locus-tag	class	description
D5082_RS00005	COG0683	leucine binding
D5082_RS00010	COG0559	Belongs to the binding-protein-dependent transport system permease family
D5082_RS00060	COG0584	glycerophosphoryl diester phosphodiesterase
D5082_RS00070	COG0405	Gamma-glutamyltransferase
D5082_RS00075	COG1247	-acetyltransferase
D5082_RS00085	COG0673	inositol 2-dehydrogenase activity
D5082_RS00090	COG1741	Belongs to the pirin family
D5082_RS00095	COG1609	Transcriptional regulator
D5082_RS00100	COG3265	gluconokinase activity
D5082_RS00105	COG2610	gluconate transmembrane transporter activity
D5082_RS00115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D5082_RS00140	COG0058	SHG alpha-glucan phosphorylase activity
D5082_RS00145	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D5082_RS00160	COG1349	DNA-binding transcription factor activity
D5082_RS00175	COG0058	SHG alpha-glucan phosphorylase activity
D5082_RS00180	COG1640	4-alpha-glucanotransferase
D5082_RS00185	COG2610	gluconate transmembrane transporter activity
D5082_RS00195	COG1040	competence protein
D5082_RS00220	COG1918	ferrous iron import across plasma membrane
D5082_RS00225	COG2183	response to ionizing radiation
D5082_RS00230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D5082_RS00255	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D5082_RS00260	COG1011	Hydrolase
D5082_RS00270	COG0494	nUDIX hydrolase
D5082_RS00275	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D5082_RS00300	COG4796	Type ii and iii secretion system protein
D5082_RS00320	COG3266	domain, Protein
D5082_RS00325	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D5082_RS00330	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D5082_RS00355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D5082_RS00360	COG0402	S-adenosylhomocysteine deaminase activity
D5082_RS00365	COG0738	Major facilitator superfamily
D5082_RS00390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D5082_RS00395	COG1289	transmembrane transporter activity
D5082_RS00410	COG1765	OsmC-like protein
D5082_RS00415	COG3954	Phosphoribulokinase
D5082_RS00425	COG0429	hydrolase of the alpha beta-hydrolase fold
D5082_RS00435	COG0488	(ABC) transporter
D5082_RS00450	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
D5082_RS00455	COG1047	Peptidyl-prolyl cis-trans
D5082_RS00465	COG0545	Peptidyl-prolyl cis-trans isomerase
D5082_RS00470	COG2964	Protein conserved in bacteria
D5082_RS00525	COG0051	transcription antitermination factor activity, RNA binding
D5082_RS00550	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D5082_RS00565	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D5082_RS00630	COG0201	protein transport
D5082_RS00655	COG0202	RNA polymerase activity
D5082_RS00670	COG0789	Transcriptional regulator
D5082_RS00675	COG3036	rescue of stalled ribosome
D5082_RS00705	COG0758	DNA mediated transformation
D5082_RS00715	COG0551	DNA topoisomerase type I activity
D5082_RS00735	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D5082_RS00775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5082_RS00780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5082_RS00785	COG1309	transcriptional regulator
D5082_RS00810	COG4145	pantothenate transmembrane transporter activity
D5082_RS00815	COG3924	membrane
D5082_RS00820	COG0439	Biotin carboxylase
D5082_RS00825	COG0511	ligase activity, forming carbon-carbon bonds
D5082_RS00880	COG1077	Cell shape determining protein MreB Mrl
D5082_RS00885	COG1792	Involved in formation and maintenance of cell shape
D5082_RS00890	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D5082_RS00900	COG1530	ribonuclease E activity
D5082_RS00905	COG3164	Protein of unknown function
D5082_RS00910	COG0312	modulator of DNA gyrase
D5082_RS00915	COG0583	DNA-binding transcription factor activity
D5082_RS00930	COG1289	transmembrane transporter activity
D5082_RS00935	COG2732	(Barnase) inhibitor
D5082_RS00970	COG0471	metal ion transport
D5082_RS00975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D5082_RS00980	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D5082_RS01005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D5082_RS01010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D5082_RS01015	COG3105	Protein conserved in bacteria
D5082_RS01020	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D5082_RS01040	COG0625	glutathione transferase activity
D5082_RS01045	COG2969	positive regulation of protein catabolic process
D5082_RS01055	COG0493	'glutamate synthase
D5082_RS01060	COG0067	glutamate synthase
D5082_RS01060	COG0069	glutamate synthase activity
D5082_RS01060	COG0070	glutamate synthase
D5082_RS01065	COG1242	4 iron, 4 sulfur cluster binding
D5082_RS01070	COG2271	Major facilitator Superfamily
D5082_RS01075	COG1063	alcohol dehydrogenase
D5082_RS01080	COG1312	Catalyzes the dehydration of D-mannonate
D5082_RS01085	COG2198	Histidine kinase
D5082_RS01085	COG0784	Response regulator, receiver
D5082_RS01085	COG5002	protein histidine kinase activity
D5082_RS01090	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
D5082_RS01095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D5082_RS01100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS01110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS01115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D5082_RS01120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D5082_RS01125	COG1137	ATPase activity
D5082_RS01130	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
D5082_RS01135	COG3117	lipopolysaccharide transmembrane transporter activity
D5082_RS01140	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D5082_RS01150	COG0530	calcium, potassium:sodium antiporter activity
D5082_RS01160	COG1127	ABC transporter
D5082_RS01165	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D5082_RS01170	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D5082_RS01175	COG2854	intermembrane phospholipid transfer
D5082_RS01180	COG3113	response to antibiotic
D5082_RS01185	COG5007	Belongs to the BolA IbaG family
D5082_RS01195	COG3423	Transcriptional regulator
D5082_RS01200	COG0142	geranyltranstransferase activity
D5082_RS01215	COG0697	spore germination
D5082_RS01225	COG2027	D-alanyl-D-alanine carboxypeptidase
D5082_RS01235	COG1534	Rna-binding protein
D5082_RS01250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D5082_RS01255	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D5082_RS01265	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D5082_RS01305	COG0195	Participates in both transcription termination and antitermination
D5082_RS01355	COG0814	amino acid
D5082_RS01360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5082_RS01365	COG0826	peptidase U32
D5082_RS01370	COG0826	peptidase U32
D5082_RS01375	COG3154	lipid carrier protein
D5082_RS01380	COG3153	acetyltransferase
D5082_RS01395	COG0693	protein deglycase activity
D5082_RS01400	COG0702	epimerase
D5082_RS01405	COG0701	Predicted permease
D5082_RS01410	COG2823	Periplasmic or secreted lipoprotein
D5082_RS01430	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D5082_RS01435	COG2721	sulfolactate sulfo-lyase activity
D5082_RS01440	COG2271	Major facilitator Superfamily
D5082_RS01450	COG2084	Dehydrogenase
D5082_RS01455	COG1929	Belongs to the glycerate kinase type-1 family
D5082_RS01475	COG1741	Belongs to the pirin family
D5082_RS01480	COG0583	DNA-binding transcription factor activity
D5082_RS01485	COG3152	Membrane
D5082_RS01490	COG0435	Glutathione S-transferase
D5082_RS01495	COG2259	Doxx family
D5082_RS01505	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
D5082_RS01510	COG4575	ribosome binding
D5082_RS01515	COG1422	Protein of unknown function (DUF1090)
D5082_RS01525	COG0586	Pfam SNARE associated Golgi protein
D5082_RS01540	COG2271	Major facilitator Superfamily
D5082_RS01550	COG2721	sulfolactate sulfo-lyase activity
D5082_RS01565	COG0861	Integral membrane protein TerC family
D5082_RS01570	COG0673	inositol 2-dehydrogenase activity
D5082_RS01575	COG1451	nucleotide metabolic process
D5082_RS01595	COG0446	pyridine nucleotide-disulphide oxidoreductase
D5082_RS01595	COG1902	pentaerythritol trinitrate reductase activity
D5082_RS01650	COG1695	Transcriptional regulator
D5082_RS01655	COG2375	cellular response to nickel ion
D5082_RS01670	COG1461	Dihydroxyacetone kinase
D5082_RS01675	COG2376	Dihydroxyacetone kinase
D5082_RS01745	COG3247	response to pH
D5082_RS01755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5082_RS01755	COG2198	Histidine kinase
D5082_RS01755	COG2205	protein histidine kinase activity
D5082_RS01755	COG0784	Response regulator, receiver
D5082_RS01760	COG2197	response regulator
D5082_RS01785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D5082_RS01790	COG0358	DNA primase activity
D5082_RS01795	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D5082_RS01860	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D5082_RS01875	COG4991	sh3 domain protein
D5082_RS01880	COG3025	triphosphatase activity
D5082_RS01900	COG2960	long-chain fatty acid transporting porin activity
D5082_RS01915	COG3384	dioxygenase
D5082_RS01920	COG0754	glutathionylspermidine amidase activity
D5082_RS01935	COG0494	nUDIX hydrolase
D5082_RS01940	COG3151	Protein conserved in bacteria
D5082_RS01945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D5082_RS01950	COG3150	esterase
D5082_RS01960	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D5082_RS01965	COG2249	NAD(P)H dehydrogenase (quinone) activity
D5082_RS01970	COG0642	Histidine kinase
D5082_RS01980	COG3111	PFAM Bacterial OB fold (BOF) protein
D5082_RS01985	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D5082_RS01995	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D5082_RS02000	COG0204	Acyl-transferase
D5082_RS02005	COG2132	Multicopper oxidase
D5082_RS02010	COG1032	radical SAM domain protein
D5082_RS02020	COG0656	L-ascorbic acid biosynthetic process
D5082_RS02025	COG1979	alcohol dehydrogenase
D5082_RS02030	COG2207	Transcriptional regulator
D5082_RS02035	COG0586	Pfam SNARE associated Golgi protein
D5082_RS02040	COG0626	cystathionine gamma-synthase activity
D5082_RS02055	COG0848	biopolymer transport protein
D5082_RS02060	COG2211	Major facilitator Superfamily
D5082_RS02085	COG0625	glutathione transferase activity
D5082_RS02095	COG0754	glutathionylspermidine amidase activity
D5082_RS02100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5082_RS02120	COG0583	DNA-binding transcription factor activity
D5082_RS02125	COG0626	cystathionine gamma-synthase activity
D5082_RS02145	COG3121	Chaperone
D5082_RS02160	COG3121	Chaperone
D5082_RS02165	COG3121	Chaperone
D5082_RS02170	COG3188	usher protein
D5082_RS02200	COG1811	Na channel or pump
D5082_RS02210	COG1982	Orn Lys Arg decarboxylase major
D5082_RS02215	COG2211	Major facilitator Superfamily
D5082_RS02230	COG1194	a g-specific adenine glycosylase
D5082_RS02240	COG3171	Protein conserved in bacteria
D5082_RS02250	COG4214	carbohydrate transport
D5082_RS02265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D5082_RS02280	COG0762	integral membrane protein
D5082_RS02285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D5082_RS02290	COG2805	Type II/IV secretion system protein
D5082_RS02310	COG0189	ligase activity
D5082_RS02315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D5082_RS02320	COG2356	endonuclease I
D5082_RS02330	COG2814	Major facilitator Superfamily
D5082_RS02365	COG0501	Belongs to the peptidase M48B family
D5082_RS02370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D5082_RS02385	COG0191	fructose-bisphosphate aldolase activity
D5082_RS02390	COG0668	transmembrane transport
D5082_RS02400	COG2968	Membrane
D5082_RS02415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D5082_RS02420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D5082_RS02440	COG0006	proline dipeptidase activity
D5082_RS02445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D5082_RS02450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D5082_RS02470	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS02475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D5082_RS02495	COG2723	6-phospho-beta-galactosidase activity
D5082_RS02500	COG1737	Transcriptional regulator
D5082_RS02510	COG1272	protein, Hemolysin III
D5082_RS02520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D5082_RS02530	COG0716	FMN binding
D5082_RS02535	COG4974	Belongs to the 'phage' integrase family
D5082_RS02545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D5082_RS02565	COG1811	Na channel or pump
D5082_RS02575	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D5082_RS02580	COG0583	DNA-binding transcription factor activity
D5082_RS02585	COG4942	peptidase
D5082_RS02595	COG2814	Major facilitator Superfamily
D5082_RS02610	COG0667	Aldo Keto reductase
D5082_RS02650	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D5082_RS02655	COG1393	Belongs to the ArsC family
D5082_RS02670	COG1538	Outer membrane efflux protein
D5082_RS02675	COG1289	transmembrane transporter activity
D5082_RS02690	COG3592	Divergent 4Fe-4S mono-cluster
D5082_RS02695	COG2388	GCN5-related N-acetyl-transferase
D5082_RS02705	COG3539	Fimbrial protein
D5082_RS02710	COG3539	Fimbrial protein
D5082_RS02715	COG3539	Fimbrial protein
D5082_RS02720	COG3188	usher protein
D5082_RS02725	COG3121	Chaperone
D5082_RS02730	COG3539	Fimbrial protein
D5082_RS02740	COG4974	Belongs to the 'phage' integrase family
D5082_RS02745	COG0582	viral genome integration into host DNA
D5082_RS02755	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
D5082_RS02760	COG1846	Transcriptional regulator
D5082_RS02765	COG0697	spore germination
D5082_RS02815	COG0667	Aldo Keto reductase
D5082_RS02820	COG0814	amino acid
D5082_RS02835	COG0183	Belongs to the thiolase family
D5082_RS02850	COG0823	Involved in the tonB-independent uptake of proteins
D5082_RS02855	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS02860	COG2814	Major facilitator Superfamily
D5082_RS02890	COG3842	ATPase activity
D5082_RS02895	COG0395	ABC-type sugar transport system, permease component
D5082_RS02900	COG1175	transmembrane transport
D5082_RS02905	COG1917	Cupin 2, conserved barrel domain protein
D5082_RS02910	COG1794	racemase activity, acting on amino acids and derivatives
D5082_RS02915	COG0583	DNA-binding transcription factor activity
D5082_RS02925	COG1609	Transcriptional regulator
D5082_RS02930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS02935	COG2723	6-phospho-beta-galactosidase activity
D5082_RS02940	COG2186	Transcriptional regulator
D5082_RS02950	COG1609	Transcriptional regulator
D5082_RS02975	COG0667	Aldo Keto reductase
D5082_RS02985	COG0861	Integral membrane protein TerC family
D5082_RS03020	COG2165	general secretion pathway protein
D5082_RS03025	COG4795	General secretion pathway protein
D5082_RS03035	COG4967	type IV pilus modification protein PilV
D5082_RS03040	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D5082_RS03045	COG1025	Belongs to the peptidase M16 family
D5082_RS03050	COG1074	ATP-dependent DNA helicase activity
D5082_RS03055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D5082_RS03065	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D5082_RS03065	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D5082_RS03070	COG0860	N-Acetylmuramoyl-L-alanine amidase
D5082_RS03075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D5082_RS03105	COG4656	Part of a membrane complex involved in electron transport
D5082_RS03110	COG1454	alcohol dehydrogenase
D5082_RS03110	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS03140	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
D5082_RS03340	COG2885	chlorophyll binding
D5082_RS03375	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D5082_RS03380	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D5082_RS03385	COG2166	iron-sulfur cluster assembly
D5082_RS03390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D5082_RS03400	COG0583	DNA-binding transcription factor activity
D5082_RS03405	COG2363	Small membrane protein
D5082_RS03415	COG1349	DNA-binding transcription factor activity
D5082_RS03435	COG0738	Major facilitator superfamily
D5082_RS03440	COG0235	Class ii aldolase
D5082_RS03445	COG1454	alcohol dehydrogenase
D5082_RS03460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5082_RS03475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D5082_RS03480	COG2011	ABC-type metal ion transport system permease component
D5082_RS03485	COG1464	Belongs to the NlpA lipoprotein family
D5082_RS03495	COG0477	Major facilitator Superfamily
