locus-tag	class	description
H3G96_RS00020	COG0187	DNA topoisomerase II activity
H3G96_RS00025	COG0561	phosphatase activity
H3G96_RS00040	COG2186	Transcriptional regulator
H3G96_RS00060	COG2271	Major facilitator Superfamily
H3G96_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
H3G96_RS00070	COG5645	(Lipo)protein
H3G96_RS00085	COG3645	SOS response
H3G96_RS00095	COG2188	Transcriptional regulator
H3G96_RS00110	COG2149	membrane
H3G96_RS00130	COG2610	gluconate transmembrane transporter activity
H3G96_RS00140	COG0583	DNA-binding transcription factor activity
H3G96_RS00145	COG2814	Major facilitator Superfamily
H3G96_RS00175	COG0028	Belongs to the TPP enzyme family
H3G96_RS00180	COG0440	acetolactate synthase activity
H3G96_RS00185	COG2197	response regulator
H3G96_RS00195	COG2271	Major facilitator Superfamily
H3G96_RS00235	COG2188	Transcriptional regulator
H3G96_RS00260	COG4580	involved in the transport of maltose and maltodextrins
H3G96_RS00265	COG1447	Phosphotransferase system cellobiose-specific component IIA
H3G96_RS00270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS00270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS00280	COG1609	Transcriptional regulator
H3G96_RS00290	COG3384	dioxygenase
H3G96_RS00295	COG0583	DNA-binding transcription factor activity
H3G96_RS00300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H3G96_RS00305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H3G96_RS00310	COG2828	Protein conserved in bacteria
H3G96_RS00325	COG0697	spore germination
H3G96_RS00330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H3G96_RS00330	COG1263	PTS System
H3G96_RS00340	COG2814	Major facilitator Superfamily
H3G96_RS00395	COG0583	DNA-binding transcription factor activity
H3G96_RS00420	COG1464	Belongs to the NlpA lipoprotein family
H3G96_RS00435	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H3G96_RS00445	COG1064	alcohol dehydrogenase
H3G96_RS00475	COG2211	Major facilitator Superfamily
H3G96_RS00480	COG1501	Belongs to the glycosyl hydrolase 31 family
H3G96_RS00490	COG1486	melibiose metabolic process
H3G96_RS00495	COG1263	PTS System
H3G96_RS00495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H3G96_RS00500	COG2982	Protein involved in outer membrane biogenesis
H3G96_RS00505	COG2233	PERMEase
H3G96_RS00510	COG0786	glutamate:sodium symporter activity
H3G96_RS00530	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H3G96_RS00555	COG3152	Membrane
H3G96_RS00565	COG1494	fructose-1,6-bisphosphatase
H3G96_RS00570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H3G96_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H3G96_RS00580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H3G96_RS00600	COG2860	membrane
H3G96_RS00610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H3G96_RS00610	COG2169	Transcriptional regulator
H3G96_RS00615	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H3G96_RS00620	COG1561	YicC-like family, N-terminal region
H3G96_RS00625	COG3039	Transposase
H3G96_RS00645	COG1131	(ABC) transporter
H3G96_RS00650	COG0842	Transport permease protein
H3G96_RS00675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H3G96_RS00710	COG1519	Transferase
H3G96_RS00715	COG1216	Glycosyl transferase, family 2
H3G96_RS00720	COG0438	transferase activity, transferring glycosyl groups
H3G96_RS00730	COG0859	PFAM glycosyl transferase family 9
H3G96_RS00755	COG0859	PFAM glycosyl transferase family 9
H3G96_RS00770	COG0156	8-amino-7-oxononanoate synthase activity
H3G96_RS00780	COG0463	Glycosyl transferase, family 2
H3G96_RS00785	COG2861	carbohydrate metabolic process
H3G96_RS00790	COG4942	peptidase
H3G96_RS00800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H3G96_RS00805	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H3G96_RS00825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H3G96_RS00835	COG2186	Transcriptional regulator
H3G96_RS00855	COG3722	fumarate hydratase activity
H3G96_RS00875	COG1566	PFAM secretion protein HlyD family protein
H3G96_RS00880	COG0625	glutathione transferase activity
H3G96_RS00890	COG3276	selenocysteine insertion sequence binding
H3G96_RS00895	COG1414	Transcriptional regulator
H3G96_RS00900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H3G96_RS00905	COG3977	Valine--pyruvate aminotransferase
H3G96_RS00910	COG0366	Alpha amylase catalytic
H3G96_RS00915	COG2992	FlgJ-related protein
H3G96_RS00920	COG1609	Transcriptional regulator
H3G96_RS00920	COG2207	Transcriptional regulator
H3G96_RS00925	COG4214	carbohydrate transport
H3G96_RS00935	COG4213	ABC transporter substrate-binding protein
H3G96_RS00950	COG4682	membrane
H3G96_RS00955	COG4682	membrane
H3G96_RS00960	COG3274	enterobacterial common antigen metabolic process
H3G96_RS00995	COG1278	Cold shock
H3G96_RS01000	COG2944	sequence-specific DNA binding
H3G96_RS01005	COG2814	Major facilitator Superfamily
H3G96_RS01025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H3G96_RS01035	COG1609	Transcriptional regulator
H3G96_RS01040	COG2885	chlorophyll binding
H3G96_RS01045	COG0243	molybdopterin cofactor binding
H3G96_RS01050	COG0456	acetyltransferase
H3G96_RS01055	COG2818	Glycosylase
H3G96_RS01060	COG5571	outer membrane autotransporter
H3G96_RS01065	COG2223	nitrite transmembrane transporter activity
H3G96_RS01095	COG0747	negative chemotaxis
H3G96_RS01100	COG0601	transmembrane transport
H3G96_RS01105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H3G96_RS01110	COG0444	Belongs to the ABC transporter superfamily
H3G96_RS01115	COG4608	Belongs to the ABC transporter superfamily
H3G96_RS01140	COG1215	transferase activity, transferring glycosyl groups
H3G96_RS01145	COG0457	Tetratricopeptide repeat
H3G96_RS01160	COG2194	sulfuric ester hydrolase activity
H3G96_RS01190	COG1215	transferase activity, transferring glycosyl groups
H3G96_RS01195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H3G96_RS01200	COG0457	Tetratricopeptide repeat
H3G96_RS01200	COG3118	belongs to the thioredoxin family
H3G96_RS01205	COG2200	EAL domain
H3G96_RS01205	COG2199	diguanylate cyclase activity
H3G96_RS01215	COG0612	Peptidase, M16
H3G96_RS01225	COG2982	Protein involved in outer membrane biogenesis
H3G96_RS01230	COG0477	Major facilitator Superfamily
H3G96_RS01235	COG1295	ribonuclease BN
H3G96_RS01240	COG0583	DNA-binding transcription factor activity
H3G96_RS01245	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS01250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H3G96_RS01260	COG1454	alcohol dehydrogenase
H3G96_RS01270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H3G96_RS01275	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H3G96_RS01280	COG0671	phosphoesterase, PA-phosphatase related
H3G96_RS01300	COG0589	response to stress
H3G96_RS01310	COG0306	phosphate transporter
H3G96_RS01315	COG2081	HI0933 family
H3G96_RS01320	COG2239	Acts as a magnesium transporter
H3G96_RS01330	COG1124	(ABC) transporter
H3G96_RS01340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H3G96_RS01345	COG0601	transmembrane transport
H3G96_RS01350	COG0747	negative chemotaxis
H3G96_RS01360	COG3479	Phenolic acid decarboxylase
H3G96_RS01400	COG0628	permease
H3G96_RS01405	COG0477	Major facilitator Superfamily
H3G96_RS01415	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H3G96_RS01430	COG3714	YhhN family
H3G96_RS01440	COG3776	membrane
H3G96_RS01445	COG0742	ribosomal rna small subunit methyltransferase
H3G96_RS01450	COG0552	protein localization to endoplasmic reticulum
H3G96_RS01455	COG2884	Cell division ATP-binding protein ftsE
H3G96_RS01460	COG2177	Part of the ABC transporter FtsEX involved in
H3G96_RS01475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H3G96_RS01485	COG0683	leucine binding
H3G96_RS01495	COG0683	leucine binding
H3G96_RS01500	COG0559	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS01550	COG0584	glycerophosphoryl diester phosphodiesterase
H3G96_RS01560	COG0405	Gamma-glutamyltransferase
H3G96_RS01565	COG1247	-acetyltransferase
H3G96_RS01575	COG0673	inositol 2-dehydrogenase activity
H3G96_RS01580	COG1741	Belongs to the pirin family
H3G96_RS01585	COG1609	Transcriptional regulator
H3G96_RS01590	COG3265	gluconokinase activity
H3G96_RS01595	COG2610	gluconate transmembrane transporter activity
H3G96_RS01605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H3G96_RS01630	COG0058	SHG alpha-glucan phosphorylase activity
H3G96_RS01645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H3G96_RS01660	COG1349	DNA-binding transcription factor activity
H3G96_RS01670	COG0058	SHG alpha-glucan phosphorylase activity
H3G96_RS01675	COG1640	4-alpha-glucanotransferase
H3G96_RS01680	COG2610	gluconate transmembrane transporter activity
H3G96_RS01690	COG1040	competence protein
H3G96_RS01715	COG1918	ferrous iron import across plasma membrane
H3G96_RS01720	COG2183	response to ionizing radiation
H3G96_RS01725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H3G96_RS01750	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H3G96_RS01755	COG1011	Hydrolase
H3G96_RS01765	COG0494	nUDIX hydrolase
H3G96_RS01770	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H3G96_RS01795	COG4796	Type ii and iii secretion system protein
H3G96_RS01810	COG3266	domain, Protein
H3G96_RS01815	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H3G96_RS01820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H3G96_RS01845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H3G96_RS01850	COG0402	S-adenosylhomocysteine deaminase activity
H3G96_RS01855	COG0738	Major facilitator superfamily
H3G96_RS01880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H3G96_RS01885	COG1289	transmembrane transporter activity
H3G96_RS01895	COG1765	OsmC-like protein
H3G96_RS01900	COG3954	Phosphoribulokinase
H3G96_RS01910	COG0429	hydrolase of the alpha beta-hydrolase fold
H3G96_RS01915	COG0488	(ABC) transporter
H3G96_RS01930	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H3G96_RS01935	COG1047	Peptidyl-prolyl cis-trans
H3G96_RS01945	COG0545	Peptidyl-prolyl cis-trans isomerase
H3G96_RS01950	COG2964	Protein conserved in bacteria
H3G96_RS02005	COG0051	transcription antitermination factor activity, RNA binding
H3G96_RS02030	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H3G96_RS02045	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H3G96_RS02110	COG0201	protein transport
H3G96_RS02135	COG0202	RNA polymerase activity
H3G96_RS02150	COG0789	Transcriptional regulator
H3G96_RS02155	COG3036	rescue of stalled ribosome
H3G96_RS02185	COG0758	DNA mediated transformation
H3G96_RS02195	COG0551	DNA topoisomerase type I activity
H3G96_RS02215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H3G96_RS02235	COG0456	acetyltransferase
H3G96_RS02245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H3G96_RS02275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H3G96_RS02330	COG0527	aspartate kinase activity
H3G96_RS02340	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H3G96_RS02350	COG0251	oxidation-reduction process
H3G96_RS02420	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H3G96_RS02430	COG0534	Mate efflux family protein
H3G96_RS02440	COG3237	CsbD-like
H3G96_RS02445	COG0735	belongs to the Fur family
H3G96_RS02455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H3G96_RS02470	COG0305	Participates in initiation and elongation during chromosome replication
H3G96_RS02475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H3G96_RS02490	COG0432	Pfam Uncharacterised protein family UPF0047
H3G96_RS02495	COG2315	Protein conserved in bacteria
H3G96_RS02510	COG0741	lytic transglycosylase activity
H3G96_RS02515	COG4771	TonB-dependent receptor
H3G96_RS02535	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H3G96_RS02545	COG0483	inositol monophosphate 1-phosphatase activity
H3G96_RS02550	COG1609	Transcriptional regulator
H3G96_RS02555	COG1234	tRNA 3'-trailer cleavage
H3G96_RS02585	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H3G96_RS02595	COG0789	Transcriptional regulator
H3G96_RS02600	COG0625	glutathione transferase activity
H3G96_RS02605	COG2252	PERMEase
H3G96_RS02610	COG0025	NhaP-type Na H and K H
H3G96_RS02615	COG0583	DNA-binding transcription factor activity
H3G96_RS02620	COG1380	Effector of murein hydrolase LrgA
H3G96_RS02625	COG1346	cytolysis
H3G96_RS02630	COG3539	Fimbrial protein
H3G96_RS02660	COG3162	membrane
H3G96_RS02665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H3G96_RS02675	COG1301	dicarboxylic acid transport
H3G96_RS02680	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H3G96_RS02715	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS02720	COG1129	ABC transporter
H3G96_RS02725	COG4191	Histidine kinase
H3G96_RS02725	COG0784	Response regulator, receiver
H3G96_RS02735	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H3G96_RS02745	COG3454	Phosphonate metabolism
H3G96_RS02750	COG4778	phosphonate C-P lyase system protein PhnL
H3G96_RS02755	COG4107	phosphonate C-P lyase system protein PhnK
H3G96_RS02760	COG3627	carbon phosphorus lyase activity
H3G96_RS02765	COG3626	phosphonate metabolism
H3G96_RS02770	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
H3G96_RS02775	COG3624	Phosphonate C-P lyase system protein PhnG
H3G96_RS02780	COG2188	Transcriptional regulator
H3G96_RS02785	COG2764	glyoxalase bleomycin resistance protein dioxygenase
H3G96_RS02790	COG2824	Alkylphosphonate utilization operon protein PhnA
H3G96_RS02800	COG2169	Transcriptional regulator
H3G96_RS02805	COG1486	melibiose metabolic process
H3G96_RS02850	COG0861	Integral membrane protein TerC family
H3G96_RS02865	COG1215	transferase activity, transferring glycosyl groups
H3G96_RS02870	COG0726	polysaccharide deacetylase
H3G96_RS02870	COG1649	PFAM Uncharacterised BCR, COG1649
H3G96_RS02875	COG0457	Tetratricopeptide repeat
H3G96_RS02905	COG1309	transcriptional regulator
H3G96_RS02920	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H3G96_RS02925	COG1027	Aspartate ammonia-lyase
H3G96_RS02930	COG3030	protein affecting phage T7 exclusion by the F plasmid
H3G96_RS02935	COG0531	amino acid
H3G96_RS03005	COG1509	lysine 2,3-aminomutase activity
H3G96_RS03020	COG5510	response to toxic substance
H3G96_RS03025	COG2076	Multidrug Resistance protein
H3G96_RS03045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H3G96_RS03050	COG1053	succinate dehydrogenase
H3G96_RS03065	COG3264	Mechanosensitive ion channel
H3G96_RS03065	COG1511	domain protein
H3G96_RS03085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3G96_RS03105	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H3G96_RS03110	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H3G96_RS03110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H3G96_RS03115	COG0802	atpase or kinase
H3G96_RS03120	COG0860	N-Acetylmuramoyl-L-alanine amidase
H3G96_RS03140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H3G96_RS03145	COG0330	HflC and HflK could
H3G96_RS03150	COG0330	HflC and HflK could
H3G96_RS03160	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H3G96_RS03175	COG0557	exoribonuclease II activity
H3G96_RS03180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H3G96_RS03185	COG1960	acyl-CoA dehydrogenase activity
H3G96_RS03195	COG3650	response to hydrogen peroxide
H3G96_RS03200	COG1073	alpha beta
H3G96_RS03260	COG2965	DNA replication, synthesis of RNA primer
H3G96_RS03265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H3G96_RS03275	COG3061	Opacity-associated protein A
H3G96_RS03280	COG0545	Peptidyl-prolyl cis-trans isomerase
H3G96_RS03285	COG1113	amino acid transport
H3G96_RS03295	COG0697	spore germination
H3G96_RS03305	COG0702	epimerase
H3G96_RS03310	COG1733	regulation of RNA biosynthetic process
H3G96_RS03325	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H3G96_RS03340	COG1253	flavin adenine dinucleotide binding
H3G96_RS03350	COG0729	surface antigen
H3G96_RS03355	COG2911	Protein conserved in bacteria
H3G96_RS03360	COG2105	PFAM AIG2 family protein
H3G96_RS03380	COG1879	ABC-type sugar transport system periplasmic component
H3G96_RS03385	COG1129	ABC transporter
H3G96_RS03390	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS03395	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS03405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H3G96_RS03430	COG0312	modulator of DNA gyrase
H3G96_RS03470	COG3964	amidohydrolase
H3G96_RS03485	COG2706	6-phosphogluconolactonase activity
H3G96_RS03490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS03490	COG3711	transcriptional antiterminator
H3G96_RS03495	COG3077	Addiction module antitoxin, RelB DinJ family
H3G96_RS03500	COG2026	Addiction module toxin, RelE StbE family
