locus-tag	class	description
I5Q76_RS00020	COG0187	DNA topoisomerase II activity
I5Q76_RS00025	COG0561	phosphatase activity
I5Q76_RS00040	COG2186	Transcriptional regulator
I5Q76_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
I5Q76_RS00050	COG0800	Aldolase
I5Q76_RS00060	COG2271	Major facilitator Superfamily
I5Q76_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
I5Q76_RS00070	COG5645	(Lipo)protein
I5Q76_RS00085	COG3645	SOS response
I5Q76_RS00095	COG2188	Transcriptional regulator
I5Q76_RS00110	COG2149	membrane
I5Q76_RS00130	COG2610	gluconate transmembrane transporter activity
I5Q76_RS00140	COG0583	DNA-binding transcription factor activity
I5Q76_RS00145	COG2814	Major facilitator Superfamily
I5Q76_RS00175	COG0028	Belongs to the TPP enzyme family
I5Q76_RS00180	COG0440	acetolactate synthase activity
I5Q76_RS00185	COG2197	response regulator
I5Q76_RS00195	COG2271	Major facilitator Superfamily
I5Q76_RS00235	COG2188	Transcriptional regulator
I5Q76_RS00260	COG4580	involved in the transport of maltose and maltodextrins
I5Q76_RS00265	COG1447	Phosphotransferase system cellobiose-specific component IIA
I5Q76_RS00270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5Q76_RS00270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5Q76_RS00280	COG1609	Transcriptional regulator
I5Q76_RS00290	COG3384	dioxygenase
I5Q76_RS00295	COG0583	DNA-binding transcription factor activity
I5Q76_RS00300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I5Q76_RS00305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
I5Q76_RS00310	COG2828	Protein conserved in bacteria
I5Q76_RS00325	COG0697	spore germination
I5Q76_RS00330	COG1263	PTS System
I5Q76_RS00330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5Q76_RS00340	COG2814	Major facilitator Superfamily
I5Q76_RS00350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5Q76_RS00385	COG0583	DNA-binding transcription factor activity
I5Q76_RS00410	COG1464	Belongs to the NlpA lipoprotein family
I5Q76_RS00425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
I5Q76_RS00435	COG1064	alcohol dehydrogenase
I5Q76_RS00465	COG2211	Major facilitator Superfamily
I5Q76_RS00470	COG1501	Belongs to the glycosyl hydrolase 31 family
I5Q76_RS00480	COG1486	melibiose metabolic process
I5Q76_RS00485	COG1263	PTS System
I5Q76_RS00485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5Q76_RS00490	COG2982	Protein involved in outer membrane biogenesis
I5Q76_RS00495	COG2233	PERMEase
I5Q76_RS00500	COG0786	glutamate:sodium symporter activity
I5Q76_RS00520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
I5Q76_RS00545	COG3152	Membrane
I5Q76_RS00555	COG1494	fructose-1,6-bisphosphatase
I5Q76_RS00560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
I5Q76_RS00565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I5Q76_RS00570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I5Q76_RS00590	COG2860	membrane
I5Q76_RS00600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I5Q76_RS00600	COG2169	Transcriptional regulator
I5Q76_RS00605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
I5Q76_RS00610	COG1561	YicC-like family, N-terminal region
I5Q76_RS00630	COG1131	(ABC) transporter
I5Q76_RS00635	COG0842	Transport permease protein
I5Q76_RS00660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I5Q76_RS00695	COG1519	Transferase
I5Q76_RS00700	COG1216	Glycosyl transferase, family 2
I5Q76_RS00705	COG0438	transferase activity, transferring glycosyl groups
I5Q76_RS00715	COG0859	PFAM glycosyl transferase family 9
I5Q76_RS00740	COG0859	PFAM glycosyl transferase family 9
I5Q76_RS00755	COG0156	8-amino-7-oxononanoate synthase activity
I5Q76_RS00765	COG0463	Glycosyl transferase, family 2
I5Q76_RS00770	COG2861	carbohydrate metabolic process
I5Q76_RS00775	COG4942	peptidase
I5Q76_RS00785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I5Q76_RS00790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
I5Q76_RS00810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
I5Q76_RS00820	COG2186	Transcriptional regulator
I5Q76_RS00840	COG3722	fumarate hydratase activity
I5Q76_RS00860	COG1566	PFAM secretion protein HlyD family protein
I5Q76_RS00865	COG0625	glutathione transferase activity
I5Q76_RS00875	COG3276	selenocysteine insertion sequence binding
I5Q76_RS00880	COG1414	Transcriptional regulator
I5Q76_RS00885	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
I5Q76_RS00890	COG3977	Valine--pyruvate aminotransferase
I5Q76_RS00895	COG0366	Alpha amylase catalytic
I5Q76_RS00900	COG2992	FlgJ-related protein
I5Q76_RS00905	COG1609	Transcriptional regulator
I5Q76_RS00905	COG2207	Transcriptional regulator
I5Q76_RS00910	COG4214	carbohydrate transport
I5Q76_RS00920	COG4213	ABC transporter substrate-binding protein
I5Q76_RS00935	COG4682	membrane
I5Q76_RS00940	COG4682	membrane
I5Q76_RS00945	COG3274	enterobacterial common antigen metabolic process
I5Q76_RS00975	COG1278	Cold shock
I5Q76_RS00980	COG2944	sequence-specific DNA binding
I5Q76_RS00985	COG2814	Major facilitator Superfamily
I5Q76_RS01005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5Q76_RS01015	COG1609	Transcriptional regulator
I5Q76_RS01020	COG2885	chlorophyll binding
I5Q76_RS01025	COG0243	molybdopterin cofactor binding
I5Q76_RS01030	COG0456	acetyltransferase
I5Q76_RS01035	COG2818	Glycosylase
I5Q76_RS01040	COG5571	outer membrane autotransporter
I5Q76_RS01045	COG2223	nitrite transmembrane transporter activity
I5Q76_RS01065	COG0747	negative chemotaxis
I5Q76_RS01070	COG0601	transmembrane transport
I5Q76_RS01075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I5Q76_RS01080	COG0444	Belongs to the ABC transporter superfamily
I5Q76_RS01085	COG4608	Belongs to the ABC transporter superfamily
I5Q76_RS01100	COG2894	cell division
I5Q76_RS01110	COG1215	transferase activity, transferring glycosyl groups
I5Q76_RS01115	COG0457	Tetratricopeptide repeat
I5Q76_RS01130	COG2194	sulfuric ester hydrolase activity
I5Q76_RS01160	COG1215	transferase activity, transferring glycosyl groups
I5Q76_RS01165	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
I5Q76_RS01170	COG3118	belongs to the thioredoxin family
I5Q76_RS01170	COG0457	Tetratricopeptide repeat
I5Q76_RS01175	COG2199	diguanylate cyclase activity
I5Q76_RS01175	COG2200	EAL domain
I5Q76_RS01185	COG0612	Peptidase, M16
I5Q76_RS01195	COG2982	Protein involved in outer membrane biogenesis
I5Q76_RS01200	COG0477	Major facilitator Superfamily
I5Q76_RS01205	COG1295	ribonuclease BN
I5Q76_RS01210	COG0583	DNA-binding transcription factor activity
I5Q76_RS01215	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS01220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I5Q76_RS01230	COG1454	alcohol dehydrogenase
I5Q76_RS01240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I5Q76_RS01245	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
I5Q76_RS01250	COG0671	phosphoesterase, PA-phosphatase related
I5Q76_RS01270	COG0589	response to stress
I5Q76_RS01280	COG0306	phosphate transporter
I5Q76_RS01285	COG2081	HI0933 family
I5Q76_RS01310	COG1124	(ABC) transporter
I5Q76_RS01320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I5Q76_RS01325	COG0601	transmembrane transport
I5Q76_RS01340	COG3479	Phenolic acid decarboxylase
I5Q76_RS01380	COG0628	permease
I5Q76_RS01385	COG0477	Major facilitator Superfamily
I5Q76_RS01395	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
I5Q76_RS01410	COG3714	YhhN family
I5Q76_RS01420	COG3776	membrane
I5Q76_RS01425	COG0742	ribosomal rna small subunit methyltransferase
I5Q76_RS01430	COG0552	protein localization to endoplasmic reticulum
I5Q76_RS01435	COG2884	Cell division ATP-binding protein ftsE
I5Q76_RS01440	COG2177	Part of the ABC transporter FtsEX involved in
I5Q76_RS01455	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
I5Q76_RS01465	COG0683	leucine binding
I5Q76_RS01475	COG0683	leucine binding
I5Q76_RS01480	COG0559	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS01530	COG0584	glycerophosphoryl diester phosphodiesterase
I5Q76_RS01540	COG0405	Gamma-glutamyltransferase
I5Q76_RS01545	COG1247	-acetyltransferase
I5Q76_RS01555	COG0673	inositol 2-dehydrogenase activity
I5Q76_RS01560	COG1741	Belongs to the pirin family
I5Q76_RS01565	COG1609	Transcriptional regulator
I5Q76_RS01570	COG3265	gluconokinase activity
I5Q76_RS01575	COG2610	gluconate transmembrane transporter activity
I5Q76_RS01585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I5Q76_RS01610	COG0058	SHG alpha-glucan phosphorylase activity
I5Q76_RS01615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I5Q76_RS01630	COG1349	DNA-binding transcription factor activity
I5Q76_RS01640	COG0058	SHG alpha-glucan phosphorylase activity
I5Q76_RS01645	COG1640	4-alpha-glucanotransferase
I5Q76_RS01650	COG2610	gluconate transmembrane transporter activity
I5Q76_RS01660	COG1040	competence protein
I5Q76_RS01685	COG1918	ferrous iron import across plasma membrane
I5Q76_RS01690	COG2183	response to ionizing radiation
I5Q76_RS01695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
I5Q76_RS01720	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
I5Q76_RS01725	COG1011	Hydrolase
I5Q76_RS01735	COG0494	nUDIX hydrolase
I5Q76_RS01740	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
I5Q76_RS01765	COG4796	Type ii and iii secretion system protein
I5Q76_RS01780	COG3266	domain, Protein
I5Q76_RS01785	COG0338	D12 class N6 adenine-specific DNA methyltransferase
I5Q76_RS01790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I5Q76_RS01815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I5Q76_RS01820	COG0402	S-adenosylhomocysteine deaminase activity
I5Q76_RS01825	COG0738	Major facilitator superfamily
I5Q76_RS01850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
I5Q76_RS01855	COG1289	transmembrane transporter activity
I5Q76_RS01865	COG1765	OsmC-like protein
I5Q76_RS01870	COG3954	Phosphoribulokinase
I5Q76_RS01880	COG0429	hydrolase of the alpha beta-hydrolase fold
I5Q76_RS01885	COG0488	(ABC) transporter
I5Q76_RS01900	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
I5Q76_RS01905	COG1047	Peptidyl-prolyl cis-trans
I5Q76_RS01915	COG0545	Peptidyl-prolyl cis-trans isomerase
I5Q76_RS01920	COG2964	Protein conserved in bacteria
I5Q76_RS01975	COG0051	transcription antitermination factor activity, RNA binding
I5Q76_RS02000	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
I5Q76_RS02015	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
I5Q76_RS02080	COG0201	protein transport
I5Q76_RS02105	COG0202	RNA polymerase activity
I5Q76_RS02120	COG0789	Transcriptional regulator
I5Q76_RS02125	COG3036	rescue of stalled ribosome
I5Q76_RS02155	COG0758	DNA mediated transformation
I5Q76_RS02165	COG0551	DNA topoisomerase type I activity
I5Q76_RS02185	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I5Q76_RS02220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5Q76_RS02225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5Q76_RS02230	COG1309	transcriptional regulator
I5Q76_RS02250	COG4145	pantothenate transmembrane transporter activity
I5Q76_RS02255	COG3924	membrane
I5Q76_RS02260	COG0439	Biotin carboxylase
I5Q76_RS02265	COG0511	ligase activity, forming carbon-carbon bonds
I5Q76_RS02290	COG2200	EAL domain
I5Q76_RS02290	COG2199	diguanylate cyclase activity
I5Q76_RS02295	COG1077	Cell shape determining protein MreB Mrl
I5Q76_RS02300	COG1792	Involved in formation and maintenance of cell shape
I5Q76_RS02305	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
I5Q76_RS02315	COG1530	ribonuclease E activity
I5Q76_RS02320	COG3164	Protein of unknown function
I5Q76_RS02325	COG0312	modulator of DNA gyrase
I5Q76_RS02330	COG0583	DNA-binding transcription factor activity
I5Q76_RS02345	COG1289	transmembrane transporter activity
I5Q76_RS02350	COG2732	(Barnase) inhibitor
I5Q76_RS02375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I5Q76_RS02380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I5Q76_RS02385	COG3105	Protein conserved in bacteria
I5Q76_RS02390	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
I5Q76_RS02405	COG0625	glutathione transferase activity
I5Q76_RS02410	COG2969	positive regulation of protein catabolic process
I5Q76_RS02420	COG0493	'glutamate synthase
I5Q76_RS02425	COG0069	glutamate synthase activity
I5Q76_RS02425	COG0070	glutamate synthase
I5Q76_RS02425	COG0067	glutamate synthase
I5Q76_RS02430	COG1242	4 iron, 4 sulfur cluster binding
I5Q76_RS02435	COG2271	Major facilitator Superfamily
I5Q76_RS02440	COG1063	alcohol dehydrogenase
I5Q76_RS02445	COG1312	Catalyzes the dehydration of D-mannonate
I5Q76_RS02450	COG2198	Histidine kinase
I5Q76_RS02450	COG0784	Response regulator, receiver
I5Q76_RS02450	COG5002	protein histidine kinase activity
I5Q76_RS02455	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
I5Q76_RS02460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I5Q76_RS02465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS02475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS02480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
I5Q76_RS02485	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
I5Q76_RS02490	COG1137	ATPase activity
I5Q76_RS02495	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
I5Q76_RS02500	COG3117	lipopolysaccharide transmembrane transporter activity
I5Q76_RS02505	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
I5Q76_RS02515	COG0530	calcium, potassium:sodium antiporter activity
I5Q76_RS02520	COG1127	ABC transporter
I5Q76_RS02525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
I5Q76_RS02530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
I5Q76_RS02535	COG2854	intermembrane phospholipid transfer
I5Q76_RS02540	COG3113	response to antibiotic
I5Q76_RS02545	COG5007	Belongs to the BolA IbaG family
I5Q76_RS02555	COG3423	Transcriptional regulator
I5Q76_RS02560	COG0142	geranyltranstransferase activity
I5Q76_RS02575	COG0697	spore germination
I5Q76_RS02585	COG2027	D-alanyl-D-alanine carboxypeptidase
I5Q76_RS02595	COG1534	Rna-binding protein
I5Q76_RS02605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
I5Q76_RS02610	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
I5Q76_RS02620	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I5Q76_RS02660	COG0195	Participates in both transcription termination and antitermination
I5Q76_RS02705	COG0814	amino acid
I5Q76_RS02710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5Q76_RS02715	COG0826	peptidase U32
I5Q76_RS02720	COG0826	peptidase U32
I5Q76_RS02725	COG3154	lipid carrier protein
I5Q76_RS02730	COG3153	acetyltransferase
I5Q76_RS02745	COG0693	protein deglycase activity
I5Q76_RS02750	COG0702	epimerase
I5Q76_RS02755	COG0701	Predicted permease
I5Q76_RS02760	COG2823	Periplasmic or secreted lipoprotein
I5Q76_RS02780	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
I5Q76_RS02795	COG1063	alcohol dehydrogenase
I5Q76_RS02800	COG3775	system Galactitol-specific IIC component
I5Q76_RS02805	COG3414	Phosphotransferase system galactitol-specific IIB component
I5Q76_RS02810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS02820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS02820	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS02825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS02825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5Q76_RS02825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5Q76_RS02830	COG1105	Belongs to the carbohydrate kinase PfkB family
I5Q76_RS02840	COG1349	DNA-binding transcription factor activity
I5Q76_RS02845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5Q76_RS02850	COG2721	sulfolactate sulfo-lyase activity
I5Q76_RS02855	COG2271	Major facilitator Superfamily
I5Q76_RS02865	COG2084	Dehydrogenase
I5Q76_RS02870	COG1929	Belongs to the glycerate kinase type-1 family
I5Q76_RS02900	COG0583	DNA-binding transcription factor activity
I5Q76_RS02905	COG3152	Membrane
I5Q76_RS02910	COG0435	Glutathione S-transferase
I5Q76_RS02915	COG2259	Doxx family
I5Q76_RS02925	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
I5Q76_RS02930	COG4575	ribosome binding
I5Q76_RS02935	COG1422	Protein of unknown function (DUF1090)
I5Q76_RS02945	COG0586	Pfam SNARE associated Golgi protein
I5Q76_RS02965	COG2721	sulfolactate sulfo-lyase activity
I5Q76_RS02980	COG0861	Integral membrane protein TerC family
I5Q76_RS02985	COG0673	inositol 2-dehydrogenase activity
I5Q76_RS03010	COG1902	pentaerythritol trinitrate reductase activity
I5Q76_RS03010	COG0446	pyridine nucleotide-disulphide oxidoreductase
I5Q76_RS03060	COG1695	Transcriptional regulator
I5Q76_RS03065	COG2375	cellular response to nickel ion
I5Q76_RS03080	COG1461	Dihydroxyacetone kinase
I5Q76_RS03085	COG2376	Dihydroxyacetone kinase