D5082_RS03505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5082_RS03510	COG1760	l-serine dehydratase
D5082_RS03515	COG0814	amino acid
D5082_RS03520	COG1611	Belongs to the LOG family
D5082_RS03540	COG3098	single-species biofilm formation
D5082_RS03545	COG0564	pseudouridine synthase activity
D5082_RS03550	COG0716	FMN binding
D5082_RS03555	COG2271	Major facilitator Superfamily
D5082_RS03560	COG4948	Mandelate Racemase Muconate Lactonizing
D5082_RS03565	COG4948	Mandelate Racemase Muconate Lactonizing
D5082_RS03570	COG1929	Belongs to the glycerate kinase type-1 family
D5082_RS03580	COG3437	response regulator, receiver
D5082_RS03580	COG2205	protein histidine kinase activity
D5082_RS03580	COG3850	Histidine kinase
D5082_RS03580	COG4999	Histidine kinase
D5082_RS03590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D5082_RS03595	COG3956	TIGRFAM MazG family protein
D5082_RS03615	COG0602	queuosine metabolic process
D5082_RS03620	COG0720	synthase
D5082_RS03640	COG2234	aminopeptidase activity
D5082_RS03700	COG4942	peptidase
D5082_RS03700	COG1388	LysM domain
D5082_RS03705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D5082_RS03730	COG0163	prenyltransferase activity
D5082_RS03735	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D5082_RS03780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D5082_RS03785	COG4558	Periplasmic binding protein
D5082_RS03790	COG3720	iron ion transport
D5082_RS03810	COG0679	Auxin Efflux Carrier
D5082_RS03825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D5082_RS03830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D5082_RS03835	COG1121	(ABC) transporter
D5082_RS03840	COG0803	Belongs to the bacterial solute-binding protein 9 family
D5082_RS03845	COG1609	Transcriptional regulator
D5082_RS03850	COG1940	carbohydrate kinase activity
D5082_RS03855	COG1447	Phosphotransferase system cellobiose-specific component IIA
D5082_RS03860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS03865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS03870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS03880	COG4580	involved in the transport of maltose and maltodextrins
D5082_RS03890	COG2723	6-phospho-beta-galactosidase activity
D5082_RS03900	COG0309	Hydrogenase expression formation protein (HypE)
D5082_RS03905	COG0409	Hydrogenase expression formation protein
D5082_RS03910	COG0298	carbon dioxide binding
D5082_RS03915	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D5082_RS03935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D5082_RS03940	COG0651	ATP synthesis coupled electron transport
D5082_RS03945	COG0650	Formate hydrogenlyase subunit 4
D5082_RS03950	COG3261	NADH dehydrogenase
D5082_RS03950	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
D5082_RS03955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D5082_RS03960	COG3260	NADH ubiquinone oxidoreductase 20
D5082_RS03970	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D5082_RS03980	COG2723	6-phospho-beta-galactosidase activity
D5082_RS03985	COG1263	PTS System
D5082_RS03985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D5082_RS03990	COG1609	Transcriptional regulator
D5082_RS03995	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D5082_RS04000	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
D5082_RS04005	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
D5082_RS04035	COG1349	DNA-binding transcription factor activity
D5082_RS04040	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS04055	COG3732	PTS system glucitol sorbitol-specific
D5082_RS04060	COG3730	PTS system glucitol sorbitol-specific
D5082_RS04065	COG2951	lytic endotransglycosylase activity
D5082_RS04075	COG1121	(ABC) transporter
D5082_RS04080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D5082_RS04090	COG1546	Belongs to the CinA family
D5082_RS04115	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D5082_RS04145	COG2823	Periplasmic or secreted lipoprotein
D5082_RS04150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D5082_RS04155	COG1238	metal cluster binding
D5082_RS04175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D5082_RS04180	COG2814	Major facilitator Superfamily
D5082_RS04185	COG1566	PFAM secretion protein HlyD family protein
D5082_RS04190	COG1846	Transcriptional regulator
D5082_RS04200	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D5082_RS04210	COG4176	ABC-type proline glycine betaine transport system permease component
D5082_RS04225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D5082_RS04235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D5082_RS04240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D5082_RS04245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5082_RS04250	COG4575	ribosome binding
D5082_RS04275	COG2916	Histone family protein nucleoid-structuring protein H-NS
D5082_RS04290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D5082_RS04295	COG0640	Transcriptional regulator
D5082_RS04305	COG0583	DNA-binding transcription factor activity
D5082_RS04310	COG3284	Transcriptional regulator
D5082_RS04320	COG3539	Fimbrial protein
D5082_RS04325	COG3121	Chaperone
D5082_RS04345	COG3188	usher protein
D5082_RS04355	COG3539	Fimbrial protein
D5082_RS04360	COG2197	response regulator
D5082_RS04375	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS04385	COG0235	Class ii aldolase
D5082_RS04395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5082_RS04430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5082_RS04435	COG2207	Transcriptional regulator
D5082_RS04435	COG3708	Transcriptional regulator
D5082_RS04465	COG2867	negative regulation of translational initiation
D5082_RS04480	COG0497	DNA recombination
D5082_RS04500	COG4536	flavin adenine dinucleotide binding
D5082_RS04505	COG4137	Cytochrome C assembly protein
D5082_RS04510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D5082_RS04545	COG2885	chlorophyll binding
D5082_RS04550	COG2199	diguanylate cyclase activity
D5082_RS04560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D5082_RS04565	COG0287	Prephenate dehydrogenase
D5082_RS04565	COG1605	Chorismate mutase
D5082_RS04575	COG1605	Chorismate mutase
D5082_RS04575	COG0077	Prephenate dehydratase
D5082_RS04585	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D5082_RS04590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D5082_RS04605	COG0542	response to heat
D5082_RS04630	COG0477	Major facilitator Superfamily
D5082_RS04635	COG5544	Lipoprotein
D5082_RS04640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D5082_RS04650	COG3148	PFAM DTW domain containing protein
D5082_RS04655	COG3118	belongs to the thioredoxin family
D5082_RS04660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D5082_RS04675	COG0513	Belongs to the DEAD box helicase family
D5082_RS04685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D5082_RS04695	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
D5082_RS04700	COG3026	antisigma factor binding
D5082_RS04705	COG3086	response to oxidative stress
D5082_RS04745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D5082_RS04800	COG1484	DNA-dependent DNA replication
D5082_RS04855	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D5082_RS04860	COG0484	heat shock protein binding
D5082_RS04880	COG3179	chitinase
D5082_RS04915	COG5484	DNA packaging
D5082_RS04915	COG3728	DNA packaging
D5082_RS05005	COG1196	nuclear chromosome segregation
D5082_RS05065	COG0681	Belongs to the peptidase S26 family
D5082_RS05085	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D5082_RS05095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D5082_RS05100	COG1737	Transcriptional regulator
D5082_RS05105	COG0560	Phosphoserine phosphatase
D5082_RS05120	COG0047	phosphoribosylformylglycinamidine synthase activity
D5082_RS05120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D5082_RS05130	COG2205	protein histidine kinase activity
D5082_RS05135	COG3170	Tfp pilus assembly protein FimV
D5082_RS05140	COG2204	response regulator
D5082_RS05145	COG0347	Belongs to the P(II) protein family
D5082_RS05150	COG1017	nitric oxide dioxygenase activity
D5082_RS05150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D5082_RS05165	COG2259	Doxx family
D5082_RS05170	COG1940	carbohydrate kinase activity
D5082_RS05175	COG0457	Tetratricopeptide repeat
D5082_RS05180	COG2814	Major facilitator Superfamily
D5082_RS05180	COG0477	Major facilitator Superfamily
D5082_RS05185	COG2017	converts alpha-aldose to the beta-anomer
D5082_RS05190	COG2814	Major facilitator Superfamily
D5082_RS05195	COG3711	transcriptional antiterminator
D5082_RS05200	COG3683	transport system, periplasmic component
D5082_RS05205	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
D5082_RS05235	COG0822	iron-sulfur transferase activity
D5082_RS05255	COG0633	Ferredoxin
D5082_RS05260	COG2975	iron-sulfur cluster assembly
D5082_RS05280	COG2897	thiosulfate sulfurtransferase activity
D5082_RS05285	COG2373	Large extracellular alpha-helical protein
D5082_RS05290	COG4953	penicillin-binding protein 1C
D5082_RS05325	COG2976	Protein conserved in bacteria
D5082_RS05445	COG0758	DNA mediated transformation
D5082_RS05445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D5082_RS05470	COG1645	bacterial-type flagellum-dependent swarming motility
D5082_RS05480	COG0517	IMP dehydrogenase activity
D5082_RS05480	COG0516	GMP reductase activity
D5082_RS05490	COG3119	arylsulfatase activity
D5082_RS05495	COG0641	radical SAM
D5082_RS05515	COG2200	EAL domain
D5082_RS05530	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D5082_RS05545	COG2723	6-phospho-beta-galactosidase activity
D5082_RS05555	COG2233	PERMEase
D5082_RS05570	COG1393	Belongs to the ArsC family
D5082_RS05575	COG4783	chaperone-mediated protein folding
D5082_RS05580	COG0628	permease
D5082_RS05585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D5082_RS05590	COG2716	regulation of RNA biosynthetic process
D5082_RS05600	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
D5082_RS05610	COG2321	neutral zinc metallopeptidase
D5082_RS05615	COG1444	tRNA N-acetyltransferase activity
D5082_RS05620	COG0400	carboxylic ester hydrolase activity
D5082_RS05635	COG1393	Belongs to the ArsC family
D5082_RS05645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5082_RS05655	COG0493	'glutamate synthase
D5082_RS05655	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D5082_RS05665	COG5342	invasion associated locus B
D5082_RS05670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D5082_RS05675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D5082_RS05685	COG4810	utilization protein
D5082_RS05775	COG0860	N-Acetylmuramoyl-L-alanine amidase
D5082_RS05795	COG2837	iron assimilation
D5082_RS05805	COG4150	thiosulfate binding
D5082_RS05810	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D5082_RS05815	COG4208	sulfate ABC transporter
D5082_RS05820	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D5082_RS05830	COG4319	ketosteroid isomerase
D5082_RS05865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D5082_RS05885	COG3530	Putative quorum-sensing-regulated virulence factor
D5082_RS05890	COG0385	Bile acid
D5082_RS05895	COG0583	DNA-binding transcription factor activity
D5082_RS05930	COG3415	Transposase
D5082_RS05935	COG3415	Transposase
D5082_RS05945	COG2200	EAL domain
D5082_RS05945	COG2199	diguanylate cyclase activity
D5082_RS05950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D5082_RS05965	COG0667	Aldo Keto reductase
D5082_RS05970	COG3961	Belongs to the TPP enzyme family
D5082_RS05985	COG3279	Response regulator of the LytR AlgR family
D5082_RS05990	COG3275	phosphorelay sensor kinase activity
D5082_RS06000	COG0436	Aminotransferase
D5082_RS06010	COG2807	transmembrane transport
D5082_RS06015	COG0590	tRNA wobble adenosine to inosine editing
D5082_RS06020	COG0583	DNA-binding transcription factor activity
D5082_RS06040	COG2116	formate transmembrane transporter activity
D5082_RS06045	COG2853	Lipoprotein
D5082_RS06055	COG3691	Protein conserved in bacteria
D5082_RS06070	COG2062	phosphohistidine phosphatase, SixA
D5082_RS06095	COG0730	response to heat
D5082_RS06100	COG3101	peptidyl-lysine hydroxylation
D5082_RS06115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D5082_RS06135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D5082_RS06145	COG0586	Pfam SNARE associated Golgi protein
D5082_RS06155	COG0285	dihydrofolate synthase activity
D5082_RS06160	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
D5082_RS06165	COG1286	toxin biosynthetic process
D5082_RS06170	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D5082_RS06175	COG0163	prenyltransferase activity
D5082_RS06195	COG4160	amino acid transport
D5082_RS06200	COG4598	ABC transporter
D5082_RS06210	COG1090	epimerase
D5082_RS06215	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D5082_RS06220	COG0625	glutathione transferase activity
D5082_RS06225	COG0625	glutathione transferase activity
D5082_RS06230	COG0622	Phosphoesterase
D5082_RS06235	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
D5082_RS06240	COG0857	belongs to the CobB CobQ family
D5082_RS06240	COG0280	phosphate acetyltransferase
D5082_RS06260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D5082_RS06265	COG0471	metal ion transport
D5082_RS06265	COG0490	domain, Protein
D5082_RS06275	COG0436	Aminotransferase
D5082_RS06280	COG0583	DNA-binding transcription factor activity
D5082_RS06335	COG0839	Belongs to the complex I subunit 6 family
D5082_RS06345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D5082_RS06350	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D5082_RS06365	COG2153	protein acetylation
D5082_RS06370	COG1169	isochorismate synthase
D5082_RS06395	COG0318	PFAM AMP-dependent synthetase and ligase
D5082_RS06405	COG5464	transposase or invertase
D5082_RS06425	COG1414	Transcriptional regulator
D5082_RS06435	COG2271	Major facilitator Superfamily
D5082_RS06445	COG0247	lactate metabolic process
D5082_RS06455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D5082_RS06460	COG2271	Major facilitator Superfamily
D5082_RS06475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D5082_RS06505	COG0784	Response regulator, receiver
D5082_RS06505	COG2205	protein histidine kinase activity
D5082_RS06515	COG2198	Histidine kinase
D5082_RS06515	COG0642	Histidine kinase
D5082_RS06530	COG2169	Transcriptional regulator
D5082_RS06530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D5082_RS06535	COG3145	DNA-N1-methyladenine dioxygenase activity
D5082_RS06540	COG4615	Cyclic peptide transporter
D5082_RS06545	COG2239	Acts as a magnesium transporter
D5082_RS06550	COG0659	secondary active sulfate transmembrane transporter activity
D5082_RS06565	COG0628	permease
D5082_RS06590	COG1349	DNA-binding transcription factor activity
D5082_RS06595	COG0494	nUDIX hydrolase
D5082_RS06615	COG1061	Type III restriction enzyme res subunit
D5082_RS06620	COG1187	pseudouridine synthase activity
D5082_RS06625	COG2814	Major facilitator Superfamily
D5082_RS06635	COG4172	Belongs to the ABC transporter superfamily
D5082_RS06640	COG4239	(ABC) transporter, permease
D5082_RS06645	COG4174	ABC transporter (Permease)
D5082_RS06650	COG4166	transmembrane transport
D5082_RS06655	COG2200	EAL domain
D5082_RS06660	COG0791	NLP P60 protein
D5082_RS06665	COG0671	phosphoesterase, PA-phosphatase related
D5082_RS06670	COG0523	cobalamin synthesis protein
D5082_RS06675	COG0246	Mannitol dehydrogenase
D5082_RS06680	COG1312	Catalyzes the dehydration of D-mannonate
D5082_RS06705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS06705	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS06710	COG1105	Belongs to the carbohydrate kinase PfkB family
D5082_RS06715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D5082_RS06715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D5082_RS06715	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
D5082_RS06725	COG2855	membrane
D5082_RS06735	COG0583	DNA-binding transcription factor activity
D5082_RS06740	COG0833	amino acid
D5082_RS06750	COG4771	TonB-dependent receptor
D5082_RS06765	COG2311	Membrane
D5082_RS06780	COG1129	ABC transporter
D5082_RS06790	COG2949	membrane
D5082_RS06805	COG1346	cytolysis
D5082_RS06815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D5082_RS06820	COG3659	wide pore channel activity
D5082_RS06835	COG2723	6-phospho-beta-galactosidase activity
D5082_RS06845	COG1538	Outer membrane efflux protein
D5082_RS06850	COG0586	Pfam SNARE associated Golgi protein
D5082_RS06860	COG1686	Belongs to the peptidase S11 family
