_RS15040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BK002_RS15045	COG4256	Hemin uptake protein
BK002_RS15055	COG0791	NLP P60 protein
BK002_RS15065	COG0386	Belongs to the glutathione peroxidase family
BK002_RS15085	COG0583	DNA-binding transcription factor activity
BK002_RS15105	COG0072	phenylalanine-tRNA ligase activity
BK002_RS15105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BK002_RS15145	COG3137	Salt-induced outer membrane protein
BK002_RS15150	COG1105	Belongs to the carbohydrate kinase PfkB family
BK002_RS15160	COG3001	Fructosamine kinase
BK002_RS15170	COG2350	Protein conserved in bacteria
BK002_RS15180	COG2353	YceI-like domain
BK002_RS15200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BK002_RS15210	COG0444	Belongs to the ABC transporter superfamily
BK002_RS15215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BK002_RS15220	COG0601	transmembrane transport
BK002_RS15225	COG4166	transmembrane transport
BK002_RS15230	COG2095	MarC family integral membrane protein
BK002_RS15240	COG1454	alcohol dehydrogenase
BK002_RS15240	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS15245	COG1435	thymidine kinase activity
BK002_RS15255	COG2916	Histone family protein nucleoid-structuring protein H-NS
BK002_RS15260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BK002_RS15265	COG0745	RESPONSE REGULATOR receiver
BK002_RS15270	COG1752	Esterase of the alpha-beta hydrolase superfamily
BK002_RS15280	COG0788	formyltetrahydrofolate deformylase activity
BK002_RS15320	COG1522	sequence-specific DNA binding
BK002_RS15330	COG2181	nitrate reductase activity
BK002_RS15335	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BK002_RS15340	COG1140	nitrate reductase beta subunit
BK002_RS15345	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BK002_RS15355	COG2223	nitrite transmembrane transporter activity
BK002_RS15360	COG3850	Histidine kinase
BK002_RS15365	COG2197	response regulator
BK002_RS15370	COG4932	domain protein
BK002_RS15375	COG0243	molybdopterin cofactor binding
BK002_RS15380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BK002_RS15380	COG2146	nitrite reductase [NAD(P)H] activity
BK002_RS15385	COG1116	anion transmembrane transporter activity
BK002_RS15395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BK002_RS15400	COG3707	response regulator
BK002_RS15405	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BK002_RS15415	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BK002_RS15420	COG4572	Cation transport regulator
BK002_RS15425	COG0387	Pfam Sodium calcium exchanger
BK002_RS15445	COG2890	protein-(glutamine-N5) methyltransferase activity
BK002_RS15475	COG0659	secondary active sulfate transmembrane transporter activity
BK002_RS15495	COG0012	GTP binding
BK002_RS15565	COG2885	chlorophyll binding
BK002_RS15585	COG3122	Protein conserved in bacteria
BK002_RS15600	COG0583	DNA-binding transcription factor activity
BK002_RS15630	COG0583	DNA-binding transcription factor activity
BK002_RS15665	COG1882	Formate acetyltransferase
BK002_RS15680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BK002_RS15685	COG0583	DNA-binding transcription factor activity
BK002_RS15730	COG2308	Evidence 4 Homologs of previously reported genes of
BK002_RS15745	COG4774	siderophore transport
BK002_RS15755	COG1619	proteins homologs of microcin C7 resistance protein MccF
BK002_RS15780	COG2719	SpoVR family
BK002_RS15810	COG0179	Fumarylacetoacetate (FAA) hydrolase
BK002_RS15825	COG2894	cell division
BK002_RS15835	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BK002_RS15845	COG3065	identical protein binding
BK002_RS15855	COG1199	ATP-dependent helicase activity
BK002_RS15860	COG0251	oxidation-reduction process
BK002_RS15880	COG1760	l-serine dehydratase
BK002_RS15885	COG2200	EAL domain
BK002_RS15890	COG1253	flavin adenine dinucleotide binding
BK002_RS15895	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS15895	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BK002_RS15900	COG3715	PTS system
BK002_RS15905	COG3716	PTS system mannose fructose sorbose family IID component
BK002_RS15920	COG2226	methyltransferase
BK002_RS15925	COG0768	penicillin binding
BK002_RS15955	COG1414	Transcriptional regulator
BK002_RS15960	COG2814	Major facilitator Superfamily
BK002_RS15980	COG1956	GAF domain-containing protein
BK002_RS15985	COG2995	paraquat-inducible protein a
BK002_RS15990	COG3008	intermembrane lipid transfer
BK002_RS16015	COG2990	Protein conserved in bacteria
BK002_RS16030	COG1276	copper resistance
BK002_RS16035	COG2372	response to copper ion
BK002_RS16045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BK002_RS16050	COG1770	oligopeptidase
BK002_RS16055	COG2979	Protein of unknown function (DUF533)
BK002_RS16060	COG3141	response to X-ray
BK002_RS16070	COG0800	Aldolase
BK002_RS16075	COG0129	dihydroxy-acid dehydratase activity
BK002_RS16080	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BK002_RS16090	COG1737	Transcriptional regulator
BK002_RS16100	COG1560	Kdo2-lipid A biosynthetic process
BK002_RS16105	COG0739	heme binding
BK002_RS16110	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BK002_RS16120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BK002_RS16145	COG0494	nUDIX hydrolase
BK002_RS16155	COG1335	isochorismatase
BK002_RS16160	COG1801	Protein of unknown function DUF72
BK002_RS16165	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BK002_RS16185	COG3102	Protein conserved in bacteria
BK002_RS16195	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BK002_RS16220	COG1172	Belongs to the binding-protein-dependent transport system permease family
BK002_RS16230	COG1879	ABC-type sugar transport system periplasmic component
BK002_RS16245	COG1528	Iron-storage protein
BK002_RS16255	COG2211	Major facilitator Superfamily
BK002_RS16265	COG0477	Major facilitator Superfamily
BK002_RS16280	COG1528	Iron-storage protein
BK002_RS16290	COG0814	amino acid
BK002_RS16295	COG3012	SEC-C Motif Domain Protein
BK002_RS16295	COG3318	Belongs to the UPF0149 family
BK002_RS16330	COG2197	response regulator
BK002_RS16340	COG2197	response regulator
BK002_RS16345	COG1126	abc transporter atp-binding protein
BK002_RS16350	COG0765	amino acid transport
BK002_RS16360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK002_RS16365	COG0366	Alpha amylase catalytic
BK002_RS16395	COG2354	Protein conserved in bacteria
BK002_RS16400	COG0697	spore germination
BK002_RS16405	COG3727	T/G mismatch-specific endonuclease activity
BK002_RS16410	COG0270	DNA (cytosine-5-)-methyltransferase activity
BK002_RS16415	COG1418	mRNA catabolic process
BK002_RS16425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BK002_RS16445	COG0582	viral genome integration into host DNA
BK002_RS16450	COG1169	isochorismate synthase
BK002_RS16455	COG2814	Major facilitator Superfamily
BK002_RS16460	COG1132	(ABC) transporter
BK002_RS16475	COG3433	isochorismatase activity
