locus-tag	class	description
B8O09_RS00015	COG0009	L-threonylcarbamoyladenylate synthase
B8O09_RS00025	COG0583	DNA-binding transcription factor activity
B8O09_RS00135	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
B8O09_RS00140	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS00150	COG0616	signal peptide processing
B8O09_RS00185	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B8O09_RS00195	COG0671	phosphoesterase, PA-phosphatase related
B8O09_RS00200	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
B8O09_RS00205	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B8O09_RS00215	COG0023	Translation Initiation Factor
B8O09_RS00225	COG1349	DNA-binding transcription factor activity
B8O09_RS00240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B8O09_RS00240	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B8O09_RS00245	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B8O09_RS00255	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B8O09_RS00270	COG4171	peptide transport system, permease
B8O09_RS00285	COG0702	epimerase
B8O09_RS00300	COG1473	amidohydrolase
B8O09_RS00310	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B8O09_RS00315	COG1842	Phage shock protein A
B8O09_RS00325	COG1983	PspC domain protein
B8O09_RS00335	COG3106	COG3106 Predicted ATPase
B8O09_RS00345	COG0583	DNA-binding transcription factor activity
B8O09_RS00350	COG1486	melibiose metabolic process
B8O09_RS00360	COG3180	Ammonia monooxygenase
B8O09_RS00365	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B8O09_RS00370	COG4948	Mandelate Racemase Muconate Lactonizing
B8O09_RS00375	COG2866	Carboxypeptidase
B8O09_RS00380	COG4166	transmembrane transport
B8O09_RS00410	COG0656	L-ascorbic acid biosynthetic process
B8O09_RS00430	COG0583	DNA-binding transcription factor activity
B8O09_RS00435	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS00440	COG1078	dGTPase activity
B8O09_RS00445	COG0693	protein deglycase activity
B8O09_RS00470	COG2885	chlorophyll binding
B8O09_RS00580	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS00585	COG1309	transcriptional regulator
B8O09_RS00590	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS00610	COG0583	DNA-binding transcription factor activity
B8O09_RS00635	COG0604	alcohol dehydrogenase
B8O09_RS00640	COG0436	Aminotransferase
B8O09_RS00655	COG2011	ABC-type metal ion transport system permease component
B8O09_RS00660	COG1448	Aminotransferase
B8O09_RS00670	COG1522	sequence-specific DNA binding
B8O09_RS00675	COG1113	amino acid transport
B8O09_RS00690	COG0673	inositol 2-dehydrogenase activity
B8O09_RS00695	COG1349	DNA-binding transcription factor activity
B8O09_RS00715	COG0513	Belongs to the DEAD box helicase family
B8O09_RS00725	COG0589	response to stress
B8O09_RS00735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B8O09_RS00740	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B8O09_RS00740	COG1013	pyruvate-flavodoxin oxidoreductase activity
B8O09_RS00740	COG0674	pyruvate-flavodoxin oxidoreductase activity
B8O09_RS00740	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B8O09_RS00750	COG3042	response to heat
B8O09_RS00755	COG3187	Heat shock protein
B8O09_RS00760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B8O09_RS00765	COG0586	Pfam SNARE associated Golgi protein
B8O09_RS00770	COG2911	Protein conserved in bacteria
B8O09_RS00780	COG3784	Protein of unknown function (DUF1318)
B8O09_RS00785	COG2207	Transcriptional regulator
B8O09_RS00790	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS00805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B8O09_RS00815	COG1126	abc transporter atp-binding protein
B8O09_RS00820	COG0583	DNA-binding transcription factor activity
B8O09_RS00825	COG2072	flavoprotein involved in K transport
B8O09_RS00840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B8O09_RS00870	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS00870	COG2030	dehydratase
B8O09_RS00875	COG3396	Phenylacetate-CoA oxygenase
B8O09_RS00880	COG3460	Phenylacetate-CoA oxygenase
B8O09_RS00885	COG3396	Phenylacetate-CoA oxygenase
B8O09_RS00890	COG2151	metal-sulfur cluster biosynthetic enzyme
B8O09_RS00895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B8O09_RS00900	COG1024	Enoyl-CoA hydratase
B8O09_RS00905	COG1024	Enoyl-CoA hydratase
B8O09_RS00910	COG1250	3-hydroxyacyl-CoA dehydrogenase
B8O09_RS00915	COG2050	protein possibly involved in aromatic compounds catabolism
B8O09_RS00920	COG0183	Belongs to the thiolase family
B8O09_RS00925	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
B8O09_RS00930	COG3327	negative regulation of DNA-templated transcription, initiation
B8O09_RS00935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B8O09_RS00950	COG1643	Atp-dependent helicase
B8O09_RS00955	COG4122	O-methyltransferase activity
B8O09_RS00980	COG0583	DNA-binding transcription factor activity
B8O09_RS00985	COG0667	Aldo Keto reductase
B8O09_RS00990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B8O09_RS00995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B8O09_RS01000	COG3138	arginine N-succinyltransferase
B8O09_RS01005	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS01010	COG3724	N-succinylarginine dihydrolase activity
B8O09_RS01015	COG2988	succinylglutamate desuccinylase activity
B8O09_RS01020	COG1113	amino acid transport
B8O09_RS01025	COG0477	Major facilitator Superfamily
B8O09_RS01030	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B8O09_RS01035	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS01040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B8O09_RS01045	COG0401	homolog of Blt101
B8O09_RS01050	COG5562	phage envelope protein
B8O09_RS01055	COG0425	Belongs to the sulfur carrier protein TusA family
B8O09_RS01060	COG2391	methyltransferase activity
B8O09_RS01085	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B8O09_RS01090	COG1263	PTS System
B8O09_RS01090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B8O09_RS01095	COG1609	Transcriptional regulator
B8O09_RS01100	COG5339	Protein conserved in bacteria
B8O09_RS01105	COG1482	cell wall glycoprotein biosynthetic process
B8O09_RS01110	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B8O09_RS01110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B8O09_RS01120	COG0114	fumarate hydratase activity
B8O09_RS01130	COG2205	protein histidine kinase activity
B8O09_RS01140	COG0745	RESPONSE REGULATOR receiver
B8O09_RS01145	COG3136	membrane protein required for alginate biosynthesis
B8O09_RS01155	COG0531	amino acid
B8O09_RS01175	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B8O09_RS01180	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
B8O09_RS01195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B8O09_RS01210	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
B8O09_RS01285	COG1846	Transcriptional regulator
B8O09_RS01335	COG4725	Belongs to the MT-A70-like family
B8O09_RS01360	COG3772	lysozyme
B8O09_RS01385	COG1783	phage Terminase large subunit
B8O09_RS01460	COG1388	LysM domain
B8O09_RS01460	COG0741	lytic transglycosylase activity
B8O09_RS01505	COG5301	cellulose 1,4-beta-cellobiosidase activity
B8O09_RS01510	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B8O09_RS01545	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
B8O09_RS01550	COG1473	amidohydrolase
B8O09_RS01560	COG0583	DNA-binding transcription factor activity
B8O09_RS01565	COG2840	Smr protein MutS2
B8O09_RS01570	COG1414	Transcriptional regulator
B8O09_RS01580	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B8O09_RS01585	COG0183	Belongs to the thiolase family
B8O09_RS01595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B8O09_RS01600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B8O09_RS01615	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B8O09_RS01615	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B8O09_RS01640	COG4565	transcriptional regulatory protein
B8O09_RS01645	COG3290	protein histidine kinase activity
B8O09_RS01685	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B8O09_RS01695	COG0679	Auxin Efflux Carrier
B8O09_RS01725	COG0628	permease
B8O09_RS01750	COG3591	Belongs to the peptidase S1B family
B8O09_RS01765	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B8O09_RS01770	COG2814	Major facilitator Superfamily
B8O09_RS01775	COG0583	DNA-binding transcription factor activity
B8O09_RS01780	COG1940	carbohydrate kinase activity
B8O09_RS01785	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B8O09_RS01800	COG3302	dmso reductase anchor subunit
B8O09_RS01805	COG0437	4 iron, 4 sulfur cluster binding
B8O09_RS01825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B8O09_RS01840	COG2271	Major facilitator Superfamily
B8O09_RS01845	COG0246	Mannitol dehydrogenase
B8O09_RS01850	COG0589	response to stress
B8O09_RS01855	COG1802	Transcriptional regulator
B8O09_RS01860	COG4221	oxidoreductase activity
B8O09_RS01875	COG2207	Transcriptional regulator
B8O09_RS01880	COG2135	peptidase activity
B8O09_RS01885	COG2197	response regulator
B8O09_RS01900	COG0071	Belongs to the small heat shock protein (HSP20) family
B8O09_RS01905	COG1546	Belongs to the CinA family
B8O09_RS01910	COG2200	EAL domain
B8O09_RS01925	COG3708	Transcriptional regulator
B8O09_RS01925	COG2207	Transcriptional regulator
B8O09_RS01930	COG2610	gluconate transmembrane transporter activity
B8O09_RS01935	COG3622	Belongs to the hyi family
B8O09_RS01940	COG0235	Class ii aldolase
B8O09_RS01945	COG3395	kinase activity
B8O09_RS01950	COG2084	Dehydrogenase
B8O09_RS01955	COG1349	DNA-binding transcription factor activity
B8O09_RS01970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B8O09_RS01975	COG2223	nitrite transmembrane transporter activity
B8O09_RS02010	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B8O09_RS02015	COG0683	leucine binding
B8O09_RS02030	COG1129	ABC transporter
B8O09_RS02035	COG0410	ABC transporter
B8O09_RS02045	COG2814	Major facilitator Superfamily
B8O09_RS02050	COG0697	spore germination
B8O09_RS02060	COG4977	sequence-specific DNA binding
B8O09_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS02090	COG2731	YhcH YjgK YiaL family protein
B8O09_RS02105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B8O09_RS02115	COG3395	kinase activity
B8O09_RS02120	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B8O09_RS02125	COG1349	DNA-binding transcription factor activity
B8O09_RS02130	COG0039	L-malate dehydrogenase activity
B8O09_RS02140	COG0583	DNA-binding transcription factor activity
B8O09_RS02145	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS02160	COG2199	diguanylate cyclase activity
B8O09_RS02205	COG0840	transmembrane signaling receptor activity
B8O09_RS02235	COG0477	Major facilitator Superfamily
B8O09_RS02245	COG2070	2-Nitropropane dioxygenase
B8O09_RS02250	COG2011	ABC-type metal ion transport system permease component
B8O09_RS02270	COG4628	conserved protein (DUF2132)
B8O09_RS02285	COG2207	Transcriptional regulator
B8O09_RS02315	COG2233	PERMEase
B8O09_RS02320	COG3648	Uricase
B8O09_RS02320	COG3195	allantoin biosynthetic process
B8O09_RS02325	COG2351	hydroxyisourate hydrolase activity
B8O09_RS02330	COG1396	sequence-specific DNA binding
B8O09_RS02335	COG3550	peptidyl-serine autophosphorylation
B8O09_RS02340	COG1649	PFAM Uncharacterised BCR, COG1649
B8O09_RS02355	COG3188	usher protein
B8O09_RS02390	COG5001	Diguanylate cyclase
B8O09_RS02390	COG3300	MHYT domain
B8O09_RS02395	COG2819	hydrolase of the alpha beta superfamily
B8O09_RS02405	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS02405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS02410	COG2814	Major facilitator Superfamily
B8O09_RS02420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B8O09_RS02420	COG1263	PTS System
B8O09_RS02425	COG2186	Transcriptional regulator
B8O09_RS02445	COG3835	regulator
B8O09_RS02450	COG1929	Belongs to the glycerate kinase type-1 family
B8O09_RS02495	COG0738	Major facilitator superfamily
B8O09_RS02500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B8O09_RS02505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B8O09_RS02510	COG1349	DNA-binding transcription factor activity
B8O09_RS02520	COG1070	Carbohydrate kinase
B8O09_RS02530	COG4977	sequence-specific DNA binding
B8O09_RS02550	COG4977	sequence-specific DNA binding
B8O09_RS02570	COG0667	Aldo Keto reductase
B8O09_RS02575	COG3386	PFAM SMP-30 Gluconolaconase
B8O09_RS02580	COG0667	Aldo Keto reductase
B8O09_RS02585	COG0667	Aldo Keto reductase
B8O09_RS02595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B8O09_RS02595	COG0456	acetyltransferase
B8O09_RS02625	COG1652	LysM domain
B8O09_RS02655	COG1609	Transcriptional regulator
B8O09_RS02665	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS02680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B8O09_RS02690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B8O09_RS02695	COG0583	DNA-binding transcription factor activity
B8O09_RS02700	COG0583	DNA-binding transcription factor activity
B8O09_RS02715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B8O09_RS02715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B8O09_RS02715	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B8O09_RS02720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B8O09_RS02730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B8O09_RS02735	COG3037	sugar-specific permease SgaT UlaA
B8O09_RS02745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS02750	COG1609	Transcriptional regulator
B8O09_RS02760	COG2223	nitrite transmembrane transporter activity
B8O09_RS02800	COG0477	Major facilitator Superfamily
B8O09_RS02805	COG4529	Protein conserved in bacteria
B8O09_RS02810	COG1902	pentaerythritol trinitrate reductase activity
B8O09_RS02820	COG0583	DNA-binding transcription factor activity
B8O09_RS02825	COG2070	2-Nitropropane dioxygenase
B8O09_RS02835	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B8O09_RS02845	COG0765	amino acid transport
B8O09_RS02890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B8O09_RS02900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B8O09_RS02920	COG2207	Transcriptional regulator
B8O09_RS02935	COG0406	alpha-ribazole phosphatase activity
B8O09_RS02970	COG1953	Uracil, thiamine, allantoin
B8O09_RS02975	COG0402	S-adenosylhomocysteine deaminase activity
B8O09_RS02995	COG3706	GGDEF domain
B8O09_RS03000	COG1609	Transcriptional regulator
B8O09_RS03010	COG0673	inositol 2-dehydrogenase activity
B8O09_RS03025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B8O09_RS03030	COG1116	anion transmembrane transporter activity
B8O09_RS03035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B8O09_RS03040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B8O09_RS03045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B8O09_RS03050	COG0076	glutamate decarboxylase activity
B8O09_RS03065	COG2205	protein histidine kinase activity
B8O09_RS03075	COG0596	Alpha beta hydrolase
B8O09_RS03115	COG0519	Catalyzes the synthesis of GMP from XMP
B8O09_RS03115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B8O09_RS03135	COG0583	DNA-binding transcription factor activity
B8O09_RS03145	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B8O09_RS03150	COG1285	pathogenesis
B8O09_RS03160	COG2814	Major facilitator Superfamily
B8O09_RS03165	COG1447	Phosphotransferase system cellobiose-specific component IIA
B8O09_RS03170	COG0583	DNA-binding transcription factor activity
B8O09_RS03175	COG0243	molybdopterin cofactor binding
B8O09_RS03180	COG3781	membrane
B8O09_RS03205	COG1764	response to oxidative stress
B8O09_RS03215	COG3111	PFAM Bacterial OB fold (BOF) protein
B8O09_RS03225	COG2323	membrane
B8O09_RS03235	COG0366	Alpha amylase catalytic
B8O09_RS03245	COG3685	Protein conserved in bacteria
B8O09_RS03265	COG3729	General stress protein
B8O09_RS03270	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS03310	COG0488	(ABC) transporter
B8O09_RS03325	COG1064	alcohol dehydrogenase
B8O09_RS03330	COG0747	negative chemotaxis
B8O09_RS03340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B8O09_RS03350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B8O09_RS03360	COG2814	Major facilitator Superfamily
B8O09_RS03370	COG2326	polyphosphate kinase activity
B8O09_RS03385	COG2864	formate dehydrogenase
B8O09_RS03390	COG0437	4 iron, 4 sulfur cluster binding
B8O09_RS03415	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
B8O09_RS03425	COG3485	protocatechuate 3,4-dioxygenase
B8O09_RS03430	COG4829	muconolactone delta-isomerase
B8O09_RS03435	COG4948	Mandelate Racemase Muconate Lactonizing
B8O09_RS03440	COG1414	Transcriptional regulator
B8O09_RS03460	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B8O09_RS03465	COG1140	nitrate reductase beta subunit
B8O09_RS03470	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B8O09_RS03475	COG2181	nitrate reductase activity
B8O09_RS03485	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B8O09_RS03490	COG1178	ABC-type Fe3 transport system permease component