D5082_RS06870	COG0277	FAD linked oxidase domain protein
D5082_RS06875	COG1472	Belongs to the glycosyl hydrolase 3 family
D5082_RS06880	COG1732	Glycine betaine
D5082_RS06885	COG1174	glycine betaine transport
D5082_RS06890	COG1125	glycine betaine transport
D5082_RS06895	COG1174	glycine betaine transport
D5082_RS06905	COG3275	phosphorelay sensor kinase activity
D5082_RS06915	COG4807	Protein conserved in bacteria
D5082_RS06935	COG5455	response to cobalt ion
D5082_RS06940	COG0583	DNA-binding transcription factor activity
D5082_RS06945	COG2252	PERMEase
D5082_RS06955	COG0583	DNA-binding transcription factor activity
D5082_RS06970	COG0351	phosphomethylpyrimidine kinase
D5082_RS06975	COG1830	Aldolase
D5082_RS07010	COG1070	Carbohydrate kinase
D5082_RS07020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D5082_RS07025	COG4948	Mandelate Racemase Muconate Lactonizing
D5082_RS07035	COG0601	transmembrane transport
D5082_RS07040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5082_RS07045	COG0444	Belongs to the ABC transporter superfamily
D5082_RS07050	COG4608	Belongs to the ABC transporter superfamily
D5082_RS07060	COG0826	peptidase U32
D5082_RS07065	COG0745	RESPONSE REGULATOR receiver
D5082_RS07070	COG2205	protein histidine kinase activity
D5082_RS07095	COG1301	dicarboxylic acid transport
D5082_RS07110	COG5002	protein histidine kinase activity
D5082_RS07115	COG0443	Heat shock 70 kDa protein
D5082_RS07120	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D5082_RS07135	COG2982	Protein involved in outer membrane biogenesis
D5082_RS07140	COG1253	flavin adenine dinucleotide binding
D5082_RS07315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D5082_RS07345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D5082_RS07350	COG0583	DNA-binding transcription factor activity
D5082_RS07360	COG0531	amino acid
D5082_RS07365	COG0640	Transcriptional regulator
D5082_RS07370	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D5082_RS07375	COG2925	Exonuclease
D5082_RS07390	COG3344	reverse transcriptase
D5082_RS07400	COG1289	transmembrane transporter activity
D5082_RS07420	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
D5082_RS07430	COG1942	4-Oxalocrotonate Tautomerase
D5082_RS07435	COG0583	DNA-binding transcription factor activity
D5082_RS07440	COG0095	Lipoate-protein ligase
D5082_RS07445	COG0477	Major facilitator Superfamily
D5082_RS07460	COG5001	Diguanylate cyclase
D5082_RS07460	COG3300	MHYT domain
D5082_RS07470	COG3615	Tellurite resistance protein tehB
D5082_RS07495	COG3706	GGDEF domain
D5082_RS07525	COG3621	Patatin-like phospholipase
D5082_RS07615	COG3504	Conjugal transfer protein
D5082_RS07690	COG4771	TonB-dependent receptor
D5082_RS07695	COG1021	2,3-dihydroxybenzoate-AMP ligase
D5082_RS07715	COG2226	methyltransferase
D5082_RS07715	COG3433	isochorismatase activity
D5082_RS07715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D5082_RS07730	COG1132	(ABC) transporter
D5082_RS07735	COG2814	Major facilitator Superfamily
D5082_RS07740	COG1169	isochorismate synthase
D5082_RS07745	COG0582	viral genome integration into host DNA
D5082_RS07755	COG0534	Mate efflux family protein
D5082_RS07765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D5082_RS07785	COG0604	alcohol dehydrogenase
D5082_RS07790	COG1309	transcriptional regulator
D5082_RS07795	COG0025	NhaP-type Na H and K H
D5082_RS07845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5082_RS07860	COG1418	mRNA catabolic process
D5082_RS07865	COG0270	DNA (cytosine-5-)-methyltransferase activity
D5082_RS07870	COG3727	T/G mismatch-specific endonuclease activity
D5082_RS07875	COG0697	spore germination
D5082_RS07880	COG2354	Protein conserved in bacteria
D5082_RS07910	COG0366	Alpha amylase catalytic
D5082_RS07915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5082_RS07925	COG0765	amino acid transport
D5082_RS07930	COG1126	abc transporter atp-binding protein
D5082_RS07935	COG2197	response regulator
D5082_RS07945	COG2197	response regulator
D5082_RS07980	COG3318	Belongs to the UPF0149 family
D5082_RS07980	COG3012	SEC-C Motif Domain Protein
D5082_RS07985	COG0814	amino acid
D5082_RS07995	COG1528	Iron-storage protein
D5082_RS08010	COG0477	Major facilitator Superfamily
D5082_RS08020	COG2211	Major facilitator Superfamily
D5082_RS08030	COG1528	Iron-storage protein
D5082_RS08040	COG1879	ABC-type sugar transport system periplasmic component
D5082_RS08050	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS08075	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D5082_RS08085	COG3102	Protein conserved in bacteria
D5082_RS08105	COG3788	relative of glutathione S-transferase, MAPEG superfamily
D5082_RS08110	COG1801	Protein of unknown function DUF72
D5082_RS08115	COG0582	viral genome integration into host DNA
D5082_RS08280	COG3772	lysozyme
D5082_RS08440	COG3344	reverse transcriptase
D5082_RS08455	COG1335	isochorismatase
D5082_RS08465	COG0494	nUDIX hydrolase
D5082_RS08490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D5082_RS08500	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
D5082_RS08505	COG0739	heme binding
D5082_RS08510	COG1560	Kdo2-lipid A biosynthetic process
D5082_RS08520	COG1737	Transcriptional regulator
D5082_RS08535	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D5082_RS08540	COG0129	dihydroxy-acid dehydratase activity
D5082_RS08545	COG0800	Aldolase
D5082_RS08555	COG3141	response to X-ray
D5082_RS08560	COG2979	Protein of unknown function (DUF533)
D5082_RS08565	COG1770	oligopeptidase
D5082_RS08570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D5082_RS08580	COG2372	response to copper ion
D5082_RS08585	COG1276	copper resistance
D5082_RS08600	COG2990	Protein conserved in bacteria
D5082_RS08625	COG3008	intermembrane lipid transfer
D5082_RS08630	COG2995	paraquat-inducible protein a
D5082_RS08635	COG1956	GAF domain-containing protein
D5082_RS08665	COG1414	Transcriptional regulator
D5082_RS08705	COG0768	penicillin binding
D5082_RS08710	COG2226	methyltransferase
D5082_RS08725	COG3716	PTS system mannose fructose sorbose family IID component
D5082_RS08730	COG3715	PTS system
D5082_RS08735	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS08735	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D5082_RS08740	COG1253	flavin adenine dinucleotide binding
D5082_RS08745	COG2200	EAL domain
D5082_RS08750	COG1760	l-serine dehydratase
D5082_RS08770	COG0251	oxidation-reduction process
D5082_RS08775	COG1199	ATP-dependent helicase activity
D5082_RS08795	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
D5082_RS08805	COG2894	cell division
D5082_RS08820	COG0179	Fumarylacetoacetate (FAA) hydrolase
D5082_RS08850	COG2719	SpoVR family
D5082_RS08870	COG1619	proteins homologs of microcin C7 resistance protein MccF
D5082_RS08880	COG4774	siderophore transport
D5082_RS08895	COG2308	Evidence 4 Homologs of previously reported genes of
D5082_RS08945	COG0583	DNA-binding transcription factor activity
D5082_RS08950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D5082_RS08965	COG1882	Formate acetyltransferase
D5082_RS08995	COG0583	DNA-binding transcription factor activity
D5082_RS09025	COG0583	DNA-binding transcription factor activity
D5082_RS09040	COG3122	Protein conserved in bacteria
D5082_RS09070	COG2885	chlorophyll binding
D5082_RS09090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D5082_RS09165	COG0012	GTP binding
D5082_RS09185	COG0659	secondary active sulfate transmembrane transporter activity
D5082_RS09220	COG2890	protein-(glutamine-N5) methyltransferase activity
D5082_RS09240	COG0387	Pfam Sodium calcium exchanger
D5082_RS09245	COG4572	Cation transport regulator
D5082_RS09250	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D5082_RS09260	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
D5082_RS09265	COG3707	response regulator
D5082_RS09270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5082_RS09280	COG1116	anion transmembrane transporter activity
D5082_RS09285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D5082_RS09285	COG2146	nitrite reductase [NAD(P)H] activity
D5082_RS09290	COG0243	molybdopterin cofactor binding
D5082_RS09295	COG4932	domain protein
D5082_RS09300	COG2197	response regulator
D5082_RS09305	COG3850	Histidine kinase
D5082_RS09310	COG2223	nitrite transmembrane transporter activity
D5082_RS09315	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D5082_RS09320	COG1140	nitrate reductase beta subunit
D5082_RS09325	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D5082_RS09330	COG2181	nitrate reductase activity
D5082_RS09340	COG1522	sequence-specific DNA binding
D5082_RS09385	COG0788	formyltetrahydrofolate deformylase activity
D5082_RS09395	COG1752	Esterase of the alpha-beta hydrolase superfamily
D5082_RS09400	COG0745	RESPONSE REGULATOR receiver
D5082_RS09405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D5082_RS09410	COG2916	Histone family protein nucleoid-structuring protein H-NS
D5082_RS09415	COG1435	thymidine kinase activity
D5082_RS09420	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS09420	COG1454	alcohol dehydrogenase
D5082_RS09430	COG2095	MarC family integral membrane protein
D5082_RS09435	COG4166	transmembrane transport
D5082_RS09440	COG0601	transmembrane transport
D5082_RS09445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5082_RS09450	COG0444	Belongs to the ABC transporter superfamily
D5082_RS09460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D5082_RS09480	COG2353	YceI-like domain
D5082_RS09485	COG2350	Protein conserved in bacteria
D5082_RS09495	COG3001	Fructosamine kinase
D5082_RS09505	COG1105	Belongs to the carbohydrate kinase PfkB family
D5082_RS09510	COG3137	Salt-induced outer membrane protein
D5082_RS09550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D5082_RS09550	COG0072	phenylalanine-tRNA ligase activity
D5082_RS09570	COG0583	DNA-binding transcription factor activity
D5082_RS09590	COG0386	Belongs to the glutathione peroxidase family
D5082_RS09600	COG0791	NLP P60 protein
D5082_RS09610	COG4256	Hemin uptake protein
D5082_RS09615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D5082_RS09625	COG0574	Belongs to the PEP-utilizing enzyme family
D5082_RS09625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D5082_RS09635	COG0628	permease
D5082_RS09640	COG0277	FAD linked oxidase domain protein
D5082_RS09640	COG0247	lactate metabolic process
D5082_RS09645	COG2050	protein possibly involved in aromatic compounds catabolism
D5082_RS09650	COG2261	transglycosylase associated protein
D5082_RS09680	COG1120	ATPase activity
D5082_RS09685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D5082_RS09695	COG0583	DNA-binding transcription factor activity
D5082_RS09720	COG1304	FMN binding
D5082_RS09725	COG1309	transcriptional regulator
D5082_RS09740	COG0316	Belongs to the HesB IscA family
D5082_RS09745	COG0719	Fe-S assembly protein
D5082_RS09750	COG0396	ATPase activity
D5082_RS09755	COG0719	Fe-S assembly protein
D5082_RS09770	COG1376	ErfK ybiS ycfS ynhG family protein
D5082_RS09795	COG1309	transcriptional regulator
D5082_RS09800	COG3185	4-Hydroxyphenylpyruvate dioxygenase
D5082_RS09800	COG1082	Xylose isomerase domain protein TIM barrel
D5082_RS09805	COG2271	Major facilitator Superfamily
D5082_RS09810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D5082_RS09820	COG1120	ATPase activity
D5082_RS09825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D5082_RS09830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D5082_RS09835	COG1414	Transcriptional regulator
D5082_RS09870	COG2814	Major facilitator Superfamily
D5082_RS09890	COG0583	DNA-binding transcription factor activity
D5082_RS09895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5082_RS09915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5082_RS09920	COG1116	anion transmembrane transporter activity
D5082_RS09925	COG4774	siderophore transport
D5082_RS09930	COG1120	ATPase activity
D5082_RS09935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D5082_RS09940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D5082_RS09960	COG0765	amino acid transport
D5082_RS09965	COG1126	abc transporter atp-binding protein
D5082_RS09995	COG1473	amidohydrolase
D5082_RS10000	COG3383	formate dehydrogenase (NAD+) activity
D5082_RS10005	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D5082_RS10020	COG1175	transmembrane transport
D5082_RS10055	COG1857	crispr-associated protein
D5082_RS10065	COG1518	maintenance of DNA repeat elements
D5082_RS10070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D5082_RS10080	COG3157	Type VI secretion system effector, Hcp
D5082_RS10110	COG4133	protoheme IX ABC transporter activity
D5082_RS10115	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D5082_RS10120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D5082_RS10135	COG1138	Cytochrome C-type biogenesis protein
D5082_RS10140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D5082_RS10145	COG3088	subunit of a heme lyase
D5082_RS10145	COG4235	cytochrome complex assembly
D5082_RS10195	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS10200	COG2610	gluconate transmembrane transporter activity
D5082_RS10205	COG1250	3-hydroxyacyl-CoA dehydrogenase
D5082_RS10215	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D5082_RS10225	COG0583	DNA-binding transcription factor activity
D5082_RS10245	COG0277	FAD linked oxidase domain protein
D5082_RS10250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5082_RS10275	COG0402	S-adenosylhomocysteine deaminase activity
D5082_RS10400	COG2814	Major facilitator Superfamily
D5082_RS10405	COG1082	Xylose isomerase domain protein TIM barrel
D5082_RS10435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5082_RS10465	COG4608	Belongs to the ABC transporter superfamily
D5082_RS10470	COG0444	Belongs to the ABC transporter superfamily
D5082_RS10495	COG0346	lactoylglutathione lyase activity
D5082_RS10500	COG1349	DNA-binding transcription factor activity
D5082_RS10530	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D5082_RS10550	COG0300	oxidoreductase activity
D5082_RS10595	COG0307	riboflavin synthase, alpha
D5082_RS10600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D5082_RS10605	COG2814	Major facilitator Superfamily
D5082_RS10610	COG0583	DNA-binding transcription factor activity
D5082_RS10625	COG2814	Major facilitator Superfamily
D5082_RS10640	COG0791	NLP P60 protein
D5082_RS10645	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D5082_RS10655	COG0346	lactoylglutathione lyase activity
D5082_RS10660	COG1902	pentaerythritol trinitrate reductase activity
D5082_RS10665	COG1309	transcriptional regulator
D5082_RS10670	COG3313	Fe-S protein
D5082_RS10675	COG4989	oxidoreductase activity
D5082_RS10680	COG2032	superoxide dismutase activity
D5082_RS10685	COG1289	transmembrane transporter activity
D5082_RS10690	COG1566	PFAM secretion protein HlyD family protein
D5082_RS10720	COG3895	Periplasmic Protein
D5082_RS10735	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
D5082_RS10740	COG0625	glutathione transferase activity
D5082_RS10755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D5082_RS10765	COG4659	FMN binding
D5082_RS10800	COG2723	6-phospho-beta-galactosidase activity
D5082_RS10810	COG0673	inositol 2-dehydrogenase activity
D5082_RS10820	COG2814	Major facilitator Superfamily
D5082_RS10840	COG3038	cytochrome b561
D5082_RS10860	COG0583	DNA-binding transcription factor activity
D5082_RS10865	COG3485	protocatechuate 3,4-dioxygenase
D5082_RS10870	COG3485	protocatechuate 3,4-dioxygenase
D5082_RS10875	COG5383	Protein conserved in bacteria
D5082_RS10880	COG2272	Belongs to the type-B carboxylesterase lipase family
D5082_RS10895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D5082_RS10900	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D5082_RS10905	COG1275	C4-dicarboxylate transporter malic acid transport protein
D5082_RS10910	COG0500	methyltransferase
D5082_RS10920	COG0697	spore germination
D5082_RS10925	COG2207	Transcriptional regulator
D5082_RS10925	COG3708	Transcriptional regulator
D5082_RS10930	COG3135	benzoate transporter
D5082_RS10935	COG1396	sequence-specific DNA binding
D5082_RS10945	COG0826	peptidase U32
D5082_RS10965	COG1294	oxidase, subunit
D5082_RS10970	COG1271	oxidase subunit
D5082_RS10975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5082_RS10980	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D5082_RS10985	COG3842	ATPase activity
D5082_RS10990	COG1176	ABC-type spermidine putrescine transport system, permease component I
D5082_RS10995	COG1177	transmembrane transport