BK002_RS16475	COG2226	methyltransferase
BK002_RS16475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BK002_RS16495	COG1021	2,3-dihydroxybenzoate-AMP ligase
BK002_RS16500	COG4771	TonB-dependent receptor
BK002_RS16580	COG3504	Conjugal transfer protein
BK002_RS16625	COG2003	Belongs to the UPF0758 family
BK002_RS16720	COG0025	NhaP-type Na H and K H
BK002_RS16725	COG1309	transcriptional regulator
BK002_RS16730	COG0604	alcohol dehydrogenase
BK002_RS16750	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BK002_RS16760	COG0534	Mate efflux family protein
BK002_RS16780	COG3706	GGDEF domain
BK002_RS16805	COG3615	Tellurite resistance protein tehB
BK002_RS16815	COG3300	MHYT domain
BK002_RS16815	COG5001	Diguanylate cyclase
BK002_RS16825	COG0477	Major facilitator Superfamily
BK002_RS16830	COG0095	Lipoate-protein ligase
BK002_RS16835	COG0583	DNA-binding transcription factor activity
BK002_RS16840	COG1942	4-Oxalocrotonate Tautomerase
BK002_RS16850	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BK002_RS16870	COG1289	transmembrane transporter activity
BK002_RS16885	COG2925	Exonuclease
BK002_RS16890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BK002_RS16895	COG0640	Transcriptional regulator
BK002_RS16900	COG0531	amino acid
BK002_RS16910	COG0583	DNA-binding transcription factor activity
BK002_RS16915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BK002_RS16945	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BK002_RS16965	COG1215	transferase activity, transferring glycosyl groups
BK002_RS16970	COG0438	transferase activity, transferring glycosyl groups
BK002_RS17040	COG1088	dTDP-glucose 4,6-dehydratase activity
BK002_RS17085	COG0438	transferase activity, transferring glycosyl groups
BK002_RS17095	COG1442	glycosyl transferase family 8
BK002_RS17095	COG1216	Glycosyl transferase, family 2
BK002_RS17155	COG1253	flavin adenine dinucleotide binding
BK002_RS17160	COG2982	Protein involved in outer membrane biogenesis
BK002_RS17175	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BK002_RS17180	COG0443	Heat shock 70 kDa protein
BK002_RS17185	COG5002	protein histidine kinase activity
BK002_RS17205	COG1301	dicarboxylic acid transport
BK002_RS17230	COG2205	protein histidine kinase activity
BK002_RS17235	COG0745	RESPONSE REGULATOR receiver
BK002_RS17240	COG0826	peptidase U32
BK002_RS17250	COG4608	Belongs to the ABC transporter superfamily
BK002_RS17255	COG0444	Belongs to the ABC transporter superfamily
BK002_RS17260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BK002_RS17265	COG0601	transmembrane transport
BK002_RS17270	COG0747	negative chemotaxis
BK002_RS17275	COG4948	Mandelate Racemase Muconate Lactonizing
BK002_RS17280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BK002_RS17290	COG1070	Carbohydrate kinase
BK002_RS17325	COG1830	Aldolase
BK002_RS17330	COG0351	phosphomethylpyrimidine kinase
BK002_RS17345	COG0583	DNA-binding transcription factor activity
BK002_RS17355	COG2252	PERMEase
BK002_RS17360	COG0583	DNA-binding transcription factor activity
BK002_RS17365	COG5455	response to cobalt ion
BK002_RS17385	COG4807	Protein conserved in bacteria
BK002_RS17395	COG3275	phosphorelay sensor kinase activity
BK002_RS17405	COG1174	glycine betaine transport
BK002_RS17410	COG1125	glycine betaine transport
BK002_RS17415	COG1174	glycine betaine transport
BK002_RS17420	COG1732	Glycine betaine
BK002_RS17425	COG1472	Belongs to the glycosyl hydrolase 3 family
BK002_RS17430	COG0277	FAD linked oxidase domain protein
BK002_RS17440	COG1686	Belongs to the peptidase S11 family
BK002_RS17450	COG0586	Pfam SNARE associated Golgi protein
BK002_RS17455	COG1538	Outer membrane efflux protein
BK002_RS17460	COG2723	6-phospho-beta-galactosidase activity
BK002_RS17475	COG3659	wide pore channel activity
BK002_RS17480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BK002_RS17490	COG1346	cytolysis
BK002_RS17500	COG2949	membrane
BK002_RS17510	COG1129	ABC transporter
BK002_RS17525	COG2311	Membrane
BK002_RS17540	COG4771	TonB-dependent receptor
BK002_RS17545	COG0833	amino acid
BK002_RS17550	COG0583	DNA-binding transcription factor activity
BK002_RS17555	COG2855	membrane
BK002_RS17565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BK002_RS17565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BK002_RS17565	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BK002_RS17570	COG1105	Belongs to the carbohydrate kinase PfkB family
BK002_RS17575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS17575	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS17600	COG1312	Catalyzes the dehydration of D-mannonate
BK002_RS17605	COG0246	Mannitol dehydrogenase
BK002_RS17610	COG0523	cobalamin synthesis protein
BK002_RS17615	COG0671	phosphoesterase, PA-phosphatase related
BK002_RS17620	COG0791	NLP P60 protein
BK002_RS17625	COG2200	EAL domain
BK002_RS17630	COG4166	transmembrane transport
BK002_RS17635	COG4174	ABC transporter (Permease)
BK002_RS17640	COG4239	(ABC) transporter, permease
BK002_RS17645	COG4172	Belongs to the ABC transporter superfamily
BK002_RS17655	COG2814	Major facilitator Superfamily
BK002_RS17660	COG1187	pseudouridine synthase activity
BK002_RS17665	COG1061	Type III restriction enzyme res subunit
BK002_RS17685	COG0494	nUDIX hydrolase
BK002_RS17690	COG1349	DNA-binding transcription factor activity
BK002_RS17715	COG0582	viral genome integration into host DNA
BK002_RS17770	COG0628	permease
BK002_RS17785	COG0659	secondary active sulfate transmembrane transporter activity
BK002_RS17790	COG2239	Acts as a magnesium transporter
BK002_RS17795	COG4615	Cyclic peptide transporter
BK002_RS17800	COG3145	DNA-N1-methyladenine dioxygenase activity
BK002_RS17805	COG2169	Transcriptional regulator
BK002_RS17805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BK002_RS17820	COG2198	Histidine kinase
BK002_RS17820	COG0642	Histidine kinase
BK002_RS17830	COG0784	Response regulator, receiver
BK002_RS17830	COG2205	protein histidine kinase activity
BK002_RS17855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BK002_RS17860	COG0584	glycerophosphoryl diester phosphodiesterase
BK002_RS17865	COG2271	Major facilitator Superfamily
BK002_RS17870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BK002_RS17880	COG0247	lactate metabolic process
BK002_RS17890	COG2271	Major facilitator Superfamily
BK002_RS17900	COG1414	Transcriptional regulator
BK002_RS17915	COG5464	transposase or invertase
BK002_RS17925	COG0318	PFAM AMP-dependent synthetase and ligase
BK002_RS17950	COG1169	isochorismate synthase
BK002_RS17955	COG2153	protein acetylation
BK002_RS17970	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BK002_RS17975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BK002_RS17985	COG0839	Belongs to the complex I subunit 6 family
BK002_RS18030	COG0583	DNA-binding transcription factor activity
BK002_RS18035	COG0436	Aminotransferase
BK002_RS18045	COG0471	metal ion transport
