locus-tag	class	description
H7R40_RS00020	COG0187	DNA topoisomerase II activity
H7R40_RS00025	COG0561	phosphatase activity
H7R40_RS00040	COG2186	Transcriptional regulator
H7R40_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
H7R40_RS00050	COG0800	Aldolase
H7R40_RS00060	COG2271	Major facilitator Superfamily
H7R40_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
H7R40_RS00070	COG5645	(Lipo)protein
H7R40_RS00085	COG3645	SOS response
H7R40_RS00095	COG2188	Transcriptional regulator
H7R40_RS00110	COG2149	membrane
H7R40_RS00130	COG2610	gluconate transmembrane transporter activity
H7R40_RS00140	COG0583	DNA-binding transcription factor activity
H7R40_RS00145	COG2814	Major facilitator Superfamily
H7R40_RS00175	COG0028	Belongs to the TPP enzyme family
H7R40_RS00180	COG0440	acetolactate synthase activity
H7R40_RS00185	COG2197	response regulator
H7R40_RS00195	COG2271	Major facilitator Superfamily
H7R40_RS00235	COG2188	Transcriptional regulator
H7R40_RS00260	COG4580	involved in the transport of maltose and maltodextrins
H7R40_RS00265	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7R40_RS00270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R40_RS00270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R40_RS00280	COG1609	Transcriptional regulator
H7R40_RS00290	COG3384	dioxygenase
H7R40_RS00295	COG0583	DNA-binding transcription factor activity
H7R40_RS00300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7R40_RS00305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7R40_RS00310	COG2828	Protein conserved in bacteria
H7R40_RS00325	COG0697	spore germination
H7R40_RS00330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R40_RS00330	COG1263	PTS System
H7R40_RS00340	COG2814	Major facilitator Superfamily
H7R40_RS00350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R40_RS00385	COG0583	DNA-binding transcription factor activity
H7R40_RS00410	COG1464	Belongs to the NlpA lipoprotein family
H7R40_RS00425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7R40_RS00435	COG1064	alcohol dehydrogenase
H7R40_RS00505	COG0582	viral genome integration into host DNA
H7R40_RS00515	COG2211	Major facilitator Superfamily
H7R40_RS00520	COG1501	Belongs to the glycosyl hydrolase 31 family
H7R40_RS00550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R40_RS00550	COG1263	PTS System
H7R40_RS00555	COG2982	Protein involved in outer membrane biogenesis
H7R40_RS00560	COG2233	PERMEase
H7R40_RS00565	COG0786	glutamate:sodium symporter activity
H7R40_RS00585	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H7R40_RS00610	COG3152	Membrane
H7R40_RS00620	COG1494	fructose-1,6-bisphosphatase
H7R40_RS00625	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7R40_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7R40_RS00635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7R40_RS00655	COG2860	membrane
H7R40_RS00665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7R40_RS00665	COG2169	Transcriptional regulator
H7R40_RS00670	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H7R40_RS00675	COG1561	YicC-like family, N-terminal region
H7R40_RS00695	COG1131	(ABC) transporter
H7R40_RS00730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7R40_RS00765	COG1519	Transferase
H7R40_RS00770	COG1216	Glycosyl transferase, family 2
H7R40_RS00775	COG0438	transferase activity, transferring glycosyl groups
H7R40_RS00785	COG0859	PFAM glycosyl transferase family 9
H7R40_RS00810	COG0859	PFAM glycosyl transferase family 9
H7R40_RS00825	COG0156	8-amino-7-oxononanoate synthase activity
H7R40_RS00835	COG0463	Glycosyl transferase, family 2
H7R40_RS00840	COG2861	carbohydrate metabolic process
H7R40_RS00845	COG4942	peptidase
H7R40_RS00855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7R40_RS00860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H7R40_RS00880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H7R40_RS00890	COG2186	Transcriptional regulator
H7R40_RS00910	COG3722	fumarate hydratase activity
H7R40_RS00930	COG0625	glutathione transferase activity
H7R40_RS00940	COG3276	selenocysteine insertion sequence binding
H7R40_RS00945	COG0235	Class ii aldolase
H7R40_RS00950	COG3623	hexulose-6-phosphate isomerase
H7R40_RS00955	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H7R40_RS00960	COG1070	Carbohydrate kinase
H7R40_RS00965	COG2271	Major facilitator Superfamily
H7R40_RS00975	COG2731	YhcH YjgK YiaL family protein
H7R40_RS00985	COG1414	Transcriptional regulator
H7R40_RS00990	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R40_RS00995	COG3977	Valine--pyruvate aminotransferase
H7R40_RS01000	COG0366	Alpha amylase catalytic
H7R40_RS01005	COG2992	FlgJ-related protein
H7R40_RS01010	COG2207	Transcriptional regulator
H7R40_RS01010	COG1609	Transcriptional regulator
H7R40_RS01015	COG4214	carbohydrate transport
H7R40_RS01025	COG4213	ABC transporter substrate-binding protein
H7R40_RS01040	COG4682	membrane
H7R40_RS01045	COG4682	membrane
H7R40_RS01050	COG3274	enterobacterial common antigen metabolic process
H7R40_RS01090	COG1278	Cold shock
H7R40_RS01095	COG2944	sequence-specific DNA binding
H7R40_RS01100	COG2814	Major facilitator Superfamily
H7R40_RS01120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R40_RS01130	COG1609	Transcriptional regulator
H7R40_RS01135	COG2885	chlorophyll binding
H7R40_RS01140	COG0243	molybdopterin cofactor binding
H7R40_RS01145	COG0456	acetyltransferase
H7R40_RS01150	COG2818	Glycosylase
H7R40_RS01155	COG5571	outer membrane autotransporter
H7R40_RS01160	COG2223	nitrite transmembrane transporter activity
H7R40_RS01190	COG0747	negative chemotaxis
H7R40_RS01195	COG0601	transmembrane transport
H7R40_RS01200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R40_RS01205	COG0444	Belongs to the ABC transporter superfamily
H7R40_RS01210	COG4608	Belongs to the ABC transporter superfamily
H7R40_RS01225	COG2894	cell division
H7R40_RS01235	COG1215	transferase activity, transferring glycosyl groups
H7R40_RS01240	COG0457	Tetratricopeptide repeat
H7R40_RS01255	COG2194	sulfuric ester hydrolase activity
H7R40_RS01285	COG1215	transferase activity, transferring glycosyl groups
H7R40_RS01290	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H7R40_RS01295	COG3118	belongs to the thioredoxin family
H7R40_RS01295	COG0457	Tetratricopeptide repeat
H7R40_RS01300	COG2200	EAL domain
H7R40_RS01300	COG2199	diguanylate cyclase activity
H7R40_RS01310	COG0612	Peptidase, M16
H7R40_RS01320	COG2982	Protein involved in outer membrane biogenesis
H7R40_RS01325	COG0477	Major facilitator Superfamily
H7R40_RS01330	COG1295	ribonuclease BN
H7R40_RS01335	COG0583	DNA-binding transcription factor activity
H7R40_RS01340	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS01345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7R40_RS01355	COG1454	alcohol dehydrogenase
H7R40_RS01365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7R40_RS01370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H7R40_RS01375	COG0671	phosphoesterase, PA-phosphatase related
H7R40_RS01395	COG0589	response to stress
H7R40_RS01405	COG0306	phosphate transporter
H7R40_RS01410	COG2081	HI0933 family
H7R40_RS01415	COG2239	Acts as a magnesium transporter
H7R40_RS01425	COG1124	(ABC) transporter
H7R40_RS01435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R40_RS01440	COG0601	transmembrane transport
H7R40_RS01445	COG0747	negative chemotaxis
H7R40_RS01455	COG3479	Phenolic acid decarboxylase
H7R40_RS01495	COG0628	permease
H7R40_RS01500	COG0477	Major facilitator Superfamily
H7R40_RS01510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H7R40_RS01525	COG3714	YhhN family
H7R40_RS01535	COG3776	membrane
H7R40_RS01540	COG0742	ribosomal rna small subunit methyltransferase
H7R40_RS01545	COG0552	protein localization to endoplasmic reticulum
H7R40_RS01550	COG2884	Cell division ATP-binding protein ftsE
H7R40_RS01555	COG2177	Part of the ABC transporter FtsEX involved in
H7R40_RS01570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7R40_RS01585	COG0683	leucine binding
H7R40_RS01595	COG0683	leucine binding
H7R40_RS01600	COG0559	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS01650	COG0584	glycerophosphoryl diester phosphodiesterase
H7R40_RS01660	COG0405	Gamma-glutamyltransferase
H7R40_RS01665	COG1247	-acetyltransferase
H7R40_RS01675	COG0673	inositol 2-dehydrogenase activity
H7R40_RS01680	COG1741	Belongs to the pirin family
H7R40_RS01685	COG1609	Transcriptional regulator
H7R40_RS01690	COG3265	gluconokinase activity
H7R40_RS01695	COG2610	gluconate transmembrane transporter activity
H7R40_RS01705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H7R40_RS01730	COG0058	SHG alpha-glucan phosphorylase activity
H7R40_RS01745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H7R40_RS01760	COG1349	DNA-binding transcription factor activity
H7R40_RS01770	COG0058	SHG alpha-glucan phosphorylase activity
H7R40_RS01775	COG1640	4-alpha-glucanotransferase
H7R40_RS01780	COG2610	gluconate transmembrane transporter activity
H7R40_RS01790	COG1040	competence protein
H7R40_RS01815	COG1918	ferrous iron import across plasma membrane
H7R40_RS01820	COG2183	response to ionizing radiation
H7R40_RS01825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7R40_RS01850	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H7R40_RS01855	COG1011	Hydrolase
H7R40_RS01865	COG0494	nUDIX hydrolase
H7R40_RS01870	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H7R40_RS01895	COG4796	Type ii and iii secretion system protein
H7R40_RS01910	COG3266	domain, Protein
H7R40_RS01915	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H7R40_RS01920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7R40_RS01945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R40_RS01950	COG0402	S-adenosylhomocysteine deaminase activity
H7R40_RS01955	COG0738	Major facilitator superfamily
H7R40_RS01980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7R40_RS01985	COG1289	transmembrane transporter activity
H7R40_RS01995	COG1765	OsmC-like protein
H7R40_RS02000	COG3954	Phosphoribulokinase
H7R40_RS02010	COG0429	hydrolase of the alpha beta-hydrolase fold
H7R40_RS02015	COG0488	(ABC) transporter
H7R40_RS02030	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H7R40_RS02035	COG1047	Peptidyl-prolyl cis-trans
H7R40_RS02045	COG0545	Peptidyl-prolyl cis-trans isomerase
H7R40_RS02050	COG2964	Protein conserved in bacteria
H7R40_RS02105	COG0051	transcription antitermination factor activity, RNA binding
H7R40_RS02130	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H7R40_RS02145	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H7R40_RS02215	COG0201	protein transport
H7R40_RS02240	COG0202	RNA polymerase activity
H7R40_RS02255	COG0789	Transcriptional regulator
H7R40_RS02260	COG3036	rescue of stalled ribosome
H7R40_RS02290	COG0758	DNA mediated transformation
H7R40_RS02300	COG0551	DNA topoisomerase type I activity
H7R40_RS02320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7R40_RS02355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R40_RS02360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R40_RS02365	COG1309	transcriptional regulator
H7R40_RS02385	COG4145	pantothenate transmembrane transporter activity
H7R40_RS02390	COG3924	membrane
H7R40_RS02395	COG0439	Biotin carboxylase
H7R40_RS02400	COG0511	ligase activity, forming carbon-carbon bonds
H7R40_RS02425	COG2200	EAL domain
H7R40_RS02425	COG2199	diguanylate cyclase activity
H7R40_RS02430	COG1077	Cell shape determining protein MreB Mrl
H7R40_RS02435	COG1792	Involved in formation and maintenance of cell shape
H7R40_RS02440	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H7R40_RS02450	COG1530	ribonuclease E activity
H7R40_RS02455	COG3164	Protein of unknown function
H7R40_RS02460	COG0312	modulator of DNA gyrase
H7R40_RS02465	COG0583	DNA-binding transcription factor activity
H7R40_RS02480	COG1289	transmembrane transporter activity
H7R40_RS02485	COG2732	(Barnase) inhibitor
H7R40_RS02510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7R40_RS02515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7R40_RS02520	COG3105	Protein conserved in bacteria
H7R40_RS02525	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H7R40_RS02545	COG0625	glutathione transferase activity
H7R40_RS02550	COG2969	positive regulation of protein catabolic process
H7R40_RS02560	COG0493	'glutamate synthase
H7R40_RS02565	COG0069	glutamate synthase activity
H7R40_RS02565	COG0067	glutamate synthase
H7R40_RS02565	COG0070	glutamate synthase
H7R40_RS02570	COG1242	4 iron, 4 sulfur cluster binding
H7R40_RS02575	COG2271	Major facilitator Superfamily
H7R40_RS02580	COG1063	alcohol dehydrogenase
H7R40_RS02585	COG1312	Catalyzes the dehydration of D-mannonate
H7R40_RS02590	COG0784	Response regulator, receiver
H7R40_RS02590	COG2198	Histidine kinase
H7R40_RS02590	COG5002	protein histidine kinase activity
H7R40_RS02595	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H7R40_RS02600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7R40_RS02605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R40_RS02615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R40_RS02620	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H7R40_RS02625	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H7R40_RS02630	COG1137	ATPase activity
H7R40_RS02635	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H7R40_RS02640	COG3117	lipopolysaccharide transmembrane transporter activity
H7R40_RS02645	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H7R40_RS02655	COG0530	calcium, potassium:sodium antiporter activity
H7R40_RS02660	COG1127	ABC transporter
H7R40_RS02665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H7R40_RS02670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H7R40_RS02675	COG2854	intermembrane phospholipid transfer
H7R40_RS02680	COG3113	response to antibiotic
H7R40_RS02685	COG5007	Belongs to the BolA IbaG family
H7R40_RS02695	COG3423	Transcriptional regulator
H7R40_RS02700	COG0142	geranyltranstransferase activity
H7R40_RS02715	COG0697	spore germination
H7R40_RS02725	COG2027	D-alanyl-D-alanine carboxypeptidase
H7R40_RS02735	COG1534	Rna-binding protein
H7R40_RS02745	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7R40_RS02750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H7R40_RS02760	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H7R40_RS02800	COG0195	Participates in both transcription termination and antitermination
H7R40_RS02845	COG0814	amino acid
H7R40_RS02850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R40_RS02855	COG0826	peptidase U32
H7R40_RS02860	COG0826	peptidase U32
H7R40_RS02865	COG3154	lipid carrier protein
H7R40_RS02870	COG3153	acetyltransferase
H7R40_RS02885	COG0693	protein deglycase activity
H7R40_RS02890	COG0702	epimerase
H7R40_RS02895	COG0701	Predicted permease
H7R40_RS02900	COG2823	Periplasmic or secreted lipoprotein
H7R40_RS02920	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H7R40_RS02925	COG2721	sulfolactate sulfo-lyase activity
H7R40_RS02930	COG2271	Major facilitator Superfamily
H7R40_RS02940	COG2084	Dehydrogenase
H7R40_RS02945	COG1929	Belongs to the glycerate kinase type-1 family
H7R40_RS02970	COG1741	Belongs to the pirin family
H7R40_RS02975	COG0583	DNA-binding transcription factor activity
H7R40_RS02980	COG3152	Membrane
H7R40_RS02985	COG0435	Glutathione S-transferase
H7R40_RS02990	COG2259	Doxx family
H7R40_RS03000	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
H7R40_RS03005	COG4575	ribosome binding
H7R40_RS03010	COG1422	Protein of unknown function (DUF1090)
H7R40_RS03020	COG0586	Pfam SNARE associated Golgi protein
H7R40_RS03025	COG2186	Transcriptional regulator
H7R40_RS03030	COG2271	Major facilitator Superfamily
H7R40_RS03040	COG2721	sulfolactate sulfo-lyase activity
H7R40_RS03055	COG0861	Integral membrane protein TerC family
H7R40_RS03060	COG0673	inositol 2-dehydrogenase activity
H7R40_RS03065	COG1451	nucleotide metabolic process
H7R40_RS03085	COG1902	pentaerythritol trinitrate reductase activity
H7R40_RS03085	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7R40_RS03135	COG1695	Transcriptional regulator
H7R40_RS03140	COG2375	cellular response to nickel ion
H7R40_RS03155	COG1461	Dihydroxyacetone kinase
H7R40_RS03160	COG2376	Dihydroxyacetone kinase
H7R40_RS03230	COG3247	response to pH
H7R40_RS03240	COG0784	Response regulator, receiver
H7R40_RS03240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R40_RS03240	COG2205	protein histidine kinase activity
