locus-tag	class	description
EQH49_RS00025	COG0542	response to heat
EQH49_RS00040	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EQH49_RS00045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EQH49_RS00055	COG0077	Prephenate dehydratase
EQH49_RS00055	COG1605	Chorismate mutase
EQH49_RS00065	COG1605	Chorismate mutase
EQH49_RS00065	COG0287	Prephenate dehydrogenase
EQH49_RS00070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EQH49_RS00080	COG2199	diguanylate cyclase activity
EQH49_RS00085	COG2885	chlorophyll binding
EQH49_RS00120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EQH49_RS00125	COG4137	Cytochrome C assembly protein
EQH49_RS00130	COG4536	flavin adenine dinucleotide binding
EQH49_RS00145	COG0497	DNA recombination
EQH49_RS00160	COG2867	negative regulation of translational initiation
EQH49_RS00175	COG0582	viral genome integration into host DNA
EQH49_RS00190	COG0515	serine threonine protein kinase
EQH49_RS00190	COG2815	serine threonine protein kinase
EQH49_RS00260	COG3708	Transcriptional regulator
EQH49_RS00260	COG2207	Transcriptional regulator
EQH49_RS00265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQH49_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQH49_RS00310	COG0235	Class ii aldolase
EQH49_RS00320	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS00355	COG3121	Chaperone
EQH49_RS00360	COG3539	Fimbrial protein
EQH49_RS00370	COG3284	Transcriptional regulator
EQH49_RS00375	COG0583	DNA-binding transcription factor activity
EQH49_RS00385	COG0640	Transcriptional regulator
EQH49_RS00390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQH49_RS00405	COG2916	Histone family protein nucleoid-structuring protein H-NS
EQH49_RS00430	COG4575	ribosome binding
EQH49_RS00435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQH49_RS00440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQH49_RS00445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EQH49_RS00455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQH49_RS00470	COG4176	ABC-type proline glycine betaine transport system permease component
EQH49_RS00480	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EQH49_RS00490	COG1846	Transcriptional regulator
EQH49_RS00495	COG1566	PFAM secretion protein HlyD family protein
EQH49_RS00500	COG2814	Major facilitator Superfamily
EQH49_RS00505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EQH49_RS00525	COG1238	metal cluster binding
EQH49_RS00530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQH49_RS00535	COG2823	Periplasmic or secreted lipoprotein
EQH49_RS00565	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EQH49_RS00590	COG1546	Belongs to the CinA family
EQH49_RS00600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQH49_RS00605	COG1121	(ABC) transporter
EQH49_RS00620	COG2951	lytic endotransglycosylase activity
EQH49_RS00625	COG3730	PTS system glucitol sorbitol-specific
EQH49_RS00630	COG3732	PTS system glucitol sorbitol-specific
EQH49_RS00640	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS00645	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS00650	COG1349	DNA-binding transcription factor activity
EQH49_RS00680	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EQH49_RS00685	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EQH49_RS00690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EQH49_RS00695	COG1609	Transcriptional regulator
EQH49_RS00700	COG1263	PTS System
EQH49_RS00700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQH49_RS00705	COG2723	6-phospho-beta-galactosidase activity
EQH49_RS00715	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EQH49_RS00725	COG3260	NADH ubiquinone oxidoreductase 20
EQH49_RS00730	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EQH49_RS00735	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EQH49_RS00735	COG3261	NADH dehydrogenase
EQH49_RS00740	COG0650	Formate hydrogenlyase subunit 4
EQH49_RS00745	COG0651	ATP synthesis coupled electron transport
EQH49_RS00750	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EQH49_RS00770	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EQH49_RS00775	COG0298	carbon dioxide binding
EQH49_RS00780	COG0409	Hydrogenase expression formation protein
EQH49_RS00785	COG0309	Hydrogenase expression formation protein (HypE)
EQH49_RS00795	COG2723	6-phospho-beta-galactosidase activity
EQH49_RS00805	COG4580	involved in the transport of maltose and maltodextrins
EQH49_RS00815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQH49_RS00820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQH49_RS00825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQH49_RS00830	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQH49_RS00835	COG1940	carbohydrate kinase activity
EQH49_RS00840	COG1609	Transcriptional regulator
EQH49_RS00845	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQH49_RS00850	COG1121	(ABC) transporter
EQH49_RS00855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQH49_RS00860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQH49_RS00875	COG0679	Auxin Efflux Carrier
EQH49_RS00895	COG3720	iron ion transport
EQH49_RS00900	COG4558	Periplasmic binding protein
EQH49_RS00905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQH49_RS00950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EQH49_RS00955	COG0163	prenyltransferase activity
EQH49_RS00980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EQH49_RS00985	COG1388	LysM domain
EQH49_RS00985	COG4942	peptidase
EQH49_RS01045	COG2234	aminopeptidase activity
EQH49_RS01060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EQH49_RS01065	COG1518	maintenance of DNA repeat elements
EQH49_RS01080	COG1857	crispr-associated protein
EQH49_RS01095	COG1203	CRISPR-associated helicase, Cas3
EQH49_RS01115	COG0720	synthase
EQH49_RS01120	COG0602	queuosine metabolic process
EQH49_RS01140	COG3956	TIGRFAM MazG family protein
EQH49_RS01145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EQH49_RS01155	COG4999	Histidine kinase
EQH49_RS01155	COG3437	response regulator, receiver
EQH49_RS01155	COG2205	protein histidine kinase activity
EQH49_RS01155	COG3850	Histidine kinase
EQH49_RS01165	COG1929	Belongs to the glycerate kinase type-1 family
EQH49_RS01170	COG4948	Mandelate Racemase Muconate Lactonizing
EQH49_RS01175	COG4948	Mandelate Racemase Muconate Lactonizing
EQH49_RS01180	COG2271	Major facilitator Superfamily
EQH49_RS01185	COG0716	FMN binding
EQH49_RS01190	COG0564	pseudouridine synthase activity
EQH49_RS01195	COG3098	single-species biofilm formation
EQH49_RS01210	COG1611	Belongs to the LOG family
EQH49_RS01215	COG0814	amino acid
EQH49_RS01220	COG1760	l-serine dehydratase
EQH49_RS01225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EQH49_RS01235	COG0477	Major facilitator Superfamily
EQH49_RS01245	COG1464	Belongs to the NlpA lipoprotein family
EQH49_RS01250	COG2011	ABC-type metal ion transport system permease component
EQH49_RS01255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EQH49_RS01270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQH49_RS01285	COG1454	alcohol dehydrogenase
EQH49_RS01290	COG0235	Class ii aldolase
EQH49_RS01295	COG0738	Major facilitator superfamily
EQH49_RS01315	COG1349	DNA-binding transcription factor activity
EQH49_RS01325	COG2363	Small membrane protein
EQH49_RS01330	COG0583	DNA-binding transcription factor activity
EQH49_RS01340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EQH49_RS01345	COG2166	iron-sulfur cluster assembly
EQH49_RS01350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EQH49_RS01355	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EQH49_RS01520	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EQH49_RS01550	COG1454	alcohol dehydrogenase
EQH49_RS01550	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS01555	COG4656	Part of a membrane complex involved in electron transport
EQH49_RS01585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EQH49_RS01590	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQH49_RS01595	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EQH49_RS01595	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EQH49_RS01605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EQH49_RS01610	COG1074	ATP-dependent DNA helicase activity
EQH49_RS01615	COG1025	Belongs to the peptidase M16 family
EQH49_RS01620	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EQH49_RS01625	COG4967	type IV pilus modification protein PilV
EQH49_RS01635	COG4795	General secretion pathway protein
EQH49_RS01640	COG2165	general secretion pathway protein
EQH49_RS01675	COG0861	Integral membrane protein TerC family
EQH49_RS01685	COG0667	Aldo Keto reductase
EQH49_RS01700	COG1609	Transcriptional regulator
EQH49_RS01710	COG2186	Transcriptional regulator
EQH49_RS01715	COG2723	6-phospho-beta-galactosidase activity
EQH49_RS01720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQH49_RS01725	COG1609	Transcriptional regulator
EQH49_RS01735	COG0583	DNA-binding transcription factor activity
EQH49_RS01740	COG1794	racemase activity, acting on amino acids and derivatives
EQH49_RS01745	COG1917	Cupin 2, conserved barrel domain protein
EQH49_RS01750	COG1175	transmembrane transport
EQH49_RS01755	COG0395	ABC-type sugar transport system, permease component
EQH49_RS01760	COG3842	ATPase activity
EQH49_RS01790	COG2814	Major facilitator Superfamily
EQH49_RS01795	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS01800	COG0823	Involved in the tonB-independent uptake of proteins
EQH49_RS01810	COG0183	Belongs to the thiolase family
EQH49_RS01825	COG0814	amino acid
EQH49_RS01830	COG0667	Aldo Keto reductase
EQH49_RS01880	COG0697	spore germination
EQH49_RS01885	COG1846	Transcriptional regulator
EQH49_RS01890	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EQH49_RS01900	COG0582	viral genome integration into host DNA
EQH49_RS01905	COG4974	Belongs to the 'phage' integrase family
EQH49_RS01915	COG3539	Fimbrial protein
EQH49_RS01920	COG3121	Chaperone
EQH49_RS01925	COG3188	usher protein
EQH49_RS01930	COG3539	Fimbrial protein
EQH49_RS01935	COG3539	Fimbrial protein
EQH49_RS01940	COG3539	Fimbrial protein
EQH49_RS01950	COG2388	GCN5-related N-acetyl-transferase
EQH49_RS01955	COG3592	Divergent 4Fe-4S mono-cluster
EQH49_RS01970	COG1289	transmembrane transporter activity
EQH49_RS01975	COG1538	Outer membrane efflux protein
EQH49_RS01990	COG1393	Belongs to the ArsC family
EQH49_RS01995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EQH49_RS02030	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQH49_RS02035	COG0667	Aldo Keto reductase
EQH49_RS02050	COG2814	Major facilitator Superfamily
EQH49_RS02060	COG4942	peptidase
EQH49_RS02080	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EQH49_RS02090	COG4974	Belongs to the 'phage' integrase family
EQH49_RS02095	COG0716	FMN binding
EQH49_RS02105	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EQH49_RS02115	COG1272	protein, Hemolysin III
EQH49_RS02125	COG1737	Transcriptional regulator
EQH49_RS02130	COG2723	6-phospho-beta-galactosidase activity
EQH49_RS02150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQH49_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS02180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EQH49_RS02185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EQH49_RS02190	COG0006	proline dipeptidase activity
EQH49_RS02210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EQH49_RS02215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EQH49_RS02230	COG2968	Membrane
EQH49_RS02240	COG0668	transmembrane transport
EQH49_RS02245	COG0191	fructose-bisphosphate aldolase activity
EQH49_RS02260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EQH49_RS02265	COG0501	Belongs to the peptidase M48B family
EQH49_RS02285	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
EQH49_RS02290	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS02320	COG1414	Transcriptional regulator
EQH49_RS02325	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS02340	COG2146	nitrite reductase [NAD(P)H] activity
EQH49_RS02375	COG2814	Major facilitator Superfamily
EQH49_RS02385	COG2356	endonuclease I
EQH49_RS02390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EQH49_RS02415	COG2805	Type II/IV secretion system protein
EQH49_RS02420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EQH49_RS02425	COG0762	integral membrane protein
EQH49_RS02440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EQH49_RS02455	COG4214	carbohydrate transport
EQH49_RS02465	COG3171	Protein conserved in bacteria
EQH49_RS02475	COG1194	a g-specific adenine glycosylase
EQH49_RS02490	COG2211	Major facilitator Superfamily
EQH49_RS02495	COG1982	Orn Lys Arg decarboxylase major
EQH49_RS02505	COG1811	Na channel or pump
EQH49_RS02520	COG0626	cystathionine gamma-synthase activity
EQH49_RS02525	COG0583	DNA-binding transcription factor activity
EQH49_RS02545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQH49_RS02550	COG0754	glutathionylspermidine amidase activity
EQH49_RS02560	COG0625	glutathione transferase activity
EQH49_RS02580	COG0848	biopolymer transport protein
EQH49_RS02590	COG0626	cystathionine gamma-synthase activity
EQH49_RS02595	COG0586	Pfam SNARE associated Golgi protein
EQH49_RS02600	COG2207	Transcriptional regulator
EQH49_RS02605	COG1979	alcohol dehydrogenase
EQH49_RS02610	COG0656	L-ascorbic acid biosynthetic process
EQH49_RS02620	COG1032	radical SAM domain protein
EQH49_RS02625	COG2132	Multicopper oxidase
EQH49_RS02630	COG0204	Acyl-transferase
EQH49_RS02635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EQH49_RS02640	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EQH49_RS02645	COG3111	PFAM Bacterial OB fold (BOF) protein
EQH49_RS02655	COG0642	Histidine kinase
EQH49_RS02660	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQH49_RS02665	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EQH49_RS02675	COG3150	esterase
EQH49_RS02680	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EQH49_RS02685	COG3151	Protein conserved in bacteria
EQH49_RS02690	COG0494	nUDIX hydrolase
EQH49_RS02705	COG0754	glutathionylspermidine amidase activity
EQH49_RS02710	COG3384	dioxygenase
EQH49_RS02725	COG2960	long-chain fatty acid transporting porin activity
EQH49_RS02745	COG3025	triphosphatase activity
EQH49_RS02750	COG4991	sh3 domain protein
EQH49_RS02765	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EQH49_RS02825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EQH49_RS02830	COG0358	DNA primase activity
EQH49_RS02835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EQH49_RS02860	COG2197	response regulator
EQH49_RS02865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQH49_RS02865	COG2205	protein histidine kinase activity
EQH49_RS02865	COG2198	Histidine kinase
EQH49_RS02865	COG0784	Response regulator, receiver
EQH49_RS02875	COG3247	response to pH
EQH49_RS02945	COG2376	Dihydroxyacetone kinase
EQH49_RS02950	COG1461	Dihydroxyacetone kinase
EQH49_RS02965	COG2375	cellular response to nickel ion
EQH49_RS02970	COG1695	Transcriptional regulator
EQH49_RS03020	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQH49_RS03020	COG1902	pentaerythritol trinitrate reductase activity
EQH49_RS03040	COG1451	nucleotide metabolic process
EQH49_RS03045	COG0673	inositol 2-dehydrogenase activity
EQH49_RS03050	COG0861	Integral membrane protein TerC family
EQH49_RS03065	COG2721	sulfolactate sulfo-lyase activity
EQH49_RS03075	COG2271	Major facilitator Superfamily
EQH49_RS03080	COG2186	Transcriptional regulator
EQH49_RS03085	COG0586	Pfam SNARE associated Golgi protein
EQH49_RS03095	COG1422	Protein of unknown function (DUF1090)
EQH49_RS03100	COG4575	ribosome binding
EQH49_RS03105	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EQH49_RS03115	COG2259	Doxx family
EQH49_RS03120	COG0435	Glutathione S-transferase
EQH49_RS03125	COG3152	Membrane
EQH49_RS03130	COG0583	DNA-binding transcription factor activity
EQH49_RS03135	COG1741	Belongs to the pirin family
EQH49_RS03160	COG1929	Belongs to the glycerate kinase type-1 family
EQH49_RS03165	COG2084	Dehydrogenase
EQH49_RS03175	COG2271	Major facilitator Superfamily
EQH49_RS03185	COG2721	sulfolactate sulfo-lyase activity
EQH49_RS03190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQH49_RS03195	COG1349	DNA-binding transcription factor activity
EQH49_RS03205	COG1105	Belongs to the carbohydrate kinase PfkB family
EQH49_RS03210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQH49_RS03210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQH49_RS03210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS03215	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS03215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS03225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS03230	COG3414	Phosphotransferase system galactitol-specific IIB component
EQH49_RS03235	COG3775	system Galactitol-specific IIC component
EQH49_RS03240	COG1063	alcohol dehydrogenase
