locus-tag	class	description
AXK16_RS00005	COG1464	Belongs to the NlpA lipoprotein family
AXK16_RS00020	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AXK16_RS00030	COG1064	alcohol dehydrogenase
AXK16_RS00065	COG2211	Major facilitator Superfamily
AXK16_RS00070	COG1501	Belongs to the glycosyl hydrolase 31 family
AXK16_RS00080	COG1486	melibiose metabolic process
AXK16_RS00085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXK16_RS00085	COG1263	PTS System
AXK16_RS00090	COG2982	Protein involved in outer membrane biogenesis
AXK16_RS00095	COG2233	PERMEase
AXK16_RS00100	COG0786	glutamate:sodium symporter activity
AXK16_RS00115	COG3074	FtsZ-dependent cytokinesis
AXK16_RS00120	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AXK16_RS00145	COG3152	Membrane
AXK16_RS00155	COG1494	fructose-1,6-bisphosphatase
AXK16_RS00160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AXK16_RS00165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXK16_RS00190	COG2860	membrane
AXK16_RS00200	COG2169	Transcriptional regulator
AXK16_RS00200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXK16_RS00205	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AXK16_RS00210	COG1561	YicC-like family, N-terminal region
AXK16_RS00235	COG1131	(ABC) transporter
AXK16_RS00240	COG0842	Transport permease protein
AXK16_RS00265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXK16_RS00300	COG1519	Transferase
AXK16_RS00305	COG1216	Glycosyl transferase, family 2
AXK16_RS00310	COG0438	transferase activity, transferring glycosyl groups
AXK16_RS00320	COG0859	PFAM glycosyl transferase family 9
AXK16_RS00345	COG0859	PFAM glycosyl transferase family 9
AXK16_RS00360	COG0156	8-amino-7-oxononanoate synthase activity
AXK16_RS00370	COG0463	Glycosyl transferase, family 2
AXK16_RS00375	COG2861	carbohydrate metabolic process
AXK16_RS00380	COG4942	peptidase
AXK16_RS00390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXK16_RS00395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXK16_RS00415	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AXK16_RS00445	COG3722	fumarate hydratase activity
AXK16_RS00470	COG0625	glutathione transferase activity
AXK16_RS00480	COG3276	selenocysteine insertion sequence binding
AXK16_RS00485	COG1414	Transcriptional regulator
AXK16_RS00490	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXK16_RS00495	COG3977	Valine--pyruvate aminotransferase
AXK16_RS00500	COG0366	Alpha amylase catalytic
AXK16_RS00510	COG2992	FlgJ-related protein
AXK16_RS00515	COG1609	Transcriptional regulator
AXK16_RS00515	COG2207	Transcriptional regulator
AXK16_RS00520	COG4214	carbohydrate transport
AXK16_RS00530	COG4213	ABC transporter substrate-binding protein
AXK16_RS00550	COG4682	membrane
AXK16_RS00555	COG4682	membrane
AXK16_RS00560	COG3274	enterobacterial common antigen metabolic process
AXK16_RS00600	COG1278	Cold shock
AXK16_RS00605	COG2944	sequence-specific DNA binding
AXK16_RS00610	COG2814	Major facilitator Superfamily
AXK16_RS00630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXK16_RS00640	COG1609	Transcriptional regulator
AXK16_RS00645	COG2885	chlorophyll binding
AXK16_RS00650	COG0243	molybdopterin cofactor binding
AXK16_RS00655	COG0456	acetyltransferase
AXK16_RS00660	COG2818	Glycosylase
AXK16_RS00665	COG5571	outer membrane autotransporter
AXK16_RS00670	COG2223	nitrite transmembrane transporter activity
AXK16_RS00715	COG0747	negative chemotaxis
AXK16_RS00720	COG0601	transmembrane transport
AXK16_RS00725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXK16_RS00730	COG0444	Belongs to the ABC transporter superfamily
AXK16_RS00735	COG4608	Belongs to the ABC transporter superfamily
AXK16_RS00760	COG1215	transferase activity, transferring glycosyl groups
AXK16_RS00765	COG0457	Tetratricopeptide repeat
AXK16_RS00780	COG2194	sulfuric ester hydrolase activity
AXK16_RS00810	COG1215	transferase activity, transferring glycosyl groups
AXK16_RS00815	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AXK16_RS00820	COG3118	belongs to the thioredoxin family
AXK16_RS00820	COG0457	Tetratricopeptide repeat
AXK16_RS00825	COG2200	EAL domain
AXK16_RS00825	COG2199	diguanylate cyclase activity
AXK16_RS00835	COG0612	Peptidase, M16
AXK16_RS00850	COG2982	Protein involved in outer membrane biogenesis
AXK16_RS00855	COG0477	Major facilitator Superfamily
AXK16_RS00865	COG0583	DNA-binding transcription factor activity
AXK16_RS00870	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS00875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXK16_RS00885	COG1454	alcohol dehydrogenase
AXK16_RS00895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXK16_RS00900	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AXK16_RS00905	COG0671	phosphoesterase, PA-phosphatase related
AXK16_RS00925	COG0589	response to stress
AXK16_RS00940	COG2081	HI0933 family
AXK16_RS00945	COG2239	Acts as a magnesium transporter
AXK16_RS00955	COG1124	(ABC) transporter
AXK16_RS00965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXK16_RS00970	COG0601	transmembrane transport
AXK16_RS00975	COG0747	negative chemotaxis
AXK16_RS00985	COG3479	Phenolic acid decarboxylase
AXK16_RS01030	COG0477	Major facilitator Superfamily
AXK16_RS01040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AXK16_RS01055	COG3714	YhhN family
AXK16_RS01065	COG3776	membrane
AXK16_RS01070	COG0742	ribosomal rna small subunit methyltransferase
AXK16_RS01075	COG0552	protein localization to endoplasmic reticulum
AXK16_RS01080	COG2884	Cell division ATP-binding protein ftsE
AXK16_RS01085	COG2177	Part of the ABC transporter FtsEX involved in
AXK16_RS01100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXK16_RS01110	COG0683	leucine binding
AXK16_RS01120	COG0683	leucine binding
AXK16_RS01125	COG0559	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS01175	COG0584	glycerophosphoryl diester phosphodiesterase
AXK16_RS01185	COG0405	Gamma-glutamyltransferase
AXK16_RS01190	COG1247	-acetyltransferase
AXK16_RS01205	COG0673	inositol 2-dehydrogenase activity
AXK16_RS01210	COG1741	Belongs to the pirin family
AXK16_RS01215	COG1609	Transcriptional regulator
AXK16_RS01220	COG3265	gluconokinase activity
AXK16_RS01225	COG2610	gluconate transmembrane transporter activity
AXK16_RS01235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXK16_RS01260	COG0058	SHG alpha-glucan phosphorylase activity
AXK16_RS01275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AXK16_RS01290	COG1349	DNA-binding transcription factor activity
AXK16_RS01305	COG0058	SHG alpha-glucan phosphorylase activity
AXK16_RS01310	COG1640	4-alpha-glucanotransferase
AXK16_RS01315	COG2610	gluconate transmembrane transporter activity
AXK16_RS01325	COG1040	competence protein
AXK16_RS01350	COG1918	ferrous iron import across plasma membrane
AXK16_RS01355	COG2183	response to ionizing radiation
AXK16_RS01360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXK16_RS01385	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AXK16_RS01390	COG1011	Hydrolase
AXK16_RS01400	COG0494	nUDIX hydrolase
AXK16_RS01405	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AXK16_RS01430	COG4796	Type ii and iii secretion system protein
AXK16_RS01450	COG3266	domain, Protein
AXK16_RS01455	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AXK16_RS01460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AXK16_RS01485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXK16_RS01490	COG0402	S-adenosylhomocysteine deaminase activity
AXK16_RS01495	COG0738	Major facilitator superfamily
AXK16_RS01520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXK16_RS01540	COG1765	OsmC-like protein
AXK16_RS01545	COG3954	Phosphoribulokinase
AXK16_RS01555	COG0429	hydrolase of the alpha beta-hydrolase fold
AXK16_RS01565	COG0488	(ABC) transporter
AXK16_RS01580	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AXK16_RS01585	COG1047	Peptidyl-prolyl cis-trans
AXK16_RS01595	COG0545	Peptidyl-prolyl cis-trans isomerase
AXK16_RS01600	COG2964	Protein conserved in bacteria
AXK16_RS01655	COG0051	transcription antitermination factor activity, RNA binding
AXK16_RS01680	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AXK16_RS01695	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AXK16_RS01760	COG0201	protein transport
AXK16_RS01785	COG0202	RNA polymerase activity
AXK16_RS01800	COG0789	Transcriptional regulator
AXK16_RS01805	COG3036	rescue of stalled ribosome
AXK16_RS01835	COG0758	DNA mediated transformation
AXK16_RS01845	COG0551	DNA topoisomerase type I activity
AXK16_RS01865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AXK16_RS01900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXK16_RS01905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK16_RS01910	COG1309	transcriptional regulator
AXK16_RS01915	COG0582	viral genome integration into host DNA
AXK16_RS01930	COG3561	AntA/AntB antirepressor
AXK16_RS02020	COG4626	Terminase
AXK16_RS02020	COG1802	Transcriptional regulator
AXK16_RS02050	COG4145	pantothenate transmembrane transporter activity
AXK16_RS02055	COG3924	membrane
AXK16_RS02060	COG0439	Biotin carboxylase
AXK16_RS02065	COG0511	ligase activity, forming carbon-carbon bonds
AXK16_RS02095	COG2199	diguanylate cyclase activity
AXK16_RS02095	COG2200	EAL domain
AXK16_RS02105	COG1077	Cell shape determining protein MreB Mrl
AXK16_RS02110	COG1792	Involved in formation and maintenance of cell shape
AXK16_RS02115	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AXK16_RS02125	COG1530	ribonuclease E activity
AXK16_RS02130	COG3164	Protein of unknown function
AXK16_RS02135	COG0312	modulator of DNA gyrase
AXK16_RS02140	COG0583	DNA-binding transcription factor activity
AXK16_RS02155	COG1289	transmembrane transporter activity
AXK16_RS02160	COG2732	(Barnase) inhibitor
AXK16_RS02185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXK16_RS02190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXK16_RS02195	COG3105	Protein conserved in bacteria
AXK16_RS02200	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AXK16_RS02220	COG0625	glutathione transferase activity
AXK16_RS02225	COG2969	positive regulation of protein catabolic process
AXK16_RS02235	COG0493	'glutamate synthase
AXK16_RS02245	COG1242	4 iron, 4 sulfur cluster binding
AXK16_RS02250	COG2271	Major facilitator Superfamily
AXK16_RS02255	COG1063	alcohol dehydrogenase
AXK16_RS02260	COG1312	Catalyzes the dehydration of D-mannonate
AXK16_RS02265	COG0784	Response regulator, receiver
AXK16_RS02265	COG2198	Histidine kinase
AXK16_RS02265	COG5002	protein histidine kinase activity
AXK16_RS02270	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AXK16_RS02280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS02290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS02295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AXK16_RS02300	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AXK16_RS02305	COG1137	ATPase activity
AXK16_RS02310	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AXK16_RS02315	COG3117	lipopolysaccharide transmembrane transporter activity
AXK16_RS02320	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AXK16_RS02330	COG0530	calcium, potassium:sodium antiporter activity
AXK16_RS02340	COG1127	ABC transporter
AXK16_RS02345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AXK16_RS02350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AXK16_RS02355	COG2854	intermembrane phospholipid transfer
AXK16_RS02360	COG3113	response to antibiotic
AXK16_RS02365	COG5007	Belongs to the BolA IbaG family
AXK16_RS02375	COG3423	Transcriptional regulator
AXK16_RS02380	COG0142	geranyltranstransferase activity
AXK16_RS02395	COG0697	spore germination
AXK16_RS02405	COG2027	D-alanyl-D-alanine carboxypeptidase
AXK16_RS02415	COG1534	Rna-binding protein
AXK16_RS02430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXK16_RS02435	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AXK16_RS02445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AXK16_RS02525	COG0814	amino acid
AXK16_RS02535	COG0826	peptidase U32
AXK16_RS02540	COG0826	peptidase U32
AXK16_RS02545	COG3154	lipid carrier protein
AXK16_RS02550	COG3153	acetyltransferase
AXK16_RS02565	COG0693	protein deglycase activity
AXK16_RS02570	COG0702	epimerase
AXK16_RS02580	COG2823	Periplasmic or secreted lipoprotein
AXK16_RS02600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AXK16_RS02615	COG1063	alcohol dehydrogenase
AXK16_RS02620	COG3775	system Galactitol-specific IIC component
AXK16_RS02625	COG3414	Phosphotransferase system galactitol-specific IIB component
AXK16_RS02630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS02640	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS02640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS02645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS02645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXK16_RS02645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXK16_RS02650	COG1105	Belongs to the carbohydrate kinase PfkB family
AXK16_RS02660	COG1349	DNA-binding transcription factor activity
AXK16_RS02665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXK16_RS02670	COG2721	sulfolactate sulfo-lyase activity
AXK16_RS02675	COG2271	Major facilitator Superfamily
AXK16_RS02685	COG2084	Dehydrogenase
AXK16_RS02690	COG1929	Belongs to the glycerate kinase type-1 family
AXK16_RS02710	COG1741	Belongs to the pirin family
AXK16_RS02715	COG0583	DNA-binding transcription factor activity
AXK16_RS02720	COG3152	Membrane
AXK16_RS02725	COG0435	Glutathione S-transferase
AXK16_RS02730	COG2259	Doxx family
AXK16_RS02740	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AXK16_RS02745	COG4575	ribosome binding
AXK16_RS02750	COG1422	Protein of unknown function (DUF1090)
AXK16_RS02760	COG0586	Pfam SNARE associated Golgi protein
AXK16_RS02765	COG2186	Transcriptional regulator
AXK16_RS02770	COG2271	Major facilitator Superfamily
AXK16_RS02780	COG2721	sulfolactate sulfo-lyase activity
AXK16_RS02795	COG0861	Integral membrane protein TerC family
AXK16_RS02800	COG0673	inositol 2-dehydrogenase activity
AXK16_RS02805	COG1451	nucleotide metabolic process
AXK16_RS02825	COG1902	pentaerythritol trinitrate reductase activity
AXK16_RS02825	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXK16_RS02880	COG1695	Transcriptional regulator
AXK16_RS02900	COG1461	Dihydroxyacetone kinase
AXK16_RS02905	COG2376	Dihydroxyacetone kinase
AXK16_RS02985	COG3247	response to pH
AXK16_RS02995	COG0784	Response regulator, receiver
AXK16_RS02995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK16_RS02995	COG2198	Histidine kinase
AXK16_RS02995	COG2205	protein histidine kinase activity
AXK16_RS03000	COG2197	response regulator
AXK16_RS03015	COG4974	Belongs to the 'phage' integrase family
AXK16_RS03090	COG4695	Portal protein
AXK16_RS03250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXK16_RS03255	COG0358	DNA primase activity
AXK16_RS03260	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AXK16_RS03325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AXK16_RS03340	COG4991	sh3 domain protein
AXK16_RS03345	COG3025	triphosphatase activity
AXK16_RS03365	COG2960	long-chain fatty acid transporting porin activity
AXK16_RS03380	COG3384	dioxygenase
AXK16_RS03385	COG0754	glutathionylspermidine amidase activity
AXK16_RS03405	COG3151	Protein conserved in bacteria
AXK16_RS03410	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXK16_RS03415	COG3150	esterase
AXK16_RS03425	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AXK16_RS03430	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXK16_RS03435	COG0642	Histidine kinase
AXK16_RS03445	COG3111	PFAM Bacterial OB fold (BOF) protein
AXK16_RS03450	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AXK16_RS03455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXK16_RS03460	COG0204	Acyl-transferase
AXK16_RS03470	COG1032	radical SAM domain protein