H7R40_RS03240	COG2198	Histidine kinase
H7R40_RS03245	COG2197	response regulator
H7R40_RS03270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H7R40_RS03275	COG0358	DNA primase activity
H7R40_RS03280	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H7R40_RS03345	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H7R40_RS03360	COG4991	sh3 domain protein
H7R40_RS03365	COG3025	triphosphatase activity
H7R40_RS03390	COG2960	long-chain fatty acid transporting porin activity
H7R40_RS03405	COG3384	dioxygenase
H7R40_RS03410	COG0754	glutathionylspermidine amidase activity
H7R40_RS03425	COG0494	nUDIX hydrolase
H7R40_RS03430	COG3151	Protein conserved in bacteria
H7R40_RS03435	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7R40_RS03440	COG3150	esterase
H7R40_RS03450	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7R40_RS03455	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7R40_RS03460	COG0642	Histidine kinase
H7R40_RS03470	COG3111	PFAM Bacterial OB fold (BOF) protein
H7R40_RS03475	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H7R40_RS03480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7R40_RS03485	COG0204	Acyl-transferase
H7R40_RS03490	COG2132	Multicopper oxidase
H7R40_RS03495	COG1032	radical SAM domain protein
H7R40_RS03505	COG0656	L-ascorbic acid biosynthetic process
H7R40_RS03510	COG1979	alcohol dehydrogenase
H7R40_RS03515	COG2207	Transcriptional regulator
H7R40_RS03520	COG0586	Pfam SNARE associated Golgi protein
H7R40_RS03525	COG0626	cystathionine gamma-synthase activity
H7R40_RS03535	COG0848	biopolymer transport protein
H7R40_RS03540	COG2211	Major facilitator Superfamily
H7R40_RS03565	COG0625	glutathione transferase activity
H7R40_RS03580	COG0754	glutathionylspermidine amidase activity
H7R40_RS03585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R40_RS03605	COG0583	DNA-binding transcription factor activity
H7R40_RS03610	COG0626	cystathionine gamma-synthase activity
H7R40_RS03645	COG1811	Na channel or pump
H7R40_RS03650	COG1982	Orn Lys Arg decarboxylase major
H7R40_RS03655	COG2211	Major facilitator Superfamily
H7R40_RS03670	COG1194	a g-specific adenine glycosylase
H7R40_RS03680	COG3171	Protein conserved in bacteria
H7R40_RS03695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H7R40_RS03695	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H7R40_RS03700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7R40_RS03705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7R40_RS03720	COG0762	integral membrane protein
H7R40_RS03725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H7R40_RS03730	COG2805	Type II/IV secretion system protein
H7R40_RS03750	COG0189	ligase activity
H7R40_RS03755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7R40_RS03760	COG2356	endonuclease I
H7R40_RS03770	COG2814	Major facilitator Superfamily
H7R40_RS03805	COG2146	nitrite reductase [NAD(P)H] activity
H7R40_RS03820	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS03825	COG1414	Transcriptional regulator
H7R40_RS03855	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS03860	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
H7R40_RS03880	COG0501	Belongs to the peptidase M48B family
H7R40_RS03885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7R40_RS03900	COG0191	fructose-bisphosphate aldolase activity
H7R40_RS03905	COG0668	transmembrane transport
H7R40_RS03915	COG2968	Membrane
H7R40_RS03930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7R40_RS03935	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7R40_RS03955	COG0006	proline dipeptidase activity
H7R40_RS03960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R40_RS03965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R40_RS03985	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS03990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7R40_RS04010	COG2723	6-phospho-beta-galactosidase activity
H7R40_RS04015	COG1737	Transcriptional regulator
H7R40_RS04025	COG1272	protein, Hemolysin III
H7R40_RS04035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H7R40_RS04045	COG0716	FMN binding
H7R40_RS04050	COG4974	Belongs to the 'phage' integrase family
H7R40_RS04060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7R40_RS04080	COG4942	peptidase
H7R40_RS04090	COG2814	Major facilitator Superfamily
H7R40_RS04105	COG0667	Aldo Keto reductase
H7R40_RS04145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H7R40_RS04150	COG1393	Belongs to the ArsC family
H7R40_RS04165	COG1538	Outer membrane efflux protein
H7R40_RS04170	COG1289	transmembrane transporter activity
H7R40_RS04185	COG3592	Divergent 4Fe-4S mono-cluster
H7R40_RS04190	COG2388	GCN5-related N-acetyl-transferase
H7R40_RS04200	COG3539	Fimbrial protein
H7R40_RS04205	COG3539	Fimbrial protein
H7R40_RS04210	COG3539	Fimbrial protein
H7R40_RS04215	COG3188	usher protein
H7R40_RS04220	COG3121	Chaperone
H7R40_RS04225	COG3539	Fimbrial protein
H7R40_RS04235	COG4974	Belongs to the 'phage' integrase family
H7R40_RS04240	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H7R40_RS04260	COG0582	viral genome integration into host DNA
H7R40_RS04265	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
H7R40_RS04270	COG1846	Transcriptional regulator
H7R40_RS04275	COG0697	spore germination
H7R40_RS04325	COG0667	Aldo Keto reductase
H7R40_RS04330	COG0814	amino acid
H7R40_RS04345	COG0183	Belongs to the thiolase family
H7R40_RS04355	COG0823	Involved in the tonB-independent uptake of proteins
H7R40_RS04360	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS04365	COG2814	Major facilitator Superfamily
H7R40_RS04400	COG3842	ATPase activity
H7R40_RS04405	COG0395	ABC-type sugar transport system, permease component
H7R40_RS04410	COG1175	transmembrane transport
H7R40_RS04415	COG1917	Cupin 2, conserved barrel domain protein
H7R40_RS04420	COG1794	racemase activity, acting on amino acids and derivatives
H7R40_RS04425	COG0583	DNA-binding transcription factor activity
H7R40_RS04435	COG1609	Transcriptional regulator
H7R40_RS04440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R40_RS04445	COG2723	6-phospho-beta-galactosidase activity
H7R40_RS04450	COG2186	Transcriptional regulator
H7R40_RS04460	COG1609	Transcriptional regulator
H7R40_RS04480	COG0667	Aldo Keto reductase
H7R40_RS04490	COG0861	Integral membrane protein TerC family
H7R40_RS04525	COG2165	general secretion pathway protein
H7R40_RS04530	COG4795	General secretion pathway protein
H7R40_RS04540	COG4967	type IV pilus modification protein PilV
H7R40_RS04545	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H7R40_RS04550	COG1025	Belongs to the peptidase M16 family
H7R40_RS04555	COG1074	ATP-dependent DNA helicase activity
H7R40_RS04560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7R40_RS04570	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H7R40_RS04570	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H7R40_RS04575	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7R40_RS04580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7R40_RS04610	COG4656	Part of a membrane complex involved in electron transport
H7R40_RS04615	COG1454	alcohol dehydrogenase
H7R40_RS04615	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS04645	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
H7R40_RS04800	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H7R40_RS04805	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H7R40_RS04810	COG2166	iron-sulfur cluster assembly
H7R40_RS04815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7R40_RS04825	COG0583	DNA-binding transcription factor activity
H7R40_RS04830	COG2363	Small membrane protein
H7R40_RS04840	COG1349	DNA-binding transcription factor activity
H7R40_RS04860	COG0738	Major facilitator superfamily
H7R40_RS04865	COG0235	Class ii aldolase
H7R40_RS04870	COG1454	alcohol dehydrogenase
H7R40_RS04890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R40_RS04905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7R40_RS04910	COG2011	ABC-type metal ion transport system permease component
H7R40_RS04915	COG1464	Belongs to the NlpA lipoprotein family
H7R40_RS04920	COG0477	Major facilitator Superfamily
H7R40_RS04930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R40_RS04935	COG1760	l-serine dehydratase
H7R40_RS04940	COG0814	amino acid
H7R40_RS04945	COG1611	Belongs to the LOG family
H7R40_RS04960	COG3098	single-species biofilm formation
H7R40_RS04965	COG0564	pseudouridine synthase activity
H7R40_RS04970	COG0716	FMN binding
H7R40_RS04975	COG2271	Major facilitator Superfamily
H7R40_RS04980	COG4948	Mandelate Racemase Muconate Lactonizing
H7R40_RS04985	COG4948	Mandelate Racemase Muconate Lactonizing
H7R40_RS04990	COG1929	Belongs to the glycerate kinase type-1 family
H7R40_RS04995	COG3437	response regulator, receiver
H7R40_RS04995	COG2205	protein histidine kinase activity
H7R40_RS04995	COG3850	Histidine kinase
H7R40_RS04995	COG4999	Histidine kinase
H7R40_RS05005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7R40_RS05010	COG3956	TIGRFAM MazG family protein
H7R40_RS05030	COG0602	queuosine metabolic process
H7R40_RS05035	COG0720	synthase
H7R40_RS05055	COG2234	aminopeptidase activity
H7R40_RS05115	COG4942	peptidase
H7R40_RS05115	COG1388	LysM domain
H7R40_RS05120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H7R40_RS05145	COG0163	prenyltransferase activity
H7R40_RS05150	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H7R40_RS05175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R40_RS05180	COG4558	Periplasmic binding protein
H7R40_RS05185	COG3720	iron ion transport
H7R40_RS05205	COG0679	Auxin Efflux Carrier
H7R40_RS05220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7R40_RS05225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7R40_RS05230	COG1121	(ABC) transporter
H7R40_RS05240	COG1609	Transcriptional regulator
H7R40_RS05245	COG1940	carbohydrate kinase activity
H7R40_RS05250	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7R40_RS05255	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R40_RS05260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R40_RS05265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R40_RS05280	COG2723	6-phospho-beta-galactosidase activity
H7R40_RS05290	COG0309	Hydrogenase expression formation protein (HypE)
H7R40_RS05295	COG0409	Hydrogenase expression formation protein
H7R40_RS05300	COG0298	carbon dioxide binding
H7R40_RS05305	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H7R40_RS05320	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R40_RS05325	COG0651	ATP synthesis coupled electron transport
H7R40_RS05330	COG0650	Formate hydrogenlyase subunit 4
H7R40_RS05335	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
H7R40_RS05335	COG3261	NADH dehydrogenase
H7R40_RS05340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7R40_RS05345	COG3260	NADH ubiquinone oxidoreductase 20
H7R40_RS05355	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H7R40_RS05365	COG2723	6-phospho-beta-galactosidase activity
H7R40_RS05370	COG1263	PTS System
H7R40_RS05370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R40_RS05375	COG1609	Transcriptional regulator
H7R40_RS05380	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R40_RS05385	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
H7R40_RS05390	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
H7R40_RS05415	COG1349	DNA-binding transcription factor activity
H7R40_RS05420	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R40_RS05425	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS05435	COG3732	PTS system glucitol sorbitol-specific
H7R40_RS05440	COG3730	PTS system glucitol sorbitol-specific
H7R40_RS05445	COG2951	lytic endotransglycosylase activity
H7R40_RS05450	COG1121	(ABC) transporter
H7R40_RS05455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7R40_RS05465	COG1546	Belongs to the CinA family
H7R40_RS05490	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H7R40_RS05520	COG2823	Periplasmic or secreted lipoprotein
H7R40_RS05525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R40_RS05530	COG1238	metal cluster binding
H7R40_RS05550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7R40_RS05555	COG2814	Major facilitator Superfamily
H7R40_RS05560	COG1566	PFAM secretion protein HlyD family protein
H7R40_RS05565	COG1846	Transcriptional regulator
H7R40_RS05575	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H7R40_RS05585	COG4176	ABC-type proline glycine betaine transport system permease component
H7R40_RS05600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7R40_RS05610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H7R40_RS05615	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7R40_RS05620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R40_RS05625	COG4575	ribosome binding
H7R40_RS05640	COG2916	Histone family protein nucleoid-structuring protein H-NS
H7R40_RS05655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7R40_RS05660	COG0640	Transcriptional regulator
H7R40_RS05670	COG0583	DNA-binding transcription factor activity
H7R40_RS05675	COG3284	Transcriptional regulator
H7R40_RS05685	COG3539	Fimbrial protein
H7R40_RS05690	COG3121	Chaperone
H7R40_RS05710	COG3188	usher protein
H7R40_RS05720	COG3539	Fimbrial protein
H7R40_RS05725	COG2197	response regulator
H7R40_RS05740	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS05750	COG0235	Class ii aldolase
H7R40_RS05760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R40_RS05795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R40_RS05800	COG3708	Transcriptional regulator
H7R40_RS05800	COG2207	Transcriptional regulator
H7R40_RS05835	COG0582	viral genome integration into host DNA
H7R40_RS05905	COG0484	heat shock protein binding
H7R40_RS05955	COG1802	Transcriptional regulator
H7R40_RS05955	COG4626	Terminase
H7R40_RS05960	COG4695	Portal protein
H7R40_RS05965	COG0740	serine-type endopeptidase activity
H7R40_RS06035	COG4372	Transposase
H7R40_RS06040	COG3436	PFAM IS66 Orf2 family protein
H7R40_RS06100	COG2867	negative regulation of translational initiation
H7R40_RS06115	COG0497	DNA recombination
H7R40_RS06130	COG4536	flavin adenine dinucleotide binding
H7R40_RS06135	COG4137	Cytochrome C assembly protein
H7R40_RS06140	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7R40_RS06175	COG2885	chlorophyll binding
H7R40_RS06180	COG2199	diguanylate cyclase activity
H7R40_RS06190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7R40_RS06195	COG0287	Prephenate dehydrogenase
H7R40_RS06195	COG1605	Chorismate mutase
H7R40_RS06205	COG1605	Chorismate mutase
H7R40_RS06205	COG0077	Prephenate dehydratase
H7R40_RS06215	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H7R40_RS06220	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7R40_RS06235	COG0542	response to heat
H7R40_RS06260	COG0477	Major facilitator Superfamily
H7R40_RS06265	COG5544	Lipoprotein
H7R40_RS06270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7R40_RS06280	COG3148	PFAM DTW domain containing protein
H7R40_RS06285	COG3118	belongs to the thioredoxin family
H7R40_RS06290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7R40_RS06305	COG0513	Belongs to the DEAD box helicase family
H7R40_RS06315	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H7R40_RS06330	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
H7R40_RS06335	COG3026	antisigma factor binding
H7R40_RS06340	COG3086	response to oxidative stress
H7R40_RS06350	COG0681	Belongs to the peptidase S26 family
H7R40_RS06370	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H7R40_RS06380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R40_RS06385	COG1737	Transcriptional regulator
H7R40_RS06390	COG0560	Phosphoserine phosphatase
H7R40_RS06405	COG0047	phosphoribosylformylglycinamidine synthase activity
H7R40_RS06405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7R40_RS06410	COG2205	protein histidine kinase activity
H7R40_RS06415	COG3170	Tfp pilus assembly protein FimV
H7R40_RS06420	COG2204	response regulator
H7R40_RS06425	COG0347	Belongs to the P(II) protein family
H7R40_RS06430	COG1017	nitric oxide dioxygenase activity
H7R40_RS06430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R40_RS06440	COG2259	Doxx family
H7R40_RS06445	COG1940	carbohydrate kinase activity
H7R40_RS06450	COG0457	Tetratricopeptide repeat
H7R40_RS06455	COG2814	Major facilitator Superfamily