EQH49_RS03255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EQH49_RS03275	COG2823	Periplasmic or secreted lipoprotein
EQH49_RS03280	COG0701	Predicted permease
EQH49_RS03285	COG0702	epimerase
EQH49_RS03290	COG0693	protein deglycase activity
EQH49_RS03305	COG3153	acetyltransferase
EQH49_RS03310	COG3154	lipid carrier protein
EQH49_RS03315	COG0826	peptidase U32
EQH49_RS03320	COG0826	peptidase U32
EQH49_RS03325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQH49_RS03380	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EQH49_RS03405	COG0814	amino acid
EQH49_RS03450	COG0195	Participates in both transcription termination and antitermination
EQH49_RS03490	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EQH49_RS03500	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EQH49_RS03505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EQH49_RS03515	COG1534	Rna-binding protein
EQH49_RS03525	COG2027	D-alanyl-D-alanine carboxypeptidase
EQH49_RS03535	COG0697	spore germination
EQH49_RS03550	COG0142	geranyltranstransferase activity
EQH49_RS03555	COG3423	Transcriptional regulator
EQH49_RS03565	COG5007	Belongs to the BolA IbaG family
EQH49_RS03570	COG3113	response to antibiotic
EQH49_RS03575	COG2854	intermembrane phospholipid transfer
EQH49_RS03580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EQH49_RS03585	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EQH49_RS03590	COG1127	ABC transporter
EQH49_RS03600	COG0530	calcium, potassium:sodium antiporter activity
EQH49_RS03610	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EQH49_RS03615	COG3117	lipopolysaccharide transmembrane transporter activity
EQH49_RS03620	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EQH49_RS03625	COG1137	ATPase activity
EQH49_RS03630	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EQH49_RS03635	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EQH49_RS03640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS03650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS03655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQH49_RS03660	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EQH49_RS03665	COG5002	protein histidine kinase activity
EQH49_RS03665	COG2198	Histidine kinase
EQH49_RS03665	COG0784	Response regulator, receiver
EQH49_RS03670	COG1312	Catalyzes the dehydration of D-mannonate
EQH49_RS03675	COG1063	alcohol dehydrogenase
EQH49_RS03680	COG2271	Major facilitator Superfamily
EQH49_RS03685	COG1242	4 iron, 4 sulfur cluster binding
EQH49_RS03690	COG0067	glutamate synthase
EQH49_RS03690	COG0069	glutamate synthase activity
EQH49_RS03690	COG0070	glutamate synthase
EQH49_RS03695	COG0493	'glutamate synthase
EQH49_RS03705	COG2969	positive regulation of protein catabolic process
EQH49_RS03710	COG0625	glutathione transferase activity
EQH49_RS03725	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EQH49_RS03730	COG3105	Protein conserved in bacteria
EQH49_RS03735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQH49_RS03740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQH49_RS03765	COG2732	(Barnase) inhibitor
EQH49_RS03770	COG1289	transmembrane transporter activity
EQH49_RS03785	COG0583	DNA-binding transcription factor activity
EQH49_RS03790	COG0312	modulator of DNA gyrase
EQH49_RS03795	COG3164	Protein of unknown function
EQH49_RS03800	COG1530	ribonuclease E activity
EQH49_RS03810	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EQH49_RS03815	COG1792	Involved in formation and maintenance of cell shape
EQH49_RS03820	COG1077	Cell shape determining protein MreB Mrl
EQH49_RS03825	COG2199	diguanylate cyclase activity
EQH49_RS03825	COG2200	EAL domain
EQH49_RS03850	COG0511	ligase activity, forming carbon-carbon bonds
EQH49_RS03855	COG0439	Biotin carboxylase
EQH49_RS03860	COG3924	membrane
EQH49_RS03865	COG4145	pantothenate transmembrane transporter activity
EQH49_RS03890	COG1309	transcriptional regulator
EQH49_RS03895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQH49_RS03900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EQH49_RS03935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EQH49_RS03955	COG0551	DNA topoisomerase type I activity
EQH49_RS03965	COG0758	DNA mediated transformation
EQH49_RS03995	COG3036	rescue of stalled ribosome
EQH49_RS04000	COG0789	Transcriptional regulator
EQH49_RS04015	COG0202	RNA polymerase activity
EQH49_RS04040	COG0201	protein transport
EQH49_RS04105	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EQH49_RS04120	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EQH49_RS04145	COG0051	transcription antitermination factor activity, RNA binding
EQH49_RS04200	COG2964	Protein conserved in bacteria
EQH49_RS04205	COG0545	Peptidyl-prolyl cis-trans isomerase
EQH49_RS04215	COG1047	Peptidyl-prolyl cis-trans
EQH49_RS04220	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EQH49_RS04235	COG0488	(ABC) transporter
EQH49_RS04245	COG0429	hydrolase of the alpha beta-hydrolase fold
EQH49_RS04255	COG3954	Phosphoribulokinase
EQH49_RS04260	COG1765	OsmC-like protein
EQH49_RS04270	COG1289	transmembrane transporter activity
EQH49_RS04275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EQH49_RS04300	COG0738	Major facilitator superfamily
EQH49_RS04305	COG0402	S-adenosylhomocysteine deaminase activity
EQH49_RS04310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQH49_RS04335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EQH49_RS04340	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EQH49_RS04345	COG3266	domain, Protein
EQH49_RS04360	COG4796	Type ii and iii secretion system protein
EQH49_RS04385	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EQH49_RS04390	COG0494	nUDIX hydrolase
EQH49_RS04400	COG1011	Hydrolase
EQH49_RS04405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EQH49_RS04430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EQH49_RS04435	COG2183	response to ionizing radiation
EQH49_RS04440	COG1918	ferrous iron import across plasma membrane
EQH49_RS04465	COG1040	competence protein
EQH49_RS04475	COG2610	gluconate transmembrane transporter activity
EQH49_RS04480	COG1640	4-alpha-glucanotransferase
EQH49_RS04485	COG0058	SHG alpha-glucan phosphorylase activity
EQH49_RS04495	COG1349	DNA-binding transcription factor activity
EQH49_RS04510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EQH49_RS04525	COG0058	SHG alpha-glucan phosphorylase activity
EQH49_RS04550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EQH49_RS04560	COG2610	gluconate transmembrane transporter activity
EQH49_RS04565	COG3265	gluconokinase activity
EQH49_RS04570	COG1609	Transcriptional regulator
EQH49_RS04575	COG1741	Belongs to the pirin family
EQH49_RS04580	COG0673	inositol 2-dehydrogenase activity
EQH49_RS04590	COG1247	-acetyltransferase
EQH49_RS04595	COG0405	Gamma-glutamyltransferase
EQH49_RS04605	COG0584	glycerophosphoryl diester phosphodiesterase
EQH49_RS04655	COG0559	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS04660	COG0683	leucine binding
EQH49_RS04675	COG0683	leucine binding
EQH49_RS04685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EQH49_RS04700	COG2177	Part of the ABC transporter FtsEX involved in
EQH49_RS04705	COG2884	Cell division ATP-binding protein ftsE
EQH49_RS04710	COG0552	protein localization to endoplasmic reticulum
EQH49_RS04715	COG0742	ribosomal rna small subunit methyltransferase
EQH49_RS04720	COG3776	membrane
EQH49_RS04730	COG3714	YhhN family
EQH49_RS04745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EQH49_RS04755	COG0477	Major facilitator Superfamily
EQH49_RS04760	COG0628	permease
EQH49_RS04800	COG3479	Phenolic acid decarboxylase
EQH49_RS04810	COG0747	negative chemotaxis
EQH49_RS04815	COG0601	transmembrane transport
EQH49_RS04820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQH49_RS04830	COG1124	(ABC) transporter
EQH49_RS04840	COG2239	Acts as a magnesium transporter
EQH49_RS04845	COG2081	HI0933 family
EQH49_RS04850	COG0306	phosphate transporter
EQH49_RS04860	COG0589	response to stress
EQH49_RS04880	COG0671	phosphoesterase, PA-phosphatase related
EQH49_RS04885	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EQH49_RS04890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQH49_RS04900	COG1454	alcohol dehydrogenase
EQH49_RS04910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQH49_RS04915	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS04920	COG0583	DNA-binding transcription factor activity
EQH49_RS04925	COG1295	ribonuclease BN
EQH49_RS04930	COG0477	Major facilitator Superfamily
EQH49_RS04935	COG2982	Protein involved in outer membrane biogenesis
EQH49_RS04950	COG0612	Peptidase, M16
EQH49_RS04960	COG2200	EAL domain
EQH49_RS04960	COG2199	diguanylate cyclase activity
EQH49_RS04965	COG3118	belongs to the thioredoxin family
EQH49_RS04965	COG0457	Tetratricopeptide repeat
EQH49_RS04970	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EQH49_RS04975	COG1215	transferase activity, transferring glycosyl groups
EQH49_RS05005	COG2194	sulfuric ester hydrolase activity
EQH49_RS05020	COG0457	Tetratricopeptide repeat
EQH49_RS05025	COG1215	transferase activity, transferring glycosyl groups
EQH49_RS05035	COG2894	cell division
EQH49_RS05045	COG4608	Belongs to the ABC transporter superfamily
EQH49_RS05050	COG0444	Belongs to the ABC transporter superfamily
EQH49_RS05055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQH49_RS05060	COG0601	transmembrane transport
EQH49_RS05065	COG0747	negative chemotaxis
EQH49_RS05090	COG2223	nitrite transmembrane transporter activity
EQH49_RS05095	COG5571	outer membrane autotransporter
EQH49_RS05100	COG2818	Glycosylase
EQH49_RS05105	COG0456	acetyltransferase
EQH49_RS05110	COG0243	molybdopterin cofactor binding
EQH49_RS05115	COG2885	chlorophyll binding
EQH49_RS05120	COG1609	Transcriptional regulator
EQH49_RS05130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQH49_RS05155	COG2814	Major facilitator Superfamily
EQH49_RS05160	COG2944	sequence-specific DNA binding
EQH49_RS05165	COG1278	Cold shock
EQH49_RS05195	COG3274	enterobacterial common antigen metabolic process
EQH49_RS05200	COG4682	membrane
EQH49_RS05205	COG4682	membrane
EQH49_RS05220	COG4213	ABC transporter substrate-binding protein
EQH49_RS05230	COG4214	carbohydrate transport
EQH49_RS05235	COG2207	Transcriptional regulator
EQH49_RS05235	COG1609	Transcriptional regulator
EQH49_RS05240	COG2992	FlgJ-related protein
EQH49_RS05245	COG0366	Alpha amylase catalytic
EQH49_RS05250	COG3977	Valine--pyruvate aminotransferase
EQH49_RS05255	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EQH49_RS05260	COG1414	Transcriptional regulator
EQH49_RS05265	COG3276	selenocysteine insertion sequence binding
EQH49_RS05275	COG0625	glutathione transferase activity
EQH49_RS05295	COG3722	fumarate hydratase activity
EQH49_RS05315	COG2186	Transcriptional regulator
EQH49_RS05325	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EQH49_RS05350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EQH49_RS05355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQH49_RS05365	COG4942	peptidase
EQH49_RS05370	COG2861	carbohydrate metabolic process
EQH49_RS05375	COG0463	Glycosyl transferase, family 2
EQH49_RS05385	COG0156	8-amino-7-oxononanoate synthase activity
EQH49_RS05400	COG0859	PFAM glycosyl transferase family 9
EQH49_RS05405	COG0438	transferase activity, transferring glycosyl groups
EQH49_RS05410	COG3307	-O-antigen
EQH49_RS05415	COG1442	glycosyl transferase family 8
EQH49_RS05415	COG1216	Glycosyl transferase, family 2
EQH49_RS05425	COG0859	PFAM glycosyl transferase family 9
EQH49_RS05435	COG0438	transferase activity, transferring glycosyl groups
EQH49_RS05440	COG1216	Glycosyl transferase, family 2
EQH49_RS05445	COG1519	Transferase
EQH49_RS05480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EQH49_RS05505	COG0842	Transport permease protein
EQH49_RS05510	COG1131	(ABC) transporter
EQH49_RS05525	COG1561	YicC-like family, N-terminal region
EQH49_RS05530	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EQH49_RS05535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EQH49_RS05535	COG2169	Transcriptional regulator
EQH49_RS05545	COG2860	membrane
EQH49_RS05565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EQH49_RS05570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQH49_RS05575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EQH49_RS05580	COG1494	fructose-1,6-bisphosphatase
EQH49_RS05590	COG3152	Membrane
EQH49_RS05615	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EQH49_RS05635	COG0786	glutamate:sodium symporter activity
EQH49_RS05640	COG2233	PERMEase
EQH49_RS05645	COG2982	Protein involved in outer membrane biogenesis
EQH49_RS05650	COG1263	PTS System
EQH49_RS05650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQH49_RS05655	COG1486	melibiose metabolic process
EQH49_RS05665	COG1501	Belongs to the glycosyl hydrolase 31 family
EQH49_RS05670	COG2211	Major facilitator Superfamily
EQH49_RS05740	COG1064	alcohol dehydrogenase
EQH49_RS05750	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EQH49_RS05765	COG1464	Belongs to the NlpA lipoprotein family
EQH49_RS05790	COG0583	DNA-binding transcription factor activity
EQH49_RS05825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EQH49_RS05835	COG2814	Major facilitator Superfamily
EQH49_RS05845	COG1263	PTS System
EQH49_RS05845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQH49_RS05850	COG0697	spore germination
EQH49_RS05865	COG2828	Protein conserved in bacteria
EQH49_RS05870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EQH49_RS05875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EQH49_RS05880	COG0583	DNA-binding transcription factor activity
EQH49_RS05885	COG3384	dioxygenase
EQH49_RS05895	COG1609	Transcriptional regulator
EQH49_RS05905	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQH49_RS05905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQH49_RS05910	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQH49_RS05915	COG4580	involved in the transport of maltose and maltodextrins
EQH49_RS05940	COG2188	Transcriptional regulator
EQH49_RS05985	COG2271	Major facilitator Superfamily
EQH49_RS05995	COG2197	response regulator
EQH49_RS06000	COG0440	acetolactate synthase activity
EQH49_RS06005	COG0028	Belongs to the TPP enzyme family
EQH49_RS06030	COG2814	Major facilitator Superfamily
EQH49_RS06035	COG0583	DNA-binding transcription factor activity
EQH49_RS06040	COG2610	gluconate transmembrane transporter activity
EQH49_RS06060	COG2149	membrane
EQH49_RS06075	COG2188	Transcriptional regulator
EQH49_RS06100	COG5645	(Lipo)protein
EQH49_RS06105	COG0823	Involved in the tonB-independent uptake of proteins
EQH49_RS06110	COG2271	Major facilitator Superfamily
EQH49_RS06120	COG0800	Aldolase
EQH49_RS06125	COG3734	2-keto-3-deoxy-galactonokinase
EQH49_RS06130	COG2186	Transcriptional regulator
EQH49_RS06145	COG0561	phosphatase activity
EQH49_RS06150	COG0187	DNA topoisomerase II activity
EQH49_RS06180	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EQH49_RS06210	COG2091	lysine biosynthetic process via aminoadipic acid
EQH49_RS06215	COG0431	NADPH-dependent FMN reductase
EQH49_RS06220	COG2252	PERMEase
EQH49_RS06230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQH49_RS06235	COG0363	glucosamine-6-phosphate deaminase activity
EQH49_RS06240	COG2382	esterase
EQH49_RS06255	COG0704	Plays a role in the regulation of phosphate uptake
EQH49_RS06260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQH49_RS06265	COG0581	inorganic phosphate transmembrane transporter activity
EQH49_RS06270	COG0573	inorganic phosphate transmembrane transporter activity
EQH49_RS06275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EQH49_RS06280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EQH49_RS06335	COG3312	ion transport
EQH49_RS06350	COG0716	FMN binding
EQH49_RS06355	COG1522	sequence-specific DNA binding
EQH49_RS06385	COG1129	ABC transporter
EQH49_RS06390	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS06400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQH49_RS06405	COG1609	Transcriptional regulator
EQH49_RS06410	COG0477	Major facilitator Superfamily
EQH49_RS06415	COG2186	Transcriptional regulator
EQH49_RS06445	COG1763	Mo-molybdopterin cofactor biosynthetic process
EQH49_RS06455	COG3084	Protein conserved in bacteria
EQH49_RS06460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EQH49_RS06470	COG0204	Acyl-transferase
EQH49_RS06495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EQH49_RS06510	COG3852	Histidine kinase
EQH49_RS06525	COG1011	Hydrolase
EQH49_RS06540	COG0456	acetyltransferase
EQH49_RS06550	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EQH49_RS06565	COG2864	formate dehydrogenase
EQH49_RS06570	COG0437	4 iron, 4 sulfur cluster binding
EQH49_RS06590	COG0205	6-phosphofructokinase activity
EQH49_RS06650	COG2211	Major facilitator Superfamily
EQH49_RS06660	COG1454	alcohol dehydrogenase
EQH49_RS06665	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS06670	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS06675	COG1129	ABC transporter