BK002_RS18045	COG0490	domain, Protein
BK002_RS18050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BK002_RS18070	COG0280	phosphate acetyltransferase
BK002_RS18070	COG0857	belongs to the CobB CobQ family
BK002_RS18075	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BK002_RS18080	COG0622	Phosphoesterase
BK002_RS18085	COG0625	glutathione transferase activity
BK002_RS18090	COG0625	glutathione transferase activity
BK002_RS18095	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BK002_RS18100	COG1090	epimerase
BK002_RS18115	COG4598	ABC transporter
BK002_RS18120	COG4160	amino acid transport
BK002_RS18145	COG0163	prenyltransferase activity
BK002_RS18150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BK002_RS18155	COG1286	toxin biosynthetic process
BK002_RS18160	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BK002_RS18165	COG0285	dihydrofolate synthase activity
BK002_RS18175	COG0586	Pfam SNARE associated Golgi protein
BK002_RS18185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BK002_RS18205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BK002_RS18220	COG3101	peptidyl-lysine hydroxylation
BK002_RS18225	COG0730	response to heat
BK002_RS18250	COG2062	phosphohistidine phosphatase, SixA
BK002_RS18265	COG3691	Protein conserved in bacteria
BK002_RS18275	COG2853	Lipoprotein
BK002_RS18280	COG2116	formate transmembrane transporter activity
BK002_RS18300	COG0583	DNA-binding transcription factor activity
BK002_RS18305	COG0590	tRNA wobble adenosine to inosine editing
BK002_RS18310	COG2807	transmembrane transport
BK002_RS18320	COG0436	Aminotransferase
BK002_RS18335	COG3275	phosphorelay sensor kinase activity
BK002_RS18340	COG3279	Response regulator of the LytR AlgR family
BK002_RS18355	COG3961	Belongs to the TPP enzyme family
BK002_RS18360	COG0667	Aldo Keto reductase
BK002_RS18375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BK002_RS18380	COG2199	diguanylate cyclase activity
BK002_RS18380	COG2200	EAL domain
BK002_RS18395	COG3415	Transposase
BK002_RS18400	COG3415	Transposase
BK002_RS18430	COG0583	DNA-binding transcription factor activity
BK002_RS18435	COG0385	Bile acid
BK002_RS18440	COG3530	Putative quorum-sensing-regulated virulence factor
BK002_RS18460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BK002_RS18495	COG4319	ketosteroid isomerase
BK002_RS18505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BK002_RS18510	COG4208	sulfate ABC transporter
BK002_RS18515	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BK002_RS18520	COG4150	thiosulfate binding
BK002_RS18530	COG2837	iron assimilation
BK002_RS18550	COG0860	N-Acetylmuramoyl-L-alanine amidase
BK002_RS18640	COG4810	utilization protein
BK002_RS18650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BK002_RS18655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BK002_RS18660	COG5342	invasion associated locus B
BK002_RS18670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BK002_RS18670	COG0493	'glutamate synthase
BK002_RS18675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK002_RS18685	COG1393	Belongs to the ArsC family
BK002_RS18700	COG0400	carboxylic ester hydrolase activity
BK002_RS18705	COG1444	tRNA N-acetyltransferase activity
BK002_RS18710	COG2321	neutral zinc metallopeptidase
BK002_RS18720	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BK002_RS18730	COG2716	regulation of RNA biosynthetic process
BK002_RS18735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BK002_RS18740	COG0628	permease
BK002_RS18750	COG4783	chaperone-mediated protein folding
BK002_RS18755	COG1393	Belongs to the ArsC family
BK002_RS18770	COG2233	PERMEase
BK002_RS18780	COG2723	6-phospho-beta-galactosidase activity
BK002_RS18795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BK002_RS18810	COG2200	EAL domain
BK002_RS18830	COG0641	radical SAM
BK002_RS18835	COG3119	arylsulfatase activity
BK002_RS18845	COG0516	GMP reductase activity
BK002_RS18845	COG0517	IMP dehydrogenase activity
BK002_RS18855	COG1645	bacterial-type flagellum-dependent swarming motility
BK002_RS18875	COG2976	Protein conserved in bacteria
BK002_RS18905	COG4953	penicillin-binding protein 1C
BK002_RS18910	COG2373	Large extracellular alpha-helical protein
BK002_RS18915	COG2897	thiosulfate sulfurtransferase activity
BK002_RS18935	COG2975	iron-sulfur cluster assembly
BK002_RS18940	COG0633	Ferredoxin
BK002_RS18960	COG0822	iron-sulfur transferase activity
BK002_RS18990	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BK002_RS18995	COG3683	transport system, periplasmic component
BK002_RS19000	COG3711	transcriptional antiterminator
BK002_RS19005	COG2814	Major facilitator Superfamily
BK002_RS19010	COG2017	converts alpha-aldose to the beta-anomer
BK002_RS19015	COG0477	Major facilitator Superfamily
BK002_RS19015	COG2814	Major facilitator Superfamily
BK002_RS19020	COG0457	Tetratricopeptide repeat
BK002_RS19025	COG1940	carbohydrate kinase activity
BK002_RS19030	COG2259	Doxx family
BK002_RS19040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BK002_RS19040	COG1017	nitric oxide dioxygenase activity
BK002_RS19045	COG0347	Belongs to the P(II) protein family
BK002_RS19050	COG2204	response regulator
BK002_RS19055	COG3170	Tfp pilus assembly protein FimV
BK002_RS19060	COG2205	protein histidine kinase activity
BK002_RS19065	COG0047	phosphoribosylformylglycinamidine synthase activity
BK002_RS19065	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BK002_RS19080	COG0560	Phosphoserine phosphatase
BK002_RS19085	COG1737	Transcriptional regulator
BK002_RS19090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BK002_RS19100	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BK002_RS19120	COG0681	Belongs to the peptidase S26 family
BK002_RS19130	COG3086	response to oxidative stress
BK002_RS19135	COG3026	antisigma factor binding
BK002_RS19140	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BK002_RS19155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BK002_RS19165	COG0513	Belongs to the DEAD box helicase family
BK002_RS19180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BK002_RS19185	COG3118	belongs to the thioredoxin family
BK002_RS19190	COG3148	PFAM DTW domain containing protein
BK002_RS19200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BK002_RS19205	COG5544	Lipoprotein
BK002_RS19210	COG0477	Major facilitator Superfamily
BK002_RS19235	COG0542	response to heat
BK002_RS19250	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BK002_RS19255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BK002_RS19265	COG0077	Prephenate dehydratase
BK002_RS19265	COG1605	Chorismate mutase
BK002_RS19275	COG0287	Prephenate dehydrogenase
BK002_RS19275	COG1605	Chorismate mutase
BK002_RS19280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BK002_RS19290	COG2199	diguanylate cyclase activity
BK002_RS19295	COG2885	chlorophyll binding
BK002_RS19330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BK002_RS19335	COG4137	Cytochrome C assembly protein