H7R40_RS06455	COG0477	Major facilitator Superfamily
H7R40_RS06460	COG2017	converts alpha-aldose to the beta-anomer
H7R40_RS06465	COG2814	Major facilitator Superfamily
H7R40_RS06470	COG3711	transcriptional antiterminator
H7R40_RS06475	COG3683	transport system, periplasmic component
H7R40_RS06480	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
H7R40_RS06510	COG0822	iron-sulfur transferase activity
H7R40_RS06530	COG0633	Ferredoxin
H7R40_RS06535	COG2975	iron-sulfur cluster assembly
H7R40_RS06555	COG2897	thiosulfate sulfurtransferase activity
H7R40_RS06560	COG2373	Large extracellular alpha-helical protein
H7R40_RS06565	COG4953	penicillin-binding protein 1C
H7R40_RS06595	COG2976	Protein conserved in bacteria
H7R40_RS06625	COG1645	bacterial-type flagellum-dependent swarming motility
H7R40_RS06635	COG0517	IMP dehydrogenase activity
H7R40_RS06635	COG0516	GMP reductase activity
H7R40_RS06645	COG3119	arylsulfatase activity
H7R40_RS06650	COG0641	radical SAM
H7R40_RS06670	COG2200	EAL domain
H7R40_RS06685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7R40_RS06700	COG2723	6-phospho-beta-galactosidase activity
H7R40_RS06710	COG2233	PERMEase
H7R40_RS06725	COG1393	Belongs to the ArsC family
H7R40_RS06730	COG4783	chaperone-mediated protein folding
H7R40_RS06740	COG0628	permease
H7R40_RS06745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7R40_RS06750	COG2716	regulation of RNA biosynthetic process
H7R40_RS06760	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H7R40_RS06770	COG2321	neutral zinc metallopeptidase
H7R40_RS06775	COG1444	tRNA N-acetyltransferase activity
H7R40_RS06780	COG0400	carboxylic ester hydrolase activity
H7R40_RS06795	COG1393	Belongs to the ArsC family
H7R40_RS06805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R40_RS06810	COG0493	'glutamate synthase
H7R40_RS06810	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R40_RS06820	COG5342	invasion associated locus B
H7R40_RS06825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7R40_RS06830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7R40_RS06840	COG4810	utilization protein
H7R40_RS06930	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7R40_RS06950	COG2837	iron assimilation
H7R40_RS06960	COG4150	thiosulfate binding
H7R40_RS06965	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H7R40_RS06970	COG4208	sulfate ABC transporter
H7R40_RS06975	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H7R40_RS06985	COG4319	ketosteroid isomerase
H7R40_RS07020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7R40_RS07040	COG3530	Putative quorum-sensing-regulated virulence factor
H7R40_RS07045	COG0385	Bile acid
H7R40_RS07050	COG0583	DNA-binding transcription factor activity
H7R40_RS07085	COG3415	Transposase
H7R40_RS07090	COG3415	Transposase
H7R40_RS07105	COG2199	diguanylate cyclase activity
H7R40_RS07105	COG2200	EAL domain
H7R40_RS07110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7R40_RS07125	COG0667	Aldo Keto reductase
H7R40_RS07130	COG3961	Belongs to the TPP enzyme family
H7R40_RS07145	COG3279	Response regulator of the LytR AlgR family
H7R40_RS07150	COG3275	phosphorelay sensor kinase activity
H7R40_RS07165	COG0436	Aminotransferase
H7R40_RS07175	COG2807	transmembrane transport
H7R40_RS07180	COG0590	tRNA wobble adenosine to inosine editing
H7R40_RS07185	COG0583	DNA-binding transcription factor activity
H7R40_RS07265	COG0582	viral genome integration into host DNA
H7R40_RS07275	COG2116	formate transmembrane transporter activity
H7R40_RS07280	COG2853	Lipoprotein
H7R40_RS07290	COG3691	Protein conserved in bacteria
H7R40_RS07305	COG2062	phosphohistidine phosphatase, SixA
H7R40_RS07330	COG0730	response to heat
H7R40_RS07335	COG3101	peptidyl-lysine hydroxylation
H7R40_RS07350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7R40_RS07370	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H7R40_RS07380	COG0586	Pfam SNARE associated Golgi protein
H7R40_RS07390	COG0285	dihydrofolate synthase activity
H7R40_RS07395	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
H7R40_RS07400	COG1286	toxin biosynthetic process
H7R40_RS07405	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H7R40_RS07410	COG0163	prenyltransferase activity
H7R40_RS07435	COG4160	amino acid transport
H7R40_RS07440	COG4598	ABC transporter
H7R40_RS07455	COG1090	epimerase
H7R40_RS07460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H7R40_RS07465	COG0625	glutathione transferase activity
H7R40_RS07470	COG0625	glutathione transferase activity
H7R40_RS07475	COG0622	Phosphoesterase
H7R40_RS07480	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H7R40_RS07485	COG0280	phosphate acetyltransferase
H7R40_RS07485	COG0857	belongs to the CobB CobQ family
H7R40_RS07505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R40_RS07510	COG0490	domain, Protein
H7R40_RS07510	COG0471	metal ion transport
H7R40_RS07520	COG0436	Aminotransferase
H7R40_RS07525	COG0583	DNA-binding transcription factor activity
H7R40_RS07570	COG0839	Belongs to the complex I subunit 6 family
H7R40_RS07580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7R40_RS07585	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7R40_RS07600	COG2153	protein acetylation
H7R40_RS07605	COG1169	isochorismate synthase
H7R40_RS07630	COG0318	PFAM AMP-dependent synthetase and ligase
H7R40_RS07640	COG5464	transposase or invertase
H7R40_RS07655	COG1414	Transcriptional regulator
H7R40_RS07665	COG2271	Major facilitator Superfamily
H7R40_RS07675	COG0247	lactate metabolic process
H7R40_RS07685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H7R40_RS07690	COG2271	Major facilitator Superfamily
H7R40_RS07695	COG0584	glycerophosphoryl diester phosphodiesterase
H7R40_RS07700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R40_RS07725	COG2205	protein histidine kinase activity
H7R40_RS07725	COG0784	Response regulator, receiver
H7R40_RS07735	COG0642	Histidine kinase
H7R40_RS07735	COG2198	Histidine kinase
H7R40_RS07755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7R40_RS07755	COG2169	Transcriptional regulator
H7R40_RS07760	COG3145	DNA-N1-methyladenine dioxygenase activity
H7R40_RS07765	COG4615	Cyclic peptide transporter
H7R40_RS07770	COG2239	Acts as a magnesium transporter
H7R40_RS07775	COG0659	secondary active sulfate transmembrane transporter activity
H7R40_RS07790	COG0628	permease
H7R40_RS07855	COG1476	TRANSCRIPTIONal
H7R40_RS07890	COG0582	viral genome integration into host DNA
H7R40_RS07915	COG1349	DNA-binding transcription factor activity
H7R40_RS07920	COG0494	nUDIX hydrolase
H7R40_RS07940	COG1061	Type III restriction enzyme res subunit
H7R40_RS07945	COG1187	pseudouridine synthase activity
H7R40_RS07950	COG2814	Major facilitator Superfamily
H7R40_RS07960	COG4172	Belongs to the ABC transporter superfamily
H7R40_RS07965	COG4239	(ABC) transporter, permease
H7R40_RS07970	COG4174	ABC transporter (Permease)
H7R40_RS07975	COG4166	transmembrane transport
H7R40_RS07980	COG2200	EAL domain
H7R40_RS07985	COG0791	NLP P60 protein
H7R40_RS07990	COG0671	phosphoesterase, PA-phosphatase related
H7R40_RS07995	COG0523	cobalamin synthesis protein
H7R40_RS08000	COG0246	Mannitol dehydrogenase
H7R40_RS08005	COG1312	Catalyzes the dehydration of D-mannonate
H7R40_RS08025	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R40_RS08025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R40_RS08030	COG1105	Belongs to the carbohydrate kinase PfkB family
H7R40_RS08035	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H7R40_RS08035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7R40_RS08035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7R40_RS08045	COG2855	membrane
H7R40_RS08050	COG0583	DNA-binding transcription factor activity
H7R40_RS08055	COG0833	amino acid
H7R40_RS08060	COG4771	TonB-dependent receptor
H7R40_RS08075	COG2311	Membrane
H7R40_RS08090	COG1129	ABC transporter
H7R40_RS08100	COG2949	membrane
H7R40_RS08110	COG1346	cytolysis
H7R40_RS08120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7R40_RS08125	COG3659	wide pore channel activity
H7R40_RS08140	COG2723	6-phospho-beta-galactosidase activity
H7R40_RS08145	COG1538	Outer membrane efflux protein
H7R40_RS08150	COG0586	Pfam SNARE associated Golgi protein
H7R40_RS08160	COG1686	Belongs to the peptidase S11 family
H7R40_RS08170	COG0277	FAD linked oxidase domain protein
H7R40_RS08175	COG1472	Belongs to the glycosyl hydrolase 3 family
H7R40_RS08180	COG1732	Glycine betaine
H7R40_RS08185	COG1174	glycine betaine transport
H7R40_RS08190	COG1125	glycine betaine transport
H7R40_RS08195	COG1174	glycine betaine transport
H7R40_RS08205	COG3275	phosphorelay sensor kinase activity
H7R40_RS08215	COG4807	Protein conserved in bacteria
H7R40_RS08235	COG5455	response to cobalt ion
H7R40_RS08240	COG0583	DNA-binding transcription factor activity
H7R40_RS08245	COG2252	PERMEase
H7R40_RS08255	COG0583	DNA-binding transcription factor activity
H7R40_RS08270	COG0351	phosphomethylpyrimidine kinase
H7R40_RS08275	COG1830	Aldolase
H7R40_RS08310	COG1070	Carbohydrate kinase
H7R40_RS08320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R40_RS08325	COG4948	Mandelate Racemase Muconate Lactonizing
H7R40_RS08330	COG0747	negative chemotaxis
H7R40_RS08335	COG0601	transmembrane transport
H7R40_RS08340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R40_RS08345	COG0444	Belongs to the ABC transporter superfamily
H7R40_RS08350	COG4608	Belongs to the ABC transporter superfamily
H7R40_RS08360	COG0826	peptidase U32
H7R40_RS08365	COG0745	RESPONSE REGULATOR receiver
H7R40_RS08370	COG2205	protein histidine kinase activity
H7R40_RS08395	COG1301	dicarboxylic acid transport
H7R40_RS08415	COG5002	protein histidine kinase activity
H7R40_RS08420	COG0443	Heat shock 70 kDa protein
H7R40_RS08425	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H7R40_RS08440	COG2982	Protein involved in outer membrane biogenesis
H7R40_RS08445	COG1253	flavin adenine dinucleotide binding
H7R40_RS08485	COG5039	Polysaccharide pyruvyl transferase
H7R40_RS08590	COG0438	transferase activity, transferring glycosyl groups
H7R40_RS08595	COG1442	glycosyl transferase family 8
H7R40_RS08595	COG1216	Glycosyl transferase, family 2
H7R40_RS08605	COG0463	Glycosyl transferase, family 2
H7R40_RS08630	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H7R40_RS08660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7R40_RS08665	COG0583	DNA-binding transcription factor activity
H7R40_RS08675	COG0531	amino acid
H7R40_RS08680	COG0640	Transcriptional regulator
H7R40_RS08685	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H7R40_RS08690	COG2925	Exonuclease
H7R40_RS08705	COG1289	transmembrane transporter activity
H7R40_RS08725	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H7R40_RS08735	COG1942	4-Oxalocrotonate Tautomerase
H7R40_RS08740	COG0583	DNA-binding transcription factor activity
H7R40_RS08745	COG0095	Lipoate-protein ligase
H7R40_RS08750	COG0477	Major facilitator Superfamily
H7R40_RS08760	COG5001	Diguanylate cyclase
H7R40_RS08760	COG3300	MHYT domain
H7R40_RS08770	COG3615	Tellurite resistance protein tehB
H7R40_RS08795	COG3706	GGDEF domain
H7R40_RS08815	COG0534	Mate efflux family protein
H7R40_RS08825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7R40_RS08845	COG0604	alcohol dehydrogenase
H7R40_RS08850	COG1309	transcriptional regulator
H7R40_RS08855	COG0025	NhaP-type Na H and K H
H7R40_RS08905	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H7R40_RS08915	COG1418	mRNA catabolic process
H7R40_RS08920	COG0270	DNA (cytosine-5-)-methyltransferase activity
H7R40_RS08925	COG3727	T/G mismatch-specific endonuclease activity
H7R40_RS08930	COG0697	spore germination
H7R40_RS08935	COG2354	Protein conserved in bacteria
H7R40_RS08965	COG0366	Alpha amylase catalytic
H7R40_RS08970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R40_RS08980	COG0765	amino acid transport
H7R40_RS08985	COG1126	abc transporter atp-binding protein
H7R40_RS08990	COG2197	response regulator
H7R40_RS09000	COG2197	response regulator
H7R40_RS09035	COG3318	Belongs to the UPF0149 family
H7R40_RS09035	COG3012	SEC-C Motif Domain Protein
H7R40_RS09040	COG0814	amino acid
H7R40_RS09050	COG1528	Iron-storage protein
H7R40_RS09065	COG0477	Major facilitator Superfamily
H7R40_RS09075	COG2211	Major facilitator Superfamily
H7R40_RS09085	COG1528	Iron-storage protein
H7R40_RS09095	COG1879	ABC-type sugar transport system periplasmic component
H7R40_RS09105	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS09130	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H7R40_RS09140	COG3102	Protein conserved in bacteria
H7R40_RS09160	COG3788	relative of glutathione S-transferase, MAPEG superfamily
H7R40_RS09165	COG1801	Protein of unknown function DUF72
H7R40_RS09170	COG1335	isochorismatase
H7R40_RS09180	COG0494	nUDIX hydrolase
H7R40_RS09205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7R40_RS09215	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
H7R40_RS09220	COG0739	heme binding
H7R40_RS09225	COG1560	Kdo2-lipid A biosynthetic process
H7R40_RS09235	COG1737	Transcriptional regulator
H7R40_RS09245	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H7R40_RS09250	COG0129	dihydroxy-acid dehydratase activity
H7R40_RS09255	COG0800	Aldolase
H7R40_RS09265	COG3141	response to X-ray
H7R40_RS09270	COG2979	Protein of unknown function (DUF533)
H7R40_RS09275	COG1770	oligopeptidase
H7R40_RS09280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7R40_RS09290	COG2372	response to copper ion
H7R40_RS09295	COG1276	copper resistance
H7R40_RS09310	COG2990	Protein conserved in bacteria
H7R40_RS09335	COG3008	intermembrane lipid transfer
H7R40_RS09340	COG2995	paraquat-inducible protein a
H7R40_RS09345	COG1956	GAF domain-containing protein
H7R40_RS09365	COG2814	Major facilitator Superfamily
H7R40_RS09370	COG1414	Transcriptional regulator
H7R40_RS09400	COG0768	penicillin binding
H7R40_RS09405	COG2226	methyltransferase
H7R40_RS09420	COG3716	PTS system mannose fructose sorbose family IID component
H7R40_RS09425	COG3715	PTS system
H7R40_RS09430	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R40_RS09430	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R40_RS09435	COG1253	flavin adenine dinucleotide binding
H7R40_RS09440	COG2200	EAL domain
H7R40_RS09445	COG1760	l-serine dehydratase
H7R40_RS09465	COG0251	oxidation-reduction process
H7R40_RS09470	COG1199	ATP-dependent helicase activity
H7R40_RS09480	COG3065	identical protein binding
H7R40_RS09490	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H7R40_RS09500	COG2894	cell division
H7R40_RS09515	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7R40_RS09545	COG2719	SpoVR family
H7R40_RS09570	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7R40_RS09580	COG4774	siderophore transport
H7R40_RS09595	COG2308	Evidence 4 Homologs of previously reported genes of
H7R40_RS09635	COG0583	DNA-binding transcription factor activity
H7R40_RS09640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7R40_RS09655	COG1882	Formate acetyltransferase
H7R40_RS09690	COG0583	DNA-binding transcription factor activity
H7R40_RS09725	COG0582	viral genome integration into host DNA
H7R40_RS09930	COG3772	lysozyme
H7R40_RS09950	COG3728	DNA packaging
H7R40_RS09950	COG5484	DNA packaging
H7R40_RS09955	COG5410	chromosome segregation
H7R40_RS10020	COG3646	Phage regulatory protein
H7R40_RS10030	COG1196	nuclear chromosome segregation
H7R40_RS10030	COG0739	heme binding
H7R40_RS10030	COG0741	lytic transglycosylase activity
H7R40_RS10125	COG3122	Protein conserved in bacteria
H7R40_RS10145	COG2885	chlorophyll binding
H7R40_RS10160	COG1388	LysM domain
H7R40_RS10220	COG0012	GTP binding
H7R40_RS10240	COG0659	secondary active sulfate transmembrane transporter activity
H7R40_RS10270	COG2890	protein-(glutamine-N5) methyltransferase activity
H7R40_RS10290	COG0387	Pfam Sodium calcium exchanger
H7R40_RS10295	COG4572	Cation transport regulator
H7R40_RS10300	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H7R40_RS10310	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H7R40_RS10315	COG3707	response regulator
H7R40_RS10320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R40_RS10330	COG1116	anion transmembrane transporter activity
H7R40_RS10335	COG2146	nitrite reductase [NAD(P)H] activity
H7R40_RS10335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R40_RS10340	COG0243	molybdopterin cofactor binding
H7R40_RS10345	COG4932	domain protein