EQH49_RS06720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EQH49_RS06725	COG2258	MOSC domain
EQH49_RS06730	COG2205	protein histidine kinase activity
EQH49_RS06735	COG0745	RESPONSE REGULATOR receiver
EQH49_RS06740	COG3678	ATP-independent chaperone mediated protein folding
EQH49_RS06760	COG1575	Belongs to the MenA family. Type 1 subfamily
EQH49_RS06775	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EQH49_RS06780	COG1609	Transcriptional regulator
EQH49_RS06785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EQH49_RS06800	COG0626	cystathionine gamma-synthase activity
EQH49_RS06805	COG0460	homoserine dehydrogenase
EQH49_RS06805	COG0527	aspartate kinase activity
EQH49_RS06815	COG0737	Belongs to the 5'-nucleotidase family
EQH49_RS06825	COG0583	DNA-binding transcription factor activity
EQH49_RS06835	COG0697	spore germination
EQH49_RS06840	COG0371	Dehydrogenase
EQH49_RS06850	COG2207	Transcriptional regulator
EQH49_RS06855	COG3443	Belongs to the bacterial solute-binding protein 9 family
EQH49_RS06870	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EQH49_RS06885	COG0583	DNA-binding transcription factor activity
EQH49_RS06960	COG3085	chromosome segregation
EQH49_RS06980	COG3978	acetolactate synthase activity
EQH49_RS06995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EQH49_RS07000	COG0583	DNA-binding transcription factor activity
EQH49_RS07010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQH49_RS07015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQH49_RS07025	COG1811	Na channel or pump
EQH49_RS07050	COG3118	belongs to the thioredoxin family
EQH49_RS07060	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EQH49_RS07065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQH49_RS07075	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EQH49_RS07080	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EQH49_RS07085	COG1088	dTDP-glucose 4,6-dehydratase activity
EQH49_RS07090	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EQH49_RS07095	COG0456	acetyltransferase
EQH49_RS07100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EQH49_RS07105	COG2244	polysaccharide biosynthetic process
EQH49_RS07150	COG3071	HemY protein
EQH49_RS07155	COG2959	enzyme of heme biosynthesis
EQH49_RS07170	COG3072	Adenylate cyclase
EQH49_RS07200	COG1011	Hydrolase
EQH49_RS07205	COG0210	DNA helicase
EQH49_RS07235	COG1280	lysine exporter protein (LysE YggA)
EQH49_RS07245	COG1280	lysine exporter protein (LysE YggA)
EQH49_RS07250	COG2267	carboxylic ester hydrolase activity
EQH49_RS07255	COG0561	phosphatase activity
EQH49_RS07260	COG0697	spore germination
EQH49_RS07265	COG0583	DNA-binding transcription factor activity
EQH49_RS07295	COG3165	ubiquinone biosynthetic process from chorismate
EQH49_RS07315	COG0805	protein transport
EQH49_RS07355	COG1739	Uncharacterized protein family UPF0029
EQH49_RS07365	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EQH49_RS07395	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EQH49_RS07440	COG0250	Participates in transcription elongation, termination and antitermination
EQH49_RS07475	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EQH49_RS07480	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQH49_RS07490	COG3706	GGDEF domain
EQH49_RS07505	COG2104	thiamine diphosphate biosynthetic process
EQH49_RS07510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EQH49_RS07525	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EQH49_RS07560	COG3678	ATP-independent chaperone mediated protein folding
EQH49_RS07565	COG4191	Histidine kinase
EQH49_RS07575	COG0151	Belongs to the GarS family
EQH49_RS07605	COG0456	acetyltransferase
EQH49_RS07615	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EQH49_RS07665	COG0527	aspartate kinase activity
EQH49_RS07675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EQH49_RS07685	COG0251	oxidation-reduction process
EQH49_RS07730	COG4580	involved in the transport of maltose and maltodextrins
EQH49_RS07755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EQH49_RS07765	COG0534	Mate efflux family protein
EQH49_RS07770	COG3237	CsbD-like
EQH49_RS07775	COG0735	belongs to the Fur family
EQH49_RS07785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EQH49_RS07800	COG0305	Participates in initiation and elongation during chromosome replication
EQH49_RS07805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EQH49_RS07820	COG0432	Pfam Uncharacterised protein family UPF0047
EQH49_RS07825	COG2315	Protein conserved in bacteria
EQH49_RS07840	COG0741	lytic transglycosylase activity
EQH49_RS07845	COG4771	TonB-dependent receptor
EQH49_RS07865	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EQH49_RS07880	COG0483	inositol monophosphate 1-phosphatase activity
EQH49_RS07885	COG1609	Transcriptional regulator
EQH49_RS07890	COG1234	tRNA 3'-trailer cleavage
EQH49_RS07925	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EQH49_RS07935	COG0789	Transcriptional regulator
EQH49_RS07940	COG0625	glutathione transferase activity
EQH49_RS07945	COG2252	PERMEase
EQH49_RS07950	COG0025	NhaP-type Na H and K H
EQH49_RS07955	COG0583	DNA-binding transcription factor activity
EQH49_RS07960	COG1380	Effector of murein hydrolase LrgA
EQH49_RS07965	COG1346	cytolysis
EQH49_RS07970	COG3539	Fimbrial protein
EQH49_RS08000	COG3162	membrane
EQH49_RS08005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQH49_RS08015	COG1301	dicarboxylic acid transport
EQH49_RS08020	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EQH49_RS08055	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS08060	COG1129	ABC transporter
EQH49_RS08065	COG0784	Response regulator, receiver
EQH49_RS08065	COG4191	Histidine kinase
EQH49_RS08075	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EQH49_RS08085	COG3454	Phosphonate metabolism
EQH49_RS08090	COG4778	phosphonate C-P lyase system protein PhnL
EQH49_RS08095	COG4107	phosphonate C-P lyase system protein PhnK
EQH49_RS08100	COG3627	carbon phosphorus lyase activity
EQH49_RS08105	COG3626	phosphonate metabolism
EQH49_RS08110	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EQH49_RS08115	COG3624	Phosphonate C-P lyase system protein PhnG
EQH49_RS08120	COG2188	Transcriptional regulator
EQH49_RS08125	COG2764	glyoxalase bleomycin resistance protein dioxygenase
EQH49_RS08130	COG2824	Alkylphosphonate utilization operon protein PhnA
EQH49_RS08145	COG2169	Transcriptional regulator
EQH49_RS08150	COG1486	melibiose metabolic process
EQH49_RS08185	COG0861	Integral membrane protein TerC family
EQH49_RS08205	COG1215	transferase activity, transferring glycosyl groups
EQH49_RS08210	COG1649	PFAM Uncharacterised BCR, COG1649
EQH49_RS08210	COG0726	polysaccharide deacetylase
EQH49_RS08215	COG0457	Tetratricopeptide repeat
EQH49_RS08260	COG1309	transcriptional regulator
EQH49_RS08275	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EQH49_RS08280	COG1027	Aspartate ammonia-lyase
EQH49_RS08285	COG3030	protein affecting phage T7 exclusion by the F plasmid
EQH49_RS08290	COG0531	amino acid
EQH49_RS08315	COG3539	Fimbrial protein
EQH49_RS08320	COG3188	usher protein
EQH49_RS08355	COG0745	RESPONSE REGULATOR receiver
EQH49_RS08360	COG1509	lysine 2,3-aminomutase activity
EQH49_RS08375	COG5510	response to toxic substance
EQH49_RS08380	COG2076	Multidrug Resistance protein
EQH49_RS08400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EQH49_RS08405	COG1053	succinate dehydrogenase
EQH49_RS08420	COG3264	Mechanosensitive ion channel
EQH49_RS08420	COG1511	domain protein
EQH49_RS08440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQH49_RS08460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EQH49_RS08465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EQH49_RS08465	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EQH49_RS08470	COG0802	atpase or kinase
EQH49_RS08475	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQH49_RS08495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EQH49_RS08500	COG0330	HflC and HflK could
EQH49_RS08505	COG0330	HflC and HflK could
EQH49_RS08515	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EQH49_RS08530	COG0557	exoribonuclease II activity
EQH49_RS08535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQH49_RS08540	COG1960	acyl-CoA dehydrogenase activity
EQH49_RS08550	COG3650	response to hydrogen peroxide
EQH49_RS08555	COG1073	alpha beta
EQH49_RS08615	COG2965	DNA replication, synthesis of RNA primer
EQH49_RS08620	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EQH49_RS08630	COG3061	Opacity-associated protein A
EQH49_RS08635	COG0545	Peptidyl-prolyl cis-trans isomerase
EQH49_RS08640	COG1113	amino acid transport
EQH49_RS08650	COG0697	spore germination
EQH49_RS08660	COG0702	epimerase
EQH49_RS08665	COG1733	regulation of RNA biosynthetic process
EQH49_RS08680	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EQH49_RS08705	COG1253	flavin adenine dinucleotide binding
EQH49_RS08715	COG0729	surface antigen
EQH49_RS08720	COG2911	Protein conserved in bacteria
EQH49_RS08725	COG2105	PFAM AIG2 family protein
EQH49_RS08740	COG1879	ABC-type sugar transport system periplasmic component
EQH49_RS08745	COG1129	ABC transporter
EQH49_RS08750	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS08755	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS08765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EQH49_RS08785	COG0312	modulator of DNA gyrase
EQH49_RS08820	COG3964	amidohydrolase
EQH49_RS08835	COG2706	6-phosphogluconolactonase activity
EQH49_RS08840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS08840	COG3711	transcriptional antiterminator
EQH49_RS08845	COG3077	Addiction module antitoxin, RelB DinJ family
EQH49_RS08850	COG2026	Addiction module toxin, RelE StbE family
EQH49_RS08855	COG0602	queuosine metabolic process
EQH49_RS08875	COG1486	melibiose metabolic process
EQH49_RS08880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQH49_RS08885	COG0366	Alpha amylase catalytic
EQH49_RS08890	COG1263	PTS System
EQH49_RS08890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQH49_RS08930	COG2731	YhcH YjgK YiaL family protein
EQH49_RS08935	COG2222	sugar isomerase
EQH49_RS08940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQH49_RS08945	COG1228	amidohydrolase
EQH49_RS08950	COG1288	antiporter activity
EQH49_RS08955	COG2188	Transcriptional regulator
EQH49_RS08980	COG0525	valine-tRNA ligase activity
EQH49_RS08985	COG2927	DNA polymerase III (CHI subunit)
EQH49_RS08995	COG0795	lipopolysaccharide-transporting ATPase activity
EQH49_RS09000	COG0795	lipopolysaccharide-transporting ATPase activity
EQH49_RS09005	COG0433	COG0433 Predicted ATPase
EQH49_RS09020	COG3718	enzyme involved in inositol metabolism
EQH49_RS09025	COG1737	Transcriptional regulator
EQH49_RS09025	COG0837	glucose binding
EQH49_RS09030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQH49_RS09035	COG3962	Belongs to the TPP enzyme family
EQH49_RS09045	COG1082	Xylose isomerase domain protein TIM barrel
EQH49_RS09060	COG3842	ATPase activity
EQH49_RS09065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EQH49_RS09070	COG0395	ABC-type sugar transport system, permease component
EQH49_RS09075	COG1175	transmembrane transport
EQH49_RS09080	COG1064	alcohol dehydrogenase
EQH49_RS09085	COG0659	secondary active sulfate transmembrane transporter activity
EQH49_RS09090	COG0288	reversible hydration of carbon dioxide
EQH49_RS09100	COG0582	viral genome integration into host DNA
EQH49_RS09120	COG0556	nucleotide-excision repair
EQH49_RS09135	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EQH49_RS09155	COG3596	GTP binding
EQH49_RS09175	COG2003	Belongs to the UPF0758 family
EQH49_RS09270	COG1216	Glycosyl transferase, family 2
EQH49_RS09290	COG3507	Belongs to the glycosyl hydrolase 43 family
EQH49_RS09295	COG2211	Major facilitator Superfamily
EQH49_RS09300	COG2115	Belongs to the xylose isomerase family
EQH49_RS09305	COG4580	involved in the transport of maltose and maltodextrins
EQH49_RS09310	COG3272	Protein of unknown function (DUF1722)
EQH49_RS09330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EQH49_RS09345	COG0300	oxidoreductase activity
EQH49_RS09350	COG3631	Ketosteroid isomerase-related protein
EQH49_RS09355	COG0789	Transcriptional regulator
EQH49_RS09360	COG3040	lipid binding
EQH49_RS09370	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EQH49_RS09375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQH49_RS09380	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQH49_RS09385	COG1538	Outer membrane efflux protein
EQH49_RS09390	COG0745	RESPONSE REGULATOR receiver
EQH49_RS09395	COG5002	protein histidine kinase activity
EQH49_RS09410	COG2850	peptidyl-arginine hydroxylation
EQH49_RS09445	COG0842	Transport permease protein
EQH49_RS09450	COG0842	Transport permease protein
EQH49_RS09450	COG1129	ABC transporter
EQH49_RS09455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQH49_RS09460	COG3706	GGDEF domain
EQH49_RS09485	COG4869	propanediol catabolic process
EQH49_RS09495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EQH49_RS09500	COG1882	Formate acetyltransferase
EQH49_RS09515	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS09515	COG1454	alcohol dehydrogenase
EQH49_RS09550	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQH49_RS09555	COG0583	DNA-binding transcription factor activity
EQH49_RS09570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQH49_RS09575	COG5457	Domain of unknown function (DUF1127)
EQH49_RS09585	COG1566	PFAM secretion protein HlyD family protein
EQH49_RS09600	COG1924	4 iron, 4 sulfur cluster binding
EQH49_RS09605	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
EQH49_RS09620	COG2733	membrane
EQH49_RS09635	COG5464	transposase or invertase
EQH49_RS09640	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS09650	COG0523	cobalamin synthesis protein
EQH49_RS09655	COG2879	small protein
EQH49_RS09660	COG1966	Carbon starvation protein
EQH49_RS09665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EQH49_RS09670	COG2368	4-hydroxyphenylacetate
EQH49_RS09690	COG3971	2-oxopent-4-enoate hydratase activity
EQH49_RS09700	COG3384	dioxygenase
EQH49_RS09705	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS09715	COG0179	Fumarylacetoacetate (FAA) hydrolase
EQH49_RS09720	COG1846	Transcriptional regulator
EQH49_RS09755	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EQH49_RS09770	COG3734	2-keto-3-deoxy-galactonokinase
EQH49_RS09775	COG0800	Aldolase
EQH49_RS09780	COG1737	Transcriptional regulator
EQH49_RS09790	COG1214	PFAM Peptidase M22, glycoprotease
EQH49_RS09790	COG0456	acetyltransferase
EQH49_RS09795	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EQH49_RS09795	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EQH49_RS09810	COG3715	PTS system
EQH49_RS09815	COG3716	PTS system mannose fructose sorbose family IID component
EQH49_RS09820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EQH49_RS09830	COG5464	transposase or invertase
EQH49_RS09845	COG1484	DNA-dependent DNA replication
EQH49_RS09860	COG2966	Psort location CytoplasmicMembrane, score
EQH49_RS09875	COG2197	response regulator
EQH49_RS09880	COG2197	response regulator
EQH49_RS09885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EQH49_RS09890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQH49_RS09890	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQH49_RS09895	COG4114	ferric iron reductase
EQH49_RS09900	COG3706	GGDEF domain
EQH49_RS09930	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EQH49_RS09935	COG0456	acetyltransferase
EQH49_RS09940	COG1011	Hydrolase
EQH49_RS09950	COG2823	Periplasmic or secreted lipoprotein
EQH49_RS09960	COG4667	esterase of the alpha-beta hydrolase superfamily
EQH49_RS09965	COG0084	hydrolase, TatD family'
EQH49_RS09970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQH49_RS10000	COG3726	membrane protein affecting hemolysin expression
EQH49_RS10005	COG0560	Phosphoserine phosphatase
EQH49_RS10010	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EQH49_RS10020	COG0488	(ABC) transporter
EQH49_RS10025	COG0741	lytic transglycosylase activity
EQH49_RS10045	COG3708	Transcriptional regulator
EQH49_RS10045	COG2207	Transcriptional regulator
EQH49_RS10050	COG3045	CreA protein
EQH49_RS10055	COG0745	RESPONSE REGULATOR receiver
EQH49_RS10060	COG2205	protein histidine kinase activity
EQH49_RS10065	COG4452	Inner membrane protein CreD
EQH49_RS10070	COG0745	RESPONSE REGULATOR receiver
EQH49_RS10080	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EQH49_RS10090	COG0460	homoserine dehydrogenase
EQH49_RS10090	COG0527	aspartate kinase activity
EQH49_RS10100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EQH49_RS10115	COG1115	amino acid carrier protein
EQH49_RS10120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EQH49_RS10125	COG0521	Mo-molybdopterin cofactor biosynthetic process
EQH49_RS10130	COG0477	Major facilitator Superfamily
