locus-tag	class	description
F6W81_RS00020	COG0187	DNA topoisomerase II activity
F6W81_RS00025	COG0561	phosphatase activity
F6W81_RS00040	COG2186	Transcriptional regulator
F6W81_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
F6W81_RS00050	COG0800	Aldolase
F6W81_RS00075	COG2271	Major facilitator Superfamily
F6W81_RS00080	COG0823	Involved in the tonB-independent uptake of proteins
F6W81_RS00085	COG5645	(Lipo)protein
F6W81_RS00100	COG3645	SOS response
F6W81_RS00110	COG2188	Transcriptional regulator
F6W81_RS00125	COG2149	membrane
F6W81_RS00145	COG2610	gluconate transmembrane transporter activity
F6W81_RS00150	COG0583	DNA-binding transcription factor activity
F6W81_RS00155	COG2814	Major facilitator Superfamily
F6W81_RS00180	COG0028	Belongs to the TPP enzyme family
F6W81_RS00185	COG0440	acetolactate synthase activity
F6W81_RS00190	COG2197	response regulator
F6W81_RS00200	COG2271	Major facilitator Superfamily
F6W81_RS00245	COG2188	Transcriptional regulator
F6W81_RS00270	COG4580	involved in the transport of maltose and maltodextrins
F6W81_RS00275	COG1447	Phosphotransferase system cellobiose-specific component IIA
F6W81_RS00280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6W81_RS00280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6W81_RS00290	COG1609	Transcriptional regulator
F6W81_RS00300	COG3384	dioxygenase
F6W81_RS00305	COG0583	DNA-binding transcription factor activity
F6W81_RS00310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F6W81_RS00315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F6W81_RS00320	COG2828	Protein conserved in bacteria
F6W81_RS00335	COG0697	spore germination
F6W81_RS00340	COG1263	PTS System
F6W81_RS00340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6W81_RS00350	COG2814	Major facilitator Superfamily
F6W81_RS00360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6W81_RS00395	COG0583	DNA-binding transcription factor activity
F6W81_RS00420	COG1464	Belongs to the NlpA lipoprotein family
F6W81_RS00435	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F6W81_RS00445	COG1064	alcohol dehydrogenase
F6W81_RS00480	COG2211	Major facilitator Superfamily
F6W81_RS00485	COG1501	Belongs to the glycosyl hydrolase 31 family
F6W81_RS00495	COG1486	melibiose metabolic process
F6W81_RS00500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6W81_RS00500	COG1263	PTS System
F6W81_RS00505	COG2982	Protein involved in outer membrane biogenesis
F6W81_RS00510	COG2233	PERMEase
F6W81_RS00515	COG0786	glutamate:sodium symporter activity
F6W81_RS00535	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F6W81_RS00560	COG3152	Membrane
F6W81_RS00570	COG1494	fructose-1,6-bisphosphatase
F6W81_RS00575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F6W81_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F6W81_RS00585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F6W81_RS00605	COG2860	membrane
F6W81_RS00615	COG2169	Transcriptional regulator
F6W81_RS00615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F6W81_RS00620	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
F6W81_RS00625	COG1561	YicC-like family, N-terminal region
F6W81_RS00630	COG3039	Transposase
F6W81_RS00660	COG1131	(ABC) transporter
F6W81_RS00665	COG0842	Transport permease protein
F6W81_RS00690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F6W81_RS00725	COG1519	Transferase
F6W81_RS00735	COG0438	transferase activity, transferring glycosyl groups
F6W81_RS00745	COG0859	PFAM glycosyl transferase family 9
F6W81_RS00770	COG0859	PFAM glycosyl transferase family 9
F6W81_RS00785	COG0156	8-amino-7-oxononanoate synthase activity
F6W81_RS00795	COG0463	Glycosyl transferase, family 2
F6W81_RS00800	COG2861	carbohydrate metabolic process
F6W81_RS00805	COG4942	peptidase
F6W81_RS00815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F6W81_RS00820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F6W81_RS00840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F6W81_RS00850	COG2186	Transcriptional regulator
F6W81_RS00870	COG3722	fumarate hydratase activity
F6W81_RS00890	COG1566	PFAM secretion protein HlyD family protein
F6W81_RS00895	COG0625	glutathione transferase activity
F6W81_RS00905	COG3276	selenocysteine insertion sequence binding
F6W81_RS00910	COG1414	Transcriptional regulator
F6W81_RS00915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6W81_RS00920	COG3977	Valine--pyruvate aminotransferase
F6W81_RS00925	COG0366	Alpha amylase catalytic
F6W81_RS00930	COG2992	FlgJ-related protein
F6W81_RS00935	COG2207	Transcriptional regulator
F6W81_RS00935	COG1609	Transcriptional regulator
F6W81_RS00940	COG4214	carbohydrate transport
F6W81_RS00950	COG4213	ABC transporter substrate-binding protein
F6W81_RS00965	COG4682	membrane
F6W81_RS00970	COG4682	membrane
F6W81_RS00975	COG3274	enterobacterial common antigen metabolic process
F6W81_RS01000	COG3039	Transposase
F6W81_RS01020	COG1278	Cold shock
F6W81_RS01025	COG2944	sequence-specific DNA binding
F6W81_RS01030	COG2814	Major facilitator Superfamily
F6W81_RS01055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6W81_RS01065	COG1609	Transcriptional regulator
F6W81_RS01070	COG2885	chlorophyll binding
F6W81_RS01075	COG0243	molybdopterin cofactor binding
F6W81_RS01080	COG0456	acetyltransferase
F6W81_RS01085	COG2818	Glycosylase
F6W81_RS01090	COG5571	outer membrane autotransporter
F6W81_RS01095	COG2223	nitrite transmembrane transporter activity
F6W81_RS01125	COG0747	negative chemotaxis
F6W81_RS01130	COG0601	transmembrane transport
F6W81_RS01135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6W81_RS01140	COG0444	Belongs to the ABC transporter superfamily
F6W81_RS01145	COG4608	Belongs to the ABC transporter superfamily
F6W81_RS01170	COG1215	transferase activity, transferring glycosyl groups
F6W81_RS01175	COG0457	Tetratricopeptide repeat
F6W81_RS01190	COG2194	sulfuric ester hydrolase activity
F6W81_RS01220	COG1215	transferase activity, transferring glycosyl groups
F6W81_RS01225	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F6W81_RS01230	COG0457	Tetratricopeptide repeat
F6W81_RS01230	COG3118	belongs to the thioredoxin family
F6W81_RS01235	COG2200	EAL domain
F6W81_RS01235	COG2199	diguanylate cyclase activity
F6W81_RS01245	COG0612	Peptidase, M16
F6W81_RS01260	COG2982	Protein involved in outer membrane biogenesis
F6W81_RS01265	COG0477	Major facilitator Superfamily
F6W81_RS01270	COG1295	ribonuclease BN
F6W81_RS01275	COG0583	DNA-binding transcription factor activity
F6W81_RS01280	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS01285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F6W81_RS01295	COG1454	alcohol dehydrogenase
F6W81_RS01305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F6W81_RS01310	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F6W81_RS01315	COG0671	phosphoesterase, PA-phosphatase related
F6W81_RS01335	COG0589	response to stress
F6W81_RS01345	COG0306	phosphate transporter
F6W81_RS01350	COG2081	HI0933 family
F6W81_RS01355	COG2239	Acts as a magnesium transporter
F6W81_RS01365	COG1124	(ABC) transporter
F6W81_RS01375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6W81_RS01380	COG0601	transmembrane transport
F6W81_RS01385	COG0747	negative chemotaxis
F6W81_RS01395	COG3479	Phenolic acid decarboxylase
F6W81_RS01435	COG0628	permease
F6W81_RS01440	COG0477	Major facilitator Superfamily
F6W81_RS01450	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F6W81_RS01465	COG3714	YhhN family
F6W81_RS01475	COG3776	membrane
F6W81_RS01480	COG0742	ribosomal rna small subunit methyltransferase
F6W81_RS01485	COG0552	protein localization to endoplasmic reticulum
F6W81_RS01490	COG2884	Cell division ATP-binding protein ftsE
F6W81_RS01495	COG2177	Part of the ABC transporter FtsEX involved in
F6W81_RS01510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F6W81_RS01520	COG0683	leucine binding
F6W81_RS01535	COG0683	leucine binding
F6W81_RS01540	COG0559	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS01590	COG0584	glycerophosphoryl diester phosphodiesterase
F6W81_RS01600	COG0405	Gamma-glutamyltransferase
F6W81_RS01605	COG1247	-acetyltransferase
F6W81_RS01615	COG0673	inositol 2-dehydrogenase activity
F6W81_RS01620	COG1741	Belongs to the pirin family
F6W81_RS01625	COG1609	Transcriptional regulator
F6W81_RS01630	COG3265	gluconokinase activity
F6W81_RS01635	COG2610	gluconate transmembrane transporter activity
F6W81_RS01645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F6W81_RS01670	COG0058	SHG alpha-glucan phosphorylase activity
F6W81_RS01685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F6W81_RS01700	COG1349	DNA-binding transcription factor activity
F6W81_RS01710	COG0058	SHG alpha-glucan phosphorylase activity
F6W81_RS01715	COG1640	4-alpha-glucanotransferase
F6W81_RS01720	COG2610	gluconate transmembrane transporter activity
F6W81_RS01730	COG1040	competence protein
F6W81_RS01755	COG1918	ferrous iron import across plasma membrane
F6W81_RS01760	COG2183	response to ionizing radiation
F6W81_RS01765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F6W81_RS01790	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F6W81_RS01795	COG1011	Hydrolase
F6W81_RS01805	COG0494	nUDIX hydrolase
F6W81_RS01810	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F6W81_RS01835	COG4796	Type ii and iii secretion system protein
F6W81_RS01850	COG3266	domain, Protein
F6W81_RS01855	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F6W81_RS01860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F6W81_RS01885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F6W81_RS01890	COG0402	S-adenosylhomocysteine deaminase activity
F6W81_RS01895	COG0738	Major facilitator superfamily
F6W81_RS01920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F6W81_RS01925	COG1289	transmembrane transporter activity
F6W81_RS01935	COG1765	OsmC-like protein
F6W81_RS01940	COG3954	Phosphoribulokinase
F6W81_RS01950	COG0429	hydrolase of the alpha beta-hydrolase fold
F6W81_RS01960	COG0488	(ABC) transporter
F6W81_RS01975	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F6W81_RS01980	COG1047	Peptidyl-prolyl cis-trans
F6W81_RS01990	COG0545	Peptidyl-prolyl cis-trans isomerase
F6W81_RS01995	COG2964	Protein conserved in bacteria
F6W81_RS02050	COG0051	transcription antitermination factor activity, RNA binding
F6W81_RS02075	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F6W81_RS02090	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F6W81_RS02155	COG0201	protein transport
F6W81_RS02180	COG0202	RNA polymerase activity
F6W81_RS02195	COG0789	Transcriptional regulator
F6W81_RS02200	COG3036	rescue of stalled ribosome
F6W81_RS02230	COG0758	DNA mediated transformation
F6W81_RS02240	COG0551	DNA topoisomerase type I activity
F6W81_RS02260	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F6W81_RS02295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6W81_RS02300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6W81_RS02305	COG1309	transcriptional regulator
F6W81_RS02310	COG0582	viral genome integration into host DNA
F6W81_RS02325	COG3561	AntA/AntB antirepressor
F6W81_RS02415	COG4626	Terminase
F6W81_RS02415	COG1802	Transcriptional regulator
F6W81_RS02445	COG4145	pantothenate transmembrane transporter activity
F6W81_RS02450	COG3924	membrane
F6W81_RS02455	COG0439	Biotin carboxylase
F6W81_RS02460	COG0511	ligase activity, forming carbon-carbon bonds
F6W81_RS02485	COG2200	EAL domain
F6W81_RS02485	COG2199	diguanylate cyclase activity
F6W81_RS02490	COG1077	Cell shape determining protein MreB Mrl
F6W81_RS02495	COG1792	Involved in formation and maintenance of cell shape
F6W81_RS02500	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F6W81_RS02510	COG1530	ribonuclease E activity
F6W81_RS02515	COG3164	Protein of unknown function
F6W81_RS02520	COG0312	modulator of DNA gyrase
F6W81_RS02525	COG0583	DNA-binding transcription factor activity
F6W81_RS02540	COG1289	transmembrane transporter activity
F6W81_RS02545	COG2732	(Barnase) inhibitor
F6W81_RS02570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F6W81_RS02575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F6W81_RS02580	COG3105	Protein conserved in bacteria
F6W81_RS02585	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F6W81_RS02600	COG0625	glutathione transferase activity
F6W81_RS02605	COG2969	positive regulation of protein catabolic process
F6W81_RS02615	COG0493	'glutamate synthase
F6W81_RS02620	COG0069	glutamate synthase activity
F6W81_RS02620	COG0070	glutamate synthase
F6W81_RS02620	COG0067	glutamate synthase
F6W81_RS02625	COG1242	4 iron, 4 sulfur cluster binding
F6W81_RS02630	COG2271	Major facilitator Superfamily
F6W81_RS02635	COG1063	alcohol dehydrogenase
F6W81_RS02640	COG1312	Catalyzes the dehydration of D-mannonate
F6W81_RS02645	COG0784	Response regulator, receiver
F6W81_RS02645	COG2198	Histidine kinase
F6W81_RS02645	COG5002	protein histidine kinase activity
F6W81_RS02650	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
F6W81_RS02655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F6W81_RS02660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS02670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS02675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F6W81_RS02680	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F6W81_RS02685	COG1137	ATPase activity
F6W81_RS02690	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F6W81_RS02695	COG3117	lipopolysaccharide transmembrane transporter activity
F6W81_RS02700	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F6W81_RS02710	COG0530	calcium, potassium:sodium antiporter activity
F6W81_RS02720	COG1127	ABC transporter
F6W81_RS02725	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F6W81_RS02730	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F6W81_RS02735	COG2854	intermembrane phospholipid transfer
F6W81_RS02740	COG3113	response to antibiotic
F6W81_RS02745	COG5007	Belongs to the BolA IbaG family
F6W81_RS02755	COG3423	Transcriptional regulator
F6W81_RS02760	COG0142	geranyltranstransferase activity
F6W81_RS02775	COG0697	spore germination
F6W81_RS02785	COG2027	D-alanyl-D-alanine carboxypeptidase
F6W81_RS02795	COG1534	Rna-binding protein
F6W81_RS02805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F6W81_RS02810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F6W81_RS02820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F6W81_RS02860	COG0195	Participates in both transcription termination and antitermination
F6W81_RS02905	COG0814	amino acid
F6W81_RS02910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6W81_RS02915	COG0826	peptidase U32
F6W81_RS02920	COG0826	peptidase U32
F6W81_RS02925	COG3154	lipid carrier protein
F6W81_RS02930	COG3153	acetyltransferase
F6W81_RS02945	COG0693	protein deglycase activity
F6W81_RS02950	COG0702	epimerase
F6W81_RS02955	COG0701	Predicted permease
F6W81_RS02960	COG2823	Periplasmic or secreted lipoprotein
F6W81_RS02980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F6W81_RS02995	COG1063	alcohol dehydrogenase
F6W81_RS03000	COG3775	system Galactitol-specific IIC component
F6W81_RS03005	COG3414	Phosphotransferase system galactitol-specific IIB component
F6W81_RS03010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS03020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS03020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS03025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS03025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6W81_RS03025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6W81_RS03035	COG1105	Belongs to the carbohydrate kinase PfkB family
F6W81_RS03045	COG1349	DNA-binding transcription factor activity
F6W81_RS03050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6W81_RS03055	COG2721	sulfolactate sulfo-lyase activity
F6W81_RS03065	COG2271	Major facilitator Superfamily
F6W81_RS03075	COG2084	Dehydrogenase
F6W81_RS03080	COG1929	Belongs to the glycerate kinase type-1 family
F6W81_RS03100	COG1741	Belongs to the pirin family
F6W81_RS03105	COG0583	DNA-binding transcription factor activity
F6W81_RS03110	COG3152	Membrane
F6W81_RS03115	COG0435	Glutathione S-transferase
F6W81_RS03120	COG2259	Doxx family
F6W81_RS03130	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
F6W81_RS03135	COG4575	ribosome binding
F6W81_RS03140	COG1422	Protein of unknown function (DUF1090)
F6W81_RS03150	COG0586	Pfam SNARE associated Golgi protein
F6W81_RS03155	COG2186	Transcriptional regulator
F6W81_RS03160	COG2271	Major facilitator Superfamily