H7R40_RS10350	COG2197	response regulator
H7R40_RS10355	COG3850	Histidine kinase
H7R40_RS10360	COG2223	nitrite transmembrane transporter activity
H7R40_RS10370	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H7R40_RS10375	COG1140	nitrate reductase beta subunit
H7R40_RS10380	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H7R40_RS10385	COG2181	nitrate reductase activity
H7R40_RS10395	COG1522	sequence-specific DNA binding
H7R40_RS10425	COG0788	formyltetrahydrofolate deformylase activity
H7R40_RS10435	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7R40_RS10440	COG0745	RESPONSE REGULATOR receiver
H7R40_RS10445	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7R40_RS10450	COG2916	Histone family protein nucleoid-structuring protein H-NS
H7R40_RS10460	COG1435	thymidine kinase activity
H7R40_RS10465	COG1454	alcohol dehydrogenase
H7R40_RS10465	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS10475	COG2095	MarC family integral membrane protein
H7R40_RS10480	COG4166	transmembrane transport
H7R40_RS10485	COG0601	transmembrane transport
H7R40_RS10490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R40_RS10495	COG0444	Belongs to the ABC transporter superfamily
H7R40_RS10505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7R40_RS10525	COG2353	YceI-like domain
H7R40_RS10535	COG2350	Protein conserved in bacteria
H7R40_RS10545	COG3001	Fructosamine kinase
H7R40_RS10555	COG1105	Belongs to the carbohydrate kinase PfkB family
H7R40_RS10560	COG3137	Salt-induced outer membrane protein
H7R40_RS10600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7R40_RS10600	COG0072	phenylalanine-tRNA ligase activity
H7R40_RS10620	COG0583	DNA-binding transcription factor activity
H7R40_RS10640	COG0386	Belongs to the glutathione peroxidase family
H7R40_RS10650	COG0791	NLP P60 protein
H7R40_RS10660	COG4256	Hemin uptake protein
H7R40_RS10665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7R40_RS10680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7R40_RS10680	COG0574	Belongs to the PEP-utilizing enzyme family
H7R40_RS10690	COG0628	permease
H7R40_RS10695	COG0277	FAD linked oxidase domain protein
H7R40_RS10695	COG0247	lactate metabolic process
H7R40_RS10700	COG2050	protein possibly involved in aromatic compounds catabolism
H7R40_RS10705	COG2261	transglycosylase associated protein
H7R40_RS10730	COG1120	ATPase activity
H7R40_RS10735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R40_RS10745	COG0583	DNA-binding transcription factor activity
H7R40_RS10770	COG1304	FMN binding
H7R40_RS10775	COG1309	transcriptional regulator
H7R40_RS10795	COG0316	Belongs to the HesB IscA family
H7R40_RS10800	COG0719	Fe-S assembly protein
H7R40_RS10805	COG0396	ATPase activity
H7R40_RS10810	COG0719	Fe-S assembly protein
H7R40_RS10825	COG1376	ErfK ybiS ycfS ynhG family protein
H7R40_RS10855	COG1309	transcriptional regulator
H7R40_RS10860	COG1082	Xylose isomerase domain protein TIM barrel
H7R40_RS10860	COG3185	4-Hydroxyphenylpyruvate dioxygenase
H7R40_RS10865	COG2271	Major facilitator Superfamily
H7R40_RS10870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7R40_RS10880	COG1120	ATPase activity
H7R40_RS10885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R40_RS10890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7R40_RS10895	COG1414	Transcriptional regulator
H7R40_RS10930	COG2814	Major facilitator Superfamily
H7R40_RS10950	COG0583	DNA-binding transcription factor activity
H7R40_RS10955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R40_RS10975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R40_RS10980	COG1116	anion transmembrane transporter activity
H7R40_RS10985	COG4774	siderophore transport
H7R40_RS10990	COG1120	ATPase activity
H7R40_RS10995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R40_RS11000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R40_RS11020	COG0765	amino acid transport
H7R40_RS11025	COG1126	abc transporter atp-binding protein
H7R40_RS11065	COG3383	formate dehydrogenase (NAD+) activity
H7R40_RS11070	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H7R40_RS11080	COG1175	transmembrane transport
H7R40_RS11110	COG4133	protoheme IX ABC transporter activity
H7R40_RS11115	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7R40_RS11120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7R40_RS11135	COG1138	Cytochrome C-type biogenesis protein
H7R40_RS11140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7R40_RS11145	COG4235	cytochrome complex assembly
H7R40_RS11145	COG3088	subunit of a heme lyase
H7R40_RS11165	COG5002	protein histidine kinase activity
H7R40_RS11165	COG3850	Histidine kinase
H7R40_RS11170	COG0745	RESPONSE REGULATOR receiver
H7R40_RS11185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R40_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS11220	COG2610	gluconate transmembrane transporter activity
H7R40_RS11225	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7R40_RS11235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7R40_RS11245	COG0583	DNA-binding transcription factor activity
H7R40_RS11265	COG0277	FAD linked oxidase domain protein
H7R40_RS11270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R40_RS11295	COG0402	S-adenosylhomocysteine deaminase activity
H7R40_RS11350	COG4608	Belongs to the ABC transporter superfamily
H7R40_RS11355	COG0444	Belongs to the ABC transporter superfamily
H7R40_RS11380	COG0346	lactoylglutathione lyase activity
H7R40_RS11385	COG1349	DNA-binding transcription factor activity
H7R40_RS11420	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H7R40_RS11440	COG0300	oxidoreductase activity
H7R40_RS11485	COG0307	riboflavin synthase, alpha
H7R40_RS11490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7R40_RS11495	COG2814	Major facilitator Superfamily
H7R40_RS11500	COG0583	DNA-binding transcription factor activity
H7R40_RS11515	COG2814	Major facilitator Superfamily
H7R40_RS11530	COG0791	NLP P60 protein
H7R40_RS11535	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H7R40_RS11545	COG0346	lactoylglutathione lyase activity
H7R40_RS11550	COG1902	pentaerythritol trinitrate reductase activity
H7R40_RS11555	COG1309	transcriptional regulator
H7R40_RS11560	COG3313	Fe-S protein
H7R40_RS11565	COG4989	oxidoreductase activity
H7R40_RS11570	COG2032	superoxide dismutase activity
H7R40_RS11575	COG1289	transmembrane transporter activity
H7R40_RS11580	COG1566	PFAM secretion protein HlyD family protein
H7R40_RS11595	COG3706	GGDEF domain
H7R40_RS11610	COG3895	Periplasmic Protein
H7R40_RS11625	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H7R40_RS11630	COG0625	glutathione transferase activity
H7R40_RS11640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7R40_RS11650	COG4659	FMN binding
H7R40_RS11685	COG2723	6-phospho-beta-galactosidase activity
H7R40_RS11695	COG0673	inositol 2-dehydrogenase activity
H7R40_RS11705	COG2814	Major facilitator Superfamily
H7R40_RS11725	COG3038	cytochrome b561
H7R40_RS11745	COG0583	DNA-binding transcription factor activity
H7R40_RS11750	COG3485	protocatechuate 3,4-dioxygenase
H7R40_RS11755	COG3485	protocatechuate 3,4-dioxygenase
H7R40_RS11760	COG5383	Protein conserved in bacteria
H7R40_RS11765	COG2272	Belongs to the type-B carboxylesterase lipase family
H7R40_RS11780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7R40_RS11785	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7R40_RS11790	COG1275	C4-dicarboxylate transporter malic acid transport protein
H7R40_RS11795	COG0500	methyltransferase
H7R40_RS11810	COG3708	Transcriptional regulator
H7R40_RS11810	COG2207	Transcriptional regulator
H7R40_RS11815	COG3135	benzoate transporter
H7R40_RS11820	COG1396	sequence-specific DNA binding
H7R40_RS11830	COG0826	peptidase U32
H7R40_RS11850	COG1294	oxidase, subunit
H7R40_RS11855	COG1271	oxidase subunit
H7R40_RS11860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R40_RS11870	COG3842	ATPase activity
H7R40_RS11875	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7R40_RS11880	COG1177	transmembrane transport
H7R40_RS11885	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS11920	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS11930	COG0747	negative chemotaxis
H7R40_RS11940	COG3238	Protein conserved in bacteria
H7R40_RS11945	COG1247	-acetyltransferase
H7R40_RS11955	COG2130	NADP-dependent
H7R40_RS11970	COG3691	Protein conserved in bacteria
H7R40_RS11980	COG4772	TonB-dependent receptor
H7R40_RS12005	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7R40_RS12010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R40_RS12015	COG1473	amidohydrolase
H7R40_RS12020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R40_RS12025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R40_RS12035	COG0765	amino acid transport
H7R40_RS12040	COG1126	abc transporter atp-binding protein
H7R40_RS12050	COG0625	glutathione transferase activity
H7R40_RS12060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R40_RS12065	COG3842	ATPase activity
H7R40_RS12070	COG1840	ABC-type Fe3 transport system, periplasmic component
H7R40_RS12075	COG1178	ABC-type Fe3 transport system permease component
H7R40_RS12080	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H7R40_RS12085	COG2181	nitrate reductase activity
H7R40_RS12090	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H7R40_RS12095	COG1140	nitrate reductase beta subunit
H7R40_RS12100	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H7R40_RS12120	COG1414	Transcriptional regulator
H7R40_RS12130	COG4829	muconolactone delta-isomerase
H7R40_RS12135	COG3485	protocatechuate 3,4-dioxygenase
H7R40_RS12145	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H7R40_RS12170	COG0437	4 iron, 4 sulfur cluster binding
H7R40_RS12175	COG2864	formate dehydrogenase
H7R40_RS12190	COG2326	polyphosphate kinase activity
H7R40_RS12200	COG2814	Major facilitator Superfamily
H7R40_RS12210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R40_RS12220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R40_RS12230	COG0747	negative chemotaxis
H7R40_RS12235	COG1064	alcohol dehydrogenase
H7R40_RS12250	COG0488	(ABC) transporter
H7R40_RS12295	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS12300	COG3729	General stress protein
H7R40_RS12310	COG3685	Protein conserved in bacteria
H7R40_RS12320	COG0366	Alpha amylase catalytic
H7R40_RS12330	COG2323	membrane
H7R40_RS12340	COG3111	PFAM Bacterial OB fold (BOF) protein
H7R40_RS12350	COG1764	response to oxidative stress
H7R40_RS12375	COG3781	membrane
H7R40_RS12380	COG0243	molybdopterin cofactor binding
H7R40_RS12385	COG0583	DNA-binding transcription factor activity
H7R40_RS12390	COG2814	Major facilitator Superfamily
H7R40_RS12395	COG1285	pathogenesis
H7R40_RS12410	COG0583	DNA-binding transcription factor activity
H7R40_RS12430	COG0519	Catalyzes the synthesis of GMP from XMP
H7R40_RS12430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7R40_RS12470	COG0596	Alpha beta hydrolase
H7R40_RS12480	COG2205	protein histidine kinase activity
H7R40_RS12495	COG0076	glutamate decarboxylase activity
H7R40_RS12500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7R40_RS12505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R40_RS12510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R40_RS12515	COG1116	anion transmembrane transporter activity
H7R40_RS12520	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7R40_RS12535	COG0673	inositol 2-dehydrogenase activity
H7R40_RS12545	COG1609	Transcriptional regulator
H7R40_RS12550	COG3706	GGDEF domain
H7R40_RS12555	COG0402	S-adenosylhomocysteine deaminase activity
H7R40_RS12560	COG1953	Uracil, thiamine, allantoin
H7R40_RS12595	COG1715	Restriction endonuclease
H7R40_RS12610	COG2207	Transcriptional regulator
H7R40_RS12625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7R40_RS12695	COG0765	amino acid transport
H7R40_RS12705	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H7R40_RS12715	COG2070	2-Nitropropane dioxygenase
H7R40_RS12720	COG0583	DNA-binding transcription factor activity
H7R40_RS12730	COG1902	pentaerythritol trinitrate reductase activity
H7R40_RS12735	COG4529	Protein conserved in bacteria
H7R40_RS12740	COG0477	Major facilitator Superfamily
H7R40_RS12785	COG2223	nitrite transmembrane transporter activity
H7R40_RS12795	COG1609	Transcriptional regulator
H7R40_RS12800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R40_RS12815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7R40_RS12825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7R40_RS12830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7R40_RS12830	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H7R40_RS12830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7R40_RS12845	COG0583	DNA-binding transcription factor activity
H7R40_RS12850	COG0583	DNA-binding transcription factor activity
H7R40_RS12855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7R40_RS12865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7R40_RS12880	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS12890	COG1609	Transcriptional regulator
H7R40_RS12920	COG1652	LysM domain
H7R40_RS12945	COG0456	acetyltransferase
H7R40_RS12945	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H7R40_RS12955	COG0667	Aldo Keto reductase
H7R40_RS12960	COG0667	Aldo Keto reductase
H7R40_RS12965	COG3386	PFAM SMP-30 Gluconolaconase
H7R40_RS12970	COG0667	Aldo Keto reductase
H7R40_RS12985	COG2801	Transposase and inactivated derivatives
H7R40_RS12990	COG1349	DNA-binding transcription factor activity
H7R40_RS13005	COG1349	DNA-binding transcription factor activity
H7R40_RS13015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R40_RS13020	COG0738	Major facilitator superfamily
H7R40_RS13045	COG0183	Belongs to the thiolase family
H7R40_RS13065	COG1929	Belongs to the glycerate kinase type-1 family
H7R40_RS13070	COG3835	regulator
H7R40_RS13090	COG2186	Transcriptional regulator
H7R40_RS13095	COG1263	PTS System
H7R40_RS13095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R40_RS13105	COG2814	Major facilitator Superfamily
H7R40_RS13110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R40_RS13110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R40_RS13125	COG2819	hydrolase of the alpha beta superfamily
H7R40_RS13130	COG5001	Diguanylate cyclase
H7R40_RS13130	COG3300	MHYT domain
H7R40_RS13165	COG3188	usher protein
H7R40_RS13175	COG1649	PFAM Uncharacterised BCR, COG1649
H7R40_RS13180	COG3550	peptidyl-serine autophosphorylation
H7R40_RS13185	COG1396	sequence-specific DNA binding
H7R40_RS13190	COG2351	hydroxyisourate hydrolase activity
H7R40_RS13195	COG3195	allantoin biosynthetic process
H7R40_RS13195	COG3648	Uricase
H7R40_RS13200	COG2233	PERMEase
H7R40_RS13230	COG2207	Transcriptional regulator
H7R40_RS13245	COG4628	conserved protein (DUF2132)
H7R40_RS13265	COG2011	ABC-type metal ion transport system permease component
H7R40_RS13270	COG2070	2-Nitropropane dioxygenase
H7R40_RS13280	COG0477	Major facilitator Superfamily
H7R40_RS13330	COG2199	diguanylate cyclase activity
H7R40_RS13345	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS13350	COG0583	DNA-binding transcription factor activity
H7R40_RS13360	COG0039	L-malate dehydrogenase activity
H7R40_RS13365	COG1349	DNA-binding transcription factor activity
H7R40_RS13370	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H7R40_RS13375	COG3395	kinase activity
H7R40_RS13385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7R40_RS13390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7R40_RS13395	COG2271	Major facilitator Superfamily
H7R40_RS13425	COG4977	sequence-specific DNA binding
H7R40_RS13435	COG0697	spore germination
H7R40_RS13440	COG2814	Major facilitator Superfamily
H7R40_RS13455	COG1129	ABC transporter
H7R40_RS13475	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7R40_RS13510	COG2223	nitrite transmembrane transporter activity
H7R40_RS13515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H7R40_RS13530	COG1349	DNA-binding transcription factor activity
H7R40_RS13540	COG3395	kinase activity
H7R40_RS13545	COG0235	Class ii aldolase
H7R40_RS13550	COG3622	Belongs to the hyi family
H7R40_RS13560	COG2207	Transcriptional regulator
H7R40_RS13560	COG3708	Transcriptional regulator
H7R40_RS13590	COG2200	EAL domain
H7R40_RS13595	COG1546	Belongs to the CinA family
H7R40_RS13600	COG0071	Belongs to the small heat shock protein (HSP20) family
H7R40_RS13630	COG2135	peptidase activity
