locus-tag	class	description
C6M02_RS00040	COG3064	Membrane
C6M02_RS00365	COG3344	reverse transcriptase
C6M02_RS00705	COG3039	Transposase
C6M02_RS00765	COG2135	peptidase activity
C6M02_RS00900	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C6M02_RS01155	COG3344	reverse transcriptase
C6M02_RS01175	COG5642	Protein of unknown function (DUF2384)
C6M02_RS01180	COG5654	RES domain protein
C6M02_RS01340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6M02_RS01415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C6M02_RS01470	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
C6M02_RS01480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6M02_RS01495	COG0500	methyltransferase
C6M02_RS01500	COG0523	cobalamin synthesis protein
C6M02_RS01610	COG1956	GAF domain-containing protein
C6M02_RS01615	COG1956	GAF domain-containing protein
C6M02_RS01695	COG1522	sequence-specific DNA binding
C6M02_RS01710	COG3321	synthase
C6M02_RS01710	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS01710	COG0604	alcohol dehydrogenase
C6M02_RS01830	COG1358	cellular component organization or biogenesis
C6M02_RS01850	COG4245	von Willebrand factor, type A
C6M02_RS01860	COG4245	von Willebrand factor, type A
C6M02_RS01865	COG4245	von Willebrand factor, type A
C6M02_RS01955	COG0789	Transcriptional regulator
C6M02_RS02120	COG3344	reverse transcriptase
C6M02_RS02230	COG0210	DNA helicase
C6M02_RS02240	COG2026	Addiction module toxin, RelE StbE family
C6M02_RS02250	COG0675	Transposase, IS605 OrfB family
C6M02_RS02265	COG0675	Transposase, IS605 OrfB family
C6M02_RS02565	COG1484	DNA-dependent DNA replication
C6M02_RS02620	COG0633	Ferredoxin
C6M02_RS02695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6M02_RS02720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6M02_RS02770	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6M02_RS02805	COG0739	heme binding
C6M02_RS02815	COG2132	Multicopper oxidase
C6M02_RS02820	COG3667	copper resistance
C6M02_RS02825	COG2372	response to copper ion
C6M02_RS02830	COG1276	copper resistance
C6M02_RS02835	COG0745	RESPONSE REGULATOR receiver
C6M02_RS02840	COG2205	protein histidine kinase activity
C6M02_RS02890	COG1620	l-lactate permease
C6M02_RS02895	COG0277	FAD linked oxidase domain protein
C6M02_RS02900	COG0247	lactate metabolic process
C6M02_RS02905	COG1139	Iron-sulfur cluster binding protein
C6M02_RS02910	COG1556	Lactate utilization protein
C6M02_RS02915	COG2610	gluconate transmembrane transporter activity
C6M02_RS02920	COG4680	protein conserved in bacteria
C6M02_RS03030	COG2003	Belongs to the UPF0758 family
C6M02_RS03115	COG0697	spore germination
C6M02_RS03195	COG3173	Aminoglycoside phosphotransferase
C6M02_RS03225	COG1349	DNA-binding transcription factor activity
C6M02_RS03285	COG0768	penicillin binding
C6M02_RS03310	COG1660	Displays ATPase and GTPase activities
C6M02_RS03360	COG3344	reverse transcriptase
C6M02_RS03445	COG0187	DNA topoisomerase II activity
C6M02_RS03450	COG0561	phosphatase activity
C6M02_RS03465	COG2186	Transcriptional regulator
C6M02_RS03470	COG3734	2-keto-3-deoxy-galactonokinase
C6M02_RS03475	COG0800	Aldolase
C6M02_RS03495	COG2271	Major facilitator Superfamily
C6M02_RS03500	COG0823	Involved in the tonB-independent uptake of proteins
C6M02_RS03505	COG5645	(Lipo)protein
C6M02_RS03520	COG3645	SOS response
C6M02_RS03530	COG2188	Transcriptional regulator
C6M02_RS03545	COG2149	membrane
C6M02_RS03565	COG2610	gluconate transmembrane transporter activity
C6M02_RS03570	COG0583	DNA-binding transcription factor activity
C6M02_RS03575	COG2814	Major facilitator Superfamily
C6M02_RS03600	COG0028	Belongs to the TPP enzyme family
C6M02_RS03605	COG0440	acetolactate synthase activity
C6M02_RS03610	COG2197	response regulator
C6M02_RS03620	COG2271	Major facilitator Superfamily
C6M02_RS03665	COG2188	Transcriptional regulator
C6M02_RS03700	COG4580	involved in the transport of maltose and maltodextrins
C6M02_RS03705	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6M02_RS03710	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS03710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS03720	COG1609	Transcriptional regulator
C6M02_RS03730	COG3384	dioxygenase
C6M02_RS03735	COG0583	DNA-binding transcription factor activity
C6M02_RS03740	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C6M02_RS03745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C6M02_RS03750	COG2828	Protein conserved in bacteria
C6M02_RS03765	COG0697	spore germination
C6M02_RS03770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6M02_RS03770	COG1263	PTS System
C6M02_RS03780	COG2814	Major facilitator Superfamily
C6M02_RS03790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6M02_RS03825	COG0583	DNA-binding transcription factor activity
C6M02_RS03850	COG1464	Belongs to the NlpA lipoprotein family
C6M02_RS03865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C6M02_RS03875	COG1064	alcohol dehydrogenase
C6M02_RS03910	COG2211	Major facilitator Superfamily
C6M02_RS03915	COG1501	Belongs to the glycosyl hydrolase 31 family
C6M02_RS03940	COG2842	Transposition protein
C6M02_RS03970	COG4382	Mu-like prophage protein Gp16
C6M02_RS04015	COG0640	Transcriptional regulator
C6M02_RS04030	COG4373	Mu-like prophage FluMu protein gp28
C6M02_RS04050	COG4397	Mu-like prophage major head subunit gpT
C6M02_RS04080	COG4386	tail sheath protein
C6M02_RS04090	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
C6M02_RS04110	COG4384	Bacteriophage Mu Gp45 protein
C6M02_RS04120	COG3299	homolog of phage Mu protein gp47
C6M02_RS04130	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6M02_RS04135	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C6M02_RS04140	COG5301	cellulose 1,4-beta-cellobiosidase activity
C6M02_RS04155	COG1486	melibiose metabolic process
C6M02_RS04160	COG1263	PTS System
C6M02_RS04160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6M02_RS04165	COG2982	Protein involved in outer membrane biogenesis
C6M02_RS04170	COG2233	PERMEase
C6M02_RS04175	COG0786	glutamate:sodium symporter activity
C6M02_RS04195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C6M02_RS04220	COG3152	Membrane
C6M02_RS04230	COG1494	fructose-1,6-bisphosphatase
C6M02_RS04235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C6M02_RS04240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6M02_RS04245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6M02_RS04265	COG2860	membrane
C6M02_RS04275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6M02_RS04275	COG2169	Transcriptional regulator
C6M02_RS04280	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C6M02_RS04285	COG1561	YicC-like family, N-terminal region
C6M02_RS04305	COG3039	Transposase
C6M02_RS04325	COG1131	(ABC) transporter
C6M02_RS04330	COG0842	Transport permease protein
C6M02_RS04355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6M02_RS04390	COG1519	Transferase
C6M02_RS04395	COG1216	Glycosyl transferase, family 2
C6M02_RS04400	COG0438	transferase activity, transferring glycosyl groups
C6M02_RS04410	COG0859	PFAM glycosyl transferase family 9
C6M02_RS04435	COG0859	PFAM glycosyl transferase family 9
C6M02_RS04450	COG0156	8-amino-7-oxononanoate synthase activity
C6M02_RS04460	COG0463	Glycosyl transferase, family 2
C6M02_RS04465	COG2861	carbohydrate metabolic process
C6M02_RS04470	COG4942	peptidase
C6M02_RS04480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6M02_RS04485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6M02_RS04505	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C6M02_RS04515	COG2186	Transcriptional regulator
C6M02_RS04535	COG3722	fumarate hydratase activity
C6M02_RS04555	COG1566	PFAM secretion protein HlyD family protein
C6M02_RS04560	COG0625	glutathione transferase activity
C6M02_RS04570	COG3276	selenocysteine insertion sequence binding
C6M02_RS04575	COG1414	Transcriptional regulator
C6M02_RS04580	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6M02_RS04585	COG3977	Valine--pyruvate aminotransferase
C6M02_RS04590	COG0366	Alpha amylase catalytic
C6M02_RS04600	COG2992	FlgJ-related protein
C6M02_RS04605	COG2207	Transcriptional regulator
C6M02_RS04605	COG1609	Transcriptional regulator
C6M02_RS04610	COG4214	carbohydrate transport
C6M02_RS04620	COG4213	ABC transporter substrate-binding protein
C6M02_RS04640	COG4682	membrane
C6M02_RS04645	COG4682	membrane
C6M02_RS04650	COG3274	enterobacterial common antigen metabolic process
C6M02_RS04690	COG1278	Cold shock
C6M02_RS04695	COG2944	sequence-specific DNA binding
C6M02_RS04700	COG2814	Major facilitator Superfamily
C6M02_RS04725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6M02_RS04735	COG1609	Transcriptional regulator
C6M02_RS04740	COG2885	chlorophyll binding
C6M02_RS04745	COG0243	molybdopterin cofactor binding
C6M02_RS04750	COG0456	acetyltransferase
C6M02_RS04755	COG2818	Glycosylase
C6M02_RS04760	COG5571	outer membrane autotransporter
C6M02_RS04765	COG2223	nitrite transmembrane transporter activity
C6M02_RS04805	COG0747	negative chemotaxis
C6M02_RS04810	COG0601	transmembrane transport
C6M02_RS04815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6M02_RS04820	COG0444	Belongs to the ABC transporter superfamily
C6M02_RS04825	COG4608	Belongs to the ABC transporter superfamily
C6M02_RS04850	COG1215	transferase activity, transferring glycosyl groups
C6M02_RS04855	COG0457	Tetratricopeptide repeat
C6M02_RS04870	COG2194	sulfuric ester hydrolase activity
C6M02_RS04900	COG1215	transferase activity, transferring glycosyl groups
C6M02_RS04905	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C6M02_RS04910	COG0457	Tetratricopeptide repeat
C6M02_RS04910	COG3118	belongs to the thioredoxin family
C6M02_RS04915	COG2199	diguanylate cyclase activity
C6M02_RS04915	COG2200	EAL domain
C6M02_RS04930	COG0612	Peptidase, M16
C6M02_RS04945	COG2982	Protein involved in outer membrane biogenesis
C6M02_RS04950	COG0477	Major facilitator Superfamily
C6M02_RS04955	COG1295	ribonuclease BN
C6M02_RS04960	COG0583	DNA-binding transcription factor activity
C6M02_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS04970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6M02_RS04980	COG1454	alcohol dehydrogenase
C6M02_RS04990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6M02_RS04995	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C6M02_RS05000	COG0671	phosphoesterase, PA-phosphatase related
C6M02_RS05020	COG0589	response to stress
C6M02_RS05030	COG0306	phosphate transporter
C6M02_RS05035	COG2081	HI0933 family
C6M02_RS05040	COG2239	Acts as a magnesium transporter
C6M02_RS05050	COG1124	(ABC) transporter
C6M02_RS05060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6M02_RS05065	COG0601	transmembrane transport
C6M02_RS05070	COG0747	negative chemotaxis
C6M02_RS05085	COG3479	Phenolic acid decarboxylase
C6M02_RS05125	COG0628	permease
C6M02_RS05130	COG0477	Major facilitator Superfamily
C6M02_RS05140	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C6M02_RS05155	COG3714	YhhN family
C6M02_RS05165	COG3776	membrane
C6M02_RS05170	COG0742	ribosomal rna small subunit methyltransferase
C6M02_RS05175	COG0552	protein localization to endoplasmic reticulum
C6M02_RS05180	COG2884	Cell division ATP-binding protein ftsE
C6M02_RS05185	COG2177	Part of the ABC transporter FtsEX involved in
C6M02_RS05200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6M02_RS05210	COG0683	leucine binding
C6M02_RS05225	COG0683	leucine binding
C6M02_RS05230	COG0559	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS05280	COG0584	glycerophosphoryl diester phosphodiesterase
C6M02_RS05290	COG0405	Gamma-glutamyltransferase
C6M02_RS05295	COG1247	-acetyltransferase
C6M02_RS05305	COG0673	inositol 2-dehydrogenase activity
C6M02_RS05310	COG1741	Belongs to the pirin family
C6M02_RS05315	COG1609	Transcriptional regulator
C6M02_RS05320	COG3265	gluconokinase activity
C6M02_RS05325	COG2610	gluconate transmembrane transporter activity
C6M02_RS05335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6M02_RS05360	COG0058	SHG alpha-glucan phosphorylase activity
C6M02_RS05375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C6M02_RS05390	COG1349	DNA-binding transcription factor activity
C6M02_RS05405	COG0058	SHG alpha-glucan phosphorylase activity
C6M02_RS05410	COG1640	4-alpha-glucanotransferase
C6M02_RS05415	COG2610	gluconate transmembrane transporter activity
C6M02_RS05425	COG1040	competence protein
C6M02_RS05450	COG1918	ferrous iron import across plasma membrane
C6M02_RS05455	COG2183	response to ionizing radiation
C6M02_RS05460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6M02_RS05485	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C6M02_RS05490	COG1011	Hydrolase
C6M02_RS05500	COG0494	nUDIX hydrolase
C6M02_RS05505	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C6M02_RS05530	COG4796	Type ii and iii secretion system protein
C6M02_RS05550	COG3266	domain, Protein
C6M02_RS05555	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C6M02_RS05560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6M02_RS05585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6M02_RS05590	COG0402	S-adenosylhomocysteine deaminase activity
C6M02_RS05595	COG0738	Major facilitator superfamily
C6M02_RS05620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6M02_RS05625	COG1289	transmembrane transporter activity
C6M02_RS05640	COG1765	OsmC-like protein
C6M02_RS05645	COG3954	Phosphoribulokinase
C6M02_RS05655	COG0429	hydrolase of the alpha beta-hydrolase fold
C6M02_RS05665	COG0488	(ABC) transporter
C6M02_RS05685	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C6M02_RS05690	COG1047	Peptidyl-prolyl cis-trans
C6M02_RS05700	COG0545	Peptidyl-prolyl cis-trans isomerase
C6M02_RS05705	COG2964	Protein conserved in bacteria
C6M02_RS05765	COG0051	transcription antitermination factor activity, RNA binding
C6M02_RS05790	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C6M02_RS05805	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C6M02_RS05870	COG0201	protein transport
C6M02_RS05895	COG0202	RNA polymerase activity
C6M02_RS05910	COG0789	Transcriptional regulator
C6M02_RS05915	COG3036	rescue of stalled ribosome
C6M02_RS05945	COG0758	DNA mediated transformation
C6M02_RS05955	COG0551	DNA topoisomerase type I activity
C6M02_RS05975	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6M02_RS06015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6M02_RS06020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6M02_RS06025	COG1309	transcriptional regulator
C6M02_RS06030	COG0582	viral genome integration into host DNA
C6M02_RS06045	COG3561	AntA/AntB antirepressor
C6M02_RS06135	COG1802	Transcriptional regulator
C6M02_RS06135	COG4626	Terminase
C6M02_RS06165	COG4145	pantothenate transmembrane transporter activity
C6M02_RS06170	COG3924	membrane
C6M02_RS06175	COG0439	Biotin carboxylase
C6M02_RS06180	COG0511	ligase activity, forming carbon-carbon bonds
C6M02_RS06210	COG2199	diguanylate cyclase activity
C6M02_RS06210	COG2200	EAL domain
C6M02_RS06220	COG1077	Cell shape determining protein MreB Mrl
C6M02_RS06225	COG1792	Involved in formation and maintenance of cell shape
C6M02_RS06230	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C6M02_RS06240	COG1530	ribonuclease E activity
C6M02_RS06245	COG3164	Protein of unknown function
C6M02_RS06250	COG0312	modulator of DNA gyrase
C6M02_RS06255	COG0583	DNA-binding transcription factor activity
C6M02_RS06270	COG1289	transmembrane transporter activity
C6M02_RS06275	COG2732	(Barnase) inhibitor
C6M02_RS06300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6M02_RS06305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6M02_RS06310	COG3105	Protein conserved in bacteria
C6M02_RS06315	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C6M02_RS06335	COG0625	glutathione transferase activity
C6M02_RS06340	COG2969	positive regulation of protein catabolic process
C6M02_RS06350	COG0493	'glutamate synthase
C6M02_RS06355	COG0070	glutamate synthase
C6M02_RS06355	COG0069	glutamate synthase activity
C6M02_RS06355	COG0067	glutamate synthase
C6M02_RS06365	COG1242	4 iron, 4 sulfur cluster binding
C6M02_RS06370	COG2271	Major facilitator Superfamily
C6M02_RS06375	COG1063	alcohol dehydrogenase
C6M02_RS06380	COG1312	Catalyzes the dehydration of D-mannonate
C6M02_RS06385	COG0784	Response regulator, receiver
C6M02_RS06385	COG2198	Histidine kinase
C6M02_RS06385	COG5002	protein histidine kinase activity
C6M02_RS06390	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C6M02_RS06395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6M02_RS06400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS06410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS06415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6M02_RS06420	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C6M02_RS06425	COG1137	ATPase activity