EQH49_RS10135	COG1584	GPR1 FUN34 yaaH family protein
EQH49_RS10140	COG4735	regulation of single-species biofilm formation
EQH49_RS10165	COG0583	DNA-binding transcription factor activity
EQH49_RS10180	COG0196	riboflavin kinase activity
EQH49_RS10195	COG1047	Peptidyl-prolyl cis-trans
EQH49_RS10220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EQH49_RS10285	COG0505	Belongs to the CarA family
EQH49_RS10330	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EQH49_RS10340	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EQH49_RS10345	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EQH49_RS10360	COG3493	citrate carrier protein
EQH49_RS10370	COG0564	pseudouridine synthase activity
EQH49_RS10380	COG0417	DNA replication proofreading
EQH49_RS10385	COG0235	Class ii aldolase
EQH49_RS10405	COG0586	Pfam SNARE associated Golgi protein
EQH49_RS10415	COG1178	ABC-type Fe3 transport system permease component
EQH49_RS10435	COG2814	Major facilitator Superfamily
EQH49_RS10440	COG2271	Major facilitator Superfamily
EQH49_RS10445	COG0583	DNA-binding transcription factor activity
EQH49_RS10455	COG0738	Major facilitator superfamily
EQH49_RS10505	COG0028	Belongs to the TPP enzyme family
EQH49_RS10515	COG1609	Transcriptional regulator
EQH49_RS10535	COG0768	penicillin binding
EQH49_RS10540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EQH49_RS10545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EQH49_RS10560	COG0772	Belongs to the SEDS family
EQH49_RS10585	COG0849	cell division
EQH49_RS10590	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EQH49_RS10610	COG0494	nUDIX hydrolase
EQH49_RS10635	COG1459	type II secretion system
EQH49_RS10640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EQH49_RS10645	COG4969	Belongs to the N-Me-Phe pilin family
EQH49_RS10655	COG3023	N-Acetylmuramoyl-L-alanine amidase
EQH49_RS10660	COG3725	Membrane protein required for beta-lactamase induction
EQH49_RS10665	COG3940	Belongs to the glycosyl hydrolase 43 family
EQH49_RS10670	COG2211	Major facilitator Superfamily
EQH49_RS10675	COG1113	amino acid transport
EQH49_RS10680	COG2186	Transcriptional regulator
EQH49_RS10685	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EQH49_RS10690	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQH49_RS10695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQH49_RS10710	COG3064	Membrane
EQH49_RS10755	COG2132	Multicopper oxidase
EQH49_RS10760	COG4993	Dehydrogenase
EQH49_RS10770	COG0288	reversible hydration of carbon dioxide
EQH49_RS10775	COG1131	(ABC) transporter
EQH49_RS10780	COG0842	Transport permease protein
EQH49_RS10785	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS10790	COG0726	polysaccharide deacetylase
EQH49_RS10810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EQH49_RS10815	COG0617	tRNA 3'-terminal CCA addition
EQH49_RS10835	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EQH49_RS10840	COG1643	Atp-dependent helicase
EQH49_RS10925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQH49_RS10930	COG4774	siderophore transport
EQH49_RS10935	COG1120	ATPase activity
EQH49_RS10940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQH49_RS10945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQH49_RS10965	COG2860	membrane
EQH49_RS10985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQH49_RS10990	COG3835	regulator
EQH49_RS11005	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EQH49_RS11010	COG0024	Methionine aminopeptidase
EQH49_RS11035	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EQH49_RS11050	COG0575	Belongs to the CDS family
EQH49_RS11055	COG0750	zinc metalloprotease
EQH49_RS11065	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EQH49_RS11105	COG1982	Orn Lys Arg decarboxylase major
EQH49_RS11110	COG0346	lactoylglutathione lyase activity
EQH49_RS11120	COG4568	rho-dependent transcription termination
EQH49_RS11135	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EQH49_RS11140	COG3015	lipoprotein NlpE involved in copper resistance
EQH49_RS11145	COG0791	NLP P60 protein
EQH49_RS11155	COG1720	tRNA m6t6A37 methyltransferase activity
EQH49_RS11165	COG1464	Belongs to the NlpA lipoprotein family
EQH49_RS11170	COG2011	ABC-type metal ion transport system permease component
EQH49_RS11180	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EQH49_RS11215	COG0656	L-ascorbic acid biosynthetic process
EQH49_RS11220	COG0583	DNA-binding transcription factor activity
EQH49_RS11225	COG2814	Major facilitator Superfamily
EQH49_RS11235	COG2226	methyltransferase
EQH49_RS11240	COG1388	LysM domain
EQH49_RS11240	COG0741	lytic transglycosylase activity
EQH49_RS11250	COG2226	methyltransferase
EQH49_RS11260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EQH49_RS11270	COG0583	DNA-binding transcription factor activity
EQH49_RS11280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EQH49_RS11285	COG1960	acyl-CoA dehydrogenase activity
EQH49_RS11295	COG0121	glutamine amidotransferase
EQH49_RS11300	COG3034	peptidoglycan biosynthetic process
EQH49_RS11315	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EQH49_RS11320	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EQH49_RS11335	COG2991	Protein conserved in bacteria
EQH49_RS11350	COG0454	-acetyltransferase
EQH49_RS11355	COG2195	Cleaves the N-terminal amino acid of tripeptides
EQH49_RS11375	COG1802	Transcriptional regulator
EQH49_RS11380	COG1113	amino acid transport
EQH49_RS11385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EQH49_RS11390	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS11395	COG0579	oxidoreductase
EQH49_RS11410	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EQH49_RS11425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQH49_RS11430	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQH49_RS11435	COG0022	dehydrogenase e1 component
EQH49_RS11440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQH49_RS11450	COG0511	ligase activity, forming carbon-carbon bonds
EQH49_RS11455	COG0439	Biotin carboxylase
EQH49_RS11460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EQH49_RS11465	COG0697	spore germination
EQH49_RS11480	COG1984	allophanate hydrolase subunit 2
EQH49_RS11485	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EQH49_RS11490	COG0436	Aminotransferase
EQH49_RS11505	COG4221	oxidoreductase activity
EQH49_RS11515	COG0765	amino acid transport
EQH49_RS11520	COG1126	abc transporter atp-binding protein
EQH49_RS11585	COG0582	viral genome integration into host DNA
EQH49_RS11610	COG0791	NLP P60 protein
EQH49_RS11635	COG3639	organic phosphonate transmembrane transporter activity
EQH49_RS11645	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EQH49_RS11670	COG3188	usher protein
EQH49_RS11685	COG0765	amino acid transport
EQH49_RS11690	COG4597	amino acid ABC transporter
EQH49_RS11695	COG1126	abc transporter atp-binding protein
EQH49_RS11700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQH49_RS11740	COG4302	ethanolamine ammonia-lyase activity
EQH49_RS11745	COG4303	Ethanolamine ammonia lyase large subunit
EQH49_RS11755	COG0833	amino acid
EQH49_RS11760	COG2040	homocysteine
EQH49_RS11765	COG4521	taurine ABC transporter
EQH49_RS11770	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EQH49_RS11775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQH49_RS11780	COG2175	clavaminate synthase activity
EQH49_RS11790	COG1943	Transposase
EQH49_RS11795	COG0113	porphobilinogen synthase activity
EQH49_RS11800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQH49_RS11805	COG1335	isochorismatase
EQH49_RS11810	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EQH49_RS11850	COG1785	Belongs to the alkaline phosphatase family
EQH49_RS11860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQH49_RS11870	COG3416	Protein conserved in bacteria
EQH49_RS11875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EQH49_RS11885	COG4126	flavin adenine dinucleotide binding
EQH49_RS11900	COG1940	carbohydrate kinase activity
EQH49_RS11905	COG0419	ATPase involved in DNA repair
EQH49_RS11910	COG0420	3'-5' exonuclease activity
EQH49_RS11935	COG0366	Alpha amylase catalytic
EQH49_RS11940	COG0583	DNA-binding transcription factor activity
EQH49_RS11960	COG1228	amidohydrolase
EQH49_RS11970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQH49_RS11985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS11990	COG0450	alkyl hydroperoxide reductase
EQH49_RS12010	COG1862	Preprotein translocase
EQH49_RS12015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EQH49_RS12020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EQH49_RS12040	COG4238	major outer membrane lipoprotein
EQH49_RS12050	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQH49_RS12050	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQH49_RS12070	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EQH49_RS12075	COG0667	Aldo Keto reductase
EQH49_RS12085	COG0142	geranyltranstransferase activity
EQH49_RS12110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EQH49_RS12120	COG2814	Major facilitator Superfamily
EQH49_RS12125	COG0673	inositol 2-dehydrogenase activity
EQH49_RS12140	COG1053	succinate dehydrogenase
EQH49_RS12150	COG1053	succinate dehydrogenase
EQH49_RS12155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EQH49_RS12160	COG1414	Transcriptional regulator
EQH49_RS12175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EQH49_RS12180	COG1845	cytochrome c oxidase, subunit III
EQH49_RS12185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EQH49_RS12190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EQH49_RS12195	COG2223	nitrite transmembrane transporter activity
EQH49_RS12200	COG3056	Lipoprotein
EQH49_RS12205	COG0271	Belongs to the BolA IbaG family
EQH49_RS12235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EQH49_RS12240	COG0776	regulation of translation
EQH49_RS12245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQH49_RS12250	COG1555	photosystem II stabilization
EQH49_RS12255	COG0824	Thioesterase
EQH49_RS12265	COG4533	DNA binding
EQH49_RS12280	COG1522	sequence-specific DNA binding
EQH49_RS12285	COG1132	(ABC) transporter
EQH49_RS12290	COG1132	(ABC) transporter
EQH49_RS12295	COG0347	Belongs to the P(II) protein family
EQH49_RS12300	COG0004	ammonium transporteR
EQH49_RS12305	COG1946	Acyl-CoA thioesterase
EQH49_RS12310	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EQH49_RS12315	COG3695	enzyme binding
EQH49_RS12345	COG2364	Membrane
EQH49_RS12360	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EQH49_RS12370	COG2182	Extracellular solute-binding protein
EQH49_RS12375	COG1175	transmembrane transport
EQH49_RS12380	COG3833	ABC-type maltose transport systems, permease component
EQH49_RS12385	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EQH49_RS12390	COG1874	Beta-galactosidase
EQH49_RS12435	COG0110	maltose O-acetyltransferase activity
EQH49_RS12450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EQH49_RS12455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQH49_RS12460	COG1309	transcriptional regulator
EQH49_RS12465	COG1196	nuclear chromosome segregation
EQH49_RS12465	COG3264	Mechanosensitive ion channel
EQH49_RS12480	COG3923	Primosomal replication protein n
EQH49_RS12485	COG2832	Protein of unknown function (DUF454)
EQH49_RS12525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQH49_RS12530	COG4651	solute:proton antiporter activity
EQH49_RS12530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EQH49_RS12535	COG2223	nitrite transmembrane transporter activity
EQH49_RS12545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EQH49_RS12550	COG3735	TraB family
EQH49_RS12565	COG1585	Membrane protein implicated in regulation of membrane protease activity
EQH49_RS12570	COG0330	HflC and HflK could
EQH49_RS12575	COG4619	ABC transporter
EQH49_RS12580	COG0390	transport system, permease component
EQH49_RS12590	COG3118	belongs to the thioredoxin family
EQH49_RS12595	COG0300	oxidoreductase activity
EQH49_RS12600	COG2755	lipolytic protein G-D-S-L family
EQH49_RS12605	COG4181	ATPase activity
EQH49_RS12610	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EQH49_RS12625	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EQH49_RS12630	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EQH49_RS12645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EQH49_RS12655	COG2501	S4 domain
EQH49_RS12710	COG3121	Chaperone
EQH49_RS12715	COG3188	usher protein
EQH49_RS12730	COG1560	Kdo2-lipid A biosynthetic process
EQH49_RS12740	COG3710	Transcriptional regulator
EQH49_RS12745	COG0531	amino acid
EQH49_RS12750	COG1982	Orn Lys Arg decarboxylase major
EQH49_RS12755	COG3104	oligopeptide transport
EQH49_RS12785	COG0673	inositol 2-dehydrogenase activity
EQH49_RS12800	COG1129	ABC transporter
EQH49_RS12805	COG4211	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS12850	COG1566	PFAM secretion protein HlyD family protein
EQH49_RS12855	COG1120	ATPase activity
EQH49_RS12860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQH49_RS12880	COG1473	amidohydrolase
EQH49_RS12885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQH49_RS12890	COG0667	Aldo Keto reductase
EQH49_RS12935	COG0531	amino acid
EQH49_RS12945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EQH49_RS12950	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS12965	COG1113	amino acid transport
EQH49_RS12970	COG2211	Major facilitator Superfamily
EQH49_RS12980	COG0673	inositol 2-dehydrogenase activity
EQH49_RS12995	COG0668	transmembrane transport
EQH49_RS13000	COG0477	Major facilitator Superfamily
EQH49_RS13015	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EQH49_RS13015	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EQH49_RS13020	COG2222	sugar isomerase
EQH49_RS13025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EQH49_RS13030	COG3716	PTS system mannose fructose sorbose family IID component
EQH49_RS13040	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQH49_RS13050	COG0778	Nitroreductase
EQH49_RS13055	COG2315	Protein conserved in bacteria
EQH49_RS13100	COG3698	Phosphodiester glycosidase
EQH49_RS13110	COG4166	transmembrane transport
EQH49_RS13120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQH49_RS13125	COG4608	Belongs to the ABC transporter superfamily
EQH49_RS13140	COG0697	spore germination
EQH49_RS13155	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EQH49_RS13165	COG4215	(ABC) transporter
EQH49_RS13175	COG4221	oxidoreductase activity
EQH49_RS13180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EQH49_RS13190	COG4608	Belongs to the ABC transporter superfamily
EQH49_RS13195	COG0444	Belongs to the ABC transporter superfamily
EQH49_RS13200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQH49_RS13205	COG0601	transmembrane transport
EQH49_RS13210	COG0747	negative chemotaxis
EQH49_RS13235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EQH49_RS13245	COG0668	transmembrane transport
EQH49_RS13250	COG0583	DNA-binding transcription factor activity
EQH49_RS13260	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS13270	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS13275	COG1129	ABC transporter
EQH49_RS13285	COG1879	ABC-type sugar transport system periplasmic component
EQH49_RS13290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EQH49_RS13295	COG2390	Transcriptional regulator
EQH49_RS13300	COG3959	Transketolase, thiamine diphosphate binding domain
EQH49_RS13305	COG3958	Transketolase
EQH49_RS13310	COG2977	Belongs to the P-Pant transferase superfamily
EQH49_RS13315	COG4771	TonB-dependent receptor
EQH49_RS13320	COG2382	esterase
EQH49_RS13325	COG3251	PFAM MbtH domain protein
EQH49_RS13330	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EQH49_RS13330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQH49_RS13335	COG1120	ATPase activity
EQH49_RS13340	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQH49_RS13345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQH49_RS13355	COG4592	Periplasmic binding protein
EQH49_RS13360	COG1169	isochorismate synthase
EQH49_RS13365	COG1021	2,3-dihydroxybenzoate-AMP ligase
EQH49_RS13370	COG1535	isochorismatase
EQH49_RS13370	COG3433	isochorismatase activity
EQH49_RS13375	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS13385	COG1966	Carbon starvation protein
EQH49_RS13390	COG2879	small protein
EQH49_RS13405	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS13410	COG0371	Dehydrogenase
EQH49_RS13415	COG1129	ABC transporter
EQH49_RS13420	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS13455	COG2271	Major facilitator Superfamily
EQH49_RS13460	COG0483	inositol monophosphate 1-phosphatase activity
EQH49_RS13470	COG0402	S-adenosylhomocysteine deaminase activity
EQH49_RS13480	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EQH49_RS13495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EQH49_RS13505	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS13510	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS13515	COG1129	ABC transporter