AXK16_RS03480	COG0656	L-ascorbic acid biosynthetic process
AXK16_RS03485	COG1979	alcohol dehydrogenase
AXK16_RS03490	COG2207	Transcriptional regulator
AXK16_RS03495	COG0586	Pfam SNARE associated Golgi protein
AXK16_RS03500	COG0626	cystathionine gamma-synthase activity
AXK16_RS03515	COG0848	biopolymer transport protein
AXK16_RS03520	COG2211	Major facilitator Superfamily
AXK16_RS03545	COG0625	glutathione transferase activity
AXK16_RS03580	COG0583	DNA-binding transcription factor activity
AXK16_RS03585	COG0626	cystathionine gamma-synthase activity
AXK16_RS03855	COG1278	Cold shock
AXK16_RS03860	COG3423	Transcriptional regulator
AXK16_RS03920	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AXK16_RS03930	COG1811	Na channel or pump
AXK16_RS03940	COG1982	Orn Lys Arg decarboxylase major
AXK16_RS03945	COG2211	Major facilitator Superfamily
AXK16_RS03960	COG1194	a g-specific adenine glycosylase
AXK16_RS03970	COG3171	Protein conserved in bacteria
AXK16_RS03980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXK16_RS03995	COG0762	integral membrane protein
AXK16_RS04000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AXK16_RS04005	COG2805	Type II/IV secretion system protein
AXK16_RS04025	COG0189	ligase activity
AXK16_RS04030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AXK16_RS04035	COG2356	endonuclease I
AXK16_RS04045	COG2814	Major facilitator Superfamily
AXK16_RS04080	COG2146	nitrite reductase [NAD(P)H] activity
AXK16_RS04095	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS04100	COG1414	Transcriptional regulator
AXK16_RS04130	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS04135	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AXK16_RS04155	COG0501	Belongs to the peptidase M48B family
AXK16_RS04160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AXK16_RS04175	COG0191	fructose-bisphosphate aldolase activity
AXK16_RS04180	COG0668	transmembrane transport
AXK16_RS04190	COG2968	Membrane
AXK16_RS04205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXK16_RS04210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AXK16_RS04230	COG0006	proline dipeptidase activity
AXK16_RS04235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXK16_RS04240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXK16_RS04260	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS04265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXK16_RS04290	COG1737	Transcriptional regulator
AXK16_RS04300	COG1272	protein, Hemolysin III
AXK16_RS04310	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AXK16_RS04320	COG0716	FMN binding
AXK16_RS04325	COG4974	Belongs to the 'phage' integrase family
AXK16_RS04335	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AXK16_RS04360	COG4942	peptidase
AXK16_RS04370	COG2814	Major facilitator Superfamily
AXK16_RS04385	COG0667	Aldo Keto reductase
AXK16_RS04420	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AXK16_RS04425	COG1393	Belongs to the ArsC family
AXK16_RS04440	COG1538	Outer membrane efflux protein
AXK16_RS04445	COG1289	transmembrane transporter activity
AXK16_RS04460	COG3592	Divergent 4Fe-4S mono-cluster
AXK16_RS04465	COG2388	GCN5-related N-acetyl-transferase
AXK16_RS04475	COG3539	Fimbrial protein
AXK16_RS04480	COG3539	Fimbrial protein
AXK16_RS04485	COG3539	Fimbrial protein
AXK16_RS04490	COG3188	usher protein
AXK16_RS04495	COG3121	Chaperone
AXK16_RS04500	COG3539	Fimbrial protein
AXK16_RS04510	COG4974	Belongs to the 'phage' integrase family
AXK16_RS04530	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AXK16_RS04535	COG1846	Transcriptional regulator
AXK16_RS04540	COG0697	spore germination
AXK16_RS04590	COG0667	Aldo Keto reductase
AXK16_RS04595	COG0814	amino acid
AXK16_RS04610	COG0183	Belongs to the thiolase family
AXK16_RS04625	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS04630	COG2814	Major facilitator Superfamily
AXK16_RS04665	COG0395	ABC-type sugar transport system, permease component
AXK16_RS04670	COG1175	transmembrane transport
AXK16_RS04675	COG1917	Cupin 2, conserved barrel domain protein
AXK16_RS04680	COG1794	racemase activity, acting on amino acids and derivatives
AXK16_RS04685	COG0583	DNA-binding transcription factor activity
AXK16_RS04695	COG1609	Transcriptional regulator
AXK16_RS04700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXK16_RS04705	COG2723	6-phospho-beta-galactosidase activity
AXK16_RS04710	COG2186	Transcriptional regulator
AXK16_RS04720	COG1609	Transcriptional regulator
AXK16_RS04745	COG0667	Aldo Keto reductase
AXK16_RS04755	COG0861	Integral membrane protein TerC family
AXK16_RS04785	COG2165	general secretion pathway protein
AXK16_RS04790	COG4795	General secretion pathway protein
AXK16_RS04800	COG4967	type IV pilus modification protein PilV
AXK16_RS04805	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AXK16_RS04830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AXK16_RS04830	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AXK16_RS04840	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AXK16_RS04870	COG4656	Part of a membrane complex involved in electron transport
AXK16_RS04875	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS04875	COG1454	alcohol dehydrogenase
AXK16_RS04905	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AXK16_RS05070	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AXK16_RS05075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AXK16_RS05080	COG2166	iron-sulfur cluster assembly
AXK16_RS05095	COG0583	DNA-binding transcription factor activity
AXK16_RS05100	COG2363	Small membrane protein
AXK16_RS05110	COG1349	DNA-binding transcription factor activity
AXK16_RS05130	COG0738	Major facilitator superfamily
AXK16_RS05135	COG0235	Class ii aldolase
AXK16_RS05140	COG1454	alcohol dehydrogenase
AXK16_RS05155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXK16_RS05170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXK16_RS05180	COG1464	Belongs to the NlpA lipoprotein family
AXK16_RS05190	COG0477	Major facilitator Superfamily
AXK16_RS05200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXK16_RS05205	COG1760	l-serine dehydratase
AXK16_RS05215	COG1611	Belongs to the LOG family
AXK16_RS05230	COG3098	single-species biofilm formation
AXK16_RS05235	COG0564	pseudouridine synthase activity
AXK16_RS05240	COG0716	FMN binding
AXK16_RS05245	COG2271	Major facilitator Superfamily
AXK16_RS05250	COG4948	Mandelate Racemase Muconate Lactonizing
AXK16_RS05255	COG4948	Mandelate Racemase Muconate Lactonizing
AXK16_RS05265	COG3850	Histidine kinase
AXK16_RS05265	COG2205	protein histidine kinase activity
AXK16_RS05265	COG3437	response regulator, receiver
AXK16_RS05265	COG4999	Histidine kinase
AXK16_RS05275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXK16_RS05280	COG3956	TIGRFAM MazG family protein
AXK16_RS05300	COG0602	queuosine metabolic process
AXK16_RS05305	COG0720	synthase
AXK16_RS05325	COG2234	aminopeptidase activity
AXK16_RS05385	COG1388	LysM domain
AXK16_RS05385	COG4942	peptidase
AXK16_RS05390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXK16_RS05415	COG0163	prenyltransferase activity
AXK16_RS05420	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AXK16_RS05460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXK16_RS05465	COG4558	Periplasmic binding protein
AXK16_RS05470	COG3720	iron ion transport
AXK16_RS05490	COG0679	Auxin Efflux Carrier
AXK16_RS05505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXK16_RS05510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXK16_RS05515	COG1121	(ABC) transporter
AXK16_RS05520	COG0803	Belongs to the bacterial solute-binding protein 9 family
AXK16_RS05525	COG1609	Transcriptional regulator
AXK16_RS05530	COG1940	carbohydrate kinase activity
AXK16_RS05535	COG1447	Phosphotransferase system cellobiose-specific component IIA
AXK16_RS05540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXK16_RS05545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXK16_RS05555	COG4580	involved in the transport of maltose and maltodextrins
AXK16_RS05565	COG2723	6-phospho-beta-galactosidase activity
AXK16_RS05575	COG0309	Hydrogenase expression formation protein (HypE)
AXK16_RS05580	COG0409	Hydrogenase expression formation protein
AXK16_RS05585	COG0298	carbon dioxide binding
AXK16_RS05590	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AXK16_RS05610	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXK16_RS05615	COG0651	ATP synthesis coupled electron transport
AXK16_RS05620	COG0650	Formate hydrogenlyase subunit 4
AXK16_RS05625	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AXK16_RS05625	COG3261	NADH dehydrogenase
AXK16_RS05630	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXK16_RS05635	COG3260	NADH ubiquinone oxidoreductase 20
AXK16_RS05645	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AXK16_RS05655	COG2723	6-phospho-beta-galactosidase activity
AXK16_RS05660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXK16_RS05660	COG1263	PTS System
AXK16_RS05665	COG1609	Transcriptional regulator
AXK16_RS05670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXK16_RS05675	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AXK16_RS05680	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AXK16_RS05710	COG1349	DNA-binding transcription factor activity
AXK16_RS05715	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS05720	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS05730	COG3732	PTS system glucitol sorbitol-specific
AXK16_RS05735	COG3730	PTS system glucitol sorbitol-specific
AXK16_RS05740	COG2951	lytic endotransglycosylase activity
AXK16_RS05745	COG1121	(ABC) transporter
AXK16_RS05750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXK16_RS05760	COG1546	Belongs to the CinA family
AXK16_RS05785	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AXK16_RS05815	COG2823	Periplasmic or secreted lipoprotein
AXK16_RS05820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXK16_RS05825	COG1238	metal cluster binding
AXK16_RS05845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXK16_RS05850	COG2814	Major facilitator Superfamily
AXK16_RS05860	COG1846	Transcriptional regulator
AXK16_RS05870	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AXK16_RS05880	COG4176	ABC-type proline glycine betaine transport system permease component
AXK16_RS05895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXK16_RS05905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXK16_RS05910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXK16_RS05915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXK16_RS05920	COG4575	ribosome binding
AXK16_RS05940	COG2916	Histone family protein nucleoid-structuring protein H-NS
AXK16_RS05955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXK16_RS05960	COG0640	Transcriptional regulator
AXK16_RS05970	COG0583	DNA-binding transcription factor activity
AXK16_RS05975	COG3284	Transcriptional regulator
AXK16_RS05985	COG3539	Fimbrial protein
AXK16_RS05990	COG3121	Chaperone
AXK16_RS06010	COG3188	usher protein
AXK16_RS06020	COG3539	Fimbrial protein
AXK16_RS06025	COG2197	response regulator
AXK16_RS06040	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS06050	COG0235	Class ii aldolase
AXK16_RS06060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK16_RS06095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK16_RS06100	COG2207	Transcriptional regulator
AXK16_RS06100	COG3708	Transcriptional regulator
AXK16_RS06125	COG4974	Belongs to the 'phage' integrase family
AXK16_RS06160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AXK16_RS06180	COG3344	reverse transcriptase
AXK16_RS06225	COG4695	Portal protein
AXK16_RS06385	COG2867	negative regulation of translational initiation
AXK16_RS06400	COG0497	DNA recombination
AXK16_RS06420	COG4536	flavin adenine dinucleotide binding
AXK16_RS06425	COG4137	Cytochrome C assembly protein
AXK16_RS06430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AXK16_RS06465	COG2885	chlorophyll binding
AXK16_RS06470	COG2199	diguanylate cyclase activity
AXK16_RS06480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXK16_RS06485	COG1605	Chorismate mutase
AXK16_RS06485	COG0287	Prephenate dehydrogenase
AXK16_RS06495	COG1605	Chorismate mutase
AXK16_RS06495	COG0077	Prephenate dehydratase
AXK16_RS06500	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AXK16_RS06505	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXK16_RS06510	COG0564	pseudouridine synthase activity
AXK16_RS06525	COG0542	response to heat
AXK16_RS06550	COG0477	Major facilitator Superfamily
AXK16_RS06555	COG5544	Lipoprotein
AXK16_RS06560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXK16_RS06570	COG3148	PFAM DTW domain containing protein
AXK16_RS06575	COG3118	belongs to the thioredoxin family
AXK16_RS06580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXK16_RS06595	COG0513	Belongs to the DEAD box helicase family
AXK16_RS06605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AXK16_RS06615	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AXK16_RS06620	COG3026	antisigma factor binding
AXK16_RS06625	COG3086	response to oxidative stress
AXK16_RS06635	COG0681	Belongs to the peptidase S26 family
AXK16_RS06655	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AXK16_RS06665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXK16_RS06670	COG1737	Transcriptional regulator
AXK16_RS06675	COG0560	Phosphoserine phosphatase
AXK16_RS06690	COG0047	phosphoribosylformylglycinamidine synthase activity
AXK16_RS06690	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXK16_RS06695	COG2205	protein histidine kinase activity
AXK16_RS06705	COG2204	response regulator
AXK16_RS06710	COG0347	Belongs to the P(II) protein family
AXK16_RS06715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXK16_RS06715	COG1017	nitric oxide dioxygenase activity
AXK16_RS06730	COG2259	Doxx family
AXK16_RS06735	COG1940	carbohydrate kinase activity
AXK16_RS06740	COG0457	Tetratricopeptide repeat
AXK16_RS06745	COG2814	Major facilitator Superfamily
AXK16_RS06745	COG0477	Major facilitator Superfamily
AXK16_RS06750	COG2017	converts alpha-aldose to the beta-anomer
AXK16_RS06755	COG2814	Major facilitator Superfamily
AXK16_RS06760	COG3711	transcriptional antiterminator
AXK16_RS06765	COG3683	transport system, periplasmic component
AXK16_RS06770	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AXK16_RS06800	COG0822	iron-sulfur transferase activity
AXK16_RS06820	COG0633	Ferredoxin
AXK16_RS06845	COG2897	thiosulfate sulfurtransferase activity
AXK16_RS06850	COG2373	Large extracellular alpha-helical protein
AXK16_RS06855	COG4953	penicillin-binding protein 1C
AXK16_RS06885	COG2976	Protein conserved in bacteria
AXK16_RS06905	COG1645	bacterial-type flagellum-dependent swarming motility
AXK16_RS06915	COG0516	GMP reductase activity
AXK16_RS06915	COG0517	IMP dehydrogenase activity
AXK16_RS06925	COG3119	arylsulfatase activity
AXK16_RS06950	COG2200	EAL domain
AXK16_RS06965	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AXK16_RS06980	COG2723	6-phospho-beta-galactosidase activity
AXK16_RS06995	COG2233	PERMEase
AXK16_RS07010	COG1393	Belongs to the ArsC family
AXK16_RS07015	COG4783	chaperone-mediated protein folding
AXK16_RS07020	COG0628	permease
AXK16_RS07025	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AXK16_RS07030	COG2716	regulation of RNA biosynthetic process
AXK16_RS07040	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AXK16_RS07050	COG2321	neutral zinc metallopeptidase
AXK16_RS07055	COG1444	tRNA N-acetyltransferase activity
AXK16_RS07060	COG0400	carboxylic ester hydrolase activity
AXK16_RS07075	COG1393	Belongs to the ArsC family
AXK16_RS07080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXK16_RS07100	COG5342	invasion associated locus B
AXK16_RS07105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AXK16_RS07110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AXK16_RS07120	COG4810	utilization protein