H3G96_RS03505	COG0602	queuosine metabolic process
H3G96_RS03530	COG1486	melibiose metabolic process
H3G96_RS03535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS03540	COG0366	Alpha amylase catalytic
H3G96_RS03545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H3G96_RS03545	COG1263	PTS System
H3G96_RS03580	COG2731	YhcH YjgK YiaL family protein
H3G96_RS03585	COG2222	sugar isomerase
H3G96_RS03590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H3G96_RS03595	COG1228	amidohydrolase
H3G96_RS03600	COG1288	antiporter activity
H3G96_RS03605	COG2188	Transcriptional regulator
H3G96_RS03630	COG0525	valine-tRNA ligase activity
H3G96_RS03635	COG2927	DNA polymerase III (CHI subunit)
H3G96_RS03645	COG0795	lipopolysaccharide-transporting ATPase activity
H3G96_RS03650	COG0795	lipopolysaccharide-transporting ATPase activity
H3G96_RS03655	COG0433	COG0433 Predicted ATPase
H3G96_RS03670	COG3718	enzyme involved in inositol metabolism
H3G96_RS03675	COG1737	Transcriptional regulator
H3G96_RS03675	COG0837	glucose binding
H3G96_RS03680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H3G96_RS03685	COG3962	Belongs to the TPP enzyme family
H3G96_RS03695	COG1082	Xylose isomerase domain protein TIM barrel
H3G96_RS03705	COG1653	transport
H3G96_RS03710	COG3842	ATPase activity
H3G96_RS03715	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H3G96_RS03720	COG0395	ABC-type sugar transport system, permease component
H3G96_RS03725	COG1175	transmembrane transport
H3G96_RS03730	COG1064	alcohol dehydrogenase
H3G96_RS03735	COG0659	secondary active sulfate transmembrane transporter activity
H3G96_RS03740	COG0288	reversible hydration of carbon dioxide
H3G96_RS03750	COG0582	viral genome integration into host DNA
H3G96_RS03855	COG3507	Belongs to the glycosyl hydrolase 43 family
H3G96_RS03860	COG2211	Major facilitator Superfamily
H3G96_RS03870	COG4580	involved in the transport of maltose and maltodextrins
H3G96_RS03875	COG3272	Protein of unknown function (DUF1722)
H3G96_RS03895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H3G96_RS03910	COG0300	oxidoreductase activity
H3G96_RS03920	COG0789	Transcriptional regulator
H3G96_RS03925	COG3040	lipid binding
H3G96_RS03935	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H3G96_RS03940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H3G96_RS03945	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H3G96_RS03950	COG1538	Outer membrane efflux protein
H3G96_RS03955	COG0745	RESPONSE REGULATOR receiver
H3G96_RS03960	COG5002	protein histidine kinase activity
H3G96_RS03975	COG2850	peptidyl-arginine hydroxylation
H3G96_RS04005	COG0842	Transport permease protein
H3G96_RS04010	COG1129	ABC transporter
H3G96_RS04010	COG0842	Transport permease protein
H3G96_RS04015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H3G96_RS04025	COG1879	ABC-type sugar transport system periplasmic component
H3G96_RS04030	COG1129	ABC transporter
H3G96_RS04035	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS04045	COG2249	NAD(P)H dehydrogenase (quinone) activity
H3G96_RS04050	COG0583	DNA-binding transcription factor activity
H3G96_RS04060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H3G96_RS04065	COG5457	Domain of unknown function (DUF1127)
H3G96_RS04075	COG1566	PFAM secretion protein HlyD family protein
H3G96_RS04090	COG1924	4 iron, 4 sulfur cluster binding
H3G96_RS04095	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
H3G96_RS04110	COG2733	membrane
H3G96_RS04120	COG2207	Transcriptional regulator
H3G96_RS04120	COG1917	Cupin 2, conserved barrel domain protein
H3G96_RS04125	COG5464	transposase or invertase
H3G96_RS04130	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS04140	COG0523	cobalamin synthesis protein
H3G96_RS04145	COG2879	small protein
H3G96_RS04150	COG1966	Carbon starvation protein
H3G96_RS04165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H3G96_RS04170	COG2368	4-hydroxyphenylacetate
H3G96_RS04190	COG3971	2-oxopent-4-enoate hydratase activity
H3G96_RS04200	COG3384	dioxygenase
H3G96_RS04205	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS04215	COG0179	Fumarylacetoacetate (FAA) hydrolase
H3G96_RS04225	COG1846	Transcriptional regulator
H3G96_RS04255	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
H3G96_RS04270	COG3734	2-keto-3-deoxy-galactonokinase
H3G96_RS04275	COG0800	Aldolase
H3G96_RS04280	COG1737	Transcriptional regulator
H3G96_RS04290	COG1214	PFAM Peptidase M22, glycoprotease
H3G96_RS04290	COG0456	acetyltransferase
H3G96_RS04295	COG2271	Major facilitator Superfamily
H3G96_RS04300	COG1802	Transcriptional regulator
H3G96_RS04305	COG1063	alcohol dehydrogenase
H3G96_RS04315	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H3G96_RS04315	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H3G96_RS04330	COG3715	PTS system
H3G96_RS04335	COG3716	PTS system mannose fructose sorbose family IID component
H3G96_RS04340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H3G96_RS04350	COG5464	transposase or invertase
H3G96_RS04365	COG1484	DNA-dependent DNA replication
H3G96_RS04380	COG2966	Psort location CytoplasmicMembrane, score
H3G96_RS04395	COG2197	response regulator
H3G96_RS04400	COG2197	response regulator
H3G96_RS04405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H3G96_RS04410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS04410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS04415	COG4114	ferric iron reductase
H3G96_RS04420	COG3706	GGDEF domain
H3G96_RS04455	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
H3G96_RS04460	COG0456	acetyltransferase
H3G96_RS04465	COG1011	Hydrolase
H3G96_RS04475	COG2823	Periplasmic or secreted lipoprotein
H3G96_RS04485	COG4667	esterase of the alpha-beta hydrolase superfamily
H3G96_RS04490	COG0084	hydrolase, TatD family'
H3G96_RS04495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H3G96_RS04525	COG3726	membrane protein affecting hemolysin expression
H3G96_RS04530	COG0560	Phosphoserine phosphatase
H3G96_RS04535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H3G96_RS04545	COG0488	(ABC) transporter
H3G96_RS04550	COG0741	lytic transglycosylase activity
H3G96_RS04570	COG3708	Transcriptional regulator
H3G96_RS04570	COG2207	Transcriptional regulator
H3G96_RS04575	COG3045	CreA protein
H3G96_RS04580	COG0745	RESPONSE REGULATOR receiver
H3G96_RS04585	COG2205	protein histidine kinase activity
H3G96_RS04590	COG4452	Inner membrane protein CreD
H3G96_RS04595	COG0745	RESPONSE REGULATOR receiver
H3G96_RS04605	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
H3G96_RS04615	COG0527	aspartate kinase activity
H3G96_RS04615	COG0460	homoserine dehydrogenase
H3G96_RS04625	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H3G96_RS04640	COG1115	amino acid carrier protein
H3G96_RS04645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H3G96_RS04650	COG0521	Mo-molybdopterin cofactor biosynthetic process
H3G96_RS04655	COG0477	Major facilitator Superfamily
H3G96_RS04660	COG1584	GPR1 FUN34 yaaH family protein
H3G96_RS04665	COG4735	regulation of single-species biofilm formation
H3G96_RS04690	COG0583	DNA-binding transcription factor activity
H3G96_RS04700	COG0196	riboflavin kinase activity
H3G96_RS04715	COG1047	Peptidyl-prolyl cis-trans
H3G96_RS04740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H3G96_RS04805	COG0505	Belongs to the CarA family
H3G96_RS04850	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H3G96_RS04860	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H3G96_RS04865	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H3G96_RS04880	COG3493	citrate carrier protein
H3G96_RS04890	COG0564	pseudouridine synthase activity
H3G96_RS04900	COG0417	DNA replication proofreading
H3G96_RS04905	COG0235	Class ii aldolase
H3G96_RS04925	COG0586	Pfam SNARE associated Golgi protein
H3G96_RS04935	COG1178	ABC-type Fe3 transport system permease component
H3G96_RS04955	COG2814	Major facilitator Superfamily
H3G96_RS04960	COG2271	Major facilitator Superfamily
H3G96_RS04965	COG0583	DNA-binding transcription factor activity
H3G96_RS04975	COG0738	Major facilitator superfamily
H3G96_RS05020	COG0028	Belongs to the TPP enzyme family
H3G96_RS05030	COG1609	Transcriptional regulator
H3G96_RS05050	COG0768	penicillin binding
H3G96_RS05055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H3G96_RS05060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H3G96_RS05075	COG0772	Belongs to the SEDS family
H3G96_RS05100	COG0849	cell division
H3G96_RS05105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H3G96_RS05125	COG0494	nUDIX hydrolase
H3G96_RS05150	COG1459	type II secretion system
H3G96_RS05155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H3G96_RS05160	COG4969	Belongs to the N-Me-Phe pilin family
H3G96_RS05170	COG3023	N-Acetylmuramoyl-L-alanine amidase
H3G96_RS05175	COG3725	Membrane protein required for beta-lactamase induction
H3G96_RS05180	COG3940	Belongs to the glycosyl hydrolase 43 family
H3G96_RS05185	COG2211	Major facilitator Superfamily
H3G96_RS05190	COG1113	amino acid transport
H3G96_RS05195	COG2186	Transcriptional regulator
H3G96_RS05200	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H3G96_RS05205	COG0508	dehydrogenase complex catalyzes the overall conversion of
H3G96_RS05210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H3G96_RS05225	COG3064	Membrane
H3G96_RS05275	COG2132	Multicopper oxidase
H3G96_RS05280	COG4993	Dehydrogenase
H3G96_RS05295	COG0288	reversible hydration of carbon dioxide
H3G96_RS05300	COG1131	(ABC) transporter
H3G96_RS05305	COG0842	Transport permease protein
H3G96_RS05310	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS05315	COG0726	polysaccharide deacetylase
H3G96_RS05335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H3G96_RS05340	COG0617	tRNA 3'-terminal CCA addition
H3G96_RS05360	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H3G96_RS05365	COG1643	Atp-dependent helicase
H3G96_RS05460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H3G96_RS05470	COG1120	ATPase activity
H3G96_RS05475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H3G96_RS05480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3G96_RS05500	COG2860	membrane
H3G96_RS05520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H3G96_RS05525	COG3835	regulator
H3G96_RS05540	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
H3G96_RS05545	COG0024	Methionine aminopeptidase
H3G96_RS05570	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H3G96_RS05580	COG0575	Belongs to the CDS family
H3G96_RS05585	COG0750	zinc metalloprotease
H3G96_RS05595	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
H3G96_RS05635	COG1982	Orn Lys Arg decarboxylase major
H3G96_RS05640	COG0346	lactoylglutathione lyase activity
H3G96_RS05650	COG4568	rho-dependent transcription termination
H3G96_RS05665	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H3G96_RS05670	COG3015	lipoprotein NlpE involved in copper resistance
H3G96_RS05675	COG0791	NLP P60 protein
H3G96_RS05685	COG1720	tRNA m6t6A37 methyltransferase activity
H3G96_RS05695	COG1464	Belongs to the NlpA lipoprotein family
H3G96_RS05700	COG2011	ABC-type metal ion transport system permease component
H3G96_RS05710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H3G96_RS05745	COG0656	L-ascorbic acid biosynthetic process
H3G96_RS05750	COG0583	DNA-binding transcription factor activity
H3G96_RS05755	COG2814	Major facilitator Superfamily
H3G96_RS05765	COG2226	methyltransferase
H3G96_RS05770	COG1388	LysM domain
H3G96_RS05770	COG0741	lytic transglycosylase activity
H3G96_RS05780	COG2226	methyltransferase
H3G96_RS05790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H3G96_RS05800	COG0583	DNA-binding transcription factor activity
H3G96_RS05810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H3G96_RS05815	COG1960	acyl-CoA dehydrogenase activity
H3G96_RS05825	COG0121	glutamine amidotransferase
H3G96_RS05830	COG3034	peptidoglycan biosynthetic process
H3G96_RS05845	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H3G96_RS05850	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H3G96_RS05865	COG2991	Protein conserved in bacteria
H3G96_RS05880	COG0454	-acetyltransferase
H3G96_RS05885	COG2195	Cleaves the N-terminal amino acid of tripeptides
H3G96_RS05905	COG1802	Transcriptional regulator
H3G96_RS05910	COG1113	amino acid transport
H3G96_RS05915	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H3G96_RS05920	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS05925	COG0579	oxidoreductase
H3G96_RS05940	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H3G96_RS05945	COG0625	glutathione transferase activity
H3G96_RS05950	COG3775	system Galactitol-specific IIC component
H3G96_RS05955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H3G96_RS05960	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS05965	COG1070	Carbohydrate kinase
H3G96_RS05985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H3G96_RS05990	COG0508	dehydrogenase complex catalyzes the overall conversion of
H3G96_RS05995	COG0022	dehydrogenase e1 component
H3G96_RS06000	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H3G96_RS06060	COG1192	Involved in chromosome partitioning
H3G96_RS06065	COG0582	viral genome integration into host DNA
H3G96_RS06090	COG0791	NLP P60 protein
H3G96_RS06110	COG3639	organic phosphonate transmembrane transporter activity
H3G96_RS06120	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H3G96_RS06145	COG3188	usher protein
H3G96_RS06160	COG0765	amino acid transport
H3G96_RS06165	COG0765	amino acid transport
H3G96_RS06170	COG1126	abc transporter atp-binding protein
H3G96_RS06175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3G96_RS06215	COG4302	ethanolamine ammonia-lyase activity
H3G96_RS06220	COG4303	Ethanolamine ammonia lyase large subunit
H3G96_RS06240	COG2040	homocysteine
H3G96_RS06245	COG4521	taurine ABC transporter
H3G96_RS06250	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H3G96_RS06255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H3G96_RS06260	COG2175	clavaminate synthase activity
H3G96_RS06270	COG0113	porphobilinogen synthase activity
H3G96_RS06275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H3G96_RS06280	COG1335	isochorismatase
H3G96_RS06285	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H3G96_RS06325	COG1785	Belongs to the alkaline phosphatase family
H3G96_RS06335	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H3G96_RS06345	COG3416	Protein conserved in bacteria
H3G96_RS06350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H3G96_RS06360	COG4126	flavin adenine dinucleotide binding
H3G96_RS06375	COG1940	carbohydrate kinase activity
H3G96_RS06380	COG0419	ATPase involved in DNA repair
H3G96_RS06385	COG0420	3'-5' exonuclease activity
H3G96_RS06410	COG0366	Alpha amylase catalytic
H3G96_RS06415	COG0583	DNA-binding transcription factor activity
H3G96_RS06420	COG1335	isochorismatase
H3G96_RS06430	COG1228	amidohydrolase
H3G96_RS06440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H3G96_RS06455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS06465	COG0450	alkyl hydroperoxide reductase
H3G96_RS06490	COG1862	Preprotein translocase
H3G96_RS06495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H3G96_RS06500	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H3G96_RS06520	COG4238	major outer membrane lipoprotein
H3G96_RS06530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H3G96_RS06530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H3G96_RS06550	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H3G96_RS06555	COG0667	Aldo Keto reductase
H3G96_RS06565	COG0142	geranyltranstransferase activity
H3G96_RS06585	COG0693	protein deglycase activity
H3G96_RS06590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H3G96_RS06600	COG2814	Major facilitator Superfamily
H3G96_RS06605	COG0673	inositol 2-dehydrogenase activity
H3G96_RS06620	COG1053	succinate dehydrogenase
H3G96_RS06630	COG1053	succinate dehydrogenase
H3G96_RS06635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H3G96_RS06640	COG1414	Transcriptional regulator
H3G96_RS06655	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H3G96_RS06660	COG1845	cytochrome c oxidase, subunit III
H3G96_RS06665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H3G96_RS06670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H3G96_RS06675	COG2223	nitrite transmembrane transporter activity
H3G96_RS06680	COG3056	Lipoprotein
H3G96_RS06685	COG0271	Belongs to the BolA IbaG family
H3G96_RS06705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H3G96_RS06710	COG0776	regulation of translation