BK002_RS19340	COG4536	flavin adenine dinucleotide binding
BK002_RS19355	COG0497	DNA recombination
BK002_RS19370	COG2867	negative regulation of translational initiation
BK002_RS19530	COG4695	Portal protein
BK002_RS19570	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BK002_RS19605	COG4974	Belongs to the 'phage' integrase family
BK002_RS19635	COG3708	Transcriptional regulator
BK002_RS19635	COG2207	Transcriptional regulator
BK002_RS19640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK002_RS19675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK002_RS19685	COG0235	Class ii aldolase
BK002_RS19695	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS19710	COG2197	response regulator
BK002_RS19715	COG3539	Fimbrial protein
BK002_RS19725	COG3188	usher protein
BK002_RS19745	COG3121	Chaperone
BK002_RS19750	COG3539	Fimbrial protein
BK002_RS19760	COG3284	Transcriptional regulator
BK002_RS19765	COG0583	DNA-binding transcription factor activity
BK002_RS19775	COG0640	Transcriptional regulator
BK002_RS19780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BK002_RS19795	COG2916	Histone family protein nucleoid-structuring protein H-NS
BK002_RS19810	COG4575	ribosome binding
BK002_RS19815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK002_RS19820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BK002_RS19825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BK002_RS19835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BK002_RS19850	COG4176	ABC-type proline glycine betaine transport system permease component
BK002_RS19860	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BK002_RS19870	COG1846	Transcriptional regulator
BK002_RS19875	COG1566	PFAM secretion protein HlyD family protein
BK002_RS19880	COG2814	Major facilitator Superfamily
BK002_RS19885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BK002_RS19905	COG1238	metal cluster binding
BK002_RS19910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BK002_RS19915	COG2823	Periplasmic or secreted lipoprotein
BK002_RS19945	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BK002_RS19965	COG1546	Belongs to the CinA family
BK002_RS19975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BK002_RS19980	COG1121	(ABC) transporter
BK002_RS19985	COG2951	lytic endotransglycosylase activity
BK002_RS19990	COG3730	PTS system glucitol sorbitol-specific
BK002_RS19995	COG3732	PTS system glucitol sorbitol-specific
BK002_RS20005	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS20010	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS20015	COG1349	DNA-binding transcription factor activity
BK002_RS20040	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BK002_RS20045	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BK002_RS20050	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BK002_RS20055	COG1609	Transcriptional regulator
BK002_RS20060	COG1263	PTS System
BK002_RS20060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BK002_RS20065	COG2723	6-phospho-beta-galactosidase activity
BK002_RS20075	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BK002_RS20085	COG3260	NADH ubiquinone oxidoreductase 20
BK002_RS20090	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BK002_RS20095	COG3261	NADH dehydrogenase
BK002_RS20095	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BK002_RS20100	COG0650	Formate hydrogenlyase subunit 4
BK002_RS20105	COG0651	ATP synthesis coupled electron transport
BK002_RS20110	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BK002_RS20125	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BK002_RS20130	COG0298	carbon dioxide binding
BK002_RS20135	COG0409	Hydrogenase expression formation protein
BK002_RS20140	COG0309	Hydrogenase expression formation protein (HypE)
BK002_RS20150	COG2723	6-phospho-beta-galactosidase activity
BK002_RS20160	COG4580	involved in the transport of maltose and maltodextrins
BK002_RS20165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS20170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS20175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS20180	COG1447	Phosphotransferase system cellobiose-specific component IIA
BK002_RS20185	COG1940	carbohydrate kinase activity
BK002_RS20190	COG1609	Transcriptional regulator
BK002_RS20195	COG0803	Belongs to the bacterial solute-binding protein 9 family
BK002_RS20200	COG1121	(ABC) transporter
BK002_RS20205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BK002_RS20210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BK002_RS20225	COG0679	Auxin Efflux Carrier
BK002_RS20245	COG3720	iron ion transport
BK002_RS20250	COG4558	Periplasmic binding protein
BK002_RS20255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK002_RS20300	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BK002_RS20305	COG0163	prenyltransferase activity
BK002_RS20330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BK002_RS20335	COG1388	LysM domain
BK002_RS20335	COG4942	peptidase
BK002_RS20395	COG2234	aminopeptidase activity
BK002_RS20415	COG0720	synthase
BK002_RS20420	COG0602	queuosine metabolic process
BK002_RS20440	COG3956	TIGRFAM MazG family protein
BK002_RS20445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BK002_RS20455	COG3437	response regulator, receiver
BK002_RS20455	COG3850	Histidine kinase
BK002_RS20455	COG4999	Histidine kinase
BK002_RS20455	COG2205	protein histidine kinase activity
BK002_RS20460	COG1929	Belongs to the glycerate kinase type-1 family
BK002_RS20465	COG4948	Mandelate Racemase Muconate Lactonizing
BK002_RS20470	COG4948	Mandelate Racemase Muconate Lactonizing
BK002_RS20475	COG2271	Major facilitator Superfamily
BK002_RS20480	COG0716	FMN binding
BK002_RS20485	COG0564	pseudouridine synthase activity
BK002_RS20490	COG3098	single-species biofilm formation
BK002_RS20505	COG1611	Belongs to the LOG family
BK002_RS20510	COG0814	amino acid
BK002_RS20515	COG1760	l-serine dehydratase
BK002_RS20520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BK002_RS20530	COG0477	Major facilitator Superfamily
BK002_RS20535	COG1464	Belongs to the NlpA lipoprotein family
BK002_RS20540	COG2011	ABC-type metal ion transport system permease component
BK002_RS20545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BK002_RS20560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BK002_RS20580	COG1454	alcohol dehydrogenase
BK002_RS20585	COG0235	Class ii aldolase
BK002_RS20590	COG0738	Major facilitator superfamily
BK002_RS20610	COG1349	DNA-binding transcription factor activity
BK002_RS20620	COG2363	Small membrane protein
BK002_RS20625	COG0583	DNA-binding transcription factor activity
BK002_RS20635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BK002_RS20640	COG2166	iron-sulfur cluster assembly
BK002_RS20645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BK002_RS20650	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BK002_RS20685	COG2885	chlorophyll binding