I5Q76_RS03155	COG3247	response to pH
I5Q76_RS03165	COG2205	protein histidine kinase activity
I5Q76_RS03165	COG2198	Histidine kinase
I5Q76_RS03165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5Q76_RS03165	COG0784	Response regulator, receiver
I5Q76_RS03170	COG2197	response regulator
I5Q76_RS03195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
I5Q76_RS03200	COG0358	DNA primase activity
I5Q76_RS03205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
I5Q76_RS03270	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
I5Q76_RS03285	COG4991	sh3 domain protein
I5Q76_RS03290	COG3025	triphosphatase activity
I5Q76_RS03315	COG2960	long-chain fatty acid transporting porin activity
I5Q76_RS03330	COG3384	dioxygenase
I5Q76_RS03335	COG0754	glutathionylspermidine amidase activity
I5Q76_RS03350	COG0494	nUDIX hydrolase
I5Q76_RS03355	COG3151	Protein conserved in bacteria
I5Q76_RS03360	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
I5Q76_RS03365	COG3150	esterase
I5Q76_RS03375	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
I5Q76_RS03380	COG2249	NAD(P)H dehydrogenase (quinone) activity
I5Q76_RS03385	COG0642	Histidine kinase
I5Q76_RS03395	COG3111	PFAM Bacterial OB fold (BOF) protein
I5Q76_RS03400	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
I5Q76_RS03405	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
I5Q76_RS03410	COG0204	Acyl-transferase
I5Q76_RS03415	COG2132	Multicopper oxidase
I5Q76_RS03420	COG1032	radical SAM domain protein
I5Q76_RS03430	COG0656	L-ascorbic acid biosynthetic process
I5Q76_RS03435	COG1979	alcohol dehydrogenase
I5Q76_RS03440	COG2207	Transcriptional regulator
I5Q76_RS03445	COG0586	Pfam SNARE associated Golgi protein
I5Q76_RS03450	COG0626	cystathionine gamma-synthase activity
I5Q76_RS03460	COG0848	biopolymer transport protein
I5Q76_RS03465	COG2211	Major facilitator Superfamily
I5Q76_RS03490	COG0625	glutathione transferase activity
I5Q76_RS03505	COG0754	glutathionylspermidine amidase activity
I5Q76_RS03510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5Q76_RS03530	COG0583	DNA-binding transcription factor activity
I5Q76_RS03535	COG0626	cystathionine gamma-synthase activity
I5Q76_RS03550	COG1811	Na channel or pump
I5Q76_RS03555	COG1982	Orn Lys Arg decarboxylase major
I5Q76_RS03560	COG2211	Major facilitator Superfamily
I5Q76_RS03575	COG1194	a g-specific adenine glycosylase
I5Q76_RS03585	COG3171	Protein conserved in bacteria
I5Q76_RS03600	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
I5Q76_RS03600	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
I5Q76_RS03605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
I5Q76_RS03610	COG3039	Transposase
I5Q76_RS03615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I5Q76_RS03630	COG0762	integral membrane protein
I5Q76_RS03635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
I5Q76_RS03640	COG2805	Type II/IV secretion system protein
I5Q76_RS03665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
I5Q76_RS03670	COG2356	endonuclease I
I5Q76_RS03680	COG2814	Major facilitator Superfamily
I5Q76_RS03715	COG2146	nitrite reductase [NAD(P)H] activity
I5Q76_RS03730	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS03735	COG1414	Transcriptional regulator
I5Q76_RS03765	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS03770	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
I5Q76_RS03790	COG0501	Belongs to the peptidase M48B family
I5Q76_RS03795	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
I5Q76_RS03810	COG0191	fructose-bisphosphate aldolase activity
I5Q76_RS03815	COG0668	transmembrane transport
I5Q76_RS03825	COG2968	Membrane
I5Q76_RS03840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I5Q76_RS03845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
I5Q76_RS03865	COG0006	proline dipeptidase activity
I5Q76_RS03870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I5Q76_RS03875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I5Q76_RS03895	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS03905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I5Q76_RS03925	COG2723	6-phospho-beta-galactosidase activity
I5Q76_RS03930	COG1737	Transcriptional regulator
I5Q76_RS03940	COG1272	protein, Hemolysin III
I5Q76_RS03950	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
I5Q76_RS03960	COG0716	FMN binding
I5Q76_RS03965	COG4974	Belongs to the 'phage' integrase family
I5Q76_RS03975	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
I5Q76_RS03995	COG4942	peptidase
I5Q76_RS04005	COG2814	Major facilitator Superfamily
I5Q76_RS04020	COG0667	Aldo Keto reductase
I5Q76_RS04060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I5Q76_RS04065	COG1393	Belongs to the ArsC family
I5Q76_RS04080	COG1538	Outer membrane efflux protein
I5Q76_RS04085	COG1289	transmembrane transporter activity
I5Q76_RS04100	COG3592	Divergent 4Fe-4S mono-cluster
I5Q76_RS04105	COG2388	GCN5-related N-acetyl-transferase
I5Q76_RS04115	COG3539	Fimbrial protein
I5Q76_RS04120	COG3539	Fimbrial protein
I5Q76_RS04125	COG3539	Fimbrial protein
I5Q76_RS04130	COG3188	usher protein
I5Q76_RS04135	COG3121	Chaperone
I5Q76_RS04140	COG3539	Fimbrial protein
I5Q76_RS04150	COG4974	Belongs to the 'phage' integrase family
I5Q76_RS04155	COG0582	viral genome integration into host DNA
I5Q76_RS04160	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
I5Q76_RS04165	COG1846	Transcriptional regulator
I5Q76_RS04170	COG0697	spore germination
I5Q76_RS04220	COG0667	Aldo Keto reductase
I5Q76_RS04225	COG0814	amino acid
I5Q76_RS04240	COG0183	Belongs to the thiolase family
I5Q76_RS04250	COG0823	Involved in the tonB-independent uptake of proteins
I5Q76_RS04255	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS04260	COG2814	Major facilitator Superfamily
I5Q76_RS04295	COG3842	ATPase activity
I5Q76_RS04300	COG0395	ABC-type sugar transport system, permease component
I5Q76_RS04305	COG1175	transmembrane transport
I5Q76_RS04310	COG1917	Cupin 2, conserved barrel domain protein
I5Q76_RS04315	COG1794	racemase activity, acting on amino acids and derivatives
I5Q76_RS04320	COG0583	DNA-binding transcription factor activity
I5Q76_RS04330	COG1609	Transcriptional regulator
I5Q76_RS04335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5Q76_RS04340	COG2723	6-phospho-beta-galactosidase activity
I5Q76_RS04345	COG2186	Transcriptional regulator
I5Q76_RS04355	COG1609	Transcriptional regulator
I5Q76_RS04375	COG0667	Aldo Keto reductase
I5Q76_RS04385	COG0861	Integral membrane protein TerC family
I5Q76_RS04420	COG2165	general secretion pathway protein
I5Q76_RS04425	COG4795	General secretion pathway protein
I5Q76_RS04435	COG4967	type IV pilus modification protein PilV
I5Q76_RS04440	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
I5Q76_RS04445	COG1025	Belongs to the peptidase M16 family
I5Q76_RS04450	COG1074	ATP-dependent DNA helicase activity
I5Q76_RS04455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
I5Q76_RS04465	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
I5Q76_RS04465	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
I5Q76_RS04470	COG0860	N-Acetylmuramoyl-L-alanine amidase
I5Q76_RS04475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
I5Q76_RS04505	COG4656	Part of a membrane complex involved in electron transport
I5Q76_RS04510	COG1454	alcohol dehydrogenase
I5Q76_RS04510	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS04540	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
I5Q76_RS04765	COG2885	chlorophyll binding
I5Q76_RS04795	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
I5Q76_RS04800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
I5Q76_RS04805	COG2166	iron-sulfur cluster assembly
I5Q76_RS04810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
I5Q76_RS04820	COG0583	DNA-binding transcription factor activity
I5Q76_RS04825	COG2363	Small membrane protein
I5Q76_RS04835	COG1349	DNA-binding transcription factor activity
I5Q76_RS04855	COG0738	Major facilitator superfamily
I5Q76_RS04860	COG0235	Class ii aldolase
I5Q76_RS04885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5Q76_RS04900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
I5Q76_RS04905	COG2011	ABC-type metal ion transport system permease component
I5Q76_RS04910	COG1464	Belongs to the NlpA lipoprotein family
I5Q76_RS04915	COG0477	Major facilitator Superfamily
I5Q76_RS04925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5Q76_RS04930	COG1760	l-serine dehydratase
I5Q76_RS04935	COG0814	amino acid
I5Q76_RS04940	COG1611	Belongs to the LOG family
I5Q76_RS04955	COG3098	single-species biofilm formation
I5Q76_RS04960	COG0564	pseudouridine synthase activity
I5Q76_RS04965	COG0716	FMN binding
I5Q76_RS04970	COG2271	Major facilitator Superfamily
I5Q76_RS04975	COG4948	Mandelate Racemase Muconate Lactonizing
I5Q76_RS04980	COG4948	Mandelate Racemase Muconate Lactonizing
I5Q76_RS04985	COG1929	Belongs to the glycerate kinase type-1 family
I5Q76_RS04990	COG3437	response regulator, receiver
I5Q76_RS04990	COG2205	protein histidine kinase activity
I5Q76_RS04990	COG4999	Histidine kinase
I5Q76_RS04990	COG3850	Histidine kinase
I5Q76_RS05000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I5Q76_RS05005	COG3956	TIGRFAM MazG family protein
I5Q76_RS05025	COG0602	queuosine metabolic process
I5Q76_RS05030	COG0720	synthase
I5Q76_RS05050	COG1203	CRISPR-associated helicase, Cas3
I5Q76_RS05065	COG1857	crispr-associated protein
I5Q76_RS05085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I5Q76_RS05100	COG2234	aminopeptidase activity
I5Q76_RS05160	COG1388	LysM domain
I5Q76_RS05160	COG4942	peptidase
I5Q76_RS05165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
I5Q76_RS05190	COG0163	prenyltransferase activity
I5Q76_RS05195	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
I5Q76_RS05235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5Q76_RS05240	COG4558	Periplasmic binding protein
I5Q76_RS05245	COG3720	iron ion transport
I5Q76_RS05250	COG4771	TonB-dependent receptor
I5Q76_RS05250	COG1629	transport
I5Q76_RS05265	COG0679	Auxin Efflux Carrier
I5Q76_RS05280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I5Q76_RS05285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I5Q76_RS05290	COG1121	(ABC) transporter
I5Q76_RS05300	COG1609	Transcriptional regulator
I5Q76_RS05305	COG1940	carbohydrate kinase activity
I5Q76_RS05310	COG1447	Phosphotransferase system cellobiose-specific component IIA
I5Q76_RS05315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5Q76_RS05320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5Q76_RS05325	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5Q76_RS05330	COG4580	involved in the transport of maltose and maltodextrins
I5Q76_RS05340	COG2723	6-phospho-beta-galactosidase activity
I5Q76_RS05350	COG0309	Hydrogenase expression formation protein (HypE)
I5Q76_RS05355	COG0409	Hydrogenase expression formation protein
I5Q76_RS05360	COG0298	carbon dioxide binding
I5Q76_RS05365	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
I5Q76_RS05380	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
I5Q76_RS05385	COG0651	ATP synthesis coupled electron transport
I5Q76_RS05390	COG0650	Formate hydrogenlyase subunit 4
I5Q76_RS05395	COG3261	NADH dehydrogenase
I5Q76_RS05395	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
I5Q76_RS05400	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
I5Q76_RS05405	COG3260	NADH ubiquinone oxidoreductase 20
I5Q76_RS05415	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
I5Q76_RS05425	COG2723	6-phospho-beta-galactosidase activity
I5Q76_RS05430	COG1263	PTS System
I5Q76_RS05430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5Q76_RS05435	COG1609	Transcriptional regulator
I5Q76_RS05440	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
I5Q76_RS05445	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
I5Q76_RS05450	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
I5Q76_RS05475	COG1349	DNA-binding transcription factor activity
I5Q76_RS05480	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS05485	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS05495	COG3732	PTS system glucitol sorbitol-specific
I5Q76_RS05500	COG3730	PTS system glucitol sorbitol-specific
I5Q76_RS05505	COG2951	lytic endotransglycosylase activity
I5Q76_RS05510	COG1121	(ABC) transporter
I5Q76_RS05515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I5Q76_RS05525	COG1546	Belongs to the CinA family
I5Q76_RS05545	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
I5Q76_RS05575	COG2823	Periplasmic or secreted lipoprotein
I5Q76_RS05580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I5Q76_RS05585	COG1238	metal cluster binding
I5Q76_RS05605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
I5Q76_RS05610	COG2814	Major facilitator Superfamily
I5Q76_RS05615	COG1566	PFAM secretion protein HlyD family protein
I5Q76_RS05620	COG1846	Transcriptional regulator
I5Q76_RS05630	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
I5Q76_RS05640	COG4176	ABC-type proline glycine betaine transport system permease component
I5Q76_RS05655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I5Q76_RS05665	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
I5Q76_RS05670	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I5Q76_RS05675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5Q76_RS05680	COG4575	ribosome binding
I5Q76_RS05695	COG2916	Histone family protein nucleoid-structuring protein H-NS
I5Q76_RS05710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I5Q76_RS05715	COG0640	Transcriptional regulator
I5Q76_RS05725	COG0583	DNA-binding transcription factor activity
I5Q76_RS05730	COG3284	Transcriptional regulator
I5Q76_RS05740	COG3539	Fimbrial protein
I5Q76_RS05745	COG3121	Chaperone
I5Q76_RS05765	COG3188	usher protein
I5Q76_RS05775	COG3539	Fimbrial protein
I5Q76_RS05780	COG2197	response regulator
I5Q76_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS05805	COG0235	Class ii aldolase
I5Q76_RS05815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5Q76_RS05850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5Q76_RS05855	COG2207	Transcriptional regulator
I5Q76_RS05855	COG3708	Transcriptional regulator
I5Q76_RS05875	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
I5Q76_RS05880	COG0756	dUTP diphosphatase activity
I5Q76_RS05885	COG4974	Belongs to the 'phage' integrase family
I5Q76_RS05920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I5Q76_RS05960	COG4695	Portal protein
I5Q76_RS06125	COG2867	negative regulation of translational initiation
I5Q76_RS06140	COG0497	DNA recombination
I5Q76_RS06155	COG4536	flavin adenine dinucleotide binding
I5Q76_RS06160	COG4137	Cytochrome C assembly protein
I5Q76_RS06165	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
I5Q76_RS06200	COG2885	chlorophyll binding
I5Q76_RS06205	COG2199	diguanylate cyclase activity
I5Q76_RS06215	COG3039	Transposase
I5Q76_RS06220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
I5Q76_RS06225	COG0287	Prephenate dehydrogenase
I5Q76_RS06225	COG1605	Chorismate mutase
I5Q76_RS06235	COG0077	Prephenate dehydratase
I5Q76_RS06235	COG1605	Chorismate mutase
I5Q76_RS06245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
I5Q76_RS06250	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I5Q76_RS06265	COG0542	response to heat
I5Q76_RS06290	COG0477	Major facilitator Superfamily
I5Q76_RS06295	COG5544	Lipoprotein
I5Q76_RS06300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I5Q76_RS06310	COG3148	PFAM DTW domain containing protein
I5Q76_RS06315	COG3118	belongs to the thioredoxin family
I5Q76_RS06320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I5Q76_RS06335	COG0513	Belongs to the DEAD box helicase family
I5Q76_RS06345	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
I5Q76_RS06360	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
I5Q76_RS06365	COG3026	antisigma factor binding
I5Q76_RS06370	COG3086	response to oxidative stress
I5Q76_RS06380	COG0681	Belongs to the peptidase S26 family
I5Q76_RS06400	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
I5Q76_RS06410	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
I5Q76_RS06415	COG1737	Transcriptional regulator
I5Q76_RS06420	COG0560	Phosphoserine phosphatase
I5Q76_RS06435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
I5Q76_RS06435	COG0047	phosphoribosylformylglycinamidine synthase activity
I5Q76_RS06440	COG2205	protein histidine kinase activity
I5Q76_RS06445	COG3170	Tfp pilus assembly protein FimV
I5Q76_RS06450	COG2204	response regulator
I5Q76_RS06455	COG0347	Belongs to the P(II) protein family
I5Q76_RS06460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I5Q76_RS06460	COG1017	nitric oxide dioxygenase activity