F6W81_RS03170	COG2721	sulfolactate sulfo-lyase activity
F6W81_RS03185	COG0861	Integral membrane protein TerC family
F6W81_RS03190	COG0673	inositol 2-dehydrogenase activity
F6W81_RS03195	COG1451	nucleotide metabolic process
F6W81_RS03215	COG1902	pentaerythritol trinitrate reductase activity
F6W81_RS03215	COG0446	pyridine nucleotide-disulphide oxidoreductase
F6W81_RS03265	COG1695	Transcriptional regulator
F6W81_RS03270	COG2375	cellular response to nickel ion
F6W81_RS03285	COG1461	Dihydroxyacetone kinase
F6W81_RS03290	COG2376	Dihydroxyacetone kinase
F6W81_RS03365	COG3247	response to pH
F6W81_RS03375	COG2198	Histidine kinase
F6W81_RS03375	COG0784	Response regulator, receiver
F6W81_RS03375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6W81_RS03375	COG2205	protein histidine kinase activity
F6W81_RS03380	COG2197	response regulator
F6W81_RS03405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F6W81_RS03410	COG0358	DNA primase activity
F6W81_RS03415	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F6W81_RS03475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F6W81_RS03490	COG4991	sh3 domain protein
F6W81_RS03495	COG3025	triphosphatase activity
F6W81_RS03515	COG2960	long-chain fatty acid transporting porin activity
F6W81_RS03530	COG3384	dioxygenase
F6W81_RS03535	COG0754	glutathionylspermidine amidase activity
F6W81_RS03550	COG0494	nUDIX hydrolase
F6W81_RS03555	COG3151	Protein conserved in bacteria
F6W81_RS03560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F6W81_RS03565	COG3150	esterase
F6W81_RS03575	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F6W81_RS03580	COG2249	NAD(P)H dehydrogenase (quinone) activity
F6W81_RS03585	COG0642	Histidine kinase
F6W81_RS03595	COG3111	PFAM Bacterial OB fold (BOF) protein
F6W81_RS03600	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F6W81_RS03605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F6W81_RS03610	COG0204	Acyl-transferase
F6W81_RS03615	COG2132	Multicopper oxidase
F6W81_RS03620	COG1032	radical SAM domain protein
F6W81_RS03630	COG0656	L-ascorbic acid biosynthetic process
F6W81_RS03635	COG1979	alcohol dehydrogenase
F6W81_RS03640	COG2207	Transcriptional regulator
F6W81_RS03645	COG0586	Pfam SNARE associated Golgi protein
F6W81_RS03650	COG0626	cystathionine gamma-synthase activity
F6W81_RS03660	COG0848	biopolymer transport protein
F6W81_RS03665	COG2211	Major facilitator Superfamily
F6W81_RS03690	COG0625	glutathione transferase activity
F6W81_RS03700	COG0754	glutathionylspermidine amidase activity
F6W81_RS03705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F6W81_RS03725	COG0583	DNA-binding transcription factor activity
F6W81_RS03730	COG0626	cystathionine gamma-synthase activity
F6W81_RS03995	COG3423	Transcriptional regulator
F6W81_RS04005	COG1278	Cold shock
F6W81_RS04010	COG3423	Transcriptional regulator
F6W81_RS04070	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F6W81_RS04080	COG1811	Na channel or pump
F6W81_RS04090	COG1982	Orn Lys Arg decarboxylase major
F6W81_RS04095	COG2211	Major facilitator Superfamily
F6W81_RS04110	COG1194	a g-specific adenine glycosylase
F6W81_RS04120	COG3171	Protein conserved in bacteria
F6W81_RS04130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F6W81_RS04145	COG0762	integral membrane protein
F6W81_RS04150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F6W81_RS04155	COG2805	Type II/IV secretion system protein
F6W81_RS04175	COG0189	ligase activity
F6W81_RS04180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F6W81_RS04185	COG2356	endonuclease I
F6W81_RS04195	COG2814	Major facilitator Superfamily
F6W81_RS04230	COG2146	nitrite reductase [NAD(P)H] activity
F6W81_RS04245	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS04250	COG1414	Transcriptional regulator
F6W81_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS04285	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
F6W81_RS04315	COG0501	Belongs to the peptidase M48B family
F6W81_RS04320	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F6W81_RS04335	COG0191	fructose-bisphosphate aldolase activity
F6W81_RS04340	COG0668	transmembrane transport
F6W81_RS04350	COG2968	Membrane
F6W81_RS04365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F6W81_RS04370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F6W81_RS04390	COG0006	proline dipeptidase activity
F6W81_RS04395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F6W81_RS04400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F6W81_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS04425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F6W81_RS04445	COG2723	6-phospho-beta-galactosidase activity
F6W81_RS04450	COG1737	Transcriptional regulator
F6W81_RS04460	COG1272	protein, Hemolysin III
F6W81_RS04470	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F6W81_RS04480	COG0716	FMN binding
F6W81_RS04485	COG4974	Belongs to the 'phage' integrase family
F6W81_RS04495	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F6W81_RS04515	COG4942	peptidase
F6W81_RS04525	COG2814	Major facilitator Superfamily
F6W81_RS04540	COG0667	Aldo Keto reductase
F6W81_RS04575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F6W81_RS04580	COG1393	Belongs to the ArsC family
F6W81_RS04595	COG1538	Outer membrane efflux protein
F6W81_RS04600	COG1289	transmembrane transporter activity
F6W81_RS04615	COG3592	Divergent 4Fe-4S mono-cluster
F6W81_RS04620	COG2388	GCN5-related N-acetyl-transferase
F6W81_RS04630	COG3539	Fimbrial protein
F6W81_RS04635	COG3539	Fimbrial protein
F6W81_RS04640	COG3539	Fimbrial protein
F6W81_RS04645	COG3188	usher protein
F6W81_RS04650	COG3121	Chaperone
F6W81_RS04655	COG3539	Fimbrial protein
F6W81_RS04665	COG4974	Belongs to the 'phage' integrase family
F6W81_RS04670	COG0582	viral genome integration into host DNA
F6W81_RS04680	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F6W81_RS04685	COG1846	Transcriptional regulator
F6W81_RS04690	COG0697	spore germination
F6W81_RS04740	COG0667	Aldo Keto reductase
F6W81_RS04745	COG0814	amino acid
F6W81_RS04760	COG0183	Belongs to the thiolase family
F6W81_RS04770	COG0823	Involved in the tonB-independent uptake of proteins
F6W81_RS04775	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS04780	COG2814	Major facilitator Superfamily
F6W81_RS04810	COG3842	ATPase activity
F6W81_RS04815	COG0395	ABC-type sugar transport system, permease component
F6W81_RS04820	COG1175	transmembrane transport
F6W81_RS04825	COG1917	Cupin 2, conserved barrel domain protein
F6W81_RS04830	COG1794	racemase activity, acting on amino acids and derivatives
F6W81_RS04835	COG0583	DNA-binding transcription factor activity
F6W81_RS04845	COG1609	Transcriptional regulator
F6W81_RS04850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6W81_RS04855	COG2723	6-phospho-beta-galactosidase activity
F6W81_RS04860	COG2186	Transcriptional regulator
F6W81_RS04870	COG1609	Transcriptional regulator
F6W81_RS04885	COG0667	Aldo Keto reductase
F6W81_RS04895	COG0861	Integral membrane protein TerC family
F6W81_RS04930	COG2165	general secretion pathway protein
F6W81_RS04935	COG4795	General secretion pathway protein
F6W81_RS04945	COG4967	type IV pilus modification protein PilV
F6W81_RS04950	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F6W81_RS04955	COG1025	Belongs to the peptidase M16 family
F6W81_RS04960	COG1074	ATP-dependent DNA helicase activity
F6W81_RS04965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F6W81_RS04975	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F6W81_RS04975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F6W81_RS04980	COG0860	N-Acetylmuramoyl-L-alanine amidase
F6W81_RS04985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F6W81_RS05015	COG4656	Part of a membrane complex involved in electron transport
F6W81_RS05020	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS05020	COG1454	alcohol dehydrogenase
F6W81_RS05050	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
F6W81_RS05215	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F6W81_RS05220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F6W81_RS05225	COG2166	iron-sulfur cluster assembly
F6W81_RS05230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F6W81_RS05240	COG0583	DNA-binding transcription factor activity
F6W81_RS05245	COG2363	Small membrane protein
F6W81_RS05255	COG1349	DNA-binding transcription factor activity
F6W81_RS05275	COG0738	Major facilitator superfamily
F6W81_RS05280	COG0235	Class ii aldolase
F6W81_RS05285	COG1454	alcohol dehydrogenase
F6W81_RS05300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6W81_RS05315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F6W81_RS05320	COG2011	ABC-type metal ion transport system permease component
F6W81_RS05325	COG1464	Belongs to the NlpA lipoprotein family
F6W81_RS05335	COG0477	Major facilitator Superfamily
F6W81_RS05345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F6W81_RS05350	COG1760	l-serine dehydratase
F6W81_RS05355	COG0814	amino acid
F6W81_RS05360	COG1611	Belongs to the LOG family
F6W81_RS05375	COG3098	single-species biofilm formation
F6W81_RS05380	COG0564	pseudouridine synthase activity
F6W81_RS05385	COG0716	FMN binding
F6W81_RS05390	COG2271	Major facilitator Superfamily
F6W81_RS05395	COG4948	Mandelate Racemase Muconate Lactonizing
F6W81_RS05400	COG4948	Mandelate Racemase Muconate Lactonizing
F6W81_RS05405	COG1929	Belongs to the glycerate kinase type-1 family
F6W81_RS05415	COG4999	Histidine kinase
F6W81_RS05415	COG3850	Histidine kinase
F6W81_RS05415	COG3437	response regulator, receiver
F6W81_RS05415	COG2205	protein histidine kinase activity
F6W81_RS05425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F6W81_RS05430	COG3956	TIGRFAM MazG family protein
F6W81_RS05450	COG0602	queuosine metabolic process
F6W81_RS05455	COG0720	synthase
F6W81_RS05475	COG2234	aminopeptidase activity
F6W81_RS05535	COG4942	peptidase
F6W81_RS05535	COG1388	LysM domain
F6W81_RS05540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F6W81_RS05565	COG0163	prenyltransferase activity
F6W81_RS05570	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F6W81_RS05615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6W81_RS05620	COG4558	Periplasmic binding protein
F6W81_RS05625	COG3720	iron ion transport
F6W81_RS05645	COG0679	Auxin Efflux Carrier
F6W81_RS05660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F6W81_RS05665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F6W81_RS05670	COG1121	(ABC) transporter
F6W81_RS05675	COG0803	Belongs to the bacterial solute-binding protein 9 family
F6W81_RS05680	COG1609	Transcriptional regulator
F6W81_RS05685	COG1940	carbohydrate kinase activity
F6W81_RS05690	COG1447	Phosphotransferase system cellobiose-specific component IIA
F6W81_RS05695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6W81_RS05700	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6W81_RS05705	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6W81_RS05715	COG4580	involved in the transport of maltose and maltodextrins
F6W81_RS05725	COG2723	6-phospho-beta-galactosidase activity
F6W81_RS05735	COG0309	Hydrogenase expression formation protein (HypE)
F6W81_RS05740	COG0409	Hydrogenase expression formation protein
F6W81_RS05745	COG0298	carbon dioxide binding
F6W81_RS05750	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F6W81_RS05770	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6W81_RS05775	COG0651	ATP synthesis coupled electron transport
F6W81_RS05780	COG0650	Formate hydrogenlyase subunit 4
F6W81_RS05785	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
F6W81_RS05785	COG3261	NADH dehydrogenase
F6W81_RS05790	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F6W81_RS05795	COG3260	NADH ubiquinone oxidoreductase 20
F6W81_RS05805	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F6W81_RS05815	COG2723	6-phospho-beta-galactosidase activity
F6W81_RS05820	COG1263	PTS System
F6W81_RS05820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6W81_RS05825	COG1609	Transcriptional regulator
F6W81_RS05830	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6W81_RS05835	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
F6W81_RS05840	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
F6W81_RS05870	COG1349	DNA-binding transcription factor activity
F6W81_RS05875	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS05880	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS05890	COG3732	PTS system glucitol sorbitol-specific
F6W81_RS05895	COG3730	PTS system glucitol sorbitol-specific
F6W81_RS05900	COG2951	lytic endotransglycosylase activity
F6W81_RS05910	COG1121	(ABC) transporter
F6W81_RS05915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F6W81_RS05925	COG1546	Belongs to the CinA family
F6W81_RS05950	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
F6W81_RS05980	COG2823	Periplasmic or secreted lipoprotein
F6W81_RS05985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F6W81_RS05990	COG1238	metal cluster binding
F6W81_RS06010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F6W81_RS06015	COG2814	Major facilitator Superfamily
F6W81_RS06020	COG1566	PFAM secretion protein HlyD family protein
F6W81_RS06025	COG1846	Transcriptional regulator
F6W81_RS06035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F6W81_RS06045	COG4176	ABC-type proline glycine betaine transport system permease component
F6W81_RS06060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F6W81_RS06070	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F6W81_RS06075	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F6W81_RS06080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F6W81_RS06085	COG4575	ribosome binding
F6W81_RS06110	COG2916	Histone family protein nucleoid-structuring protein H-NS
F6W81_RS06125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F6W81_RS06130	COG0640	Transcriptional regulator
F6W81_RS06140	COG0583	DNA-binding transcription factor activity
F6W81_RS06145	COG3284	Transcriptional regulator
F6W81_RS06155	COG3539	Fimbrial protein
F6W81_RS06160	COG3121	Chaperone
F6W81_RS06185	COG4974	Belongs to the 'phage' integrase family
F6W81_RS06220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F6W81_RS06240	COG3344	reverse transcriptase
F6W81_RS06275	COG4695	Portal protein
F6W81_RS06440	COG2867	negative regulation of translational initiation
F6W81_RS06455	COG0497	DNA recombination
F6W81_RS06470	COG4536	flavin adenine dinucleotide binding
F6W81_RS06475	COG4137	Cytochrome C assembly protein
F6W81_RS06480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F6W81_RS06515	COG2885	chlorophyll binding
F6W81_RS06520	COG2199	diguanylate cyclase activity
F6W81_RS06530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F6W81_RS06535	COG1605	Chorismate mutase
F6W81_RS06535	COG0287	Prephenate dehydrogenase
F6W81_RS06545	COG1605	Chorismate mutase
F6W81_RS06545	COG0077	Prephenate dehydratase
F6W81_RS06555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F6W81_RS06560	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F6W81_RS06575	COG0542	response to heat
F6W81_RS06605	COG0477	Major facilitator Superfamily
F6W81_RS06610	COG5544	Lipoprotein
F6W81_RS06615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F6W81_RS06625	COG3148	PFAM DTW domain containing protein
F6W81_RS06630	COG3118	belongs to the thioredoxin family
F6W81_RS06635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F6W81_RS06650	COG0513	Belongs to the DEAD box helicase family
F6W81_RS06660	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F6W81_RS06675	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
F6W81_RS06680	COG3026	antisigma factor binding
F6W81_RS06685	COG3086	response to oxidative stress
F6W81_RS06695	COG0681	Belongs to the peptidase S26 family
F6W81_RS06715	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F6W81_RS06725	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6W81_RS06730	COG1737	Transcriptional regulator
F6W81_RS06735	COG0560	Phosphoserine phosphatase
F6W81_RS06750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F6W81_RS06750	COG0047	phosphoribosylformylglycinamidine synthase activity
F6W81_RS06755	COG2205	protein histidine kinase activity
F6W81_RS06760	COG3170	Tfp pilus assembly protein FimV
F6W81_RS06765	COG2204	response regulator
F6W81_RS06770	COG0347	Belongs to the P(II) protein family
F6W81_RS06775	COG1017	nitric oxide dioxygenase activity
F6W81_RS06775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F6W81_RS06785	COG2259	Doxx family