B8O09_RS03495	COG1840	ABC-type Fe3 transport system, periplasmic component
B8O09_RS03500	COG3842	ATPase activity
B8O09_RS03505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B8O09_RS03520	COG2211	Major facilitator Superfamily
B8O09_RS03550	COG0625	glutathione transferase activity
B8O09_RS03560	COG1126	abc transporter atp-binding protein
B8O09_RS03565	COG0765	amino acid transport
B8O09_RS03575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B8O09_RS03580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B8O09_RS03585	COG1473	amidohydrolase
B8O09_RS03590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B8O09_RS03595	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B8O09_RS03620	COG4772	TonB-dependent receptor
B8O09_RS03625	COG1228	amidohydrolase
B8O09_RS03630	COG3691	Protein conserved in bacteria
B8O09_RS03645	COG2130	NADP-dependent
B8O09_RS03655	COG1247	-acetyltransferase
B8O09_RS03660	COG3238	Protein conserved in bacteria
B8O09_RS03670	COG0747	negative chemotaxis
B8O09_RS03675	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS03710	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS03715	COG1177	transmembrane transport
B8O09_RS03720	COG1176	ABC-type spermidine putrescine transport system, permease component I
B8O09_RS03725	COG3842	ATPase activity
B8O09_RS03730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B8O09_RS03735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B8O09_RS03740	COG1271	oxidase subunit
B8O09_RS03745	COG1294	oxidase, subunit
B8O09_RS03765	COG0826	peptidase U32
B8O09_RS03775	COG1396	sequence-specific DNA binding
B8O09_RS03780	COG3135	benzoate transporter
B8O09_RS03785	COG3708	Transcriptional regulator
B8O09_RS03785	COG2207	Transcriptional regulator
B8O09_RS03805	COG0500	methyltransferase
B8O09_RS03810	COG1275	C4-dicarboxylate transporter malic acid transport protein
B8O09_RS03815	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B8O09_RS03820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B8O09_RS03835	COG2272	Belongs to the type-B carboxylesterase lipase family
B8O09_RS03840	COG5383	Protein conserved in bacteria
B8O09_RS03845	COG3485	protocatechuate 3,4-dioxygenase
B8O09_RS03850	COG3485	protocatechuate 3,4-dioxygenase
B8O09_RS03855	COG0583	DNA-binding transcription factor activity
B8O09_RS03875	COG3038	cytochrome b561
B8O09_RS03895	COG2814	Major facilitator Superfamily
B8O09_RS03905	COG0673	inositol 2-dehydrogenase activity
B8O09_RS03915	COG2723	6-phospho-beta-galactosidase activity
B8O09_RS03950	COG4659	FMN binding
B8O09_RS03960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B8O09_RS03975	COG0625	glutathione transferase activity
B8O09_RS03980	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
B8O09_RS03995	COG3895	Periplasmic Protein
B8O09_RS04010	COG3706	GGDEF domain
B8O09_RS04025	COG1566	PFAM secretion protein HlyD family protein
B8O09_RS04030	COG1289	transmembrane transporter activity
B8O09_RS04035	COG2032	superoxide dismutase activity
B8O09_RS04040	COG4989	oxidoreductase activity
B8O09_RS04045	COG3313	Fe-S protein
B8O09_RS04050	COG1309	transcriptional regulator
B8O09_RS04055	COG1902	pentaerythritol trinitrate reductase activity
B8O09_RS04060	COG0346	lactoylglutathione lyase activity
B8O09_RS04070	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B8O09_RS04075	COG0791	NLP P60 protein
B8O09_RS04090	COG2814	Major facilitator Superfamily
B8O09_RS04100	COG0583	DNA-binding transcription factor activity
B8O09_RS04105	COG2814	Major facilitator Superfamily
B8O09_RS04110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B8O09_RS04115	COG0307	riboflavin synthase, alpha
B8O09_RS04170	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B8O09_RS04200	COG1349	DNA-binding transcription factor activity
B8O09_RS04205	COG0346	lactoylglutathione lyase activity
B8O09_RS04230	COG0444	Belongs to the ABC transporter superfamily
B8O09_RS04235	COG4608	Belongs to the ABC transporter superfamily
B8O09_RS04265	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS04265	COG3321	synthase
B8O09_RS04265	COG0604	alcohol dehydrogenase
B8O09_RS04310	COG0402	S-adenosylhomocysteine deaminase activity
B8O09_RS04335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B8O09_RS04340	COG0277	FAD linked oxidase domain protein
B8O09_RS04355	COG2814	Major facilitator Superfamily
B8O09_RS04385	COG0583	DNA-binding transcription factor activity
B8O09_RS04395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B8O09_RS04405	COG1250	3-hydroxyacyl-CoA dehydrogenase
B8O09_RS04410	COG2610	gluconate transmembrane transporter activity
B8O09_RS04415	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS04450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B8O09_RS04470	COG0745	RESPONSE REGULATOR receiver
B8O09_RS04475	COG3850	Histidine kinase
B8O09_RS04475	COG5002	protein histidine kinase activity
B8O09_RS04490	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
B8O09_RS04520	COG4235	cytochrome complex assembly
B8O09_RS04520	COG3088	subunit of a heme lyase
B8O09_RS04525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B8O09_RS04530	COG1138	Cytochrome C-type biogenesis protein
B8O09_RS04545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B8O09_RS04550	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B8O09_RS04555	COG4133	protoheme IX ABC transporter activity
B8O09_RS04585	COG1175	transmembrane transport
B8O09_RS04600	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B8O09_RS04605	COG3383	formate dehydrogenase (NAD+) activity
B8O09_RS04610	COG1473	amidohydrolase
B8O09_RS04640	COG1126	abc transporter atp-binding protein
B8O09_RS04645	COG0765	amino acid transport
B8O09_RS04665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B8O09_RS04670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B8O09_RS04675	COG1120	ATPase activity
B8O09_RS04680	COG4774	siderophore transport
B8O09_RS04685	COG1116	anion transmembrane transporter activity
B8O09_RS04690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B8O09_RS04710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B8O09_RS04715	COG0583	DNA-binding transcription factor activity
B8O09_RS04735	COG2814	Major facilitator Superfamily
B8O09_RS04770	COG1414	Transcriptional regulator
B8O09_RS04775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B8O09_RS04780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B8O09_RS04785	COG1120	ATPase activity
B8O09_RS04795	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B8O09_RS04800	COG2271	Major facilitator Superfamily
B8O09_RS04805	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B8O09_RS04805	COG1082	Xylose isomerase domain protein TIM barrel
B8O09_RS04810	COG1309	transcriptional regulator
B8O09_RS04835	COG1376	ErfK ybiS ycfS ynhG family protein
B8O09_RS04850	COG0719	Fe-S assembly protein
B8O09_RS04855	COG0396	ATPase activity
B8O09_RS04860	COG0719	Fe-S assembly protein
B8O09_RS04865	COG0316	Belongs to the HesB IscA family
B8O09_RS04880	COG1309	transcriptional regulator
B8O09_RS04885	COG1304	FMN binding
B8O09_RS04910	COG0583	DNA-binding transcription factor activity
B8O09_RS04920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B8O09_RS04925	COG1120	ATPase activity
B8O09_RS04955	COG2261	transglycosylase associated protein
B8O09_RS04960	COG2050	protein possibly involved in aromatic compounds catabolism
B8O09_RS04965	COG0277	FAD linked oxidase domain protein
B8O09_RS04965	COG0247	lactate metabolic process
B8O09_RS04970	COG0628	permease
B8O09_RS04980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B8O09_RS04980	COG0574	Belongs to the PEP-utilizing enzyme family
B8O09_RS04995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B8O09_RS05000	COG4256	Hemin uptake protein
B8O09_RS05010	COG0791	NLP P60 protein
B8O09_RS05020	COG0386	Belongs to the glutathione peroxidase family
B8O09_RS05040	COG0583	DNA-binding transcription factor activity
B8O09_RS05060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B8O09_RS05060	COG0072	phenylalanine-tRNA ligase activity
B8O09_RS05100	COG3137	Salt-induced outer membrane protein
B8O09_RS05105	COG1105	Belongs to the carbohydrate kinase PfkB family
B8O09_RS05115	COG3001	Fructosamine kinase
B8O09_RS05125	COG2350	Protein conserved in bacteria
B8O09_RS05130	COG2353	YceI-like domain
B8O09_RS05150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B8O09_RS05160	COG0444	Belongs to the ABC transporter superfamily
B8O09_RS05165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B8O09_RS05170	COG0601	transmembrane transport
B8O09_RS05175	COG4166	transmembrane transport
B8O09_RS05180	COG2095	MarC family integral membrane protein
B8O09_RS05190	COG1454	alcohol dehydrogenase
B8O09_RS05190	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS05195	COG1435	thymidine kinase activity
B8O09_RS05200	COG2916	Histone family protein nucleoid-structuring protein H-NS
B8O09_RS05205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B8O09_RS05210	COG0745	RESPONSE REGULATOR receiver
B8O09_RS05215	COG1752	Esterase of the alpha-beta hydrolase superfamily
B8O09_RS05225	COG0788	formyltetrahydrofolate deformylase activity
B8O09_RS05260	COG1522	sequence-specific DNA binding
B8O09_RS05270	COG2181	nitrate reductase activity
B8O09_RS05275	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B8O09_RS05280	COG1140	nitrate reductase beta subunit
B8O09_RS05285	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B8O09_RS05290	COG2223	nitrite transmembrane transporter activity
B8O09_RS05295	COG3850	Histidine kinase
B8O09_RS05300	COG2197	response regulator
B8O09_RS05305	COG4932	domain protein
B8O09_RS05310	COG0243	molybdopterin cofactor binding
B8O09_RS05315	COG2146	nitrite reductase [NAD(P)H] activity
B8O09_RS05315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B8O09_RS05320	COG1116	anion transmembrane transporter activity
B8O09_RS05330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B8O09_RS05335	COG3707	response regulator
B8O09_RS05340	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
B8O09_RS05350	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
B8O09_RS05355	COG4572	Cation transport regulator
B8O09_RS05360	COG0387	Pfam Sodium calcium exchanger
B8O09_RS05380	COG2890	protein-(glutamine-N5) methyltransferase activity
B8O09_RS05415	COG0659	secondary active sulfate transmembrane transporter activity
B8O09_RS05435	COG0012	GTP binding
B8O09_RS05520	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B8O09_RS05525	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B8O09_RS05595	COG2885	chlorophyll binding
B8O09_RS05625	COG3122	Protein conserved in bacteria
B8O09_RS05640	COG0583	DNA-binding transcription factor activity
B8O09_RS05670	COG0583	DNA-binding transcription factor activity
B8O09_RS05700	COG1882	Formate acetyltransferase
B8O09_RS05715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B8O09_RS05720	COG0583	DNA-binding transcription factor activity
B8O09_RS05760	COG2308	Evidence 4 Homologs of previously reported genes of
B8O09_RS05770	COG4774	siderophore transport
B8O09_RS05780	COG1619	proteins homologs of microcin C7 resistance protein MccF
B8O09_RS05920	COG4695	Portal protein
B8O09_RS05995	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B8O09_RS06020	COG2719	SpoVR family
B8O09_RS06050	COG0179	Fumarylacetoacetate (FAA) hydrolase
B8O09_RS06065	COG2894	cell division
B8O09_RS06075	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B8O09_RS06085	COG3065	identical protein binding
B8O09_RS06095	COG1199	ATP-dependent helicase activity
B8O09_RS06100	COG0251	oxidation-reduction process
B8O09_RS06120	COG1760	l-serine dehydratase
B8O09_RS06125	COG2200	EAL domain
B8O09_RS06130	COG1253	flavin adenine dinucleotide binding
B8O09_RS06135	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS06135	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B8O09_RS06140	COG3715	PTS system
B8O09_RS06145	COG3716	PTS system mannose fructose sorbose family IID component
B8O09_RS06165	COG2226	methyltransferase
B8O09_RS06170	COG0768	penicillin binding
B8O09_RS06210	COG1414	Transcriptional regulator
B8O09_RS06215	COG2814	Major facilitator Superfamily
B8O09_RS06235	COG1956	GAF domain-containing protein
B8O09_RS06240	COG2995	paraquat-inducible protein a
B8O09_RS06245	COG3008	intermembrane lipid transfer
B8O09_RS06270	COG2990	Protein conserved in bacteria
B8O09_RS06285	COG1276	copper resistance
B8O09_RS06290	COG2372	response to copper ion
B8O09_RS06300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B8O09_RS06305	COG1770	oligopeptidase
B8O09_RS06310	COG2979	Protein of unknown function (DUF533)
B8O09_RS06315	COG3141	response to X-ray
B8O09_RS06325	COG0800	Aldolase
B8O09_RS06330	COG0129	dihydroxy-acid dehydratase activity
B8O09_RS06335	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B8O09_RS06360	COG1560	Kdo2-lipid A biosynthetic process
B8O09_RS06365	COG0739	heme binding
B8O09_RS06370	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
B8O09_RS06380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B8O09_RS06405	COG0494	nUDIX hydrolase
B8O09_RS06415	COG1335	isochorismatase
B8O09_RS06420	COG1801	Protein of unknown function DUF72
B8O09_RS06425	COG3788	relative of glutathione S-transferase, MAPEG superfamily
B8O09_RS06445	COG3102	Protein conserved in bacteria
B8O09_RS06455	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B8O09_RS06480	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS06490	COG1879	ABC-type sugar transport system periplasmic component
B8O09_RS06500	COG1528	Iron-storage protein
B8O09_RS06510	COG2211	Major facilitator Superfamily
B8O09_RS06520	COG0477	Major facilitator Superfamily
B8O09_RS06535	COG1528	Iron-storage protein
B8O09_RS06545	COG0814	amino acid
B8O09_RS06550	COG3012	SEC-C Motif Domain Protein
B8O09_RS06550	COG3318	Belongs to the UPF0149 family
B8O09_RS06565	COG3772	lysozyme
B8O09_RS06595	COG3039	Transposase
B8O09_RS06740	COG0305	Participates in initiation and elongation during chromosome replication
B8O09_RS06765	COG3620	sequence-specific DNA binding
B8O09_RS06830	COG2197	response regulator
B8O09_RS06840	COG2197	response regulator
B8O09_RS06845	COG1126	abc transporter atp-binding protein
B8O09_RS06850	COG0765	amino acid transport
B8O09_RS06860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B8O09_RS06865	COG0366	Alpha amylase catalytic
B8O09_RS06895	COG2354	Protein conserved in bacteria
B8O09_RS06900	COG0697	spore germination
B8O09_RS06905	COG3727	T/G mismatch-specific endonuclease activity
B8O09_RS06910	COG0270	DNA (cytosine-5-)-methyltransferase activity
B8O09_RS06915	COG1418	mRNA catabolic process
B8O09_RS06925	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B8O09_RS06975	COG0025	NhaP-type Na H and K H
B8O09_RS06980	COG1309	transcriptional regulator
B8O09_RS06985	COG0604	alcohol dehydrogenase
B8O09_RS07005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B8O09_RS07015	COG0534	Mate efflux family protein
B8O09_RS07030	COG3706	GGDEF domain
B8O09_RS07055	COG3615	Tellurite resistance protein tehB
B8O09_RS07065	COG3300	MHYT domain
B8O09_RS07065	COG5001	Diguanylate cyclase
B8O09_RS07080	COG0477	Major facilitator Superfamily
B8O09_RS07085	COG0095	Lipoate-protein ligase
B8O09_RS07090	COG0583	DNA-binding transcription factor activity
B8O09_RS07095	COG1942	4-Oxalocrotonate Tautomerase
B8O09_RS07105	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B8O09_RS07125	COG1289	transmembrane transporter activity
B8O09_RS07140	COG2925	Exonuclease
B8O09_RS07150	COG0640	Transcriptional regulator
B8O09_RS07155	COG0531	amino acid
B8O09_RS07160	COG0583	DNA-binding transcription factor activity
B8O09_RS07165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B8O09_RS07190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B8O09_RS07215	COG0463	Glycosyl transferase, family 2
B8O09_RS07225	COG1442	glycosyl transferase family 8
B8O09_RS07225	COG1216	Glycosyl transferase, family 2
B8O09_RS07230	COG0438	transferase activity, transferring glycosyl groups
B8O09_RS07285	COG1088	dTDP-glucose 4,6-dehydratase activity
B8O09_RS07300	COG0463	Glycosyl transferase, family 2
B8O09_RS07305	COG2244	polysaccharide biosynthetic process
B8O09_RS07330	COG0463	Glycosyl transferase, family 2
B8O09_RS07330	COG1216	Glycosyl transferase, family 2
B8O09_RS07380	COG1253	flavin adenine dinucleotide binding
B8O09_RS07385	COG2982	Protein involved in outer membrane biogenesis
B8O09_RS07400	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B8O09_RS07405	COG0443	Heat shock 70 kDa protein
B8O09_RS07410	COG5002	protein histidine kinase activity
B8O09_RS07425	COG1301	dicarboxylic acid transport
B8O09_RS07450	COG2205	protein histidine kinase activity
B8O09_RS07455	COG0745	RESPONSE REGULATOR receiver
B8O09_RS07460	COG0826	peptidase U32
B8O09_RS07470	COG4608	Belongs to the ABC transporter superfamily
B8O09_RS07475	COG0444	Belongs to the ABC transporter superfamily