I5Q76_RS06470	COG2259	Doxx family
I5Q76_RS06475	COG1940	carbohydrate kinase activity
I5Q76_RS06480	COG0457	Tetratricopeptide repeat
I5Q76_RS06485	COG0477	Major facilitator Superfamily
I5Q76_RS06485	COG2814	Major facilitator Superfamily
I5Q76_RS06490	COG2017	converts alpha-aldose to the beta-anomer
I5Q76_RS06495	COG2814	Major facilitator Superfamily
I5Q76_RS06500	COG3711	transcriptional antiterminator
I5Q76_RS06505	COG3683	transport system, periplasmic component
I5Q76_RS06510	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
I5Q76_RS06540	COG0822	iron-sulfur transferase activity
I5Q76_RS06560	COG0633	Ferredoxin
I5Q76_RS06565	COG2975	iron-sulfur cluster assembly
I5Q76_RS06585	COG2897	thiosulfate sulfurtransferase activity
I5Q76_RS06590	COG2373	Large extracellular alpha-helical protein
I5Q76_RS06595	COG4953	penicillin-binding protein 1C
I5Q76_RS06625	COG2976	Protein conserved in bacteria
I5Q76_RS06655	COG1645	bacterial-type flagellum-dependent swarming motility
I5Q76_RS06665	COG0516	GMP reductase activity
I5Q76_RS06665	COG0517	IMP dehydrogenase activity
I5Q76_RS06675	COG3119	arylsulfatase activity
I5Q76_RS06680	COG0641	radical SAM
I5Q76_RS06700	COG2200	EAL domain
I5Q76_RS06715	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
I5Q76_RS06730	COG2723	6-phospho-beta-galactosidase activity
I5Q76_RS06740	COG2233	PERMEase
I5Q76_RS06755	COG1393	Belongs to the ArsC family
I5Q76_RS06760	COG4783	chaperone-mediated protein folding
I5Q76_RS06770	COG0628	permease
I5Q76_RS06775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I5Q76_RS06780	COG2716	regulation of RNA biosynthetic process
I5Q76_RS06790	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
I5Q76_RS06800	COG2321	neutral zinc metallopeptidase
I5Q76_RS06805	COG1444	tRNA N-acetyltransferase activity
I5Q76_RS06810	COG0400	carboxylic ester hydrolase activity
I5Q76_RS06825	COG1393	Belongs to the ArsC family
I5Q76_RS06835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5Q76_RS06840	COG0493	'glutamate synthase
I5Q76_RS06840	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
I5Q76_RS06850	COG5342	invasion associated locus B
I5Q76_RS06855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
I5Q76_RS06860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
I5Q76_RS06870	COG4810	utilization protein
I5Q76_RS06960	COG0860	N-Acetylmuramoyl-L-alanine amidase
I5Q76_RS06980	COG2837	iron assimilation
I5Q76_RS06990	COG4150	thiosulfate binding
I5Q76_RS06995	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
I5Q76_RS07000	COG4208	sulfate ABC transporter
I5Q76_RS07005	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
I5Q76_RS07015	COG4319	ketosteroid isomerase
I5Q76_RS07050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I5Q76_RS07070	COG3530	Putative quorum-sensing-regulated virulence factor
I5Q76_RS07075	COG0385	Bile acid
I5Q76_RS07080	COG0583	DNA-binding transcription factor activity
I5Q76_RS07110	COG3415	Transposase
I5Q76_RS07115	COG3415	Transposase
I5Q76_RS07130	COG2199	diguanylate cyclase activity
I5Q76_RS07130	COG2200	EAL domain
I5Q76_RS07135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I5Q76_RS07150	COG0667	Aldo Keto reductase
I5Q76_RS07155	COG3961	Belongs to the TPP enzyme family
I5Q76_RS07170	COG3279	Response regulator of the LytR AlgR family
I5Q76_RS07175	COG3275	phosphorelay sensor kinase activity
I5Q76_RS07190	COG0436	Aminotransferase
I5Q76_RS07200	COG2807	transmembrane transport
I5Q76_RS07205	COG0590	tRNA wobble adenosine to inosine editing
I5Q76_RS07210	COG0583	DNA-binding transcription factor activity
I5Q76_RS07245	COG2814	Major facilitator Superfamily
I5Q76_RS07250	COG4221	oxidoreductase activity
I5Q76_RS07255	COG2171	N-acyltransferase activity
I5Q76_RS07310	COG1122	ATPase activity
I5Q76_RS07345	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS07345	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5Q76_RS07350	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS07350	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5Q76_RS07355	COG3715	PTS system
I5Q76_RS07360	COG3716	PTS system mannose fructose sorbose family IID component
I5Q76_RS07375	COG2376	Dihydroxyacetone kinase
I5Q76_RS07380	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
I5Q76_RS07385	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
I5Q76_RS07415	COG3121	Chaperone
I5Q76_RS07420	COG3188	usher protein
I5Q76_RS07440	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
I5Q76_RS07460	COG2116	formate transmembrane transporter activity
I5Q76_RS07465	COG2853	Lipoprotein
I5Q76_RS07475	COG3691	Protein conserved in bacteria
I5Q76_RS07490	COG2062	phosphohistidine phosphatase, SixA
I5Q76_RS07515	COG0730	response to heat
I5Q76_RS07520	COG3101	peptidyl-lysine hydroxylation
I5Q76_RS07535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I5Q76_RS07555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I5Q76_RS07565	COG0586	Pfam SNARE associated Golgi protein
I5Q76_RS07575	COG0285	dihydrofolate synthase activity
I5Q76_RS07580	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
I5Q76_RS07585	COG1286	toxin biosynthetic process
I5Q76_RS07590	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
I5Q76_RS07595	COG0163	prenyltransferase activity
I5Q76_RS07620	COG4160	amino acid transport
I5Q76_RS07625	COG4598	ABC transporter
I5Q76_RS07640	COG1090	epimerase
I5Q76_RS07645	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
I5Q76_RS07650	COG0625	glutathione transferase activity
I5Q76_RS07655	COG0625	glutathione transferase activity
I5Q76_RS07660	COG0622	Phosphoesterase
I5Q76_RS07665	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
I5Q76_RS07670	COG0280	phosphate acetyltransferase
I5Q76_RS07670	COG0857	belongs to the CobB CobQ family
I5Q76_RS07690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I5Q76_RS07695	COG0471	metal ion transport
I5Q76_RS07695	COG0490	domain, Protein
I5Q76_RS07705	COG0436	Aminotransferase
I5Q76_RS07710	COG0583	DNA-binding transcription factor activity
I5Q76_RS07765	COG0839	Belongs to the complex I subunit 6 family
I5Q76_RS07775	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
I5Q76_RS07780	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
I5Q76_RS07795	COG2153	protein acetylation
I5Q76_RS07800	COG1169	isochorismate synthase
I5Q76_RS07825	COG0318	PFAM AMP-dependent synthetase and ligase
I5Q76_RS07835	COG5464	transposase or invertase
I5Q76_RS07850	COG1414	Transcriptional regulator
I5Q76_RS07860	COG2271	Major facilitator Superfamily
I5Q76_RS07870	COG0247	lactate metabolic process
I5Q76_RS07880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I5Q76_RS07885	COG2271	Major facilitator Superfamily
I5Q76_RS07890	COG0584	glycerophosphoryl diester phosphodiesterase
I5Q76_RS07895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I5Q76_RS07920	COG0784	Response regulator, receiver
I5Q76_RS07920	COG2205	protein histidine kinase activity
I5Q76_RS07930	COG2198	Histidine kinase
I5Q76_RS07930	COG0642	Histidine kinase
I5Q76_RS07945	COG2169	Transcriptional regulator
I5Q76_RS07945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I5Q76_RS07950	COG3145	DNA-N1-methyladenine dioxygenase activity
I5Q76_RS07955	COG4615	Cyclic peptide transporter
I5Q76_RS07960	COG2239	Acts as a magnesium transporter
I5Q76_RS07965	COG0659	secondary active sulfate transmembrane transporter activity
I5Q76_RS07980	COG0628	permease
I5Q76_RS08005	COG1349	DNA-binding transcription factor activity
I5Q76_RS08010	COG0494	nUDIX hydrolase
I5Q76_RS08030	COG1061	Type III restriction enzyme res subunit
I5Q76_RS08035	COG1187	pseudouridine synthase activity
I5Q76_RS08040	COG2814	Major facilitator Superfamily
I5Q76_RS08050	COG4172	Belongs to the ABC transporter superfamily
I5Q76_RS08055	COG4239	(ABC) transporter, permease
I5Q76_RS08060	COG4174	ABC transporter (Permease)
I5Q76_RS08065	COG4166	transmembrane transport
I5Q76_RS08070	COG2200	EAL domain
I5Q76_RS08075	COG0791	NLP P60 protein
I5Q76_RS08080	COG0671	phosphoesterase, PA-phosphatase related
I5Q76_RS08085	COG0523	cobalamin synthesis protein
I5Q76_RS08090	COG0246	Mannitol dehydrogenase
I5Q76_RS08095	COG1312	Catalyzes the dehydration of D-mannonate
I5Q76_RS08115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS08115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS08120	COG1105	Belongs to the carbohydrate kinase PfkB family
I5Q76_RS08125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5Q76_RS08125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5Q76_RS08125	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
I5Q76_RS08135	COG2855	membrane
I5Q76_RS08140	COG0583	DNA-binding transcription factor activity
I5Q76_RS08145	COG0833	amino acid
I5Q76_RS08150	COG4771	TonB-dependent receptor
I5Q76_RS08165	COG2311	Membrane
I5Q76_RS08180	COG1129	ABC transporter
I5Q76_RS08190	COG2949	membrane
I5Q76_RS08200	COG1346	cytolysis
I5Q76_RS08210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I5Q76_RS08215	COG3659	wide pore channel activity
I5Q76_RS08230	COG2723	6-phospho-beta-galactosidase activity
I5Q76_RS08235	COG1538	Outer membrane efflux protein
I5Q76_RS08240	COG0586	Pfam SNARE associated Golgi protein
I5Q76_RS08250	COG1686	Belongs to the peptidase S11 family
I5Q76_RS08260	COG0277	FAD linked oxidase domain protein
I5Q76_RS08265	COG1472	Belongs to the glycosyl hydrolase 3 family
I5Q76_RS08270	COG1732	Glycine betaine
I5Q76_RS08275	COG1174	glycine betaine transport
I5Q76_RS08280	COG1125	glycine betaine transport
I5Q76_RS08285	COG1174	glycine betaine transport
I5Q76_RS08295	COG3275	phosphorelay sensor kinase activity
I5Q76_RS08305	COG4807	Protein conserved in bacteria
I5Q76_RS08325	COG5455	response to cobalt ion
I5Q76_RS08330	COG0583	DNA-binding transcription factor activity
I5Q76_RS08335	COG2252	PERMEase
I5Q76_RS08345	COG0583	DNA-binding transcription factor activity
I5Q76_RS08360	COG0351	phosphomethylpyrimidine kinase
I5Q76_RS08365	COG1830	Aldolase
I5Q76_RS08375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
I5Q76_RS08400	COG1070	Carbohydrate kinase
I5Q76_RS08410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I5Q76_RS08415	COG4948	Mandelate Racemase Muconate Lactonizing
I5Q76_RS08420	COG0747	negative chemotaxis
I5Q76_RS08425	COG0601	transmembrane transport
I5Q76_RS08430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I5Q76_RS08435	COG0444	Belongs to the ABC transporter superfamily
I5Q76_RS08440	COG4608	Belongs to the ABC transporter superfamily
I5Q76_RS08450	COG0826	peptidase U32
I5Q76_RS08455	COG0745	RESPONSE REGULATOR receiver
I5Q76_RS08460	COG2205	protein histidine kinase activity
I5Q76_RS08485	COG1301	dicarboxylic acid transport
I5Q76_RS08505	COG5002	protein histidine kinase activity
I5Q76_RS08510	COG0443	Heat shock 70 kDa protein
I5Q76_RS08515	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
I5Q76_RS08530	COG2982	Protein involved in outer membrane biogenesis
I5Q76_RS08535	COG1253	flavin adenine dinucleotide binding
I5Q76_RS08580	COG0438	transferase activity, transferring glycosyl groups
I5Q76_RS08585	COG0438	transferase activity, transferring glycosyl groups
I5Q76_RS08595	COG0438	transferase activity, transferring glycosyl groups
I5Q76_RS08600	COG0438	transferase activity, transferring glycosyl groups
I5Q76_RS08685	COG0438	transferase activity, transferring glycosyl groups
I5Q76_RS08710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
I5Q76_RS08740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I5Q76_RS08745	COG0583	DNA-binding transcription factor activity
I5Q76_RS08755	COG0531	amino acid
I5Q76_RS08760	COG0640	Transcriptional regulator
I5Q76_RS08765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
I5Q76_RS08770	COG2925	Exonuclease
I5Q76_RS08780	COG3344	reverse transcriptase
I5Q76_RS08790	COG1289	transmembrane transporter activity
I5Q76_RS08810	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
I5Q76_RS08820	COG1942	4-Oxalocrotonate Tautomerase
I5Q76_RS08825	COG0583	DNA-binding transcription factor activity
I5Q76_RS08830	COG0095	Lipoate-protein ligase
I5Q76_RS08835	COG0477	Major facilitator Superfamily
I5Q76_RS08845	COG5001	Diguanylate cyclase
I5Q76_RS08845	COG3300	MHYT domain
I5Q76_RS08855	COG3615	Tellurite resistance protein tehB
I5Q76_RS08880	COG3706	GGDEF domain
I5Q76_RS08900	COG0534	Mate efflux family protein
I5Q76_RS08910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
I5Q76_RS08930	COG0604	alcohol dehydrogenase
I5Q76_RS08935	COG1309	transcriptional regulator
I5Q76_RS08940	COG0025	NhaP-type Na H and K H
I5Q76_RS08985	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
I5Q76_RS08995	COG1418	mRNA catabolic process
I5Q76_RS09000	COG0270	DNA (cytosine-5-)-methyltransferase activity
I5Q76_RS09005	COG3727	T/G mismatch-specific endonuclease activity
I5Q76_RS09010	COG0697	spore germination
I5Q76_RS09015	COG2354	Protein conserved in bacteria
I5Q76_RS09045	COG0366	Alpha amylase catalytic
I5Q76_RS09050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5Q76_RS09060	COG0765	amino acid transport
I5Q76_RS09065	COG1126	abc transporter atp-binding protein
I5Q76_RS09070	COG2197	response regulator
I5Q76_RS09080	COG2197	response regulator
I5Q76_RS09115	COG3318	Belongs to the UPF0149 family
I5Q76_RS09115	COG3012	SEC-C Motif Domain Protein
I5Q76_RS09120	COG0814	amino acid
I5Q76_RS09130	COG1528	Iron-storage protein
I5Q76_RS09145	COG0477	Major facilitator Superfamily
I5Q76_RS09155	COG2211	Major facilitator Superfamily
I5Q76_RS09165	COG1528	Iron-storage protein
I5Q76_RS09175	COG1879	ABC-type sugar transport system periplasmic component
I5Q76_RS09185	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS09210	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
I5Q76_RS09220	COG3102	Protein conserved in bacteria
I5Q76_RS09240	COG3788	relative of glutathione S-transferase, MAPEG superfamily
I5Q76_RS09245	COG1801	Protein of unknown function DUF72
I5Q76_RS09250	COG1335	isochorismatase
I5Q76_RS09260	COG0494	nUDIX hydrolase
I5Q76_RS09285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I5Q76_RS09295	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
I5Q76_RS09300	COG0739	heme binding
I5Q76_RS09305	COG1560	Kdo2-lipid A biosynthetic process
I5Q76_RS09315	COG1737	Transcriptional regulator
I5Q76_RS09325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
I5Q76_RS09330	COG0129	dihydroxy-acid dehydratase activity
I5Q76_RS09335	COG0800	Aldolase
I5Q76_RS09345	COG3141	response to X-ray
I5Q76_RS09350	COG2979	Protein of unknown function (DUF533)
I5Q76_RS09355	COG1770	oligopeptidase
I5Q76_RS09360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I5Q76_RS09370	COG2372	response to copper ion
I5Q76_RS09375	COG1276	copper resistance
I5Q76_RS09390	COG2990	Protein conserved in bacteria
I5Q76_RS09415	COG3008	intermembrane lipid transfer
I5Q76_RS09420	COG2995	paraquat-inducible protein a
I5Q76_RS09425	COG1956	GAF domain-containing protein
I5Q76_RS09445	COG2814	Major facilitator Superfamily
I5Q76_RS09450	COG1414	Transcriptional regulator
I5Q76_RS09480	COG0768	penicillin binding
I5Q76_RS09485	COG2226	methyltransferase
I5Q76_RS09500	COG3716	PTS system mannose fructose sorbose family IID component
I5Q76_RS09505	COG3715	PTS system
I5Q76_RS09510	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5Q76_RS09510	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS09515	COG1253	flavin adenine dinucleotide binding
I5Q76_RS09520	COG2200	EAL domain
I5Q76_RS09525	COG1760	l-serine dehydratase
I5Q76_RS09545	COG0251	oxidation-reduction process
I5Q76_RS09550	COG1199	ATP-dependent helicase activity
I5Q76_RS09560	COG3065	identical protein binding
I5Q76_RS09570	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
I5Q76_RS09580	COG2894	cell division
I5Q76_RS09595	COG0179	Fumarylacetoacetate (FAA) hydrolase
I5Q76_RS09625	COG2719	SpoVR family
I5Q76_RS09650	COG1619	proteins homologs of microcin C7 resistance protein MccF
I5Q76_RS09660	COG4774	siderophore transport
I5Q76_RS09675	COG2308	Evidence 4 Homologs of previously reported genes of
I5Q76_RS09720	COG0583	DNA-binding transcription factor activity
I5Q76_RS09725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
I5Q76_RS09740	COG1882	Formate acetyltransferase
I5Q76_RS09775	COG0583	DNA-binding transcription factor activity
I5Q76_RS09805	COG0583	DNA-binding transcription factor activity
I5Q76_RS09820	COG3122	Protein conserved in bacteria
I5Q76_RS09840	COG2885	chlorophyll binding
I5Q76_RS09875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
I5Q76_RS09940	COG0012	GTP binding
I5Q76_RS09960	COG0659	secondary active sulfate transmembrane transporter activity
I5Q76_RS09990	COG2890	protein-(glutamine-N5) methyltransferase activity
