locus-tag	class	description
HV292_RS00020	COG0187	DNA topoisomerase II activity
HV292_RS00025	COG0561	phosphatase activity
HV292_RS00040	COG2186	Transcriptional regulator
HV292_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
HV292_RS00050	COG0800	Aldolase
HV292_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
HV292_RS00070	COG5645	(Lipo)protein
HV292_RS00085	COG3645	SOS response
HV292_RS00095	COG2188	Transcriptional regulator
HV292_RS00110	COG2149	membrane
HV292_RS00130	COG2610	gluconate transmembrane transporter activity
HV292_RS00140	COG0583	DNA-binding transcription factor activity
HV292_RS00145	COG2814	Major facilitator Superfamily
HV292_RS00175	COG0028	Belongs to the TPP enzyme family
HV292_RS00180	COG0440	acetolactate synthase activity
HV292_RS00185	COG2197	response regulator
HV292_RS00195	COG2271	Major facilitator Superfamily
HV292_RS00235	COG2188	Transcriptional regulator
HV292_RS00260	COG4580	involved in the transport of maltose and maltodextrins
HV292_RS00265	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV292_RS00270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV292_RS00270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV292_RS00280	COG1609	Transcriptional regulator
HV292_RS00290	COG3384	dioxygenase
HV292_RS00295	COG0583	DNA-binding transcription factor activity
HV292_RS00300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HV292_RS00305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HV292_RS00310	COG2828	Protein conserved in bacteria
HV292_RS00325	COG0697	spore germination
HV292_RS00330	COG1263	PTS System
HV292_RS00330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV292_RS00340	COG2814	Major facilitator Superfamily
HV292_RS00350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV292_RS00385	COG0583	DNA-binding transcription factor activity
HV292_RS00410	COG1464	Belongs to the NlpA lipoprotein family
HV292_RS00425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HV292_RS00435	COG1064	alcohol dehydrogenase
HV292_RS00465	COG2211	Major facilitator Superfamily
HV292_RS00470	COG1501	Belongs to the glycosyl hydrolase 31 family
HV292_RS00480	COG1486	melibiose metabolic process
HV292_RS00485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV292_RS00485	COG1263	PTS System
HV292_RS00490	COG2982	Protein involved in outer membrane biogenesis
HV292_RS00495	COG2233	PERMEase
HV292_RS00500	COG0786	glutamate:sodium symporter activity
HV292_RS00520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HV292_RS00545	COG3152	Membrane
HV292_RS00555	COG1494	fructose-1,6-bisphosphatase
HV292_RS00560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HV292_RS00565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV292_RS00570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV292_RS00590	COG2860	membrane
HV292_RS00600	COG2169	Transcriptional regulator
HV292_RS00600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HV292_RS00605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HV292_RS00610	COG1561	YicC-like family, N-terminal region
HV292_RS00615	COG3039	Transposase
HV292_RS00650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HV292_RS00685	COG1519	Transferase
HV292_RS00690	COG1216	Glycosyl transferase, family 2
HV292_RS00695	COG0438	transferase activity, transferring glycosyl groups
HV292_RS00705	COG0859	PFAM glycosyl transferase family 9
HV292_RS00730	COG0859	PFAM glycosyl transferase family 9
HV292_RS00745	COG0156	8-amino-7-oxononanoate synthase activity
HV292_RS00755	COG0463	Glycosyl transferase, family 2
HV292_RS00760	COG2861	carbohydrate metabolic process
HV292_RS00765	COG4942	peptidase
HV292_RS00775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV292_RS00780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV292_RS00800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HV292_RS00810	COG2186	Transcriptional regulator
HV292_RS00830	COG3722	fumarate hydratase activity
HV292_RS00850	COG1566	PFAM secretion protein HlyD family protein
HV292_RS00855	COG0625	glutathione transferase activity
HV292_RS00865	COG3276	selenocysteine insertion sequence binding
HV292_RS00870	COG1414	Transcriptional regulator
HV292_RS00875	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV292_RS00880	COG3977	Valine--pyruvate aminotransferase
HV292_RS00885	COG0366	Alpha amylase catalytic
HV292_RS00890	COG2992	FlgJ-related protein
HV292_RS00895	COG2207	Transcriptional regulator
HV292_RS00895	COG1609	Transcriptional regulator
HV292_RS00900	COG4214	carbohydrate transport
HV292_RS00910	COG4213	ABC transporter substrate-binding protein
HV292_RS00925	COG4682	membrane
HV292_RS00930	COG4682	membrane
HV292_RS00935	COG3274	enterobacterial common antigen metabolic process
HV292_RS00965	COG1278	Cold shock
HV292_RS00970	COG2944	sequence-specific DNA binding
HV292_RS00975	COG2814	Major facilitator Superfamily
HV292_RS00995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV292_RS01005	COG1609	Transcriptional regulator
HV292_RS01010	COG2885	chlorophyll binding
HV292_RS01015	COG0243	molybdopterin cofactor binding
HV292_RS01020	COG0456	acetyltransferase
HV292_RS01025	COG2818	Glycosylase
HV292_RS01030	COG5571	outer membrane autotransporter
HV292_RS01035	COG2223	nitrite transmembrane transporter activity
HV292_RS01060	COG0747	negative chemotaxis
HV292_RS01065	COG0601	transmembrane transport
HV292_RS01070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV292_RS01075	COG0444	Belongs to the ABC transporter superfamily
HV292_RS01080	COG4608	Belongs to the ABC transporter superfamily
HV292_RS01095	COG2894	cell division
HV292_RS01105	COG1215	transferase activity, transferring glycosyl groups
HV292_RS01125	COG2194	sulfuric ester hydrolase activity
HV292_RS01155	COG1215	transferase activity, transferring glycosyl groups
HV292_RS01160	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HV292_RS01165	COG3118	belongs to the thioredoxin family
HV292_RS01165	COG0457	Tetratricopeptide repeat
HV292_RS01170	COG2200	EAL domain
HV292_RS01170	COG2199	diguanylate cyclase activity
HV292_RS01180	COG0612	Peptidase, M16
HV292_RS01190	COG2982	Protein involved in outer membrane biogenesis
HV292_RS01195	COG0477	Major facilitator Superfamily
HV292_RS01200	COG1295	ribonuclease BN
HV292_RS01205	COG0583	DNA-binding transcription factor activity
HV292_RS01210	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS01215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV292_RS01225	COG1454	alcohol dehydrogenase
HV292_RS01235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV292_RS01240	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HV292_RS01245	COG0671	phosphoesterase, PA-phosphatase related
HV292_RS01265	COG0589	response to stress
HV292_RS01275	COG0306	phosphate transporter
HV292_RS01280	COG2081	HI0933 family
HV292_RS01285	COG2239	Acts as a magnesium transporter
HV292_RS01295	COG1124	(ABC) transporter
HV292_RS01305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV292_RS01310	COG0601	transmembrane transport
HV292_RS01315	COG0747	negative chemotaxis
HV292_RS01325	COG3479	Phenolic acid decarboxylase
HV292_RS01345	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV292_RS01460	COG4373	Mu-like prophage FluMu protein gp28
HV292_RS01470	COG0640	Transcriptional regulator
HV292_RS01485	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HV292_RS01535	COG3267	Type II secretory pathway component ExeA
HV292_RS01535	COG3409	Peptidoglycan-binding domain 1 protein
HV292_RS01610	COG0628	permease
HV292_RS01615	COG0477	Major facilitator Superfamily
HV292_RS01625	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HV292_RS01640	COG3714	YhhN family
HV292_RS01650	COG3776	membrane
HV292_RS01655	COG0742	ribosomal rna small subunit methyltransferase
HV292_RS01660	COG0552	protein localization to endoplasmic reticulum
HV292_RS01665	COG2884	Cell division ATP-binding protein ftsE
HV292_RS01670	COG2177	Part of the ABC transporter FtsEX involved in
HV292_RS01685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV292_RS01700	COG0683	leucine binding
HV292_RS01710	COG0683	leucine binding
HV292_RS01715	COG0559	Belongs to the binding-protein-dependent transport system permease family
HV292_RS01765	COG0584	glycerophosphoryl diester phosphodiesterase
HV292_RS01775	COG0405	Gamma-glutamyltransferase
HV292_RS01780	COG1247	-acetyltransferase
HV292_RS01790	COG0673	inositol 2-dehydrogenase activity
HV292_RS01795	COG1741	Belongs to the pirin family
HV292_RS01800	COG1609	Transcriptional regulator
HV292_RS01805	COG3265	gluconokinase activity
HV292_RS01810	COG2610	gluconate transmembrane transporter activity
HV292_RS01820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV292_RS01845	COG0058	SHG alpha-glucan phosphorylase activity
HV292_RS01860	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV292_RS01875	COG1349	DNA-binding transcription factor activity
HV292_RS01885	COG0058	SHG alpha-glucan phosphorylase activity
HV292_RS01890	COG1640	4-alpha-glucanotransferase
HV292_RS01895	COG2610	gluconate transmembrane transporter activity
HV292_RS01905	COG1040	competence protein
HV292_RS01930	COG1918	ferrous iron import across plasma membrane
HV292_RS01935	COG2183	response to ionizing radiation
HV292_RS01940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV292_RS01945	COG0745	RESPONSE REGULATOR receiver
HV292_RS01965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HV292_RS01970	COG1011	Hydrolase
HV292_RS01980	COG0494	nUDIX hydrolase
HV292_RS01985	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HV292_RS02010	COG4796	Type ii and iii secretion system protein
HV292_RS02025	COG3266	domain, Protein
HV292_RS02030	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV292_RS02035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV292_RS02060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV292_RS02065	COG0402	S-adenosylhomocysteine deaminase activity
HV292_RS02070	COG0738	Major facilitator superfamily
HV292_RS02095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HV292_RS02100	COG1289	transmembrane transporter activity
HV292_RS02110	COG1765	OsmC-like protein
HV292_RS02115	COG3954	Phosphoribulokinase
HV292_RS02125	COG0429	hydrolase of the alpha beta-hydrolase fold
HV292_RS02130	COG0488	(ABC) transporter
HV292_RS02145	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HV292_RS02150	COG1047	Peptidyl-prolyl cis-trans
HV292_RS02160	COG0545	Peptidyl-prolyl cis-trans isomerase
HV292_RS02165	COG2964	Protein conserved in bacteria
HV292_RS02220	COG0051	transcription antitermination factor activity, RNA binding
HV292_RS02245	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HV292_RS02260	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HV292_RS02325	COG0201	protein transport
HV292_RS02350	COG0202	RNA polymerase activity
HV292_RS02365	COG0789	Transcriptional regulator
HV292_RS02370	COG3036	rescue of stalled ribosome
HV292_RS02400	COG0758	DNA mediated transformation
HV292_RS02410	COG0551	DNA topoisomerase type I activity
HV292_RS02430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV292_RS02465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV292_RS02470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV292_RS02475	COG1309	transcriptional regulator
HV292_RS02495	COG4145	pantothenate transmembrane transporter activity
HV292_RS02500	COG3924	membrane
HV292_RS02505	COG0439	Biotin carboxylase
HV292_RS02510	COG0511	ligase activity, forming carbon-carbon bonds
HV292_RS02535	COG2199	diguanylate cyclase activity
HV292_RS02535	COG2200	EAL domain
HV292_RS02540	COG1077	Cell shape determining protein MreB Mrl
HV292_RS02545	COG1792	Involved in formation and maintenance of cell shape
HV292_RS02550	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HV292_RS02560	COG1530	ribonuclease E activity
HV292_RS02565	COG3164	Protein of unknown function
HV292_RS02570	COG0312	modulator of DNA gyrase
HV292_RS02575	COG0583	DNA-binding transcription factor activity
HV292_RS02590	COG1289	transmembrane transporter activity
HV292_RS02595	COG2732	(Barnase) inhibitor
HV292_RS02630	COG0471	metal ion transport
HV292_RS02635	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV292_RS02640	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV292_RS02665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV292_RS02670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV292_RS02675	COG3105	Protein conserved in bacteria
HV292_RS02680	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HV292_RS02695	COG0625	glutathione transferase activity
HV292_RS02700	COG2969	positive regulation of protein catabolic process
HV292_RS02710	COG0493	'glutamate synthase
HV292_RS02715	COG0067	glutamate synthase
HV292_RS02715	COG0070	glutamate synthase
HV292_RS02715	COG0069	glutamate synthase activity
HV292_RS02720	COG1242	4 iron, 4 sulfur cluster binding
HV292_RS02725	COG2271	Major facilitator Superfamily
HV292_RS02730	COG1063	alcohol dehydrogenase
HV292_RS02735	COG1312	Catalyzes the dehydration of D-mannonate
HV292_RS02740	COG2198	Histidine kinase
HV292_RS02740	COG5002	protein histidine kinase activity
HV292_RS02740	COG0784	Response regulator, receiver
HV292_RS02745	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HV292_RS02750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HV292_RS02755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV292_RS02765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV292_RS02770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV292_RS02775	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HV292_RS02780	COG1137	ATPase activity
HV292_RS02785	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HV292_RS02790	COG3117	lipopolysaccharide transmembrane transporter activity
HV292_RS02795	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HV292_RS02805	COG0530	calcium, potassium:sodium antiporter activity
HV292_RS02810	COG1127	ABC transporter
HV292_RS02815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV292_RS02820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV292_RS02825	COG2854	intermembrane phospholipid transfer
HV292_RS02830	COG3113	response to antibiotic
HV292_RS02835	COG5007	Belongs to the BolA IbaG family
HV292_RS02845	COG3423	Transcriptional regulator
HV292_RS02850	COG0142	geranyltranstransferase activity
HV292_RS02865	COG0697	spore germination
HV292_RS02875	COG2027	D-alanyl-D-alanine carboxypeptidase
HV292_RS02885	COG1534	Rna-binding protein
HV292_RS02895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HV292_RS02900	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HV292_RS02910	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HV292_RS02950	COG0195	Participates in both transcription termination and antitermination
HV292_RS02995	COG0814	amino acid
HV292_RS03000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV292_RS03005	COG0826	peptidase U32
HV292_RS03010	COG0826	peptidase U32
HV292_RS03015	COG3154	lipid carrier protein
HV292_RS03020	COG3153	acetyltransferase
HV292_RS03035	COG0693	protein deglycase activity
HV292_RS03040	COG0702	epimerase
HV292_RS03045	COG0701	Predicted permease
HV292_RS03050	COG2823	Periplasmic or secreted lipoprotein
HV292_RS03070	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HV292_RS03075	COG2721	sulfolactate sulfo-lyase activity
HV292_RS03080	COG2271	Major facilitator Superfamily
HV292_RS03090	COG2084	Dehydrogenase
HV292_RS03095	COG1929	Belongs to the glycerate kinase type-1 family
HV292_RS03120	COG1741	Belongs to the pirin family
HV292_RS03125	COG0583	DNA-binding transcription factor activity
HV292_RS03130	COG3152	Membrane
HV292_RS03135	COG0435	Glutathione S-transferase
HV292_RS03140	COG2259	Doxx family
HV292_RS03150	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HV292_RS03155	COG4575	ribosome binding
HV292_RS03160	COG1422	Protein of unknown function (DUF1090)
HV292_RS03170	COG0586	Pfam SNARE associated Golgi protein
HV292_RS03175	COG2186	Transcriptional regulator
HV292_RS03180	COG2271	Major facilitator Superfamily
HV292_RS03190	COG2721	sulfolactate sulfo-lyase activity
HV292_RS03205	COG0861	Integral membrane protein TerC family
HV292_RS03210	COG0673	inositol 2-dehydrogenase activity
HV292_RS03215	COG1451	nucleotide metabolic process
HV292_RS03235	COG0446	pyridine nucleotide-disulphide oxidoreductase
HV292_RS03235	COG1902	pentaerythritol trinitrate reductase activity
HV292_RS03285	COG1695	Transcriptional regulator
HV292_RS03290	COG2375	cellular response to nickel ion
HV292_RS03305	COG1461	Dihydroxyacetone kinase