C6M02_RS06430	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C6M02_RS06435	COG3117	lipopolysaccharide transmembrane transporter activity
C6M02_RS06440	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C6M02_RS06450	COG0530	calcium, potassium:sodium antiporter activity
C6M02_RS06460	COG1127	ABC transporter
C6M02_RS06465	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C6M02_RS06470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6M02_RS06475	COG2854	intermembrane phospholipid transfer
C6M02_RS06480	COG3113	response to antibiotic
C6M02_RS06485	COG5007	Belongs to the BolA IbaG family
C6M02_RS06495	COG3423	Transcriptional regulator
C6M02_RS06500	COG0142	geranyltranstransferase activity
C6M02_RS06515	COG0697	spore germination
C6M02_RS06525	COG2027	D-alanyl-D-alanine carboxypeptidase
C6M02_RS06535	COG1534	Rna-binding protein
C6M02_RS06545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6M02_RS06550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C6M02_RS06560	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6M02_RS06600	COG0195	Participates in both transcription termination and antitermination
C6M02_RS06650	COG0814	amino acid
C6M02_RS06655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6M02_RS06660	COG0826	peptidase U32
C6M02_RS06665	COG0826	peptidase U32
C6M02_RS06670	COG3154	lipid carrier protein
C6M02_RS06675	COG3153	acetyltransferase
C6M02_RS06690	COG0693	protein deglycase activity
C6M02_RS06695	COG0702	epimerase
C6M02_RS06700	COG0701	Predicted permease
C6M02_RS06705	COG2823	Periplasmic or secreted lipoprotein
C6M02_RS06725	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C6M02_RS06740	COG1063	alcohol dehydrogenase
C6M02_RS06745	COG3775	system Galactitol-specific IIC component
C6M02_RS06750	COG3414	Phosphotransferase system galactitol-specific IIB component
C6M02_RS06755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS06765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS06765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS06770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS06770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6M02_RS06770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6M02_RS06775	COG1105	Belongs to the carbohydrate kinase PfkB family
C6M02_RS06785	COG1349	DNA-binding transcription factor activity
C6M02_RS06790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6M02_RS06795	COG2721	sulfolactate sulfo-lyase activity
C6M02_RS06800	COG2271	Major facilitator Superfamily
C6M02_RS06810	COG2084	Dehydrogenase
C6M02_RS06815	COG1929	Belongs to the glycerate kinase type-1 family
C6M02_RS06835	COG1741	Belongs to the pirin family
C6M02_RS06840	COG0583	DNA-binding transcription factor activity
C6M02_RS06845	COG3152	Membrane
C6M02_RS06850	COG0435	Glutathione S-transferase
C6M02_RS06855	COG2259	Doxx family
C6M02_RS06865	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C6M02_RS06870	COG4575	ribosome binding
C6M02_RS06875	COG1422	Protein of unknown function (DUF1090)
C6M02_RS06885	COG0586	Pfam SNARE associated Golgi protein
C6M02_RS06890	COG2186	Transcriptional regulator
C6M02_RS06895	COG2271	Major facilitator Superfamily
C6M02_RS06905	COG2721	sulfolactate sulfo-lyase activity
C6M02_RS06920	COG0861	Integral membrane protein TerC family
C6M02_RS06925	COG0673	inositol 2-dehydrogenase activity
C6M02_RS06930	COG1451	nucleotide metabolic process
C6M02_RS06950	COG1902	pentaerythritol trinitrate reductase activity
C6M02_RS06950	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6M02_RS07005	COG1695	Transcriptional regulator
C6M02_RS07010	COG2375	cellular response to nickel ion
C6M02_RS07025	COG1461	Dihydroxyacetone kinase
C6M02_RS07030	COG2376	Dihydroxyacetone kinase
C6M02_RS07110	COG3247	response to pH
C6M02_RS07135	COG2197	response regulator
C6M02_RS07160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6M02_RS07165	COG0358	DNA primase activity
C6M02_RS07170	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C6M02_RS07240	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6M02_RS07255	COG4991	sh3 domain protein
C6M02_RS07260	COG3025	triphosphatase activity
C6M02_RS07280	COG2960	long-chain fatty acid transporting porin activity
C6M02_RS07295	COG3384	dioxygenase
C6M02_RS07300	COG0754	glutathionylspermidine amidase activity
C6M02_RS07315	COG0494	nUDIX hydrolase
C6M02_RS07320	COG3151	Protein conserved in bacteria
C6M02_RS07325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C6M02_RS07330	COG3150	esterase
C6M02_RS07340	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C6M02_RS07345	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6M02_RS07350	COG0642	Histidine kinase
C6M02_RS07360	COG3111	PFAM Bacterial OB fold (BOF) protein
C6M02_RS07365	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C6M02_RS07370	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6M02_RS07375	COG0204	Acyl-transferase
C6M02_RS07380	COG2132	Multicopper oxidase
C6M02_RS07385	COG1032	radical SAM domain protein
C6M02_RS07395	COG0656	L-ascorbic acid biosynthetic process
C6M02_RS07400	COG1979	alcohol dehydrogenase
C6M02_RS07405	COG2207	Transcriptional regulator
C6M02_RS07410	COG0586	Pfam SNARE associated Golgi protein
C6M02_RS07415	COG0626	cystathionine gamma-synthase activity
C6M02_RS07430	COG0848	biopolymer transport protein
C6M02_RS07435	COG2211	Major facilitator Superfamily
C6M02_RS07460	COG0625	glutathione transferase activity
C6M02_RS07470	COG0754	glutathionylspermidine amidase activity
C6M02_RS07475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6M02_RS07495	COG0583	DNA-binding transcription factor activity
C6M02_RS07500	COG0626	cystathionine gamma-synthase activity
C6M02_RS07765	COG3423	Transcriptional regulator
C6M02_RS07775	COG1278	Cold shock
C6M02_RS07780	COG3423	Transcriptional regulator
C6M02_RS07855	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C6M02_RS07865	COG1811	Na channel or pump
C6M02_RS07875	COG1982	Orn Lys Arg decarboxylase major
C6M02_RS07880	COG2211	Major facilitator Superfamily
C6M02_RS07895	COG1194	a g-specific adenine glycosylase
C6M02_RS07905	COG3171	Protein conserved in bacteria
C6M02_RS07915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6M02_RS07930	COG0762	integral membrane protein
C6M02_RS07935	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C6M02_RS07940	COG2805	Type II/IV secretion system protein
C6M02_RS07960	COG0189	ligase activity
C6M02_RS07965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6M02_RS07970	COG2356	endonuclease I
C6M02_RS07980	COG2814	Major facilitator Superfamily
C6M02_RS08020	COG2146	nitrite reductase [NAD(P)H] activity
C6M02_RS08035	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS08040	COG1414	Transcriptional regulator
C6M02_RS08070	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS08075	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
C6M02_RS08105	COG0501	Belongs to the peptidase M48B family
C6M02_RS08110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6M02_RS08125	COG0191	fructose-bisphosphate aldolase activity
C6M02_RS08130	COG0668	transmembrane transport
C6M02_RS08140	COG2968	Membrane
C6M02_RS08155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6M02_RS08160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C6M02_RS08180	COG0006	proline dipeptidase activity
C6M02_RS08185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6M02_RS08190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6M02_RS08210	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS08215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6M02_RS08235	COG2723	6-phospho-beta-galactosidase activity
C6M02_RS08240	COG1737	Transcriptional regulator
C6M02_RS08250	COG1272	protein, Hemolysin III
C6M02_RS08260	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C6M02_RS08270	COG0716	FMN binding
C6M02_RS08275	COG4974	Belongs to the 'phage' integrase family
C6M02_RS08285	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C6M02_RS08310	COG4942	peptidase
C6M02_RS08320	COG2814	Major facilitator Superfamily
C6M02_RS08335	COG0667	Aldo Keto reductase
C6M02_RS08370	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6M02_RS08375	COG1393	Belongs to the ArsC family
C6M02_RS08390	COG1538	Outer membrane efflux protein
C6M02_RS08395	COG1289	transmembrane transporter activity
C6M02_RS08410	COG3592	Divergent 4Fe-4S mono-cluster
C6M02_RS08415	COG2388	GCN5-related N-acetyl-transferase
C6M02_RS08425	COG3539	Fimbrial protein
C6M02_RS08430	COG3539	Fimbrial protein
C6M02_RS08435	COG3539	Fimbrial protein
C6M02_RS08440	COG3188	usher protein
C6M02_RS08445	COG3121	Chaperone
C6M02_RS08450	COG3539	Fimbrial protein
C6M02_RS08460	COG4974	Belongs to the 'phage' integrase family
C6M02_RS08465	COG0582	viral genome integration into host DNA
C6M02_RS08475	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C6M02_RS08480	COG1846	Transcriptional regulator
C6M02_RS08485	COG0697	spore germination
C6M02_RS08545	COG0667	Aldo Keto reductase
C6M02_RS08550	COG0814	amino acid
C6M02_RS08565	COG0183	Belongs to the thiolase family
C6M02_RS08575	COG0823	Involved in the tonB-independent uptake of proteins
C6M02_RS08580	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS08585	COG2814	Major facilitator Superfamily
C6M02_RS08615	COG3842	ATPase activity
C6M02_RS08620	COG0395	ABC-type sugar transport system, permease component
C6M02_RS08625	COG1175	transmembrane transport
C6M02_RS08630	COG1917	Cupin 2, conserved barrel domain protein
C6M02_RS08635	COG1794	racemase activity, acting on amino acids and derivatives
C6M02_RS08640	COG0583	DNA-binding transcription factor activity
C6M02_RS08650	COG1609	Transcriptional regulator
C6M02_RS08655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS08660	COG2723	6-phospho-beta-galactosidase activity
C6M02_RS08665	COG2186	Transcriptional regulator
C6M02_RS08675	COG1609	Transcriptional regulator
C6M02_RS08700	COG0667	Aldo Keto reductase
C6M02_RS08710	COG0861	Integral membrane protein TerC family
C6M02_RS08740	COG2165	general secretion pathway protein
C6M02_RS08745	COG4795	General secretion pathway protein
C6M02_RS08755	COG4967	type IV pilus modification protein PilV
C6M02_RS08760	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C6M02_RS08765	COG1025	Belongs to the peptidase M16 family
C6M02_RS08770	COG1074	ATP-dependent DNA helicase activity
C6M02_RS08775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6M02_RS08785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C6M02_RS08785	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C6M02_RS08790	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6M02_RS08795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C6M02_RS08825	COG4656	Part of a membrane complex involved in electron transport
C6M02_RS08830	COG1454	alcohol dehydrogenase
C6M02_RS08830	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS08860	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C6M02_RS09025	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C6M02_RS09030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C6M02_RS09035	COG2166	iron-sulfur cluster assembly
C6M02_RS09040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C6M02_RS09050	COG0583	DNA-binding transcription factor activity
C6M02_RS09055	COG2363	Small membrane protein
C6M02_RS09065	COG1349	DNA-binding transcription factor activity
C6M02_RS09085	COG0738	Major facilitator superfamily
C6M02_RS09090	COG0235	Class ii aldolase
C6M02_RS09095	COG1454	alcohol dehydrogenase
C6M02_RS09110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6M02_RS09125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6M02_RS09130	COG2011	ABC-type metal ion transport system permease component
C6M02_RS09135	COG1464	Belongs to the NlpA lipoprotein family
C6M02_RS09145	COG0477	Major facilitator Superfamily
C6M02_RS09155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6M02_RS09160	COG1760	l-serine dehydratase
C6M02_RS09165	COG0814	amino acid
C6M02_RS09170	COG1611	Belongs to the LOG family
C6M02_RS09185	COG3098	single-species biofilm formation
C6M02_RS09190	COG0564	pseudouridine synthase activity
C6M02_RS09195	COG0716	FMN binding
C6M02_RS09200	COG2271	Major facilitator Superfamily
C6M02_RS09205	COG4948	Mandelate Racemase Muconate Lactonizing
C6M02_RS09210	COG4948	Mandelate Racemase Muconate Lactonizing
C6M02_RS09215	COG1929	Belongs to the glycerate kinase type-1 family
C6M02_RS09220	COG3850	Histidine kinase
C6M02_RS09220	COG4999	Histidine kinase
C6M02_RS09220	COG2205	protein histidine kinase activity
C6M02_RS09220	COG3437	response regulator, receiver
C6M02_RS09230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6M02_RS09235	COG3956	TIGRFAM MazG family protein
C6M02_RS09255	COG0602	queuosine metabolic process
C6M02_RS09260	COG0720	synthase
C6M02_RS09280	COG2234	aminopeptidase activity
C6M02_RS09340	COG4942	peptidase
C6M02_RS09340	COG1388	LysM domain
C6M02_RS09345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6M02_RS09370	COG0163	prenyltransferase activity
C6M02_RS09375	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C6M02_RS09420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6M02_RS09425	COG4558	Periplasmic binding protein
C6M02_RS09430	COG3720	iron ion transport
C6M02_RS09475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6M02_RS09480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6M02_RS09485	COG1121	(ABC) transporter
C6M02_RS09490	COG0803	Belongs to the bacterial solute-binding protein 9 family
C6M02_RS09495	COG1609	Transcriptional regulator
C6M02_RS09500	COG1940	carbohydrate kinase activity
C6M02_RS09505	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6M02_RS09510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS09515	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS09520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS09530	COG4580	involved in the transport of maltose and maltodextrins
C6M02_RS09540	COG2723	6-phospho-beta-galactosidase activity
C6M02_RS09550	COG0309	Hydrogenase expression formation protein (HypE)
C6M02_RS09555	COG0409	Hydrogenase expression formation protein
C6M02_RS09560	COG0298	carbon dioxide binding
C6M02_RS09565	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C6M02_RS09585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6M02_RS09590	COG0651	ATP synthesis coupled electron transport
C6M02_RS09595	COG0650	Formate hydrogenlyase subunit 4
C6M02_RS09600	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C6M02_RS09600	COG3261	NADH dehydrogenase
C6M02_RS09605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6M02_RS09610	COG3260	NADH ubiquinone oxidoreductase 20
C6M02_RS09620	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C6M02_RS09630	COG2723	6-phospho-beta-galactosidase activity
C6M02_RS09635	COG1263	PTS System
C6M02_RS09635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6M02_RS09640	COG1609	Transcriptional regulator
C6M02_RS09645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6M02_RS09650	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C6M02_RS09655	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
C6M02_RS09685	COG1349	DNA-binding transcription factor activity
C6M02_RS09690	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS09695	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS09705	COG3732	PTS system glucitol sorbitol-specific
C6M02_RS09710	COG3730	PTS system glucitol sorbitol-specific
C6M02_RS09715	COG2951	lytic endotransglycosylase activity
C6M02_RS09725	COG1121	(ABC) transporter
C6M02_RS09730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6M02_RS09740	COG1546	Belongs to the CinA family
C6M02_RS09765	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C6M02_RS09795	COG2823	Periplasmic or secreted lipoprotein
C6M02_RS09800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6M02_RS09805	COG1238	metal cluster binding
C6M02_RS09825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C6M02_RS09830	COG2814	Major facilitator Superfamily
C6M02_RS09835	COG1566	PFAM secretion protein HlyD family protein
C6M02_RS09840	COG1846	Transcriptional regulator
C6M02_RS09850	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C6M02_RS09860	COG4176	ABC-type proline glycine betaine transport system permease component
C6M02_RS09875	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6M02_RS09885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6M02_RS09890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6M02_RS09895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6M02_RS09900	COG4575	ribosome binding
C6M02_RS09925	COG2916	Histone family protein nucleoid-structuring protein H-NS