AXK16_RS07210	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXK16_RS07230	COG2837	iron assimilation
AXK16_RS07240	COG4150	thiosulfate binding
AXK16_RS07245	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AXK16_RS07250	COG4208	sulfate ABC transporter
AXK16_RS07255	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AXK16_RS07265	COG4319	ketosteroid isomerase
AXK16_RS07300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AXK16_RS07320	COG3530	Putative quorum-sensing-regulated virulence factor
AXK16_RS07325	COG0385	Bile acid
AXK16_RS07330	COG0583	DNA-binding transcription factor activity
AXK16_RS07360	COG3415	Transposase
AXK16_RS07365	COG3415	Transposase
AXK16_RS07380	COG2199	diguanylate cyclase activity
AXK16_RS07380	COG2200	EAL domain
AXK16_RS07385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXK16_RS07400	COG0667	Aldo Keto reductase
AXK16_RS07405	COG3961	Belongs to the TPP enzyme family
AXK16_RS07420	COG3279	Response regulator of the LytR AlgR family
AXK16_RS07435	COG0436	Aminotransferase
AXK16_RS07440	COG2807	transmembrane transport
AXK16_RS07445	COG0590	tRNA wobble adenosine to inosine editing
AXK16_RS07450	COG0583	DNA-binding transcription factor activity
AXK16_RS07470	COG2116	formate transmembrane transporter activity
AXK16_RS07475	COG2853	Lipoprotein
AXK16_RS07485	COG3691	Protein conserved in bacteria
AXK16_RS07500	COG2062	phosphohistidine phosphatase, SixA
AXK16_RS07525	COG0730	response to heat
AXK16_RS07530	COG3101	peptidyl-lysine hydroxylation
AXK16_RS07545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXK16_RS07565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXK16_RS07575	COG0586	Pfam SNARE associated Golgi protein
AXK16_RS07585	COG0285	dihydrofolate synthase activity
AXK16_RS07590	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AXK16_RS07595	COG1286	toxin biosynthetic process
AXK16_RS07600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AXK16_RS07605	COG0163	prenyltransferase activity
AXK16_RS07625	COG4160	amino acid transport
AXK16_RS07630	COG4598	ABC transporter
AXK16_RS07640	COG1090	epimerase
AXK16_RS07645	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AXK16_RS07650	COG0625	glutathione transferase activity
AXK16_RS07655	COG0625	glutathione transferase activity
AXK16_RS07660	COG0622	Phosphoesterase
AXK16_RS07665	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AXK16_RS07670	COG0857	belongs to the CobB CobQ family
AXK16_RS07670	COG0280	phosphate acetyltransferase
AXK16_RS07690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXK16_RS07695	COG0471	metal ion transport
AXK16_RS07695	COG0490	domain, Protein
AXK16_RS07705	COG0436	Aminotransferase
AXK16_RS07710	COG0583	DNA-binding transcription factor activity
AXK16_RS07760	COG0839	Belongs to the complex I subunit 6 family
AXK16_RS07770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AXK16_RS07775	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXK16_RS07790	COG2153	protein acetylation
AXK16_RS07795	COG1169	isochorismate synthase
AXK16_RS07820	COG0318	PFAM AMP-dependent synthetase and ligase
AXK16_RS07830	COG5464	transposase or invertase
AXK16_RS07845	COG1414	Transcriptional regulator
AXK16_RS07855	COG2271	Major facilitator Superfamily
AXK16_RS07865	COG0247	lactate metabolic process
AXK16_RS07875	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AXK16_RS07880	COG2271	Major facilitator Superfamily
AXK16_RS07885	COG0584	glycerophosphoryl diester phosphodiesterase
AXK16_RS07895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXK16_RS07935	COG2198	Histidine kinase
AXK16_RS07935	COG0642	Histidine kinase
AXK16_RS07950	COG2169	Transcriptional regulator
AXK16_RS07950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXK16_RS07955	COG3145	DNA-N1-methyladenine dioxygenase activity
AXK16_RS07960	COG4615	Cyclic peptide transporter
AXK16_RS07965	COG2239	Acts as a magnesium transporter
AXK16_RS07970	COG0659	secondary active sulfate transmembrane transporter activity
AXK16_RS08010	COG1349	DNA-binding transcription factor activity
AXK16_RS08015	COG0494	nUDIX hydrolase
AXK16_RS08035	COG1061	Type III restriction enzyme res subunit
AXK16_RS08040	COG1187	pseudouridine synthase activity
AXK16_RS08045	COG2814	Major facilitator Superfamily
AXK16_RS08055	COG4172	Belongs to the ABC transporter superfamily
AXK16_RS08060	COG4239	(ABC) transporter, permease
AXK16_RS08065	COG4174	ABC transporter (Permease)
AXK16_RS08070	COG4166	transmembrane transport
AXK16_RS08075	COG2200	EAL domain
AXK16_RS08080	COG0791	NLP P60 protein
AXK16_RS08085	COG0671	phosphoesterase, PA-phosphatase related
AXK16_RS08090	COG0523	cobalamin synthesis protein
AXK16_RS08095	COG0246	Mannitol dehydrogenase
AXK16_RS08100	COG1312	Catalyzes the dehydration of D-mannonate
AXK16_RS08125	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS08125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS08130	COG1105	Belongs to the carbohydrate kinase PfkB family
AXK16_RS08135	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AXK16_RS08135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXK16_RS08135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXK16_RS08140	COG3344	reverse transcriptase
AXK16_RS08150	COG2855	membrane
AXK16_RS08160	COG0583	DNA-binding transcription factor activity
AXK16_RS08165	COG0833	amino acid
AXK16_RS08175	COG2801	Transposase and inactivated derivatives
AXK16_RS08185	COG4771	TonB-dependent receptor
AXK16_RS08200	COG2311	Membrane
AXK16_RS08220	COG1129	ABC transporter
AXK16_RS08230	COG2949	membrane
AXK16_RS08245	COG1346	cytolysis
AXK16_RS08260	COG3659	wide pore channel activity
AXK16_RS08275	COG2723	6-phospho-beta-galactosidase activity
AXK16_RS08280	COG1538	Outer membrane efflux protein
AXK16_RS08285	COG0586	Pfam SNARE associated Golgi protein
AXK16_RS08295	COG1686	Belongs to the peptidase S11 family
AXK16_RS08305	COG0277	FAD linked oxidase domain protein
AXK16_RS08310	COG1472	Belongs to the glycosyl hydrolase 3 family
AXK16_RS08315	COG1732	Glycine betaine
AXK16_RS08320	COG1174	glycine betaine transport
AXK16_RS08325	COG1125	glycine betaine transport
AXK16_RS08330	COG1174	glycine betaine transport
AXK16_RS08340	COG3275	phosphorelay sensor kinase activity
AXK16_RS08350	COG4807	Protein conserved in bacteria
AXK16_RS08370	COG5455	response to cobalt ion
AXK16_RS08375	COG0583	DNA-binding transcription factor activity
AXK16_RS08380	COG2252	PERMEase
AXK16_RS08390	COG0583	DNA-binding transcription factor activity
AXK16_RS08405	COG0351	phosphomethylpyrimidine kinase
AXK16_RS08410	COG1830	Aldolase
AXK16_RS08420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AXK16_RS08445	COG1070	Carbohydrate kinase
AXK16_RS08455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXK16_RS08465	COG0747	negative chemotaxis
AXK16_RS08470	COG0601	transmembrane transport
AXK16_RS08475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXK16_RS08480	COG0444	Belongs to the ABC transporter superfamily
AXK16_RS08485	COG4608	Belongs to the ABC transporter superfamily
AXK16_RS08495	COG0826	peptidase U32
AXK16_RS08500	COG0745	RESPONSE REGULATOR receiver
AXK16_RS08505	COG2205	protein histidine kinase activity
AXK16_RS08530	COG1301	dicarboxylic acid transport
AXK16_RS08545	COG5002	protein histidine kinase activity
AXK16_RS08550	COG0443	Heat shock 70 kDa protein
AXK16_RS08555	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AXK16_RS08570	COG2982	Protein involved in outer membrane biogenesis
AXK16_RS08575	COG1253	flavin adenine dinucleotide binding
AXK16_RS08625	COG1216	Glycosyl transferase, family 2
AXK16_RS08625	COG0463	Glycosyl transferase, family 2
AXK16_RS08650	COG2244	polysaccharide biosynthetic process
AXK16_RS08655	COG0463	Glycosyl transferase, family 2
AXK16_RS08670	COG1088	dTDP-glucose 4,6-dehydratase activity
AXK16_RS08725	COG0438	transferase activity, transferring glycosyl groups
AXK16_RS08730	COG1216	Glycosyl transferase, family 2
AXK16_RS08730	COG1442	glycosyl transferase family 8
AXK16_RS08765	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AXK16_RS08790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXK16_RS08795	COG0583	DNA-binding transcription factor activity
AXK16_RS08800	COG0531	amino acid
AXK16_RS08805	COG0640	Transcriptional regulator
AXK16_RS08815	COG2925	Exonuclease
AXK16_RS08835	COG1289	transmembrane transporter activity
AXK16_RS08855	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AXK16_RS08865	COG1942	4-Oxalocrotonate Tautomerase
AXK16_RS08870	COG0583	DNA-binding transcription factor activity
AXK16_RS08875	COG0095	Lipoate-protein ligase
AXK16_RS08880	COG0477	Major facilitator Superfamily
AXK16_RS08895	COG3300	MHYT domain
AXK16_RS08895	COG5001	Diguanylate cyclase
AXK16_RS08905	COG3615	Tellurite resistance protein tehB
AXK16_RS08930	COG3706	GGDEF domain
AXK16_RS08970	COG2963	transposase activity
AXK16_RS09110	COG4771	TonB-dependent receptor
AXK16_RS09115	COG1021	2,3-dihydroxybenzoate-AMP ligase
AXK16_RS09135	COG2226	methyltransferase
AXK16_RS09135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXK16_RS09135	COG3433	isochorismatase activity
AXK16_RS09150	COG1132	(ABC) transporter
AXK16_RS09155	COG2814	Major facilitator Superfamily
AXK16_RS09160	COG1169	isochorismate synthase
AXK16_RS09165	COG0582	viral genome integration into host DNA
AXK16_RS09175	COG0534	Mate efflux family protein
AXK16_RS09185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXK16_RS09205	COG0604	alcohol dehydrogenase
AXK16_RS09280	COG0270	DNA (cytosine-5-)-methyltransferase activity
AXK16_RS09285	COG3727	T/G mismatch-specific endonuclease activity
AXK16_RS09290	COG0697	spore germination
AXK16_RS09295	COG2354	Protein conserved in bacteria
AXK16_RS09325	COG0366	Alpha amylase catalytic
AXK16_RS09330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK16_RS09340	COG0765	amino acid transport
AXK16_RS09345	COG1126	abc transporter atp-binding protein
AXK16_RS09350	COG2197	response regulator
AXK16_RS09360	COG2197	response regulator
AXK16_RS09395	COG3318	Belongs to the UPF0149 family
AXK16_RS09395	COG3012	SEC-C Motif Domain Protein
AXK16_RS09400	COG0814	amino acid
AXK16_RS09410	COG1528	Iron-storage protein
AXK16_RS09445	COG1528	Iron-storage protein
AXK16_RS09455	COG1879	ABC-type sugar transport system periplasmic component
AXK16_RS09465	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS09490	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AXK16_RS09500	COG3102	Protein conserved in bacteria
AXK16_RS09520	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AXK16_RS09525	COG1801	Protein of unknown function DUF72
AXK16_RS09530	COG1335	isochorismatase
AXK16_RS09540	COG0494	nUDIX hydrolase
AXK16_RS09565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXK16_RS09575	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AXK16_RS09580	COG0739	heme binding
AXK16_RS09585	COG1560	Kdo2-lipid A biosynthetic process
AXK16_RS09595	COG1737	Transcriptional regulator
AXK16_RS09610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AXK16_RS09615	COG0129	dihydroxy-acid dehydratase activity
AXK16_RS09620	COG0800	Aldolase
AXK16_RS09630	COG3141	response to X-ray
AXK16_RS09635	COG2979	Protein of unknown function (DUF533)
AXK16_RS09645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXK16_RS09655	COG2372	response to copper ion
AXK16_RS09660	COG1276	copper resistance
AXK16_RS09705	COG2990	Protein conserved in bacteria
AXK16_RS09730	COG3008	intermembrane lipid transfer
AXK16_RS09735	COG2995	paraquat-inducible protein a
AXK16_RS09740	COG1956	GAF domain-containing protein
AXK16_RS09760	COG2814	Major facilitator Superfamily
AXK16_RS09765	COG1414	Transcriptional regulator
AXK16_RS09810	COG0768	penicillin binding
AXK16_RS09815	COG2226	methyltransferase
AXK16_RS09835	COG3716	PTS system mannose fructose sorbose family IID component
AXK16_RS09840	COG3715	PTS system
AXK16_RS09845	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS09845	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXK16_RS09850	COG1253	flavin adenine dinucleotide binding
AXK16_RS09855	COG2200	EAL domain
AXK16_RS09860	COG1760	l-serine dehydratase
AXK16_RS09880	COG0251	oxidation-reduction process
AXK16_RS09885	COG1199	ATP-dependent helicase activity
AXK16_RS09895	COG3065	identical protein binding
AXK16_RS09905	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AXK16_RS09915	COG2894	cell division
AXK16_RS09930	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXK16_RS09960	COG2719	SpoVR family
AXK16_RS09980	COG1619	proteins homologs of microcin C7 resistance protein MccF
AXK16_RS09990	COG4774	siderophore transport
AXK16_RS10000	COG2211	Major facilitator Superfamily
AXK16_RS10010	COG2308	Evidence 4 Homologs of previously reported genes of
AXK16_RS10050	COG0583	DNA-binding transcription factor activity
AXK16_RS10055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXK16_RS10070	COG1882	Formate acetyltransferase
AXK16_RS10100	COG0583	DNA-binding transcription factor activity
AXK16_RS10130	COG0583	DNA-binding transcription factor activity
AXK16_RS10240	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXK16_RS10330	COG0012	GTP binding
AXK16_RS10350	COG0659	secondary active sulfate transmembrane transporter activity
AXK16_RS10385	COG2890	protein-(glutamine-N5) methyltransferase activity
AXK16_RS10405	COG0387	Pfam Sodium calcium exchanger
AXK16_RS10410	COG4572	Cation transport regulator
AXK16_RS10415	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AXK16_RS10425	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AXK16_RS10430	COG3707	response regulator
AXK16_RS10435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXK16_RS10445	COG1116	anion transmembrane transporter activity
AXK16_RS10450	COG2146	nitrite reductase [NAD(P)H] activity
AXK16_RS10450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXK16_RS10455	COG0243	molybdopterin cofactor binding
AXK16_RS10460	COG4932	domain protein
AXK16_RS10465	COG2197	response regulator
AXK16_RS10470	COG3850	Histidine kinase
AXK16_RS10475	COG2223	nitrite transmembrane transporter activity
AXK16_RS10480	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AXK16_RS10485	COG1140	nitrate reductase beta subunit
AXK16_RS10490	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AXK16_RS10495	COG2181	nitrate reductase activity
AXK16_RS10505	COG1522	sequence-specific DNA binding
AXK16_RS10540	COG0788	formyltetrahydrofolate deformylase activity
AXK16_RS10555	COG0745	RESPONSE REGULATOR receiver
AXK16_RS10560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AXK16_RS10565	COG2916	Histone family protein nucleoid-structuring protein H-NS
AXK16_RS10570	COG1435	thymidine kinase activity
AXK16_RS10575	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS10575	COG1454	alcohol dehydrogenase
AXK16_RS10585	COG2095	MarC family integral membrane protein
AXK16_RS10590	COG4166	transmembrane transport
AXK16_RS10595	COG0601	transmembrane transport
AXK16_RS10600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXK16_RS10605	COG0444	Belongs to the ABC transporter superfamily
AXK16_RS10615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXK16_RS10640	COG2353	YceI-like domain
AXK16_RS10645	COG2350	Protein conserved in bacteria
AXK16_RS10665	COG1105	Belongs to the carbohydrate kinase PfkB family
AXK16_RS10670	COG3137	Salt-induced outer membrane protein
AXK16_RS10700	COG3344	reverse transcriptase
AXK16_RS10730	COG0583	DNA-binding transcription factor activity
AXK16_RS10750	COG0386	Belongs to the glutathione peroxidase family
AXK16_RS10760	COG0791	NLP P60 protein
AXK16_RS10770	COG4256	Hemin uptake protein
AXK16_RS10775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXK16_RS10785	COG0574	Belongs to the PEP-utilizing enzyme family
AXK16_RS10785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXK16_RS10795	COG0628	permease
AXK16_RS10800	COG0277	FAD linked oxidase domain protein