F6W81_RS06790	COG1940	carbohydrate kinase activity
F6W81_RS06795	COG0457	Tetratricopeptide repeat
F6W81_RS06800	COG2814	Major facilitator Superfamily
F6W81_RS06800	COG0477	Major facilitator Superfamily
F6W81_RS06805	COG2017	converts alpha-aldose to the beta-anomer
F6W81_RS06810	COG2814	Major facilitator Superfamily
F6W81_RS06815	COG3711	transcriptional antiterminator
F6W81_RS06820	COG3683	transport system, periplasmic component
F6W81_RS06825	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F6W81_RS06855	COG0822	iron-sulfur transferase activity
F6W81_RS06875	COG0633	Ferredoxin
F6W81_RS06880	COG2975	iron-sulfur cluster assembly
F6W81_RS06900	COG2897	thiosulfate sulfurtransferase activity
F6W81_RS06905	COG2373	Large extracellular alpha-helical protein
F6W81_RS06910	COG4953	penicillin-binding protein 1C
F6W81_RS06945	COG2976	Protein conserved in bacteria
F6W81_RS06965	COG1645	bacterial-type flagellum-dependent swarming motility
F6W81_RS06975	COG0516	GMP reductase activity
F6W81_RS06975	COG0517	IMP dehydrogenase activity
F6W81_RS07025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F6W81_RS07105	COG3344	reverse transcriptase
F6W81_RS07120	COG3728	DNA packaging
F6W81_RS07120	COG5484	DNA packaging
F6W81_RS07280	COG3179	chitinase
F6W81_RS07290	COG3119	arylsulfatase activity
F6W81_RS07295	COG0641	radical SAM
F6W81_RS07315	COG2200	EAL domain
F6W81_RS07330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F6W81_RS07345	COG2723	6-phospho-beta-galactosidase activity
F6W81_RS07355	COG2233	PERMEase
F6W81_RS07370	COG1393	Belongs to the ArsC family
F6W81_RS07375	COG4783	chaperone-mediated protein folding
F6W81_RS07380	COG0628	permease
F6W81_RS07385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F6W81_RS07390	COG2716	regulation of RNA biosynthetic process
F6W81_RS07400	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
F6W81_RS07410	COG2321	neutral zinc metallopeptidase
F6W81_RS07415	COG1444	tRNA N-acetyltransferase activity
F6W81_RS07420	COG0400	carboxylic ester hydrolase activity
F6W81_RS07435	COG1393	Belongs to the ArsC family
F6W81_RS07445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6W81_RS07455	COG0493	'glutamate synthase
F6W81_RS07455	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F6W81_RS07465	COG5342	invasion associated locus B
F6W81_RS07470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F6W81_RS07475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F6W81_RS07485	COG4810	utilization protein
F6W81_RS07575	COG0860	N-Acetylmuramoyl-L-alanine amidase
F6W81_RS07595	COG2837	iron assimilation
F6W81_RS07605	COG4150	thiosulfate binding
F6W81_RS07610	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F6W81_RS07615	COG4208	sulfate ABC transporter
F6W81_RS07620	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F6W81_RS07630	COG4319	ketosteroid isomerase
F6W81_RS07665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F6W81_RS07685	COG3530	Putative quorum-sensing-regulated virulence factor
F6W81_RS07690	COG0385	Bile acid
F6W81_RS07695	COG0583	DNA-binding transcription factor activity
F6W81_RS07725	COG3415	Transposase
F6W81_RS07730	COG3415	Transposase
F6W81_RS07745	COG2199	diguanylate cyclase activity
F6W81_RS07745	COG2200	EAL domain
F6W81_RS07750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F6W81_RS07765	COG0667	Aldo Keto reductase
F6W81_RS07770	COG3961	Belongs to the TPP enzyme family
F6W81_RS07785	COG3279	Response regulator of the LytR AlgR family
F6W81_RS07790	COG3275	phosphorelay sensor kinase activity
F6W81_RS07800	COG0436	Aminotransferase
F6W81_RS07810	COG2807	transmembrane transport
F6W81_RS07815	COG0590	tRNA wobble adenosine to inosine editing
F6W81_RS07820	COG0583	DNA-binding transcription factor activity
F6W81_RS07840	COG2116	formate transmembrane transporter activity
F6W81_RS07845	COG2853	Lipoprotein
F6W81_RS07855	COG3691	Protein conserved in bacteria
F6W81_RS07870	COG2062	phosphohistidine phosphatase, SixA
F6W81_RS07895	COG0730	response to heat
F6W81_RS07900	COG3101	peptidyl-lysine hydroxylation
F6W81_RS07915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F6W81_RS07935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F6W81_RS07945	COG0586	Pfam SNARE associated Golgi protein
F6W81_RS07955	COG0285	dihydrofolate synthase activity
F6W81_RS07960	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
F6W81_RS07965	COG1286	toxin biosynthetic process
F6W81_RS07970	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F6W81_RS07975	COG0163	prenyltransferase activity
F6W81_RS07995	COG4160	amino acid transport
F6W81_RS08000	COG4598	ABC transporter
F6W81_RS08010	COG1090	epimerase
F6W81_RS08015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F6W81_RS08020	COG0625	glutathione transferase activity
F6W81_RS08025	COG0625	glutathione transferase activity
F6W81_RS08030	COG0622	Phosphoesterase
F6W81_RS08035	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
F6W81_RS08040	COG0280	phosphate acetyltransferase
F6W81_RS08040	COG0857	belongs to the CobB CobQ family
F6W81_RS08060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F6W81_RS08065	COG0490	domain, Protein
F6W81_RS08065	COG0471	metal ion transport
F6W81_RS08075	COG0436	Aminotransferase
F6W81_RS08080	COG0583	DNA-binding transcription factor activity
F6W81_RS08130	COG0839	Belongs to the complex I subunit 6 family
F6W81_RS08140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F6W81_RS08145	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F6W81_RS08160	COG2153	protein acetylation
F6W81_RS08165	COG1169	isochorismate synthase
F6W81_RS08190	COG0318	PFAM AMP-dependent synthetase and ligase
F6W81_RS08200	COG5464	transposase or invertase
F6W81_RS08215	COG1414	Transcriptional regulator
F6W81_RS08225	COG2271	Major facilitator Superfamily
F6W81_RS08235	COG0247	lactate metabolic process
F6W81_RS08245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F6W81_RS08255	COG0584	glycerophosphoryl diester phosphodiesterase
F6W81_RS08260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F6W81_RS08285	COG2205	protein histidine kinase activity
F6W81_RS08285	COG0784	Response regulator, receiver
F6W81_RS08295	COG2198	Histidine kinase
F6W81_RS08295	COG0642	Histidine kinase
F6W81_RS08310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F6W81_RS08310	COG2169	Transcriptional regulator
F6W81_RS08315	COG3145	DNA-N1-methyladenine dioxygenase activity
F6W81_RS08320	COG4615	Cyclic peptide transporter
F6W81_RS08325	COG2239	Acts as a magnesium transporter
F6W81_RS08330	COG0659	secondary active sulfate transmembrane transporter activity
F6W81_RS08345	COG0628	permease
F6W81_RS08370	COG1349	DNA-binding transcription factor activity
F6W81_RS08375	COG0494	nUDIX hydrolase
F6W81_RS08395	COG1061	Type III restriction enzyme res subunit
F6W81_RS08400	COG1187	pseudouridine synthase activity
F6W81_RS08405	COG2814	Major facilitator Superfamily
F6W81_RS08415	COG4172	Belongs to the ABC transporter superfamily
F6W81_RS08420	COG4239	(ABC) transporter, permease
F6W81_RS08425	COG4174	ABC transporter (Permease)
F6W81_RS08430	COG4166	transmembrane transport
F6W81_RS08435	COG2200	EAL domain
F6W81_RS08440	COG0791	NLP P60 protein
F6W81_RS08445	COG0671	phosphoesterase, PA-phosphatase related
F6W81_RS08450	COG0523	cobalamin synthesis protein
F6W81_RS08455	COG0246	Mannitol dehydrogenase
F6W81_RS08460	COG1312	Catalyzes the dehydration of D-mannonate
F6W81_RS08485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS08485	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS08490	COG1105	Belongs to the carbohydrate kinase PfkB family
F6W81_RS08495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6W81_RS08495	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F6W81_RS08495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6W81_RS08505	COG2855	membrane
F6W81_RS08510	COG0583	DNA-binding transcription factor activity
F6W81_RS08515	COG0833	amino acid
F6W81_RS08525	COG4771	TonB-dependent receptor
F6W81_RS08540	COG2311	Membrane
F6W81_RS08555	COG1129	ABC transporter
F6W81_RS08565	COG2949	membrane
F6W81_RS08575	COG1346	cytolysis
F6W81_RS08585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F6W81_RS08590	COG3659	wide pore channel activity
F6W81_RS08605	COG2723	6-phospho-beta-galactosidase activity
F6W81_RS08610	COG1538	Outer membrane efflux protein
F6W81_RS08615	COG0586	Pfam SNARE associated Golgi protein
F6W81_RS08625	COG1686	Belongs to the peptidase S11 family
F6W81_RS08635	COG0277	FAD linked oxidase domain protein
F6W81_RS08640	COG1472	Belongs to the glycosyl hydrolase 3 family
F6W81_RS08645	COG1732	Glycine betaine
F6W81_RS08650	COG1174	glycine betaine transport
F6W81_RS08655	COG1125	glycine betaine transport
F6W81_RS08660	COG1174	glycine betaine transport
F6W81_RS08670	COG3275	phosphorelay sensor kinase activity
F6W81_RS08680	COG4807	Protein conserved in bacteria
F6W81_RS08700	COG5455	response to cobalt ion
F6W81_RS08705	COG0583	DNA-binding transcription factor activity
F6W81_RS08710	COG2252	PERMEase
F6W81_RS08720	COG0583	DNA-binding transcription factor activity
F6W81_RS08735	COG0351	phosphomethylpyrimidine kinase
F6W81_RS08740	COG1830	Aldolase
F6W81_RS08775	COG1070	Carbohydrate kinase
F6W81_RS08785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F6W81_RS08790	COG4948	Mandelate Racemase Muconate Lactonizing
F6W81_RS08795	COG0747	negative chemotaxis
F6W81_RS08800	COG0601	transmembrane transport
F6W81_RS08805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6W81_RS08810	COG0444	Belongs to the ABC transporter superfamily
F6W81_RS08815	COG4608	Belongs to the ABC transporter superfamily
F6W81_RS08825	COG0826	peptidase U32
F6W81_RS08830	COG0745	RESPONSE REGULATOR receiver
F6W81_RS08835	COG2205	protein histidine kinase activity
F6W81_RS08860	COG1301	dicarboxylic acid transport
F6W81_RS08880	COG5002	protein histidine kinase activity
F6W81_RS08885	COG0443	Heat shock 70 kDa protein
F6W81_RS08890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F6W81_RS08905	COG2982	Protein involved in outer membrane biogenesis
F6W81_RS08910	COG1253	flavin adenine dinucleotide binding
F6W81_RS08955	COG0463	Glycosyl transferase, family 2
F6W81_RS08970	COG2244	polysaccharide biosynthetic process
F6W81_RS08980	COG1088	dTDP-glucose 4,6-dehydratase activity
F6W81_RS09020	COG1088	dTDP-glucose 4,6-dehydratase activity
F6W81_RS09045	COG3039	Transposase
F6W81_RS09095	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F6W81_RS09125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F6W81_RS09130	COG0583	DNA-binding transcription factor activity
F6W81_RS09140	COG0531	amino acid
F6W81_RS09145	COG0640	Transcriptional regulator
F6W81_RS09150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F6W81_RS09155	COG2925	Exonuclease
F6W81_RS09170	COG3344	reverse transcriptase
F6W81_RS09180	COG1289	transmembrane transporter activity
F6W81_RS09200	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F6W81_RS09210	COG1942	4-Oxalocrotonate Tautomerase
F6W81_RS09215	COG0583	DNA-binding transcription factor activity
F6W81_RS09220	COG0095	Lipoate-protein ligase
F6W81_RS09225	COG0477	Major facilitator Superfamily
F6W81_RS09240	COG3300	MHYT domain
F6W81_RS09240	COG5001	Diguanylate cyclase
F6W81_RS09245	COG3615	Tellurite resistance protein tehB
F6W81_RS09270	COG3706	GGDEF domain
F6W81_RS09330	COG2003	Belongs to the UPF0758 family
F6W81_RS09400	COG3504	Conjugal transfer protein
F6W81_RS09470	COG4771	TonB-dependent receptor
F6W81_RS09475	COG1021	2,3-dihydroxybenzoate-AMP ligase
F6W81_RS09495	COG2226	methyltransferase
F6W81_RS09495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F6W81_RS09495	COG3433	isochorismatase activity
F6W81_RS09510	COG1132	(ABC) transporter
F6W81_RS09515	COG2814	Major facilitator Superfamily
F6W81_RS09520	COG1169	isochorismate synthase
F6W81_RS09525	COG0582	viral genome integration into host DNA
F6W81_RS09535	COG0534	Mate efflux family protein
F6W81_RS09545	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F6W81_RS09565	COG0604	alcohol dehydrogenase
F6W81_RS09570	COG1309	transcriptional regulator
F6W81_RS09575	COG0025	NhaP-type Na H and K H
F6W81_RS09620	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F6W81_RS09635	COG1418	mRNA catabolic process
F6W81_RS09640	COG0270	DNA (cytosine-5-)-methyltransferase activity
F6W81_RS09645	COG3727	T/G mismatch-specific endonuclease activity
F6W81_RS09650	COG0697	spore germination
F6W81_RS09655	COG2354	Protein conserved in bacteria
F6W81_RS09685	COG0366	Alpha amylase catalytic
F6W81_RS09690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6W81_RS09700	COG0765	amino acid transport
F6W81_RS09705	COG1126	abc transporter atp-binding protein
F6W81_RS09710	COG2197	response regulator
F6W81_RS09720	COG2197	response regulator
F6W81_RS09760	COG3318	Belongs to the UPF0149 family
F6W81_RS09760	COG3012	SEC-C Motif Domain Protein
F6W81_RS09765	COG0814	amino acid
F6W81_RS09775	COG1528	Iron-storage protein
F6W81_RS09790	COG0477	Major facilitator Superfamily
F6W81_RS09800	COG2211	Major facilitator Superfamily
F6W81_RS09810	COG1528	Iron-storage protein
F6W81_RS09820	COG1879	ABC-type sugar transport system periplasmic component
F6W81_RS09830	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS09855	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F6W81_RS09865	COG3102	Protein conserved in bacteria
F6W81_RS09885	COG3788	relative of glutathione S-transferase, MAPEG superfamily
F6W81_RS09890	COG1801	Protein of unknown function DUF72
F6W81_RS09895	COG1335	isochorismatase
F6W81_RS09905	COG0494	nUDIX hydrolase
F6W81_RS09930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F6W81_RS09940	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
F6W81_RS09945	COG0739	heme binding
F6W81_RS09950	COG1560	Kdo2-lipid A biosynthetic process
F6W81_RS09960	COG1737	Transcriptional regulator
F6W81_RS09975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F6W81_RS09980	COG0129	dihydroxy-acid dehydratase activity
F6W81_RS09985	COG0800	Aldolase
F6W81_RS09995	COG3141	response to X-ray
F6W81_RS10000	COG2979	Protein of unknown function (DUF533)
F6W81_RS10005	COG1770	oligopeptidase
F6W81_RS10010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F6W81_RS10020	COG2372	response to copper ion
F6W81_RS10025	COG1276	copper resistance
F6W81_RS10045	COG2990	Protein conserved in bacteria
F6W81_RS10070	COG3008	intermembrane lipid transfer
F6W81_RS10075	COG2995	paraquat-inducible protein a
F6W81_RS10080	COG1956	GAF domain-containing protein
F6W81_RS10100	COG2814	Major facilitator Superfamily
F6W81_RS10105	COG1414	Transcriptional regulator
F6W81_RS10155	COG0768	penicillin binding
F6W81_RS10160	COG2226	methyltransferase
F6W81_RS10175	COG3716	PTS system mannose fructose sorbose family IID component
F6W81_RS10180	COG3715	PTS system
F6W81_RS10185	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6W81_RS10185	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS10190	COG1253	flavin adenine dinucleotide binding
F6W81_RS10195	COG2200	EAL domain
F6W81_RS10200	COG1760	l-serine dehydratase
F6W81_RS10220	COG0251	oxidation-reduction process
F6W81_RS10225	COG1199	ATP-dependent helicase activity
F6W81_RS10235	COG3065	identical protein binding
F6W81_RS10245	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F6W81_RS10255	COG2894	cell division
F6W81_RS10270	COG0179	Fumarylacetoacetate (FAA) hydrolase
F6W81_RS10300	COG2719	SpoVR family
F6W81_RS10320	COG1619	proteins homologs of microcin C7 resistance protein MccF
F6W81_RS10330	COG4774	siderophore transport
F6W81_RS10345	COG2308	Evidence 4 Homologs of previously reported genes of
F6W81_RS10385	COG0583	DNA-binding transcription factor activity
F6W81_RS10390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F6W81_RS10405	COG1882	Formate acetyltransferase
F6W81_RS10490	COG0012	GTP binding
F6W81_RS10510	COG0659	secondary active sulfate transmembrane transporter activity
F6W81_RS10540	COG2890	protein-(glutamine-N5) methyltransferase activity
F6W81_RS10560	COG0387	Pfam Sodium calcium exchanger
F6W81_RS10565	COG4572	Cation transport regulator
F6W81_RS10570	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
F6W81_RS10580	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F6W81_RS10585	COG3707	response regulator
F6W81_RS10590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F6W81_RS10600	COG1116	anion transmembrane transporter activity
F6W81_RS10605	COG2146	nitrite reductase [NAD(P)H] activity