D5082_RS11000	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS11030	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS11035	COG0747	negative chemotaxis
D5082_RS11045	COG3238	Protein conserved in bacteria
D5082_RS11050	COG1247	-acetyltransferase
D5082_RS11060	COG2130	NADP-dependent
D5082_RS11075	COG3691	Protein conserved in bacteria
D5082_RS11080	COG1228	amidohydrolase
D5082_RS11085	COG4772	TonB-dependent receptor
D5082_RS11110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D5082_RS11120	COG1473	amidohydrolase
D5082_RS11125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5082_RS11130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5082_RS11140	COG0765	amino acid transport
D5082_RS11145	COG1126	abc transporter atp-binding protein
D5082_RS11155	COG0625	glutathione transferase activity
D5082_RS11185	COG2211	Major facilitator Superfamily
D5082_RS11200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D5082_RS11205	COG3842	ATPase activity
D5082_RS11210	COG1840	ABC-type Fe3 transport system, periplasmic component
D5082_RS11215	COG1178	ABC-type Fe3 transport system permease component
D5082_RS11220	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D5082_RS11225	COG2181	nitrate reductase activity
D5082_RS11230	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D5082_RS11235	COG1140	nitrate reductase beta subunit
D5082_RS11240	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D5082_RS11260	COG1414	Transcriptional regulator
D5082_RS11265	COG4948	Mandelate Racemase Muconate Lactonizing
D5082_RS11270	COG4829	muconolactone delta-isomerase
D5082_RS11275	COG3485	protocatechuate 3,4-dioxygenase
D5082_RS11285	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
D5082_RS11305	COG3383	formate dehydrogenase (NAD+) activity
D5082_RS11305	COG0243	molybdopterin cofactor binding
D5082_RS11310	COG0243	molybdopterin cofactor binding
D5082_RS11310	COG3383	formate dehydrogenase (NAD+) activity
D5082_RS11315	COG0437	4 iron, 4 sulfur cluster binding
D5082_RS11320	COG2864	formate dehydrogenase
D5082_RS11335	COG2326	polyphosphate kinase activity
D5082_RS11345	COG2814	Major facilitator Superfamily
D5082_RS11355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5082_RS11365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5082_RS11375	COG0747	negative chemotaxis
D5082_RS11380	COG1064	alcohol dehydrogenase
D5082_RS11395	COG0488	(ABC) transporter
D5082_RS11430	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS11435	COG3729	General stress protein
D5082_RS11455	COG3685	Protein conserved in bacteria
D5082_RS11465	COG0366	Alpha amylase catalytic
D5082_RS11475	COG2323	membrane
D5082_RS11485	COG3111	PFAM Bacterial OB fold (BOF) protein
D5082_RS11490	COG1764	response to oxidative stress
D5082_RS11515	COG3781	membrane
D5082_RS11520	COG0243	molybdopterin cofactor binding
D5082_RS11525	COG0583	DNA-binding transcription factor activity
D5082_RS11530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS11555	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS11560	COG1447	Phosphotransferase system cellobiose-specific component IIA
D5082_RS11565	COG2814	Major facilitator Superfamily
D5082_RS11575	COG1285	pathogenesis
D5082_RS11580	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D5082_RS11600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D5082_RS11600	COG0519	Catalyzes the synthesis of GMP from XMP
D5082_RS11640	COG0596	Alpha beta hydrolase
D5082_RS11650	COG2205	protein histidine kinase activity
D5082_RS11665	COG0076	glutamate decarboxylase activity
D5082_RS11670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D5082_RS11675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5082_RS11680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5082_RS11685	COG1116	anion transmembrane transporter activity
D5082_RS11690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D5082_RS11705	COG0673	inositol 2-dehydrogenase activity
D5082_RS11715	COG1609	Transcriptional regulator
D5082_RS11720	COG3706	GGDEF domain
D5082_RS11725	COG0402	S-adenosylhomocysteine deaminase activity
D5082_RS11730	COG1953	Uracil, thiamine, allantoin
D5082_RS11765	COG0596	Alpha beta hydrolase
D5082_RS11780	COG2207	Transcriptional regulator
D5082_RS11795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D5082_RS11815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D5082_RS11860	COG0765	amino acid transport
D5082_RS11870	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D5082_RS11880	COG2070	2-Nitropropane dioxygenase
D5082_RS11885	COG0583	DNA-binding transcription factor activity
D5082_RS11895	COG1902	pentaerythritol trinitrate reductase activity
D5082_RS11900	COG4529	Protein conserved in bacteria
D5082_RS11905	COG0477	Major facilitator Superfamily
D5082_RS11935	COG2223	nitrite transmembrane transporter activity
D5082_RS11945	COG1609	Transcriptional regulator
D5082_RS11950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS11960	COG3037	sugar-specific permease SgaT UlaA
D5082_RS11965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D5082_RS11975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D5082_RS11980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D5082_RS11980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D5082_RS11980	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
D5082_RS11995	COG0583	DNA-binding transcription factor activity
D5082_RS12000	COG0583	DNA-binding transcription factor activity
D5082_RS12005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D5082_RS12015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D5082_RS12030	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS12040	COG1609	Transcriptional regulator
D5082_RS12070	COG1652	LysM domain
D5082_RS12100	COG0456	acetyltransferase
D5082_RS12100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D5082_RS12110	COG0667	Aldo Keto reductase
D5082_RS12115	COG0667	Aldo Keto reductase
D5082_RS12120	COG3386	PFAM SMP-30 Gluconolaconase
D5082_RS12125	COG0667	Aldo Keto reductase
D5082_RS12155	COG0251	oxidation-reduction process
D5082_RS12160	COG0583	DNA-binding transcription factor activity
D5082_RS12165	COG0626	cystathionine gamma-synthase activity
D5082_RS12170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5082_RS12175	COG0814	amino acid
D5082_RS12180	COG0583	DNA-binding transcription factor activity
D5082_RS12190	COG1294	oxidase, subunit
D5082_RS12195	COG1271	oxidase subunit
D5082_RS12205	COG3118	belongs to the thioredoxin family
D5082_RS12235	COG0583	DNA-binding transcription factor activity
D5082_RS12275	COG1929	Belongs to the glycerate kinase type-1 family
D5082_RS12280	COG3835	regulator
D5082_RS12290	COG0583	DNA-binding transcription factor activity
D5082_RS12300	COG2186	Transcriptional regulator
D5082_RS12305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D5082_RS12305	COG1263	PTS System
D5082_RS12315	COG2814	Major facilitator Superfamily
D5082_RS12320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS12320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS12340	COG2819	hydrolase of the alpha beta superfamily
D5082_RS12345	COG5001	Diguanylate cyclase
D5082_RS12345	COG3300	MHYT domain
D5082_RS12380	COG3188	usher protein
D5082_RS12395	COG1649	PFAM Uncharacterised BCR, COG1649
D5082_RS12400	COG3550	peptidyl-serine autophosphorylation
D5082_RS12405	COG1396	sequence-specific DNA binding
D5082_RS12410	COG2351	hydroxyisourate hydrolase activity
D5082_RS12415	COG3648	Uricase
D5082_RS12415	COG3195	allantoin biosynthetic process
D5082_RS12420	COG2233	PERMEase
D5082_RS12450	COG2207	Transcriptional regulator
D5082_RS12465	COG4628	conserved protein (DUF2132)
D5082_RS12485	COG2011	ABC-type metal ion transport system permease component
D5082_RS12490	COG2070	2-Nitropropane dioxygenase
D5082_RS12500	COG0477	Major facilitator Superfamily
D5082_RS12575	COG2199	diguanylate cyclase activity
D5082_RS12590	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS12595	COG0583	DNA-binding transcription factor activity
D5082_RS12605	COG0039	L-malate dehydrogenase activity
D5082_RS12610	COG1349	DNA-binding transcription factor activity
D5082_RS12615	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D5082_RS12620	COG3395	kinase activity
D5082_RS12630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D5082_RS12635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D5082_RS12640	COG2271	Major facilitator Superfamily
D5082_RS12665	COG4977	sequence-specific DNA binding
D5082_RS12675	COG0697	spore germination
D5082_RS12680	COG2814	Major facilitator Superfamily
D5082_RS12695	COG1129	ABC transporter
D5082_RS12710	COG0683	leucine binding
D5082_RS12715	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D5082_RS12750	COG2223	nitrite transmembrane transporter activity
D5082_RS12755	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D5082_RS12770	COG1349	DNA-binding transcription factor activity
D5082_RS12775	COG2084	Dehydrogenase
D5082_RS12780	COG3395	kinase activity
D5082_RS12785	COG0235	Class ii aldolase
D5082_RS12790	COG3622	Belongs to the hyi family
D5082_RS12795	COG2610	gluconate transmembrane transporter activity
D5082_RS12800	COG3708	Transcriptional regulator
D5082_RS12800	COG2207	Transcriptional regulator
D5082_RS12820	COG2200	EAL domain
D5082_RS12825	COG1546	Belongs to the CinA family
D5082_RS12830	COG0071	Belongs to the small heat shock protein (HSP20) family
D5082_RS12845	COG2197	response regulator
D5082_RS12850	COG2135	peptidase activity
D5082_RS12855	COG2207	Transcriptional regulator
D5082_RS12870	COG4221	oxidoreductase activity
D5082_RS12875	COG1802	Transcriptional regulator
D5082_RS12880	COG0589	response to stress
D5082_RS12885	COG0246	Mannitol dehydrogenase
D5082_RS12890	COG2271	Major facilitator Superfamily
D5082_RS12905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D5082_RS12920	COG0243	molybdopterin cofactor binding
D5082_RS12925	COG0437	4 iron, 4 sulfur cluster binding
D5082_RS12930	COG3302	dmso reductase anchor subunit
D5082_RS12945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D5082_RS12950	COG1940	carbohydrate kinase activity
D5082_RS12955	COG0583	DNA-binding transcription factor activity
D5082_RS12960	COG2814	Major facilitator Superfamily
D5082_RS12965	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D5082_RS12975	COG3591	Belongs to the peptidase S1B family
D5082_RS12995	COG0628	permease
D5082_RS13025	COG0679	Auxin Efflux Carrier
D5082_RS13035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D5082_RS13060	COG3290	protein histidine kinase activity
D5082_RS13065	COG4565	transcriptional regulatory protein
D5082_RS13090	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D5082_RS13090	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D5082_RS13110	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D5082_RS13115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D5082_RS13125	COG0183	Belongs to the thiolase family
D5082_RS13130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D5082_RS13140	COG1414	Transcriptional regulator
D5082_RS13145	COG2840	Smr protein MutS2
D5082_RS13150	COG0583	DNA-binding transcription factor activity
D5082_RS13160	COG1473	amidohydrolase
D5082_RS13165	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D5082_RS13180	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D5082_RS13285	COG1802	Transcriptional regulator
D5082_RS13285	COG4626	Terminase
D5082_RS13350	COG1403	HNH endonuclease
D5082_RS13355	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D5082_RS13365	COG1846	Transcriptional regulator
D5082_RS13445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D5082_RS13460	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
D5082_RS13465	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
D5082_RS13485	COG0531	amino acid
D5082_RS13495	COG3136	membrane protein required for alginate biosynthesis
D5082_RS13500	COG0745	RESPONSE REGULATOR receiver
D5082_RS13510	COG2205	protein histidine kinase activity
D5082_RS13520	COG0114	fumarate hydratase activity
D5082_RS13525	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D5082_RS13525	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D5082_RS13530	COG1482	cell wall glycoprotein biosynthetic process
D5082_RS13535	COG5339	Protein conserved in bacteria
D5082_RS13540	COG1609	Transcriptional regulator
D5082_RS13545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D5082_RS13545	COG1263	PTS System
D5082_RS13550	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D5082_RS13575	COG2391	methyltransferase activity
D5082_RS13580	COG0425	Belongs to the sulfur carrier protein TusA family
D5082_RS13585	COG5562	phage envelope protein
D5082_RS13590	COG0401	homolog of Blt101
D5082_RS13595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D5082_RS13600	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS13605	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D5082_RS13610	COG0477	Major facilitator Superfamily
D5082_RS13615	COG1113	amino acid transport
D5082_RS13620	COG2988	succinylglutamate desuccinylase activity
D5082_RS13625	COG3724	N-succinylarginine dihydrolase activity
D5082_RS13630	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS13635	COG3138	arginine N-succinyltransferase
D5082_RS13640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D5082_RS13645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D5082_RS13650	COG0667	Aldo Keto reductase
D5082_RS13655	COG0583	DNA-binding transcription factor activity
D5082_RS13680	COG4122	O-methyltransferase activity
D5082_RS13685	COG1643	Atp-dependent helicase
D5082_RS13700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D5082_RS13705	COG3327	negative regulation of DNA-templated transcription, initiation
D5082_RS13710	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
D5082_RS13715	COG0183	Belongs to the thiolase family
D5082_RS13720	COG2050	protein possibly involved in aromatic compounds catabolism
D5082_RS13725	COG1250	3-hydroxyacyl-CoA dehydrogenase
D5082_RS13730	COG1024	Enoyl-CoA hydratase
D5082_RS13735	COG1024	Enoyl-CoA hydratase
D5082_RS13740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D5082_RS13745	COG2151	metal-sulfur cluster biosynthetic enzyme
D5082_RS13750	COG3396	Phenylacetate-CoA oxygenase
D5082_RS13755	COG3460	Phenylacetate-CoA oxygenase
D5082_RS13760	COG3396	Phenylacetate-CoA oxygenase
D5082_RS13765	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS13765	COG2030	dehydratase
D5082_RS13790	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS13795	COG2207	Transcriptional regulator
D5082_RS13800	COG3784	Protein of unknown function (DUF1318)
D5082_RS13810	COG2911	Protein conserved in bacteria
D5082_RS13815	COG0586	Pfam SNARE associated Golgi protein
D5082_RS13820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D5082_RS13825	COG3187	Heat shock protein
D5082_RS13830	COG3042	response to heat
D5082_RS13840	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
D5082_RS13840	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D5082_RS13840	COG0674	pyruvate-flavodoxin oxidoreductase activity
D5082_RS13840	COG1013	pyruvate-flavodoxin oxidoreductase activity
D5082_RS13845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5082_RS13855	COG0589	response to stress
D5082_RS13865	COG0513	Belongs to the DEAD box helicase family
D5082_RS13890	COG1349	DNA-binding transcription factor activity
D5082_RS13895	COG0673	inositol 2-dehydrogenase activity
D5082_RS13910	COG1113	amino acid transport
D5082_RS13915	COG1522	sequence-specific DNA binding
D5082_RS13925	COG1448	Aminotransferase
D5082_RS13930	COG2011	ABC-type metal ion transport system permease component
D5082_RS13940	COG1464	Belongs to the NlpA lipoprotein family
D5082_RS13945	COG0436	Aminotransferase
D5082_RS13950	COG0604	alcohol dehydrogenase
D5082_RS13975	COG0583	DNA-binding transcription factor activity
D5082_RS13995	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS14000	COG1309	transcriptional regulator
D5082_RS14005	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS14120	COG2885	chlorophyll binding
D5082_RS14145	COG0693	protein deglycase activity
D5082_RS14150	COG1078	dGTPase activity
D5082_RS14155	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS14160	COG0583	DNA-binding transcription factor activity
D5082_RS14230	COG5002	protein histidine kinase activity
D5082_RS14230	COG2205	protein histidine kinase activity
D5082_RS14230	COG0784	Response regulator, receiver
D5082_RS14235	COG3250	beta-galactosidase activity
D5082_RS14240	COG0656	L-ascorbic acid biosynthetic process