AXK16_RS10800	COG0247	lactate metabolic process
AXK16_RS10805	COG2050	protein possibly involved in aromatic compounds catabolism
AXK16_RS10810	COG2261	transglycosylase associated protein
AXK16_RS10840	COG1120	ATPase activity
AXK16_RS10845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXK16_RS10855	COG0583	DNA-binding transcription factor activity
AXK16_RS10880	COG1304	FMN binding
AXK16_RS10885	COG1309	transcriptional regulator
AXK16_RS10900	COG0316	Belongs to the HesB IscA family
AXK16_RS10905	COG0719	Fe-S assembly protein
AXK16_RS10910	COG0396	ATPase activity
AXK16_RS10915	COG0719	Fe-S assembly protein
AXK16_RS10930	COG1376	ErfK ybiS ycfS ynhG family protein
AXK16_RS10955	COG1309	transcriptional regulator
AXK16_RS10960	COG1082	Xylose isomerase domain protein TIM barrel
AXK16_RS10960	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AXK16_RS10965	COG2271	Major facilitator Superfamily
AXK16_RS10970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXK16_RS10980	COG1120	ATPase activity
AXK16_RS10985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXK16_RS10995	COG1414	Transcriptional regulator
AXK16_RS11030	COG2814	Major facilitator Superfamily
AXK16_RS11050	COG0583	DNA-binding transcription factor activity
AXK16_RS11055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXK16_RS11075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXK16_RS11080	COG1116	anion transmembrane transporter activity
AXK16_RS11085	COG4774	siderophore transport
AXK16_RS11090	COG1120	ATPase activity
AXK16_RS11095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXK16_RS11100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXK16_RS11120	COG0765	amino acid transport
AXK16_RS11125	COG1126	abc transporter atp-binding protein
AXK16_RS11155	COG1473	amidohydrolase
AXK16_RS11165	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AXK16_RS11180	COG1175	transmembrane transport
AXK16_RS11210	COG4133	protoheme IX ABC transporter activity
AXK16_RS11215	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXK16_RS11220	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXK16_RS11240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXK16_RS11245	COG4235	cytochrome complex assembly
AXK16_RS11245	COG3088	subunit of a heme lyase
AXK16_RS11275	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AXK16_RS11290	COG3850	Histidine kinase
AXK16_RS11290	COG5002	protein histidine kinase activity
AXK16_RS11295	COG0745	RESPONSE REGULATOR receiver
AXK16_RS11350	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS11360	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXK16_RS11370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXK16_RS11380	COG0583	DNA-binding transcription factor activity
AXK16_RS11395	COG0277	FAD linked oxidase domain protein
AXK16_RS11400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXK16_RS11425	COG0402	S-adenosylhomocysteine deaminase activity
AXK16_RS11470	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS11470	COG0604	alcohol dehydrogenase
AXK16_RS11470	COG3321	synthase
AXK16_RS11500	COG4608	Belongs to the ABC transporter superfamily
AXK16_RS11505	COG0444	Belongs to the ABC transporter superfamily
AXK16_RS11530	COG0346	lactoylglutathione lyase activity
AXK16_RS11535	COG1349	DNA-binding transcription factor activity
AXK16_RS11565	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AXK16_RS11615	COG0307	riboflavin synthase, alpha
AXK16_RS11620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXK16_RS11625	COG2814	Major facilitator Superfamily
AXK16_RS11655	COG0791	NLP P60 protein
AXK16_RS11660	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AXK16_RS11670	COG0346	lactoylglutathione lyase activity
AXK16_RS11675	COG1902	pentaerythritol trinitrate reductase activity
AXK16_RS11680	COG1309	transcriptional regulator
AXK16_RS11685	COG3313	Fe-S protein
AXK16_RS11690	COG4989	oxidoreductase activity
AXK16_RS11695	COG2032	superoxide dismutase activity
AXK16_RS11700	COG1289	transmembrane transporter activity
AXK16_RS11705	COG1566	PFAM secretion protein HlyD family protein
AXK16_RS11735	COG3895	Periplasmic Protein
AXK16_RS11750	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AXK16_RS11755	COG0625	glutathione transferase activity
AXK16_RS11770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AXK16_RS11780	COG4659	FMN binding
AXK16_RS11815	COG2723	6-phospho-beta-galactosidase activity
AXK16_RS11825	COG0673	inositol 2-dehydrogenase activity
AXK16_RS11835	COG2814	Major facilitator Superfamily
AXK16_RS11855	COG3038	cytochrome b561
AXK16_RS11875	COG0583	DNA-binding transcription factor activity
AXK16_RS11885	COG3485	protocatechuate 3,4-dioxygenase
AXK16_RS11890	COG5383	Protein conserved in bacteria
AXK16_RS11895	COG2272	Belongs to the type-B carboxylesterase lipase family
AXK16_RS11910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXK16_RS11915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AXK16_RS11920	COG1275	C4-dicarboxylate transporter malic acid transport protein
AXK16_RS11925	COG0500	methyltransferase
AXK16_RS11940	COG3708	Transcriptional regulator
AXK16_RS11940	COG2207	Transcriptional regulator
AXK16_RS11945	COG3135	benzoate transporter
AXK16_RS11950	COG1396	sequence-specific DNA binding
AXK16_RS11960	COG0826	peptidase U32
AXK16_RS11980	COG1294	oxidase, subunit
AXK16_RS11990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXK16_RS11995	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AXK16_RS12000	COG3842	ATPase activity
AXK16_RS12005	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXK16_RS12010	COG1177	transmembrane transport
AXK16_RS12015	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS12045	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS12050	COG0747	negative chemotaxis
AXK16_RS12060	COG3238	Protein conserved in bacteria
AXK16_RS12065	COG1247	-acetyltransferase
AXK16_RS12075	COG2130	NADP-dependent
AXK16_RS12090	COG3691	Protein conserved in bacteria
AXK16_RS12095	COG1228	amidohydrolase
AXK16_RS12100	COG4772	TonB-dependent receptor
AXK16_RS12125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AXK16_RS12145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK16_RS12155	COG0765	amino acid transport
AXK16_RS12160	COG1126	abc transporter atp-binding protein
AXK16_RS12170	COG0625	glutathione transferase activity
AXK16_RS12200	COG2211	Major facilitator Superfamily
AXK16_RS12215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXK16_RS12220	COG3842	ATPase activity
AXK16_RS12225	COG1840	ABC-type Fe3 transport system, periplasmic component
AXK16_RS12230	COG1178	ABC-type Fe3 transport system permease component
AXK16_RS12240	COG2181	nitrate reductase activity
AXK16_RS12245	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AXK16_RS12250	COG1140	nitrate reductase beta subunit
AXK16_RS12255	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AXK16_RS12275	COG1414	Transcriptional regulator
AXK16_RS12280	COG4948	Mandelate Racemase Muconate Lactonizing
AXK16_RS12285	COG4829	muconolactone delta-isomerase
AXK16_RS12290	COG3485	protocatechuate 3,4-dioxygenase
AXK16_RS12300	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AXK16_RS12320	COG0243	molybdopterin cofactor binding
AXK16_RS12320	COG3383	formate dehydrogenase (NAD+) activity
AXK16_RS12325	COG0243	molybdopterin cofactor binding
AXK16_RS12325	COG3383	formate dehydrogenase (NAD+) activity
AXK16_RS12330	COG0437	4 iron, 4 sulfur cluster binding
AXK16_RS12335	COG2864	formate dehydrogenase
AXK16_RS12350	COG2326	polyphosphate kinase activity
AXK16_RS12360	COG2814	Major facilitator Superfamily
AXK16_RS12370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXK16_RS12380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXK16_RS12390	COG0747	negative chemotaxis
AXK16_RS12395	COG1064	alcohol dehydrogenase
AXK16_RS12410	COG0488	(ABC) transporter
AXK16_RS12450	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS12455	COG3729	General stress protein
AXK16_RS12470	COG3685	Protein conserved in bacteria
AXK16_RS12480	COG0366	Alpha amylase catalytic
AXK16_RS12490	COG2323	membrane
AXK16_RS12500	COG3111	PFAM Bacterial OB fold (BOF) protein
AXK16_RS12505	COG1764	response to oxidative stress
AXK16_RS12530	COG3781	membrane
AXK16_RS12535	COG0243	molybdopterin cofactor binding
AXK16_RS12540	COG0583	DNA-binding transcription factor activity
AXK16_RS12545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXK16_RS12570	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXK16_RS12575	COG1447	Phosphotransferase system cellobiose-specific component IIA
AXK16_RS12580	COG2814	Major facilitator Superfamily
AXK16_RS12590	COG1285	pathogenesis
AXK16_RS12595	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AXK16_RS12605	COG0583	DNA-binding transcription factor activity
AXK16_RS12625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXK16_RS12625	COG0519	Catalyzes the synthesis of GMP from XMP
AXK16_RS12665	COG0596	Alpha beta hydrolase
AXK16_RS12675	COG2205	protein histidine kinase activity
AXK16_RS12690	COG0076	glutamate decarboxylase activity
AXK16_RS12695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXK16_RS12700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXK16_RS12710	COG1116	anion transmembrane transporter activity
AXK16_RS12715	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXK16_RS12725	COG0673	inositol 2-dehydrogenase activity
AXK16_RS12735	COG1609	Transcriptional regulator
AXK16_RS12745	COG0402	S-adenosylhomocysteine deaminase activity
AXK16_RS12750	COG1953	Uracil, thiamine, allantoin
AXK16_RS12785	COG0406	alpha-ribazole phosphatase activity
AXK16_RS12815	COG3039	Transposase
AXK16_RS12835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXK16_RS12900	COG0765	amino acid transport
AXK16_RS12910	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AXK16_RS12920	COG2070	2-Nitropropane dioxygenase
AXK16_RS12925	COG0583	DNA-binding transcription factor activity
AXK16_RS12945	COG0477	Major facilitator Superfamily
AXK16_RS12985	COG1609	Transcriptional regulator
AXK16_RS12990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS13000	COG3037	sugar-specific permease SgaT UlaA
AXK16_RS13005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AXK16_RS13015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXK16_RS13020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXK16_RS13020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXK16_RS13020	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AXK16_RS13035	COG0583	DNA-binding transcription factor activity
AXK16_RS13040	COG0583	DNA-binding transcription factor activity
AXK16_RS13045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXK16_RS13055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXK16_RS13070	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS13080	COG1609	Transcriptional regulator
AXK16_RS13110	COG1652	LysM domain
AXK16_RS13130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXK16_RS13130	COG0426	domain, Protein
AXK16_RS13160	COG0456	acetyltransferase
AXK16_RS13160	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AXK16_RS13170	COG0667	Aldo Keto reductase
AXK16_RS13175	COG0667	Aldo Keto reductase
AXK16_RS13200	COG4977	sequence-specific DNA binding
AXK16_RS13220	COG4977	sequence-specific DNA binding
AXK16_RS13225	COG1349	DNA-binding transcription factor activity
AXK16_RS13240	COG1349	DNA-binding transcription factor activity
AXK16_RS13245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AXK16_RS13250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXK16_RS13255	COG0738	Major facilitator superfamily
AXK16_RS13300	COG1929	Belongs to the glycerate kinase type-1 family
AXK16_RS13305	COG3835	regulator
AXK16_RS13325	COG2186	Transcriptional regulator
AXK16_RS13345	COG2814	Major facilitator Superfamily
AXK16_RS13350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS13350	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS13365	COG2819	hydrolase of the alpha beta superfamily
AXK16_RS13405	COG3188	usher protein
AXK16_RS13415	COG1649	PFAM Uncharacterised BCR, COG1649
AXK16_RS13420	COG3550	peptidyl-serine autophosphorylation
AXK16_RS13425	COG1396	sequence-specific DNA binding
AXK16_RS13430	COG2351	hydroxyisourate hydrolase activity
AXK16_RS13435	COG3195	allantoin biosynthetic process
AXK16_RS13435	COG3648	Uricase
AXK16_RS13440	COG2233	PERMEase
AXK16_RS13470	COG2207	Transcriptional regulator
AXK16_RS13485	COG4628	conserved protein (DUF2132)
AXK16_RS13505	COG2011	ABC-type metal ion transport system permease component
AXK16_RS13520	COG0477	Major facilitator Superfamily
AXK16_RS13595	COG2199	diguanylate cyclase activity
AXK16_RS13610	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS13615	COG0583	DNA-binding transcription factor activity
AXK16_RS13625	COG0039	L-malate dehydrogenase activity
AXK16_RS13630	COG1349	DNA-binding transcription factor activity
AXK16_RS13635	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AXK16_RS13640	COG3395	kinase activity
AXK16_RS13650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXK16_RS13665	COG2731	YhcH YjgK YiaL family protein
AXK16_RS13670	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS13695	COG4977	sequence-specific DNA binding
AXK16_RS13705	COG0697	spore germination
AXK16_RS13710	COG2814	Major facilitator Superfamily
AXK16_RS13720	COG0410	ABC transporter
AXK16_RS13725	COG1129	ABC transporter
AXK16_RS13740	COG0683	leucine binding
AXK16_RS13745	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AXK16_RS13780	COG2223	nitrite transmembrane transporter activity
AXK16_RS13785	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AXK16_RS13800	COG1349	DNA-binding transcription factor activity
AXK16_RS13805	COG2084	Dehydrogenase
AXK16_RS13810	COG3395	kinase activity
AXK16_RS13815	COG0235	Class ii aldolase
AXK16_RS13820	COG3622	Belongs to the hyi family
AXK16_RS13825	COG2610	gluconate transmembrane transporter activity
AXK16_RS13830	COG3708	Transcriptional regulator
AXK16_RS13830	COG2207	Transcriptional regulator
AXK16_RS13845	COG2200	EAL domain
AXK16_RS13850	COG1546	Belongs to the CinA family
AXK16_RS13855	COG0071	Belongs to the small heat shock protein (HSP20) family
AXK16_RS13870	COG2197	response regulator
AXK16_RS13875	COG2135	peptidase activity
AXK16_RS13880	COG2207	Transcriptional regulator
AXK16_RS13895	COG4221	oxidoreductase activity
AXK16_RS13900	COG1802	Transcriptional regulator
AXK16_RS13905	COG0589	response to stress
AXK16_RS13910	COG0246	Mannitol dehydrogenase
AXK16_RS13915	COG2271	Major facilitator Superfamily
AXK16_RS13930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXK16_RS13950	COG0437	4 iron, 4 sulfur cluster binding
AXK16_RS13955	COG3302	dmso reductase anchor subunit
AXK16_RS13970	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AXK16_RS13975	COG1940	carbohydrate kinase activity
AXK16_RS13980	COG0583	DNA-binding transcription factor activity
AXK16_RS13985	COG2814	Major facilitator Superfamily
AXK16_RS13990	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AXK16_RS14000	COG3591	Belongs to the peptidase S1B family
AXK16_RS14025	COG0628	permease
AXK16_RS14055	COG0679	Auxin Efflux Carrier
AXK16_RS14090	COG3290	protein histidine kinase activity
AXK16_RS14095	COG4565	transcriptional regulatory protein
AXK16_RS14120	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AXK16_RS14120	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AXK16_RS14140	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXK16_RS14145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXK16_RS14155	COG0183	Belongs to the thiolase family
AXK16_RS14160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXK16_RS14170	COG1414	Transcriptional regulator
AXK16_RS14175	COG2840	Smr protein MutS2
AXK16_RS14180	COG0583	DNA-binding transcription factor activity
AXK16_RS14190	COG1473	amidohydrolase