I5Q76_RS10010	COG0387	Pfam Sodium calcium exchanger
I5Q76_RS10015	COG4572	Cation transport regulator
I5Q76_RS10020	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
I5Q76_RS10030	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
I5Q76_RS10035	COG3707	response regulator
I5Q76_RS10040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5Q76_RS10050	COG1116	anion transmembrane transporter activity
I5Q76_RS10055	COG2146	nitrite reductase [NAD(P)H] activity
I5Q76_RS10055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I5Q76_RS10060	COG0243	molybdopterin cofactor binding
I5Q76_RS10065	COG4932	domain protein
I5Q76_RS10070	COG2197	response regulator
I5Q76_RS10075	COG3850	Histidine kinase
I5Q76_RS10080	COG2223	nitrite transmembrane transporter activity
I5Q76_RS10090	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
I5Q76_RS10095	COG1140	nitrate reductase beta subunit
I5Q76_RS10100	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
I5Q76_RS10105	COG2181	nitrate reductase activity
I5Q76_RS10115	COG1522	sequence-specific DNA binding
I5Q76_RS10150	COG0788	formyltetrahydrofolate deformylase activity
I5Q76_RS10160	COG1752	Esterase of the alpha-beta hydrolase superfamily
I5Q76_RS10165	COG0745	RESPONSE REGULATOR receiver
I5Q76_RS10170	COG1210	Utp--glucose-1-phosphate uridylyltransferase
I5Q76_RS10175	COG2916	Histone family protein nucleoid-structuring protein H-NS
I5Q76_RS10185	COG1435	thymidine kinase activity
I5Q76_RS10190	COG1454	alcohol dehydrogenase
I5Q76_RS10190	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS10200	COG2095	MarC family integral membrane protein
I5Q76_RS10205	COG4166	transmembrane transport
I5Q76_RS10210	COG0601	transmembrane transport
I5Q76_RS10215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I5Q76_RS10220	COG0444	Belongs to the ABC transporter superfamily
I5Q76_RS10230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I5Q76_RS10250	COG2353	YceI-like domain
I5Q76_RS10260	COG2350	Protein conserved in bacteria
I5Q76_RS10270	COG3001	Fructosamine kinase
I5Q76_RS10280	COG1105	Belongs to the carbohydrate kinase PfkB family
I5Q76_RS10285	COG3137	Salt-induced outer membrane protein
I5Q76_RS10325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I5Q76_RS10325	COG0072	phenylalanine-tRNA ligase activity
I5Q76_RS10345	COG0583	DNA-binding transcription factor activity
I5Q76_RS10365	COG0386	Belongs to the glutathione peroxidase family
I5Q76_RS10375	COG0791	NLP P60 protein
I5Q76_RS10385	COG4256	Hemin uptake protein
I5Q76_RS10390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
I5Q76_RS10405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I5Q76_RS10405	COG0574	Belongs to the PEP-utilizing enzyme family
I5Q76_RS10415	COG0628	permease
I5Q76_RS10420	COG0277	FAD linked oxidase domain protein
I5Q76_RS10420	COG0247	lactate metabolic process
I5Q76_RS10425	COG2050	protein possibly involved in aromatic compounds catabolism
I5Q76_RS10430	COG2261	transglycosylase associated protein
I5Q76_RS10455	COG1120	ATPase activity
I5Q76_RS10460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5Q76_RS10470	COG0583	DNA-binding transcription factor activity
I5Q76_RS10495	COG1304	FMN binding
I5Q76_RS10500	COG1309	transcriptional regulator
I5Q76_RS10520	COG0316	Belongs to the HesB IscA family
I5Q76_RS10525	COG0719	Fe-S assembly protein
I5Q76_RS10530	COG0396	ATPase activity
I5Q76_RS10535	COG0719	Fe-S assembly protein
I5Q76_RS10550	COG1376	ErfK ybiS ycfS ynhG family protein
I5Q76_RS10580	COG1309	transcriptional regulator
I5Q76_RS10585	COG3185	4-Hydroxyphenylpyruvate dioxygenase
I5Q76_RS10585	COG1082	Xylose isomerase domain protein TIM barrel
I5Q76_RS10590	COG2271	Major facilitator Superfamily
I5Q76_RS10595	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
I5Q76_RS10605	COG1120	ATPase activity
I5Q76_RS10610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5Q76_RS10615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I5Q76_RS10620	COG1414	Transcriptional regulator
I5Q76_RS10655	COG2814	Major facilitator Superfamily
I5Q76_RS10675	COG0583	DNA-binding transcription factor activity
I5Q76_RS10680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5Q76_RS10700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5Q76_RS10705	COG1116	anion transmembrane transporter activity
I5Q76_RS10710	COG4774	siderophore transport
I5Q76_RS10715	COG1120	ATPase activity
I5Q76_RS10720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5Q76_RS10725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5Q76_RS10745	COG0765	amino acid transport
I5Q76_RS10750	COG1126	abc transporter atp-binding protein
I5Q76_RS10790	COG3383	formate dehydrogenase (NAD+) activity
I5Q76_RS10795	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
I5Q76_RS10805	COG1175	transmembrane transport
I5Q76_RS10835	COG4133	protoheme IX ABC transporter activity
I5Q76_RS10840	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I5Q76_RS10845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I5Q76_RS10860	COG1138	Cytochrome C-type biogenesis protein
I5Q76_RS10865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I5Q76_RS10870	COG3088	subunit of a heme lyase
I5Q76_RS10870	COG4235	cytochrome complex assembly
I5Q76_RS10895	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
I5Q76_RS10910	COG5002	protein histidine kinase activity
I5Q76_RS10910	COG3850	Histidine kinase
I5Q76_RS10915	COG0745	RESPONSE REGULATOR receiver
I5Q76_RS10930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5Q76_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS10970	COG2610	gluconate transmembrane transporter activity
I5Q76_RS10975	COG1250	3-hydroxyacyl-CoA dehydrogenase
I5Q76_RS10985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
I5Q76_RS10995	COG0583	DNA-binding transcription factor activity
I5Q76_RS11020	COG0277	FAD linked oxidase domain protein
I5Q76_RS11025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5Q76_RS11050	COG0402	S-adenosylhomocysteine deaminase activity
I5Q76_RS11090	COG0604	alcohol dehydrogenase
I5Q76_RS11090	COG3321	synthase
I5Q76_RS11090	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS11120	COG4608	Belongs to the ABC transporter superfamily
I5Q76_RS11150	COG0346	lactoylglutathione lyase activity
I5Q76_RS11155	COG1349	DNA-binding transcription factor activity
I5Q76_RS11190	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
I5Q76_RS11245	COG0307	riboflavin synthase, alpha
I5Q76_RS11250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
I5Q76_RS11255	COG2814	Major facilitator Superfamily
I5Q76_RS11260	COG0583	DNA-binding transcription factor activity
I5Q76_RS11275	COG2814	Major facilitator Superfamily
I5Q76_RS11290	COG0791	NLP P60 protein
I5Q76_RS11295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
I5Q76_RS11305	COG0346	lactoylglutathione lyase activity
I5Q76_RS11310	COG1902	pentaerythritol trinitrate reductase activity
I5Q76_RS11315	COG1309	transcriptional regulator
I5Q76_RS11320	COG3313	Fe-S protein
I5Q76_RS11325	COG4989	oxidoreductase activity
I5Q76_RS11330	COG2032	superoxide dismutase activity
I5Q76_RS11335	COG1289	transmembrane transporter activity
I5Q76_RS11340	COG1566	PFAM secretion protein HlyD family protein
I5Q76_RS11355	COG3706	GGDEF domain
I5Q76_RS11370	COG3895	Periplasmic Protein
I5Q76_RS11385	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
I5Q76_RS11390	COG0625	glutathione transferase activity
I5Q76_RS11400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
I5Q76_RS11410	COG4659	FMN binding
I5Q76_RS11445	COG2723	6-phospho-beta-galactosidase activity
I5Q76_RS11455	COG0673	inositol 2-dehydrogenase activity
I5Q76_RS11465	COG2814	Major facilitator Superfamily
I5Q76_RS11485	COG3038	cytochrome b561
I5Q76_RS11505	COG0583	DNA-binding transcription factor activity
I5Q76_RS11510	COG3485	protocatechuate 3,4-dioxygenase
I5Q76_RS11515	COG3485	protocatechuate 3,4-dioxygenase
I5Q76_RS11520	COG5383	Protein conserved in bacteria
I5Q76_RS11525	COG2272	Belongs to the type-B carboxylesterase lipase family
I5Q76_RS11540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I5Q76_RS11545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I5Q76_RS11550	COG1275	C4-dicarboxylate transporter malic acid transport protein
I5Q76_RS11555	COG0500	methyltransferase
I5Q76_RS11570	COG2207	Transcriptional regulator
I5Q76_RS11570	COG3708	Transcriptional regulator
I5Q76_RS11575	COG3135	benzoate transporter
I5Q76_RS11580	COG1396	sequence-specific DNA binding
I5Q76_RS11590	COG0826	peptidase U32
I5Q76_RS11610	COG1294	oxidase, subunit
I5Q76_RS11615	COG1271	oxidase subunit
I5Q76_RS11620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5Q76_RS11625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
I5Q76_RS11630	COG3842	ATPase activity
I5Q76_RS11635	COG1176	ABC-type spermidine putrescine transport system, permease component I
I5Q76_RS11640	COG1177	transmembrane transport
I5Q76_RS11645	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS11680	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS11685	COG0747	negative chemotaxis
I5Q76_RS11695	COG3238	Protein conserved in bacteria
I5Q76_RS11700	COG1247	-acetyltransferase
I5Q76_RS11710	COG2130	NADP-dependent
I5Q76_RS11720	COG3691	Protein conserved in bacteria
I5Q76_RS11730	COG4772	TonB-dependent receptor
I5Q76_RS11755	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
I5Q76_RS11760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5Q76_RS11765	COG1473	amidohydrolase
I5Q76_RS11770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5Q76_RS11775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5Q76_RS11785	COG0765	amino acid transport
I5Q76_RS11790	COG1126	abc transporter atp-binding protein
I5Q76_RS11800	COG0625	glutathione transferase activity
I5Q76_RS11820	COG2211	Major facilitator Superfamily
I5Q76_RS11835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I5Q76_RS11840	COG3842	ATPase activity
I5Q76_RS11845	COG1840	ABC-type Fe3 transport system, periplasmic component
I5Q76_RS11850	COG1178	ABC-type Fe3 transport system permease component
I5Q76_RS11855	COG2162	N-hydroxyarylamine O-acetyltransferase activity
I5Q76_RS11860	COG2181	nitrate reductase activity
I5Q76_RS11865	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
I5Q76_RS11870	COG1140	nitrate reductase beta subunit
I5Q76_RS11875	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
I5Q76_RS11895	COG1414	Transcriptional regulator
I5Q76_RS11900	COG4948	Mandelate Racemase Muconate Lactonizing
I5Q76_RS11905	COG4829	muconolactone delta-isomerase
I5Q76_RS11910	COG3485	protocatechuate 3,4-dioxygenase
I5Q76_RS11920	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
I5Q76_RS11945	COG0437	4 iron, 4 sulfur cluster binding
I5Q76_RS11950	COG2864	formate dehydrogenase
I5Q76_RS11965	COG2326	polyphosphate kinase activity
I5Q76_RS11975	COG2814	Major facilitator Superfamily
I5Q76_RS11985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5Q76_RS11995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I5Q76_RS12005	COG0747	negative chemotaxis
I5Q76_RS12010	COG1064	alcohol dehydrogenase
I5Q76_RS12025	COG0488	(ABC) transporter
I5Q76_RS12065	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS12070	COG3729	General stress protein
I5Q76_RS12080	COG3685	Protein conserved in bacteria
I5Q76_RS12090	COG0366	Alpha amylase catalytic
I5Q76_RS12100	COG2323	membrane
I5Q76_RS12110	COG3111	PFAM Bacterial OB fold (BOF) protein
I5Q76_RS12120	COG1764	response to oxidative stress
I5Q76_RS12145	COG3781	membrane
I5Q76_RS12150	COG0243	molybdopterin cofactor binding
I5Q76_RS12155	COG0583	DNA-binding transcription factor activity
I5Q76_RS12160	COG1447	Phosphotransferase system cellobiose-specific component IIA
I5Q76_RS12165	COG2814	Major facilitator Superfamily
I5Q76_RS12170	COG1285	pathogenesis
I5Q76_RS12175	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
I5Q76_RS12185	COG0583	DNA-binding transcription factor activity
I5Q76_RS12205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
I5Q76_RS12205	COG0519	Catalyzes the synthesis of GMP from XMP
I5Q76_RS12245	COG0596	Alpha beta hydrolase
I5Q76_RS12255	COG2205	protein histidine kinase activity
I5Q76_RS12270	COG0076	glutamate decarboxylase activity
I5Q76_RS12275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
I5Q76_RS12280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5Q76_RS12285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5Q76_RS12290	COG1116	anion transmembrane transporter activity
I5Q76_RS12295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
I5Q76_RS12310	COG0673	inositol 2-dehydrogenase activity
I5Q76_RS12325	COG3706	GGDEF domain
I5Q76_RS12345	COG0402	S-adenosylhomocysteine deaminase activity
I5Q76_RS12350	COG1953	Uracil, thiamine, allantoin
I5Q76_RS12390	COG0406	alpha-ribazole phosphatase activity
I5Q76_RS12405	COG2207	Transcriptional regulator
I5Q76_RS12420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I5Q76_RS12445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I5Q76_RS12490	COG0765	amino acid transport
I5Q76_RS12500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
I5Q76_RS12510	COG2070	2-Nitropropane dioxygenase
I5Q76_RS12515	COG0583	DNA-binding transcription factor activity
I5Q76_RS12525	COG1902	pentaerythritol trinitrate reductase activity
I5Q76_RS12530	COG4529	Protein conserved in bacteria
I5Q76_RS12535	COG0477	Major facilitator Superfamily
I5Q76_RS12565	COG2223	nitrite transmembrane transporter activity
I5Q76_RS12575	COG1609	Transcriptional regulator
I5Q76_RS12580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS12590	COG3037	sugar-specific permease SgaT UlaA
I5Q76_RS12595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I5Q76_RS12605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5Q76_RS12610	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
I5Q76_RS12610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5Q76_RS12610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5Q76_RS12625	COG0583	DNA-binding transcription factor activity
I5Q76_RS12630	COG0583	DNA-binding transcription factor activity
I5Q76_RS12635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5Q76_RS12645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I5Q76_RS12660	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS12670	COG1609	Transcriptional regulator
I5Q76_RS12700	COG1652	LysM domain
I5Q76_RS12725	COG0456	acetyltransferase
I5Q76_RS12725	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
I5Q76_RS12735	COG0667	Aldo Keto reductase
I5Q76_RS12740	COG0667	Aldo Keto reductase
I5Q76_RS12745	COG3386	PFAM SMP-30 Gluconolaconase
I5Q76_RS12750	COG0667	Aldo Keto reductase
I5Q76_RS12765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5Q76_RS12785	COG2723	6-phospho-beta-galactosidase activity
I5Q76_RS12805	COG4977	sequence-specific DNA binding
I5Q76_RS12825	COG4977	sequence-specific DNA binding
I5Q76_RS12830	COG1349	DNA-binding transcription factor activity
I5Q76_RS12835	COG1070	Carbohydrate kinase
I5Q76_RS12845	COG1349	DNA-binding transcription factor activity
I5Q76_RS12850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I5Q76_RS12855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5Q76_RS12860	COG0738	Major facilitator superfamily
I5Q76_RS12905	COG1929	Belongs to the glycerate kinase type-1 family
I5Q76_RS12910	COG3835	regulator
I5Q76_RS12930	COG2186	Transcriptional regulator
I5Q76_RS12935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5Q76_RS12935	COG1263	PTS System
I5Q76_RS12945	COG2814	Major facilitator Superfamily
I5Q76_RS12950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS12950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS12965	COG2819	hydrolase of the alpha beta superfamily
I5Q76_RS12970	COG3300	MHYT domain
I5Q76_RS12970	COG5001	Diguanylate cyclase
I5Q76_RS13005	COG3188	usher protein
I5Q76_RS13015	COG1649	PFAM Uncharacterised BCR, COG1649
I5Q76_RS13020	COG3550	peptidyl-serine autophosphorylation
I5Q76_RS13025	COG1396	sequence-specific DNA binding
I5Q76_RS13030	COG2351	hydroxyisourate hydrolase activity
I5Q76_RS13035	COG3195	allantoin biosynthetic process
I5Q76_RS13035	COG3648	Uricase
I5Q76_RS13040	COG2233	PERMEase
I5Q76_RS13070	COG2207	Transcriptional regulator
I5Q76_RS13085	COG4628	conserved protein (DUF2132)
I5Q76_RS13105	COG2011	ABC-type metal ion transport system permease component
I5Q76_RS13110	COG2070	2-Nitropropane dioxygenase
I5Q76_RS13120	COG0477	Major facilitator Superfamily
I5Q76_RS13190	COG2199	diguanylate cyclase activity
I5Q76_RS13205	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS13210	COG0583	DNA-binding transcription factor activity