F6W81_RS10605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F6W81_RS10610	COG0243	molybdopterin cofactor binding
F6W81_RS10615	COG4932	domain protein
F6W81_RS10620	COG2197	response regulator
F6W81_RS10625	COG3850	Histidine kinase
F6W81_RS10630	COG2223	nitrite transmembrane transporter activity
F6W81_RS10635	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F6W81_RS10640	COG1140	nitrate reductase beta subunit
F6W81_RS10645	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F6W81_RS10650	COG2181	nitrate reductase activity
F6W81_RS10660	COG1522	sequence-specific DNA binding
F6W81_RS10695	COG0788	formyltetrahydrofolate deformylase activity
F6W81_RS10705	COG1752	Esterase of the alpha-beta hydrolase superfamily
F6W81_RS10710	COG0745	RESPONSE REGULATOR receiver
F6W81_RS10715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F6W81_RS10720	COG2916	Histone family protein nucleoid-structuring protein H-NS
F6W81_RS10725	COG1435	thymidine kinase activity
F6W81_RS10730	COG1454	alcohol dehydrogenase
F6W81_RS10730	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS10740	COG2095	MarC family integral membrane protein
F6W81_RS10745	COG4166	transmembrane transport
F6W81_RS10750	COG0601	transmembrane transport
F6W81_RS10755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6W81_RS10760	COG0444	Belongs to the ABC transporter superfamily
F6W81_RS10770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F6W81_RS10790	COG2353	YceI-like domain
F6W81_RS10795	COG2350	Protein conserved in bacteria
F6W81_RS10805	COG3001	Fructosamine kinase
F6W81_RS10815	COG1105	Belongs to the carbohydrate kinase PfkB family
F6W81_RS10820	COG3137	Salt-induced outer membrane protein
F6W81_RS10860	COG0072	phenylalanine-tRNA ligase activity
F6W81_RS10860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F6W81_RS10880	COG0583	DNA-binding transcription factor activity
F6W81_RS10900	COG0386	Belongs to the glutathione peroxidase family
F6W81_RS10910	COG0791	NLP P60 protein
F6W81_RS10920	COG4256	Hemin uptake protein
F6W81_RS10925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F6W81_RS10935	COG0574	Belongs to the PEP-utilizing enzyme family
F6W81_RS10935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F6W81_RS10945	COG0628	permease
F6W81_RS10950	COG0247	lactate metabolic process
F6W81_RS10950	COG0277	FAD linked oxidase domain protein
F6W81_RS10955	COG2050	protein possibly involved in aromatic compounds catabolism
F6W81_RS10960	COG2261	transglycosylase associated protein
F6W81_RS10990	COG1120	ATPase activity
F6W81_RS10995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6W81_RS11005	COG0583	DNA-binding transcription factor activity
F6W81_RS11030	COG1304	FMN binding
F6W81_RS11035	COG1309	transcriptional regulator
F6W81_RS11050	COG0316	Belongs to the HesB IscA family
F6W81_RS11055	COG0719	Fe-S assembly protein
F6W81_RS11060	COG0396	ATPase activity
F6W81_RS11065	COG0719	Fe-S assembly protein
F6W81_RS11080	COG1376	ErfK ybiS ycfS ynhG family protein
F6W81_RS11105	COG1309	transcriptional regulator
F6W81_RS11110	COG3185	4-Hydroxyphenylpyruvate dioxygenase
F6W81_RS11110	COG1082	Xylose isomerase domain protein TIM barrel
F6W81_RS11115	COG2271	Major facilitator Superfamily
F6W81_RS11120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F6W81_RS11130	COG1120	ATPase activity
F6W81_RS11135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6W81_RS11140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F6W81_RS11145	COG1414	Transcriptional regulator
F6W81_RS11180	COG2814	Major facilitator Superfamily
F6W81_RS11200	COG0583	DNA-binding transcription factor activity
F6W81_RS11205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6W81_RS11225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F6W81_RS11230	COG1116	anion transmembrane transporter activity
F6W81_RS11235	COG4774	siderophore transport
F6W81_RS11240	COG1120	ATPase activity
F6W81_RS11245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6W81_RS11250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6W81_RS11270	COG0765	amino acid transport
F6W81_RS11275	COG1126	abc transporter atp-binding protein
F6W81_RS11305	COG1473	amidohydrolase
F6W81_RS11310	COG3383	formate dehydrogenase (NAD+) activity
F6W81_RS11315	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F6W81_RS11330	COG1175	transmembrane transport
F6W81_RS11360	COG4133	protoheme IX ABC transporter activity
F6W81_RS11365	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F6W81_RS11370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F6W81_RS11385	COG1138	Cytochrome C-type biogenesis protein
F6W81_RS11390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F6W81_RS11395	COG4235	cytochrome complex assembly
F6W81_RS11395	COG3088	subunit of a heme lyase
F6W81_RS11435	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
F6W81_RS11480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6W81_RS11515	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS11520	COG2610	gluconate transmembrane transporter activity
F6W81_RS11525	COG1250	3-hydroxyacyl-CoA dehydrogenase
F6W81_RS11535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F6W81_RS11545	COG0583	DNA-binding transcription factor activity
F6W81_RS11570	COG0277	FAD linked oxidase domain protein
F6W81_RS11575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F6W81_RS11600	COG0402	S-adenosylhomocysteine deaminase activity
F6W81_RS11655	COG0604	alcohol dehydrogenase
F6W81_RS11655	COG3321	synthase
F6W81_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS11685	COG4608	Belongs to the ABC transporter superfamily
F6W81_RS11690	COG0444	Belongs to the ABC transporter superfamily
F6W81_RS11715	COG0346	lactoylglutathione lyase activity
F6W81_RS11720	COG1349	DNA-binding transcription factor activity
F6W81_RS11750	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
F6W81_RS11805	COG0307	riboflavin synthase, alpha
F6W81_RS11810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F6W81_RS11815	COG2814	Major facilitator Superfamily
F6W81_RS11820	COG0583	DNA-binding transcription factor activity
F6W81_RS11835	COG2814	Major facilitator Superfamily
F6W81_RS11850	COG0791	NLP P60 protein
F6W81_RS11855	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F6W81_RS11865	COG0346	lactoylglutathione lyase activity
F6W81_RS11870	COG1902	pentaerythritol trinitrate reductase activity
F6W81_RS11875	COG1309	transcriptional regulator
F6W81_RS11880	COG3313	Fe-S protein
F6W81_RS11885	COG4989	oxidoreductase activity
F6W81_RS11890	COG2032	superoxide dismutase activity
F6W81_RS11895	COG1289	transmembrane transporter activity
F6W81_RS11900	COG1566	PFAM secretion protein HlyD family protein
F6W81_RS11915	COG3706	GGDEF domain
F6W81_RS11930	COG3895	Periplasmic Protein
F6W81_RS11945	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
F6W81_RS11950	COG0625	glutathione transferase activity
F6W81_RS11965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F6W81_RS11975	COG4659	FMN binding
F6W81_RS12010	COG2723	6-phospho-beta-galactosidase activity
F6W81_RS12020	COG0673	inositol 2-dehydrogenase activity
F6W81_RS12030	COG2814	Major facilitator Superfamily
F6W81_RS12050	COG3038	cytochrome b561
F6W81_RS12070	COG0583	DNA-binding transcription factor activity
F6W81_RS12075	COG3485	protocatechuate 3,4-dioxygenase
F6W81_RS12080	COG3485	protocatechuate 3,4-dioxygenase
F6W81_RS12085	COG5383	Protein conserved in bacteria
F6W81_RS12090	COG2272	Belongs to the type-B carboxylesterase lipase family
F6W81_RS12105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F6W81_RS12110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F6W81_RS12115	COG1275	C4-dicarboxylate transporter malic acid transport protein
F6W81_RS12120	COG0500	methyltransferase
F6W81_RS12135	COG3708	Transcriptional regulator
F6W81_RS12135	COG2207	Transcriptional regulator
F6W81_RS12140	COG3135	benzoate transporter
F6W81_RS12145	COG1396	sequence-specific DNA binding
F6W81_RS12155	COG0826	peptidase U32
F6W81_RS12175	COG1294	oxidase, subunit
F6W81_RS12180	COG1271	oxidase subunit
F6W81_RS12185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F6W81_RS12190	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F6W81_RS12195	COG3842	ATPase activity
F6W81_RS12200	COG1176	ABC-type spermidine putrescine transport system, permease component I
F6W81_RS12205	COG1177	transmembrane transport
F6W81_RS12210	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS12245	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS12250	COG0747	negative chemotaxis
F6W81_RS12260	COG3238	Protein conserved in bacteria
F6W81_RS12265	COG1247	-acetyltransferase
F6W81_RS12275	COG2130	NADP-dependent
F6W81_RS12290	COG3691	Protein conserved in bacteria
F6W81_RS12295	COG1228	amidohydrolase
F6W81_RS12300	COG4772	TonB-dependent receptor
F6W81_RS12325	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F6W81_RS12330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6W81_RS12335	COG1473	amidohydrolase
F6W81_RS12340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6W81_RS12345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6W81_RS12355	COG0765	amino acid transport
F6W81_RS12360	COG1126	abc transporter atp-binding protein
F6W81_RS12370	COG0625	glutathione transferase activity
F6W81_RS12400	COG2211	Major facilitator Superfamily
F6W81_RS12415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F6W81_RS12420	COG3842	ATPase activity
F6W81_RS12425	COG1840	ABC-type Fe3 transport system, periplasmic component
F6W81_RS12430	COG1178	ABC-type Fe3 transport system permease component
F6W81_RS12435	COG2162	N-hydroxyarylamine O-acetyltransferase activity
F6W81_RS12440	COG2181	nitrate reductase activity
F6W81_RS12445	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F6W81_RS12450	COG1140	nitrate reductase beta subunit
F6W81_RS12455	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F6W81_RS12475	COG1414	Transcriptional regulator
F6W81_RS12480	COG4948	Mandelate Racemase Muconate Lactonizing
F6W81_RS12485	COG4829	muconolactone delta-isomerase
F6W81_RS12490	COG3485	protocatechuate 3,4-dioxygenase
F6W81_RS12500	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F6W81_RS12525	COG0437	4 iron, 4 sulfur cluster binding
F6W81_RS12530	COG2864	formate dehydrogenase
F6W81_RS12545	COG2326	polyphosphate kinase activity
F6W81_RS12555	COG2814	Major facilitator Superfamily
F6W81_RS12565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6W81_RS12575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6W81_RS12585	COG0747	negative chemotaxis
F6W81_RS12590	COG1064	alcohol dehydrogenase
F6W81_RS12605	COG0488	(ABC) transporter
F6W81_RS12645	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS12650	COG3729	General stress protein
F6W81_RS12665	COG3685	Protein conserved in bacteria
F6W81_RS12675	COG0366	Alpha amylase catalytic
F6W81_RS12685	COG2323	membrane
F6W81_RS12695	COG3111	PFAM Bacterial OB fold (BOF) protein
F6W81_RS12700	COG1764	response to oxidative stress
F6W81_RS12725	COG3781	membrane
F6W81_RS12730	COG0243	molybdopterin cofactor binding
F6W81_RS12735	COG0583	DNA-binding transcription factor activity
F6W81_RS12740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6W81_RS12765	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6W81_RS12770	COG1447	Phosphotransferase system cellobiose-specific component IIA
F6W81_RS12775	COG2814	Major facilitator Superfamily
F6W81_RS12785	COG1285	pathogenesis
F6W81_RS12790	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F6W81_RS12800	COG0583	DNA-binding transcription factor activity
F6W81_RS12820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F6W81_RS12820	COG0519	Catalyzes the synthesis of GMP from XMP
F6W81_RS12860	COG0596	Alpha beta hydrolase
F6W81_RS12870	COG2205	protein histidine kinase activity
F6W81_RS12885	COG0076	glutamate decarboxylase activity
F6W81_RS12890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F6W81_RS12895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F6W81_RS12900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F6W81_RS12905	COG1116	anion transmembrane transporter activity
F6W81_RS12910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F6W81_RS12920	COG0673	inositol 2-dehydrogenase activity
F6W81_RS12930	COG1609	Transcriptional regulator
F6W81_RS12935	COG3706	GGDEF domain
F6W81_RS12940	COG0402	S-adenosylhomocysteine deaminase activity
F6W81_RS12945	COG1953	Uracil, thiamine, allantoin
F6W81_RS12980	COG0406	alpha-ribazole phosphatase activity
F6W81_RS12990	COG1335	isochorismatase
F6W81_RS13030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F6W81_RS13100	COG0765	amino acid transport
F6W81_RS13110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F6W81_RS13120	COG2070	2-Nitropropane dioxygenase
F6W81_RS13125	COG0583	DNA-binding transcription factor activity
F6W81_RS13135	COG1902	pentaerythritol trinitrate reductase activity
F6W81_RS13140	COG4529	Protein conserved in bacteria
F6W81_RS13145	COG0477	Major facilitator Superfamily
F6W81_RS13175	COG2223	nitrite transmembrane transporter activity
F6W81_RS13185	COG1609	Transcriptional regulator
F6W81_RS13190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS13200	COG3037	sugar-specific permease SgaT UlaA
F6W81_RS13205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F6W81_RS13215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6W81_RS13220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6W81_RS13220	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F6W81_RS13220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F6W81_RS13235	COG0583	DNA-binding transcription factor activity
F6W81_RS13240	COG0583	DNA-binding transcription factor activity
F6W81_RS13245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F6W81_RS13255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F6W81_RS13270	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS13280	COG1609	Transcriptional regulator
F6W81_RS13310	COG1652	LysM domain
F6W81_RS13325	COG0426	domain, Protein
F6W81_RS13325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F6W81_RS13350	COG0456	acetyltransferase
F6W81_RS13350	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F6W81_RS13360	COG0667	Aldo Keto reductase
F6W81_RS13365	COG0667	Aldo Keto reductase
F6W81_RS13375	COG0667	Aldo Keto reductase
F6W81_RS13390	COG4977	sequence-specific DNA binding
F6W81_RS13415	COG4977	sequence-specific DNA binding
F6W81_RS13420	COG1349	DNA-binding transcription factor activity
F6W81_RS13435	COG1349	DNA-binding transcription factor activity
F6W81_RS13440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F6W81_RS13445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6W81_RS13450	COG0738	Major facilitator superfamily
F6W81_RS13495	COG1929	Belongs to the glycerate kinase type-1 family
F6W81_RS13500	COG3835	regulator
F6W81_RS13520	COG2186	Transcriptional regulator
F6W81_RS13525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6W81_RS13525	COG1263	PTS System
F6W81_RS13535	COG2814	Major facilitator Superfamily
F6W81_RS13540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS13540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS13550	COG2819	hydrolase of the alpha beta superfamily
F6W81_RS13555	COG3300	MHYT domain
F6W81_RS13555	COG5001	Diguanylate cyclase
F6W81_RS13590	COG3188	usher protein
F6W81_RS13600	COG1649	PFAM Uncharacterised BCR, COG1649
F6W81_RS13605	COG3550	peptidyl-serine autophosphorylation
F6W81_RS13610	COG1396	sequence-specific DNA binding
F6W81_RS13615	COG2351	hydroxyisourate hydrolase activity
F6W81_RS13620	COG3195	allantoin biosynthetic process
F6W81_RS13620	COG3648	Uricase
F6W81_RS13625	COG2233	PERMEase
F6W81_RS13655	COG2207	Transcriptional regulator
F6W81_RS13670	COG4628	conserved protein (DUF2132)
F6W81_RS13690	COG2011	ABC-type metal ion transport system permease component
F6W81_RS13695	COG2070	2-Nitropropane dioxygenase
F6W81_RS13705	COG0477	Major facilitator Superfamily
F6W81_RS13785	COG2199	diguanylate cyclase activity
F6W81_RS13800	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS13805	COG0583	DNA-binding transcription factor activity
F6W81_RS13815	COG0039	L-malate dehydrogenase activity
F6W81_RS13820	COG1349	DNA-binding transcription factor activity
F6W81_RS13825	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F6W81_RS13830	COG3395	kinase activity
F6W81_RS13840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F6W81_RS13855	COG2731	YhcH YjgK YiaL family protein
F6W81_RS13860	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS13885	COG4977	sequence-specific DNA binding