EQH49_RS13540	COG0436	Aminotransferase
EQH49_RS13545	COG1475	DNA binding
EQH49_RS13550	COG3969	phosphoadenosine phosphosulfate
EQH49_RS13555	COG0583	DNA-binding transcription factor activity
EQH49_RS13560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EQH49_RS13580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EQH49_RS13585	COG3719	Belongs to the RNase T2 family
EQH49_RS13590	COG3069	C4-dicarboxylate transmembrane transporter activity
EQH49_RS13610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EQH49_RS13625	COG0583	DNA-binding transcription factor activity
EQH49_RS13640	COG1686	Belongs to the peptidase S11 family
EQH49_RS13645	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EQH49_RS13650	COG0772	Belongs to the SEDS family
EQH49_RS13655	COG0768	penicillin binding
EQH49_RS13665	COG0799	negative regulation of ribosome biogenesis
EQH49_RS13680	COG1466	dna polymerase III delta subunit
EQH49_RS13695	COG2888	peptidyl-tyrosine sulfation
EQH49_RS13710	COG1126	abc transporter atp-binding protein
EQH49_RS13715	COG0765	amino acid transport
EQH49_RS13720	COG0765	amino acid transport
EQH49_RS13745	COG1702	phosphate starvation-inducible protein PhoH
EQH49_RS13755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EQH49_RS13800	COG0367	asparagine synthase
EQH49_RS13805	COG0647	UMP catabolic process
EQH49_RS13810	COG1846	Transcriptional regulator
EQH49_RS13810	COG1940	carbohydrate kinase activity
EQH49_RS13815	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EQH49_RS13855	COG0735	belongs to the Fur family
EQH49_RS13870	COG0596	Alpha beta hydrolase
EQH49_RS13880	COG0033	Phosphoglucomutase
EQH49_RS13890	COG0745	RESPONSE REGULATOR receiver
EQH49_RS13895	COG2205	protein histidine kinase activity
EQH49_RS13925	COG0415	Belongs to the DNA photolyase family
EQH49_RS13940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EQH49_RS13945	COG1984	allophanate hydrolase subunit 2
EQH49_RS13980	COG2009	succinate dehydrogenase
EQH49_RS13985	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EQH49_RS13990	COG1053	succinate dehydrogenase
EQH49_RS13995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EQH49_RS14000	COG0567	Dehydrogenase, E1 component
EQH49_RS14005	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQH49_RS14015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EQH49_RS14025	COG1271	oxidase subunit
EQH49_RS14030	COG1294	oxidase, subunit
EQH49_RS14035	COG4890	Cyd operon protein YbgT
EQH49_RS14040	COG3790	cyd operon protein YbgE
EQH49_RS14045	COG0824	Thioesterase
EQH49_RS14050	COG0811	peptide transport
EQH49_RS14055	COG0848	biopolymer transport protein
EQH49_RS14060	COG3064	Membrane
EQH49_RS14070	COG2885	chlorophyll binding
EQH49_RS14075	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EQH49_RS14115	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EQH49_RS14120	COG3201	nicotinamide mononucleotide transporter
EQH49_RS14135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EQH49_RS14145	COG2017	converts alpha-aldose to the beta-anomer
EQH49_RS14155	COG1085	galactose-1-phosphate uridylyltransferase
EQH49_RS14165	COG1119	ATPase activity
EQH49_RS14170	COG3585	molybdate ion transport
EQH49_RS14170	COG2005	Transcriptional regulator
EQH49_RS14180	COG0725	ABC transporter, periplasmic molybdate-binding protein
EQH49_RS14185	COG4149	molybdate abc transporter
EQH49_RS14195	COG0561	phosphatase activity
EQH49_RS14220	COG2200	EAL domain
EQH49_RS14225	COG0789	Transcriptional regulator
EQH49_RS14255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQH49_RS14260	COG0589	response to stress
EQH49_RS14270	COG4677	pectinesterase activity
EQH49_RS14305	COG1881	PFAM PEBP family protein
EQH49_RS14310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EQH49_RS14325	COG2226	methyltransferase
EQH49_RS14360	COG0642	Histidine kinase
EQH49_RS14365	COG0745	RESPONSE REGULATOR receiver
EQH49_RS14390	COG0521	Mo-molybdopterin cofactor biosynthetic process
EQH49_RS14400	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EQH49_RS14405	COG0314	molybdopterin synthase activity
EQH49_RS14410	COG0670	Belongs to the BI1 family
EQH49_RS14415	COG0392	lysyltransferase activity
EQH49_RS14420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EQH49_RS14425	COG3568	Endonuclease Exonuclease Phosphatase
EQH49_RS14435	COG0842	Transport permease protein
EQH49_RS14440	COG0842	Transport permease protein
EQH49_RS14445	COG1131	(ABC) transporter
EQH49_RS14450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQH49_RS14455	COG1309	transcriptional regulator
EQH49_RS14460	COG0583	DNA-binding transcription factor activity
EQH49_RS14465	COG2271	Major facilitator Superfamily
EQH49_RS14470	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS14475	COG3959	Transketolase, thiamine diphosphate binding domain
EQH49_RS14480	COG3958	Transketolase
EQH49_RS14485	COG0513	Belongs to the DEAD box helicase family
EQH49_RS14490	COG1199	ATP-dependent helicase activity
EQH49_RS14495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EQH49_RS14505	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EQH49_RS14515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EQH49_RS14525	COG0668	transmembrane transport
EQH49_RS14530	COG1126	abc transporter atp-binding protein
EQH49_RS14535	COG0765	amino acid transport
EQH49_RS14540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQH49_RS14555	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EQH49_RS14560	COG2194	sulfuric ester hydrolase activity
EQH49_RS14575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EQH49_RS14580	COG2723	6-phospho-beta-galactosidase activity
EQH49_RS14585	COG2188	Transcriptional regulator
EQH49_RS14590	COG1376	ErfK ybiS ycfS ynhG family protein
EQH49_RS14595	COG2365	Tyrosine phosphatase family
EQH49_RS14600	COG0488	(ABC) transporter
EQH49_RS14610	COG2271	Major facilitator Superfamily
EQH49_RS14615	COG1609	Transcriptional regulator
EQH49_RS14625	COG0561	phosphatase activity
EQH49_RS14630	COG1882	Formate acetyltransferase
EQH49_RS14635	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EQH49_RS14640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EQH49_RS14645	COG0303	'Molybdopterin
EQH49_RS14660	COG0747	negative chemotaxis
EQH49_RS14680	COG2223	nitrite transmembrane transporter activity
EQH49_RS14690	COG2133	pyrroloquinoline quinone binding
EQH49_RS14695	COG0625	glutathione transferase activity
EQH49_RS14700	COG1686	Belongs to the peptidase S11 family
EQH49_RS14705	COG1349	DNA-binding transcription factor activity
EQH49_RS14710	COG0671	phosphoesterase, PA-phosphatase related
EQH49_RS14720	COG2814	Major facilitator Superfamily
EQH49_RS14725	COG0561	phosphatase activity
EQH49_RS14730	COG0738	Major facilitator superfamily
EQH49_RS14735	COG3226	Transcriptional regulator
EQH49_RS14760	COG0778	Nitroreductase
EQH49_RS14775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EQH49_RS14780	COG3842	ATPase activity
EQH49_RS14785	COG1176	ABC-type spermidine putrescine transport system, permease component I
EQH49_RS14790	COG1177	transmembrane transport
EQH49_RS14805	COG0745	RESPONSE REGULATOR receiver
EQH49_RS14810	COG5002	protein histidine kinase activity
EQH49_RS14815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQH49_RS14820	COG4160	amino acid transport
EQH49_RS14825	COG4215	(ABC) transporter
EQH49_RS14830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQH49_RS14835	COG1126	abc transporter atp-binding protein
EQH49_RS14845	COG2203	Gaf domain
EQH49_RS14845	COG3706	GGDEF domain
EQH49_RS14845	COG5001	Diguanylate cyclase
EQH49_RS14845	COG4251	negative regulation of phosphorylation
EQH49_RS14850	COG3023	N-Acetylmuramoyl-L-alanine amidase
EQH49_RS14855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQH49_RS14860	COG0702	epimerase
EQH49_RS14865	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EQH49_RS14880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EQH49_RS14890	COG2431	L-lysine efflux transmembrane transporter activity
EQH49_RS14900	COG3593	DNA synthesis involved in DNA repair
EQH49_RS14905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQH49_RS14915	COG1278	Cold shock
EQH49_RS14925	COG0542	response to heat
EQH49_RS14940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EQH49_RS14945	COG4988	ABC transporter
EQH49_RS14950	COG0492	ferredoxin-NADP+ reductase activity
EQH49_RS14960	COG1178	ABC-type Fe3 transport system permease component
EQH49_RS14960	COG1674	ftsk spoiiie
EQH49_RS14970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EQH49_RS14980	COG0243	molybdopterin cofactor binding
EQH49_RS14985	COG0437	4 iron, 4 sulfur cluster binding
EQH49_RS14990	COG3302	dmso reductase anchor subunit
EQH49_RS15000	COG0477	Major facilitator Superfamily
EQH49_RS15005	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EQH49_RS15010	COG1882	Formate acetyltransferase
EQH49_RS15015	COG2116	formate transmembrane transporter activity
EQH49_RS15020	COG1944	ATP diphosphatase activity
EQH49_RS15025	COG2323	membrane
EQH49_RS15045	COG0539	negative regulation of cytoplasmic translation
EQH49_RS15055	COG0658	competence protein
EQH49_RS15055	COG2333	competence protein COMEC
EQH49_RS15070	COG3214	Protein conserved in bacteria
EQH49_RS15085	COG3173	Aminoglycoside phosphotransferase
EQH49_RS15090	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EQH49_RS15095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EQH49_RS15105	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EQH49_RS15115	COG2989	Protein conserved in bacteria
EQH49_RS15120	COG3108	Peptidase M15
EQH49_RS15125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQH49_RS15130	COG1448	Aminotransferase
EQH49_RS15135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EQH49_RS15145	COG1522	sequence-specific DNA binding
EQH49_RS15155	COG0814	amino acid
EQH49_RS15165	COG1473	amidohydrolase
EQH49_RS15175	COG0308	aminopeptidase N
EQH49_RS15185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQH49_RS15190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQH49_RS15195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EQH49_RS15200	COG0431	NADPH-dependent FMN reductase
EQH49_RS15215	COG3217	Mosc domain protein beta barrel domain protein
EQH49_RS15215	COG0633	Ferredoxin
EQH49_RS15225	COG0488	(ABC) transporter
EQH49_RS15230	COG2995	paraquat-inducible protein a
EQH49_RS15235	COG3008	intermembrane lipid transfer
EQH49_RS15235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EQH49_RS15240	COG3009	Protein conserved in bacteria
EQH49_RS15245	COG3130	regulation of translation
EQH49_RS15255	COG1067	ATP-dependent peptidase activity
EQH49_RS15280	COG3070	regulator of competence-specific genes
EQH49_RS15285	COG1289	transmembrane transporter activity
EQH49_RS15290	COG3304	Inner membrane component domain
EQH49_RS15295	COG0210	DNA helicase
EQH49_RS15305	COG1832	CoA-binding protein
EQH49_RS15320	COG1881	PFAM PEBP family protein
EQH49_RS15325	COG2207	Transcriptional regulator
EQH49_RS15340	COG0670	Belongs to the BI1 family
EQH49_RS15355	COG2200	EAL domain
EQH49_RS15365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EQH49_RS15370	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS15375	COG4638	Rieske (2fe-2S)
EQH49_RS15380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EQH49_RS15385	COG0473	3-isopropylmalate dehydrogenase activity
EQH49_RS15390	COG0583	DNA-binding transcription factor activity
EQH49_RS15395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EQH49_RS15400	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS15405	COG1917	Cupin 2, conserved barrel domain protein
EQH49_RS15405	COG1396	sequence-specific DNA binding
EQH49_RS15410	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EQH49_RS15415	COG0174	glutamine synthetase
EQH49_RS15425	COG0531	amino acid
EQH49_RS15440	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS15465	COG3729	General stress protein
EQH49_RS15475	COG2233	PERMEase
EQH49_RS15510	COG1309	transcriptional regulator
EQH49_RS15525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQH49_RS15535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQH49_RS15555	COG1702	phosphate starvation-inducible protein PhoH
EQH49_RS15560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EQH49_RS15575	COG1335	isochorismatase
EQH49_RS15585	COG0583	DNA-binding transcription factor activity
EQH49_RS15590	COG1309	transcriptional regulator
EQH49_RS15615	COG3381	protein complex oligomerization
EQH49_RS15650	COG5645	(Lipo)protein
EQH49_RS15665	COG1560	Kdo2-lipid A biosynthetic process
EQH49_RS15715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQH49_RS15735	COG2814	Major facilitator Superfamily
EQH49_RS15740	COG0583	DNA-binding transcription factor activity
EQH49_RS15745	COG1530	ribonuclease E activity
EQH49_RS15760	COG1399	metal-binding, possibly nucleic acid-binding protein
EQH49_RS15780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EQH49_RS15795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EQH49_RS15800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQH49_RS15805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EQH49_RS15815	COG0470	DNA polymerase III
EQH49_RS15820	COG0084	hydrolase, TatD family'
EQH49_RS15830	COG0537	adenosine 5'-monophosphoramidase activity
EQH49_RS15835	COG5633	Lipoprotein
EQH49_RS15860	COG1252	NADH dehydrogenase
EQH49_RS15865	COG3134	Outer membrane lipoprotein
EQH49_RS15875	COG1309	transcriptional regulator
EQH49_RS15885	COG1388	LysM domain
EQH49_RS15885	COG1376	ErfK ybiS ycfS ynhG family protein
EQH49_RS15890	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EQH49_RS15895	COG4591	ABC-type transport system involved in lipoprotein release permease component
EQH49_RS15905	COG4591	ABC-type transport system involved in lipoprotein release permease component
EQH49_RS15915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EQH49_RS15925	COG2390	Transcriptional regulator
EQH49_RS15940	COG3395	kinase activity
EQH49_RS15955	COG0698	ribose 5-phosphate isomerase
EQH49_RS15960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EQH49_RS15965	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EQH49_RS15970	COG0318	PFAM AMP-dependent synthetase and ligase
EQH49_RS15985	COG1177	transmembrane transport
EQH49_RS16005	COG2850	peptidyl-arginine hydroxylation
EQH49_RS16010	COG2205	protein histidine kinase activity
EQH49_RS16030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EQH49_RS16050	COG1187	pseudouridine synthase activity
EQH49_RS16055	COG0538	isocitrate dehydrogenase activity
EQH49_RS16060	COG0582	viral genome integration into host DNA
EQH49_RS16075	COG3706	GGDEF domain
EQH49_RS16080	COG5001	Diguanylate cyclase
EQH49_RS16080	COG3300	MHYT domain
EQH49_RS16090	COG0538	isocitrate dehydrogenase activity
EQH49_RS16095	COG0640	Transcriptional regulator
EQH49_RS16120	COG3813	Protein conserved in bacteria
EQH49_RS16125	COG1063	alcohol dehydrogenase
EQH49_RS16135	COG3729	General stress protein
EQH49_RS16140	COG3685	Protein conserved in bacteria
EQH49_RS16145	COG3685	Protein conserved in bacteria
EQH49_RS16150	COG3546	catalase activity
EQH49_RS16155	COG1271	oxidase subunit
EQH49_RS16160	COG1294	oxidase, subunit
EQH49_RS16185	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EQH49_RS16190	COG0583	DNA-binding transcription factor activity
EQH49_RS16195	COG3706	GGDEF domain
EQH49_RS16200	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EQH49_RS16210	COG1560	Kdo2-lipid A biosynthetic process
EQH49_RS16220	COG3182	Iron-regulated membrane protein
EQH49_RS16240	COG2199	diguanylate cyclase activity
EQH49_RS16240	COG2203	Gaf domain
EQH49_RS16245	COG3042	response to heat
EQH49_RS16250	COG3189	MarR family transcriptional regulator
EQH49_RS16255	COG1683	Conserved Protein
EQH49_RS16260	COG0504	CTP synthase activity
EQH49_RS16265	COG2807	transmembrane transport
EQH49_RS16270	COG2207	Transcriptional regulator
EQH49_RS16280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EQH49_RS16285	COG0859	PFAM glycosyl transferase family 9
EQH49_RS16295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EQH49_RS16300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQH49_RS16305	COG0583	DNA-binding transcription factor activity
EQH49_RS16310	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS16330	COG0386	Belongs to the glutathione peroxidase family
EQH49_RS16345	COG2766	serine protein kinase
EQH49_RS16350	COG3713	MltA-interacting MipA family protein
EQH49_RS16355	COG0656	L-ascorbic acid biosynthetic process
EQH49_RS16375	COG3139	Protein of unknown function (DUF1315)
EQH49_RS16390	COG1063	alcohol dehydrogenase
EQH49_RS16395	COG2271	Major facilitator Superfamily
EQH49_RS16400	COG1063	alcohol dehydrogenase
EQH49_RS16405	COG0191	fructose-bisphosphate aldolase activity
EQH49_RS16410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQH49_RS16415	COG0667	Aldo Keto reductase
EQH49_RS16420	COG1349	DNA-binding transcription factor activity