H3G96_RS06715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H3G96_RS06720	COG1555	photosystem II stabilization
H3G96_RS06725	COG0824	Thioesterase
H3G96_RS06735	COG4533	DNA binding
H3G96_RS06750	COG1522	sequence-specific DNA binding
H3G96_RS06755	COG1132	(ABC) transporter
H3G96_RS06760	COG1132	(ABC) transporter
H3G96_RS06765	COG0347	Belongs to the P(II) protein family
H3G96_RS06770	COG0004	ammonium transporteR
H3G96_RS06775	COG1946	Acyl-CoA thioesterase
H3G96_RS06780	COG3126	Type III secretion system lipoprotein chaperone (YscW)
H3G96_RS06785	COG3695	enzyme binding
H3G96_RS06815	COG2364	Membrane
H3G96_RS06830	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H3G96_RS06840	COG2182	Extracellular solute-binding protein
H3G96_RS06845	COG1175	transmembrane transport
H3G96_RS06850	COG3833	ABC-type maltose transport systems, permease component
H3G96_RS06855	COG3867	Arabinogalactan endo-beta-1,4-galactanase
H3G96_RS06860	COG1874	Beta-galactosidase
H3G96_RS06910	COG0110	maltose O-acetyltransferase activity
H3G96_RS06925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H3G96_RS06930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H3G96_RS06940	COG3039	Transposase
H3G96_RS06950	COG1196	nuclear chromosome segregation
H3G96_RS06950	COG3264	Mechanosensitive ion channel
H3G96_RS06955	COG5464	transposase or invertase
H3G96_RS06965	COG3923	Primosomal replication protein n
H3G96_RS06970	COG2832	Protein of unknown function (DUF454)
H3G96_RS07010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H3G96_RS07015	COG4651	solute:proton antiporter activity
H3G96_RS07015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H3G96_RS07020	COG2223	nitrite transmembrane transporter activity
H3G96_RS07030	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H3G96_RS07035	COG3735	TraB family
H3G96_RS07050	COG1585	Membrane protein implicated in regulation of membrane protease activity
H3G96_RS07055	COG0330	HflC and HflK could
H3G96_RS07060	COG4619	ABC transporter
H3G96_RS07065	COG0390	transport system, permease component
H3G96_RS07070	COG3118	belongs to the thioredoxin family
H3G96_RS07075	COG0300	oxidoreductase activity
H3G96_RS07080	COG2755	lipolytic protein G-D-S-L family
H3G96_RS07085	COG4181	ATPase activity
H3G96_RS07090	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H3G96_RS07110	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H3G96_RS07115	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H3G96_RS07130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H3G96_RS07140	COG2501	S4 domain
H3G96_RS07190	COG3539	Fimbrial protein
H3G96_RS07195	COG3121	Chaperone
H3G96_RS07200	COG3188	usher protein
H3G96_RS07215	COG1560	Kdo2-lipid A biosynthetic process
H3G96_RS07225	COG3710	Transcriptional regulator
H3G96_RS07230	COG0531	amino acid
H3G96_RS07235	COG1982	Orn Lys Arg decarboxylase major
H3G96_RS07240	COG3104	oligopeptide transport
H3G96_RS07270	COG0673	inositol 2-dehydrogenase activity
H3G96_RS07285	COG1129	ABC transporter
H3G96_RS07290	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS07335	COG1566	PFAM secretion protein HlyD family protein
H3G96_RS07340	COG1120	ATPase activity
H3G96_RS07345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3G96_RS07375	COG1473	amidohydrolase
H3G96_RS07380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3G96_RS07385	COG0667	Aldo Keto reductase
H3G96_RS07430	COG0531	amino acid
H3G96_RS07440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H3G96_RS07445	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS07460	COG1113	amino acid transport
H3G96_RS07465	COG2211	Major facilitator Superfamily
H3G96_RS07475	COG0673	inositol 2-dehydrogenase activity
H3G96_RS07485	COG2771	luxR family
H3G96_RS07500	COG3188	usher protein
H3G96_RS07530	COG0668	transmembrane transport
H3G96_RS07535	COG0477	Major facilitator Superfamily
H3G96_RS07550	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H3G96_RS07550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H3G96_RS07555	COG2222	sugar isomerase
H3G96_RS07560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H3G96_RS07565	COG3716	PTS system mannose fructose sorbose family IID component
H3G96_RS07575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H3G96_RS07585	COG0778	Nitroreductase
H3G96_RS07590	COG2315	Protein conserved in bacteria
H3G96_RS07635	COG3698	Phosphodiester glycosidase
H3G96_RS07645	COG0697	spore germination
H3G96_RS07660	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
H3G96_RS07665	COG0765	amino acid transport
H3G96_RS07670	COG4215	(ABC) transporter
H3G96_RS07680	COG4221	oxidoreductase activity
H3G96_RS07685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H3G96_RS07690	COG4608	Belongs to the ABC transporter superfamily
H3G96_RS07695	COG0444	Belongs to the ABC transporter superfamily
H3G96_RS07700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H3G96_RS07705	COG0601	transmembrane transport
H3G96_RS07710	COG0747	negative chemotaxis
H3G96_RS07745	COG0668	transmembrane transport
H3G96_RS07750	COG0583	DNA-binding transcription factor activity
H3G96_RS07760	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS07770	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS07775	COG1129	ABC transporter
H3G96_RS07785	COG1879	ABC-type sugar transport system periplasmic component
H3G96_RS07790	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H3G96_RS07795	COG2390	Transcriptional regulator
H3G96_RS07800	COG3959	Transketolase, thiamine diphosphate binding domain
H3G96_RS07805	COG3958	Transketolase
H3G96_RS07810	COG2977	Belongs to the P-Pant transferase superfamily
H3G96_RS07815	COG4771	TonB-dependent receptor
H3G96_RS07820	COG2382	esterase
H3G96_RS07825	COG3251	PFAM MbtH domain protein
H3G96_RS07830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H3G96_RS07830	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H3G96_RS07835	COG1120	ATPase activity
H3G96_RS07840	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3G96_RS07845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3G96_RS07855	COG4592	Periplasmic binding protein
H3G96_RS07860	COG1169	isochorismate synthase
H3G96_RS07865	COG1021	2,3-dihydroxybenzoate-AMP ligase
H3G96_RS07870	COG1535	isochorismatase
H3G96_RS07870	COG3433	isochorismatase activity
H3G96_RS07875	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS07885	COG1966	Carbon starvation protein
H3G96_RS07890	COG2879	small protein
H3G96_RS07905	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS07910	COG0371	Dehydrogenase
H3G96_RS07915	COG1129	ABC transporter
H3G96_RS07920	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS07950	COG2271	Major facilitator Superfamily
H3G96_RS07955	COG0483	inositol monophosphate 1-phosphatase activity
H3G96_RS07965	COG0402	S-adenosylhomocysteine deaminase activity
H3G96_RS07975	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H3G96_RS07990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H3G96_RS08000	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS08005	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS08010	COG1129	ABC transporter
H3G96_RS08035	COG0436	Aminotransferase
H3G96_RS08040	COG1475	DNA binding
H3G96_RS08045	COG3969	phosphoadenosine phosphosulfate
H3G96_RS08050	COG0583	DNA-binding transcription factor activity
H3G96_RS08055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H3G96_RS08075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H3G96_RS08080	COG3719	Belongs to the RNase T2 family
H3G96_RS08085	COG3069	C4-dicarboxylate transmembrane transporter activity
H3G96_RS08105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H3G96_RS08120	COG0583	DNA-binding transcription factor activity
H3G96_RS08135	COG1686	Belongs to the peptidase S11 family
H3G96_RS08140	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H3G96_RS08145	COG0772	Belongs to the SEDS family
H3G96_RS08150	COG0768	penicillin binding
H3G96_RS08160	COG0799	negative regulation of ribosome biogenesis
H3G96_RS08175	COG1466	dna polymerase III delta subunit
H3G96_RS08190	COG2888	peptidyl-tyrosine sulfation
H3G96_RS08205	COG1126	abc transporter atp-binding protein
H3G96_RS08210	COG0765	amino acid transport
H3G96_RS08215	COG0765	amino acid transport
H3G96_RS08230	COG4535	Mg2 and Co2 transporter CorC
H3G96_RS08240	COG1702	phosphate starvation-inducible protein PhoH
H3G96_RS08250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H3G96_RS08295	COG0367	asparagine synthase
H3G96_RS08300	COG0647	UMP catabolic process
H3G96_RS08305	COG1940	carbohydrate kinase activity
H3G96_RS08305	COG1846	Transcriptional regulator
H3G96_RS08310	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H3G96_RS08350	COG0735	belongs to the Fur family
H3G96_RS08365	COG0596	Alpha beta hydrolase
H3G96_RS08375	COG0033	Phosphoglucomutase
H3G96_RS08385	COG0745	RESPONSE REGULATOR receiver
H3G96_RS08390	COG2205	protein histidine kinase activity
H3G96_RS08420	COG0415	Belongs to the DNA photolyase family
H3G96_RS08435	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H3G96_RS08440	COG1984	allophanate hydrolase subunit 2
H3G96_RS08475	COG2009	succinate dehydrogenase
H3G96_RS08480	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H3G96_RS08485	COG1053	succinate dehydrogenase
H3G96_RS08490	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H3G96_RS08495	COG0567	Dehydrogenase, E1 component
H3G96_RS08500	COG0508	dehydrogenase complex catalyzes the overall conversion of
H3G96_RS08510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H3G96_RS08515	COG1271	oxidase subunit
H3G96_RS08520	COG1294	oxidase, subunit
H3G96_RS08525	COG4890	Cyd operon protein YbgT
H3G96_RS08530	COG3790	cyd operon protein YbgE
H3G96_RS08535	COG0824	Thioesterase
H3G96_RS08540	COG0811	peptide transport
H3G96_RS08545	COG0848	biopolymer transport protein
H3G96_RS08550	COG3064	Membrane
H3G96_RS08560	COG2885	chlorophyll binding
H3G96_RS08565	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
H3G96_RS08605	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H3G96_RS08610	COG3201	nicotinamide mononucleotide transporter
H3G96_RS08625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H3G96_RS08635	COG2017	converts alpha-aldose to the beta-anomer
H3G96_RS08645	COG1085	galactose-1-phosphate uridylyltransferase
H3G96_RS08655	COG1119	ATPase activity
H3G96_RS08660	COG3585	molybdate ion transport
H3G96_RS08660	COG2005	Transcriptional regulator
H3G96_RS08670	COG0725	ABC transporter, periplasmic molybdate-binding protein
H3G96_RS08675	COG4149	molybdate abc transporter
H3G96_RS08680	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H3G96_RS08685	COG0561	phosphatase activity
H3G96_RS08710	COG2200	EAL domain
H3G96_RS08715	COG0789	Transcriptional regulator
H3G96_RS08750	COG4677	pectinesterase activity
H3G96_RS08790	COG1881	PFAM PEBP family protein
H3G96_RS08795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H3G96_RS08810	COG2226	methyltransferase
H3G96_RS08835	COG0642	Histidine kinase
H3G96_RS08840	COG0745	RESPONSE REGULATOR receiver
H3G96_RS08860	COG0521	Mo-molybdopterin cofactor biosynthetic process
H3G96_RS08870	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H3G96_RS08875	COG0314	molybdopterin synthase activity
H3G96_RS08880	COG0670	Belongs to the BI1 family
H3G96_RS08885	COG0392	lysyltransferase activity
H3G96_RS08890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H3G96_RS08895	COG3568	Endonuclease Exonuclease Phosphatase
H3G96_RS08905	COG0842	Transport permease protein
H3G96_RS08910	COG0842	Transport permease protein
H3G96_RS08915	COG1131	(ABC) transporter
H3G96_RS08920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H3G96_RS08925	COG1309	transcriptional regulator
H3G96_RS08930	COG0583	DNA-binding transcription factor activity
H3G96_RS08940	COG2271	Major facilitator Superfamily
H3G96_RS08945	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS08950	COG3959	Transketolase, thiamine diphosphate binding domain
H3G96_RS08955	COG3958	Transketolase
H3G96_RS08960	COG0513	Belongs to the DEAD box helicase family
H3G96_RS08965	COG1199	ATP-dependent helicase activity
H3G96_RS08970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H3G96_RS08980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H3G96_RS08990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H3G96_RS09000	COG0668	transmembrane transport
H3G96_RS09005	COG1126	abc transporter atp-binding protein
H3G96_RS09010	COG0765	amino acid transport
H3G96_RS09015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3G96_RS09030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H3G96_RS09035	COG2194	sulfuric ester hydrolase activity
H3G96_RS09045	COG1321	iron dependent repressor
H3G96_RS09050	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H3G96_RS09055	COG2723	6-phospho-beta-galactosidase activity
H3G96_RS09060	COG2188	Transcriptional regulator
H3G96_RS09065	COG1376	ErfK ybiS ycfS ynhG family protein
H3G96_RS09070	COG2365	Tyrosine phosphatase family
H3G96_RS09075	COG0488	(ABC) transporter
H3G96_RS09085	COG2271	Major facilitator Superfamily
H3G96_RS09090	COG1609	Transcriptional regulator
H3G96_RS09100	COG0561	phosphatase activity
H3G96_RS09105	COG1882	Formate acetyltransferase
H3G96_RS09110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H3G96_RS09115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H3G96_RS09120	COG0303	'Molybdopterin
H3G96_RS09135	COG0747	negative chemotaxis
H3G96_RS09155	COG2223	nitrite transmembrane transporter activity
H3G96_RS09165	COG2133	pyrroloquinoline quinone binding
H3G96_RS09170	COG0625	glutathione transferase activity
H3G96_RS09180	COG1686	Belongs to the peptidase S11 family
H3G96_RS09185	COG1349	DNA-binding transcription factor activity
H3G96_RS09190	COG0671	phosphoesterase, PA-phosphatase related
H3G96_RS09195	COG2814	Major facilitator Superfamily
H3G96_RS09200	COG0561	phosphatase activity
H3G96_RS09205	COG0738	Major facilitator superfamily
H3G96_RS09210	COG3226	Transcriptional regulator
H3G96_RS09215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H3G96_RS09220	COG3344	reverse transcriptase
H3G96_RS09245	COG4695	Portal protein
H3G96_RS09320	COG3039	Transposase
H3G96_RS09445	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H3G96_RS09450	COG3842	ATPase activity
H3G96_RS09455	COG1176	ABC-type spermidine putrescine transport system, permease component I
H3G96_RS09460	COG1177	transmembrane transport
H3G96_RS09475	COG0745	RESPONSE REGULATOR receiver
H3G96_RS09480	COG5002	protein histidine kinase activity
H3G96_RS09485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3G96_RS09490	COG4160	amino acid transport
H3G96_RS09495	COG4215	(ABC) transporter
H3G96_RS09500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3G96_RS09505	COG1126	abc transporter atp-binding protein
H3G96_RS09515	COG2203	Gaf domain
H3G96_RS09515	COG4251	negative regulation of phosphorylation
H3G96_RS09515	COG3706	GGDEF domain
H3G96_RS09515	COG5001	Diguanylate cyclase
H3G96_RS09520	COG3023	N-Acetylmuramoyl-L-alanine amidase
H3G96_RS09525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H3G96_RS09530	COG0702	epimerase
H3G96_RS09535	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
H3G96_RS09540	COG0028	Belongs to the TPP enzyme family
H3G96_RS09550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H3G96_RS09560	COG2431	L-lysine efflux transmembrane transporter activity
H3G96_RS09570	COG3593	DNA synthesis involved in DNA repair
H3G96_RS09575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H3G96_RS09585	COG1278	Cold shock
H3G96_RS09595	COG0542	response to heat
H3G96_RS09610	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H3G96_RS09615	COG4988	ABC transporter
H3G96_RS09620	COG0492	ferredoxin-NADP+ reductase activity
H3G96_RS09630	COG1674	ftsk spoiiie
H3G96_RS09630	COG1178	ABC-type Fe3 transport system permease component
H3G96_RS09640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H3G96_RS09650	COG0243	molybdopterin cofactor binding
H3G96_RS09655	COG0437	4 iron, 4 sulfur cluster binding
H3G96_RS09660	COG3302	dmso reductase anchor subunit
H3G96_RS09665	COG0477	Major facilitator Superfamily
H3G96_RS09670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H3G96_RS09675	COG1882	Formate acetyltransferase
H3G96_RS09680	COG2116	formate transmembrane transporter activity
H3G96_RS09685	COG1944	ATP diphosphatase activity
H3G96_RS09690	COG2323	membrane
H3G96_RS09710	COG0539	negative regulation of cytoplasmic translation
H3G96_RS09720	COG0658	competence protein
H3G96_RS09720	COG2333	competence protein COMEC
H3G96_RS09735	COG3214	Protein conserved in bacteria
H3G96_RS09750	COG3173	Aminoglycoside phosphotransferase