HV292_RS03310	COG2376	Dihydroxyacetone kinase
HV292_RS03380	COG3247	response to pH
HV292_RS03390	COG2198	Histidine kinase
HV292_RS03390	COG2205	protein histidine kinase activity
HV292_RS03390	COG0784	Response regulator, receiver
HV292_RS03390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV292_RS03395	COG2197	response regulator
HV292_RS03415	COG3550	peptidyl-serine autophosphorylation
HV292_RS03440	COG2003	Belongs to the UPF0758 family
HV292_RS03455	COG4974	Belongs to the 'phage' integrase family
HV292_RS03495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV292_RS03515	COG3344	reverse transcriptase
HV292_RS03540	COG4695	Portal protein
HV292_RS03620	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HV292_RS03690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HV292_RS03695	COG0358	DNA primase activity
HV292_RS03700	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HV292_RS03765	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV292_RS03780	COG4991	sh3 domain protein
HV292_RS03785	COG3025	triphosphatase activity
HV292_RS03810	COG2960	long-chain fatty acid transporting porin activity
HV292_RS03825	COG3384	dioxygenase
HV292_RS03830	COG0754	glutathionylspermidine amidase activity
HV292_RS03845	COG0494	nUDIX hydrolase
HV292_RS03850	COG3151	Protein conserved in bacteria
HV292_RS03855	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HV292_RS03860	COG3150	esterase
HV292_RS03870	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HV292_RS03875	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV292_RS03880	COG0642	Histidine kinase
HV292_RS03890	COG3111	PFAM Bacterial OB fold (BOF) protein
HV292_RS03900	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HV292_RS03905	COG0204	Acyl-transferase
HV292_RS03910	COG2132	Multicopper oxidase
HV292_RS03915	COG1032	radical SAM domain protein
HV292_RS03925	COG0656	L-ascorbic acid biosynthetic process
HV292_RS03930	COG1979	alcohol dehydrogenase
HV292_RS03935	COG2207	Transcriptional regulator
HV292_RS03940	COG0586	Pfam SNARE associated Golgi protein
HV292_RS03945	COG0626	cystathionine gamma-synthase activity
HV292_RS03960	COG0848	biopolymer transport protein
HV292_RS03965	COG2211	Major facilitator Superfamily
HV292_RS03990	COG0625	glutathione transferase activity
HV292_RS04005	COG0754	glutathionylspermidine amidase activity
HV292_RS04010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV292_RS04030	COG0583	DNA-binding transcription factor activity
HV292_RS04035	COG0626	cystathionine gamma-synthase activity
HV292_RS04055	COG3039	Transposase
HV292_RS04075	COG1811	Na channel or pump
HV292_RS04080	COG1982	Orn Lys Arg decarboxylase major
HV292_RS04085	COG2211	Major facilitator Superfamily
HV292_RS04100	COG1194	a g-specific adenine glycosylase
HV292_RS04110	COG3171	Protein conserved in bacteria
HV292_RS04120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV292_RS04135	COG0762	integral membrane protein
HV292_RS04140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HV292_RS04145	COG2805	Type II/IV secretion system protein
HV292_RS04150	COG3039	Transposase
HV292_RS04170	COG0189	ligase activity
HV292_RS04175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HV292_RS04180	COG2356	endonuclease I
HV292_RS04225	COG2146	nitrite reductase [NAD(P)H] activity
HV292_RS04240	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS04245	COG1414	Transcriptional regulator
HV292_RS04275	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS04280	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HV292_RS04300	COG0501	Belongs to the peptidase M48B family
HV292_RS04305	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV292_RS04320	COG0191	fructose-bisphosphate aldolase activity
HV292_RS04325	COG0668	transmembrane transport
HV292_RS04335	COG2968	Membrane
HV292_RS04350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV292_RS04355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HV292_RS04375	COG0006	proline dipeptidase activity
HV292_RS04380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV292_RS04385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV292_RS04405	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS04410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HV292_RS04430	COG2723	6-phospho-beta-galactosidase activity
HV292_RS04435	COG1737	Transcriptional regulator
HV292_RS04445	COG1272	protein, Hemolysin III
HV292_RS04455	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HV292_RS04465	COG0716	FMN binding
HV292_RS04470	COG4974	Belongs to the 'phage' integrase family
HV292_RS04480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HV292_RS04500	COG4942	peptidase
HV292_RS04510	COG2814	Major facilitator Superfamily
HV292_RS04525	COG0667	Aldo Keto reductase
HV292_RS04565	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV292_RS04570	COG1393	Belongs to the ArsC family
HV292_RS04580	COG3039	Transposase
HV292_RS04620	COG0667	Aldo Keto reductase
HV292_RS04625	COG0814	amino acid
HV292_RS04640	COG0183	Belongs to the thiolase family
HV292_RS04650	COG0823	Involved in the tonB-independent uptake of proteins
HV292_RS04655	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS04660	COG2814	Major facilitator Superfamily
HV292_RS04695	COG3842	ATPase activity
HV292_RS04700	COG0395	ABC-type sugar transport system, permease component
HV292_RS04705	COG1175	transmembrane transport
HV292_RS04710	COG1917	Cupin 2, conserved barrel domain protein
HV292_RS04715	COG1794	racemase activity, acting on amino acids and derivatives
HV292_RS04720	COG0583	DNA-binding transcription factor activity
HV292_RS04730	COG1609	Transcriptional regulator
HV292_RS04735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV292_RS04740	COG2723	6-phospho-beta-galactosidase activity
HV292_RS04745	COG2186	Transcriptional regulator
HV292_RS04755	COG1609	Transcriptional regulator
HV292_RS04770	COG0667	Aldo Keto reductase
HV292_RS04780	COG0861	Integral membrane protein TerC family
HV292_RS04815	COG2165	general secretion pathway protein
HV292_RS04820	COG4795	General secretion pathway protein
HV292_RS04830	COG4967	type IV pilus modification protein PilV
HV292_RS04835	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HV292_RS04840	COG1025	Belongs to the peptidase M16 family
HV292_RS04845	COG1074	ATP-dependent DNA helicase activity
HV292_RS04850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HV292_RS04860	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HV292_RS04860	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HV292_RS04865	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV292_RS04870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HV292_RS04900	COG4656	Part of a membrane complex involved in electron transport
HV292_RS04905	COG1454	alcohol dehydrogenase
HV292_RS04905	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS05100	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HV292_RS05105	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HV292_RS05110	COG2166	iron-sulfur cluster assembly
HV292_RS05115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HV292_RS05125	COG0583	DNA-binding transcription factor activity
HV292_RS05130	COG2363	Small membrane protein
HV292_RS05140	COG1349	DNA-binding transcription factor activity
HV292_RS05160	COG0738	Major facilitator superfamily
HV292_RS05165	COG0235	Class ii aldolase
HV292_RS05170	COG1454	alcohol dehydrogenase
HV292_RS05190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV292_RS05205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HV292_RS05210	COG2011	ABC-type metal ion transport system permease component
HV292_RS05215	COG1464	Belongs to the NlpA lipoprotein family
HV292_RS05220	COG0477	Major facilitator Superfamily
HV292_RS05230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV292_RS05235	COG1760	l-serine dehydratase
HV292_RS05240	COG0814	amino acid
HV292_RS05245	COG1611	Belongs to the LOG family
HV292_RS05260	COG3098	single-species biofilm formation
HV292_RS05265	COG0564	pseudouridine synthase activity
HV292_RS05270	COG0716	FMN binding
HV292_RS05275	COG2271	Major facilitator Superfamily
HV292_RS05280	COG4948	Mandelate Racemase Muconate Lactonizing
HV292_RS05285	COG4948	Mandelate Racemase Muconate Lactonizing
HV292_RS05290	COG1929	Belongs to the glycerate kinase type-1 family
HV292_RS05295	COG2205	protein histidine kinase activity
HV292_RS05295	COG3850	Histidine kinase
HV292_RS05295	COG4999	Histidine kinase
HV292_RS05295	COG3437	response regulator, receiver
HV292_RS05305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV292_RS05310	COG3956	TIGRFAM MazG family protein
HV292_RS05330	COG0602	queuosine metabolic process
HV292_RS05335	COG0720	synthase
HV292_RS05355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV292_RS05465	COG4373	Mu-like prophage FluMu protein gp28
HV292_RS05490	COG0741	lytic transglycosylase activity
HV292_RS05535	COG3267	Type II secretory pathway component ExeA
HV292_RS05535	COG3409	Peptidoglycan-binding domain 1 protein
HV292_RS05625	COG1857	crispr-associated protein
HV292_RS05640	COG1518	maintenance of DNA repeat elements
HV292_RS05645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV292_RS05660	COG2234	aminopeptidase activity
HV292_RS05720	COG1388	LysM domain
HV292_RS05720	COG4942	peptidase
HV292_RS05725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HV292_RS05750	COG0163	prenyltransferase activity
HV292_RS05755	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV292_RS05795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV292_RS05800	COG4558	Periplasmic binding protein
HV292_RS05805	COG3720	iron ion transport
HV292_RS05825	COG0679	Auxin Efflux Carrier
HV292_RS05840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV292_RS05845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV292_RS05850	COG1121	(ABC) transporter
HV292_RS05860	COG1609	Transcriptional regulator
HV292_RS05865	COG1940	carbohydrate kinase activity
HV292_RS05870	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV292_RS05875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV292_RS05880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV292_RS05885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV292_RS05890	COG4580	involved in the transport of maltose and maltodextrins
HV292_RS05900	COG2723	6-phospho-beta-galactosidase activity
HV292_RS05910	COG0309	Hydrogenase expression formation protein (HypE)
HV292_RS05915	COG0409	Hydrogenase expression formation protein
HV292_RS05920	COG0298	carbon dioxide binding
HV292_RS05925	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HV292_RS05940	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV292_RS05945	COG0651	ATP synthesis coupled electron transport
HV292_RS05950	COG0650	Formate hydrogenlyase subunit 4
HV292_RS05955	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HV292_RS05955	COG3261	NADH dehydrogenase
HV292_RS05960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV292_RS05965	COG3260	NADH ubiquinone oxidoreductase 20
HV292_RS05975	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HV292_RS05985	COG2723	6-phospho-beta-galactosidase activity
HV292_RS05990	COG1263	PTS System
HV292_RS05990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV292_RS05995	COG1609	Transcriptional regulator
HV292_RS06000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV292_RS06005	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HV292_RS06010	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HV292_RS06035	COG1349	DNA-binding transcription factor activity
HV292_RS06040	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV292_RS06045	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS06055	COG3732	PTS system glucitol sorbitol-specific
HV292_RS06060	COG3730	PTS system glucitol sorbitol-specific
HV292_RS06065	COG2951	lytic endotransglycosylase activity
HV292_RS06070	COG1121	(ABC) transporter
HV292_RS06075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV292_RS06080	COG0803	Belongs to the bacterial solute-binding protein 9 family
HV292_RS06085	COG1546	Belongs to the CinA family
HV292_RS06105	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HV292_RS06135	COG2823	Periplasmic or secreted lipoprotein
HV292_RS06140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV292_RS06145	COG1238	metal cluster binding
HV292_RS06165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HV292_RS06170	COG2814	Major facilitator Superfamily
HV292_RS06175	COG1566	PFAM secretion protein HlyD family protein
HV292_RS06180	COG1846	Transcriptional regulator
HV292_RS06190	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV292_RS06200	COG4176	ABC-type proline glycine betaine transport system permease component
HV292_RS06215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV292_RS06225	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV292_RS06230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV292_RS06235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV292_RS06240	COG4575	ribosome binding
HV292_RS06255	COG3039	Transposase
HV292_RS06265	COG2916	Histone family protein nucleoid-structuring protein H-NS
HV292_RS06280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV292_RS06285	COG0640	Transcriptional regulator
HV292_RS06295	COG0583	DNA-binding transcription factor activity
HV292_RS06300	COG3284	Transcriptional regulator
HV292_RS06305	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS06400	COG0582	viral genome integration into host DNA
HV292_RS06415	COG2867	negative regulation of translational initiation
HV292_RS06430	COG0497	DNA recombination
HV292_RS06445	COG4536	flavin adenine dinucleotide binding
HV292_RS06450	COG4137	Cytochrome C assembly protein
HV292_RS06455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HV292_RS06490	COG2885	chlorophyll binding
HV292_RS06495	COG2199	diguanylate cyclase activity
HV292_RS06505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV292_RS06510	COG1605	Chorismate mutase
HV292_RS06510	COG0287	Prephenate dehydrogenase
HV292_RS06520	COG1605	Chorismate mutase
HV292_RS06520	COG0077	Prephenate dehydratase
HV292_RS06530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV292_RS06535	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV292_RS06550	COG0542	response to heat
HV292_RS06575	COG0477	Major facilitator Superfamily
HV292_RS06580	COG5544	Lipoprotein
HV292_RS06585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV292_RS06600	COG3118	belongs to the thioredoxin family
HV292_RS06605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV292_RS06620	COG0513	Belongs to the DEAD box helicase family
HV292_RS06630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HV292_RS06645	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HV292_RS06650	COG3026	antisigma factor binding
HV292_RS06655	COG3086	response to oxidative stress
HV292_RS06665	COG0681	Belongs to the peptidase S26 family
HV292_RS06685	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HV292_RS06695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV292_RS06700	COG1737	Transcriptional regulator
HV292_RS06705	COG0560	Phosphoserine phosphatase
HV292_RS06720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HV292_RS06720	COG0047	phosphoribosylformylglycinamidine synthase activity
HV292_RS06725	COG2205	protein histidine kinase activity
HV292_RS06730	COG3170	Tfp pilus assembly protein FimV
HV292_RS06735	COG2204	response regulator
HV292_RS06740	COG0347	Belongs to the P(II) protein family
HV292_RS06745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV292_RS06745	COG1017	nitric oxide dioxygenase activity
HV292_RS06755	COG2259	Doxx family
HV292_RS06760	COG1940	carbohydrate kinase activity
HV292_RS06765	COG0457	Tetratricopeptide repeat
HV292_RS06770	COG2814	Major facilitator Superfamily
HV292_RS06770	COG0477	Major facilitator Superfamily
HV292_RS06775	COG2017	converts alpha-aldose to the beta-anomer
HV292_RS06780	COG2814	Major facilitator Superfamily
HV292_RS06785	COG3711	transcriptional antiterminator
HV292_RS06790	COG3683	transport system, periplasmic component
HV292_RS06795	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HV292_RS06825	COG0822	iron-sulfur transferase activity
HV292_RS06845	COG0633	Ferredoxin
HV292_RS06850	COG2975	iron-sulfur cluster assembly
HV292_RS06870	COG2897	thiosulfate sulfurtransferase activity
HV292_RS06875	COG2373	Large extracellular alpha-helical protein
HV292_RS06880	COG4953	penicillin-binding protein 1C
HV292_RS06915	COG2976	Protein conserved in bacteria