AXK16_RS14195	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AXK16_RS14225	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AXK16_RS14230	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AXK16_RS14250	COG0531	amino acid
AXK16_RS14260	COG3136	membrane protein required for alginate biosynthesis
AXK16_RS14265	COG0745	RESPONSE REGULATOR receiver
AXK16_RS14275	COG2205	protein histidine kinase activity
AXK16_RS14285	COG0114	fumarate hydratase activity
AXK16_RS14290	COG2801	Transposase and inactivated derivatives
AXK16_RS14300	COG3344	reverse transcriptase
AXK16_RS14305	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AXK16_RS14305	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AXK16_RS14310	COG1482	cell wall glycoprotein biosynthetic process
AXK16_RS14320	COG1609	Transcriptional regulator
AXK16_RS14325	COG1263	PTS System
AXK16_RS14325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXK16_RS14330	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AXK16_RS14355	COG2391	methyltransferase activity
AXK16_RS14360	COG0425	Belongs to the sulfur carrier protein TusA family
AXK16_RS14365	COG5562	phage envelope protein
AXK16_RS14370	COG0401	homolog of Blt101
AXK16_RS14375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AXK16_RS14380	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS14385	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AXK16_RS14395	COG0477	Major facilitator Superfamily
AXK16_RS14400	COG1113	amino acid transport
AXK16_RS14405	COG2988	succinylglutamate desuccinylase activity
AXK16_RS14410	COG3724	N-succinylarginine dihydrolase activity
AXK16_RS14415	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS14420	COG3138	arginine N-succinyltransferase
AXK16_RS14425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXK16_RS14430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXK16_RS14435	COG0667	Aldo Keto reductase
AXK16_RS14440	COG0583	DNA-binding transcription factor activity
AXK16_RS14465	COG4122	O-methyltransferase activity
AXK16_RS14470	COG1643	Atp-dependent helicase
AXK16_RS14485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AXK16_RS14490	COG3327	negative regulation of DNA-templated transcription, initiation
AXK16_RS14495	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AXK16_RS14500	COG0183	Belongs to the thiolase family
AXK16_RS14505	COG2050	protein possibly involved in aromatic compounds catabolism
AXK16_RS14510	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXK16_RS14515	COG1024	Enoyl-CoA hydratase
AXK16_RS14520	COG1024	Enoyl-CoA hydratase
AXK16_RS14525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXK16_RS14530	COG2151	metal-sulfur cluster biosynthetic enzyme
AXK16_RS14535	COG3396	Phenylacetate-CoA oxygenase
AXK16_RS14540	COG3460	Phenylacetate-CoA oxygenase
AXK16_RS14545	COG3396	Phenylacetate-CoA oxygenase
AXK16_RS14550	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS14550	COG2030	dehydratase
AXK16_RS14580	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS14585	COG2207	Transcriptional regulator
AXK16_RS14590	COG3784	Protein of unknown function (DUF1318)
AXK16_RS14600	COG2911	Protein conserved in bacteria
AXK16_RS14605	COG0586	Pfam SNARE associated Golgi protein
AXK16_RS14610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXK16_RS14615	COG3187	Heat shock protein
AXK16_RS14620	COG3042	response to heat
AXK16_RS14630	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXK16_RS14630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AXK16_RS14630	COG1013	pyruvate-flavodoxin oxidoreductase activity
AXK16_RS14630	COG0674	pyruvate-flavodoxin oxidoreductase activity
AXK16_RS14635	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXK16_RS14645	COG0589	response to stress
AXK16_RS14655	COG0513	Belongs to the DEAD box helicase family
AXK16_RS14675	COG1349	DNA-binding transcription factor activity
AXK16_RS14680	COG0673	inositol 2-dehydrogenase activity
AXK16_RS14700	COG1522	sequence-specific DNA binding
AXK16_RS14710	COG1448	Aminotransferase
AXK16_RS14715	COG2011	ABC-type metal ion transport system permease component
AXK16_RS14730	COG0436	Aminotransferase
AXK16_RS14735	COG0604	alcohol dehydrogenase
AXK16_RS14760	COG0583	DNA-binding transcription factor activity
AXK16_RS14780	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS14785	COG1309	transcriptional regulator
AXK16_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS14885	COG2885	chlorophyll binding
AXK16_RS14920	COG3344	reverse transcriptase
AXK16_RS15010	COG0741	lytic transglycosylase activity
AXK16_RS15010	COG1196	nuclear chromosome segregation
AXK16_RS15010	COG0739	heme binding
AXK16_RS15080	COG3567	Phage-associated protein, HI1409 family
AXK16_RS15085	COG1783	phage Terminase large subunit
AXK16_RS15105	COG3772	lysozyme
AXK16_RS15115	COG0484	heat shock protein binding
AXK16_RS15215	COG0582	viral genome integration into host DNA
AXK16_RS15220	COG0693	protein deglycase activity
AXK16_RS15225	COG1078	dGTPase activity
AXK16_RS15230	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS15235	COG0583	DNA-binding transcription factor activity
AXK16_RS15285	COG4166	transmembrane transport
AXK16_RS15290	COG2866	Carboxypeptidase
AXK16_RS15295	COG4948	Mandelate Racemase Muconate Lactonizing
AXK16_RS15300	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AXK16_RS15305	COG3180	Ammonia monooxygenase
AXK16_RS15315	COG1486	melibiose metabolic process
AXK16_RS15320	COG0583	DNA-binding transcription factor activity
AXK16_RS15330	COG3106	COG3106 Predicted ATPase
AXK16_RS15340	COG1983	PspC domain protein
AXK16_RS15350	COG1842	Phage shock protein A
AXK16_RS15355	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AXK16_RS15365	COG1473	amidohydrolase
AXK16_RS15380	COG0702	epimerase
AXK16_RS15395	COG2135	peptidase activity
AXK16_RS15405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXK16_RS15410	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AXK16_RS15415	COG3344	reverse transcriptase
AXK16_RS15425	COG3344	reverse transcriptase
AXK16_RS15510	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXK16_RS15570	COG1196	nuclear chromosome segregation
AXK16_RS15660	COG3728	DNA packaging
AXK16_RS15660	COG5484	DNA packaging
AXK16_RS15715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AXK16_RS15820	COG4171	peptide transport system, permease
AXK16_RS15835	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AXK16_RS15845	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AXK16_RS15850	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXK16_RS15850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXK16_RS15865	COG1349	DNA-binding transcription factor activity
AXK16_RS15875	COG0023	Translation Initiation Factor
AXK16_RS15885	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AXK16_RS15890	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AXK16_RS15895	COG0671	phosphoesterase, PA-phosphatase related
AXK16_RS15905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AXK16_RS15940	COG0616	signal peptide processing
AXK16_RS15955	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AXK16_RS15965	COG0583	DNA-binding transcription factor activity
AXK16_RS15975	COG0009	L-threonylcarbamoyladenylate synthase
AXK16_RS15985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXK16_RS15990	COG0512	Glutamine amidotransferase of anthranilate synthase
AXK16_RS15990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXK16_RS15995	COG0134	indole-3-glycerol-phosphate synthase activity
AXK16_RS15995	COG0135	phosphoribosylanthranilate isomerase activity
AXK16_RS16050	COG4774	siderophore transport
AXK16_RS16060	COG3047	cAMP biosynthetic process
AXK16_RS16065	COG0727	PFAM Uncharacterised protein family (UPF0153)
AXK16_RS16095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXK16_RS16100	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS16105	COG1988	membrane-bound metal-dependent
AXK16_RS16110	COG1823	symporter activity
AXK16_RS16130	COG1486	melibiose metabolic process
AXK16_RS16140	COG1447	Phosphotransferase system cellobiose-specific component IIA
AXK16_RS16150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXK16_RS16155	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXK16_RS16165	COG0322	excinuclease ABC activity
AXK16_RS16170	COG3678	ATP-independent chaperone mediated protein folding
AXK16_RS16180	COG3724	N-succinylarginine dihydrolase activity
AXK16_RS16190	COG3138	arginine N-succinyltransferase
AXK16_RS16200	COG0708	Exodeoxyribonuclease III
AXK16_RS16205	COG0398	Pfam SNARE associated Golgi protein
AXK16_RS16210	COG0398	Pfam SNARE associated Golgi protein
AXK16_RS16215	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXK16_RS16220	COG4134	Bacterial extracellular solute-binding protein
AXK16_RS16225	COG4135	transport system, permease component
AXK16_RS16230	COG4136	ATPase activity
AXK16_RS16235	COG2897	thiosulfate sulfurtransferase activity
AXK16_RS16240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXK16_RS16245	COG0494	nUDIX hydrolase
AXK16_RS16250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXK16_RS16260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXK16_RS16265	COG0709	Synthesizes selenophosphate from selenide and ATP
AXK16_RS16295	COG0778	Nitroreductase
AXK16_RS16300	COG0616	signal peptide processing
AXK16_RS16310	COG1335	isochorismatase
AXK16_RS16315	COG2814	Major facilitator Superfamily
AXK16_RS16320	COG1349	DNA-binding transcription factor activity
AXK16_RS16325	COG0667	Aldo Keto reductase
AXK16_RS16330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXK16_RS16335	COG0191	fructose-bisphosphate aldolase activity
AXK16_RS16345	COG2271	Major facilitator Superfamily
AXK16_RS16350	COG1063	alcohol dehydrogenase
AXK16_RS16365	COG3139	Protein of unknown function (DUF1315)
AXK16_RS16385	COG0656	L-ascorbic acid biosynthetic process
AXK16_RS16395	COG2766	serine protein kinase
AXK16_RS16410	COG0386	Belongs to the glutathione peroxidase family
AXK16_RS16430	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS16435	COG0583	DNA-binding transcription factor activity
AXK16_RS16440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXK16_RS16445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AXK16_RS16450	COG3344	reverse transcriptase
AXK16_RS16470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXK16_RS16480	COG2207	Transcriptional regulator
AXK16_RS16485	COG2807	transmembrane transport
AXK16_RS16490	COG0504	CTP synthase activity
AXK16_RS16500	COG3189	MarR family transcriptional regulator
AXK16_RS16505	COG3042	response to heat
AXK16_RS16510	COG2203	Gaf domain
AXK16_RS16510	COG2199	diguanylate cyclase activity
AXK16_RS16520	COG3182	Iron-regulated membrane protein
AXK16_RS16530	COG1560	Kdo2-lipid A biosynthetic process
AXK16_RS16545	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AXK16_RS16550	COG3706	GGDEF domain
AXK16_RS16555	COG0583	DNA-binding transcription factor activity
AXK16_RS16560	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AXK16_RS16585	COG1294	oxidase, subunit
AXK16_RS16590	COG1271	oxidase subunit
AXK16_RS16595	COG3546	catalase activity
AXK16_RS16600	COG3685	Protein conserved in bacteria
AXK16_RS16605	COG3685	Protein conserved in bacteria
AXK16_RS16610	COG3729	General stress protein
AXK16_RS16615	COG1063	alcohol dehydrogenase
AXK16_RS16620	COG3813	Protein conserved in bacteria
AXK16_RS16635	COG0640	Transcriptional regulator
AXK16_RS16640	COG0538	isocitrate dehydrogenase activity
AXK16_RS16645	COG1187	pseudouridine synthase activity
AXK16_RS16665	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXK16_RS16685	COG2205	protein histidine kinase activity
AXK16_RS16690	COG2850	peptidyl-arginine hydroxylation
AXK16_RS16710	COG1177	transmembrane transport
AXK16_RS16725	COG0318	PFAM AMP-dependent synthetase and ligase
AXK16_RS16735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AXK16_RS16745	COG4591	ABC-type transport system involved in lipoprotein release permease component
AXK16_RS16760	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXK16_RS16765	COG1388	LysM domain
AXK16_RS16765	COG1376	ErfK ybiS ycfS ynhG family protein
AXK16_RS16775	COG1309	transcriptional regulator
AXK16_RS16785	COG3134	Outer membrane lipoprotein
AXK16_RS16790	COG1252	NADH dehydrogenase
AXK16_RS16820	COG5633	Lipoprotein
AXK16_RS16825	COG0537	adenosine 5'-monophosphoramidase activity
AXK16_RS16835	COG0084	hydrolase, TatD family'
AXK16_RS16840	COG0470	DNA polymerase III
AXK16_RS16855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXK16_RS16860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXK16_RS16875	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AXK16_RS16895	COG1399	metal-binding, possibly nucleic acid-binding protein
AXK16_RS16910	COG1530	ribonuclease E activity
AXK16_RS16915	COG0583	DNA-binding transcription factor activity
AXK16_RS16920	COG2814	Major facilitator Superfamily
AXK16_RS16940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXK16_RS16990	COG1560	Kdo2-lipid A biosynthetic process
AXK16_RS17010	COG5645	(Lipo)protein
AXK16_RS17050	COG3381	protein complex oligomerization
AXK16_RS17075	COG0583	DNA-binding transcription factor activity
AXK16_RS17085	COG1335	isochorismatase
AXK16_RS17100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXK16_RS17105	COG1702	phosphate starvation-inducible protein PhoH
AXK16_RS17125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXK16_RS17135	COG3039	Transposase
AXK16_RS17140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXK16_RS17155	COG1309	transcriptional regulator
AXK16_RS17190	COG2233	PERMEase
AXK16_RS17200	COG3729	General stress protein
AXK16_RS17225	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS17235	COG0531	amino acid
AXK16_RS17245	COG0174	glutamine synthetase
AXK16_RS17250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AXK16_RS17255	COG1917	Cupin 2, conserved barrel domain protein
AXK16_RS17255	COG1396	sequence-specific DNA binding
AXK16_RS17265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXK16_RS17270	COG0583	DNA-binding transcription factor activity
AXK16_RS17275	COG0473	3-isopropylmalate dehydrogenase activity
AXK16_RS17285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXK16_RS17290	COG4638	Rieske (2fe-2S)
AXK16_RS17295	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS17305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXK16_RS17315	COG2200	EAL domain
AXK16_RS17320	COG2200	EAL domain
AXK16_RS17335	COG0670	Belongs to the BI1 family
AXK16_RS17350	COG2207	Transcriptional regulator
AXK16_RS17355	COG1881	PFAM PEBP family protein
AXK16_RS17370	COG1832	CoA-binding protein
AXK16_RS17380	COG0210	DNA helicase
AXK16_RS17385	COG3304	Inner membrane component domain
AXK16_RS17390	COG1289	transmembrane transporter activity
AXK16_RS17395	COG3070	regulator of competence-specific genes
AXK16_RS17420	COG1067	ATP-dependent peptidase activity
AXK16_RS17430	COG3130	regulation of translation
AXK16_RS17440	COG3009	Protein conserved in bacteria
AXK16_RS17445	COG3008	intermembrane lipid transfer
AXK16_RS17445	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AXK16_RS17450	COG2995	paraquat-inducible protein a
AXK16_RS17455	COG0488	(ABC) transporter
AXK16_RS17465	COG3217	Mosc domain protein beta barrel domain protein
AXK16_RS17465	COG0633	Ferredoxin
AXK16_RS17480	COG0431	NADPH-dependent FMN reductase
AXK16_RS17485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXK16_RS17490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXK16_RS17495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXK16_RS17505	COG0308	aminopeptidase N
AXK16_RS17535	COG1522	sequence-specific DNA binding
AXK16_RS17545	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AXK16_RS17550	COG1448	Aminotransferase
AXK16_RS17555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXK16_RS17560	COG3108	Peptidase M15
AXK16_RS17570	COG2989	Protein conserved in bacteria