B8O09_RS07480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B8O09_RS07485	COG0601	transmembrane transport
B8O09_RS07490	COG0747	negative chemotaxis
B8O09_RS07495	COG4948	Mandelate Racemase Muconate Lactonizing
B8O09_RS07500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B8O09_RS07510	COG1070	Carbohydrate kinase
B8O09_RS07535	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B8O09_RS07545	COG1830	Aldolase
B8O09_RS07550	COG0351	phosphomethylpyrimidine kinase
B8O09_RS07565	COG0583	DNA-binding transcription factor activity
B8O09_RS07575	COG2252	PERMEase
B8O09_RS07580	COG0583	DNA-binding transcription factor activity
B8O09_RS07585	COG5455	response to cobalt ion
B8O09_RS07605	COG4807	Protein conserved in bacteria
B8O09_RS07625	COG1174	glycine betaine transport
B8O09_RS07630	COG1125	glycine betaine transport
B8O09_RS07635	COG1174	glycine betaine transport
B8O09_RS07640	COG1732	Glycine betaine
B8O09_RS07645	COG1472	Belongs to the glycosyl hydrolase 3 family
B8O09_RS07650	COG0277	FAD linked oxidase domain protein
B8O09_RS07660	COG1686	Belongs to the peptidase S11 family
B8O09_RS07670	COG0586	Pfam SNARE associated Golgi protein
B8O09_RS07675	COG1538	Outer membrane efflux protein
B8O09_RS07680	COG2723	6-phospho-beta-galactosidase activity
B8O09_RS07695	COG3659	wide pore channel activity
B8O09_RS07700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B8O09_RS07710	COG1346	cytolysis
B8O09_RS07720	COG2949	membrane
B8O09_RS07730	COG1129	ABC transporter
B8O09_RS07745	COG2311	Membrane
B8O09_RS07760	COG4771	TonB-dependent receptor
B8O09_RS07770	COG0833	amino acid
B8O09_RS07775	COG0583	DNA-binding transcription factor activity
B8O09_RS07785	COG2855	membrane
B8O09_RS07795	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B8O09_RS07795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B8O09_RS07795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B8O09_RS07800	COG1105	Belongs to the carbohydrate kinase PfkB family
B8O09_RS07805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS07805	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS07835	COG1312	Catalyzes the dehydration of D-mannonate
B8O09_RS07840	COG0246	Mannitol dehydrogenase
B8O09_RS07845	COG0523	cobalamin synthesis protein
B8O09_RS07850	COG0671	phosphoesterase, PA-phosphatase related
B8O09_RS07855	COG0791	NLP P60 protein
B8O09_RS07860	COG2200	EAL domain
B8O09_RS07865	COG4166	transmembrane transport
B8O09_RS07870	COG4174	ABC transporter (Permease)
B8O09_RS07875	COG4239	(ABC) transporter, permease
B8O09_RS07880	COG4172	Belongs to the ABC transporter superfamily
B8O09_RS07890	COG2814	Major facilitator Superfamily
B8O09_RS07895	COG1187	pseudouridine synthase activity
B8O09_RS07900	COG1061	Type III restriction enzyme res subunit
B8O09_RS07920	COG0494	nUDIX hydrolase
B8O09_RS07925	COG1349	DNA-binding transcription factor activity
B8O09_RS07950	COG0628	permease
B8O09_RS07965	COG0659	secondary active sulfate transmembrane transporter activity
B8O09_RS07970	COG2239	Acts as a magnesium transporter
B8O09_RS07975	COG4615	Cyclic peptide transporter
B8O09_RS07980	COG3145	DNA-N1-methyladenine dioxygenase activity
B8O09_RS07985	COG2169	Transcriptional regulator
B8O09_RS07985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B8O09_RS08000	COG0642	Histidine kinase
B8O09_RS08000	COG2198	Histidine kinase
B8O09_RS08010	COG2205	protein histidine kinase activity
B8O09_RS08010	COG0784	Response regulator, receiver
B8O09_RS08040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B8O09_RS08050	COG0584	glycerophosphoryl diester phosphodiesterase
B8O09_RS08055	COG2271	Major facilitator Superfamily
B8O09_RS08060	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B8O09_RS08070	COG0247	lactate metabolic process
B8O09_RS08080	COG2271	Major facilitator Superfamily
B8O09_RS08090	COG1414	Transcriptional regulator
B8O09_RS08105	COG5464	transposase or invertase
B8O09_RS08115	COG0318	PFAM AMP-dependent synthetase and ligase
B8O09_RS08140	COG1169	isochorismate synthase
B8O09_RS08145	COG2153	protein acetylation
B8O09_RS08160	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B8O09_RS08165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B8O09_RS08175	COG0839	Belongs to the complex I subunit 6 family
B8O09_RS08225	COG0583	DNA-binding transcription factor activity
B8O09_RS08230	COG0436	Aminotransferase
B8O09_RS08240	COG0490	domain, Protein
B8O09_RS08240	COG0471	metal ion transport
B8O09_RS08245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B8O09_RS08265	COG0280	phosphate acetyltransferase
B8O09_RS08265	COG0857	belongs to the CobB CobQ family
B8O09_RS08270	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B8O09_RS08275	COG0622	Phosphoesterase
B8O09_RS08280	COG0625	glutathione transferase activity
B8O09_RS08285	COG0625	glutathione transferase activity
B8O09_RS08290	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B8O09_RS08295	COG1090	epimerase
B8O09_RS08305	COG4598	ABC transporter
B8O09_RS08310	COG4160	amino acid transport
B8O09_RS08330	COG0163	prenyltransferase activity
B8O09_RS08335	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B8O09_RS08340	COG1286	toxin biosynthetic process
B8O09_RS08345	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
B8O09_RS08350	COG0285	dihydrofolate synthase activity
B8O09_RS08360	COG0586	Pfam SNARE associated Golgi protein
B8O09_RS08370	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B8O09_RS08390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B8O09_RS08405	COG3101	peptidyl-lysine hydroxylation
B8O09_RS08410	COG0730	response to heat
B8O09_RS08435	COG2062	phosphohistidine phosphatase, SixA
B8O09_RS08450	COG3691	Protein conserved in bacteria
B8O09_RS08460	COG2853	Lipoprotein
B8O09_RS08465	COG2116	formate transmembrane transporter activity
B8O09_RS08555	COG1403	HNH endonuclease
B8O09_RS08560	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B8O09_RS08570	COG1846	Transcriptional regulator
B8O09_RS08660	COG0583	DNA-binding transcription factor activity
B8O09_RS08665	COG0590	tRNA wobble adenosine to inosine editing
B8O09_RS08670	COG2807	transmembrane transport
B8O09_RS08675	COG0436	Aminotransferase
B8O09_RS08685	COG3275	phosphorelay sensor kinase activity
B8O09_RS08690	COG3279	Response regulator of the LytR AlgR family
B8O09_RS08705	COG3961	Belongs to the TPP enzyme family
B8O09_RS08710	COG0667	Aldo Keto reductase
B8O09_RS08725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B8O09_RS08730	COG2199	diguanylate cyclase activity
B8O09_RS08730	COG2200	EAL domain
B8O09_RS08745	COG3415	Transposase
B8O09_RS08750	COG3415	Transposase
B8O09_RS08780	COG0583	DNA-binding transcription factor activity
B8O09_RS08785	COG0385	Bile acid
B8O09_RS08790	COG3530	Putative quorum-sensing-regulated virulence factor
B8O09_RS08810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B8O09_RS08845	COG4319	ketosteroid isomerase
B8O09_RS08855	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B8O09_RS08860	COG4208	sulfate ABC transporter
B8O09_RS08865	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B8O09_RS08870	COG4150	thiosulfate binding
B8O09_RS08880	COG2837	iron assimilation
B8O09_RS08900	COG0860	N-Acetylmuramoyl-L-alanine amidase
B8O09_RS08990	COG4810	utilization protein
B8O09_RS09000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B8O09_RS09005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B8O09_RS09010	COG5342	invasion associated locus B
B8O09_RS09020	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B8O09_RS09020	COG0493	'glutamate synthase
B8O09_RS09030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B8O09_RS09035	COG1393	Belongs to the ArsC family
B8O09_RS09050	COG0400	carboxylic ester hydrolase activity
B8O09_RS09055	COG1444	tRNA N-acetyltransferase activity
B8O09_RS09060	COG2321	neutral zinc metallopeptidase
B8O09_RS09070	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
B8O09_RS09080	COG2716	regulation of RNA biosynthetic process
B8O09_RS09085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B8O09_RS09090	COG0628	permease
B8O09_RS09095	COG4783	chaperone-mediated protein folding
B8O09_RS09100	COG1393	Belongs to the ArsC family
B8O09_RS09115	COG2233	PERMEase
B8O09_RS09125	COG2723	6-phospho-beta-galactosidase activity
B8O09_RS09140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B8O09_RS09155	COG2200	EAL domain
B8O09_RS09175	COG0641	radical SAM
B8O09_RS09180	COG3119	arylsulfatase activity
B8O09_RS09190	COG0516	GMP reductase activity
B8O09_RS09190	COG0517	IMP dehydrogenase activity
B8O09_RS09200	COG1645	bacterial-type flagellum-dependent swarming motility
B8O09_RS09320	COG2976	Protein conserved in bacteria
B8O09_RS09350	COG4953	penicillin-binding protein 1C
B8O09_RS09355	COG2373	Large extracellular alpha-helical protein
B8O09_RS09360	COG2897	thiosulfate sulfurtransferase activity
B8O09_RS09380	COG2975	iron-sulfur cluster assembly
B8O09_RS09385	COG0633	Ferredoxin
B8O09_RS09405	COG0822	iron-sulfur transferase activity
B8O09_RS09435	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
B8O09_RS09440	COG3683	transport system, periplasmic component
B8O09_RS09445	COG3711	transcriptional antiterminator
B8O09_RS09450	COG2814	Major facilitator Superfamily
B8O09_RS09455	COG2017	converts alpha-aldose to the beta-anomer
B8O09_RS09460	COG0477	Major facilitator Superfamily
B8O09_RS09460	COG2814	Major facilitator Superfamily
B8O09_RS09465	COG0457	Tetratricopeptide repeat
B8O09_RS09470	COG1940	carbohydrate kinase activity
B8O09_RS09475	COG2259	Doxx family
B8O09_RS09490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B8O09_RS09490	COG1017	nitric oxide dioxygenase activity
B8O09_RS09495	COG0347	Belongs to the P(II) protein family
B8O09_RS09500	COG2204	response regulator
B8O09_RS09505	COG3170	Tfp pilus assembly protein FimV
B8O09_RS09510	COG2205	protein histidine kinase activity
B8O09_RS09515	COG0047	phosphoribosylformylglycinamidine synthase activity
B8O09_RS09515	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B8O09_RS09530	COG0560	Phosphoserine phosphatase
B8O09_RS09535	COG1737	Transcriptional regulator
B8O09_RS09540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B8O09_RS09550	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B8O09_RS09570	COG0681	Belongs to the peptidase S26 family
B8O09_RS09580	COG3086	response to oxidative stress
B8O09_RS09585	COG3026	antisigma factor binding
B8O09_RS09590	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
B8O09_RS09600	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B8O09_RS09610	COG0513	Belongs to the DEAD box helicase family
B8O09_RS09625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B8O09_RS09635	COG3118	belongs to the thioredoxin family
B8O09_RS09640	COG3148	PFAM DTW domain containing protein
B8O09_RS09650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B8O09_RS09655	COG5544	Lipoprotein
B8O09_RS09660	COG0477	Major facilitator Superfamily
B8O09_RS09685	COG0542	response to heat
B8O09_RS09700	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B8O09_RS09705	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B8O09_RS09710	COG1605	Chorismate mutase
B8O09_RS09710	COG0077	Prephenate dehydratase
B8O09_RS09720	COG1605	Chorismate mutase
B8O09_RS09720	COG0287	Prephenate dehydrogenase
B8O09_RS09725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B8O09_RS09735	COG2199	diguanylate cyclase activity
B8O09_RS09740	COG2885	chlorophyll binding
B8O09_RS09775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B8O09_RS09780	COG4137	Cytochrome C assembly protein
B8O09_RS09785	COG4536	flavin adenine dinucleotide binding
B8O09_RS09805	COG0497	DNA recombination
B8O09_RS09820	COG2867	negative regulation of translational initiation
B8O09_RS09895	COG2207	Transcriptional regulator
B8O09_RS09895	COG3708	Transcriptional regulator
B8O09_RS09900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B8O09_RS09935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B8O09_RS09945	COG0235	Class ii aldolase
B8O09_RS09955	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS09970	COG2197	response regulator
B8O09_RS09975	COG3539	Fimbrial protein
B8O09_RS09985	COG3188	usher protein
B8O09_RS10005	COG3121	Chaperone
B8O09_RS10010	COG3539	Fimbrial protein
B8O09_RS10020	COG3284	Transcriptional regulator
B8O09_RS10025	COG0583	DNA-binding transcription factor activity
B8O09_RS10035	COG0640	Transcriptional regulator
B8O09_RS10040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B8O09_RS10055	COG2916	Histone family protein nucleoid-structuring protein H-NS
B8O09_RS10080	COG4575	ribosome binding
B8O09_RS10085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B8O09_RS10090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B8O09_RS10095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B8O09_RS10105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B8O09_RS10120	COG4176	ABC-type proline glycine betaine transport system permease component
B8O09_RS10130	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B8O09_RS10140	COG1846	Transcriptional regulator
B8O09_RS10145	COG1566	PFAM secretion protein HlyD family protein
B8O09_RS10150	COG2814	Major facilitator Superfamily
B8O09_RS10155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B8O09_RS10175	COG1238	metal cluster binding
B8O09_RS10180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B8O09_RS10185	COG2823	Periplasmic or secreted lipoprotein
B8O09_RS10210	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B8O09_RS10235	COG1546	Belongs to the CinA family
B8O09_RS10245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B8O09_RS10250	COG1121	(ABC) transporter
B8O09_RS10260	COG2951	lytic endotransglycosylase activity
B8O09_RS10265	COG3730	PTS system glucitol sorbitol-specific
B8O09_RS10270	COG3732	PTS system glucitol sorbitol-specific
B8O09_RS10280	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS10285	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS10290	COG1349	DNA-binding transcription factor activity
B8O09_RS10320	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
B8O09_RS10325	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
B8O09_RS10330	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B8O09_RS10335	COG1609	Transcriptional regulator
B8O09_RS10340	COG1263	PTS System
B8O09_RS10340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B8O09_RS10345	COG2723	6-phospho-beta-galactosidase activity
B8O09_RS10355	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B8O09_RS10365	COG3260	NADH ubiquinone oxidoreductase 20
B8O09_RS10370	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B8O09_RS10375	COG3261	NADH dehydrogenase
B8O09_RS10375	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
B8O09_RS10380	COG0650	Formate hydrogenlyase subunit 4
B8O09_RS10385	COG0651	ATP synthesis coupled electron transport
B8O09_RS10390	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B8O09_RS10410	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B8O09_RS10415	COG0298	carbon dioxide binding
B8O09_RS10420	COG0409	Hydrogenase expression formation protein
B8O09_RS10425	COG0309	Hydrogenase expression formation protein (HypE)
B8O09_RS10435	COG2723	6-phospho-beta-galactosidase activity
B8O09_RS10445	COG4580	involved in the transport of maltose and maltodextrins
B8O09_RS10455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B8O09_RS10460	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B8O09_RS10465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B8O09_RS10470	COG1447	Phosphotransferase system cellobiose-specific component IIA
B8O09_RS10475	COG1940	carbohydrate kinase activity
B8O09_RS10480	COG1609	Transcriptional regulator
B8O09_RS10485	COG0803	Belongs to the bacterial solute-binding protein 9 family
B8O09_RS10490	COG1121	(ABC) transporter
B8O09_RS10495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B8O09_RS10500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B8O09_RS10515	COG0679	Auxin Efflux Carrier
B8O09_RS10535	COG3720	iron ion transport
B8O09_RS10540	COG4558	Periplasmic binding protein
B8O09_RS10545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B8O09_RS10585	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B8O09_RS10590	COG0163	prenyltransferase activity
B8O09_RS10615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B8O09_RS10620	COG4942	peptidase
B8O09_RS10620	COG1388	LysM domain
B8O09_RS10680	COG2234	aminopeptidase activity
B8O09_RS10700	COG0720	synthase
B8O09_RS10705	COG0602	queuosine metabolic process
B8O09_RS10725	COG3956	TIGRFAM MazG family protein
B8O09_RS10730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B8O09_RS10740	COG4999	Histidine kinase
B8O09_RS10740	COG3850	Histidine kinase
B8O09_RS10740	COG3437	response regulator, receiver
B8O09_RS10740	COG2205	protein histidine kinase activity
B8O09_RS10745	COG1929	Belongs to the glycerate kinase type-1 family
B8O09_RS10750	COG4948	Mandelate Racemase Muconate Lactonizing
B8O09_RS10755	COG4948	Mandelate Racemase Muconate Lactonizing