HV292_RS06935	COG3039	Transposase
HV292_RS06950	COG1645	bacterial-type flagellum-dependent swarming motility
HV292_RS06960	COG0516	GMP reductase activity
HV292_RS06960	COG0517	IMP dehydrogenase activity
HV292_RS06970	COG3119	arylsulfatase activity
HV292_RS06975	COG0641	radical SAM
HV292_RS06995	COG2200	EAL domain
HV292_RS07010	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HV292_RS07025	COG2723	6-phospho-beta-galactosidase activity
HV292_RS07035	COG2233	PERMEase
HV292_RS07050	COG1393	Belongs to the ArsC family
HV292_RS07055	COG4783	chaperone-mediated protein folding
HV292_RS07065	COG0628	permease
HV292_RS07070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HV292_RS07075	COG2716	regulation of RNA biosynthetic process
HV292_RS07085	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HV292_RS07095	COG2321	neutral zinc metallopeptidase
HV292_RS07100	COG1444	tRNA N-acetyltransferase activity
HV292_RS07105	COG0400	carboxylic ester hydrolase activity
HV292_RS07120	COG1393	Belongs to the ArsC family
HV292_RS07130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV292_RS07135	COG0493	'glutamate synthase
HV292_RS07135	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV292_RS07145	COG5342	invasion associated locus B
HV292_RS07150	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV292_RS07155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HV292_RS07165	COG4810	utilization protein
HV292_RS07255	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV292_RS07275	COG2837	iron assimilation
HV292_RS07285	COG4150	thiosulfate binding
HV292_RS07290	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HV292_RS07295	COG4208	sulfate ABC transporter
HV292_RS07300	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HV292_RS07310	COG4319	ketosteroid isomerase
HV292_RS07345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HV292_RS07365	COG3530	Putative quorum-sensing-regulated virulence factor
HV292_RS07370	COG0385	Bile acid
HV292_RS07375	COG0583	DNA-binding transcription factor activity
HV292_RS07405	COG3415	Transposase
HV292_RS07410	COG3415	Transposase
HV292_RS07425	COG2200	EAL domain
HV292_RS07425	COG2199	diguanylate cyclase activity
HV292_RS07430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV292_RS07445	COG0667	Aldo Keto reductase
HV292_RS07450	COG3961	Belongs to the TPP enzyme family
HV292_RS07465	COG3279	Response regulator of the LytR AlgR family
HV292_RS07470	COG3275	phosphorelay sensor kinase activity
HV292_RS07485	COG0436	Aminotransferase
HV292_RS07495	COG2807	transmembrane transport
HV292_RS07500	COG0590	tRNA wobble adenosine to inosine editing
HV292_RS07505	COG0583	DNA-binding transcription factor activity
HV292_RS07540	COG2885	chlorophyll binding
HV292_RS07760	COG0582	viral genome integration into host DNA
HV292_RS07770	COG2116	formate transmembrane transporter activity
HV292_RS07775	COG2853	Lipoprotein
HV292_RS07785	COG3691	Protein conserved in bacteria
HV292_RS07800	COG2062	phosphohistidine phosphatase, SixA
HV292_RS07825	COG0730	response to heat
HV292_RS07830	COG3101	peptidyl-lysine hydroxylation
HV292_RS07845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV292_RS07865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV292_RS07875	COG0586	Pfam SNARE associated Golgi protein
HV292_RS07885	COG0285	dihydrofolate synthase activity
HV292_RS07890	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HV292_RS07895	COG1286	toxin biosynthetic process
HV292_RS07900	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HV292_RS07905	COG0163	prenyltransferase activity
HV292_RS07930	COG4160	amino acid transport
HV292_RS07935	COG4598	ABC transporter
HV292_RS07950	COG1090	epimerase
HV292_RS07955	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV292_RS07960	COG0625	glutathione transferase activity
HV292_RS07965	COG0625	glutathione transferase activity
HV292_RS07970	COG0622	Phosphoesterase
HV292_RS07975	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HV292_RS07980	COG0280	phosphate acetyltransferase
HV292_RS07980	COG0857	belongs to the CobB CobQ family
HV292_RS08000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV292_RS08005	COG0471	metal ion transport
HV292_RS08005	COG0490	domain, Protein
HV292_RS08015	COG0436	Aminotransferase
HV292_RS08020	COG3039	Transposase
HV292_RS08025	COG0583	DNA-binding transcription factor activity
HV292_RS08070	COG0839	Belongs to the complex I subunit 6 family
HV292_RS08080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HV292_RS08085	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV292_RS08100	COG2153	protein acetylation
HV292_RS08105	COG1169	isochorismate synthase
HV292_RS08130	COG0318	PFAM AMP-dependent synthetase and ligase
HV292_RS08140	COG5464	transposase or invertase
HV292_RS08155	COG1414	Transcriptional regulator
HV292_RS08165	COG2271	Major facilitator Superfamily
HV292_RS08175	COG0247	lactate metabolic process
HV292_RS08185	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV292_RS08190	COG2271	Major facilitator Superfamily
HV292_RS08195	COG0584	glycerophosphoryl diester phosphodiesterase
HV292_RS08200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV292_RS08225	COG0784	Response regulator, receiver
HV292_RS08225	COG2205	protein histidine kinase activity
HV292_RS08235	COG0642	Histidine kinase
HV292_RS08235	COG2198	Histidine kinase
HV292_RS08250	COG2169	Transcriptional regulator
HV292_RS08250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HV292_RS08255	COG3145	DNA-N1-methyladenine dioxygenase activity
HV292_RS08260	COG4615	Cyclic peptide transporter
HV292_RS08265	COG2239	Acts as a magnesium transporter
HV292_RS08270	COG0659	secondary active sulfate transmembrane transporter activity
HV292_RS08310	COG1349	DNA-binding transcription factor activity
HV292_RS08315	COG0494	nUDIX hydrolase
HV292_RS08335	COG1061	Type III restriction enzyme res subunit
HV292_RS08340	COG1187	pseudouridine synthase activity
HV292_RS08345	COG2814	Major facilitator Superfamily
HV292_RS08355	COG4172	Belongs to the ABC transporter superfamily
HV292_RS08360	COG4239	(ABC) transporter, permease
HV292_RS08365	COG4174	ABC transporter (Permease)
HV292_RS08370	COG4166	transmembrane transport
HV292_RS08375	COG2200	EAL domain
HV292_RS08380	COG0791	NLP P60 protein
HV292_RS08385	COG0671	phosphoesterase, PA-phosphatase related
HV292_RS08390	COG0523	cobalamin synthesis protein
HV292_RS08395	COG0246	Mannitol dehydrogenase
HV292_RS08400	COG1312	Catalyzes the dehydration of D-mannonate
HV292_RS08425	COG1566	PFAM secretion protein HlyD family protein
HV292_RS08430	COG2814	Major facilitator Superfamily
HV292_RS08440	COG1105	Belongs to the carbohydrate kinase PfkB family
HV292_RS08445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV292_RS08445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV292_RS08445	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HV292_RS08455	COG2855	membrane
HV292_RS08460	COG0583	DNA-binding transcription factor activity
HV292_RS08465	COG0833	amino acid
HV292_RS08470	COG4771	TonB-dependent receptor
HV292_RS08485	COG2311	Membrane
HV292_RS08500	COG1129	ABC transporter
HV292_RS08520	COG2949	membrane
HV292_RS08530	COG1346	cytolysis
HV292_RS08540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV292_RS08545	COG3659	wide pore channel activity
HV292_RS08560	COG2723	6-phospho-beta-galactosidase activity
HV292_RS08570	COG1538	Outer membrane efflux protein
HV292_RS08575	COG0586	Pfam SNARE associated Golgi protein
HV292_RS08585	COG1686	Belongs to the peptidase S11 family
HV292_RS08600	COG0277	FAD linked oxidase domain protein
HV292_RS08605	COG1472	Belongs to the glycosyl hydrolase 3 family
HV292_RS08610	COG1732	Glycine betaine
HV292_RS08615	COG1174	glycine betaine transport
HV292_RS08620	COG1125	glycine betaine transport
HV292_RS08625	COG1174	glycine betaine transport
HV292_RS08635	COG3275	phosphorelay sensor kinase activity
HV292_RS08645	COG4807	Protein conserved in bacteria
HV292_RS08665	COG5455	response to cobalt ion
HV292_RS08670	COG0583	DNA-binding transcription factor activity
HV292_RS08675	COG2252	PERMEase
HV292_RS08685	COG0583	DNA-binding transcription factor activity
HV292_RS08700	COG3039	Transposase
HV292_RS08730	COG3039	Transposase
HV292_RS08755	COG0351	phosphomethylpyrimidine kinase
HV292_RS08760	COG1830	Aldolase
HV292_RS08775	COG1070	Carbohydrate kinase
HV292_RS08785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV292_RS08790	COG4948	Mandelate Racemase Muconate Lactonizing
HV292_RS08795	COG0747	negative chemotaxis
HV292_RS08800	COG0601	transmembrane transport
HV292_RS08810	COG0444	Belongs to the ABC transporter superfamily
HV292_RS08815	COG4608	Belongs to the ABC transporter superfamily
HV292_RS08830	COG0745	RESPONSE REGULATOR receiver
HV292_RS08835	COG2205	protein histidine kinase activity
HV292_RS08860	COG1301	dicarboxylic acid transport
HV292_RS08875	COG0745	RESPONSE REGULATOR receiver
HV292_RS08880	COG5002	protein histidine kinase activity
HV292_RS08885	COG0443	Heat shock 70 kDa protein
HV292_RS08890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HV292_RS08905	COG2982	Protein involved in outer membrane biogenesis
HV292_RS08910	COG1253	flavin adenine dinucleotide binding
HV292_RS08960	COG0438	transferase activity, transferring glycosyl groups
HV292_RS08975	COG1215	transferase activity, transferring glycosyl groups
HV292_RS08985	COG2244	polysaccharide biosynthetic process
HV292_RS09050	COG0438	transferase activity, transferring glycosyl groups
HV292_RS09055	COG1215	transferase activity, transferring glycosyl groups
HV292_RS09075	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HV292_RS09105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV292_RS09110	COG0583	DNA-binding transcription factor activity
HV292_RS09120	COG0531	amino acid
HV292_RS09125	COG0640	Transcriptional regulator
HV292_RS09130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HV292_RS09135	COG2925	Exonuclease
HV292_RS09145	COG3344	reverse transcriptase
HV292_RS09155	COG1289	transmembrane transporter activity
HV292_RS09175	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HV292_RS09185	COG1942	4-Oxalocrotonate Tautomerase
HV292_RS09190	COG0583	DNA-binding transcription factor activity
HV292_RS09195	COG0095	Lipoate-protein ligase
HV292_RS09200	COG0477	Major facilitator Superfamily
HV292_RS09210	COG5001	Diguanylate cyclase
HV292_RS09210	COG3300	MHYT domain
HV292_RS09215	COG3615	Tellurite resistance protein tehB
HV292_RS09240	COG3706	GGDEF domain
HV292_RS09255	COG0534	Mate efflux family protein
HV292_RS09265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HV292_RS09285	COG0604	alcohol dehydrogenase
HV292_RS09290	COG1309	transcriptional regulator
HV292_RS09295	COG0025	NhaP-type Na H and K H
HV292_RS09325	COG0251	oxidation-reduction process
HV292_RS09345	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV292_RS09355	COG1418	mRNA catabolic process
HV292_RS09360	COG0270	DNA (cytosine-5-)-methyltransferase activity
HV292_RS09365	COG3727	T/G mismatch-specific endonuclease activity
HV292_RS09370	COG0697	spore germination
HV292_RS09375	COG2354	Protein conserved in bacteria
HV292_RS09405	COG0366	Alpha amylase catalytic
HV292_RS09430	COG2197	response regulator
HV292_RS09440	COG2197	response regulator
HV292_RS09475	COG3012	SEC-C Motif Domain Protein
HV292_RS09475	COG3318	Belongs to the UPF0149 family
HV292_RS09480	COG0814	amino acid
HV292_RS09490	COG1528	Iron-storage protein
HV292_RS09505	COG0477	Major facilitator Superfamily
HV292_RS09515	COG2211	Major facilitator Superfamily
HV292_RS09525	COG1528	Iron-storage protein
HV292_RS09535	COG1879	ABC-type sugar transport system periplasmic component
HV292_RS09545	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS09570	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV292_RS09580	COG3102	Protein conserved in bacteria
HV292_RS09590	COG3385	transposase activity
HV292_RS09610	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HV292_RS09615	COG1801	Protein of unknown function DUF72
HV292_RS09620	COG1335	isochorismatase
HV292_RS09630	COG0494	nUDIX hydrolase
HV292_RS09655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV292_RS09665	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HV292_RS09670	COG0739	heme binding
HV292_RS09675	COG1560	Kdo2-lipid A biosynthetic process
HV292_RS09685	COG1737	Transcriptional regulator
HV292_RS09695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HV292_RS09700	COG0129	dihydroxy-acid dehydratase activity
HV292_RS09705	COG0800	Aldolase
HV292_RS09715	COG3141	response to X-ray
HV292_RS09720	COG2979	Protein of unknown function (DUF533)
HV292_RS09725	COG1770	oligopeptidase
HV292_RS09730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV292_RS09740	COG2372	response to copper ion
HV292_RS09745	COG1276	copper resistance
HV292_RS09790	COG2990	Protein conserved in bacteria
HV292_RS09815	COG3008	intermembrane lipid transfer
HV292_RS09820	COG2995	paraquat-inducible protein a
HV292_RS09825	COG1956	GAF domain-containing protein
HV292_RS09845	COG2814	Major facilitator Superfamily
HV292_RS09850	COG1414	Transcriptional regulator
HV292_RS09880	COG0768	penicillin binding
HV292_RS09885	COG2226	methyltransferase
HV292_RS09900	COG3716	PTS system mannose fructose sorbose family IID component
HV292_RS09905	COG3715	PTS system
HV292_RS09910	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV292_RS09910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV292_RS09915	COG1253	flavin adenine dinucleotide binding
HV292_RS09920	COG2200	EAL domain
HV292_RS09925	COG1760	l-serine dehydratase
HV292_RS09945	COG0251	oxidation-reduction process
HV292_RS09950	COG1199	ATP-dependent helicase activity
HV292_RS09960	COG3065	identical protein binding
HV292_RS09970	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HV292_RS09980	COG2894	cell division
HV292_RS09995	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV292_RS10025	COG2719	SpoVR family
HV292_RS10050	COG1619	proteins homologs of microcin C7 resistance protein MccF
HV292_RS10075	COG2308	Evidence 4 Homologs of previously reported genes of
HV292_RS10115	COG0583	DNA-binding transcription factor activity
HV292_RS10120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV292_RS10135	COG1882	Formate acetyltransferase
HV292_RS10170	COG0583	DNA-binding transcription factor activity
HV292_RS10200	COG0583	DNA-binding transcription factor activity
HV292_RS10215	COG3122	Protein conserved in bacteria
HV292_RS10235	COG2885	chlorophyll binding
HV292_RS10245	COG3501	Rhs element vgr protein
HV292_RS10255	COG3039	Transposase
HV292_RS10270	COG3039	Transposase
HV292_RS10285	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HV292_RS10300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HV292_RS10365	COG0012	GTP binding
HV292_RS10385	COG0659	secondary active sulfate transmembrane transporter activity
HV292_RS10415	COG2890	protein-(glutamine-N5) methyltransferase activity
HV292_RS10435	COG0387	Pfam Sodium calcium exchanger
HV292_RS10440	COG4572	Cation transport regulator
HV292_RS10445	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HV292_RS10455	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HV292_RS10460	COG3707	response regulator
HV292_RS10465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV292_RS10470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV292_RS10475	COG1116	anion transmembrane transporter activity
HV292_RS10480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV292_RS10480	COG2146	nitrite reductase [NAD(P)H] activity
HV292_RS10485	COG0243	molybdopterin cofactor binding
HV292_RS10490	COG4932	domain protein
HV292_RS10495	COG2197	response regulator
HV292_RS10500	COG3850	Histidine kinase
HV292_RS10505	COG2223	nitrite transmembrane transporter activity
HV292_RS10515	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV292_RS10520	COG1140	nitrate reductase beta subunit
HV292_RS10525	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV292_RS10530	COG2181	nitrate reductase activity
HV292_RS10540	COG1522	sequence-specific DNA binding
HV292_RS10580	COG0788	formyltetrahydrofolate deformylase activity
HV292_RS10595	COG0745	RESPONSE REGULATOR receiver
HV292_RS10600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HV292_RS10605	COG2916	Histone family protein nucleoid-structuring protein H-NS
HV292_RS10615	COG1435	thymidine kinase activity
HV292_RS10620	COG1454	alcohol dehydrogenase
HV292_RS10620	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS10630	COG2095	MarC family integral membrane protein