F6W81_RS13895	COG0697	spore germination
F6W81_RS13900	COG2814	Major facilitator Superfamily
F6W81_RS13910	COG0410	ABC transporter
F6W81_RS13915	COG1129	ABC transporter
F6W81_RS13930	COG0683	leucine binding
F6W81_RS13935	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F6W81_RS13970	COG2223	nitrite transmembrane transporter activity
F6W81_RS13975	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F6W81_RS13990	COG1349	DNA-binding transcription factor activity
F6W81_RS13995	COG2084	Dehydrogenase
F6W81_RS14000	COG3395	kinase activity
F6W81_RS14005	COG0235	Class ii aldolase
F6W81_RS14010	COG3622	Belongs to the hyi family
F6W81_RS14015	COG2610	gluconate transmembrane transporter activity
F6W81_RS14020	COG3708	Transcriptional regulator
F6W81_RS14020	COG2207	Transcriptional regulator
F6W81_RS14040	COG2200	EAL domain
F6W81_RS14045	COG1546	Belongs to the CinA family
F6W81_RS14050	COG0071	Belongs to the small heat shock protein (HSP20) family
F6W81_RS14060	COG2197	response regulator
F6W81_RS14070	COG2135	peptidase activity
F6W81_RS14075	COG2207	Transcriptional regulator
F6W81_RS14090	COG4221	oxidoreductase activity
F6W81_RS14095	COG1802	Transcriptional regulator
F6W81_RS14100	COG0589	response to stress
F6W81_RS14105	COG0246	Mannitol dehydrogenase
F6W81_RS14110	COG2271	Major facilitator Superfamily
F6W81_RS14125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F6W81_RS14140	COG0243	molybdopterin cofactor binding
F6W81_RS14145	COG0437	4 iron, 4 sulfur cluster binding
F6W81_RS14150	COG3302	dmso reductase anchor subunit
F6W81_RS14165	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F6W81_RS14170	COG1940	carbohydrate kinase activity
F6W81_RS14175	COG0583	DNA-binding transcription factor activity
F6W81_RS14180	COG2814	Major facilitator Superfamily
F6W81_RS14185	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
F6W81_RS14195	COG3591	Belongs to the peptidase S1B family
F6W81_RS14215	COG0628	permease
F6W81_RS14245	COG0679	Auxin Efflux Carrier
F6W81_RS14255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F6W81_RS14280	COG3290	protein histidine kinase activity
F6W81_RS14285	COG4565	transcriptional regulatory protein
F6W81_RS14305	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F6W81_RS14305	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F6W81_RS14315	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F6W81_RS14320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F6W81_RS14330	COG0183	Belongs to the thiolase family
F6W81_RS14335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F6W81_RS14345	COG1414	Transcriptional regulator
F6W81_RS14350	COG2840	Smr protein MutS2
F6W81_RS14355	COG0583	DNA-binding transcription factor activity
F6W81_RS14365	COG1473	amidohydrolase
F6W81_RS14370	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
F6W81_RS14385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F6W81_RS14400	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F6W81_RS14405	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F6W81_RS14425	COG0531	amino acid
F6W81_RS14435	COG3136	membrane protein required for alginate biosynthesis
F6W81_RS14440	COG0745	RESPONSE REGULATOR receiver
F6W81_RS14450	COG2205	protein histidine kinase activity
F6W81_RS14460	COG0114	fumarate hydratase activity
F6W81_RS14465	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F6W81_RS14465	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F6W81_RS14470	COG1482	cell wall glycoprotein biosynthetic process
F6W81_RS14475	COG5339	Protein conserved in bacteria
F6W81_RS14480	COG1609	Transcriptional regulator
F6W81_RS14485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6W81_RS14485	COG1263	PTS System
F6W81_RS14490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F6W81_RS14515	COG2391	methyltransferase activity
F6W81_RS14520	COG0425	Belongs to the sulfur carrier protein TusA family
F6W81_RS14525	COG5562	phage envelope protein
F6W81_RS14530	COG0401	homolog of Blt101
F6W81_RS14535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F6W81_RS14540	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS14545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F6W81_RS14550	COG0477	Major facilitator Superfamily
F6W81_RS14555	COG1113	amino acid transport
F6W81_RS14560	COG2988	succinylglutamate desuccinylase activity
F6W81_RS14565	COG3724	N-succinylarginine dihydrolase activity
F6W81_RS14570	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS14575	COG3138	arginine N-succinyltransferase
F6W81_RS14580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F6W81_RS14585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F6W81_RS14590	COG0667	Aldo Keto reductase
F6W81_RS14595	COG0583	DNA-binding transcription factor activity
F6W81_RS14620	COG4122	O-methyltransferase activity
F6W81_RS14625	COG1643	Atp-dependent helicase
F6W81_RS14640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F6W81_RS14645	COG3327	negative regulation of DNA-templated transcription, initiation
F6W81_RS14650	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
F6W81_RS14655	COG0183	Belongs to the thiolase family
F6W81_RS14660	COG2050	protein possibly involved in aromatic compounds catabolism
F6W81_RS14665	COG1250	3-hydroxyacyl-CoA dehydrogenase
F6W81_RS14670	COG1024	Enoyl-CoA hydratase
F6W81_RS14675	COG1024	Enoyl-CoA hydratase
F6W81_RS14680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F6W81_RS14685	COG2151	metal-sulfur cluster biosynthetic enzyme
F6W81_RS14690	COG3396	Phenylacetate-CoA oxygenase
F6W81_RS14695	COG3460	Phenylacetate-CoA oxygenase
F6W81_RS14700	COG3396	Phenylacetate-CoA oxygenase
F6W81_RS14705	COG2030	dehydratase
F6W81_RS14705	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS14725	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS14730	COG2207	Transcriptional regulator
F6W81_RS14735	COG3784	Protein of unknown function (DUF1318)
F6W81_RS14745	COG2911	Protein conserved in bacteria
F6W81_RS14750	COG0586	Pfam SNARE associated Golgi protein
F6W81_RS14755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F6W81_RS14760	COG3187	Heat shock protein
F6W81_RS14765	COG3042	response to heat
F6W81_RS14775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F6W81_RS14775	COG0674	pyruvate-flavodoxin oxidoreductase activity
F6W81_RS14775	COG1013	pyruvate-flavodoxin oxidoreductase activity
F6W81_RS14775	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
F6W81_RS14780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F6W81_RS14790	COG0589	response to stress
F6W81_RS14800	COG0513	Belongs to the DEAD box helicase family
F6W81_RS14815	COG1349	DNA-binding transcription factor activity
F6W81_RS14820	COG0673	inositol 2-dehydrogenase activity
F6W81_RS14835	COG1113	amino acid transport
F6W81_RS14840	COG1522	sequence-specific DNA binding
F6W81_RS14850	COG1448	Aminotransferase
F6W81_RS14855	COG2011	ABC-type metal ion transport system permease component
F6W81_RS14870	COG0436	Aminotransferase
F6W81_RS14875	COG0604	alcohol dehydrogenase
F6W81_RS14900	COG0583	DNA-binding transcription factor activity
F6W81_RS14920	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS14925	COG1309	transcriptional regulator
F6W81_RS14930	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS15025	COG2885	chlorophyll binding
F6W81_RS15155	COG0741	lytic transglycosylase activity
F6W81_RS15155	COG1196	nuclear chromosome segregation
F6W81_RS15155	COG0739	heme binding
F6W81_RS15225	COG3567	Phage-associated protein, HI1409 family
F6W81_RS15230	COG1783	phage Terminase large subunit
F6W81_RS15255	COG3772	lysozyme
F6W81_RS15265	COG0484	heat shock protein binding
F6W81_RS15370	COG0582	viral genome integration into host DNA
F6W81_RS15375	COG0693	protein deglycase activity
F6W81_RS15395	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS15400	COG0583	DNA-binding transcription factor activity
F6W81_RS15420	COG0656	L-ascorbic acid biosynthetic process
F6W81_RS15450	COG4166	transmembrane transport
F6W81_RS15455	COG2866	Carboxypeptidase
F6W81_RS15460	COG4948	Mandelate Racemase Muconate Lactonizing
F6W81_RS15465	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F6W81_RS15470	COG3180	Ammonia monooxygenase
F6W81_RS15480	COG1486	melibiose metabolic process
F6W81_RS15485	COG0583	DNA-binding transcription factor activity
F6W81_RS15495	COG3106	COG3106 Predicted ATPase
F6W81_RS15505	COG1983	PspC domain protein
F6W81_RS15515	COG1842	Phage shock protein A
F6W81_RS15520	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F6W81_RS15530	COG1473	amidohydrolase
F6W81_RS15545	COG0702	epimerase
F6W81_RS15560	COG2135	peptidase activity
F6W81_RS15570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F6W81_RS15575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F6W81_RS15580	COG3344	reverse transcriptase
F6W81_RS15640	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F6W81_RS15760	COG4171	peptide transport system, permease
F6W81_RS15775	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F6W81_RS15785	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F6W81_RS15790	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F6W81_RS15790	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F6W81_RS15805	COG1349	DNA-binding transcription factor activity
F6W81_RS15815	COG0023	Translation Initiation Factor
F6W81_RS15825	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F6W81_RS15830	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
F6W81_RS15835	COG0671	phosphoesterase, PA-phosphatase related
F6W81_RS15845	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F6W81_RS15870	COG0616	signal peptide processing
F6W81_RS15880	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS15885	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
F6W81_RS15895	COG0583	DNA-binding transcription factor activity
F6W81_RS15905	COG0009	L-threonylcarbamoyladenylate synthase
F6W81_RS15915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F6W81_RS15920	COG0512	Glutamine amidotransferase of anthranilate synthase
F6W81_RS15920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F6W81_RS15925	COG0134	indole-3-glycerol-phosphate synthase activity
F6W81_RS15925	COG0135	phosphoribosylanthranilate isomerase activity
F6W81_RS15980	COG4774	siderophore transport
F6W81_RS15990	COG3047	cAMP biosynthetic process
F6W81_RS15995	COG0727	PFAM Uncharacterised protein family (UPF0153)
F6W81_RS16025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F6W81_RS16030	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS16035	COG1988	membrane-bound metal-dependent
F6W81_RS16040	COG1823	symporter activity
F6W81_RS16050	COG0753	catalase activity
F6W81_RS16060	COG1486	melibiose metabolic process
F6W81_RS16065	COG2169	Transcriptional regulator
F6W81_RS16065	COG1917	Cupin 2, conserved barrel domain protein
F6W81_RS16070	COG1447	Phosphotransferase system cellobiose-specific component IIA
F6W81_RS16075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6W81_RS16080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6W81_RS16085	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F6W81_RS16095	COG0322	excinuclease ABC activity
F6W81_RS16100	COG3678	ATP-independent chaperone mediated protein folding
F6W81_RS16110	COG3724	N-succinylarginine dihydrolase activity
F6W81_RS16120	COG3138	arginine N-succinyltransferase
F6W81_RS16130	COG0708	Exodeoxyribonuclease III
F6W81_RS16135	COG0398	Pfam SNARE associated Golgi protein
F6W81_RS16140	COG0398	Pfam SNARE associated Golgi protein
F6W81_RS16145	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F6W81_RS16150	COG4134	Bacterial extracellular solute-binding protein
F6W81_RS16155	COG4135	transport system, permease component
F6W81_RS16160	COG4136	ATPase activity
F6W81_RS16165	COG2897	thiosulfate sulfurtransferase activity
F6W81_RS16170	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F6W81_RS16175	COG0494	nUDIX hydrolase
F6W81_RS16180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F6W81_RS16185	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS16185	COG0604	alcohol dehydrogenase
F6W81_RS16185	COG3321	synthase
F6W81_RS16190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F6W81_RS16195	COG0709	Synthesizes selenophosphate from selenide and ATP
F6W81_RS16210	COG0778	Nitroreductase
F6W81_RS16215	COG0616	signal peptide processing
F6W81_RS16220	COG0252	asparaginase activity
F6W81_RS16225	COG1335	isochorismatase
F6W81_RS16230	COG2814	Major facilitator Superfamily
F6W81_RS16235	COG1349	DNA-binding transcription factor activity
F6W81_RS16240	COG0667	Aldo Keto reductase
F6W81_RS16245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6W81_RS16250	COG0191	fructose-bisphosphate aldolase activity
F6W81_RS16255	COG1063	alcohol dehydrogenase
F6W81_RS16260	COG2271	Major facilitator Superfamily
F6W81_RS16265	COG1063	alcohol dehydrogenase
F6W81_RS16280	COG3139	Protein of unknown function (DUF1315)
F6W81_RS16305	COG3713	MltA-interacting MipA family protein
F6W81_RS16310	COG2766	serine protein kinase
F6W81_RS16325	COG0386	Belongs to the glutathione peroxidase family
F6W81_RS16345	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS16350	COG0583	DNA-binding transcription factor activity
F6W81_RS16355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F6W81_RS16360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F6W81_RS16370	COG3344	reverse transcriptase
F6W81_RS16385	COG0859	PFAM glycosyl transferase family 9
F6W81_RS16390	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F6W81_RS16400	COG2207	Transcriptional regulator
F6W81_RS16405	COG2807	transmembrane transport
F6W81_RS16410	COG0504	CTP synthase activity
F6W81_RS16415	COG1683	Conserved Protein
F6W81_RS16420	COG3189	MarR family transcriptional regulator
F6W81_RS16425	COG3042	response to heat
F6W81_RS16430	COG2203	Gaf domain
F6W81_RS16430	COG2199	diguanylate cyclase activity
F6W81_RS16450	COG3182	Iron-regulated membrane protein
F6W81_RS16460	COG1560	Kdo2-lipid A biosynthetic process
F6W81_RS16470	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
F6W81_RS16475	COG3706	GGDEF domain
F6W81_RS16480	COG0583	DNA-binding transcription factor activity
F6W81_RS16485	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F6W81_RS16510	COG1294	oxidase, subunit
F6W81_RS16515	COG1271	oxidase subunit
F6W81_RS16520	COG3546	catalase activity
F6W81_RS16525	COG3685	Protein conserved in bacteria
F6W81_RS16530	COG3685	Protein conserved in bacteria
F6W81_RS16535	COG3729	General stress protein
F6W81_RS16540	COG1063	alcohol dehydrogenase
F6W81_RS16545	COG3813	Protein conserved in bacteria
F6W81_RS16560	COG0640	Transcriptional regulator
F6W81_RS16565	COG0538	isocitrate dehydrogenase activity
F6W81_RS16655	COG0616	signal peptide processing
F6W81_RS16670	COG4626	Terminase
F6W81_RS16670	COG1802	Transcriptional regulator
F6W81_RS16710	COG3772	lysozyme
F6W81_RS16735	COG1403	HNH endonuclease
F6W81_RS16760	COG3344	reverse transcriptase
F6W81_RS16770	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F6W81_RS16815	COG1396	sequence-specific DNA binding
F6W81_RS16840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F6W81_RS16850	COG0582	viral genome integration into host DNA
F6W81_RS16855	COG0538	isocitrate dehydrogenase activity
F6W81_RS16985	COG4695	Portal protein
F6W81_RS16995	COG1802	Transcriptional regulator
F6W81_RS16995	COG4626	Terminase
F6W81_RS17035	COG3179	chitinase
F6W81_RS17060	COG1403	HNH endonuclease
F6W81_RS17065	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
F6W81_RS17145	COG0582	viral genome integration into host DNA
F6W81_RS17150	COG0538	isocitrate dehydrogenase activity
F6W81_RS17155	COG1187	pseudouridine synthase activity
F6W81_RS17175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F6W81_RS17195	COG2205	protein histidine kinase activity
F6W81_RS17200	COG2850	peptidyl-arginine hydroxylation
F6W81_RS17220	COG1177	transmembrane transport
F6W81_RS17235	COG0318	PFAM AMP-dependent synthetase and ligase
F6W81_RS17245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F6W81_RS17255	COG4591	ABC-type transport system involved in lipoprotein release permease component
F6W81_RS17265	COG4591	ABC-type transport system involved in lipoprotein release permease component
F6W81_RS17270	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F6W81_RS17275	COG1388	LysM domain
F6W81_RS17275	COG1376	ErfK ybiS ycfS ynhG family protein
F6W81_RS17285	COG1309	transcriptional regulator
F6W81_RS17295	COG3134	Outer membrane lipoprotein
F6W81_RS17300	COG1252	NADH dehydrogenase