EQH49_RS16425	COG2814	Major facilitator Superfamily
EQH49_RS16430	COG1335	isochorismatase
EQH49_RS16435	COG0252	asparaginase activity
EQH49_RS16440	COG0616	signal peptide processing
EQH49_RS16445	COG0778	Nitroreductase
EQH49_RS16455	COG0709	Synthesizes selenophosphate from selenide and ATP
EQH49_RS16460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQH49_RS16465	COG3321	synthase
EQH49_RS16465	COG0604	alcohol dehydrogenase
EQH49_RS16465	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS16470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EQH49_RS16475	COG0494	nUDIX hydrolase
EQH49_RS16480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EQH49_RS16485	COG2897	thiosulfate sulfurtransferase activity
EQH49_RS16490	COG4136	ATPase activity
EQH49_RS16495	COG4135	transport system, permease component
EQH49_RS16500	COG4134	Bacterial extracellular solute-binding protein
EQH49_RS16505	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQH49_RS16510	COG0398	Pfam SNARE associated Golgi protein
EQH49_RS16515	COG0398	Pfam SNARE associated Golgi protein
EQH49_RS16520	COG0708	Exodeoxyribonuclease III
EQH49_RS16530	COG3138	arginine N-succinyltransferase
EQH49_RS16540	COG3724	N-succinylarginine dihydrolase activity
EQH49_RS16550	COG3678	ATP-independent chaperone mediated protein folding
EQH49_RS16555	COG0322	excinuclease ABC activity
EQH49_RS16565	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EQH49_RS16570	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQH49_RS16575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQH49_RS16580	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQH49_RS16585	COG1917	Cupin 2, conserved barrel domain protein
EQH49_RS16585	COG2169	Transcriptional regulator
EQH49_RS16590	COG1486	melibiose metabolic process
EQH49_RS16600	COG0753	catalase activity
EQH49_RS16610	COG1823	symporter activity
EQH49_RS16615	COG1988	membrane-bound metal-dependent
EQH49_RS16620	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS16625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQH49_RS16655	COG0727	PFAM Uncharacterised protein family (UPF0153)
EQH49_RS16660	COG3047	cAMP biosynthetic process
EQH49_RS16675	COG0582	viral genome integration into host DNA
EQH49_RS16705	COG4774	siderophore transport
EQH49_RS16760	COG0135	phosphoribosylanthranilate isomerase activity
EQH49_RS16760	COG0134	indole-3-glycerol-phosphate synthase activity
EQH49_RS16765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EQH49_RS16765	COG0512	Glutamine amidotransferase of anthranilate synthase
EQH49_RS16770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EQH49_RS16780	COG0009	L-threonylcarbamoyladenylate synthase
EQH49_RS16790	COG0583	DNA-binding transcription factor activity
EQH49_RS16800	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EQH49_RS16805	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS16815	COG0616	signal peptide processing
EQH49_RS16840	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EQH49_RS16850	COG0671	phosphoesterase, PA-phosphatase related
EQH49_RS16855	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EQH49_RS16860	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EQH49_RS16870	COG0023	Translation Initiation Factor
EQH49_RS16880	COG1349	DNA-binding transcription factor activity
EQH49_RS16895	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQH49_RS16895	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQH49_RS16900	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EQH49_RS16910	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EQH49_RS16925	COG4171	peptide transport system, permease
EQH49_RS16960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EQH49_RS17020	COG1846	Transcriptional regulator
EQH49_RS17100	COG0484	heat shock protein binding
EQH49_RS17190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EQH49_RS17195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQH49_RS17205	COG2135	peptidase activity
EQH49_RS17220	COG0702	epimerase
EQH49_RS17235	COG1473	amidohydrolase
EQH49_RS17245	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EQH49_RS17250	COG1842	Phage shock protein A
EQH49_RS17260	COG1983	PspC domain protein
EQH49_RS17270	COG3106	COG3106 Predicted ATPase
EQH49_RS17280	COG0583	DNA-binding transcription factor activity
EQH49_RS17285	COG1486	melibiose metabolic process
EQH49_RS17295	COG3180	Ammonia monooxygenase
EQH49_RS17300	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EQH49_RS17305	COG4948	Mandelate Racemase Muconate Lactonizing
EQH49_RS17310	COG2866	Carboxypeptidase
EQH49_RS17315	COG4166	transmembrane transport
EQH49_RS17345	COG0656	L-ascorbic acid biosynthetic process
EQH49_RS17365	COG0583	DNA-binding transcription factor activity
EQH49_RS17370	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS17375	COG1078	dGTPase activity
EQH49_RS17380	COG0693	protein deglycase activity
EQH49_RS17405	COG2885	chlorophyll binding
EQH49_RS17480	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS17485	COG1309	transcriptional regulator
EQH49_RS17490	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS17510	COG0583	DNA-binding transcription factor activity
EQH49_RS17535	COG0604	alcohol dehydrogenase
EQH49_RS17540	COG0436	Aminotransferase
EQH49_RS17555	COG2011	ABC-type metal ion transport system permease component
EQH49_RS17570	COG1522	sequence-specific DNA binding
EQH49_RS17575	COG1113	amino acid transport
EQH49_RS17590	COG0673	inositol 2-dehydrogenase activity
EQH49_RS17595	COG1349	DNA-binding transcription factor activity
EQH49_RS17605	COG0513	Belongs to the DEAD box helicase family
EQH49_RS17615	COG0589	response to stress
EQH49_RS17625	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EQH49_RS17630	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EQH49_RS17630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EQH49_RS17630	COG1013	pyruvate-flavodoxin oxidoreductase activity
EQH49_RS17630	COG0674	pyruvate-flavodoxin oxidoreductase activity
EQH49_RS17640	COG3042	response to heat
EQH49_RS17645	COG3187	Heat shock protein
EQH49_RS17650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQH49_RS17655	COG0586	Pfam SNARE associated Golgi protein
EQH49_RS17660	COG2911	Protein conserved in bacteria
EQH49_RS17670	COG3784	Protein of unknown function (DUF1318)
EQH49_RS17675	COG2207	Transcriptional regulator
EQH49_RS17680	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS17695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQH49_RS17705	COG1126	abc transporter atp-binding protein
EQH49_RS17715	COG0583	DNA-binding transcription factor activity
EQH49_RS17720	COG2072	flavoprotein involved in K transport
EQH49_RS17735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQH49_RS17755	COG2030	dehydratase
EQH49_RS17755	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS17760	COG3396	Phenylacetate-CoA oxygenase
EQH49_RS17765	COG3460	Phenylacetate-CoA oxygenase
EQH49_RS17770	COG3396	Phenylacetate-CoA oxygenase
EQH49_RS17775	COG2151	metal-sulfur cluster biosynthetic enzyme
EQH49_RS17780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EQH49_RS17785	COG1024	Enoyl-CoA hydratase
EQH49_RS17790	COG1024	Enoyl-CoA hydratase
EQH49_RS17795	COG1250	3-hydroxyacyl-CoA dehydrogenase
EQH49_RS17800	COG2050	protein possibly involved in aromatic compounds catabolism
EQH49_RS17805	COG0183	Belongs to the thiolase family
EQH49_RS17810	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EQH49_RS17815	COG3327	negative regulation of DNA-templated transcription, initiation
EQH49_RS17820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EQH49_RS17835	COG1643	Atp-dependent helicase
EQH49_RS17840	COG4122	O-methyltransferase activity
EQH49_RS17865	COG0583	DNA-binding transcription factor activity
EQH49_RS17870	COG0667	Aldo Keto reductase
EQH49_RS17875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EQH49_RS17880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EQH49_RS17885	COG3138	arginine N-succinyltransferase
EQH49_RS17890	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS17895	COG3724	N-succinylarginine dihydrolase activity
EQH49_RS17900	COG2988	succinylglutamate desuccinylase activity
EQH49_RS17905	COG1113	amino acid transport
EQH49_RS17910	COG0477	Major facilitator Superfamily
EQH49_RS17915	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EQH49_RS17920	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS17925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EQH49_RS17930	COG0401	homolog of Blt101
EQH49_RS17935	COG5562	phage envelope protein
EQH49_RS17940	COG0425	Belongs to the sulfur carrier protein TusA family
EQH49_RS17945	COG2391	methyltransferase activity
EQH49_RS17970	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EQH49_RS17975	COG1263	PTS System
EQH49_RS17975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQH49_RS17980	COG1609	Transcriptional regulator
EQH49_RS17985	COG5339	Protein conserved in bacteria
EQH49_RS17990	COG1482	cell wall glycoprotein biosynthetic process
EQH49_RS17995	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EQH49_RS17995	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EQH49_RS18000	COG0114	fumarate hydratase activity
EQH49_RS18010	COG2205	protein histidine kinase activity
EQH49_RS18020	COG0745	RESPONSE REGULATOR receiver
EQH49_RS18025	COG3136	membrane protein required for alginate biosynthesis
EQH49_RS18035	COG0531	amino acid
EQH49_RS18055	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EQH49_RS18060	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EQH49_RS18075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EQH49_RS18090	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EQH49_RS18095	COG1473	amidohydrolase
EQH49_RS18105	COG0583	DNA-binding transcription factor activity
EQH49_RS18110	COG2840	Smr protein MutS2
EQH49_RS18115	COG1414	Transcriptional regulator
EQH49_RS18125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EQH49_RS18130	COG0183	Belongs to the thiolase family
EQH49_RS18140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EQH49_RS18145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQH49_RS18155	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EQH49_RS18155	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EQH49_RS18175	COG4565	transcriptional regulatory protein
EQH49_RS18180	COG3290	protein histidine kinase activity
EQH49_RS18220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EQH49_RS18230	COG0679	Auxin Efflux Carrier
EQH49_RS18260	COG0628	permease
EQH49_RS18280	COG3591	Belongs to the peptidase S1B family
EQH49_RS18290	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EQH49_RS18295	COG2814	Major facilitator Superfamily
EQH49_RS18300	COG0583	DNA-binding transcription factor activity
EQH49_RS18305	COG1940	carbohydrate kinase activity
EQH49_RS18310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EQH49_RS18325	COG3302	dmso reductase anchor subunit
EQH49_RS18330	COG0437	4 iron, 4 sulfur cluster binding
EQH49_RS18335	COG0243	molybdopterin cofactor binding
EQH49_RS18350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQH49_RS18365	COG2271	Major facilitator Superfamily
EQH49_RS18370	COG0246	Mannitol dehydrogenase
EQH49_RS18375	COG0589	response to stress
EQH49_RS18380	COG1802	Transcriptional regulator
EQH49_RS18385	COG4221	oxidoreductase activity
EQH49_RS18400	COG2207	Transcriptional regulator
EQH49_RS18405	COG2135	peptidase activity
EQH49_RS18430	COG0071	Belongs to the small heat shock protein (HSP20) family
EQH49_RS18435	COG1546	Belongs to the CinA family
EQH49_RS18440	COG2200	EAL domain
EQH49_RS18460	COG3708	Transcriptional regulator
EQH49_RS18460	COG2207	Transcriptional regulator
EQH49_RS18465	COG2610	gluconate transmembrane transporter activity
EQH49_RS18470	COG3622	Belongs to the hyi family
EQH49_RS18475	COG0235	Class ii aldolase
EQH49_RS18480	COG3395	kinase activity
EQH49_RS18485	COG2084	Dehydrogenase
EQH49_RS18490	COG1349	DNA-binding transcription factor activity
EQH49_RS18505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EQH49_RS18510	COG2223	nitrite transmembrane transporter activity
EQH49_RS18545	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQH49_RS18550	COG0683	leucine binding
EQH49_RS18580	COG2814	Major facilitator Superfamily
EQH49_RS18585	COG0697	spore germination
EQH49_RS18595	COG4977	sequence-specific DNA binding
EQH49_RS18620	COG2271	Major facilitator Superfamily
EQH49_RS18625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EQH49_RS18630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQH49_RS18640	COG3395	kinase activity
EQH49_RS18645	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EQH49_RS18650	COG1349	DNA-binding transcription factor activity
EQH49_RS18665	COG0583	DNA-binding transcription factor activity
EQH49_RS18670	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS18685	COG2199	diguanylate cyclase activity
EQH49_RS18755	COG0477	Major facilitator Superfamily
EQH49_RS18765	COG2070	2-Nitropropane dioxygenase
EQH49_RS18770	COG2011	ABC-type metal ion transport system permease component
EQH49_RS18790	COG4628	conserved protein (DUF2132)
EQH49_RS18805	COG2207	Transcriptional regulator
EQH49_RS18835	COG2233	PERMEase
EQH49_RS18840	COG3195	allantoin biosynthetic process
EQH49_RS18840	COG3648	Uricase
EQH49_RS18845	COG2351	hydroxyisourate hydrolase activity
EQH49_RS18850	COG1396	sequence-specific DNA binding
EQH49_RS18855	COG3550	peptidyl-serine autophosphorylation
EQH49_RS18860	COG1649	PFAM Uncharacterised BCR, COG1649
EQH49_RS18875	COG3188	usher protein
EQH49_RS18910	COG3300	MHYT domain
EQH49_RS18910	COG5001	Diguanylate cyclase
EQH49_RS18915	COG2819	hydrolase of the alpha beta superfamily
EQH49_RS18925	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS18925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS18930	COG2814	Major facilitator Superfamily
EQH49_RS18940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQH49_RS18940	COG1263	PTS System
EQH49_RS18945	COG2186	Transcriptional regulator
EQH49_RS18965	COG3835	regulator
EQH49_RS18970	COG1929	Belongs to the glycerate kinase type-1 family
EQH49_RS19015	COG0738	Major facilitator superfamily
EQH49_RS19020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQH49_RS19025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EQH49_RS19030	COG1349	DNA-binding transcription factor activity
EQH49_RS19050	COG4977	sequence-specific DNA binding
EQH49_RS19070	COG4977	sequence-specific DNA binding
EQH49_RS19090	COG0456	acetyltransferase
EQH49_RS19090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EQH49_RS19115	COG1652	LysM domain
EQH49_RS19125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQH49_RS19125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQH49_RS19125	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EQH49_RS19130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQH49_RS19140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EQH49_RS19145	COG3037	sugar-specific permease SgaT UlaA
EQH49_RS19155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS19160	COG1609	Transcriptional regulator
EQH49_RS19170	COG2223	nitrite transmembrane transporter activity
EQH49_RS19200	COG0477	Major facilitator Superfamily
EQH49_RS19205	COG4529	Protein conserved in bacteria
EQH49_RS19210	COG1902	pentaerythritol trinitrate reductase activity
EQH49_RS19220	COG0583	DNA-binding transcription factor activity
EQH49_RS19225	COG2070	2-Nitropropane dioxygenase
EQH49_RS19235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EQH49_RS19245	COG0765	amino acid transport
EQH49_RS19290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EQH49_RS19310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EQH49_RS19330	COG2207	Transcriptional regulator
EQH49_RS19365	COG1335	isochorismatase
EQH49_RS19375	COG0406	alpha-ribazole phosphatase activity
EQH49_RS19410	COG1953	Uracil, thiamine, allantoin
EQH49_RS19415	COG0402	S-adenosylhomocysteine deaminase activity
EQH49_RS19420	COG3706	GGDEF domain
EQH49_RS19425	COG1609	Transcriptional regulator
EQH49_RS19435	COG0673	inositol 2-dehydrogenase activity
EQH49_RS19445	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EQH49_RS19450	COG1116	anion transmembrane transporter activity
EQH49_RS19455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQH49_RS19460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EQH49_RS19465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EQH49_RS19470	COG0076	glutamate decarboxylase activity
EQH49_RS19490	COG2205	protein histidine kinase activity
EQH49_RS19500	COG0596	Alpha beta hydrolase
EQH49_RS19540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EQH49_RS19540	COG0519	Catalyzes the synthesis of GMP from XMP
EQH49_RS19560	COG0583	DNA-binding transcription factor activity
EQH49_RS19570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EQH49_RS19575	COG1285	pathogenesis
EQH49_RS19585	COG2814	Major facilitator Superfamily
EQH49_RS19590	COG0583	DNA-binding transcription factor activity