C6M02_RS09940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6M02_RS09945	COG0640	Transcriptional regulator
C6M02_RS09955	COG0583	DNA-binding transcription factor activity
C6M02_RS09960	COG3284	Transcriptional regulator
C6M02_RS09970	COG3539	Fimbrial protein
C6M02_RS09975	COG3121	Chaperone
C6M02_RS09995	COG3188	usher protein
C6M02_RS10005	COG3539	Fimbrial protein
C6M02_RS10010	COG2197	response regulator
C6M02_RS10030	COG4974	Belongs to the 'phage' integrase family
C6M02_RS10065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6M02_RS10085	COG3344	reverse transcriptase
C6M02_RS10130	COG4695	Portal protein
C6M02_RS10295	COG2867	negative regulation of translational initiation
C6M02_RS10310	COG0497	DNA recombination
C6M02_RS10330	COG4536	flavin adenine dinucleotide binding
C6M02_RS10335	COG4137	Cytochrome C assembly protein
C6M02_RS10340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6M02_RS10375	COG2885	chlorophyll binding
C6M02_RS10380	COG2199	diguanylate cyclase activity
C6M02_RS10390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6M02_RS10395	COG1605	Chorismate mutase
C6M02_RS10395	COG0287	Prephenate dehydrogenase
C6M02_RS10405	COG1605	Chorismate mutase
C6M02_RS10405	COG0077	Prephenate dehydratase
C6M02_RS10415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6M02_RS10420	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6M02_RS10435	COG0542	response to heat
C6M02_RS10460	COG0477	Major facilitator Superfamily
C6M02_RS10465	COG5544	Lipoprotein
C6M02_RS10470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6M02_RS10480	COG3148	PFAM DTW domain containing protein
C6M02_RS10485	COG3118	belongs to the thioredoxin family
C6M02_RS10490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6M02_RS10505	COG0513	Belongs to the DEAD box helicase family
C6M02_RS10515	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C6M02_RS10525	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C6M02_RS10530	COG3026	antisigma factor binding
C6M02_RS10535	COG3086	response to oxidative stress
C6M02_RS10545	COG0681	Belongs to the peptidase S26 family
C6M02_RS10565	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C6M02_RS10575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6M02_RS10580	COG1737	Transcriptional regulator
C6M02_RS10585	COG0560	Phosphoserine phosphatase
C6M02_RS10600	COG0047	phosphoribosylformylglycinamidine synthase activity
C6M02_RS10600	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C6M02_RS10605	COG2205	protein histidine kinase activity
C6M02_RS10610	COG3170	Tfp pilus assembly protein FimV
C6M02_RS10615	COG2204	response regulator
C6M02_RS10620	COG0347	Belongs to the P(II) protein family
C6M02_RS10625	COG1017	nitric oxide dioxygenase activity
C6M02_RS10625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6M02_RS10640	COG2259	Doxx family
C6M02_RS10645	COG1940	carbohydrate kinase activity
C6M02_RS10650	COG0457	Tetratricopeptide repeat
C6M02_RS10655	COG2814	Major facilitator Superfamily
C6M02_RS10655	COG0477	Major facilitator Superfamily
C6M02_RS10660	COG2017	converts alpha-aldose to the beta-anomer
C6M02_RS10665	COG2814	Major facilitator Superfamily
C6M02_RS10670	COG3711	transcriptional antiterminator
C6M02_RS10675	COG3683	transport system, periplasmic component
C6M02_RS10680	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C6M02_RS10710	COG0822	iron-sulfur transferase activity
C6M02_RS10730	COG0633	Ferredoxin
C6M02_RS10735	COG2975	iron-sulfur cluster assembly
C6M02_RS10755	COG2897	thiosulfate sulfurtransferase activity
C6M02_RS10760	COG2373	Large extracellular alpha-helical protein
C6M02_RS10765	COG4953	penicillin-binding protein 1C
C6M02_RS10800	COG2976	Protein conserved in bacteria
C6M02_RS10820	COG1645	bacterial-type flagellum-dependent swarming motility
C6M02_RS10830	COG0517	IMP dehydrogenase activity
C6M02_RS10830	COG0516	GMP reductase activity
C6M02_RS10885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6M02_RS10955	COG3344	reverse transcriptase
C6M02_RS10965	COG5484	DNA packaging
C6M02_RS10965	COG3728	DNA packaging
C6M02_RS11075	COG3617	BRO family, N-terminal domain
C6M02_RS11105	COG3179	chitinase
C6M02_RS11115	COG3119	arylsulfatase activity
C6M02_RS11120	COG0641	radical SAM
C6M02_RS11140	COG2200	EAL domain
C6M02_RS11155	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6M02_RS11170	COG2723	6-phospho-beta-galactosidase activity
C6M02_RS11180	COG2233	PERMEase
C6M02_RS11195	COG1393	Belongs to the ArsC family
C6M02_RS11200	COG4783	chaperone-mediated protein folding
C6M02_RS11205	COG0628	permease
C6M02_RS11210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C6M02_RS11215	COG2716	regulation of RNA biosynthetic process
C6M02_RS11225	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C6M02_RS11235	COG2321	neutral zinc metallopeptidase
C6M02_RS11240	COG1444	tRNA N-acetyltransferase activity
C6M02_RS11245	COG0400	carboxylic ester hydrolase activity
C6M02_RS11260	COG1393	Belongs to the ArsC family
C6M02_RS11270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6M02_RS11280	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C6M02_RS11280	COG0493	'glutamate synthase
C6M02_RS11290	COG5342	invasion associated locus B
C6M02_RS11295	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C6M02_RS11300	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6M02_RS11310	COG4810	utilization protein
C6M02_RS11400	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6M02_RS11420	COG2837	iron assimilation
C6M02_RS11430	COG4150	thiosulfate binding
C6M02_RS11435	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C6M02_RS11440	COG4208	sulfate ABC transporter
C6M02_RS11445	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C6M02_RS11455	COG4319	ketosteroid isomerase
C6M02_RS11490	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6M02_RS11510	COG3530	Putative quorum-sensing-regulated virulence factor
C6M02_RS11515	COG0385	Bile acid
C6M02_RS11520	COG0583	DNA-binding transcription factor activity
C6M02_RS11555	COG3415	Transposase
C6M02_RS11560	COG3415	Transposase
C6M02_RS11575	COG2200	EAL domain
C6M02_RS11575	COG2199	diguanylate cyclase activity
C6M02_RS11580	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6M02_RS11595	COG0667	Aldo Keto reductase
C6M02_RS11600	COG3961	Belongs to the TPP enzyme family
C6M02_RS11615	COG3279	Response regulator of the LytR AlgR family
C6M02_RS11620	COG3275	phosphorelay sensor kinase activity
C6M02_RS11630	COG0436	Aminotransferase
C6M02_RS11640	COG2807	transmembrane transport
C6M02_RS11645	COG0590	tRNA wobble adenosine to inosine editing
C6M02_RS11650	COG0583	DNA-binding transcription factor activity
C6M02_RS11670	COG2116	formate transmembrane transporter activity
C6M02_RS11675	COG2853	Lipoprotein
C6M02_RS11690	COG3691	Protein conserved in bacteria
C6M02_RS11705	COG2062	phosphohistidine phosphatase, SixA
C6M02_RS11730	COG0730	response to heat
C6M02_RS11735	COG3101	peptidyl-lysine hydroxylation
C6M02_RS11750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6M02_RS11770	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6M02_RS11780	COG0586	Pfam SNARE associated Golgi protein
C6M02_RS11790	COG0285	dihydrofolate synthase activity
C6M02_RS11795	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C6M02_RS11800	COG1286	toxin biosynthetic process
C6M02_RS11805	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C6M02_RS11810	COG0163	prenyltransferase activity
C6M02_RS11830	COG4160	amino acid transport
C6M02_RS11835	COG4598	ABC transporter
C6M02_RS11845	COG1090	epimerase
C6M02_RS11850	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6M02_RS11855	COG0625	glutathione transferase activity
C6M02_RS11860	COG0625	glutathione transferase activity
C6M02_RS11865	COG0622	Phosphoesterase
C6M02_RS11870	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C6M02_RS11875	COG0280	phosphate acetyltransferase
C6M02_RS11875	COG0857	belongs to the CobB CobQ family
C6M02_RS11895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6M02_RS11900	COG0471	metal ion transport
C6M02_RS11900	COG0490	domain, Protein
C6M02_RS11910	COG0436	Aminotransferase
C6M02_RS11915	COG0583	DNA-binding transcription factor activity
C6M02_RS11970	COG0839	Belongs to the complex I subunit 6 family
C6M02_RS11980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6M02_RS11985	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6M02_RS12000	COG2153	protein acetylation
C6M02_RS12005	COG1169	isochorismate synthase
C6M02_RS12030	COG0318	PFAM AMP-dependent synthetase and ligase
C6M02_RS12040	COG5464	transposase or invertase
C6M02_RS12055	COG1414	Transcriptional regulator
C6M02_RS12065	COG2271	Major facilitator Superfamily
C6M02_RS12075	COG0247	lactate metabolic process
C6M02_RS12085	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C6M02_RS12090	COG2271	Major facilitator Superfamily
C6M02_RS12095	COG0584	glycerophosphoryl diester phosphodiesterase
C6M02_RS12105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6M02_RS12135	COG2205	protein histidine kinase activity
C6M02_RS12135	COG0784	Response regulator, receiver
C6M02_RS12145	COG0642	Histidine kinase
C6M02_RS12145	COG2198	Histidine kinase
C6M02_RS12160	COG2169	Transcriptional regulator
C6M02_RS12160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6M02_RS12165	COG3145	DNA-N1-methyladenine dioxygenase activity
C6M02_RS12170	COG4615	Cyclic peptide transporter
C6M02_RS12175	COG2239	Acts as a magnesium transporter
C6M02_RS12180	COG0659	secondary active sulfate transmembrane transporter activity
C6M02_RS12195	COG0628	permease
C6M02_RS12220	COG1349	DNA-binding transcription factor activity
C6M02_RS12225	COG0494	nUDIX hydrolase
C6M02_RS12245	COG1061	Type III restriction enzyme res subunit
C6M02_RS12250	COG1187	pseudouridine synthase activity
C6M02_RS12255	COG2814	Major facilitator Superfamily
C6M02_RS12265	COG4172	Belongs to the ABC transporter superfamily
C6M02_RS12270	COG4239	(ABC) transporter, permease
C6M02_RS12275	COG4174	ABC transporter (Permease)
C6M02_RS12280	COG4166	transmembrane transport
C6M02_RS12285	COG2200	EAL domain
C6M02_RS12290	COG0791	NLP P60 protein
C6M02_RS12295	COG0671	phosphoesterase, PA-phosphatase related
C6M02_RS12300	COG0523	cobalamin synthesis protein
C6M02_RS12305	COG0246	Mannitol dehydrogenase
C6M02_RS12310	COG1312	Catalyzes the dehydration of D-mannonate
C6M02_RS12340	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS12340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS12345	COG1105	Belongs to the carbohydrate kinase PfkB family
C6M02_RS12350	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C6M02_RS12350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6M02_RS12350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6M02_RS12360	COG2855	membrane
C6M02_RS12370	COG0583	DNA-binding transcription factor activity
C6M02_RS12375	COG0833	amino acid
C6M02_RS12390	COG4771	TonB-dependent receptor
C6M02_RS12405	COG2311	Membrane
C6M02_RS12420	COG1129	ABC transporter
C6M02_RS12430	COG2949	membrane
C6M02_RS12445	COG1346	cytolysis
C6M02_RS12455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6M02_RS12460	COG3659	wide pore channel activity
C6M02_RS12475	COG2723	6-phospho-beta-galactosidase activity
C6M02_RS12480	COG1538	Outer membrane efflux protein
C6M02_RS12485	COG0586	Pfam SNARE associated Golgi protein
C6M02_RS12495	COG1686	Belongs to the peptidase S11 family
C6M02_RS12505	COG0277	FAD linked oxidase domain protein
C6M02_RS12510	COG1472	Belongs to the glycosyl hydrolase 3 family
C6M02_RS12515	COG1732	Glycine betaine
C6M02_RS12520	COG1174	glycine betaine transport
C6M02_RS12525	COG1125	glycine betaine transport
C6M02_RS12530	COG1174	glycine betaine transport
C6M02_RS12540	COG3275	phosphorelay sensor kinase activity
C6M02_RS12550	COG4807	Protein conserved in bacteria
C6M02_RS12570	COG5455	response to cobalt ion
C6M02_RS12575	COG0583	DNA-binding transcription factor activity
C6M02_RS12580	COG2252	PERMEase
C6M02_RS12590	COG0583	DNA-binding transcription factor activity
C6M02_RS12605	COG0351	phosphomethylpyrimidine kinase
C6M02_RS12610	COG1830	Aldolase
C6M02_RS12645	COG1070	Carbohydrate kinase
C6M02_RS12655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6M02_RS12660	COG4948	Mandelate Racemase Muconate Lactonizing
C6M02_RS12665	COG0747	negative chemotaxis
C6M02_RS12670	COG0601	transmembrane transport
C6M02_RS12675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6M02_RS12680	COG0444	Belongs to the ABC transporter superfamily
C6M02_RS12685	COG4608	Belongs to the ABC transporter superfamily
C6M02_RS12695	COG0826	peptidase U32
C6M02_RS12700	COG0745	RESPONSE REGULATOR receiver
C6M02_RS12705	COG2205	protein histidine kinase activity
C6M02_RS12730	COG1301	dicarboxylic acid transport
C6M02_RS12745	COG5002	protein histidine kinase activity
C6M02_RS12750	COG0443	Heat shock 70 kDa protein
C6M02_RS12760	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C6M02_RS12775	COG2982	Protein involved in outer membrane biogenesis
C6M02_RS12780	COG1253	flavin adenine dinucleotide binding
C6M02_RS12840	COG0463	Glycosyl transferase, family 2
C6M02_RS12855	COG2244	polysaccharide biosynthetic process
C6M02_RS12865	COG1088	dTDP-glucose 4,6-dehydratase activity
C6M02_RS12900	COG1088	dTDP-glucose 4,6-dehydratase activity
C6M02_RS12965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C6M02_RS12995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6M02_RS13000	COG0583	DNA-binding transcription factor activity
C6M02_RS13010	COG0531	amino acid
C6M02_RS13015	COG0640	Transcriptional regulator
C6M02_RS13020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C6M02_RS13025	COG2925	Exonuclease
C6M02_RS13040	COG3344	reverse transcriptase
C6M02_RS13050	COG1289	transmembrane transporter activity
C6M02_RS13070	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C6M02_RS13080	COG1942	4-Oxalocrotonate Tautomerase
C6M02_RS13085	COG0583	DNA-binding transcription factor activity
C6M02_RS13090	COG0095	Lipoate-protein ligase
C6M02_RS13095	COG0477	Major facilitator Superfamily
C6M02_RS13110	COG5001	Diguanylate cyclase
C6M02_RS13110	COG3300	MHYT domain
C6M02_RS13120	COG3615	Tellurite resistance protein tehB
C6M02_RS13145	COG3706	GGDEF domain
C6M02_RS13210	COG2003	Belongs to the UPF0758 family
C6M02_RS13265	COG3504	Conjugal transfer protein
C6M02_RS13330	COG4771	TonB-dependent receptor
C6M02_RS13335	COG1021	2,3-dihydroxybenzoate-AMP ligase
C6M02_RS13355	COG2226	methyltransferase
C6M02_RS13355	COG3433	isochorismatase activity
C6M02_RS13355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6M02_RS13370	COG1132	(ABC) transporter
C6M02_RS13375	COG2814	Major facilitator Superfamily
C6M02_RS13380	COG1169	isochorismate synthase
C6M02_RS13385	COG0582	viral genome integration into host DNA
C6M02_RS13395	COG0534	Mate efflux family protein
C6M02_RS13405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C6M02_RS13425	COG0604	alcohol dehydrogenase
C6M02_RS13430	COG1309	transcriptional regulator
C6M02_RS13435	COG0025	NhaP-type Na H and K H
C6M02_RS13480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6M02_RS13490	COG1418	mRNA catabolic process
C6M02_RS13495	COG0270	DNA (cytosine-5-)-methyltransferase activity
C6M02_RS13500	COG3727	T/G mismatch-specific endonuclease activity
C6M02_RS13505	COG0697	spore germination
C6M02_RS13510	COG2354	Protein conserved in bacteria
C6M02_RS13540	COG0366	Alpha amylase catalytic
C6M02_RS13545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6M02_RS13555	COG0765	amino acid transport
C6M02_RS13560	COG1126	abc transporter atp-binding protein
C6M02_RS13565	COG2197	response regulator
C6M02_RS13575	COG2197	response regulator
C6M02_RS13615	COG3318	Belongs to the UPF0149 family
C6M02_RS13615	COG3012	SEC-C Motif Domain Protein
C6M02_RS13620	COG0814	amino acid
C6M02_RS13630	COG1528	Iron-storage protein
C6M02_RS13645	COG0477	Major facilitator Superfamily
C6M02_RS13655	COG2211	Major facilitator Superfamily
C6M02_RS13665	COG1528	Iron-storage protein
C6M02_RS13675	COG1879	ABC-type sugar transport system periplasmic component
C6M02_RS13685	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS13710	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C6M02_RS13720	COG3102	Protein conserved in bacteria
C6M02_RS13740	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C6M02_RS13745	COG1801	Protein of unknown function DUF72
C6M02_RS13750	COG1335	isochorismatase
C6M02_RS13760	COG0494	nUDIX hydrolase
C6M02_RS13785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6M02_RS13795	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C6M02_RS13800	COG0739	heme binding
C6M02_RS13805	COG1560	Kdo2-lipid A biosynthetic process
C6M02_RS13815	COG1737	Transcriptional regulator