B8O09_RS10760	COG2271	Major facilitator Superfamily
B8O09_RS10765	COG0716	FMN binding
B8O09_RS10770	COG0564	pseudouridine synthase activity
B8O09_RS10775	COG3098	single-species biofilm formation
B8O09_RS10790	COG1611	Belongs to the LOG family
B8O09_RS10795	COG0814	amino acid
B8O09_RS10800	COG1760	l-serine dehydratase
B8O09_RS10805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B8O09_RS10815	COG0477	Major facilitator Superfamily
B8O09_RS10825	COG1464	Belongs to the NlpA lipoprotein family
B8O09_RS10830	COG2011	ABC-type metal ion transport system permease component
B8O09_RS10835	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B8O09_RS10850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B8O09_RS10865	COG1454	alcohol dehydrogenase
B8O09_RS10870	COG0235	Class ii aldolase
B8O09_RS10875	COG0738	Major facilitator superfamily
B8O09_RS10895	COG1349	DNA-binding transcription factor activity
B8O09_RS10905	COG2363	Small membrane protein
B8O09_RS10910	COG0583	DNA-binding transcription factor activity
B8O09_RS10920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B8O09_RS10925	COG2166	iron-sulfur cluster assembly
B8O09_RS10930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B8O09_RS10935	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
B8O09_RS11100	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
B8O09_RS11130	COG1454	alcohol dehydrogenase
B8O09_RS11130	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS11135	COG4656	Part of a membrane complex involved in electron transport
B8O09_RS11165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B8O09_RS11170	COG0860	N-Acetylmuramoyl-L-alanine amidase
B8O09_RS11175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B8O09_RS11175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B8O09_RS11185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B8O09_RS11190	COG1074	ATP-dependent DNA helicase activity
B8O09_RS11195	COG1025	Belongs to the peptidase M16 family
B8O09_RS11200	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B8O09_RS11205	COG4967	type IV pilus modification protein PilV
B8O09_RS11215	COG4795	General secretion pathway protein
B8O09_RS11220	COG2165	general secretion pathway protein
B8O09_RS11250	COG0861	Integral membrane protein TerC family
B8O09_RS11260	COG0667	Aldo Keto reductase
B8O09_RS11285	COG1609	Transcriptional regulator
B8O09_RS11295	COG2186	Transcriptional regulator
B8O09_RS11300	COG2723	6-phospho-beta-galactosidase activity
B8O09_RS11305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B8O09_RS11310	COG1609	Transcriptional regulator
B8O09_RS11320	COG0583	DNA-binding transcription factor activity
B8O09_RS11325	COG1794	racemase activity, acting on amino acids and derivatives
B8O09_RS11330	COG1917	Cupin 2, conserved barrel domain protein
B8O09_RS11335	COG1175	transmembrane transport
B8O09_RS11340	COG0395	ABC-type sugar transport system, permease component
B8O09_RS11345	COG3842	ATPase activity
B8O09_RS11375	COG2814	Major facilitator Superfamily
B8O09_RS11380	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS11385	COG0823	Involved in the tonB-independent uptake of proteins
B8O09_RS11395	COG0183	Belongs to the thiolase family
B8O09_RS11410	COG0814	amino acid
B8O09_RS11415	COG0667	Aldo Keto reductase
B8O09_RS11465	COG0697	spore germination
B8O09_RS11470	COG1846	Transcriptional regulator
B8O09_RS11475	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
B8O09_RS11490	COG0582	viral genome integration into host DNA
B8O09_RS11495	COG4974	Belongs to the 'phage' integrase family
B8O09_RS11505	COG3539	Fimbrial protein
B8O09_RS11510	COG3121	Chaperone
B8O09_RS11515	COG3188	usher protein
B8O09_RS11520	COG3539	Fimbrial protein
B8O09_RS11525	COG3539	Fimbrial protein
B8O09_RS11530	COG3539	Fimbrial protein
B8O09_RS11540	COG2388	GCN5-related N-acetyl-transferase
B8O09_RS11545	COG3592	Divergent 4Fe-4S mono-cluster
B8O09_RS11560	COG1289	transmembrane transporter activity
B8O09_RS11565	COG1538	Outer membrane efflux protein
B8O09_RS11580	COG1393	Belongs to the ArsC family
B8O09_RS11585	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B8O09_RS11620	COG0667	Aldo Keto reductase
B8O09_RS11635	COG2814	Major facilitator Superfamily
B8O09_RS11645	COG4942	peptidase
B8O09_RS11670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B8O09_RS11680	COG4974	Belongs to the 'phage' integrase family
B8O09_RS11685	COG0716	FMN binding
B8O09_RS11695	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B8O09_RS11705	COG1272	protein, Hemolysin III
B8O09_RS11715	COG1737	Transcriptional regulator
B8O09_RS11720	COG2723	6-phospho-beta-galactosidase activity
B8O09_RS11740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B8O09_RS11745	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS11765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B8O09_RS11770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B8O09_RS11775	COG0006	proline dipeptidase activity
B8O09_RS11795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B8O09_RS11800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B8O09_RS11815	COG2968	Membrane
B8O09_RS11825	COG0668	transmembrane transport
B8O09_RS11830	COG0191	fructose-bisphosphate aldolase activity
B8O09_RS11845	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B8O09_RS11850	COG0501	Belongs to the peptidase M48B family
B8O09_RS11870	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
B8O09_RS11875	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS11905	COG1414	Transcriptional regulator
B8O09_RS11910	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS11925	COG2146	nitrite reductase [NAD(P)H] activity
B8O09_RS11970	COG2814	Major facilitator Superfamily
B8O09_RS11980	COG2356	endonuclease I
B8O09_RS11985	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B8O09_RS11990	COG0189	ligase activity
B8O09_RS12010	COG2805	Type II/IV secretion system protein
B8O09_RS12015	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B8O09_RS12020	COG0762	integral membrane protein
B8O09_RS12035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B8O09_RS12045	COG3171	Protein conserved in bacteria
B8O09_RS12055	COG1194	a g-specific adenine glycosylase
B8O09_RS12070	COG2211	Major facilitator Superfamily
B8O09_RS12075	COG1982	Orn Lys Arg decarboxylase major
B8O09_RS12085	COG1811	Na channel or pump
B8O09_RS12125	COG0626	cystathionine gamma-synthase activity
B8O09_RS12130	COG0583	DNA-binding transcription factor activity
B8O09_RS12150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B8O09_RS12155	COG0754	glutathionylspermidine amidase activity
B8O09_RS12165	COG0625	glutathione transferase activity
B8O09_RS12190	COG2211	Major facilitator Superfamily
B8O09_RS12195	COG0848	biopolymer transport protein
B8O09_RS12210	COG0626	cystathionine gamma-synthase activity
B8O09_RS12215	COG0586	Pfam SNARE associated Golgi protein
B8O09_RS12220	COG2207	Transcriptional regulator
B8O09_RS12225	COG1979	alcohol dehydrogenase
B8O09_RS12230	COG0656	L-ascorbic acid biosynthetic process
B8O09_RS12240	COG1032	radical SAM domain protein
B8O09_RS12245	COG2132	Multicopper oxidase
B8O09_RS12250	COG0204	Acyl-transferase
B8O09_RS12255	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B8O09_RS12260	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B8O09_RS12265	COG3111	PFAM Bacterial OB fold (BOF) protein
B8O09_RS12275	COG0642	Histidine kinase
B8O09_RS12280	COG2249	NAD(P)H dehydrogenase (quinone) activity
B8O09_RS12285	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B8O09_RS12295	COG3150	esterase
B8O09_RS12300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B8O09_RS12305	COG3151	Protein conserved in bacteria
B8O09_RS12310	COG0494	nUDIX hydrolase
B8O09_RS12325	COG0754	glutathionylspermidine amidase activity
B8O09_RS12330	COG3384	dioxygenase
B8O09_RS12345	COG2960	long-chain fatty acid transporting porin activity
B8O09_RS12365	COG3025	triphosphatase activity
B8O09_RS12370	COG4991	sh3 domain protein
B8O09_RS12385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B8O09_RS12450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B8O09_RS12455	COG0358	DNA primase activity
B8O09_RS12460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B8O09_RS12485	COG2197	response regulator
B8O09_RS12490	COG2198	Histidine kinase
B8O09_RS12490	COG2205	protein histidine kinase activity
B8O09_RS12490	COG0784	Response regulator, receiver
B8O09_RS12490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B8O09_RS12500	COG3247	response to pH
B8O09_RS12580	COG2376	Dihydroxyacetone kinase
B8O09_RS12585	COG1461	Dihydroxyacetone kinase
B8O09_RS12600	COG2375	cellular response to nickel ion
B8O09_RS12605	COG1695	Transcriptional regulator
B8O09_RS12660	COG1902	pentaerythritol trinitrate reductase activity
B8O09_RS12660	COG0446	pyridine nucleotide-disulphide oxidoreductase
B8O09_RS12680	COG1451	nucleotide metabolic process
B8O09_RS12685	COG0673	inositol 2-dehydrogenase activity
B8O09_RS12690	COG0861	Integral membrane protein TerC family
B8O09_RS12705	COG2721	sulfolactate sulfo-lyase activity
B8O09_RS12715	COG2271	Major facilitator Superfamily
B8O09_RS12720	COG2186	Transcriptional regulator
B8O09_RS12725	COG0586	Pfam SNARE associated Golgi protein
B8O09_RS12735	COG1422	Protein of unknown function (DUF1090)
B8O09_RS12740	COG4575	ribosome binding
B8O09_RS12745	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
B8O09_RS12755	COG2259	Doxx family
B8O09_RS12760	COG0435	Glutathione S-transferase
B8O09_RS12765	COG3152	Membrane
B8O09_RS12770	COG0583	DNA-binding transcription factor activity
B8O09_RS12775	COG1741	Belongs to the pirin family
B8O09_RS12795	COG1929	Belongs to the glycerate kinase type-1 family
B8O09_RS12800	COG2084	Dehydrogenase
B8O09_RS12810	COG2271	Major facilitator Superfamily
B8O09_RS12815	COG2721	sulfolactate sulfo-lyase activity
B8O09_RS12820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B8O09_RS12825	COG1349	DNA-binding transcription factor activity
B8O09_RS12835	COG1105	Belongs to the carbohydrate kinase PfkB family
B8O09_RS12840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B8O09_RS12840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B8O09_RS12840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS12845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS12845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS12855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS12860	COG3414	Phosphotransferase system galactitol-specific IIB component
B8O09_RS12865	COG3775	system Galactitol-specific IIC component
B8O09_RS12870	COG1063	alcohol dehydrogenase
B8O09_RS12885	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B8O09_RS12905	COG2823	Periplasmic or secreted lipoprotein
B8O09_RS12910	COG0701	Predicted permease
B8O09_RS12915	COG0702	epimerase
B8O09_RS12920	COG0693	protein deglycase activity
B8O09_RS12935	COG3153	acetyltransferase
B8O09_RS12940	COG3154	lipid carrier protein
B8O09_RS12945	COG0826	peptidase U32
B8O09_RS12950	COG0826	peptidase U32
B8O09_RS12955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B8O09_RS12960	COG0814	amino acid
B8O09_RS13010	COG0195	Participates in both transcription termination and antitermination
B8O09_RS13050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B8O09_RS13060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B8O09_RS13065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B8O09_RS13080	COG1534	Rna-binding protein
B8O09_RS13090	COG2027	D-alanyl-D-alanine carboxypeptidase
B8O09_RS13100	COG0697	spore germination
B8O09_RS13115	COG0142	geranyltranstransferase activity
B8O09_RS13120	COG3423	Transcriptional regulator
B8O09_RS13130	COG5007	Belongs to the BolA IbaG family
B8O09_RS13135	COG3113	response to antibiotic
B8O09_RS13140	COG2854	intermembrane phospholipid transfer
B8O09_RS13145	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B8O09_RS13150	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B8O09_RS13155	COG1127	ABC transporter
B8O09_RS13165	COG0530	calcium, potassium:sodium antiporter activity
B8O09_RS13175	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B8O09_RS13180	COG3117	lipopolysaccharide transmembrane transporter activity
B8O09_RS13185	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
B8O09_RS13190	COG1137	ATPase activity
B8O09_RS13195	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B8O09_RS13200	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B8O09_RS13205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS13215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS13220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B8O09_RS13225	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
B8O09_RS13230	COG5002	protein histidine kinase activity
B8O09_RS13230	COG0784	Response regulator, receiver
B8O09_RS13230	COG2198	Histidine kinase
B8O09_RS13235	COG1312	Catalyzes the dehydration of D-mannonate
B8O09_RS13240	COG1063	alcohol dehydrogenase
B8O09_RS13245	COG2271	Major facilitator Superfamily
B8O09_RS13250	COG1242	4 iron, 4 sulfur cluster binding
B8O09_RS13260	COG0067	glutamate synthase
B8O09_RS13260	COG0069	glutamate synthase activity
B8O09_RS13260	COG0070	glutamate synthase
B8O09_RS13265	COG0493	'glutamate synthase
B8O09_RS13275	COG2969	positive regulation of protein catabolic process
B8O09_RS13280	COG0625	glutathione transferase activity
B8O09_RS13300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B8O09_RS13305	COG3105	Protein conserved in bacteria
B8O09_RS13310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B8O09_RS13315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B8O09_RS13340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B8O09_RS13345	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B8O09_RS13350	COG0471	metal ion transport
B8O09_RS13360	COG1802	Transcriptional regulator
B8O09_RS13385	COG2732	(Barnase) inhibitor
B8O09_RS13390	COG1289	transmembrane transporter activity
B8O09_RS13405	COG0583	DNA-binding transcription factor activity
B8O09_RS13410	COG0312	modulator of DNA gyrase
B8O09_RS13415	COG3164	Protein of unknown function
B8O09_RS13420	COG1530	ribonuclease E activity
B8O09_RS13430	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B8O09_RS13435	COG1792	Involved in formation and maintenance of cell shape
B8O09_RS13440	COG1077	Cell shape determining protein MreB Mrl
B8O09_RS13450	COG2200	EAL domain
B8O09_RS13450	COG2199	diguanylate cyclase activity
B8O09_RS13480	COG0511	ligase activity, forming carbon-carbon bonds
B8O09_RS13485	COG0439	Biotin carboxylase
B8O09_RS13490	COG3924	membrane
B8O09_RS13495	COG4145	pantothenate transmembrane transporter activity
B8O09_RS13525	COG1802	Transcriptional regulator
B8O09_RS13525	COG4626	Terminase
B8O09_RS13615	COG3561	AntA/AntB antirepressor
B8O09_RS13630	COG0582	viral genome integration into host DNA
B8O09_RS13635	COG1309	transcriptional regulator
B8O09_RS13640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B8O09_RS13645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B8O09_RS13680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B8O09_RS13700	COG0551	DNA topoisomerase type I activity
B8O09_RS13710	COG0758	DNA mediated transformation
B8O09_RS13740	COG3036	rescue of stalled ribosome
B8O09_RS13745	COG0789	Transcriptional regulator
B8O09_RS13760	COG0202	RNA polymerase activity
B8O09_RS13785	COG0201	protein transport
B8O09_RS13850	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B8O09_RS13865	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B8O09_RS13890	COG0051	transcription antitermination factor activity, RNA binding
B8O09_RS13945	COG2964	Protein conserved in bacteria
B8O09_RS13950	COG0545	Peptidyl-prolyl cis-trans isomerase
B8O09_RS13960	COG1047	Peptidyl-prolyl cis-trans
B8O09_RS13965	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
B8O09_RS13980	COG0488	(ABC) transporter
B8O09_RS13990	COG0429	hydrolase of the alpha beta-hydrolase fold
B8O09_RS14000	COG3954	Phosphoribulokinase
B8O09_RS14005	COG1765	OsmC-like protein
B8O09_RS14020	COG1289	transmembrane transporter activity
B8O09_RS14025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B8O09_RS14050	COG0738	Major facilitator superfamily
B8O09_RS14055	COG0402	S-adenosylhomocysteine deaminase activity
B8O09_RS14060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B8O09_RS14085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B8O09_RS14090	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B8O09_RS14095	COG3266	domain, Protein
B8O09_RS14115	COG4796	Type ii and iii secretion system protein
B8O09_RS14140	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B8O09_RS14145	COG0494	nUDIX hydrolase
B8O09_RS14155	COG1011	Hydrolase
B8O09_RS14160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B8O09_RS14185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B8O09_RS14190	COG2183	response to ionizing radiation
B8O09_RS14195	COG1918	ferrous iron import across plasma membrane