AXK16_RS17580	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AXK16_RS17590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXK16_RS17595	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AXK16_RS17600	COG3173	Aminoglycoside phosphotransferase
AXK16_RS17615	COG3214	Protein conserved in bacteria
AXK16_RS17630	COG2333	competence protein COMEC
AXK16_RS17630	COG0658	competence protein
AXK16_RS17640	COG0539	negative regulation of cytoplasmic translation
AXK16_RS17660	COG2323	membrane
AXK16_RS17665	COG1944	ATP diphosphatase activity
AXK16_RS17670	COG2116	formate transmembrane transporter activity
AXK16_RS17675	COG1882	Formate acetyltransferase
AXK16_RS17680	COG3344	reverse transcriptase
AXK16_RS17685	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AXK16_RS17690	COG0477	Major facilitator Superfamily
AXK16_RS17700	COG3302	dmso reductase anchor subunit
AXK16_RS17710	COG0243	molybdopterin cofactor binding
AXK16_RS17720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AXK16_RS17745	COG0492	ferredoxin-NADP+ reductase activity
AXK16_RS17750	COG4988	ABC transporter
AXK16_RS17755	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AXK16_RS17770	COG0542	response to heat
AXK16_RS17780	COG1278	Cold shock
AXK16_RS17795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK16_RS17800	COG3593	DNA synthesis involved in DNA repair
AXK16_RS17810	COG2431	L-lysine efflux transmembrane transporter activity
AXK16_RS17820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXK16_RS17830	COG0028	Belongs to the TPP enzyme family
AXK16_RS17835	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AXK16_RS17840	COG0702	epimerase
AXK16_RS17845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXK16_RS17850	COG3023	N-Acetylmuramoyl-L-alanine amidase
AXK16_RS17870	COG1126	abc transporter atp-binding protein
AXK16_RS17875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK16_RS17880	COG4215	(ABC) transporter
AXK16_RS17885	COG4160	amino acid transport
AXK16_RS17890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK16_RS17895	COG5002	protein histidine kinase activity
AXK16_RS17900	COG0745	RESPONSE REGULATOR receiver
AXK16_RS17915	COG1177	transmembrane transport
AXK16_RS17920	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXK16_RS17925	COG3842	ATPase activity
AXK16_RS17930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AXK16_RS18115	COG4695	Portal protein
AXK16_RS18140	COG3344	reverse transcriptase
AXK16_RS18155	COG3226	Transcriptional regulator
AXK16_RS18160	COG0738	Major facilitator superfamily
AXK16_RS18165	COG0561	phosphatase activity
AXK16_RS18170	COG2814	Major facilitator Superfamily
AXK16_RS18180	COG0671	phosphoesterase, PA-phosphatase related
AXK16_RS18185	COG1349	DNA-binding transcription factor activity
AXK16_RS18190	COG1686	Belongs to the peptidase S11 family
AXK16_RS18195	COG0625	glutathione transferase activity
AXK16_RS18200	COG2133	pyrroloquinoline quinone binding
AXK16_RS18210	COG2223	nitrite transmembrane transporter activity
AXK16_RS18240	COG0747	negative chemotaxis
AXK16_RS18255	COG0303	'Molybdopterin
AXK16_RS18260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXK16_RS18265	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AXK16_RS18270	COG1882	Formate acetyltransferase
AXK16_RS18275	COG0561	phosphatase activity
AXK16_RS18285	COG1609	Transcriptional regulator
AXK16_RS18290	COG2271	Major facilitator Superfamily
AXK16_RS18305	COG0488	(ABC) transporter
AXK16_RS18310	COG2365	Tyrosine phosphatase family
AXK16_RS18315	COG1376	ErfK ybiS ycfS ynhG family protein
AXK16_RS18320	COG2188	Transcriptional regulator
AXK16_RS18325	COG2723	6-phospho-beta-galactosidase activity
AXK16_RS18330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AXK16_RS18335	COG1321	iron dependent repressor
AXK16_RS18345	COG2194	sulfuric ester hydrolase activity
AXK16_RS18350	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AXK16_RS18365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK16_RS18370	COG0765	amino acid transport
AXK16_RS18375	COG1126	abc transporter atp-binding protein
AXK16_RS18380	COG0668	transmembrane transport
AXK16_RS18390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXK16_RS18400	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AXK16_RS18410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXK16_RS18415	COG1199	ATP-dependent helicase activity
AXK16_RS18420	COG0513	Belongs to the DEAD box helicase family
AXK16_RS18425	COG3958	Transketolase
AXK16_RS18435	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS18440	COG2271	Major facilitator Superfamily
AXK16_RS18445	COG0583	DNA-binding transcription factor activity
AXK16_RS18450	COG1309	transcriptional regulator
AXK16_RS18455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK16_RS18460	COG1131	(ABC) transporter
AXK16_RS18465	COG0842	Transport permease protein
AXK16_RS18470	COG0842	Transport permease protein
AXK16_RS18480	COG3568	Endonuclease Exonuclease Phosphatase
AXK16_RS18485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXK16_RS18490	COG0392	lysyltransferase activity
AXK16_RS18495	COG0670	Belongs to the BI1 family
AXK16_RS18500	COG0314	molybdopterin synthase activity
AXK16_RS18505	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AXK16_RS18515	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXK16_RS18540	COG0745	RESPONSE REGULATOR receiver
AXK16_RS18545	COG0642	Histidine kinase
AXK16_RS18560	COG3344	reverse transcriptase
AXK16_RS18585	COG2226	methyltransferase
AXK16_RS18610	COG1881	PFAM PEBP family protein
AXK16_RS18645	COG4677	pectinesterase activity
AXK16_RS18675	COG0789	Transcriptional regulator
AXK16_RS18680	COG2200	EAL domain
AXK16_RS18705	COG0561	phosphatase activity
AXK16_RS18710	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AXK16_RS18730	COG2005	Transcriptional regulator
AXK16_RS18730	COG3585	molybdate ion transport
AXK16_RS18735	COG1119	ATPase activity
AXK16_RS18745	COG1085	galactose-1-phosphate uridylyltransferase
AXK16_RS18755	COG2017	converts alpha-aldose to the beta-anomer
AXK16_RS18765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXK16_RS18780	COG3201	nicotinamide mononucleotide transporter
AXK16_RS18785	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AXK16_RS18825	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AXK16_RS18830	COG2885	chlorophyll binding
AXK16_RS18840	COG3064	Membrane
AXK16_RS18845	COG0848	biopolymer transport protein
AXK16_RS18850	COG0811	peptide transport
AXK16_RS18855	COG0824	Thioesterase
AXK16_RS18860	COG3790	cyd operon protein YbgE
AXK16_RS18865	COG4890	Cyd operon protein YbgT
AXK16_RS18870	COG1294	oxidase, subunit
AXK16_RS18875	COG1271	oxidase subunit
AXK16_RS18885	COG3344	reverse transcriptase
AXK16_RS18890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AXK16_RS18900	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXK16_RS18910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AXK16_RS18915	COG1053	succinate dehydrogenase
AXK16_RS18920	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AXK16_RS18925	COG2009	succinate dehydrogenase
AXK16_RS18965	COG1984	allophanate hydrolase subunit 2
AXK16_RS18970	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AXK16_RS18985	COG0415	Belongs to the DNA photolyase family
AXK16_RS19015	COG2205	protein histidine kinase activity
AXK16_RS19020	COG0745	RESPONSE REGULATOR receiver
AXK16_RS19030	COG0033	Phosphoglucomutase
AXK16_RS19040	COG0596	Alpha beta hydrolase
AXK16_RS19055	COG0735	belongs to the Fur family
AXK16_RS19105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AXK16_RS19110	COG1940	carbohydrate kinase activity
AXK16_RS19110	COG1846	Transcriptional regulator
AXK16_RS19115	COG0647	UMP catabolic process
AXK16_RS19120	COG0367	asparagine synthase
AXK16_RS19165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXK16_RS19175	COG1702	phosphate starvation-inducible protein PhoH
AXK16_RS19185	COG4535	Mg2 and Co2 transporter CorC
AXK16_RS19200	COG0765	amino acid transport
AXK16_RS19205	COG0765	amino acid transport
AXK16_RS19225	COG2888	peptidyl-tyrosine sulfation
AXK16_RS19240	COG1466	dna polymerase III delta subunit
AXK16_RS19260	COG0799	negative regulation of ribosome biogenesis
AXK16_RS19270	COG0768	penicillin binding
AXK16_RS19275	COG0772	Belongs to the SEDS family
AXK16_RS19280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AXK16_RS19285	COG1686	Belongs to the peptidase S11 family
AXK16_RS19300	COG0583	DNA-binding transcription factor activity
AXK16_RS19315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXK16_RS19335	COG3069	C4-dicarboxylate transmembrane transporter activity
AXK16_RS19340	COG3719	Belongs to the RNase T2 family
AXK16_RS19345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXK16_RS19365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXK16_RS19370	COG0583	DNA-binding transcription factor activity
AXK16_RS19375	COG3969	phosphoadenosine phosphosulfate
AXK16_RS19380	COG1475	DNA binding
AXK16_RS19385	COG0436	Aminotransferase
AXK16_RS19415	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS19420	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS19430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXK16_RS19445	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AXK16_RS19455	COG0402	S-adenosylhomocysteine deaminase activity
AXK16_RS19465	COG0483	inositol monophosphate 1-phosphatase activity
AXK16_RS19470	COG2271	Major facilitator Superfamily
AXK16_RS19500	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS19505	COG1129	ABC transporter
AXK16_RS19510	COG0371	Dehydrogenase
AXK16_RS19515	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS19530	COG2879	small protein
AXK16_RS19545	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS19550	COG3433	isochorismatase activity
AXK16_RS19550	COG1535	isochorismatase
AXK16_RS19555	COG1021	2,3-dihydroxybenzoate-AMP ligase
AXK16_RS19560	COG1169	isochorismate synthase
AXK16_RS19565	COG4592	Periplasmic binding protein
AXK16_RS19575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXK16_RS19580	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXK16_RS19585	COG1120	ATPase activity
AXK16_RS19590	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AXK16_RS19590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXK16_RS19595	COG3251	PFAM MbtH domain protein
AXK16_RS19600	COG2382	esterase
AXK16_RS19615	COG2977	Belongs to the P-Pant transferase superfamily
AXK16_RS19620	COG3958	Transketolase
AXK16_RS19625	COG3959	Transketolase, thiamine diphosphate binding domain
AXK16_RS19640	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AXK16_RS19645	COG1879	ABC-type sugar transport system periplasmic component
AXK16_RS19655	COG1129	ABC transporter
AXK16_RS19660	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS19670	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS19680	COG0583	DNA-binding transcription factor activity
AXK16_RS19725	COG0747	negative chemotaxis
AXK16_RS19730	COG0601	transmembrane transport
AXK16_RS19735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXK16_RS19740	COG0444	Belongs to the ABC transporter superfamily
AXK16_RS19745	COG4608	Belongs to the ABC transporter superfamily
AXK16_RS19760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXK16_RS19765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXK16_RS19770	COG4221	oxidoreductase activity
AXK16_RS19780	COG4215	(ABC) transporter
AXK16_RS19785	COG0765	amino acid transport
AXK16_RS19790	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AXK16_RS19805	COG0697	spore germination
AXK16_RS19815	COG3698	Phosphodiester glycosidase
AXK16_RS19820	COG2801	Transposase and inactivated derivatives
AXK16_RS19870	COG2315	Protein conserved in bacteria
AXK16_RS19875	COG0778	Nitroreductase
AXK16_RS19885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXK16_RS19895	COG3716	PTS system mannose fructose sorbose family IID component
AXK16_RS19900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXK16_RS19905	COG2222	sugar isomerase
AXK16_RS19930	COG0477	Major facilitator Superfamily
AXK16_RS19935	COG0668	transmembrane transport
AXK16_RS19965	COG3188	usher protein
AXK16_RS19980	COG2771	luxR family
AXK16_RS19990	COG0673	inositol 2-dehydrogenase activity
AXK16_RS20000	COG2211	Major facilitator Superfamily
AXK16_RS20005	COG1113	amino acid transport
AXK16_RS20020	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS20025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXK16_RS20040	COG0531	amino acid
AXK16_RS20095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK16_RS20100	COG1473	amidohydrolase
AXK16_RS20125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXK16_RS20130	COG1120	ATPase activity
AXK16_RS20135	COG1566	PFAM secretion protein HlyD family protein
AXK16_RS20180	COG4211	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS20200	COG0673	inositol 2-dehydrogenase activity
AXK16_RS20230	COG3104	oligopeptide transport
AXK16_RS20235	COG1982	Orn Lys Arg decarboxylase major
AXK16_RS20240	COG0531	amino acid
AXK16_RS20250	COG3710	Transcriptional regulator
AXK16_RS20260	COG1560	Kdo2-lipid A biosynthetic process
AXK16_RS20280	COG3121	Chaperone
AXK16_RS20285	COG3539	Fimbrial protein
AXK16_RS20340	COG2501	S4 domain
AXK16_RS20350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AXK16_RS20370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AXK16_RS20375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AXK16_RS20390	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AXK16_RS20395	COG4181	ATPase activity
AXK16_RS20400	COG2755	lipolytic protein G-D-S-L family
AXK16_RS20405	COG0300	oxidoreductase activity
AXK16_RS20410	COG3118	belongs to the thioredoxin family
AXK16_RS20420	COG0390	transport system, permease component
AXK16_RS20425	COG4619	ABC transporter
AXK16_RS20430	COG0330	HflC and HflK could
AXK16_RS20435	COG1585	Membrane protein implicated in regulation of membrane protease activity
AXK16_RS20450	COG3735	TraB family
AXK16_RS20455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXK16_RS20465	COG2223	nitrite transmembrane transporter activity
AXK16_RS20470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXK16_RS20470	COG4651	solute:proton antiporter activity
AXK16_RS20475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXK16_RS20515	COG2832	Protein of unknown function (DUF454)
AXK16_RS20520	COG3923	Primosomal replication protein n
AXK16_RS20530	COG5464	transposase or invertase
AXK16_RS20535	COG1196	nuclear chromosome segregation
AXK16_RS20535	COG3264	Mechanosensitive ion channel
AXK16_RS20540	COG1309	transcriptional regulator
AXK16_RS20545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK16_RS20550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXK16_RS20565	COG0110	maltose O-acetyltransferase activity
AXK16_RS20610	COG1874	Beta-galactosidase
AXK16_RS20615	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AXK16_RS20620	COG3833	ABC-type maltose transport systems, permease component
AXK16_RS20625	COG1175	transmembrane transport
AXK16_RS20630	COG2182	Extracellular solute-binding protein
AXK16_RS20640	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AXK16_RS20655	COG2364	Membrane
AXK16_RS20685	COG3695	enzyme binding
AXK16_RS20690	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AXK16_RS20695	COG1946	Acyl-CoA thioesterase
AXK16_RS20700	COG0004	ammonium transporteR
AXK16_RS20705	COG0347	Belongs to the P(II) protein family
AXK16_RS20710	COG1132	(ABC) transporter
AXK16_RS20715	COG1132	(ABC) transporter
AXK16_RS20720	COG1522	sequence-specific DNA binding
AXK16_RS20735	COG4533	DNA binding
AXK16_RS20745	COG0824	Thioesterase
AXK16_RS20750	COG1555	photosystem II stabilization
AXK16_RS20755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXK16_RS20760	COG0776	regulation of translation