H3G96_RS09755	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H3G96_RS09760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H3G96_RS09770	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
H3G96_RS09780	COG2989	Protein conserved in bacteria
H3G96_RS09785	COG3108	Peptidase M15
H3G96_RS09790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H3G96_RS09795	COG1448	Aminotransferase
H3G96_RS09820	COG0814	amino acid
H3G96_RS09830	COG1473	amidohydrolase
H3G96_RS09840	COG0308	aminopeptidase N
H3G96_RS09850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H3G96_RS09855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H3G96_RS09860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H3G96_RS09865	COG0431	NADPH-dependent FMN reductase
H3G96_RS09880	COG3217	Mosc domain protein beta barrel domain protein
H3G96_RS09880	COG0633	Ferredoxin
H3G96_RS09890	COG0488	(ABC) transporter
H3G96_RS09895	COG2995	paraquat-inducible protein a
H3G96_RS09900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H3G96_RS09900	COG3008	intermembrane lipid transfer
H3G96_RS09905	COG3009	Protein conserved in bacteria
H3G96_RS09910	COG3130	regulation of translation
H3G96_RS09920	COG1067	ATP-dependent peptidase activity
H3G96_RS09940	COG3070	regulator of competence-specific genes
H3G96_RS09945	COG1289	transmembrane transporter activity
H3G96_RS09950	COG3304	Inner membrane component domain
H3G96_RS09955	COG0210	DNA helicase
H3G96_RS09965	COG1832	CoA-binding protein
H3G96_RS09980	COG1881	PFAM PEBP family protein
H3G96_RS09985	COG2207	Transcriptional regulator
H3G96_RS10000	COG0670	Belongs to the BI1 family
H3G96_RS10025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H3G96_RS10030	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS10035	COG4638	Rieske (2fe-2S)
H3G96_RS10040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H3G96_RS10045	COG0473	3-isopropylmalate dehydrogenase activity
H3G96_RS10050	COG0583	DNA-binding transcription factor activity
H3G96_RS10055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H3G96_RS10060	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS10065	COG1917	Cupin 2, conserved barrel domain protein
H3G96_RS10065	COG1396	sequence-specific DNA binding
H3G96_RS10070	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H3G96_RS10075	COG0174	glutamine synthetase
H3G96_RS10080	COG0531	amino acid
H3G96_RS10095	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS10110	COG4974	Belongs to the 'phage' integrase family
H3G96_RS10185	COG4695	Portal protein
H3G96_RS10350	COG3729	General stress protein
H3G96_RS10360	COG2233	PERMEase
H3G96_RS10395	COG1309	transcriptional regulator
H3G96_RS10410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H3G96_RS10420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H3G96_RS10440	COG1702	phosphate starvation-inducible protein PhoH
H3G96_RS10445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H3G96_RS10455	COG1335	isochorismatase
H3G96_RS10465	COG0583	DNA-binding transcription factor activity
H3G96_RS10490	COG3381	protein complex oligomerization
H3G96_RS10525	COG5645	(Lipo)protein
H3G96_RS10540	COG1560	Kdo2-lipid A biosynthetic process
H3G96_RS10585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H3G96_RS10605	COG2814	Major facilitator Superfamily
H3G96_RS10610	COG0583	DNA-binding transcription factor activity
H3G96_RS10615	COG1530	ribonuclease E activity
H3G96_RS10635	COG1399	metal-binding, possibly nucleic acid-binding protein
H3G96_RS10655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H3G96_RS10670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H3G96_RS10675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H3G96_RS10680	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H3G96_RS10690	COG0470	DNA polymerase III
H3G96_RS10695	COG0084	hydrolase, TatD family'
H3G96_RS10705	COG0537	adenosine 5'-monophosphoramidase activity
H3G96_RS10710	COG5633	Lipoprotein
H3G96_RS10735	COG1252	NADH dehydrogenase
H3G96_RS10740	COG3134	Outer membrane lipoprotein
H3G96_RS10755	COG1309	transcriptional regulator
H3G96_RS10770	COG1376	ErfK ybiS ycfS ynhG family protein
H3G96_RS10770	COG1388	LysM domain
H3G96_RS10775	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H3G96_RS10785	COG4591	ABC-type transport system involved in lipoprotein release permease component
H3G96_RS10795	COG4591	ABC-type transport system involved in lipoprotein release permease component
H3G96_RS10805	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H3G96_RS10815	COG0318	PFAM AMP-dependent synthetase and ligase
H3G96_RS10830	COG1177	transmembrane transport
H3G96_RS10850	COG2850	peptidyl-arginine hydroxylation
H3G96_RS10855	COG2205	protein histidine kinase activity
H3G96_RS10875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H3G96_RS10895	COG1187	pseudouridine synthase activity
H3G96_RS10900	COG0538	isocitrate dehydrogenase activity
H3G96_RS10905	COG0582	viral genome integration into host DNA
H3G96_RS10915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H3G96_RS10935	COG1396	sequence-specific DNA binding
H3G96_RS10980	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H3G96_RS10985	COG3344	reverse transcriptase
H3G96_RS11005	COG1403	HNH endonuclease
H3G96_RS11030	COG3772	lysozyme
H3G96_RS11075	COG4626	Terminase
H3G96_RS11075	COG1802	Transcriptional regulator
H3G96_RS11090	COG0616	signal peptide processing
H3G96_RS11175	COG0538	isocitrate dehydrogenase activity
H3G96_RS11180	COG0640	Transcriptional regulator
H3G96_RS11200	COG3813	Protein conserved in bacteria
H3G96_RS11205	COG1063	alcohol dehydrogenase
H3G96_RS11210	COG3729	General stress protein
H3G96_RS11215	COG3685	Protein conserved in bacteria
H3G96_RS11220	COG3685	Protein conserved in bacteria
H3G96_RS11225	COG3546	catalase activity
H3G96_RS11230	COG1271	oxidase subunit
H3G96_RS11235	COG1294	oxidase, subunit
H3G96_RS11265	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H3G96_RS11270	COG0583	DNA-binding transcription factor activity
H3G96_RS11275	COG3706	GGDEF domain
H3G96_RS11280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H3G96_RS11290	COG1560	Kdo2-lipid A biosynthetic process
H3G96_RS11300	COG3182	Iron-regulated membrane protein
H3G96_RS11320	COG2199	diguanylate cyclase activity
H3G96_RS11320	COG2203	Gaf domain
H3G96_RS11325	COG3042	response to heat
H3G96_RS11330	COG3189	MarR family transcriptional regulator
H3G96_RS11335	COG1683	Conserved Protein
H3G96_RS11340	COG0504	CTP synthase activity
H3G96_RS11345	COG2807	transmembrane transport
H3G96_RS11350	COG2207	Transcriptional regulator
H3G96_RS11360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H3G96_RS11365	COG0859	PFAM glycosyl transferase family 9
H3G96_RS11375	COG3344	reverse transcriptase
H3G96_RS11380	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H3G96_RS11385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H3G96_RS11390	COG0583	DNA-binding transcription factor activity
H3G96_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS11420	COG0386	Belongs to the glutathione peroxidase family
H3G96_RS11435	COG2766	serine protein kinase
H3G96_RS11440	COG3713	MltA-interacting MipA family protein
H3G96_RS11465	COG3139	Protein of unknown function (DUF1315)
H3G96_RS11480	COG1063	alcohol dehydrogenase
H3G96_RS11485	COG2271	Major facilitator Superfamily
H3G96_RS11490	COG1063	alcohol dehydrogenase
H3G96_RS11495	COG0191	fructose-bisphosphate aldolase activity
H3G96_RS11500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H3G96_RS11505	COG0667	Aldo Keto reductase
H3G96_RS11510	COG1349	DNA-binding transcription factor activity
H3G96_RS11515	COG2814	Major facilitator Superfamily
H3G96_RS11520	COG1335	isochorismatase
H3G96_RS11525	COG0252	asparaginase activity
H3G96_RS11530	COG0616	signal peptide processing
H3G96_RS11535	COG0778	Nitroreductase
H3G96_RS11550	COG0709	Synthesizes selenophosphate from selenide and ATP
H3G96_RS11555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H3G96_RS11560	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS11560	COG3321	synthase
H3G96_RS11560	COG0604	alcohol dehydrogenase
H3G96_RS11565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H3G96_RS11570	COG0494	nUDIX hydrolase
H3G96_RS11575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H3G96_RS11580	COG2897	thiosulfate sulfurtransferase activity
H3G96_RS11585	COG4136	ATPase activity
H3G96_RS11590	COG4135	transport system, permease component
H3G96_RS11595	COG4134	Bacterial extracellular solute-binding protein
H3G96_RS11600	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H3G96_RS11605	COG0398	Pfam SNARE associated Golgi protein
H3G96_RS11610	COG0398	Pfam SNARE associated Golgi protein
H3G96_RS11615	COG0708	Exodeoxyribonuclease III
H3G96_RS11625	COG3138	arginine N-succinyltransferase
H3G96_RS11635	COG3724	N-succinylarginine dihydrolase activity
H3G96_RS11645	COG3678	ATP-independent chaperone mediated protein folding
H3G96_RS11650	COG0322	excinuclease ABC activity
H3G96_RS11660	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H3G96_RS11665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS11675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS11680	COG1447	Phosphotransferase system cellobiose-specific component IIA
H3G96_RS11685	COG2169	Transcriptional regulator
H3G96_RS11685	COG1917	Cupin 2, conserved barrel domain protein
H3G96_RS11690	COG1486	melibiose metabolic process
H3G96_RS11700	COG0753	catalase activity
H3G96_RS11710	COG1823	symporter activity
H3G96_RS11715	COG1988	membrane-bound metal-dependent
H3G96_RS11720	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS11725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H3G96_RS11755	COG0727	PFAM Uncharacterised protein family (UPF0153)
H3G96_RS11760	COG3047	cAMP biosynthetic process
H3G96_RS11770	COG4774	siderophore transport
H3G96_RS11825	COG0134	indole-3-glycerol-phosphate synthase activity
H3G96_RS11825	COG0135	phosphoribosylanthranilate isomerase activity
H3G96_RS11830	COG0512	Glutamine amidotransferase of anthranilate synthase
H3G96_RS11830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H3G96_RS11835	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H3G96_RS11845	COG0009	L-threonylcarbamoyladenylate synthase
H3G96_RS11855	COG0583	DNA-binding transcription factor activity
H3G96_RS11865	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H3G96_RS11870	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS11880	COG0616	signal peptide processing
H3G96_RS11905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H3G96_RS11915	COG0671	phosphoesterase, PA-phosphatase related
H3G96_RS11920	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
H3G96_RS11925	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H3G96_RS11935	COG0023	Translation Initiation Factor
H3G96_RS11945	COG1349	DNA-binding transcription factor activity
H3G96_RS11960	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H3G96_RS11960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H3G96_RS11965	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H3G96_RS11975	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H3G96_RS11990	COG4171	peptide transport system, permease
H3G96_RS12105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H3G96_RS12170	COG3344	reverse transcriptase
H3G96_RS12175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H3G96_RS12180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H3G96_RS12190	COG2135	peptidase activity
H3G96_RS12205	COG0702	epimerase
H3G96_RS12220	COG1473	amidohydrolase
H3G96_RS12230	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H3G96_RS12235	COG1842	Phage shock protein A
H3G96_RS12245	COG1983	PspC domain protein
H3G96_RS12255	COG3106	COG3106 Predicted ATPase
H3G96_RS12265	COG0583	DNA-binding transcription factor activity
H3G96_RS12270	COG1486	melibiose metabolic process
H3G96_RS12280	COG3180	Ammonia monooxygenase
H3G96_RS12285	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H3G96_RS12290	COG4948	Mandelate Racemase Muconate Lactonizing
H3G96_RS12295	COG2866	Carboxypeptidase
H3G96_RS12305	COG4166	transmembrane transport
H3G96_RS12335	COG0656	L-ascorbic acid biosynthetic process
H3G96_RS12355	COG0583	DNA-binding transcription factor activity
H3G96_RS12360	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS12365	COG1078	dGTPase activity
H3G96_RS12370	COG0693	protein deglycase activity
H3G96_RS12375	COG0582	viral genome integration into host DNA
H3G96_RS12480	COG0484	heat shock protein binding
H3G96_RS12490	COG3772	lysozyme
H3G96_RS12510	COG1783	phage Terminase large subunit
H3G96_RS12515	COG3567	Phage-associated protein, HI1409 family
H3G96_RS12585	COG1196	nuclear chromosome segregation
H3G96_RS12585	COG0741	lytic transglycosylase activity
H3G96_RS12585	COG0739	heme binding
H3G96_RS12705	COG2885	chlorophyll binding
H3G96_RS12800	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS12805	COG1309	transcriptional regulator
H3G96_RS12810	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS12830	COG0583	DNA-binding transcription factor activity
H3G96_RS12860	COG0604	alcohol dehydrogenase
H3G96_RS12865	COG0436	Aminotransferase
H3G96_RS12880	COG2011	ABC-type metal ion transport system permease component
H3G96_RS12885	COG1448	Aminotransferase
H3G96_RS12895	COG1522	sequence-specific DNA binding
H3G96_RS12900	COG1113	amino acid transport
H3G96_RS12915	COG0673	inositol 2-dehydrogenase activity
H3G96_RS12920	COG1349	DNA-binding transcription factor activity
H3G96_RS12930	COG0513	Belongs to the DEAD box helicase family
H3G96_RS12940	COG0589	response to stress
H3G96_RS12950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H3G96_RS12955	COG0674	pyruvate-flavodoxin oxidoreductase activity
H3G96_RS12955	COG1013	pyruvate-flavodoxin oxidoreductase activity
H3G96_RS12955	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H3G96_RS12955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H3G96_RS12960	COG3042	response to heat
H3G96_RS12965	COG3187	Heat shock protein
H3G96_RS12970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H3G96_RS12975	COG0586	Pfam SNARE associated Golgi protein
H3G96_RS12980	COG2911	Protein conserved in bacteria
H3G96_RS12990	COG3784	Protein of unknown function (DUF1318)
H3G96_RS12995	COG2207	Transcriptional regulator
H3G96_RS13000	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS13020	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS13020	COG2030	dehydratase
H3G96_RS13025	COG3396	Phenylacetate-CoA oxygenase
H3G96_RS13030	COG3460	Phenylacetate-CoA oxygenase
H3G96_RS13035	COG3396	Phenylacetate-CoA oxygenase
H3G96_RS13040	COG2151	metal-sulfur cluster biosynthetic enzyme
H3G96_RS13045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H3G96_RS13050	COG1024	Enoyl-CoA hydratase
H3G96_RS13055	COG1024	Enoyl-CoA hydratase
H3G96_RS13060	COG1250	3-hydroxyacyl-CoA dehydrogenase
H3G96_RS13065	COG2050	protein possibly involved in aromatic compounds catabolism
H3G96_RS13070	COG0183	Belongs to the thiolase family
H3G96_RS13075	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H3G96_RS13080	COG3327	negative regulation of DNA-templated transcription, initiation
H3G96_RS13085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H3G96_RS13100	COG1643	Atp-dependent helicase
H3G96_RS13105	COG4122	O-methyltransferase activity
H3G96_RS13130	COG0583	DNA-binding transcription factor activity
H3G96_RS13135	COG0667	Aldo Keto reductase
H3G96_RS13140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H3G96_RS13150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H3G96_RS13155	COG3138	arginine N-succinyltransferase
H3G96_RS13160	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS13165	COG3724	N-succinylarginine dihydrolase activity
H3G96_RS13170	COG2988	succinylglutamate desuccinylase activity
H3G96_RS13175	COG1113	amino acid transport
H3G96_RS13180	COG0477	Major facilitator Superfamily
H3G96_RS13185	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H3G96_RS13195	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS13200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H3G96_RS13205	COG0401	homolog of Blt101
H3G96_RS13210	COG5562	phage envelope protein
H3G96_RS13215	COG0425	Belongs to the sulfur carrier protein TusA family
H3G96_RS13220	COG2391	methyltransferase activity
H3G96_RS13245	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H3G96_RS13250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H3G96_RS13250	COG1263	PTS System
H3G96_RS13255	COG1609	Transcriptional regulator
H3G96_RS13260	COG5339	Protein conserved in bacteria