C6M02_RS13830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C6M02_RS13835	COG0129	dihydroxy-acid dehydratase activity
C6M02_RS13840	COG0800	Aldolase
C6M02_RS13850	COG3141	response to X-ray
C6M02_RS13855	COG2979	Protein of unknown function (DUF533)
C6M02_RS13860	COG1770	oligopeptidase
C6M02_RS13865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6M02_RS13875	COG2372	response to copper ion
C6M02_RS13880	COG1276	copper resistance
C6M02_RS13895	COG2990	Protein conserved in bacteria
C6M02_RS13920	COG3008	intermembrane lipid transfer
C6M02_RS13925	COG2995	paraquat-inducible protein a
C6M02_RS13930	COG1956	GAF domain-containing protein
C6M02_RS13950	COG2814	Major facilitator Superfamily
C6M02_RS13960	COG1414	Transcriptional regulator
C6M02_RS14000	COG0768	penicillin binding
C6M02_RS14005	COG2226	methyltransferase
C6M02_RS14020	COG3716	PTS system mannose fructose sorbose family IID component
C6M02_RS14025	COG3715	PTS system
C6M02_RS14030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6M02_RS14030	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS14035	COG1253	flavin adenine dinucleotide binding
C6M02_RS14040	COG2200	EAL domain
C6M02_RS14045	COG1760	l-serine dehydratase
C6M02_RS14065	COG0251	oxidation-reduction process
C6M02_RS14070	COG1199	ATP-dependent helicase activity
C6M02_RS14080	COG3065	identical protein binding
C6M02_RS14090	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C6M02_RS14100	COG2894	cell division
C6M02_RS14115	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6M02_RS14145	COG2719	SpoVR family
C6M02_RS14165	COG1619	proteins homologs of microcin C7 resistance protein MccF
C6M02_RS14175	COG4774	siderophore transport
C6M02_RS14190	COG2308	Evidence 4 Homologs of previously reported genes of
C6M02_RS14230	COG0583	DNA-binding transcription factor activity
C6M02_RS14235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6M02_RS14250	COG1882	Formate acetyltransferase
C6M02_RS14280	COG0583	DNA-binding transcription factor activity
C6M02_RS14325	COG0583	DNA-binding transcription factor activity
C6M02_RS14340	COG3122	Protein conserved in bacteria
C6M02_RS14370	COG2885	chlorophyll binding
C6M02_RS14440	COG0012	GTP binding
C6M02_RS14460	COG0659	secondary active sulfate transmembrane transporter activity
C6M02_RS14495	COG2890	protein-(glutamine-N5) methyltransferase activity
C6M02_RS14515	COG0387	Pfam Sodium calcium exchanger
C6M02_RS14520	COG4572	Cation transport regulator
C6M02_RS14525	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C6M02_RS14535	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C6M02_RS14540	COG3707	response regulator
C6M02_RS14545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6M02_RS14555	COG1116	anion transmembrane transporter activity
C6M02_RS14560	COG2146	nitrite reductase [NAD(P)H] activity
C6M02_RS14560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6M02_RS14565	COG0243	molybdopterin cofactor binding
C6M02_RS14570	COG4932	domain protein
C6M02_RS14575	COG2197	response regulator
C6M02_RS14580	COG3850	Histidine kinase
C6M02_RS14585	COG2223	nitrite transmembrane transporter activity
C6M02_RS14590	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6M02_RS14595	COG1140	nitrate reductase beta subunit
C6M02_RS14600	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6M02_RS14605	COG2181	nitrate reductase activity
C6M02_RS14615	COG1522	sequence-specific DNA binding
C6M02_RS14650	COG0788	formyltetrahydrofolate deformylase activity
C6M02_RS14660	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6M02_RS14665	COG0745	RESPONSE REGULATOR receiver
C6M02_RS14670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6M02_RS14675	COG2916	Histone family protein nucleoid-structuring protein H-NS
C6M02_RS14680	COG1435	thymidine kinase activity
C6M02_RS14685	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS14685	COG1454	alcohol dehydrogenase
C6M02_RS14695	COG2095	MarC family integral membrane protein
C6M02_RS14700	COG4166	transmembrane transport
C6M02_RS14705	COG0601	transmembrane transport
C6M02_RS14710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6M02_RS14715	COG0444	Belongs to the ABC transporter superfamily
C6M02_RS14725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6M02_RS14745	COG2353	YceI-like domain
C6M02_RS14750	COG2350	Protein conserved in bacteria
C6M02_RS14760	COG3001	Fructosamine kinase
C6M02_RS14770	COG1105	Belongs to the carbohydrate kinase PfkB family
C6M02_RS14775	COG3137	Salt-induced outer membrane protein
C6M02_RS14815	COG0072	phenylalanine-tRNA ligase activity
C6M02_RS14815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6M02_RS14835	COG0583	DNA-binding transcription factor activity
C6M02_RS14855	COG0386	Belongs to the glutathione peroxidase family
C6M02_RS14865	COG0791	NLP P60 protein
C6M02_RS14875	COG4256	Hemin uptake protein
C6M02_RS14880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6M02_RS14890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6M02_RS14890	COG0574	Belongs to the PEP-utilizing enzyme family
C6M02_RS14900	COG0628	permease
C6M02_RS14905	COG0247	lactate metabolic process
C6M02_RS14905	COG0277	FAD linked oxidase domain protein
C6M02_RS14910	COG2050	protein possibly involved in aromatic compounds catabolism
C6M02_RS14915	COG2261	transglycosylase associated protein
C6M02_RS14945	COG1120	ATPase activity
C6M02_RS14950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6M02_RS14960	COG0583	DNA-binding transcription factor activity
C6M02_RS14985	COG1304	FMN binding
C6M02_RS14990	COG1309	transcriptional regulator
C6M02_RS15005	COG0316	Belongs to the HesB IscA family
C6M02_RS15010	COG0719	Fe-S assembly protein
C6M02_RS15015	COG0396	ATPase activity
C6M02_RS15020	COG0719	Fe-S assembly protein
C6M02_RS15035	COG1376	ErfK ybiS ycfS ynhG family protein
C6M02_RS15060	COG1309	transcriptional regulator
C6M02_RS15065	COG1082	Xylose isomerase domain protein TIM barrel
C6M02_RS15065	COG3185	4-Hydroxyphenylpyruvate dioxygenase
C6M02_RS15070	COG2271	Major facilitator Superfamily
C6M02_RS15075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C6M02_RS15085	COG1120	ATPase activity
C6M02_RS15090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6M02_RS15095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6M02_RS15100	COG1414	Transcriptional regulator
C6M02_RS15135	COG2814	Major facilitator Superfamily
C6M02_RS15155	COG0583	DNA-binding transcription factor activity
C6M02_RS15160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6M02_RS15180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6M02_RS15185	COG1116	anion transmembrane transporter activity
C6M02_RS15190	COG4774	siderophore transport
C6M02_RS15195	COG1120	ATPase activity
C6M02_RS15200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6M02_RS15205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6M02_RS15225	COG0765	amino acid transport
C6M02_RS15230	COG1126	abc transporter atp-binding protein
C6M02_RS15260	COG1473	amidohydrolase
C6M02_RS15265	COG3383	formate dehydrogenase (NAD+) activity
C6M02_RS15270	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C6M02_RS15285	COG1175	transmembrane transport
C6M02_RS15315	COG4133	protoheme IX ABC transporter activity
C6M02_RS15320	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6M02_RS15325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6M02_RS15340	COG1138	Cytochrome C-type biogenesis protein
C6M02_RS15345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6M02_RS15350	COG4235	cytochrome complex assembly
C6M02_RS15350	COG3088	subunit of a heme lyase
C6M02_RS15390	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C6M02_RS15435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6M02_RS15470	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS15475	COG2610	gluconate transmembrane transporter activity
C6M02_RS15480	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6M02_RS15490	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6M02_RS15500	COG0583	DNA-binding transcription factor activity
C6M02_RS15525	COG0277	FAD linked oxidase domain protein
C6M02_RS15530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6M02_RS15555	COG0402	S-adenosylhomocysteine deaminase activity
C6M02_RS15605	COG3321	synthase
C6M02_RS15605	COG0604	alcohol dehydrogenase
C6M02_RS15605	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS15635	COG4608	Belongs to the ABC transporter superfamily
C6M02_RS15640	COG0444	Belongs to the ABC transporter superfamily
C6M02_RS15665	COG0346	lactoylglutathione lyase activity
C6M02_RS15670	COG1349	DNA-binding transcription factor activity
C6M02_RS15700	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C6M02_RS15755	COG0307	riboflavin synthase, alpha
C6M02_RS15760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C6M02_RS15765	COG2814	Major facilitator Superfamily
C6M02_RS15770	COG0583	DNA-binding transcription factor activity
C6M02_RS15785	COG2814	Major facilitator Superfamily
C6M02_RS15800	COG0791	NLP P60 protein
C6M02_RS15805	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C6M02_RS15815	COG0346	lactoylglutathione lyase activity
C6M02_RS15820	COG1902	pentaerythritol trinitrate reductase activity
C6M02_RS15825	COG1309	transcriptional regulator
C6M02_RS15830	COG3313	Fe-S protein
C6M02_RS15835	COG4989	oxidoreductase activity
C6M02_RS15840	COG2032	superoxide dismutase activity
C6M02_RS15845	COG1289	transmembrane transporter activity
C6M02_RS15850	COG1566	PFAM secretion protein HlyD family protein
C6M02_RS15865	COG3706	GGDEF domain
C6M02_RS15880	COG3895	Periplasmic Protein
C6M02_RS15895	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C6M02_RS15900	COG0625	glutathione transferase activity
C6M02_RS15915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C6M02_RS15925	COG4659	FMN binding
C6M02_RS15960	COG2723	6-phospho-beta-galactosidase activity
C6M02_RS15970	COG0673	inositol 2-dehydrogenase activity
C6M02_RS15980	COG2814	Major facilitator Superfamily
C6M02_RS16000	COG3038	cytochrome b561
C6M02_RS16020	COG0583	DNA-binding transcription factor activity
C6M02_RS16025	COG3485	protocatechuate 3,4-dioxygenase
C6M02_RS16030	COG3485	protocatechuate 3,4-dioxygenase
C6M02_RS16035	COG5383	Protein conserved in bacteria
C6M02_RS16040	COG2272	Belongs to the type-B carboxylesterase lipase family
C6M02_RS16055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6M02_RS16060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6M02_RS16065	COG1275	C4-dicarboxylate transporter malic acid transport protein
C6M02_RS16070	COG0500	methyltransferase
C6M02_RS16085	COG2207	Transcriptional regulator
C6M02_RS16085	COG3708	Transcriptional regulator
C6M02_RS16090	COG3135	benzoate transporter
C6M02_RS16095	COG1396	sequence-specific DNA binding
C6M02_RS16105	COG0826	peptidase U32
C6M02_RS16125	COG1294	oxidase, subunit
C6M02_RS16130	COG1271	oxidase subunit
C6M02_RS16135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6M02_RS16140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6M02_RS16145	COG3842	ATPase activity
C6M02_RS16150	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6M02_RS16155	COG1177	transmembrane transport
C6M02_RS16160	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS16190	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS16195	COG0747	negative chemotaxis
C6M02_RS16205	COG3238	Protein conserved in bacteria
C6M02_RS16210	COG1247	-acetyltransferase
C6M02_RS16220	COG2130	NADP-dependent
C6M02_RS16235	COG3691	Protein conserved in bacteria
C6M02_RS16240	COG1228	amidohydrolase
C6M02_RS16245	COG4772	TonB-dependent receptor
C6M02_RS16270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C6M02_RS16275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6M02_RS16280	COG1473	amidohydrolase
C6M02_RS16285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6M02_RS16290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6M02_RS16300	COG0765	amino acid transport
C6M02_RS16305	COG1126	abc transporter atp-binding protein
C6M02_RS16315	COG0625	glutathione transferase activity
C6M02_RS16345	COG2211	Major facilitator Superfamily
C6M02_RS16360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6M02_RS16365	COG3842	ATPase activity
C6M02_RS16370	COG1840	ABC-type Fe3 transport system, periplasmic component
C6M02_RS16375	COG1178	ABC-type Fe3 transport system permease component
C6M02_RS16380	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C6M02_RS16385	COG2181	nitrate reductase activity
C6M02_RS16390	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6M02_RS16395	COG1140	nitrate reductase beta subunit
C6M02_RS16400	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6M02_RS16420	COG1414	Transcriptional regulator
C6M02_RS16425	COG4948	Mandelate Racemase Muconate Lactonizing
C6M02_RS16430	COG4829	muconolactone delta-isomerase
C6M02_RS16435	COG3485	protocatechuate 3,4-dioxygenase
C6M02_RS16445	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C6M02_RS16465	COG3383	formate dehydrogenase (NAD+) activity
C6M02_RS16465	COG0243	molybdopterin cofactor binding
C6M02_RS16470	COG3383	formate dehydrogenase (NAD+) activity
C6M02_RS16470	COG0243	molybdopterin cofactor binding
C6M02_RS16475	COG0437	4 iron, 4 sulfur cluster binding
C6M02_RS16480	COG2864	formate dehydrogenase
C6M02_RS16495	COG2326	polyphosphate kinase activity
C6M02_RS16505	COG2814	Major facilitator Superfamily
C6M02_RS16515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6M02_RS16525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6M02_RS16535	COG0747	negative chemotaxis
C6M02_RS16540	COG1064	alcohol dehydrogenase
C6M02_RS16555	COG0488	(ABC) transporter
C6M02_RS16595	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS16600	COG3729	General stress protein
C6M02_RS16615	COG3685	Protein conserved in bacteria
C6M02_RS16625	COG0366	Alpha amylase catalytic
C6M02_RS16635	COG2323	membrane
C6M02_RS16645	COG3111	PFAM Bacterial OB fold (BOF) protein
C6M02_RS16650	COG1764	response to oxidative stress
C6M02_RS16675	COG3781	membrane
C6M02_RS16680	COG0243	molybdopterin cofactor binding
C6M02_RS16685	COG0583	DNA-binding transcription factor activity
C6M02_RS16690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS16715	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS16720	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6M02_RS16725	COG2814	Major facilitator Superfamily
C6M02_RS16735	COG1285	pathogenesis
C6M02_RS16740	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C6M02_RS16750	COG0583	DNA-binding transcription factor activity
C6M02_RS16770	COG0519	Catalyzes the synthesis of GMP from XMP
C6M02_RS16770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C6M02_RS16810	COG0596	Alpha beta hydrolase
C6M02_RS16820	COG2205	protein histidine kinase activity
C6M02_RS16835	COG0076	glutamate decarboxylase activity
C6M02_RS16840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6M02_RS16845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6M02_RS16850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6M02_RS16855	COG1116	anion transmembrane transporter activity
C6M02_RS16860	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C6M02_RS16870	COG0673	inositol 2-dehydrogenase activity
C6M02_RS16880	COG1609	Transcriptional regulator
C6M02_RS16885	COG3706	GGDEF domain
C6M02_RS16890	COG0402	S-adenosylhomocysteine deaminase activity
C6M02_RS16895	COG1953	Uracil, thiamine, allantoin
C6M02_RS16930	COG0406	alpha-ribazole phosphatase activity
C6M02_RS16940	COG1335	isochorismatase
C6M02_RS16980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6M02_RS17045	COG0765	amino acid transport
C6M02_RS17055	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C6M02_RS17065	COG2070	2-Nitropropane dioxygenase
C6M02_RS17070	COG0583	DNA-binding transcription factor activity
C6M02_RS17080	COG1902	pentaerythritol trinitrate reductase activity
C6M02_RS17085	COG4529	Protein conserved in bacteria
C6M02_RS17090	COG0477	Major facilitator Superfamily
C6M02_RS17120	COG2223	nitrite transmembrane transporter activity
C6M02_RS17130	COG1609	Transcriptional regulator
C6M02_RS17135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS17155	COG3037	sugar-specific permease SgaT UlaA
C6M02_RS17160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6M02_RS17170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6M02_RS17175	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C6M02_RS17175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6M02_RS17175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6M02_RS17190	COG0583	DNA-binding transcription factor activity
C6M02_RS17195	COG0583	DNA-binding transcription factor activity
C6M02_RS17200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6M02_RS17210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6M02_RS17225	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS17235	COG1609	Transcriptional regulator