BK002_RS20890	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BK002_RS20920	COG1012	belongs to the aldehyde dehydrogenase family
BK002_RS20920	COG1454	alcohol dehydrogenase
BK002_RS20925	COG4656	Part of a membrane complex involved in electron transport
BK002_RS20955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BK002_RS20960	COG0860	N-Acetylmuramoyl-L-alanine amidase
BK002_RS20965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BK002_RS20965	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BK002_RS20975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BK002_RS20980	COG1074	ATP-dependent DNA helicase activity
BK002_RS20985	COG1025	Belongs to the peptidase M16 family
BK002_RS20990	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BK002_RS20995	COG4967	type IV pilus modification protein PilV
BK002_RS21005	COG4795	General secretion pathway protein
BK002_RS21010	COG2165	general secretion pathway protein
BK002_RS21045	COG0861	Integral membrane protein TerC family
BK002_RS21055	COG0667	Aldo Keto reductase
BK002_RS21075	COG1609	Transcriptional regulator
BK002_RS21085	COG2186	Transcriptional regulator
BK002_RS21090	COG2723	6-phospho-beta-galactosidase activity
BK002_RS21095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS21100	COG1609	Transcriptional regulator
BK002_RS21110	COG0583	DNA-binding transcription factor activity
BK002_RS21115	COG1794	racemase activity, acting on amino acids and derivatives
BK002_RS21120	COG1917	Cupin 2, conserved barrel domain protein
BK002_RS21125	COG1175	transmembrane transport
BK002_RS21135	COG3842	ATPase activity
BK002_RS21170	COG2814	Major facilitator Superfamily
BK002_RS21175	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS21180	COG0823	Involved in the tonB-independent uptake of proteins
BK002_RS21190	COG0183	Belongs to the thiolase family
BK002_RS21205	COG0814	amino acid
BK002_RS21210	COG0667	Aldo Keto reductase
BK002_RS21260	COG0697	spore germination
BK002_RS21265	COG1846	Transcriptional regulator
BK002_RS21270	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BK002_RS21275	COG0582	viral genome integration into host DNA
BK002_RS21280	COG4974	Belongs to the 'phage' integrase family
BK002_RS21290	COG3539	Fimbrial protein
BK002_RS21295	COG3121	Chaperone
BK002_RS21300	COG3188	usher protein
BK002_RS21305	COG3539	Fimbrial protein
BK002_RS21310	COG3539	Fimbrial protein
BK002_RS21315	COG3539	Fimbrial protein
BK002_RS21325	COG2388	GCN5-related N-acetyl-transferase
BK002_RS21330	COG3592	Divergent 4Fe-4S mono-cluster
BK002_RS21345	COG1289	transmembrane transporter activity
BK002_RS21350	COG1538	Outer membrane efflux protein
BK002_RS21365	COG1393	Belongs to the ArsC family
BK002_RS21370	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BK002_RS21410	COG0667	Aldo Keto reductase
BK002_RS21425	COG2814	Major facilitator Superfamily
BK002_RS21435	COG4942	peptidase
BK002_RS21440	COG0583	DNA-binding transcription factor activity
BK002_RS21445	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BK002_RS21455	COG1811	Na channel or pump
BK002_RS21475	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BK002_RS21485	COG4974	Belongs to the 'phage' integrase family
BK002_RS21490	COG0716	FMN binding
BK002_RS21500	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BK002_RS21510	COG1272	protein, Hemolysin III
BK002_RS21520	COG1737	Transcriptional regulator
BK002_RS21525	COG2723	6-phospho-beta-galactosidase activity
BK002_RS21545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BK002_RS21550	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS21570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BK002_RS21575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BK002_RS21580	COG0006	proline dipeptidase activity
BK002_RS21600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BK002_RS21605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BK002_RS21620	COG2968	Membrane
BK002_RS21630	COG0668	transmembrane transport
BK002_RS21635	COG0191	fructose-bisphosphate aldolase activity
BK002_RS21650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BK002_RS21655	COG0501	Belongs to the peptidase M48B family
BK002_RS21690	COG2814	Major facilitator Superfamily
BK002_RS21700	COG2356	endonuclease I
BK002_RS21705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BK002_RS21710	COG0189	ligase activity
BK002_RS21730	COG2805	Type II/IV secretion system protein
BK002_RS21735	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BK002_RS21740	COG0762	integral membrane protein
BK002_RS21755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BK002_RS21770	COG4214	carbohydrate transport
BK002_RS21780	COG3171	Protein conserved in bacteria
BK002_RS21790	COG1194	a g-specific adenine glycosylase
BK002_RS21805	COG2211	Major facilitator Superfamily
BK002_RS21810	COG1982	Orn Lys Arg decarboxylase major
BK002_RS21815	COG1811	Na channel or pump
BK002_RS21840	COG3188	usher protein
BK002_RS21845	COG3121	Chaperone
BK002_RS21850	COG3121	Chaperone
BK002_RS21865	COG3121	Chaperone
BK002_RS21880	COG0626	cystathionine gamma-synthase activity
BK002_RS21885	COG0583	DNA-binding transcription factor activity
BK002_RS21905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BK002_RS21910	COG0754	glutathionylspermidine amidase activity
BK002_RS21925	COG0625	glutathione transferase activity
BK002_RS21950	COG2211	Major facilitator Superfamily
BK002_RS21955	COG0848	biopolymer transport protein
BK002_RS21965	COG0626	cystathionine gamma-synthase activity
BK002_RS21970	COG0586	Pfam SNARE associated Golgi protein
BK002_RS21975	COG2207	Transcriptional regulator
BK002_RS21980	COG1979	alcohol dehydrogenase
BK002_RS21985	COG0656	L-ascorbic acid biosynthetic process
BK002_RS21995	COG1032	radical SAM domain protein
BK002_RS22000	COG2132	Multicopper oxidase
BK002_RS22005	COG0204	Acyl-transferase
BK002_RS22010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BK002_RS22015	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BK002_RS22020	COG3111	PFAM Bacterial OB fold (BOF) protein
BK002_RS22030	COG0642	Histidine kinase
BK002_RS22035	COG2249	NAD(P)H dehydrogenase (quinone) activity
BK002_RS22040	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BK002_RS22050	COG3150	esterase
BK002_RS22055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BK002_RS22060	COG3151	Protein conserved in bacteria
BK002_RS22065	COG0494	nUDIX hydrolase
BK002_RS22080	COG0754	glutathionylspermidine amidase activity
BK002_RS22085	COG3384	dioxygenase
BK002_RS22100	COG2960	long-chain fatty acid transporting porin activity
BK002_RS22125	COG3025	triphosphatase activity
BK002_RS22130	COG4991	sh3 domain protein
BK002_RS22145	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BK002_RS22215	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BK002_RS22220	COG0358	DNA primase activity