EQH49_RS19595	COG0243	molybdopterin cofactor binding
EQH49_RS19600	COG3781	membrane
EQH49_RS19625	COG1764	response to oxidative stress
EQH49_RS19630	COG3111	PFAM Bacterial OB fold (BOF) protein
EQH49_RS19640	COG2323	membrane
EQH49_RS19650	COG0366	Alpha amylase catalytic
EQH49_RS19660	COG3685	Protein conserved in bacteria
EQH49_RS19680	COG3729	General stress protein
EQH49_RS19685	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS19725	COG0488	(ABC) transporter
EQH49_RS19740	COG1064	alcohol dehydrogenase
EQH49_RS19745	COG0747	negative chemotaxis
EQH49_RS19755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQH49_RS19765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQH49_RS19775	COG2814	Major facilitator Superfamily
EQH49_RS19785	COG2326	polyphosphate kinase activity
EQH49_RS19800	COG2864	formate dehydrogenase
EQH49_RS19805	COG0437	4 iron, 4 sulfur cluster binding
EQH49_RS19830	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EQH49_RS19840	COG3485	protocatechuate 3,4-dioxygenase
EQH49_RS19845	COG4829	muconolactone delta-isomerase
EQH49_RS19850	COG4948	Mandelate Racemase Muconate Lactonizing
EQH49_RS19855	COG1414	Transcriptional regulator
EQH49_RS19875	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EQH49_RS19880	COG1140	nitrate reductase beta subunit
EQH49_RS19885	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EQH49_RS19890	COG2181	nitrate reductase activity
EQH49_RS19895	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EQH49_RS19900	COG1178	ABC-type Fe3 transport system permease component
EQH49_RS19905	COG1840	ABC-type Fe3 transport system, periplasmic component
EQH49_RS19910	COG3842	ATPase activity
EQH49_RS19915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EQH49_RS19930	COG2211	Major facilitator Superfamily
EQH49_RS19955	COG0625	glutathione transferase activity
EQH49_RS19965	COG1126	abc transporter atp-binding protein
EQH49_RS19970	COG0765	amino acid transport
EQH49_RS19980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQH49_RS19985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQH49_RS19990	COG1473	amidohydrolase
EQH49_RS19995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQH49_RS20000	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EQH49_RS20025	COG4772	TonB-dependent receptor
EQH49_RS20030	COG1228	amidohydrolase
EQH49_RS20035	COG3691	Protein conserved in bacteria
EQH49_RS20045	COG2130	NADP-dependent
EQH49_RS20055	COG1247	-acetyltransferase
EQH49_RS20060	COG3238	Protein conserved in bacteria
EQH49_RS20070	COG0747	negative chemotaxis
EQH49_RS20075	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS20105	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS20110	COG1177	transmembrane transport
EQH49_RS20115	COG1176	ABC-type spermidine putrescine transport system, permease component I
EQH49_RS20120	COG3842	ATPase activity
EQH49_RS20125	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EQH49_RS20130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQH49_RS20135	COG1271	oxidase subunit
EQH49_RS20140	COG1294	oxidase, subunit
EQH49_RS20160	COG0826	peptidase U32
EQH49_RS20170	COG1396	sequence-specific DNA binding
EQH49_RS20175	COG3135	benzoate transporter
EQH49_RS20180	COG3708	Transcriptional regulator
EQH49_RS20180	COG2207	Transcriptional regulator
EQH49_RS20195	COG0500	methyltransferase
EQH49_RS20200	COG1275	C4-dicarboxylate transporter malic acid transport protein
EQH49_RS20205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EQH49_RS20210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQH49_RS20225	COG2272	Belongs to the type-B carboxylesterase lipase family
EQH49_RS20230	COG5383	Protein conserved in bacteria
EQH49_RS20235	COG3485	protocatechuate 3,4-dioxygenase
EQH49_RS20240	COG3485	protocatechuate 3,4-dioxygenase
EQH49_RS20245	COG0583	DNA-binding transcription factor activity
EQH49_RS20265	COG3038	cytochrome b561
EQH49_RS20285	COG2814	Major facilitator Superfamily
EQH49_RS20295	COG0673	inositol 2-dehydrogenase activity
EQH49_RS20305	COG2723	6-phospho-beta-galactosidase activity
EQH49_RS20340	COG4659	FMN binding
EQH49_RS20350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EQH49_RS20365	COG0625	glutathione transferase activity
EQH49_RS20370	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EQH49_RS20385	COG3895	Periplasmic Protein
EQH49_RS20400	COG3706	GGDEF domain
EQH49_RS20415	COG1566	PFAM secretion protein HlyD family protein
EQH49_RS20420	COG1289	transmembrane transporter activity
EQH49_RS20425	COG2032	superoxide dismutase activity
EQH49_RS20430	COG4989	oxidoreductase activity
EQH49_RS20435	COG3313	Fe-S protein
EQH49_RS20440	COG1309	transcriptional regulator
EQH49_RS20445	COG1902	pentaerythritol trinitrate reductase activity
EQH49_RS20450	COG0346	lactoylglutathione lyase activity
EQH49_RS20460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EQH49_RS20465	COG0791	NLP P60 protein
EQH49_RS20480	COG2814	Major facilitator Superfamily
EQH49_RS20495	COG0583	DNA-binding transcription factor activity
EQH49_RS20500	COG2814	Major facilitator Superfamily
EQH49_RS20505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EQH49_RS20510	COG0307	riboflavin synthase, alpha
EQH49_RS20585	COG3179	chitinase
EQH49_RS20615	COG0300	oxidoreductase activity
EQH49_RS20635	COG1234	tRNA 3'-trailer cleavage
EQH49_RS20665	COG1349	DNA-binding transcription factor activity
EQH49_RS20670	COG0346	lactoylglutathione lyase activity
EQH49_RS20695	COG0444	Belongs to the ABC transporter superfamily
EQH49_RS20700	COG4608	Belongs to the ABC transporter superfamily
EQH49_RS20725	COG0583	DNA-binding transcription factor activity
EQH49_RS20730	COG0531	amino acid
EQH49_RS20735	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS20745	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EQH49_RS20780	COG0402	S-adenosylhomocysteine deaminase activity
EQH49_RS20805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQH49_RS20810	COG0277	FAD linked oxidase domain protein
EQH49_RS20830	COG0583	DNA-binding transcription factor activity
EQH49_RS20840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EQH49_RS20850	COG1250	3-hydroxyacyl-CoA dehydrogenase
EQH49_RS20855	COG2610	gluconate transmembrane transporter activity
EQH49_RS20860	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS20905	COG4235	cytochrome complex assembly
EQH49_RS20905	COG3088	subunit of a heme lyase
EQH49_RS20910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQH49_RS20915	COG1138	Cytochrome C-type biogenesis protein
EQH49_RS20930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EQH49_RS20935	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EQH49_RS20940	COG4133	protoheme IX ABC transporter activity
EQH49_RS20970	COG1175	transmembrane transport
EQH49_RS20985	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EQH49_RS20990	COG3383	formate dehydrogenase (NAD+) activity
EQH49_RS20995	COG1473	amidohydrolase
EQH49_RS21025	COG1126	abc transporter atp-binding protein
EQH49_RS21050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQH49_RS21055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQH49_RS21060	COG1120	ATPase activity
EQH49_RS21065	COG4774	siderophore transport
EQH49_RS21070	COG1116	anion transmembrane transporter activity
EQH49_RS21075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQH49_RS21095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQH49_RS21100	COG0583	DNA-binding transcription factor activity
EQH49_RS21120	COG2814	Major facilitator Superfamily
EQH49_RS21155	COG1414	Transcriptional regulator
EQH49_RS21160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQH49_RS21165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQH49_RS21170	COG1120	ATPase activity
EQH49_RS21180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EQH49_RS21185	COG2271	Major facilitator Superfamily
EQH49_RS21190	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EQH49_RS21190	COG1082	Xylose isomerase domain protein TIM barrel
EQH49_RS21195	COG1309	transcriptional regulator
EQH49_RS21220	COG1376	ErfK ybiS ycfS ynhG family protein
EQH49_RS21235	COG0719	Fe-S assembly protein
EQH49_RS21240	COG0396	ATPase activity
EQH49_RS21245	COG0719	Fe-S assembly protein
EQH49_RS21250	COG0316	Belongs to the HesB IscA family
EQH49_RS21265	COG1309	transcriptional regulator
EQH49_RS21270	COG1304	FMN binding
EQH49_RS21295	COG0583	DNA-binding transcription factor activity
EQH49_RS21305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQH49_RS21310	COG1120	ATPase activity
EQH49_RS21340	COG2261	transglycosylase associated protein
EQH49_RS21345	COG2050	protein possibly involved in aromatic compounds catabolism
EQH49_RS21350	COG0247	lactate metabolic process
EQH49_RS21350	COG0277	FAD linked oxidase domain protein
EQH49_RS21355	COG0628	permease
EQH49_RS21365	COG0574	Belongs to the PEP-utilizing enzyme family
EQH49_RS21365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EQH49_RS21375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EQH49_RS21380	COG4256	Hemin uptake protein
EQH49_RS21390	COG0791	NLP P60 protein
EQH49_RS21400	COG0386	Belongs to the glutathione peroxidase family
EQH49_RS21420	COG0583	DNA-binding transcription factor activity
EQH49_RS21440	COG0072	phenylalanine-tRNA ligase activity
EQH49_RS21440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQH49_RS21480	COG3137	Salt-induced outer membrane protein
EQH49_RS21485	COG1105	Belongs to the carbohydrate kinase PfkB family
EQH49_RS21495	COG3001	Fructosamine kinase
EQH49_RS21505	COG2350	Protein conserved in bacteria
EQH49_RS21510	COG2353	YceI-like domain
EQH49_RS21530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EQH49_RS21540	COG0444	Belongs to the ABC transporter superfamily
EQH49_RS21545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQH49_RS21550	COG0601	transmembrane transport
EQH49_RS21555	COG4166	transmembrane transport
EQH49_RS21560	COG2095	MarC family integral membrane protein
EQH49_RS21570	COG1012	belongs to the aldehyde dehydrogenase family
EQH49_RS21570	COG1454	alcohol dehydrogenase
EQH49_RS21575	COG1435	thymidine kinase activity
EQH49_RS21580	COG2916	Histone family protein nucleoid-structuring protein H-NS
EQH49_RS21585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EQH49_RS21590	COG0745	RESPONSE REGULATOR receiver
EQH49_RS21595	COG1752	Esterase of the alpha-beta hydrolase superfamily
EQH49_RS21605	COG0788	formyltetrahydrofolate deformylase activity
EQH49_RS21645	COG1522	sequence-specific DNA binding
EQH49_RS21655	COG2181	nitrate reductase activity
EQH49_RS21660	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EQH49_RS21665	COG1140	nitrate reductase beta subunit
EQH49_RS21670	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EQH49_RS21675	COG2223	nitrite transmembrane transporter activity
EQH49_RS21680	COG3850	Histidine kinase
EQH49_RS21685	COG2197	response regulator
EQH49_RS21690	COG4932	domain protein
EQH49_RS21695	COG0243	molybdopterin cofactor binding
EQH49_RS21700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQH49_RS21700	COG2146	nitrite reductase [NAD(P)H] activity
EQH49_RS21705	COG1116	anion transmembrane transporter activity
EQH49_RS21715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EQH49_RS21720	COG3707	response regulator
EQH49_RS21725	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EQH49_RS21735	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EQH49_RS21740	COG4572	Cation transport regulator
EQH49_RS21745	COG0387	Pfam Sodium calcium exchanger
EQH49_RS21765	COG2890	protein-(glutamine-N5) methyltransferase activity
EQH49_RS21795	COG0659	secondary active sulfate transmembrane transporter activity
EQH49_RS21815	COG0012	GTP binding
EQH49_RS21880	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EQH49_RS21895	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EQH49_RS21975	COG2885	chlorophyll binding
EQH49_RS22000	COG3122	Protein conserved in bacteria
EQH49_RS22015	COG0583	DNA-binding transcription factor activity
EQH49_RS22045	COG0583	DNA-binding transcription factor activity
EQH49_RS22075	COG1882	Formate acetyltransferase
EQH49_RS22090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EQH49_RS22095	COG0583	DNA-binding transcription factor activity
EQH49_RS22135	COG2308	Evidence 4 Homologs of previously reported genes of
EQH49_RS22150	COG4774	siderophore transport
EQH49_RS22160	COG1619	proteins homologs of microcin C7 resistance protein MccF
EQH49_RS22180	COG2719	SpoVR family
EQH49_RS22210	COG0179	Fumarylacetoacetate (FAA) hydrolase
EQH49_RS22225	COG2894	cell division
EQH49_RS22235	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EQH49_RS22245	COG3065	identical protein binding
EQH49_RS22255	COG1199	ATP-dependent helicase activity
EQH49_RS22260	COG0251	oxidation-reduction process
EQH49_RS22280	COG1760	l-serine dehydratase
EQH49_RS22285	COG2200	EAL domain
EQH49_RS22290	COG1253	flavin adenine dinucleotide binding
EQH49_RS22295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQH49_RS22295	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS22300	COG3715	PTS system
EQH49_RS22305	COG3716	PTS system mannose fructose sorbose family IID component
EQH49_RS22320	COG2226	methyltransferase
EQH49_RS22325	COG0768	penicillin binding
EQH49_RS22365	COG1414	Transcriptional regulator
EQH49_RS22370	COG2814	Major facilitator Superfamily
EQH49_RS22390	COG1956	GAF domain-containing protein
EQH49_RS22395	COG2995	paraquat-inducible protein a
EQH49_RS22400	COG3008	intermembrane lipid transfer
EQH49_RS22425	COG2990	Protein conserved in bacteria
EQH49_RS22445	COG1276	copper resistance
EQH49_RS22450	COG2372	response to copper ion
EQH49_RS22460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EQH49_RS22465	COG1770	oligopeptidase
EQH49_RS22470	COG2979	Protein of unknown function (DUF533)
EQH49_RS22475	COG3141	response to X-ray
EQH49_RS22485	COG0800	Aldolase
EQH49_RS22490	COG0129	dihydroxy-acid dehydratase activity
EQH49_RS22495	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EQH49_RS22510	COG1737	Transcriptional regulator
EQH49_RS22520	COG1560	Kdo2-lipid A biosynthetic process
EQH49_RS22525	COG0739	heme binding
EQH49_RS22530	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EQH49_RS22540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQH49_RS22565	COG0494	nUDIX hydrolase
EQH49_RS22575	COG1335	isochorismatase
EQH49_RS22580	COG1801	Protein of unknown function DUF72
EQH49_RS22585	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EQH49_RS22605	COG3102	Protein conserved in bacteria
EQH49_RS22615	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EQH49_RS22640	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQH49_RS22650	COG1879	ABC-type sugar transport system periplasmic component
EQH49_RS22660	COG1528	Iron-storage protein
EQH49_RS22670	COG2211	Major facilitator Superfamily
EQH49_RS22680	COG0477	Major facilitator Superfamily
EQH49_RS22695	COG1528	Iron-storage protein
EQH49_RS22705	COG0814	amino acid
EQH49_RS22710	COG3012	SEC-C Motif Domain Protein
EQH49_RS22710	COG3318	Belongs to the UPF0149 family
EQH49_RS22750	COG2197	response regulator
EQH49_RS22760	COG2197	response regulator
EQH49_RS22765	COG1126	abc transporter atp-binding protein
EQH49_RS22770	COG0765	amino acid transport
EQH49_RS22780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQH49_RS22785	COG0366	Alpha amylase catalytic
EQH49_RS22815	COG2354	Protein conserved in bacteria
EQH49_RS22820	COG0697	spore germination
EQH49_RS22825	COG3727	T/G mismatch-specific endonuclease activity
EQH49_RS22830	COG0270	DNA (cytosine-5-)-methyltransferase activity
EQH49_RS22835	COG1418	mRNA catabolic process
EQH49_RS22850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EQH49_RS22870	COG0582	viral genome integration into host DNA
EQH49_RS22880	COG0183	Belongs to the thiolase family
EQH49_RS22885	COG2814	Major facilitator Superfamily
EQH49_RS22890	COG3320	Male sterility
EQH49_RS22890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQH49_RS22925	COG0583	DNA-binding transcription factor activity
EQH49_RS22930	COG1794	racemase activity, acting on amino acids and derivatives
EQH49_RS22965	COG0025	NhaP-type Na H and K H
EQH49_RS22970	COG1309	transcriptional regulator
EQH49_RS22975	COG0604	alcohol dehydrogenase
EQH49_RS22995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EQH49_RS23005	COG0534	Mate efflux family protein
EQH49_RS23015	COG0582	viral genome integration into host DNA
EQH49_RS23030	COG1737	Transcriptional regulator
EQH49_RS23045	COG2814	Major facilitator Superfamily
EQH49_RS23050	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS23065	COG4977	sequence-specific DNA binding
EQH49_RS23070	COG1566	PFAM secretion protein HlyD family protein
EQH49_RS23085	COG2207	Transcriptional regulator
EQH49_RS23110	COG3706	GGDEF domain
EQH49_RS23135	COG3615	Tellurite resistance protein tehB
EQH49_RS23145	COG5001	Diguanylate cyclase
EQH49_RS23145	COG3300	MHYT domain
EQH49_RS23160	COG0477	Major facilitator Superfamily