F6W81_RS17325	COG5633	Lipoprotein
F6W81_RS17330	COG0537	adenosine 5'-monophosphoramidase activity
F6W81_RS17340	COG0084	hydrolase, TatD family'
F6W81_RS17345	COG0470	DNA polymerase III
F6W81_RS17355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F6W81_RS17360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F6W81_RS17365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F6W81_RS17380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F6W81_RS17400	COG1399	metal-binding, possibly nucleic acid-binding protein
F6W81_RS17415	COG1530	ribonuclease E activity
F6W81_RS17420	COG0583	DNA-binding transcription factor activity
F6W81_RS17425	COG2814	Major facilitator Superfamily
F6W81_RS17445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F6W81_RS17495	COG1560	Kdo2-lipid A biosynthetic process
F6W81_RS17510	COG5645	(Lipo)protein
F6W81_RS17545	COG3381	protein complex oligomerization
F6W81_RS17585	COG0583	DNA-binding transcription factor activity
F6W81_RS17595	COG1335	isochorismatase
F6W81_RS17605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F6W81_RS17610	COG1702	phosphate starvation-inducible protein PhoH
F6W81_RS17630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F6W81_RS17640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F6W81_RS17655	COG1309	transcriptional regulator
F6W81_RS17690	COG2233	PERMEase
F6W81_RS17700	COG3729	General stress protein
F6W81_RS17725	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS17740	COG0531	amino acid
F6W81_RS17750	COG0174	glutamine synthetase
F6W81_RS17755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F6W81_RS17760	COG1917	Cupin 2, conserved barrel domain protein
F6W81_RS17760	COG1396	sequence-specific DNA binding
F6W81_RS17765	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS17770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F6W81_RS17775	COG0583	DNA-binding transcription factor activity
F6W81_RS17780	COG0473	3-isopropylmalate dehydrogenase activity
F6W81_RS17785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F6W81_RS17790	COG4638	Rieske (2fe-2S)
F6W81_RS17795	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS17800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F6W81_RS17810	COG2200	EAL domain
F6W81_RS17815	COG2200	EAL domain
F6W81_RS17830	COG0670	Belongs to the BI1 family
F6W81_RS17845	COG2207	Transcriptional regulator
F6W81_RS17850	COG1881	PFAM PEBP family protein
F6W81_RS17865	COG1832	CoA-binding protein
F6W81_RS17875	COG0210	DNA helicase
F6W81_RS17880	COG3304	Inner membrane component domain
F6W81_RS17885	COG1289	transmembrane transporter activity
F6W81_RS17890	COG3070	regulator of competence-specific genes
F6W81_RS17915	COG1067	ATP-dependent peptidase activity
F6W81_RS17925	COG3130	regulation of translation
F6W81_RS17930	COG3009	Protein conserved in bacteria
F6W81_RS17935	COG3008	intermembrane lipid transfer
F6W81_RS17935	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F6W81_RS17940	COG2995	paraquat-inducible protein a
F6W81_RS17945	COG0488	(ABC) transporter
F6W81_RS17955	COG0633	Ferredoxin
F6W81_RS17955	COG3217	Mosc domain protein beta barrel domain protein
F6W81_RS17970	COG0431	NADPH-dependent FMN reductase
F6W81_RS17975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F6W81_RS17980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F6W81_RS17985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F6W81_RS17995	COG0308	aminopeptidase N
F6W81_RS18005	COG1473	amidohydrolase
F6W81_RS18015	COG0814	amino acid
F6W81_RS18025	COG1522	sequence-specific DNA binding
F6W81_RS18040	COG1448	Aminotransferase
F6W81_RS18045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F6W81_RS18050	COG3108	Peptidase M15
F6W81_RS18055	COG2989	Protein conserved in bacteria
F6W81_RS18065	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
F6W81_RS18075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F6W81_RS18080	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F6W81_RS18085	COG3173	Aminoglycoside phosphotransferase
F6W81_RS18100	COG3214	Protein conserved in bacteria
F6W81_RS18115	COG0658	competence protein
F6W81_RS18115	COG2333	competence protein COMEC
F6W81_RS18125	COG0539	negative regulation of cytoplasmic translation
F6W81_RS18145	COG2323	membrane
F6W81_RS18150	COG1944	ATP diphosphatase activity
F6W81_RS18155	COG2116	formate transmembrane transporter activity
F6W81_RS18160	COG1882	Formate acetyltransferase
F6W81_RS18165	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F6W81_RS18170	COG0477	Major facilitator Superfamily
F6W81_RS18180	COG3302	dmso reductase anchor subunit
F6W81_RS18185	COG0437	4 iron, 4 sulfur cluster binding
F6W81_RS18190	COG0243	molybdopterin cofactor binding
F6W81_RS18200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F6W81_RS18210	COG1178	ABC-type Fe3 transport system permease component
F6W81_RS18210	COG1674	ftsk spoiiie
F6W81_RS18220	COG0492	ferredoxin-NADP+ reductase activity
F6W81_RS18225	COG4988	ABC transporter
F6W81_RS18230	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F6W81_RS18245	COG0542	response to heat
F6W81_RS18255	COG1278	Cold shock
F6W81_RS18265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6W81_RS18270	COG3593	DNA synthesis involved in DNA repair
F6W81_RS18280	COG2431	L-lysine efflux transmembrane transporter activity
F6W81_RS18290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F6W81_RS18300	COG0028	Belongs to the TPP enzyme family
F6W81_RS18305	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
F6W81_RS18310	COG0702	epimerase
F6W81_RS18315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F6W81_RS18320	COG3023	N-Acetylmuramoyl-L-alanine amidase
F6W81_RS18325	COG2203	Gaf domain
F6W81_RS18325	COG4251	negative regulation of phosphorylation
F6W81_RS18325	COG3706	GGDEF domain
F6W81_RS18325	COG5001	Diguanylate cyclase
F6W81_RS18335	COG1126	abc transporter atp-binding protein
F6W81_RS18340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6W81_RS18345	COG4215	(ABC) transporter
F6W81_RS18350	COG4160	amino acid transport
F6W81_RS18355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6W81_RS18360	COG5002	protein histidine kinase activity
F6W81_RS18365	COG0745	RESPONSE REGULATOR receiver
F6W81_RS18380	COG1177	transmembrane transport
F6W81_RS18385	COG1176	ABC-type spermidine putrescine transport system, permease component I
F6W81_RS18390	COG3842	ATPase activity
F6W81_RS18395	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F6W81_RS18580	COG4695	Portal protein
F6W81_RS18615	COG3344	reverse transcriptase
F6W81_RS18625	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F6W81_RS18630	COG3226	Transcriptional regulator
F6W81_RS18635	COG0738	Major facilitator superfamily
F6W81_RS18640	COG0561	phosphatase activity
F6W81_RS18645	COG2814	Major facilitator Superfamily
F6W81_RS18655	COG0671	phosphoesterase, PA-phosphatase related
F6W81_RS18660	COG1349	DNA-binding transcription factor activity
F6W81_RS18665	COG1686	Belongs to the peptidase S11 family
F6W81_RS18670	COG0625	glutathione transferase activity
F6W81_RS18675	COG2133	pyrroloquinoline quinone binding
F6W81_RS18685	COG2223	nitrite transmembrane transporter activity
F6W81_RS18705	COG0747	negative chemotaxis
F6W81_RS18720	COG0303	'Molybdopterin
F6W81_RS18725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F6W81_RS18730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F6W81_RS18735	COG1882	Formate acetyltransferase
F6W81_RS18740	COG0561	phosphatase activity
F6W81_RS18750	COG1609	Transcriptional regulator
F6W81_RS18755	COG2271	Major facilitator Superfamily
F6W81_RS18765	COG0488	(ABC) transporter
F6W81_RS18770	COG2365	Tyrosine phosphatase family
F6W81_RS18775	COG1376	ErfK ybiS ycfS ynhG family protein
F6W81_RS18780	COG2188	Transcriptional regulator
F6W81_RS18785	COG2723	6-phospho-beta-galactosidase activity
F6W81_RS18790	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F6W81_RS18795	COG1321	iron dependent repressor
F6W81_RS18805	COG2194	sulfuric ester hydrolase activity
F6W81_RS18810	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F6W81_RS18825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6W81_RS18830	COG0765	amino acid transport
F6W81_RS18835	COG1126	abc transporter atp-binding protein
F6W81_RS18840	COG0668	transmembrane transport
F6W81_RS18850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F6W81_RS18860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F6W81_RS18870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F6W81_RS18875	COG1199	ATP-dependent helicase activity
F6W81_RS18880	COG0513	Belongs to the DEAD box helicase family
F6W81_RS18885	COG3958	Transketolase
F6W81_RS18890	COG3959	Transketolase, thiamine diphosphate binding domain
F6W81_RS18895	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS18900	COG2271	Major facilitator Superfamily
F6W81_RS18905	COG0583	DNA-binding transcription factor activity
F6W81_RS18910	COG1309	transcriptional regulator
F6W81_RS18915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6W81_RS18920	COG1131	(ABC) transporter
F6W81_RS18925	COG0842	Transport permease protein
F6W81_RS18930	COG0842	Transport permease protein
F6W81_RS18940	COG3568	Endonuclease Exonuclease Phosphatase
F6W81_RS18945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F6W81_RS18950	COG0392	lysyltransferase activity
F6W81_RS18960	COG0670	Belongs to the BI1 family
F6W81_RS18965	COG0314	molybdopterin synthase activity
F6W81_RS18970	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F6W81_RS18980	COG0521	Mo-molybdopterin cofactor biosynthetic process
F6W81_RS19005	COG0745	RESPONSE REGULATOR receiver
F6W81_RS19010	COG0642	Histidine kinase
F6W81_RS19040	COG2226	methyltransferase
F6W81_RS19055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F6W81_RS19060	COG1881	PFAM PEBP family protein
F6W81_RS19095	COG4677	pectinesterase activity
F6W81_RS19125	COG0789	Transcriptional regulator
F6W81_RS19130	COG2200	EAL domain
F6W81_RS19155	COG0561	phosphatase activity
F6W81_RS19160	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F6W81_RS19165	COG4149	molybdate abc transporter
F6W81_RS19170	COG0725	ABC transporter, periplasmic molybdate-binding protein
F6W81_RS19180	COG3585	molybdate ion transport
F6W81_RS19180	COG2005	Transcriptional regulator
F6W81_RS19185	COG1119	ATPase activity
F6W81_RS19195	COG1085	galactose-1-phosphate uridylyltransferase
F6W81_RS19205	COG2017	converts alpha-aldose to the beta-anomer
F6W81_RS19215	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F6W81_RS19230	COG3201	nicotinamide mononucleotide transporter
F6W81_RS19235	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F6W81_RS19275	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
F6W81_RS19280	COG2885	chlorophyll binding
F6W81_RS19290	COG3064	Membrane
F6W81_RS19295	COG0848	biopolymer transport protein
F6W81_RS19300	COG0811	peptide transport
F6W81_RS19305	COG0824	Thioesterase
F6W81_RS19310	COG3790	cyd operon protein YbgE
F6W81_RS19315	COG4890	Cyd operon protein YbgT
F6W81_RS19320	COG1294	oxidase, subunit
F6W81_RS19325	COG1271	oxidase subunit
F6W81_RS19335	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F6W81_RS19345	COG0508	dehydrogenase complex catalyzes the overall conversion of
F6W81_RS19350	COG0567	Dehydrogenase, E1 component
F6W81_RS19355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F6W81_RS19360	COG1053	succinate dehydrogenase
F6W81_RS19365	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F6W81_RS19370	COG2009	succinate dehydrogenase
F6W81_RS19405	COG1984	allophanate hydrolase subunit 2
F6W81_RS19410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F6W81_RS19425	COG0415	Belongs to the DNA photolyase family
F6W81_RS19455	COG2205	protein histidine kinase activity
F6W81_RS19460	COG0745	RESPONSE REGULATOR receiver
F6W81_RS19470	COG0033	Phosphoglucomutase
F6W81_RS19480	COG0596	Alpha beta hydrolase
F6W81_RS19495	COG0735	belongs to the Fur family
F6W81_RS19535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F6W81_RS19540	COG1940	carbohydrate kinase activity
F6W81_RS19540	COG1846	Transcriptional regulator
F6W81_RS19545	COG0647	UMP catabolic process
F6W81_RS19550	COG0367	asparagine synthase
F6W81_RS19595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F6W81_RS19605	COG1702	phosphate starvation-inducible protein PhoH
F6W81_RS19615	COG4535	Mg2 and Co2 transporter CorC
F6W81_RS19630	COG0765	amino acid transport
F6W81_RS19635	COG0765	amino acid transport
F6W81_RS19640	COG1126	abc transporter atp-binding protein
F6W81_RS19655	COG2888	peptidyl-tyrosine sulfation
F6W81_RS19670	COG1466	dna polymerase III delta subunit
F6W81_RS19685	COG0799	negative regulation of ribosome biogenesis
F6W81_RS19695	COG0768	penicillin binding
F6W81_RS19700	COG0772	Belongs to the SEDS family
F6W81_RS19705	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F6W81_RS19710	COG1686	Belongs to the peptidase S11 family
F6W81_RS19725	COG0583	DNA-binding transcription factor activity
F6W81_RS19740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F6W81_RS19760	COG3069	C4-dicarboxylate transmembrane transporter activity
F6W81_RS19765	COG3719	Belongs to the RNase T2 family
F6W81_RS19770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F6W81_RS19790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F6W81_RS19795	COG0583	DNA-binding transcription factor activity
F6W81_RS19800	COG3969	phosphoadenosine phosphosulfate
F6W81_RS19805	COG1475	DNA binding
F6W81_RS19810	COG0436	Aminotransferase
F6W81_RS19835	COG1129	ABC transporter
F6W81_RS19840	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS19845	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS19855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F6W81_RS19870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F6W81_RS19880	COG0402	S-adenosylhomocysteine deaminase activity
F6W81_RS19890	COG0483	inositol monophosphate 1-phosphatase activity
F6W81_RS19895	COG2271	Major facilitator Superfamily
F6W81_RS19925	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS19930	COG1129	ABC transporter
F6W81_RS19935	COG0371	Dehydrogenase
F6W81_RS19940	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS19955	COG2879	small protein
F6W81_RS19960	COG1966	Carbon starvation protein
F6W81_RS19970	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS19975	COG1535	isochorismatase
F6W81_RS19975	COG3433	isochorismatase activity
F6W81_RS19980	COG1021	2,3-dihydroxybenzoate-AMP ligase
F6W81_RS19985	COG1169	isochorismate synthase
F6W81_RS19990	COG4592	Periplasmic binding protein
F6W81_RS20000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6W81_RS20005	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6W81_RS20010	COG1120	ATPase activity
F6W81_RS20015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F6W81_RS20015	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F6W81_RS20020	COG3251	PFAM MbtH domain protein
F6W81_RS20025	COG2382	esterase
F6W81_RS20030	COG4771	TonB-dependent receptor
F6W81_RS20035	COG2977	Belongs to the P-Pant transferase superfamily
F6W81_RS20040	COG3958	Transketolase
F6W81_RS20045	COG3959	Transketolase, thiamine diphosphate binding domain
F6W81_RS20050	COG2390	Transcriptional regulator
F6W81_RS20055	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F6W81_RS20060	COG1879	ABC-type sugar transport system periplasmic component
F6W81_RS20070	COG1129	ABC transporter
F6W81_RS20075	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS20085	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS20095	COG0583	DNA-binding transcription factor activity
F6W81_RS20100	COG0668	transmembrane transport
F6W81_RS20110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F6W81_RS20135	COG0747	negative chemotaxis
F6W81_RS20140	COG0601	transmembrane transport
F6W81_RS20145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F6W81_RS20150	COG0444	Belongs to the ABC transporter superfamily
F6W81_RS20155	COG4608	Belongs to the ABC transporter superfamily
F6W81_RS20160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F6W81_RS20165	COG4221	oxidoreductase activity
F6W81_RS20175	COG4215	(ABC) transporter
F6W81_RS20180	COG0765	amino acid transport
F6W81_RS20185	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
F6W81_RS20200	COG0697	spore germination
F6W81_RS20210	COG3698	Phosphodiester glycosidase
F6W81_RS20260	COG2315	Protein conserved in bacteria
F6W81_RS20265	COG0778	Nitroreductase
F6W81_RS20275	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6W81_RS20285	COG3716	PTS system mannose fructose sorbose family IID component