D5082_RS14270	COG4166	transmembrane transport
D5082_RS14275	COG2866	Carboxypeptidase
D5082_RS14280	COG4948	Mandelate Racemase Muconate Lactonizing
D5082_RS14285	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D5082_RS14290	COG3180	Ammonia monooxygenase
D5082_RS14300	COG1486	melibiose metabolic process
D5082_RS14305	COG0583	DNA-binding transcription factor activity
D5082_RS14315	COG3106	COG3106 Predicted ATPase
D5082_RS14325	COG1983	PspC domain protein
D5082_RS14335	COG1842	Phage shock protein A
D5082_RS14340	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D5082_RS14350	COG1473	amidohydrolase
D5082_RS14365	COG0702	epimerase
D5082_RS14380	COG4171	peptide transport system, permease
D5082_RS14395	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D5082_RS14405	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D5082_RS14410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D5082_RS14410	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D5082_RS14425	COG1349	DNA-binding transcription factor activity
D5082_RS14435	COG0023	Translation Initiation Factor
D5082_RS14445	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D5082_RS14450	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
D5082_RS14455	COG0671	phosphoesterase, PA-phosphatase related
D5082_RS14465	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D5082_RS14495	COG0616	signal peptide processing
D5082_RS14505	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS14510	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
D5082_RS14540	COG0583	DNA-binding transcription factor activity
D5082_RS14550	COG0009	L-threonylcarbamoyladenylate synthase
D5082_RS14560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D5082_RS14565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D5082_RS14565	COG0512	Glutamine amidotransferase of anthranilate synthase
D5082_RS14570	COG0135	phosphoribosylanthranilate isomerase activity
D5082_RS14570	COG0134	indole-3-glycerol-phosphate synthase activity
D5082_RS14625	COG4774	siderophore transport
D5082_RS14635	COG3047	cAMP biosynthetic process
D5082_RS14640	COG0727	PFAM Uncharacterised protein family (UPF0153)
D5082_RS14670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D5082_RS14675	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS14680	COG1988	membrane-bound metal-dependent
D5082_RS14685	COG1823	symporter activity
D5082_RS14695	COG0753	catalase activity
D5082_RS14705	COG1486	melibiose metabolic process
D5082_RS14710	COG2169	Transcriptional regulator
D5082_RS14710	COG1917	Cupin 2, conserved barrel domain protein
D5082_RS14715	COG1447	Phosphotransferase system cellobiose-specific component IIA
D5082_RS14720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS14725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS14730	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D5082_RS14740	COG0322	excinuclease ABC activity
D5082_RS14745	COG3678	ATP-independent chaperone mediated protein folding
D5082_RS14755	COG3724	N-succinylarginine dihydrolase activity
D5082_RS14765	COG3138	arginine N-succinyltransferase
D5082_RS14775	COG0708	Exodeoxyribonuclease III
D5082_RS14780	COG0398	Pfam SNARE associated Golgi protein
D5082_RS14785	COG0398	Pfam SNARE associated Golgi protein
D5082_RS14790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D5082_RS14795	COG4134	Bacterial extracellular solute-binding protein
D5082_RS14800	COG4135	transport system, permease component
D5082_RS14805	COG4136	ATPase activity
D5082_RS14810	COG2897	thiosulfate sulfurtransferase activity
D5082_RS14815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D5082_RS14820	COG0494	nUDIX hydrolase
D5082_RS14825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D5082_RS14830	COG3321	synthase
D5082_RS14830	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS14830	COG0604	alcohol dehydrogenase
D5082_RS14835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D5082_RS14840	COG0709	Synthesizes selenophosphate from selenide and ATP
D5082_RS14860	COG0778	Nitroreductase
D5082_RS14865	COG0616	signal peptide processing
D5082_RS14870	COG0252	asparaginase activity
D5082_RS14875	COG1335	isochorismatase
D5082_RS14890	COG3139	Protein of unknown function (DUF1315)
D5082_RS14910	COG0656	L-ascorbic acid biosynthetic process
D5082_RS14915	COG3713	MltA-interacting MipA family protein
D5082_RS14920	COG2766	serine protein kinase
D5082_RS14935	COG0386	Belongs to the glutathione peroxidase family
D5082_RS14955	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS14960	COG0583	DNA-binding transcription factor activity
D5082_RS14965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D5082_RS14970	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D5082_RS14975	COG3344	reverse transcriptase
D5082_RS14990	COG0859	PFAM glycosyl transferase family 9
D5082_RS14995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D5082_RS15005	COG2207	Transcriptional regulator
D5082_RS15010	COG2807	transmembrane transport
D5082_RS15015	COG0504	CTP synthase activity
D5082_RS15020	COG1683	Conserved Protein
D5082_RS15025	COG3189	MarR family transcriptional regulator
D5082_RS15030	COG3042	response to heat
D5082_RS15165	COG4695	Portal protein
D5082_RS15185	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D5082_RS15230	COG4974	Belongs to the 'phage' integrase family
D5082_RS15235	COG2199	diguanylate cyclase activity
D5082_RS15235	COG2203	Gaf domain
D5082_RS15255	COG3182	Iron-regulated membrane protein
D5082_RS15265	COG1560	Kdo2-lipid A biosynthetic process
D5082_RS15280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D5082_RS15285	COG3706	GGDEF domain
D5082_RS15295	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D5082_RS15320	COG1294	oxidase, subunit
D5082_RS15325	COG1271	oxidase subunit
D5082_RS15330	COG3546	catalase activity
D5082_RS15335	COG3685	Protein conserved in bacteria
D5082_RS15340	COG3685	Protein conserved in bacteria
D5082_RS15345	COG3729	General stress protein
D5082_RS15350	COG1063	alcohol dehydrogenase
D5082_RS15355	COG3813	Protein conserved in bacteria
D5082_RS15375	COG0640	Transcriptional regulator
D5082_RS15380	COG0538	isocitrate dehydrogenase activity
D5082_RS15385	COG1187	pseudouridine synthase activity
D5082_RS15405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D5082_RS15425	COG2205	protein histidine kinase activity
D5082_RS15430	COG2850	peptidyl-arginine hydroxylation
D5082_RS15450	COG1177	transmembrane transport
D5082_RS15465	COG0318	PFAM AMP-dependent synthetase and ligase
D5082_RS15470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D5082_RS15475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D5082_RS15480	COG0698	ribose 5-phosphate isomerase
D5082_RS15495	COG3395	kinase activity
D5082_RS15510	COG2390	Transcriptional regulator
D5082_RS15520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D5082_RS15530	COG4591	ABC-type transport system involved in lipoprotein release permease component
D5082_RS15540	COG4591	ABC-type transport system involved in lipoprotein release permease component
D5082_RS15545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D5082_RS15550	COG1376	ErfK ybiS ycfS ynhG family protein
D5082_RS15550	COG1388	LysM domain
D5082_RS15560	COG1309	transcriptional regulator
D5082_RS15570	COG3134	Outer membrane lipoprotein
D5082_RS15575	COG1252	NADH dehydrogenase
D5082_RS15600	COG5633	Lipoprotein
D5082_RS15605	COG0537	adenosine 5'-monophosphoramidase activity
D5082_RS15615	COG0084	hydrolase, TatD family'
D5082_RS15620	COG0470	DNA polymerase III
D5082_RS15630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D5082_RS15635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D5082_RS15640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D5082_RS15655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D5082_RS15675	COG1399	metal-binding, possibly nucleic acid-binding protein
D5082_RS15695	COG1530	ribonuclease E activity
D5082_RS15700	COG0583	DNA-binding transcription factor activity
D5082_RS15705	COG2814	Major facilitator Superfamily
D5082_RS15725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D5082_RS15775	COG1560	Kdo2-lipid A biosynthetic process
D5082_RS15795	COG5645	(Lipo)protein
D5082_RS15835	COG3381	protein complex oligomerization
D5082_RS15860	COG0583	DNA-binding transcription factor activity
D5082_RS15870	COG1335	isochorismatase
D5082_RS15880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D5082_RS15885	COG1702	phosphate starvation-inducible protein PhoH
D5082_RS15905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D5082_RS15915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D5082_RS15935	COG1309	transcriptional regulator
D5082_RS15970	COG2233	PERMEase
D5082_RS15980	COG3729	General stress protein
D5082_RS16005	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS16020	COG0531	amino acid
D5082_RS16030	COG0174	glutamine synthetase
D5082_RS16035	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D5082_RS16040	COG1917	Cupin 2, conserved barrel domain protein
D5082_RS16040	COG1396	sequence-specific DNA binding
D5082_RS16045	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS16050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5082_RS16055	COG0583	DNA-binding transcription factor activity
D5082_RS16060	COG0473	3-isopropylmalate dehydrogenase activity
D5082_RS16070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D5082_RS16075	COG4638	Rieske (2fe-2S)
D5082_RS16080	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS16085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D5082_RS16090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D5082_RS16090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS16090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS16095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D5082_RS16100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D5082_RS16105	COG1882	Formate acetyltransferase
D5082_RS16110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D5082_RS16115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D5082_RS16125	COG2207	Transcriptional regulator
D5082_RS16130	COG3706	GGDEF domain
D5082_RS16150	COG2200	EAL domain
D5082_RS16160	COG0058	SHG alpha-glucan phosphorylase activity
D5082_RS16175	COG0670	Belongs to the BI1 family
D5082_RS16190	COG2207	Transcriptional regulator
D5082_RS16195	COG1881	PFAM PEBP family protein
D5082_RS16220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5082_RS16225	COG2274	protein secretion by the type I secretion system
D5082_RS16240	COG1832	CoA-binding protein
D5082_RS16250	COG0210	DNA helicase
D5082_RS16255	COG3304	Inner membrane component domain
D5082_RS16260	COG1289	transmembrane transporter activity
D5082_RS16265	COG3070	regulator of competence-specific genes
D5082_RS16290	COG1067	ATP-dependent peptidase activity
D5082_RS16300	COG3130	regulation of translation
D5082_RS16310	COG3009	Protein conserved in bacteria
D5082_RS16315	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D5082_RS16315	COG3008	intermembrane lipid transfer
D5082_RS16320	COG2995	paraquat-inducible protein a
D5082_RS16335	COG0633	Ferredoxin
D5082_RS16335	COG3217	Mosc domain protein beta barrel domain protein
D5082_RS16350	COG0431	NADPH-dependent FMN reductase
D5082_RS16355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D5082_RS16360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D5082_RS16365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5082_RS16375	COG0308	aminopeptidase N
D5082_RS16390	COG1473	amidohydrolase
D5082_RS16400	COG0814	amino acid
D5082_RS16410	COG1522	sequence-specific DNA binding
D5082_RS16420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D5082_RS16425	COG1448	Aminotransferase
D5082_RS16430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D5082_RS16435	COG3108	Peptidase M15
D5082_RS16445	COG2989	Protein conserved in bacteria
D5082_RS16455	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
D5082_RS16465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D5082_RS16470	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D5082_RS16475	COG3173	Aminoglycoside phosphotransferase
D5082_RS16490	COG3214	Protein conserved in bacteria
D5082_RS16505	COG2333	competence protein COMEC
D5082_RS16505	COG0658	competence protein
D5082_RS16515	COG0539	negative regulation of cytoplasmic translation
D5082_RS16535	COG2323	membrane
D5082_RS16540	COG1944	ATP diphosphatase activity
D5082_RS16545	COG2116	formate transmembrane transporter activity
D5082_RS16550	COG1882	Formate acetyltransferase
D5082_RS16555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D5082_RS16560	COG0477	Major facilitator Superfamily
D5082_RS16570	COG3302	dmso reductase anchor subunit
D5082_RS16575	COG0437	4 iron, 4 sulfur cluster binding
D5082_RS16580	COG0243	molybdopterin cofactor binding
D5082_RS16590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D5082_RS16600	COG1178	ABC-type Fe3 transport system permease component
D5082_RS16600	COG1674	ftsk spoiiie
D5082_RS16610	COG0492	ferredoxin-NADP+ reductase activity
D5082_RS16615	COG4988	ABC transporter
D5082_RS16620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D5082_RS16635	COG0542	response to heat
D5082_RS16645	COG1278	Cold shock
D5082_RS16660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5082_RS16665	COG3593	DNA synthesis involved in DNA repair
D5082_RS16675	COG2431	L-lysine efflux transmembrane transporter activity
D5082_RS16685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D5082_RS16700	COG0028	Belongs to the TPP enzyme family
D5082_RS16705	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
D5082_RS16710	COG0702	epimerase
D5082_RS16715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D5082_RS16720	COG3023	N-Acetylmuramoyl-L-alanine amidase
D5082_RS16725	COG4251	negative regulation of phosphorylation
D5082_RS16725	COG5001	Diguanylate cyclase
D5082_RS16725	COG3706	GGDEF domain
D5082_RS16725	COG2203	Gaf domain
D5082_RS16740	COG1126	abc transporter atp-binding protein
D5082_RS16745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5082_RS16750	COG4215	(ABC) transporter
D5082_RS16755	COG4160	amino acid transport
D5082_RS16760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5082_RS16765	COG5002	protein histidine kinase activity
D5082_RS16770	COG0745	RESPONSE REGULATOR receiver
D5082_RS16785	COG1177	transmembrane transport
D5082_RS16790	COG1176	ABC-type spermidine putrescine transport system, permease component I
D5082_RS16795	COG3842	ATPase activity
D5082_RS16800	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D5082_RS16815	COG0778	Nitroreductase
D5082_RS16840	COG3226	Transcriptional regulator
D5082_RS16845	COG0738	Major facilitator superfamily
D5082_RS16850	COG0561	phosphatase activity
D5082_RS16855	COG2814	Major facilitator Superfamily
D5082_RS16865	COG0671	phosphoesterase, PA-phosphatase related
D5082_RS16870	COG1349	DNA-binding transcription factor activity
D5082_RS16875	COG1686	Belongs to the peptidase S11 family
D5082_RS16880	COG0625	glutathione transferase activity
D5082_RS16885	COG2133	pyrroloquinoline quinone binding
D5082_RS16895	COG2223	nitrite transmembrane transporter activity
D5082_RS16920	COG0747	negative chemotaxis
D5082_RS16935	COG0303	'Molybdopterin
D5082_RS16940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D5082_RS16945	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D5082_RS16950	COG1882	Formate acetyltransferase
D5082_RS16955	COG0561	phosphatase activity
D5082_RS16965	COG1609	Transcriptional regulator
D5082_RS16970	COG2271	Major facilitator Superfamily
D5082_RS16985	COG0488	(ABC) transporter
D5082_RS16990	COG2365	Tyrosine phosphatase family
D5082_RS16995	COG1376	ErfK ybiS ycfS ynhG family protein
D5082_RS17000	COG2188	Transcriptional regulator
D5082_RS17005	COG2723	6-phospho-beta-galactosidase activity
D5082_RS17010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D5082_RS17025	COG2194	sulfuric ester hydrolase activity
D5082_RS17030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D5082_RS17045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5082_RS17050	COG0765	amino acid transport
D5082_RS17055	COG1126	abc transporter atp-binding protein
D5082_RS17060	COG0668	transmembrane transport
D5082_RS17070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D5082_RS17080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D5082_RS17090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D5082_RS17095	COG1199	ATP-dependent helicase activity
D5082_RS17100	COG0513	Belongs to the DEAD box helicase family