H3G96_RS13265	COG1482	cell wall glycoprotein biosynthetic process
H3G96_RS13270	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H3G96_RS13270	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H3G96_RS13275	COG0114	fumarate hydratase activity
H3G96_RS13285	COG2205	protein histidine kinase activity
H3G96_RS13295	COG0745	RESPONSE REGULATOR receiver
H3G96_RS13300	COG3136	membrane protein required for alginate biosynthesis
H3G96_RS13310	COG0531	amino acid
H3G96_RS13325	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H3G96_RS13330	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H3G96_RS13345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H3G96_RS13360	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H3G96_RS13365	COG1473	amidohydrolase
H3G96_RS13375	COG0583	DNA-binding transcription factor activity
H3G96_RS13380	COG2840	Smr protein MutS2
H3G96_RS13385	COG1414	Transcriptional regulator
H3G96_RS13395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H3G96_RS13400	COG0183	Belongs to the thiolase family
H3G96_RS13410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H3G96_RS13415	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H3G96_RS13425	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H3G96_RS13425	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H3G96_RS13445	COG4565	transcriptional regulatory protein
H3G96_RS13450	COG3290	protein histidine kinase activity
H3G96_RS13475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H3G96_RS13485	COG0679	Auxin Efflux Carrier
H3G96_RS13515	COG0628	permease
H3G96_RS13535	COG3591	Belongs to the peptidase S1B family
H3G96_RS13545	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H3G96_RS13550	COG2814	Major facilitator Superfamily
H3G96_RS13555	COG0583	DNA-binding transcription factor activity
H3G96_RS13560	COG1940	carbohydrate kinase activity
H3G96_RS13565	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H3G96_RS13580	COG0589	response to stress
H3G96_RS13585	COG1802	Transcriptional regulator
H3G96_RS13590	COG4221	oxidoreductase activity
H3G96_RS13605	COG2207	Transcriptional regulator
H3G96_RS13610	COG2135	peptidase activity
H3G96_RS13625	COG2197	response regulator
H3G96_RS13640	COG0071	Belongs to the small heat shock protein (HSP20) family
H3G96_RS13645	COG1546	Belongs to the CinA family
H3G96_RS13650	COG2200	EAL domain
H3G96_RS13665	COG2207	Transcriptional regulator
H3G96_RS13665	COG3708	Transcriptional regulator
H3G96_RS13670	COG2610	gluconate transmembrane transporter activity
H3G96_RS13675	COG3622	Belongs to the hyi family
H3G96_RS13680	COG0235	Class ii aldolase
H3G96_RS13685	COG3395	kinase activity
H3G96_RS13690	COG2084	Dehydrogenase
H3G96_RS13695	COG1349	DNA-binding transcription factor activity
H3G96_RS13710	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H3G96_RS13715	COG2223	nitrite transmembrane transporter activity
H3G96_RS13750	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H3G96_RS13755	COG0683	leucine binding
H3G96_RS13770	COG1129	ABC transporter
H3G96_RS13775	COG0410	ABC transporter
H3G96_RS13785	COG2814	Major facilitator Superfamily
H3G96_RS13790	COG0697	spore germination
H3G96_RS13800	COG4977	sequence-specific DNA binding
H3G96_RS13830	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS13835	COG2731	YhcH YjgK YiaL family protein
H3G96_RS13850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H3G96_RS13860	COG3395	kinase activity
H3G96_RS13865	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H3G96_RS13870	COG1349	DNA-binding transcription factor activity
H3G96_RS13875	COG0039	L-malate dehydrogenase activity
H3G96_RS13885	COG0583	DNA-binding transcription factor activity
H3G96_RS13890	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS13905	COG2199	diguanylate cyclase activity
H3G96_RS13975	COG0477	Major facilitator Superfamily
H3G96_RS13985	COG2070	2-Nitropropane dioxygenase
H3G96_RS13990	COG2011	ABC-type metal ion transport system permease component
H3G96_RS14010	COG4628	conserved protein (DUF2132)
H3G96_RS14025	COG2207	Transcriptional regulator
H3G96_RS14055	COG2233	PERMEase
H3G96_RS14060	COG3648	Uricase
H3G96_RS14060	COG3195	allantoin biosynthetic process
H3G96_RS14065	COG2351	hydroxyisourate hydrolase activity
H3G96_RS14070	COG1396	sequence-specific DNA binding
H3G96_RS14075	COG3550	peptidyl-serine autophosphorylation
H3G96_RS14080	COG1649	PFAM Uncharacterised BCR, COG1649
H3G96_RS14090	COG3188	usher protein
H3G96_RS14125	COG3300	MHYT domain
H3G96_RS14125	COG5001	Diguanylate cyclase
H3G96_RS14130	COG2819	hydrolase of the alpha beta superfamily
H3G96_RS14145	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS14145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS14150	COG2814	Major facilitator Superfamily
H3G96_RS14160	COG1263	PTS System
H3G96_RS14160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H3G96_RS14165	COG2186	Transcriptional regulator
H3G96_RS14185	COG3835	regulator
H3G96_RS14190	COG1929	Belongs to the glycerate kinase type-1 family
H3G96_RS14235	COG0738	Major facilitator superfamily
H3G96_RS14240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H3G96_RS14245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H3G96_RS14250	COG1349	DNA-binding transcription factor activity
H3G96_RS14265	COG1349	DNA-binding transcription factor activity
H3G96_RS14270	COG4977	sequence-specific DNA binding
H3G96_RS14290	COG4977	sequence-specific DNA binding
H3G96_RS14310	COG0667	Aldo Keto reductase
H3G96_RS14320	COG0667	Aldo Keto reductase
H3G96_RS14325	COG0667	Aldo Keto reductase
H3G96_RS14335	COG0456	acetyltransferase
H3G96_RS14335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H3G96_RS14360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H3G96_RS14360	COG0426	domain, Protein
H3G96_RS14375	COG1652	LysM domain
H3G96_RS14405	COG1609	Transcriptional regulator
H3G96_RS14415	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS14430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H3G96_RS14440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H3G96_RS14445	COG0583	DNA-binding transcription factor activity
H3G96_RS14450	COG0583	DNA-binding transcription factor activity
H3G96_RS14465	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H3G96_RS14465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H3G96_RS14465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H3G96_RS14470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H3G96_RS14480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H3G96_RS14485	COG3037	sugar-specific permease SgaT UlaA
H3G96_RS14495	COG3039	Transposase
H3G96_RS14505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS14510	COG1609	Transcriptional regulator
H3G96_RS14520	COG2223	nitrite transmembrane transporter activity
H3G96_RS14550	COG0477	Major facilitator Superfamily
H3G96_RS14555	COG4529	Protein conserved in bacteria
H3G96_RS14560	COG1902	pentaerythritol trinitrate reductase activity
H3G96_RS14570	COG0583	DNA-binding transcription factor activity
H3G96_RS14575	COG2070	2-Nitropropane dioxygenase
H3G96_RS14585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H3G96_RS14595	COG0765	amino acid transport
H3G96_RS14665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H3G96_RS14695	COG1335	isochorismatase
H3G96_RS14700	COG0406	alpha-ribazole phosphatase activity
H3G96_RS14735	COG1953	Uracil, thiamine, allantoin
H3G96_RS14740	COG0402	S-adenosylhomocysteine deaminase activity
H3G96_RS14745	COG3706	GGDEF domain
H3G96_RS14750	COG1609	Transcriptional regulator
H3G96_RS14760	COG0673	inositol 2-dehydrogenase activity
H3G96_RS14775	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H3G96_RS14780	COG1116	anion transmembrane transporter activity
H3G96_RS14785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H3G96_RS14790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H3G96_RS14795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H3G96_RS14800	COG0076	glutamate decarboxylase activity
H3G96_RS14815	COG2205	protein histidine kinase activity
H3G96_RS14825	COG0596	Alpha beta hydrolase
H3G96_RS14865	COG0519	Catalyzes the synthesis of GMP from XMP
H3G96_RS14865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H3G96_RS14885	COG0583	DNA-binding transcription factor activity
H3G96_RS14895	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H3G96_RS14900	COG1285	pathogenesis
H3G96_RS14905	COG2814	Major facilitator Superfamily
H3G96_RS14910	COG1447	Phosphotransferase system cellobiose-specific component IIA
H3G96_RS14915	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS14940	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS14960	COG0243	molybdopterin cofactor binding
H3G96_RS14965	COG3781	membrane
H3G96_RS14990	COG1764	response to oxidative stress
H3G96_RS15000	COG3111	PFAM Bacterial OB fold (BOF) protein
H3G96_RS15010	COG2323	membrane
H3G96_RS15020	COG0366	Alpha amylase catalytic
H3G96_RS15030	COG3685	Protein conserved in bacteria
H3G96_RS15040	COG3729	General stress protein
H3G96_RS15045	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS15090	COG0488	(ABC) transporter
H3G96_RS15105	COG1064	alcohol dehydrogenase
H3G96_RS15110	COG0747	negative chemotaxis
H3G96_RS15120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H3G96_RS15130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H3G96_RS15140	COG2814	Major facilitator Superfamily
H3G96_RS15150	COG2326	polyphosphate kinase activity
H3G96_RS15165	COG2864	formate dehydrogenase
H3G96_RS15170	COG0437	4 iron, 4 sulfur cluster binding
H3G96_RS15195	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H3G96_RS15210	COG3485	protocatechuate 3,4-dioxygenase
H3G96_RS15215	COG4829	muconolactone delta-isomerase
H3G96_RS15220	COG4948	Mandelate Racemase Muconate Lactonizing
H3G96_RS15225	COG1414	Transcriptional regulator
H3G96_RS15245	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H3G96_RS15250	COG1140	nitrate reductase beta subunit
H3G96_RS15255	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H3G96_RS15260	COG2181	nitrate reductase activity
H3G96_RS15265	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H3G96_RS15270	COG1178	ABC-type Fe3 transport system permease component
H3G96_RS15275	COG1840	ABC-type Fe3 transport system, periplasmic component
H3G96_RS15280	COG3842	ATPase activity
H3G96_RS15285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H3G96_RS15320	COG0625	glutathione transferase activity
H3G96_RS15330	COG1126	abc transporter atp-binding protein
H3G96_RS15335	COG0765	amino acid transport
H3G96_RS15345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3G96_RS15350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H3G96_RS15355	COG1473	amidohydrolase
H3G96_RS15360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H3G96_RS15365	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H3G96_RS15390	COG4772	TonB-dependent receptor
H3G96_RS15395	COG1228	amidohydrolase
H3G96_RS15400	COG3691	Protein conserved in bacteria
H3G96_RS15415	COG2130	NADP-dependent
H3G96_RS15425	COG1247	-acetyltransferase
H3G96_RS15430	COG3238	Protein conserved in bacteria
H3G96_RS15440	COG0747	negative chemotaxis
H3G96_RS15445	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS15480	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS15485	COG1177	transmembrane transport
H3G96_RS15490	COG1176	ABC-type spermidine putrescine transport system, permease component I
H3G96_RS15495	COG3842	ATPase activity
H3G96_RS15500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H3G96_RS15505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H3G96_RS15510	COG1271	oxidase subunit
H3G96_RS15515	COG1294	oxidase, subunit
H3G96_RS15535	COG0826	peptidase U32
H3G96_RS15545	COG1396	sequence-specific DNA binding
H3G96_RS15550	COG3135	benzoate transporter
H3G96_RS15555	COG3708	Transcriptional regulator
H3G96_RS15555	COG2207	Transcriptional regulator
H3G96_RS15570	COG0500	methyltransferase
H3G96_RS15575	COG1275	C4-dicarboxylate transporter malic acid transport protein
H3G96_RS15580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H3G96_RS15585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H3G96_RS15600	COG2272	Belongs to the type-B carboxylesterase lipase family
H3G96_RS15605	COG5383	Protein conserved in bacteria
H3G96_RS15610	COG3485	protocatechuate 3,4-dioxygenase
H3G96_RS15615	COG3485	protocatechuate 3,4-dioxygenase
H3G96_RS15620	COG0583	DNA-binding transcription factor activity
H3G96_RS15640	COG3038	cytochrome b561
H3G96_RS15660	COG2814	Major facilitator Superfamily
H3G96_RS15670	COG0673	inositol 2-dehydrogenase activity
H3G96_RS15680	COG2723	6-phospho-beta-galactosidase activity
H3G96_RS15715	COG4659	FMN binding
H3G96_RS15725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H3G96_RS15735	COG0625	glutathione transferase activity
H3G96_RS15740	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H3G96_RS15755	COG3895	Periplasmic Protein
H3G96_RS15770	COG3706	GGDEF domain
H3G96_RS15785	COG1566	PFAM secretion protein HlyD family protein
H3G96_RS15790	COG1289	transmembrane transporter activity
H3G96_RS15795	COG2032	superoxide dismutase activity
H3G96_RS15800	COG4989	oxidoreductase activity
H3G96_RS15805	COG3313	Fe-S protein
H3G96_RS15810	COG1309	transcriptional regulator
H3G96_RS15815	COG1902	pentaerythritol trinitrate reductase activity
H3G96_RS15820	COG0346	lactoylglutathione lyase activity
H3G96_RS15830	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H3G96_RS15835	COG0791	NLP P60 protein
H3G96_RS15850	COG2814	Major facilitator Superfamily
H3G96_RS15865	COG0583	DNA-binding transcription factor activity
H3G96_RS15870	COG2814	Major facilitator Superfamily
H3G96_RS15875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H3G96_RS15880	COG0307	riboflavin synthase, alpha
H3G96_RS15935	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H3G96_RS15970	COG1349	DNA-binding transcription factor activity
H3G96_RS15975	COG0346	lactoylglutathione lyase activity
H3G96_RS16000	COG0444	Belongs to the ABC transporter superfamily
H3G96_RS16005	COG4608	Belongs to the ABC transporter superfamily
H3G96_RS16035	COG3321	synthase
H3G96_RS16035	COG0604	alcohol dehydrogenase
H3G96_RS16035	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS16080	COG0402	S-adenosylhomocysteine deaminase activity
H3G96_RS16105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H3G96_RS16110	COG0277	FAD linked oxidase domain protein
H3G96_RS16135	COG0583	DNA-binding transcription factor activity
H3G96_RS16145	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H3G96_RS16155	COG1250	3-hydroxyacyl-CoA dehydrogenase
H3G96_RS16160	COG2610	gluconate transmembrane transporter activity
H3G96_RS16165	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS16200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H3G96_RS16235	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
H3G96_RS16255	COG4235	cytochrome complex assembly
H3G96_RS16255	COG3088	subunit of a heme lyase
H3G96_RS16260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H3G96_RS16265	COG1138	Cytochrome C-type biogenesis protein
H3G96_RS16280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H3G96_RS16285	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H3G96_RS16290	COG4133	protoheme IX ABC transporter activity
H3G96_RS16320	COG1175	transmembrane transport
H3G96_RS16330	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H3G96_RS16335	COG3383	formate dehydrogenase (NAD+) activity
H3G96_RS16375	COG1126	abc transporter atp-binding protein
H3G96_RS16380	COG0765	amino acid transport
H3G96_RS16400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3G96_RS16405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3G96_RS16410	COG1120	ATPase activity
H3G96_RS16415	COG4774	siderophore transport
H3G96_RS16420	COG1116	anion transmembrane transporter activity
H3G96_RS16425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H3G96_RS16445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H3G96_RS16450	COG0583	DNA-binding transcription factor activity
H3G96_RS16470	COG2814	Major facilitator Superfamily
H3G96_RS16505	COG1414	Transcriptional regulator
H3G96_RS16510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H3G96_RS16515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3G96_RS16520	COG1120	ATPase activity
H3G96_RS16530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H3G96_RS16535	COG2271	Major facilitator Superfamily
H3G96_RS16540	COG1082	Xylose isomerase domain protein TIM barrel
H3G96_RS16540	COG3185	4-Hydroxyphenylpyruvate dioxygenase
H3G96_RS16545	COG1309	transcriptional regulator
H3G96_RS16575	COG1376	ErfK ybiS ycfS ynhG family protein