F6W81_RS20290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F6W81_RS20295	COG2222	sugar isomerase
F6W81_RS20300	COG3933	PFAM sigma-54 factor interaction domain-containing protein
F6W81_RS20300	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F6W81_RS20315	COG0477	Major facilitator Superfamily
F6W81_RS20320	COG0668	transmembrane transport
F6W81_RS20350	COG3188	usher protein
F6W81_RS20365	COG2771	luxR family
F6W81_RS20375	COG0673	inositol 2-dehydrogenase activity
F6W81_RS20385	COG2211	Major facilitator Superfamily
F6W81_RS20390	COG1113	amino acid transport
F6W81_RS20405	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS20410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F6W81_RS20420	COG0531	amino acid
F6W81_RS20465	COG0667	Aldo Keto reductase
F6W81_RS20470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6W81_RS20475	COG1473	amidohydrolase
F6W81_RS20495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6W81_RS20500	COG1120	ATPase activity
F6W81_RS20505	COG1566	PFAM secretion protein HlyD family protein
F6W81_RS20550	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS20555	COG1129	ABC transporter
F6W81_RS20570	COG0673	inositol 2-dehydrogenase activity
F6W81_RS20600	COG3104	oligopeptide transport
F6W81_RS20605	COG1982	Orn Lys Arg decarboxylase major
F6W81_RS20610	COG0531	amino acid
F6W81_RS20615	COG3710	Transcriptional regulator
F6W81_RS20625	COG1560	Kdo2-lipid A biosynthetic process
F6W81_RS20640	COG3188	usher protein
F6W81_RS20645	COG3121	Chaperone
F6W81_RS20650	COG3539	Fimbrial protein
F6W81_RS20705	COG2501	S4 domain
F6W81_RS20715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F6W81_RS20730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F6W81_RS20735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F6W81_RS20750	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F6W81_RS20755	COG4181	ATPase activity
F6W81_RS20760	COG2755	lipolytic protein G-D-S-L family
F6W81_RS20765	COG0300	oxidoreductase activity
F6W81_RS20770	COG3118	belongs to the thioredoxin family
F6W81_RS20780	COG0390	transport system, permease component
F6W81_RS20785	COG4619	ABC transporter
F6W81_RS20790	COG0330	HflC and HflK could
F6W81_RS20795	COG1585	Membrane protein implicated in regulation of membrane protease activity
F6W81_RS20810	COG3735	TraB family
F6W81_RS20815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F6W81_RS20825	COG2223	nitrite transmembrane transporter activity
F6W81_RS20830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F6W81_RS20830	COG4651	solute:proton antiporter activity
F6W81_RS20835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6W81_RS20875	COG2832	Protein of unknown function (DUF454)
F6W81_RS20880	COG3923	Primosomal replication protein n
F6W81_RS20890	COG5464	transposase or invertase
F6W81_RS20895	COG1196	nuclear chromosome segregation
F6W81_RS20895	COG3264	Mechanosensitive ion channel
F6W81_RS20915	COG1309	transcriptional regulator
F6W81_RS20920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6W81_RS20925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6W81_RS20940	COG0110	maltose O-acetyltransferase activity
F6W81_RS20985	COG1874	Beta-galactosidase
F6W81_RS20990	COG3867	Arabinogalactan endo-beta-1,4-galactanase
F6W81_RS20995	COG3833	ABC-type maltose transport systems, permease component
F6W81_RS21000	COG1175	transmembrane transport
F6W81_RS21005	COG2182	Extracellular solute-binding protein
F6W81_RS21015	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F6W81_RS21030	COG2364	Membrane
F6W81_RS21060	COG3695	enzyme binding
F6W81_RS21065	COG3126	Type III secretion system lipoprotein chaperone (YscW)
F6W81_RS21070	COG1946	Acyl-CoA thioesterase
F6W81_RS21075	COG0004	ammonium transporteR
F6W81_RS21080	COG0347	Belongs to the P(II) protein family
F6W81_RS21085	COG1132	(ABC) transporter
F6W81_RS21090	COG1132	(ABC) transporter
F6W81_RS21095	COG1522	sequence-specific DNA binding
F6W81_RS21110	COG4533	DNA binding
F6W81_RS21120	COG0824	Thioesterase
F6W81_RS21125	COG1555	photosystem II stabilization
F6W81_RS21130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F6W81_RS21135	COG0776	regulation of translation
F6W81_RS21140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F6W81_RS21170	COG0271	Belongs to the BolA IbaG family
F6W81_RS21175	COG3056	Lipoprotein
F6W81_RS21180	COG2223	nitrite transmembrane transporter activity
F6W81_RS21185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F6W81_RS21190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F6W81_RS21195	COG1845	cytochrome c oxidase, subunit III
F6W81_RS21200	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F6W81_RS21215	COG1414	Transcriptional regulator
F6W81_RS21220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F6W81_RS21225	COG1053	succinate dehydrogenase
F6W81_RS21235	COG1053	succinate dehydrogenase
F6W81_RS21250	COG0673	inositol 2-dehydrogenase activity
F6W81_RS21255	COG2814	Major facilitator Superfamily
F6W81_RS21265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F6W81_RS21270	COG0693	protein deglycase activity
F6W81_RS21290	COG0142	geranyltranstransferase activity
F6W81_RS21300	COG0667	Aldo Keto reductase
F6W81_RS21305	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F6W81_RS21325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F6W81_RS21325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F6W81_RS21335	COG4238	major outer membrane lipoprotein
F6W81_RS21355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F6W81_RS21360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F6W81_RS21365	COG1862	Preprotein translocase
F6W81_RS21385	COG0450	alkyl hydroperoxide reductase
F6W81_RS21390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS21405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6W81_RS21415	COG1228	amidohydrolase
F6W81_RS21425	COG1335	isochorismatase
F6W81_RS21430	COG0583	DNA-binding transcription factor activity
F6W81_RS21435	COG0366	Alpha amylase catalytic
F6W81_RS21460	COG0420	3'-5' exonuclease activity
F6W81_RS21465	COG0419	ATPase involved in DNA repair
F6W81_RS21470	COG1940	carbohydrate kinase activity
F6W81_RS21485	COG4126	flavin adenine dinucleotide binding
F6W81_RS21495	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F6W81_RS21500	COG3416	Protein conserved in bacteria
F6W81_RS21510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F6W81_RS21520	COG1785	Belongs to the alkaline phosphatase family
F6W81_RS21560	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F6W81_RS21565	COG1335	isochorismatase
F6W81_RS21570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F6W81_RS21575	COG0113	porphobilinogen synthase activity
F6W81_RS21585	COG2175	clavaminate synthase activity
F6W81_RS21590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F6W81_RS21595	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F6W81_RS21600	COG4521	taurine ABC transporter
F6W81_RS21605	COG2040	homocysteine
F6W81_RS21610	COG0833	amino acid
F6W81_RS21620	COG4303	Ethanolamine ammonia lyase large subunit
F6W81_RS21625	COG4302	ethanolamine ammonia-lyase activity
F6W81_RS21660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6W81_RS21665	COG1126	abc transporter atp-binding protein
F6W81_RS21670	COG0765	amino acid transport
F6W81_RS21675	COG0765	amino acid transport
F6W81_RS21690	COG3188	usher protein
F6W81_RS21715	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
F6W81_RS21725	COG3639	organic phosphonate transmembrane transporter activity
F6W81_RS21750	COG0791	NLP P60 protein
F6W81_RS21775	COG0582	viral genome integration into host DNA
F6W81_RS21780	COG1192	Involved in chromosome partitioning
F6W81_RS21840	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F6W81_RS21845	COG0022	dehydrogenase e1 component
F6W81_RS21850	COG0508	dehydrogenase complex catalyzes the overall conversion of
F6W81_RS21855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F6W81_RS21880	COG1070	Carbohydrate kinase
F6W81_RS21885	COG1028	Short-chain dehydrogenase reductase Sdr
F6W81_RS21890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F6W81_RS21895	COG3775	system Galactitol-specific IIC component
F6W81_RS21900	COG0625	glutathione transferase activity
F6W81_RS21905	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
F6W81_RS21920	COG0579	oxidoreductase
F6W81_RS21925	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS21930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F6W81_RS21935	COG1113	amino acid transport
F6W81_RS21940	COG1802	Transcriptional regulator
F6W81_RS21960	COG2195	Cleaves the N-terminal amino acid of tripeptides
F6W81_RS21965	COG0454	-acetyltransferase
F6W81_RS21980	COG2991	Protein conserved in bacteria
F6W81_RS21995	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F6W81_RS22000	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F6W81_RS22015	COG3034	peptidoglycan biosynthetic process
F6W81_RS22020	COG0121	glutamine amidotransferase
F6W81_RS22030	COG1960	acyl-CoA dehydrogenase activity
F6W81_RS22035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F6W81_RS22045	COG0583	DNA-binding transcription factor activity
F6W81_RS22055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F6W81_RS22065	COG2226	methyltransferase
F6W81_RS22075	COG0741	lytic transglycosylase activity
F6W81_RS22075	COG1388	LysM domain
F6W81_RS22080	COG2226	methyltransferase
F6W81_RS22090	COG2814	Major facilitator Superfamily
F6W81_RS22095	COG0583	DNA-binding transcription factor activity
F6W81_RS22100	COG0656	L-ascorbic acid biosynthetic process
F6W81_RS22135	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F6W81_RS22145	COG2011	ABC-type metal ion transport system permease component
F6W81_RS22150	COG1464	Belongs to the NlpA lipoprotein family
F6W81_RS22160	COG1720	tRNA m6t6A37 methyltransferase activity
F6W81_RS22170	COG0791	NLP P60 protein
F6W81_RS22175	COG3015	lipoprotein NlpE involved in copper resistance
F6W81_RS22180	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F6W81_RS22195	COG4568	rho-dependent transcription termination
F6W81_RS22205	COG0346	lactoylglutathione lyase activity
F6W81_RS22210	COG1982	Orn Lys Arg decarboxylase major
F6W81_RS22250	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
F6W81_RS22260	COG0750	zinc metalloprotease
F6W81_RS22265	COG0575	Belongs to the CDS family
F6W81_RS22280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F6W81_RS22305	COG0024	Methionine aminopeptidase
F6W81_RS22310	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F6W81_RS22325	COG3835	regulator
F6W81_RS22330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F6W81_RS22350	COG2860	membrane
F6W81_RS22370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F6W81_RS22375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F6W81_RS22380	COG1120	ATPase activity
F6W81_RS22390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F6W81_RS22475	COG1643	Atp-dependent helicase
F6W81_RS22480	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F6W81_RS22500	COG0617	tRNA 3'-terminal CCA addition
F6W81_RS22505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F6W81_RS22525	COG0726	polysaccharide deacetylase
F6W81_RS22530	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS22535	COG0842	Transport permease protein
F6W81_RS22540	COG1131	(ABC) transporter
F6W81_RS22545	COG0288	reversible hydration of carbon dioxide
F6W81_RS22555	COG4993	Dehydrogenase
F6W81_RS22560	COG2132	Multicopper oxidase
F6W81_RS22615	COG3064	Membrane
F6W81_RS22630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F6W81_RS22635	COG0508	dehydrogenase complex catalyzes the overall conversion of
F6W81_RS22640	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F6W81_RS22645	COG2186	Transcriptional regulator
F6W81_RS22650	COG1113	amino acid transport
F6W81_RS22655	COG2211	Major facilitator Superfamily
F6W81_RS22660	COG3940	Belongs to the glycosyl hydrolase 43 family
F6W81_RS22665	COG3725	Membrane protein required for beta-lactamase induction
F6W81_RS22670	COG3023	N-Acetylmuramoyl-L-alanine amidase
F6W81_RS22680	COG4969	Belongs to the N-Me-Phe pilin family
F6W81_RS22685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F6W81_RS22690	COG1459	type II secretion system
F6W81_RS22715	COG0494	nUDIX hydrolase
F6W81_RS22735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F6W81_RS22740	COG0849	cell division
F6W81_RS22765	COG0772	Belongs to the SEDS family
F6W81_RS22780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F6W81_RS22785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F6W81_RS22790	COG0768	penicillin binding
F6W81_RS22810	COG1609	Transcriptional regulator
F6W81_RS22820	COG0028	Belongs to the TPP enzyme family
F6W81_RS22870	COG0738	Major facilitator superfamily
F6W81_RS22880	COG0583	DNA-binding transcription factor activity
F6W81_RS22885	COG2271	Major facilitator Superfamily
F6W81_RS22890	COG2814	Major facilitator Superfamily
F6W81_RS22910	COG1178	ABC-type Fe3 transport system permease component
F6W81_RS22920	COG0586	Pfam SNARE associated Golgi protein
F6W81_RS22940	COG0235	Class ii aldolase
F6W81_RS22945	COG0417	DNA replication proofreading
F6W81_RS22955	COG0564	pseudouridine synthase activity
F6W81_RS22965	COG3493	citrate carrier protein
F6W81_RS22980	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F6W81_RS22985	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F6W81_RS22995	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F6W81_RS23040	COG0505	Belongs to the CarA family
F6W81_RS23105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F6W81_RS23130	COG1047	Peptidyl-prolyl cis-trans
F6W81_RS23145	COG0196	riboflavin kinase activity
F6W81_RS23160	COG0583	DNA-binding transcription factor activity
F6W81_RS23185	COG4735	regulation of single-species biofilm formation
F6W81_RS23190	COG1584	GPR1 FUN34 yaaH family protein
F6W81_RS23195	COG0477	Major facilitator Superfamily
F6W81_RS23200	COG0521	Mo-molybdopterin cofactor biosynthetic process
F6W81_RS23205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F6W81_RS23210	COG1115	amino acid carrier protein
F6W81_RS23225	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F6W81_RS23235	COG0460	homoserine dehydrogenase
F6W81_RS23235	COG0527	aspartate kinase activity
F6W81_RS23245	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F6W81_RS23255	COG0745	RESPONSE REGULATOR receiver
F6W81_RS23260	COG4452	Inner membrane protein CreD
F6W81_RS23265	COG2205	protein histidine kinase activity
F6W81_RS23270	COG0745	RESPONSE REGULATOR receiver
F6W81_RS23275	COG3045	CreA protein
F6W81_RS23280	COG2207	Transcriptional regulator
F6W81_RS23280	COG3708	Transcriptional regulator
F6W81_RS23300	COG0741	lytic transglycosylase activity
F6W81_RS23305	COG0488	(ABC) transporter
F6W81_RS23315	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
F6W81_RS23320	COG0560	Phosphoserine phosphatase
F6W81_RS23325	COG3726	membrane protein affecting hemolysin expression
F6W81_RS23355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F6W81_RS23360	COG0084	hydrolase, TatD family'
F6W81_RS23365	COG4667	esterase of the alpha-beta hydrolase superfamily
F6W81_RS23375	COG2823	Periplasmic or secreted lipoprotein
F6W81_RS23385	COG1011	Hydrolase
F6W81_RS23390	COG0456	acetyltransferase
F6W81_RS23395	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
F6W81_RS23425	COG3706	GGDEF domain
F6W81_RS23430	COG4114	ferric iron reductase
F6W81_RS23440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F6W81_RS23445	COG2197	response regulator
F6W81_RS23450	COG2197	response regulator
F6W81_RS23465	COG2966	Psort location CytoplasmicMembrane, score
F6W81_RS23480	COG1484	DNA-dependent DNA replication
F6W81_RS23495	COG5464	transposase or invertase
F6W81_RS23505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F6W81_RS23510	COG3716	PTS system mannose fructose sorbose family IID component
F6W81_RS23515	COG3715	PTS system
F6W81_RS23530	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F6W81_RS23530	COG3933	PFAM sigma-54 factor interaction domain-containing protein
F6W81_RS23540	COG1063	alcohol dehydrogenase
F6W81_RS23545	COG1802	Transcriptional regulator
F6W81_RS23550	COG2271	Major facilitator Superfamily
F6W81_RS23555	COG0456	acetyltransferase
F6W81_RS23555	COG1214	PFAM Peptidase M22, glycoprotease
F6W81_RS23565	COG1737	Transcriptional regulator
F6W81_RS23570	COG0800	Aldolase
F6W81_RS23575	COG3734	2-keto-3-deoxy-galactonokinase