D5082_RS17105	COG3958	Transketolase
D5082_RS17110	COG3959	Transketolase, thiamine diphosphate binding domain
D5082_RS17115	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS17120	COG2271	Major facilitator Superfamily
D5082_RS17125	COG0583	DNA-binding transcription factor activity
D5082_RS17130	COG1309	transcriptional regulator
D5082_RS17135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5082_RS17140	COG1131	(ABC) transporter
D5082_RS17145	COG0842	Transport permease protein
D5082_RS17150	COG0842	Transport permease protein
D5082_RS17165	COG3568	Endonuclease Exonuclease Phosphatase
D5082_RS17170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D5082_RS17175	COG0392	lysyltransferase activity
D5082_RS17195	COG0670	Belongs to the BI1 family
D5082_RS17200	COG0314	molybdopterin synthase activity
D5082_RS17205	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D5082_RS17215	COG0521	Mo-molybdopterin cofactor biosynthetic process
D5082_RS17240	COG0745	RESPONSE REGULATOR receiver
D5082_RS17245	COG0642	Histidine kinase
D5082_RS17280	COG2226	methyltransferase
D5082_RS17300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D5082_RS17305	COG1881	PFAM PEBP family protein
D5082_RS17340	COG4677	pectinesterase activity
D5082_RS17350	COG0589	response to stress
D5082_RS17355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5082_RS17385	COG0789	Transcriptional regulator
D5082_RS17390	COG2200	EAL domain
D5082_RS17415	COG0561	phosphatase activity
D5082_RS17425	COG4149	molybdate abc transporter
D5082_RS17430	COG0725	ABC transporter, periplasmic molybdate-binding protein
D5082_RS17440	COG2005	Transcriptional regulator
D5082_RS17440	COG3585	molybdate ion transport
D5082_RS17445	COG1119	ATPase activity
D5082_RS17455	COG1085	galactose-1-phosphate uridylyltransferase
D5082_RS17465	COG2017	converts alpha-aldose to the beta-anomer
D5082_RS17475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D5082_RS17490	COG3201	nicotinamide mononucleotide transporter
D5082_RS17495	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D5082_RS17540	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
D5082_RS17545	COG2885	chlorophyll binding
D5082_RS17555	COG3064	Membrane
D5082_RS17560	COG0848	biopolymer transport protein
D5082_RS17565	COG0811	peptide transport
D5082_RS17570	COG0824	Thioesterase
D5082_RS17575	COG3790	cyd operon protein YbgE
D5082_RS17580	COG4890	Cyd operon protein YbgT
D5082_RS17585	COG1294	oxidase, subunit
D5082_RS17590	COG1271	oxidase subunit
D5082_RS17600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D5082_RS17610	COG0508	dehydrogenase complex catalyzes the overall conversion of
D5082_RS17615	COG0567	Dehydrogenase, E1 component
D5082_RS17620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D5082_RS17625	COG1053	succinate dehydrogenase
D5082_RS17630	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D5082_RS17635	COG2009	succinate dehydrogenase
D5082_RS17670	COG1984	allophanate hydrolase subunit 2
D5082_RS17675	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D5082_RS17690	COG0415	Belongs to the DNA photolyase family
D5082_RS17720	COG2205	protein histidine kinase activity
D5082_RS17725	COG0745	RESPONSE REGULATOR receiver
D5082_RS17735	COG0033	Phosphoglucomutase
D5082_RS17745	COG0596	Alpha beta hydrolase
D5082_RS17760	COG0735	belongs to the Fur family
D5082_RS17805	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D5082_RS17810	COG1940	carbohydrate kinase activity
D5082_RS17810	COG1846	Transcriptional regulator
D5082_RS17815	COG0647	UMP catabolic process
D5082_RS17820	COG0367	asparagine synthase
D5082_RS17865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D5082_RS17875	COG1702	phosphate starvation-inducible protein PhoH
D5082_RS17900	COG0765	amino acid transport
D5082_RS17905	COG0765	amino acid transport
D5082_RS17910	COG1126	abc transporter atp-binding protein
D5082_RS17925	COG2888	peptidyl-tyrosine sulfation
D5082_RS17940	COG1466	dna polymerase III delta subunit
D5082_RS17960	COG0799	negative regulation of ribosome biogenesis
D5082_RS17970	COG0768	penicillin binding
D5082_RS17975	COG0772	Belongs to the SEDS family
D5082_RS17980	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D5082_RS17985	COG1686	Belongs to the peptidase S11 family
D5082_RS18000	COG0583	DNA-binding transcription factor activity
D5082_RS18010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D5082_RS18015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D5082_RS18035	COG3069	C4-dicarboxylate transmembrane transporter activity
D5082_RS18040	COG3719	Belongs to the RNase T2 family
D5082_RS18045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D5082_RS18065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D5082_RS18070	COG0583	DNA-binding transcription factor activity
D5082_RS18080	COG3969	phosphoadenosine phosphosulfate
D5082_RS18085	COG1475	DNA binding
D5082_RS18090	COG0436	Aminotransferase
D5082_RS18115	COG1129	ABC transporter
D5082_RS18120	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS18125	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS18135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D5082_RS18150	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D5082_RS18160	COG0402	S-adenosylhomocysteine deaminase activity
D5082_RS18170	COG0483	inositol monophosphate 1-phosphatase activity
D5082_RS18175	COG2271	Major facilitator Superfamily
D5082_RS18205	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS18210	COG1129	ABC transporter
D5082_RS18215	COG0371	Dehydrogenase
D5082_RS18220	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS18235	COG2879	small protein
D5082_RS18240	COG1966	Carbon starvation protein
D5082_RS18250	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS18255	COG3433	isochorismatase activity
D5082_RS18255	COG1535	isochorismatase
D5082_RS18260	COG1021	2,3-dihydroxybenzoate-AMP ligase
D5082_RS18265	COG1169	isochorismate synthase
D5082_RS18270	COG4592	Periplasmic binding protein
D5082_RS18280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D5082_RS18285	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D5082_RS18290	COG1120	ATPase activity
D5082_RS18295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D5082_RS18295	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D5082_RS18300	COG3251	PFAM MbtH domain protein
D5082_RS18305	COG2382	esterase
D5082_RS18310	COG4771	TonB-dependent receptor
D5082_RS18320	COG1879	ABC-type sugar transport system periplasmic component
D5082_RS18330	COG1129	ABC transporter
D5082_RS18335	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS18340	COG5464	transposase or invertase
D5082_RS18345	COG2390	Transcriptional regulator
D5082_RS18350	COG3959	Transketolase, thiamine diphosphate binding domain
D5082_RS18355	COG3958	Transketolase
D5082_RS18365	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D5082_RS18375	COG0583	DNA-binding transcription factor activity
D5082_RS18380	COG0668	transmembrane transport
D5082_RS18390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D5082_RS18415	COG0747	negative chemotaxis
D5082_RS18420	COG0601	transmembrane transport
D5082_RS18425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5082_RS18430	COG0444	Belongs to the ABC transporter superfamily
D5082_RS18435	COG4608	Belongs to the ABC transporter superfamily
D5082_RS18455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D5082_RS18460	COG4221	oxidoreductase activity
D5082_RS18470	COG4215	(ABC) transporter
D5082_RS18475	COG0765	amino acid transport
D5082_RS18480	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
D5082_RS18495	COG0697	spore germination
D5082_RS18510	COG4608	Belongs to the ABC transporter superfamily
D5082_RS18515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5082_RS18525	COG4166	transmembrane transport
D5082_RS18535	COG3698	Phosphodiester glycosidase
D5082_RS18580	COG2315	Protein conserved in bacteria
D5082_RS18615	COG0477	Major facilitator Superfamily
D5082_RS18620	COG0668	transmembrane transport
D5082_RS18625	COG1609	Transcriptional regulator
D5082_RS18635	COG0673	inositol 2-dehydrogenase activity
D5082_RS18645	COG2211	Major facilitator Superfamily
D5082_RS18650	COG1113	amino acid transport
D5082_RS18665	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS18670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D5082_RS18680	COG0531	amino acid
D5082_RS18695	COG4680	protein conserved in bacteria
D5082_RS18750	COG0667	Aldo Keto reductase
D5082_RS18755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5082_RS18760	COG1473	amidohydrolase
D5082_RS18780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D5082_RS18785	COG1120	ATPase activity
D5082_RS18790	COG1566	PFAM secretion protein HlyD family protein
D5082_RS18835	COG4211	Belongs to the binding-protein-dependent transport system permease family
D5082_RS18840	COG1129	ABC transporter
D5082_RS18855	COG0673	inositol 2-dehydrogenase activity
D5082_RS18890	COG3104	oligopeptide transport
D5082_RS18895	COG1982	Orn Lys Arg decarboxylase major
D5082_RS18900	COG0531	amino acid
D5082_RS18905	COG3710	Transcriptional regulator
D5082_RS18915	COG1560	Kdo2-lipid A biosynthetic process
D5082_RS18965	COG2501	S4 domain
D5082_RS18975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D5082_RS18995	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D5082_RS19000	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D5082_RS19015	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
D5082_RS19020	COG4181	ATPase activity
D5082_RS19025	COG2755	lipolytic protein G-D-S-L family
D5082_RS19030	COG0300	oxidoreductase activity
D5082_RS19035	COG3118	belongs to the thioredoxin family
D5082_RS19045	COG0390	transport system, permease component
D5082_RS19050	COG4619	ABC transporter
D5082_RS19055	COG0330	HflC and HflK could
D5082_RS19060	COG1585	Membrane protein implicated in regulation of membrane protease activity
D5082_RS19075	COG3735	TraB family
D5082_RS19080	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D5082_RS19090	COG2223	nitrite transmembrane transporter activity
D5082_RS19095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D5082_RS19095	COG4651	solute:proton antiporter activity
D5082_RS19100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5082_RS19140	COG2832	Protein of unknown function (DUF454)
D5082_RS19145	COG3923	Primosomal replication protein n
D5082_RS19155	COG5464	transposase or invertase
D5082_RS19160	COG1196	nuclear chromosome segregation
D5082_RS19160	COG3264	Mechanosensitive ion channel
D5082_RS19165	COG1309	transcriptional regulator
D5082_RS19170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5082_RS19175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5082_RS19190	COG0110	maltose O-acetyltransferase activity
D5082_RS19235	COG1874	Beta-galactosidase
D5082_RS19240	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D5082_RS19245	COG3833	ABC-type maltose transport systems, permease component
D5082_RS19250	COG1175	transmembrane transport
D5082_RS19255	COG2182	Extracellular solute-binding protein
D5082_RS19265	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D5082_RS19280	COG2364	Membrane
D5082_RS19310	COG3695	enzyme binding
D5082_RS19315	COG3126	Type III secretion system lipoprotein chaperone (YscW)
D5082_RS19320	COG1946	Acyl-CoA thioesterase
D5082_RS19325	COG0004	ammonium transporteR
D5082_RS19330	COG0347	Belongs to the P(II) protein family
D5082_RS19335	COG1132	(ABC) transporter
D5082_RS19340	COG1132	(ABC) transporter
D5082_RS19345	COG1522	sequence-specific DNA binding
D5082_RS19360	COG4533	DNA binding
D5082_RS19370	COG0824	Thioesterase
D5082_RS19375	COG1555	photosystem II stabilization
D5082_RS19380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D5082_RS19385	COG0776	regulation of translation
D5082_RS19390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D5082_RS19420	COG0271	Belongs to the BolA IbaG family
D5082_RS19425	COG3056	Lipoprotein
D5082_RS19430	COG2223	nitrite transmembrane transporter activity
D5082_RS19435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D5082_RS19440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D5082_RS19445	COG1845	cytochrome c oxidase, subunit III
D5082_RS19450	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D5082_RS19465	COG1414	Transcriptional regulator
D5082_RS19470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D5082_RS19475	COG1053	succinate dehydrogenase
D5082_RS19485	COG1053	succinate dehydrogenase
D5082_RS19500	COG0673	inositol 2-dehydrogenase activity
D5082_RS19505	COG2814	Major facilitator Superfamily
D5082_RS19515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D5082_RS19520	COG0693	protein deglycase activity
D5082_RS19540	COG0142	geranyltranstransferase activity
D5082_RS19550	COG0667	Aldo Keto reductase
D5082_RS19555	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D5082_RS19575	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D5082_RS19575	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D5082_RS19585	COG4238	major outer membrane lipoprotein
D5082_RS19605	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D5082_RS19610	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D5082_RS19615	COG1862	Preprotein translocase
D5082_RS19635	COG0450	alkyl hydroperoxide reductase
D5082_RS19640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS19655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5082_RS19665	COG1228	amidohydrolase
D5082_RS19675	COG1335	isochorismatase
D5082_RS19680	COG0583	DNA-binding transcription factor activity
D5082_RS19685	COG0366	Alpha amylase catalytic
D5082_RS19710	COG0420	3'-5' exonuclease activity
D5082_RS19715	COG0419	ATPase involved in DNA repair
D5082_RS19720	COG1940	carbohydrate kinase activity
D5082_RS19735	COG4126	flavin adenine dinucleotide binding
D5082_RS19745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D5082_RS19750	COG3416	Protein conserved in bacteria
D5082_RS19760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D5082_RS19770	COG1785	Belongs to the alkaline phosphatase family
D5082_RS19810	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
D5082_RS19815	COG1335	isochorismatase
D5082_RS19820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D5082_RS19825	COG0113	porphobilinogen synthase activity
D5082_RS19830	COG1943	Transposase
D5082_RS19840	COG2175	clavaminate synthase activity
D5082_RS19845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D5082_RS19850	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D5082_RS19855	COG4521	taurine ABC transporter
D5082_RS19860	COG2040	homocysteine
D5082_RS19865	COG0833	amino acid
D5082_RS19875	COG4303	Ethanolamine ammonia lyase large subunit
D5082_RS19880	COG4302	ethanolamine ammonia-lyase activity
D5082_RS19915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5082_RS19920	COG1126	abc transporter atp-binding protein
D5082_RS19925	COG4597	amino acid ABC transporter
D5082_RS19930	COG0765	amino acid transport
D5082_RS19945	COG3188	usher protein
D5082_RS19970	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
D5082_RS19980	COG3639	organic phosphonate transmembrane transporter activity
D5082_RS20005	COG0791	NLP P60 protein
D5082_RS20030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D5082_RS20065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D5082_RS20070	COG0022	dehydrogenase e1 component
D5082_RS20075	COG0508	dehydrogenase complex catalyzes the overall conversion of
D5082_RS20080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D5082_RS20105	COG1070	Carbohydrate kinase
D5082_RS20110	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS20115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D5082_RS20120	COG3775	system Galactitol-specific IIC component
D5082_RS20125	COG0625	glutathione transferase activity
D5082_RS20130	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D5082_RS20150	COG0579	oxidoreductase
D5082_RS20155	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS20160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D5082_RS20165	COG1113	amino acid transport
D5082_RS20170	COG1802	Transcriptional regulator
D5082_RS20190	COG2195	Cleaves the N-terminal amino acid of tripeptides
D5082_RS20195	COG0454	-acetyltransferase
D5082_RS20210	COG2991	Protein conserved in bacteria
D5082_RS20225	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D5082_RS20230	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D5082_RS20250	COG3034	peptidoglycan biosynthetic process
D5082_RS20255	COG0121	glutamine amidotransferase
D5082_RS20265	COG1960	acyl-CoA dehydrogenase activity