B8O09_RS14220	COG1040	competence protein
B8O09_RS14230	COG2610	gluconate transmembrane transporter activity
B8O09_RS14235	COG1640	4-alpha-glucanotransferase
B8O09_RS14240	COG0058	SHG alpha-glucan phosphorylase activity
B8O09_RS14255	COG1349	DNA-binding transcription factor activity
B8O09_RS14270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B8O09_RS14285	COG0058	SHG alpha-glucan phosphorylase activity
B8O09_RS14310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B8O09_RS14320	COG2610	gluconate transmembrane transporter activity
B8O09_RS14325	COG3265	gluconokinase activity
B8O09_RS14330	COG1609	Transcriptional regulator
B8O09_RS14335	COG1741	Belongs to the pirin family
B8O09_RS14340	COG0673	inositol 2-dehydrogenase activity
B8O09_RS14350	COG1247	-acetyltransferase
B8O09_RS14355	COG0405	Gamma-glutamyltransferase
B8O09_RS14365	COG0584	glycerophosphoryl diester phosphodiesterase
B8O09_RS14415	COG0559	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS14420	COG0683	leucine binding
B8O09_RS14430	COG0683	leucine binding
B8O09_RS14445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B8O09_RS14460	COG2177	Part of the ABC transporter FtsEX involved in
B8O09_RS14465	COG2884	Cell division ATP-binding protein ftsE
B8O09_RS14470	COG0552	protein localization to endoplasmic reticulum
B8O09_RS14475	COG0742	ribosomal rna small subunit methyltransferase
B8O09_RS14480	COG3776	membrane
B8O09_RS14490	COG3714	YhhN family
B8O09_RS14505	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B8O09_RS14515	COG0477	Major facilitator Superfamily
B8O09_RS14560	COG3479	Phenolic acid decarboxylase
B8O09_RS14570	COG0747	negative chemotaxis
B8O09_RS14575	COG0601	transmembrane transport
B8O09_RS14580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B8O09_RS14590	COG1124	(ABC) transporter
B8O09_RS14600	COG2239	Acts as a magnesium transporter
B8O09_RS14630	COG1196	nuclear chromosome segregation
B8O09_RS14635	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B8O09_RS14665	COG2081	HI0933 family
B8O09_RS14670	COG0306	phosphate transporter
B8O09_RS14680	COG0589	response to stress
B8O09_RS14700	COG0671	phosphoesterase, PA-phosphatase related
B8O09_RS14705	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B8O09_RS14710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B8O09_RS14720	COG1454	alcohol dehydrogenase
B8O09_RS14730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B8O09_RS14735	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS14740	COG0583	DNA-binding transcription factor activity
B8O09_RS14745	COG1295	ribonuclease BN
B8O09_RS14750	COG0477	Major facilitator Superfamily
B8O09_RS14755	COG2982	Protein involved in outer membrane biogenesis
B8O09_RS14770	COG0612	Peptidase, M16
B8O09_RS14780	COG2199	diguanylate cyclase activity
B8O09_RS14780	COG2200	EAL domain
B8O09_RS14785	COG0457	Tetratricopeptide repeat
B8O09_RS14785	COG3118	belongs to the thioredoxin family
B8O09_RS14790	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B8O09_RS14795	COG1215	transferase activity, transferring glycosyl groups
B8O09_RS14825	COG2194	sulfuric ester hydrolase activity
B8O09_RS14840	COG0457	Tetratricopeptide repeat
B8O09_RS14845	COG1215	transferase activity, transferring glycosyl groups
B8O09_RS14855	COG2894	cell division
B8O09_RS14870	COG4608	Belongs to the ABC transporter superfamily
B8O09_RS14875	COG0444	Belongs to the ABC transporter superfamily
B8O09_RS14880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B8O09_RS14885	COG0601	transmembrane transport
B8O09_RS14890	COG0747	negative chemotaxis
B8O09_RS14925	COG2223	nitrite transmembrane transporter activity
B8O09_RS14930	COG5571	outer membrane autotransporter
B8O09_RS14935	COG2818	Glycosylase
B8O09_RS14940	COG0456	acetyltransferase
B8O09_RS14945	COG0243	molybdopterin cofactor binding
B8O09_RS14950	COG2885	chlorophyll binding
B8O09_RS14955	COG1609	Transcriptional regulator
B8O09_RS14965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B8O09_RS14985	COG2814	Major facilitator Superfamily
B8O09_RS14990	COG2944	sequence-specific DNA binding
B8O09_RS14995	COG1278	Cold shock
B8O09_RS15040	COG3274	enterobacterial common antigen metabolic process
B8O09_RS15045	COG4682	membrane
B8O09_RS15050	COG4682	membrane
B8O09_RS15070	COG4213	ABC transporter substrate-binding protein
B8O09_RS15080	COG4214	carbohydrate transport
B8O09_RS15085	COG1609	Transcriptional regulator
B8O09_RS15085	COG2207	Transcriptional regulator
B8O09_RS15090	COG2992	FlgJ-related protein
B8O09_RS15100	COG0366	Alpha amylase catalytic
B8O09_RS15105	COG3977	Valine--pyruvate aminotransferase
B8O09_RS15110	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B8O09_RS15115	COG1414	Transcriptional regulator
B8O09_RS15120	COG3276	selenocysteine insertion sequence binding
B8O09_RS15130	COG0625	glutathione transferase activity
B8O09_RS15135	COG1566	PFAM secretion protein HlyD family protein
B8O09_RS15155	COG3722	fumarate hydratase activity
B8O09_RS15175	COG2186	Transcriptional regulator
B8O09_RS15185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B8O09_RS15205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B8O09_RS15210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B8O09_RS15220	COG4942	peptidase
B8O09_RS15225	COG2861	carbohydrate metabolic process
B8O09_RS15230	COG0463	Glycosyl transferase, family 2
B8O09_RS15240	COG0156	8-amino-7-oxononanoate synthase activity
B8O09_RS15255	COG0859	PFAM glycosyl transferase family 9
B8O09_RS15280	COG0859	PFAM glycosyl transferase family 9
B8O09_RS15290	COG0438	transferase activity, transferring glycosyl groups
B8O09_RS15295	COG1216	Glycosyl transferase, family 2
B8O09_RS15300	COG1519	Transferase
B8O09_RS15335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B8O09_RS15365	COG0842	Transport permease protein
B8O09_RS15370	COG1131	(ABC) transporter
B8O09_RS15390	COG1561	YicC-like family, N-terminal region
B8O09_RS15395	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B8O09_RS15400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B8O09_RS15400	COG2169	Transcriptional regulator
B8O09_RS15410	COG2860	membrane
B8O09_RS15430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B8O09_RS15435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B8O09_RS15440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B8O09_RS15445	COG1494	fructose-1,6-bisphosphatase
B8O09_RS15455	COG3152	Membrane
B8O09_RS15480	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B8O09_RS15500	COG0786	glutamate:sodium symporter activity
B8O09_RS15505	COG2233	PERMEase
B8O09_RS15510	COG2982	Protein involved in outer membrane biogenesis
B8O09_RS15515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B8O09_RS15515	COG1263	PTS System
B8O09_RS15520	COG1486	melibiose metabolic process
B8O09_RS15530	COG1501	Belongs to the glycosyl hydrolase 31 family
B8O09_RS15535	COG2211	Major facilitator Superfamily
B8O09_RS15570	COG1064	alcohol dehydrogenase
B8O09_RS15580	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B8O09_RS15595	COG1464	Belongs to the NlpA lipoprotein family
B8O09_RS15620	COG0583	DNA-binding transcription factor activity
B8O09_RS15655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B8O09_RS15665	COG2814	Major facilitator Superfamily
B8O09_RS15675	COG1263	PTS System
B8O09_RS15675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B8O09_RS15680	COG0697	spore germination
B8O09_RS15695	COG2828	Protein conserved in bacteria
B8O09_RS15700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B8O09_RS15705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B8O09_RS15710	COG0583	DNA-binding transcription factor activity
B8O09_RS15715	COG3384	dioxygenase
B8O09_RS15725	COG1609	Transcriptional regulator
B8O09_RS15735	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B8O09_RS15735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B8O09_RS15740	COG1447	Phosphotransferase system cellobiose-specific component IIA
B8O09_RS15745	COG4580	involved in the transport of maltose and maltodextrins
B8O09_RS15770	COG2188	Transcriptional regulator
B8O09_RS15820	COG2271	Major facilitator Superfamily
B8O09_RS15830	COG2197	response regulator
B8O09_RS15835	COG0440	acetolactate synthase activity
B8O09_RS15840	COG0028	Belongs to the TPP enzyme family
B8O09_RS15865	COG2814	Major facilitator Superfamily
B8O09_RS15870	COG0583	DNA-binding transcription factor activity
B8O09_RS15875	COG2610	gluconate transmembrane transporter activity
B8O09_RS15895	COG2149	membrane
B8O09_RS15910	COG2188	Transcriptional regulator
B8O09_RS15920	COG3645	SOS response
B8O09_RS15925	COG3645	SOS response
B8O09_RS15940	COG5645	(Lipo)protein
B8O09_RS15945	COG0823	Involved in the tonB-independent uptake of proteins
B8O09_RS15950	COG2271	Major facilitator Superfamily
B8O09_RS15960	COG0800	Aldolase
B8O09_RS15965	COG3734	2-keto-3-deoxy-galactonokinase
B8O09_RS15970	COG2186	Transcriptional regulator
B8O09_RS15985	COG0561	phosphatase activity
B8O09_RS15990	COG0187	DNA topoisomerase II activity
B8O09_RS16025	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B8O09_RS16055	COG2091	lysine biosynthetic process via aminoadipic acid
B8O09_RS16060	COG0431	NADPH-dependent FMN reductase
B8O09_RS16065	COG2252	PERMEase
B8O09_RS16075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B8O09_RS16080	COG0363	glucosamine-6-phosphate deaminase activity
B8O09_RS16085	COG2382	esterase
B8O09_RS16100	COG0704	Plays a role in the regulation of phosphate uptake
B8O09_RS16105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B8O09_RS16110	COG0581	inorganic phosphate transmembrane transporter activity
B8O09_RS16115	COG0573	inorganic phosphate transmembrane transporter activity
B8O09_RS16120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B8O09_RS16125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B8O09_RS16175	COG3312	ion transport
B8O09_RS16190	COG0716	FMN binding
B8O09_RS16195	COG1522	sequence-specific DNA binding
B8O09_RS16225	COG1129	ABC transporter
B8O09_RS16230	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS16240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B8O09_RS16245	COG1609	Transcriptional regulator
B8O09_RS16250	COG0477	Major facilitator Superfamily
B8O09_RS16255	COG2186	Transcriptional regulator
B8O09_RS16285	COG1763	Mo-molybdopterin cofactor biosynthetic process
B8O09_RS16295	COG3084	Protein conserved in bacteria
B8O09_RS16300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B8O09_RS16310	COG0204	Acyl-transferase
B8O09_RS16335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B8O09_RS16350	COG3852	Histidine kinase
B8O09_RS16370	COG1011	Hydrolase
B8O09_RS16385	COG0456	acetyltransferase
B8O09_RS16395	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B8O09_RS16410	COG2864	formate dehydrogenase
B8O09_RS16415	COG0437	4 iron, 4 sulfur cluster binding
B8O09_RS16440	COG0205	6-phosphofructokinase activity
B8O09_RS16500	COG2211	Major facilitator Superfamily
B8O09_RS16505	COG1609	Transcriptional regulator
B8O09_RS16510	COG2211	Major facilitator Superfamily
B8O09_RS16525	COG1454	alcohol dehydrogenase
B8O09_RS16530	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS16535	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS16540	COG1129	ABC transporter
B8O09_RS16585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B8O09_RS16590	COG2258	MOSC domain
B8O09_RS16595	COG2205	protein histidine kinase activity
B8O09_RS16600	COG0745	RESPONSE REGULATOR receiver
B8O09_RS16605	COG3678	ATP-independent chaperone mediated protein folding
B8O09_RS16625	COG1575	Belongs to the MenA family. Type 1 subfamily
B8O09_RS16640	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B8O09_RS16645	COG1609	Transcriptional regulator
B8O09_RS16650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B8O09_RS16665	COG0626	cystathionine gamma-synthase activity
B8O09_RS16670	COG0460	homoserine dehydrogenase
B8O09_RS16670	COG0527	aspartate kinase activity
B8O09_RS16680	COG0737	Belongs to the 5'-nucleotidase family
B8O09_RS16690	COG0583	DNA-binding transcription factor activity
B8O09_RS16700	COG0697	spore germination
B8O09_RS16705	COG0371	Dehydrogenase
B8O09_RS16715	COG2207	Transcriptional regulator
B8O09_RS16720	COG3443	Belongs to the bacterial solute-binding protein 9 family
B8O09_RS16735	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B8O09_RS16760	COG0583	DNA-binding transcription factor activity
B8O09_RS16835	COG3085	chromosome segregation
B8O09_RS16855	COG3978	acetolactate synthase activity
B8O09_RS16870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B8O09_RS16875	COG0583	DNA-binding transcription factor activity
B8O09_RS16885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B8O09_RS16890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B8O09_RS16900	COG1811	Na channel or pump
B8O09_RS16930	COG3118	belongs to the thioredoxin family
B8O09_RS16940	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B8O09_RS16945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B8O09_RS16955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B8O09_RS16960	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B8O09_RS16965	COG1088	dTDP-glucose 4,6-dehydratase activity
B8O09_RS16970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B8O09_RS16975	COG0456	acetyltransferase
B8O09_RS16980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B8O09_RS16985	COG2244	polysaccharide biosynthetic process
B8O09_RS17030	COG3071	HemY protein
B8O09_RS17035	COG2959	enzyme of heme biosynthesis
B8O09_RS17050	COG3072	Adenylate cyclase
B8O09_RS17080	COG1011	Hydrolase
B8O09_RS17085	COG0210	DNA helicase
B8O09_RS17120	COG1280	lysine exporter protein (LysE YggA)
B8O09_RS17130	COG1280	lysine exporter protein (LysE YggA)
B8O09_RS17135	COG2267	carboxylic ester hydrolase activity
B8O09_RS17140	COG0561	phosphatase activity
B8O09_RS17145	COG0697	spore germination
B8O09_RS17150	COG0583	DNA-binding transcription factor activity
B8O09_RS17180	COG3165	ubiquinone biosynthetic process from chorismate
B8O09_RS17200	COG0805	protein transport
B8O09_RS17245	COG1739	Uncharacterized protein family UPF0029
B8O09_RS17255	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
B8O09_RS17340	COG0250	Participates in transcription elongation, termination and antitermination
B8O09_RS17380	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B8O09_RS17385	COG1447	Phosphotransferase system cellobiose-specific component IIA
B8O09_RS17395	COG3706	GGDEF domain
B8O09_RS17415	COG2104	thiamine diphosphate biosynthetic process
B8O09_RS17420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B8O09_RS17435	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
B8O09_RS17470	COG3678	ATP-independent chaperone mediated protein folding
B8O09_RS17475	COG4191	Histidine kinase
B8O09_RS17485	COG0151	Belongs to the GarS family
B8O09_RS17520	COG0456	acetyltransferase
B8O09_RS17530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B8O09_RS17580	COG0527	aspartate kinase activity
B8O09_RS17595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B8O09_RS17605	COG0251	oxidation-reduction process
B8O09_RS17680	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B8O09_RS17690	COG0534	Mate efflux family protein
B8O09_RS17695	COG3237	CsbD-like
B8O09_RS17700	COG0735	belongs to the Fur family
B8O09_RS17710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B8O09_RS17725	COG0305	Participates in initiation and elongation during chromosome replication
B8O09_RS17730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B8O09_RS17745	COG0432	Pfam Uncharacterised protein family UPF0047
B8O09_RS17750	COG2315	Protein conserved in bacteria
B8O09_RS17765	COG0741	lytic transglycosylase activity
B8O09_RS17770	COG4771	TonB-dependent receptor
B8O09_RS17790	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B8O09_RS17805	COG0483	inositol monophosphate 1-phosphatase activity
B8O09_RS17810	COG1609	Transcriptional regulator
B8O09_RS17815	COG1234	tRNA 3'-trailer cleavage
B8O09_RS17850	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B8O09_RS17860	COG0789	Transcriptional regulator
B8O09_RS17865	COG0625	glutathione transferase activity
B8O09_RS17870	COG2252	PERMEase
B8O09_RS17875	COG0025	NhaP-type Na H and K H
B8O09_RS17880	COG0583	DNA-binding transcription factor activity
B8O09_RS17885	COG1380	Effector of murein hydrolase LrgA
B8O09_RS17890	COG1346	cytolysis
B8O09_RS17895	COG3539	Fimbrial protein
B8O09_RS17925	COG3162	membrane
B8O09_RS17935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B8O09_RS17945	COG1301	dicarboxylic acid transport
B8O09_RS17950	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
B8O09_RS17985	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS17990	COG1129	ABC transporter
B8O09_RS17995	COG0784	Response regulator, receiver
B8O09_RS17995	COG4191	Histidine kinase
B8O09_RS18005	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B8O09_RS18015	COG3454	Phosphonate metabolism