I5Q76_RS13220	COG0039	L-malate dehydrogenase activity
I5Q76_RS13225	COG1349	DNA-binding transcription factor activity
I5Q76_RS13230	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
I5Q76_RS13235	COG3395	kinase activity
I5Q76_RS13245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
I5Q76_RS13250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I5Q76_RS13255	COG2271	Major facilitator Superfamily
I5Q76_RS13285	COG4977	sequence-specific DNA binding
I5Q76_RS13295	COG0697	spore germination
I5Q76_RS13300	COG2814	Major facilitator Superfamily
I5Q76_RS13335	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
I5Q76_RS13370	COG2223	nitrite transmembrane transporter activity
I5Q76_RS13375	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
I5Q76_RS13390	COG1349	DNA-binding transcription factor activity
I5Q76_RS13395	COG2084	Dehydrogenase
I5Q76_RS13400	COG3395	kinase activity
I5Q76_RS13405	COG0235	Class ii aldolase
I5Q76_RS13410	COG3622	Belongs to the hyi family
I5Q76_RS13415	COG2610	gluconate transmembrane transporter activity
I5Q76_RS13420	COG3708	Transcriptional regulator
I5Q76_RS13420	COG2207	Transcriptional regulator
I5Q76_RS13435	COG2200	EAL domain
I5Q76_RS13440	COG1546	Belongs to the CinA family
I5Q76_RS13445	COG0071	Belongs to the small heat shock protein (HSP20) family
I5Q76_RS13480	COG2135	peptidase activity
I5Q76_RS13485	COG2207	Transcriptional regulator
I5Q76_RS13500	COG4221	oxidoreductase activity
I5Q76_RS13505	COG1802	Transcriptional regulator
I5Q76_RS13510	COG0589	response to stress
I5Q76_RS13515	COG0246	Mannitol dehydrogenase
I5Q76_RS13520	COG2271	Major facilitator Superfamily
I5Q76_RS13535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I5Q76_RS13555	COG0243	molybdopterin cofactor binding
I5Q76_RS13560	COG0437	4 iron, 4 sulfur cluster binding
I5Q76_RS13565	COG3302	dmso reductase anchor subunit
I5Q76_RS13580	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
I5Q76_RS13585	COG1940	carbohydrate kinase activity
I5Q76_RS13590	COG0583	DNA-binding transcription factor activity
I5Q76_RS13595	COG2814	Major facilitator Superfamily
I5Q76_RS13600	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
I5Q76_RS13610	COG3591	Belongs to the peptidase S1B family
I5Q76_RS13630	COG0628	permease
I5Q76_RS13660	COG0679	Auxin Efflux Carrier
I5Q76_RS13670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I5Q76_RS13705	COG3290	protein histidine kinase activity
I5Q76_RS13710	COG4565	transcriptional regulatory protein
I5Q76_RS13730	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
I5Q76_RS13730	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
I5Q76_RS13740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I5Q76_RS13745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
I5Q76_RS13755	COG0183	Belongs to the thiolase family
I5Q76_RS13760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
I5Q76_RS13770	COG1414	Transcriptional regulator
I5Q76_RS13775	COG2840	Smr protein MutS2
I5Q76_RS13780	COG0583	DNA-binding transcription factor activity
I5Q76_RS13790	COG1473	amidohydrolase
I5Q76_RS13795	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
I5Q76_RS13810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I5Q76_RS13825	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
I5Q76_RS13830	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
I5Q76_RS13845	COG0531	amino acid
I5Q76_RS13855	COG3136	membrane protein required for alginate biosynthesis
I5Q76_RS13860	COG0745	RESPONSE REGULATOR receiver
I5Q76_RS13870	COG2205	protein histidine kinase activity
I5Q76_RS13880	COG0114	fumarate hydratase activity
I5Q76_RS13885	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
I5Q76_RS13885	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
I5Q76_RS13890	COG1482	cell wall glycoprotein biosynthetic process
I5Q76_RS13895	COG5339	Protein conserved in bacteria
I5Q76_RS13900	COG1609	Transcriptional regulator
I5Q76_RS13910	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
I5Q76_RS13935	COG2391	methyltransferase activity
I5Q76_RS13940	COG0425	Belongs to the sulfur carrier protein TusA family
I5Q76_RS13945	COG5562	phage envelope protein
I5Q76_RS13950	COG0401	homolog of Blt101
I5Q76_RS13955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I5Q76_RS13960	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS13970	COG1434	Gram-negative-bacterium-type cell wall biogenesis
I5Q76_RS13980	COG1113	amino acid transport
I5Q76_RS13985	COG2988	succinylglutamate desuccinylase activity
I5Q76_RS13990	COG3724	N-succinylarginine dihydrolase activity
I5Q76_RS13995	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS14000	COG3138	arginine N-succinyltransferase
I5Q76_RS14005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
I5Q76_RS14015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I5Q76_RS14020	COG0667	Aldo Keto reductase
I5Q76_RS14025	COG0583	DNA-binding transcription factor activity
I5Q76_RS14050	COG4122	O-methyltransferase activity
I5Q76_RS14055	COG1643	Atp-dependent helicase
I5Q76_RS14070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I5Q76_RS14075	COG3327	negative regulation of DNA-templated transcription, initiation
I5Q76_RS14080	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
I5Q76_RS14085	COG0183	Belongs to the thiolase family
I5Q76_RS14090	COG2050	protein possibly involved in aromatic compounds catabolism
I5Q76_RS14095	COG1250	3-hydroxyacyl-CoA dehydrogenase
I5Q76_RS14105	COG1024	Enoyl-CoA hydratase
I5Q76_RS14110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I5Q76_RS14115	COG2151	metal-sulfur cluster biosynthetic enzyme
I5Q76_RS14120	COG3396	Phenylacetate-CoA oxygenase
I5Q76_RS14125	COG3460	Phenylacetate-CoA oxygenase
I5Q76_RS14130	COG3396	Phenylacetate-CoA oxygenase
I5Q76_RS14135	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS14135	COG2030	dehydratase
I5Q76_RS14155	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS14160	COG2207	Transcriptional regulator
I5Q76_RS14165	COG3784	Protein of unknown function (DUF1318)
I5Q76_RS14175	COG2911	Protein conserved in bacteria
I5Q76_RS14180	COG0586	Pfam SNARE associated Golgi protein
I5Q76_RS14185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I5Q76_RS14190	COG3187	Heat shock protein
I5Q76_RS14195	COG3042	response to heat
I5Q76_RS14200	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
I5Q76_RS14200	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
I5Q76_RS14200	COG1013	pyruvate-flavodoxin oxidoreductase activity
I5Q76_RS14200	COG0674	pyruvate-flavodoxin oxidoreductase activity
I5Q76_RS14205	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
I5Q76_RS14215	COG0589	response to stress
I5Q76_RS14225	COG0513	Belongs to the DEAD box helicase family
I5Q76_RS14235	COG1349	DNA-binding transcription factor activity
I5Q76_RS14240	COG0673	inositol 2-dehydrogenase activity
I5Q76_RS14255	COG1113	amino acid transport
I5Q76_RS14260	COG1522	sequence-specific DNA binding
I5Q76_RS14270	COG1448	Aminotransferase
I5Q76_RS14275	COG2011	ABC-type metal ion transport system permease component
I5Q76_RS14290	COG0436	Aminotransferase
I5Q76_RS14295	COG0604	alcohol dehydrogenase
I5Q76_RS14325	COG0583	DNA-binding transcription factor activity
I5Q76_RS14345	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS14350	COG1309	transcriptional regulator
I5Q76_RS14355	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS14465	COG2885	chlorophyll binding
I5Q76_RS14490	COG0693	protein deglycase activity
I5Q76_RS14495	COG1078	dGTPase activity
I5Q76_RS14500	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS14505	COG0583	DNA-binding transcription factor activity
I5Q76_RS14525	COG0656	L-ascorbic acid biosynthetic process
I5Q76_RS14550	COG4166	transmembrane transport
I5Q76_RS14560	COG2866	Carboxypeptidase
I5Q76_RS14565	COG4948	Mandelate Racemase Muconate Lactonizing
I5Q76_RS14570	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
I5Q76_RS14575	COG3180	Ammonia monooxygenase
I5Q76_RS14585	COG1486	melibiose metabolic process
I5Q76_RS14590	COG0583	DNA-binding transcription factor activity
I5Q76_RS14600	COG3106	COG3106 Predicted ATPase
I5Q76_RS14610	COG1983	PspC domain protein
I5Q76_RS14620	COG1842	Phage shock protein A
I5Q76_RS14625	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
I5Q76_RS14635	COG1473	amidohydrolase
I5Q76_RS14650	COG0702	epimerase
I5Q76_RS14680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
I5Q76_RS14685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
I5Q76_RS14740	COG1196	nuclear chromosome segregation
I5Q76_RS14830	COG5484	DNA packaging
I5Q76_RS14830	COG3728	DNA packaging
I5Q76_RS14870	COG0484	heat shock protein binding
I5Q76_RS14875	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
I5Q76_RS14935	COG1846	Transcriptional regulator
I5Q76_RS14965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I5Q76_RS15000	COG4171	peptide transport system, permease
I5Q76_RS15015	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
I5Q76_RS15025	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
I5Q76_RS15030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I5Q76_RS15030	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I5Q76_RS15045	COG1349	DNA-binding transcription factor activity
I5Q76_RS15055	COG0023	Translation Initiation Factor
I5Q76_RS15065	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
I5Q76_RS15070	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
I5Q76_RS15075	COG0671	phosphoesterase, PA-phosphatase related
I5Q76_RS15085	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
I5Q76_RS15110	COG0616	signal peptide processing
I5Q76_RS15120	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS15125	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
I5Q76_RS15150	COG0583	DNA-binding transcription factor activity
I5Q76_RS15160	COG0009	L-threonylcarbamoyladenylate synthase
I5Q76_RS15170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
I5Q76_RS15175	COG0512	Glutamine amidotransferase of anthranilate synthase
I5Q76_RS15175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
I5Q76_RS15180	COG0135	phosphoribosylanthranilate isomerase activity
I5Q76_RS15180	COG0134	indole-3-glycerol-phosphate synthase activity
I5Q76_RS15215	COG4774	siderophore transport
I5Q76_RS15225	COG3047	cAMP biosynthetic process
I5Q76_RS15230	COG0727	PFAM Uncharacterised protein family (UPF0153)
I5Q76_RS15260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I5Q76_RS15265	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS15270	COG1988	membrane-bound metal-dependent
I5Q76_RS15275	COG1823	symporter activity
I5Q76_RS15285	COG0753	catalase activity
I5Q76_RS15295	COG1486	melibiose metabolic process
I5Q76_RS15300	COG2169	Transcriptional regulator
I5Q76_RS15300	COG1917	Cupin 2, conserved barrel domain protein
I5Q76_RS15305	COG1447	Phosphotransferase system cellobiose-specific component IIA
I5Q76_RS15310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5Q76_RS15320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5Q76_RS15325	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I5Q76_RS15335	COG0322	excinuclease ABC activity
I5Q76_RS15340	COG3678	ATP-independent chaperone mediated protein folding
I5Q76_RS15350	COG3724	N-succinylarginine dihydrolase activity
I5Q76_RS15360	COG3138	arginine N-succinyltransferase
I5Q76_RS15370	COG0708	Exodeoxyribonuclease III
I5Q76_RS15375	COG0398	Pfam SNARE associated Golgi protein
I5Q76_RS15380	COG0398	Pfam SNARE associated Golgi protein
I5Q76_RS15385	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I5Q76_RS15390	COG4134	Bacterial extracellular solute-binding protein
I5Q76_RS15395	COG4135	transport system, permease component
I5Q76_RS15400	COG4136	ATPase activity
I5Q76_RS15405	COG2897	thiosulfate sulfurtransferase activity
I5Q76_RS15410	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I5Q76_RS15415	COG0494	nUDIX hydrolase
I5Q76_RS15420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I5Q76_RS15425	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS15425	COG0604	alcohol dehydrogenase
I5Q76_RS15425	COG3321	synthase
I5Q76_RS15430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I5Q76_RS15435	COG0709	Synthesizes selenophosphate from selenide and ATP
I5Q76_RS15445	COG0778	Nitroreductase
I5Q76_RS15450	COG0616	signal peptide processing
I5Q76_RS15455	COG0252	asparaginase activity
I5Q76_RS15460	COG1335	isochorismatase
I5Q76_RS15475	COG3139	Protein of unknown function (DUF1315)
I5Q76_RS15495	COG0656	L-ascorbic acid biosynthetic process
I5Q76_RS15500	COG3713	MltA-interacting MipA family protein
I5Q76_RS15505	COG2766	serine protein kinase
I5Q76_RS15520	COG0386	Belongs to the glutathione peroxidase family
I5Q76_RS15545	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS15550	COG0583	DNA-binding transcription factor activity
I5Q76_RS15555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
I5Q76_RS15560	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
I5Q76_RS15565	COG3344	reverse transcriptase
I5Q76_RS15575	COG0859	PFAM glycosyl transferase family 9
I5Q76_RS15580	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I5Q76_RS15590	COG2207	Transcriptional regulator
I5Q76_RS15595	COG2807	transmembrane transport
I5Q76_RS15600	COG0504	CTP synthase activity
I5Q76_RS15605	COG1683	Conserved Protein
I5Q76_RS15610	COG3189	MarR family transcriptional regulator
I5Q76_RS15615	COG3042	response to heat
I5Q76_RS15620	COG2199	diguanylate cyclase activity
I5Q76_RS15620	COG2203	Gaf domain
I5Q76_RS15640	COG3182	Iron-regulated membrane protein
I5Q76_RS15650	COG1560	Kdo2-lipid A biosynthetic process
I5Q76_RS15660	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
I5Q76_RS15665	COG3706	GGDEF domain
I5Q76_RS15670	COG0583	DNA-binding transcription factor activity
I5Q76_RS15675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
I5Q76_RS15705	COG1294	oxidase, subunit
I5Q76_RS15710	COG1271	oxidase subunit
I5Q76_RS15715	COG3546	catalase activity
I5Q76_RS15720	COG3685	Protein conserved in bacteria
I5Q76_RS15725	COG3685	Protein conserved in bacteria
I5Q76_RS15730	COG3729	General stress protein
I5Q76_RS15735	COG1063	alcohol dehydrogenase
I5Q76_RS15740	COG3813	Protein conserved in bacteria
I5Q76_RS15760	COG0640	Transcriptional regulator
I5Q76_RS15765	COG0538	isocitrate dehydrogenase activity
I5Q76_RS15770	COG1187	pseudouridine synthase activity
I5Q76_RS15790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
I5Q76_RS15810	COG2205	protein histidine kinase activity
I5Q76_RS15815	COG2850	peptidyl-arginine hydroxylation
I5Q76_RS15835	COG1177	transmembrane transport
I5Q76_RS15850	COG0318	PFAM AMP-dependent synthetase and ligase
I5Q76_RS15855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
I5Q76_RS15860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
I5Q76_RS15865	COG0698	ribose 5-phosphate isomerase
I5Q76_RS15880	COG3395	kinase activity
I5Q76_RS15895	COG2390	Transcriptional regulator
I5Q76_RS15905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
I5Q76_RS15915	COG4591	ABC-type transport system involved in lipoprotein release permease component
I5Q76_RS15925	COG4591	ABC-type transport system involved in lipoprotein release permease component
I5Q76_RS15940	COG1376	ErfK ybiS ycfS ynhG family protein
I5Q76_RS15940	COG1388	LysM domain
I5Q76_RS15955	COG1309	transcriptional regulator
I5Q76_RS15970	COG3134	Outer membrane lipoprotein
I5Q76_RS15975	COG1252	NADH dehydrogenase
I5Q76_RS16000	COG5633	Lipoprotein
I5Q76_RS16005	COG0537	adenosine 5'-monophosphoramidase activity
I5Q76_RS16015	COG0084	hydrolase, TatD family'
I5Q76_RS16020	COG0470	DNA polymerase III
I5Q76_RS16030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I5Q76_RS16035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I5Q76_RS16040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I5Q76_RS16055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I5Q76_RS16075	COG1399	metal-binding, possibly nucleic acid-binding protein
I5Q76_RS16095	COG1530	ribonuclease E activity
I5Q76_RS16100	COG0583	DNA-binding transcription factor activity
I5Q76_RS16105	COG2814	Major facilitator Superfamily
I5Q76_RS16125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I5Q76_RS16170	COG1560	Kdo2-lipid A biosynthetic process
I5Q76_RS16185	COG5645	(Lipo)protein
I5Q76_RS16220	COG3381	protein complex oligomerization
I5Q76_RS16250	COG1309	transcriptional regulator
I5Q76_RS16255	COG0583	DNA-binding transcription factor activity
I5Q76_RS16265	COG1335	isochorismatase
I5Q76_RS16280	COG1702	phosphate starvation-inducible protein PhoH
I5Q76_RS16300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I5Q76_RS16310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I5Q76_RS16325	COG1309	transcriptional regulator