D5082_RS20270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D5082_RS20280	COG0583	DNA-binding transcription factor activity
D5082_RS20290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D5082_RS20300	COG2226	methyltransferase
D5082_RS20310	COG0741	lytic transglycosylase activity
D5082_RS20310	COG1388	LysM domain
D5082_RS20315	COG2226	methyltransferase
D5082_RS20330	COG0583	DNA-binding transcription factor activity
D5082_RS20335	COG0656	L-ascorbic acid biosynthetic process
D5082_RS20375	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D5082_RS20385	COG2011	ABC-type metal ion transport system permease component
D5082_RS20390	COG1464	Belongs to the NlpA lipoprotein family
D5082_RS20400	COG1720	tRNA m6t6A37 methyltransferase activity
D5082_RS20410	COG0791	NLP P60 protein
D5082_RS20415	COG3015	lipoprotein NlpE involved in copper resistance
D5082_RS20420	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
D5082_RS20435	COG4568	rho-dependent transcription termination
D5082_RS20445	COG0346	lactoylglutathione lyase activity
D5082_RS20450	COG1982	Orn Lys Arg decarboxylase major
D5082_RS20460	COG0587	DNA-directed DNA polymerase activity
D5082_RS20490	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
D5082_RS20500	COG0750	zinc metalloprotease
D5082_RS20505	COG0575	Belongs to the CDS family
D5082_RS20520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D5082_RS20545	COG0024	Methionine aminopeptidase
D5082_RS20550	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
D5082_RS20565	COG3835	regulator
D5082_RS20570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D5082_RS20590	COG2860	membrane
D5082_RS20610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D5082_RS20615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D5082_RS20620	COG1120	ATPase activity
D5082_RS20630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D5082_RS20720	COG1643	Atp-dependent helicase
D5082_RS20725	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D5082_RS20745	COG0617	tRNA 3'-terminal CCA addition
D5082_RS20750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D5082_RS20770	COG0726	polysaccharide deacetylase
D5082_RS20775	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS20780	COG0842	Transport permease protein
D5082_RS20785	COG1131	(ABC) transporter
D5082_RS20790	COG0288	reversible hydration of carbon dioxide
D5082_RS20800	COG4993	Dehydrogenase
D5082_RS20805	COG2132	Multicopper oxidase
D5082_RS20845	COG3064	Membrane
D5082_RS20860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D5082_RS20865	COG0508	dehydrogenase complex catalyzes the overall conversion of
D5082_RS20870	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D5082_RS20875	COG2186	Transcriptional regulator
D5082_RS20880	COG1113	amino acid transport
D5082_RS20885	COG2211	Major facilitator Superfamily
D5082_RS20890	COG3940	Belongs to the glycosyl hydrolase 43 family
D5082_RS20895	COG3725	Membrane protein required for beta-lactamase induction
D5082_RS20900	COG3023	N-Acetylmuramoyl-L-alanine amidase
D5082_RS20910	COG4969	Belongs to the N-Me-Phe pilin family
D5082_RS20915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D5082_RS20920	COG1459	type II secretion system
D5082_RS20945	COG0494	nUDIX hydrolase
D5082_RS20965	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D5082_RS20970	COG0849	cell division
D5082_RS20995	COG0772	Belongs to the SEDS family
D5082_RS21010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D5082_RS21015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D5082_RS21020	COG0768	penicillin binding
D5082_RS21040	COG1609	Transcriptional regulator
D5082_RS21050	COG0028	Belongs to the TPP enzyme family
D5082_RS21100	COG0738	Major facilitator superfamily
D5082_RS21110	COG0583	DNA-binding transcription factor activity
D5082_RS21115	COG2271	Major facilitator Superfamily
D5082_RS21120	COG2814	Major facilitator Superfamily
D5082_RS21140	COG1178	ABC-type Fe3 transport system permease component
D5082_RS21150	COG0586	Pfam SNARE associated Golgi protein
D5082_RS21170	COG0235	Class ii aldolase
D5082_RS21175	COG0417	DNA replication proofreading
D5082_RS21185	COG0564	pseudouridine synthase activity
D5082_RS21200	COG3493	citrate carrier protein
D5082_RS21215	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D5082_RS21220	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
D5082_RS21230	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D5082_RS21280	COG0505	Belongs to the CarA family
D5082_RS21295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D5082_RS21305	COG3152	Membrane
D5082_RS21320	COG1047	Peptidyl-prolyl cis-trans
D5082_RS21335	COG0196	riboflavin kinase activity
D5082_RS21350	COG0583	DNA-binding transcription factor activity
D5082_RS21375	COG4735	regulation of single-species biofilm formation
D5082_RS21380	COG1584	GPR1 FUN34 yaaH family protein
D5082_RS21385	COG0477	Major facilitator Superfamily
D5082_RS21390	COG0521	Mo-molybdopterin cofactor biosynthetic process
D5082_RS21395	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D5082_RS21400	COG1115	amino acid carrier protein
D5082_RS21415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D5082_RS21425	COG0460	homoserine dehydrogenase
D5082_RS21425	COG0527	aspartate kinase activity
D5082_RS21435	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
D5082_RS21450	COG0745	RESPONSE REGULATOR receiver
D5082_RS21455	COG4452	Inner membrane protein CreD
D5082_RS21460	COG2205	protein histidine kinase activity
D5082_RS21465	COG0745	RESPONSE REGULATOR receiver
D5082_RS21470	COG3045	CreA protein
D5082_RS21475	COG2207	Transcriptional regulator
D5082_RS21475	COG3708	Transcriptional regulator
D5082_RS21495	COG0741	lytic transglycosylase activity
D5082_RS21510	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D5082_RS21515	COG0560	Phosphoserine phosphatase
D5082_RS21525	COG3726	membrane protein affecting hemolysin expression
D5082_RS21555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D5082_RS21560	COG0084	hydrolase, TatD family'
D5082_RS21565	COG4667	esterase of the alpha-beta hydrolase superfamily
D5082_RS21570	COG5487	UPF0391 membrane protein
D5082_RS21575	COG2823	Periplasmic or secreted lipoprotein
D5082_RS21585	COG1011	Hydrolase
D5082_RS21590	COG0456	acetyltransferase
D5082_RS21595	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
D5082_RS21625	COG3706	GGDEF domain
D5082_RS21630	COG4114	ferric iron reductase
D5082_RS21635	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS21635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS21640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D5082_RS21645	COG2197	response regulator
D5082_RS21650	COG2197	response regulator
D5082_RS21665	COG2966	Psort location CytoplasmicMembrane, score
D5082_RS21680	COG1484	DNA-dependent DNA replication
D5082_RS21695	COG5464	transposase or invertase
D5082_RS21705	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D5082_RS21710	COG3716	PTS system mannose fructose sorbose family IID component
D5082_RS21715	COG3715	PTS system
D5082_RS21730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D5082_RS21730	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D5082_RS21735	COG0456	acetyltransferase
D5082_RS21735	COG1214	PFAM Peptidase M22, glycoprotease
D5082_RS21745	COG1737	Transcriptional regulator
D5082_RS21750	COG0800	Aldolase
D5082_RS21755	COG3734	2-keto-3-deoxy-galactonokinase
D5082_RS21770	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
D5082_RS21800	COG1846	Transcriptional regulator
D5082_RS21805	COG0179	Fumarylacetoacetate (FAA) hydrolase
D5082_RS21815	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS21820	COG3384	dioxygenase
D5082_RS21830	COG3971	2-oxopent-4-enoate hydratase activity
D5082_RS21850	COG2368	4-hydroxyphenylacetate
D5082_RS21855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D5082_RS21870	COG1966	Carbon starvation protein
D5082_RS21875	COG2879	small protein
D5082_RS21880	COG0523	cobalamin synthesis protein
D5082_RS21890	COG1012	belongs to the aldehyde dehydrogenase family
D5082_RS21895	COG5464	transposase or invertase
D5082_RS21900	COG2207	Transcriptional regulator
D5082_RS21900	COG1917	Cupin 2, conserved barrel domain protein
D5082_RS21910	COG2733	membrane
D5082_RS21925	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
D5082_RS21930	COG1924	4 iron, 4 sulfur cluster binding
D5082_RS21945	COG1566	PFAM secretion protein HlyD family protein
D5082_RS21955	COG5457	Domain of unknown function (DUF1127)
D5082_RS21960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D5082_RS21970	COG0583	DNA-binding transcription factor activity
D5082_RS21975	COG2249	NAD(P)H dehydrogenase (quinone) activity
D5082_RS21985	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS21990	COG1129	ABC transporter
D5082_RS21995	COG1879	ABC-type sugar transport system periplasmic component
D5082_RS22005	COG3706	GGDEF domain
D5082_RS22010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5082_RS22015	COG1129	ABC transporter
D5082_RS22015	COG0842	Transport permease protein
D5082_RS22020	COG0842	Transport permease protein
D5082_RS22055	COG2850	peptidyl-arginine hydroxylation
D5082_RS22070	COG5002	protein histidine kinase activity
D5082_RS22075	COG0745	RESPONSE REGULATOR receiver
D5082_RS22085	COG1538	Outer membrane efflux protein
D5082_RS22090	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5082_RS22095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D5082_RS22100	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5082_RS22110	COG3040	lipid binding
D5082_RS22115	COG0789	Transcriptional regulator
D5082_RS22120	COG3631	Ketosteroid isomerase-related protein
D5082_RS22125	COG0300	oxidoreductase activity
D5082_RS22140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D5082_RS22160	COG3272	Protein of unknown function (DUF1722)
D5082_RS22165	COG4580	involved in the transport of maltose and maltodextrins
D5082_RS22170	COG2115	Belongs to the xylose isomerase family
D5082_RS22175	COG2211	Major facilitator Superfamily
D5082_RS22180	COG3507	Belongs to the glycosyl hydrolase 43 family
D5082_RS22200	COG1216	Glycosyl transferase, family 2
D5082_RS22260	COG1715	Restriction endonuclease
D5082_RS22265	COG1196	nuclear chromosome segregation
D5082_RS22285	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
D5082_RS22290	COG0582	viral genome integration into host DNA
D5082_RS22305	COG0288	reversible hydration of carbon dioxide
D5082_RS22310	COG0659	secondary active sulfate transmembrane transporter activity
D5082_RS22315	COG1064	alcohol dehydrogenase
D5082_RS22320	COG1175	transmembrane transport
D5082_RS22325	COG0395	ABC-type sugar transport system, permease component
D5082_RS22330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D5082_RS22335	COG3842	ATPase activity
D5082_RS22350	COG1082	Xylose isomerase domain protein TIM barrel
D5082_RS22360	COG3962	Belongs to the TPP enzyme family
D5082_RS22365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5082_RS22370	COG0837	glucose binding
D5082_RS22370	COG1737	Transcriptional regulator
D5082_RS22395	COG3718	enzyme involved in inositol metabolism
D5082_RS22410	COG0433	COG0433 Predicted ATPase
D5082_RS22415	COG0795	lipopolysaccharide-transporting ATPase activity
D5082_RS22420	COG0795	lipopolysaccharide-transporting ATPase activity
D5082_RS22435	COG2927	DNA polymerase III (CHI subunit)
D5082_RS22440	COG0525	valine-tRNA ligase activity
D5082_RS22465	COG2731	YhcH YjgK YiaL family protein
D5082_RS22510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D5082_RS22510	COG1263	PTS System
D5082_RS22515	COG0366	Alpha amylase catalytic
D5082_RS22520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS22525	COG1486	melibiose metabolic process
D5082_RS22545	COG0602	queuosine metabolic process
D5082_RS22550	COG2026	Addiction module toxin, RelE StbE family
D5082_RS22555	COG3077	Addiction module antitoxin, RelB DinJ family
D5082_RS22560	COG3711	transcriptional antiterminator
D5082_RS22560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D5082_RS22565	COG2706	6-phosphogluconolactonase activity
D5082_RS22580	COG3964	amidohydrolase
D5082_RS22615	COG0312	modulator of DNA gyrase
D5082_RS22635	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D5082_RS22645	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS22650	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS22655	COG1129	ABC transporter
D5082_RS22660	COG1879	ABC-type sugar transport system periplasmic component
D5082_RS22675	COG2105	PFAM AIG2 family protein
D5082_RS22680	COG2911	Protein conserved in bacteria
D5082_RS22685	COG0729	surface antigen
D5082_RS22695	COG1253	flavin adenine dinucleotide binding
D5082_RS22720	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
D5082_RS22735	COG1733	regulation of RNA biosynthetic process
D5082_RS22740	COG0702	epimerase
D5082_RS22750	COG0697	spore germination
D5082_RS22760	COG1113	amino acid transport
D5082_RS22765	COG0545	Peptidyl-prolyl cis-trans isomerase
D5082_RS22770	COG3061	Opacity-associated protein A
D5082_RS22780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D5082_RS22785	COG2965	DNA replication, synthesis of RNA primer
D5082_RS22845	COG1073	alpha beta
D5082_RS22850	COG3650	response to hydrogen peroxide
D5082_RS22860	COG1960	acyl-CoA dehydrogenase activity
D5082_RS22865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D5082_RS22870	COG0557	exoribonuclease II activity
D5082_RS22885	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
D5082_RS22895	COG0330	HflC and HflK could
D5082_RS22900	COG0330	HflC and HflK could
D5082_RS22905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D5082_RS22925	COG0860	N-Acetylmuramoyl-L-alanine amidase
D5082_RS22930	COG0802	atpase or kinase
D5082_RS22935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D5082_RS22935	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D5082_RS22940	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D5082_RS22965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D5082_RS22990	COG1511	domain protein
D5082_RS22990	COG3264	Mechanosensitive ion channel
D5082_RS23005	COG1053	succinate dehydrogenase
D5082_RS23010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D5082_RS23030	COG2076	Multidrug Resistance protein
D5082_RS23035	COG5510	response to toxic substance
D5082_RS23050	COG1509	lysine 2,3-aminomutase activity
D5082_RS23115	COG0531	amino acid
D5082_RS23120	COG3030	protein affecting phage T7 exclusion by the F plasmid
D5082_RS23130	COG1027	Aspartate ammonia-lyase
D5082_RS23135	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D5082_RS23150	COG1309	transcriptional regulator
D5082_RS23180	COG0457	Tetratricopeptide repeat
D5082_RS23185	COG1649	PFAM Uncharacterised BCR, COG1649
D5082_RS23185	COG0726	polysaccharide deacetylase
D5082_RS23190	COG1215	transferase activity, transferring glycosyl groups
D5082_RS23210	COG0861	Integral membrane protein TerC family
D5082_RS23240	COG1486	melibiose metabolic process
D5082_RS23250	COG2169	Transcriptional regulator
D5082_RS23265	COG2824	Alkylphosphonate utilization operon protein PhnA
D5082_RS23270	COG2764	glyoxalase bleomycin resistance protein dioxygenase
D5082_RS23275	COG2188	Transcriptional regulator
D5082_RS23280	COG3624	Phosphonate C-P lyase system protein PhnG
D5082_RS23285	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
D5082_RS23290	COG3626	phosphonate metabolism
D5082_RS23295	COG3627	carbon phosphorus lyase activity
D5082_RS23300	COG4107	phosphonate C-P lyase system protein PhnK
D5082_RS23305	COG4778	phosphonate C-P lyase system protein PhnL
D5082_RS23310	COG3454	Phosphonate metabolism
D5082_RS23320	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D5082_RS23330	COG4191	Histidine kinase
D5082_RS23330	COG0784	Response regulator, receiver
D5082_RS23335	COG1129	ABC transporter
D5082_RS23340	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS23375	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
D5082_RS23380	COG1301	dicarboxylic acid transport
D5082_RS23390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D5082_RS23400	COG3162	membrane
D5082_RS23430	COG3539	Fimbrial protein
D5082_RS23435	COG1346	cytolysis
D5082_RS23440	COG1380	Effector of murein hydrolase LrgA
D5082_RS23445	COG0583	DNA-binding transcription factor activity
D5082_RS23450	COG0025	NhaP-type Na H and K H
D5082_RS23455	COG2252	PERMEase
D5082_RS23460	COG0625	glutathione transferase activity
D5082_RS23465	COG0789	Transcriptional regulator