B8O09_RS18020	COG4778	phosphonate C-P lyase system protein PhnL
B8O09_RS18025	COG4107	phosphonate C-P lyase system protein PhnK
B8O09_RS18030	COG3627	carbon phosphorus lyase activity
B8O09_RS18035	COG3626	phosphonate metabolism
B8O09_RS18040	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
B8O09_RS18045	COG3624	Phosphonate C-P lyase system protein PhnG
B8O09_RS18050	COG2188	Transcriptional regulator
B8O09_RS18055	COG2764	glyoxalase bleomycin resistance protein dioxygenase
B8O09_RS18060	COG2824	Alkylphosphonate utilization operon protein PhnA
B8O09_RS18075	COG2169	Transcriptional regulator
B8O09_RS18085	COG1486	melibiose metabolic process
B8O09_RS18120	COG0861	Integral membrane protein TerC family
B8O09_RS18140	COG1215	transferase activity, transferring glycosyl groups
B8O09_RS18145	COG0726	polysaccharide deacetylase
B8O09_RS18145	COG1649	PFAM Uncharacterised BCR, COG1649
B8O09_RS18150	COG0457	Tetratricopeptide repeat
B8O09_RS18205	COG1309	transcriptional regulator
B8O09_RS18220	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B8O09_RS18225	COG1027	Aspartate ammonia-lyase
B8O09_RS18235	COG3030	protein affecting phage T7 exclusion by the F plasmid
B8O09_RS18240	COG0531	amino acid
B8O09_RS18305	COG1509	lysine 2,3-aminomutase activity
B8O09_RS18320	COG5510	response to toxic substance
B8O09_RS18325	COG2076	Multidrug Resistance protein
B8O09_RS18345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B8O09_RS18350	COG1053	succinate dehydrogenase
B8O09_RS18365	COG1511	domain protein
B8O09_RS18365	COG3264	Mechanosensitive ion channel
B8O09_RS18390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B8O09_RS18415	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B8O09_RS18420	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B8O09_RS18420	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B8O09_RS18425	COG0802	atpase or kinase
B8O09_RS18430	COG0860	N-Acetylmuramoyl-L-alanine amidase
B8O09_RS18450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B8O09_RS18455	COG0330	HflC and HflK could
B8O09_RS18460	COG0330	HflC and HflK could
B8O09_RS18470	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
B8O09_RS18485	COG0557	exoribonuclease II activity
B8O09_RS18490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B8O09_RS18495	COG1960	acyl-CoA dehydrogenase activity
B8O09_RS18505	COG3650	response to hydrogen peroxide
B8O09_RS18510	COG1073	alpha beta
B8O09_RS18570	COG2965	DNA replication, synthesis of RNA primer
B8O09_RS18575	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B8O09_RS18585	COG3061	Opacity-associated protein A
B8O09_RS18590	COG0545	Peptidyl-prolyl cis-trans isomerase
B8O09_RS18595	COG1113	amino acid transport
B8O09_RS18605	COG0697	spore germination
B8O09_RS18615	COG0702	epimerase
B8O09_RS18620	COG1733	regulation of RNA biosynthetic process
B8O09_RS18635	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
B8O09_RS18660	COG1253	flavin adenine dinucleotide binding
B8O09_RS18670	COG0729	surface antigen
B8O09_RS18675	COG2911	Protein conserved in bacteria
B8O09_RS18680	COG2105	PFAM AIG2 family protein
B8O09_RS18700	COG1879	ABC-type sugar transport system periplasmic component
B8O09_RS18705	COG1129	ABC transporter
B8O09_RS18710	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS18715	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS18725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B8O09_RS18750	COG0312	modulator of DNA gyrase
B8O09_RS18785	COG3964	amidohydrolase
B8O09_RS18800	COG2706	6-phosphogluconolactonase activity
B8O09_RS18805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS18805	COG3711	transcriptional antiterminator
B8O09_RS18810	COG3077	Addiction module antitoxin, RelB DinJ family
B8O09_RS18815	COG2026	Addiction module toxin, RelE StbE family
B8O09_RS18820	COG0602	queuosine metabolic process
B8O09_RS18840	COG1486	melibiose metabolic process
B8O09_RS18845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B8O09_RS18850	COG0366	Alpha amylase catalytic
B8O09_RS18855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B8O09_RS18855	COG1263	PTS System
B8O09_RS18895	COG2731	YhcH YjgK YiaL family protein
B8O09_RS18900	COG2222	sugar isomerase
B8O09_RS18905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B8O09_RS18910	COG1228	amidohydrolase
B8O09_RS18915	COG1288	antiporter activity
B8O09_RS18920	COG2188	Transcriptional regulator
B8O09_RS18945	COG0525	valine-tRNA ligase activity
B8O09_RS18950	COG2927	DNA polymerase III (CHI subunit)
B8O09_RS18965	COG0795	lipopolysaccharide-transporting ATPase activity
B8O09_RS18970	COG0795	lipopolysaccharide-transporting ATPase activity
B8O09_RS18975	COG0433	COG0433 Predicted ATPase
B8O09_RS18990	COG3718	enzyme involved in inositol metabolism
B8O09_RS19000	COG0837	glucose binding
B8O09_RS19000	COG1737	Transcriptional regulator
B8O09_RS19005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B8O09_RS19010	COG3962	Belongs to the TPP enzyme family
B8O09_RS19020	COG1082	Xylose isomerase domain protein TIM barrel
B8O09_RS19035	COG3842	ATPase activity
B8O09_RS19040	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B8O09_RS19045	COG0395	ABC-type sugar transport system, permease component
B8O09_RS19050	COG1175	transmembrane transport
B8O09_RS19055	COG1064	alcohol dehydrogenase
B8O09_RS19060	COG0659	secondary active sulfate transmembrane transporter activity
B8O09_RS19065	COG0288	reversible hydration of carbon dioxide
B8O09_RS19080	COG0582	viral genome integration into host DNA
B8O09_RS19105	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B8O09_RS19155	COG3596	GTP binding
B8O09_RS19160	COG2378	regulation of single-species biofilm formation
B8O09_RS19170	COG2378	regulation of single-species biofilm formation
B8O09_RS19195	COG2003	Belongs to the UPF0758 family
B8O09_RS19215	COG1715	Restriction endonuclease
B8O09_RS19225	COG2963	transposase activity
B8O09_RS19240	COG2801	Transposase and inactivated derivatives
B8O09_RS19245	COG2801	Transposase and inactivated derivatives
B8O09_RS19290	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
B8O09_RS19290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B8O09_RS19335	COG3507	Belongs to the glycosyl hydrolase 43 family
B8O09_RS19340	COG2211	Major facilitator Superfamily
B8O09_RS19345	COG2115	Belongs to the xylose isomerase family
B8O09_RS19350	COG4580	involved in the transport of maltose and maltodextrins
B8O09_RS19355	COG3272	Protein of unknown function (DUF1722)
B8O09_RS19375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B8O09_RS19390	COG0300	oxidoreductase activity
B8O09_RS19395	COG3631	Ketosteroid isomerase-related protein
B8O09_RS19400	COG0789	Transcriptional regulator
B8O09_RS19405	COG3040	lipid binding
B8O09_RS19415	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B8O09_RS19420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B8O09_RS19425	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B8O09_RS19430	COG1538	Outer membrane efflux protein
B8O09_RS19440	COG0745	RESPONSE REGULATOR receiver
B8O09_RS19445	COG5002	protein histidine kinase activity
B8O09_RS19460	COG2850	peptidyl-arginine hydroxylation
B8O09_RS19490	COG0842	Transport permease protein
B8O09_RS19495	COG1129	ABC transporter
B8O09_RS19495	COG0842	Transport permease protein
B8O09_RS19500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B8O09_RS19510	COG1879	ABC-type sugar transport system periplasmic component
B8O09_RS19515	COG1129	ABC transporter
B8O09_RS19520	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS19530	COG2249	NAD(P)H dehydrogenase (quinone) activity
B8O09_RS19545	COG0583	DNA-binding transcription factor activity
B8O09_RS19555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B8O09_RS19560	COG5457	Domain of unknown function (DUF1127)
B8O09_RS19570	COG1566	PFAM secretion protein HlyD family protein
B8O09_RS19585	COG1924	4 iron, 4 sulfur cluster binding
B8O09_RS19590	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
B8O09_RS19605	COG2733	membrane
B8O09_RS19615	COG2207	Transcriptional regulator
B8O09_RS19615	COG1917	Cupin 2, conserved barrel domain protein
B8O09_RS19625	COG5464	transposase or invertase
B8O09_RS19630	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS19640	COG0523	cobalamin synthesis protein
B8O09_RS19645	COG2879	small protein
B8O09_RS19650	COG1966	Carbon starvation protein
B8O09_RS19665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B8O09_RS19670	COG2368	4-hydroxyphenylacetate
B8O09_RS19690	COG3971	2-oxopent-4-enoate hydratase activity
B8O09_RS19700	COG3384	dioxygenase
B8O09_RS19705	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS19715	COG0179	Fumarylacetoacetate (FAA) hydrolase
B8O09_RS19725	COG1846	Transcriptional regulator
B8O09_RS19755	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B8O09_RS19765	COG4145	pantothenate transmembrane transporter activity
B8O09_RS19770	COG3734	2-keto-3-deoxy-galactonokinase
B8O09_RS19775	COG0800	Aldolase
B8O09_RS19780	COG1737	Transcriptional regulator
B8O09_RS19790	COG1214	PFAM Peptidase M22, glycoprotease
B8O09_RS19790	COG0456	acetyltransferase
B8O09_RS19795	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B8O09_RS19795	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B8O09_RS19810	COG3715	PTS system
B8O09_RS19815	COG3716	PTS system mannose fructose sorbose family IID component
B8O09_RS19820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B8O09_RS19830	COG5464	transposase or invertase
B8O09_RS19845	COG1484	DNA-dependent DNA replication
B8O09_RS19860	COG2966	Psort location CytoplasmicMembrane, score
B8O09_RS19880	COG2197	response regulator
B8O09_RS19885	COG2197	response regulator
B8O09_RS19890	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B8O09_RS19895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B8O09_RS19895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B8O09_RS19900	COG4114	ferric iron reductase
B8O09_RS19905	COG3706	GGDEF domain
B8O09_RS19935	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
B8O09_RS19940	COG0456	acetyltransferase
B8O09_RS19945	COG1011	Hydrolase
B8O09_RS19955	COG2823	Periplasmic or secreted lipoprotein
B8O09_RS19965	COG4667	esterase of the alpha-beta hydrolase superfamily
B8O09_RS19970	COG0084	hydrolase, TatD family'
B8O09_RS19975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B8O09_RS20005	COG3726	membrane protein affecting hemolysin expression
B8O09_RS20015	COG0560	Phosphoserine phosphatase
B8O09_RS20020	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B8O09_RS20030	COG0488	(ABC) transporter
B8O09_RS20040	COG0741	lytic transglycosylase activity
B8O09_RS20060	COG3708	Transcriptional regulator
B8O09_RS20060	COG2207	Transcriptional regulator
B8O09_RS20065	COG3045	CreA protein
B8O09_RS20070	COG0745	RESPONSE REGULATOR receiver
B8O09_RS20075	COG2205	protein histidine kinase activity
B8O09_RS20080	COG4452	Inner membrane protein CreD
B8O09_RS20085	COG0745	RESPONSE REGULATOR receiver
B8O09_RS20100	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
B8O09_RS20110	COG0527	aspartate kinase activity
B8O09_RS20110	COG0460	homoserine dehydrogenase
B8O09_RS20120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B8O09_RS20145	COG1115	amino acid carrier protein
B8O09_RS20150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B8O09_RS20155	COG0521	Mo-molybdopterin cofactor biosynthetic process
B8O09_RS20160	COG0477	Major facilitator Superfamily
B8O09_RS20165	COG1584	GPR1 FUN34 yaaH family protein
B8O09_RS20170	COG4735	regulation of single-species biofilm formation
B8O09_RS20195	COG0583	DNA-binding transcription factor activity
B8O09_RS20215	COG0196	riboflavin kinase activity
B8O09_RS20230	COG1047	Peptidyl-prolyl cis-trans
B8O09_RS20255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B8O09_RS20270	COG0505	Belongs to the CarA family
B8O09_RS20325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B8O09_RS20335	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B8O09_RS20340	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B8O09_RS20355	COG3493	citrate carrier protein
B8O09_RS20370	COG0564	pseudouridine synthase activity
B8O09_RS20380	COG0417	DNA replication proofreading
B8O09_RS20385	COG0235	Class ii aldolase
B8O09_RS20405	COG0586	Pfam SNARE associated Golgi protein
B8O09_RS20415	COG1178	ABC-type Fe3 transport system permease component
B8O09_RS20435	COG2814	Major facilitator Superfamily
B8O09_RS20440	COG2271	Major facilitator Superfamily
B8O09_RS20445	COG0583	DNA-binding transcription factor activity
B8O09_RS20455	COG0738	Major facilitator superfamily
B8O09_RS20505	COG0028	Belongs to the TPP enzyme family
B8O09_RS20515	COG1609	Transcriptional regulator
B8O09_RS20540	COG0768	penicillin binding
B8O09_RS20545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B8O09_RS20550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B8O09_RS20565	COG0772	Belongs to the SEDS family
B8O09_RS20590	COG0849	cell division
B8O09_RS20595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B8O09_RS20615	COG0494	nUDIX hydrolase
B8O09_RS20640	COG1459	type II secretion system
B8O09_RS20645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B8O09_RS20650	COG4969	Belongs to the N-Me-Phe pilin family
B8O09_RS20660	COG3023	N-Acetylmuramoyl-L-alanine amidase
B8O09_RS20665	COG3725	Membrane protein required for beta-lactamase induction
B8O09_RS20670	COG3940	Belongs to the glycosyl hydrolase 43 family
B8O09_RS20675	COG2211	Major facilitator Superfamily
B8O09_RS20680	COG1113	amino acid transport
B8O09_RS20685	COG2186	Transcriptional regulator
B8O09_RS20690	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B8O09_RS20695	COG0508	dehydrogenase complex catalyzes the overall conversion of
B8O09_RS20700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B8O09_RS20715	COG3064	Membrane
B8O09_RS20755	COG2132	Multicopper oxidase
B8O09_RS20760	COG4993	Dehydrogenase
B8O09_RS20770	COG0288	reversible hydration of carbon dioxide
B8O09_RS20775	COG1131	(ABC) transporter
B8O09_RS20780	COG0842	Transport permease protein
B8O09_RS20785	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS20790	COG0726	polysaccharide deacetylase
B8O09_RS20810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B8O09_RS20815	COG0617	tRNA 3'-terminal CCA addition
B8O09_RS20835	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B8O09_RS20840	COG1643	Atp-dependent helicase
B8O09_RS20930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B8O09_RS20940	COG1120	ATPase activity
B8O09_RS20945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B8O09_RS20950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B8O09_RS20970	COG2860	membrane
B8O09_RS20990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B8O09_RS20995	COG3835	regulator
B8O09_RS21010	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B8O09_RS21015	COG0024	Methionine aminopeptidase
B8O09_RS21040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B8O09_RS21055	COG0575	Belongs to the CDS family
B8O09_RS21060	COG0750	zinc metalloprotease
B8O09_RS21070	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
B8O09_RS21100	COG0587	DNA-directed DNA polymerase activity
B8O09_RS21110	COG1982	Orn Lys Arg decarboxylase major
B8O09_RS21115	COG0346	lactoylglutathione lyase activity
B8O09_RS21125	COG4568	rho-dependent transcription termination
B8O09_RS21140	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B8O09_RS21145	COG3015	lipoprotein NlpE involved in copper resistance
B8O09_RS21150	COG0791	NLP P60 protein
B8O09_RS21160	COG1720	tRNA m6t6A37 methyltransferase activity
B8O09_RS21170	COG1464	Belongs to the NlpA lipoprotein family
B8O09_RS21175	COG2011	ABC-type metal ion transport system permease component
B8O09_RS21185	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B8O09_RS21220	COG0656	L-ascorbic acid biosynthetic process
B8O09_RS21225	COG0583	DNA-binding transcription factor activity
B8O09_RS21230	COG2814	Major facilitator Superfamily
B8O09_RS21240	COG2226	methyltransferase
B8O09_RS21245	COG1388	LysM domain
B8O09_RS21245	COG0741	lytic transglycosylase activity
B8O09_RS21255	COG2226	methyltransferase
B8O09_RS21265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B8O09_RS21275	COG0583	DNA-binding transcription factor activity
B8O09_RS21285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B8O09_RS21290	COG1960	acyl-CoA dehydrogenase activity
B8O09_RS21300	COG0121	glutamine amidotransferase
B8O09_RS21305	COG3034	peptidoglycan biosynthetic process
B8O09_RS21325	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B8O09_RS21330	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B8O09_RS21345	COG2991	Protein conserved in bacteria
B8O09_RS21360	COG0454	-acetyltransferase
B8O09_RS21365	COG2195	Cleaves the N-terminal amino acid of tripeptides
B8O09_RS21385	COG1802	Transcriptional regulator
B8O09_RS21390	COG1113	amino acid transport
B8O09_RS21395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B8O09_RS21400	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS21405	COG0579	oxidoreductase
