locus-tag	class	description
CU111_RS00005	COG0542	response to heat
CU111_RS00030	COG0477	Major facilitator Superfamily
CU111_RS00035	COG5544	Lipoprotein
CU111_RS00040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CU111_RS00050	COG3148	PFAM DTW domain containing protein
CU111_RS00055	COG3118	belongs to the thioredoxin family
CU111_RS00060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CU111_RS00075	COG0513	Belongs to the DEAD box helicase family
CU111_RS00085	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CU111_RS00095	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CU111_RS00100	COG3026	antisigma factor binding
CU111_RS00105	COG3086	response to oxidative stress
CU111_RS00115	COG0681	Belongs to the peptidase S26 family
CU111_RS00135	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CU111_RS00145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CU111_RS00150	COG1737	Transcriptional regulator
CU111_RS00155	COG0560	Phosphoserine phosphatase
CU111_RS00170	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CU111_RS00170	COG0047	phosphoribosylformylglycinamidine synthase activity
CU111_RS00180	COG2205	protein histidine kinase activity
CU111_RS00185	COG3170	Tfp pilus assembly protein FimV
CU111_RS00190	COG2204	response regulator
CU111_RS00195	COG0347	Belongs to the P(II) protein family
CU111_RS00200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CU111_RS00200	COG1017	nitric oxide dioxygenase activity
CU111_RS00215	COG2259	Doxx family
CU111_RS00220	COG1940	carbohydrate kinase activity
CU111_RS00225	COG0457	Tetratricopeptide repeat
CU111_RS00230	COG2814	Major facilitator Superfamily
CU111_RS00230	COG0477	Major facilitator Superfamily
CU111_RS00235	COG2017	converts alpha-aldose to the beta-anomer
CU111_RS00240	COG2814	Major facilitator Superfamily
CU111_RS00245	COG3711	transcriptional antiterminator
CU111_RS00250	COG3683	transport system, periplasmic component
CU111_RS00255	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CU111_RS00285	COG0822	iron-sulfur transferase activity
CU111_RS00305	COG0633	Ferredoxin
CU111_RS00310	COG2975	iron-sulfur cluster assembly
CU111_RS00330	COG2897	thiosulfate sulfurtransferase activity
CU111_RS00335	COG2373	Large extracellular alpha-helical protein
CU111_RS00340	COG4953	penicillin-binding protein 1C
CU111_RS00375	COG2976	Protein conserved in bacteria
CU111_RS00395	COG1645	bacterial-type flagellum-dependent swarming motility
CU111_RS00405	COG0516	GMP reductase activity
CU111_RS00405	COG0517	IMP dehydrogenase activity
CU111_RS00415	COG3119	arylsulfatase activity
CU111_RS00420	COG0641	radical SAM
CU111_RS00440	COG2200	EAL domain
CU111_RS00455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CU111_RS00470	COG2723	6-phospho-beta-galactosidase activity
CU111_RS00480	COG2233	PERMEase
CU111_RS00495	COG1393	Belongs to the ArsC family
CU111_RS00500	COG4783	chaperone-mediated protein folding
CU111_RS00505	COG0628	permease
CU111_RS00510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CU111_RS00515	COG2716	regulation of RNA biosynthetic process
CU111_RS00525	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CU111_RS00535	COG2321	neutral zinc metallopeptidase
CU111_RS00540	COG1444	tRNA N-acetyltransferase activity
CU111_RS00545	COG0400	carboxylic ester hydrolase activity
CU111_RS00560	COG1393	Belongs to the ArsC family
CU111_RS00570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CU111_RS00580	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CU111_RS00580	COG0493	'glutamate synthase
CU111_RS00590	COG5342	invasion associated locus B
CU111_RS00595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CU111_RS00600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CU111_RS00610	COG4810	utilization protein
CU111_RS00700	COG0860	N-Acetylmuramoyl-L-alanine amidase
CU111_RS00720	COG2837	iron assimilation
CU111_RS00730	COG4150	thiosulfate binding
CU111_RS00735	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CU111_RS00740	COG4208	sulfate ABC transporter
CU111_RS00745	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CU111_RS00755	COG4319	ketosteroid isomerase
CU111_RS00790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CU111_RS00810	COG3530	Putative quorum-sensing-regulated virulence factor
CU111_RS00815	COG0385	Bile acid
CU111_RS00820	COG0583	DNA-binding transcription factor activity
CU111_RS00855	COG3415	Transposase
CU111_RS00860	COG3415	Transposase
CU111_RS00875	COG2200	EAL domain
CU111_RS00875	COG2199	diguanylate cyclase activity
CU111_RS00880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CU111_RS00895	COG0667	Aldo Keto reductase
CU111_RS00900	COG3961	Belongs to the TPP enzyme family
CU111_RS00915	COG3279	Response regulator of the LytR AlgR family
CU111_RS00920	COG3275	phosphorelay sensor kinase activity
CU111_RS00930	COG0436	Aminotransferase
CU111_RS00940	COG2807	transmembrane transport
CU111_RS00945	COG0590	tRNA wobble adenosine to inosine editing
CU111_RS00950	COG0583	DNA-binding transcription factor activity
CU111_RS00970	COG2116	formate transmembrane transporter activity
CU111_RS00975	COG2853	Lipoprotein
CU111_RS00990	COG3691	Protein conserved in bacteria
CU111_RS01005	COG2062	phosphohistidine phosphatase, SixA
CU111_RS01030	COG0730	response to heat
CU111_RS01035	COG3101	peptidyl-lysine hydroxylation
CU111_RS01050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CU111_RS01070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CU111_RS01080	COG0586	Pfam SNARE associated Golgi protein
CU111_RS01090	COG0285	dihydrofolate synthase activity
CU111_RS01095	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CU111_RS01100	COG1286	toxin biosynthetic process
CU111_RS01105	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CU111_RS01110	COG0163	prenyltransferase activity
CU111_RS01130	COG4160	amino acid transport
CU111_RS01135	COG4598	ABC transporter
CU111_RS01145	COG1090	epimerase
CU111_RS01150	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CU111_RS01155	COG0625	glutathione transferase activity
CU111_RS01160	COG0625	glutathione transferase activity
CU111_RS01165	COG0622	Phosphoesterase
CU111_RS01170	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CU111_RS01175	COG0857	belongs to the CobB CobQ family
CU111_RS01175	COG0280	phosphate acetyltransferase
CU111_RS01195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CU111_RS01200	COG0471	metal ion transport
CU111_RS01200	COG0490	domain, Protein
CU111_RS01210	COG0436	Aminotransferase
CU111_RS01215	COG0583	DNA-binding transcription factor activity
CU111_RS01270	COG0839	Belongs to the complex I subunit 6 family
CU111_RS01280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CU111_RS01285	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CU111_RS01300	COG2153	protein acetylation
CU111_RS01305	COG1169	isochorismate synthase
CU111_RS01330	COG0318	PFAM AMP-dependent synthetase and ligase
CU111_RS01340	COG5464	transposase or invertase
CU111_RS01360	COG1414	Transcriptional regulator
CU111_RS01370	COG2271	Major facilitator Superfamily
CU111_RS01380	COG0247	lactate metabolic process
CU111_RS01390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CU111_RS01395	COG2271	Major facilitator Superfamily
CU111_RS01400	COG0584	glycerophosphoryl diester phosphodiesterase
CU111_RS01410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CU111_RS01440	COG0784	Response regulator, receiver
CU111_RS01440	COG2205	protein histidine kinase activity
CU111_RS01450	COG0642	Histidine kinase
CU111_RS01450	COG2198	Histidine kinase
CU111_RS01465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CU111_RS01465	COG2169	Transcriptional regulator
CU111_RS01470	COG3145	DNA-N1-methyladenine dioxygenase activity
CU111_RS01475	COG4615	Cyclic peptide transporter
CU111_RS01480	COG2239	Acts as a magnesium transporter
CU111_RS01485	COG0659	secondary active sulfate transmembrane transporter activity
CU111_RS01500	COG0628	permease
CU111_RS01555	COG0582	viral genome integration into host DNA
CU111_RS01585	COG1349	DNA-binding transcription factor activity
CU111_RS01590	COG0494	nUDIX hydrolase
CU111_RS01610	COG1061	Type III restriction enzyme res subunit
CU111_RS01615	COG1187	pseudouridine synthase activity
CU111_RS01620	COG2814	Major facilitator Superfamily
CU111_RS01630	COG4172	Belongs to the ABC transporter superfamily
CU111_RS01635	COG4239	(ABC) transporter, permease
CU111_RS01640	COG4174	ABC transporter (Permease)
CU111_RS01645	COG4166	transmembrane transport
CU111_RS01650	COG2200	EAL domain
CU111_RS01655	COG0791	NLP P60 protein
CU111_RS01660	COG0671	phosphoesterase, PA-phosphatase related
CU111_RS01665	COG0523	cobalamin synthesis protein
CU111_RS01670	COG0246	Mannitol dehydrogenase
CU111_RS01675	COG1312	Catalyzes the dehydration of D-mannonate
CU111_RS01690	COG2814	Major facilitator Superfamily
CU111_RS01700	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS01700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS01705	COG1105	Belongs to the carbohydrate kinase PfkB family
CU111_RS01710	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CU111_RS01710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU111_RS01710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU111_RS01720	COG2855	membrane
CU111_RS01730	COG0583	DNA-binding transcription factor activity
CU111_RS01735	COG0833	amino acid
CU111_RS01745	COG4771	TonB-dependent receptor
CU111_RS01760	COG2311	Membrane
CU111_RS01775	COG1129	ABC transporter
CU111_RS01785	COG2949	membrane
CU111_RS01795	COG1346	cytolysis
CU111_RS01805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CU111_RS01810	COG3659	wide pore channel activity
CU111_RS01825	COG2723	6-phospho-beta-galactosidase activity
CU111_RS01830	COG1538	Outer membrane efflux protein
CU111_RS01835	COG0586	Pfam SNARE associated Golgi protein
CU111_RS01845	COG1686	Belongs to the peptidase S11 family
CU111_RS01860	COG1472	Belongs to the glycosyl hydrolase 3 family
CU111_RS01865	COG1732	Glycine betaine
CU111_RS01870	COG1174	glycine betaine transport
CU111_RS01875	COG1125	glycine betaine transport
CU111_RS01880	COG1174	glycine betaine transport
CU111_RS01900	COG4807	Protein conserved in bacteria
CU111_RS01920	COG5455	response to cobalt ion
CU111_RS01925	COG0583	DNA-binding transcription factor activity
CU111_RS01930	COG2252	PERMEase
CU111_RS01940	COG0583	DNA-binding transcription factor activity
CU111_RS01955	COG0351	phosphomethylpyrimidine kinase
CU111_RS01960	COG1830	Aldolase
CU111_RS01995	COG1070	Carbohydrate kinase
CU111_RS02005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CU111_RS02015	COG0826	peptidase U32
CU111_RS02020	COG0745	RESPONSE REGULATOR receiver
CU111_RS02025	COG2205	protein histidine kinase activity
CU111_RS02050	COG1301	dicarboxylic acid transport
CU111_RS02070	COG0443	Heat shock 70 kDa protein
CU111_RS02080	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CU111_RS02095	COG2982	Protein involved in outer membrane biogenesis
CU111_RS02100	COG1253	flavin adenine dinucleotide binding
CU111_RS02135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CU111_RS02150	COG2244	polysaccharide biosynthetic process
CU111_RS02175	COG1088	dTDP-glucose 4,6-dehydratase activity
CU111_RS02230	COG0438	transferase activity, transferring glycosyl groups
CU111_RS02235	COG1442	glycosyl transferase family 8
CU111_RS02235	COG1216	Glycosyl transferase, family 2
CU111_RS02245	COG0463	Glycosyl transferase, family 2
CU111_RS02270	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CU111_RS02300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CU111_RS02305	COG0583	DNA-binding transcription factor activity
CU111_RS02315	COG0531	amino acid
CU111_RS02320	COG0640	Transcriptional regulator
CU111_RS02325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CU111_RS02330	COG2925	Exonuclease
CU111_RS02345	COG1289	transmembrane transporter activity
CU111_RS02365	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CU111_RS02375	COG1942	4-Oxalocrotonate Tautomerase
CU111_RS02380	COG0583	DNA-binding transcription factor activity
CU111_RS02385	COG0095	Lipoate-protein ligase
CU111_RS02390	COG0477	Major facilitator Superfamily
CU111_RS02405	COG3300	MHYT domain
CU111_RS02405	COG5001	Diguanylate cyclase
CU111_RS02415	COG3615	Tellurite resistance protein tehB
CU111_RS02440	COG3706	GGDEF domain
CU111_RS02460	COG0534	Mate efflux family protein
CU111_RS02470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CU111_RS02490	COG0604	alcohol dehydrogenase
CU111_RS02495	COG1309	transcriptional regulator
CU111_RS02515	COG0025	NhaP-type Na H and K H
CU111_RS02565	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CU111_RS02575	COG1418	mRNA catabolic process
CU111_RS02580	COG0270	DNA (cytosine-5-)-methyltransferase activity
CU111_RS02585	COG3727	T/G mismatch-specific endonuclease activity
CU111_RS02590	COG0697	spore germination
CU111_RS02595	COG2354	Protein conserved in bacteria
CU111_RS02625	COG0366	Alpha amylase catalytic
CU111_RS02630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU111_RS02640	COG0765	amino acid transport
CU111_RS02645	COG1126	abc transporter atp-binding protein
CU111_RS02650	COG2197	response regulator
CU111_RS02660	COG2197	response regulator
CU111_RS02695	COG3318	Belongs to the UPF0149 family
CU111_RS02695	COG3012	SEC-C Motif Domain Protein
CU111_RS02700	COG0814	amino acid
CU111_RS02710	COG1528	Iron-storage protein
CU111_RS02725	COG0477	Major facilitator Superfamily
CU111_RS02735	COG2211	Major facilitator Superfamily
CU111_RS02745	COG1528	Iron-storage protein
CU111_RS02755	COG1879	ABC-type sugar transport system periplasmic component
CU111_RS02765	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU111_RS02790	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CU111_RS02800	COG3102	Protein conserved in bacteria
CU111_RS02820	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CU111_RS02825	COG1801	Protein of unknown function DUF72
CU111_RS02830	COG1335	isochorismatase
CU111_RS02840	COG0494	nUDIX hydrolase
CU111_RS02865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CU111_RS02875	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CU111_RS02880	COG0739	heme binding
CU111_RS02885	COG1560	Kdo2-lipid A biosynthetic process
CU111_RS02895	COG1737	Transcriptional regulator
CU111_RS02910	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CU111_RS02915	COG0129	dihydroxy-acid dehydratase activity
CU111_RS02920	COG0800	Aldolase
CU111_RS02930	COG3141	response to X-ray
CU111_RS02935	COG2979	Protein of unknown function (DUF533)
CU111_RS02940	COG1770	oligopeptidase
CU111_RS02945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CU111_RS02955	COG2372	response to copper ion
CU111_RS02960	COG1276	copper resistance
CU111_RS02975	COG2990	Protein conserved in bacteria
CU111_RS03000	COG3008	intermembrane lipid transfer
CU111_RS03005	COG2995	paraquat-inducible protein a
CU111_RS03010	COG1956	GAF domain-containing protein
CU111_RS03030	COG2814	Major facilitator Superfamily
CU111_RS03040	COG1414	Transcriptional regulator
CU111_RS03080	COG0768	penicillin binding
CU111_RS03085	COG2226	methyltransferase
CU111_RS03100	COG3716	PTS system mannose fructose sorbose family IID component
CU111_RS03105	COG3715	PTS system
CU111_RS03110	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU111_RS03110	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS03115	COG1253	flavin adenine dinucleotide binding
CU111_RS03120	COG2200	EAL domain
CU111_RS03125	COG1760	l-serine dehydratase
CU111_RS03145	COG0251	oxidation-reduction process
CU111_RS03150	COG1199	ATP-dependent helicase activity
CU111_RS03160	COG3065	identical protein binding
CU111_RS03170	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CU111_RS03180	COG2894	cell division
CU111_RS03195	COG0179	Fumarylacetoacetate (FAA) hydrolase
CU111_RS03225	COG2719	SpoVR family
CU111_RS03245	COG1619	proteins homologs of microcin C7 resistance protein MccF
CU111_RS03255	COG4774	siderophore transport
CU111_RS03270	COG2308	Evidence 4 Homologs of previously reported genes of
CU111_RS03320	COG0583	DNA-binding transcription factor activity
CU111_RS03325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CU111_RS03340	COG1882	Formate acetyltransferase
CU111_RS03370	COG0583	DNA-binding transcription factor activity
CU111_RS03400	COG0583	DNA-binding transcription factor activity
CU111_RS03415	COG3122	Protein conserved in bacteria
CU111_RS03440	COG2885	chlorophyll binding
CU111_RS03515	COG0012	GTP binding
CU111_RS03535	COG0659	secondary active sulfate transmembrane transporter activity
CU111_RS03570	COG2890	protein-(glutamine-N5) methyltransferase activity
CU111_RS03590	COG0387	Pfam Sodium calcium exchanger
CU111_RS03595	COG4572	Cation transport regulator
CU111_RS03600	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CU111_RS03615	COG3707	response regulator
CU111_RS03620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CU111_RS03630	COG1116	anion transmembrane transporter activity
CU111_RS03635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CU111_RS03635	COG2146	nitrite reductase [NAD(P)H] activity
CU111_RS03640	COG0243	molybdopterin cofactor binding
CU111_RS03645	COG4932	domain protein
CU111_RS03650	COG2197	response regulator
CU111_RS03655	COG3850	Histidine kinase
CU111_RS03660	COG2223	nitrite transmembrane transporter activity
CU111_RS03665	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CU111_RS03670	COG1140	nitrate reductase beta subunit
CU111_RS03675	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CU111_RS03680	COG2181	nitrate reductase activity
CU111_RS03690	COG1522	sequence-specific DNA binding
CU111_RS03725	COG0788	formyltetrahydrofolate deformylase activity
CU111_RS03735	COG1752	Esterase of the alpha-beta hydrolase superfamily
CU111_RS03740	COG0745	RESPONSE REGULATOR receiver
CU111_RS03745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CU111_RS03750	COG2916	Histone family protein nucleoid-structuring protein H-NS
CU111_RS03755	COG1435	thymidine kinase activity
CU111_RS03760	COG1454	alcohol dehydrogenase
CU111_RS03760	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS03770	COG2095	MarC family integral membrane protein
CU111_RS03775	COG4166	transmembrane transport
CU111_RS03780	COG0601	transmembrane transport
CU111_RS03785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU111_RS03790	COG0444	Belongs to the ABC transporter superfamily
CU111_RS03800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CU111_RS03820	COG2353	YceI-like domain
CU111_RS03825	COG2350	Protein conserved in bacteria
CU111_RS03835	COG3001	Fructosamine kinase
CU111_RS03845	COG1105	Belongs to the carbohydrate kinase PfkB family
CU111_RS03850	COG3137	Salt-induced outer membrane protein
CU111_RS03890	COG0072	phenylalanine-tRNA ligase activity
CU111_RS03890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CU111_RS03910	COG0583	DNA-binding transcription factor activity
CU111_RS03930	COG0386	Belongs to the glutathione peroxidase family
CU111_RS03940	COG0791	NLP P60 protein
CU111_RS03950	COG4256	Hemin uptake protein
CU111_RS03955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CU111_RS03965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CU111_RS03965	COG0574	Belongs to the PEP-utilizing enzyme family
CU111_RS03975	COG0628	permease
CU111_RS03980	COG0247	lactate metabolic process
CU111_RS03980	COG0277	FAD linked oxidase domain protein
CU111_RS03985	COG2050	protein possibly involved in aromatic compounds catabolism
CU111_RS03990	COG2261	transglycosylase associated protein
CU111_RS04020	COG1120	ATPase activity
CU111_RS04025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU111_RS04035	COG0583	DNA-binding transcription factor activity
CU111_RS04060	COG1304	FMN binding
CU111_RS04065	COG1309	transcriptional regulator
CU111_RS04080	COG0316	Belongs to the HesB IscA family
CU111_RS04085	COG0719	Fe-S assembly protein
CU111_RS04090	COG0396	ATPase activity
CU111_RS04095	COG0719	Fe-S assembly protein
CU111_RS04110	COG1376	ErfK ybiS ycfS ynhG family protein
CU111_RS04135	COG1309	transcriptional regulator
CU111_RS04140	COG1082	Xylose isomerase domain protein TIM barrel
CU111_RS04140	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CU111_RS04145	COG2271	Major facilitator Superfamily
CU111_RS04150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CU111_RS04160	COG1120	ATPase activity
CU111_RS04165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU111_RS04170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CU111_RS04175	COG1414	Transcriptional regulator
CU111_RS04210	COG2814	Major facilitator Superfamily
CU111_RS04230	COG0583	DNA-binding transcription factor activity
CU111_RS04235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CU111_RS04255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CU111_RS04260	COG1116	anion transmembrane transporter activity
CU111_RS04265	COG4774	siderophore transport
CU111_RS04270	COG1120	ATPase activity
CU111_RS04275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU111_RS04280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU111_RS04300	COG0765	amino acid transport
CU111_RS04305	COG1126	abc transporter atp-binding protein
CU111_RS04335	COG1473	amidohydrolase
CU111_RS04340	COG3383	formate dehydrogenase (NAD+) activity
CU111_RS04345	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CU111_RS04360	COG1175	transmembrane transport
CU111_RS04395	COG1857	crispr-associated protein
CU111_RS04405	COG1518	maintenance of DNA repeat elements
CU111_RS04410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CU111_RS04415	COG3157	Type VI secretion system effector, Hcp
CU111_RS04445	COG4133	protoheme IX ABC transporter activity
CU111_RS04450	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CU111_RS04455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CU111_RS04470	COG1138	Cytochrome C-type biogenesis protein
CU111_RS04475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CU111_RS04480	COG3088	subunit of a heme lyase
CU111_RS04480	COG4235	cytochrome complex assembly
CU111_RS04530	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS04535	COG2610	gluconate transmembrane transporter activity
CU111_RS04540	COG1250	3-hydroxyacyl-CoA dehydrogenase
CU111_RS04550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CU111_RS04560	COG0583	DNA-binding transcription factor activity
CU111_RS04580	COG0277	FAD linked oxidase domain protein
CU111_RS04585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CU111_RS04610	COG0402	S-adenosylhomocysteine deaminase activity
CU111_RS04655	COG2200	EAL domain
CU111_RS04670	COG2205	protein histidine kinase activity
CU111_RS04675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU111_RS04695	COG2200	EAL domain
CU111_RS04750	COG2814	Major facilitator Superfamily
CU111_RS04755	COG1082	Xylose isomerase domain protein TIM barrel
CU111_RS04765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU111_RS04795	COG4608	Belongs to the ABC transporter superfamily
CU111_RS04800	COG0444	Belongs to the ABC transporter superfamily
CU111_RS04825	COG0346	lactoylglutathione lyase activity
CU111_RS04830	COG1349	DNA-binding transcription factor activity
CU111_RS04860	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CU111_RS04880	COG0300	oxidoreductase activity
CU111_RS04925	COG0307	riboflavin synthase, alpha
CU111_RS04930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CU111_RS04935	COG2814	Major facilitator Superfamily
CU111_RS04940	COG0583	DNA-binding transcription factor activity
CU111_RS04955	COG2814	Major facilitator Superfamily
CU111_RS04970	COG0791	NLP P60 protein
CU111_RS04975	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CU111_RS04985	COG0346	lactoylglutathione lyase activity
CU111_RS04990	COG1902	pentaerythritol trinitrate reductase activity
CU111_RS04995	COG1309	transcriptional regulator
CU111_RS05000	COG3313	Fe-S protein
CU111_RS05005	COG4989	oxidoreductase activity
CU111_RS05010	COG2032	superoxide dismutase activity
CU111_RS05015	COG1289	transmembrane transporter activity
CU111_RS05020	COG1566	PFAM secretion protein HlyD family protein
CU111_RS05035	COG3706	GGDEF domain
CU111_RS05050	COG3895	Periplasmic Protein
CU111_RS05065	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CU111_RS05070	COG0625	glutathione transferase activity
CU111_RS05085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CU111_RS05095	COG4659	FMN binding
CU111_RS05130	COG2723	6-phospho-beta-galactosidase activity
CU111_RS05140	COG0673	inositol 2-dehydrogenase activity
CU111_RS05150	COG2814	Major facilitator Superfamily
CU111_RS05170	COG3038	cytochrome b561
CU111_RS05190	COG0583	DNA-binding transcription factor activity
CU111_RS05195	COG3485	protocatechuate 3,4-dioxygenase
CU111_RS05200	COG3485	protocatechuate 3,4-dioxygenase
CU111_RS05205	COG5383	Protein conserved in bacteria
CU111_RS05210	COG2272	Belongs to the type-B carboxylesterase lipase family
CU111_RS05225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CU111_RS05230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CU111_RS05235	COG1275	C4-dicarboxylate transporter malic acid transport protein
CU111_RS05240	COG0500	methyltransferase
CU111_RS05255	COG0697	spore germination
CU111_RS05260	COG3708	Transcriptional regulator
CU111_RS05260	COG2207	Transcriptional regulator
CU111_RS05265	COG3135	benzoate transporter
CU111_RS05270	COG1396	sequence-specific DNA binding
CU111_RS05280	COG0826	peptidase U32
CU111_RS05300	COG1294	oxidase, subunit
CU111_RS05305	COG1271	oxidase subunit
CU111_RS05310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CU111_RS05315	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CU111_RS05320	COG3842	ATPase activity
CU111_RS05325	COG1176	ABC-type spermidine putrescine transport system, permease component I
CU111_RS05330	COG1177	transmembrane transport
CU111_RS05335	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS05365	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS05370	COG0747	negative chemotaxis
CU111_RS05380	COG3238	Protein conserved in bacteria
CU111_RS05385	COG1247	-acetyltransferase
CU111_RS05395	COG2130	NADP-dependent
CU111_RS05410	COG3691	Protein conserved in bacteria
CU111_RS05415	COG1228	amidohydrolase
CU111_RS05420	COG4772	TonB-dependent receptor
CU111_RS05445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CU111_RS05450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CU111_RS05455	COG1473	amidohydrolase
CU111_RS05460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CU111_RS05465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU111_RS05475	COG0765	amino acid transport
CU111_RS05480	COG1126	abc transporter atp-binding protein
CU111_RS05490	COG0625	glutathione transferase activity
CU111_RS05520	COG2211	Major facilitator Superfamily
CU111_RS05535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CU111_RS05540	COG3842	ATPase activity
CU111_RS05545	COG1840	ABC-type Fe3 transport system, periplasmic component
CU111_RS05550	COG1178	ABC-type Fe3 transport system permease component
CU111_RS05560	COG2181	nitrate reductase activity
CU111_RS05565	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CU111_RS05575	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CU111_RS05595	COG1414	Transcriptional regulator
CU111_RS05600	COG4948	Mandelate Racemase Muconate Lactonizing
CU111_RS05605	COG4829	muconolactone delta-isomerase
CU111_RS05610	COG3485	protocatechuate 3,4-dioxygenase
CU111_RS05620	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CU111_RS05640	COG0243	molybdopterin cofactor binding
CU111_RS05640	COG3383	formate dehydrogenase (NAD+) activity
CU111_RS05645	COG0243	molybdopterin cofactor binding
CU111_RS05645	COG3383	formate dehydrogenase (NAD+) activity
CU111_RS05650	COG0437	4 iron, 4 sulfur cluster binding
CU111_RS05655	COG2864	formate dehydrogenase
CU111_RS05670	COG2326	polyphosphate kinase activity
CU111_RS05680	COG2814	Major facilitator Superfamily
CU111_RS05690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CU111_RS05700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU111_RS05710	COG0747	negative chemotaxis
CU111_RS05715	COG1064	alcohol dehydrogenase
CU111_RS05730	COG0488	(ABC) transporter
CU111_RS05765	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS05770	COG3729	General stress protein
CU111_RS05785	COG3685	Protein conserved in bacteria
CU111_RS05795	COG0366	Alpha amylase catalytic
CU111_RS05805	COG2323	membrane
CU111_RS05815	COG3111	PFAM Bacterial OB fold (BOF) protein
CU111_RS05820	COG1764	response to oxidative stress
CU111_RS05845	COG3781	membrane
CU111_RS05850	COG0243	molybdopterin cofactor binding
CU111_RS05855	COG0583	DNA-binding transcription factor activity
CU111_RS05860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU111_RS05885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU111_RS05890	COG1447	Phosphotransferase system cellobiose-specific component IIA
CU111_RS05895	COG2814	Major facilitator Superfamily
CU111_RS05905	COG1285	pathogenesis
CU111_RS05910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CU111_RS05930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CU111_RS05930	COG0519	Catalyzes the synthesis of GMP from XMP
CU111_RS05970	COG0596	Alpha beta hydrolase
CU111_RS05980	COG2205	protein histidine kinase activity
CU111_RS05995	COG0076	glutamate decarboxylase activity
CU111_RS06000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CU111_RS06005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CU111_RS06010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CU111_RS06015	COG1116	anion transmembrane transporter activity
CU111_RS06020	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CU111_RS06035	COG0673	inositol 2-dehydrogenase activity
CU111_RS06045	COG1609	Transcriptional regulator
CU111_RS06050	COG3706	GGDEF domain
CU111_RS06055	COG0402	S-adenosylhomocysteine deaminase activity
CU111_RS06060	COG1953	Uracil, thiamine, allantoin
CU111_RS06095	COG0596	Alpha beta hydrolase
CU111_RS06110	COG2207	Transcriptional regulator
CU111_RS06130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CU111_RS06150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CU111_RS06195	COG0765	amino acid transport
CU111_RS06205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CU111_RS06215	COG2070	2-Nitropropane dioxygenase
CU111_RS06220	COG0583	DNA-binding transcription factor activity
CU111_RS06230	COG1902	pentaerythritol trinitrate reductase activity
CU111_RS06235	COG4529	Protein conserved in bacteria
CU111_RS06240	COG0477	Major facilitator Superfamily
CU111_RS06270	COG2223	nitrite transmembrane transporter activity
CU111_RS06280	COG1609	Transcriptional regulator
CU111_RS06285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS06295	COG3037	sugar-specific permease SgaT UlaA
CU111_RS06300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CU111_RS06310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU111_RS06315	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CU111_RS06315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU111_RS06315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU111_RS06340	COG3436	PFAM IS66 Orf2 family protein
CU111_RS06345	COG4372	Transposase
CU111_RS06355	COG0583	DNA-binding transcription factor activity
CU111_RS06360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CU111_RS06370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CU111_RS06385	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU111_RS06395	COG1609	Transcriptional regulator
CU111_RS06425	COG1652	LysM domain
CU111_RS06455	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CU111_RS06455	COG0456	acetyltransferase
CU111_RS06465	COG0667	Aldo Keto reductase
CU111_RS06475	COG3386	PFAM SMP-30 Gluconolaconase
CU111_RS06480	COG0667	Aldo Keto reductase
CU111_RS06495	COG1473	amidohydrolase
CU111_RS06510	COG0251	oxidation-reduction process
CU111_RS06515	COG0583	DNA-binding transcription factor activity
CU111_RS06520	COG0626	cystathionine gamma-synthase activity
CU111_RS06525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CU111_RS06530	COG0814	amino acid
CU111_RS06535	COG0583	DNA-binding transcription factor activity
CU111_RS06545	COG1294	oxidase, subunit
CU111_RS06550	COG1271	oxidase subunit
CU111_RS06560	COG3118	belongs to the thioredoxin family
CU111_RS06590	COG0583	DNA-binding transcription factor activity
CU111_RS06630	COG1929	Belongs to the glycerate kinase type-1 family
CU111_RS06635	COG3835	regulator
CU111_RS06655	COG2186	Transcriptional regulator
CU111_RS06660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU111_RS06660	COG1263	PTS System
CU111_RS06670	COG2814	Major facilitator Superfamily
CU111_RS06675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS06675	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS06685	COG2819	hydrolase of the alpha beta superfamily
CU111_RS06690	COG3300	MHYT domain
CU111_RS06690	COG5001	Diguanylate cyclase
CU111_RS06725	COG3188	usher protein
CU111_RS06740	COG1649	PFAM Uncharacterised BCR, COG1649
CU111_RS06745	COG3550	peptidyl-serine autophosphorylation
CU111_RS06750	COG1396	sequence-specific DNA binding
CU111_RS06755	COG2351	hydroxyisourate hydrolase activity
CU111_RS06760	COG3195	allantoin biosynthetic process
CU111_RS06760	COG3648	Uricase
CU111_RS06765	COG2233	PERMEase
CU111_RS06795	COG2207	Transcriptional regulator
CU111_RS06810	COG4628	conserved protein (DUF2132)
CU111_RS06830	COG2011	ABC-type metal ion transport system permease component
CU111_RS06835	COG2070	2-Nitropropane dioxygenase
CU111_RS06845	COG0477	Major facilitator Superfamily
CU111_RS06920	COG2199	diguanylate cyclase activity
CU111_RS06935	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS06940	COG0583	DNA-binding transcription factor activity
CU111_RS06950	COG0039	L-malate dehydrogenase activity
CU111_RS06955	COG1349	DNA-binding transcription factor activity
CU111_RS06960	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CU111_RS06965	COG3395	kinase activity
CU111_RS06975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CU111_RS06980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CU111_RS06985	COG2271	Major facilitator Superfamily
CU111_RS07010	COG4977	sequence-specific DNA binding
CU111_RS07020	COG0697	spore germination
CU111_RS07025	COG2814	Major facilitator Superfamily
CU111_RS07040	COG1129	ABC transporter
CU111_RS07055	COG0683	leucine binding
CU111_RS07060	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CU111_RS07095	COG2223	nitrite transmembrane transporter activity
CU111_RS07100	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CU111_RS07115	COG1349	DNA-binding transcription factor activity
CU111_RS07120	COG2084	Dehydrogenase
CU111_RS07125	COG3395	kinase activity
CU111_RS07130	COG0235	Class ii aldolase
CU111_RS07135	COG3622	Belongs to the hyi family
CU111_RS07140	COG2610	gluconate transmembrane transporter activity
CU111_RS07145	COG3708	Transcriptional regulator
CU111_RS07145	COG2207	Transcriptional regulator
CU111_RS07160	COG2200	EAL domain
CU111_RS07165	COG1546	Belongs to the CinA family
CU111_RS07170	COG0071	Belongs to the small heat shock protein (HSP20) family
CU111_RS07200	COG2135	peptidase activity
CU111_RS07205	COG2207	Transcriptional regulator
CU111_RS07220	COG4221	oxidoreductase activity
CU111_RS07225	COG1802	Transcriptional regulator
CU111_RS07230	COG0589	response to stress
CU111_RS07235	COG0246	Mannitol dehydrogenase
CU111_RS07240	COG2271	Major facilitator Superfamily
CU111_RS07255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CU111_RS07270	COG0243	molybdopterin cofactor binding
CU111_RS07275	COG0437	4 iron, 4 sulfur cluster binding
CU111_RS07280	COG3302	dmso reductase anchor subunit
CU111_RS07295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CU111_RS07300	COG1940	carbohydrate kinase activity
CU111_RS07305	COG0583	DNA-binding transcription factor activity
CU111_RS07310	COG2814	Major facilitator Superfamily
CU111_RS07315	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CU111_RS07325	COG3591	Belongs to the peptidase S1B family
CU111_RS07345	COG0628	permease
CU111_RS07375	COG0679	Auxin Efflux Carrier
CU111_RS07385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CU111_RS07410	COG3290	protein histidine kinase activity
CU111_RS07415	COG4565	transcriptional regulatory protein
CU111_RS07440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CU111_RS07440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CU111_RS07460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CU111_RS07465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CU111_RS07475	COG0183	Belongs to the thiolase family
CU111_RS07480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CU111_RS07490	COG1414	Transcriptional regulator
CU111_RS07495	COG2840	Smr protein MutS2
CU111_RS07500	COG0583	DNA-binding transcription factor activity
CU111_RS07510	COG1473	amidohydrolase
CU111_RS07515	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CU111_RS07530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CU111_RS07545	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CU111_RS07550	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CU111_RS07570	COG0531	amino acid
CU111_RS07580	COG3136	membrane protein required for alginate biosynthesis
CU111_RS07585	COG0745	RESPONSE REGULATOR receiver
CU111_RS07595	COG2205	protein histidine kinase activity
CU111_RS07605	COG0114	fumarate hydratase activity
CU111_RS07610	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CU111_RS07610	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CU111_RS07615	COG1482	cell wall glycoprotein biosynthetic process
CU111_RS07620	COG5339	Protein conserved in bacteria
CU111_RS07625	COG1609	Transcriptional regulator
CU111_RS07630	COG1263	PTS System
CU111_RS07630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU111_RS07635	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CU111_RS07665	COG0425	Belongs to the sulfur carrier protein TusA family
CU111_RS07670	COG5562	phage envelope protein
CU111_RS07675	COG0401	homolog of Blt101
CU111_RS07680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CU111_RS07685	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS07690	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CU111_RS07695	COG0477	Major facilitator Superfamily
CU111_RS07700	COG1113	amino acid transport
CU111_RS07705	COG2988	succinylglutamate desuccinylase activity
CU111_RS07710	COG3724	N-succinylarginine dihydrolase activity
CU111_RS07715	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS07720	COG3138	arginine N-succinyltransferase
CU111_RS07725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CU111_RS07730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CU111_RS07735	COG0667	Aldo Keto reductase
CU111_RS07740	COG0583	DNA-binding transcription factor activity
CU111_RS07765	COG4122	O-methyltransferase activity
CU111_RS07770	COG1643	Atp-dependent helicase
CU111_RS07785	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CU111_RS07790	COG3327	negative regulation of DNA-templated transcription, initiation
CU111_RS07795	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CU111_RS07800	COG0183	Belongs to the thiolase family
CU111_RS07805	COG2050	protein possibly involved in aromatic compounds catabolism
CU111_RS07810	COG1250	3-hydroxyacyl-CoA dehydrogenase
CU111_RS07815	COG1024	Enoyl-CoA hydratase
CU111_RS07820	COG1024	Enoyl-CoA hydratase
CU111_RS07825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CU111_RS07830	COG2151	metal-sulfur cluster biosynthetic enzyme
CU111_RS07835	COG3396	Phenylacetate-CoA oxygenase
CU111_RS07840	COG3460	Phenylacetate-CoA oxygenase
CU111_RS07845	COG3396	Phenylacetate-CoA oxygenase
CU111_RS07850	COG2030	dehydratase
CU111_RS07850	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS07880	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS07885	COG2207	Transcriptional regulator
CU111_RS07890	COG3784	Protein of unknown function (DUF1318)
CU111_RS07900	COG2911	Protein conserved in bacteria
CU111_RS07905	COG0586	Pfam SNARE associated Golgi protein
CU111_RS07910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CU111_RS07915	COG3187	Heat shock protein
CU111_RS07920	COG3042	response to heat
CU111_RS07930	COG1013	pyruvate-flavodoxin oxidoreductase activity
CU111_RS07930	COG0674	pyruvate-flavodoxin oxidoreductase activity
CU111_RS07930	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CU111_RS07930	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CU111_RS07935	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CU111_RS07945	COG0589	response to stress
CU111_RS07955	COG0513	Belongs to the DEAD box helicase family
CU111_RS07975	COG1349	DNA-binding transcription factor activity
CU111_RS07980	COG0673	inositol 2-dehydrogenase activity
CU111_RS07995	COG1113	amino acid transport
CU111_RS08000	COG1522	sequence-specific DNA binding
CU111_RS08010	COG1448	Aminotransferase
CU111_RS08015	COG2011	ABC-type metal ion transport system permease component
CU111_RS08030	COG0436	Aminotransferase
CU111_RS08035	COG0604	alcohol dehydrogenase
CU111_RS08060	COG0583	DNA-binding transcription factor activity
CU111_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS08085	COG1309	transcriptional regulator
CU111_RS08090	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS08215	COG2885	chlorophyll binding
CU111_RS08240	COG0693	protein deglycase activity
CU111_RS08245	COG1078	dGTPase activity
CU111_RS08250	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS08255	COG0583	DNA-binding transcription factor activity
CU111_RS08320	COG3250	beta-galactosidase activity
CU111_RS08325	COG0656	L-ascorbic acid biosynthetic process
CU111_RS08355	COG4166	transmembrane transport
CU111_RS08360	COG2866	Carboxypeptidase
CU111_RS08365	COG4948	Mandelate Racemase Muconate Lactonizing
CU111_RS08370	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CU111_RS08375	COG3180	Ammonia monooxygenase
CU111_RS08385	COG1486	melibiose metabolic process
CU111_RS08390	COG0583	DNA-binding transcription factor activity
CU111_RS08400	COG3106	COG3106 Predicted ATPase
CU111_RS08410	COG1983	PspC domain protein
CU111_RS08420	COG1842	Phage shock protein A
CU111_RS08425	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CU111_RS08435	COG1473	amidohydrolase
CU111_RS08450	COG0702	epimerase
CU111_RS08465	COG4171	peptide transport system, permease
CU111_RS08480	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CU111_RS08490	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CU111_RS08495	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CU111_RS08495	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CU111_RS08510	COG1349	DNA-binding transcription factor activity
CU111_RS08520	COG0023	Translation Initiation Factor
CU111_RS08530	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CU111_RS08535	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CU111_RS08540	COG0671	phosphoesterase, PA-phosphatase related
CU111_RS08550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CU111_RS08580	COG0616	signal peptide processing
CU111_RS08590	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS08595	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CU111_RS08625	COG0583	DNA-binding transcription factor activity
CU111_RS08635	COG0009	L-threonylcarbamoyladenylate synthase
CU111_RS08645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CU111_RS08650	COG0512	Glutamine amidotransferase of anthranilate synthase
CU111_RS08650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CU111_RS08655	COG0135	phosphoribosylanthranilate isomerase activity
CU111_RS08655	COG0134	indole-3-glycerol-phosphate synthase activity
CU111_RS08710	COG4774	siderophore transport
CU111_RS08720	COG3047	cAMP biosynthetic process
CU111_RS08725	COG0727	PFAM Uncharacterised protein family (UPF0153)
CU111_RS08755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CU111_RS08760	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS08765	COG1988	membrane-bound metal-dependent
CU111_RS08770	COG1823	symporter activity
CU111_RS08790	COG1486	melibiose metabolic process
CU111_RS08795	COG2169	Transcriptional regulator
CU111_RS08795	COG1917	Cupin 2, conserved barrel domain protein
CU111_RS08800	COG1447	Phosphotransferase system cellobiose-specific component IIA
CU111_RS08805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU111_RS08810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU111_RS08815	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CU111_RS08825	COG0322	excinuclease ABC activity
CU111_RS08830	COG3678	ATP-independent chaperone mediated protein folding
CU111_RS08840	COG3724	N-succinylarginine dihydrolase activity
CU111_RS08850	COG3138	arginine N-succinyltransferase
CU111_RS08860	COG0708	Exodeoxyribonuclease III
CU111_RS08865	COG0398	Pfam SNARE associated Golgi protein
CU111_RS08870	COG0398	Pfam SNARE associated Golgi protein
CU111_RS08875	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CU111_RS08880	COG4134	Bacterial extracellular solute-binding protein
CU111_RS08885	COG4135	transport system, permease component
CU111_RS08890	COG4136	ATPase activity
CU111_RS08895	COG2897	thiosulfate sulfurtransferase activity
CU111_RS08900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CU111_RS08905	COG0494	nUDIX hydrolase
CU111_RS08910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CU111_RS08915	COG3321	synthase
CU111_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS08915	COG0604	alcohol dehydrogenase
CU111_RS08920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CU111_RS08925	COG0709	Synthesizes selenophosphate from selenide and ATP
CU111_RS08945	COG0778	Nitroreductase
CU111_RS08950	COG0616	signal peptide processing
CU111_RS08955	COG0252	asparaginase activity
CU111_RS08960	COG1335	isochorismatase
CU111_RS08975	COG3139	Protein of unknown function (DUF1315)
CU111_RS08995	COG0656	L-ascorbic acid biosynthetic process
CU111_RS09000	COG3713	MltA-interacting MipA family protein
CU111_RS09005	COG2766	serine protein kinase
CU111_RS09020	COG0386	Belongs to the glutathione peroxidase family
CU111_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS09045	COG0583	DNA-binding transcription factor activity
CU111_RS09050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CU111_RS09055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CU111_RS09060	COG3344	reverse transcriptase
CU111_RS09075	COG0859	PFAM glycosyl transferase family 9
CU111_RS09080	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CU111_RS09090	COG2207	Transcriptional regulator
CU111_RS09095	COG2807	transmembrane transport
CU111_RS09100	COG0504	CTP synthase activity
CU111_RS09105	COG1683	Conserved Protein
CU111_RS09110	COG3189	MarR family transcriptional regulator
CU111_RS09115	COG3042	response to heat
CU111_RS09250	COG4695	Portal protein
CU111_RS09280	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CU111_RS09325	COG4974	Belongs to the 'phage' integrase family
CU111_RS09330	COG2199	diguanylate cyclase activity
CU111_RS09330	COG2203	Gaf domain
CU111_RS09350	COG3182	Iron-regulated membrane protein
CU111_RS09360	COG1560	Kdo2-lipid A biosynthetic process
CU111_RS09375	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CU111_RS09380	COG3706	GGDEF domain
CU111_RS09385	COG0583	DNA-binding transcription factor activity
CU111_RS09390	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CU111_RS09415	COG1294	oxidase, subunit
CU111_RS09420	COG1271	oxidase subunit
CU111_RS09425	COG3546	catalase activity
CU111_RS09430	COG3685	Protein conserved in bacteria
CU111_RS09435	COG3685	Protein conserved in bacteria
CU111_RS09440	COG3729	General stress protein
CU111_RS09445	COG1063	alcohol dehydrogenase
CU111_RS09450	COG3813	Protein conserved in bacteria
CU111_RS09470	COG0640	Transcriptional regulator
CU111_RS09475	COG0538	isocitrate dehydrogenase activity
CU111_RS09500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CU111_RS09505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CU111_RS09510	COG3344	reverse transcriptase
CU111_RS09630	COG4695	Portal protein
CU111_RS09635	COG4626	Terminase
CU111_RS09635	COG1802	Transcriptional regulator
CU111_RS09680	COG3179	chitinase
CU111_RS09725	COG0484	heat shock protein binding
CU111_RS09730	COG1403	HNH endonuclease
CU111_RS09745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CU111_RS09755	COG4725	Belongs to the MT-A70-like family
CU111_RS09765	COG1802	Transcriptional regulator
CU111_RS09765	COG4626	Terminase
CU111_RS09805	COG5532	Uncharacterized conserved protein (DUF2303)
CU111_RS09810	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CU111_RS09845	COG0582	viral genome integration into host DNA
CU111_RS09850	COG0538	isocitrate dehydrogenase activity
CU111_RS09855	COG1187	pseudouridine synthase activity
CU111_RS09875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CU111_RS09895	COG2205	protein histidine kinase activity
CU111_RS09900	COG2850	peptidyl-arginine hydroxylation
CU111_RS09920	COG1177	transmembrane transport
CU111_RS09935	COG0318	PFAM AMP-dependent synthetase and ligase
CU111_RS09940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CU111_RS09945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CU111_RS09950	COG0698	ribose 5-phosphate isomerase
CU111_RS09965	COG3395	kinase activity
CU111_RS09980	COG2390	Transcriptional regulator
CU111_RS09990	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CU111_RS10000	COG4591	ABC-type transport system involved in lipoprotein release permease component
CU111_RS10010	COG4591	ABC-type transport system involved in lipoprotein release permease component
CU111_RS10020	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CU111_RS10025	COG1388	LysM domain
CU111_RS10025	COG1376	ErfK ybiS ycfS ynhG family protein
CU111_RS10035	COG1309	transcriptional regulator
CU111_RS10045	COG3134	Outer membrane lipoprotein
CU111_RS10050	COG1252	NADH dehydrogenase
CU111_RS10075	COG5633	Lipoprotein
CU111_RS10080	COG0537	adenosine 5'-monophosphoramidase activity
CU111_RS10090	COG0084	hydrolase, TatD family'
CU111_RS10095	COG0470	DNA polymerase III
CU111_RS10105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CU111_RS10110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CU111_RS10115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CU111_RS10130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CU111_RS10150	COG1399	metal-binding, possibly nucleic acid-binding protein
CU111_RS10170	COG1530	ribonuclease E activity
CU111_RS10175	COG0583	DNA-binding transcription factor activity
CU111_RS10180	COG2814	Major facilitator Superfamily
CU111_RS10200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CU111_RS10250	COG1560	Kdo2-lipid A biosynthetic process
CU111_RS10270	COG5645	(Lipo)protein
CU111_RS10310	COG3381	protein complex oligomerization
CU111_RS10335	COG0583	DNA-binding transcription factor activity
CU111_RS10345	COG1335	isochorismatase
CU111_RS10355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CU111_RS10360	COG1702	phosphate starvation-inducible protein PhoH
CU111_RS10380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CU111_RS10390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CU111_RS10410	COG1309	transcriptional regulator
CU111_RS10445	COG2233	PERMEase
CU111_RS10460	COG3729	General stress protein
CU111_RS10485	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS10500	COG0531	amino acid
CU111_RS10510	COG0174	glutamine synthetase
CU111_RS10515	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CU111_RS10520	COG1396	sequence-specific DNA binding
CU111_RS10520	COG1917	Cupin 2, conserved barrel domain protein
CU111_RS10525	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS10530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CU111_RS10535	COG0583	DNA-binding transcription factor activity
CU111_RS10540	COG0473	3-isopropylmalate dehydrogenase activity
CU111_RS10545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CU111_RS10550	COG4638	Rieske (2fe-2S)
CU111_RS10555	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS10560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CU111_RS10565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS10565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS10565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CU111_RS10570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU111_RS10575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU111_RS10580	COG1882	Formate acetyltransferase
CU111_RS10585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CU111_RS10590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU111_RS10600	COG2207	Transcriptional regulator
CU111_RS10605	COG3706	GGDEF domain
CU111_RS10630	COG2200	EAL domain
CU111_RS10640	COG0058	SHG alpha-glucan phosphorylase activity
CU111_RS10655	COG0670	Belongs to the BI1 family
CU111_RS10670	COG2207	Transcriptional regulator
CU111_RS10675	COG1881	PFAM PEBP family protein
CU111_RS10690	COG1832	CoA-binding protein
CU111_RS10700	COG0210	DNA helicase
CU111_RS10705	COG3304	Inner membrane component domain
CU111_RS10710	COG1289	transmembrane transporter activity
CU111_RS10715	COG3070	regulator of competence-specific genes
CU111_RS10730	COG3344	reverse transcriptase
CU111_RS10755	COG1067	ATP-dependent peptidase activity
CU111_RS10765	COG3130	regulation of translation
CU111_RS10775	COG3009	Protein conserved in bacteria
CU111_RS10780	COG3008	intermembrane lipid transfer
CU111_RS10780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CU111_RS10785	COG2995	paraquat-inducible protein a
CU111_RS10790	COG0488	(ABC) transporter
CU111_RS10800	COG3217	Mosc domain protein beta barrel domain protein
CU111_RS10800	COG0633	Ferredoxin
CU111_RS10815	COG0431	NADPH-dependent FMN reductase
CU111_RS10820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CU111_RS10825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CU111_RS10830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CU111_RS10840	COG0308	aminopeptidase N
CU111_RS10855	COG1473	amidohydrolase
CU111_RS10865	COG0814	amino acid
CU111_RS10875	COG1522	sequence-specific DNA binding
CU111_RS10885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CU111_RS10890	COG1448	Aminotransferase
CU111_RS10895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CU111_RS10900	COG3108	Peptidase M15
CU111_RS10910	COG2989	Protein conserved in bacteria
CU111_RS10920	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CU111_RS10930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CU111_RS10935	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CU111_RS10940	COG3173	Aminoglycoside phosphotransferase
CU111_RS10955	COG3214	Protein conserved in bacteria
CU111_RS10970	COG0658	competence protein
CU111_RS10970	COG2333	competence protein COMEC
CU111_RS10980	COG0539	negative regulation of cytoplasmic translation
CU111_RS11000	COG2323	membrane
CU111_RS11005	COG1944	ATP diphosphatase activity
CU111_RS11010	COG2116	formate transmembrane transporter activity
CU111_RS11015	COG1882	Formate acetyltransferase
CU111_RS11020	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CU111_RS11025	COG0477	Major facilitator Superfamily
CU111_RS11035	COG3302	dmso reductase anchor subunit
CU111_RS11040	COG0437	4 iron, 4 sulfur cluster binding
CU111_RS11045	COG0243	molybdopterin cofactor binding
CU111_RS11055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CU111_RS11065	COG1178	ABC-type Fe3 transport system permease component
CU111_RS11065	COG1674	ftsk spoiiie
CU111_RS11075	COG0492	ferredoxin-NADP+ reductase activity
CU111_RS11080	COG4988	ABC transporter
CU111_RS11085	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CU111_RS11100	COG0542	response to heat
CU111_RS11110	COG1278	Cold shock
CU111_RS11125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU111_RS11130	COG3593	DNA synthesis involved in DNA repair
CU111_RS11140	COG2431	L-lysine efflux transmembrane transporter activity
CU111_RS11150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CU111_RS11160	COG0028	Belongs to the TPP enzyme family
CU111_RS11165	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CU111_RS11170	COG0702	epimerase
CU111_RS11175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CU111_RS11180	COG3023	N-Acetylmuramoyl-L-alanine amidase
CU111_RS11185	COG4251	negative regulation of phosphorylation
CU111_RS11185	COG3706	GGDEF domain
CU111_RS11185	COG5001	Diguanylate cyclase
CU111_RS11185	COG2203	Gaf domain
CU111_RS11200	COG1126	abc transporter atp-binding protein
CU111_RS11205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU111_RS11210	COG4215	(ABC) transporter
CU111_RS11215	COG4160	amino acid transport
CU111_RS11220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU111_RS11225	COG5002	protein histidine kinase activity
CU111_RS11230	COG0745	RESPONSE REGULATOR receiver
CU111_RS11245	COG1177	transmembrane transport
CU111_RS11250	COG1176	ABC-type spermidine putrescine transport system, permease component I
CU111_RS11255	COG3842	ATPase activity
CU111_RS11260	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CU111_RS11275	COG0778	Nitroreductase
CU111_RS11300	COG3226	Transcriptional regulator
CU111_RS11305	COG0738	Major facilitator superfamily
CU111_RS11310	COG0561	phosphatase activity
CU111_RS11315	COG2814	Major facilitator Superfamily
CU111_RS11325	COG0671	phosphoesterase, PA-phosphatase related
CU111_RS11330	COG1349	DNA-binding transcription factor activity
CU111_RS11335	COG1686	Belongs to the peptidase S11 family
CU111_RS11340	COG0625	glutathione transferase activity
CU111_RS11345	COG2133	pyrroloquinoline quinone binding
CU111_RS11355	COG2223	nitrite transmembrane transporter activity
CU111_RS11380	COG0747	negative chemotaxis
CU111_RS11395	COG0303	'Molybdopterin
CU111_RS11400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CU111_RS11405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CU111_RS11410	COG1882	Formate acetyltransferase
CU111_RS11415	COG0561	phosphatase activity
CU111_RS11425	COG1609	Transcriptional regulator
CU111_RS11430	COG2271	Major facilitator Superfamily
CU111_RS11445	COG0488	(ABC) transporter
CU111_RS11450	COG2365	Tyrosine phosphatase family
CU111_RS11455	COG1376	ErfK ybiS ycfS ynhG family protein
CU111_RS11460	COG2188	Transcriptional regulator
CU111_RS11465	COG2723	6-phospho-beta-galactosidase activity
CU111_RS11470	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CU111_RS11485	COG2194	sulfuric ester hydrolase activity
CU111_RS11490	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CU111_RS11505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU111_RS11510	COG0765	amino acid transport
CU111_RS11515	COG1126	abc transporter atp-binding protein
CU111_RS11520	COG0668	transmembrane transport
CU111_RS11530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CU111_RS11540	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CU111_RS11550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CU111_RS11555	COG1199	ATP-dependent helicase activity
CU111_RS11560	COG0513	Belongs to the DEAD box helicase family
CU111_RS11565	COG3958	Transketolase
CU111_RS11570	COG3959	Transketolase, thiamine diphosphate binding domain
CU111_RS11575	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS11580	COG2271	Major facilitator Superfamily
CU111_RS11585	COG0583	DNA-binding transcription factor activity
CU111_RS11590	COG1309	transcriptional regulator
CU111_RS11595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU111_RS11600	COG1131	(ABC) transporter
CU111_RS11605	COG0842	Transport permease protein
CU111_RS11610	COG0842	Transport permease protein
CU111_RS11625	COG3568	Endonuclease Exonuclease Phosphatase
CU111_RS11630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CU111_RS11635	COG0392	lysyltransferase activity
CU111_RS11655	COG0670	Belongs to the BI1 family
CU111_RS11660	COG0314	molybdopterin synthase activity
CU111_RS11665	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CU111_RS11675	COG0521	Mo-molybdopterin cofactor biosynthetic process
CU111_RS11700	COG0745	RESPONSE REGULATOR receiver
CU111_RS11705	COG0642	Histidine kinase
CU111_RS11740	COG2226	methyltransferase
CU111_RS11760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CU111_RS11765	COG1881	PFAM PEBP family protein
CU111_RS11805	COG4677	pectinesterase activity
CU111_RS11815	COG0589	response to stress
CU111_RS11820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU111_RS11855	COG0789	Transcriptional regulator
CU111_RS11860	COG2200	EAL domain
CU111_RS11885	COG0561	phosphatase activity
CU111_RS11895	COG4149	molybdate abc transporter
CU111_RS11900	COG0725	ABC transporter, periplasmic molybdate-binding protein
CU111_RS11910	COG2005	Transcriptional regulator
CU111_RS11910	COG3585	molybdate ion transport
CU111_RS11915	COG1119	ATPase activity
CU111_RS11925	COG1085	galactose-1-phosphate uridylyltransferase
CU111_RS11935	COG2017	converts alpha-aldose to the beta-anomer
CU111_RS11945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CU111_RS11960	COG3201	nicotinamide mononucleotide transporter
CU111_RS11965	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CU111_RS12010	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CU111_RS12015	COG2885	chlorophyll binding
CU111_RS12025	COG3064	Membrane
CU111_RS12030	COG0848	biopolymer transport protein
CU111_RS12035	COG0811	peptide transport
CU111_RS12040	COG0824	Thioesterase
CU111_RS12045	COG3790	cyd operon protein YbgE
CU111_RS12050	COG4890	Cyd operon protein YbgT
CU111_RS12055	COG1294	oxidase, subunit
CU111_RS12060	COG1271	oxidase subunit
CU111_RS12070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CU111_RS12080	COG0508	dehydrogenase complex catalyzes the overall conversion of
CU111_RS12085	COG0567	Dehydrogenase, E1 component
CU111_RS12090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CU111_RS12095	COG1053	succinate dehydrogenase
CU111_RS12100	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CU111_RS12105	COG2009	succinate dehydrogenase
CU111_RS12150	COG1984	allophanate hydrolase subunit 2
CU111_RS12155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CU111_RS12170	COG0415	Belongs to the DNA photolyase family
CU111_RS12200	COG2205	protein histidine kinase activity
CU111_RS12205	COG0745	RESPONSE REGULATOR receiver
CU111_RS12215	COG0033	Phosphoglucomutase
CU111_RS12225	COG0596	Alpha beta hydrolase
CU111_RS12240	COG0735	belongs to the Fur family
CU111_RS12285	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CU111_RS12290	COG1940	carbohydrate kinase activity
CU111_RS12290	COG1846	Transcriptional regulator
CU111_RS12295	COG0647	UMP catabolic process
CU111_RS12300	COG0367	asparagine synthase
CU111_RS12345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CU111_RS12355	COG1702	phosphate starvation-inducible protein PhoH
CU111_RS12380	COG0765	amino acid transport
CU111_RS12385	COG0765	amino acid transport
CU111_RS12390	COG1126	abc transporter atp-binding protein
CU111_RS12410	COG2888	peptidyl-tyrosine sulfation
CU111_RS12425	COG1466	dna polymerase III delta subunit
CU111_RS12445	COG0799	negative regulation of ribosome biogenesis
CU111_RS12455	COG0768	penicillin binding
CU111_RS12460	COG0772	Belongs to the SEDS family
CU111_RS12465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CU111_RS12470	COG1686	Belongs to the peptidase S11 family
CU111_RS12485	COG0583	DNA-binding transcription factor activity
CU111_RS12495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CU111_RS12500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CU111_RS12520	COG3069	C4-dicarboxylate transmembrane transporter activity
CU111_RS12525	COG3719	Belongs to the RNase T2 family
CU111_RS12530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CU111_RS12550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CU111_RS12555	COG0583	DNA-binding transcription factor activity
CU111_RS12560	COG3969	phosphoadenosine phosphosulfate
CU111_RS12565	COG1475	DNA binding
CU111_RS12570	COG0436	Aminotransferase
CU111_RS12595	COG1129	ABC transporter
CU111_RS12600	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU111_RS12605	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU111_RS12615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CU111_RS12630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CU111_RS12640	COG0402	S-adenosylhomocysteine deaminase activity
CU111_RS12650	COG0483	inositol monophosphate 1-phosphatase activity
CU111_RS12655	COG2271	Major facilitator Superfamily
CU111_RS12685	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU111_RS12690	COG1129	ABC transporter
CU111_RS12695	COG0371	Dehydrogenase
CU111_RS12700	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS12715	COG2879	small protein
CU111_RS12720	COG1966	Carbon starvation protein
CU111_RS12730	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS12735	COG3433	isochorismatase activity
CU111_RS12735	COG1535	isochorismatase
CU111_RS12740	COG1021	2,3-dihydroxybenzoate-AMP ligase
CU111_RS12745	COG1169	isochorismate synthase
CU111_RS12750	COG4592	Periplasmic binding protein
CU111_RS12760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU111_RS12765	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU111_RS12770	COG1120	ATPase activity
CU111_RS12775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CU111_RS12775	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CU111_RS12785	COG2382	esterase
CU111_RS12790	COG4771	TonB-dependent receptor
CU111_RS12795	COG2977	Belongs to the P-Pant transferase superfamily
CU111_RS12800	COG3958	Transketolase
CU111_RS12805	COG3959	Transketolase, thiamine diphosphate binding domain
CU111_RS12815	COG2390	Transcriptional regulator
CU111_RS12820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CU111_RS12825	COG1879	ABC-type sugar transport system periplasmic component
CU111_RS12850	COG1129	ABC transporter
CU111_RS12865	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS12875	COG0583	DNA-binding transcription factor activity
CU111_RS12880	COG0668	transmembrane transport
CU111_RS12890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CU111_RS12920	COG0747	negative chemotaxis
CU111_RS12925	COG0601	transmembrane transport
CU111_RS12930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU111_RS12935	COG0444	Belongs to the ABC transporter superfamily
CU111_RS12940	COG4608	Belongs to the ABC transporter superfamily
CU111_RS12955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CU111_RS12960	COG4221	oxidoreductase activity
CU111_RS12970	COG4215	(ABC) transporter
CU111_RS12980	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CU111_RS12995	COG0697	spore germination
CU111_RS13005	COG3698	Phosphodiester glycosidase
CU111_RS13050	COG2315	Protein conserved in bacteria
CU111_RS13055	COG0778	Nitroreductase
CU111_RS13085	COG0477	Major facilitator Superfamily
CU111_RS13090	COG0668	transmembrane transport
CU111_RS13095	COG1609	Transcriptional regulator
CU111_RS13105	COG0673	inositol 2-dehydrogenase activity
CU111_RS13115	COG2211	Major facilitator Superfamily
CU111_RS13120	COG1113	amino acid transport
CU111_RS13135	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS13140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CU111_RS13150	COG0531	amino acid
CU111_RS13165	COG4680	protein conserved in bacteria
CU111_RS13220	COG0667	Aldo Keto reductase
CU111_RS13225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU111_RS13230	COG1473	amidohydrolase
CU111_RS13250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU111_RS13255	COG1120	ATPase activity
CU111_RS13260	COG1566	PFAM secretion protein HlyD family protein
CU111_RS13305	COG4211	Belongs to the binding-protein-dependent transport system permease family
CU111_RS13310	COG1129	ABC transporter
CU111_RS13325	COG0673	inositol 2-dehydrogenase activity
CU111_RS13340	COG0673	inositol 2-dehydrogenase activity
CU111_RS13360	COG3104	oligopeptide transport
CU111_RS13365	COG1982	Orn Lys Arg decarboxylase major
CU111_RS13370	COG0531	amino acid
CU111_RS13375	COG3710	Transcriptional regulator
CU111_RS13385	COG1560	Kdo2-lipid A biosynthetic process
CU111_RS13420	COG3039	Transposase
CU111_RS13495	COG1196	nuclear chromosome segregation
CU111_RS13495	COG0741	lytic transglycosylase activity
CU111_RS13495	COG0739	heme binding
CU111_RS13570	COG5410	chromosome segregation
CU111_RS13595	COG3772	lysozyme
CU111_RS13785	COG0582	viral genome integration into host DNA
CU111_RS13805	COG2501	S4 domain
CU111_RS13815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CU111_RS13835	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CU111_RS13840	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CU111_RS13855	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CU111_RS13860	COG4181	ATPase activity
CU111_RS13865	COG2755	lipolytic protein G-D-S-L family
CU111_RS13870	COG0300	oxidoreductase activity
CU111_RS13875	COG3118	belongs to the thioredoxin family
CU111_RS13885	COG0390	transport system, permease component
CU111_RS13890	COG4619	ABC transporter
CU111_RS13895	COG0330	HflC and HflK could
CU111_RS13900	COG1585	Membrane protein implicated in regulation of membrane protease activity
CU111_RS13920	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CU111_RS13930	COG2223	nitrite transmembrane transporter activity
CU111_RS13935	COG4651	solute:proton antiporter activity
CU111_RS13935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CU111_RS13940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU111_RS13985	COG2832	Protein of unknown function (DUF454)
CU111_RS13990	COG3923	Primosomal replication protein n
CU111_RS14005	COG1196	nuclear chromosome segregation
CU111_RS14005	COG3264	Mechanosensitive ion channel
CU111_RS14010	COG1309	transcriptional regulator
CU111_RS14015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU111_RS14020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CU111_RS14035	COG0110	maltose O-acetyltransferase activity
CU111_RS14080	COG1874	Beta-galactosidase
CU111_RS14085	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CU111_RS14090	COG3833	ABC-type maltose transport systems, permease component
CU111_RS14095	COG1175	transmembrane transport
CU111_RS14100	COG2182	Extracellular solute-binding protein
CU111_RS14125	COG2364	Membrane
CU111_RS14155	COG3695	enzyme binding
CU111_RS14160	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CU111_RS14165	COG1946	Acyl-CoA thioesterase
CU111_RS14170	COG0004	ammonium transporteR
CU111_RS14175	COG0347	Belongs to the P(II) protein family
CU111_RS14180	COG1132	(ABC) transporter
CU111_RS14185	COG1132	(ABC) transporter
CU111_RS14190	COG1522	sequence-specific DNA binding
CU111_RS14205	COG4533	DNA binding
CU111_RS14215	COG0824	Thioesterase
CU111_RS14220	COG1555	photosystem II stabilization
CU111_RS14225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CU111_RS14230	COG0776	regulation of translation
CU111_RS14235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CU111_RS14265	COG0271	Belongs to the BolA IbaG family
CU111_RS14270	COG3056	Lipoprotein
CU111_RS14275	COG2223	nitrite transmembrane transporter activity
CU111_RS14280	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CU111_RS14285	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CU111_RS14290	COG1845	cytochrome c oxidase, subunit III
CU111_RS14295	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CU111_RS14310	COG1414	Transcriptional regulator
CU111_RS14315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CU111_RS14320	COG1053	succinate dehydrogenase
CU111_RS14330	COG1053	succinate dehydrogenase
CU111_RS14345	COG0673	inositol 2-dehydrogenase activity
CU111_RS14350	COG2814	Major facilitator Superfamily
CU111_RS14360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CU111_RS14365	COG0693	protein deglycase activity
CU111_RS14385	COG0142	geranyltranstransferase activity
CU111_RS14395	COG0667	Aldo Keto reductase
CU111_RS14400	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CU111_RS14420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CU111_RS14420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CU111_RS14430	COG4238	major outer membrane lipoprotein
CU111_RS14450	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CU111_RS14455	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CU111_RS14460	COG1862	Preprotein translocase
CU111_RS14480	COG0450	alkyl hydroperoxide reductase
CU111_RS14485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS14500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU111_RS14510	COG1228	amidohydrolase
CU111_RS14520	COG1335	isochorismatase
CU111_RS14525	COG0583	DNA-binding transcription factor activity
CU111_RS14530	COG0366	Alpha amylase catalytic
CU111_RS14555	COG0420	3'-5' exonuclease activity
CU111_RS14560	COG0419	ATPase involved in DNA repair
CU111_RS14565	COG1940	carbohydrate kinase activity
CU111_RS14580	COG4126	flavin adenine dinucleotide binding
CU111_RS14590	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CU111_RS14595	COG3416	Protein conserved in bacteria
CU111_RS14605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CU111_RS14615	COG1785	Belongs to the alkaline phosphatase family
CU111_RS14655	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CU111_RS14660	COG1335	isochorismatase
CU111_RS14665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CU111_RS14670	COG0113	porphobilinogen synthase activity
CU111_RS14675	COG1943	Transposase
CU111_RS14685	COG2175	clavaminate synthase activity
CU111_RS14690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CU111_RS14695	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CU111_RS14700	COG4521	taurine ABC transporter
CU111_RS14705	COG2040	homocysteine
CU111_RS14710	COG0833	amino acid
CU111_RS14720	COG4303	Ethanolamine ammonia lyase large subunit
CU111_RS14725	COG4302	ethanolamine ammonia-lyase activity
CU111_RS14765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU111_RS14770	COG1126	abc transporter atp-binding protein
CU111_RS14775	COG4597	amino acid ABC transporter
CU111_RS14780	COG0765	amino acid transport
CU111_RS14795	COG3188	usher protein
CU111_RS14820	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CU111_RS14830	COG3639	organic phosphonate transmembrane transporter activity
CU111_RS14855	COG0791	NLP P60 protein
CU111_RS15015	COG0582	viral genome integration into host DNA
CU111_RS15020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CU111_RS15055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CU111_RS15060	COG0022	dehydrogenase e1 component
CU111_RS15065	COG0508	dehydrogenase complex catalyzes the overall conversion of
CU111_RS15070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CU111_RS15095	COG1070	Carbohydrate kinase
CU111_RS15100	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS15105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CU111_RS15110	COG3775	system Galactitol-specific IIC component
CU111_RS15115	COG0625	glutathione transferase activity
CU111_RS15120	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CU111_RS15140	COG0579	oxidoreductase
CU111_RS15145	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS15150	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CU111_RS15155	COG1113	amino acid transport
CU111_RS15160	COG1802	Transcriptional regulator
CU111_RS15180	COG2195	Cleaves the N-terminal amino acid of tripeptides
CU111_RS15185	COG0454	-acetyltransferase
CU111_RS15200	COG2991	Protein conserved in bacteria
CU111_RS15215	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CU111_RS15220	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CU111_RS15240	COG3034	peptidoglycan biosynthetic process
CU111_RS15245	COG0121	glutamine amidotransferase
CU111_RS15255	COG1960	acyl-CoA dehydrogenase activity
CU111_RS15260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CU111_RS15270	COG0583	DNA-binding transcription factor activity
CU111_RS15285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CU111_RS15295	COG2226	methyltransferase
CU111_RS15305	COG0741	lytic transglycosylase activity
CU111_RS15305	COG1388	LysM domain
CU111_RS15310	COG2226	methyltransferase
CU111_RS15320	COG2814	Major facilitator Superfamily
CU111_RS15325	COG0583	DNA-binding transcription factor activity
CU111_RS15330	COG0656	L-ascorbic acid biosynthetic process
CU111_RS15370	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CU111_RS15380	COG2011	ABC-type metal ion transport system permease component
CU111_RS15385	COG1464	Belongs to the NlpA lipoprotein family
CU111_RS15395	COG1720	tRNA m6t6A37 methyltransferase activity
CU111_RS15405	COG0791	NLP P60 protein
CU111_RS15410	COG3015	lipoprotein NlpE involved in copper resistance
CU111_RS15415	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CU111_RS15430	COG4568	rho-dependent transcription termination
CU111_RS15440	COG0346	lactoylglutathione lyase activity
CU111_RS15445	COG1982	Orn Lys Arg decarboxylase major
CU111_RS15455	COG0587	DNA-directed DNA polymerase activity
CU111_RS15485	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CU111_RS15495	COG0750	zinc metalloprotease
CU111_RS15500	COG0575	Belongs to the CDS family
CU111_RS15515	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CU111_RS15540	COG0024	Methionine aminopeptidase
CU111_RS15545	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CU111_RS15560	COG3835	regulator
CU111_RS15565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CU111_RS15585	COG2860	membrane
CU111_RS15605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU111_RS15610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CU111_RS15615	COG1120	ATPase activity
CU111_RS15620	COG4774	siderophore transport
CU111_RS15625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CU111_RS15715	COG1643	Atp-dependent helicase
CU111_RS15720	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CU111_RS15740	COG0617	tRNA 3'-terminal CCA addition
CU111_RS15745	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CU111_RS15765	COG0726	polysaccharide deacetylase
CU111_RS15770	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS15775	COG0842	Transport permease protein
CU111_RS15780	COG1131	(ABC) transporter
CU111_RS15785	COG0288	reversible hydration of carbon dioxide
CU111_RS15795	COG4993	Dehydrogenase
CU111_RS15800	COG2132	Multicopper oxidase
CU111_RS15845	COG3064	Membrane
CU111_RS15860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CU111_RS15865	COG0508	dehydrogenase complex catalyzes the overall conversion of
CU111_RS15870	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CU111_RS15875	COG2186	Transcriptional regulator
CU111_RS15880	COG1113	amino acid transport
CU111_RS15885	COG2211	Major facilitator Superfamily
CU111_RS15890	COG3940	Belongs to the glycosyl hydrolase 43 family
CU111_RS15895	COG3725	Membrane protein required for beta-lactamase induction
CU111_RS15900	COG3023	N-Acetylmuramoyl-L-alanine amidase
CU111_RS15910	COG4969	Belongs to the N-Me-Phe pilin family
CU111_RS15915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CU111_RS15920	COG1459	type II secretion system
CU111_RS15945	COG0494	nUDIX hydrolase
CU111_RS15965	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CU111_RS15970	COG0849	cell division
CU111_RS15995	COG0772	Belongs to the SEDS family
CU111_RS16010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CU111_RS16015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CU111_RS16020	COG0768	penicillin binding
CU111_RS16045	COG1609	Transcriptional regulator
CU111_RS16055	COG0028	Belongs to the TPP enzyme family
CU111_RS16105	COG0738	Major facilitator superfamily
CU111_RS16115	COG0583	DNA-binding transcription factor activity
CU111_RS16120	COG2271	Major facilitator Superfamily
CU111_RS16125	COG2814	Major facilitator Superfamily
CU111_RS16145	COG1178	ABC-type Fe3 transport system permease component
CU111_RS16155	COG0586	Pfam SNARE associated Golgi protein
CU111_RS16175	COG0235	Class ii aldolase
CU111_RS16180	COG0417	DNA replication proofreading
CU111_RS16190	COG0564	pseudouridine synthase activity
CU111_RS16205	COG3493	citrate carrier protein
CU111_RS16220	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CU111_RS16225	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CU111_RS16235	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CU111_RS16285	COG0505	Belongs to the CarA family
CU111_RS16300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CU111_RS16325	COG1047	Peptidyl-prolyl cis-trans
CU111_RS16340	COG0196	riboflavin kinase activity
CU111_RS16360	COG0583	DNA-binding transcription factor activity
CU111_RS16385	COG4735	regulation of single-species biofilm formation
CU111_RS16390	COG1584	GPR1 FUN34 yaaH family protein
CU111_RS16400	COG0521	Mo-molybdopterin cofactor biosynthetic process
CU111_RS16405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CU111_RS16410	COG1115	amino acid carrier protein
CU111_RS16425	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CU111_RS16435	COG0460	homoserine dehydrogenase
CU111_RS16435	COG0527	aspartate kinase activity
CU111_RS16445	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CU111_RS16460	COG0745	RESPONSE REGULATOR receiver
CU111_RS16465	COG4452	Inner membrane protein CreD
CU111_RS16470	COG2205	protein histidine kinase activity
CU111_RS16475	COG0745	RESPONSE REGULATOR receiver
CU111_RS16480	COG3045	CreA protein
CU111_RS16485	COG3708	Transcriptional regulator
CU111_RS16485	COG2207	Transcriptional regulator
CU111_RS16505	COG0741	lytic transglycosylase activity
CU111_RS16515	COG0488	(ABC) transporter
CU111_RS16525	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CU111_RS16530	COG0560	Phosphoserine phosphatase
CU111_RS16540	COG3726	membrane protein affecting hemolysin expression
CU111_RS16570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CU111_RS16575	COG0084	hydrolase, TatD family'
CU111_RS16580	COG4667	esterase of the alpha-beta hydrolase superfamily
CU111_RS16590	COG2823	Periplasmic or secreted lipoprotein
CU111_RS16600	COG1011	Hydrolase
CU111_RS16605	COG0456	acetyltransferase
CU111_RS16610	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CU111_RS16640	COG3706	GGDEF domain
CU111_RS16645	COG4114	ferric iron reductase
CU111_RS16655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CU111_RS16660	COG2197	response regulator
CU111_RS16665	COG2197	response regulator
CU111_RS16685	COG2966	Psort location CytoplasmicMembrane, score
CU111_RS16700	COG1484	DNA-dependent DNA replication
CU111_RS16715	COG5464	transposase or invertase
CU111_RS16725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CU111_RS16730	COG3716	PTS system mannose fructose sorbose family IID component
CU111_RS16735	COG3715	PTS system
CU111_RS16750	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CU111_RS16750	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CU111_RS16755	COG1214	PFAM Peptidase M22, glycoprotease
CU111_RS16755	COG0456	acetyltransferase
CU111_RS16765	COG1737	Transcriptional regulator
CU111_RS16770	COG0800	Aldolase
CU111_RS16775	COG3734	2-keto-3-deoxy-galactonokinase
CU111_RS16790	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CU111_RS16820	COG1846	Transcriptional regulator
CU111_RS16825	COG0179	Fumarylacetoacetate (FAA) hydrolase
CU111_RS16835	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS16840	COG3384	dioxygenase
CU111_RS16850	COG3971	2-oxopent-4-enoate hydratase activity
CU111_RS16870	COG2368	4-hydroxyphenylacetate
CU111_RS16875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CU111_RS16895	COG3210	domain, Protein
CU111_RS16910	COG3210	domain, Protein
CU111_RS16915	COG2831	hemolysin activation secretion protein
CU111_RS16920	COG1966	Carbon starvation protein
CU111_RS16925	COG2879	small protein
CU111_RS16930	COG0523	cobalamin synthesis protein
CU111_RS16940	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS16945	COG5464	transposase or invertase
CU111_RS16950	COG2207	Transcriptional regulator
CU111_RS16950	COG1917	Cupin 2, conserved barrel domain protein
CU111_RS16960	COG2733	membrane
CU111_RS16975	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CU111_RS16980	COG1924	4 iron, 4 sulfur cluster binding
CU111_RS16995	COG1566	PFAM secretion protein HlyD family protein
CU111_RS17005	COG5457	Domain of unknown function (DUF1127)
CU111_RS17010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CU111_RS17020	COG0583	DNA-binding transcription factor activity
CU111_RS17025	COG2249	NAD(P)H dehydrogenase (quinone) activity
CU111_RS17035	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU111_RS17040	COG1129	ABC transporter
CU111_RS17045	COG1879	ABC-type sugar transport system periplasmic component
CU111_RS17055	COG3706	GGDEF domain
CU111_RS17060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU111_RS17065	COG0842	Transport permease protein
CU111_RS17065	COG1129	ABC transporter
CU111_RS17070	COG0842	Transport permease protein
CU111_RS17105	COG2850	peptidyl-arginine hydroxylation
CU111_RS17120	COG5002	protein histidine kinase activity
CU111_RS17125	COG0745	RESPONSE REGULATOR receiver
CU111_RS17135	COG1538	Outer membrane efflux protein
CU111_RS17140	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU111_RS17145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU111_RS17150	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CU111_RS17160	COG3040	lipid binding
CU111_RS17165	COG0789	Transcriptional regulator
CU111_RS17170	COG3631	Ketosteroid isomerase-related protein
CU111_RS17175	COG0300	oxidoreductase activity
CU111_RS17190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CU111_RS17210	COG3272	Protein of unknown function (DUF1722)
CU111_RS17215	COG4580	involved in the transport of maltose and maltodextrins
CU111_RS17220	COG2115	Belongs to the xylose isomerase family
CU111_RS17225	COG2211	Major facilitator Superfamily
CU111_RS17230	COG3507	Belongs to the glycosyl hydrolase 43 family
CU111_RS17250	COG1216	Glycosyl transferase, family 2
CU111_RS17330	COG2003	Belongs to the UPF0758 family
CU111_RS17355	COG4983	Phage plasmid primase, P4 family domain protein
CU111_RS17370	COG3311	Transcriptional regulator
CU111_RS17410	COG3436	PFAM IS66 Orf2 family protein
CU111_RS17415	COG4372	Transposase
CU111_RS17495	COG0582	viral genome integration into host DNA
CU111_RS17510	COG0288	reversible hydration of carbon dioxide
CU111_RS17515	COG0659	secondary active sulfate transmembrane transporter activity
CU111_RS17520	COG1064	alcohol dehydrogenase
CU111_RS17525	COG1175	transmembrane transport
CU111_RS17530	COG0395	ABC-type sugar transport system, permease component
CU111_RS17535	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CU111_RS17540	COG3842	ATPase activity
CU111_RS17555	COG1082	Xylose isomerase domain protein TIM barrel
CU111_RS17565	COG3962	Belongs to the TPP enzyme family
CU111_RS17570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU111_RS17575	COG1737	Transcriptional regulator
CU111_RS17575	COG0837	glucose binding
CU111_RS17600	COG3718	enzyme involved in inositol metabolism
CU111_RS17615	COG0433	COG0433 Predicted ATPase
CU111_RS17620	COG0795	lipopolysaccharide-transporting ATPase activity
CU111_RS17625	COG0795	lipopolysaccharide-transporting ATPase activity
CU111_RS17640	COG2927	DNA polymerase III (CHI subunit)
CU111_RS17645	COG0525	valine-tRNA ligase activity
CU111_RS17670	COG2731	YhcH YjgK YiaL family protein
CU111_RS17715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU111_RS17715	COG1263	PTS System
CU111_RS17720	COG0366	Alpha amylase catalytic
CU111_RS17725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU111_RS17730	COG1486	melibiose metabolic process
CU111_RS17750	COG0602	queuosine metabolic process
CU111_RS17755	COG2026	Addiction module toxin, RelE StbE family
CU111_RS17760	COG3077	Addiction module antitoxin, RelB DinJ family
CU111_RS17765	COG3711	transcriptional antiterminator
CU111_RS17765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS17770	COG2706	6-phosphogluconolactonase activity
CU111_RS17785	COG3964	amidohydrolase
CU111_RS17820	COG0312	modulator of DNA gyrase
CU111_RS17840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CU111_RS17850	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU111_RS17855	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU111_RS17860	COG1129	ABC transporter
CU111_RS17865	COG1879	ABC-type sugar transport system periplasmic component
CU111_RS17880	COG2105	PFAM AIG2 family protein
CU111_RS17885	COG2911	Protein conserved in bacteria
CU111_RS17890	COG0729	surface antigen
CU111_RS17900	COG1253	flavin adenine dinucleotide binding
CU111_RS17910	COG3039	Transposase
CU111_RS17935	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CU111_RS17950	COG1733	regulation of RNA biosynthetic process
CU111_RS17955	COG0702	epimerase
CU111_RS17965	COG0697	spore germination
CU111_RS17975	COG1113	amino acid transport
CU111_RS17980	COG0545	Peptidyl-prolyl cis-trans isomerase
CU111_RS17985	COG3061	Opacity-associated protein A
CU111_RS17995	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CU111_RS18000	COG2965	DNA replication, synthesis of RNA primer
CU111_RS18060	COG1073	alpha beta
CU111_RS18065	COG3650	response to hydrogen peroxide
CU111_RS18075	COG1960	acyl-CoA dehydrogenase activity
CU111_RS18080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CU111_RS18085	COG0557	exoribonuclease II activity
CU111_RS18100	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CU111_RS18110	COG0330	HflC and HflK could
CU111_RS18115	COG0330	HflC and HflK could
CU111_RS18120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CU111_RS18140	COG0860	N-Acetylmuramoyl-L-alanine amidase
CU111_RS18145	COG0802	atpase or kinase
CU111_RS18150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CU111_RS18150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CU111_RS18155	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CU111_RS18180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU111_RS18205	COG3264	Mechanosensitive ion channel
CU111_RS18205	COG1511	domain protein
CU111_RS18220	COG1053	succinate dehydrogenase
CU111_RS18225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CU111_RS18245	COG2076	Multidrug Resistance protein
CU111_RS18250	COG5510	response to toxic substance
CU111_RS18265	COG1509	lysine 2,3-aminomutase activity
CU111_RS18330	COG0531	amino acid
CU111_RS18335	COG3030	protein affecting phage T7 exclusion by the F plasmid
CU111_RS18345	COG1027	Aspartate ammonia-lyase
CU111_RS18350	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CU111_RS18365	COG1309	transcriptional regulator
CU111_RS18395	COG0457	Tetratricopeptide repeat
CU111_RS18400	COG0726	polysaccharide deacetylase
CU111_RS18400	COG1649	PFAM Uncharacterised BCR, COG1649
CU111_RS18405	COG1215	transferase activity, transferring glycosyl groups
CU111_RS18425	COG0861	Integral membrane protein TerC family
CU111_RS18455	COG1486	melibiose metabolic process
CU111_RS18465	COG2169	Transcriptional regulator
CU111_RS18480	COG2824	Alkylphosphonate utilization operon protein PhnA
CU111_RS18485	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CU111_RS18490	COG2188	Transcriptional regulator
CU111_RS18495	COG3624	Phosphonate C-P lyase system protein PhnG
CU111_RS18500	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CU111_RS18505	COG3626	phosphonate metabolism
CU111_RS18510	COG3627	carbon phosphorus lyase activity
CU111_RS18515	COG4107	phosphonate C-P lyase system protein PhnK
CU111_RS18520	COG4778	phosphonate C-P lyase system protein PhnL
CU111_RS18525	COG3454	Phosphonate metabolism
CU111_RS18535	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CU111_RS18545	COG0784	Response regulator, receiver
CU111_RS18545	COG4191	Histidine kinase
CU111_RS18550	COG1129	ABC transporter
CU111_RS18555	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU111_RS18590	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CU111_RS18595	COG1301	dicarboxylic acid transport
CU111_RS18605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CU111_RS18615	COG3162	membrane
CU111_RS18645	COG3539	Fimbrial protein
CU111_RS18650	COG1346	cytolysis
CU111_RS18655	COG1380	Effector of murein hydrolase LrgA
CU111_RS18660	COG0583	DNA-binding transcription factor activity
CU111_RS18665	COG0025	NhaP-type Na H and K H
CU111_RS18670	COG2252	PERMEase
CU111_RS18675	COG0625	glutathione transferase activity
CU111_RS18685	COG0789	Transcriptional regulator
CU111_RS18695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CU111_RS18730	COG1234	tRNA 3'-trailer cleavage
CU111_RS18735	COG1609	Transcriptional regulator
CU111_RS18740	COG0483	inositol monophosphate 1-phosphatase activity
CU111_RS18755	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CU111_RS18775	COG4771	TonB-dependent receptor
CU111_RS18780	COG0741	lytic transglycosylase activity
CU111_RS18800	COG2315	Protein conserved in bacteria
CU111_RS18805	COG0432	Pfam Uncharacterised protein family UPF0047
CU111_RS18820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CU111_RS18825	COG0305	Participates in initiation and elongation during chromosome replication
CU111_RS18840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CU111_RS18850	COG0735	belongs to the Fur family
CU111_RS18855	COG3237	CsbD-like
CU111_RS18860	COG0534	Mate efflux family protein
CU111_RS18870	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CU111_RS18945	COG0251	oxidation-reduction process
CU111_RS18955	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CU111_RS18975	COG0527	aspartate kinase activity
CU111_RS19025	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CU111_RS19035	COG0456	acetyltransferase
CU111_RS19080	COG0151	Belongs to the GarS family
CU111_RS19090	COG4191	Histidine kinase
CU111_RS19095	COG3678	ATP-independent chaperone mediated protein folding
CU111_RS19130	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CU111_RS19145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CU111_RS19150	COG2104	thiamine diphosphate biosynthetic process
CU111_RS19170	COG3706	GGDEF domain
CU111_RS19180	COG1447	Phosphotransferase system cellobiose-specific component IIA
CU111_RS19185	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CU111_RS19225	COG0250	Participates in transcription elongation, termination and antitermination
CU111_RS19275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CU111_RS19310	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CU111_RS19320	COG1739	Uncharacterized protein family UPF0029
CU111_RS19365	COG0805	protein transport
CU111_RS19385	COG3165	ubiquinone biosynthetic process from chorismate
CU111_RS19415	COG0583	DNA-binding transcription factor activity
CU111_RS19420	COG0697	spore germination
CU111_RS19425	COG0561	phosphatase activity
CU111_RS19430	COG2267	carboxylic ester hydrolase activity
CU111_RS19435	COG1280	lysine exporter protein (LysE YggA)
CU111_RS19445	COG1280	lysine exporter protein (LysE YggA)
CU111_RS19480	COG0210	DNA helicase
CU111_RS19485	COG1011	Hydrolase
CU111_RS19515	COG3072	Adenylate cyclase
CU111_RS19530	COG2959	enzyme of heme biosynthesis
CU111_RS19535	COG3071	HemY protein
CU111_RS19580	COG2244	polysaccharide biosynthetic process
CU111_RS19585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CU111_RS19590	COG0456	acetyltransferase
CU111_RS19595	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CU111_RS19600	COG1088	dTDP-glucose 4,6-dehydratase activity
CU111_RS19605	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CU111_RS19610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CU111_RS19620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CU111_RS19625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CU111_RS19635	COG3118	belongs to the thioredoxin family
CU111_RS19665	COG1811	Na channel or pump
CU111_RS19675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CU111_RS19680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CU111_RS19690	COG0583	DNA-binding transcription factor activity
CU111_RS19695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CU111_RS19710	COG3978	acetolactate synthase activity
CU111_RS19730	COG3085	chromosome segregation
CU111_RS19805	COG0583	DNA-binding transcription factor activity
CU111_RS19830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CU111_RS19845	COG3443	Belongs to the bacterial solute-binding protein 9 family
CU111_RS19850	COG2207	Transcriptional regulator
CU111_RS19860	COG0371	Dehydrogenase
CU111_RS19865	COG0697	spore germination
CU111_RS19875	COG0583	DNA-binding transcription factor activity
CU111_RS19885	COG0737	Belongs to the 5'-nucleotidase family
CU111_RS19895	COG0527	aspartate kinase activity
CU111_RS19895	COG0460	homoserine dehydrogenase
CU111_RS19900	COG0626	cystathionine gamma-synthase activity
CU111_RS19915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CU111_RS19920	COG1609	Transcriptional regulator
CU111_RS19925	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CU111_RS19940	COG1575	Belongs to the MenA family. Type 1 subfamily
CU111_RS19960	COG3678	ATP-independent chaperone mediated protein folding
CU111_RS19965	COG0745	RESPONSE REGULATOR receiver
CU111_RS19970	COG2205	protein histidine kinase activity
CU111_RS19975	COG2258	MOSC domain
CU111_RS19980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CU111_RS20025	COG1129	ABC transporter
CU111_RS20030	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU111_RS20035	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU111_RS20040	COG1454	alcohol dehydrogenase
CU111_RS20050	COG2211	Major facilitator Superfamily
CU111_RS20095	COG3383	formate dehydrogenase (NAD+) activity
CU111_RS20095	COG0243	molybdopterin cofactor binding
CU111_RS20100	COG0243	molybdopterin cofactor binding
CU111_RS20100	COG3383	formate dehydrogenase (NAD+) activity
CU111_RS20105	COG0437	4 iron, 4 sulfur cluster binding
CU111_RS20110	COG2864	formate dehydrogenase
CU111_RS20125	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CU111_RS20135	COG0456	acetyltransferase
CU111_RS20150	COG1011	Hydrolase
CU111_RS20170	COG3852	Histidine kinase
CU111_RS20180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CU111_RS20210	COG0204	Acyl-transferase
CU111_RS20220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CU111_RS20225	COG3084	Protein conserved in bacteria
CU111_RS20235	COG1763	Mo-molybdopterin cofactor biosynthetic process
CU111_RS20265	COG2186	Transcriptional regulator
CU111_RS20270	COG0477	Major facilitator Superfamily
CU111_RS20275	COG1609	Transcriptional regulator
CU111_RS20280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU111_RS20290	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU111_RS20295	COG1129	ABC transporter
CU111_RS20325	COG1522	sequence-specific DNA binding
CU111_RS20330	COG0716	FMN binding
CU111_RS20345	COG3312	ion transport
CU111_RS20395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CU111_RS20400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CU111_RS20405	COG0573	inorganic phosphate transmembrane transporter activity
CU111_RS20410	COG0581	inorganic phosphate transmembrane transporter activity
CU111_RS20415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CU111_RS20420	COG0704	Plays a role in the regulation of phosphate uptake
CU111_RS20435	COG2382	esterase
CU111_RS20440	COG0363	glucosamine-6-phosphate deaminase activity
CU111_RS20445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CU111_RS20455	COG2252	PERMEase
CU111_RS20460	COG0431	NADPH-dependent FMN reductase
CU111_RS20465	COG2091	lysine biosynthetic process via aminoadipic acid
CU111_RS20500	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CU111_RS20535	COG0187	DNA topoisomerase II activity
CU111_RS20540	COG0561	phosphatase activity
CU111_RS20555	COG2186	Transcriptional regulator
CU111_RS20560	COG3734	2-keto-3-deoxy-galactonokinase
CU111_RS20565	COG0800	Aldolase
CU111_RS20575	COG2271	Major facilitator Superfamily
CU111_RS20580	COG0823	Involved in the tonB-independent uptake of proteins
CU111_RS20585	COG5645	(Lipo)protein
CU111_RS20600	COG3645	SOS response
CU111_RS20610	COG2188	Transcriptional regulator
CU111_RS20625	COG2149	membrane
CU111_RS20645	COG2610	gluconate transmembrane transporter activity
CU111_RS20650	COG0583	DNA-binding transcription factor activity
CU111_RS20655	COG2814	Major facilitator Superfamily
CU111_RS20680	COG0028	Belongs to the TPP enzyme family
CU111_RS20685	COG0440	acetolactate synthase activity
CU111_RS20690	COG2197	response regulator
CU111_RS20700	COG2271	Major facilitator Superfamily
CU111_RS20745	COG2188	Transcriptional regulator
CU111_RS20770	COG4580	involved in the transport of maltose and maltodextrins
CU111_RS20775	COG1447	Phosphotransferase system cellobiose-specific component IIA
CU111_RS20780	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU111_RS20780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU111_RS20790	COG1609	Transcriptional regulator
CU111_RS20800	COG3384	dioxygenase
CU111_RS20805	COG0583	DNA-binding transcription factor activity
CU111_RS20810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CU111_RS20815	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CU111_RS20820	COG2828	Protein conserved in bacteria
CU111_RS20835	COG0697	spore germination
CU111_RS20840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU111_RS20840	COG1263	PTS System
CU111_RS20850	COG2814	Major facilitator Superfamily
CU111_RS20860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CU111_RS20895	COG0583	DNA-binding transcription factor activity
CU111_RS20920	COG1464	Belongs to the NlpA lipoprotein family
CU111_RS20935	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CU111_RS20945	COG1064	alcohol dehydrogenase
CU111_RS20975	COG2211	Major facilitator Superfamily
CU111_RS20980	COG1501	Belongs to the glycosyl hydrolase 31 family
CU111_RS20990	COG1486	melibiose metabolic process
CU111_RS20995	COG1263	PTS System
CU111_RS20995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU111_RS21000	COG2982	Protein involved in outer membrane biogenesis
CU111_RS21005	COG2233	PERMEase
CU111_RS21010	COG0786	glutamate:sodium symporter activity
CU111_RS21030	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CU111_RS21055	COG3152	Membrane
CU111_RS21065	COG1494	fructose-1,6-bisphosphatase
CU111_RS21070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CU111_RS21075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CU111_RS21080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CU111_RS21100	COG2860	membrane
CU111_RS21110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CU111_RS21110	COG2169	Transcriptional regulator
CU111_RS21115	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CU111_RS21120	COG1561	YicC-like family, N-terminal region
CU111_RS21140	COG1131	(ABC) transporter
CU111_RS21145	COG0842	Transport permease protein
CU111_RS21175	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CU111_RS21210	COG1519	Transferase
CU111_RS21215	COG1216	Glycosyl transferase, family 2
CU111_RS21220	COG0438	transferase activity, transferring glycosyl groups
CU111_RS21230	COG0859	PFAM glycosyl transferase family 9
CU111_RS21255	COG0859	PFAM glycosyl transferase family 9
CU111_RS21270	COG0156	8-amino-7-oxononanoate synthase activity
CU111_RS21280	COG0463	Glycosyl transferase, family 2
CU111_RS21285	COG2861	carbohydrate metabolic process
CU111_RS21290	COG4942	peptidase
CU111_RS21300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CU111_RS21305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CU111_RS21325	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CU111_RS21335	COG2186	Transcriptional regulator
CU111_RS21355	COG3722	fumarate hydratase activity
CU111_RS21375	COG0625	glutathione transferase activity
CU111_RS21385	COG3276	selenocysteine insertion sequence binding
CU111_RS21390	COG1414	Transcriptional regulator
CU111_RS21395	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CU111_RS21400	COG3977	Valine--pyruvate aminotransferase
CU111_RS21405	COG0366	Alpha amylase catalytic
CU111_RS21415	COG2992	FlgJ-related protein
CU111_RS21420	COG1609	Transcriptional regulator
CU111_RS21420	COG2207	Transcriptional regulator
CU111_RS21425	COG4214	carbohydrate transport
CU111_RS21435	COG4213	ABC transporter substrate-binding protein
CU111_RS21455	COG4682	membrane
CU111_RS21460	COG4682	membrane
CU111_RS21465	COG3274	enterobacterial common antigen metabolic process
CU111_RS21500	COG1278	Cold shock
CU111_RS21505	COG2944	sequence-specific DNA binding
CU111_RS21510	COG2814	Major facilitator Superfamily
CU111_RS21535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU111_RS21545	COG1609	Transcriptional regulator
CU111_RS21550	COG2885	chlorophyll binding
CU111_RS21555	COG0243	molybdopterin cofactor binding
CU111_RS21560	COG0456	acetyltransferase
CU111_RS21565	COG2818	Glycosylase
CU111_RS21570	COG5571	outer membrane autotransporter
CU111_RS21575	COG2223	nitrite transmembrane transporter activity
CU111_RS21610	COG0747	negative chemotaxis
CU111_RS21615	COG0601	transmembrane transport
CU111_RS21620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU111_RS21625	COG0444	Belongs to the ABC transporter superfamily
CU111_RS21630	COG4608	Belongs to the ABC transporter superfamily
CU111_RS21645	COG2894	cell division
CU111_RS21655	COG1215	transferase activity, transferring glycosyl groups
CU111_RS21660	COG0457	Tetratricopeptide repeat
CU111_RS21675	COG2194	sulfuric ester hydrolase activity
CU111_RS21705	COG1215	transferase activity, transferring glycosyl groups
CU111_RS21710	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CU111_RS21715	COG0457	Tetratricopeptide repeat
CU111_RS21715	COG3118	belongs to the thioredoxin family
CU111_RS21720	COG2200	EAL domain
CU111_RS21720	COG2199	diguanylate cyclase activity
CU111_RS21735	COG0612	Peptidase, M16
CU111_RS21750	COG2982	Protein involved in outer membrane biogenesis
CU111_RS21755	COG0477	Major facilitator Superfamily
CU111_RS21765	COG1295	ribonuclease BN
CU111_RS21770	COG0583	DNA-binding transcription factor activity
CU111_RS21775	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS21780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CU111_RS21790	COG1454	alcohol dehydrogenase
CU111_RS21800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CU111_RS21805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CU111_RS21830	COG0589	response to stress
CU111_RS21840	COG0306	phosphate transporter
CU111_RS21845	COG2081	HI0933 family
CU111_RS21850	COG2239	Acts as a magnesium transporter
CU111_RS21860	COG1124	(ABC) transporter
CU111_RS21870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU111_RS21875	COG0601	transmembrane transport
CU111_RS21880	COG0747	negative chemotaxis
CU111_RS21895	COG3479	Phenolic acid decarboxylase
CU111_RS21940	COG0477	Major facilitator Superfamily
CU111_RS21950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CU111_RS21965	COG3714	YhhN family
CU111_RS21975	COG3776	membrane
CU111_RS21980	COG0742	ribosomal rna small subunit methyltransferase
CU111_RS21985	COG0552	protein localization to endoplasmic reticulum
CU111_RS21990	COG2884	Cell division ATP-binding protein ftsE
CU111_RS21995	COG2177	Part of the ABC transporter FtsEX involved in
CU111_RS22010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CU111_RS22025	COG0683	leucine binding
CU111_RS22040	COG0683	leucine binding
CU111_RS22045	COG0559	Belongs to the binding-protein-dependent transport system permease family
CU111_RS22095	COG0584	glycerophosphoryl diester phosphodiesterase
CU111_RS22105	COG0405	Gamma-glutamyltransferase
CU111_RS22110	COG1247	-acetyltransferase
CU111_RS22120	COG0673	inositol 2-dehydrogenase activity
CU111_RS22125	COG1741	Belongs to the pirin family
CU111_RS22130	COG1609	Transcriptional regulator
CU111_RS22135	COG3265	gluconokinase activity
CU111_RS22140	COG2610	gluconate transmembrane transporter activity
CU111_RS22150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CU111_RS22175	COG0058	SHG alpha-glucan phosphorylase activity
CU111_RS22180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CU111_RS22195	COG1349	DNA-binding transcription factor activity
CU111_RS22210	COG0058	SHG alpha-glucan phosphorylase activity
CU111_RS22215	COG1640	4-alpha-glucanotransferase
CU111_RS22220	COG2610	gluconate transmembrane transporter activity
CU111_RS22230	COG1040	competence protein
CU111_RS22255	COG1918	ferrous iron import across plasma membrane
CU111_RS22260	COG2183	response to ionizing radiation
CU111_RS22265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CU111_RS22290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CU111_RS22295	COG1011	Hydrolase
CU111_RS22305	COG0494	nUDIX hydrolase
CU111_RS22310	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CU111_RS22335	COG4796	Type ii and iii secretion system protein
CU111_RS22355	COG3266	domain, Protein
CU111_RS22360	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CU111_RS22365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CU111_RS22390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CU111_RS22395	COG0402	S-adenosylhomocysteine deaminase activity
CU111_RS22400	COG0738	Major facilitator superfamily
CU111_RS22425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CU111_RS22430	COG1289	transmembrane transporter activity
CU111_RS22445	COG1765	OsmC-like protein
CU111_RS22450	COG3954	Phosphoribulokinase
CU111_RS22460	COG0429	hydrolase of the alpha beta-hydrolase fold
CU111_RS22470	COG0488	(ABC) transporter
CU111_RS22490	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CU111_RS22495	COG1047	Peptidyl-prolyl cis-trans
CU111_RS22505	COG0545	Peptidyl-prolyl cis-trans isomerase
CU111_RS22510	COG2964	Protein conserved in bacteria
CU111_RS22570	COG0051	transcription antitermination factor activity, RNA binding
CU111_RS22595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CU111_RS22610	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CU111_RS22675	COG0201	protein transport
CU111_RS22700	COG0202	RNA polymerase activity
CU111_RS22715	COG0789	Transcriptional regulator
CU111_RS22720	COG3036	rescue of stalled ribosome
CU111_RS22750	COG0758	DNA mediated transformation
CU111_RS22760	COG0551	DNA topoisomerase type I activity
CU111_RS22780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CU111_RS22820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CU111_RS22825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU111_RS22830	COG1309	transcriptional regulator
CU111_RS22855	COG4145	pantothenate transmembrane transporter activity
CU111_RS22860	COG3924	membrane
CU111_RS22865	COG0439	Biotin carboxylase
CU111_RS22870	COG0511	ligase activity, forming carbon-carbon bonds
CU111_RS22900	COG2200	EAL domain
CU111_RS22900	COG2199	diguanylate cyclase activity
CU111_RS22910	COG1077	Cell shape determining protein MreB Mrl
CU111_RS22915	COG1792	Involved in formation and maintenance of cell shape
CU111_RS22920	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CU111_RS22930	COG1530	ribonuclease E activity
CU111_RS22935	COG3164	Protein of unknown function
CU111_RS22940	COG0312	modulator of DNA gyrase
CU111_RS22945	COG0583	DNA-binding transcription factor activity
CU111_RS22960	COG1289	transmembrane transporter activity
CU111_RS22965	COG2732	(Barnase) inhibitor
CU111_RS23000	COG0471	metal ion transport
CU111_RS23005	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CU111_RS23010	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CU111_RS23035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CU111_RS23040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CU111_RS23045	COG3105	Protein conserved in bacteria
CU111_RS23050	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CU111_RS23070	COG0625	glutathione transferase activity
CU111_RS23075	COG2969	positive regulation of protein catabolic process
CU111_RS23085	COG0493	'glutamate synthase
CU111_RS23090	COG0067	glutamate synthase
CU111_RS23090	COG0069	glutamate synthase activity
CU111_RS23090	COG0070	glutamate synthase
CU111_RS23100	COG1242	4 iron, 4 sulfur cluster binding
CU111_RS23105	COG2271	Major facilitator Superfamily
CU111_RS23110	COG1063	alcohol dehydrogenase
CU111_RS23115	COG1312	Catalyzes the dehydration of D-mannonate
CU111_RS23120	COG2198	Histidine kinase
CU111_RS23120	COG0784	Response regulator, receiver
CU111_RS23120	COG5002	protein histidine kinase activity
CU111_RS23125	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CU111_RS23130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CU111_RS23135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS23145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS23150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CU111_RS23155	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CU111_RS23160	COG1137	ATPase activity
CU111_RS23165	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CU111_RS23170	COG3117	lipopolysaccharide transmembrane transporter activity
CU111_RS23175	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CU111_RS23185	COG0530	calcium, potassium:sodium antiporter activity
CU111_RS23195	COG1127	ABC transporter
CU111_RS23200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CU111_RS23205	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CU111_RS23210	COG2854	intermembrane phospholipid transfer
CU111_RS23215	COG3113	response to antibiotic
CU111_RS23220	COG5007	Belongs to the BolA IbaG family
CU111_RS23230	COG3423	Transcriptional regulator
CU111_RS23235	COG0142	geranyltranstransferase activity
CU111_RS23250	COG0697	spore germination
CU111_RS23260	COG2027	D-alanyl-D-alanine carboxypeptidase
CU111_RS23270	COG1534	Rna-binding protein
CU111_RS23280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CU111_RS23285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CU111_RS23295	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CU111_RS23335	COG0195	Participates in both transcription termination and antitermination
CU111_RS23385	COG0814	amino acid
CU111_RS23390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CU111_RS23395	COG0826	peptidase U32
CU111_RS23400	COG0826	peptidase U32
CU111_RS23405	COG3154	lipid carrier protein
CU111_RS23410	COG3153	acetyltransferase
CU111_RS23425	COG0693	protein deglycase activity
CU111_RS23430	COG0702	epimerase
CU111_RS23435	COG0701	Predicted permease
CU111_RS23440	COG2823	Periplasmic or secreted lipoprotein
CU111_RS23460	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CU111_RS23465	COG2721	sulfolactate sulfo-lyase activity
CU111_RS23470	COG2271	Major facilitator Superfamily
CU111_RS23480	COG2084	Dehydrogenase
CU111_RS23485	COG1929	Belongs to the glycerate kinase type-1 family
CU111_RS23505	COG1741	Belongs to the pirin family
CU111_RS23510	COG0583	DNA-binding transcription factor activity
CU111_RS23515	COG3152	Membrane
CU111_RS23520	COG0435	Glutathione S-transferase
CU111_RS23525	COG2259	Doxx family
CU111_RS23535	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CU111_RS23540	COG4575	ribosome binding
CU111_RS23545	COG1422	Protein of unknown function (DUF1090)
CU111_RS23555	COG0586	Pfam SNARE associated Golgi protein
CU111_RS23565	COG2186	Transcriptional regulator
CU111_RS23570	COG2271	Major facilitator Superfamily
CU111_RS23580	COG2721	sulfolactate sulfo-lyase activity
CU111_RS23595	COG0861	Integral membrane protein TerC family
CU111_RS23600	COG0673	inositol 2-dehydrogenase activity
CU111_RS23605	COG1451	nucleotide metabolic process
CU111_RS23625	COG1902	pentaerythritol trinitrate reductase activity
CU111_RS23625	COG0446	pyridine nucleotide-disulphide oxidoreductase
CU111_RS23680	COG1695	Transcriptional regulator
CU111_RS23685	COG2375	cellular response to nickel ion
CU111_RS23700	COG1461	Dihydroxyacetone kinase
CU111_RS23705	COG2376	Dihydroxyacetone kinase
CU111_RS23780	COG3247	response to pH
CU111_RS23790	COG0784	Response regulator, receiver
CU111_RS23790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU111_RS23790	COG2198	Histidine kinase
CU111_RS23790	COG2205	protein histidine kinase activity
CU111_RS23795	COG2197	response regulator
CU111_RS23835	COG3539	Fimbrial protein
CU111_RS23840	COG3121	Chaperone
CU111_RS23860	COG3539	Fimbrial protein
CU111_RS23865	COG3539	Fimbrial protein
CU111_RS23870	COG3539	Fimbrial protein
CU111_RS23875	COG2200	EAL domain
CU111_RS23905	COG4983	Phage plasmid primase, P4 family domain protein
CU111_RS23955	COG0210	DNA helicase
CU111_RS23975	COG3596	GTP binding
CU111_RS23985	COG2378	regulation of single-species biofilm formation
CU111_RS23990	COG3468	outer membrane autotransporter barrel domain protein
CU111_RS24005	COG2003	Belongs to the UPF0758 family
CU111_RS24040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CU111_RS24045	COG0358	DNA primase activity
CU111_RS24050	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CU111_RS24115	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CU111_RS24130	COG4991	sh3 domain protein
CU111_RS24135	COG3025	triphosphatase activity
CU111_RS24155	COG2960	long-chain fatty acid transporting porin activity
CU111_RS24170	COG3384	dioxygenase
CU111_RS24175	COG0754	glutathionylspermidine amidase activity
CU111_RS24190	COG0494	nUDIX hydrolase
CU111_RS24195	COG3151	Protein conserved in bacteria
CU111_RS24200	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CU111_RS24205	COG3150	esterase
CU111_RS24215	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CU111_RS24220	COG2249	NAD(P)H dehydrogenase (quinone) activity
CU111_RS24225	COG0642	Histidine kinase
CU111_RS24235	COG3111	PFAM Bacterial OB fold (BOF) protein
CU111_RS24240	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CU111_RS24245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CU111_RS24250	COG0204	Acyl-transferase
CU111_RS24255	COG2132	Multicopper oxidase
CU111_RS24260	COG1032	radical SAM domain protein
CU111_RS24270	COG0656	L-ascorbic acid biosynthetic process
CU111_RS24275	COG1979	alcohol dehydrogenase
CU111_RS24280	COG2207	Transcriptional regulator
CU111_RS24285	COG0586	Pfam SNARE associated Golgi protein
CU111_RS24290	COG0626	cystathionine gamma-synthase activity
CU111_RS24305	COG0848	biopolymer transport protein
CU111_RS24310	COG2211	Major facilitator Superfamily
CU111_RS24335	COG0625	glutathione transferase activity
CU111_RS24345	COG0754	glutathionylspermidine amidase activity
CU111_RS24350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CU111_RS24370	COG0583	DNA-binding transcription factor activity
CU111_RS24375	COG0626	cystathionine gamma-synthase activity
CU111_RS24390	COG3121	Chaperone
CU111_RS24405	COG3121	Chaperone
CU111_RS24410	COG3121	Chaperone
CU111_RS24415	COG3188	usher protein
CU111_RS24445	COG1811	Na channel or pump
CU111_RS24455	COG1982	Orn Lys Arg decarboxylase major
CU111_RS24460	COG2211	Major facilitator Superfamily
CU111_RS24475	COG1194	a g-specific adenine glycosylase
CU111_RS24485	COG3171	Protein conserved in bacteria
CU111_RS24495	COG4214	carbohydrate transport
CU111_RS24510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CU111_RS24525	COG0762	integral membrane protein
CU111_RS24530	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CU111_RS24535	COG2805	Type II/IV secretion system protein
CU111_RS24555	COG0189	ligase activity
CU111_RS24560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CU111_RS24565	COG2356	endonuclease I
CU111_RS24575	COG2814	Major facilitator Superfamily
CU111_RS24610	COG0501	Belongs to the peptidase M48B family
CU111_RS24615	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CU111_RS24630	COG0191	fructose-bisphosphate aldolase activity
CU111_RS24635	COG0668	transmembrane transport
CU111_RS24645	COG2968	Membrane
CU111_RS24660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CU111_RS24665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CU111_RS24685	COG0006	proline dipeptidase activity
CU111_RS24690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CU111_RS24695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CU111_RS24715	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS24720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CU111_RS24740	COG2723	6-phospho-beta-galactosidase activity
CU111_RS24745	COG1737	Transcriptional regulator
CU111_RS24755	COG1272	protein, Hemolysin III
CU111_RS24765	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CU111_RS24775	COG0716	FMN binding
CU111_RS24780	COG4974	Belongs to the 'phage' integrase family
CU111_RS24790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CU111_RS24810	COG1811	Na channel or pump
CU111_RS24820	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CU111_RS24825	COG0583	DNA-binding transcription factor activity
CU111_RS24830	COG4942	peptidase
CU111_RS24840	COG2814	Major facilitator Superfamily
CU111_RS24855	COG0667	Aldo Keto reductase
CU111_RS24895	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CU111_RS24900	COG1393	Belongs to the ArsC family
CU111_RS24915	COG1538	Outer membrane efflux protein
CU111_RS24920	COG1289	transmembrane transporter activity
CU111_RS24935	COG3592	Divergent 4Fe-4S mono-cluster
CU111_RS24940	COG2388	GCN5-related N-acetyl-transferase
CU111_RS24950	COG3539	Fimbrial protein
CU111_RS24955	COG3539	Fimbrial protein
CU111_RS24960	COG3539	Fimbrial protein
CU111_RS24965	COG3188	usher protein
CU111_RS24970	COG3121	Chaperone
CU111_RS24975	COG3539	Fimbrial protein
CU111_RS24985	COG4974	Belongs to the 'phage' integrase family
CU111_RS24990	COG0582	viral genome integration into host DNA
CU111_RS25000	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CU111_RS25005	COG1846	Transcriptional regulator
CU111_RS25010	COG0697	spore germination
CU111_RS25060	COG0667	Aldo Keto reductase
CU111_RS25065	COG0814	amino acid
CU111_RS25080	COG0183	Belongs to the thiolase family
CU111_RS25095	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS25100	COG2814	Major facilitator Superfamily
CU111_RS25130	COG3842	ATPase activity
CU111_RS25140	COG1175	transmembrane transport
CU111_RS25145	COG1917	Cupin 2, conserved barrel domain protein
CU111_RS25150	COG1794	racemase activity, acting on amino acids and derivatives
CU111_RS25155	COG0583	DNA-binding transcription factor activity
CU111_RS25165	COG1609	Transcriptional regulator
CU111_RS25170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU111_RS25175	COG2723	6-phospho-beta-galactosidase activity
CU111_RS25180	COG2186	Transcriptional regulator
CU111_RS25190	COG1609	Transcriptional regulator
CU111_RS25215	COG0667	Aldo Keto reductase
CU111_RS25225	COG0861	Integral membrane protein TerC family
CU111_RS25260	COG2165	general secretion pathway protein
CU111_RS25265	COG4795	General secretion pathway protein
CU111_RS25275	COG4967	type IV pilus modification protein PilV
CU111_RS25280	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CU111_RS25285	COG1025	Belongs to the peptidase M16 family
CU111_RS25290	COG1074	ATP-dependent DNA helicase activity
CU111_RS25295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CU111_RS25305	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CU111_RS25305	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CU111_RS25310	COG0860	N-Acetylmuramoyl-L-alanine amidase
CU111_RS25315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CU111_RS25345	COG4656	Part of a membrane complex involved in electron transport
CU111_RS25350	COG1454	alcohol dehydrogenase
CU111_RS25350	COG1012	belongs to the aldehyde dehydrogenase family
CU111_RS25380	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CU111_RS25580	COG2885	chlorophyll binding
CU111_RS25615	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CU111_RS25620	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CU111_RS25625	COG2166	iron-sulfur cluster assembly
CU111_RS25630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CU111_RS25640	COG0583	DNA-binding transcription factor activity
CU111_RS25645	COG2363	Small membrane protein
CU111_RS25655	COG1349	DNA-binding transcription factor activity
CU111_RS25675	COG0738	Major facilitator superfamily
CU111_RS25680	COG0235	Class ii aldolase
CU111_RS25685	COG1454	alcohol dehydrogenase
CU111_RS25700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CU111_RS25715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CU111_RS25720	COG2011	ABC-type metal ion transport system permease component
CU111_RS25725	COG1464	Belongs to the NlpA lipoprotein family
CU111_RS25735	COG0477	Major facilitator Superfamily
CU111_RS25745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CU111_RS25750	COG1760	l-serine dehydratase
CU111_RS25755	COG0814	amino acid
CU111_RS25760	COG1611	Belongs to the LOG family
CU111_RS25775	COG3098	single-species biofilm formation
CU111_RS25780	COG0564	pseudouridine synthase activity
CU111_RS25785	COG0716	FMN binding
CU111_RS25790	COG2271	Major facilitator Superfamily
CU111_RS25795	COG4948	Mandelate Racemase Muconate Lactonizing
CU111_RS25800	COG4948	Mandelate Racemase Muconate Lactonizing
CU111_RS25805	COG1929	Belongs to the glycerate kinase type-1 family
CU111_RS25810	COG3850	Histidine kinase
CU111_RS25810	COG3437	response regulator, receiver
CU111_RS25810	COG4999	Histidine kinase
CU111_RS25810	COG2205	protein histidine kinase activity
CU111_RS25820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CU111_RS25825	COG3956	TIGRFAM MazG family protein
CU111_RS25845	COG0602	queuosine metabolic process
CU111_RS25850	COG0720	synthase
CU111_RS25870	COG2234	aminopeptidase activity
CU111_RS25930	COG4942	peptidase
CU111_RS25930	COG1388	LysM domain
CU111_RS25935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CU111_RS25960	COG0163	prenyltransferase activity
CU111_RS25965	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CU111_RS26015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU111_RS26020	COG4558	Periplasmic binding protein
CU111_RS26025	COG3720	iron ion transport
CU111_RS26045	COG0679	Auxin Efflux Carrier
CU111_RS26060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CU111_RS26065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CU111_RS26070	COG1121	(ABC) transporter
CU111_RS26075	COG0803	Belongs to the bacterial solute-binding protein 9 family
CU111_RS26080	COG1609	Transcriptional regulator
CU111_RS26085	COG1940	carbohydrate kinase activity
CU111_RS26090	COG1447	Phosphotransferase system cellobiose-specific component IIA
CU111_RS26095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU111_RS26100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU111_RS26105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU111_RS26115	COG4580	involved in the transport of maltose and maltodextrins
CU111_RS26125	COG2723	6-phospho-beta-galactosidase activity
CU111_RS26135	COG0309	Hydrogenase expression formation protein (HypE)
CU111_RS26140	COG0409	Hydrogenase expression formation protein
CU111_RS26145	COG0298	carbon dioxide binding
CU111_RS26150	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CU111_RS26170	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CU111_RS26175	COG0651	ATP synthesis coupled electron transport
CU111_RS26180	COG0650	Formate hydrogenlyase subunit 4
CU111_RS26185	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CU111_RS26185	COG3261	NADH dehydrogenase
CU111_RS26190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CU111_RS26195	COG3260	NADH ubiquinone oxidoreductase 20
CU111_RS26205	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CU111_RS26215	COG2723	6-phospho-beta-galactosidase activity
CU111_RS26220	COG1263	PTS System
CU111_RS26220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU111_RS26225	COG1609	Transcriptional regulator
CU111_RS26230	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CU111_RS26235	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CU111_RS26240	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CU111_RS26270	COG1349	DNA-binding transcription factor activity
CU111_RS26275	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU111_RS26280	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS26290	COG3732	PTS system glucitol sorbitol-specific
CU111_RS26295	COG3730	PTS system glucitol sorbitol-specific
CU111_RS26300	COG2951	lytic endotransglycosylase activity
CU111_RS26310	COG1121	(ABC) transporter
CU111_RS26315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CU111_RS26325	COG1546	Belongs to the CinA family
CU111_RS26350	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CU111_RS26380	COG2823	Periplasmic or secreted lipoprotein
CU111_RS26385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CU111_RS26390	COG1238	metal cluster binding
CU111_RS26410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CU111_RS26415	COG2814	Major facilitator Superfamily
CU111_RS26420	COG1566	PFAM secretion protein HlyD family protein
CU111_RS26425	COG1846	Transcriptional regulator
CU111_RS26435	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CU111_RS26445	COG4176	ABC-type proline glycine betaine transport system permease component
CU111_RS26460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CU111_RS26470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CU111_RS26475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CU111_RS26480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CU111_RS26485	COG4575	ribosome binding
CU111_RS26510	COG2916	Histone family protein nucleoid-structuring protein H-NS
CU111_RS26525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CU111_RS26530	COG0640	Transcriptional regulator
CU111_RS26540	COG0583	DNA-binding transcription factor activity
CU111_RS26545	COG3284	Transcriptional regulator
CU111_RS26555	COG3539	Fimbrial protein
CU111_RS26560	COG3121	Chaperone
CU111_RS26580	COG3188	usher protein
CU111_RS26590	COG3539	Fimbrial protein
CU111_RS26595	COG2197	response regulator
CU111_RS26610	COG1028	Short-chain dehydrogenase reductase Sdr
CU111_RS26620	COG0235	Class ii aldolase
CU111_RS26630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU111_RS26665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU111_RS26670	COG3708	Transcriptional regulator
CU111_RS26670	COG2207	Transcriptional regulator
CU111_RS26700	COG2867	negative regulation of translational initiation
CU111_RS26715	COG0497	DNA recombination
CU111_RS26735	COG4536	flavin adenine dinucleotide binding
CU111_RS26740	COG4137	Cytochrome C assembly protein
CU111_RS26745	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CU111_RS26780	COG2885	chlorophyll binding
CU111_RS26785	COG2199	diguanylate cyclase activity
CU111_RS26795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CU111_RS26800	COG0287	Prephenate dehydrogenase
CU111_RS26800	COG1605	Chorismate mutase
CU111_RS26810	COG0077	Prephenate dehydratase
CU111_RS26810	COG1605	Chorismate mutase
CU111_RS26820	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CU111_RS26825	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CU111_RS26840	COG0071	Belongs to the small heat shock protein (HSP20) family
CU111_RS26845	COG0542	response to heat
CU111_RS26870	COG0501	Belongs to the peptidase M48B family
CU111_RS26890	COG3436	PFAM IS66 Orf2 family protein
CU111_RS26920	COG5642	Protein of unknown function (DUF2384)
CU111_RS26925	COG5654	RES domain protein
CU111_RS26960	COG0583	DNA-binding transcription factor activity
CU111_RS26970	COG0765	amino acid transport
CU111_RS26975	COG0765	amino acid transport
CU111_RS26980	COG4598	ABC transporter
CU111_RS26990	COG3039	Transposase
CU111_RS27000	COG4372	Transposase
CU111_RS27005	COG3436	PFAM IS66 Orf2 family protein
CU111_RS27020	COG4680	protein conserved in bacteria
CU111_RS27025	COG5499	transcription regulator containing HTH domain
CU111_RS27050	COG0402	S-adenosylhomocysteine deaminase activity
CU111_RS27055	COG2188	Transcriptional regulator
CU111_RS27065	COG2986	histidine ammonia-lyase
CU111_RS27095	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CU111_RS27175	COG2801	Transposase and inactivated derivatives
CU111_RS27185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CU111_RS27240	COG2801	Transposase and inactivated derivatives
CU111_RS27415	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
CU111_RS27425	COG1609	Transcriptional regulator
CU111_RS27435	COG2223	nitrite transmembrane transporter activity
CU111_RS27440	COG0110	maltose O-acetyltransferase activity
CU111_RS27475	COG0418	dihydroorotase activity
CU111_RS27490	COG0543	2 iron, 2 sulfur cluster binding
CU111_RS27495	COG2814	Major facilitator Superfamily
CU111_RS27505	COG3039	Transposase
CU111_RS27515	COG2372	response to copper ion
CU111_RS27585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CU111_RS27600	COG0431	NADPH-dependent FMN reductase
CU111_RS27605	COG1393	Belongs to the ArsC family
CU111_RS27610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CU111_RS27620	COG0659	secondary active sulfate transmembrane transporter activity
CU111_RS27625	COG0589	response to stress
CU111_RS27635	COG0789	Transcriptional regulator
CU111_RS27775	COG3436	PFAM IS66 Orf2 family protein
CU111_RS27780	COG4372	Transposase
CU111_RS27795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CU111_RS27805	COG0577	efflux transmembrane transporter activity
CU111_RS27805	COG1136	(ABC) transporter
CU111_RS27905	COG3344	reverse transcriptase
CU111_RS27970	COG3547	Transposase (IS116 IS110 IS902 family)
CU111_RS28020	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU111_RS28050	COG0739	heme binding
CU111_RS28065	COG3667	copper resistance
CU111_RS28070	COG2372	response to copper ion
CU111_RS28075	COG1276	copper resistance
CU111_RS28080	COG0745	RESPONSE REGULATOR receiver
CU111_RS28120	COG3436	PFAM IS66 Orf2 family protein
CU111_RS28235	COG0697	spore germination
CU111_RS28275	COG3039	Transposase
CU111_RS28285	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CU111_RS28495	COG3328	transposase activity
CU111_RS28500	COG5499	transcription regulator containing HTH domain
CU111_RS28585	COG1475	DNA binding
CU111_RS28690	COG4372	Transposase
CU111_RS28695	COG3436	PFAM IS66 Orf2 family protein
CU111_RS28720	COG3344	reverse transcriptase
CU111_RS28745	COG1192	Involved in chromosome partitioning
CU111_RS28870	COG2135	peptidase activity
CU111_RS28895	COG4644	lycopene metabolic process
CU111_RS29020	COG3173	Aminoglycoside phosphotransferase
CU111_RS29055	COG1695	Transcriptional regulator
CU111_RS29105	COG3941	tape measure
CU111_RS29195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CU111_RS29200	COG1475	DNA binding
CU111_RS29205	COG1475	DNA binding
CU111_RS29335	COG0328	RNA-DNA hybrid ribonuclease activity
CU111_RS29355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CU111_RS29380	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CU111_RS29390	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CU111_RS29395	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CU111_RS29470	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CU111_RS29480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CU111_RS29555	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CU111_RS29565	COG1702	phosphate starvation-inducible protein PhoH
CU111_RS29650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CU111_RS29875	COG1349	DNA-binding transcription factor activity
CU111_RS29945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CU111_RS29975	COG2003	Belongs to the UPF0758 family
CU111_RS30040	COG0629	single-stranded DNA binding
CU111_RS30215	COG3451	type IV secretory pathway VirB4
CU111_RS30260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CU111_RS30310	COG1482	cell wall glycoprotein biosynthetic process
CU111_RS30320	COG4644	lycopene metabolic process