F6W81_RS23590	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F6W81_RS23620	COG1846	Transcriptional regulator
F6W81_RS23630	COG0179	Fumarylacetoacetate (FAA) hydrolase
F6W81_RS23640	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS23645	COG3384	dioxygenase
F6W81_RS23655	COG3971	2-oxopent-4-enoate hydratase activity
F6W81_RS23675	COG2368	4-hydroxyphenylacetate
F6W81_RS23680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F6W81_RS23695	COG1966	Carbon starvation protein
F6W81_RS23700	COG2879	small protein
F6W81_RS23705	COG0523	cobalamin synthesis protein
F6W81_RS23715	COG1012	belongs to the aldehyde dehydrogenase family
F6W81_RS23720	COG5464	transposase or invertase
F6W81_RS23725	COG1917	Cupin 2, conserved barrel domain protein
F6W81_RS23725	COG2207	Transcriptional regulator
F6W81_RS23735	COG2733	membrane
F6W81_RS23750	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
F6W81_RS23755	COG1924	4 iron, 4 sulfur cluster binding
F6W81_RS23770	COG1566	PFAM secretion protein HlyD family protein
F6W81_RS23780	COG5457	Domain of unknown function (DUF1127)
F6W81_RS23785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F6W81_RS23795	COG0583	DNA-binding transcription factor activity
F6W81_RS23800	COG2249	NAD(P)H dehydrogenase (quinone) activity
F6W81_RS23810	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS23815	COG1129	ABC transporter
F6W81_RS23820	COG1879	ABC-type sugar transport system periplasmic component
F6W81_RS23830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6W81_RS23835	COG1129	ABC transporter
F6W81_RS23835	COG0842	Transport permease protein
F6W81_RS23840	COG0842	Transport permease protein
F6W81_RS23870	COG2850	peptidyl-arginine hydroxylation
F6W81_RS23885	COG5002	protein histidine kinase activity
F6W81_RS23890	COG0745	RESPONSE REGULATOR receiver
F6W81_RS23895	COG1538	Outer membrane efflux protein
F6W81_RS23900	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6W81_RS23905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F6W81_RS23910	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F6W81_RS23920	COG3040	lipid binding
F6W81_RS23925	COG0789	Transcriptional regulator
F6W81_RS23935	COG0300	oxidoreductase activity
F6W81_RS23950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F6W81_RS23970	COG3272	Protein of unknown function (DUF1722)
F6W81_RS23975	COG4580	involved in the transport of maltose and maltodextrins
F6W81_RS23985	COG2211	Major facilitator Superfamily
F6W81_RS23990	COG3507	Belongs to the glycosyl hydrolase 43 family
F6W81_RS24105	COG3039	Transposase
F6W81_RS24115	COG0582	viral genome integration into host DNA
F6W81_RS24125	COG0288	reversible hydration of carbon dioxide
F6W81_RS24130	COG0659	secondary active sulfate transmembrane transporter activity
F6W81_RS24135	COG1064	alcohol dehydrogenase
F6W81_RS24140	COG1175	transmembrane transport
F6W81_RS24145	COG0395	ABC-type sugar transport system, permease component
F6W81_RS24150	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F6W81_RS24155	COG3842	ATPase activity
F6W81_RS24160	COG1653	transport
F6W81_RS24170	COG1082	Xylose isomerase domain protein TIM barrel
F6W81_RS24180	COG3962	Belongs to the TPP enzyme family
F6W81_RS24185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6W81_RS24190	COG1737	Transcriptional regulator
F6W81_RS24190	COG0837	glucose binding
F6W81_RS24210	COG3718	enzyme involved in inositol metabolism
F6W81_RS24225	COG0433	COG0433 Predicted ATPase
F6W81_RS24230	COG0795	lipopolysaccharide-transporting ATPase activity
F6W81_RS24235	COG0795	lipopolysaccharide-transporting ATPase activity
F6W81_RS24245	COG2927	DNA polymerase III (CHI subunit)
F6W81_RS24250	COG0525	valine-tRNA ligase activity
F6W81_RS24275	COG2188	Transcriptional regulator
F6W81_RS24280	COG1288	antiporter activity
F6W81_RS24285	COG1228	amidohydrolase
F6W81_RS24290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6W81_RS24295	COG2222	sugar isomerase
F6W81_RS24300	COG2731	YhcH YjgK YiaL family protein
F6W81_RS24340	COG1263	PTS System
F6W81_RS24340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F6W81_RS24345	COG0366	Alpha amylase catalytic
F6W81_RS24350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F6W81_RS24355	COG1486	melibiose metabolic process
F6W81_RS24375	COG0602	queuosine metabolic process
F6W81_RS24380	COG2026	Addiction module toxin, RelE StbE family
F6W81_RS24385	COG3077	Addiction module antitoxin, RelB DinJ family
F6W81_RS24390	COG3711	transcriptional antiterminator
F6W81_RS24390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F6W81_RS24395	COG2706	6-phosphogluconolactonase activity
F6W81_RS24410	COG3964	amidohydrolase
F6W81_RS24445	COG0312	modulator of DNA gyrase
F6W81_RS24465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F6W81_RS24475	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS24480	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS24485	COG1129	ABC transporter
F6W81_RS24490	COG1879	ABC-type sugar transport system periplasmic component
F6W81_RS24510	COG2105	PFAM AIG2 family protein
F6W81_RS24515	COG2911	Protein conserved in bacteria
F6W81_RS24520	COG0729	surface antigen
F6W81_RS24530	COG1253	flavin adenine dinucleotide binding
F6W81_RS24545	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
F6W81_RS24560	COG1733	regulation of RNA biosynthetic process
F6W81_RS24565	COG0702	epimerase
F6W81_RS24575	COG0697	spore germination
F6W81_RS24585	COG1113	amino acid transport
F6W81_RS24590	COG0545	Peptidyl-prolyl cis-trans isomerase
F6W81_RS24595	COG3061	Opacity-associated protein A
F6W81_RS24605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F6W81_RS24610	COG2965	DNA replication, synthesis of RNA primer
F6W81_RS24670	COG1073	alpha beta
F6W81_RS24675	COG3650	response to hydrogen peroxide
F6W81_RS24685	COG1960	acyl-CoA dehydrogenase activity
F6W81_RS24690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F6W81_RS24695	COG0557	exoribonuclease II activity
F6W81_RS24710	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
F6W81_RS24720	COG0330	HflC and HflK could
F6W81_RS24725	COG0330	HflC and HflK could
F6W81_RS24730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F6W81_RS24750	COG0860	N-Acetylmuramoyl-L-alanine amidase
F6W81_RS24755	COG0802	atpase or kinase
F6W81_RS24760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F6W81_RS24760	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F6W81_RS24765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F6W81_RS24785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F6W81_RS24805	COG1511	domain protein
F6W81_RS24805	COG3264	Mechanosensitive ion channel
F6W81_RS24820	COG1053	succinate dehydrogenase
F6W81_RS24825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F6W81_RS24845	COG2076	Multidrug Resistance protein
F6W81_RS24850	COG5510	response to toxic substance
F6W81_RS24865	COG1509	lysine 2,3-aminomutase activity
F6W81_RS24935	COG0531	amino acid
F6W81_RS24940	COG3030	protein affecting phage T7 exclusion by the F plasmid
F6W81_RS24945	COG1027	Aspartate ammonia-lyase
F6W81_RS24950	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F6W81_RS24965	COG1309	transcriptional regulator
F6W81_RS25005	COG0457	Tetratricopeptide repeat
F6W81_RS25010	COG0726	polysaccharide deacetylase
F6W81_RS25010	COG1649	PFAM Uncharacterised BCR, COG1649
F6W81_RS25015	COG1215	transferase activity, transferring glycosyl groups
F6W81_RS25035	COG0861	Integral membrane protein TerC family
F6W81_RS25070	COG1486	melibiose metabolic process
F6W81_RS25075	COG2169	Transcriptional regulator
F6W81_RS25090	COG2824	Alkylphosphonate utilization operon protein PhnA
F6W81_RS25095	COG2764	glyoxalase bleomycin resistance protein dioxygenase
F6W81_RS25100	COG2188	Transcriptional regulator
F6W81_RS25105	COG3624	Phosphonate C-P lyase system protein PhnG
F6W81_RS25110	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F6W81_RS25115	COG3626	phosphonate metabolism
F6W81_RS25120	COG3627	carbon phosphorus lyase activity
F6W81_RS25125	COG4107	phosphonate C-P lyase system protein PhnK
F6W81_RS25130	COG4778	phosphonate C-P lyase system protein PhnL
F6W81_RS25135	COG3454	Phosphonate metabolism
F6W81_RS25145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F6W81_RS25155	COG4191	Histidine kinase
F6W81_RS25155	COG0784	Response regulator, receiver
F6W81_RS25160	COG1129	ABC transporter
F6W81_RS25165	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS25200	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F6W81_RS25205	COG1301	dicarboxylic acid transport
F6W81_RS25215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F6W81_RS25220	COG3162	membrane
F6W81_RS25250	COG3539	Fimbrial protein
F6W81_RS25255	COG1346	cytolysis
F6W81_RS25260	COG1380	Effector of murein hydrolase LrgA
F6W81_RS25265	COG0583	DNA-binding transcription factor activity
F6W81_RS25270	COG0025	NhaP-type Na H and K H
F6W81_RS25275	COG2252	PERMEase
F6W81_RS25280	COG0625	glutathione transferase activity
F6W81_RS25285	COG0789	Transcriptional regulator
F6W81_RS25295	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F6W81_RS25330	COG1234	tRNA 3'-trailer cleavage
F6W81_RS25335	COG1609	Transcriptional regulator
F6W81_RS25340	COG0483	inositol monophosphate 1-phosphatase activity
F6W81_RS25355	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F6W81_RS25375	COG4771	TonB-dependent receptor
F6W81_RS25380	COG0741	lytic transglycosylase activity
F6W81_RS25395	COG2315	Protein conserved in bacteria
F6W81_RS25400	COG0432	Pfam Uncharacterised protein family UPF0047
F6W81_RS25415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F6W81_RS25420	COG0305	Participates in initiation and elongation during chromosome replication
F6W81_RS25435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F6W81_RS25445	COG0735	belongs to the Fur family
F6W81_RS25450	COG3237	CsbD-like
F6W81_RS25455	COG0534	Mate efflux family protein
F6W81_RS25465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F6W81_RS25535	COG0251	oxidation-reduction process
F6W81_RS25545	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F6W81_RS25555	COG0527	aspartate kinase activity
F6W81_RS25620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F6W81_RS25650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F6W81_RS25660	COG0456	acetyltransferase
F6W81_RS25695	COG0151	Belongs to the GarS family
F6W81_RS25705	COG4191	Histidine kinase
F6W81_RS25710	COG3678	ATP-independent chaperone mediated protein folding
F6W81_RS25745	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
F6W81_RS25760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F6W81_RS25765	COG2104	thiamine diphosphate biosynthetic process
F6W81_RS25780	COG3706	GGDEF domain
F6W81_RS25790	COG1447	Phosphotransferase system cellobiose-specific component IIA
F6W81_RS25795	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F6W81_RS25830	COG0250	Participates in transcription elongation, termination and antitermination
F6W81_RS25875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F6W81_RS25910	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
F6W81_RS25920	COG1739	Uncharacterized protein family UPF0029
F6W81_RS25960	COG0805	protein transport
F6W81_RS25980	COG3165	ubiquinone biosynthetic process from chorismate
F6W81_RS26010	COG0583	DNA-binding transcription factor activity
F6W81_RS26015	COG0697	spore germination
F6W81_RS26020	COG0561	phosphatase activity
F6W81_RS26025	COG2267	carboxylic ester hydrolase activity
F6W81_RS26030	COG1280	lysine exporter protein (LysE YggA)
F6W81_RS26040	COG1280	lysine exporter protein (LysE YggA)
F6W81_RS26070	COG0210	DNA helicase
F6W81_RS26075	COG1011	Hydrolase
F6W81_RS26105	COG3072	Adenylate cyclase
F6W81_RS26120	COG2959	enzyme of heme biosynthesis
F6W81_RS26125	COG3071	HemY protein
F6W81_RS26170	COG2244	polysaccharide biosynthetic process
F6W81_RS26175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F6W81_RS26180	COG0456	acetyltransferase
F6W81_RS26185	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F6W81_RS26190	COG1088	dTDP-glucose 4,6-dehydratase activity
F6W81_RS26195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F6W81_RS26200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F6W81_RS26210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F6W81_RS26215	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F6W81_RS26225	COG3118	belongs to the thioredoxin family
F6W81_RS26250	COG1811	Na channel or pump
F6W81_RS26260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F6W81_RS26265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F6W81_RS26275	COG0583	DNA-binding transcription factor activity
F6W81_RS26280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F6W81_RS26295	COG3978	acetolactate synthase activity
F6W81_RS26315	COG3085	chromosome segregation
F6W81_RS26390	COG0583	DNA-binding transcription factor activity
F6W81_RS26405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F6W81_RS26420	COG3443	Belongs to the bacterial solute-binding protein 9 family
F6W81_RS26425	COG2207	Transcriptional regulator
F6W81_RS26435	COG0371	Dehydrogenase
F6W81_RS26440	COG0697	spore germination
F6W81_RS26450	COG0583	DNA-binding transcription factor activity
F6W81_RS26460	COG0737	Belongs to the 5'-nucleotidase family
F6W81_RS26470	COG0460	homoserine dehydrogenase
F6W81_RS26470	COG0527	aspartate kinase activity
F6W81_RS26475	COG0626	cystathionine gamma-synthase activity
F6W81_RS26490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F6W81_RS26495	COG1609	Transcriptional regulator
F6W81_RS26500	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F6W81_RS26515	COG1575	Belongs to the MenA family. Type 1 subfamily
F6W81_RS26535	COG3678	ATP-independent chaperone mediated protein folding
F6W81_RS26540	COG0745	RESPONSE REGULATOR receiver
F6W81_RS26545	COG2205	protein histidine kinase activity
F6W81_RS26550	COG2258	MOSC domain
F6W81_RS26555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F6W81_RS26600	COG1129	ABC transporter
F6W81_RS26605	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS26610	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS26615	COG1454	alcohol dehydrogenase
F6W81_RS26625	COG2211	Major facilitator Superfamily
F6W81_RS26685	COG0205	6-phosphofructokinase activity
F6W81_RS26705	COG0437	4 iron, 4 sulfur cluster binding
F6W81_RS26710	COG2864	formate dehydrogenase
F6W81_RS26725	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F6W81_RS26730	COG0657	acetylesterase activity
F6W81_RS26735	COG0456	acetyltransferase
F6W81_RS26750	COG1011	Hydrolase
F6W81_RS26765	COG3852	Histidine kinase
F6W81_RS26780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F6W81_RS26805	COG0204	Acyl-transferase
F6W81_RS26815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F6W81_RS26820	COG3084	Protein conserved in bacteria
F6W81_RS26830	COG1763	Mo-molybdopterin cofactor biosynthetic process
F6W81_RS26860	COG2186	Transcriptional regulator
F6W81_RS26865	COG0477	Major facilitator Superfamily
F6W81_RS26870	COG1609	Transcriptional regulator
F6W81_RS26875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F6W81_RS26885	COG1172	Belongs to the binding-protein-dependent transport system permease family
F6W81_RS26890	COG1129	ABC transporter
F6W81_RS26920	COG1522	sequence-specific DNA binding
F6W81_RS26925	COG0716	FMN binding
F6W81_RS26940	COG3312	ion transport
F6W81_RS26995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F6W81_RS27000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F6W81_RS27005	COG0573	inorganic phosphate transmembrane transporter activity
F6W81_RS27010	COG0581	inorganic phosphate transmembrane transporter activity
F6W81_RS27015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F6W81_RS27020	COG0704	Plays a role in the regulation of phosphate uptake
F6W81_RS27045	COG2382	esterase
F6W81_RS27050	COG0363	glucosamine-6-phosphate deaminase activity
F6W81_RS27055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F6W81_RS27065	COG2252	PERMEase
F6W81_RS27070	COG0431	NADPH-dependent FMN reductase
F6W81_RS27075	COG2091	lysine biosynthetic process via aminoadipic acid
F6W81_RS27105	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F6W81_RS27370	COG3344	reverse transcriptase
F6W81_RS27460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F6W81_RS27730	COG3344	reverse transcriptase
F6W81_RS27950	COG3300	MHYT domain
F6W81_RS27950	COG5001	Diguanylate cyclase
F6W81_RS28030	COG3039	Transposase
F6W81_RS28090	COG2135	peptidase activity
F6W81_RS28245	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
F6W81_RS28345	COG3064	Membrane