C6M02_RS17265	COG1652	LysM domain
C6M02_RS17280	COG0426	domain, Protein
C6M02_RS17280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6M02_RS17310	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C6M02_RS17310	COG0456	acetyltransferase
C6M02_RS17320	COG0667	Aldo Keto reductase
C6M02_RS17325	COG0667	Aldo Keto reductase
C6M02_RS17335	COG0667	Aldo Keto reductase
C6M02_RS17350	COG4977	sequence-specific DNA binding
C6M02_RS17370	COG4977	sequence-specific DNA binding
C6M02_RS17375	COG1349	DNA-binding transcription factor activity
C6M02_RS17390	COG1349	DNA-binding transcription factor activity
C6M02_RS17395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6M02_RS17400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6M02_RS17405	COG0738	Major facilitator superfamily
C6M02_RS17450	COG1929	Belongs to the glycerate kinase type-1 family
C6M02_RS17455	COG3835	regulator
C6M02_RS17475	COG2186	Transcriptional regulator
C6M02_RS17480	COG1263	PTS System
C6M02_RS17480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6M02_RS17495	COG2814	Major facilitator Superfamily
C6M02_RS17500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS17500	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS17515	COG2819	hydrolase of the alpha beta superfamily
C6M02_RS17520	COG5001	Diguanylate cyclase
C6M02_RS17520	COG3300	MHYT domain
C6M02_RS17555	COG3188	usher protein
C6M02_RS17565	COG1649	PFAM Uncharacterised BCR, COG1649
C6M02_RS17570	COG3550	peptidyl-serine autophosphorylation
C6M02_RS17575	COG1396	sequence-specific DNA binding
C6M02_RS17580	COG2351	hydroxyisourate hydrolase activity
C6M02_RS17585	COG3195	allantoin biosynthetic process
C6M02_RS17585	COG3648	Uricase
C6M02_RS17590	COG2233	PERMEase
C6M02_RS17620	COG2207	Transcriptional regulator
C6M02_RS17635	COG4628	conserved protein (DUF2132)
C6M02_RS17655	COG2011	ABC-type metal ion transport system permease component
C6M02_RS17660	COG2070	2-Nitropropane dioxygenase
C6M02_RS17670	COG0477	Major facilitator Superfamily
C6M02_RS17750	COG2199	diguanylate cyclase activity
C6M02_RS17765	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS17770	COG0583	DNA-binding transcription factor activity
C6M02_RS17780	COG0039	L-malate dehydrogenase activity
C6M02_RS17785	COG1349	DNA-binding transcription factor activity
C6M02_RS17790	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C6M02_RS17795	COG3395	kinase activity
C6M02_RS17805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C6M02_RS17820	COG2731	YhcH YjgK YiaL family protein
C6M02_RS17825	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS17850	COG4977	sequence-specific DNA binding
C6M02_RS17860	COG0697	spore germination
C6M02_RS17865	COG2814	Major facilitator Superfamily
C6M02_RS17875	COG0410	ABC transporter
C6M02_RS17880	COG1129	ABC transporter
C6M02_RS17895	COG0683	leucine binding
C6M02_RS17900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C6M02_RS17935	COG2223	nitrite transmembrane transporter activity
C6M02_RS17940	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C6M02_RS17955	COG1349	DNA-binding transcription factor activity
C6M02_RS17960	COG2084	Dehydrogenase
C6M02_RS17965	COG3395	kinase activity
C6M02_RS17970	COG0235	Class ii aldolase
C6M02_RS17975	COG3622	Belongs to the hyi family
C6M02_RS17980	COG2610	gluconate transmembrane transporter activity
C6M02_RS17985	COG3708	Transcriptional regulator
C6M02_RS17985	COG2207	Transcriptional regulator
C6M02_RS18020	COG2200	EAL domain
C6M02_RS18025	COG1546	Belongs to the CinA family
C6M02_RS18030	COG0071	Belongs to the small heat shock protein (HSP20) family
C6M02_RS18040	COG2197	response regulator
C6M02_RS18045	COG2135	peptidase activity
C6M02_RS18050	COG2207	Transcriptional regulator
C6M02_RS18065	COG4221	oxidoreductase activity
C6M02_RS18070	COG1802	Transcriptional regulator
C6M02_RS18075	COG0589	response to stress
C6M02_RS18080	COG0246	Mannitol dehydrogenase
C6M02_RS18085	COG2271	Major facilitator Superfamily
C6M02_RS18100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6M02_RS18130	COG0437	4 iron, 4 sulfur cluster binding
C6M02_RS18135	COG3302	dmso reductase anchor subunit
C6M02_RS18150	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C6M02_RS18155	COG1940	carbohydrate kinase activity
C6M02_RS18160	COG0583	DNA-binding transcription factor activity
C6M02_RS18165	COG2814	Major facilitator Superfamily
C6M02_RS18170	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C6M02_RS18180	COG3591	Belongs to the peptidase S1B family
C6M02_RS18200	COG0628	permease
C6M02_RS18230	COG0679	Auxin Efflux Carrier
C6M02_RS18240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6M02_RS18265	COG3290	protein histidine kinase activity
C6M02_RS18270	COG4565	transcriptional regulatory protein
C6M02_RS18295	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6M02_RS18295	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6M02_RS18315	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6M02_RS18320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6M02_RS18330	COG0183	Belongs to the thiolase family
C6M02_RS18335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6M02_RS18345	COG1414	Transcriptional regulator
C6M02_RS18350	COG2840	Smr protein MutS2
C6M02_RS18355	COG0583	DNA-binding transcription factor activity
C6M02_RS18365	COG1473	amidohydrolase
C6M02_RS18370	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C6M02_RS18385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6M02_RS18400	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C6M02_RS18405	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C6M02_RS18425	COG0531	amino acid
C6M02_RS18435	COG3136	membrane protein required for alginate biosynthesis
C6M02_RS18440	COG0745	RESPONSE REGULATOR receiver
C6M02_RS18450	COG2205	protein histidine kinase activity
C6M02_RS18460	COG0114	fumarate hydratase activity
C6M02_RS18465	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C6M02_RS18465	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C6M02_RS18470	COG1482	cell wall glycoprotein biosynthetic process
C6M02_RS18475	COG5339	Protein conserved in bacteria
C6M02_RS18480	COG1609	Transcriptional regulator
C6M02_RS18485	COG1263	PTS System
C6M02_RS18485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6M02_RS18490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C6M02_RS18515	COG2391	methyltransferase activity
C6M02_RS18520	COG0425	Belongs to the sulfur carrier protein TusA family
C6M02_RS18525	COG5562	phage envelope protein
C6M02_RS18530	COG0401	homolog of Blt101
C6M02_RS18535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6M02_RS18540	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS18545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6M02_RS18550	COG0477	Major facilitator Superfamily
C6M02_RS18555	COG1113	amino acid transport
C6M02_RS18560	COG2988	succinylglutamate desuccinylase activity
C6M02_RS18565	COG3724	N-succinylarginine dihydrolase activity
C6M02_RS18570	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS18575	COG3138	arginine N-succinyltransferase
C6M02_RS18580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6M02_RS18585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6M02_RS18590	COG0667	Aldo Keto reductase
C6M02_RS18595	COG0583	DNA-binding transcription factor activity
C6M02_RS18620	COG4122	O-methyltransferase activity
C6M02_RS18625	COG1643	Atp-dependent helicase
C6M02_RS18640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6M02_RS18645	COG3327	negative regulation of DNA-templated transcription, initiation
C6M02_RS18650	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C6M02_RS18655	COG0183	Belongs to the thiolase family
C6M02_RS18660	COG2050	protein possibly involved in aromatic compounds catabolism
C6M02_RS18665	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6M02_RS18670	COG1024	Enoyl-CoA hydratase
C6M02_RS18675	COG1024	Enoyl-CoA hydratase
C6M02_RS18680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6M02_RS18685	COG2151	metal-sulfur cluster biosynthetic enzyme
C6M02_RS18690	COG3396	Phenylacetate-CoA oxygenase
C6M02_RS18695	COG3460	Phenylacetate-CoA oxygenase
C6M02_RS18700	COG3396	Phenylacetate-CoA oxygenase
C6M02_RS18705	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS18705	COG2030	dehydratase
C6M02_RS18735	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS18740	COG2207	Transcriptional regulator
C6M02_RS18745	COG3784	Protein of unknown function (DUF1318)
C6M02_RS18755	COG2911	Protein conserved in bacteria
C6M02_RS18760	COG0586	Pfam SNARE associated Golgi protein
C6M02_RS18765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C6M02_RS18770	COG3187	Heat shock protein
C6M02_RS18775	COG3042	response to heat
C6M02_RS18785	COG1013	pyruvate-flavodoxin oxidoreductase activity
C6M02_RS18785	COG0674	pyruvate-flavodoxin oxidoreductase activity
C6M02_RS18785	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C6M02_RS18785	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6M02_RS18790	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C6M02_RS18800	COG0589	response to stress
C6M02_RS18810	COG0513	Belongs to the DEAD box helicase family
C6M02_RS18830	COG1349	DNA-binding transcription factor activity
C6M02_RS18835	COG0673	inositol 2-dehydrogenase activity
C6M02_RS18850	COG1113	amino acid transport
C6M02_RS18855	COG1522	sequence-specific DNA binding
C6M02_RS18865	COG1448	Aminotransferase
C6M02_RS18870	COG2011	ABC-type metal ion transport system permease component
C6M02_RS18885	COG0436	Aminotransferase
C6M02_RS18890	COG0604	alcohol dehydrogenase
C6M02_RS18915	COG0583	DNA-binding transcription factor activity
C6M02_RS18935	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS18940	COG1309	transcriptional regulator
C6M02_RS18945	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS19040	COG2885	chlorophyll binding
C6M02_RS19170	COG1196	nuclear chromosome segregation
C6M02_RS19170	COG0741	lytic transglycosylase activity
C6M02_RS19170	COG0739	heme binding
C6M02_RS19240	COG3567	Phage-associated protein, HI1409 family
C6M02_RS19245	COG1783	phage Terminase large subunit
C6M02_RS19265	COG3772	lysozyme
C6M02_RS19275	COG0484	heat shock protein binding
C6M02_RS19375	COG0582	viral genome integration into host DNA
C6M02_RS19380	COG0693	protein deglycase activity
C6M02_RS19385	COG1078	dGTPase activity
C6M02_RS19390	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS19395	COG0583	DNA-binding transcription factor activity
C6M02_RS19415	COG0656	L-ascorbic acid biosynthetic process
C6M02_RS19445	COG4166	transmembrane transport
C6M02_RS19450	COG2866	Carboxypeptidase
C6M02_RS19455	COG4948	Mandelate Racemase Muconate Lactonizing
C6M02_RS19460	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C6M02_RS19465	COG3180	Ammonia monooxygenase
C6M02_RS19475	COG1486	melibiose metabolic process
C6M02_RS19480	COG0583	DNA-binding transcription factor activity
C6M02_RS19490	COG3106	COG3106 Predicted ATPase
C6M02_RS19500	COG1983	PspC domain protein
C6M02_RS19510	COG1842	Phage shock protein A
C6M02_RS19515	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C6M02_RS19525	COG1473	amidohydrolase
C6M02_RS19540	COG0702	epimerase
C6M02_RS19555	COG4171	peptide transport system, permease
C6M02_RS19570	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C6M02_RS19580	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C6M02_RS19585	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6M02_RS19585	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6M02_RS19600	COG1349	DNA-binding transcription factor activity
C6M02_RS19610	COG0023	Translation Initiation Factor
C6M02_RS19620	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C6M02_RS19625	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C6M02_RS19630	COG0671	phosphoesterase, PA-phosphatase related
C6M02_RS19640	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6M02_RS19670	COG0616	signal peptide processing
C6M02_RS19680	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS19685	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C6M02_RS19695	COG0583	DNA-binding transcription factor activity
C6M02_RS19705	COG0009	L-threonylcarbamoyladenylate synthase
C6M02_RS19715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6M02_RS19720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6M02_RS19720	COG0512	Glutamine amidotransferase of anthranilate synthase
C6M02_RS19725	COG0134	indole-3-glycerol-phosphate synthase activity
C6M02_RS19725	COG0135	phosphoribosylanthranilate isomerase activity
C6M02_RS19780	COG4774	siderophore transport
C6M02_RS19790	COG3047	cAMP biosynthetic process
C6M02_RS19795	COG0727	PFAM Uncharacterised protein family (UPF0153)
C6M02_RS19825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6M02_RS19830	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS19835	COG1988	membrane-bound metal-dependent
C6M02_RS19840	COG1823	symporter activity
C6M02_RS19850	COG0753	catalase activity
C6M02_RS19875	COG1917	Cupin 2, conserved barrel domain protein
C6M02_RS19875	COG2169	Transcriptional regulator
C6M02_RS19880	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6M02_RS19885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS19890	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS19895	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6M02_RS19905	COG0322	excinuclease ABC activity
C6M02_RS19910	COG3678	ATP-independent chaperone mediated protein folding
C6M02_RS19920	COG3724	N-succinylarginine dihydrolase activity
C6M02_RS19930	COG3138	arginine N-succinyltransferase
C6M02_RS19940	COG0708	Exodeoxyribonuclease III
C6M02_RS19945	COG0398	Pfam SNARE associated Golgi protein
C6M02_RS19950	COG0398	Pfam SNARE associated Golgi protein
C6M02_RS19955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6M02_RS19960	COG4134	Bacterial extracellular solute-binding protein
C6M02_RS19965	COG4135	transport system, permease component
C6M02_RS19970	COG4136	ATPase activity
C6M02_RS19975	COG2897	thiosulfate sulfurtransferase activity
C6M02_RS19980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6M02_RS19985	COG0494	nUDIX hydrolase
C6M02_RS19990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6M02_RS19995	COG3321	synthase
C6M02_RS19995	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS19995	COG0604	alcohol dehydrogenase
C6M02_RS20000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6M02_RS20005	COG0709	Synthesizes selenophosphate from selenide and ATP
C6M02_RS20025	COG0778	Nitroreductase
C6M02_RS20030	COG0616	signal peptide processing
C6M02_RS20035	COG0252	asparaginase activity
C6M02_RS20040	COG1335	isochorismatase
C6M02_RS20045	COG2814	Major facilitator Superfamily
C6M02_RS20050	COG1349	DNA-binding transcription factor activity
C6M02_RS20055	COG0667	Aldo Keto reductase
C6M02_RS20060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6M02_RS20065	COG0191	fructose-bisphosphate aldolase activity
C6M02_RS20070	COG1063	alcohol dehydrogenase
C6M02_RS20075	COG2271	Major facilitator Superfamily
C6M02_RS20080	COG1063	alcohol dehydrogenase
C6M02_RS20095	COG3139	Protein of unknown function (DUF1315)
C6M02_RS20120	COG3713	MltA-interacting MipA family protein
C6M02_RS20125	COG2766	serine protein kinase
C6M02_RS20140	COG0386	Belongs to the glutathione peroxidase family
C6M02_RS20160	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS20165	COG0583	DNA-binding transcription factor activity
C6M02_RS20170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6M02_RS20175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6M02_RS20180	COG3344	reverse transcriptase
C6M02_RS20195	COG0859	PFAM glycosyl transferase family 9
C6M02_RS20200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6M02_RS20210	COG2207	Transcriptional regulator
C6M02_RS20215	COG2807	transmembrane transport
C6M02_RS20220	COG0504	CTP synthase activity
C6M02_RS20225	COG1683	Conserved Protein
C6M02_RS20230	COG3189	MarR family transcriptional regulator
C6M02_RS20235	COG3042	response to heat
C6M02_RS20240	COG2199	diguanylate cyclase activity
C6M02_RS20240	COG2203	Gaf domain
C6M02_RS20260	COG3182	Iron-regulated membrane protein
C6M02_RS20270	COG1560	Kdo2-lipid A biosynthetic process
C6M02_RS20285	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C6M02_RS20290	COG3706	GGDEF domain
C6M02_RS20295	COG0583	DNA-binding transcription factor activity
C6M02_RS20300	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C6M02_RS20325	COG1294	oxidase, subunit
C6M02_RS20330	COG1271	oxidase subunit
C6M02_RS20335	COG3546	catalase activity
C6M02_RS20340	COG3685	Protein conserved in bacteria
C6M02_RS20345	COG3685	Protein conserved in bacteria