H7R40_RS13635	COG2207	Transcriptional regulator
H7R40_RS13645	COG0339	signal peptide processing
H7R40_RS13650	COG4221	oxidoreductase activity
H7R40_RS13655	COG1802	Transcriptional regulator
H7R40_RS13660	COG0589	response to stress
H7R40_RS13665	COG0246	Mannitol dehydrogenase
H7R40_RS13670	COG2271	Major facilitator Superfamily
H7R40_RS13685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7R40_RS13700	COG0243	molybdopterin cofactor binding
H7R40_RS13705	COG0437	4 iron, 4 sulfur cluster binding
H7R40_RS13710	COG3302	dmso reductase anchor subunit
H7R40_RS13725	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H7R40_RS13730	COG1940	carbohydrate kinase activity
H7R40_RS13735	COG0583	DNA-binding transcription factor activity
H7R40_RS13740	COG2814	Major facilitator Superfamily
H7R40_RS13745	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H7R40_RS13755	COG3591	Belongs to the peptidase S1B family
H7R40_RS13775	COG0628	permease
H7R40_RS13805	COG0679	Auxin Efflux Carrier
H7R40_RS13815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7R40_RS13840	COG3290	protein histidine kinase activity
H7R40_RS13845	COG4565	transcriptional regulatory protein
H7R40_RS13865	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H7R40_RS13865	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H7R40_RS13875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7R40_RS13880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7R40_RS13890	COG0183	Belongs to the thiolase family
H7R40_RS13895	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7R40_RS13905	COG1414	Transcriptional regulator
H7R40_RS13910	COG2840	Smr protein MutS2
H7R40_RS13915	COG0583	DNA-binding transcription factor activity
H7R40_RS13925	COG1473	amidohydrolase
H7R40_RS13930	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H7R40_RS14015	COG0740	serine-type endopeptidase activity
H7R40_RS14065	COG3772	lysozyme
H7R40_RS14090	COG4725	Belongs to the MT-A70-like family
H7R40_RS14180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7R40_RS14195	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H7R40_RS14200	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H7R40_RS14215	COG0531	amino acid
H7R40_RS14225	COG3136	membrane protein required for alginate biosynthesis
H7R40_RS14230	COG0745	RESPONSE REGULATOR receiver
H7R40_RS14240	COG2205	protein histidine kinase activity
H7R40_RS14250	COG0114	fumarate hydratase activity
H7R40_RS14255	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H7R40_RS14255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H7R40_RS14260	COG1482	cell wall glycoprotein biosynthetic process
H7R40_RS14265	COG5339	Protein conserved in bacteria
H7R40_RS14270	COG1609	Transcriptional regulator
H7R40_RS14275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R40_RS14275	COG1263	PTS System
H7R40_RS14280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H7R40_RS14305	COG2391	methyltransferase activity
H7R40_RS14310	COG0425	Belongs to the sulfur carrier protein TusA family
H7R40_RS14315	COG5562	phage envelope protein
H7R40_RS14320	COG0401	homolog of Blt101
H7R40_RS14325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7R40_RS14330	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS14340	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H7R40_RS14345	COG0477	Major facilitator Superfamily
H7R40_RS14350	COG1113	amino acid transport
H7R40_RS14355	COG2988	succinylglutamate desuccinylase activity
H7R40_RS14360	COG3724	N-succinylarginine dihydrolase activity
H7R40_RS14365	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS14370	COG3138	arginine N-succinyltransferase
H7R40_RS14375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7R40_RS14385	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7R40_RS14390	COG0667	Aldo Keto reductase
H7R40_RS14395	COG0583	DNA-binding transcription factor activity
H7R40_RS14420	COG4122	O-methyltransferase activity
H7R40_RS14425	COG1643	Atp-dependent helicase
H7R40_RS14440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7R40_RS14445	COG3327	negative regulation of DNA-templated transcription, initiation
H7R40_RS14450	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H7R40_RS14455	COG0183	Belongs to the thiolase family
H7R40_RS14460	COG2050	protein possibly involved in aromatic compounds catabolism
H7R40_RS14465	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7R40_RS14470	COG1024	Enoyl-CoA hydratase
H7R40_RS14475	COG1024	Enoyl-CoA hydratase
H7R40_RS14480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R40_RS14485	COG2151	metal-sulfur cluster biosynthetic enzyme
H7R40_RS14490	COG3396	Phenylacetate-CoA oxygenase
H7R40_RS14495	COG3460	Phenylacetate-CoA oxygenase
H7R40_RS14500	COG3396	Phenylacetate-CoA oxygenase
H7R40_RS14505	COG2030	dehydratase
H7R40_RS14505	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS14525	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS14530	COG2207	Transcriptional regulator
H7R40_RS14535	COG3784	Protein of unknown function (DUF1318)
H7R40_RS14545	COG2911	Protein conserved in bacteria
H7R40_RS14550	COG0586	Pfam SNARE associated Golgi protein
H7R40_RS14555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7R40_RS14560	COG3187	Heat shock protein
H7R40_RS14565	COG3042	response to heat
H7R40_RS14570	COG0674	pyruvate-flavodoxin oxidoreductase activity
H7R40_RS14570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7R40_RS14570	COG1013	pyruvate-flavodoxin oxidoreductase activity
H7R40_RS14570	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H7R40_RS14575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H7R40_RS14585	COG0589	response to stress
H7R40_RS14595	COG0513	Belongs to the DEAD box helicase family
H7R40_RS14605	COG1349	DNA-binding transcription factor activity
H7R40_RS14610	COG0673	inositol 2-dehydrogenase activity
H7R40_RS14625	COG1113	amino acid transport
H7R40_RS14630	COG1522	sequence-specific DNA binding
H7R40_RS14640	COG1448	Aminotransferase
H7R40_RS14645	COG2011	ABC-type metal ion transport system permease component
H7R40_RS14660	COG0436	Aminotransferase
H7R40_RS14665	COG0604	alcohol dehydrogenase
H7R40_RS14695	COG0583	DNA-binding transcription factor activity
H7R40_RS14715	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS14720	COG1309	transcriptional regulator
H7R40_RS14725	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS14800	COG2885	chlorophyll binding
H7R40_RS14825	COG0693	protein deglycase activity
H7R40_RS14830	COG1078	dGTPase activity
H7R40_RS14835	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS14840	COG0583	DNA-binding transcription factor activity
H7R40_RS14855	COG0656	L-ascorbic acid biosynthetic process
H7R40_RS14885	COG4166	transmembrane transport
H7R40_RS14895	COG2866	Carboxypeptidase
H7R40_RS14900	COG4948	Mandelate Racemase Muconate Lactonizing
H7R40_RS14905	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H7R40_RS14910	COG3180	Ammonia monooxygenase
H7R40_RS14920	COG1486	melibiose metabolic process
H7R40_RS14925	COG0583	DNA-binding transcription factor activity
H7R40_RS14935	COG3106	COG3106 Predicted ATPase
H7R40_RS14945	COG1983	PspC domain protein
H7R40_RS14955	COG1842	Phage shock protein A
H7R40_RS14960	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7R40_RS14970	COG1473	amidohydrolase
H7R40_RS14985	COG0702	epimerase
H7R40_RS15000	COG2135	peptidase activity
H7R40_RS15010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7R40_RS15015	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7R40_RS15065	COG1196	nuclear chromosome segregation
H7R40_RS15165	COG5484	DNA packaging
H7R40_RS15165	COG3728	DNA packaging
H7R40_RS15270	COG0305	Participates in initiation and elongation during chromosome replication
H7R40_RS15370	COG4171	peptide transport system, permease
H7R40_RS15385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H7R40_RS15395	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H7R40_RS15400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7R40_RS15400	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7R40_RS15415	COG1349	DNA-binding transcription factor activity
H7R40_RS15425	COG0023	Translation Initiation Factor
H7R40_RS15435	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H7R40_RS15440	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
H7R40_RS15445	COG0671	phosphoesterase, PA-phosphatase related
H7R40_RS15455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H7R40_RS15480	COG0616	signal peptide processing
H7R40_RS15490	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS15495	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H7R40_RS15505	COG0583	DNA-binding transcription factor activity
H7R40_RS15515	COG0009	L-threonylcarbamoyladenylate synthase
H7R40_RS15525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H7R40_RS15530	COG0512	Glutamine amidotransferase of anthranilate synthase
H7R40_RS15530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7R40_RS15535	COG0134	indole-3-glycerol-phosphate synthase activity
H7R40_RS15535	COG0135	phosphoribosylanthranilate isomerase activity
H7R40_RS15590	COG4774	siderophore transport
H7R40_RS15600	COG3047	cAMP biosynthetic process
H7R40_RS15605	COG0727	PFAM Uncharacterised protein family (UPF0153)
H7R40_RS15635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R40_RS15640	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS15645	COG1988	membrane-bound metal-dependent
H7R40_RS15650	COG1823	symporter activity
H7R40_RS15660	COG0753	catalase activity
H7R40_RS15670	COG1486	melibiose metabolic process
H7R40_RS15675	COG1917	Cupin 2, conserved barrel domain protein
H7R40_RS15675	COG2169	Transcriptional regulator
H7R40_RS15680	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7R40_RS15685	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R40_RS15695	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R40_RS15700	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7R40_RS15710	COG0322	excinuclease ABC activity
H7R40_RS15715	COG3678	ATP-independent chaperone mediated protein folding
H7R40_RS15725	COG3724	N-succinylarginine dihydrolase activity
H7R40_RS15735	COG3138	arginine N-succinyltransferase
H7R40_RS15745	COG0708	Exodeoxyribonuclease III
H7R40_RS15750	COG0398	Pfam SNARE associated Golgi protein
H7R40_RS15755	COG0398	Pfam SNARE associated Golgi protein
H7R40_RS15760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7R40_RS15765	COG4134	Bacterial extracellular solute-binding protein
H7R40_RS15770	COG4135	transport system, permease component
H7R40_RS15775	COG4136	ATPase activity
H7R40_RS15780	COG2897	thiosulfate sulfurtransferase activity
H7R40_RS15785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H7R40_RS15790	COG0494	nUDIX hydrolase
H7R40_RS15795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7R40_RS15800	COG3321	synthase
H7R40_RS15800	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS15800	COG0604	alcohol dehydrogenase
H7R40_RS15805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7R40_RS15810	COG0709	Synthesizes selenophosphate from selenide and ATP
H7R40_RS15820	COG0778	Nitroreductase
H7R40_RS15825	COG0616	signal peptide processing
H7R40_RS15830	COG0252	asparaginase activity
H7R40_RS15835	COG1335	isochorismatase
H7R40_RS15850	COG3139	Protein of unknown function (DUF1315)
H7R40_RS15870	COG0656	L-ascorbic acid biosynthetic process
H7R40_RS15875	COG3713	MltA-interacting MipA family protein
H7R40_RS15880	COG2766	serine protein kinase
H7R40_RS15920	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS15925	COG0583	DNA-binding transcription factor activity
H7R40_RS15930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7R40_RS15935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7R40_RS15945	COG0859	PFAM glycosyl transferase family 9
H7R40_RS15950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H7R40_RS15960	COG2207	Transcriptional regulator
H7R40_RS15965	COG2807	transmembrane transport
H7R40_RS15970	COG0504	CTP synthase activity
H7R40_RS15975	COG1683	Conserved Protein
H7R40_RS15980	COG3189	MarR family transcriptional regulator
H7R40_RS15985	COG3042	response to heat
H7R40_RS15990	COG2199	diguanylate cyclase activity
H7R40_RS15990	COG2203	Gaf domain
H7R40_RS16010	COG3182	Iron-regulated membrane protein
H7R40_RS16020	COG1560	Kdo2-lipid A biosynthetic process
H7R40_RS16030	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H7R40_RS16035	COG3706	GGDEF domain
H7R40_RS16040	COG0583	DNA-binding transcription factor activity
H7R40_RS16045	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H7R40_RS16075	COG1294	oxidase, subunit
H7R40_RS16080	COG1271	oxidase subunit
H7R40_RS16085	COG3546	catalase activity
H7R40_RS16090	COG3685	Protein conserved in bacteria
H7R40_RS16095	COG3685	Protein conserved in bacteria
H7R40_RS16100	COG3729	General stress protein
H7R40_RS16110	COG1063	alcohol dehydrogenase
H7R40_RS16115	COG3813	Protein conserved in bacteria
H7R40_RS16135	COG0640	Transcriptional regulator
H7R40_RS16140	COG0538	isocitrate dehydrogenase activity
H7R40_RS16225	COG0616	signal peptide processing
H7R40_RS16240	COG4626	Terminase
H7R40_RS16240	COG1802	Transcriptional regulator
H7R40_RS16285	COG3772	lysozyme
H7R40_RS16310	COG1403	HNH endonuclease
H7R40_RS16415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7R40_RS16425	COG0582	viral genome integration into host DNA
H7R40_RS16430	COG0538	isocitrate dehydrogenase activity
H7R40_RS16435	COG1187	pseudouridine synthase activity
H7R40_RS16455	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H7R40_RS16475	COG2205	protein histidine kinase activity
H7R40_RS16480	COG2850	peptidyl-arginine hydroxylation
H7R40_RS16500	COG1177	transmembrane transport
H7R40_RS16515	COG0318	PFAM AMP-dependent synthetase and ligase
H7R40_RS16520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7R40_RS16525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7R40_RS16530	COG0698	ribose 5-phosphate isomerase
H7R40_RS16545	COG3395	kinase activity
H7R40_RS16560	COG2390	Transcriptional regulator
H7R40_RS16570	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H7R40_RS16580	COG4591	ABC-type transport system involved in lipoprotein release permease component
H7R40_RS16590	COG4591	ABC-type transport system involved in lipoprotein release permease component
H7R40_RS16600	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7R40_RS16605	COG1388	LysM domain
H7R40_RS16605	COG1376	ErfK ybiS ycfS ynhG family protein
H7R40_RS16620	COG1309	transcriptional regulator
H7R40_RS16635	COG3134	Outer membrane lipoprotein
H7R40_RS16640	COG1252	NADH dehydrogenase
H7R40_RS16665	COG5633	Lipoprotein
H7R40_RS16670	COG0537	adenosine 5'-monophosphoramidase activity
H7R40_RS16680	COG0084	hydrolase, TatD family'
H7R40_RS16685	COG0470	DNA polymerase III
H7R40_RS16695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7R40_RS16700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7R40_RS16705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7R40_RS16720	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7R40_RS16740	COG1399	metal-binding, possibly nucleic acid-binding protein
H7R40_RS16760	COG1530	ribonuclease E activity
H7R40_RS16765	COG0583	DNA-binding transcription factor activity
H7R40_RS16770	COG2814	Major facilitator Superfamily
H7R40_RS16790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7R40_RS16835	COG1560	Kdo2-lipid A biosynthetic process
H7R40_RS16860	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H7R40_RS16875	COG5645	(Lipo)protein
H7R40_RS16910	COG3381	protein complex oligomerization
H7R40_RS16930	COG0583	DNA-binding transcription factor activity
H7R40_RS16940	COG1335	isochorismatase
H7R40_RS17015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7R40_RS17020	COG1702	phosphate starvation-inducible protein PhoH
H7R40_RS17040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7R40_RS17050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7R40_RS17065	COG1309	transcriptional regulator
H7R40_RS17100	COG2233	PERMEase
H7R40_RS17110	COG3729	General stress protein
H7R40_RS17140	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS17155	COG0531	amino acid
H7R40_RS17160	COG0174	glutamine synthetase
H7R40_RS17165	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H7R40_RS17170	COG1396	sequence-specific DNA binding
H7R40_RS17170	COG1917	Cupin 2, conserved barrel domain protein