BK002_RS22225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BK002_RS22260	COG2003	Belongs to the UPF0758 family
BK002_RS22275	COG3468	outer membrane autotransporter barrel domain protein
BK002_RS22280	COG2378	regulation of single-species biofilm formation
BK002_RS22290	COG3596	GTP binding
BK002_RS22310	COG0210	DNA helicase
BK002_RS22360	COG4983	Phage plasmid primase, P4 family domain protein
BK002_RS22390	COG2200	EAL domain
BK002_RS22395	COG3539	Fimbrial protein
BK002_RS22400	COG3539	Fimbrial protein
BK002_RS22405	COG3539	Fimbrial protein
BK002_RS22465	COG2197	response regulator
BK002_RS22470	COG2205	protein histidine kinase activity
BK002_RS22470	COG0784	Response regulator, receiver
BK002_RS22470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BK002_RS22470	COG2198	Histidine kinase
BK002_RS22480	COG3247	response to pH
BK002_RS22550	COG2376	Dihydroxyacetone kinase
BK002_RS22555	COG1461	Dihydroxyacetone kinase
BK002_RS22570	COG2375	cellular response to nickel ion
BK002_RS22575	COG1695	Transcriptional regulator
BK002_RS22625	COG1902	pentaerythritol trinitrate reductase activity
BK002_RS22625	COG0446	pyridine nucleotide-disulphide oxidoreductase
BK002_RS22645	COG1451	nucleotide metabolic process
BK002_RS22650	COG0673	inositol 2-dehydrogenase activity
BK002_RS22655	COG0861	Integral membrane protein TerC family
BK002_RS22670	COG2721	sulfolactate sulfo-lyase activity
BK002_RS22680	COG2271	Major facilitator Superfamily
BK002_RS22685	COG2186	Transcriptional regulator
BK002_RS22690	COG0586	Pfam SNARE associated Golgi protein
BK002_RS22700	COG1422	Protein of unknown function (DUF1090)
BK002_RS22705	COG4575	ribosome binding
BK002_RS22710	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BK002_RS22720	COG2259	Doxx family
BK002_RS22725	COG0435	Glutathione S-transferase
BK002_RS22730	COG3152	Membrane
BK002_RS22735	COG0583	DNA-binding transcription factor activity
BK002_RS22740	COG1741	Belongs to the pirin family
BK002_RS22765	COG1929	Belongs to the glycerate kinase type-1 family
BK002_RS22770	COG2084	Dehydrogenase
BK002_RS22780	COG2271	Major facilitator Superfamily
BK002_RS22785	COG2721	sulfolactate sulfo-lyase activity
BK002_RS22790	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BK002_RS22810	COG2823	Periplasmic or secreted lipoprotein
BK002_RS22815	COG0701	Predicted permease
BK002_RS22820	COG0702	epimerase
BK002_RS22825	COG0693	protein deglycase activity
BK002_RS22840	COG3153	acetyltransferase
BK002_RS22845	COG3154	lipid carrier protein
BK002_RS22850	COG0826	peptidase U32
BK002_RS22855	COG0826	peptidase U32
BK002_RS22860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BK002_RS22865	COG0814	amino acid
BK002_RS22910	COG0195	Participates in both transcription termination and antitermination
BK002_RS22950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BK002_RS22960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BK002_RS22965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BK002_RS22975	COG1534	Rna-binding protein
BK002_RS22985	COG2027	D-alanyl-D-alanine carboxypeptidase
BK002_RS22995	COG0697	spore germination
BK002_RS23010	COG0142	geranyltranstransferase activity
BK002_RS23015	COG3423	Transcriptional regulator
BK002_RS23025	COG5007	Belongs to the BolA IbaG family
BK002_RS23030	COG3113	response to antibiotic
BK002_RS23035	COG2854	intermembrane phospholipid transfer
BK002_RS23040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BK002_RS23045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BK002_RS23050	COG1127	ABC transporter
BK002_RS23055	COG0530	calcium, potassium:sodium antiporter activity
BK002_RS23065	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BK002_RS23070	COG3117	lipopolysaccharide transmembrane transporter activity
BK002_RS23075	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BK002_RS23080	COG1137	ATPase activity
BK002_RS23085	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BK002_RS23090	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BK002_RS23095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS23105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BK002_RS23110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BK002_RS23115	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BK002_RS23120	COG5002	protein histidine kinase activity
BK002_RS23120	COG2198	Histidine kinase
BK002_RS23120	COG0784	Response regulator, receiver
BK002_RS23125	COG1312	Catalyzes the dehydration of D-mannonate
BK002_RS23130	COG1063	alcohol dehydrogenase
BK002_RS23135	COG2271	Major facilitator Superfamily
BK002_RS23140	COG1242	4 iron, 4 sulfur cluster binding
BK002_RS23145	COG0067	glutamate synthase
BK002_RS23145	COG0070	glutamate synthase
BK002_RS23145	COG0069	glutamate synthase activity
BK002_RS23150	COG0493	'glutamate synthase
BK002_RS23160	COG2969	positive regulation of protein catabolic process
BK002_RS23165	COG0625	glutathione transferase activity
BK002_RS23185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BK002_RS23190	COG3105	Protein conserved in bacteria
BK002_RS23195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BK002_RS23200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BK002_RS23225	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BK002_RS23230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BK002_RS23235	COG0471	metal ion transport
BK002_RS23270	COG2732	(Barnase) inhibitor
BK002_RS23275	COG1289	transmembrane transporter activity
BK002_RS23290	COG0583	DNA-binding transcription factor activity
BK002_RS23295	COG0312	modulator of DNA gyrase
BK002_RS23300	COG3164	Protein of unknown function
BK002_RS23305	COG1530	ribonuclease E activity
BK002_RS23315	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BK002_RS23320	COG1792	Involved in formation and maintenance of cell shape
BK002_RS23325	COG1077	Cell shape determining protein MreB Mrl
BK002_RS23330	COG2200	EAL domain
BK002_RS23330	COG2199	diguanylate cyclase activity
BK002_RS23355	COG0511	ligase activity, forming carbon-carbon bonds
BK002_RS23360	COG0439	Biotin carboxylase
BK002_RS23365	COG3924	membrane
BK002_RS23370	COG4145	pantothenate transmembrane transporter activity
BK002_RS23390	COG1309	transcriptional regulator
BK002_RS23395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BK002_RS23400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK002_RS23435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BK002_RS23455	COG0551	DNA topoisomerase type I activity
BK002_RS23465	COG0758	DNA mediated transformation
BK002_RS23495	COG3036	rescue of stalled ribosome
BK002_RS23500	COG0789	Transcriptional regulator
BK002_RS23515	COG0202	RNA polymerase activity
BK002_RS23540	COG0201	protein transport
BK002_RS23605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BK002_RS23620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BK002_RS23645	COG0051	transcription antitermination factor activity, RNA binding
BK002_RS23700	COG2964	Protein conserved in bacteria