HV292_RS10635	COG4166	transmembrane transport
HV292_RS10640	COG0601	transmembrane transport
HV292_RS10645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV292_RS10650	COG0444	Belongs to the ABC transporter superfamily
HV292_RS10660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV292_RS10680	COG2353	YceI-like domain
HV292_RS10690	COG2350	Protein conserved in bacteria
HV292_RS10700	COG3001	Fructosamine kinase
HV292_RS10710	COG1105	Belongs to the carbohydrate kinase PfkB family
HV292_RS10715	COG3137	Salt-induced outer membrane protein
HV292_RS10755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HV292_RS10755	COG0072	phenylalanine-tRNA ligase activity
HV292_RS10775	COG0583	DNA-binding transcription factor activity
HV292_RS10795	COG0386	Belongs to the glutathione peroxidase family
HV292_RS10805	COG0791	NLP P60 protein
HV292_RS10815	COG4256	Hemin uptake protein
HV292_RS10820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV292_RS10835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV292_RS10835	COG0574	Belongs to the PEP-utilizing enzyme family
HV292_RS10845	COG0628	permease
HV292_RS10850	COG0277	FAD linked oxidase domain protein
HV292_RS10850	COG0247	lactate metabolic process
HV292_RS10855	COG2050	protein possibly involved in aromatic compounds catabolism
HV292_RS10860	COG2261	transglycosylase associated protein
HV292_RS10885	COG1120	ATPase activity
HV292_RS10890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV292_RS10900	COG0583	DNA-binding transcription factor activity
HV292_RS10925	COG1304	FMN binding
HV292_RS10930	COG1309	transcriptional regulator
HV292_RS10950	COG0316	Belongs to the HesB IscA family
HV292_RS10955	COG0719	Fe-S assembly protein
HV292_RS10960	COG0396	ATPase activity
HV292_RS10965	COG0719	Fe-S assembly protein
HV292_RS10980	COG1376	ErfK ybiS ycfS ynhG family protein
HV292_RS11010	COG1309	transcriptional regulator
HV292_RS11020	COG2271	Major facilitator Superfamily
HV292_RS11025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV292_RS11050	COG1414	Transcriptional regulator
HV292_RS11085	COG2814	Major facilitator Superfamily
HV292_RS11105	COG0583	DNA-binding transcription factor activity
HV292_RS11110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV292_RS11130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV292_RS11135	COG1116	anion transmembrane transporter activity
HV292_RS11140	COG4774	siderophore transport
HV292_RS11145	COG1120	ATPase activity
HV292_RS11150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV292_RS11155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV292_RS11175	COG0765	amino acid transport
HV292_RS11180	COG1126	abc transporter atp-binding protein
HV292_RS11220	COG3383	formate dehydrogenase (NAD+) activity
HV292_RS11225	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV292_RS11235	COG1175	transmembrane transport
HV292_RS11265	COG4133	protoheme IX ABC transporter activity
HV292_RS11270	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HV292_RS11275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HV292_RS11290	COG1138	Cytochrome C-type biogenesis protein
HV292_RS11295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HV292_RS11300	COG3088	subunit of a heme lyase
HV292_RS11300	COG4235	cytochrome complex assembly
HV292_RS11320	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HV292_RS11335	COG5002	protein histidine kinase activity
HV292_RS11335	COG3850	Histidine kinase
HV292_RS11340	COG0745	RESPONSE REGULATOR receiver
HV292_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS11405	COG2610	gluconate transmembrane transporter activity
HV292_RS11410	COG1250	3-hydroxyacyl-CoA dehydrogenase
HV292_RS11420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HV292_RS11430	COG0583	DNA-binding transcription factor activity
HV292_RS11460	COG2814	Major facilitator Superfamily
HV292_RS11475	COG0277	FAD linked oxidase domain protein
HV292_RS11480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV292_RS11505	COG0402	S-adenosylhomocysteine deaminase activity
HV292_RS11515	COG0583	DNA-binding transcription factor activity
HV292_RS11560	COG4608	Belongs to the ABC transporter superfamily
HV292_RS11565	COG0444	Belongs to the ABC transporter superfamily
HV292_RS11590	COG0346	lactoylglutathione lyase activity
HV292_RS11595	COG1349	DNA-binding transcription factor activity
HV292_RS11630	COG3039	Transposase
HV292_RS11650	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HV292_RS11655	COG3039	Transposase
HV292_RS11690	COG0307	riboflavin synthase, alpha
HV292_RS11695	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV292_RS11700	COG2814	Major facilitator Superfamily
HV292_RS11705	COG0583	DNA-binding transcription factor activity
HV292_RS11720	COG2814	Major facilitator Superfamily
HV292_RS11735	COG0791	NLP P60 protein
HV292_RS11740	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HV292_RS11750	COG0346	lactoylglutathione lyase activity
HV292_RS11755	COG1902	pentaerythritol trinitrate reductase activity
HV292_RS11760	COG1309	transcriptional regulator
HV292_RS11765	COG3313	Fe-S protein
HV292_RS11770	COG4989	oxidoreductase activity
HV292_RS11775	COG2032	superoxide dismutase activity
HV292_RS11780	COG1289	transmembrane transporter activity
HV292_RS11785	COG1566	PFAM secretion protein HlyD family protein
HV292_RS11800	COG3706	GGDEF domain
HV292_RS11815	COG3895	Periplasmic Protein
HV292_RS11830	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HV292_RS11835	COG0625	glutathione transferase activity
HV292_RS11845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HV292_RS11855	COG4659	FMN binding
HV292_RS11890	COG2723	6-phospho-beta-galactosidase activity
HV292_RS11900	COG0673	inositol 2-dehydrogenase activity
HV292_RS11910	COG2814	Major facilitator Superfamily
HV292_RS11930	COG3038	cytochrome b561
HV292_RS11950	COG0583	DNA-binding transcription factor activity
HV292_RS11955	COG3485	protocatechuate 3,4-dioxygenase
HV292_RS11960	COG3485	protocatechuate 3,4-dioxygenase
HV292_RS11965	COG5383	Protein conserved in bacteria
HV292_RS11970	COG2272	Belongs to the type-B carboxylesterase lipase family
HV292_RS11985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV292_RS11990	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV292_RS11995	COG1275	C4-dicarboxylate transporter malic acid transport protein
HV292_RS12000	COG0500	methyltransferase
HV292_RS12015	COG3708	Transcriptional regulator
HV292_RS12015	COG2207	Transcriptional regulator
HV292_RS12020	COG3135	benzoate transporter
HV292_RS12025	COG1396	sequence-specific DNA binding
HV292_RS12035	COG0826	peptidase U32
HV292_RS12055	COG1294	oxidase, subunit
HV292_RS12060	COG1271	oxidase subunit
HV292_RS12065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV292_RS12070	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV292_RS12075	COG3842	ATPase activity
HV292_RS12080	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV292_RS12085	COG1177	transmembrane transport
HV292_RS12090	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS12125	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS12130	COG0747	negative chemotaxis
HV292_RS12140	COG3238	Protein conserved in bacteria
HV292_RS12145	COG1247	-acetyltransferase
HV292_RS12170	COG3691	Protein conserved in bacteria
HV292_RS12175	COG1228	amidohydrolase
HV292_RS12180	COG4772	TonB-dependent receptor
HV292_RS12205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HV292_RS12210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV292_RS12215	COG1473	amidohydrolase
HV292_RS12220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV292_RS12235	COG0765	amino acid transport
HV292_RS12240	COG1126	abc transporter atp-binding protein
HV292_RS12250	COG2271	Major facilitator Superfamily
HV292_RS12260	COG1609	Transcriptional regulator
HV292_RS12265	COG0625	glutathione transferase activity
HV292_RS12275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV292_RS12280	COG3842	ATPase activity
HV292_RS12285	COG1840	ABC-type Fe3 transport system, periplasmic component
HV292_RS12290	COG1178	ABC-type Fe3 transport system permease component
HV292_RS12295	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HV292_RS12300	COG2181	nitrate reductase activity
HV292_RS12305	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV292_RS12310	COG1140	nitrate reductase beta subunit
HV292_RS12315	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV292_RS12320	COG2223	nitrite transmembrane transporter activity
HV292_RS12335	COG1414	Transcriptional regulator
HV292_RS12340	COG4948	Mandelate Racemase Muconate Lactonizing
HV292_RS12345	COG4829	muconolactone delta-isomerase
HV292_RS12350	COG3485	protocatechuate 3,4-dioxygenase
HV292_RS12360	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HV292_RS12375	COG0697	spore germination
HV292_RS12385	COG0437	4 iron, 4 sulfur cluster binding
HV292_RS12390	COG2864	formate dehydrogenase
HV292_RS12405	COG2326	polyphosphate kinase activity
HV292_RS12415	COG2814	Major facilitator Superfamily
HV292_RS12425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV292_RS12445	COG0747	negative chemotaxis
HV292_RS12450	COG1064	alcohol dehydrogenase
HV292_RS12465	COG0488	(ABC) transporter
HV292_RS12505	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS12510	COG3729	General stress protein
HV292_RS12520	COG3685	Protein conserved in bacteria
HV292_RS12530	COG0366	Alpha amylase catalytic
HV292_RS12540	COG2323	membrane
HV292_RS12550	COG3111	PFAM Bacterial OB fold (BOF) protein
HV292_RS12560	COG1764	response to oxidative stress
HV292_RS12585	COG3781	membrane
HV292_RS12590	COG0243	molybdopterin cofactor binding
HV292_RS12595	COG0583	DNA-binding transcription factor activity
HV292_RS12600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV292_RS12610	COG3039	Transposase
HV292_RS12635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV292_RS12640	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV292_RS12645	COG2814	Major facilitator Superfamily
HV292_RS12650	COG1285	pathogenesis
HV292_RS12655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HV292_RS12665	COG0583	DNA-binding transcription factor activity
HV292_RS12685	COG0519	Catalyzes the synthesis of GMP from XMP
HV292_RS12685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HV292_RS12725	COG0596	Alpha beta hydrolase
HV292_RS12730	COG0745	RESPONSE REGULATOR receiver
HV292_RS12735	COG2205	protein histidine kinase activity
HV292_RS12745	COG0583	DNA-binding transcription factor activity
HV292_RS12750	COG0076	glutamate decarboxylase activity
HV292_RS12755	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV292_RS12760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV292_RS12765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV292_RS12770	COG1116	anion transmembrane transporter activity
HV292_RS12775	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HV292_RS12790	COG0673	inositol 2-dehydrogenase activity
HV292_RS12800	COG1609	Transcriptional regulator
HV292_RS12805	COG3706	GGDEF domain
HV292_RS12810	COG0402	S-adenosylhomocysteine deaminase activity
HV292_RS12815	COG1953	Uracil, thiamine, allantoin
HV292_RS12850	COG0596	Alpha beta hydrolase
HV292_RS12860	COG2207	Transcriptional regulator
HV292_RS12875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV292_RS12955	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HV292_RS12965	COG2070	2-Nitropropane dioxygenase
HV292_RS12970	COG0583	DNA-binding transcription factor activity
HV292_RS12980	COG1902	pentaerythritol trinitrate reductase activity
HV292_RS12985	COG4529	Protein conserved in bacteria
HV292_RS12990	COG0477	Major facilitator Superfamily
HV292_RS13020	COG2223	nitrite transmembrane transporter activity
HV292_RS13030	COG1609	Transcriptional regulator
HV292_RS13035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV292_RS13045	COG3037	sugar-specific permease SgaT UlaA
HV292_RS13050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV292_RS13060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV292_RS13065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV292_RS13065	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HV292_RS13065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV292_RS13080	COG0583	DNA-binding transcription factor activity
HV292_RS13085	COG0583	DNA-binding transcription factor activity
HV292_RS13090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV292_RS13100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV292_RS13115	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS13125	COG1609	Transcriptional regulator
HV292_RS13155	COG1652	LysM domain
HV292_RS13180	COG0456	acetyltransferase
HV292_RS13180	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HV292_RS13190	COG0667	Aldo Keto reductase
HV292_RS13195	COG0667	Aldo Keto reductase
HV292_RS13200	COG3386	PFAM SMP-30 Gluconolaconase
HV292_RS13205	COG0667	Aldo Keto reductase
HV292_RS13210	COG3039	Transposase
HV292_RS13225	COG2801	Transposase and inactivated derivatives
HV292_RS13255	COG4977	sequence-specific DNA binding
HV292_RS13275	COG4977	sequence-specific DNA binding
HV292_RS13280	COG1349	DNA-binding transcription factor activity
HV292_RS13295	COG1349	DNA-binding transcription factor activity
HV292_RS13300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV292_RS13305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV292_RS13310	COG0738	Major facilitator superfamily
HV292_RS13355	COG1929	Belongs to the glycerate kinase type-1 family
HV292_RS13360	COG3835	regulator
HV292_RS13370	COG0583	DNA-binding transcription factor activity
HV292_RS13380	COG2186	Transcriptional regulator
HV292_RS13385	COG1263	PTS System
HV292_RS13385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV292_RS13395	COG2814	Major facilitator Superfamily
HV292_RS13400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV292_RS13400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV292_RS13415	COG2819	hydrolase of the alpha beta superfamily
HV292_RS13420	COG5001	Diguanylate cyclase
HV292_RS13420	COG3300	MHYT domain
HV292_RS13455	COG3188	usher protein
HV292_RS13470	COG3550	peptidyl-serine autophosphorylation
HV292_RS13475	COG1396	sequence-specific DNA binding
HV292_RS13480	COG2351	hydroxyisourate hydrolase activity
HV292_RS13485	COG3648	Uricase
HV292_RS13485	COG3195	allantoin biosynthetic process
HV292_RS13490	COG2233	PERMEase
HV292_RS13520	COG2207	Transcriptional regulator
HV292_RS13535	COG4628	conserved protein (DUF2132)
HV292_RS13555	COG2011	ABC-type metal ion transport system permease component
HV292_RS13560	COG2070	2-Nitropropane dioxygenase
HV292_RS13570	COG0477	Major facilitator Superfamily
HV292_RS13620	COG2199	diguanylate cyclase activity
HV292_RS13635	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS13640	COG0583	DNA-binding transcription factor activity
HV292_RS13650	COG0039	L-malate dehydrogenase activity
HV292_RS13655	COG1349	DNA-binding transcription factor activity
HV292_RS13660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HV292_RS13665	COG3395	kinase activity
HV292_RS13675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV292_RS13680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV292_RS13685	COG2271	Major facilitator Superfamily
HV292_RS13715	COG4977	sequence-specific DNA binding
HV292_RS13725	COG0697	spore germination
HV292_RS13730	COG2814	Major facilitator Superfamily
HV292_RS13745	COG1129	ABC transporter
HV292_RS13760	COG0683	leucine binding
HV292_RS13765	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HV292_RS13855	COG3409	Peptidoglycan-binding domain 1 protein
HV292_RS13855	COG3267	Type II secretory pathway component ExeA
HV292_RS13900	COG0741	lytic transglycosylase activity
HV292_RS13925	COG4373	Mu-like prophage FluMu protein gp28
HV292_RS14035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV292_RS14045	COG2223	nitrite transmembrane transporter activity
HV292_RS14050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HV292_RS14065	COG1349	DNA-binding transcription factor activity
HV292_RS14070	COG2084	Dehydrogenase
HV292_RS14075	COG3395	kinase activity
HV292_RS14080	COG0235	Class ii aldolase
HV292_RS14090	COG3039	Transposase
HV292_RS14095	COG0339	signal peptide processing
HV292_RS14100	COG4221	oxidoreductase activity
HV292_RS14105	COG1802	Transcriptional regulator
HV292_RS14110	COG0589	response to stress
HV292_RS14115	COG0246	Mannitol dehydrogenase
HV292_RS14120	COG2271	Major facilitator Superfamily