AXK16_RS20765	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXK16_RS20770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AXK16_RS20790	COG0271	Belongs to the BolA IbaG family
AXK16_RS20795	COG3056	Lipoprotein
AXK16_RS20800	COG2223	nitrite transmembrane transporter activity
AXK16_RS20805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AXK16_RS20810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXK16_RS20815	COG1845	cytochrome c oxidase, subunit III
AXK16_RS20820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AXK16_RS20835	COG1414	Transcriptional regulator
AXK16_RS20840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXK16_RS20845	COG1053	succinate dehydrogenase
AXK16_RS20855	COG1053	succinate dehydrogenase
AXK16_RS20870	COG0673	inositol 2-dehydrogenase activity
AXK16_RS20875	COG2814	Major facilitator Superfamily
AXK16_RS20885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXK16_RS20890	COG0693	protein deglycase activity
AXK16_RS20910	COG0142	geranyltranstransferase activity
AXK16_RS20925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AXK16_RS20945	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXK16_RS20945	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXK16_RS20955	COG4238	major outer membrane lipoprotein
AXK16_RS20975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXK16_RS20980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXK16_RS20985	COG1862	Preprotein translocase
AXK16_RS21005	COG0450	alkyl hydroperoxide reductase
AXK16_RS21010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS21025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXK16_RS21045	COG1335	isochorismatase
AXK16_RS21050	COG0583	DNA-binding transcription factor activity
AXK16_RS21055	COG0366	Alpha amylase catalytic
AXK16_RS21080	COG0420	3'-5' exonuclease activity
AXK16_RS21085	COG0419	ATPase involved in DNA repair
AXK16_RS21105	COG4126	flavin adenine dinucleotide binding
AXK16_RS21115	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AXK16_RS21120	COG3416	Protein conserved in bacteria
AXK16_RS21130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AXK16_RS21140	COG1785	Belongs to the alkaline phosphatase family
AXK16_RS21180	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AXK16_RS21185	COG1335	isochorismatase
AXK16_RS21190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXK16_RS21195	COG0113	porphobilinogen synthase activity
AXK16_RS21205	COG2175	clavaminate synthase activity
AXK16_RS21210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXK16_RS21215	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXK16_RS21220	COG4521	taurine ABC transporter
AXK16_RS21225	COG2040	homocysteine
AXK16_RS21230	COG0833	amino acid
AXK16_RS21240	COG4303	Ethanolamine ammonia lyase large subunit
AXK16_RS21245	COG4302	ethanolamine ammonia-lyase activity
AXK16_RS21275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK16_RS21280	COG1126	abc transporter atp-binding protein
AXK16_RS21285	COG0765	amino acid transport
AXK16_RS21290	COG0765	amino acid transport
AXK16_RS21305	COG3188	usher protein
AXK16_RS21330	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AXK16_RS21340	COG3639	organic phosphonate transmembrane transporter activity
AXK16_RS21370	COG0791	NLP P60 protein
AXK16_RS21395	COG0582	viral genome integration into host DNA
AXK16_RS21400	COG1192	Involved in chromosome partitioning
AXK16_RS21465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXK16_RS21470	COG0022	dehydrogenase e1 component
AXK16_RS21475	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXK16_RS21480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXK16_RS21505	COG1070	Carbohydrate kinase
AXK16_RS21510	COG1028	Short-chain dehydrogenase reductase Sdr
AXK16_RS21515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXK16_RS21520	COG3775	system Galactitol-specific IIC component
AXK16_RS21525	COG0625	glutathione transferase activity
AXK16_RS21530	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AXK16_RS21550	COG0579	oxidoreductase
AXK16_RS21555	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS21560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXK16_RS21565	COG1113	amino acid transport
AXK16_RS21570	COG1802	Transcriptional regulator
AXK16_RS21590	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXK16_RS21595	COG0454	-acetyltransferase
AXK16_RS21610	COG2991	Protein conserved in bacteria
AXK16_RS21625	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AXK16_RS21630	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AXK16_RS21650	COG3034	peptidoglycan biosynthetic process
AXK16_RS21655	COG0121	glutamine amidotransferase
AXK16_RS21665	COG1960	acyl-CoA dehydrogenase activity
AXK16_RS21670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXK16_RS21680	COG0583	DNA-binding transcription factor activity
AXK16_RS21695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXK16_RS21705	COG2226	methyltransferase
AXK16_RS21715	COG0741	lytic transglycosylase activity
AXK16_RS21715	COG1388	LysM domain
AXK16_RS21720	COG2226	methyltransferase
AXK16_RS21730	COG2814	Major facilitator Superfamily
AXK16_RS21735	COG0583	DNA-binding transcription factor activity
AXK16_RS21740	COG0656	L-ascorbic acid biosynthetic process
AXK16_RS21775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AXK16_RS21785	COG2011	ABC-type metal ion transport system permease component
AXK16_RS21790	COG1464	Belongs to the NlpA lipoprotein family
AXK16_RS21800	COG1720	tRNA m6t6A37 methyltransferase activity
AXK16_RS21810	COG0791	NLP P60 protein
AXK16_RS21815	COG3015	lipoprotein NlpE involved in copper resistance
AXK16_RS21820	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AXK16_RS21835	COG4568	rho-dependent transcription termination
AXK16_RS21845	COG0346	lactoylglutathione lyase activity
AXK16_RS21890	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AXK16_RS21900	COG0750	zinc metalloprotease
AXK16_RS21905	COG0575	Belongs to the CDS family
AXK16_RS21920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AXK16_RS21945	COG0024	Methionine aminopeptidase
AXK16_RS21950	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AXK16_RS21965	COG3835	regulator
AXK16_RS21970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXK16_RS21990	COG2860	membrane
AXK16_RS22010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXK16_RS22015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXK16_RS22020	COG1120	ATPase activity
AXK16_RS22025	COG4774	siderophore transport
AXK16_RS22030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXK16_RS22120	COG1643	Atp-dependent helicase
AXK16_RS22125	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AXK16_RS22145	COG0617	tRNA 3'-terminal CCA addition
AXK16_RS22170	COG0726	polysaccharide deacetylase
AXK16_RS22175	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS22180	COG0842	Transport permease protein
AXK16_RS22185	COG1131	(ABC) transporter
AXK16_RS22190	COG0288	reversible hydration of carbon dioxide
AXK16_RS22200	COG4993	Dehydrogenase
AXK16_RS22205	COG2132	Multicopper oxidase
AXK16_RS22255	COG3064	Membrane
AXK16_RS22270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXK16_RS22275	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXK16_RS22280	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AXK16_RS22285	COG2186	Transcriptional regulator
AXK16_RS22290	COG1113	amino acid transport
AXK16_RS22295	COG2211	Major facilitator Superfamily
AXK16_RS22300	COG3940	Belongs to the glycosyl hydrolase 43 family
AXK16_RS22305	COG3725	Membrane protein required for beta-lactamase induction
AXK16_RS22310	COG3023	N-Acetylmuramoyl-L-alanine amidase
AXK16_RS22320	COG4969	Belongs to the N-Me-Phe pilin family
AXK16_RS22325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AXK16_RS22360	COG0494	nUDIX hydrolase
AXK16_RS22380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AXK16_RS22385	COG0849	cell division
AXK16_RS22425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXK16_RS22430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXK16_RS22435	COG0768	penicillin binding
AXK16_RS22460	COG1609	Transcriptional regulator
AXK16_RS22470	COG0028	Belongs to the TPP enzyme family
AXK16_RS22520	COG0738	Major facilitator superfamily
AXK16_RS22535	COG2271	Major facilitator Superfamily
AXK16_RS22540	COG2814	Major facilitator Superfamily
AXK16_RS22560	COG1178	ABC-type Fe3 transport system permease component
AXK16_RS22570	COG0586	Pfam SNARE associated Golgi protein
AXK16_RS22590	COG0235	Class ii aldolase
AXK16_RS22595	COG0417	DNA replication proofreading
AXK16_RS22605	COG0564	pseudouridine synthase activity
AXK16_RS22620	COG3493	citrate carrier protein
AXK16_RS22635	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AXK16_RS22640	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AXK16_RS22650	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AXK16_RS22700	COG0505	Belongs to the CarA family
AXK16_RS22790	COG1047	Peptidyl-prolyl cis-trans
AXK16_RS22805	COG0196	riboflavin kinase activity
AXK16_RS22825	COG0583	DNA-binding transcription factor activity
AXK16_RS22850	COG4735	regulation of single-species biofilm formation
AXK16_RS22855	COG1584	GPR1 FUN34 yaaH family protein
AXK16_RS22860	COG0477	Major facilitator Superfamily
AXK16_RS22865	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXK16_RS22870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AXK16_RS22875	COG1115	amino acid carrier protein
AXK16_RS22890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AXK16_RS22900	COG0527	aspartate kinase activity
AXK16_RS22900	COG0460	homoserine dehydrogenase
AXK16_RS22910	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AXK16_RS22920	COG0745	RESPONSE REGULATOR receiver
AXK16_RS22925	COG4452	Inner membrane protein CreD
AXK16_RS22930	COG2205	protein histidine kinase activity
AXK16_RS22935	COG0745	RESPONSE REGULATOR receiver
AXK16_RS22940	COG3045	CreA protein
AXK16_RS22945	COG2207	Transcriptional regulator
AXK16_RS22945	COG3708	Transcriptional regulator
AXK16_RS22965	COG0741	lytic transglycosylase activity
AXK16_RS22975	COG0488	(ABC) transporter
AXK16_RS22990	COG0560	Phosphoserine phosphatase
AXK16_RS23000	COG3726	membrane protein affecting hemolysin expression
AXK16_RS23030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXK16_RS23035	COG0084	hydrolase, TatD family'
AXK16_RS23040	COG4667	esterase of the alpha-beta hydrolase superfamily
AXK16_RS23050	COG2823	Periplasmic or secreted lipoprotein
AXK16_RS23065	COG0456	acetyltransferase
AXK16_RS23070	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AXK16_RS23100	COG3706	GGDEF domain
AXK16_RS23105	COG4114	ferric iron reductase
AXK16_RS23115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXK16_RS23120	COG2197	response regulator
AXK16_RS23125	COG2197	response regulator
AXK16_RS23145	COG2966	Psort location CytoplasmicMembrane, score
AXK16_RS23160	COG1484	DNA-dependent DNA replication
AXK16_RS23175	COG5464	transposase or invertase
AXK16_RS23185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXK16_RS23190	COG3716	PTS system mannose fructose sorbose family IID component
AXK16_RS23195	COG3715	PTS system
AXK16_RS23210	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AXK16_RS23210	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AXK16_RS23225	COG1802	Transcriptional regulator
AXK16_RS23230	COG2271	Major facilitator Superfamily
AXK16_RS23235	COG1214	PFAM Peptidase M22, glycoprotease
AXK16_RS23235	COG0456	acetyltransferase
AXK16_RS23245	COG1737	Transcriptional regulator
AXK16_RS23250	COG0800	Aldolase
AXK16_RS23255	COG3734	2-keto-3-deoxy-galactonokinase
AXK16_RS23305	COG1846	Transcriptional regulator
AXK16_RS23310	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXK16_RS23320	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS23325	COG3384	dioxygenase
AXK16_RS23335	COG3971	2-oxopent-4-enoate hydratase activity
AXK16_RS23355	COG2368	4-hydroxyphenylacetate
AXK16_RS23360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXK16_RS23375	COG1966	Carbon starvation protein
AXK16_RS23380	COG2879	small protein
AXK16_RS23385	COG0523	cobalamin synthesis protein
AXK16_RS23395	COG1012	belongs to the aldehyde dehydrogenase family
AXK16_RS23400	COG5464	transposase or invertase
AXK16_RS23405	COG2207	Transcriptional regulator
AXK16_RS23405	COG1917	Cupin 2, conserved barrel domain protein
AXK16_RS23415	COG2733	membrane
AXK16_RS23430	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AXK16_RS23435	COG1924	4 iron, 4 sulfur cluster binding
AXK16_RS23450	COG1566	PFAM secretion protein HlyD family protein
AXK16_RS23460	COG5457	Domain of unknown function (DUF1127)
AXK16_RS23465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXK16_RS23475	COG0583	DNA-binding transcription factor activity
AXK16_RS23480	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXK16_RS23490	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS23495	COG1129	ABC transporter
AXK16_RS23500	COG1879	ABC-type sugar transport system periplasmic component
AXK16_RS23510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK16_RS23515	COG1129	ABC transporter
AXK16_RS23515	COG0842	Transport permease protein
AXK16_RS23520	COG0842	Transport permease protein
AXK16_RS23550	COG2850	peptidyl-arginine hydroxylation
AXK16_RS23565	COG5002	protein histidine kinase activity
AXK16_RS23570	COG0745	RESPONSE REGULATOR receiver
AXK16_RS23580	COG1538	Outer membrane efflux protein
AXK16_RS23585	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK16_RS23590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK16_RS23595	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXK16_RS23610	COG0789	Transcriptional regulator
AXK16_RS23620	COG0300	oxidoreductase activity
AXK16_RS23635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AXK16_RS23655	COG3272	Protein of unknown function (DUF1722)
AXK16_RS23660	COG4580	involved in the transport of maltose and maltodextrins
AXK16_RS23670	COG2211	Major facilitator Superfamily
AXK16_RS23675	COG3507	Belongs to the glycosyl hydrolase 43 family
AXK16_RS23720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXK16_RS23720	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AXK16_RS23730	COG3344	reverse transcriptase
AXK16_RS23790	COG0582	viral genome integration into host DNA
AXK16_RS23800	COG0288	reversible hydration of carbon dioxide
AXK16_RS23805	COG0659	secondary active sulfate transmembrane transporter activity
AXK16_RS23810	COG1064	alcohol dehydrogenase
AXK16_RS23815	COG1175	transmembrane transport
AXK16_RS23820	COG0395	ABC-type sugar transport system, permease component
AXK16_RS23825	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXK16_RS23830	COG3842	ATPase activity
AXK16_RS23835	COG1653	transport
AXK16_RS23845	COG1082	Xylose isomerase domain protein TIM barrel
AXK16_RS23855	COG3962	Belongs to the TPP enzyme family
AXK16_RS23860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXK16_RS23865	COG0837	glucose binding
AXK16_RS23865	COG1737	Transcriptional regulator
AXK16_RS23890	COG3718	enzyme involved in inositol metabolism
AXK16_RS23905	COG0433	COG0433 Predicted ATPase
AXK16_RS23910	COG0795	lipopolysaccharide-transporting ATPase activity
AXK16_RS23915	COG0795	lipopolysaccharide-transporting ATPase activity
AXK16_RS23930	COG2927	DNA polymerase III (CHI subunit)
AXK16_RS23935	COG0525	valine-tRNA ligase activity
AXK16_RS23960	COG2188	Transcriptional regulator
AXK16_RS23965	COG1288	antiporter activity
AXK16_RS23970	COG1228	amidohydrolase
AXK16_RS23975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXK16_RS23980	COG2222	sugar isomerase
AXK16_RS23985	COG2731	YhcH YjgK YiaL family protein
AXK16_RS24025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXK16_RS24025	COG1263	PTS System
AXK16_RS24030	COG0366	Alpha amylase catalytic
AXK16_RS24035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXK16_RS24040	COG1486	melibiose metabolic process
AXK16_RS24060	COG0602	queuosine metabolic process