C6M02_RS20350	COG3729	General stress protein
C6M02_RS20355	COG1063	alcohol dehydrogenase
C6M02_RS20360	COG3813	Protein conserved in bacteria
C6M02_RS20375	COG0640	Transcriptional regulator
C6M02_RS20380	COG0538	isocitrate dehydrogenase activity
C6M02_RS20385	COG1187	pseudouridine synthase activity
C6M02_RS20405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C6M02_RS20425	COG2205	protein histidine kinase activity
C6M02_RS20430	COG2850	peptidyl-arginine hydroxylation
C6M02_RS20450	COG1177	transmembrane transport
C6M02_RS20465	COG0318	PFAM AMP-dependent synthetase and ligase
C6M02_RS20475	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C6M02_RS20485	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6M02_RS20495	COG4591	ABC-type transport system involved in lipoprotein release permease component
C6M02_RS20505	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C6M02_RS20510	COG1388	LysM domain
C6M02_RS20510	COG1376	ErfK ybiS ycfS ynhG family protein
C6M02_RS20520	COG1309	transcriptional regulator
C6M02_RS20530	COG3134	Outer membrane lipoprotein
C6M02_RS20535	COG1252	NADH dehydrogenase
C6M02_RS20560	COG5633	Lipoprotein
C6M02_RS20565	COG0537	adenosine 5'-monophosphoramidase activity
C6M02_RS20575	COG0084	hydrolase, TatD family'
C6M02_RS20580	COG0470	DNA polymerase III
C6M02_RS20590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6M02_RS20595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6M02_RS20600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6M02_RS20615	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6M02_RS20635	COG1399	metal-binding, possibly nucleic acid-binding protein
C6M02_RS20655	COG1530	ribonuclease E activity
C6M02_RS20660	COG0583	DNA-binding transcription factor activity
C6M02_RS20665	COG2814	Major facilitator Superfamily
C6M02_RS20685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6M02_RS20735	COG1560	Kdo2-lipid A biosynthetic process
C6M02_RS20755	COG5645	(Lipo)protein
C6M02_RS20795	COG3381	protein complex oligomerization
C6M02_RS20820	COG0583	DNA-binding transcription factor activity
C6M02_RS20830	COG1335	isochorismatase
C6M02_RS20840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6M02_RS20845	COG1702	phosphate starvation-inducible protein PhoH
C6M02_RS20865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6M02_RS20875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6M02_RS20895	COG1309	transcriptional regulator
C6M02_RS20930	COG2233	PERMEase
C6M02_RS20940	COG3729	General stress protein
C6M02_RS20965	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS20980	COG0531	amino acid
C6M02_RS20990	COG0174	glutamine synthetase
C6M02_RS20995	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C6M02_RS21000	COG1917	Cupin 2, conserved barrel domain protein
C6M02_RS21000	COG1396	sequence-specific DNA binding
C6M02_RS21005	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS21010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6M02_RS21015	COG0583	DNA-binding transcription factor activity
C6M02_RS21020	COG0473	3-isopropylmalate dehydrogenase activity
C6M02_RS21030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6M02_RS21035	COG4638	Rieske (2fe-2S)
C6M02_RS21040	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS21045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6M02_RS21055	COG2200	EAL domain
C6M02_RS21060	COG2200	EAL domain
C6M02_RS21075	COG0670	Belongs to the BI1 family
C6M02_RS21090	COG2207	Transcriptional regulator
C6M02_RS21095	COG1881	PFAM PEBP family protein
C6M02_RS21110	COG1832	CoA-binding protein
C6M02_RS21120	COG0210	DNA helicase
C6M02_RS21125	COG3304	Inner membrane component domain
C6M02_RS21130	COG1289	transmembrane transporter activity
C6M02_RS21135	COG3070	regulator of competence-specific genes
C6M02_RS21160	COG1067	ATP-dependent peptidase activity
C6M02_RS21170	COG3130	regulation of translation
C6M02_RS21180	COG3009	Protein conserved in bacteria
C6M02_RS21185	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C6M02_RS21185	COG3008	intermembrane lipid transfer
C6M02_RS21190	COG2995	paraquat-inducible protein a
C6M02_RS21195	COG0488	(ABC) transporter
C6M02_RS21205	COG3217	Mosc domain protein beta barrel domain protein
C6M02_RS21205	COG0633	Ferredoxin
C6M02_RS21220	COG0431	NADPH-dependent FMN reductase
C6M02_RS21225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6M02_RS21230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6M02_RS21235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6M02_RS21245	COG0308	aminopeptidase N
C6M02_RS21260	COG1473	amidohydrolase
C6M02_RS21270	COG0814	amino acid
C6M02_RS21280	COG1522	sequence-specific DNA binding
C6M02_RS21295	COG1448	Aminotransferase
C6M02_RS21300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6M02_RS21305	COG3108	Peptidase M15
C6M02_RS21315	COG2989	Protein conserved in bacteria
C6M02_RS21325	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C6M02_RS21335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C6M02_RS21340	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6M02_RS21345	COG3173	Aminoglycoside phosphotransferase
C6M02_RS21360	COG3214	Protein conserved in bacteria
C6M02_RS21375	COG2333	competence protein COMEC
C6M02_RS21375	COG0658	competence protein
C6M02_RS21385	COG0539	negative regulation of cytoplasmic translation
C6M02_RS21405	COG2323	membrane
C6M02_RS21410	COG1944	ATP diphosphatase activity
C6M02_RS21415	COG2116	formate transmembrane transporter activity
C6M02_RS21420	COG1882	Formate acetyltransferase
C6M02_RS21425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6M02_RS21430	COG0477	Major facilitator Superfamily
C6M02_RS21440	COG3302	dmso reductase anchor subunit
C6M02_RS21445	COG0437	4 iron, 4 sulfur cluster binding
C6M02_RS21450	COG0243	molybdopterin cofactor binding
C6M02_RS21460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C6M02_RS21470	COG1674	ftsk spoiiie
C6M02_RS21470	COG1178	ABC-type Fe3 transport system permease component
C6M02_RS21480	COG0492	ferredoxin-NADP+ reductase activity
C6M02_RS21485	COG4988	ABC transporter
C6M02_RS21490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C6M02_RS21505	COG0542	response to heat
C6M02_RS21515	COG1278	Cold shock
C6M02_RS21530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6M02_RS21535	COG3593	DNA synthesis involved in DNA repair
C6M02_RS21545	COG2431	L-lysine efflux transmembrane transporter activity
C6M02_RS21555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6M02_RS21570	COG0028	Belongs to the TPP enzyme family
C6M02_RS21575	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C6M02_RS21580	COG0702	epimerase
C6M02_RS21585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6M02_RS21590	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6M02_RS21595	COG2203	Gaf domain
C6M02_RS21595	COG3706	GGDEF domain
C6M02_RS21595	COG5001	Diguanylate cyclase
C6M02_RS21595	COG4251	negative regulation of phosphorylation
C6M02_RS21610	COG1126	abc transporter atp-binding protein
C6M02_RS21615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6M02_RS21620	COG4215	(ABC) transporter
C6M02_RS21625	COG4160	amino acid transport
C6M02_RS21630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6M02_RS21635	COG5002	protein histidine kinase activity
C6M02_RS21640	COG0745	RESPONSE REGULATOR receiver
C6M02_RS21655	COG1177	transmembrane transport
C6M02_RS21660	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6M02_RS21665	COG3842	ATPase activity
C6M02_RS21670	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6M02_RS21855	COG4695	Portal protein
C6M02_RS21880	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C6M02_RS21885	COG3226	Transcriptional regulator
C6M02_RS21890	COG0738	Major facilitator superfamily
C6M02_RS21895	COG0561	phosphatase activity
C6M02_RS21900	COG2814	Major facilitator Superfamily
C6M02_RS21910	COG0671	phosphoesterase, PA-phosphatase related
C6M02_RS21915	COG1349	DNA-binding transcription factor activity
C6M02_RS21920	COG1686	Belongs to the peptidase S11 family
C6M02_RS21925	COG0625	glutathione transferase activity
C6M02_RS21930	COG2133	pyrroloquinoline quinone binding
C6M02_RS21940	COG2223	nitrite transmembrane transporter activity
C6M02_RS21965	COG0747	negative chemotaxis
C6M02_RS21980	COG0303	'Molybdopterin
C6M02_RS21985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6M02_RS21990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6M02_RS21995	COG1882	Formate acetyltransferase
C6M02_RS22000	COG0561	phosphatase activity
C6M02_RS22010	COG1609	Transcriptional regulator
C6M02_RS22015	COG2271	Major facilitator Superfamily
C6M02_RS22030	COG0488	(ABC) transporter
C6M02_RS22035	COG2365	Tyrosine phosphatase family
C6M02_RS22040	COG1376	ErfK ybiS ycfS ynhG family protein
C6M02_RS22045	COG2188	Transcriptional regulator
C6M02_RS22050	COG2723	6-phospho-beta-galactosidase activity
C6M02_RS22055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6M02_RS22060	COG1321	iron dependent repressor
C6M02_RS22070	COG2194	sulfuric ester hydrolase activity
C6M02_RS22075	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C6M02_RS22090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6M02_RS22095	COG0765	amino acid transport
C6M02_RS22100	COG1126	abc transporter atp-binding protein
C6M02_RS22105	COG0668	transmembrane transport
C6M02_RS22115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6M02_RS22125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6M02_RS22135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6M02_RS22140	COG1199	ATP-dependent helicase activity
C6M02_RS22145	COG0513	Belongs to the DEAD box helicase family
C6M02_RS22150	COG3958	Transketolase
C6M02_RS22155	COG3959	Transketolase, thiamine diphosphate binding domain
C6M02_RS22160	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS22165	COG2271	Major facilitator Superfamily
C6M02_RS22170	COG0583	DNA-binding transcription factor activity
C6M02_RS22175	COG1309	transcriptional regulator
C6M02_RS22180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6M02_RS22185	COG1131	(ABC) transporter
C6M02_RS22190	COG0842	Transport permease protein
C6M02_RS22195	COG0842	Transport permease protein
C6M02_RS22210	COG3568	Endonuclease Exonuclease Phosphatase
C6M02_RS22215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6M02_RS22220	COG0392	lysyltransferase activity
C6M02_RS22235	COG0670	Belongs to the BI1 family
C6M02_RS22240	COG0314	molybdopterin synthase activity
C6M02_RS22245	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C6M02_RS22255	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6M02_RS22280	COG0745	RESPONSE REGULATOR receiver
C6M02_RS22285	COG0642	Histidine kinase
C6M02_RS22305	COG3344	reverse transcriptase
C6M02_RS22330	COG2226	methyltransferase
C6M02_RS22350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C6M02_RS22355	COG1881	PFAM PEBP family protein
C6M02_RS22395	COG4677	pectinesterase activity
C6M02_RS22435	COG0789	Transcriptional regulator
C6M02_RS22440	COG2200	EAL domain
C6M02_RS22465	COG0561	phosphatase activity
C6M02_RS22470	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C6M02_RS22475	COG4149	molybdate abc transporter
C6M02_RS22480	COG0725	ABC transporter, periplasmic molybdate-binding protein
C6M02_RS22490	COG3585	molybdate ion transport
C6M02_RS22490	COG2005	Transcriptional regulator
C6M02_RS22495	COG1119	ATPase activity
C6M02_RS22505	COG1085	galactose-1-phosphate uridylyltransferase
C6M02_RS22515	COG2017	converts alpha-aldose to the beta-anomer
C6M02_RS22525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C6M02_RS22540	COG3201	nicotinamide mononucleotide transporter
C6M02_RS22545	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C6M02_RS22575	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C6M02_RS22580	COG2885	chlorophyll binding
C6M02_RS22590	COG3064	Membrane
C6M02_RS22595	COG0848	biopolymer transport protein
C6M02_RS22600	COG0811	peptide transport
C6M02_RS22605	COG0824	Thioesterase
C6M02_RS22610	COG3790	cyd operon protein YbgE
C6M02_RS22615	COG4890	Cyd operon protein YbgT
C6M02_RS22620	COG1294	oxidase, subunit
C6M02_RS22625	COG1271	oxidase subunit
C6M02_RS22635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6M02_RS22645	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6M02_RS22650	COG0567	Dehydrogenase, E1 component
C6M02_RS22655	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6M02_RS22660	COG1053	succinate dehydrogenase
C6M02_RS22665	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C6M02_RS22670	COG2009	succinate dehydrogenase
C6M02_RS22715	COG1984	allophanate hydrolase subunit 2
C6M02_RS22720	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C6M02_RS22735	COG0415	Belongs to the DNA photolyase family
C6M02_RS22765	COG2205	protein histidine kinase activity
C6M02_RS22770	COG0745	RESPONSE REGULATOR receiver
C6M02_RS22780	COG0033	Phosphoglucomutase
C6M02_RS22790	COG0596	Alpha beta hydrolase
C6M02_RS22805	COG0735	belongs to the Fur family
C6M02_RS22850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6M02_RS22855	COG1846	Transcriptional regulator
C6M02_RS22855	COG1940	carbohydrate kinase activity
C6M02_RS22860	COG0647	UMP catabolic process
C6M02_RS22865	COG0367	asparagine synthase
C6M02_RS22910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6M02_RS22920	COG1702	phosphate starvation-inducible protein PhoH
C6M02_RS22930	COG4535	Mg2 and Co2 transporter CorC
C6M02_RS22945	COG0765	amino acid transport
C6M02_RS22950	COG0765	amino acid transport
C6M02_RS22955	COG1126	abc transporter atp-binding protein
C6M02_RS22970	COG2888	peptidyl-tyrosine sulfation
C6M02_RS22985	COG1466	dna polymerase III delta subunit
C6M02_RS23005	COG0799	negative regulation of ribosome biogenesis
C6M02_RS23015	COG0768	penicillin binding
C6M02_RS23020	COG0772	Belongs to the SEDS family
C6M02_RS23025	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6M02_RS23030	COG1686	Belongs to the peptidase S11 family
C6M02_RS23045	COG0583	DNA-binding transcription factor activity
C6M02_RS23060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6M02_RS23085	COG3069	C4-dicarboxylate transmembrane transporter activity
C6M02_RS23090	COG3719	Belongs to the RNase T2 family
C6M02_RS23095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6M02_RS23115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6M02_RS23120	COG0583	DNA-binding transcription factor activity
C6M02_RS23125	COG3969	phosphoadenosine phosphosulfate
C6M02_RS23130	COG1475	DNA binding
C6M02_RS23135	COG0436	Aminotransferase
C6M02_RS23160	COG1129	ABC transporter
C6M02_RS23165	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS23170	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS23180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6M02_RS23195	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C6M02_RS23205	COG0402	S-adenosylhomocysteine deaminase activity
C6M02_RS23215	COG0483	inositol monophosphate 1-phosphatase activity
C6M02_RS23220	COG2271	Major facilitator Superfamily
C6M02_RS23250	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS23255	COG1129	ABC transporter
C6M02_RS23260	COG0371	Dehydrogenase
C6M02_RS23265	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS23280	COG2879	small protein
C6M02_RS23285	COG1966	Carbon starvation protein
C6M02_RS23295	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS23300	COG1535	isochorismatase
C6M02_RS23300	COG3433	isochorismatase activity
C6M02_RS23305	COG1021	2,3-dihydroxybenzoate-AMP ligase
C6M02_RS23310	COG1169	isochorismate synthase
C6M02_RS23315	COG4592	Periplasmic binding protein
C6M02_RS23325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6M02_RS23330	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6M02_RS23335	COG1120	ATPase activity
C6M02_RS23340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6M02_RS23340	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C6M02_RS23345	COG3251	PFAM MbtH domain protein
C6M02_RS23350	COG2382	esterase
C6M02_RS23355	COG4771	TonB-dependent receptor
C6M02_RS23360	COG2977	Belongs to the P-Pant transferase superfamily
C6M02_RS23365	COG3958	Transketolase
C6M02_RS23370	COG3959	Transketolase, thiamine diphosphate binding domain
C6M02_RS23380	COG2390	Transcriptional regulator
C6M02_RS23385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C6M02_RS23390	COG1879	ABC-type sugar transport system periplasmic component
C6M02_RS23400	COG1129	ABC transporter
C6M02_RS23405	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS23415	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS23425	COG0583	DNA-binding transcription factor activity
C6M02_RS23430	COG0668	transmembrane transport
C6M02_RS23440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6M02_RS23470	COG0747	negative chemotaxis