HV292_RS14135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV292_RS14155	COG3039	Transposase
HV292_RS14165	COG0437	4 iron, 4 sulfur cluster binding
HV292_RS14170	COG3302	dmso reductase anchor subunit
HV292_RS14185	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HV292_RS14190	COG1940	carbohydrate kinase activity
HV292_RS14195	COG0583	DNA-binding transcription factor activity
HV292_RS14200	COG2814	Major facilitator Superfamily
HV292_RS14205	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HV292_RS14215	COG3591	Belongs to the peptidase S1B family
HV292_RS14235	COG0628	permease
HV292_RS14265	COG0679	Auxin Efflux Carrier
HV292_RS14275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HV292_RS14300	COG3290	protein histidine kinase activity
HV292_RS14305	COG4565	transcriptional regulatory protein
HV292_RS14325	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV292_RS14325	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV292_RS14335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV292_RS14340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HV292_RS14350	COG0183	Belongs to the thiolase family
HV292_RS14355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HV292_RS14365	COG1414	Transcriptional regulator
HV292_RS14370	COG2840	Smr protein MutS2
HV292_RS14375	COG0583	DNA-binding transcription factor activity
HV292_RS14385	COG1473	amidohydrolase
HV292_RS14390	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HV292_RS14405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV292_RS14420	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HV292_RS14425	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HV292_RS14440	COG0531	amino acid
HV292_RS14450	COG3136	membrane protein required for alginate biosynthesis
HV292_RS14455	COG0745	RESPONSE REGULATOR receiver
HV292_RS14465	COG2205	protein histidine kinase activity
HV292_RS14475	COG0114	fumarate hydratase activity
HV292_RS14480	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV292_RS14480	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV292_RS14485	COG1482	cell wall glycoprotein biosynthetic process
HV292_RS14490	COG5339	Protein conserved in bacteria
HV292_RS14495	COG1609	Transcriptional regulator
HV292_RS14500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV292_RS14500	COG1263	PTS System
HV292_RS14505	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV292_RS14530	COG2391	methyltransferase activity
HV292_RS14535	COG0425	Belongs to the sulfur carrier protein TusA family
HV292_RS14540	COG5562	phage envelope protein
HV292_RS14545	COG0401	homolog of Blt101
HV292_RS14550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HV292_RS14555	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS14565	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV292_RS14570	COG0477	Major facilitator Superfamily
HV292_RS14575	COG1113	amino acid transport
HV292_RS14580	COG2988	succinylglutamate desuccinylase activity
HV292_RS14585	COG3724	N-succinylarginine dihydrolase activity
HV292_RS14590	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS14595	COG3138	arginine N-succinyltransferase
HV292_RS14600	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HV292_RS14610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HV292_RS14615	COG0667	Aldo Keto reductase
HV292_RS14620	COG0583	DNA-binding transcription factor activity
HV292_RS14645	COG4122	O-methyltransferase activity
HV292_RS14650	COG1643	Atp-dependent helicase
HV292_RS14665	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV292_RS14670	COG3327	negative regulation of DNA-templated transcription, initiation
HV292_RS14675	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HV292_RS14680	COG0183	Belongs to the thiolase family
HV292_RS14685	COG2050	protein possibly involved in aromatic compounds catabolism
HV292_RS14690	COG1250	3-hydroxyacyl-CoA dehydrogenase
HV292_RS14695	COG1024	Enoyl-CoA hydratase
HV292_RS14700	COG1024	Enoyl-CoA hydratase
HV292_RS14705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV292_RS14710	COG2151	metal-sulfur cluster biosynthetic enzyme
HV292_RS14715	COG3396	Phenylacetate-CoA oxygenase
HV292_RS14720	COG3460	Phenylacetate-CoA oxygenase
HV292_RS14725	COG3396	Phenylacetate-CoA oxygenase
HV292_RS14730	COG2030	dehydratase
HV292_RS14730	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS14750	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS14755	COG2207	Transcriptional regulator
HV292_RS14760	COG3784	Protein of unknown function (DUF1318)
HV292_RS14770	COG2911	Protein conserved in bacteria
HV292_RS14775	COG0586	Pfam SNARE associated Golgi protein
HV292_RS14780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HV292_RS14785	COG3187	Heat shock protein
HV292_RS14790	COG3042	response to heat
HV292_RS14795	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HV292_RS14795	COG1013	pyruvate-flavodoxin oxidoreductase activity
HV292_RS14795	COG0674	pyruvate-flavodoxin oxidoreductase activity
HV292_RS14795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV292_RS14800	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV292_RS14810	COG0589	response to stress
HV292_RS14820	COG0513	Belongs to the DEAD box helicase family
HV292_RS14830	COG1349	DNA-binding transcription factor activity
HV292_RS14835	COG0673	inositol 2-dehydrogenase activity
HV292_RS14850	COG1113	amino acid transport
HV292_RS14855	COG1522	sequence-specific DNA binding
HV292_RS14870	COG2011	ABC-type metal ion transport system permease component
HV292_RS14875	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HV292_RS14880	COG1464	Belongs to the NlpA lipoprotein family
HV292_RS14885	COG0436	Aminotransferase
HV292_RS14890	COG0604	alcohol dehydrogenase
HV292_RS14920	COG0583	DNA-binding transcription factor activity
HV292_RS14940	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS14945	COG1309	transcriptional regulator
HV292_RS14950	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS15030	COG2885	chlorophyll binding
HV292_RS15125	COG1484	DNA-dependent DNA replication
HV292_RS15205	COG0582	viral genome integration into host DNA
HV292_RS15210	COG0693	protein deglycase activity
HV292_RS15215	COG1078	dGTPase activity
HV292_RS15220	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS15225	COG0583	DNA-binding transcription factor activity
HV292_RS15245	COG0656	L-ascorbic acid biosynthetic process
HV292_RS15275	COG4166	transmembrane transport
HV292_RS15285	COG2866	Carboxypeptidase
HV292_RS15290	COG4948	Mandelate Racemase Muconate Lactonizing
HV292_RS15295	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HV292_RS15300	COG3180	Ammonia monooxygenase
HV292_RS15310	COG1486	melibiose metabolic process
HV292_RS15315	COG0583	DNA-binding transcription factor activity
HV292_RS15325	COG3106	COG3106 Predicted ATPase
HV292_RS15335	COG1983	PspC domain protein
HV292_RS15345	COG1842	Phage shock protein A
HV292_RS15350	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV292_RS15360	COG1473	amidohydrolase
HV292_RS15375	COG0702	epimerase
HV292_RS15390	COG4171	peptide transport system, permease
HV292_RS15405	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HV292_RS15415	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HV292_RS15420	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV292_RS15420	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV292_RS15435	COG1349	DNA-binding transcription factor activity
HV292_RS15445	COG0023	Translation Initiation Factor
HV292_RS15455	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HV292_RS15460	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HV292_RS15465	COG0671	phosphoesterase, PA-phosphatase related
HV292_RS15475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HV292_RS15500	COG0616	signal peptide processing
HV292_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS15515	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HV292_RS15525	COG0583	DNA-binding transcription factor activity
HV292_RS15535	COG0009	L-threonylcarbamoyladenylate synthase
HV292_RS15545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HV292_RS15550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV292_RS15550	COG0512	Glutamine amidotransferase of anthranilate synthase
HV292_RS15555	COG0134	indole-3-glycerol-phosphate synthase activity
HV292_RS15555	COG0135	phosphoribosylanthranilate isomerase activity
HV292_RS15610	COG4774	siderophore transport
HV292_RS15620	COG3047	cAMP biosynthetic process
HV292_RS15625	COG0727	PFAM Uncharacterised protein family (UPF0153)
HV292_RS15655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV292_RS15660	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS15665	COG1988	membrane-bound metal-dependent
HV292_RS15680	COG0753	catalase activity
HV292_RS15690	COG1486	melibiose metabolic process
HV292_RS15695	COG1917	Cupin 2, conserved barrel domain protein
HV292_RS15695	COG2169	Transcriptional regulator
HV292_RS15700	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV292_RS15705	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV292_RS15715	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV292_RS15720	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV292_RS15730	COG0322	excinuclease ABC activity
HV292_RS15735	COG3678	ATP-independent chaperone mediated protein folding
HV292_RS15745	COG3724	N-succinylarginine dihydrolase activity
HV292_RS15755	COG3138	arginine N-succinyltransferase
HV292_RS15765	COG0708	Exodeoxyribonuclease III
HV292_RS15770	COG0398	Pfam SNARE associated Golgi protein
HV292_RS15775	COG0398	Pfam SNARE associated Golgi protein
HV292_RS15780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV292_RS15785	COG4134	Bacterial extracellular solute-binding protein
HV292_RS15790	COG4135	transport system, permease component
HV292_RS15795	COG4136	ATPase activity
HV292_RS15800	COG2897	thiosulfate sulfurtransferase activity
HV292_RS15805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HV292_RS15810	COG0494	nUDIX hydrolase
HV292_RS15815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HV292_RS15820	COG0604	alcohol dehydrogenase
HV292_RS15820	COG3321	synthase
HV292_RS15820	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS15825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HV292_RS15830	COG0709	Synthesizes selenophosphate from selenide and ATP
HV292_RS15840	COG0778	Nitroreductase
HV292_RS15845	COG0616	signal peptide processing
HV292_RS15850	COG0252	asparaginase activity
HV292_RS15855	COG1335	isochorismatase
HV292_RS15870	COG3139	Protein of unknown function (DUF1315)
HV292_RS15890	COG0656	L-ascorbic acid biosynthetic process
HV292_RS15895	COG3713	MltA-interacting MipA family protein
HV292_RS15900	COG2766	serine protein kinase
HV292_RS15915	COG0386	Belongs to the glutathione peroxidase family
HV292_RS15940	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS15945	COG0583	DNA-binding transcription factor activity
HV292_RS15950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HV292_RS15955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HV292_RS15960	COG3344	reverse transcriptase
HV292_RS15965	COG3344	reverse transcriptase
HV292_RS15975	COG0859	PFAM glycosyl transferase family 9
HV292_RS15980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV292_RS15990	COG2207	Transcriptional regulator
HV292_RS15995	COG2807	transmembrane transport
HV292_RS16000	COG0504	CTP synthase activity
HV292_RS16005	COG1683	Conserved Protein
HV292_RS16010	COG3189	MarR family transcriptional regulator
HV292_RS16015	COG3042	response to heat
HV292_RS16020	COG2199	diguanylate cyclase activity
HV292_RS16020	COG2203	Gaf domain
HV292_RS16040	COG3182	Iron-regulated membrane protein
HV292_RS16050	COG1560	Kdo2-lipid A biosynthetic process
HV292_RS16060	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HV292_RS16065	COG3706	GGDEF domain
HV292_RS16070	COG0583	DNA-binding transcription factor activity
HV292_RS16075	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV292_RS16105	COG1294	oxidase, subunit
HV292_RS16110	COG1271	oxidase subunit
HV292_RS16115	COG3546	catalase activity
HV292_RS16120	COG3685	Protein conserved in bacteria
HV292_RS16125	COG3685	Protein conserved in bacteria
HV292_RS16130	COG3729	General stress protein
HV292_RS16135	COG1063	alcohol dehydrogenase
HV292_RS16140	COG3813	Protein conserved in bacteria
HV292_RS16160	COG0640	Transcriptional regulator
HV292_RS16165	COG0538	isocitrate dehydrogenase activity
HV292_RS16170	COG1187	pseudouridine synthase activity
HV292_RS16190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HV292_RS16210	COG2205	protein histidine kinase activity
HV292_RS16215	COG2850	peptidyl-arginine hydroxylation
HV292_RS16220	COG1943	Transposase
HV292_RS16240	COG1177	transmembrane transport
HV292_RS16255	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HV292_RS16265	COG0318	PFAM AMP-dependent synthetase and ligase
HV292_RS16275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HV292_RS16285	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV292_RS16295	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV292_RS16305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HV292_RS16310	COG1388	LysM domain
HV292_RS16310	COG1376	ErfK ybiS ycfS ynhG family protein
HV292_RS16325	COG1309	transcriptional regulator
HV292_RS16340	COG3134	Outer membrane lipoprotein
HV292_RS16345	COG1252	NADH dehydrogenase
HV292_RS16370	COG5633	Lipoprotein
HV292_RS16375	COG0537	adenosine 5'-monophosphoramidase activity
HV292_RS16385	COG0084	hydrolase, TatD family'
HV292_RS16390	COG0470	DNA polymerase III
HV292_RS16400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HV292_RS16405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV292_RS16410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV292_RS16425	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HV292_RS16445	COG1399	metal-binding, possibly nucleic acid-binding protein
HV292_RS16465	COG1530	ribonuclease E activity
HV292_RS16470	COG0583	DNA-binding transcription factor activity
HV292_RS16475	COG2814	Major facilitator Superfamily
HV292_RS16495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV292_RS16545	COG1560	Kdo2-lipid A biosynthetic process
HV292_RS16560	COG5645	(Lipo)protein
HV292_RS16595	COG3381	protein complex oligomerization
HV292_RS16615	COG0583	DNA-binding transcription factor activity
HV292_RS16625	COG1335	isochorismatase
HV292_RS16635	COG1702	phosphate starvation-inducible protein PhoH
HV292_RS16655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV292_RS16665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV292_RS16680	COG1309	transcriptional regulator
HV292_RS16715	COG2233	PERMEase
HV292_RS16725	COG3729	General stress protein
HV292_RS16755	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS16770	COG0531	amino acid
HV292_RS16775	COG0174	glutamine synthetase
HV292_RS16780	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HV292_RS16785	COG1917	Cupin 2, conserved barrel domain protein
HV292_RS16785	COG1396	sequence-specific DNA binding
HV292_RS16790	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS16795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HV292_RS16800	COG0583	DNA-binding transcription factor activity
HV292_RS16805	COG0473	3-isopropylmalate dehydrogenase activity
HV292_RS16810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HV292_RS16815	COG4638	Rieske (2fe-2S)
HV292_RS16820	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS16825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV292_RS16880	COG3772	lysozyme
HV292_RS16910	COG0741	lytic transglycosylase activity
HV292_RS17055	COG0305	Participates in initiation and elongation during chromosome replication
HV292_RS17080	COG1396	sequence-specific DNA binding
HV292_RS17130	COG0670	Belongs to the BI1 family
HV292_RS17145	COG2207	Transcriptional regulator
HV292_RS17150	COG1881	PFAM PEBP family protein
HV292_RS17165	COG1832	CoA-binding protein
HV292_RS17175	COG0210	DNA helicase
HV292_RS17180	COG3304	Inner membrane component domain
HV292_RS17185	COG1289	transmembrane transporter activity
HV292_RS17190	COG3070	regulator of competence-specific genes
HV292_RS17210	COG1067	ATP-dependent peptidase activity
HV292_RS17220	COG3130	regulation of translation
HV292_RS17225	COG3009	Protein conserved in bacteria
HV292_RS17230	COG3008	intermembrane lipid transfer
HV292_RS17230	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV292_RS17235	COG2995	paraquat-inducible protein a
HV292_RS17240	COG0488	(ABC) transporter