B8O09_RS21425	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B8O09_RS21430	COG0625	glutathione transferase activity
B8O09_RS21440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B8O09_RS21450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B8O09_RS21455	COG0508	dehydrogenase complex catalyzes the overall conversion of
B8O09_RS21460	COG0022	dehydrogenase e1 component
B8O09_RS21465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B8O09_RS21485	COG0745	RESPONSE REGULATOR receiver
B8O09_RS21500	COG3188	usher protein
B8O09_RS21505	COG3121	Chaperone
B8O09_RS21540	COG0582	viral genome integration into host DNA
B8O09_RS21565	COG0791	NLP P60 protein
B8O09_RS21595	COG3639	organic phosphonate transmembrane transporter activity
B8O09_RS21605	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
B8O09_RS21630	COG3188	usher protein
B8O09_RS21645	COG0765	amino acid transport
B8O09_RS21650	COG4597	amino acid ABC transporter
B8O09_RS21660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B8O09_RS21695	COG4302	ethanolamine ammonia-lyase activity
B8O09_RS21700	COG4303	Ethanolamine ammonia lyase large subunit
B8O09_RS21710	COG0833	amino acid
B8O09_RS21715	COG2040	homocysteine
B8O09_RS21720	COG4521	taurine ABC transporter
B8O09_RS21725	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B8O09_RS21730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B8O09_RS21735	COG2175	clavaminate synthase activity
B8O09_RS21745	COG0113	porphobilinogen synthase activity
B8O09_RS21750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B8O09_RS21755	COG1335	isochorismatase
B8O09_RS21760	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
B8O09_RS21800	COG1785	Belongs to the alkaline phosphatase family
B8O09_RS21810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B8O09_RS21820	COG3416	Protein conserved in bacteria
B8O09_RS21825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B8O09_RS21835	COG4126	flavin adenine dinucleotide binding
B8O09_RS21850	COG1940	carbohydrate kinase activity
B8O09_RS21855	COG0419	ATPase involved in DNA repair
B8O09_RS21860	COG0420	3'-5' exonuclease activity
B8O09_RS21885	COG0366	Alpha amylase catalytic
B8O09_RS21890	COG0583	DNA-binding transcription factor activity
B8O09_RS21895	COG1335	isochorismatase
B8O09_RS21905	COG1228	amidohydrolase
B8O09_RS21915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B8O09_RS21930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B8O09_RS21935	COG0450	alkyl hydroperoxide reductase
B8O09_RS21955	COG1862	Preprotein translocase
B8O09_RS21960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B8O09_RS21965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B8O09_RS21985	COG4238	major outer membrane lipoprotein
B8O09_RS21995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B8O09_RS21995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B8O09_RS22015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B8O09_RS22020	COG0667	Aldo Keto reductase
B8O09_RS22030	COG0142	geranyltranstransferase activity
B8O09_RS22050	COG0693	protein deglycase activity
B8O09_RS22055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B8O09_RS22065	COG2814	Major facilitator Superfamily
B8O09_RS22070	COG0673	inositol 2-dehydrogenase activity
B8O09_RS22085	COG1053	succinate dehydrogenase
B8O09_RS22095	COG1053	succinate dehydrogenase
B8O09_RS22100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B8O09_RS22105	COG1414	Transcriptional regulator
B8O09_RS22120	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B8O09_RS22125	COG1845	cytochrome c oxidase, subunit III
B8O09_RS22130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B8O09_RS22135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B8O09_RS22140	COG2223	nitrite transmembrane transporter activity
B8O09_RS22145	COG3056	Lipoprotein
B8O09_RS22150	COG0271	Belongs to the BolA IbaG family
B8O09_RS22180	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B8O09_RS22185	COG0776	regulation of translation
B8O09_RS22190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B8O09_RS22195	COG1555	photosystem II stabilization
B8O09_RS22200	COG0824	Thioesterase
B8O09_RS22210	COG4533	DNA binding
B8O09_RS22225	COG1522	sequence-specific DNA binding
B8O09_RS22230	COG1132	(ABC) transporter
B8O09_RS22235	COG1132	(ABC) transporter
B8O09_RS22240	COG0347	Belongs to the P(II) protein family
B8O09_RS22245	COG0004	ammonium transporteR
B8O09_RS22250	COG1946	Acyl-CoA thioesterase
B8O09_RS22255	COG3126	Type III secretion system lipoprotein chaperone (YscW)
B8O09_RS22260	COG3695	enzyme binding
B8O09_RS22330	COG2364	Membrane
B8O09_RS22355	COG2182	Extracellular solute-binding protein
B8O09_RS22360	COG1175	transmembrane transport
B8O09_RS22365	COG3833	ABC-type maltose transport systems, permease component
B8O09_RS22370	COG3867	Arabinogalactan endo-beta-1,4-galactanase
B8O09_RS22375	COG1874	Beta-galactosidase
B8O09_RS22420	COG0110	maltose O-acetyltransferase activity
B8O09_RS22435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B8O09_RS22440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B8O09_RS22445	COG1309	transcriptional regulator
B8O09_RS22450	COG3264	Mechanosensitive ion channel
B8O09_RS22450	COG1196	nuclear chromosome segregation
B8O09_RS22455	COG5464	transposase or invertase
B8O09_RS22465	COG3923	Primosomal replication protein n
B8O09_RS22470	COG2832	Protein of unknown function (DUF454)
B8O09_RS22510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B8O09_RS22515	COG4651	solute:proton antiporter activity
B8O09_RS22515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B8O09_RS22520	COG2223	nitrite transmembrane transporter activity
B8O09_RS22530	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B8O09_RS22535	COG3735	TraB family
B8O09_RS22550	COG1585	Membrane protein implicated in regulation of membrane protease activity
B8O09_RS22555	COG0330	HflC and HflK could
B8O09_RS22560	COG4619	ABC transporter
B8O09_RS22565	COG0390	transport system, permease component
B8O09_RS22575	COG3118	belongs to the thioredoxin family
B8O09_RS22580	COG0300	oxidoreductase activity
B8O09_RS22585	COG2755	lipolytic protein G-D-S-L family
B8O09_RS22590	COG4181	ATPase activity
B8O09_RS22595	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B8O09_RS22610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B8O09_RS22615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B8O09_RS22635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B8O09_RS22645	COG2501	S4 domain
B8O09_RS22665	COG0582	viral genome integration into host DNA
B8O09_RS22745	COG0305	Participates in initiation and elongation during chromosome replication
B8O09_RS22830	COG3772	lysozyme
B8O09_RS22870	COG1783	phage Terminase large subunit
B8O09_RS22875	COG3567	Phage-associated protein, HI1409 family
B8O09_RS22945	COG0741	lytic transglycosylase activity
B8O09_RS22995	COG5301	cellulose 1,4-beta-cellobiosidase activity
B8O09_RS23000	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B8O09_RS23015	COG0582	viral genome integration into host DNA
B8O09_RS23050	COG3539	Fimbrial protein
B8O09_RS23055	COG3121	Chaperone
B8O09_RS23060	COG3188	usher protein
B8O09_RS23075	COG1560	Kdo2-lipid A biosynthetic process
B8O09_RS23085	COG3710	Transcriptional regulator
B8O09_RS23090	COG0531	amino acid
B8O09_RS23095	COG1982	Orn Lys Arg decarboxylase major
B8O09_RS23100	COG3104	oligopeptide transport
B8O09_RS23130	COG0673	inositol 2-dehydrogenase activity
B8O09_RS23145	COG1129	ABC transporter
B8O09_RS23150	COG4211	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS23195	COG1566	PFAM secretion protein HlyD family protein
B8O09_RS23200	COG1120	ATPase activity
B8O09_RS23205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B8O09_RS23230	COG1473	amidohydrolase
B8O09_RS23235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B8O09_RS23240	COG0667	Aldo Keto reductase
B8O09_RS23305	COG3775	system Galactitol-specific IIC component
B8O09_RS23310	COG1070	Carbohydrate kinase
B8O09_RS23315	COG1063	alcohol dehydrogenase
B8O09_RS23320	COG2188	Transcriptional regulator
B8O09_RS23340	COG1063	alcohol dehydrogenase
B8O09_RS23365	COG0531	amino acid
B8O09_RS23375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B8O09_RS23380	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS23395	COG1113	amino acid transport
B8O09_RS23400	COG2211	Major facilitator Superfamily
B8O09_RS23410	COG0673	inositol 2-dehydrogenase activity
B8O09_RS23420	COG2771	luxR family
B8O09_RS23435	COG3188	usher protein
B8O09_RS23460	COG1609	Transcriptional regulator
B8O09_RS23465	COG0668	transmembrane transport
B8O09_RS23470	COG0477	Major facilitator Superfamily
B8O09_RS23505	COG2315	Protein conserved in bacteria
B8O09_RS23550	COG3698	Phosphodiester glycosidase
B8O09_RS23560	COG0697	spore germination
B8O09_RS23575	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
B8O09_RS23580	COG0765	amino acid transport
B8O09_RS23585	COG4215	(ABC) transporter
B8O09_RS23595	COG4221	oxidoreductase activity
B8O09_RS23600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B8O09_RS23615	COG4608	Belongs to the ABC transporter superfamily
B8O09_RS23620	COG0444	Belongs to the ABC transporter superfamily
B8O09_RS23625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B8O09_RS23630	COG0601	transmembrane transport
B8O09_RS23635	COG0747	negative chemotaxis
B8O09_RS23665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B8O09_RS23675	COG0668	transmembrane transport
B8O09_RS23680	COG0583	DNA-binding transcription factor activity
B8O09_RS23690	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS23700	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS23705	COG1129	ABC transporter
B8O09_RS23715	COG1879	ABC-type sugar transport system periplasmic component
B8O09_RS23720	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B8O09_RS23725	COG2390	Transcriptional regulator
B8O09_RS23735	COG3959	Transketolase, thiamine diphosphate binding domain
B8O09_RS23740	COG3958	Transketolase
B8O09_RS23745	COG2977	Belongs to the P-Pant transferase superfamily
B8O09_RS23750	COG4771	TonB-dependent receptor
B8O09_RS23760	COG2382	esterase
B8O09_RS23765	COG3251	PFAM MbtH domain protein
B8O09_RS23770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B8O09_RS23770	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B8O09_RS23775	COG1120	ATPase activity
B8O09_RS23780	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B8O09_RS23785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B8O09_RS23795	COG4592	Periplasmic binding protein
B8O09_RS23800	COG1169	isochorismate synthase
B8O09_RS23805	COG1021	2,3-dihydroxybenzoate-AMP ligase
B8O09_RS23810	COG1535	isochorismatase
B8O09_RS23810	COG3433	isochorismatase activity
B8O09_RS23815	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS23825	COG1966	Carbon starvation protein
B8O09_RS23830	COG2879	small protein
B8O09_RS23835	COG2211	Major facilitator Superfamily
B8O09_RS23850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B8O09_RS23860	COG2188	Transcriptional regulator
B8O09_RS23865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B8O09_RS23890	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS23895	COG0371	Dehydrogenase
B8O09_RS23900	COG1129	ABC transporter
B8O09_RS23905	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS23935	COG2271	Major facilitator Superfamily
B8O09_RS23940	COG0483	inositol monophosphate 1-phosphatase activity
B8O09_RS23950	COG0402	S-adenosylhomocysteine deaminase activity
B8O09_RS23960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B8O09_RS23975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B8O09_RS23985	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS23990	COG1172	Belongs to the binding-protein-dependent transport system permease family
B8O09_RS23995	COG1129	ABC transporter
B8O09_RS24020	COG0436	Aminotransferase
B8O09_RS24025	COG1475	DNA binding
B8O09_RS24030	COG3969	phosphoadenosine phosphosulfate
B8O09_RS24035	COG0583	DNA-binding transcription factor activity
B8O09_RS24040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B8O09_RS24060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B8O09_RS24065	COG3719	Belongs to the RNase T2 family
B8O09_RS24070	COG3069	C4-dicarboxylate transmembrane transporter activity
B8O09_RS24090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B8O09_RS24105	COG0583	DNA-binding transcription factor activity
B8O09_RS24120	COG1686	Belongs to the peptidase S11 family
B8O09_RS24125	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B8O09_RS24130	COG0772	Belongs to the SEDS family
B8O09_RS24135	COG0768	penicillin binding
B8O09_RS24145	COG0799	negative regulation of ribosome biogenesis
B8O09_RS24165	COG1466	dna polymerase III delta subunit
B8O09_RS24180	COG2888	peptidyl-tyrosine sulfation
B8O09_RS24195	COG1126	abc transporter atp-binding protein
B8O09_RS24200	COG0765	amino acid transport
B8O09_RS24205	COG0765	amino acid transport
B8O09_RS24230	COG1702	phosphate starvation-inducible protein PhoH
B8O09_RS24240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B8O09_RS24285	COG0367	asparagine synthase
B8O09_RS24290	COG0647	UMP catabolic process
B8O09_RS24295	COG1846	Transcriptional regulator
B8O09_RS24295	COG1940	carbohydrate kinase activity
B8O09_RS24300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B8O09_RS24345	COG0735	belongs to the Fur family
B8O09_RS24360	COG0596	Alpha beta hydrolase
B8O09_RS24370	COG0033	Phosphoglucomutase
B8O09_RS24380	COG0745	RESPONSE REGULATOR receiver
B8O09_RS24385	COG2205	protein histidine kinase activity
B8O09_RS24415	COG0415	Belongs to the DNA photolyase family
B8O09_RS24430	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B8O09_RS24435	COG1984	allophanate hydrolase subunit 2
B8O09_RS24475	COG2009	succinate dehydrogenase
B8O09_RS24480	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B8O09_RS24485	COG1053	succinate dehydrogenase
B8O09_RS24490	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B8O09_RS24495	COG0567	Dehydrogenase, E1 component
B8O09_RS24500	COG0508	dehydrogenase complex catalyzes the overall conversion of
B8O09_RS24510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B8O09_RS24520	COG1271	oxidase subunit
B8O09_RS24525	COG1294	oxidase, subunit
B8O09_RS24530	COG4890	Cyd operon protein YbgT
B8O09_RS24535	COG3790	cyd operon protein YbgE
B8O09_RS24540	COG0824	Thioesterase
B8O09_RS24545	COG0811	peptide transport
B8O09_RS24550	COG0848	biopolymer transport protein
B8O09_RS24555	COG3064	Membrane
B8O09_RS24565	COG2885	chlorophyll binding
B8O09_RS24570	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
B8O09_RS24615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B8O09_RS24620	COG3201	nicotinamide mononucleotide transporter
B8O09_RS24635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B8O09_RS24645	COG2017	converts alpha-aldose to the beta-anomer
B8O09_RS24655	COG1085	galactose-1-phosphate uridylyltransferase
B8O09_RS24665	COG1119	ATPase activity
B8O09_RS24670	COG3585	molybdate ion transport
B8O09_RS24670	COG2005	Transcriptional regulator
B8O09_RS24680	COG0725	ABC transporter, periplasmic molybdate-binding protein
B8O09_RS24685	COG4149	molybdate abc transporter
B8O09_RS24695	COG0561	phosphatase activity
B8O09_RS24720	COG2200	EAL domain
B8O09_RS24725	COG0789	Transcriptional regulator
B8O09_RS24760	COG4677	pectinesterase activity
B8O09_RS24795	COG1881	PFAM PEBP family protein
B8O09_RS24800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B8O09_RS24815	COG2226	methyltransferase
B8O09_RS24850	COG0642	Histidine kinase
B8O09_RS24855	COG0745	RESPONSE REGULATOR receiver
B8O09_RS24880	COG0521	Mo-molybdopterin cofactor biosynthetic process
B8O09_RS24890	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B8O09_RS24895	COG0314	molybdopterin synthase activity
B8O09_RS24900	COG0670	Belongs to the BI1 family
B8O09_RS24905	COG0392	lysyltransferase activity
B8O09_RS24910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B8O09_RS24925	COG0842	Transport permease protein
B8O09_RS24930	COG0842	Transport permease protein
B8O09_RS24935	COG1131	(ABC) transporter
B8O09_RS24940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B8O09_RS24945	COG1309	transcriptional regulator
B8O09_RS24950	COG0583	DNA-binding transcription factor activity
B8O09_RS24955	COG2271	Major facilitator Superfamily
B8O09_RS24960	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS24965	COG3959	Transketolase, thiamine diphosphate binding domain
B8O09_RS24970	COG3958	Transketolase
B8O09_RS24975	COG0513	Belongs to the DEAD box helicase family
B8O09_RS24980	COG1199	ATP-dependent helicase activity
B8O09_RS24985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B8O09_RS24995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B8O09_RS25005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B8O09_RS25015	COG0668	transmembrane transport