EQH49_RS23165	COG0095	Lipoate-protein ligase
EQH49_RS23170	COG0583	DNA-binding transcription factor activity
EQH49_RS23175	COG1942	4-Oxalocrotonate Tautomerase
EQH49_RS23185	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EQH49_RS23205	COG1289	transmembrane transporter activity
EQH49_RS23220	COG2925	Exonuclease
EQH49_RS23230	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EQH49_RS23235	COG0640	Transcriptional regulator
EQH49_RS23240	COG0531	amino acid
EQH49_RS23250	COG0583	DNA-binding transcription factor activity
EQH49_RS23255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQH49_RS23285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EQH49_RS23315	COG1216	Glycosyl transferase, family 2
EQH49_RS23315	COG1442	glycosyl transferase family 8
EQH49_RS23320	COG0438	transferase activity, transferring glycosyl groups
EQH49_RS23385	COG1088	dTDP-glucose 4,6-dehydratase activity
EQH49_RS23415	COG2244	polysaccharide biosynthetic process
EQH49_RS23430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EQH49_RS23465	COG1253	flavin adenine dinucleotide binding
EQH49_RS23470	COG2982	Protein involved in outer membrane biogenesis
EQH49_RS23485	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EQH49_RS23490	COG0443	Heat shock 70 kDa protein
EQH49_RS23495	COG2205	protein histidine kinase activity
EQH49_RS23515	COG1301	dicarboxylic acid transport
EQH49_RS23540	COG2205	protein histidine kinase activity
EQH49_RS23545	COG0745	RESPONSE REGULATOR receiver
EQH49_RS23550	COG0826	peptidase U32
EQH49_RS23560	COG4608	Belongs to the ABC transporter superfamily
EQH49_RS23565	COG0444	Belongs to the ABC transporter superfamily
EQH49_RS23570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQH49_RS23575	COG0601	transmembrane transport
EQH49_RS23580	COG0747	negative chemotaxis
EQH49_RS23585	COG4948	Mandelate Racemase Muconate Lactonizing
EQH49_RS23590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQH49_RS23600	COG1070	Carbohydrate kinase
EQH49_RS23625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EQH49_RS23635	COG1830	Aldolase
EQH49_RS23640	COG0351	phosphomethylpyrimidine kinase
EQH49_RS23655	COG0583	DNA-binding transcription factor activity
EQH49_RS23665	COG2252	PERMEase
EQH49_RS23670	COG0583	DNA-binding transcription factor activity
EQH49_RS23675	COG5455	response to cobalt ion
EQH49_RS23695	COG4807	Protein conserved in bacteria
EQH49_RS23705	COG3275	phosphorelay sensor kinase activity
EQH49_RS23715	COG1174	glycine betaine transport
EQH49_RS23720	COG1125	glycine betaine transport
EQH49_RS23725	COG1174	glycine betaine transport
EQH49_RS23730	COG1732	Glycine betaine
EQH49_RS23735	COG1472	Belongs to the glycosyl hydrolase 3 family
EQH49_RS23740	COG0277	FAD linked oxidase domain protein
EQH49_RS23750	COG1686	Belongs to the peptidase S11 family
EQH49_RS23760	COG0586	Pfam SNARE associated Golgi protein
EQH49_RS23765	COG1538	Outer membrane efflux protein
EQH49_RS23770	COG2723	6-phospho-beta-galactosidase activity
EQH49_RS23785	COG3659	wide pore channel activity
EQH49_RS23790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EQH49_RS23800	COG1346	cytolysis
EQH49_RS23810	COG2949	membrane
EQH49_RS23820	COG1129	ABC transporter
EQH49_RS23835	COG2311	Membrane
EQH49_RS23850	COG4771	TonB-dependent receptor
EQH49_RS23855	COG0833	amino acid
EQH49_RS23860	COG0583	DNA-binding transcription factor activity
EQH49_RS23865	COG2855	membrane
EQH49_RS23875	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EQH49_RS23875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQH49_RS23875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQH49_RS23880	COG1105	Belongs to the carbohydrate kinase PfkB family
EQH49_RS23885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS23885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQH49_RS23905	COG1312	Catalyzes the dehydration of D-mannonate
EQH49_RS23910	COG0246	Mannitol dehydrogenase
EQH49_RS23915	COG0523	cobalamin synthesis protein
EQH49_RS23920	COG0671	phosphoesterase, PA-phosphatase related
EQH49_RS23925	COG0791	NLP P60 protein
EQH49_RS23930	COG2200	EAL domain
EQH49_RS23935	COG4166	transmembrane transport
EQH49_RS23940	COG4174	ABC transporter (Permease)
EQH49_RS23945	COG4239	(ABC) transporter, permease
EQH49_RS23950	COG4172	Belongs to the ABC transporter superfamily
EQH49_RS23960	COG2814	Major facilitator Superfamily
EQH49_RS23965	COG1187	pseudouridine synthase activity
EQH49_RS23970	COG1061	Type III restriction enzyme res subunit
EQH49_RS23990	COG0494	nUDIX hydrolase
EQH49_RS23995	COG1349	DNA-binding transcription factor activity
EQH49_RS24025	COG0628	permease
EQH49_RS24040	COG0659	secondary active sulfate transmembrane transporter activity
EQH49_RS24045	COG2239	Acts as a magnesium transporter
EQH49_RS24050	COG4615	Cyclic peptide transporter
EQH49_RS24055	COG3145	DNA-N1-methyladenine dioxygenase activity
EQH49_RS24060	COG2169	Transcriptional regulator
EQH49_RS24060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EQH49_RS24075	COG2198	Histidine kinase
EQH49_RS24075	COG0642	Histidine kinase
EQH49_RS24085	COG0784	Response regulator, receiver
EQH49_RS24085	COG2205	protein histidine kinase activity
EQH49_RS24110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EQH49_RS24115	COG0584	glycerophosphoryl diester phosphodiesterase
EQH49_RS24120	COG2271	Major facilitator Superfamily
EQH49_RS24125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EQH49_RS24135	COG0247	lactate metabolic process
EQH49_RS24145	COG2271	Major facilitator Superfamily
EQH49_RS24155	COG1414	Transcriptional regulator
EQH49_RS24170	COG5464	transposase or invertase
EQH49_RS24180	COG0318	PFAM AMP-dependent synthetase and ligase
EQH49_RS24205	COG1169	isochorismate synthase
EQH49_RS24210	COG2153	protein acetylation
EQH49_RS24225	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EQH49_RS24230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EQH49_RS24240	COG0839	Belongs to the complex I subunit 6 family
EQH49_RS24290	COG0583	DNA-binding transcription factor activity
EQH49_RS24295	COG0436	Aminotransferase
EQH49_RS24305	COG0490	domain, Protein
EQH49_RS24305	COG0471	metal ion transport
EQH49_RS24310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQH49_RS24330	COG0857	belongs to the CobB CobQ family
EQH49_RS24330	COG0280	phosphate acetyltransferase
EQH49_RS24335	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EQH49_RS24340	COG0622	Phosphoesterase
EQH49_RS24345	COG0625	glutathione transferase activity
EQH49_RS24350	COG0625	glutathione transferase activity
EQH49_RS24355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EQH49_RS24360	COG1090	epimerase
EQH49_RS24370	COG4598	ABC transporter
EQH49_RS24375	COG4160	amino acid transport
EQH49_RS24395	COG0163	prenyltransferase activity
EQH49_RS24400	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EQH49_RS24405	COG1286	toxin biosynthetic process
EQH49_RS24410	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EQH49_RS24415	COG0285	dihydrofolate synthase activity
EQH49_RS24425	COG0586	Pfam SNARE associated Golgi protein
EQH49_RS24435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EQH49_RS24455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EQH49_RS24470	COG3101	peptidyl-lysine hydroxylation
EQH49_RS24475	COG0730	response to heat
EQH49_RS24500	COG2062	phosphohistidine phosphatase, SixA
EQH49_RS24515	COG3691	Protein conserved in bacteria
EQH49_RS24525	COG2853	Lipoprotein
EQH49_RS24530	COG2116	formate transmembrane transporter activity
EQH49_RS24540	COG0582	viral genome integration into host DNA
EQH49_RS24545	COG2246	polysaccharide biosynthetic process
EQH49_RS24570	COG3778	Protein conserved in bacteria
EQH49_RS24575	COG3299	homolog of phage Mu protein gp47
EQH49_RS24595	COG4228	DNA circulation
EQH49_RS24620	COG4386	tail sheath protein
EQH49_RS24665	COG4695	Portal protein
EQH49_RS24675	COG4626	Terminase
EQH49_RS24675	COG1802	Transcriptional regulator
EQH49_RS24755	COG0305	Participates in initiation and elongation during chromosome replication
EQH49_RS24810	COG3723	Recombinational DNA repair protein, rece pathway
EQH49_RS24985	COG3266	domain, Protein
EQH49_RS24985	COG4193	domain, Protein
EQH49_RS24985	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQH49_RS25015	COG2885	chlorophyll binding
EQH49_RS25050	COG0583	DNA-binding transcription factor activity
EQH49_RS25055	COG0590	tRNA wobble adenosine to inosine editing
EQH49_RS25060	COG2807	transmembrane transport
EQH49_RS25070	COG0436	Aminotransferase
EQH49_RS25080	COG3275	phosphorelay sensor kinase activity
EQH49_RS25085	COG3279	Response regulator of the LytR AlgR family
EQH49_RS25100	COG3961	Belongs to the TPP enzyme family
EQH49_RS25105	COG0667	Aldo Keto reductase
EQH49_RS25120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQH49_RS25125	COG2199	diguanylate cyclase activity
EQH49_RS25125	COG2200	EAL domain
EQH49_RS25140	COG3415	Transposase
EQH49_RS25145	COG3415	Transposase
EQH49_RS25175	COG0583	DNA-binding transcription factor activity
EQH49_RS25180	COG0385	Bile acid
EQH49_RS25185	COG3530	Putative quorum-sensing-regulated virulence factor
EQH49_RS25205	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQH49_RS25240	COG4319	ketosteroid isomerase
EQH49_RS25250	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EQH49_RS25255	COG4208	sulfate ABC transporter
EQH49_RS25260	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EQH49_RS25265	COG4150	thiosulfate binding
EQH49_RS25275	COG2837	iron assimilation
EQH49_RS25295	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQH49_RS25385	COG4810	utilization protein
EQH49_RS25395	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EQH49_RS25400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EQH49_RS25405	COG5342	invasion associated locus B
EQH49_RS25415	COG0493	'glutamate synthase
EQH49_RS25415	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EQH49_RS25425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EQH49_RS25435	COG1393	Belongs to the ArsC family
EQH49_RS25450	COG0400	carboxylic ester hydrolase activity
EQH49_RS25455	COG1444	tRNA N-acetyltransferase activity
EQH49_RS25460	COG2321	neutral zinc metallopeptidase
EQH49_RS25470	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EQH49_RS25480	COG2716	regulation of RNA biosynthetic process
EQH49_RS25485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EQH49_RS25490	COG0628	permease
EQH49_RS25495	COG4783	chaperone-mediated protein folding
EQH49_RS25500	COG1393	Belongs to the ArsC family
EQH49_RS25515	COG2233	PERMEase
EQH49_RS25525	COG2723	6-phospho-beta-galactosidase activity
EQH49_RS25540	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EQH49_RS25555	COG2200	EAL domain
EQH49_RS25600	COG0516	GMP reductase activity
EQH49_RS25600	COG0517	IMP dehydrogenase activity
EQH49_RS25610	COG1645	bacterial-type flagellum-dependent swarming motility
EQH49_RS25630	COG2976	Protein conserved in bacteria
EQH49_RS25665	COG4953	penicillin-binding protein 1C
EQH49_RS25670	COG2373	Large extracellular alpha-helical protein
EQH49_RS25675	COG2897	thiosulfate sulfurtransferase activity
EQH49_RS25695	COG2975	iron-sulfur cluster assembly
EQH49_RS25700	COG0633	Ferredoxin
EQH49_RS25720	COG0822	iron-sulfur transferase activity
EQH49_RS25750	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EQH49_RS25755	COG3683	transport system, periplasmic component
EQH49_RS25760	COG3711	transcriptional antiterminator
EQH49_RS25765	COG2814	Major facilitator Superfamily
EQH49_RS25770	COG2017	converts alpha-aldose to the beta-anomer
EQH49_RS25775	COG2814	Major facilitator Superfamily
EQH49_RS25775	COG0477	Major facilitator Superfamily
EQH49_RS25780	COG0457	Tetratricopeptide repeat
EQH49_RS25785	COG1940	carbohydrate kinase activity
EQH49_RS25790	COG2259	Doxx family
EQH49_RS25800	COG1017	nitric oxide dioxygenase activity
EQH49_RS25800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EQH49_RS25805	COG0347	Belongs to the P(II) protein family
EQH49_RS25810	COG2204	response regulator
EQH49_RS25815	COG3170	Tfp pilus assembly protein FimV
EQH49_RS25820	COG2205	protein histidine kinase activity
EQH49_RS25830	COG0047	phosphoribosylformylglycinamidine synthase activity
EQH49_RS25830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQH49_RS25845	COG0560	Phosphoserine phosphatase
EQH49_RS25850	COG1737	Transcriptional regulator
EQH49_RS25855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EQH49_RS25865	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EQH49_RS25885	COG0681	Belongs to the peptidase S26 family
EQH49_RS25895	COG3086	response to oxidative stress
EQH49_RS25900	COG3026	antisigma factor binding
EQH49_RS25905	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EQH49_RS25920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EQH49_RS25930	COG0513	Belongs to the DEAD box helicase family
EQH49_RS25945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQH49_RS25950	COG3118	belongs to the thioredoxin family
EQH49_RS25955	COG3148	PFAM DTW domain containing protein
EQH49_RS25965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EQH49_RS25970	COG5544	Lipoprotein
EQH49_RS25975	COG0477	Major facilitator Superfamily
EQH49_RS25980	COG3677	Transposase
EQH49_RS26000	COG0210	DNA helicase
EQH49_RS26005	COG1205	dead DEAH box helicase
EQH49_RS26005	COG1111	helicase
EQH49_RS26015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EQH49_RS26045	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
EQH49_RS26095	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EQH49_RS26100	COG1028	Short-chain dehydrogenase reductase Sdr
EQH49_RS26105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EQH49_RS26110	COG1902	pentaerythritol trinitrate reductase activity
EQH49_RS26120	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQH49_RS26215	COG4372	Transposase
EQH49_RS26220	COG3436	PFAM IS66 Orf2 family protein
EQH49_RS26310	COG2423	ornithine cyclodeaminase activity
EQH49_RS26315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EQH49_RS26320	COG1126	abc transporter atp-binding protein
EQH49_RS26325	COG1126	abc transporter atp-binding protein
EQH49_RS26330	COG0765	amino acid transport
EQH49_RS26335	COG0765	amino acid transport
EQH49_RS26340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQH49_RS26345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQH49_RS26350	COG0006	proline dipeptidase activity
EQH49_RS26355	COG3608	succinylglutamate desuccinylase aspartoacylase
EQH49_RS26390	COG5642	Protein of unknown function (DUF2384)
EQH49_RS26395	COG5654	RES domain protein
EQH49_RS26420	COG4172	Belongs to the ABC transporter superfamily
EQH49_RS26435	COG0601	transmembrane transport
EQH49_RS26440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQH49_RS26540	COG3188	usher protein
EQH49_RS26680	COG1401	restriction endodeoxyribonuclease activity
EQH49_RS26680	COG1401	restriction endodeoxyribonuclease activity
EQH49_RS26705	COG2801	Transposase and inactivated derivatives
EQH49_RS26725	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EQH49_RS26775	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQH49_RS26805	COG0739	heme binding
EQH49_RS26815	COG2132	Multicopper oxidase
EQH49_RS26820	COG3667	copper resistance
EQH49_RS26825	COG2372	response to copper ion
EQH49_RS26830	COG1276	copper resistance
EQH49_RS26835	COG0745	RESPONSE REGULATOR receiver
EQH49_RS26840	COG2205	protein histidine kinase activity
EQH49_RS26880	COG3436	PFAM IS66 Orf2 family protein
EQH49_RS26895	COG4680	protein conserved in bacteria
EQH49_RS26900	COG5499	transcription regulator containing HTH domain
EQH49_RS26960	COG2801	Transposase and inactivated derivatives
EQH49_RS26970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQH49_RS27015	COG2801	Transposase and inactivated derivatives
EQH49_RS27080	COG4221	oxidoreductase activity
EQH49_RS27200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQH49_RS27315	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EQH49_RS27535	COG5499	transcription regulator containing HTH domain
EQH49_RS27620	COG1475	DNA binding
EQH49_RS27685	COG5499	transcription regulator containing HTH domain
EQH49_RS27770	COG1475	DNA binding
EQH49_RS27875	COG1192	Involved in chromosome partitioning
EQH49_RS27950	COG2194	sulfuric ester hydrolase activity
EQH49_RS27960	COG2205	protein histidine kinase activity
EQH49_RS27975	COG3655	Transcriptional regulator
EQH49_RS27990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQH49_RS28000	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EQH49_RS28055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EQH49_RS28165	COG0741	lytic transglycosylase activity
EQH49_RS28190	COG5002	protein histidine kinase activity
EQH49_RS28190	COG2198	Histidine kinase
EQH49_RS28190	COG0784	Response regulator, receiver
EQH49_RS28270	COG2003	Belongs to the UPF0758 family
EQH49_RS28375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EQH49_RS28380	COG2194	sulfuric ester hydrolase activity