HV292_RS17250	COG3217	Mosc domain protein beta barrel domain protein
HV292_RS17250	COG0633	Ferredoxin
HV292_RS17265	COG0431	NADPH-dependent FMN reductase
HV292_RS17270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV292_RS17275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV292_RS17280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV292_RS17290	COG0308	aminopeptidase N
HV292_RS17300	COG1473	amidohydrolase
HV292_RS17310	COG0814	amino acid
HV292_RS17330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV292_RS17335	COG1448	Aminotransferase
HV292_RS17340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV292_RS17345	COG3108	Peptidase M15
HV292_RS17350	COG2989	Protein conserved in bacteria
HV292_RS17360	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HV292_RS17370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HV292_RS17375	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV292_RS17380	COG3173	Aminoglycoside phosphotransferase
HV292_RS17395	COG3214	Protein conserved in bacteria
HV292_RS17410	COG0658	competence protein
HV292_RS17410	COG2333	competence protein COMEC
HV292_RS17420	COG0539	negative regulation of cytoplasmic translation
HV292_RS17440	COG2323	membrane
HV292_RS17445	COG1944	ATP diphosphatase activity
HV292_RS17450	COG2116	formate transmembrane transporter activity
HV292_RS17455	COG1882	Formate acetyltransferase
HV292_RS17460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV292_RS17465	COG0477	Major facilitator Superfamily
HV292_RS17470	COG3302	dmso reductase anchor subunit
HV292_RS17475	COG0437	4 iron, 4 sulfur cluster binding
HV292_RS17480	COG0243	molybdopterin cofactor binding
HV292_RS17490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HV292_RS17500	COG1178	ABC-type Fe3 transport system permease component
HV292_RS17500	COG1674	ftsk spoiiie
HV292_RS17510	COG0492	ferredoxin-NADP+ reductase activity
HV292_RS17515	COG4988	ABC transporter
HV292_RS17520	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HV292_RS17535	COG0542	response to heat
HV292_RS17545	COG1278	Cold shock
HV292_RS17555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV292_RS17560	COG3593	DNA synthesis involved in DNA repair
HV292_RS17570	COG2431	L-lysine efflux transmembrane transporter activity
HV292_RS17580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV292_RS17590	COG0028	Belongs to the TPP enzyme family
HV292_RS17595	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HV292_RS17600	COG0702	epimerase
HV292_RS17605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV292_RS17610	COG3023	N-Acetylmuramoyl-L-alanine amidase
HV292_RS17615	COG2203	Gaf domain
HV292_RS17615	COG5001	Diguanylate cyclase
HV292_RS17615	COG3706	GGDEF domain
HV292_RS17615	COG4251	negative regulation of phosphorylation
HV292_RS17625	COG1126	abc transporter atp-binding protein
HV292_RS17630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV292_RS17635	COG4215	(ABC) transporter
HV292_RS17640	COG4160	amino acid transport
HV292_RS17645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV292_RS17650	COG5002	protein histidine kinase activity
HV292_RS17655	COG0745	RESPONSE REGULATOR receiver
HV292_RS17660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HV292_RS17670	COG1177	transmembrane transport
HV292_RS17675	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV292_RS17680	COG3842	ATPase activity
HV292_RS17685	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV292_RS17700	COG0778	Nitroreductase
HV292_RS17725	COG3226	Transcriptional regulator
HV292_RS17730	COG0738	Major facilitator superfamily
HV292_RS17735	COG0561	phosphatase activity
HV292_RS17740	COG2814	Major facilitator Superfamily
HV292_RS17745	COG0671	phosphoesterase, PA-phosphatase related
HV292_RS17750	COG1349	DNA-binding transcription factor activity
HV292_RS17755	COG1686	Belongs to the peptidase S11 family
HV292_RS17770	COG0625	glutathione transferase activity
HV292_RS17775	COG2133	pyrroloquinoline quinone binding
HV292_RS17785	COG2223	nitrite transmembrane transporter activity
HV292_RS17805	COG0747	negative chemotaxis
HV292_RS17820	COG0303	'Molybdopterin
HV292_RS17825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV292_RS17830	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV292_RS17835	COG1882	Formate acetyltransferase
HV292_RS17840	COG0561	phosphatase activity
HV292_RS17850	COG1609	Transcriptional regulator
HV292_RS17855	COG2271	Major facilitator Superfamily
HV292_RS17865	COG0488	(ABC) transporter
HV292_RS17885	COG1376	ErfK ybiS ycfS ynhG family protein
HV292_RS17890	COG2188	Transcriptional regulator
HV292_RS17895	COG2723	6-phospho-beta-galactosidase activity
HV292_RS17900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV292_RS17915	COG2194	sulfuric ester hydrolase activity
HV292_RS17920	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HV292_RS17935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV292_RS17940	COG0765	amino acid transport
HV292_RS17945	COG1126	abc transporter atp-binding protein
HV292_RS17950	COG0668	transmembrane transport
HV292_RS17960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV292_RS17970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV292_RS17980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV292_RS17985	COG1199	ATP-dependent helicase activity
HV292_RS17990	COG0513	Belongs to the DEAD box helicase family
HV292_RS17995	COG3958	Transketolase
HV292_RS18000	COG3959	Transketolase, thiamine diphosphate binding domain
HV292_RS18005	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS18010	COG2271	Major facilitator Superfamily
HV292_RS18020	COG0583	DNA-binding transcription factor activity
HV292_RS18025	COG1309	transcriptional regulator
HV292_RS18030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV292_RS18035	COG1131	(ABC) transporter
HV292_RS18040	COG0842	Transport permease protein
HV292_RS18045	COG0842	Transport permease protein
HV292_RS18055	COG3568	Endonuclease Exonuclease Phosphatase
HV292_RS18060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV292_RS18065	COG0392	lysyltransferase activity
HV292_RS18070	COG0670	Belongs to the BI1 family
HV292_RS18075	COG0314	molybdopterin synthase activity
HV292_RS18080	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HV292_RS18090	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV292_RS18110	COG0745	RESPONSE REGULATOR receiver
HV292_RS18115	COG0642	Histidine kinase
HV292_RS18140	COG2226	methyltransferase
HV292_RS18155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HV292_RS18160	COG1881	PFAM PEBP family protein
HV292_RS18200	COG4677	pectinesterase activity
HV292_RS18210	COG0589	response to stress
HV292_RS18215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV292_RS18255	COG0789	Transcriptional regulator
HV292_RS18260	COG2200	EAL domain
HV292_RS18285	COG0561	phosphatase activity
HV292_RS18295	COG4149	molybdate abc transporter
HV292_RS18300	COG0725	ABC transporter, periplasmic molybdate-binding protein
HV292_RS18310	COG2005	Transcriptional regulator
HV292_RS18310	COG3585	molybdate ion transport
HV292_RS18315	COG1119	ATPase activity
HV292_RS18325	COG1085	galactose-1-phosphate uridylyltransferase
HV292_RS18335	COG2017	converts alpha-aldose to the beta-anomer
HV292_RS18345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV292_RS18360	COG3201	nicotinamide mononucleotide transporter
HV292_RS18365	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HV292_RS18415	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HV292_RS18420	COG2885	chlorophyll binding
HV292_RS18430	COG3064	Membrane
HV292_RS18435	COG0848	biopolymer transport protein
HV292_RS18440	COG0811	peptide transport
HV292_RS18445	COG0824	Thioesterase
HV292_RS18450	COG3790	cyd operon protein YbgE
HV292_RS18455	COG4890	Cyd operon protein YbgT
HV292_RS18460	COG1294	oxidase, subunit
HV292_RS18465	COG1271	oxidase subunit
HV292_RS18470	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV292_RS18480	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV292_RS18485	COG0567	Dehydrogenase, E1 component
HV292_RS18490	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV292_RS18495	COG1053	succinate dehydrogenase
HV292_RS18500	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HV292_RS18505	COG2009	succinate dehydrogenase
HV292_RS18540	COG1984	allophanate hydrolase subunit 2
HV292_RS18545	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HV292_RS18560	COG0415	Belongs to the DNA photolyase family
HV292_RS18590	COG2205	protein histidine kinase activity
HV292_RS18595	COG0745	RESPONSE REGULATOR receiver
HV292_RS18605	COG0033	Phosphoglucomutase
HV292_RS18615	COG0596	Alpha beta hydrolase
HV292_RS18630	COG0735	belongs to the Fur family
HV292_RS18670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV292_RS18675	COG1846	Transcriptional regulator
HV292_RS18675	COG1940	carbohydrate kinase activity
HV292_RS18680	COG0647	UMP catabolic process
HV292_RS18685	COG0367	asparagine synthase
HV292_RS18725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV292_RS18735	COG1702	phosphate starvation-inducible protein PhoH
HV292_RS18760	COG0765	amino acid transport
HV292_RS18765	COG0765	amino acid transport
HV292_RS18770	COG1126	abc transporter atp-binding protein
HV292_RS18785	COG2888	peptidyl-tyrosine sulfation
HV292_RS18800	COG1466	dna polymerase III delta subunit
HV292_RS18815	COG0799	negative regulation of ribosome biogenesis
HV292_RS18825	COG0768	penicillin binding
HV292_RS18830	COG0772	Belongs to the SEDS family
HV292_RS18835	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV292_RS18840	COG1686	Belongs to the peptidase S11 family
HV292_RS18855	COG0583	DNA-binding transcription factor activity
HV292_RS18870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV292_RS18890	COG3069	C4-dicarboxylate transmembrane transporter activity
HV292_RS18895	COG3719	Belongs to the RNase T2 family
HV292_RS18900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV292_RS18920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HV292_RS18925	COG0583	DNA-binding transcription factor activity
HV292_RS18930	COG3969	phosphoadenosine phosphosulfate
HV292_RS18935	COG1475	DNA binding
HV292_RS18940	COG0436	Aminotransferase
HV292_RS18965	COG1129	ABC transporter
HV292_RS18970	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS18975	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS18985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV292_RS19000	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HV292_RS19010	COG0402	S-adenosylhomocysteine deaminase activity
HV292_RS19020	COG0483	inositol monophosphate 1-phosphatase activity
HV292_RS19055	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS19060	COG1129	ABC transporter
HV292_RS19065	COG0371	Dehydrogenase
HV292_RS19070	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS19085	COG2879	small protein
HV292_RS19090	COG1966	Carbon starvation protein
HV292_RS19100	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS19105	COG3433	isochorismatase activity
HV292_RS19105	COG1535	isochorismatase
HV292_RS19110	COG1021	2,3-dihydroxybenzoate-AMP ligase
HV292_RS19115	COG1169	isochorismate synthase
HV292_RS19120	COG4592	Periplasmic binding protein
HV292_RS19130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV292_RS19135	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV292_RS19140	COG1120	ATPase activity
HV292_RS19145	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HV292_RS19145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HV292_RS19150	COG3251	PFAM MbtH domain protein
HV292_RS19155	COG2382	esterase
HV292_RS19165	COG2977	Belongs to the P-Pant transferase superfamily
HV292_RS19170	COG3958	Transketolase
HV292_RS19175	COG3959	Transketolase, thiamine diphosphate binding domain
HV292_RS19180	COG2390	Transcriptional regulator
HV292_RS19185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HV292_RS19190	COG1879	ABC-type sugar transport system periplasmic component
HV292_RS19200	COG1129	ABC transporter
HV292_RS19205	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS19215	COG1028	Short-chain dehydrogenase reductase Sdr
HV292_RS19225	COG0583	DNA-binding transcription factor activity
HV292_RS19230	COG0668	transmembrane transport
HV292_RS19240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HV292_RS19265	COG0747	negative chemotaxis
HV292_RS19270	COG0601	transmembrane transport
HV292_RS19275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV292_RS19280	COG0444	Belongs to the ABC transporter superfamily
HV292_RS19285	COG4608	Belongs to the ABC transporter superfamily
HV292_RS19295	COG4221	oxidoreductase activity
HV292_RS19305	COG4215	(ABC) transporter
HV292_RS19310	COG0765	amino acid transport
HV292_RS19315	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HV292_RS19330	COG0697	spore germination
HV292_RS19345	COG4608	Belongs to the ABC transporter superfamily
HV292_RS19350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV292_RS19360	COG4166	transmembrane transport
HV292_RS19370	COG3698	Phosphodiester glycosidase
HV292_RS19410	COG2315	Protein conserved in bacteria
HV292_RS19415	COG0778	Nitroreductase
HV292_RS19440	COG0477	Major facilitator Superfamily
HV292_RS19445	COG0668	transmembrane transport
HV292_RS19460	COG0673	inositol 2-dehydrogenase activity
HV292_RS19470	COG2211	Major facilitator Superfamily
HV292_RS19475	COG1113	amino acid transport
HV292_RS19490	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS19495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HV292_RS19505	COG0531	amino acid
HV292_RS19550	COG0667	Aldo Keto reductase
HV292_RS19555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV292_RS19560	COG1473	amidohydrolase
HV292_RS19590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV292_RS19595	COG1120	ATPase activity
HV292_RS19600	COG1566	PFAM secretion protein HlyD family protein
HV292_RS19645	COG4211	Belongs to the binding-protein-dependent transport system permease family
HV292_RS19650	COG1129	ABC transporter
HV292_RS19665	COG0673	inositol 2-dehydrogenase activity
HV292_RS19695	COG3104	oligopeptide transport
HV292_RS19700	COG1982	Orn Lys Arg decarboxylase major
HV292_RS19705	COG0531	amino acid
HV292_RS19710	COG3710	Transcriptional regulator
HV292_RS19720	COG1560	Kdo2-lipid A biosynthetic process
HV292_RS19735	COG3188	usher protein
HV292_RS19740	COG3121	Chaperone
HV292_RS19745	COG3539	Fimbrial protein
HV292_RS19875	COG0582	viral genome integration into host DNA
HV292_RS19960	COG0739	heme binding
HV292_RS19960	COG0741	lytic transglycosylase activity
HV292_RS19960	COG1196	nuclear chromosome segregation
HV292_RS19970	COG3646	Phage regulatory protein
HV292_RS20035	COG5410	chromosome segregation
HV292_RS20210	COG3723	Recombinational DNA repair protein, rece pathway
HV292_RS20270	COG2501	S4 domain
HV292_RS20280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HV292_RS20295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HV292_RS20300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HV292_RS20320	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HV292_RS20325	COG4181	ATPase activity
HV292_RS20330	COG2755	lipolytic protein G-D-S-L family
HV292_RS20335	COG0300	oxidoreductase activity
HV292_RS20340	COG3118	belongs to the thioredoxin family
HV292_RS20345	COG0390	transport system, permease component
HV292_RS20350	COG4619	ABC transporter
HV292_RS20355	COG0330	HflC and HflK could
HV292_RS20360	COG1585	Membrane protein implicated in regulation of membrane protease activity
HV292_RS20375	COG3735	TraB family
HV292_RS20380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV292_RS20390	COG2223	nitrite transmembrane transporter activity
HV292_RS20395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HV292_RS20395	COG4651	solute:proton antiporter activity
HV292_RS20400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV292_RS20440	COG2832	Protein of unknown function (DUF454)
HV292_RS20445	COG3923	Primosomal replication protein n
HV292_RS20460	COG1196	nuclear chromosome segregation
HV292_RS20460	COG3264	Mechanosensitive ion channel
HV292_RS20465	COG1309	transcriptional regulator
HV292_RS20470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV292_RS20475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV292_RS20490	COG0110	maltose O-acetyltransferase activity
HV292_RS20540	COG1874	Beta-galactosidase
HV292_RS20545	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HV292_RS20550	COG3833	ABC-type maltose transport systems, permease component