I5Q76_RS16360	COG2233	PERMEase
I5Q76_RS16370	COG3729	General stress protein
I5Q76_RS16400	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS16415	COG0531	amino acid
I5Q76_RS16420	COG0174	glutamine synthetase
I5Q76_RS16425	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
I5Q76_RS16430	COG1396	sequence-specific DNA binding
I5Q76_RS16430	COG1917	Cupin 2, conserved barrel domain protein
I5Q76_RS16435	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS16440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5Q76_RS16445	COG0583	DNA-binding transcription factor activity
I5Q76_RS16450	COG0473	3-isopropylmalate dehydrogenase activity
I5Q76_RS16455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I5Q76_RS16460	COG4638	Rieske (2fe-2S)
I5Q76_RS16465	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS16470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I5Q76_RS16495	COG0670	Belongs to the BI1 family
I5Q76_RS16510	COG2207	Transcriptional regulator
I5Q76_RS16515	COG1881	PFAM PEBP family protein
I5Q76_RS16530	COG1832	CoA-binding protein
I5Q76_RS16540	COG0210	DNA helicase
I5Q76_RS16545	COG3304	Inner membrane component domain
I5Q76_RS16550	COG1289	transmembrane transporter activity
I5Q76_RS16555	COG3070	regulator of competence-specific genes
I5Q76_RS16575	COG1067	ATP-dependent peptidase activity
I5Q76_RS16585	COG3130	regulation of translation
I5Q76_RS16590	COG3009	Protein conserved in bacteria
I5Q76_RS16595	COG3008	intermembrane lipid transfer
I5Q76_RS16595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
I5Q76_RS16600	COG2995	paraquat-inducible protein a
I5Q76_RS16605	COG0488	(ABC) transporter
I5Q76_RS16615	COG0633	Ferredoxin
I5Q76_RS16615	COG3217	Mosc domain protein beta barrel domain protein
I5Q76_RS16630	COG0431	NADPH-dependent FMN reductase
I5Q76_RS16635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5Q76_RS16640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5Q76_RS16645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5Q76_RS16655	COG0308	aminopeptidase N
I5Q76_RS16665	COG1473	amidohydrolase
I5Q76_RS16675	COG0814	amino acid
I5Q76_RS16695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
I5Q76_RS16700	COG1448	Aminotransferase
I5Q76_RS16705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5Q76_RS16710	COG3108	Peptidase M15
I5Q76_RS16715	COG2989	Protein conserved in bacteria
I5Q76_RS16725	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
I5Q76_RS16735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I5Q76_RS16740	COG1434	Gram-negative-bacterium-type cell wall biogenesis
I5Q76_RS16745	COG3173	Aminoglycoside phosphotransferase
I5Q76_RS16760	COG3214	Protein conserved in bacteria
I5Q76_RS16775	COG0658	competence protein
I5Q76_RS16775	COG2333	competence protein COMEC
I5Q76_RS16785	COG0539	negative regulation of cytoplasmic translation
I5Q76_RS16805	COG2323	membrane
I5Q76_RS16810	COG1944	ATP diphosphatase activity
I5Q76_RS16815	COG2116	formate transmembrane transporter activity
I5Q76_RS16820	COG1882	Formate acetyltransferase
I5Q76_RS16825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I5Q76_RS16830	COG0477	Major facilitator Superfamily
I5Q76_RS16835	COG3302	dmso reductase anchor subunit
I5Q76_RS16840	COG0437	4 iron, 4 sulfur cluster binding
I5Q76_RS16845	COG0243	molybdopterin cofactor binding
I5Q76_RS16855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
I5Q76_RS16865	COG1674	ftsk spoiiie
I5Q76_RS16865	COG1178	ABC-type Fe3 transport system permease component
I5Q76_RS16875	COG0492	ferredoxin-NADP+ reductase activity
I5Q76_RS16880	COG4988	ABC transporter
I5Q76_RS16885	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
I5Q76_RS16900	COG0542	response to heat
I5Q76_RS16910	COG1278	Cold shock
I5Q76_RS16920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5Q76_RS16925	COG3593	DNA synthesis involved in DNA repair
I5Q76_RS16935	COG2431	L-lysine efflux transmembrane transporter activity
I5Q76_RS16945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I5Q76_RS16955	COG0028	Belongs to the TPP enzyme family
I5Q76_RS16960	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
I5Q76_RS16965	COG0702	epimerase
I5Q76_RS16970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I5Q76_RS16975	COG3023	N-Acetylmuramoyl-L-alanine amidase
I5Q76_RS16980	COG4251	negative regulation of phosphorylation
I5Q76_RS16980	COG2203	Gaf domain
I5Q76_RS16980	COG3706	GGDEF domain
I5Q76_RS16980	COG5001	Diguanylate cyclase
I5Q76_RS16990	COG1126	abc transporter atp-binding protein
I5Q76_RS16995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5Q76_RS17000	COG4215	(ABC) transporter
I5Q76_RS17005	COG4160	amino acid transport
I5Q76_RS17010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5Q76_RS17015	COG5002	protein histidine kinase activity
I5Q76_RS17020	COG0745	RESPONSE REGULATOR receiver
I5Q76_RS17035	COG1177	transmembrane transport
I5Q76_RS17040	COG1176	ABC-type spermidine putrescine transport system, permease component I
I5Q76_RS17045	COG3842	ATPase activity
I5Q76_RS17050	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
I5Q76_RS17065	COG0778	Nitroreductase
I5Q76_RS17225	COG4695	Portal protein
I5Q76_RS17265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I5Q76_RS17300	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
I5Q76_RS17310	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
I5Q76_RS17315	COG3226	Transcriptional regulator
I5Q76_RS17320	COG0738	Major facilitator superfamily
I5Q76_RS17325	COG0561	phosphatase activity
I5Q76_RS17330	COG2814	Major facilitator Superfamily
I5Q76_RS17335	COG0671	phosphoesterase, PA-phosphatase related
I5Q76_RS17340	COG1349	DNA-binding transcription factor activity
I5Q76_RS17345	COG1686	Belongs to the peptidase S11 family
I5Q76_RS17355	COG0625	glutathione transferase activity
I5Q76_RS17360	COG2133	pyrroloquinoline quinone binding
I5Q76_RS17370	COG2223	nitrite transmembrane transporter activity
I5Q76_RS17390	COG0747	negative chemotaxis
I5Q76_RS17405	COG0303	'Molybdopterin
I5Q76_RS17410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I5Q76_RS17415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I5Q76_RS17420	COG1882	Formate acetyltransferase
I5Q76_RS17425	COG0561	phosphatase activity
I5Q76_RS17435	COG1609	Transcriptional regulator
I5Q76_RS17440	COG2271	Major facilitator Superfamily
I5Q76_RS17450	COG0488	(ABC) transporter
I5Q76_RS17455	COG2365	Tyrosine phosphatase family
I5Q76_RS17460	COG1376	ErfK ybiS ycfS ynhG family protein
I5Q76_RS17465	COG2188	Transcriptional regulator
I5Q76_RS17470	COG2723	6-phospho-beta-galactosidase activity
I5Q76_RS17475	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I5Q76_RS17490	COG2194	sulfuric ester hydrolase activity
I5Q76_RS17495	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
I5Q76_RS17510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5Q76_RS17515	COG0765	amino acid transport
I5Q76_RS17520	COG1126	abc transporter atp-binding protein
I5Q76_RS17525	COG0668	transmembrane transport
I5Q76_RS17535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I5Q76_RS17545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I5Q76_RS17555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
I5Q76_RS17560	COG1199	ATP-dependent helicase activity
I5Q76_RS17565	COG0513	Belongs to the DEAD box helicase family
I5Q76_RS17570	COG3958	Transketolase
I5Q76_RS17575	COG3959	Transketolase, thiamine diphosphate binding domain
I5Q76_RS17580	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS17585	COG2271	Major facilitator Superfamily
I5Q76_RS17595	COG0583	DNA-binding transcription factor activity
I5Q76_RS17600	COG1309	transcriptional regulator
I5Q76_RS17605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5Q76_RS17610	COG1131	(ABC) transporter
I5Q76_RS17615	COG0842	Transport permease protein
I5Q76_RS17620	COG0842	Transport permease protein
I5Q76_RS17630	COG3568	Endonuclease Exonuclease Phosphatase
I5Q76_RS17635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I5Q76_RS17640	COG0392	lysyltransferase activity
I5Q76_RS17645	COG0670	Belongs to the BI1 family
I5Q76_RS17650	COG0314	molybdopterin synthase activity
I5Q76_RS17655	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
I5Q76_RS17665	COG0521	Mo-molybdopterin cofactor biosynthetic process
I5Q76_RS17685	COG0745	RESPONSE REGULATOR receiver
I5Q76_RS17690	COG0642	Histidine kinase
I5Q76_RS17715	COG2226	methyltransferase
I5Q76_RS17730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I5Q76_RS17735	COG1881	PFAM PEBP family protein
I5Q76_RS17775	COG4677	pectinesterase activity
I5Q76_RS17785	COG0589	response to stress
I5Q76_RS17790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5Q76_RS17825	COG0789	Transcriptional regulator
I5Q76_RS17830	COG2200	EAL domain
I5Q76_RS17855	COG0561	phosphatase activity
I5Q76_RS17865	COG4149	molybdate abc transporter
I5Q76_RS17870	COG0725	ABC transporter, periplasmic molybdate-binding protein
I5Q76_RS17880	COG2005	Transcriptional regulator
I5Q76_RS17880	COG3585	molybdate ion transport
I5Q76_RS17885	COG1119	ATPase activity
I5Q76_RS17895	COG1085	galactose-1-phosphate uridylyltransferase
I5Q76_RS17905	COG2017	converts alpha-aldose to the beta-anomer
I5Q76_RS17935	COG0471	metal ion transport
I5Q76_RS17935	COG0490	domain, Protein
I5Q76_RS17940	COG0583	DNA-binding transcription factor activity
I5Q76_RS17955	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
I5Q76_RS17955	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
I5Q76_RS17960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
I5Q76_RS17975	COG3201	nicotinamide mononucleotide transporter
I5Q76_RS17980	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
I5Q76_RS18025	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
I5Q76_RS18030	COG2885	chlorophyll binding
I5Q76_RS18040	COG3064	Membrane
I5Q76_RS18045	COG0848	biopolymer transport protein
I5Q76_RS18050	COG0811	peptide transport
I5Q76_RS18055	COG0824	Thioesterase
I5Q76_RS18060	COG3790	cyd operon protein YbgE
I5Q76_RS18065	COG4890	Cyd operon protein YbgT
I5Q76_RS18070	COG1294	oxidase, subunit
I5Q76_RS18075	COG1271	oxidase subunit
I5Q76_RS18080	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I5Q76_RS18090	COG0508	dehydrogenase complex catalyzes the overall conversion of
I5Q76_RS18095	COG0567	Dehydrogenase, E1 component
I5Q76_RS18100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
I5Q76_RS18105	COG1053	succinate dehydrogenase
I5Q76_RS18110	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
I5Q76_RS18115	COG2009	succinate dehydrogenase
I5Q76_RS18150	COG1984	allophanate hydrolase subunit 2
I5Q76_RS18155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
I5Q76_RS18170	COG0415	Belongs to the DNA photolyase family
I5Q76_RS18200	COG2205	protein histidine kinase activity
I5Q76_RS18205	COG0745	RESPONSE REGULATOR receiver
I5Q76_RS18215	COG0033	Phosphoglucomutase
I5Q76_RS18225	COG0596	Alpha beta hydrolase
I5Q76_RS18240	COG0735	belongs to the Fur family
I5Q76_RS18280	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I5Q76_RS18285	COG1846	Transcriptional regulator
I5Q76_RS18285	COG1940	carbohydrate kinase activity
I5Q76_RS18290	COG0647	UMP catabolic process
I5Q76_RS18295	COG0367	asparagine synthase
I5Q76_RS18335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I5Q76_RS18345	COG1702	phosphate starvation-inducible protein PhoH
I5Q76_RS18355	COG4535	Mg2 and Co2 transporter CorC
I5Q76_RS18370	COG0765	amino acid transport
I5Q76_RS18375	COG0765	amino acid transport
I5Q76_RS18380	COG1126	abc transporter atp-binding protein
I5Q76_RS18395	COG2888	peptidyl-tyrosine sulfation
I5Q76_RS18410	COG1466	dna polymerase III delta subunit
I5Q76_RS18425	COG0799	negative regulation of ribosome biogenesis
I5Q76_RS18435	COG0768	penicillin binding
I5Q76_RS18440	COG0772	Belongs to the SEDS family
I5Q76_RS18445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
I5Q76_RS18450	COG1686	Belongs to the peptidase S11 family
I5Q76_RS18465	COG0583	DNA-binding transcription factor activity
I5Q76_RS18480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I5Q76_RS18500	COG3069	C4-dicarboxylate transmembrane transporter activity
I5Q76_RS18505	COG3719	Belongs to the RNase T2 family
I5Q76_RS18510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
I5Q76_RS18530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I5Q76_RS18535	COG0583	DNA-binding transcription factor activity
I5Q76_RS18540	COG3969	phosphoadenosine phosphosulfate
I5Q76_RS18545	COG1475	DNA binding
I5Q76_RS18550	COG0436	Aminotransferase
I5Q76_RS18580	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS18585	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS18595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I5Q76_RS18610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
I5Q76_RS18620	COG0402	S-adenosylhomocysteine deaminase activity
I5Q76_RS18630	COG0483	inositol monophosphate 1-phosphatase activity
I5Q76_RS18635	COG2271	Major facilitator Superfamily
I5Q76_RS18665	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS18670	COG1129	ABC transporter
I5Q76_RS18675	COG0371	Dehydrogenase
I5Q76_RS18680	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS18695	COG2879	small protein
I5Q76_RS18700	COG1966	Carbon starvation protein
I5Q76_RS18710	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS18715	COG1535	isochorismatase
I5Q76_RS18715	COG3433	isochorismatase activity
I5Q76_RS18720	COG1021	2,3-dihydroxybenzoate-AMP ligase
I5Q76_RS18725	COG1169	isochorismate synthase
I5Q76_RS18730	COG4592	Periplasmic binding protein
I5Q76_RS18740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5Q76_RS18745	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5Q76_RS18750	COG1120	ATPase activity
I5Q76_RS18755	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
I5Q76_RS18755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5Q76_RS18760	COG3251	PFAM MbtH domain protein
I5Q76_RS18765	COG2382	esterase
I5Q76_RS18770	COG4771	TonB-dependent receptor
I5Q76_RS18775	COG2977	Belongs to the P-Pant transferase superfamily
I5Q76_RS18780	COG3958	Transketolase
I5Q76_RS18785	COG3959	Transketolase, thiamine diphosphate binding domain
I5Q76_RS18790	COG2390	Transcriptional regulator
I5Q76_RS18795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
I5Q76_RS18800	COG1879	ABC-type sugar transport system periplasmic component
I5Q76_RS18810	COG1129	ABC transporter
I5Q76_RS18815	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS18825	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS18835	COG0583	DNA-binding transcription factor activity
I5Q76_RS18840	COG0668	transmembrane transport
I5Q76_RS18850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I5Q76_RS18875	COG0747	negative chemotaxis
I5Q76_RS18880	COG0601	transmembrane transport
I5Q76_RS18885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I5Q76_RS18890	COG0444	Belongs to the ABC transporter superfamily
I5Q76_RS18895	COG4608	Belongs to the ABC transporter superfamily
I5Q76_RS18905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I5Q76_RS18910	COG4221	oxidoreductase activity
I5Q76_RS18920	COG4215	(ABC) transporter
I5Q76_RS18925	COG0765	amino acid transport
I5Q76_RS18930	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
I5Q76_RS18945	COG0697	spore germination
I5Q76_RS18955	COG3698	Phosphodiester glycosidase
I5Q76_RS18995	COG2315	Protein conserved in bacteria
I5Q76_RS19000	COG0778	Nitroreductase
I5Q76_RS19010	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5Q76_RS19020	COG3716	PTS system mannose fructose sorbose family IID component
I5Q76_RS19025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
I5Q76_RS19030	COG2222	sugar isomerase
I5Q76_RS19035	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
I5Q76_RS19035	COG3933	PFAM sigma-54 factor interaction domain-containing protein
I5Q76_RS19050	COG0477	Major facilitator Superfamily
I5Q76_RS19055	COG0668	transmembrane transport
I5Q76_RS19085	COG3188	usher protein
I5Q76_RS19100	COG2771	luxR family
I5Q76_RS19110	COG0673	inositol 2-dehydrogenase activity
I5Q76_RS19120	COG2211	Major facilitator Superfamily
I5Q76_RS19125	COG1113	amino acid transport
I5Q76_RS19140	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS19145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5Q76_RS19155	COG0531	amino acid
I5Q76_RS19170	COG4680	protein conserved in bacteria
I5Q76_RS19210	COG0667	Aldo Keto reductase
I5Q76_RS19215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5Q76_RS19220	COG1473	amidohydrolase
I5Q76_RS19250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5Q76_RS19255	COG1120	ATPase activity
I5Q76_RS19260	COG1566	PFAM secretion protein HlyD family protein