H7R40_RS17175	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS17180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7R40_RS17185	COG0583	DNA-binding transcription factor activity
H7R40_RS17190	COG0473	3-isopropylmalate dehydrogenase activity
H7R40_RS17195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7R40_RS17200	COG4638	Rieske (2fe-2S)
H7R40_RS17205	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS17210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R40_RS17235	COG3039	Transposase
H7R40_RS17240	COG0670	Belongs to the BI1 family
H7R40_RS17255	COG2207	Transcriptional regulator
H7R40_RS17260	COG1881	PFAM PEBP family protein
H7R40_RS17285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R40_RS17290	COG2274	protein secretion by the type I secretion system
H7R40_RS17305	COG1832	CoA-binding protein
H7R40_RS17315	COG0210	DNA helicase
H7R40_RS17320	COG3304	Inner membrane component domain
H7R40_RS17325	COG1289	transmembrane transporter activity
H7R40_RS17330	COG3070	regulator of competence-specific genes
H7R40_RS17350	COG1067	ATP-dependent peptidase activity
H7R40_RS17360	COG3130	regulation of translation
H7R40_RS17365	COG3009	Protein conserved in bacteria
H7R40_RS17370	COG3008	intermembrane lipid transfer
H7R40_RS17370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H7R40_RS17375	COG2995	paraquat-inducible protein a
H7R40_RS17380	COG0488	(ABC) transporter
H7R40_RS17390	COG0633	Ferredoxin
H7R40_RS17390	COG3217	Mosc domain protein beta barrel domain protein
H7R40_RS17405	COG0431	NADPH-dependent FMN reductase
H7R40_RS17410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R40_RS17415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R40_RS17420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R40_RS17430	COG0308	aminopeptidase N
H7R40_RS17440	COG1473	amidohydrolase
H7R40_RS17450	COG0814	amino acid
H7R40_RS17475	COG1448	Aminotransferase
H7R40_RS17480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7R40_RS17485	COG3108	Peptidase M15
H7R40_RS17490	COG2989	Protein conserved in bacteria
H7R40_RS17500	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
H7R40_RS17510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H7R40_RS17515	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H7R40_RS17520	COG3173	Aminoglycoside phosphotransferase
H7R40_RS17535	COG3214	Protein conserved in bacteria
H7R40_RS17550	COG2333	competence protein COMEC
H7R40_RS17550	COG0658	competence protein
H7R40_RS17560	COG0539	negative regulation of cytoplasmic translation
H7R40_RS17580	COG2323	membrane
H7R40_RS17585	COG1944	ATP diphosphatase activity
H7R40_RS17590	COG2116	formate transmembrane transporter activity
H7R40_RS17595	COG1882	Formate acetyltransferase
H7R40_RS17600	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H7R40_RS17605	COG0477	Major facilitator Superfamily
H7R40_RS17610	COG3302	dmso reductase anchor subunit
H7R40_RS17615	COG0437	4 iron, 4 sulfur cluster binding
H7R40_RS17620	COG0243	molybdopterin cofactor binding
H7R40_RS17630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7R40_RS17640	COG1674	ftsk spoiiie
H7R40_RS17640	COG1178	ABC-type Fe3 transport system permease component
H7R40_RS17650	COG0492	ferredoxin-NADP+ reductase activity
H7R40_RS17655	COG4988	ABC transporter
H7R40_RS17660	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H7R40_RS17675	COG0542	response to heat
H7R40_RS17685	COG1278	Cold shock
H7R40_RS17695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R40_RS17700	COG3593	DNA synthesis involved in DNA repair
H7R40_RS17710	COG2431	L-lysine efflux transmembrane transporter activity
H7R40_RS17720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R40_RS17730	COG0028	Belongs to the TPP enzyme family
H7R40_RS17735	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
H7R40_RS17740	COG0702	epimerase
H7R40_RS17745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7R40_RS17750	COG3023	N-Acetylmuramoyl-L-alanine amidase
H7R40_RS17755	COG2203	Gaf domain
H7R40_RS17755	COG5001	Diguanylate cyclase
H7R40_RS17755	COG4251	negative regulation of phosphorylation
H7R40_RS17755	COG3706	GGDEF domain
H7R40_RS17765	COG1126	abc transporter atp-binding protein
H7R40_RS17770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R40_RS17775	COG4215	(ABC) transporter
H7R40_RS17780	COG4160	amino acid transport
H7R40_RS17785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R40_RS17790	COG5002	protein histidine kinase activity
H7R40_RS17795	COG0745	RESPONSE REGULATOR receiver
H7R40_RS17810	COG1177	transmembrane transport
H7R40_RS17815	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7R40_RS17820	COG3842	ATPase activity
H7R40_RS17825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H7R40_RS17840	COG0778	Nitroreductase
H7R40_RS17865	COG3226	Transcriptional regulator
H7R40_RS17870	COG0738	Major facilitator superfamily
H7R40_RS17875	COG0561	phosphatase activity
H7R40_RS17880	COG2814	Major facilitator Superfamily
H7R40_RS17885	COG0671	phosphoesterase, PA-phosphatase related
H7R40_RS17890	COG1349	DNA-binding transcription factor activity
H7R40_RS17895	COG1686	Belongs to the peptidase S11 family
H7R40_RS17905	COG0625	glutathione transferase activity
H7R40_RS17910	COG2133	pyrroloquinoline quinone binding
H7R40_RS17920	COG2223	nitrite transmembrane transporter activity
H7R40_RS17940	COG0747	negative chemotaxis
H7R40_RS17955	COG0303	'Molybdopterin
H7R40_RS17960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7R40_RS17965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H7R40_RS17970	COG1882	Formate acetyltransferase
H7R40_RS17975	COG0561	phosphatase activity
H7R40_RS17985	COG1609	Transcriptional regulator
H7R40_RS17990	COG2271	Major facilitator Superfamily
H7R40_RS18000	COG0488	(ABC) transporter
H7R40_RS18005	COG2365	Tyrosine phosphatase family
H7R40_RS18010	COG1376	ErfK ybiS ycfS ynhG family protein
H7R40_RS18015	COG2188	Transcriptional regulator
H7R40_RS18020	COG2723	6-phospho-beta-galactosidase activity
H7R40_RS18025	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H7R40_RS18040	COG2194	sulfuric ester hydrolase activity
H7R40_RS18045	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H7R40_RS18060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R40_RS18065	COG0765	amino acid transport
H7R40_RS18070	COG1126	abc transporter atp-binding protein
H7R40_RS18075	COG0668	transmembrane transport
H7R40_RS18085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R40_RS18095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7R40_RS18105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7R40_RS18110	COG1199	ATP-dependent helicase activity
H7R40_RS18115	COG0513	Belongs to the DEAD box helicase family
H7R40_RS18120	COG3958	Transketolase
H7R40_RS18125	COG3959	Transketolase, thiamine diphosphate binding domain
H7R40_RS18130	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS18135	COG2271	Major facilitator Superfamily
H7R40_RS18145	COG0583	DNA-binding transcription factor activity
H7R40_RS18150	COG1309	transcriptional regulator
H7R40_RS18155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R40_RS18160	COG1131	(ABC) transporter
H7R40_RS18165	COG0842	Transport permease protein
H7R40_RS18170	COG0842	Transport permease protein
H7R40_RS18180	COG3568	Endonuclease Exonuclease Phosphatase
H7R40_RS18185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7R40_RS18190	COG0392	lysyltransferase activity
H7R40_RS18195	COG0670	Belongs to the BI1 family
H7R40_RS18200	COG0314	molybdopterin synthase activity
H7R40_RS18205	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H7R40_RS18215	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7R40_RS18235	COG0745	RESPONSE REGULATOR receiver
H7R40_RS18240	COG0642	Histidine kinase
H7R40_RS18265	COG2226	methyltransferase
H7R40_RS18280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7R40_RS18285	COG1881	PFAM PEBP family protein
H7R40_RS18325	COG4677	pectinesterase activity
H7R40_RS18335	COG0589	response to stress
H7R40_RS18340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R40_RS18375	COG0789	Transcriptional regulator
H7R40_RS18380	COG2200	EAL domain
H7R40_RS18405	COG0561	phosphatase activity
H7R40_RS18415	COG4149	molybdate abc transporter
H7R40_RS18420	COG0725	ABC transporter, periplasmic molybdate-binding protein
H7R40_RS18430	COG3585	molybdate ion transport
H7R40_RS18430	COG2005	Transcriptional regulator
H7R40_RS18435	COG1119	ATPase activity
H7R40_RS18445	COG1085	galactose-1-phosphate uridylyltransferase
H7R40_RS18455	COG2017	converts alpha-aldose to the beta-anomer
H7R40_RS18465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7R40_RS18480	COG3201	nicotinamide mononucleotide transporter
H7R40_RS18485	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H7R40_RS18535	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
H7R40_RS18540	COG2885	chlorophyll binding
H7R40_RS18550	COG3064	Membrane
H7R40_RS18555	COG0848	biopolymer transport protein
H7R40_RS18560	COG0811	peptide transport
H7R40_RS18565	COG0824	Thioesterase
H7R40_RS18570	COG3790	cyd operon protein YbgE
H7R40_RS18575	COG4890	Cyd operon protein YbgT
H7R40_RS18580	COG1294	oxidase, subunit
H7R40_RS18585	COG1271	oxidase subunit
H7R40_RS18590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7R40_RS18600	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7R40_RS18605	COG0567	Dehydrogenase, E1 component
H7R40_RS18610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7R40_RS18615	COG1053	succinate dehydrogenase
H7R40_RS18620	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H7R40_RS18625	COG2009	succinate dehydrogenase
H7R40_RS18660	COG1984	allophanate hydrolase subunit 2
H7R40_RS18665	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H7R40_RS18680	COG0415	Belongs to the DNA photolyase family
H7R40_RS18710	COG2205	protein histidine kinase activity
H7R40_RS18715	COG0745	RESPONSE REGULATOR receiver
H7R40_RS18725	COG0033	Phosphoglucomutase
H7R40_RS18735	COG0596	Alpha beta hydrolase
H7R40_RS18750	COG0735	belongs to the Fur family
H7R40_RS18790	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H7R40_RS18795	COG1940	carbohydrate kinase activity
H7R40_RS18795	COG1846	Transcriptional regulator
H7R40_RS18800	COG0647	UMP catabolic process
H7R40_RS18805	COG0367	asparagine synthase
H7R40_RS18845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R40_RS18855	COG1702	phosphate starvation-inducible protein PhoH
H7R40_RS18880	COG0765	amino acid transport
H7R40_RS18885	COG0765	amino acid transport
H7R40_RS18890	COG1126	abc transporter atp-binding protein
H7R40_RS18905	COG2888	peptidyl-tyrosine sulfation
H7R40_RS18920	COG1466	dna polymerase III delta subunit
H7R40_RS18935	COG0799	negative regulation of ribosome biogenesis
H7R40_RS18945	COG0768	penicillin binding
H7R40_RS18950	COG0772	Belongs to the SEDS family
H7R40_RS18955	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7R40_RS18960	COG1686	Belongs to the peptidase S11 family
H7R40_RS18975	COG0583	DNA-binding transcription factor activity
H7R40_RS18990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7R40_RS19010	COG3069	C4-dicarboxylate transmembrane transporter activity
H7R40_RS19015	COG3719	Belongs to the RNase T2 family
H7R40_RS19020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7R40_RS19040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7R40_RS19045	COG0583	DNA-binding transcription factor activity
H7R40_RS19050	COG3969	phosphoadenosine phosphosulfate
H7R40_RS19055	COG1475	DNA binding
H7R40_RS19060	COG0436	Aminotransferase
H7R40_RS19085	COG1129	ABC transporter
H7R40_RS19090	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS19095	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS19105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7R40_RS19120	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H7R40_RS19130	COG0402	S-adenosylhomocysteine deaminase activity
H7R40_RS19140	COG0483	inositol monophosphate 1-phosphatase activity
H7R40_RS19145	COG2271	Major facilitator Superfamily
H7R40_RS19175	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS19180	COG1129	ABC transporter
H7R40_RS19185	COG0371	Dehydrogenase
H7R40_RS19190	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS19205	COG2879	small protein
H7R40_RS19210	COG1966	Carbon starvation protein
H7R40_RS19220	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS19225	COG3433	isochorismatase activity
H7R40_RS19225	COG1535	isochorismatase
H7R40_RS19230	COG1021	2,3-dihydroxybenzoate-AMP ligase
H7R40_RS19235	COG1169	isochorismate synthase
H7R40_RS19240	COG4592	Periplasmic binding protein
H7R40_RS19250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R40_RS19255	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R40_RS19260	COG1120	ATPase activity
H7R40_RS19265	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H7R40_RS19265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7R40_RS19270	COG3251	PFAM MbtH domain protein
H7R40_RS19275	COG2382	esterase
H7R40_RS19280	COG4771	TonB-dependent receptor
H7R40_RS19290	COG1879	ABC-type sugar transport system periplasmic component
H7R40_RS19300	COG1129	ABC transporter
H7R40_RS19305	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS19310	COG5464	transposase or invertase
H7R40_RS19315	COG2390	Transcriptional regulator
H7R40_RS19320	COG3959	Transketolase, thiamine diphosphate binding domain
H7R40_RS19325	COG3958	Transketolase
H7R40_RS19335	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7R40_RS19345	COG0583	DNA-binding transcription factor activity
H7R40_RS19350	COG0668	transmembrane transport
H7R40_RS19365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7R40_RS19390	COG0747	negative chemotaxis
H7R40_RS19395	COG0601	transmembrane transport
H7R40_RS19400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R40_RS19405	COG0444	Belongs to the ABC transporter superfamily
H7R40_RS19410	COG4608	Belongs to the ABC transporter superfamily
H7R40_RS19425	COG0656	L-ascorbic acid biosynthetic process
H7R40_RS19440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7R40_RS19445	COG4221	oxidoreductase activity
H7R40_RS19455	COG4215	(ABC) transporter
H7R40_RS19460	COG0765	amino acid transport
H7R40_RS19465	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
H7R40_RS19480	COG0697	spore germination
H7R40_RS19495	COG4608	Belongs to the ABC transporter superfamily
H7R40_RS19500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R40_RS19510	COG4166	transmembrane transport
H7R40_RS19520	COG3698	Phosphodiester glycosidase
H7R40_RS19560	COG2315	Protein conserved in bacteria
H7R40_RS19565	COG0778	Nitroreductase
H7R40_RS19575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R40_RS19585	COG3716	PTS system mannose fructose sorbose family IID component
H7R40_RS19590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H7R40_RS19595	COG2222	sugar isomerase
H7R40_RS19600	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H7R40_RS19600	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7R40_RS19615	COG0477	Major facilitator Superfamily
H7R40_RS19620	COG0668	transmembrane transport
H7R40_RS19625	COG1609	Transcriptional regulator
H7R40_RS19635	COG0673	inositol 2-dehydrogenase activity
H7R40_RS19645	COG2211	Major facilitator Superfamily
H7R40_RS19650	COG1113	amino acid transport
H7R40_RS19665	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS19670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7R40_RS19680	COG0531	amino acid
H7R40_RS19695	COG4680	protein conserved in bacteria
H7R40_RS19735	COG0667	Aldo Keto reductase
H7R40_RS19740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R40_RS19745	COG1473	amidohydrolase
H7R40_RS19775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R40_RS19780	COG1120	ATPase activity
H7R40_RS19785	COG1566	PFAM secretion protein HlyD family protein
H7R40_RS19830	COG4211	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS19835	COG1129	ABC transporter
H7R40_RS19880	COG3104	oligopeptide transport
H7R40_RS19885	COG1982	Orn Lys Arg decarboxylase major
H7R40_RS19890	COG0531	amino acid
H7R40_RS19895	COG3710	Transcriptional regulator
H7R40_RS19905	COG1560	Kdo2-lipid A biosynthetic process
H7R40_RS19950	COG2501	S4 domain
H7R40_RS19960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H7R40_RS19975	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H7R40_RS19980	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7R40_RS20000	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H7R40_RS20005	COG4181	ATPase activity