AXK16_RS24065	COG2026	Addiction module toxin, RelE StbE family
AXK16_RS24070	COG3077	Addiction module antitoxin, RelB DinJ family
AXK16_RS24075	COG3711	transcriptional antiterminator
AXK16_RS24075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK16_RS24080	COG2706	6-phosphogluconolactonase activity
AXK16_RS24095	COG3964	amidohydrolase
AXK16_RS24130	COG0312	modulator of DNA gyrase
AXK16_RS24150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AXK16_RS24160	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS24165	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS24170	COG1129	ABC transporter
AXK16_RS24175	COG1879	ABC-type sugar transport system periplasmic component
AXK16_RS24195	COG2105	PFAM AIG2 family protein
AXK16_RS24200	COG2911	Protein conserved in bacteria
AXK16_RS24205	COG0729	surface antigen
AXK16_RS24215	COG1253	flavin adenine dinucleotide binding
AXK16_RS24230	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AXK16_RS24245	COG1733	regulation of RNA biosynthetic process
AXK16_RS24250	COG0702	epimerase
AXK16_RS24260	COG0697	spore germination
AXK16_RS24270	COG1113	amino acid transport
AXK16_RS24275	COG0545	Peptidyl-prolyl cis-trans isomerase
AXK16_RS24280	COG3061	Opacity-associated protein A
AXK16_RS24290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AXK16_RS24295	COG2965	DNA replication, synthesis of RNA primer
AXK16_RS24355	COG1073	alpha beta
AXK16_RS24360	COG3650	response to hydrogen peroxide
AXK16_RS24370	COG1960	acyl-CoA dehydrogenase activity
AXK16_RS24375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXK16_RS24395	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AXK16_RS24405	COG0330	HflC and HflK could
AXK16_RS24410	COG0330	HflC and HflK could
AXK16_RS24415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXK16_RS24435	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXK16_RS24440	COG0802	atpase or kinase
AXK16_RS24445	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AXK16_RS24445	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AXK16_RS24450	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AXK16_RS24475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK16_RS24510	COG1053	succinate dehydrogenase
AXK16_RS24515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AXK16_RS24535	COG2076	Multidrug Resistance protein
AXK16_RS24540	COG5510	response to toxic substance
AXK16_RS24555	COG1509	lysine 2,3-aminomutase activity
AXK16_RS24625	COG0531	amino acid
AXK16_RS24630	COG3030	protein affecting phage T7 exclusion by the F plasmid
AXK16_RS24640	COG1027	Aspartate ammonia-lyase
AXK16_RS24645	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AXK16_RS24660	COG1309	transcriptional regulator
AXK16_RS24685	COG0457	Tetratricopeptide repeat
AXK16_RS24690	COG0726	polysaccharide deacetylase
AXK16_RS24690	COG1649	PFAM Uncharacterised BCR, COG1649
AXK16_RS24715	COG0861	Integral membrane protein TerC family
AXK16_RS24735	COG2801	Transposase and inactivated derivatives
AXK16_RS24755	COG1486	melibiose metabolic process
AXK16_RS24765	COG2169	Transcriptional regulator
AXK16_RS24780	COG2824	Alkylphosphonate utilization operon protein PhnA
AXK16_RS24785	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AXK16_RS24790	COG2188	Transcriptional regulator
AXK16_RS24795	COG3624	Phosphonate C-P lyase system protein PhnG
AXK16_RS24800	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AXK16_RS24805	COG3626	phosphonate metabolism
AXK16_RS24810	COG3627	carbon phosphorus lyase activity
AXK16_RS24815	COG4107	phosphonate C-P lyase system protein PhnK
AXK16_RS24820	COG4778	phosphonate C-P lyase system protein PhnL
AXK16_RS24825	COG3454	Phosphonate metabolism
AXK16_RS24835	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AXK16_RS24845	COG4191	Histidine kinase
AXK16_RS24845	COG0784	Response regulator, receiver
AXK16_RS24850	COG1129	ABC transporter
AXK16_RS24855	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS24895	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AXK16_RS24900	COG1301	dicarboxylic acid transport
AXK16_RS24910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXK16_RS24920	COG3162	membrane
AXK16_RS24950	COG3539	Fimbrial protein
AXK16_RS24955	COG1346	cytolysis
AXK16_RS24960	COG1380	Effector of murein hydrolase LrgA
AXK16_RS24965	COG0583	DNA-binding transcription factor activity
AXK16_RS24970	COG0025	NhaP-type Na H and K H
AXK16_RS24975	COG2252	PERMEase
AXK16_RS24985	COG0625	glutathione transferase activity
AXK16_RS24990	COG0789	Transcriptional regulator
AXK16_RS25000	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AXK16_RS25035	COG1234	tRNA 3'-trailer cleavage
AXK16_RS25040	COG1609	Transcriptional regulator
AXK16_RS25045	COG0483	inositol monophosphate 1-phosphatase activity
AXK16_RS25085	COG0741	lytic transglycosylase activity
AXK16_RS25100	COG2315	Protein conserved in bacteria
AXK16_RS25105	COG0432	Pfam Uncharacterised protein family UPF0047
AXK16_RS25120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXK16_RS25125	COG0305	Participates in initiation and elongation during chromosome replication
AXK16_RS25140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXK16_RS25150	COG0735	belongs to the Fur family
AXK16_RS25155	COG3237	CsbD-like
AXK16_RS25160	COG0534	Mate efflux family protein
AXK16_RS25170	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AXK16_RS25245	COG0251	oxidation-reduction process
AXK16_RS25255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AXK16_RS25270	COG0527	aspartate kinase activity
AXK16_RS25325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AXK16_RS25355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AXK16_RS25365	COG0456	acetyltransferase
AXK16_RS25370	COG3344	reverse transcriptase
AXK16_RS25415	COG4191	Histidine kinase
AXK16_RS25420	COG3678	ATP-independent chaperone mediated protein folding
AXK16_RS25455	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AXK16_RS25470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXK16_RS25475	COG2104	thiamine diphosphate biosynthetic process
AXK16_RS25495	COG3706	GGDEF domain
AXK16_RS25505	COG1447	Phosphotransferase system cellobiose-specific component IIA
AXK16_RS25510	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AXK16_RS25550	COG0250	Participates in transcription elongation, termination and antitermination
AXK16_RS25600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AXK16_RS25630	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AXK16_RS25640	COG1739	Uncharacterized protein family UPF0029
AXK16_RS25705	COG3165	ubiquinone biosynthetic process from chorismate
AXK16_RS25735	COG0583	DNA-binding transcription factor activity
AXK16_RS25740	COG0697	spore germination
AXK16_RS25745	COG0561	phosphatase activity
AXK16_RS25750	COG2267	carboxylic ester hydrolase activity
AXK16_RS25755	COG1280	lysine exporter protein (LysE YggA)
AXK16_RS25765	COG1280	lysine exporter protein (LysE YggA)
AXK16_RS25800	COG0210	DNA helicase
AXK16_RS25805	COG1011	Hydrolase
AXK16_RS25835	COG3072	Adenylate cyclase
AXK16_RS25850	COG2959	enzyme of heme biosynthesis
AXK16_RS25855	COG3071	HemY protein
AXK16_RS25900	COG2244	polysaccharide biosynthetic process
AXK16_RS25905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AXK16_RS25910	COG0456	acetyltransferase
AXK16_RS25915	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AXK16_RS25920	COG1088	dTDP-glucose 4,6-dehydratase activity
AXK16_RS25925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AXK16_RS25930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AXK16_RS25940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXK16_RS25945	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AXK16_RS25955	COG3118	belongs to the thioredoxin family
AXK16_RS25985	COG1811	Na channel or pump
AXK16_RS25995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXK16_RS26000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXK16_RS26015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXK16_RS26030	COG3978	acetolactate synthase activity
AXK16_RS26050	COG3085	chromosome segregation
AXK16_RS26125	COG0583	DNA-binding transcription factor activity
AXK16_RS26150	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AXK16_RS26165	COG3443	Belongs to the bacterial solute-binding protein 9 family
AXK16_RS26170	COG2207	Transcriptional regulator
AXK16_RS26180	COG0371	Dehydrogenase
AXK16_RS26185	COG0697	spore germination
AXK16_RS26195	COG0583	DNA-binding transcription factor activity
AXK16_RS26205	COG0737	Belongs to the 5'-nucleotidase family
AXK16_RS26215	COG0460	homoserine dehydrogenase
AXK16_RS26215	COG0527	aspartate kinase activity
AXK16_RS26220	COG0626	cystathionine gamma-synthase activity
AXK16_RS26230	COG3344	reverse transcriptase
AXK16_RS26240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AXK16_RS26245	COG1609	Transcriptional regulator
AXK16_RS26250	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AXK16_RS26285	COG3678	ATP-independent chaperone mediated protein folding
AXK16_RS26290	COG0745	RESPONSE REGULATOR receiver
AXK16_RS26295	COG2205	protein histidine kinase activity
AXK16_RS26300	COG2258	MOSC domain
AXK16_RS26305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXK16_RS26350	COG1129	ABC transporter
AXK16_RS26355	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS26360	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS26365	COG1454	alcohol dehydrogenase
AXK16_RS26375	COG2211	Major facilitator Superfamily
AXK16_RS26455	COG3383	formate dehydrogenase (NAD+) activity
AXK16_RS26455	COG0243	molybdopterin cofactor binding
AXK16_RS26460	COG3383	formate dehydrogenase (NAD+) activity
AXK16_RS26460	COG0243	molybdopterin cofactor binding
AXK16_RS26465	COG0437	4 iron, 4 sulfur cluster binding
AXK16_RS26470	COG2864	formate dehydrogenase
AXK16_RS26485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXK16_RS26490	COG0657	acetylesterase activity
AXK16_RS26495	COG0456	acetyltransferase
AXK16_RS26510	COG1011	Hydrolase
AXK16_RS26530	COG3852	Histidine kinase
AXK16_RS26540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXK16_RS26565	COG0204	Acyl-transferase
AXK16_RS26575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AXK16_RS26580	COG3084	Protein conserved in bacteria
AXK16_RS26590	COG1763	Mo-molybdopterin cofactor biosynthetic process
AXK16_RS26620	COG2186	Transcriptional regulator
AXK16_RS26625	COG0477	Major facilitator Superfamily
AXK16_RS26630	COG1609	Transcriptional regulator
AXK16_RS26635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXK16_RS26645	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXK16_RS26650	COG1129	ABC transporter
AXK16_RS26680	COG1522	sequence-specific DNA binding
AXK16_RS26685	COG0716	FMN binding
AXK16_RS26705	COG3312	ion transport
AXK16_RS26755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXK16_RS26760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXK16_RS26765	COG0573	inorganic phosphate transmembrane transporter activity
AXK16_RS26770	COG0581	inorganic phosphate transmembrane transporter activity
AXK16_RS26775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXK16_RS26780	COG0704	Plays a role in the regulation of phosphate uptake
AXK16_RS26790	COG2382	esterase
AXK16_RS26795	COG0363	glucosamine-6-phosphate deaminase activity
AXK16_RS26800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXK16_RS26810	COG2252	PERMEase
AXK16_RS26815	COG0431	NADPH-dependent FMN reductase
AXK16_RS26820	COG2091	lysine biosynthetic process via aminoadipic acid
AXK16_RS26850	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AXK16_RS26885	COG0187	DNA topoisomerase II activity
AXK16_RS26890	COG0561	phosphatase activity
AXK16_RS26905	COG2186	Transcriptional regulator
AXK16_RS26910	COG3734	2-keto-3-deoxy-galactonokinase
AXK16_RS26915	COG0800	Aldolase
AXK16_RS26925	COG2271	Major facilitator Superfamily
AXK16_RS26935	COG5645	(Lipo)protein
AXK16_RS26950	COG3645	SOS response
AXK16_RS26960	COG2188	Transcriptional regulator
AXK16_RS26975	COG2149	membrane
AXK16_RS26995	COG2610	gluconate transmembrane transporter activity
AXK16_RS27000	COG0583	DNA-binding transcription factor activity
AXK16_RS27005	COG2814	Major facilitator Superfamily
AXK16_RS27035	COG0440	acetolactate synthase activity
AXK16_RS27040	COG2197	response regulator
AXK16_RS27050	COG2271	Major facilitator Superfamily
AXK16_RS27095	COG2188	Transcriptional regulator
AXK16_RS27120	COG4580	involved in the transport of maltose and maltodextrins
AXK16_RS27125	COG1447	Phosphotransferase system cellobiose-specific component IIA
AXK16_RS27130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXK16_RS27130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXK16_RS27150	COG3384	dioxygenase
AXK16_RS27155	COG0583	DNA-binding transcription factor activity
AXK16_RS27160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AXK16_RS27165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXK16_RS27170	COG2828	Protein conserved in bacteria
AXK16_RS27185	COG0697	spore germination
AXK16_RS27200	COG2814	Major facilitator Superfamily
AXK16_RS27210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXK16_RS27245	COG0583	DNA-binding transcription factor activity
AXK16_RS27355	COG1192	Involved in chromosome partitioning
AXK16_RS27375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXK16_RS27390	COG3344	reverse transcriptase
AXK16_RS27420	COG2801	Transposase and inactivated derivatives
AXK16_RS27425	COG2963	transposase activity
AXK16_RS27435	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AXK16_RS27525	COG1484	DNA-dependent DNA replication
AXK16_RS27530	COG4584	PFAM Integrase catalytic
AXK16_RS27585	COG0616	signal peptide processing
AXK16_RS27745	COG4974	Belongs to the 'phage' integrase family
AXK16_RS27915	COG0633	Ferredoxin
AXK16_RS27960	COG0629	single-stranded DNA binding
AXK16_RS27970	COG0714	Associated with various cellular activities
AXK16_RS28005	COG5001	Diguanylate cyclase
AXK16_RS28030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXK16_RS28035	COG3344	reverse transcriptase
AXK16_RS28395	COG2135	peptidase activity
AXK16_RS28445	COG1349	DNA-binding transcription factor activity
AXK16_RS28450	COG2084	Dehydrogenase
AXK16_RS28455	COG3395	kinase activity
AXK16_RS28465	COG5001	Diguanylate cyclase
AXK16_RS28490	COG2826	transposase and inactivated derivatives, IS30 family
AXK16_RS28495	COG2963	transposase activity
AXK16_RS28505	COG0840	transmembrane signaling receptor activity
AXK16_RS28510	COG4372	Transposase
AXK16_RS28515	COG3436	PFAM IS66 Orf2 family protein
AXK16_RS28530	COG3173	Aminoglycoside phosphotransferase
AXK16_RS28610	COG3173	Aminoglycoside phosphotransferase
AXK16_RS28700	COG2186	Transcriptional regulator
AXK16_RS28710	COG0246	Mannitol dehydrogenase
AXK16_RS28730	COG3250	beta-galactosidase activity
AXK16_RS28735	COG1309	transcriptional regulator
AXK16_RS28740	COG3039	Transposase
AXK16_RS28765	COG1136	(ABC) transporter
AXK16_RS28780	COG1309	transcriptional regulator
AXK16_RS28815	COG0589	response to stress
AXK16_RS28820	COG0659	secondary active sulfate transmembrane transporter activity
AXK16_RS28860	COG0456	acetyltransferase
AXK16_RS28885	COG1324	tolerance protein
AXK16_RS28890	COG0673	inositol 2-dehydrogenase activity
AXK16_RS28940	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AXK16_RS28985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AXK16_RS29000	COG3039	Transposase
AXK16_RS29085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXK16_RS29085	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXK16_RS29270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXK16_RS29300	COG2003	Belongs to the UPF0758 family
AXK16_RS29365	COG0629	single-stranded DNA binding
AXK16_RS29495	COG3344	reverse transcriptase
AXK16_RS29600	COG1695	Transcriptional regulator
AXK16_RS29800	COG4644	lycopene metabolic process
AXK16_RS29825	COG3173	Aminoglycoside phosphotransferase