I5Q76_RS19305	COG4211	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS19310	COG1129	ABC transporter
I5Q76_RS19325	COG0673	inositol 2-dehydrogenase activity
I5Q76_RS19355	COG3104	oligopeptide transport
I5Q76_RS19360	COG1982	Orn Lys Arg decarboxylase major
I5Q76_RS19365	COG0531	amino acid
I5Q76_RS19370	COG3710	Transcriptional regulator
I5Q76_RS19380	COG1560	Kdo2-lipid A biosynthetic process
I5Q76_RS19395	COG3188	usher protein
I5Q76_RS19400	COG3121	Chaperone
I5Q76_RS19405	COG3539	Fimbrial protein
I5Q76_RS19455	COG3344	reverse transcriptase
I5Q76_RS19595	COG3567	Phage-associated protein, HI1409 family
I5Q76_RS19600	COG1783	phage Terminase large subunit
I5Q76_RS19615	COG3772	lysozyme
I5Q76_RS19625	COG0484	heat shock protein binding
I5Q76_RS19685	COG0305	Participates in initiation and elongation during chromosome replication
I5Q76_RS19785	COG2501	S4 domain
I5Q76_RS19795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I5Q76_RS19810	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
I5Q76_RS19815	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
I5Q76_RS19835	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
I5Q76_RS19840	COG4181	ATPase activity
I5Q76_RS19845	COG2755	lipolytic protein G-D-S-L family
I5Q76_RS19850	COG0300	oxidoreductase activity
I5Q76_RS19855	COG3118	belongs to the thioredoxin family
I5Q76_RS19860	COG0390	transport system, permease component
I5Q76_RS19865	COG4619	ABC transporter
I5Q76_RS19870	COG0330	HflC and HflK could
I5Q76_RS19875	COG1585	Membrane protein implicated in regulation of membrane protease activity
I5Q76_RS19890	COG3735	TraB family
I5Q76_RS19895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I5Q76_RS19905	COG2223	nitrite transmembrane transporter activity
I5Q76_RS19910	COG4651	solute:proton antiporter activity
I5Q76_RS19910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
I5Q76_RS19915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5Q76_RS19955	COG2832	Protein of unknown function (DUF454)
I5Q76_RS19960	COG3923	Primosomal replication protein n
I5Q76_RS19970	COG5464	transposase or invertase
I5Q76_RS19975	COG3264	Mechanosensitive ion channel
I5Q76_RS19975	COG1196	nuclear chromosome segregation
I5Q76_RS19980	COG1309	transcriptional regulator
I5Q76_RS19985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5Q76_RS19990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5Q76_RS20005	COG0110	maltose O-acetyltransferase activity
I5Q76_RS20055	COG1874	Beta-galactosidase
I5Q76_RS20060	COG3867	Arabinogalactan endo-beta-1,4-galactanase
I5Q76_RS20065	COG3833	ABC-type maltose transport systems, permease component
I5Q76_RS20070	COG1175	transmembrane transport
I5Q76_RS20075	COG2182	Extracellular solute-binding protein
I5Q76_RS20085	COG4943	cyclic-guanylate-specific phosphodiesterase activity
I5Q76_RS20100	COG2364	Membrane
I5Q76_RS20130	COG3695	enzyme binding
I5Q76_RS20135	COG3126	Type III secretion system lipoprotein chaperone (YscW)
I5Q76_RS20140	COG1946	Acyl-CoA thioesterase
I5Q76_RS20145	COG0004	ammonium transporteR
I5Q76_RS20150	COG0347	Belongs to the P(II) protein family
I5Q76_RS20155	COG1132	(ABC) transporter
I5Q76_RS20160	COG1132	(ABC) transporter
I5Q76_RS20165	COG1522	sequence-specific DNA binding
I5Q76_RS20180	COG4533	DNA binding
I5Q76_RS20190	COG0824	Thioesterase
I5Q76_RS20195	COG1555	photosystem II stabilization
I5Q76_RS20200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I5Q76_RS20205	COG0776	regulation of translation
I5Q76_RS20210	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
I5Q76_RS20230	COG0271	Belongs to the BolA IbaG family
I5Q76_RS20235	COG3056	Lipoprotein
I5Q76_RS20240	COG2223	nitrite transmembrane transporter activity
I5Q76_RS20245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I5Q76_RS20255	COG1845	cytochrome c oxidase, subunit III
I5Q76_RS20260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
I5Q76_RS20275	COG1414	Transcriptional regulator
I5Q76_RS20280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
I5Q76_RS20285	COG1053	succinate dehydrogenase
I5Q76_RS20295	COG1053	succinate dehydrogenase
I5Q76_RS20310	COG0673	inositol 2-dehydrogenase activity
I5Q76_RS20315	COG2814	Major facilitator Superfamily
I5Q76_RS20325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
I5Q76_RS20330	COG0693	protein deglycase activity
I5Q76_RS20350	COG0142	geranyltranstransferase activity
I5Q76_RS20360	COG0667	Aldo Keto reductase
I5Q76_RS20365	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I5Q76_RS20385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I5Q76_RS20385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I5Q76_RS20395	COG4238	major outer membrane lipoprotein
I5Q76_RS20415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I5Q76_RS20420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I5Q76_RS20425	COG1862	Preprotein translocase
I5Q76_RS20450	COG0450	alkyl hydroperoxide reductase
I5Q76_RS20455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS20470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5Q76_RS20480	COG1228	amidohydrolase
I5Q76_RS20490	COG1335	isochorismatase
I5Q76_RS20495	COG0583	DNA-binding transcription factor activity
I5Q76_RS20500	COG0366	Alpha amylase catalytic
I5Q76_RS20525	COG0420	3'-5' exonuclease activity
I5Q76_RS20530	COG0419	ATPase involved in DNA repair
I5Q76_RS20535	COG1940	carbohydrate kinase activity
I5Q76_RS20550	COG4126	flavin adenine dinucleotide binding
I5Q76_RS20560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
I5Q76_RS20565	COG3416	Protein conserved in bacteria
I5Q76_RS20575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I5Q76_RS20585	COG1785	Belongs to the alkaline phosphatase family
I5Q76_RS20625	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
I5Q76_RS20630	COG1335	isochorismatase
I5Q76_RS20635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I5Q76_RS20640	COG0113	porphobilinogen synthase activity
I5Q76_RS20650	COG2175	clavaminate synthase activity
I5Q76_RS20655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5Q76_RS20660	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
I5Q76_RS20665	COG4521	taurine ABC transporter
I5Q76_RS20670	COG2040	homocysteine
I5Q76_RS20675	COG0833	amino acid
I5Q76_RS20690	COG4303	Ethanolamine ammonia lyase large subunit
I5Q76_RS20695	COG4302	ethanolamine ammonia-lyase activity
I5Q76_RS20735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5Q76_RS20740	COG1126	abc transporter atp-binding protein
I5Q76_RS20745	COG4597	amino acid ABC transporter
I5Q76_RS20750	COG0765	amino acid transport
I5Q76_RS20765	COG3188	usher protein
I5Q76_RS20790	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
I5Q76_RS20800	COG3639	organic phosphonate transmembrane transporter activity
I5Q76_RS20820	COG0791	NLP P60 protein
I5Q76_RS20850	COG2814	Major facilitator Superfamily
I5Q76_RS20855	COG3711	transcriptional antiterminator
I5Q76_RS20860	COG2190	(PTS) system
I5Q76_RS20860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5Q76_RS20860	COG1263	PTS System
I5Q76_RS20870	COG0673	inositol 2-dehydrogenase activity
I5Q76_RS20875	COG0673	inositol 2-dehydrogenase activity
I5Q76_RS20880	COG0583	DNA-binding transcription factor activity
I5Q76_RS20885	COG1408	metallophosphoesterase
I5Q76_RS20890	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS20900	COG4221	oxidoreductase activity
I5Q76_RS20910	COG0765	amino acid transport
I5Q76_RS20920	COG4221	oxidoreductase activity
I5Q76_RS20935	COG0436	Aminotransferase
I5Q76_RS20940	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
I5Q76_RS20945	COG1984	allophanate hydrolase subunit 2
I5Q76_RS20960	COG0697	spore germination
I5Q76_RS20965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I5Q76_RS20970	COG0439	Biotin carboxylase
I5Q76_RS20975	COG0511	ligase activity, forming carbon-carbon bonds
I5Q76_RS20985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
I5Q76_RS20990	COG0022	dehydrogenase e1 component
I5Q76_RS20995	COG0508	dehydrogenase complex catalyzes the overall conversion of
I5Q76_RS21000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I5Q76_RS21020	COG1070	Carbohydrate kinase
I5Q76_RS21025	COG1028	Short-chain dehydrogenase reductase Sdr
I5Q76_RS21030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I5Q76_RS21035	COG3775	system Galactitol-specific IIC component
I5Q76_RS21040	COG0625	glutathione transferase activity
I5Q76_RS21045	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
I5Q76_RS21060	COG0579	oxidoreductase
I5Q76_RS21065	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS21070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
I5Q76_RS21075	COG1113	amino acid transport
I5Q76_RS21080	COG1802	Transcriptional regulator
I5Q76_RS21100	COG2195	Cleaves the N-terminal amino acid of tripeptides
I5Q76_RS21105	COG0454	-acetyltransferase
I5Q76_RS21120	COG2991	Protein conserved in bacteria
I5Q76_RS21135	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
I5Q76_RS21140	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
I5Q76_RS21155	COG3034	peptidoglycan biosynthetic process
I5Q76_RS21160	COG0121	glutamine amidotransferase
I5Q76_RS21170	COG1960	acyl-CoA dehydrogenase activity
I5Q76_RS21175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I5Q76_RS21185	COG0583	DNA-binding transcription factor activity
I5Q76_RS21195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I5Q76_RS21205	COG2226	methyltransferase
I5Q76_RS21215	COG1388	LysM domain
I5Q76_RS21215	COG0741	lytic transglycosylase activity
I5Q76_RS21220	COG2226	methyltransferase
I5Q76_RS21230	COG2814	Major facilitator Superfamily
I5Q76_RS21235	COG0583	DNA-binding transcription factor activity
I5Q76_RS21240	COG0656	L-ascorbic acid biosynthetic process
I5Q76_RS21275	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
I5Q76_RS21285	COG2011	ABC-type metal ion transport system permease component
I5Q76_RS21290	COG1464	Belongs to the NlpA lipoprotein family
I5Q76_RS21300	COG1720	tRNA m6t6A37 methyltransferase activity
I5Q76_RS21310	COG0791	NLP P60 protein
I5Q76_RS21315	COG3015	lipoprotein NlpE involved in copper resistance
I5Q76_RS21320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
I5Q76_RS21335	COG4568	rho-dependent transcription termination
I5Q76_RS21345	COG0346	lactoylglutathione lyase activity
I5Q76_RS21350	COG1982	Orn Lys Arg decarboxylase major
I5Q76_RS21360	COG0587	DNA-directed DNA polymerase activity
I5Q76_RS21390	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
I5Q76_RS21400	COG0750	zinc metalloprotease
I5Q76_RS21405	COG0575	Belongs to the CDS family
I5Q76_RS21415	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
I5Q76_RS21440	COG0024	Methionine aminopeptidase
I5Q76_RS21445	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
I5Q76_RS21460	COG3835	regulator
I5Q76_RS21465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I5Q76_RS21485	COG2860	membrane
I5Q76_RS21505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5Q76_RS21510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I5Q76_RS21515	COG1120	ATPase activity
I5Q76_RS21520	COG4774	siderophore transport
I5Q76_RS21525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I5Q76_RS21615	COG1643	Atp-dependent helicase
I5Q76_RS21620	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
I5Q76_RS21640	COG0617	tRNA 3'-terminal CCA addition
I5Q76_RS21645	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
I5Q76_RS21665	COG0726	polysaccharide deacetylase
I5Q76_RS21670	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS21675	COG0842	Transport permease protein
I5Q76_RS21680	COG1131	(ABC) transporter
I5Q76_RS21685	COG0288	reversible hydration of carbon dioxide
I5Q76_RS21700	COG4993	Dehydrogenase
I5Q76_RS21705	COG2132	Multicopper oxidase
I5Q76_RS21750	COG3064	Membrane
I5Q76_RS21765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I5Q76_RS21770	COG0508	dehydrogenase complex catalyzes the overall conversion of
I5Q76_RS21775	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
I5Q76_RS21780	COG2186	Transcriptional regulator
I5Q76_RS21785	COG1113	amino acid transport
I5Q76_RS21790	COG2211	Major facilitator Superfamily
I5Q76_RS21795	COG3940	Belongs to the glycosyl hydrolase 43 family
I5Q76_RS21800	COG3725	Membrane protein required for beta-lactamase induction
I5Q76_RS21815	COG4969	Belongs to the N-Me-Phe pilin family
I5Q76_RS21820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I5Q76_RS21825	COG1459	type II secretion system
I5Q76_RS21850	COG0494	nUDIX hydrolase
I5Q76_RS21870	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
I5Q76_RS21875	COG0849	cell division
I5Q76_RS21900	COG0772	Belongs to the SEDS family
I5Q76_RS21915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I5Q76_RS21920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
I5Q76_RS21925	COG0768	penicillin binding
I5Q76_RS21945	COG1609	Transcriptional regulator
I5Q76_RS21955	COG0028	Belongs to the TPP enzyme family
I5Q76_RS22000	COG0738	Major facilitator superfamily
I5Q76_RS22010	COG0583	DNA-binding transcription factor activity
I5Q76_RS22015	COG2271	Major facilitator Superfamily
I5Q76_RS22020	COG2814	Major facilitator Superfamily
I5Q76_RS22040	COG1178	ABC-type Fe3 transport system permease component
I5Q76_RS22050	COG0586	Pfam SNARE associated Golgi protein
I5Q76_RS22070	COG0235	Class ii aldolase
I5Q76_RS22075	COG0417	DNA replication proofreading
I5Q76_RS22085	COG0564	pseudouridine synthase activity
I5Q76_RS22095	COG3493	citrate carrier protein
I5Q76_RS22110	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
I5Q76_RS22115	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
I5Q76_RS22125	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
I5Q76_RS22170	COG0505	Belongs to the CarA family
I5Q76_RS22180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
I5Q76_RS22205	COG1047	Peptidyl-prolyl cis-trans
I5Q76_RS22220	COG0196	riboflavin kinase activity
I5Q76_RS22230	COG0583	DNA-binding transcription factor activity
I5Q76_RS22260	COG1584	GPR1 FUN34 yaaH family protein
I5Q76_RS22265	COG0477	Major facilitator Superfamily
I5Q76_RS22270	COG0521	Mo-molybdopterin cofactor biosynthetic process
I5Q76_RS22275	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
I5Q76_RS22280	COG1115	amino acid carrier protein
I5Q76_RS22295	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
I5Q76_RS22305	COG0527	aspartate kinase activity
I5Q76_RS22305	COG0460	homoserine dehydrogenase
I5Q76_RS22315	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
I5Q76_RS22325	COG0745	RESPONSE REGULATOR receiver
I5Q76_RS22330	COG4452	Inner membrane protein CreD
I5Q76_RS22335	COG2205	protein histidine kinase activity
I5Q76_RS22340	COG0745	RESPONSE REGULATOR receiver
I5Q76_RS22345	COG3045	CreA protein
I5Q76_RS22350	COG3708	Transcriptional regulator
I5Q76_RS22350	COG2207	Transcriptional regulator
I5Q76_RS22370	COG0741	lytic transglycosylase activity
I5Q76_RS22375	COG0488	(ABC) transporter
I5Q76_RS22385	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
I5Q76_RS22390	COG0560	Phosphoserine phosphatase
I5Q76_RS22395	COG3726	membrane protein affecting hemolysin expression
I5Q76_RS22425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I5Q76_RS22430	COG0084	hydrolase, TatD family'
I5Q76_RS22435	COG4667	esterase of the alpha-beta hydrolase superfamily
I5Q76_RS22445	COG2823	Periplasmic or secreted lipoprotein
I5Q76_RS22455	COG1011	Hydrolase
I5Q76_RS22460	COG0456	acetyltransferase
I5Q76_RS22465	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
I5Q76_RS22500	COG3706	GGDEF domain
I5Q76_RS22505	COG4114	ferric iron reductase
I5Q76_RS22510	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5Q76_RS22510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5Q76_RS22515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I5Q76_RS22520	COG2197	response regulator
I5Q76_RS22525	COG2197	response regulator
I5Q76_RS22540	COG2966	Psort location CytoplasmicMembrane, score
I5Q76_RS22555	COG1484	DNA-dependent DNA replication
I5Q76_RS22570	COG5464	transposase or invertase
I5Q76_RS22580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
I5Q76_RS22585	COG3716	PTS system mannose fructose sorbose family IID component
I5Q76_RS22590	COG3715	PTS system
I5Q76_RS22605	COG3933	PFAM sigma-54 factor interaction domain-containing protein
I5Q76_RS22605	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
I5Q76_RS22610	COG0456	acetyltransferase
I5Q76_RS22610	COG1214	PFAM Peptidase M22, glycoprotease
I5Q76_RS22620	COG1737	Transcriptional regulator
I5Q76_RS22625	COG0800	Aldolase
I5Q76_RS22630	COG3734	2-keto-3-deoxy-galactonokinase
I5Q76_RS22635	COG4145	pantothenate transmembrane transporter activity