C6M02_RS23475	COG0601	transmembrane transport
C6M02_RS23480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6M02_RS23485	COG0444	Belongs to the ABC transporter superfamily
C6M02_RS23490	COG4608	Belongs to the ABC transporter superfamily
C6M02_RS23500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C6M02_RS23505	COG4221	oxidoreductase activity
C6M02_RS23515	COG4215	(ABC) transporter
C6M02_RS23520	COG0765	amino acid transport
C6M02_RS23525	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C6M02_RS23540	COG0697	spore germination
C6M02_RS23550	COG3698	Phosphodiester glycosidase
C6M02_RS23600	COG2315	Protein conserved in bacteria
C6M02_RS23605	COG0778	Nitroreductase
C6M02_RS23615	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6M02_RS23625	COG3716	PTS system mannose fructose sorbose family IID component
C6M02_RS23630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6M02_RS23635	COG2222	sugar isomerase
C6M02_RS23640	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C6M02_RS23640	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C6M02_RS23660	COG0477	Major facilitator Superfamily
C6M02_RS23665	COG0668	transmembrane transport
C6M02_RS23695	COG3188	usher protein
C6M02_RS23710	COG2771	luxR family
C6M02_RS23720	COG0673	inositol 2-dehydrogenase activity
C6M02_RS23730	COG2211	Major facilitator Superfamily
C6M02_RS23735	COG1113	amino acid transport
C6M02_RS23750	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS23755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6M02_RS23765	COG0531	amino acid
C6M02_RS23815	COG0667	Aldo Keto reductase
C6M02_RS23820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6M02_RS23825	COG1473	amidohydrolase
C6M02_RS23845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6M02_RS23850	COG1120	ATPase activity
C6M02_RS23855	COG1566	PFAM secretion protein HlyD family protein
C6M02_RS23900	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS23905	COG1129	ABC transporter
C6M02_RS23920	COG0673	inositol 2-dehydrogenase activity
C6M02_RS23950	COG3104	oligopeptide transport
C6M02_RS23955	COG1982	Orn Lys Arg decarboxylase major
C6M02_RS23960	COG0531	amino acid
C6M02_RS23965	COG3710	Transcriptional regulator
C6M02_RS23975	COG1560	Kdo2-lipid A biosynthetic process
C6M02_RS23990	COG3188	usher protein
C6M02_RS23995	COG3121	Chaperone
C6M02_RS24000	COG3539	Fimbrial protein
C6M02_RS24060	COG2501	S4 domain
C6M02_RS24070	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6M02_RS24090	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C6M02_RS24095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6M02_RS24110	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C6M02_RS24115	COG4181	ATPase activity
C6M02_RS24120	COG2755	lipolytic protein G-D-S-L family
C6M02_RS24125	COG0300	oxidoreductase activity
C6M02_RS24130	COG3118	belongs to the thioredoxin family
C6M02_RS24140	COG0390	transport system, permease component
C6M02_RS24145	COG4619	ABC transporter
C6M02_RS24150	COG0330	HflC and HflK could
C6M02_RS24155	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6M02_RS24170	COG3735	TraB family
C6M02_RS24175	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6M02_RS24185	COG2223	nitrite transmembrane transporter activity
C6M02_RS24190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6M02_RS24190	COG4651	solute:proton antiporter activity
C6M02_RS24195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6M02_RS24240	COG2832	Protein of unknown function (DUF454)
C6M02_RS24245	COG3923	Primosomal replication protein n
C6M02_RS24255	COG5464	transposase or invertase
C6M02_RS24260	COG1196	nuclear chromosome segregation
C6M02_RS24260	COG3264	Mechanosensitive ion channel
C6M02_RS24280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6M02_RS24285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6M02_RS24300	COG0110	maltose O-acetyltransferase activity
C6M02_RS24345	COG1874	Beta-galactosidase
C6M02_RS24350	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C6M02_RS24355	COG3833	ABC-type maltose transport systems, permease component
C6M02_RS24360	COG1175	transmembrane transport
C6M02_RS24365	COG2182	Extracellular solute-binding protein
C6M02_RS24375	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6M02_RS24390	COG2364	Membrane
C6M02_RS24420	COG3695	enzyme binding
C6M02_RS24425	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C6M02_RS24430	COG1946	Acyl-CoA thioesterase
C6M02_RS24435	COG0004	ammonium transporteR
C6M02_RS24440	COG0347	Belongs to the P(II) protein family
C6M02_RS24445	COG1132	(ABC) transporter
C6M02_RS24450	COG1132	(ABC) transporter
C6M02_RS24455	COG1522	sequence-specific DNA binding
C6M02_RS24470	COG4533	DNA binding
C6M02_RS24480	COG0824	Thioesterase
C6M02_RS24485	COG1555	photosystem II stabilization
C6M02_RS24490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6M02_RS24495	COG0776	regulation of translation
C6M02_RS24500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C6M02_RS24530	COG0271	Belongs to the BolA IbaG family
C6M02_RS24535	COG3056	Lipoprotein
C6M02_RS24540	COG2223	nitrite transmembrane transporter activity
C6M02_RS24545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C6M02_RS24550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C6M02_RS24555	COG1845	cytochrome c oxidase, subunit III
C6M02_RS24560	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C6M02_RS24575	COG1414	Transcriptional regulator
C6M02_RS24580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C6M02_RS24585	COG1053	succinate dehydrogenase
C6M02_RS24595	COG1053	succinate dehydrogenase
C6M02_RS24610	COG0673	inositol 2-dehydrogenase activity
C6M02_RS24615	COG2814	Major facilitator Superfamily
C6M02_RS24625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C6M02_RS24630	COG0693	protein deglycase activity
C6M02_RS24650	COG0142	geranyltranstransferase activity
C6M02_RS24660	COG0667	Aldo Keto reductase
C6M02_RS24665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C6M02_RS24685	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6M02_RS24685	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6M02_RS24695	COG4238	major outer membrane lipoprotein
C6M02_RS24715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6M02_RS24720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6M02_RS24725	COG1862	Preprotein translocase
C6M02_RS24745	COG0450	alkyl hydroperoxide reductase
C6M02_RS24750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS24765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6M02_RS24775	COG1228	amidohydrolase
C6M02_RS24785	COG1335	isochorismatase
C6M02_RS24790	COG0583	DNA-binding transcription factor activity
C6M02_RS24795	COG0366	Alpha amylase catalytic
C6M02_RS24820	COG0420	3'-5' exonuclease activity
C6M02_RS24825	COG0419	ATPase involved in DNA repair
C6M02_RS24830	COG1940	carbohydrate kinase activity
C6M02_RS24845	COG4126	flavin adenine dinucleotide binding
C6M02_RS24855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C6M02_RS24860	COG3416	Protein conserved in bacteria
C6M02_RS24870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6M02_RS24880	COG1785	Belongs to the alkaline phosphatase family
C6M02_RS24920	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C6M02_RS24925	COG1335	isochorismatase
C6M02_RS24930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6M02_RS24935	COG0113	porphobilinogen synthase activity
C6M02_RS24945	COG2175	clavaminate synthase activity
C6M02_RS24950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6M02_RS24955	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C6M02_RS24960	COG4521	taurine ABC transporter
C6M02_RS24965	COG2040	homocysteine
C6M02_RS24970	COG0833	amino acid
C6M02_RS24980	COG4303	Ethanolamine ammonia lyase large subunit
C6M02_RS24985	COG4302	ethanolamine ammonia-lyase activity
C6M02_RS25020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6M02_RS25025	COG1126	abc transporter atp-binding protein
C6M02_RS25030	COG0765	amino acid transport
C6M02_RS25035	COG0765	amino acid transport
C6M02_RS25050	COG3188	usher protein
C6M02_RS25075	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C6M02_RS25085	COG3639	organic phosphonate transmembrane transporter activity
C6M02_RS25120	COG0791	NLP P60 protein
C6M02_RS25145	COG0582	viral genome integration into host DNA
C6M02_RS25150	COG1192	Involved in chromosome partitioning
C6M02_RS25210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C6M02_RS25215	COG0022	dehydrogenase e1 component
C6M02_RS25220	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6M02_RS25225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6M02_RS25250	COG1070	Carbohydrate kinase
C6M02_RS25255	COG1028	Short-chain dehydrogenase reductase Sdr
C6M02_RS25260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6M02_RS25265	COG3775	system Galactitol-specific IIC component
C6M02_RS25270	COG0625	glutathione transferase activity
C6M02_RS25275	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C6M02_RS25295	COG0579	oxidoreductase
C6M02_RS25300	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS25305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6M02_RS25310	COG1113	amino acid transport
C6M02_RS25315	COG1802	Transcriptional regulator
C6M02_RS25335	COG2195	Cleaves the N-terminal amino acid of tripeptides
C6M02_RS25340	COG0454	-acetyltransferase
C6M02_RS25355	COG2991	Protein conserved in bacteria
C6M02_RS25370	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C6M02_RS25375	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C6M02_RS25395	COG3034	peptidoglycan biosynthetic process
C6M02_RS25400	COG0121	glutamine amidotransferase
C6M02_RS25410	COG1960	acyl-CoA dehydrogenase activity
C6M02_RS25415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6M02_RS25425	COG0583	DNA-binding transcription factor activity
C6M02_RS25440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6M02_RS25450	COG2226	methyltransferase
C6M02_RS25460	COG0741	lytic transglycosylase activity
C6M02_RS25460	COG1388	LysM domain
C6M02_RS25465	COG2226	methyltransferase
C6M02_RS25475	COG2814	Major facilitator Superfamily
C6M02_RS25480	COG0583	DNA-binding transcription factor activity
C6M02_RS25485	COG0656	L-ascorbic acid biosynthetic process
C6M02_RS25525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C6M02_RS25535	COG2011	ABC-type metal ion transport system permease component
C6M02_RS25540	COG1464	Belongs to the NlpA lipoprotein family
C6M02_RS25550	COG1720	tRNA m6t6A37 methyltransferase activity
C6M02_RS25560	COG0791	NLP P60 protein
C6M02_RS25565	COG3015	lipoprotein NlpE involved in copper resistance
C6M02_RS25570	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6M02_RS25585	COG4568	rho-dependent transcription termination
C6M02_RS25595	COG0346	lactoylglutathione lyase activity
C6M02_RS25600	COG1982	Orn Lys Arg decarboxylase major
C6M02_RS25640	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C6M02_RS25650	COG0750	zinc metalloprotease
C6M02_RS25655	COG0575	Belongs to the CDS family
C6M02_RS25670	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C6M02_RS25695	COG0024	Methionine aminopeptidase
C6M02_RS25700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C6M02_RS25715	COG3835	regulator
C6M02_RS25720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6M02_RS25740	COG2860	membrane
C6M02_RS25760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6M02_RS25765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6M02_RS25770	COG1120	ATPase activity
C6M02_RS25780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6M02_RS25870	COG1643	Atp-dependent helicase
C6M02_RS25875	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C6M02_RS25895	COG0617	tRNA 3'-terminal CCA addition
C6M02_RS25900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C6M02_RS25920	COG0726	polysaccharide deacetylase
C6M02_RS25925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS25930	COG0842	Transport permease protein
C6M02_RS25935	COG1131	(ABC) transporter
C6M02_RS25940	COG0288	reversible hydration of carbon dioxide
C6M02_RS25950	COG4993	Dehydrogenase
C6M02_RS25955	COG2132	Multicopper oxidase
C6M02_RS26010	COG3064	Membrane
C6M02_RS26025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6M02_RS26030	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6M02_RS26035	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C6M02_RS26040	COG2186	Transcriptional regulator
C6M02_RS26045	COG1113	amino acid transport
C6M02_RS26050	COG2211	Major facilitator Superfamily
C6M02_RS26055	COG3940	Belongs to the glycosyl hydrolase 43 family
C6M02_RS26060	COG3725	Membrane protein required for beta-lactamase induction
C6M02_RS26065	COG3023	N-Acetylmuramoyl-L-alanine amidase
C6M02_RS26075	COG4969	Belongs to the N-Me-Phe pilin family
C6M02_RS26080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6M02_RS26085	COG1459	type II secretion system
C6M02_RS26110	COG0494	nUDIX hydrolase
C6M02_RS26130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C6M02_RS26135	COG0849	cell division
C6M02_RS26160	COG0772	Belongs to the SEDS family
C6M02_RS26175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6M02_RS26180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6M02_RS26185	COG0768	penicillin binding
C6M02_RS26210	COG1609	Transcriptional regulator
C6M02_RS26220	COG0028	Belongs to the TPP enzyme family
C6M02_RS26270	COG0738	Major facilitator superfamily
C6M02_RS26280	COG0583	DNA-binding transcription factor activity
C6M02_RS26285	COG2271	Major facilitator Superfamily
C6M02_RS26290	COG2814	Major facilitator Superfamily
C6M02_RS26310	COG1178	ABC-type Fe3 transport system permease component
C6M02_RS26320	COG0586	Pfam SNARE associated Golgi protein
C6M02_RS26340	COG0235	Class ii aldolase
C6M02_RS26345	COG0417	DNA replication proofreading
C6M02_RS26355	COG0564	pseudouridine synthase activity
C6M02_RS26370	COG3493	citrate carrier protein
C6M02_RS26385	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C6M02_RS26390	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C6M02_RS26400	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C6M02_RS26455	COG0505	Belongs to the CarA family
C6M02_RS26525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C6M02_RS26550	COG1047	Peptidyl-prolyl cis-trans
C6M02_RS26565	COG0196	riboflavin kinase activity
C6M02_RS26585	COG0583	DNA-binding transcription factor activity
C6M02_RS26610	COG4735	regulation of single-species biofilm formation
C6M02_RS26615	COG1584	GPR1 FUN34 yaaH family protein
C6M02_RS26620	COG0477	Major facilitator Superfamily
C6M02_RS26625	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6M02_RS26630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6M02_RS26635	COG1115	amino acid carrier protein
C6M02_RS26650	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C6M02_RS26660	COG0527	aspartate kinase activity
C6M02_RS26660	COG0460	homoserine dehydrogenase
C6M02_RS26670	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C6M02_RS26685	COG0745	RESPONSE REGULATOR receiver
C6M02_RS26690	COG4452	Inner membrane protein CreD
C6M02_RS26695	COG2205	protein histidine kinase activity
C6M02_RS26700	COG0745	RESPONSE REGULATOR receiver
C6M02_RS26705	COG3045	CreA protein
C6M02_RS26710	COG3708	Transcriptional regulator
C6M02_RS26710	COG2207	Transcriptional regulator
C6M02_RS26730	COG0741	lytic transglycosylase activity
C6M02_RS26740	COG0488	(ABC) transporter
C6M02_RS26750	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C6M02_RS26755	COG0560	Phosphoserine phosphatase
C6M02_RS26765	COG3726	membrane protein affecting hemolysin expression
C6M02_RS26795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6M02_RS26800	COG0084	hydrolase, TatD family'
C6M02_RS26805	COG4667	esterase of the alpha-beta hydrolase superfamily
C6M02_RS26815	COG2823	Periplasmic or secreted lipoprotein
C6M02_RS26825	COG1011	Hydrolase
C6M02_RS26830	COG0456	acetyltransferase
C6M02_RS26835	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C6M02_RS26865	COG3706	GGDEF domain
C6M02_RS26870	COG4114	ferric iron reductase
C6M02_RS26875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS26875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS26880	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6M02_RS26885	COG2197	response regulator
C6M02_RS26890	COG2197	response regulator
C6M02_RS26910	COG2966	Psort location CytoplasmicMembrane, score
C6M02_RS26925	COG1484	DNA-dependent DNA replication
C6M02_RS26940	COG5464	transposase or invertase
C6M02_RS26950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6M02_RS26955	COG3716	PTS system mannose fructose sorbose family IID component
C6M02_RS26960	COG3715	PTS system
C6M02_RS26975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C6M02_RS26975	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C6M02_RS26985	COG1063	alcohol dehydrogenase