D5082_RS23475	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D5082_RS23510	COG1234	tRNA 3'-trailer cleavage
D5082_RS23515	COG1609	Transcriptional regulator
D5082_RS23520	COG0483	inositol monophosphate 1-phosphatase activity
D5082_RS23535	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D5082_RS23555	COG4771	TonB-dependent receptor
D5082_RS23560	COG0741	lytic transglycosylase activity
D5082_RS23580	COG2315	Protein conserved in bacteria
D5082_RS23585	COG0432	Pfam Uncharacterised protein family UPF0047
D5082_RS23600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D5082_RS23605	COG0305	Participates in initiation and elongation during chromosome replication
D5082_RS23620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D5082_RS23630	COG0735	belongs to the Fur family
D5082_RS23635	COG3237	CsbD-like
D5082_RS23640	COG0534	Mate efflux family protein
D5082_RS23650	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D5082_RS23725	COG0251	oxidation-reduction process
D5082_RS23735	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D5082_RS23755	COG0527	aspartate kinase activity
D5082_RS23805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D5082_RS23815	COG0456	acetyltransferase
D5082_RS23855	COG0151	Belongs to the GarS family
D5082_RS23865	COG4191	Histidine kinase
D5082_RS23870	COG3678	ATP-independent chaperone mediated protein folding
D5082_RS23905	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
D5082_RS23920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D5082_RS23925	COG2104	thiamine diphosphate biosynthetic process
D5082_RS23945	COG3706	GGDEF domain
D5082_RS23955	COG1447	Phosphotransferase system cellobiose-specific component IIA
D5082_RS23960	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D5082_RS24000	COG0250	Participates in transcription elongation, termination and antitermination
D5082_RS24050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D5082_RS24080	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
D5082_RS24090	COG1739	Uncharacterized protein family UPF0029
D5082_RS24135	COG0805	protein transport
D5082_RS24155	COG3165	ubiquinone biosynthetic process from chorismate
D5082_RS24185	COG0583	DNA-binding transcription factor activity
D5082_RS24190	COG0697	spore germination
D5082_RS24195	COG0561	phosphatase activity
D5082_RS24200	COG2267	carboxylic ester hydrolase activity
D5082_RS24205	COG1280	lysine exporter protein (LysE YggA)
D5082_RS24215	COG1280	lysine exporter protein (LysE YggA)
D5082_RS24250	COG0210	DNA helicase
D5082_RS24255	COG1011	Hydrolase
D5082_RS24285	COG3072	Adenylate cyclase
D5082_RS24300	COG2959	enzyme of heme biosynthesis
D5082_RS24305	COG3071	HemY protein
D5082_RS24350	COG2244	polysaccharide biosynthetic process
D5082_RS24355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D5082_RS24360	COG0456	acetyltransferase
D5082_RS24365	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D5082_RS24370	COG1088	dTDP-glucose 4,6-dehydratase activity
D5082_RS24375	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D5082_RS24380	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D5082_RS24390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D5082_RS24395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D5082_RS24405	COG3118	belongs to the thioredoxin family
D5082_RS24435	COG1811	Na channel or pump
D5082_RS24445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D5082_RS24450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D5082_RS24460	COG0583	DNA-binding transcription factor activity
D5082_RS24465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D5082_RS24480	COG3978	acetolactate synthase activity
D5082_RS24500	COG3085	chromosome segregation
D5082_RS24575	COG0583	DNA-binding transcription factor activity
D5082_RS24600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D5082_RS24615	COG3443	Belongs to the bacterial solute-binding protein 9 family
D5082_RS24620	COG2207	Transcriptional regulator
D5082_RS24630	COG0371	Dehydrogenase
D5082_RS24635	COG0697	spore germination
D5082_RS24645	COG0583	DNA-binding transcription factor activity
D5082_RS24655	COG0737	Belongs to the 5'-nucleotidase family
D5082_RS24665	COG0460	homoserine dehydrogenase
D5082_RS24665	COG0527	aspartate kinase activity
D5082_RS24670	COG0626	cystathionine gamma-synthase activity
D5082_RS24685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D5082_RS24690	COG1609	Transcriptional regulator
D5082_RS24695	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D5082_RS24710	COG1575	Belongs to the MenA family. Type 1 subfamily
D5082_RS24730	COG3678	ATP-independent chaperone mediated protein folding
D5082_RS24735	COG0745	RESPONSE REGULATOR receiver
D5082_RS24740	COG2205	protein histidine kinase activity
D5082_RS24745	COG2258	MOSC domain
D5082_RS24750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D5082_RS24795	COG1129	ABC transporter
D5082_RS24800	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS24805	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS24810	COG1454	alcohol dehydrogenase
D5082_RS24820	COG2211	Major facilitator Superfamily
D5082_RS24860	COG0243	molybdopterin cofactor binding
D5082_RS24860	COG3383	formate dehydrogenase (NAD+) activity
D5082_RS24865	COG3383	formate dehydrogenase (NAD+) activity
D5082_RS24865	COG0243	molybdopterin cofactor binding
D5082_RS24870	COG0437	4 iron, 4 sulfur cluster binding
D5082_RS24875	COG2864	formate dehydrogenase
D5082_RS24890	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D5082_RS24900	COG0456	acetyltransferase
D5082_RS24915	COG1011	Hydrolase
D5082_RS24935	COG3852	Histidine kinase
D5082_RS24945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D5082_RS24975	COG0204	Acyl-transferase
D5082_RS24985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D5082_RS24990	COG3084	Protein conserved in bacteria
D5082_RS25000	COG1763	Mo-molybdopterin cofactor biosynthetic process
D5082_RS25030	COG2186	Transcriptional regulator
D5082_RS25035	COG0477	Major facilitator Superfamily
D5082_RS25040	COG1609	Transcriptional regulator
D5082_RS25045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5082_RS25055	COG1172	Belongs to the binding-protein-dependent transport system permease family
D5082_RS25060	COG1129	ABC transporter
D5082_RS25090	COG1522	sequence-specific DNA binding
D5082_RS25095	COG0716	FMN binding
D5082_RS25110	COG3312	ion transport
D5082_RS25160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D5082_RS25270	COG0675	Transposase, IS605 OrfB family
D5082_RS25285	COG0675	Transposase, IS605 OrfB family
D5082_RS25295	COG2026	Addiction module toxin, RelE StbE family
D5082_RS25305	COG0210	DNA helicase
D5082_RS25420	COG3344	reverse transcriptase
D5082_RS25530	COG0482	sulfurtransferase activity
D5082_RS25545	COG0488	(ABC) transporter
D5082_RS25550	COG3173	Aminoglycoside phosphotransferase
D5082_RS25555	COG2801	Transposase and inactivated derivatives
D5082_RS25595	COG2826	transposase and inactivated derivatives, IS30 family
D5082_RS25620	COG0673	inositol 2-dehydrogenase activity
D5082_RS25625	COG1324	tolerance protein
D5082_RS25655	COG2826	transposase and inactivated derivatives, IS30 family
D5082_RS25830	COG0633	Ferredoxin
D5082_RS25890	COG1484	DNA-dependent DNA replication
D5082_RS26150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D5082_RS26155	COG0573	inorganic phosphate transmembrane transporter activity
D5082_RS26160	COG0581	inorganic phosphate transmembrane transporter activity
D5082_RS26165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D5082_RS26170	COG0704	Plays a role in the regulation of phosphate uptake
D5082_RS26185	COG2382	esterase
D5082_RS26190	COG0363	glucosamine-6-phosphate deaminase activity
D5082_RS26195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D5082_RS26205	COG2252	PERMEase
D5082_RS26210	COG0431	NADPH-dependent FMN reductase
D5082_RS26215	COG2091	lysine biosynthetic process via aminoadipic acid
D5082_RS26245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D5082_RS26280	COG0187	DNA topoisomerase II activity
D5082_RS26285	COG0561	phosphatase activity
D5082_RS26300	COG2186	Transcriptional regulator
D5082_RS26305	COG3734	2-keto-3-deoxy-galactonokinase
D5082_RS26310	COG0800	Aldolase
D5082_RS26320	COG2271	Major facilitator Superfamily
D5082_RS26325	COG0823	Involved in the tonB-independent uptake of proteins
D5082_RS26330	COG5645	(Lipo)protein
D5082_RS26345	COG3645	SOS response
D5082_RS26355	COG2188	Transcriptional regulator
D5082_RS26370	COG2149	membrane
D5082_RS26390	COG2610	gluconate transmembrane transporter activity
D5082_RS26395	COG0583	DNA-binding transcription factor activity
D5082_RS26400	COG2814	Major facilitator Superfamily
D5082_RS26425	COG0028	Belongs to the TPP enzyme family
D5082_RS26430	COG0440	acetolactate synthase activity
D5082_RS26435	COG2197	response regulator
D5082_RS26445	COG2271	Major facilitator Superfamily
D5082_RS26490	COG2188	Transcriptional regulator
D5082_RS26515	COG4580	involved in the transport of maltose and maltodextrins
D5082_RS26520	COG1447	Phosphotransferase system cellobiose-specific component IIA
D5082_RS26525	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS26525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D5082_RS26535	COG1609	Transcriptional regulator
D5082_RS26550	COG0583	DNA-binding transcription factor activity
D5082_RS26555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D5082_RS26560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D5082_RS26565	COG2828	Protein conserved in bacteria
D5082_RS26580	COG0697	spore germination
D5082_RS26585	COG1263	PTS System
D5082_RS26585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D5082_RS26595	COG2814	Major facilitator Superfamily
D5082_RS26605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D5082_RS26640	COG0583	DNA-binding transcription factor activity
D5082_RS26665	COG1464	Belongs to the NlpA lipoprotein family
D5082_RS26680	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D5082_RS26690	COG1064	alcohol dehydrogenase
D5082_RS26720	COG2211	Major facilitator Superfamily
D5082_RS26725	COG1501	Belongs to the glycosyl hydrolase 31 family
D5082_RS26735	COG1486	melibiose metabolic process
D5082_RS26740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D5082_RS26740	COG1263	PTS System
D5082_RS26745	COG2982	Protein involved in outer membrane biogenesis
D5082_RS26750	COG2233	PERMEase
D5082_RS26755	COG0786	glutamate:sodium symporter activity
D5082_RS26775	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D5082_RS26800	COG3152	Membrane
D5082_RS26810	COG1494	fructose-1,6-bisphosphatase
D5082_RS26815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D5082_RS26820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D5082_RS26825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D5082_RS26845	COG2860	membrane
D5082_RS26855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D5082_RS26855	COG2169	Transcriptional regulator
D5082_RS26860	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D5082_RS26865	COG1561	YicC-like family, N-terminal region
D5082_RS26885	COG1131	(ABC) transporter
D5082_RS26890	COG0842	Transport permease protein
D5082_RS26920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D5082_RS26955	COG1519	Transferase
D5082_RS26960	COG1216	Glycosyl transferase, family 2
D5082_RS26965	COG0438	transferase activity, transferring glycosyl groups
D5082_RS26975	COG0859	PFAM glycosyl transferase family 9
D5082_RS27000	COG0859	PFAM glycosyl transferase family 9
D5082_RS27015	COG0156	8-amino-7-oxononanoate synthase activity
D5082_RS27025	COG0463	Glycosyl transferase, family 2
D5082_RS27030	COG2861	carbohydrate metabolic process
D5082_RS27035	COG4942	peptidase
D5082_RS27045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D5082_RS27050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D5082_RS27070	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D5082_RS27080	COG2186	Transcriptional regulator
D5082_RS27100	COG3722	fumarate hydratase activity
D5082_RS27120	COG0625	glutathione transferase activity
D5082_RS27130	COG3276	selenocysteine insertion sequence binding
D5082_RS27135	COG1414	Transcriptional regulator
D5082_RS27140	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
D5082_RS27145	COG3977	Valine--pyruvate aminotransferase
D5082_RS27150	COG0366	Alpha amylase catalytic
D5082_RS27160	COG2992	FlgJ-related protein
D5082_RS27165	COG2207	Transcriptional regulator
D5082_RS27165	COG1609	Transcriptional regulator
D5082_RS27170	COG4214	carbohydrate transport
D5082_RS27180	COG4213	ABC transporter substrate-binding protein
D5082_RS27200	COG4682	membrane
D5082_RS27205	COG4682	membrane
D5082_RS27210	COG3274	enterobacterial common antigen metabolic process
D5082_RS27250	COG1278	Cold shock
D5082_RS27255	COG2944	sequence-specific DNA binding
D5082_RS27260	COG2814	Major facilitator Superfamily
D5082_RS27285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D5082_RS27295	COG1609	Transcriptional regulator
D5082_RS27300	COG2885	chlorophyll binding
D5082_RS27305	COG0243	molybdopterin cofactor binding
D5082_RS27310	COG0456	acetyltransferase
D5082_RS27315	COG2818	Glycosylase
D5082_RS27320	COG5571	outer membrane autotransporter
D5082_RS27325	COG2223	nitrite transmembrane transporter activity
D5082_RS27355	COG0747	negative chemotaxis
D5082_RS27360	COG0601	transmembrane transport
D5082_RS27365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5082_RS27370	COG0444	Belongs to the ABC transporter superfamily
D5082_RS27375	COG4608	Belongs to the ABC transporter superfamily
D5082_RS27390	COG2894	cell division
D5082_RS27400	COG1215	transferase activity, transferring glycosyl groups
D5082_RS27405	COG0457	Tetratricopeptide repeat
D5082_RS27420	COG2194	sulfuric ester hydrolase activity
D5082_RS27450	COG1215	transferase activity, transferring glycosyl groups
D5082_RS27455	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D5082_RS27460	COG3118	belongs to the thioredoxin family
D5082_RS27460	COG0457	Tetratricopeptide repeat
D5082_RS27465	COG2200	EAL domain
D5082_RS27465	COG2199	diguanylate cyclase activity
D5082_RS27475	COG0612	Peptidase, M16
D5082_RS27490	COG2982	Protein involved in outer membrane biogenesis
D5082_RS27495	COG0477	Major facilitator Superfamily
D5082_RS27505	COG1295	ribonuclease BN
D5082_RS27510	COG0583	DNA-binding transcription factor activity
D5082_RS27515	COG1028	Short-chain dehydrogenase reductase Sdr
D5082_RS27520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D5082_RS27530	COG1454	alcohol dehydrogenase
D5082_RS27540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D5082_RS27545	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D5082_RS27550	COG0671	phosphoesterase, PA-phosphatase related
D5082_RS27570	COG0589	response to stress
D5082_RS27580	COG0306	phosphate transporter
D5082_RS27585	COG2081	HI0933 family
D5082_RS27615	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D5082_RS27620	COG1196	nuclear chromosome segregation
D5082_RS27650	COG2239	Acts as a magnesium transporter
D5082_RS27665	COG1124	(ABC) transporter
D5082_RS27675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D5082_RS27680	COG0601	transmembrane transport
D5082_RS27685	COG0747	negative chemotaxis
D5082_RS27700	COG3479	Phenolic acid decarboxylase
D5082_RS27740	COG0628	permease
D5082_RS27745	COG0477	Major facilitator Superfamily
D5082_RS27755	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D5082_RS27770	COG3714	YhhN family
D5082_RS27780	COG3776	membrane
D5082_RS27785	COG0742	ribosomal rna small subunit methyltransferase
D5082_RS27790	COG0552	protein localization to endoplasmic reticulum
D5082_RS27795	COG2884	Cell division ATP-binding protein ftsE
D5082_RS27800	COG2177	Part of the ABC transporter FtsEX involved in
D5082_RS27815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D5082_RS27825	COG0683	leucine binding
D5082_RS27855	COG2203	Gaf domain
D5082_RS27855	COG2199	diguanylate cyclase activity
D5082_RS27860	COG5001	Diguanylate cyclase
D5082_RS27860	COG1716	ATPase activity
D5082_RS27885	COG5001	Diguanylate cyclase
D5082_RS27895	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D5082_RS27935	COG4372	Transposase
D5082_RS27940	COG3436	PFAM IS66 Orf2 family protein
D5082_RS27995	COG3318	Belongs to the UPF0149 family
D5082_RS27995	COG3012	SEC-C Motif Domain Protein
D5082_RS28020	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
D5082_RS28245	COG5499	transcription regulator containing HTH domain
D5082_RS28400	COG3344	reverse transcriptase
D5082_RS28485	COG3344	reverse transcriptase
D5082_RS28515	COG0789	Transcriptional regulator