HV292_RS20555	COG1175	transmembrane transport
HV292_RS20560	COG2182	Extracellular solute-binding protein
HV292_RS20570	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV292_RS20585	COG2364	Membrane
HV292_RS20615	COG3695	enzyme binding
HV292_RS20620	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HV292_RS20625	COG1946	Acyl-CoA thioesterase
HV292_RS20630	COG0004	ammonium transporteR
HV292_RS20635	COG0347	Belongs to the P(II) protein family
HV292_RS20640	COG1132	(ABC) transporter
HV292_RS20645	COG1132	(ABC) transporter
HV292_RS20650	COG1522	sequence-specific DNA binding
HV292_RS20665	COG4533	DNA binding
HV292_RS20675	COG0824	Thioesterase
HV292_RS20680	COG1555	photosystem II stabilization
HV292_RS20685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV292_RS20690	COG0776	regulation of translation
HV292_RS20695	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HV292_RS20715	COG0271	Belongs to the BolA IbaG family
HV292_RS20720	COG3056	Lipoprotein
HV292_RS20725	COG2223	nitrite transmembrane transporter activity
HV292_RS20730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HV292_RS20735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HV292_RS20740	COG1845	cytochrome c oxidase, subunit III
HV292_RS20745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HV292_RS20760	COG1414	Transcriptional regulator
HV292_RS20765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV292_RS20770	COG1053	succinate dehydrogenase
HV292_RS20795	COG0673	inositol 2-dehydrogenase activity
HV292_RS20800	COG2814	Major facilitator Superfamily
HV292_RS20810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HV292_RS20815	COG0693	protein deglycase activity
HV292_RS20835	COG0142	geranyltranstransferase activity
HV292_RS20845	COG0667	Aldo Keto reductase
HV292_RS20850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HV292_RS20870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV292_RS20870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV292_RS20880	COG4238	major outer membrane lipoprotein
HV292_RS20900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV292_RS20905	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV292_RS20910	COG1862	Preprotein translocase
HV292_RS20935	COG0450	alkyl hydroperoxide reductase
HV292_RS20945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV292_RS20960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV292_RS20970	COG1228	amidohydrolase
HV292_RS20980	COG1335	isochorismatase
HV292_RS20985	COG0583	DNA-binding transcription factor activity
HV292_RS20990	COG0366	Alpha amylase catalytic
HV292_RS21015	COG0420	3'-5' exonuclease activity
HV292_RS21020	COG0419	ATPase involved in DNA repair
HV292_RS21025	COG1940	carbohydrate kinase activity
HV292_RS21040	COG4126	flavin adenine dinucleotide binding
HV292_RS21050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HV292_RS21055	COG3416	Protein conserved in bacteria
HV292_RS21065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HV292_RS21075	COG1785	Belongs to the alkaline phosphatase family
HV292_RS21125	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HV292_RS21130	COG1335	isochorismatase
HV292_RS21135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HV292_RS21140	COG0113	porphobilinogen synthase activity
HV292_RS21150	COG2175	clavaminate synthase activity
HV292_RS21155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV292_RS21160	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HV292_RS21165	COG4521	taurine ABC transporter
HV292_RS21175	COG2040	homocysteine
HV292_RS21180	COG0833	amino acid
HV292_RS21195	COG4303	Ethanolamine ammonia lyase large subunit
HV292_RS21200	COG4302	ethanolamine ammonia-lyase activity
HV292_RS21240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV292_RS21245	COG1126	abc transporter atp-binding protein
HV292_RS21250	COG0765	amino acid transport
HV292_RS21255	COG0765	amino acid transport
HV292_RS21270	COG3188	usher protein
HV292_RS21295	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HV292_RS21305	COG3639	organic phosphonate transmembrane transporter activity
HV292_RS21325	COG0791	NLP P60 protein
HV292_RS21350	COG0582	viral genome integration into host DNA
HV292_RS21370	COG2814	Major facilitator Superfamily
HV292_RS21380	COG3039	Transposase
HV292_RS21390	COG1263	PTS System
HV292_RS21390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV292_RS21390	COG2190	(PTS) system
HV292_RS21400	COG0673	inositol 2-dehydrogenase activity
HV292_RS21405	COG0673	inositol 2-dehydrogenase activity
HV292_RS21410	COG0583	DNA-binding transcription factor activity
HV292_RS21420	COG3436	PFAM IS66 Orf2 family protein
HV292_RS21425	COG4372	Transposase
HV292_RS21435	COG1408	metallophosphoesterase
HV292_RS21460	COG4221	oxidoreductase activity
HV292_RS21490	COG3344	reverse transcriptase
HV292_RS21520	COG2200	EAL domain
HV292_RS21535	COG3039	Transposase
HV292_RS21550	COG3121	Chaperone
HV292_RS21575	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HV292_RS21590	COG0579	oxidoreductase
HV292_RS21595	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS21600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV292_RS21605	COG1113	amino acid transport
HV292_RS21610	COG1802	Transcriptional regulator
HV292_RS21630	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV292_RS21635	COG0454	-acetyltransferase
HV292_RS21650	COG2991	Protein conserved in bacteria
HV292_RS21665	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV292_RS21670	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HV292_RS21685	COG3034	peptidoglycan biosynthetic process
HV292_RS21690	COG0121	glutamine amidotransferase
HV292_RS21700	COG1960	acyl-CoA dehydrogenase activity
HV292_RS21705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV292_RS21715	COG0583	DNA-binding transcription factor activity
HV292_RS21725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV292_RS21735	COG2226	methyltransferase
HV292_RS21745	COG1388	LysM domain
HV292_RS21745	COG0741	lytic transglycosylase activity
HV292_RS21750	COG2226	methyltransferase
HV292_RS21760	COG2814	Major facilitator Superfamily
HV292_RS21765	COG0583	DNA-binding transcription factor activity
HV292_RS21770	COG0656	L-ascorbic acid biosynthetic process
HV292_RS21805	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HV292_RS21815	COG2011	ABC-type metal ion transport system permease component
HV292_RS21820	COG1464	Belongs to the NlpA lipoprotein family
HV292_RS21830	COG1720	tRNA m6t6A37 methyltransferase activity
HV292_RS21840	COG0791	NLP P60 protein
HV292_RS21845	COG3015	lipoprotein NlpE involved in copper resistance
HV292_RS21850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HV292_RS21865	COG4568	rho-dependent transcription termination
HV292_RS21875	COG0346	lactoylglutathione lyase activity
HV292_RS21890	COG0587	DNA-directed DNA polymerase activity
HV292_RS21920	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HV292_RS21930	COG0750	zinc metalloprotease
HV292_RS21935	COG0575	Belongs to the CDS family
HV292_RS21970	COG0024	Methionine aminopeptidase
HV292_RS21975	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HV292_RS21990	COG3835	regulator
HV292_RS21995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV292_RS22015	COG2860	membrane
HV292_RS22035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV292_RS22040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV292_RS22045	COG1120	ATPase activity
HV292_RS22055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HV292_RS22145	COG1643	Atp-dependent helicase
HV292_RS22150	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HV292_RS22170	COG0617	tRNA 3'-terminal CCA addition
HV292_RS22175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HV292_RS22195	COG0726	polysaccharide deacetylase
HV292_RS22200	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV292_RS22205	COG0842	Transport permease protein
HV292_RS22210	COG1131	(ABC) transporter
HV292_RS22215	COG0288	reversible hydration of carbon dioxide
HV292_RS22230	COG4993	Dehydrogenase
HV292_RS22235	COG2132	Multicopper oxidase
HV292_RS22280	COG3064	Membrane
HV292_RS22295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV292_RS22300	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV292_RS22305	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HV292_RS22310	COG2186	Transcriptional regulator
HV292_RS22315	COG1113	amino acid transport
HV292_RS22320	COG2211	Major facilitator Superfamily
HV292_RS22325	COG3940	Belongs to the glycosyl hydrolase 43 family
HV292_RS22330	COG3725	Membrane protein required for beta-lactamase induction
HV292_RS22335	COG3023	N-Acetylmuramoyl-L-alanine amidase
HV292_RS22345	COG4969	Belongs to the N-Me-Phe pilin family
HV292_RS22350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV292_RS22355	COG1459	type II secretion system
HV292_RS22380	COG0494	nUDIX hydrolase
HV292_RS22400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HV292_RS22405	COG0849	cell division
HV292_RS22430	COG0772	Belongs to the SEDS family
HV292_RS22445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HV292_RS22450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HV292_RS22455	COG0768	penicillin binding
HV292_RS22475	COG1609	Transcriptional regulator
HV292_RS22485	COG0028	Belongs to the TPP enzyme family
HV292_RS22530	COG0738	Major facilitator superfamily
HV292_RS22540	COG0583	DNA-binding transcription factor activity
HV292_RS22545	COG2271	Major facilitator Superfamily
HV292_RS22550	COG2814	Major facilitator Superfamily
HV292_RS22570	COG1178	ABC-type Fe3 transport system permease component
HV292_RS22580	COG0586	Pfam SNARE associated Golgi protein
HV292_RS22600	COG0235	Class ii aldolase
HV292_RS22605	COG0417	DNA replication proofreading
HV292_RS22615	COG0564	pseudouridine synthase activity
HV292_RS22625	COG3493	citrate carrier protein
HV292_RS22640	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HV292_RS22645	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HV292_RS22655	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HV292_RS22700	COG0505	Belongs to the CarA family
HV292_RS22765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HV292_RS22790	COG1047	Peptidyl-prolyl cis-trans
HV292_RS22805	COG0196	riboflavin kinase activity
HV292_RS22840	COG4735	regulation of single-species biofilm formation
HV292_RS22845	COG1584	GPR1 FUN34 yaaH family protein
HV292_RS22850	COG0477	Major facilitator Superfamily
HV292_RS22855	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV292_RS22860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HV292_RS22865	COG1115	amino acid carrier protein
HV292_RS22875	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HV292_RS22885	COG0527	aspartate kinase activity
HV292_RS22885	COG0460	homoserine dehydrogenase
HV292_RS22895	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HV292_RS22905	COG0745	RESPONSE REGULATOR receiver
HV292_RS22910	COG4452	Inner membrane protein CreD
HV292_RS22915	COG2205	protein histidine kinase activity
HV292_RS22920	COG0745	RESPONSE REGULATOR receiver
HV292_RS22925	COG3045	CreA protein
HV292_RS22930	COG3708	Transcriptional regulator
HV292_RS22930	COG2207	Transcriptional regulator
HV292_RS22950	COG0741	lytic transglycosylase activity
HV292_RS22955	COG0488	(ABC) transporter
HV292_RS22965	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HV292_RS22970	COG0560	Phosphoserine phosphatase
HV292_RS22975	COG3726	membrane protein affecting hemolysin expression
HV292_RS23005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV292_RS23010	COG0084	hydrolase, TatD family'
HV292_RS23015	COG4667	esterase of the alpha-beta hydrolase superfamily
HV292_RS23025	COG2823	Periplasmic or secreted lipoprotein
HV292_RS23035	COG1011	Hydrolase
HV292_RS23040	COG0456	acetyltransferase
HV292_RS23045	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HV292_RS23080	COG3706	GGDEF domain
HV292_RS23085	COG4114	ferric iron reductase
HV292_RS23090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV292_RS23095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV292_RS23100	COG2197	response regulator
HV292_RS23105	COG2197	response regulator
HV292_RS23125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV292_RS23235	COG4373	Mu-like prophage FluMu protein gp28
HV292_RS23260	COG0741	lytic transglycosylase activity
HV292_RS23305	COG3409	Peptidoglycan-binding domain 1 protein
HV292_RS23305	COG3267	Type II secretory pathway component ExeA
HV292_RS23380	COG1484	DNA-dependent DNA replication
HV292_RS23395	COG5464	transposase or invertase
HV292_RS23405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HV292_RS23410	COG3716	PTS system mannose fructose sorbose family IID component
HV292_RS23415	COG3715	PTS system
HV292_RS23430	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HV292_RS23430	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV292_RS23435	COG0456	acetyltransferase
HV292_RS23435	COG1214	PFAM Peptidase M22, glycoprotease
HV292_RS23445	COG1737	Transcriptional regulator
HV292_RS23450	COG0800	Aldolase
HV292_RS23455	COG3734	2-keto-3-deoxy-galactonokinase
HV292_RS23470	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HV292_RS23495	COG1846	Transcriptional regulator
HV292_RS23505	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV292_RS23515	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS23520	COG3384	dioxygenase
HV292_RS23530	COG3971	2-oxopent-4-enoate hydratase activity
HV292_RS23550	COG2368	4-hydroxyphenylacetate
HV292_RS23555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV292_RS23570	COG1966	Carbon starvation protein
HV292_RS23575	COG2879	small protein
HV292_RS23580	COG0523	cobalamin synthesis protein
HV292_RS23590	COG1012	belongs to the aldehyde dehydrogenase family
HV292_RS23595	COG5464	transposase or invertase
HV292_RS23600	COG2207	Transcriptional regulator
HV292_RS23600	COG1917	Cupin 2, conserved barrel domain protein
HV292_RS23610	COG2733	membrane
HV292_RS23625	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HV292_RS23630	COG1924	4 iron, 4 sulfur cluster binding
HV292_RS23655	COG1566	PFAM secretion protein HlyD family protein
HV292_RS23665	COG5457	Domain of unknown function (DUF1127)
HV292_RS23670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV292_RS23685	COG0583	DNA-binding transcription factor activity
HV292_RS23690	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV292_RS23700	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS23705	COG1129	ABC transporter
HV292_RS23710	COG1879	ABC-type sugar transport system periplasmic component
HV292_RS23720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV292_RS23725	COG0842	Transport permease protein
HV292_RS23725	COG1129	ABC transporter
HV292_RS23730	COG0842	Transport permease protein
HV292_RS23760	COG2850	peptidyl-arginine hydroxylation
HV292_RS23775	COG5002	protein histidine kinase activity
HV292_RS23780	COG0745	RESPONSE REGULATOR receiver
HV292_RS23785	COG1538	Outer membrane efflux protein
HV292_RS23790	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV292_RS23795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV292_RS23800	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV292_RS23810	COG3040	lipid binding
HV292_RS23815	COG0789	Transcriptional regulator
HV292_RS23825	COG0300	oxidoreductase activity
HV292_RS23840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV292_RS23860	COG3272	Protein of unknown function (DUF1722)
HV292_RS23865	COG4580	involved in the transport of maltose and maltodextrins
HV292_RS23870	COG2115	Belongs to the xylose isomerase family
HV292_RS23875	COG2211	Major facilitator Superfamily
HV292_RS23880	COG3507	Belongs to the glycosyl hydrolase 43 family
HV292_RS23890	COG0584	glycerophosphoryl diester phosphodiesterase
HV292_RS23900	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV292_RS23925	COG3039	Transposase
HV292_RS23960	COG1216	Glycosyl transferase, family 2
HV292_RS24015	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HV292_RS24020	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HV292_RS24045	COG2003	Belongs to the UPF0758 family
HV292_RS24060	COG3596	GTP binding
HV292_RS24080	COG0288	reversible hydration of carbon dioxide
HV292_RS24085	COG0659	secondary active sulfate transmembrane transporter activity
HV292_RS24090	COG1064	alcohol dehydrogenase
HV292_RS24095	COG1175	transmembrane transport
HV292_RS24100	COG0395	ABC-type sugar transport system, permease component
HV292_RS24105	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HV292_RS24110	COG3842	ATPase activity