C6M02_RS26990	COG1802	Transcriptional regulator
C6M02_RS26995	COG2271	Major facilitator Superfamily
C6M02_RS27000	COG1214	PFAM Peptidase M22, glycoprotease
C6M02_RS27000	COG0456	acetyltransferase
C6M02_RS27010	COG1737	Transcriptional regulator
C6M02_RS27015	COG0800	Aldolase
C6M02_RS27020	COG3734	2-keto-3-deoxy-galactonokinase
C6M02_RS27035	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
C6M02_RS27065	COG1846	Transcriptional regulator
C6M02_RS27070	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6M02_RS27080	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS27085	COG3384	dioxygenase
C6M02_RS27095	COG3971	2-oxopent-4-enoate hydratase activity
C6M02_RS27115	COG2368	4-hydroxyphenylacetate
C6M02_RS27120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6M02_RS27135	COG1966	Carbon starvation protein
C6M02_RS27140	COG2879	small protein
C6M02_RS27145	COG0523	cobalamin synthesis protein
C6M02_RS27155	COG1012	belongs to the aldehyde dehydrogenase family
C6M02_RS27160	COG5464	transposase or invertase
C6M02_RS27165	COG1917	Cupin 2, conserved barrel domain protein
C6M02_RS27165	COG2207	Transcriptional regulator
C6M02_RS27175	COG2733	membrane
C6M02_RS27190	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C6M02_RS27195	COG1924	4 iron, 4 sulfur cluster binding
C6M02_RS27210	COG1566	PFAM secretion protein HlyD family protein
C6M02_RS27220	COG5457	Domain of unknown function (DUF1127)
C6M02_RS27225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6M02_RS27235	COG0583	DNA-binding transcription factor activity
C6M02_RS27240	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6M02_RS27250	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS27255	COG1129	ABC transporter
C6M02_RS27260	COG1879	ABC-type sugar transport system periplasmic component
C6M02_RS27270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6M02_RS27275	COG1129	ABC transporter
C6M02_RS27275	COG0842	Transport permease protein
C6M02_RS27280	COG0842	Transport permease protein
C6M02_RS27315	COG2850	peptidyl-arginine hydroxylation
C6M02_RS27330	COG5002	protein histidine kinase activity
C6M02_RS27335	COG0745	RESPONSE REGULATOR receiver
C6M02_RS27345	COG1538	Outer membrane efflux protein
C6M02_RS27350	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6M02_RS27355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C6M02_RS27360	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6M02_RS27370	COG3040	lipid binding
C6M02_RS27375	COG0789	Transcriptional regulator
C6M02_RS27385	COG0300	oxidoreductase activity
C6M02_RS27400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C6M02_RS27420	COG3272	Protein of unknown function (DUF1722)
C6M02_RS27425	COG4580	involved in the transport of maltose and maltodextrins
C6M02_RS27435	COG2211	Major facilitator Superfamily
C6M02_RS27440	COG3507	Belongs to the glycosyl hydrolase 43 family
C6M02_RS27570	COG3039	Transposase
C6M02_RS27580	COG0582	viral genome integration into host DNA
C6M02_RS27595	COG0288	reversible hydration of carbon dioxide
C6M02_RS27600	COG0659	secondary active sulfate transmembrane transporter activity
C6M02_RS27605	COG1064	alcohol dehydrogenase
C6M02_RS27610	COG1175	transmembrane transport
C6M02_RS27615	COG0395	ABC-type sugar transport system, permease component
C6M02_RS27620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C6M02_RS27625	COG3842	ATPase activity
C6M02_RS27630	COG1653	transport
C6M02_RS27640	COG1082	Xylose isomerase domain protein TIM barrel
C6M02_RS27650	COG3962	Belongs to the TPP enzyme family
C6M02_RS27655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6M02_RS27660	COG0837	glucose binding
C6M02_RS27660	COG1737	Transcriptional regulator
C6M02_RS27695	COG3718	enzyme involved in inositol metabolism
C6M02_RS27710	COG0433	COG0433 Predicted ATPase
C6M02_RS27715	COG0795	lipopolysaccharide-transporting ATPase activity
C6M02_RS27720	COG0795	lipopolysaccharide-transporting ATPase activity
C6M02_RS27735	COG2927	DNA polymerase III (CHI subunit)
C6M02_RS27740	COG0525	valine-tRNA ligase activity
C6M02_RS27765	COG2188	Transcriptional regulator
C6M02_RS27770	COG1288	antiporter activity
C6M02_RS27775	COG1228	amidohydrolase
C6M02_RS27780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6M02_RS27785	COG2222	sugar isomerase
C6M02_RS27790	COG2731	YhcH YjgK YiaL family protein
C6M02_RS27835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6M02_RS27835	COG1263	PTS System
C6M02_RS27840	COG0366	Alpha amylase catalytic
C6M02_RS27845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6M02_RS27850	COG1486	melibiose metabolic process
C6M02_RS27870	COG0602	queuosine metabolic process
C6M02_RS27875	COG2026	Addiction module toxin, RelE StbE family
C6M02_RS27880	COG3077	Addiction module antitoxin, RelB DinJ family
C6M02_RS27885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6M02_RS27885	COG3711	transcriptional antiterminator
C6M02_RS27890	COG2706	6-phosphogluconolactonase activity
C6M02_RS27905	COG3964	amidohydrolase
C6M02_RS27940	COG0312	modulator of DNA gyrase
C6M02_RS27960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C6M02_RS27970	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS27975	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS27980	COG1129	ABC transporter
C6M02_RS27985	COG1879	ABC-type sugar transport system periplasmic component
C6M02_RS28005	COG2105	PFAM AIG2 family protein
C6M02_RS28010	COG2911	Protein conserved in bacteria
C6M02_RS28015	COG0729	surface antigen
C6M02_RS28025	COG1253	flavin adenine dinucleotide binding
C6M02_RS28040	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C6M02_RS28055	COG1733	regulation of RNA biosynthetic process
C6M02_RS28060	COG0702	epimerase
C6M02_RS28070	COG0697	spore germination
C6M02_RS28080	COG1113	amino acid transport
C6M02_RS28085	COG0545	Peptidyl-prolyl cis-trans isomerase
C6M02_RS28090	COG3061	Opacity-associated protein A
C6M02_RS28100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C6M02_RS28105	COG2965	DNA replication, synthesis of RNA primer
C6M02_RS28165	COG1073	alpha beta
C6M02_RS28170	COG3650	response to hydrogen peroxide
C6M02_RS28180	COG1960	acyl-CoA dehydrogenase activity
C6M02_RS28185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6M02_RS28190	COG0557	exoribonuclease II activity
C6M02_RS28205	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C6M02_RS28215	COG0330	HflC and HflK could
C6M02_RS28220	COG0330	HflC and HflK could
C6M02_RS28225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C6M02_RS28245	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6M02_RS28250	COG0802	atpase or kinase
C6M02_RS28255	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C6M02_RS28255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C6M02_RS28260	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C6M02_RS28285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6M02_RS28310	COG3264	Mechanosensitive ion channel
C6M02_RS28310	COG1511	domain protein
C6M02_RS28325	COG1053	succinate dehydrogenase
C6M02_RS28330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6M02_RS28350	COG2076	Multidrug Resistance protein
C6M02_RS28355	COG5510	response to toxic substance
C6M02_RS28370	COG1509	lysine 2,3-aminomutase activity
C6M02_RS28440	COG0531	amino acid
C6M02_RS28445	COG3030	protein affecting phage T7 exclusion by the F plasmid
C6M02_RS28455	COG1027	Aspartate ammonia-lyase
C6M02_RS28460	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C6M02_RS28475	COG1309	transcriptional regulator
C6M02_RS28505	COG0457	Tetratricopeptide repeat
C6M02_RS28510	COG0726	polysaccharide deacetylase
C6M02_RS28510	COG1649	PFAM Uncharacterised BCR, COG1649
C6M02_RS28515	COG1215	transferase activity, transferring glycosyl groups
C6M02_RS28535	COG0861	Integral membrane protein TerC family
C6M02_RS28570	COG1486	melibiose metabolic process
C6M02_RS28580	COG2169	Transcriptional regulator
C6M02_RS28595	COG2824	Alkylphosphonate utilization operon protein PhnA
C6M02_RS28600	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C6M02_RS28605	COG2188	Transcriptional regulator
C6M02_RS28610	COG3624	Phosphonate C-P lyase system protein PhnG
C6M02_RS28615	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
C6M02_RS28620	COG3626	phosphonate metabolism
C6M02_RS28625	COG3627	carbon phosphorus lyase activity
C6M02_RS28630	COG4107	phosphonate C-P lyase system protein PhnK
C6M02_RS28635	COG4778	phosphonate C-P lyase system protein PhnL
C6M02_RS28640	COG3454	Phosphonate metabolism
C6M02_RS28650	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C6M02_RS28660	COG4191	Histidine kinase
C6M02_RS28660	COG0784	Response regulator, receiver
C6M02_RS28665	COG1129	ABC transporter
C6M02_RS28670	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS28705	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C6M02_RS28710	COG1301	dicarboxylic acid transport
C6M02_RS28720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6M02_RS28730	COG3162	membrane
C6M02_RS28760	COG3539	Fimbrial protein
C6M02_RS28765	COG1346	cytolysis
C6M02_RS28770	COG1380	Effector of murein hydrolase LrgA
C6M02_RS28775	COG0583	DNA-binding transcription factor activity
C6M02_RS28780	COG0025	NhaP-type Na H and K H
C6M02_RS28785	COG2252	PERMEase
C6M02_RS28790	COG0625	glutathione transferase activity
C6M02_RS28795	COG0789	Transcriptional regulator
C6M02_RS28805	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C6M02_RS28840	COG1234	tRNA 3'-trailer cleavage
C6M02_RS28845	COG1609	Transcriptional regulator
C6M02_RS28850	COG0483	inositol monophosphate 1-phosphatase activity
C6M02_RS28865	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C6M02_RS28885	COG4771	TonB-dependent receptor
C6M02_RS28890	COG0741	lytic transglycosylase activity
C6M02_RS28910	COG2315	Protein conserved in bacteria
C6M02_RS28915	COG0432	Pfam Uncharacterised protein family UPF0047
C6M02_RS28930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6M02_RS28935	COG0305	Participates in initiation and elongation during chromosome replication
C6M02_RS28950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6M02_RS28960	COG0735	belongs to the Fur family
C6M02_RS28965	COG3237	CsbD-like
C6M02_RS28970	COG0534	Mate efflux family protein
C6M02_RS28980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C6M02_RS29060	COG0251	oxidation-reduction process
C6M02_RS29070	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C6M02_RS29090	COG0527	aspartate kinase activity
C6M02_RS29145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C6M02_RS29175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6M02_RS29185	COG0456	acetyltransferase
C6M02_RS29225	COG0151	Belongs to the GarS family
C6M02_RS29235	COG4191	Histidine kinase
C6M02_RS29240	COG3678	ATP-independent chaperone mediated protein folding
C6M02_RS29275	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C6M02_RS29290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6M02_RS29295	COG2104	thiamine diphosphate biosynthetic process
C6M02_RS29315	COG3706	GGDEF domain
C6M02_RS29325	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6M02_RS29330	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C6M02_RS29370	COG0250	Participates in transcription elongation, termination and antitermination
C6M02_RS29420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C6M02_RS29455	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C6M02_RS29465	COG1739	Uncharacterized protein family UPF0029
C6M02_RS29510	COG0805	protein transport
C6M02_RS29530	COG3165	ubiquinone biosynthetic process from chorismate
C6M02_RS29560	COG0583	DNA-binding transcription factor activity
C6M02_RS29565	COG0697	spore germination
C6M02_RS29570	COG0561	phosphatase activity
C6M02_RS29575	COG2267	carboxylic ester hydrolase activity
C6M02_RS29580	COG1280	lysine exporter protein (LysE YggA)
C6M02_RS29590	COG1280	lysine exporter protein (LysE YggA)
C6M02_RS29625	COG0210	DNA helicase
C6M02_RS29630	COG1011	Hydrolase
C6M02_RS29660	COG3072	Adenylate cyclase
C6M02_RS29675	COG2959	enzyme of heme biosynthesis
C6M02_RS29680	COG3071	HemY protein
C6M02_RS29725	COG2244	polysaccharide biosynthetic process
C6M02_RS29730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C6M02_RS29735	COG0456	acetyltransferase
C6M02_RS29740	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C6M02_RS29745	COG1088	dTDP-glucose 4,6-dehydratase activity
C6M02_RS29750	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C6M02_RS29755	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6M02_RS29765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C6M02_RS29770	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C6M02_RS29780	COG3118	belongs to the thioredoxin family
C6M02_RS29810	COG1811	Na channel or pump
C6M02_RS29820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6M02_RS29825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6M02_RS29835	COG0583	DNA-binding transcription factor activity
C6M02_RS29840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6M02_RS29855	COG3978	acetolactate synthase activity
C6M02_RS29875	COG3085	chromosome segregation
C6M02_RS29950	COG0583	DNA-binding transcription factor activity
C6M02_RS29975	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C6M02_RS29990	COG3443	Belongs to the bacterial solute-binding protein 9 family
C6M02_RS29995	COG2207	Transcriptional regulator
C6M02_RS30005	COG0371	Dehydrogenase
C6M02_RS30010	COG0697	spore germination
C6M02_RS30020	COG0583	DNA-binding transcription factor activity
C6M02_RS30030	COG0737	Belongs to the 5'-nucleotidase family
C6M02_RS30040	COG0527	aspartate kinase activity
C6M02_RS30040	COG0460	homoserine dehydrogenase
C6M02_RS30045	COG0626	cystathionine gamma-synthase activity
C6M02_RS30060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C6M02_RS30065	COG1609	Transcriptional regulator
C6M02_RS30070	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C6M02_RS30085	COG1575	Belongs to the MenA family. Type 1 subfamily
C6M02_RS30105	COG3678	ATP-independent chaperone mediated protein folding
C6M02_RS30110	COG0745	RESPONSE REGULATOR receiver
C6M02_RS30115	COG2205	protein histidine kinase activity
C6M02_RS30120	COG2258	MOSC domain
C6M02_RS30125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6M02_RS30170	COG1129	ABC transporter
C6M02_RS30175	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS30180	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS30185	COG1454	alcohol dehydrogenase
C6M02_RS30195	COG2211	Major facilitator Superfamily
C6M02_RS30255	COG0205	6-phosphofructokinase activity
C6M02_RS30275	COG0243	molybdopterin cofactor binding
C6M02_RS30275	COG3383	formate dehydrogenase (NAD+) activity
C6M02_RS30280	COG0243	molybdopterin cofactor binding
C6M02_RS30280	COG3383	formate dehydrogenase (NAD+) activity
C6M02_RS30285	COG0437	4 iron, 4 sulfur cluster binding
C6M02_RS30290	COG2864	formate dehydrogenase
C6M02_RS30305	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C6M02_RS30310	COG0657	acetylesterase activity
C6M02_RS30315	COG0456	acetyltransferase
C6M02_RS30330	COG1011	Hydrolase
C6M02_RS30350	COG3852	Histidine kinase
C6M02_RS30360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6M02_RS30390	COG0204	Acyl-transferase
C6M02_RS30400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6M02_RS30405	COG3084	Protein conserved in bacteria
C6M02_RS30415	COG1763	Mo-molybdopterin cofactor biosynthetic process
C6M02_RS30445	COG2186	Transcriptional regulator
C6M02_RS30450	COG0477	Major facilitator Superfamily
C6M02_RS30455	COG1609	Transcriptional regulator
C6M02_RS30460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6M02_RS30470	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6M02_RS30475	COG1129	ABC transporter
C6M02_RS30505	COG1522	sequence-specific DNA binding
C6M02_RS30510	COG0716	FMN binding
C6M02_RS30525	COG3312	ion transport
C6M02_RS30575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6M02_RS30580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6M02_RS30585	COG0573	inorganic phosphate transmembrane transporter activity
C6M02_RS30590	COG0581	inorganic phosphate transmembrane transporter activity
C6M02_RS30595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6M02_RS30600	COG0704	Plays a role in the regulation of phosphate uptake
C6M02_RS30615	COG2382	esterase
C6M02_RS30620	COG0363	glucosamine-6-phosphate deaminase activity
C6M02_RS30625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6M02_RS30635	COG2252	PERMEase
C6M02_RS30640	COG0431	NADPH-dependent FMN reductase
C6M02_RS30645	COG2091	lysine biosynthetic process via aminoadipic acid
C6M02_RS30680	COG0759	Could be involved in insertion of integral membrane proteins into the membrane