I5Q76_RS22645	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
I5Q76_RS22670	COG1846	Transcriptional regulator
I5Q76_RS22680	COG0179	Fumarylacetoacetate (FAA) hydrolase
I5Q76_RS22690	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS22695	COG3384	dioxygenase
I5Q76_RS22705	COG3971	2-oxopent-4-enoate hydratase activity
I5Q76_RS22725	COG2368	4-hydroxyphenylacetate
I5Q76_RS22730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I5Q76_RS22745	COG1966	Carbon starvation protein
I5Q76_RS22750	COG2879	small protein
I5Q76_RS22755	COG0523	cobalamin synthesis protein
I5Q76_RS22765	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS22770	COG5464	transposase or invertase
I5Q76_RS22775	COG1917	Cupin 2, conserved barrel domain protein
I5Q76_RS22775	COG2207	Transcriptional regulator
I5Q76_RS22785	COG2733	membrane
I5Q76_RS22800	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
I5Q76_RS22805	COG1924	4 iron, 4 sulfur cluster binding
I5Q76_RS22820	COG1566	PFAM secretion protein HlyD family protein
I5Q76_RS22830	COG5457	Domain of unknown function (DUF1127)
I5Q76_RS22835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5Q76_RS22845	COG0583	DNA-binding transcription factor activity
I5Q76_RS22850	COG2249	NAD(P)H dehydrogenase (quinone) activity
I5Q76_RS22885	COG1454	alcohol dehydrogenase
I5Q76_RS22885	COG1012	belongs to the aldehyde dehydrogenase family
I5Q76_RS22905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I5Q76_RS22915	COG4869	propanediol catabolic process
I5Q76_RS22940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5Q76_RS22945	COG1129	ABC transporter
I5Q76_RS22945	COG0842	Transport permease protein
I5Q76_RS22950	COG0842	Transport permease protein
I5Q76_RS22980	COG2850	peptidyl-arginine hydroxylation
I5Q76_RS22995	COG5002	protein histidine kinase activity
I5Q76_RS23000	COG0745	RESPONSE REGULATOR receiver
I5Q76_RS23005	COG1538	Outer membrane efflux protein
I5Q76_RS23010	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5Q76_RS23015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5Q76_RS23020	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5Q76_RS23030	COG3040	lipid binding
I5Q76_RS23035	COG0789	Transcriptional regulator
I5Q76_RS23045	COG0300	oxidoreductase activity
I5Q76_RS23060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
I5Q76_RS23080	COG3272	Protein of unknown function (DUF1722)
I5Q76_RS23085	COG4580	involved in the transport of maltose and maltodextrins
I5Q76_RS23090	COG2115	Belongs to the xylose isomerase family
I5Q76_RS23095	COG2211	Major facilitator Superfamily
I5Q76_RS23100	COG3507	Belongs to the glycosyl hydrolase 43 family
I5Q76_RS23195	COG1401	restriction endodeoxyribonuclease activity
I5Q76_RS23260	COG2815	serine threonine protein kinase
I5Q76_RS23260	COG0515	serine threonine protein kinase
I5Q76_RS23265	COG0582	viral genome integration into host DNA
I5Q76_RS23275	COG0288	reversible hydration of carbon dioxide
I5Q76_RS23280	COG0659	secondary active sulfate transmembrane transporter activity
I5Q76_RS23285	COG1064	alcohol dehydrogenase
I5Q76_RS23290	COG1175	transmembrane transport
I5Q76_RS23295	COG0395	ABC-type sugar transport system, permease component
I5Q76_RS23300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
I5Q76_RS23305	COG3842	ATPase activity
I5Q76_RS23320	COG1082	Xylose isomerase domain protein TIM barrel
I5Q76_RS23330	COG3962	Belongs to the TPP enzyme family
I5Q76_RS23335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5Q76_RS23340	COG0837	glucose binding
I5Q76_RS23340	COG1737	Transcriptional regulator
I5Q76_RS23345	COG3718	enzyme involved in inositol metabolism
I5Q76_RS23360	COG0433	COG0433 Predicted ATPase
I5Q76_RS23365	COG0795	lipopolysaccharide-transporting ATPase activity
I5Q76_RS23370	COG0795	lipopolysaccharide-transporting ATPase activity
I5Q76_RS23380	COG2927	DNA polymerase III (CHI subunit)
I5Q76_RS23385	COG0525	valine-tRNA ligase activity
I5Q76_RS23410	COG2188	Transcriptional regulator
I5Q76_RS23415	COG1288	antiporter activity
I5Q76_RS23420	COG1228	amidohydrolase
I5Q76_RS23425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5Q76_RS23430	COG2222	sugar isomerase
I5Q76_RS23435	COG2731	YhcH YjgK YiaL family protein
I5Q76_RS23470	COG1263	PTS System
I5Q76_RS23470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I5Q76_RS23475	COG0366	Alpha amylase catalytic
I5Q76_RS23480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I5Q76_RS23485	COG1486	melibiose metabolic process
I5Q76_RS23510	COG0602	queuosine metabolic process
I5Q76_RS23515	COG2026	Addiction module toxin, RelE StbE family
I5Q76_RS23520	COG3077	Addiction module antitoxin, RelB DinJ family
I5Q76_RS23525	COG3711	transcriptional antiterminator
I5Q76_RS23525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5Q76_RS23530	COG2706	6-phosphogluconolactonase activity
I5Q76_RS23545	COG3964	amidohydrolase
I5Q76_RS23585	COG0312	modulator of DNA gyrase
I5Q76_RS23610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
I5Q76_RS23620	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS23625	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS23630	COG1129	ABC transporter
I5Q76_RS23635	COG1879	ABC-type sugar transport system periplasmic component
I5Q76_RS23655	COG2105	PFAM AIG2 family protein
I5Q76_RS23660	COG2911	Protein conserved in bacteria
I5Q76_RS23665	COG0729	surface antigen
I5Q76_RS23675	COG1253	flavin adenine dinucleotide binding
I5Q76_RS23690	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
I5Q76_RS23705	COG1733	regulation of RNA biosynthetic process
I5Q76_RS23710	COG0702	epimerase
I5Q76_RS23720	COG0697	spore germination
I5Q76_RS23730	COG1113	amino acid transport
I5Q76_RS23735	COG0545	Peptidyl-prolyl cis-trans isomerase
I5Q76_RS23740	COG3061	Opacity-associated protein A
I5Q76_RS23750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
I5Q76_RS23755	COG2965	DNA replication, synthesis of RNA primer
I5Q76_RS23815	COG1073	alpha beta
I5Q76_RS23820	COG3650	response to hydrogen peroxide
I5Q76_RS23830	COG1960	acyl-CoA dehydrogenase activity
I5Q76_RS23835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I5Q76_RS23840	COG0557	exoribonuclease II activity
I5Q76_RS23855	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
I5Q76_RS23865	COG0330	HflC and HflK could
I5Q76_RS23870	COG0330	HflC and HflK could
I5Q76_RS23875	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I5Q76_RS23895	COG0860	N-Acetylmuramoyl-L-alanine amidase
I5Q76_RS23900	COG0802	atpase or kinase
I5Q76_RS23905	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
I5Q76_RS23905	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
I5Q76_RS23910	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
I5Q76_RS23930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5Q76_RS23950	COG1511	domain protein
I5Q76_RS23950	COG3264	Mechanosensitive ion channel
I5Q76_RS23965	COG1053	succinate dehydrogenase
I5Q76_RS23970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
I5Q76_RS23990	COG2076	Multidrug Resistance protein
I5Q76_RS23995	COG5510	response to toxic substance
I5Q76_RS24010	COG1509	lysine 2,3-aminomutase activity
I5Q76_RS24015	COG3039	Transposase
I5Q76_RS24080	COG0531	amino acid
I5Q76_RS24085	COG3030	protein affecting phage T7 exclusion by the F plasmid
I5Q76_RS24090	COG1027	Aspartate ammonia-lyase
I5Q76_RS24095	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
I5Q76_RS24110	COG1309	transcriptional regulator
I5Q76_RS24155	COG0457	Tetratricopeptide repeat
I5Q76_RS24160	COG1649	PFAM Uncharacterised BCR, COG1649
I5Q76_RS24160	COG0726	polysaccharide deacetylase
I5Q76_RS24165	COG1215	transferase activity, transferring glycosyl groups
I5Q76_RS24180	COG0861	Integral membrane protein TerC family
I5Q76_RS24220	COG1486	melibiose metabolic process
I5Q76_RS24225	COG2169	Transcriptional regulator
I5Q76_RS24235	COG2824	Alkylphosphonate utilization operon protein PhnA
I5Q76_RS24240	COG2764	glyoxalase bleomycin resistance protein dioxygenase
I5Q76_RS24245	COG2188	Transcriptional regulator
I5Q76_RS24250	COG3624	Phosphonate C-P lyase system protein PhnG
I5Q76_RS24255	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
I5Q76_RS24260	COG3626	phosphonate metabolism
I5Q76_RS24265	COG3627	carbon phosphorus lyase activity
I5Q76_RS24270	COG4107	phosphonate C-P lyase system protein PhnK
I5Q76_RS24275	COG4778	phosphonate C-P lyase system protein PhnL
I5Q76_RS24280	COG3454	Phosphonate metabolism
I5Q76_RS24290	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
I5Q76_RS24300	COG4191	Histidine kinase
I5Q76_RS24300	COG0784	Response regulator, receiver
I5Q76_RS24305	COG1129	ABC transporter
I5Q76_RS24310	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS24345	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
I5Q76_RS24350	COG1301	dicarboxylic acid transport
I5Q76_RS24360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
I5Q76_RS24365	COG3162	membrane
I5Q76_RS24395	COG3539	Fimbrial protein
I5Q76_RS24400	COG1346	cytolysis
I5Q76_RS24405	COG1380	Effector of murein hydrolase LrgA
I5Q76_RS24410	COG0583	DNA-binding transcription factor activity
I5Q76_RS24415	COG0025	NhaP-type Na H and K H
I5Q76_RS24420	COG2252	PERMEase
I5Q76_RS24425	COG0625	glutathione transferase activity
I5Q76_RS24430	COG0789	Transcriptional regulator
I5Q76_RS24440	COG4943	cyclic-guanylate-specific phosphodiesterase activity
I5Q76_RS24470	COG1234	tRNA 3'-trailer cleavage
I5Q76_RS24475	COG1609	Transcriptional regulator
I5Q76_RS24480	COG0483	inositol monophosphate 1-phosphatase activity
I5Q76_RS24490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I5Q76_RS24510	COG4771	TonB-dependent receptor
I5Q76_RS24515	COG0741	lytic transglycosylase activity
I5Q76_RS24530	COG2315	Protein conserved in bacteria
I5Q76_RS24535	COG0432	Pfam Uncharacterised protein family UPF0047
I5Q76_RS24550	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
I5Q76_RS24555	COG0305	Participates in initiation and elongation during chromosome replication
I5Q76_RS24570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I5Q76_RS24580	COG0735	belongs to the Fur family
I5Q76_RS24585	COG3237	CsbD-like
I5Q76_RS24595	COG0534	Mate efflux family protein
I5Q76_RS24605	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
I5Q76_RS24675	COG0251	oxidation-reduction process
I5Q76_RS24685	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
I5Q76_RS24695	COG0527	aspartate kinase activity
I5Q76_RS24745	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
I5Q76_RS24755	COG0456	acetyltransferase
I5Q76_RS24785	COG0151	Belongs to the GarS family
I5Q76_RS24795	COG4191	Histidine kinase
I5Q76_RS24800	COG3678	ATP-independent chaperone mediated protein folding
I5Q76_RS24835	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
I5Q76_RS24850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I5Q76_RS24855	COG2104	thiamine diphosphate biosynthetic process
I5Q76_RS24870	COG3706	GGDEF domain
I5Q76_RS24880	COG1447	Phosphotransferase system cellobiose-specific component IIA
I5Q76_RS24885	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
I5Q76_RS24920	COG0250	Participates in transcription elongation, termination and antitermination
I5Q76_RS24995	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
I5Q76_RS25005	COG1739	Uncharacterized protein family UPF0029
I5Q76_RS25045	COG0805	protein transport
I5Q76_RS25065	COG3165	ubiquinone biosynthetic process from chorismate
I5Q76_RS25095	COG0583	DNA-binding transcription factor activity
I5Q76_RS25100	COG0697	spore germination
I5Q76_RS25105	COG0561	phosphatase activity
I5Q76_RS25110	COG2267	carboxylic ester hydrolase activity
I5Q76_RS25115	COG1280	lysine exporter protein (LysE YggA)
I5Q76_RS25125	COG1280	lysine exporter protein (LysE YggA)
I5Q76_RS25155	COG0210	DNA helicase
I5Q76_RS25160	COG1011	Hydrolase
I5Q76_RS25190	COG3072	Adenylate cyclase
I5Q76_RS25205	COG2959	enzyme of heme biosynthesis
I5Q76_RS25210	COG3071	HemY protein
I5Q76_RS25255	COG2244	polysaccharide biosynthetic process
I5Q76_RS25260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I5Q76_RS25265	COG0456	acetyltransferase
I5Q76_RS25270	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
I5Q76_RS25275	COG1088	dTDP-glucose 4,6-dehydratase activity
I5Q76_RS25280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
I5Q76_RS25285	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
I5Q76_RS25295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
I5Q76_RS25300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
I5Q76_RS25305	COG3118	belongs to the thioredoxin family
I5Q76_RS25330	COG1811	Na channel or pump
I5Q76_RS25340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I5Q76_RS25345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I5Q76_RS25355	COG0583	DNA-binding transcription factor activity
I5Q76_RS25360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
I5Q76_RS25375	COG3978	acetolactate synthase activity
I5Q76_RS25395	COG3085	chromosome segregation
I5Q76_RS25470	COG0583	DNA-binding transcription factor activity
I5Q76_RS25485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
I5Q76_RS25500	COG3443	Belongs to the bacterial solute-binding protein 9 family
I5Q76_RS25505	COG2207	Transcriptional regulator
I5Q76_RS25515	COG0371	Dehydrogenase
I5Q76_RS25520	COG0697	spore germination
I5Q76_RS25530	COG0583	DNA-binding transcription factor activity
I5Q76_RS25540	COG0737	Belongs to the 5'-nucleotidase family
I5Q76_RS25550	COG0460	homoserine dehydrogenase
I5Q76_RS25550	COG0527	aspartate kinase activity
I5Q76_RS25555	COG0626	cystathionine gamma-synthase activity
I5Q76_RS25570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
I5Q76_RS25575	COG1609	Transcriptional regulator
I5Q76_RS25580	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
I5Q76_RS25595	COG1575	Belongs to the MenA family. Type 1 subfamily
I5Q76_RS25615	COG3678	ATP-independent chaperone mediated protein folding
I5Q76_RS25620	COG0745	RESPONSE REGULATOR receiver
I5Q76_RS25625	COG2205	protein histidine kinase activity
I5Q76_RS25630	COG2258	MOSC domain
I5Q76_RS25635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
I5Q76_RS25675	COG1129	ABC transporter
I5Q76_RS25680	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS25685	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS25690	COG1454	alcohol dehydrogenase
I5Q76_RS25700	COG2211	Major facilitator Superfamily
I5Q76_RS25760	COG0205	6-phosphofructokinase activity
I5Q76_RS25780	COG0437	4 iron, 4 sulfur cluster binding
I5Q76_RS25785	COG2864	formate dehydrogenase
I5Q76_RS25800	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
I5Q76_RS25810	COG0456	acetyltransferase
I5Q76_RS25825	COG1011	Hydrolase
I5Q76_RS25840	COG3852	Histidine kinase
I5Q76_RS25855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I5Q76_RS25875	COG0204	Acyl-transferase
I5Q76_RS25885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I5Q76_RS25890	COG3084	Protein conserved in bacteria
I5Q76_RS25900	COG1763	Mo-molybdopterin cofactor biosynthetic process
I5Q76_RS25925	COG2186	Transcriptional regulator
I5Q76_RS25930	COG0477	Major facilitator Superfamily
I5Q76_RS25935	COG1609	Transcriptional regulator
I5Q76_RS25940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5Q76_RS25950	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5Q76_RS25955	COG1129	ABC transporter
I5Q76_RS25985	COG1522	sequence-specific DNA binding
I5Q76_RS25990	COG0716	FMN binding
I5Q76_RS26005	COG3312	ion transport
I5Q76_RS26060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
I5Q76_RS26065	COG0573	inorganic phosphate transmembrane transporter activity
I5Q76_RS26070	COG0581	inorganic phosphate transmembrane transporter activity
I5Q76_RS26075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I5Q76_RS26080	COG0704	Plays a role in the regulation of phosphate uptake
I5Q76_RS26090	COG2382	esterase
I5Q76_RS26095	COG0363	glucosamine-6-phosphate deaminase activity
I5Q76_RS26100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I5Q76_RS26105	COG2252	PERMEase
I5Q76_RS26110	COG0431	NADPH-dependent FMN reductase
I5Q76_RS26115	COG2091	lysine biosynthetic process via aminoadipic acid
I5Q76_RS26145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
I5Q76_RS26185	COG2610	gluconate transmembrane transporter activity
I5Q76_RS26215	COG5001	Diguanylate cyclase
I5Q76_RS26300	COG2135	peptidase activity
I5Q76_RS26570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I5Q76_RS26570	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
I5Q76_RS26635	COG3039	Transposase
I5Q76_RS26675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
I5Q76_RS26715	COG0673	inositol 2-dehydrogenase activity
I5Q76_RS26720	COG1324	tolerance protein