H7R40_RS20010	COG2755	lipolytic protein G-D-S-L family
H7R40_RS20015	COG0300	oxidoreductase activity
H7R40_RS20020	COG3118	belongs to the thioredoxin family
H7R40_RS20025	COG0390	transport system, permease component
H7R40_RS20030	COG4619	ABC transporter
H7R40_RS20035	COG0330	HflC and HflK could
H7R40_RS20040	COG1585	Membrane protein implicated in regulation of membrane protease activity
H7R40_RS20055	COG3735	TraB family
H7R40_RS20060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H7R40_RS20070	COG2223	nitrite transmembrane transporter activity
H7R40_RS20075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7R40_RS20075	COG4651	solute:proton antiporter activity
H7R40_RS20080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R40_RS20120	COG2832	Protein of unknown function (DUF454)
H7R40_RS20125	COG3923	Primosomal replication protein n
H7R40_RS20140	COG3264	Mechanosensitive ion channel
H7R40_RS20140	COG1196	nuclear chromosome segregation
H7R40_RS20145	COG1309	transcriptional regulator
H7R40_RS20150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R40_RS20155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R40_RS20170	COG0110	maltose O-acetyltransferase activity
H7R40_RS20220	COG1874	Beta-galactosidase
H7R40_RS20225	COG3867	Arabinogalactan endo-beta-1,4-galactanase
H7R40_RS20230	COG3833	ABC-type maltose transport systems, permease component
H7R40_RS20235	COG1175	transmembrane transport
H7R40_RS20240	COG2182	Extracellular solute-binding protein
H7R40_RS20265	COG2364	Membrane
H7R40_RS20325	COG3695	enzyme binding
H7R40_RS20330	COG3126	Type III secretion system lipoprotein chaperone (YscW)
H7R40_RS20335	COG1946	Acyl-CoA thioesterase
H7R40_RS20340	COG0004	ammonium transporteR
H7R40_RS20345	COG0347	Belongs to the P(II) protein family
H7R40_RS20350	COG1132	(ABC) transporter
H7R40_RS20355	COG1132	(ABC) transporter
H7R40_RS20360	COG1522	sequence-specific DNA binding
H7R40_RS20375	COG4533	DNA binding
H7R40_RS20385	COG0824	Thioesterase
H7R40_RS20390	COG1555	photosystem II stabilization
H7R40_RS20395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7R40_RS20400	COG0776	regulation of translation
H7R40_RS20405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H7R40_RS20425	COG0271	Belongs to the BolA IbaG family
H7R40_RS20430	COG3056	Lipoprotein
H7R40_RS20435	COG2223	nitrite transmembrane transporter activity
H7R40_RS20440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7R40_RS20445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7R40_RS20450	COG1845	cytochrome c oxidase, subunit III
H7R40_RS20455	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7R40_RS20470	COG1414	Transcriptional regulator
H7R40_RS20475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7R40_RS20480	COG1053	succinate dehydrogenase
H7R40_RS20490	COG1053	succinate dehydrogenase
H7R40_RS20505	COG0673	inositol 2-dehydrogenase activity
H7R40_RS20510	COG2814	Major facilitator Superfamily
H7R40_RS20520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7R40_RS20525	COG0693	protein deglycase activity
H7R40_RS20545	COG0142	geranyltranstransferase activity
H7R40_RS20555	COG0667	Aldo Keto reductase
H7R40_RS20560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7R40_RS20580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7R40_RS20580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7R40_RS20590	COG4238	major outer membrane lipoprotein
H7R40_RS20610	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7R40_RS20615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7R40_RS20620	COG1862	Preprotein translocase
H7R40_RS20645	COG0450	alkyl hydroperoxide reductase
H7R40_RS20650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R40_RS20665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R40_RS20675	COG1228	amidohydrolase
H7R40_RS20685	COG1335	isochorismatase
H7R40_RS20690	COG0583	DNA-binding transcription factor activity
H7R40_RS20695	COG0366	Alpha amylase catalytic
H7R40_RS20720	COG0420	3'-5' exonuclease activity
H7R40_RS20725	COG0419	ATPase involved in DNA repair
H7R40_RS20730	COG1940	carbohydrate kinase activity
H7R40_RS20745	COG4126	flavin adenine dinucleotide binding
H7R40_RS20755	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7R40_RS20760	COG3416	Protein conserved in bacteria
H7R40_RS20770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7R40_RS20780	COG1785	Belongs to the alkaline phosphatase family
H7R40_RS20820	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H7R40_RS20825	COG1335	isochorismatase
H7R40_RS20830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7R40_RS20835	COG0113	porphobilinogen synthase activity
H7R40_RS20845	COG2175	clavaminate synthase activity
H7R40_RS20850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R40_RS20855	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H7R40_RS20860	COG4521	taurine ABC transporter
H7R40_RS20865	COG2040	homocysteine
H7R40_RS20870	COG0833	amino acid
H7R40_RS20885	COG4303	Ethanolamine ammonia lyase large subunit
H7R40_RS20890	COG4302	ethanolamine ammonia-lyase activity
H7R40_RS20930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R40_RS20935	COG1126	abc transporter atp-binding protein
H7R40_RS20940	COG4597	amino acid ABC transporter
H7R40_RS20945	COG0765	amino acid transport
H7R40_RS20960	COG3188	usher protein
H7R40_RS20985	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H7R40_RS20995	COG3639	organic phosphonate transmembrane transporter activity
H7R40_RS21015	COG0791	NLP P60 protein
H7R40_RS21050	COG3188	usher protein
H7R40_RS21055	COG3121	Chaperone
H7R40_RS21060	COG3539	Fimbrial protein
H7R40_RS21080	COG3710	Transcriptional regulator
H7R40_RS21110	COG2200	EAL domain
H7R40_RS21130	COG3121	Chaperone
H7R40_RS21155	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H7R40_RS21170	COG0579	oxidoreductase
H7R40_RS21175	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS21180	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7R40_RS21185	COG1113	amino acid transport
H7R40_RS21190	COG1802	Transcriptional regulator
H7R40_RS21210	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7R40_RS21215	COG0454	-acetyltransferase
H7R40_RS21230	COG2991	Protein conserved in bacteria
H7R40_RS21245	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H7R40_RS21250	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H7R40_RS21265	COG3034	peptidoglycan biosynthetic process
H7R40_RS21270	COG0121	glutamine amidotransferase
H7R40_RS21280	COG1960	acyl-CoA dehydrogenase activity
H7R40_RS21285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7R40_RS21295	COG0583	DNA-binding transcription factor activity
H7R40_RS21305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7R40_RS21315	COG2226	methyltransferase
H7R40_RS21325	COG0741	lytic transglycosylase activity
H7R40_RS21325	COG1388	LysM domain
H7R40_RS21330	COG2226	methyltransferase
H7R40_RS21340	COG2814	Major facilitator Superfamily
H7R40_RS21345	COG0583	DNA-binding transcription factor activity
H7R40_RS21350	COG0656	L-ascorbic acid biosynthetic process
H7R40_RS21385	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H7R40_RS21395	COG2011	ABC-type metal ion transport system permease component
H7R40_RS21400	COG1464	Belongs to the NlpA lipoprotein family
H7R40_RS21410	COG1720	tRNA m6t6A37 methyltransferase activity
H7R40_RS21420	COG0791	NLP P60 protein
H7R40_RS21425	COG3015	lipoprotein NlpE involved in copper resistance
H7R40_RS21430	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H7R40_RS21445	COG4568	rho-dependent transcription termination
H7R40_RS21455	COG0346	lactoylglutathione lyase activity
H7R40_RS21460	COG1982	Orn Lys Arg decarboxylase major
H7R40_RS21470	COG0587	DNA-directed DNA polymerase activity
H7R40_RS21500	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
H7R40_RS21510	COG0750	zinc metalloprotease
H7R40_RS21515	COG0575	Belongs to the CDS family
H7R40_RS21525	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H7R40_RS21550	COG0024	Methionine aminopeptidase
H7R40_RS21555	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
H7R40_RS21570	COG3835	regulator
H7R40_RS21575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7R40_RS21595	COG2860	membrane
H7R40_RS21615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R40_RS21620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7R40_RS21625	COG1120	ATPase activity
H7R40_RS21630	COG4774	siderophore transport
H7R40_RS21635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7R40_RS21730	COG1643	Atp-dependent helicase
H7R40_RS21735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H7R40_RS21755	COG0617	tRNA 3'-terminal CCA addition
H7R40_RS21760	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H7R40_RS21780	COG0726	polysaccharide deacetylase
H7R40_RS21785	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R40_RS21790	COG0842	Transport permease protein
H7R40_RS21795	COG1131	(ABC) transporter
H7R40_RS21800	COG0288	reversible hydration of carbon dioxide
H7R40_RS21815	COG4993	Dehydrogenase
H7R40_RS21820	COG2132	Multicopper oxidase
H7R40_RS21865	COG3064	Membrane
H7R40_RS21880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7R40_RS21885	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7R40_RS21890	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H7R40_RS21895	COG2186	Transcriptional regulator
H7R40_RS21900	COG1113	amino acid transport
H7R40_RS21905	COG2211	Major facilitator Superfamily
H7R40_RS21910	COG3940	Belongs to the glycosyl hydrolase 43 family
H7R40_RS21915	COG3725	Membrane protein required for beta-lactamase induction
H7R40_RS21920	COG3023	N-Acetylmuramoyl-L-alanine amidase
H7R40_RS21930	COG4969	Belongs to the N-Me-Phe pilin family
H7R40_RS21935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7R40_RS21940	COG1459	type II secretion system
H7R40_RS21965	COG0494	nUDIX hydrolase
H7R40_RS21985	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H7R40_RS21990	COG0849	cell division
H7R40_RS22015	COG0772	Belongs to the SEDS family
H7R40_RS22030	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7R40_RS22035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7R40_RS22040	COG0768	penicillin binding
H7R40_RS22060	COG1609	Transcriptional regulator
H7R40_RS22070	COG0028	Belongs to the TPP enzyme family
H7R40_RS22115	COG0738	Major facilitator superfamily
H7R40_RS22125	COG0583	DNA-binding transcription factor activity
H7R40_RS22130	COG2271	Major facilitator Superfamily
H7R40_RS22135	COG2814	Major facilitator Superfamily
H7R40_RS22155	COG1178	ABC-type Fe3 transport system permease component
H7R40_RS22165	COG0586	Pfam SNARE associated Golgi protein
H7R40_RS22185	COG0235	Class ii aldolase
H7R40_RS22190	COG0417	DNA replication proofreading
H7R40_RS22200	COG0564	pseudouridine synthase activity
H7R40_RS22210	COG3493	citrate carrier protein
H7R40_RS22225	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H7R40_RS22230	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H7R40_RS22240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H7R40_RS22285	COG0505	Belongs to the CarA family
H7R40_RS22350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H7R40_RS22375	COG1047	Peptidyl-prolyl cis-trans
H7R40_RS22390	COG0196	riboflavin kinase activity
H7R40_RS22400	COG0583	DNA-binding transcription factor activity
H7R40_RS22425	COG4735	regulation of single-species biofilm formation
H7R40_RS22430	COG1584	GPR1 FUN34 yaaH family protein
H7R40_RS22435	COG0477	Major facilitator Superfamily
H7R40_RS22440	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7R40_RS22445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7R40_RS22450	COG1115	amino acid carrier protein
H7R40_RS22465	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7R40_RS22475	COG0527	aspartate kinase activity
H7R40_RS22475	COG0460	homoserine dehydrogenase
H7R40_RS22485	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
H7R40_RS22495	COG0745	RESPONSE REGULATOR receiver
H7R40_RS22500	COG4452	Inner membrane protein CreD
H7R40_RS22505	COG2205	protein histidine kinase activity
H7R40_RS22510	COG0745	RESPONSE REGULATOR receiver
H7R40_RS22515	COG3045	CreA protein
H7R40_RS22520	COG3708	Transcriptional regulator
H7R40_RS22520	COG2207	Transcriptional regulator
H7R40_RS22540	COG0741	lytic transglycosylase activity
H7R40_RS22545	COG0488	(ABC) transporter
H7R40_RS22555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H7R40_RS22560	COG0560	Phosphoserine phosphatase
H7R40_RS22565	COG3726	membrane protein affecting hemolysin expression
H7R40_RS22595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7R40_RS22600	COG0084	hydrolase, TatD family'
H7R40_RS22605	COG4667	esterase of the alpha-beta hydrolase superfamily
H7R40_RS22615	COG2823	Periplasmic or secreted lipoprotein
H7R40_RS22625	COG1011	Hydrolase
H7R40_RS22630	COG0456	acetyltransferase
H7R40_RS22635	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
H7R40_RS22665	COG3706	GGDEF domain
H7R40_RS22670	COG4114	ferric iron reductase
H7R40_RS22675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R40_RS22675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R40_RS22680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H7R40_RS22685	COG2197	response regulator
H7R40_RS22690	COG2197	response regulator
H7R40_RS22705	COG2966	Psort location CytoplasmicMembrane, score
H7R40_RS22720	COG1484	DNA-dependent DNA replication
H7R40_RS22735	COG5464	transposase or invertase
H7R40_RS22745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H7R40_RS22750	COG3716	PTS system mannose fructose sorbose family IID component
H7R40_RS22755	COG3715	PTS system
H7R40_RS22770	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H7R40_RS22770	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7R40_RS22775	COG0456	acetyltransferase
H7R40_RS22775	COG1214	PFAM Peptidase M22, glycoprotease
H7R40_RS22785	COG1737	Transcriptional regulator
H7R40_RS22790	COG0800	Aldolase
H7R40_RS22795	COG3734	2-keto-3-deoxy-galactonokinase
H7R40_RS22800	COG4145	pantothenate transmembrane transporter activity
H7R40_RS22810	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
H7R40_RS22830	COG0531	amino acid
H7R40_RS22835	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS22840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7R40_RS22855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7R40_RS22855	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H7R40_RS22870	COG1846	Transcriptional regulator
H7R40_RS22880	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7R40_RS22890	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS22895	COG3384	dioxygenase
H7R40_RS22905	COG3971	2-oxopent-4-enoate hydratase activity
H7R40_RS22925	COG2368	4-hydroxyphenylacetate
H7R40_RS22930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R40_RS22935	COG1966	Carbon starvation protein
H7R40_RS22940	COG2879	small protein
H7R40_RS22945	COG0523	cobalamin synthesis protein
H7R40_RS22955	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS22960	COG5464	transposase or invertase
H7R40_RS22965	COG1917	Cupin 2, conserved barrel domain protein
H7R40_RS22965	COG2207	Transcriptional regulator
H7R40_RS22975	COG2733	membrane
H7R40_RS22990	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
H7R40_RS22995	COG1924	4 iron, 4 sulfur cluster binding
H7R40_RS23010	COG1566	PFAM secretion protein HlyD family protein
H7R40_RS23020	COG5457	Domain of unknown function (DUF1127)
H7R40_RS23025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R40_RS23035	COG0583	DNA-binding transcription factor activity
H7R40_RS23075	COG1012	belongs to the aldehyde dehydrogenase family
H7R40_RS23075	COG1454	alcohol dehydrogenase
H7R40_RS23090	COG1882	Formate acetyltransferase
H7R40_RS23095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H7R40_RS23105	COG4869	propanediol catabolic process
H7R40_RS23130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R40_RS23135	COG0842	Transport permease protein
H7R40_RS23135	COG1129	ABC transporter
H7R40_RS23140	COG0842	Transport permease protein
H7R40_RS23170	COG2850	peptidyl-arginine hydroxylation
H7R40_RS23185	COG5002	protein histidine kinase activity
H7R40_RS23190	COG0745	RESPONSE REGULATOR receiver
H7R40_RS23195	COG1538	Outer membrane efflux protein
H7R40_RS23200	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R40_RS23205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R40_RS23210	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R40_RS23220	COG3040	lipid binding