H3G96_RS16590	COG0719	Fe-S assembly protein
H3G96_RS16595	COG0396	ATPase activity
H3G96_RS16600	COG0719	Fe-S assembly protein
H3G96_RS16605	COG0316	Belongs to the HesB IscA family
H3G96_RS16625	COG1309	transcriptional regulator
H3G96_RS16630	COG1304	FMN binding
H3G96_RS16655	COG0583	DNA-binding transcription factor activity
H3G96_RS16665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3G96_RS16670	COG1120	ATPase activity
H3G96_RS16695	COG2261	transglycosylase associated protein
H3G96_RS16700	COG2050	protein possibly involved in aromatic compounds catabolism
H3G96_RS16705	COG0277	FAD linked oxidase domain protein
H3G96_RS16705	COG0247	lactate metabolic process
H3G96_RS16710	COG0628	permease
H3G96_RS16720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H3G96_RS16720	COG0574	Belongs to the PEP-utilizing enzyme family
H3G96_RS16735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H3G96_RS16740	COG4256	Hemin uptake protein
H3G96_RS16750	COG0791	NLP P60 protein
H3G96_RS16760	COG0386	Belongs to the glutathione peroxidase family
H3G96_RS16780	COG0583	DNA-binding transcription factor activity
H3G96_RS16800	COG0072	phenylalanine-tRNA ligase activity
H3G96_RS16800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H3G96_RS16840	COG3137	Salt-induced outer membrane protein
H3G96_RS16845	COG1105	Belongs to the carbohydrate kinase PfkB family
H3G96_RS16855	COG3001	Fructosamine kinase
H3G96_RS16865	COG2350	Protein conserved in bacteria
H3G96_RS16875	COG2353	YceI-like domain
H3G96_RS16895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H3G96_RS16905	COG0444	Belongs to the ABC transporter superfamily
H3G96_RS16910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H3G96_RS16915	COG0601	transmembrane transport
H3G96_RS16920	COG4166	transmembrane transport
H3G96_RS16925	COG2095	MarC family integral membrane protein
H3G96_RS16935	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS16935	COG1454	alcohol dehydrogenase
H3G96_RS16940	COG1435	thymidine kinase activity
H3G96_RS16950	COG2916	Histone family protein nucleoid-structuring protein H-NS
H3G96_RS16955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H3G96_RS16960	COG0745	RESPONSE REGULATOR receiver
H3G96_RS16965	COG1752	Esterase of the alpha-beta hydrolase superfamily
H3G96_RS16975	COG0788	formyltetrahydrofolate deformylase activity
H3G96_RS17010	COG1522	sequence-specific DNA binding
H3G96_RS17020	COG2181	nitrate reductase activity
H3G96_RS17025	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H3G96_RS17030	COG1140	nitrate reductase beta subunit
H3G96_RS17035	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H3G96_RS17045	COG2223	nitrite transmembrane transporter activity
H3G96_RS17050	COG3850	Histidine kinase
H3G96_RS17055	COG2197	response regulator
H3G96_RS17060	COG4932	domain protein
H3G96_RS17065	COG0243	molybdopterin cofactor binding
H3G96_RS17070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H3G96_RS17070	COG2146	nitrite reductase [NAD(P)H] activity
H3G96_RS17075	COG1116	anion transmembrane transporter activity
H3G96_RS17085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H3G96_RS17090	COG3707	response regulator
H3G96_RS17095	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H3G96_RS17105	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H3G96_RS17110	COG4572	Cation transport regulator
H3G96_RS17115	COG0387	Pfam Sodium calcium exchanger
H3G96_RS17135	COG2890	protein-(glutamine-N5) methyltransferase activity
H3G96_RS17165	COG0659	secondary active sulfate transmembrane transporter activity
H3G96_RS17185	COG0012	GTP binding
H3G96_RS17345	COG2885	chlorophyll binding
H3G96_RS17365	COG3122	Protein conserved in bacteria
H3G96_RS17380	COG0583	DNA-binding transcription factor activity
H3G96_RS17410	COG0583	DNA-binding transcription factor activity
H3G96_RS17445	COG1882	Formate acetyltransferase
H3G96_RS17460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H3G96_RS17465	COG0583	DNA-binding transcription factor activity
H3G96_RS17505	COG2308	Evidence 4 Homologs of previously reported genes of
H3G96_RS17520	COG4774	siderophore transport
H3G96_RS17530	COG1619	proteins homologs of microcin C7 resistance protein MccF
H3G96_RS17555	COG2719	SpoVR family
H3G96_RS17585	COG0179	Fumarylacetoacetate (FAA) hydrolase
H3G96_RS17600	COG2894	cell division
H3G96_RS17610	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H3G96_RS17620	COG3065	identical protein binding
H3G96_RS17630	COG1199	ATP-dependent helicase activity
H3G96_RS17635	COG0251	oxidation-reduction process
H3G96_RS17655	COG1760	l-serine dehydratase
H3G96_RS17660	COG2200	EAL domain
H3G96_RS17665	COG1253	flavin adenine dinucleotide binding
H3G96_RS17670	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS17670	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H3G96_RS17675	COG3715	PTS system
H3G96_RS17680	COG3716	PTS system mannose fructose sorbose family IID component
H3G96_RS17695	COG2226	methyltransferase
H3G96_RS17700	COG0768	penicillin binding
H3G96_RS17730	COG1414	Transcriptional regulator
H3G96_RS17735	COG2814	Major facilitator Superfamily
H3G96_RS17755	COG1956	GAF domain-containing protein
H3G96_RS17760	COG2995	paraquat-inducible protein a
H3G96_RS17765	COG3008	intermembrane lipid transfer
H3G96_RS17790	COG2990	Protein conserved in bacteria
H3G96_RS17805	COG1276	copper resistance
H3G96_RS17810	COG2372	response to copper ion
H3G96_RS17820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H3G96_RS17825	COG1770	oligopeptidase
H3G96_RS17830	COG2979	Protein of unknown function (DUF533)
H3G96_RS17835	COG3141	response to X-ray
H3G96_RS17845	COG0800	Aldolase
H3G96_RS17850	COG0129	dihydroxy-acid dehydratase activity
H3G96_RS17855	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H3G96_RS17865	COG1737	Transcriptional regulator
H3G96_RS17875	COG1560	Kdo2-lipid A biosynthetic process
H3G96_RS17880	COG0739	heme binding
H3G96_RS17885	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
H3G96_RS17895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H3G96_RS17920	COG0494	nUDIX hydrolase
H3G96_RS17930	COG1335	isochorismatase
H3G96_RS17935	COG1801	Protein of unknown function DUF72
H3G96_RS17940	COG3788	relative of glutathione S-transferase, MAPEG superfamily
H3G96_RS17960	COG3102	Protein conserved in bacteria
H3G96_RS17970	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H3G96_RS17995	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS18005	COG1879	ABC-type sugar transport system periplasmic component
H3G96_RS18015	COG1528	Iron-storage protein
H3G96_RS18025	COG2211	Major facilitator Superfamily
H3G96_RS18035	COG0477	Major facilitator Superfamily
H3G96_RS18050	COG1528	Iron-storage protein
H3G96_RS18060	COG0814	amino acid
H3G96_RS18065	COG3318	Belongs to the UPF0149 family
H3G96_RS18065	COG3012	SEC-C Motif Domain Protein
H3G96_RS18100	COG2197	response regulator
H3G96_RS18110	COG2197	response regulator
H3G96_RS18115	COG1126	abc transporter atp-binding protein
H3G96_RS18120	COG0765	amino acid transport
H3G96_RS18130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3G96_RS18135	COG0366	Alpha amylase catalytic
H3G96_RS18165	COG2354	Protein conserved in bacteria
H3G96_RS18170	COG0697	spore germination
H3G96_RS18175	COG3727	T/G mismatch-specific endonuclease activity
H3G96_RS18180	COG0270	DNA (cytosine-5-)-methyltransferase activity
H3G96_RS18185	COG1418	mRNA catabolic process
H3G96_RS18195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H3G96_RS18240	COG0025	NhaP-type Na H and K H
H3G96_RS18250	COG0604	alcohol dehydrogenase
H3G96_RS18270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H3G96_RS18280	COG0534	Mate efflux family protein
H3G96_RS18290	COG0582	viral genome integration into host DNA
H3G96_RS18295	COG1169	isochorismate synthase
H3G96_RS18300	COG2814	Major facilitator Superfamily
H3G96_RS18305	COG1132	(ABC) transporter
H3G96_RS18320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H3G96_RS18320	COG2226	methyltransferase
H3G96_RS18320	COG3433	isochorismatase activity
H3G96_RS18340	COG1021	2,3-dihydroxybenzoate-AMP ligase
H3G96_RS18345	COG4771	TonB-dependent receptor
H3G96_RS18415	COG3504	Conjugal transfer protein
H3G96_RS18460	COG2003	Belongs to the UPF0758 family
H3G96_RS18510	COG3706	GGDEF domain
H3G96_RS18535	COG3615	Tellurite resistance protein tehB
H3G96_RS18545	COG3300	MHYT domain
H3G96_RS18545	COG5001	Diguanylate cyclase
H3G96_RS18555	COG0477	Major facilitator Superfamily
H3G96_RS18560	COG0095	Lipoate-protein ligase
H3G96_RS18565	COG0583	DNA-binding transcription factor activity
H3G96_RS18570	COG1942	4-Oxalocrotonate Tautomerase
H3G96_RS18580	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H3G96_RS18600	COG1289	transmembrane transporter activity
H3G96_RS18610	COG3344	reverse transcriptase
H3G96_RS18620	COG2925	Exonuclease
H3G96_RS18630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H3G96_RS18635	COG0640	Transcriptional regulator
H3G96_RS18640	COG0531	amino acid
H3G96_RS18650	COG0583	DNA-binding transcription factor activity
H3G96_RS18655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H3G96_RS18685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H3G96_RS18705	COG1215	transferase activity, transferring glycosyl groups
H3G96_RS18710	COG0438	transferase activity, transferring glycosyl groups
H3G96_RS18785	COG1088	dTDP-glucose 4,6-dehydratase activity
H3G96_RS18820	COG0438	transferase activity, transferring glycosyl groups
H3G96_RS18830	COG1215	transferase activity, transferring glycosyl groups
H3G96_RS18885	COG1253	flavin adenine dinucleotide binding
H3G96_RS18890	COG2982	Protein involved in outer membrane biogenesis
H3G96_RS18905	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H3G96_RS18910	COG0443	Heat shock 70 kDa protein
H3G96_RS18915	COG5002	protein histidine kinase activity
H3G96_RS18935	COG1301	dicarboxylic acid transport
H3G96_RS18960	COG2205	protein histidine kinase activity
H3G96_RS18965	COG0745	RESPONSE REGULATOR receiver
H3G96_RS18970	COG0826	peptidase U32
H3G96_RS18980	COG4608	Belongs to the ABC transporter superfamily
H3G96_RS18985	COG0444	Belongs to the ABC transporter superfamily
H3G96_RS18990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H3G96_RS18995	COG0601	transmembrane transport
H3G96_RS19000	COG0747	negative chemotaxis
H3G96_RS19005	COG4948	Mandelate Racemase Muconate Lactonizing
H3G96_RS19010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H3G96_RS19020	COG1070	Carbohydrate kinase
H3G96_RS19045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H3G96_RS19055	COG1830	Aldolase
H3G96_RS19060	COG0351	phosphomethylpyrimidine kinase
H3G96_RS19075	COG0583	DNA-binding transcription factor activity
H3G96_RS19085	COG2252	PERMEase
H3G96_RS19090	COG0583	DNA-binding transcription factor activity
H3G96_RS19095	COG5455	response to cobalt ion
H3G96_RS19115	COG4807	Protein conserved in bacteria
H3G96_RS19125	COG3275	phosphorelay sensor kinase activity
H3G96_RS19135	COG1174	glycine betaine transport
H3G96_RS19140	COG1125	glycine betaine transport
H3G96_RS19145	COG1174	glycine betaine transport
H3G96_RS19150	COG1732	Glycine betaine
H3G96_RS19155	COG1472	Belongs to the glycosyl hydrolase 3 family
H3G96_RS19160	COG0277	FAD linked oxidase domain protein
H3G96_RS19175	COG1686	Belongs to the peptidase S11 family
H3G96_RS19185	COG0586	Pfam SNARE associated Golgi protein
H3G96_RS19190	COG1538	Outer membrane efflux protein
H3G96_RS19195	COG2723	6-phospho-beta-galactosidase activity
H3G96_RS19210	COG3659	wide pore channel activity
H3G96_RS19215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H3G96_RS19225	COG1346	cytolysis
H3G96_RS19235	COG2949	membrane
H3G96_RS19245	COG1129	ABC transporter
H3G96_RS19260	COG2311	Membrane
H3G96_RS19275	COG4771	TonB-dependent receptor
H3G96_RS19285	COG0833	amino acid
H3G96_RS19290	COG0583	DNA-binding transcription factor activity
H3G96_RS19295	COG2855	membrane
H3G96_RS19305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H3G96_RS19305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H3G96_RS19305	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H3G96_RS19310	COG1105	Belongs to the carbohydrate kinase PfkB family
H3G96_RS19315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS19315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS19340	COG1312	Catalyzes the dehydration of D-mannonate
H3G96_RS19345	COG0246	Mannitol dehydrogenase
H3G96_RS19350	COG0523	cobalamin synthesis protein
H3G96_RS19355	COG0671	phosphoesterase, PA-phosphatase related
H3G96_RS19360	COG0791	NLP P60 protein
H3G96_RS19365	COG2200	EAL domain
H3G96_RS19370	COG4166	transmembrane transport
H3G96_RS19375	COG4174	ABC transporter (Permease)
H3G96_RS19380	COG4239	(ABC) transporter, permease
H3G96_RS19385	COG4172	Belongs to the ABC transporter superfamily
H3G96_RS19395	COG2814	Major facilitator Superfamily
H3G96_RS19400	COG1187	pseudouridine synthase activity
H3G96_RS19405	COG1061	Type III restriction enzyme res subunit
H3G96_RS19425	COG0494	nUDIX hydrolase
H3G96_RS19430	COG1349	DNA-binding transcription factor activity
H3G96_RS19455	COG0628	permease
H3G96_RS19470	COG0659	secondary active sulfate transmembrane transporter activity
H3G96_RS19475	COG2239	Acts as a magnesium transporter
H3G96_RS19480	COG4615	Cyclic peptide transporter
H3G96_RS19485	COG3145	DNA-N1-methyladenine dioxygenase activity
H3G96_RS19490	COG2169	Transcriptional regulator
H3G96_RS19490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H3G96_RS19505	COG2198	Histidine kinase
H3G96_RS19505	COG0642	Histidine kinase
H3G96_RS19515	COG2205	protein histidine kinase activity
H3G96_RS19515	COG0784	Response regulator, receiver
H3G96_RS19540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H3G96_RS19545	COG0584	glycerophosphoryl diester phosphodiesterase
H3G96_RS19565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H3G96_RS19575	COG0247	lactate metabolic process
H3G96_RS19585	COG2271	Major facilitator Superfamily
H3G96_RS19595	COG1414	Transcriptional regulator
H3G96_RS19610	COG5464	transposase or invertase
H3G96_RS19620	COG0318	PFAM AMP-dependent synthetase and ligase
H3G96_RS19645	COG1169	isochorismate synthase
H3G96_RS19650	COG2153	protein acetylation
H3G96_RS19665	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H3G96_RS19670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H3G96_RS19680	COG0839	Belongs to the complex I subunit 6 family
H3G96_RS19725	COG0583	DNA-binding transcription factor activity
H3G96_RS19730	COG0436	Aminotransferase
H3G96_RS19740	COG0471	metal ion transport
H3G96_RS19740	COG0490	domain, Protein
H3G96_RS19745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H3G96_RS19765	COG0280	phosphate acetyltransferase
H3G96_RS19765	COG0857	belongs to the CobB CobQ family
H3G96_RS19770	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H3G96_RS19775	COG0622	Phosphoesterase
H3G96_RS19780	COG0625	glutathione transferase activity
H3G96_RS19785	COG0625	glutathione transferase activity
H3G96_RS19790	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H3G96_RS19795	COG1090	epimerase
H3G96_RS19810	COG4598	ABC transporter
H3G96_RS19815	COG4160	amino acid transport
H3G96_RS19840	COG0163	prenyltransferase activity
H3G96_RS19845	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H3G96_RS19850	COG1286	toxin biosynthetic process
H3G96_RS19855	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
H3G96_RS19860	COG0285	dihydrofolate synthase activity
H3G96_RS19870	COG0586	Pfam SNARE associated Golgi protein
H3G96_RS19880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H3G96_RS19900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H3G96_RS19915	COG3101	peptidyl-lysine hydroxylation
H3G96_RS19920	COG0730	response to heat
H3G96_RS19945	COG2062	phosphohistidine phosphatase, SixA
H3G96_RS19960	COG3691	Protein conserved in bacteria
H3G96_RS19970	COG2853	Lipoprotein
H3G96_RS19975	COG2116	formate transmembrane transporter activity
H3G96_RS19995	COG0583	DNA-binding transcription factor activity
H3G96_RS20000	COG0590	tRNA wobble adenosine to inosine editing
H3G96_RS20005	COG2807	transmembrane transport
H3G96_RS20015	COG0436	Aminotransferase
H3G96_RS20030	COG3275	phosphorelay sensor kinase activity
H3G96_RS20035	COG3279	Response regulator of the LytR AlgR family
H3G96_RS20050	COG3961	Belongs to the TPP enzyme family
H3G96_RS20055	COG0667	Aldo Keto reductase
H3G96_RS20070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H3G96_RS20075	COG2200	EAL domain
H3G96_RS20075	COG2199	diguanylate cyclase activity
H3G96_RS20090	COG3415	Transposase
H3G96_RS20095	COG3415	Transposase
H3G96_RS20125	COG0583	DNA-binding transcription factor activity
H3G96_RS20130	COG0385	Bile acid
H3G96_RS20135	COG3530	Putative quorum-sensing-regulated virulence factor
H3G96_RS20155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H3G96_RS20190	COG4319	ketosteroid isomerase
H3G96_RS20200	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H3G96_RS20205	COG4208	sulfate ABC transporter
H3G96_RS20210	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H3G96_RS20215	COG4150	thiosulfate binding
H3G96_RS20225	COG2837	iron assimilation
H3G96_RS20245	COG0860	N-Acetylmuramoyl-L-alanine amidase
H3G96_RS20335	COG4810	utilization protein
H3G96_RS20345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H3G96_RS20350	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H3G96_RS20355	COG5342	invasion associated locus B
H3G96_RS20365	COG0493	'glutamate synthase
H3G96_RS20365	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H3G96_RS20370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H3G96_RS20380	COG1393	Belongs to the ArsC family
H3G96_RS20395	COG0400	carboxylic ester hydrolase activity
H3G96_RS20400	COG1444	tRNA N-acetyltransferase activity
H3G96_RS20405	COG2321	neutral zinc metallopeptidase
H3G96_RS20415	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H3G96_RS20425	COG2716	regulation of RNA biosynthetic process
H3G96_RS20430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H3G96_RS20435	COG0628	permease
H3G96_RS20445	COG4783	chaperone-mediated protein folding
H3G96_RS20450	COG1393	Belongs to the ArsC family
H3G96_RS20465	COG2233	PERMEase
H3G96_RS20475	COG2723	6-phospho-beta-galactosidase activity
H3G96_RS20490	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H3G96_RS20505	COG2200	EAL domain
H3G96_RS20525	COG0641	radical SAM
H3G96_RS20530	COG3119	arylsulfatase activity
H3G96_RS20540	COG3179	chitinase
H3G96_RS20695	COG5484	DNA packaging
H3G96_RS20695	COG3728	DNA packaging
H3G96_RS20705	COG3344	reverse transcriptase
H3G96_RS20790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H3G96_RS20840	COG0517	IMP dehydrogenase activity
H3G96_RS20840	COG0516	GMP reductase activity
H3G96_RS20850	COG1645	bacterial-type flagellum-dependent swarming motility
H3G96_RS20870	COG2976	Protein conserved in bacteria
H3G96_RS20900	COG4953	penicillin-binding protein 1C
H3G96_RS20905	COG2373	Large extracellular alpha-helical protein
H3G96_RS20910	COG2897	thiosulfate sulfurtransferase activity
H3G96_RS20930	COG2975	iron-sulfur cluster assembly
H3G96_RS20935	COG0633	Ferredoxin
H3G96_RS20955	COG0822	iron-sulfur transferase activity
H3G96_RS20985	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
H3G96_RS20990	COG3683	transport system, periplasmic component
H3G96_RS20995	COG3711	transcriptional antiterminator
H3G96_RS21000	COG2814	Major facilitator Superfamily
H3G96_RS21005	COG2017	converts alpha-aldose to the beta-anomer
H3G96_RS21010	COG2814	Major facilitator Superfamily
H3G96_RS21010	COG0477	Major facilitator Superfamily
H3G96_RS21015	COG0457	Tetratricopeptide repeat
H3G96_RS21020	COG1940	carbohydrate kinase activity
H3G96_RS21025	COG2259	Doxx family
H3G96_RS21035	COG1017	nitric oxide dioxygenase activity
H3G96_RS21035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H3G96_RS21040	COG0347	Belongs to the P(II) protein family
H3G96_RS21045	COG2204	response regulator
H3G96_RS21050	COG3170	Tfp pilus assembly protein FimV
H3G96_RS21055	COG2205	protein histidine kinase activity
H3G96_RS21060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H3G96_RS21060	COG0047	phosphoribosylformylglycinamidine synthase activity
H3G96_RS21075	COG0560	Phosphoserine phosphatase
H3G96_RS21080	COG1737	Transcriptional regulator
H3G96_RS21085	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H3G96_RS21095	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H3G96_RS21115	COG0681	Belongs to the peptidase S26 family
H3G96_RS21125	COG3086	response to oxidative stress
H3G96_RS21130	COG3026	antisigma factor binding
H3G96_RS21135	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
H3G96_RS21150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H3G96_RS21160	COG0513	Belongs to the DEAD box helicase family
H3G96_RS21175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H3G96_RS21180	COG3118	belongs to the thioredoxin family
H3G96_RS21185	COG3148	PFAM DTW domain containing protein
H3G96_RS21195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H3G96_RS21200	COG5544	Lipoprotein
H3G96_RS21205	COG0477	Major facilitator Superfamily
H3G96_RS21230	COG0542	response to heat
H3G96_RS21245	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H3G96_RS21250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H3G96_RS21260	COG1605	Chorismate mutase
H3G96_RS21260	COG0077	Prephenate dehydratase
H3G96_RS21270	COG0287	Prephenate dehydrogenase
H3G96_RS21270	COG1605	Chorismate mutase
H3G96_RS21275	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H3G96_RS21285	COG2199	diguanylate cyclase activity
H3G96_RS21290	COG2885	chlorophyll binding
H3G96_RS21325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H3G96_RS21330	COG4137	Cytochrome C assembly protein
H3G96_RS21335	COG4536	flavin adenine dinucleotide binding
H3G96_RS21350	COG0497	DNA recombination
H3G96_RS21365	COG2867	negative regulation of translational initiation
H3G96_RS21530	COG4695	Portal protein
H3G96_RS21565	COG3344	reverse transcriptase
H3G96_RS21580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H3G96_RS21615	COG4974	Belongs to the 'phage' integrase family
H3G96_RS21645	COG3121	Chaperone
H3G96_RS21650	COG3539	Fimbrial protein
H3G96_RS21660	COG3284	Transcriptional regulator
H3G96_RS21665	COG0583	DNA-binding transcription factor activity
H3G96_RS21675	COG0640	Transcriptional regulator
H3G96_RS21680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H3G96_RS21695	COG2916	Histone family protein nucleoid-structuring protein H-NS
H3G96_RS21710	COG4575	ribosome binding
H3G96_RS21715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H3G96_RS21720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H3G96_RS21725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H3G96_RS21735	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H3G96_RS21750	COG4176	ABC-type proline glycine betaine transport system permease component
H3G96_RS21760	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H3G96_RS21770	COG1846	Transcriptional regulator
H3G96_RS21775	COG1566	PFAM secretion protein HlyD family protein
H3G96_RS21780	COG2814	Major facilitator Superfamily
H3G96_RS21785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H3G96_RS21805	COG1238	metal cluster binding
H3G96_RS21810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H3G96_RS21815	COG2823	Periplasmic or secreted lipoprotein
H3G96_RS21845	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H3G96_RS21865	COG1546	Belongs to the CinA family
H3G96_RS21875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H3G96_RS21880	COG1121	(ABC) transporter
H3G96_RS21885	COG2951	lytic endotransglycosylase activity
H3G96_RS21890	COG3730	PTS system glucitol sorbitol-specific
H3G96_RS21895	COG3732	PTS system glucitol sorbitol-specific
H3G96_RS21905	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS21910	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS21915	COG1349	DNA-binding transcription factor activity
H3G96_RS21940	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
H3G96_RS21945	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
H3G96_RS21950	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H3G96_RS21955	COG1609	Transcriptional regulator
H3G96_RS21960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H3G96_RS21960	COG1263	PTS System
H3G96_RS21965	COG2723	6-phospho-beta-galactosidase activity
H3G96_RS21975	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H3G96_RS21985	COG3260	NADH ubiquinone oxidoreductase 20
H3G96_RS21990	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H3G96_RS21995	COG3261	NADH dehydrogenase
H3G96_RS21995	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
H3G96_RS22000	COG0650	Formate hydrogenlyase subunit 4
H3G96_RS22005	COG0651	ATP synthesis coupled electron transport
H3G96_RS22010	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H3G96_RS22025	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H3G96_RS22030	COG0298	carbon dioxide binding
H3G96_RS22035	COG0409	Hydrogenase expression formation protein
H3G96_RS22040	COG0309	Hydrogenase expression formation protein (HypE)
H3G96_RS22050	COG2723	6-phospho-beta-galactosidase activity
H3G96_RS22060	COG4580	involved in the transport of maltose and maltodextrins
H3G96_RS22065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS22070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS22075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS22080	COG1447	Phosphotransferase system cellobiose-specific component IIA
H3G96_RS22085	COG1940	carbohydrate kinase activity
H3G96_RS22090	COG1609	Transcriptional regulator
H3G96_RS22095	COG0803	Belongs to the bacterial solute-binding protein 9 family
H3G96_RS22100	COG1121	(ABC) transporter
H3G96_RS22105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H3G96_RS22110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H3G96_RS22125	COG0679	Auxin Efflux Carrier
H3G96_RS22145	COG3720	iron ion transport
H3G96_RS22150	COG4558	Periplasmic binding protein
H3G96_RS22155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3G96_RS22195	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H3G96_RS22200	COG0163	prenyltransferase activity
H3G96_RS22225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H3G96_RS22230	COG1388	LysM domain
H3G96_RS22230	COG4942	peptidase
H3G96_RS22290	COG2234	aminopeptidase activity
H3G96_RS22310	COG0720	synthase
H3G96_RS22315	COG0602	queuosine metabolic process
H3G96_RS22335	COG3956	TIGRFAM MazG family protein
H3G96_RS22340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H3G96_RS22350	COG3850	Histidine kinase
H3G96_RS22350	COG3437	response regulator, receiver
H3G96_RS22350	COG4999	Histidine kinase
H3G96_RS22350	COG2205	protein histidine kinase activity
H3G96_RS22355	COG1929	Belongs to the glycerate kinase type-1 family
H3G96_RS22360	COG4948	Mandelate Racemase Muconate Lactonizing
H3G96_RS22365	COG4948	Mandelate Racemase Muconate Lactonizing
H3G96_RS22370	COG2271	Major facilitator Superfamily
H3G96_RS22375	COG0716	FMN binding
H3G96_RS22380	COG0564	pseudouridine synthase activity
H3G96_RS22385	COG3098	single-species biofilm formation
H3G96_RS22400	COG1611	Belongs to the LOG family
H3G96_RS22405	COG0814	amino acid
H3G96_RS22410	COG1760	l-serine dehydratase
H3G96_RS22415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H3G96_RS22425	COG0477	Major facilitator Superfamily
H3G96_RS22430	COG1464	Belongs to the NlpA lipoprotein family
H3G96_RS22435	COG2011	ABC-type metal ion transport system permease component
H3G96_RS22440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H3G96_RS22455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H3G96_RS22475	COG1454	alcohol dehydrogenase
H3G96_RS22480	COG0235	Class ii aldolase
H3G96_RS22485	COG0738	Major facilitator superfamily
H3G96_RS22505	COG1349	DNA-binding transcription factor activity
H3G96_RS22515	COG2363	Small membrane protein
H3G96_RS22520	COG0583	DNA-binding transcription factor activity
H3G96_RS22530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H3G96_RS22535	COG2166	iron-sulfur cluster assembly
H3G96_RS22540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H3G96_RS22545	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H3G96_RS22710	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
H3G96_RS22740	COG1012	belongs to the aldehyde dehydrogenase family
H3G96_RS22740	COG1454	alcohol dehydrogenase
H3G96_RS22745	COG4656	Part of a membrane complex involved in electron transport
H3G96_RS22775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H3G96_RS22780	COG0860	N-Acetylmuramoyl-L-alanine amidase
H3G96_RS22785	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H3G96_RS22785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H3G96_RS22795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H3G96_RS22800	COG1074	ATP-dependent DNA helicase activity
H3G96_RS22805	COG1025	Belongs to the peptidase M16 family
H3G96_RS22810	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H3G96_RS22815	COG4967	type IV pilus modification protein PilV
H3G96_RS22825	COG4795	General secretion pathway protein
H3G96_RS22830	COG2165	general secretion pathway protein
H3G96_RS22865	COG0861	Integral membrane protein TerC family
H3G96_RS22875	COG0667	Aldo Keto reductase
H3G96_RS22895	COG1609	Transcriptional regulator
H3G96_RS22905	COG2186	Transcriptional regulator
H3G96_RS22910	COG2723	6-phospho-beta-galactosidase activity
H3G96_RS22915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H3G96_RS22920	COG1609	Transcriptional regulator
H3G96_RS22930	COG0583	DNA-binding transcription factor activity
H3G96_RS22935	COG1794	racemase activity, acting on amino acids and derivatives
H3G96_RS22940	COG1917	Cupin 2, conserved barrel domain protein
H3G96_RS22945	COG1175	transmembrane transport
H3G96_RS22950	COG0395	ABC-type sugar transport system, permease component
H3G96_RS22955	COG3842	ATPase activity
H3G96_RS22990	COG2814	Major facilitator Superfamily
H3G96_RS22995	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS23000	COG0823	Involved in the tonB-independent uptake of proteins
H3G96_RS23010	COG0183	Belongs to the thiolase family
H3G96_RS23025	COG0814	amino acid
H3G96_RS23030	COG0667	Aldo Keto reductase
H3G96_RS23075	COG3039	Transposase
H3G96_RS23085	COG0697	spore germination
H3G96_RS23090	COG1846	Transcriptional regulator
H3G96_RS23095	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
H3G96_RS23100	COG0582	viral genome integration into host DNA
H3G96_RS23105	COG4974	Belongs to the 'phage' integrase family
H3G96_RS23115	COG3539	Fimbrial protein
H3G96_RS23120	COG3121	Chaperone
H3G96_RS23125	COG3188	usher protein
H3G96_RS23130	COG3539	Fimbrial protein
H3G96_RS23135	COG3539	Fimbrial protein
H3G96_RS23140	COG3539	Fimbrial protein
H3G96_RS23150	COG2388	GCN5-related N-acetyl-transferase
H3G96_RS23155	COG3592	Divergent 4Fe-4S mono-cluster
H3G96_RS23170	COG1289	transmembrane transporter activity
H3G96_RS23175	COG1538	Outer membrane efflux protein
H3G96_RS23190	COG1393	Belongs to the ArsC family
H3G96_RS23195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H3G96_RS23230	COG0667	Aldo Keto reductase
H3G96_RS23245	COG2814	Major facilitator Superfamily
H3G96_RS23255	COG4942	peptidase
H3G96_RS23275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H3G96_RS23285	COG4974	Belongs to the 'phage' integrase family
H3G96_RS23290	COG0716	FMN binding
H3G96_RS23300	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H3G96_RS23310	COG1272	protein, Hemolysin III
H3G96_RS23320	COG1737	Transcriptional regulator
H3G96_RS23325	COG2723	6-phospho-beta-galactosidase activity
H3G96_RS23345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H3G96_RS23350	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS23370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H3G96_RS23375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H3G96_RS23380	COG0006	proline dipeptidase activity
H3G96_RS23400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H3G96_RS23405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H3G96_RS23420	COG2968	Membrane
H3G96_RS23430	COG0668	transmembrane transport
H3G96_RS23435	COG0191	fructose-bisphosphate aldolase activity
H3G96_RS23450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H3G96_RS23455	COG0501	Belongs to the peptidase M48B family
H3G96_RS23480	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
H3G96_RS23485	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS23515	COG1414	Transcriptional regulator
H3G96_RS23520	COG1028	Short-chain dehydrogenase reductase Sdr
H3G96_RS23535	COG2146	nitrite reductase [NAD(P)H] activity
H3G96_RS23570	COG2814	Major facilitator Superfamily
H3G96_RS23580	COG2356	endonuclease I
H3G96_RS23585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H3G96_RS23590	COG0189	ligase activity
H3G96_RS23610	COG2805	Type II/IV secretion system protein
H3G96_RS23615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H3G96_RS23620	COG0762	integral membrane protein
H3G96_RS23635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H3G96_RS23645	COG3171	Protein conserved in bacteria
H3G96_RS23655	COG1194	a g-specific adenine glycosylase
H3G96_RS23670	COG2211	Major facilitator Superfamily
H3G96_RS23675	COG1982	Orn Lys Arg decarboxylase major
H3G96_RS23680	COG1811	Na channel or pump
H3G96_RS23690	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H3G96_RS23740	COG3039	Transposase
H3G96_RS23755	COG3423	Transcriptional regulator
H3G96_RS23760	COG1278	Cold shock
H3G96_RS23770	COG3423	Transcriptional regulator
H3G96_RS24030	COG0626	cystathionine gamma-synthase activity
H3G96_RS24035	COG0583	DNA-binding transcription factor activity
H3G96_RS24055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H3G96_RS24060	COG0754	glutathionylspermidine amidase activity
H3G96_RS24075	COG0625	glutathione transferase activity
H3G96_RS24100	COG2211	Major facilitator Superfamily
H3G96_RS24105	COG0848	biopolymer transport protein
H3G96_RS24115	COG0626	cystathionine gamma-synthase activity
H3G96_RS24120	COG0586	Pfam SNARE associated Golgi protein
H3G96_RS24125	COG2207	Transcriptional regulator
H3G96_RS24130	COG1979	alcohol dehydrogenase
H3G96_RS24135	COG0656	L-ascorbic acid biosynthetic process
H3G96_RS24145	COG1032	radical SAM domain protein
H3G96_RS24150	COG2132	Multicopper oxidase
H3G96_RS24155	COG0204	Acyl-transferase
H3G96_RS24160	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H3G96_RS24165	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H3G96_RS24170	COG3111	PFAM Bacterial OB fold (BOF) protein
H3G96_RS24180	COG0642	Histidine kinase
H3G96_RS24185	COG2249	NAD(P)H dehydrogenase (quinone) activity
H3G96_RS24190	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H3G96_RS24200	COG3150	esterase
H3G96_RS24205	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H3G96_RS24210	COG3151	Protein conserved in bacteria
H3G96_RS24215	COG0494	nUDIX hydrolase
H3G96_RS24230	COG0754	glutathionylspermidine amidase activity
H3G96_RS24235	COG3384	dioxygenase
H3G96_RS24250	COG2960	long-chain fatty acid transporting porin activity
H3G96_RS24275	COG3025	triphosphatase activity
H3G96_RS24280	COG4991	sh3 domain protein
H3G96_RS24295	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H3G96_RS24365	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H3G96_RS24370	COG0358	DNA primase activity
H3G96_RS24375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H3G96_RS24400	COG2197	response regulator
H3G96_RS24405	COG0784	Response regulator, receiver
H3G96_RS24405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3G96_RS24405	COG2198	Histidine kinase
H3G96_RS24405	COG2205	protein histidine kinase activity
H3G96_RS24415	COG3247	response to pH
H3G96_RS24490	COG2376	Dihydroxyacetone kinase
H3G96_RS24495	COG1461	Dihydroxyacetone kinase
H3G96_RS24510	COG2375	cellular response to nickel ion
H3G96_RS24515	COG1695	Transcriptional regulator
H3G96_RS24565	COG1902	pentaerythritol trinitrate reductase activity
H3G96_RS24565	COG0446	pyridine nucleotide-disulphide oxidoreductase
H3G96_RS24585	COG1451	nucleotide metabolic process
H3G96_RS24590	COG0673	inositol 2-dehydrogenase activity
H3G96_RS24595	COG0861	Integral membrane protein TerC family
H3G96_RS24610	COG2721	sulfolactate sulfo-lyase activity
H3G96_RS24620	COG2271	Major facilitator Superfamily
H3G96_RS24625	COG2186	Transcriptional regulator
H3G96_RS24630	COG0586	Pfam SNARE associated Golgi protein
H3G96_RS24640	COG1422	Protein of unknown function (DUF1090)
H3G96_RS24645	COG4575	ribosome binding
H3G96_RS24650	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
H3G96_RS24660	COG2259	Doxx family
H3G96_RS24665	COG0435	Glutathione S-transferase
H3G96_RS24670	COG3152	Membrane
H3G96_RS24675	COG0583	DNA-binding transcription factor activity
H3G96_RS24680	COG1741	Belongs to the pirin family
H3G96_RS24705	COG1929	Belongs to the glycerate kinase type-1 family
H3G96_RS24710	COG2084	Dehydrogenase
H3G96_RS24720	COG2271	Major facilitator Superfamily
H3G96_RS24725	COG2721	sulfolactate sulfo-lyase activity
H3G96_RS24730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H3G96_RS24735	COG1349	DNA-binding transcription factor activity
H3G96_RS24745	COG1105	Belongs to the carbohydrate kinase PfkB family
H3G96_RS24750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS24750	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H3G96_RS24750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H3G96_RS24755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS24755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS24765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS24770	COG3414	Phosphotransferase system galactitol-specific IIB component
H3G96_RS24775	COG3775	system Galactitol-specific IIC component
H3G96_RS24780	COG1063	alcohol dehydrogenase
H3G96_RS24795	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H3G96_RS24815	COG2823	Periplasmic or secreted lipoprotein
H3G96_RS24820	COG0701	Predicted permease
H3G96_RS24825	COG0702	epimerase
H3G96_RS24830	COG0693	protein deglycase activity
H3G96_RS24845	COG3153	acetyltransferase
H3G96_RS24850	COG3154	lipid carrier protein
H3G96_RS24855	COG0826	peptidase U32
H3G96_RS24860	COG0826	peptidase U32
H3G96_RS24865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H3G96_RS24870	COG0814	amino acid
H3G96_RS24915	COG0195	Participates in both transcription termination and antitermination
H3G96_RS24955	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H3G96_RS24965	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H3G96_RS24970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H3G96_RS24980	COG1534	Rna-binding protein
H3G96_RS24990	COG2027	D-alanyl-D-alanine carboxypeptidase
H3G96_RS25000	COG0697	spore germination
H3G96_RS25015	COG0142	geranyltranstransferase activity
H3G96_RS25020	COG3423	Transcriptional regulator
H3G96_RS25030	COG5007	Belongs to the BolA IbaG family
H3G96_RS25035	COG3113	response to antibiotic
H3G96_RS25040	COG2854	intermembrane phospholipid transfer
H3G96_RS25045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H3G96_RS25050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H3G96_RS25055	COG1127	ABC transporter
H3G96_RS25060	COG0530	calcium, potassium:sodium antiporter activity
H3G96_RS25070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H3G96_RS25075	COG3117	lipopolysaccharide transmembrane transporter activity
H3G96_RS25080	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H3G96_RS25085	COG1137	ATPase activity
H3G96_RS25090	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H3G96_RS25095	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H3G96_RS25100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS25110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H3G96_RS25115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H3G96_RS25120	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H3G96_RS25125	COG2198	Histidine kinase
H3G96_RS25125	COG5002	protein histidine kinase activity
H3G96_RS25125	COG0784	Response regulator, receiver
H3G96_RS25130	COG1312	Catalyzes the dehydration of D-mannonate
H3G96_RS25135	COG1063	alcohol dehydrogenase
H3G96_RS25140	COG2271	Major facilitator Superfamily
H3G96_RS25145	COG1242	4 iron, 4 sulfur cluster binding
H3G96_RS25150	COG0070	glutamate synthase
H3G96_RS25150	COG0069	glutamate synthase activity
H3G96_RS25150	COG0067	glutamate synthase
H3G96_RS25155	COG0493	'glutamate synthase
H3G96_RS25165	COG2969	positive regulation of protein catabolic process
H3G96_RS25170	COG0625	glutathione transferase activity
H3G96_RS25190	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H3G96_RS25195	COG3105	Protein conserved in bacteria
H3G96_RS25200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H3G96_RS25205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H3G96_RS25230	COG2732	(Barnase) inhibitor
H3G96_RS25235	COG1289	transmembrane transporter activity
H3G96_RS25250	COG0583	DNA-binding transcription factor activity
H3G96_RS25255	COG0312	modulator of DNA gyrase
H3G96_RS25260	COG3164	Protein of unknown function
H3G96_RS25265	COG1530	ribonuclease E activity
H3G96_RS25275	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H3G96_RS25280	COG1792	Involved in formation and maintenance of cell shape
H3G96_RS25285	COG1077	Cell shape determining protein MreB Mrl
H3G96_RS25290	COG2200	EAL domain
H3G96_RS25290	COG2199	diguanylate cyclase activity
H3G96_RS25315	COG0511	ligase activity, forming carbon-carbon bonds
H3G96_RS25320	COG0439	Biotin carboxylase
H3G96_RS25325	COG3924	membrane
H3G96_RS25330	COG4145	pantothenate transmembrane transporter activity
H3G96_RS25355	COG1802	Transcriptional regulator
H3G96_RS25355	COG4626	Terminase
H3G96_RS25440	COG3561	AntA/AntB antirepressor
H3G96_RS25455	COG0582	viral genome integration into host DNA
H3G96_RS25460	COG1309	transcriptional regulator
H3G96_RS25465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H3G96_RS25470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H3G96_RS25515	COG0151	Belongs to the GarS family
H3G96_RS25525	COG4191	Histidine kinase
H3G96_RS25530	COG3678	ATP-independent chaperone mediated protein folding
H3G96_RS25565	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
H3G96_RS25580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H3G96_RS25585	COG2104	thiamine diphosphate biosynthetic process
H3G96_RS25600	COG3706	GGDEF domain
H3G96_RS25610	COG1447	Phosphotransferase system cellobiose-specific component IIA
H3G96_RS25615	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H3G96_RS25650	COG0250	Participates in transcription elongation, termination and antitermination
H3G96_RS25695	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H3G96_RS25725	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
H3G96_RS25735	COG1739	Uncharacterized protein family UPF0029
H3G96_RS25775	COG0805	protein transport
H3G96_RS25795	COG3165	ubiquinone biosynthetic process from chorismate
H3G96_RS25825	COG0583	DNA-binding transcription factor activity
H3G96_RS25830	COG0697	spore germination
H3G96_RS25835	COG0561	phosphatase activity
H3G96_RS25840	COG2267	carboxylic ester hydrolase activity
H3G96_RS25845	COG1280	lysine exporter protein (LysE YggA)
H3G96_RS25855	COG1280	lysine exporter protein (LysE YggA)
H3G96_RS25885	COG0210	DNA helicase
H3G96_RS25890	COG1011	Hydrolase
H3G96_RS25920	COG3072	Adenylate cyclase
H3G96_RS25935	COG2959	enzyme of heme biosynthesis
H3G96_RS25940	COG3071	HemY protein
H3G96_RS25985	COG2244	polysaccharide biosynthetic process
H3G96_RS25990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H3G96_RS25995	COG0456	acetyltransferase
H3G96_RS26000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H3G96_RS26005	COG1088	dTDP-glucose 4,6-dehydratase activity
H3G96_RS26010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H3G96_RS26015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H3G96_RS26025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H3G96_RS26030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H3G96_RS26035	COG3118	belongs to the thioredoxin family
H3G96_RS26060	COG1811	Na channel or pump
H3G96_RS26070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H3G96_RS26075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H3G96_RS26085	COG0583	DNA-binding transcription factor activity
H3G96_RS26090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H3G96_RS26105	COG3978	acetolactate synthase activity
H3G96_RS26125	COG3085	chromosome segregation
H3G96_RS26200	COG0583	DNA-binding transcription factor activity
H3G96_RS26215	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H3G96_RS26230	COG3443	Belongs to the bacterial solute-binding protein 9 family
H3G96_RS26235	COG2207	Transcriptional regulator
H3G96_RS26245	COG0371	Dehydrogenase
H3G96_RS26250	COG0697	spore germination
H3G96_RS26260	COG0583	DNA-binding transcription factor activity
H3G96_RS26270	COG0737	Belongs to the 5'-nucleotidase family
H3G96_RS26280	COG0527	aspartate kinase activity
H3G96_RS26280	COG0460	homoserine dehydrogenase
H3G96_RS26285	COG0626	cystathionine gamma-synthase activity
H3G96_RS26300	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H3G96_RS26305	COG1609	Transcriptional regulator
H3G96_RS26310	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H3G96_RS26325	COG1575	Belongs to the MenA family. Type 1 subfamily
H3G96_RS26345	COG3678	ATP-independent chaperone mediated protein folding
H3G96_RS26350	COG0745	RESPONSE REGULATOR receiver
H3G96_RS26355	COG2205	protein histidine kinase activity
H3G96_RS26360	COG2258	MOSC domain
H3G96_RS26365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H3G96_RS26405	COG1129	ABC transporter
H3G96_RS26410	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS26415	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS26420	COG1454	alcohol dehydrogenase
H3G96_RS26430	COG2211	Major facilitator Superfamily
H3G96_RS26490	COG0205	6-phosphofructokinase activity
H3G96_RS26510	COG0437	4 iron, 4 sulfur cluster binding
H3G96_RS26515	COG2864	formate dehydrogenase
H3G96_RS26530	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H3G96_RS26535	COG0657	acetylesterase activity
H3G96_RS26540	COG0456	acetyltransferase
H3G96_RS26555	COG1011	Hydrolase
H3G96_RS26570	COG3852	Histidine kinase
H3G96_RS26585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H3G96_RS26605	COG0204	Acyl-transferase
H3G96_RS26615	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H3G96_RS26620	COG3084	Protein conserved in bacteria
H3G96_RS26630	COG1763	Mo-molybdopterin cofactor biosynthetic process
H3G96_RS26655	COG2186	Transcriptional regulator
H3G96_RS26660	COG0477	Major facilitator Superfamily
H3G96_RS26665	COG1609	Transcriptional regulator
H3G96_RS26670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H3G96_RS26680	COG1172	Belongs to the binding-protein-dependent transport system permease family
H3G96_RS26685	COG1129	ABC transporter
H3G96_RS26715	COG1522	sequence-specific DNA binding
H3G96_RS26720	COG0716	FMN binding
H3G96_RS26735	COG3312	ion transport
H3G96_RS26785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H3G96_RS26790	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H3G96_RS26795	COG0573	inorganic phosphate transmembrane transporter activity
H3G96_RS26800	COG0581	inorganic phosphate transmembrane transporter activity
H3G96_RS26805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H3G96_RS26810	COG0704	Plays a role in the regulation of phosphate uptake
H3G96_RS26820	COG2382	esterase
H3G96_RS26825	COG0363	glucosamine-6-phosphate deaminase activity
H3G96_RS26830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H3G96_RS26835	COG2252	PERMEase
H3G96_RS26840	COG0431	NADPH-dependent FMN reductase
H3G96_RS26845	COG2091	lysine biosynthetic process via aminoadipic acid
H3G96_RS26875	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H3G96_RS26900	COG2203	Gaf domain
H3G96_RS26900	COG2199	diguanylate cyclase activity
H3G96_RS26905	COG5001	Diguanylate cyclase
H3G96_RS26905	COG1716	ATPase activity
H3G96_RS26920	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H3G96_RS26930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H3G96_RS26975	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H3G96_RS27005	COG0739	heme binding
H3G96_RS27015	COG2132	Multicopper oxidase
H3G96_RS27020	COG3667	copper resistance
H3G96_RS27025	COG2372	response to copper ion
H3G96_RS27030	COG1276	copper resistance
H3G96_RS27035	COG0745	RESPONSE REGULATOR receiver
H3G96_RS27040	COG2205	protein histidine kinase activity
H3G96_RS27060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H3G96_RS27075	COG0431	NADPH-dependent FMN reductase
H3G96_RS27105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H3G96_RS27170	COG2801	Transposase and inactivated derivatives
H3G96_RS27185	COG0501	Belongs to the peptidase M48B family
H3G96_RS27200	COG0542	response to heat
H3G96_RS27205	COG0071	Belongs to the small heat shock protein (HSP20) family
H3G96_RS27235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H3G96_RS27260	COG0683	leucine binding
H3G96_RS27265	COG0784	Response regulator, receiver
H3G96_RS27265	COG5002	protein histidine kinase activity
H3G96_RS27265	COG2198	Histidine kinase
H3G96_RS27270	COG0745	RESPONSE REGULATOR receiver
H3G96_RS27410	COG1660	Displays ATPase and GTPase activities
H3G96_RS27465	COG0697	spore germination
H3G96_RS27485	COG4644	lycopene metabolic process
H3G96_RS27865	COG3344	reverse transcriptase
H3G96_RS28130	COG3344	reverse transcriptase
H3G96_RS28395	COG3039	Transposase
H3G96_RS28450	COG2135	peptidase activity
H3G96_RS28660	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H3G96_RS28740	COG3344	reverse transcriptase
H3G96_RS28875	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
H3G96_RS28910	COG3064	Membrane