B8O09_RS25020	COG1126	abc transporter atp-binding protein
B8O09_RS25025	COG0765	amino acid transport
B8O09_RS25030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B8O09_RS25045	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B8O09_RS25050	COG2194	sulfuric ester hydrolase activity
B8O09_RS25065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B8O09_RS25070	COG2723	6-phospho-beta-galactosidase activity
B8O09_RS25075	COG2188	Transcriptional regulator
B8O09_RS25080	COG1376	ErfK ybiS ycfS ynhG family protein
B8O09_RS25085	COG2365	Tyrosine phosphatase family
B8O09_RS25090	COG0488	(ABC) transporter
B8O09_RS25100	COG2271	Major facilitator Superfamily
B8O09_RS25105	COG1609	Transcriptional regulator
B8O09_RS25115	COG0561	phosphatase activity
B8O09_RS25120	COG1882	Formate acetyltransferase
B8O09_RS25125	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B8O09_RS25130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B8O09_RS25135	COG0303	'Molybdopterin
B8O09_RS25150	COG0747	negative chemotaxis
B8O09_RS25170	COG2223	nitrite transmembrane transporter activity
B8O09_RS25180	COG2133	pyrroloquinoline quinone binding
B8O09_RS25185	COG0625	glutathione transferase activity
B8O09_RS25190	COG1686	Belongs to the peptidase S11 family
B8O09_RS25195	COG1349	DNA-binding transcription factor activity
B8O09_RS25200	COG0671	phosphoesterase, PA-phosphatase related
B8O09_RS25210	COG2814	Major facilitator Superfamily
B8O09_RS25215	COG0561	phosphatase activity
B8O09_RS25220	COG0738	Major facilitator superfamily
B8O09_RS25225	COG3226	Transcriptional regulator
B8O09_RS25250	COG0778	Nitroreductase
B8O09_RS25265	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B8O09_RS25270	COG3842	ATPase activity
B8O09_RS25275	COG1176	ABC-type spermidine putrescine transport system, permease component I
B8O09_RS25280	COG1177	transmembrane transport
B8O09_RS25295	COG0745	RESPONSE REGULATOR receiver
B8O09_RS25300	COG5002	protein histidine kinase activity
B8O09_RS25305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B8O09_RS25310	COG4160	amino acid transport
B8O09_RS25315	COG4215	(ABC) transporter
B8O09_RS25320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B8O09_RS25325	COG1126	abc transporter atp-binding protein
B8O09_RS25340	COG3706	GGDEF domain
B8O09_RS25340	COG4251	negative regulation of phosphorylation
B8O09_RS25340	COG5001	Diguanylate cyclase
B8O09_RS25340	COG2203	Gaf domain
B8O09_RS25345	COG3023	N-Acetylmuramoyl-L-alanine amidase
B8O09_RS25350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B8O09_RS25355	COG0702	epimerase
B8O09_RS25360	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
B8O09_RS25365	COG0028	Belongs to the TPP enzyme family
B8O09_RS25375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B8O09_RS25385	COG2431	L-lysine efflux transmembrane transporter activity
B8O09_RS25395	COG3593	DNA synthesis involved in DNA repair
B8O09_RS25400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B8O09_RS25415	COG1278	Cold shock
B8O09_RS25425	COG0542	response to heat
B8O09_RS25440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B8O09_RS25445	COG4988	ABC transporter
B8O09_RS25450	COG0492	ferredoxin-NADP+ reductase activity
B8O09_RS25465	COG1178	ABC-type Fe3 transport system permease component
B8O09_RS25465	COG1674	ftsk spoiiie
B8O09_RS25475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B8O09_RS25485	COG0243	molybdopterin cofactor binding
B8O09_RS25490	COG0437	4 iron, 4 sulfur cluster binding
B8O09_RS25495	COG3302	dmso reductase anchor subunit
B8O09_RS25505	COG0477	Major facilitator Superfamily
B8O09_RS25510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B8O09_RS25515	COG1882	Formate acetyltransferase
B8O09_RS25520	COG2116	formate transmembrane transporter activity
B8O09_RS25525	COG1944	ATP diphosphatase activity
B8O09_RS25530	COG2323	membrane
B8O09_RS25550	COG0539	negative regulation of cytoplasmic translation
B8O09_RS25560	COG0658	competence protein
B8O09_RS25560	COG2333	competence protein COMEC
B8O09_RS25575	COG3214	Protein conserved in bacteria
B8O09_RS25590	COG3173	Aminoglycoside phosphotransferase
B8O09_RS25595	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B8O09_RS25600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B8O09_RS25610	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
B8O09_RS25620	COG2989	Protein conserved in bacteria
B8O09_RS25630	COG3108	Peptidase M15
B8O09_RS25635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B8O09_RS25640	COG1448	Aminotransferase
B8O09_RS25645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
B8O09_RS25650	COG3344	reverse transcriptase
B8O09_RS25675	COG1522	sequence-specific DNA binding
B8O09_RS25685	COG0814	amino acid
B8O09_RS25695	COG1473	amidohydrolase
B8O09_RS25705	COG0308	aminopeptidase N
B8O09_RS25715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B8O09_RS25720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B8O09_RS25725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B8O09_RS25730	COG0431	NADPH-dependent FMN reductase
B8O09_RS25745	COG0633	Ferredoxin
B8O09_RS25745	COG3217	Mosc domain protein beta barrel domain protein
B8O09_RS25755	COG0488	(ABC) transporter
B8O09_RS25760	COG2995	paraquat-inducible protein a
B8O09_RS25765	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B8O09_RS25765	COG3008	intermembrane lipid transfer
B8O09_RS25770	COG3009	Protein conserved in bacteria
B8O09_RS25780	COG3130	regulation of translation
B8O09_RS25790	COG1067	ATP-dependent peptidase activity
B8O09_RS25815	COG3070	regulator of competence-specific genes
B8O09_RS25820	COG1289	transmembrane transporter activity
B8O09_RS25825	COG3304	Inner membrane component domain
B8O09_RS25830	COG0210	DNA helicase
B8O09_RS25840	COG1832	CoA-binding protein
B8O09_RS25855	COG1881	PFAM PEBP family protein
B8O09_RS25860	COG2207	Transcriptional regulator
B8O09_RS25875	COG0670	Belongs to the BI1 family
B8O09_RS25930	COG1396	sequence-specific DNA binding
B8O09_RS26135	COG3772	lysozyme
B8O09_RS26175	COG2200	EAL domain
B8O09_RS26180	COG2200	EAL domain
B8O09_RS26190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B8O09_RS26195	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS26200	COG4638	Rieske (2fe-2S)
B8O09_RS26205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B8O09_RS26210	COG0473	3-isopropylmalate dehydrogenase activity
B8O09_RS26215	COG0583	DNA-binding transcription factor activity
B8O09_RS26220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B8O09_RS26225	COG1012	belongs to the aldehyde dehydrogenase family
B8O09_RS26230	COG1396	sequence-specific DNA binding
B8O09_RS26230	COG1917	Cupin 2, conserved barrel domain protein
B8O09_RS26235	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B8O09_RS26240	COG0174	glutamine synthetase
B8O09_RS26250	COG0531	amino acid
B8O09_RS26265	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS26290	COG3729	General stress protein
B8O09_RS26300	COG2233	PERMEase
B8O09_RS26335	COG1309	transcriptional regulator
B8O09_RS26350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B8O09_RS26360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B8O09_RS26380	COG1702	phosphate starvation-inducible protein PhoH
B8O09_RS26395	COG1335	isochorismatase
B8O09_RS26405	COG0583	DNA-binding transcription factor activity
B8O09_RS26410	COG1309	transcriptional regulator
B8O09_RS26455	COG3381	protein complex oligomerization
B8O09_RS26495	COG5645	(Lipo)protein
B8O09_RS26515	COG1560	Kdo2-lipid A biosynthetic process
B8O09_RS26565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B8O09_RS26585	COG2814	Major facilitator Superfamily
B8O09_RS26590	COG0583	DNA-binding transcription factor activity
B8O09_RS26595	COG1530	ribonuclease E activity
B8O09_RS26610	COG1399	metal-binding, possibly nucleic acid-binding protein
B8O09_RS26630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B8O09_RS26645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B8O09_RS26650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B8O09_RS26655	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B8O09_RS26665	COG0470	DNA polymerase III
B8O09_RS26670	COG0084	hydrolase, TatD family'
B8O09_RS26680	COG0537	adenosine 5'-monophosphoramidase activity
B8O09_RS26685	COG5633	Lipoprotein
B8O09_RS26715	COG1252	NADH dehydrogenase
B8O09_RS26720	COG3134	Outer membrane lipoprotein
B8O09_RS26730	COG1309	transcriptional regulator
B8O09_RS26740	COG1376	ErfK ybiS ycfS ynhG family protein
B8O09_RS26740	COG1388	LysM domain
B8O09_RS26745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B8O09_RS26750	COG4591	ABC-type transport system involved in lipoprotein release permease component
B8O09_RS26760	COG4591	ABC-type transport system involved in lipoprotein release permease component
B8O09_RS26770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B8O09_RS26780	COG2390	Transcriptional regulator
B8O09_RS26795	COG3395	kinase activity
B8O09_RS26810	COG0698	ribose 5-phosphate isomerase
B8O09_RS26815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B8O09_RS26820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B8O09_RS26825	COG0318	PFAM AMP-dependent synthetase and ligase
B8O09_RS26840	COG1177	transmembrane transport
B8O09_RS26860	COG1943	Transposase
B8O09_RS26865	COG2850	peptidyl-arginine hydroxylation
B8O09_RS26870	COG2205	protein histidine kinase activity
B8O09_RS26890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B8O09_RS26910	COG1187	pseudouridine synthase activity
B8O09_RS26915	COG0538	isocitrate dehydrogenase activity
B8O09_RS26920	COG0640	Transcriptional regulator
B8O09_RS26940	COG3813	Protein conserved in bacteria
B8O09_RS26945	COG1063	alcohol dehydrogenase
B8O09_RS26950	COG3729	General stress protein
B8O09_RS26955	COG3685	Protein conserved in bacteria
B8O09_RS26960	COG3685	Protein conserved in bacteria
B8O09_RS26965	COG3546	catalase activity
B8O09_RS26970	COG1271	oxidase subunit
B8O09_RS26975	COG1294	oxidase, subunit
B8O09_RS26995	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B8O09_RS27000	COG0583	DNA-binding transcription factor activity
B8O09_RS27005	COG3706	GGDEF domain
B8O09_RS27010	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B8O09_RS27025	COG0426	domain, Protein
B8O09_RS27025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B8O09_RS27050	COG2026	Addiction module toxin, RelE StbE family
B8O09_RS27055	COG3077	Addiction module antitoxin, RelB DinJ family
B8O09_RS27065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B8O09_RS27080	COG3547	Transposase (IS116 IS110 IS902 family)
B8O09_RS27085	COG2801	Transposase and inactivated derivatives
B8O09_RS27095	COG1560	Kdo2-lipid A biosynthetic process
B8O09_RS27105	COG3182	Iron-regulated membrane protein
B8O09_RS27125	COG2199	diguanylate cyclase activity
B8O09_RS27125	COG2203	Gaf domain
B8O09_RS27130	COG3042	response to heat
B8O09_RS27135	COG3189	MarR family transcriptional regulator
B8O09_RS27140	COG1683	Conserved Protein
B8O09_RS27145	COG0504	CTP synthase activity
B8O09_RS27150	COG2807	transmembrane transport
B8O09_RS27155	COG2207	Transcriptional regulator
B8O09_RS27165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B8O09_RS27170	COG0859	PFAM glycosyl transferase family 9
B8O09_RS27180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B8O09_RS27185	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B8O09_RS27190	COG0583	DNA-binding transcription factor activity
B8O09_RS27195	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS27215	COG0386	Belongs to the glutathione peroxidase family
B8O09_RS27230	COG2766	serine protein kinase
B8O09_RS27235	COG3713	MltA-interacting MipA family protein
B8O09_RS27240	COG0656	L-ascorbic acid biosynthetic process
B8O09_RS27260	COG3139	Protein of unknown function (DUF1315)
B8O09_RS27275	COG1335	isochorismatase
B8O09_RS27280	COG0252	asparaginase activity
B8O09_RS27285	COG0616	signal peptide processing
B8O09_RS27290	COG0778	Nitroreductase
B8O09_RS27310	COG0709	Synthesizes selenophosphate from selenide and ATP
B8O09_RS27315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B8O09_RS27320	COG0604	alcohol dehydrogenase
B8O09_RS27320	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS27320	COG3321	synthase
B8O09_RS27325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B8O09_RS27330	COG0494	nUDIX hydrolase
B8O09_RS27335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B8O09_RS27340	COG2897	thiosulfate sulfurtransferase activity
B8O09_RS27345	COG4136	ATPase activity
B8O09_RS27350	COG4135	transport system, permease component
B8O09_RS27355	COG4134	Bacterial extracellular solute-binding protein
B8O09_RS27360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B8O09_RS27365	COG0398	Pfam SNARE associated Golgi protein
B8O09_RS27370	COG0398	Pfam SNARE associated Golgi protein
B8O09_RS27375	COG0708	Exodeoxyribonuclease III
B8O09_RS27385	COG3138	arginine N-succinyltransferase
B8O09_RS27515	COG0482	sulfurtransferase activity
B8O09_RS27530	COG0488	(ABC) transporter
B8O09_RS27535	COG3173	Aminoglycoside phosphotransferase
B8O09_RS27615	COG1192	Involved in chromosome partitioning
B8O09_RS27695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B8O09_RS27810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B8O09_RS27835	COG5001	Diguanylate cyclase
B8O09_RS27870	COG0714	Associated with various cellular activities
B8O09_RS27880	COG0629	single-stranded DNA binding
B8O09_RS27925	COG0633	Ferredoxin
B8O09_RS28120	COG3724	N-succinylarginine dihydrolase activity
B8O09_RS28130	COG3678	ATP-independent chaperone mediated protein folding
B8O09_RS28135	COG0322	excinuclease ABC activity
B8O09_RS28145	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B8O09_RS28150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B8O09_RS28155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B8O09_RS28160	COG1447	Phosphotransferase system cellobiose-specific component IIA
B8O09_RS28165	COG2169	Transcriptional regulator
B8O09_RS28165	COG1917	Cupin 2, conserved barrel domain protein
B8O09_RS28170	COG1486	melibiose metabolic process
B8O09_RS28180	COG0753	catalase activity
B8O09_RS28190	COG1823	symporter activity
B8O09_RS28195	COG1988	membrane-bound metal-dependent
B8O09_RS28200	COG1028	Short-chain dehydrogenase reductase Sdr
B8O09_RS28205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B8O09_RS28235	COG0727	PFAM Uncharacterised protein family (UPF0153)
B8O09_RS28240	COG3047	cAMP biosynthetic process
B8O09_RS28250	COG4774	siderophore transport
B8O09_RS28285	COG0134	indole-3-glycerol-phosphate synthase activity
B8O09_RS28285	COG0135	phosphoribosylanthranilate isomerase activity
B8O09_RS28290	COG0512	Glutamine amidotransferase of anthranilate synthase
B8O09_RS28290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B8O09_RS28295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B8O09_RS28305	COG0009	L-threonylcarbamoyladenylate synthase
B8O09_RS28315	COG0583	DNA-binding transcription factor activity
B8O09_RS28375	COG3344	reverse transcriptase
B8O09_RS28440	COG2199	diguanylate cyclase activity
B8O09_RS28440	COG2203	Gaf domain
B8O09_RS28445	COG5001	Diguanylate cyclase
B8O09_RS28445	COG1716	ATPase activity
B8O09_RS28460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B8O09_RS28470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B8O09_RS28520	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B8O09_RS28550	COG0739	heme binding
B8O09_RS28560	COG2132	Multicopper oxidase
B8O09_RS28565	COG3667	copper resistance
B8O09_RS28570	COG2372	response to copper ion
B8O09_RS28575	COG1276	copper resistance
B8O09_RS28580	COG0745	RESPONSE REGULATOR receiver
B8O09_RS28585	COG2205	protein histidine kinase activity
B8O09_RS28605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B8O09_RS28620	COG0431	NADPH-dependent FMN reductase
B8O09_RS28650	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B8O09_RS28715	COG2801	Transposase and inactivated derivatives
B8O09_RS28725	COG2801	Transposase and inactivated derivatives
B8O09_RS28855	COG0625	glutathione transferase activity
B8O09_RS28860	COG0110	maltose O-acetyltransferase activity
B8O09_RS28885	COG3344	reverse transcriptase
B8O09_RS28910	COG3041	Addiction module toxin RelE StbE family
B8O09_RS28915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B8O09_RS28935	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B8O09_RS29000	COG3039	Transposase
B8O09_RS29255	COG5499	transcription regulator containing HTH domain
B8O09_RS29340	COG1475	DNA binding
B8O09_RS29420	COG3344	reverse transcriptase
B8O09_RS29600	COG5499	transcription regulator containing HTH domain
B8O09_RS29625	COG3039	Transposase
B8O09_RS29635	COG2963	transposase activity
B8O09_RS29665	COG1475	DNA binding
B8O09_RS29805	COG1192	Involved in chromosome partitioning
B8O09_RS30225	COG0583	DNA-binding transcription factor activity
B8O09_RS30335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B8O09_RS30615	COG0583	DNA-binding transcription factor activity