BK002_RS23705	COG0545	Peptidyl-prolyl cis-trans isomerase
BK002_RS23715	COG1047	Peptidyl-prolyl cis-trans
BK002_RS23720	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BK002_RS23735	COG0488	(ABC) transporter
BK002_RS23740	COG0429	hydrolase of the alpha beta-hydrolase fold
BK002_RS23750	COG3954	Phosphoribulokinase
BK002_RS23755	COG1765	OsmC-like protein
BK002_RS23765	COG1289	transmembrane transporter activity
BK002_RS23770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BK002_RS23795	COG0738	Major facilitator superfamily
BK002_RS23800	COG0402	S-adenosylhomocysteine deaminase activity
BK002_RS23805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BK002_RS23830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BK002_RS23835	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BK002_RS23840	COG3266	domain, Protein
BK002_RS23855	COG4796	Type ii and iii secretion system protein
BK002_RS23880	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BK002_RS23885	COG0494	nUDIX hydrolase
BK002_RS23895	COG1011	Hydrolase
BK002_RS23900	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BK002_RS23925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BK002_RS23930	COG2183	response to ionizing radiation
BK002_RS23935	COG1918	ferrous iron import across plasma membrane
BK002_RS23960	COG1040	competence protein
BK002_RS23970	COG2610	gluconate transmembrane transporter activity
BK002_RS23975	COG1640	4-alpha-glucanotransferase
BK002_RS23980	COG0058	SHG alpha-glucan phosphorylase activity
BK002_RS23990	COG1349	DNA-binding transcription factor activity
BK002_RS24005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BK002_RS24010	COG0058	SHG alpha-glucan phosphorylase activity
BK002_RS24035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BK002_RS24045	COG2610	gluconate transmembrane transporter activity
BK002_RS24050	COG3265	gluconokinase activity
BK002_RS24055	COG1609	Transcriptional regulator
BK002_RS24060	COG1741	Belongs to the pirin family
BK002_RS24065	COG0673	inositol 2-dehydrogenase activity
BK002_RS24075	COG1247	-acetyltransferase
BK002_RS24080	COG0405	Gamma-glutamyltransferase
BK002_RS24090	COG0584	glycerophosphoryl diester phosphodiesterase
BK002_RS24140	COG0559	Belongs to the binding-protein-dependent transport system permease family
BK002_RS24145	COG0683	leucine binding
BK002_RS24155	COG0683	leucine binding
BK002_RS24170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BK002_RS24185	COG2177	Part of the ABC transporter FtsEX involved in
BK002_RS24190	COG2884	Cell division ATP-binding protein ftsE
BK002_RS24195	COG0552	protein localization to endoplasmic reticulum
BK002_RS24200	COG0742	ribosomal rna small subunit methyltransferase
BK002_RS24205	COG3776	membrane
BK002_RS24215	COG3714	YhhN family
BK002_RS24230	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BK002_RS24240	COG0477	Major facilitator Superfamily
BK002_RS24245	COG0628	permease
BK002_RS24285	COG3479	Phenolic acid decarboxylase
BK002_RS24295	COG0747	negative chemotaxis
BK002_RS24300	COG0601	transmembrane transport
BK002_RS24305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BK002_RS24315	COG1124	(ABC) transporter
BK002_RS24325	COG2239	Acts as a magnesium transporter
BK002_RS24330	COG2081	HI0933 family
BK002_RS24335	COG0306	phosphate transporter
BK002_RS24345	COG0589	response to stress
BK002_RS24365	COG0671	phosphoesterase, PA-phosphatase related
BK002_RS24370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BK002_RS24375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BK002_RS24385	COG1454	alcohol dehydrogenase
BK002_RS24395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BK002_RS24400	COG1028	Short-chain dehydrogenase reductase Sdr
BK002_RS24405	COG0583	DNA-binding transcription factor activity
BK002_RS24410	COG1295	ribonuclease BN
BK002_RS24415	COG0477	Major facilitator Superfamily
BK002_RS24420	COG2982	Protein involved in outer membrane biogenesis
BK002_RS24430	COG0612	Peptidase, M16
BK002_RS24440	COG2199	diguanylate cyclase activity
BK002_RS24440	COG2200	EAL domain
BK002_RS24445	COG0457	Tetratricopeptide repeat
BK002_RS24445	COG3118	belongs to the thioredoxin family
BK002_RS24450	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BK002_RS24455	COG1215	transferase activity, transferring glycosyl groups
BK002_RS24485	COG2194	sulfuric ester hydrolase activity
BK002_RS24500	COG0457	Tetratricopeptide repeat
BK002_RS24505	COG1215	transferase activity, transferring glycosyl groups
BK002_RS24515	COG2894	cell division
BK002_RS24530	COG4608	Belongs to the ABC transporter superfamily
BK002_RS24535	COG0444	Belongs to the ABC transporter superfamily
BK002_RS24540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BK002_RS24545	COG0601	transmembrane transport
BK002_RS24550	COG0747	negative chemotaxis
BK002_RS24575	COG2223	nitrite transmembrane transporter activity
BK002_RS24580	COG5571	outer membrane autotransporter
BK002_RS24585	COG2818	Glycosylase
BK002_RS24590	COG0456	acetyltransferase
BK002_RS24595	COG0243	molybdopterin cofactor binding
BK002_RS24600	COG2885	chlorophyll binding
BK002_RS24605	COG1609	Transcriptional regulator
BK002_RS24615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BK002_RS24635	COG2814	Major facilitator Superfamily
BK002_RS24640	COG2944	sequence-specific DNA binding
BK002_RS24645	COG1278	Cold shock
BK002_RS24685	COG3274	enterobacterial common antigen metabolic process
BK002_RS24690	COG4682	membrane
BK002_RS24695	COG4682	membrane
BK002_RS24710	COG4213	ABC transporter substrate-binding protein
BK002_RS24720	COG4214	carbohydrate transport
BK002_RS24725	COG1609	Transcriptional regulator
BK002_RS24725	COG2207	Transcriptional regulator
BK002_RS24730	COG2992	FlgJ-related protein
BK002_RS24735	COG0366	Alpha amylase catalytic
BK002_RS24740	COG3977	Valine--pyruvate aminotransferase
BK002_RS24745	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BK002_RS24750	COG1414	Transcriptional regulator
BK002_RS24755	COG3276	selenocysteine insertion sequence binding
BK002_RS24765	COG0625	glutathione transferase activity
BK002_RS24785	COG3722	fumarate hydratase activity
BK002_RS24805	COG2186	Transcriptional regulator
BK002_RS24815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BK002_RS24835	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BK002_RS24840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BK002_RS24850	COG4942	peptidase
BK002_RS24855	COG2861	carbohydrate metabolic process
BK002_RS24860	COG0463	Glycosyl transferase, family 2
BK002_RS24870	COG0156	8-amino-7-oxononanoate synthase activity
BK002_RS24885	COG0859	PFAM glycosyl transferase family 9
BK002_RS24910	COG0859	PFAM glycosyl transferase family 9
BK002_RS24920	COG0438	transferase activity, transferring glycosyl groups
BK002_RS24925	COG1216	Glycosyl transferase, family 2
BK002_RS24930	COG1519	Transferase