H7R40_RS23225	COG0789	Transcriptional regulator
H7R40_RS23235	COG0300	oxidoreductase activity
H7R40_RS23250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7R40_RS23270	COG3272	Protein of unknown function (DUF1722)
H7R40_RS23275	COG4580	involved in the transport of maltose and maltodextrins
H7R40_RS23280	COG2115	Belongs to the xylose isomerase family
H7R40_RS23285	COG2211	Major facilitator Superfamily
H7R40_RS23290	COG3507	Belongs to the glycosyl hydrolase 43 family
H7R40_RS23330	COG0288	reversible hydration of carbon dioxide
H7R40_RS23335	COG0659	secondary active sulfate transmembrane transporter activity
H7R40_RS23340	COG1064	alcohol dehydrogenase
H7R40_RS23345	COG1175	transmembrane transport
H7R40_RS23350	COG0395	ABC-type sugar transport system, permease component
H7R40_RS23355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7R40_RS23360	COG3842	ATPase activity
H7R40_RS23375	COG1082	Xylose isomerase domain protein TIM barrel
H7R40_RS23385	COG3962	Belongs to the TPP enzyme family
H7R40_RS23390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R40_RS23395	COG0837	glucose binding
H7R40_RS23395	COG1737	Transcriptional regulator
H7R40_RS23400	COG3718	enzyme involved in inositol metabolism
H7R40_RS23415	COG0433	COG0433 Predicted ATPase
H7R40_RS23420	COG0795	lipopolysaccharide-transporting ATPase activity
H7R40_RS23425	COG0795	lipopolysaccharide-transporting ATPase activity
H7R40_RS23435	COG2927	DNA polymerase III (CHI subunit)
H7R40_RS23440	COG0525	valine-tRNA ligase activity
H7R40_RS23465	COG2188	Transcriptional regulator
H7R40_RS23470	COG1288	antiporter activity
H7R40_RS23475	COG1228	amidohydrolase
H7R40_RS23480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R40_RS23485	COG2222	sugar isomerase
H7R40_RS23490	COG2731	YhcH YjgK YiaL family protein
H7R40_RS23525	COG1263	PTS System
H7R40_RS23525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7R40_RS23530	COG0366	Alpha amylase catalytic
H7R40_RS23535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7R40_RS23540	COG1486	melibiose metabolic process
H7R40_RS23565	COG0602	queuosine metabolic process
H7R40_RS23570	COG2026	Addiction module toxin, RelE StbE family
H7R40_RS23580	COG3711	transcriptional antiterminator
H7R40_RS23580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R40_RS23585	COG2706	6-phosphogluconolactonase activity
H7R40_RS23600	COG3964	amidohydrolase
H7R40_RS23635	COG0312	modulator of DNA gyrase
H7R40_RS23655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7R40_RS23665	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS23670	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS23675	COG1129	ABC transporter
H7R40_RS23680	COG1879	ABC-type sugar transport system periplasmic component
H7R40_RS23705	COG2105	PFAM AIG2 family protein
H7R40_RS23710	COG2911	Protein conserved in bacteria
H7R40_RS23715	COG0729	surface antigen
H7R40_RS23725	COG1253	flavin adenine dinucleotide binding
H7R40_RS23750	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H7R40_RS23765	COG1733	regulation of RNA biosynthetic process
H7R40_RS23770	COG0702	epimerase
H7R40_RS23780	COG0697	spore germination
H7R40_RS23790	COG1113	amino acid transport
H7R40_RS23795	COG0545	Peptidyl-prolyl cis-trans isomerase
H7R40_RS23800	COG3061	Opacity-associated protein A
H7R40_RS23810	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H7R40_RS23815	COG2965	DNA replication, synthesis of RNA primer
H7R40_RS23875	COG1073	alpha beta
H7R40_RS23880	COG3650	response to hydrogen peroxide
H7R40_RS23890	COG1960	acyl-CoA dehydrogenase activity
H7R40_RS23895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7R40_RS23900	COG0557	exoribonuclease II activity
H7R40_RS23915	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H7R40_RS23925	COG0330	HflC and HflK could
H7R40_RS23930	COG0330	HflC and HflK could
H7R40_RS23935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7R40_RS23955	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7R40_RS23960	COG0802	atpase or kinase
H7R40_RS23965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H7R40_RS23965	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H7R40_RS23970	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H7R40_RS23990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R40_RS24010	COG3264	Mechanosensitive ion channel
H7R40_RS24010	COG1511	domain protein
H7R40_RS24025	COG1053	succinate dehydrogenase
H7R40_RS24030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7R40_RS24050	COG2076	Multidrug Resistance protein
H7R40_RS24055	COG5510	response to toxic substance
H7R40_RS24070	COG1509	lysine 2,3-aminomutase activity
H7R40_RS24075	COG0745	RESPONSE REGULATOR receiver
H7R40_RS24125	COG3539	Fimbrial protein
H7R40_RS24160	COG0531	amino acid
H7R40_RS24165	COG3030	protein affecting phage T7 exclusion by the F plasmid
H7R40_RS24170	COG1027	Aspartate ammonia-lyase
H7R40_RS24175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H7R40_RS24190	COG1309	transcriptional regulator
H7R40_RS24220	COG0457	Tetratricopeptide repeat
H7R40_RS24225	COG0726	polysaccharide deacetylase
H7R40_RS24225	COG1649	PFAM Uncharacterised BCR, COG1649
H7R40_RS24230	COG1215	transferase activity, transferring glycosyl groups
H7R40_RS24245	COG0861	Integral membrane protein TerC family
H7R40_RS24285	COG1486	melibiose metabolic process
H7R40_RS24290	COG2169	Transcriptional regulator
H7R40_RS24300	COG2824	Alkylphosphonate utilization operon protein PhnA
H7R40_RS24305	COG2764	glyoxalase bleomycin resistance protein dioxygenase
H7R40_RS24310	COG2188	Transcriptional regulator
H7R40_RS24315	COG3624	Phosphonate C-P lyase system protein PhnG
H7R40_RS24320	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
H7R40_RS24325	COG3626	phosphonate metabolism
H7R40_RS24330	COG3627	carbon phosphorus lyase activity
H7R40_RS24335	COG4107	phosphonate C-P lyase system protein PhnK
H7R40_RS24340	COG4778	phosphonate C-P lyase system protein PhnL
H7R40_RS24345	COG3454	Phosphonate metabolism
H7R40_RS24355	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H7R40_RS24365	COG4191	Histidine kinase
H7R40_RS24365	COG0784	Response regulator, receiver
H7R40_RS24370	COG1129	ABC transporter
H7R40_RS24375	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS24410	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H7R40_RS24415	COG1301	dicarboxylic acid transport
H7R40_RS24425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7R40_RS24430	COG3162	membrane
H7R40_RS24465	COG1346	cytolysis
H7R40_RS24470	COG1380	Effector of murein hydrolase LrgA
H7R40_RS24475	COG0583	DNA-binding transcription factor activity
H7R40_RS24480	COG0025	NhaP-type Na H and K H
H7R40_RS24485	COG2252	PERMEase
H7R40_RS24490	COG0625	glutathione transferase activity
H7R40_RS24495	COG0789	Transcriptional regulator
H7R40_RS24505	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H7R40_RS24535	COG1234	tRNA 3'-trailer cleavage
H7R40_RS24540	COG1609	Transcriptional regulator
H7R40_RS24545	COG0483	inositol monophosphate 1-phosphatase activity
H7R40_RS24555	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7R40_RS24575	COG4771	TonB-dependent receptor
H7R40_RS24580	COG0741	lytic transglycosylase activity
H7R40_RS24595	COG2315	Protein conserved in bacteria
H7R40_RS24600	COG0432	Pfam Uncharacterised protein family UPF0047
H7R40_RS24615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7R40_RS24620	COG0305	Participates in initiation and elongation during chromosome replication
H7R40_RS24635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7R40_RS24645	COG0735	belongs to the Fur family
H7R40_RS24650	COG3237	CsbD-like
H7R40_RS24660	COG0534	Mate efflux family protein
H7R40_RS24670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H7R40_RS24740	COG0251	oxidation-reduction process
H7R40_RS24750	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7R40_RS24760	COG0527	aspartate kinase activity
H7R40_RS24815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7R40_RS24845	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H7R40_RS24855	COG0456	acetyltransferase
H7R40_RS24885	COG0151	Belongs to the GarS family
H7R40_RS24895	COG4191	Histidine kinase
H7R40_RS24900	COG3678	ATP-independent chaperone mediated protein folding
H7R40_RS24935	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
H7R40_RS24950	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7R40_RS24955	COG2104	thiamine diphosphate biosynthetic process
H7R40_RS24970	COG3706	GGDEF domain
H7R40_RS24980	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7R40_RS24985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H7R40_RS25020	COG0250	Participates in transcription elongation, termination and antitermination
H7R40_RS25095	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
H7R40_RS25105	COG1739	Uncharacterized protein family UPF0029
H7R40_RS25145	COG0805	protein transport
H7R40_RS25165	COG3165	ubiquinone biosynthetic process from chorismate
H7R40_RS25195	COG0583	DNA-binding transcription factor activity
H7R40_RS25200	COG0697	spore germination
H7R40_RS25205	COG0561	phosphatase activity
H7R40_RS25210	COG2267	carboxylic ester hydrolase activity
H7R40_RS25215	COG1280	lysine exporter protein (LysE YggA)
H7R40_RS25225	COG1280	lysine exporter protein (LysE YggA)
H7R40_RS25255	COG0210	DNA helicase
H7R40_RS25260	COG1011	Hydrolase
H7R40_RS25290	COG3072	Adenylate cyclase
H7R40_RS25305	COG2959	enzyme of heme biosynthesis
H7R40_RS25310	COG3071	HemY protein
H7R40_RS25355	COG2244	polysaccharide biosynthetic process
H7R40_RS25360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7R40_RS25365	COG0456	acetyltransferase
H7R40_RS25370	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H7R40_RS25375	COG1088	dTDP-glucose 4,6-dehydratase activity
H7R40_RS25380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H7R40_RS25385	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H7R40_RS25395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7R40_RS25400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H7R40_RS25405	COG3118	belongs to the thioredoxin family
H7R40_RS25430	COG1811	Na channel or pump
H7R40_RS25440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7R40_RS25445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7R40_RS25455	COG0583	DNA-binding transcription factor activity
H7R40_RS25460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7R40_RS25475	COG3978	acetolactate synthase activity
H7R40_RS25495	COG3085	chromosome segregation
H7R40_RS25570	COG0583	DNA-binding transcription factor activity
H7R40_RS25585	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H7R40_RS25600	COG3443	Belongs to the bacterial solute-binding protein 9 family
H7R40_RS25605	COG2207	Transcriptional regulator
H7R40_RS25615	COG0371	Dehydrogenase
H7R40_RS25620	COG0697	spore germination
H7R40_RS25630	COG0583	DNA-binding transcription factor activity
H7R40_RS25640	COG0737	Belongs to the 5'-nucleotidase family
H7R40_RS25650	COG0460	homoserine dehydrogenase
H7R40_RS25650	COG0527	aspartate kinase activity
H7R40_RS25655	COG0626	cystathionine gamma-synthase activity
H7R40_RS25670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7R40_RS25675	COG1609	Transcriptional regulator
H7R40_RS25680	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7R40_RS25695	COG1575	Belongs to the MenA family. Type 1 subfamily
H7R40_RS25715	COG3678	ATP-independent chaperone mediated protein folding
H7R40_RS25720	COG0745	RESPONSE REGULATOR receiver
H7R40_RS25725	COG2205	protein histidine kinase activity
H7R40_RS25730	COG2258	MOSC domain
H7R40_RS25735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7R40_RS25775	COG1129	ABC transporter
H7R40_RS25780	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS25785	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS25790	COG1454	alcohol dehydrogenase
H7R40_RS25800	COG2211	Major facilitator Superfamily
H7R40_RS25845	COG0437	4 iron, 4 sulfur cluster binding
H7R40_RS25850	COG2864	formate dehydrogenase
H7R40_RS25865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7R40_RS25875	COG0456	acetyltransferase
H7R40_RS25890	COG1011	Hydrolase
H7R40_RS25905	COG3852	Histidine kinase
H7R40_RS25920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7R40_RS25940	COG0204	Acyl-transferase
H7R40_RS25950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7R40_RS25955	COG3084	Protein conserved in bacteria
H7R40_RS25965	COG1763	Mo-molybdopterin cofactor biosynthetic process
H7R40_RS25990	COG2186	Transcriptional regulator
H7R40_RS25995	COG0477	Major facilitator Superfamily
H7R40_RS26000	COG1609	Transcriptional regulator
H7R40_RS26005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R40_RS26015	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7R40_RS26020	COG1129	ABC transporter
H7R40_RS26050	COG1522	sequence-specific DNA binding
H7R40_RS26055	COG0716	FMN binding
H7R40_RS26070	COG3312	ion transport
H7R40_RS26120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H7R40_RS26125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H7R40_RS26130	COG0573	inorganic phosphate transmembrane transporter activity
H7R40_RS26135	COG0581	inorganic phosphate transmembrane transporter activity
H7R40_RS26140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7R40_RS26145	COG0704	Plays a role in the regulation of phosphate uptake
H7R40_RS26155	COG2382	esterase
H7R40_RS26160	COG0363	glucosamine-6-phosphate deaminase activity
H7R40_RS26165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R40_RS26170	COG2252	PERMEase
H7R40_RS26175	COG0431	NADPH-dependent FMN reductase
H7R40_RS26180	COG2091	lysine biosynthetic process via aminoadipic acid
H7R40_RS26210	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7R40_RS26260	COG4172	Belongs to the ABC transporter superfamily
H7R40_RS26280	COG2223	nitrite transmembrane transporter activity
H7R40_RS26290	COG1609	Transcriptional regulator
H7R40_RS26310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7R40_RS26315	COG0501	Belongs to the peptidase M48B family
H7R40_RS26370	COG0542	response to heat
H7R40_RS26375	COG0071	Belongs to the small heat shock protein (HSP20) family
H7R40_RS26425	COG0058	SHG alpha-glucan phosphorylase activity
H7R40_RS26430	COG0033	Phosphoglucomutase
H7R40_RS26460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7R40_RS26525	COG2801	Transposase and inactivated derivatives
H7R40_RS26535	COG2801	Transposase and inactivated derivatives
H7R40_RS26600	COG2205	protein histidine kinase activity
H7R40_RS26605	COG0745	RESPONSE REGULATOR receiver
H7R40_RS26610	COG1276	copper resistance
H7R40_RS26615	COG2372	response to copper ion
H7R40_RS26620	COG3667	copper resistance
H7R40_RS26625	COG2132	Multicopper oxidase
H7R40_RS26635	COG0739	heme binding
H7R40_RS26665	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R40_RS26815	COG3039	Transposase
H7R40_RS26890	COG3344	reverse transcriptase
H7R40_RS26985	COG1475	DNA binding
H7R40_RS27055	COG5499	transcription regulator containing HTH domain
H7R40_RS27285	COG3012	SEC-C Motif Domain Protein
H7R40_RS27285	COG3318	Belongs to the UPF0149 family
H7R40_RS27290	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H7R40_RS27495	COG1192	Involved in chromosome partitioning
H7R40_RS27575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7R40_RS27670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7R40_RS27695	COG5001	Diguanylate cyclase
H7R40_RS27735	COG0714	Associated with various cellular activities
H7R40_RS27745	COG0629	single-stranded DNA binding
H7R40_RS27790	COG0633	Ferredoxin
H7R40_RS27940	COG3300	MHYT domain
H7R40_RS27940	COG5001	Diguanylate cyclase
H7R40_RS27995	COG1983	PspC domain protein
H7R40_RS28005	COG1842	Phage shock protein A
H7R40_RS28010	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7R40_RS28020	COG1028	Short-chain dehydrogenase reductase Sdr
H7R40_RS28025	COG1546	Belongs to the CinA family
H7R40_RS28145	COG4974	Belongs to the 'phage' integrase family
H7R40_RS28285	COG0616	signal peptide processing
H7R40_RS28390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7R40_RS28455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7R40_RS28550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7R40_RS28600	COG4644	lycopene metabolic process
H7R40_RS28870	COG1192	Involved in chromosome partitioning
H7R40_RS29010	COG2916	Histone family protein nucleoid-structuring protein H-NS
H7R40_RS29055	COG2944	sequence-specific DNA binding