HV292_RS24125	COG1082	Xylose isomerase domain protein TIM barrel
HV292_RS24135	COG3962	Belongs to the TPP enzyme family
HV292_RS24140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV292_RS24145	COG1737	Transcriptional regulator
HV292_RS24145	COG0837	glucose binding
HV292_RS24155	COG3718	enzyme involved in inositol metabolism
HV292_RS24170	COG0433	COG0433 Predicted ATPase
HV292_RS24175	COG0795	lipopolysaccharide-transporting ATPase activity
HV292_RS24180	COG0795	lipopolysaccharide-transporting ATPase activity
HV292_RS24190	COG2927	DNA polymerase III (CHI subunit)
HV292_RS24195	COG0525	valine-tRNA ligase activity
HV292_RS24220	COG2731	YhcH YjgK YiaL family protein
HV292_RS24255	COG1263	PTS System
HV292_RS24255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV292_RS24260	COG0366	Alpha amylase catalytic
HV292_RS24265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV292_RS24270	COG1486	melibiose metabolic process
HV292_RS24295	COG0602	queuosine metabolic process
HV292_RS24300	COG2026	Addiction module toxin, RelE StbE family
HV292_RS24305	COG3077	Addiction module antitoxin, RelB DinJ family
HV292_RS24310	COG3711	transcriptional antiterminator
HV292_RS24310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV292_RS24315	COG2706	6-phosphogluconolactonase activity
HV292_RS24330	COG3964	amidohydrolase
HV292_RS24365	COG0312	modulator of DNA gyrase
HV292_RS24390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HV292_RS24400	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS24405	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS24410	COG1129	ABC transporter
HV292_RS24415	COG1879	ABC-type sugar transport system periplasmic component
HV292_RS24435	COG2105	PFAM AIG2 family protein
HV292_RS24440	COG2911	Protein conserved in bacteria
HV292_RS24445	COG0729	surface antigen
HV292_RS24455	COG1253	flavin adenine dinucleotide binding
HV292_RS24470	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HV292_RS24485	COG1733	regulation of RNA biosynthetic process
HV292_RS24490	COG0702	epimerase
HV292_RS24500	COG0697	spore germination
HV292_RS24510	COG1113	amino acid transport
HV292_RS24515	COG0545	Peptidyl-prolyl cis-trans isomerase
HV292_RS24520	COG3061	Opacity-associated protein A
HV292_RS24530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HV292_RS24535	COG2965	DNA replication, synthesis of RNA primer
HV292_RS24595	COG1073	alpha beta
HV292_RS24600	COG3650	response to hydrogen peroxide
HV292_RS24610	COG1960	acyl-CoA dehydrogenase activity
HV292_RS24615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV292_RS24620	COG0557	exoribonuclease II activity
HV292_RS24635	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HV292_RS24645	COG0330	HflC and HflK could
HV292_RS24650	COG0330	HflC and HflK could
HV292_RS24655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HV292_RS24675	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV292_RS24680	COG0802	atpase or kinase
HV292_RS24685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HV292_RS24685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HV292_RS24690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HV292_RS24710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV292_RS24730	COG1511	domain protein
HV292_RS24730	COG3264	Mechanosensitive ion channel
HV292_RS24745	COG1053	succinate dehydrogenase
HV292_RS24750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV292_RS24770	COG2076	Multidrug Resistance protein
HV292_RS24775	COG5510	response to toxic substance
HV292_RS24790	COG1509	lysine 2,3-aminomutase activity
HV292_RS24795	COG0745	RESPONSE REGULATOR receiver
HV292_RS24870	COG0531	amino acid
HV292_RS24875	COG3030	protein affecting phage T7 exclusion by the F plasmid
HV292_RS24880	COG1027	Aspartate ammonia-lyase
HV292_RS24885	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV292_RS24900	COG1309	transcriptional regulator
HV292_RS24930	COG0457	Tetratricopeptide repeat
HV292_RS24935	COG0726	polysaccharide deacetylase
HV292_RS24935	COG1649	PFAM Uncharacterised BCR, COG1649
HV292_RS24940	COG1215	transferase activity, transferring glycosyl groups
HV292_RS24955	COG0861	Integral membrane protein TerC family
HV292_RS24995	COG1486	melibiose metabolic process
HV292_RS25000	COG2169	Transcriptional regulator
HV292_RS25010	COG2824	Alkylphosphonate utilization operon protein PhnA
HV292_RS25015	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HV292_RS25020	COG2188	Transcriptional regulator
HV292_RS25025	COG3624	Phosphonate C-P lyase system protein PhnG
HV292_RS25030	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HV292_RS25035	COG3626	phosphonate metabolism
HV292_RS25040	COG3627	carbon phosphorus lyase activity
HV292_RS25045	COG4107	phosphonate C-P lyase system protein PhnK
HV292_RS25050	COG4778	phosphonate C-P lyase system protein PhnL
HV292_RS25055	COG3454	Phosphonate metabolism
HV292_RS25065	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HV292_RS25075	COG0784	Response regulator, receiver
HV292_RS25075	COG4191	Histidine kinase
HV292_RS25080	COG1129	ABC transporter
HV292_RS25085	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS25120	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HV292_RS25125	COG1301	dicarboxylic acid transport
HV292_RS25135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HV292_RS25140	COG3162	membrane
HV292_RS25170	COG3539	Fimbrial protein
HV292_RS25175	COG1346	cytolysis
HV292_RS25180	COG1380	Effector of murein hydrolase LrgA
HV292_RS25185	COG0583	DNA-binding transcription factor activity
HV292_RS25190	COG0025	NhaP-type Na H and K H
HV292_RS25195	COG2252	PERMEase
HV292_RS25200	COG0625	glutathione transferase activity
HV292_RS25205	COG0789	Transcriptional regulator
HV292_RS25215	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV292_RS25245	COG1234	tRNA 3'-trailer cleavage
HV292_RS25250	COG1609	Transcriptional regulator
HV292_RS25255	COG0483	inositol monophosphate 1-phosphatase activity
HV292_RS25265	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV292_RS25285	COG4771	TonB-dependent receptor
HV292_RS25290	COG0741	lytic transglycosylase activity
HV292_RS25305	COG2315	Protein conserved in bacteria
HV292_RS25310	COG0432	Pfam Uncharacterised protein family UPF0047
HV292_RS25325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HV292_RS25330	COG0305	Participates in initiation and elongation during chromosome replication
HV292_RS25345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV292_RS25355	COG0735	belongs to the Fur family
HV292_RS25360	COG3237	CsbD-like
HV292_RS25370	COG0534	Mate efflux family protein
HV292_RS25380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HV292_RS25450	COG0251	oxidation-reduction process
HV292_RS25460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HV292_RS25470	COG0527	aspartate kinase activity
HV292_RS25525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HV292_RS25555	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HV292_RS25565	COG0456	acetyltransferase
HV292_RS25595	COG0151	Belongs to the GarS family
HV292_RS25605	COG4191	Histidine kinase
HV292_RS25610	COG3678	ATP-independent chaperone mediated protein folding
HV292_RS25645	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HV292_RS25660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV292_RS25665	COG2104	thiamine diphosphate biosynthetic process
HV292_RS25680	COG3706	GGDEF domain
HV292_RS25690	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV292_RS25695	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV292_RS25730	COG0250	Participates in transcription elongation, termination and antitermination
HV292_RS25805	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HV292_RS25815	COG1739	Uncharacterized protein family UPF0029
HV292_RS25855	COG0805	protein transport
HV292_RS25875	COG3165	ubiquinone biosynthetic process from chorismate
HV292_RS25905	COG0583	DNA-binding transcription factor activity
HV292_RS25910	COG0697	spore germination
HV292_RS25915	COG0561	phosphatase activity
HV292_RS25920	COG2267	carboxylic ester hydrolase activity
HV292_RS25925	COG1280	lysine exporter protein (LysE YggA)
HV292_RS25935	COG1280	lysine exporter protein (LysE YggA)
HV292_RS25965	COG0210	DNA helicase
HV292_RS25970	COG1011	Hydrolase
HV292_RS26000	COG3072	Adenylate cyclase
HV292_RS26015	COG2959	enzyme of heme biosynthesis
HV292_RS26020	COG3071	HemY protein
HV292_RS26065	COG2244	polysaccharide biosynthetic process
HV292_RS26070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HV292_RS26075	COG0456	acetyltransferase
HV292_RS26080	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HV292_RS26085	COG1088	dTDP-glucose 4,6-dehydratase activity
HV292_RS26090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HV292_RS26095	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HV292_RS26105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HV292_RS26110	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HV292_RS26115	COG3118	belongs to the thioredoxin family
HV292_RS26140	COG1811	Na channel or pump
HV292_RS26150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV292_RS26155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV292_RS26165	COG0583	DNA-binding transcription factor activity
HV292_RS26170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV292_RS26185	COG3978	acetolactate synthase activity
HV292_RS26205	COG3085	chromosome segregation
HV292_RS26280	COG0583	DNA-binding transcription factor activity
HV292_RS26295	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HV292_RS26310	COG3443	Belongs to the bacterial solute-binding protein 9 family
HV292_RS26315	COG2207	Transcriptional regulator
HV292_RS26325	COG0371	Dehydrogenase
HV292_RS26330	COG0697	spore germination
HV292_RS26340	COG0583	DNA-binding transcription factor activity
HV292_RS26350	COG0737	Belongs to the 5'-nucleotidase family
HV292_RS26360	COG0460	homoserine dehydrogenase
HV292_RS26360	COG0527	aspartate kinase activity
HV292_RS26365	COG0626	cystathionine gamma-synthase activity
HV292_RS26380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HV292_RS26385	COG1609	Transcriptional regulator
HV292_RS26390	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV292_RS26405	COG1575	Belongs to the MenA family. Type 1 subfamily
HV292_RS26425	COG3678	ATP-independent chaperone mediated protein folding
HV292_RS26430	COG0745	RESPONSE REGULATOR receiver
HV292_RS26435	COG2205	protein histidine kinase activity
HV292_RS26440	COG2258	MOSC domain
HV292_RS26445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HV292_RS26485	COG1129	ABC transporter
HV292_RS26490	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS26495	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS26500	COG1454	alcohol dehydrogenase
HV292_RS26510	COG2211	Major facilitator Superfamily
HV292_RS26570	COG0205	6-phosphofructokinase activity
HV292_RS26590	COG0437	4 iron, 4 sulfur cluster binding
HV292_RS26595	COG2864	formate dehydrogenase
HV292_RS26610	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV292_RS26620	COG0456	acetyltransferase
HV292_RS26635	COG1011	Hydrolase
HV292_RS26650	COG3852	Histidine kinase
HV292_RS26665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV292_RS26705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HV292_RS26710	COG3084	Protein conserved in bacteria
HV292_RS26720	COG1763	Mo-molybdopterin cofactor biosynthetic process
HV292_RS26745	COG2186	Transcriptional regulator
HV292_RS26750	COG0477	Major facilitator Superfamily
HV292_RS26755	COG1609	Transcriptional regulator
HV292_RS26760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV292_RS26770	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV292_RS26775	COG1129	ABC transporter
HV292_RS26805	COG1522	sequence-specific DNA binding
HV292_RS26810	COG0716	FMN binding
HV292_RS26825	COG3312	ion transport
HV292_RS26875	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HV292_RS26880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HV292_RS26885	COG0573	inorganic phosphate transmembrane transporter activity
HV292_RS26890	COG0581	inorganic phosphate transmembrane transporter activity
HV292_RS26895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HV292_RS26900	COG0704	Plays a role in the regulation of phosphate uptake
HV292_RS26910	COG2382	esterase
HV292_RS26915	COG0363	glucosamine-6-phosphate deaminase activity
HV292_RS26920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV292_RS26925	COG2252	PERMEase
HV292_RS26930	COG0431	NADPH-dependent FMN reductase
HV292_RS26935	COG2091	lysine biosynthetic process via aminoadipic acid
HV292_RS26965	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HV292_RS27020	COG2197	response regulator
HV292_RS27065	COG3039	Transposase
HV292_RS27220	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV292_RS27250	COG0739	heme binding
HV292_RS27260	COG2132	Multicopper oxidase
HV292_RS27265	COG3667	copper resistance
HV292_RS27270	COG2372	response to copper ion
HV292_RS27275	COG1276	copper resistance
HV292_RS27280	COG0745	RESPONSE REGULATOR receiver
HV292_RS27285	COG2205	protein histidine kinase activity
HV292_RS27310	COG3436	PFAM IS66 Orf2 family protein
HV292_RS27315	COG4372	Transposase
HV292_RS27370	COG2801	Transposase and inactivated derivatives
HV292_RS27380	COG2801	Transposase and inactivated derivatives
HV292_RS27390	COG2801	Transposase and inactivated derivatives
HV292_RS27400	COG3344	reverse transcriptase
HV292_RS27465	COG0071	Belongs to the small heat shock protein (HSP20) family
HV292_RS27470	COG0542	response to heat
HV292_RS27525	COG0501	Belongs to the peptidase M48B family
HV292_RS27530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV292_RS27560	COG3436	PFAM IS66 Orf2 family protein
HV292_RS27565	COG4372	Transposase
HV292_RS27595	COG3409	Peptidoglycan-binding domain 1 protein
HV292_RS27595	COG3429	Glucose-6-phosphate dehydrogenase subunit
HV292_RS27605	COG3436	PFAM IS66 Orf2 family protein
HV292_RS27625	COG4172	Belongs to the ABC transporter superfamily
HV292_RS27640	COG0601	transmembrane transport
HV292_RS27645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV292_RS27680	COG1595	DNA-templated transcription, initiation
HV292_RS27685	COG3712	iron ion homeostasis
HV292_RS27690	COG4772	TonB-dependent receptor
HV292_RS27695	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HV292_RS27700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV292_RS27705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV292_RS27710	COG1120	ATPase activity
HV292_RS27715	COG3436	PFAM IS66 Orf2 family protein
HV292_RS27745	COG1609	Transcriptional regulator
HV292_RS27755	COG2223	nitrite transmembrane transporter activity
HV292_RS28045	COG5499	transcription regulator containing HTH domain
HV292_RS28100	COG1475	DNA binding
HV292_RS28195	COG3344	reverse transcriptase
HV292_RS28200	COG3344	reverse transcriptase
HV292_RS28255	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HV292_RS28265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HV292_RS28280	COG1278	Cold shock
HV292_RS28325	COG3344	reverse transcriptase
HV292_RS28345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV292_RS28355	COG1702	phosphate starvation-inducible protein PhoH
HV292_RS28480	COG3941	tape measure
HV292_RS28570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HV292_RS28575	COG1475	DNA binding
HV292_RS28580	COG1475	DNA binding
HV292_RS28675	COG0732	type I restriction modification DNA specificity domain
HV292_RS28710	COG0328	RNA-DNA hybrid ribonuclease activity
HV292_RS28730	COG3039	Transposase
HV292_RS28735	COG1064	alcohol dehydrogenase
HV292_RS28745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV292_RS28770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HV292_RS28780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV292_RS28785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV292_RS28845	COG1216	Glycosyl transferase, family 2
HV292_RS28875	COG0463	Glycosyl transferase, family 2
HV292_RS28900	COG1127	ABC transporter
HV292_RS28905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV292_RS28920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV292_RS29035	COG3344	reverse transcriptase
HV292_RS29090	COG0629	single-stranded DNA binding
HV292_RS29180	COG3039	Transposase
HV292_RS29425	COG4644	lycopene metabolic process
HV292_RS29455	COG3039	Transposase
HV292_RS29530	COG3504	Conjugal transfer protein
HV292_RS29580	COG0250	Participates in transcription elongation, termination and antitermination