BK002_RS24965	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BK002_RS24995	COG0842	Transport permease protein
BK002_RS25000	COG1131	(ABC) transporter
BK002_RS25020	COG1561	YicC-like family, N-terminal region
BK002_RS25025	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BK002_RS25030	COG2169	Transcriptional regulator
BK002_RS25030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BK002_RS25040	COG2860	membrane
BK002_RS25060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BK002_RS25065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BK002_RS25070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BK002_RS25075	COG1494	fructose-1,6-bisphosphatase
BK002_RS25085	COG3152	Membrane
BK002_RS25110	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BK002_RS25130	COG0786	glutamate:sodium symporter activity
BK002_RS25135	COG2233	PERMEase
BK002_RS25140	COG2982	Protein involved in outer membrane biogenesis
BK002_RS25145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BK002_RS25145	COG1263	PTS System
BK002_RS25150	COG1486	melibiose metabolic process
BK002_RS25160	COG1501	Belongs to the glycosyl hydrolase 31 family
BK002_RS25165	COG2211	Major facilitator Superfamily
BK002_RS25195	COG1064	alcohol dehydrogenase
BK002_RS25205	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BK002_RS25220	COG1464	Belongs to the NlpA lipoprotein family
BK002_RS25245	COG0583	DNA-binding transcription factor activity
BK002_RS25280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BK002_RS25290	COG2814	Major facilitator Superfamily
BK002_RS25300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BK002_RS25300	COG1263	PTS System
BK002_RS25305	COG0697	spore germination
BK002_RS25320	COG2828	Protein conserved in bacteria
BK002_RS25325	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BK002_RS25330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BK002_RS25335	COG0583	DNA-binding transcription factor activity
BK002_RS25340	COG3384	dioxygenase
BK002_RS25350	COG1609	Transcriptional regulator
BK002_RS25360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS25360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BK002_RS25365	COG1447	Phosphotransferase system cellobiose-specific component IIA
BK002_RS25370	COG4580	involved in the transport of maltose and maltodextrins
BK002_RS25395	COG2188	Transcriptional regulator
BK002_RS25435	COG2271	Major facilitator Superfamily
BK002_RS25445	COG2197	response regulator
BK002_RS25450	COG0440	acetolactate synthase activity
BK002_RS25455	COG0028	Belongs to the TPP enzyme family
BK002_RS25485	COG2814	Major facilitator Superfamily
BK002_RS25490	COG0583	DNA-binding transcription factor activity
BK002_RS25500	COG2610	gluconate transmembrane transporter activity
BK002_RS25520	COG2149	membrane
BK002_RS25535	COG2188	Transcriptional regulator
BK002_RS25545	COG3645	SOS response
BK002_RS25560	COG5645	(Lipo)protein
BK002_RS25565	COG0823	Involved in the tonB-independent uptake of proteins
BK002_RS25570	COG2271	Major facilitator Superfamily
BK002_RS25580	COG0800	Aldolase
BK002_RS25585	COG3734	2-keto-3-deoxy-galactonokinase
BK002_RS25590	COG2186	Transcriptional regulator
BK002_RS25605	COG0561	phosphatase activity
BK002_RS25610	COG0187	DNA topoisomerase II activity
BK002_RS25640	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BK002_RS25670	COG2091	lysine biosynthetic process via aminoadipic acid
BK002_RS25675	COG0431	NADPH-dependent FMN reductase
BK002_RS25680	COG2252	PERMEase
BK002_RS25685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BK002_RS25690	COG0363	glucosamine-6-phosphate deaminase activity
BK002_RS25695	COG2382	esterase
BK002_RS25705	COG0704	Plays a role in the regulation of phosphate uptake
BK002_RS25710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BK002_RS25715	COG0581	inorganic phosphate transmembrane transporter activity
BK002_RS25720	COG0573	inorganic phosphate transmembrane transporter activity
BK002_RS25725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BK002_RS25730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BK002_RS25780	COG3312	ion transport
BK002_RS25815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BK002_RS25825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BK002_RS25840	COG1278	Cold shock
BK002_RS25885	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BK002_RS25955	COG1702	phosphate starvation-inducible protein PhoH
BK002_RS25960	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BK002_RS26045	COG3941	tape measure
BK002_RS26135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BK002_RS26140	COG1475	DNA binding
BK002_RS26145	COG1475	DNA binding
BK002_RS26250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BK002_RS26315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BK002_RS26420	COG0616	signal peptide processing
BK002_RS26560	COG4974	Belongs to the 'phage' integrase family
BK002_RS26615	COG0789	Transcriptional regulator
BK002_RS26650	COG5001	Diguanylate cyclase
BK002_RS26650	COG3300	MHYT domain
BK002_RS26720	COG5001	Diguanylate cyclase
BK002_RS26745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BK002_RS26760	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BK002_RS26860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BK002_RS26945	COG1192	Involved in chromosome partitioning
BK002_RS26990	COG3842	ATPase activity
BK002_RS27005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BK002_RS27010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BK002_RS27060	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BK002_RS27100	COG1660	Displays ATPase and GTPase activities
BK002_RS27185	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BK002_RS27380	COG5499	transcription regulator containing HTH domain
BK002_RS27450	COG1475	DNA binding
BK002_RS27545	COG3344	reverse transcriptase
BK002_RS27565	COG1192	Involved in chromosome partitioning
BK002_RS27625	COG5290	Psort location Cytoplasmic, score
BK002_RS27675	COG2801	Transposase and inactivated derivatives
BK002_RS27685	COG2801	Transposase and inactivated derivatives
BK002_RS27700	COG4172	Belongs to the ABC transporter superfamily
BK002_RS27715	COG0601	transmembrane transport
BK002_RS27720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BK002_RS27750	COG1595	DNA-templated transcription, initiation
BK002_RS27755	COG3712	iron ion homeostasis
BK002_RS27760	COG4772	TonB-dependent receptor
BK002_RS27765	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BK002_RS27770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK002_RS27775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BK002_RS27780	COG1120	ATPase activity
BK002_RS27785	COG3436	PFAM IS66 Orf2 family protein
BK002_RS27810	COG1609	Transcriptional regulator
BK002_RS27820	COG2223	nitrite transmembrane transporter activity
BK002_RS27870	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BK002_RS27910	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity