locus-tag	class	description
HB789_RS00020	COG0187	DNA topoisomerase II activity
HB789_RS00025	COG0561	phosphatase activity
HB789_RS00040	COG2186	Transcriptional regulator
HB789_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
HB789_RS00050	COG0800	Aldolase
HB789_RS00070	COG2271	Major facilitator Superfamily
HB789_RS00075	COG0823	Involved in the tonB-independent uptake of proteins
HB789_RS00080	COG5645	(Lipo)protein
HB789_RS00095	COG3645	SOS response
HB789_RS00105	COG2188	Transcriptional regulator
HB789_RS00120	COG2149	membrane
HB789_RS00140	COG2610	gluconate transmembrane transporter activity
HB789_RS00150	COG0583	DNA-binding transcription factor activity
HB789_RS00155	COG2814	Major facilitator Superfamily
HB789_RS00185	COG0028	Belongs to the TPP enzyme family
HB789_RS00190	COG0440	acetolactate synthase activity
HB789_RS00195	COG2197	response regulator
HB789_RS00205	COG2271	Major facilitator Superfamily
HB789_RS00245	COG2188	Transcriptional regulator
HB789_RS00270	COG4580	involved in the transport of maltose and maltodextrins
HB789_RS00275	COG1447	Phosphotransferase system cellobiose-specific component IIA
HB789_RS00280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS00280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS00290	COG1609	Transcriptional regulator
HB789_RS00300	COG3384	dioxygenase
HB789_RS00305	COG0583	DNA-binding transcription factor activity
HB789_RS00310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HB789_RS00315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB789_RS00320	COG2828	Protein conserved in bacteria
HB789_RS00335	COG0697	spore germination
HB789_RS00340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB789_RS00340	COG1263	PTS System
HB789_RS00350	COG2814	Major facilitator Superfamily
HB789_RS00360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB789_RS00395	COG0583	DNA-binding transcription factor activity
HB789_RS00420	COG1464	Belongs to the NlpA lipoprotein family
HB789_RS00435	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HB789_RS00445	COG1064	alcohol dehydrogenase
HB789_RS00475	COG2211	Major facilitator Superfamily
HB789_RS00480	COG1501	Belongs to the glycosyl hydrolase 31 family
HB789_RS00490	COG1486	melibiose metabolic process
HB789_RS00495	COG1263	PTS System
HB789_RS00495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB789_RS00500	COG2982	Protein involved in outer membrane biogenesis
HB789_RS00505	COG2233	PERMEase
HB789_RS00510	COG0786	glutamate:sodium symporter activity
HB789_RS00530	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HB789_RS00555	COG3152	Membrane
HB789_RS00565	COG1494	fructose-1,6-bisphosphatase
HB789_RS00570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HB789_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB789_RS00580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB789_RS00600	COG2860	membrane
HB789_RS00610	COG2169	Transcriptional regulator
HB789_RS00610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HB789_RS00615	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HB789_RS00620	COG1561	YicC-like family, N-terminal region
HB789_RS00625	COG3039	Transposase
HB789_RS00660	COG0842	Transport permease protein
HB789_RS00685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HB789_RS00720	COG1519	Transferase
HB789_RS00725	COG1216	Glycosyl transferase, family 2
HB789_RS00730	COG0438	transferase activity, transferring glycosyl groups
HB789_RS00740	COG0859	PFAM glycosyl transferase family 9
HB789_RS00765	COG0859	PFAM glycosyl transferase family 9
HB789_RS00780	COG0156	8-amino-7-oxononanoate synthase activity
HB789_RS00790	COG0463	Glycosyl transferase, family 2
HB789_RS00795	COG2861	carbohydrate metabolic process
HB789_RS00800	COG4942	peptidase
HB789_RS00810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HB789_RS00815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB789_RS00835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HB789_RS00845	COG2186	Transcriptional regulator
HB789_RS00865	COG3722	fumarate hydratase activity
HB789_RS00885	COG1566	PFAM secretion protein HlyD family protein
HB789_RS00890	COG0625	glutathione transferase activity
HB789_RS00900	COG3276	selenocysteine insertion sequence binding
HB789_RS00905	COG1414	Transcriptional regulator
HB789_RS00910	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB789_RS00915	COG3977	Valine--pyruvate aminotransferase
HB789_RS00920	COG0366	Alpha amylase catalytic
HB789_RS00925	COG2992	FlgJ-related protein
HB789_RS00930	COG2207	Transcriptional regulator
HB789_RS00930	COG1609	Transcriptional regulator
HB789_RS00935	COG4214	carbohydrate transport
HB789_RS00945	COG4213	ABC transporter substrate-binding protein
HB789_RS00960	COG4682	membrane
HB789_RS00965	COG4682	membrane
HB789_RS00970	COG3274	enterobacterial common antigen metabolic process
HB789_RS01005	COG1278	Cold shock
HB789_RS01010	COG2944	sequence-specific DNA binding
HB789_RS01015	COG2814	Major facilitator Superfamily
HB789_RS01035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB789_RS01045	COG1609	Transcriptional regulator
HB789_RS01050	COG2885	chlorophyll binding
HB789_RS01055	COG0243	molybdopterin cofactor binding
HB789_RS01060	COG0456	acetyltransferase
HB789_RS01065	COG2818	Glycosylase
HB789_RS01070	COG5571	outer membrane autotransporter
HB789_RS01075	COG2223	nitrite transmembrane transporter activity
HB789_RS01105	COG0747	negative chemotaxis
HB789_RS01110	COG0601	transmembrane transport
HB789_RS01115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB789_RS01120	COG0444	Belongs to the ABC transporter superfamily
HB789_RS01125	COG4608	Belongs to the ABC transporter superfamily
HB789_RS01150	COG1215	transferase activity, transferring glycosyl groups
HB789_RS01155	COG0457	Tetratricopeptide repeat
HB789_RS01170	COG2194	sulfuric ester hydrolase activity
HB789_RS01200	COG1215	transferase activity, transferring glycosyl groups
HB789_RS01205	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HB789_RS01210	COG0457	Tetratricopeptide repeat
HB789_RS01210	COG3118	belongs to the thioredoxin family
HB789_RS01215	COG2199	diguanylate cyclase activity
HB789_RS01215	COG2200	EAL domain
HB789_RS01225	COG0612	Peptidase, M16
HB789_RS01235	COG2982	Protein involved in outer membrane biogenesis
HB789_RS01240	COG0477	Major facilitator Superfamily
HB789_RS01245	COG1295	ribonuclease BN
HB789_RS01250	COG0583	DNA-binding transcription factor activity
HB789_RS01255	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS01260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB789_RS01270	COG1454	alcohol dehydrogenase
HB789_RS01280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB789_RS01285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HB789_RS01290	COG0671	phosphoesterase, PA-phosphatase related
HB789_RS01310	COG0589	response to stress
HB789_RS01320	COG0306	phosphate transporter
HB789_RS01325	COG2081	HI0933 family
HB789_RS01330	COG2239	Acts as a magnesium transporter
HB789_RS01340	COG1124	(ABC) transporter
HB789_RS01350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB789_RS01355	COG0601	transmembrane transport
HB789_RS01360	COG0747	negative chemotaxis
HB789_RS01370	COG3479	Phenolic acid decarboxylase
HB789_RS01410	COG0628	permease
HB789_RS01415	COG0477	Major facilitator Superfamily
HB789_RS01425	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HB789_RS01440	COG3714	YhhN family
HB789_RS01450	COG3776	membrane
HB789_RS01455	COG0742	ribosomal rna small subunit methyltransferase
HB789_RS01460	COG0552	protein localization to endoplasmic reticulum
HB789_RS01465	COG2884	Cell division ATP-binding protein ftsE
HB789_RS01470	COG2177	Part of the ABC transporter FtsEX involved in
HB789_RS01485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HB789_RS01495	COG0683	leucine binding
HB789_RS01505	COG0683	leucine binding
HB789_RS01510	COG0559	Belongs to the binding-protein-dependent transport system permease family
HB789_RS01560	COG0584	glycerophosphoryl diester phosphodiesterase
HB789_RS01570	COG0405	Gamma-glutamyltransferase
HB789_RS01575	COG1247	-acetyltransferase
HB789_RS01585	COG0673	inositol 2-dehydrogenase activity
HB789_RS01590	COG1741	Belongs to the pirin family
HB789_RS01595	COG1609	Transcriptional regulator
HB789_RS01600	COG3265	gluconokinase activity
HB789_RS01605	COG2610	gluconate transmembrane transporter activity
HB789_RS01615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HB789_RS01640	COG0058	SHG alpha-glucan phosphorylase activity
HB789_RS01655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HB789_RS01670	COG1349	DNA-binding transcription factor activity
HB789_RS01680	COG0058	SHG alpha-glucan phosphorylase activity
HB789_RS01685	COG1640	4-alpha-glucanotransferase
HB789_RS01690	COG2610	gluconate transmembrane transporter activity
HB789_RS01700	COG1040	competence protein
HB789_RS01725	COG1918	ferrous iron import across plasma membrane
HB789_RS01730	COG2183	response to ionizing radiation
HB789_RS01735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB789_RS01760	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HB789_RS01765	COG1011	Hydrolase
HB789_RS01775	COG0494	nUDIX hydrolase
HB789_RS01780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HB789_RS01805	COG4796	Type ii and iii secretion system protein
HB789_RS01820	COG3266	domain, Protein
HB789_RS01825	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HB789_RS01830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HB789_RS01855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HB789_RS01860	COG0402	S-adenosylhomocysteine deaminase activity
HB789_RS01865	COG0738	Major facilitator superfamily
HB789_RS01890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HB789_RS01895	COG1289	transmembrane transporter activity
HB789_RS01905	COG1765	OsmC-like protein
HB789_RS01910	COG3954	Phosphoribulokinase
HB789_RS01920	COG0429	hydrolase of the alpha beta-hydrolase fold
HB789_RS01925	COG0488	(ABC) transporter
HB789_RS01940	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HB789_RS01945	COG1047	Peptidyl-prolyl cis-trans
HB789_RS01955	COG0545	Peptidyl-prolyl cis-trans isomerase
HB789_RS01960	COG2964	Protein conserved in bacteria
HB789_RS02015	COG0051	transcription antitermination factor activity, RNA binding
HB789_RS02040	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HB789_RS02055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HB789_RS02120	COG0201	protein transport
HB789_RS02145	COG0202	RNA polymerase activity
HB789_RS02160	COG0789	Transcriptional regulator
HB789_RS02165	COG3036	rescue of stalled ribosome
HB789_RS02195	COG0758	DNA mediated transformation
HB789_RS02205	COG0551	DNA topoisomerase type I activity
HB789_RS02225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HB789_RS02260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB789_RS02265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB789_RS02270	COG1309	transcriptional regulator
HB789_RS02275	COG0582	viral genome integration into host DNA
HB789_RS02290	COG3561	AntA/AntB antirepressor
HB789_RS02375	COG1802	Transcriptional regulator
HB789_RS02375	COG4626	Terminase
HB789_RS02400	COG4145	pantothenate transmembrane transporter activity
HB789_RS02405	COG3924	membrane
HB789_RS02410	COG0439	Biotin carboxylase
HB789_RS02415	COG0511	ligase activity, forming carbon-carbon bonds
HB789_RS02440	COG2199	diguanylate cyclase activity
HB789_RS02440	COG2200	EAL domain
HB789_RS02445	COG1077	Cell shape determining protein MreB Mrl
HB789_RS02450	COG1792	Involved in formation and maintenance of cell shape
HB789_RS02455	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HB789_RS02465	COG1530	ribonuclease E activity
HB789_RS02470	COG3164	Protein of unknown function
HB789_RS02475	COG0312	modulator of DNA gyrase
HB789_RS02480	COG0583	DNA-binding transcription factor activity
HB789_RS02495	COG1289	transmembrane transporter activity
HB789_RS02500	COG2732	(Barnase) inhibitor
HB789_RS02525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB789_RS02530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB789_RS02535	COG3105	Protein conserved in bacteria
HB789_RS02540	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HB789_RS02560	COG0625	glutathione transferase activity
HB789_RS02565	COG2969	positive regulation of protein catabolic process
HB789_RS02575	COG0493	'glutamate synthase
HB789_RS02580	COG0067	glutamate synthase
HB789_RS02580	COG0069	glutamate synthase activity
HB789_RS02580	COG0070	glutamate synthase
HB789_RS02585	COG1242	4 iron, 4 sulfur cluster binding
HB789_RS02590	COG2271	Major facilitator Superfamily
HB789_RS02595	COG1063	alcohol dehydrogenase
HB789_RS02600	COG1312	Catalyzes the dehydration of D-mannonate
HB789_RS02605	COG0784	Response regulator, receiver
HB789_RS02605	COG2198	Histidine kinase
HB789_RS02605	COG5002	protein histidine kinase activity
HB789_RS02610	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HB789_RS02615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB789_RS02620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS02630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS02635	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HB789_RS02640	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HB789_RS02645	COG1137	ATPase activity
HB789_RS02650	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HB789_RS02655	COG3117	lipopolysaccharide transmembrane transporter activity
HB789_RS02660	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HB789_RS02670	COG0530	calcium, potassium:sodium antiporter activity
HB789_RS02675	COG1127	ABC transporter
HB789_RS02680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HB789_RS02685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB789_RS02690	COG2854	intermembrane phospholipid transfer
HB789_RS02695	COG3113	response to antibiotic
HB789_RS02700	COG5007	Belongs to the BolA IbaG family
HB789_RS02710	COG3423	Transcriptional regulator
HB789_RS02715	COG0142	geranyltranstransferase activity
HB789_RS02730	COG0697	spore germination
HB789_RS02740	COG2027	D-alanyl-D-alanine carboxypeptidase
HB789_RS02750	COG1534	Rna-binding protein
HB789_RS02760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HB789_RS02765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HB789_RS02775	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HB789_RS02815	COG0195	Participates in both transcription termination and antitermination
HB789_RS02860	COG0814	amino acid
HB789_RS02865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HB789_RS02870	COG0826	peptidase U32
HB789_RS02875	COG0826	peptidase U32
HB789_RS02880	COG3154	lipid carrier protein
HB789_RS02885	COG3153	acetyltransferase
HB789_RS02900	COG0693	protein deglycase activity
HB789_RS02905	COG0702	epimerase
HB789_RS02910	COG0701	Predicted permease
HB789_RS02915	COG2823	Periplasmic or secreted lipoprotein
HB789_RS02935	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HB789_RS02950	COG1063	alcohol dehydrogenase
HB789_RS02955	COG3775	system Galactitol-specific IIC component
HB789_RS02960	COG3414	Phosphotransferase system galactitol-specific IIB component
HB789_RS02965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS02975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS02975	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS02980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB789_RS02980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB789_RS02980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS02985	COG1105	Belongs to the carbohydrate kinase PfkB family
HB789_RS02995	COG1349	DNA-binding transcription factor activity
HB789_RS03000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB789_RS03005	COG2721	sulfolactate sulfo-lyase activity
HB789_RS03010	COG2271	Major facilitator Superfamily
HB789_RS03020	COG2084	Dehydrogenase
HB789_RS03025	COG1929	Belongs to the glycerate kinase type-1 family
HB789_RS03050	COG1741	Belongs to the pirin family
HB789_RS03055	COG0583	DNA-binding transcription factor activity
HB789_RS03060	COG3152	Membrane
HB789_RS03065	COG0435	Glutathione S-transferase
HB789_RS03070	COG2259	Doxx family
HB789_RS03080	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HB789_RS03085	COG4575	ribosome binding
HB789_RS03090	COG1422	Protein of unknown function (DUF1090)
HB789_RS03100	COG0586	Pfam SNARE associated Golgi protein
HB789_RS03105	COG2186	Transcriptional regulator
HB789_RS03110	COG2271	Major facilitator Superfamily
HB789_RS03120	COG2721	sulfolactate sulfo-lyase activity
HB789_RS03135	COG0861	Integral membrane protein TerC family
HB789_RS03140	COG0673	inositol 2-dehydrogenase activity
HB789_RS03145	COG1451	nucleotide metabolic process
HB789_RS03165	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB789_RS03165	COG1902	pentaerythritol trinitrate reductase activity
HB789_RS03215	COG1695	Transcriptional regulator
HB789_RS03220	COG2375	cellular response to nickel ion
HB789_RS03235	COG1461	Dihydroxyacetone kinase
HB789_RS03240	COG2376	Dihydroxyacetone kinase
HB789_RS03310	COG3247	response to pH
HB789_RS03335	COG2197	response regulator
HB789_RS03360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HB789_RS03365	COG0358	DNA primase activity
HB789_RS03370	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HB789_RS03440	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HB789_RS03455	COG4991	sh3 domain protein
HB789_RS03460	COG3025	triphosphatase activity
HB789_RS03485	COG2960	long-chain fatty acid transporting porin activity
HB789_RS03500	COG3384	dioxygenase
HB789_RS03505	COG0754	glutathionylspermidine amidase activity
HB789_RS03520	COG0494	nUDIX hydrolase
HB789_RS03525	COG3151	Protein conserved in bacteria
HB789_RS03530	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HB789_RS03535	COG3150	esterase
HB789_RS03545	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HB789_RS03550	COG2249	NAD(P)H dehydrogenase (quinone) activity
HB789_RS03555	COG0642	Histidine kinase
HB789_RS03565	COG3111	PFAM Bacterial OB fold (BOF) protein
HB789_RS03570	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HB789_RS03575	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HB789_RS03580	COG0204	Acyl-transferase
HB789_RS03585	COG2132	Multicopper oxidase
HB789_RS03590	COG1032	radical SAM domain protein
HB789_RS03600	COG0656	L-ascorbic acid biosynthetic process
HB789_RS03605	COG1979	alcohol dehydrogenase
HB789_RS03610	COG2207	Transcriptional regulator
HB789_RS03615	COG0586	Pfam SNARE associated Golgi protein
HB789_RS03620	COG0626	cystathionine gamma-synthase activity
HB789_RS03630	COG0848	biopolymer transport protein
HB789_RS03635	COG2211	Major facilitator Superfamily
HB789_RS03660	COG0625	glutathione transferase activity
HB789_RS03675	COG0754	glutathionylspermidine amidase activity
HB789_RS03680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB789_RS03700	COG0583	DNA-binding transcription factor activity
HB789_RS03705	COG0626	cystathionine gamma-synthase activity
HB789_RS03970	COG3423	Transcriptional regulator
HB789_RS03980	COG1278	Cold shock
HB789_RS03985	COG3423	Transcriptional regulator
HB789_RS04055	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HB789_RS04065	COG1811	Na channel or pump
HB789_RS04070	COG1982	Orn Lys Arg decarboxylase major
HB789_RS04075	COG2211	Major facilitator Superfamily
HB789_RS04090	COG1194	a g-specific adenine glycosylase
HB789_RS04100	COG3171	Protein conserved in bacteria
HB789_RS04110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HB789_RS04125	COG0762	integral membrane protein
HB789_RS04130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HB789_RS04135	COG2805	Type II/IV secretion system protein
HB789_RS04155	COG0189	ligase activity
HB789_RS04160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HB789_RS04165	COG2356	endonuclease I
HB789_RS04175	COG2814	Major facilitator Superfamily
HB789_RS04210	COG2146	nitrite reductase [NAD(P)H] activity
HB789_RS04225	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS04230	COG1414	Transcriptional regulator
HB789_RS04260	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS04265	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HB789_RS04290	COG0501	Belongs to the peptidase M48B family
HB789_RS04295	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB789_RS04310	COG0191	fructose-bisphosphate aldolase activity
HB789_RS04315	COG0668	transmembrane transport
HB789_RS04325	COG2968	Membrane
HB789_RS04340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB789_RS04345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HB789_RS04365	COG0006	proline dipeptidase activity
HB789_RS04370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB789_RS04375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB789_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS04400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HB789_RS04420	COG2723	6-phospho-beta-galactosidase activity
HB789_RS04425	COG1737	Transcriptional regulator
HB789_RS04435	COG1272	protein, Hemolysin III
HB789_RS04445	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HB789_RS04455	COG0716	FMN binding
HB789_RS04460	COG4974	Belongs to the 'phage' integrase family
HB789_RS04470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HB789_RS04490	COG4942	peptidase
HB789_RS04500	COG2814	Major facilitator Superfamily
HB789_RS04515	COG0667	Aldo Keto reductase
HB789_RS04550	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HB789_RS04555	COG1393	Belongs to the ArsC family
HB789_RS04570	COG1538	Outer membrane efflux protein
HB789_RS04575	COG1289	transmembrane transporter activity
HB789_RS04590	COG3592	Divergent 4Fe-4S mono-cluster
HB789_RS04595	COG2388	GCN5-related N-acetyl-transferase
HB789_RS04605	COG3539	Fimbrial protein
HB789_RS04610	COG3539	Fimbrial protein
HB789_RS04615	COG3539	Fimbrial protein
HB789_RS04620	COG3188	usher protein
HB789_RS04625	COG3121	Chaperone
HB789_RS04630	COG3539	Fimbrial protein
HB789_RS04640	COG4974	Belongs to the 'phage' integrase family
HB789_RS04645	COG0582	viral genome integration into host DNA
HB789_RS04650	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HB789_RS04655	COG1846	Transcriptional regulator
HB789_RS04660	COG0697	spore germination
HB789_RS04710	COG0667	Aldo Keto reductase
HB789_RS04715	COG0814	amino acid
HB789_RS04730	COG0183	Belongs to the thiolase family
HB789_RS04740	COG0823	Involved in the tonB-independent uptake of proteins
HB789_RS04745	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS04750	COG2814	Major facilitator Superfamily
HB789_RS04785	COG3842	ATPase activity
HB789_RS04790	COG0395	ABC-type sugar transport system, permease component
HB789_RS04795	COG1175	transmembrane transport
HB789_RS04800	COG1917	Cupin 2, conserved barrel domain protein
HB789_RS04805	COG1794	racemase activity, acting on amino acids and derivatives
HB789_RS04810	COG0583	DNA-binding transcription factor activity
HB789_RS04820	COG1609	Transcriptional regulator
HB789_RS04825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS04830	COG2723	6-phospho-beta-galactosidase activity
HB789_RS04835	COG2186	Transcriptional regulator
HB789_RS04845	COG1609	Transcriptional regulator
HB789_RS04865	COG0667	Aldo Keto reductase
HB789_RS04875	COG0861	Integral membrane protein TerC family
HB789_RS04910	COG2165	general secretion pathway protein
HB789_RS04915	COG4795	General secretion pathway protein
HB789_RS04925	COG4967	type IV pilus modification protein PilV
HB789_RS04930	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HB789_RS04935	COG1025	Belongs to the peptidase M16 family
HB789_RS04940	COG1074	ATP-dependent DNA helicase activity
HB789_RS04945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HB789_RS04955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HB789_RS04955	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HB789_RS04960	COG0860	N-Acetylmuramoyl-L-alanine amidase
HB789_RS04965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HB789_RS04995	COG4656	Part of a membrane complex involved in electron transport
HB789_RS05000	COG1454	alcohol dehydrogenase
HB789_RS05000	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS05030	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HB789_RS05195	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HB789_RS05200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HB789_RS05205	COG2166	iron-sulfur cluster assembly
HB789_RS05210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB789_RS05220	COG0583	DNA-binding transcription factor activity
HB789_RS05225	COG2363	Small membrane protein
HB789_RS05235	COG1349	DNA-binding transcription factor activity
HB789_RS05255	COG0738	Major facilitator superfamily
HB789_RS05260	COG0235	Class ii aldolase
HB789_RS05265	COG1454	alcohol dehydrogenase
HB789_RS05285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HB789_RS05300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HB789_RS05305	COG2011	ABC-type metal ion transport system permease component
HB789_RS05310	COG1464	Belongs to the NlpA lipoprotein family
HB789_RS05315	COG0477	Major facilitator Superfamily
HB789_RS05325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB789_RS05330	COG1760	l-serine dehydratase
HB789_RS05335	COG0814	amino acid
HB789_RS05340	COG1611	Belongs to the LOG family
HB789_RS05355	COG3098	single-species biofilm formation
HB789_RS05360	COG0564	pseudouridine synthase activity
HB789_RS05365	COG0716	FMN binding
HB789_RS05370	COG2271	Major facilitator Superfamily
HB789_RS05375	COG4948	Mandelate Racemase Muconate Lactonizing
HB789_RS05380	COG4948	Mandelate Racemase Muconate Lactonizing
HB789_RS05385	COG1929	Belongs to the glycerate kinase type-1 family
HB789_RS05390	COG3437	response regulator, receiver
HB789_RS05390	COG4999	Histidine kinase
HB789_RS05390	COG3850	Histidine kinase
HB789_RS05390	COG2205	protein histidine kinase activity
HB789_RS05400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB789_RS05405	COG3956	TIGRFAM MazG family protein
HB789_RS05425	COG0602	queuosine metabolic process
HB789_RS05430	COG0720	synthase
HB789_RS05450	COG2234	aminopeptidase activity
HB789_RS05510	COG1388	LysM domain
HB789_RS05510	COG4942	peptidase
HB789_RS05515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HB789_RS05540	COG0163	prenyltransferase activity
HB789_RS05545	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HB789_RS05585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB789_RS05590	COG4558	Periplasmic binding protein
HB789_RS05595	COG3720	iron ion transport
HB789_RS05615	COG0679	Auxin Efflux Carrier
HB789_RS05630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB789_RS05635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB789_RS05640	COG1121	(ABC) transporter
HB789_RS05645	COG0803	Belongs to the bacterial solute-binding protein 9 family
HB789_RS05650	COG1609	Transcriptional regulator
HB789_RS05655	COG1940	carbohydrate kinase activity
HB789_RS05660	COG1447	Phosphotransferase system cellobiose-specific component IIA
HB789_RS05665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS05670	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS05675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS05680	COG4580	involved in the transport of maltose and maltodextrins
HB789_RS05690	COG2723	6-phospho-beta-galactosidase activity
HB789_RS05700	COG0309	Hydrogenase expression formation protein (HypE)
HB789_RS05705	COG0409	Hydrogenase expression formation protein
HB789_RS05710	COG0298	carbon dioxide binding
HB789_RS05715	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HB789_RS05730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB789_RS05735	COG0651	ATP synthesis coupled electron transport
HB789_RS05740	COG0650	Formate hydrogenlyase subunit 4
HB789_RS05745	COG3261	NADH dehydrogenase
HB789_RS05745	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HB789_RS05750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HB789_RS05755	COG3260	NADH ubiquinone oxidoreductase 20
HB789_RS05765	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HB789_RS05775	COG2723	6-phospho-beta-galactosidase activity
HB789_RS05780	COG1263	PTS System
HB789_RS05780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB789_RS05785	COG1609	Transcriptional regulator
HB789_RS05790	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB789_RS05795	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HB789_RS05800	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HB789_RS05825	COG1349	DNA-binding transcription factor activity
HB789_RS05830	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS05835	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS05845	COG3732	PTS system glucitol sorbitol-specific
HB789_RS05850	COG3730	PTS system glucitol sorbitol-specific
HB789_RS05855	COG2951	lytic endotransglycosylase activity
HB789_RS05860	COG1121	(ABC) transporter
HB789_RS05865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB789_RS05875	COG1546	Belongs to the CinA family
HB789_RS05895	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HB789_RS05925	COG2823	Periplasmic or secreted lipoprotein
HB789_RS05930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB789_RS05935	COG1238	metal cluster binding
HB789_RS05955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HB789_RS05960	COG2814	Major facilitator Superfamily
HB789_RS05965	COG1566	PFAM secretion protein HlyD family protein
HB789_RS05970	COG1846	Transcriptional regulator
HB789_RS05980	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HB789_RS05990	COG4176	ABC-type proline glycine betaine transport system permease component
HB789_RS06005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB789_RS06015	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB789_RS06020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HB789_RS06025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB789_RS06030	COG4575	ribosome binding
HB789_RS06045	COG2916	Histone family protein nucleoid-structuring protein H-NS
HB789_RS06060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HB789_RS06065	COG0640	Transcriptional regulator
HB789_RS06075	COG0583	DNA-binding transcription factor activity
HB789_RS06080	COG3284	Transcriptional regulator
HB789_RS06090	COG3539	Fimbrial protein
HB789_RS06095	COG3121	Chaperone
HB789_RS06115	COG3188	usher protein
HB789_RS06125	COG3539	Fimbrial protein
HB789_RS06140	COG4974	Belongs to the 'phage' integrase family
HB789_RS06175	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HB789_RS06200	COG3344	reverse transcriptase
HB789_RS06245	COG4695	Portal protein
HB789_RS06410	COG2867	negative regulation of translational initiation
HB789_RS06425	COG0497	DNA recombination
HB789_RS06440	COG4536	flavin adenine dinucleotide binding
HB789_RS06445	COG4137	Cytochrome C assembly protein
HB789_RS06450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HB789_RS06485	COG2885	chlorophyll binding
HB789_RS06490	COG2199	diguanylate cyclase activity
HB789_RS06500	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB789_RS06505	COG1605	Chorismate mutase
HB789_RS06505	COG0287	Prephenate dehydrogenase
HB789_RS06515	COG0077	Prephenate dehydratase
HB789_RS06515	COG1605	Chorismate mutase
HB789_RS06525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HB789_RS06530	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB789_RS06545	COG0542	response to heat
HB789_RS06570	COG0477	Major facilitator Superfamily
HB789_RS06575	COG5544	Lipoprotein
HB789_RS06580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HB789_RS06590	COG3148	PFAM DTW domain containing protein
HB789_RS06595	COG3118	belongs to the thioredoxin family
HB789_RS06600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB789_RS06615	COG0513	Belongs to the DEAD box helicase family
HB789_RS06625	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HB789_RS06640	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HB789_RS06645	COG3026	antisigma factor binding
HB789_RS06650	COG3086	response to oxidative stress
HB789_RS06660	COG0681	Belongs to the peptidase S26 family
HB789_RS06680	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HB789_RS06690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB789_RS06695	COG1737	Transcriptional regulator
HB789_RS06700	COG0560	Phosphoserine phosphatase
HB789_RS06715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HB789_RS06715	COG0047	phosphoribosylformylglycinamidine synthase activity
HB789_RS06720	COG2205	protein histidine kinase activity
HB789_RS06725	COG3170	Tfp pilus assembly protein FimV
HB789_RS06730	COG2204	response regulator
HB789_RS06735	COG0347	Belongs to the P(II) protein family
HB789_RS06740	COG1017	nitric oxide dioxygenase activity
HB789_RS06740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB789_RS06750	COG2259	Doxx family
HB789_RS06755	COG1940	carbohydrate kinase activity
HB789_RS06760	COG0457	Tetratricopeptide repeat
HB789_RS06765	COG0477	Major facilitator Superfamily
HB789_RS06765	COG2814	Major facilitator Superfamily
HB789_RS06770	COG2017	converts alpha-aldose to the beta-anomer
HB789_RS06775	COG2814	Major facilitator Superfamily
HB789_RS06780	COG3711	transcriptional antiterminator
HB789_RS06785	COG3683	transport system, periplasmic component
HB789_RS06790	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HB789_RS06820	COG0822	iron-sulfur transferase activity
HB789_RS06840	COG0633	Ferredoxin
HB789_RS06845	COG2975	iron-sulfur cluster assembly
HB789_RS06865	COG2897	thiosulfate sulfurtransferase activity
HB789_RS06870	COG2373	Large extracellular alpha-helical protein
HB789_RS06875	COG4953	penicillin-binding protein 1C
HB789_RS06905	COG2976	Protein conserved in bacteria
HB789_RS06925	COG1645	bacterial-type flagellum-dependent swarming motility
HB789_RS06935	COG0517	IMP dehydrogenase activity
HB789_RS06935	COG0516	GMP reductase activity
HB789_RS06985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HB789_RS07070	COG3344	reverse transcriptase
HB789_RS07080	COG5484	DNA packaging
HB789_RS07080	COG3728	DNA packaging
HB789_RS07220	COG3179	chitinase
HB789_RS07230	COG3119	arylsulfatase activity
HB789_RS07235	COG0641	radical SAM
HB789_RS07255	COG2200	EAL domain
HB789_RS07270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HB789_RS07285	COG2723	6-phospho-beta-galactosidase activity
HB789_RS07295	COG2233	PERMEase
HB789_RS07310	COG1393	Belongs to the ArsC family
HB789_RS07315	COG4783	chaperone-mediated protein folding
HB789_RS07325	COG0628	permease
HB789_RS07330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HB789_RS07335	COG2716	regulation of RNA biosynthetic process
HB789_RS07345	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HB789_RS07355	COG2321	neutral zinc metallopeptidase
HB789_RS07360	COG1444	tRNA N-acetyltransferase activity
HB789_RS07365	COG0400	carboxylic ester hydrolase activity
HB789_RS07380	COG1393	Belongs to the ArsC family
HB789_RS07390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB789_RS07395	COG0493	'glutamate synthase
HB789_RS07395	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB789_RS07405	COG5342	invasion associated locus B
HB789_RS07410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB789_RS07415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HB789_RS07425	COG4810	utilization protein
HB789_RS07515	COG0860	N-Acetylmuramoyl-L-alanine amidase
HB789_RS07535	COG2837	iron assimilation
HB789_RS07545	COG4150	thiosulfate binding
HB789_RS07550	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HB789_RS07555	COG4208	sulfate ABC transporter
HB789_RS07560	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HB789_RS07570	COG4319	ketosteroid isomerase
HB789_RS07605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HB789_RS07625	COG3530	Putative quorum-sensing-regulated virulence factor
HB789_RS07630	COG0385	Bile acid
HB789_RS07635	COG0583	DNA-binding transcription factor activity
HB789_RS07665	COG3415	Transposase
HB789_RS07670	COG3415	Transposase
HB789_RS07685	COG2199	diguanylate cyclase activity
HB789_RS07685	COG2200	EAL domain
HB789_RS07690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB789_RS07705	COG0667	Aldo Keto reductase
HB789_RS07710	COG3961	Belongs to the TPP enzyme family
HB789_RS07725	COG3279	Response regulator of the LytR AlgR family
HB789_RS07730	COG3275	phosphorelay sensor kinase activity
HB789_RS07745	COG0436	Aminotransferase
HB789_RS07755	COG2807	transmembrane transport
HB789_RS07760	COG0590	tRNA wobble adenosine to inosine editing
HB789_RS07765	COG0583	DNA-binding transcription factor activity
HB789_RS07785	COG2116	formate transmembrane transporter activity
HB789_RS07790	COG2853	Lipoprotein
HB789_RS07800	COG3691	Protein conserved in bacteria
HB789_RS07815	COG2062	phosphohistidine phosphatase, SixA
HB789_RS07840	COG0730	response to heat
HB789_RS07845	COG3101	peptidyl-lysine hydroxylation
HB789_RS07860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HB789_RS07880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HB789_RS07890	COG0586	Pfam SNARE associated Golgi protein
HB789_RS07900	COG0285	dihydrofolate synthase activity
HB789_RS07905	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HB789_RS07910	COG1286	toxin biosynthetic process
HB789_RS07915	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HB789_RS07920	COG0163	prenyltransferase activity
HB789_RS07945	COG4160	amino acid transport
HB789_RS07950	COG4598	ABC transporter
HB789_RS07965	COG1090	epimerase
HB789_RS07970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HB789_RS07975	COG0625	glutathione transferase activity
HB789_RS07980	COG0625	glutathione transferase activity
HB789_RS07985	COG0622	Phosphoesterase
HB789_RS07990	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HB789_RS07995	COG0280	phosphate acetyltransferase
HB789_RS07995	COG0857	belongs to the CobB CobQ family
HB789_RS08015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB789_RS08020	COG0471	metal ion transport
HB789_RS08020	COG0490	domain, Protein
HB789_RS08030	COG0436	Aminotransferase
HB789_RS08035	COG0583	DNA-binding transcription factor activity
HB789_RS08080	COG0839	Belongs to the complex I subunit 6 family
HB789_RS08090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HB789_RS08095	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HB789_RS08110	COG2153	protein acetylation
HB789_RS08115	COG1169	isochorismate synthase
HB789_RS08140	COG0318	PFAM AMP-dependent synthetase and ligase
HB789_RS08150	COG5464	transposase or invertase
HB789_RS08165	COG1414	Transcriptional regulator
HB789_RS08175	COG2271	Major facilitator Superfamily
HB789_RS08185	COG0247	lactate metabolic process
HB789_RS08195	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HB789_RS08200	COG2271	Major facilitator Superfamily
HB789_RS08205	COG0584	glycerophosphoryl diester phosphodiesterase
HB789_RS08210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB789_RS08235	COG2205	protein histidine kinase activity
HB789_RS08235	COG0784	Response regulator, receiver
HB789_RS08245	COG0642	Histidine kinase
HB789_RS08245	COG2198	Histidine kinase
HB789_RS08260	COG2169	Transcriptional regulator
HB789_RS08260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HB789_RS08265	COG3145	DNA-N1-methyladenine dioxygenase activity
HB789_RS08270	COG4615	Cyclic peptide transporter
HB789_RS08275	COG2239	Acts as a magnesium transporter
HB789_RS08280	COG0659	secondary active sulfate transmembrane transporter activity
HB789_RS08295	COG0628	permease
HB789_RS08320	COG1349	DNA-binding transcription factor activity
HB789_RS08325	COG0494	nUDIX hydrolase
HB789_RS08345	COG1061	Type III restriction enzyme res subunit
HB789_RS08350	COG1187	pseudouridine synthase activity
HB789_RS08355	COG2814	Major facilitator Superfamily
HB789_RS08365	COG4172	Belongs to the ABC transporter superfamily
HB789_RS08370	COG4239	(ABC) transporter, permease
HB789_RS08375	COG4174	ABC transporter (Permease)
HB789_RS08380	COG4166	transmembrane transport
HB789_RS08385	COG2200	EAL domain
HB789_RS08390	COG0791	NLP P60 protein
HB789_RS08395	COG0671	phosphoesterase, PA-phosphatase related
HB789_RS08400	COG0523	cobalamin synthesis protein
HB789_RS08405	COG0246	Mannitol dehydrogenase
HB789_RS08410	COG1312	Catalyzes the dehydration of D-mannonate
HB789_RS08435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS08435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS08440	COG1105	Belongs to the carbohydrate kinase PfkB family
HB789_RS08445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB789_RS08445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB789_RS08445	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HB789_RS08455	COG2855	membrane
HB789_RS08460	COG0583	DNA-binding transcription factor activity
HB789_RS08465	COG0833	amino acid
HB789_RS08475	COG4771	TonB-dependent receptor
HB789_RS08490	COG2311	Membrane
HB789_RS08505	COG1129	ABC transporter
HB789_RS08515	COG2949	membrane
HB789_RS08525	COG1346	cytolysis
HB789_RS08535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB789_RS08540	COG3659	wide pore channel activity
HB789_RS08555	COG2723	6-phospho-beta-galactosidase activity
HB789_RS08560	COG1538	Outer membrane efflux protein
HB789_RS08565	COG0586	Pfam SNARE associated Golgi protein
HB789_RS08575	COG1686	Belongs to the peptidase S11 family
HB789_RS08585	COG0277	FAD linked oxidase domain protein
HB789_RS08590	COG1472	Belongs to the glycosyl hydrolase 3 family
HB789_RS08595	COG1732	Glycine betaine
HB789_RS08600	COG1174	glycine betaine transport
HB789_RS08605	COG1125	glycine betaine transport
HB789_RS08610	COG1174	glycine betaine transport
HB789_RS08620	COG3275	phosphorelay sensor kinase activity
HB789_RS08630	COG4807	Protein conserved in bacteria
HB789_RS08650	COG5455	response to cobalt ion
HB789_RS08655	COG0583	DNA-binding transcription factor activity
HB789_RS08660	COG2252	PERMEase
HB789_RS08670	COG0583	DNA-binding transcription factor activity
HB789_RS08685	COG0351	phosphomethylpyrimidine kinase
HB789_RS08690	COG1830	Aldolase
HB789_RS08725	COG1070	Carbohydrate kinase
HB789_RS08735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB789_RS08740	COG4948	Mandelate Racemase Muconate Lactonizing
HB789_RS08745	COG0747	negative chemotaxis
HB789_RS08750	COG0601	transmembrane transport
HB789_RS08755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB789_RS08760	COG0444	Belongs to the ABC transporter superfamily
HB789_RS08765	COG4608	Belongs to the ABC transporter superfamily
HB789_RS08775	COG0826	peptidase U32
HB789_RS08780	COG0745	RESPONSE REGULATOR receiver
HB789_RS08785	COG2205	protein histidine kinase activity
HB789_RS08810	COG1301	dicarboxylic acid transport
HB789_RS08830	COG5002	protein histidine kinase activity
HB789_RS08835	COG0443	Heat shock 70 kDa protein
HB789_RS08840	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HB789_RS08855	COG2982	Protein involved in outer membrane biogenesis
HB789_RS08860	COG1253	flavin adenine dinucleotide binding
HB789_RS08935	COG0463	Glycosyl transferase, family 2
HB789_RS08950	COG2244	polysaccharide biosynthetic process
HB789_RS08960	COG1088	dTDP-glucose 4,6-dehydratase activity
HB789_RS08995	COG1088	dTDP-glucose 4,6-dehydratase activity
HB789_RS09065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HB789_RS09095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HB789_RS09100	COG0583	DNA-binding transcription factor activity
HB789_RS09110	COG0531	amino acid
HB789_RS09115	COG0640	Transcriptional regulator
HB789_RS09120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HB789_RS09125	COG2925	Exonuclease
HB789_RS09135	COG3344	reverse transcriptase
HB789_RS09145	COG1289	transmembrane transporter activity
HB789_RS09165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HB789_RS09175	COG1942	4-Oxalocrotonate Tautomerase
HB789_RS09180	COG0583	DNA-binding transcription factor activity
HB789_RS09185	COG0095	Lipoate-protein ligase
HB789_RS09190	COG0477	Major facilitator Superfamily
HB789_RS09200	COG3300	MHYT domain
HB789_RS09200	COG5001	Diguanylate cyclase
HB789_RS09210	COG3615	Tellurite resistance protein tehB
HB789_RS09235	COG3706	GGDEF domain
HB789_RS09285	COG2003	Belongs to the UPF0758 family
HB789_RS09330	COG3504	Conjugal transfer protein
HB789_RS09400	COG4771	TonB-dependent receptor
HB789_RS09405	COG1021	2,3-dihydroxybenzoate-AMP ligase
HB789_RS09425	COG3433	isochorismatase activity
HB789_RS09425	COG2226	methyltransferase
HB789_RS09425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB789_RS09440	COG1132	(ABC) transporter
HB789_RS09445	COG2814	Major facilitator Superfamily
HB789_RS09450	COG1169	isochorismate synthase
HB789_RS09455	COG0582	viral genome integration into host DNA
HB789_RS09465	COG0534	Mate efflux family protein
HB789_RS09475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HB789_RS09495	COG0604	alcohol dehydrogenase
HB789_RS09505	COG0025	NhaP-type Na H and K H
HB789_RS09550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB789_RS09560	COG1418	mRNA catabolic process
HB789_RS09565	COG0270	DNA (cytosine-5-)-methyltransferase activity
HB789_RS09570	COG3727	T/G mismatch-specific endonuclease activity
HB789_RS09575	COG0697	spore germination
HB789_RS09580	COG2354	Protein conserved in bacteria
HB789_RS09610	COG0366	Alpha amylase catalytic
HB789_RS09615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB789_RS09625	COG0765	amino acid transport
HB789_RS09630	COG1126	abc transporter atp-binding protein
HB789_RS09635	COG2197	response regulator
HB789_RS09645	COG2197	response regulator
HB789_RS09680	COG3318	Belongs to the UPF0149 family
HB789_RS09680	COG3012	SEC-C Motif Domain Protein
HB789_RS09685	COG0814	amino acid
HB789_RS09695	COG1528	Iron-storage protein
HB789_RS09710	COG0477	Major facilitator Superfamily
HB789_RS09720	COG2211	Major facilitator Superfamily
HB789_RS09730	COG1528	Iron-storage protein
HB789_RS09740	COG1879	ABC-type sugar transport system periplasmic component
HB789_RS09750	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS09775	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HB789_RS09785	COG3102	Protein conserved in bacteria
HB789_RS09805	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HB789_RS09810	COG1801	Protein of unknown function DUF72
HB789_RS09815	COG1335	isochorismatase
HB789_RS09825	COG0494	nUDIX hydrolase
HB789_RS09850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB789_RS09860	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HB789_RS09865	COG0739	heme binding
HB789_RS09870	COG1560	Kdo2-lipid A biosynthetic process
HB789_RS09880	COG1737	Transcriptional regulator
HB789_RS09890	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HB789_RS09895	COG0129	dihydroxy-acid dehydratase activity
HB789_RS09900	COG0800	Aldolase
HB789_RS09910	COG3141	response to X-ray
HB789_RS09915	COG2979	Protein of unknown function (DUF533)
HB789_RS09920	COG1770	oligopeptidase
HB789_RS09925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HB789_RS09935	COG2372	response to copper ion
HB789_RS09940	COG1276	copper resistance
HB789_RS09955	COG2990	Protein conserved in bacteria
HB789_RS09980	COG3008	intermembrane lipid transfer
HB789_RS09985	COG2995	paraquat-inducible protein a
HB789_RS09990	COG1956	GAF domain-containing protein
HB789_RS10010	COG2814	Major facilitator Superfamily
HB789_RS10015	COG1414	Transcriptional regulator
HB789_RS10045	COG0768	penicillin binding
HB789_RS10050	COG2226	methyltransferase
HB789_RS10065	COG3716	PTS system mannose fructose sorbose family IID component
HB789_RS10070	COG3715	PTS system
HB789_RS10075	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS10075	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB789_RS10080	COG1253	flavin adenine dinucleotide binding
HB789_RS10085	COG2200	EAL domain
HB789_RS10090	COG1760	l-serine dehydratase
HB789_RS10110	COG0251	oxidation-reduction process
HB789_RS10115	COG1199	ATP-dependent helicase activity
HB789_RS10125	COG3065	identical protein binding
HB789_RS10135	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HB789_RS10145	COG2894	cell division
HB789_RS10160	COG0179	Fumarylacetoacetate (FAA) hydrolase
HB789_RS10190	COG2719	SpoVR family
HB789_RS10215	COG1619	proteins homologs of microcin C7 resistance protein MccF
HB789_RS10225	COG4774	siderophore transport
HB789_RS10240	COG2308	Evidence 4 Homologs of previously reported genes of
HB789_RS10280	COG0583	DNA-binding transcription factor activity
HB789_RS10285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HB789_RS10300	COG1882	Formate acetyltransferase
HB789_RS10335	COG0583	DNA-binding transcription factor activity
HB789_RS10365	COG0583	DNA-binding transcription factor activity
HB789_RS10380	COG3122	Protein conserved in bacteria
HB789_RS10400	COG2885	chlorophyll binding
HB789_RS10535	COG0012	GTP binding
HB789_RS10555	COG0659	secondary active sulfate transmembrane transporter activity
HB789_RS10585	COG2890	protein-(glutamine-N5) methyltransferase activity
HB789_RS10605	COG0387	Pfam Sodium calcium exchanger
HB789_RS10610	COG4572	Cation transport regulator
HB789_RS10615	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HB789_RS10625	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HB789_RS10630	COG3707	response regulator
HB789_RS10635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB789_RS10645	COG1116	anion transmembrane transporter activity
HB789_RS10650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HB789_RS10650	COG2146	nitrite reductase [NAD(P)H] activity
HB789_RS10655	COG0243	molybdopterin cofactor binding
HB789_RS10660	COG4932	domain protein
HB789_RS10665	COG2197	response regulator
HB789_RS10670	COG3850	Histidine kinase
HB789_RS10675	COG2223	nitrite transmembrane transporter activity
HB789_RS10685	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HB789_RS10690	COG1140	nitrate reductase beta subunit
HB789_RS10695	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HB789_RS10700	COG2181	nitrate reductase activity
HB789_RS10710	COG1522	sequence-specific DNA binding
HB789_RS10745	COG0788	formyltetrahydrofolate deformylase activity
HB789_RS10755	COG1752	Esterase of the alpha-beta hydrolase superfamily
HB789_RS10760	COG0745	RESPONSE REGULATOR receiver
HB789_RS10765	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HB789_RS10770	COG2916	Histone family protein nucleoid-structuring protein H-NS
HB789_RS10780	COG1435	thymidine kinase activity
HB789_RS10785	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS10785	COG1454	alcohol dehydrogenase
HB789_RS10795	COG2095	MarC family integral membrane protein
HB789_RS10800	COG4166	transmembrane transport
HB789_RS10805	COG0601	transmembrane transport
HB789_RS10810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB789_RS10815	COG0444	Belongs to the ABC transporter superfamily
HB789_RS10825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB789_RS10845	COG2353	YceI-like domain
HB789_RS10855	COG2350	Protein conserved in bacteria
HB789_RS10865	COG3001	Fructosamine kinase
HB789_RS10875	COG1105	Belongs to the carbohydrate kinase PfkB family
HB789_RS10880	COG3137	Salt-induced outer membrane protein
HB789_RS10920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB789_RS10920	COG0072	phenylalanine-tRNA ligase activity
HB789_RS10940	COG0583	DNA-binding transcription factor activity
HB789_RS10960	COG0386	Belongs to the glutathione peroxidase family
HB789_RS10970	COG0791	NLP P60 protein
HB789_RS10980	COG4256	Hemin uptake protein
HB789_RS10985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB789_RS11000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HB789_RS11000	COG0574	Belongs to the PEP-utilizing enzyme family
HB789_RS11010	COG0628	permease
HB789_RS11015	COG0247	lactate metabolic process
HB789_RS11015	COG0277	FAD linked oxidase domain protein
HB789_RS11020	COG2050	protein possibly involved in aromatic compounds catabolism
HB789_RS11025	COG2261	transglycosylase associated protein
HB789_RS11050	COG1120	ATPase activity
HB789_RS11055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB789_RS11065	COG0583	DNA-binding transcription factor activity
HB789_RS11090	COG1304	FMN binding
HB789_RS11095	COG1309	transcriptional regulator
HB789_RS11115	COG0316	Belongs to the HesB IscA family
HB789_RS11120	COG0719	Fe-S assembly protein
HB789_RS11125	COG0396	ATPase activity
HB789_RS11130	COG0719	Fe-S assembly protein
HB789_RS11145	COG1376	ErfK ybiS ycfS ynhG family protein
HB789_RS11175	COG1309	transcriptional regulator
HB789_RS11180	COG1082	Xylose isomerase domain protein TIM barrel
HB789_RS11180	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HB789_RS11185	COG2271	Major facilitator Superfamily
HB789_RS11190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HB789_RS11200	COG1120	ATPase activity
HB789_RS11205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB789_RS11210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HB789_RS11215	COG1414	Transcriptional regulator
HB789_RS11250	COG2814	Major facilitator Superfamily
HB789_RS11270	COG0583	DNA-binding transcription factor activity
HB789_RS11275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HB789_RS11295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB789_RS11300	COG1116	anion transmembrane transporter activity
HB789_RS11305	COG4774	siderophore transport
HB789_RS11310	COG1120	ATPase activity
HB789_RS11315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB789_RS11320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB789_RS11340	COG0765	amino acid transport
HB789_RS11345	COG1126	abc transporter atp-binding protein
HB789_RS11385	COG3383	formate dehydrogenase (NAD+) activity
HB789_RS11390	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HB789_RS11400	COG1175	transmembrane transport
HB789_RS11430	COG4133	protoheme IX ABC transporter activity
HB789_RS11435	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HB789_RS11440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HB789_RS11455	COG1138	Cytochrome C-type biogenesis protein
HB789_RS11460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HB789_RS11465	COG4235	cytochrome complex assembly
HB789_RS11465	COG3088	subunit of a heme lyase
HB789_RS11485	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HB789_RS11520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB789_RS11555	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS11560	COG2610	gluconate transmembrane transporter activity
HB789_RS11565	COG1250	3-hydroxyacyl-CoA dehydrogenase
HB789_RS11575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HB789_RS11585	COG0583	DNA-binding transcription factor activity
HB789_RS11610	COG0277	FAD linked oxidase domain protein
HB789_RS11615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB789_RS11640	COG0402	S-adenosylhomocysteine deaminase activity
HB789_RS11685	COG0604	alcohol dehydrogenase
HB789_RS11685	COG3321	synthase
HB789_RS11685	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS11715	COG4608	Belongs to the ABC transporter superfamily
HB789_RS11720	COG0444	Belongs to the ABC transporter superfamily
HB789_RS11745	COG0346	lactoylglutathione lyase activity
HB789_RS11750	COG1349	DNA-binding transcription factor activity
HB789_RS11785	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HB789_RS11835	COG0307	riboflavin synthase, alpha
HB789_RS11840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB789_RS11845	COG2814	Major facilitator Superfamily
HB789_RS11850	COG0583	DNA-binding transcription factor activity
HB789_RS11865	COG2814	Major facilitator Superfamily
HB789_RS11880	COG0791	NLP P60 protein
HB789_RS11885	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HB789_RS11895	COG0346	lactoylglutathione lyase activity
HB789_RS11900	COG1902	pentaerythritol trinitrate reductase activity
HB789_RS11905	COG1309	transcriptional regulator
HB789_RS11910	COG3313	Fe-S protein
HB789_RS11915	COG4989	oxidoreductase activity
HB789_RS11920	COG2032	superoxide dismutase activity
HB789_RS11925	COG1289	transmembrane transporter activity
HB789_RS11930	COG1566	PFAM secretion protein HlyD family protein
HB789_RS11945	COG3706	GGDEF domain
HB789_RS11960	COG3895	Periplasmic Protein
HB789_RS11975	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HB789_RS11980	COG0625	glutathione transferase activity
HB789_RS11990	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HB789_RS12000	COG4659	FMN binding
HB789_RS12035	COG2723	6-phospho-beta-galactosidase activity
HB789_RS12045	COG0673	inositol 2-dehydrogenase activity
HB789_RS12055	COG2814	Major facilitator Superfamily
HB789_RS12075	COG3038	cytochrome b561
HB789_RS12095	COG0583	DNA-binding transcription factor activity
HB789_RS12100	COG3485	protocatechuate 3,4-dioxygenase
HB789_RS12105	COG3485	protocatechuate 3,4-dioxygenase
HB789_RS12110	COG5383	Protein conserved in bacteria
HB789_RS12115	COG2272	Belongs to the type-B carboxylesterase lipase family
HB789_RS12130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB789_RS12135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HB789_RS12140	COG1275	C4-dicarboxylate transporter malic acid transport protein
HB789_RS12145	COG0500	methyltransferase
HB789_RS12160	COG2207	Transcriptional regulator
HB789_RS12160	COG3708	Transcriptional regulator
HB789_RS12165	COG3135	benzoate transporter
HB789_RS12170	COG1396	sequence-specific DNA binding
HB789_RS12180	COG0826	peptidase U32
HB789_RS12200	COG1294	oxidase, subunit
HB789_RS12205	COG1271	oxidase subunit
HB789_RS12210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB789_RS12215	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HB789_RS12220	COG3842	ATPase activity
HB789_RS12225	COG1176	ABC-type spermidine putrescine transport system, permease component I
HB789_RS12230	COG1177	transmembrane transport
HB789_RS12235	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS12270	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS12275	COG0747	negative chemotaxis
HB789_RS12285	COG3238	Protein conserved in bacteria
HB789_RS12290	COG1247	-acetyltransferase
HB789_RS12300	COG2130	NADP-dependent
HB789_RS12315	COG3691	Protein conserved in bacteria
HB789_RS12320	COG1228	amidohydrolase
HB789_RS12325	COG4772	TonB-dependent receptor
HB789_RS12350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HB789_RS12355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HB789_RS12360	COG1473	amidohydrolase
HB789_RS12365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HB789_RS12370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB789_RS12380	COG0765	amino acid transport
HB789_RS12385	COG1126	abc transporter atp-binding protein
HB789_RS12395	COG0625	glutathione transferase activity
HB789_RS12430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HB789_RS12435	COG3842	ATPase activity
HB789_RS12440	COG1840	ABC-type Fe3 transport system, periplasmic component
HB789_RS12445	COG1178	ABC-type Fe3 transport system permease component
HB789_RS12450	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HB789_RS12455	COG2181	nitrate reductase activity
HB789_RS12460	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HB789_RS12465	COG1140	nitrate reductase beta subunit
HB789_RS12470	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HB789_RS12490	COG1414	Transcriptional regulator
HB789_RS12495	COG4948	Mandelate Racemase Muconate Lactonizing
HB789_RS12500	COG4829	muconolactone delta-isomerase
HB789_RS12505	COG3485	protocatechuate 3,4-dioxygenase
HB789_RS12515	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HB789_RS12540	COG0437	4 iron, 4 sulfur cluster binding
HB789_RS12545	COG2864	formate dehydrogenase
HB789_RS12560	COG2326	polyphosphate kinase activity
HB789_RS12570	COG2814	Major facilitator Superfamily
HB789_RS12580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HB789_RS12590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB789_RS12600	COG0747	negative chemotaxis
HB789_RS12605	COG1064	alcohol dehydrogenase
HB789_RS12620	COG0488	(ABC) transporter
HB789_RS12665	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS12670	COG3729	General stress protein
HB789_RS12680	COG3685	Protein conserved in bacteria
HB789_RS12690	COG0366	Alpha amylase catalytic
HB789_RS12700	COG2323	membrane
HB789_RS12710	COG3111	PFAM Bacterial OB fold (BOF) protein
HB789_RS12720	COG1764	response to oxidative stress
HB789_RS12745	COG3781	membrane
HB789_RS12750	COG0243	molybdopterin cofactor binding
HB789_RS12755	COG0583	DNA-binding transcription factor activity
HB789_RS12760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS12790	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS12795	COG1447	Phosphotransferase system cellobiose-specific component IIA
HB789_RS12800	COG2814	Major facilitator Superfamily
HB789_RS12805	COG1285	pathogenesis
HB789_RS12810	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HB789_RS12820	COG0583	DNA-binding transcription factor activity
HB789_RS12840	COG0519	Catalyzes the synthesis of GMP from XMP
HB789_RS12840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HB789_RS12880	COG0596	Alpha beta hydrolase
HB789_RS12890	COG2205	protein histidine kinase activity
HB789_RS12905	COG0076	glutamate decarboxylase activity
HB789_RS12910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HB789_RS12915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB789_RS12920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB789_RS12925	COG1116	anion transmembrane transporter activity
HB789_RS12930	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HB789_RS12945	COG0673	inositol 2-dehydrogenase activity
HB789_RS12955	COG1609	Transcriptional regulator
HB789_RS12960	COG3706	GGDEF domain
HB789_RS12965	COG0402	S-adenosylhomocysteine deaminase activity
HB789_RS12970	COG1953	Uracil, thiamine, allantoin
HB789_RS13010	COG0406	alpha-ribazole phosphatase activity
HB789_RS13015	COG1335	isochorismatase
HB789_RS13045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HB789_RS13115	COG0765	amino acid transport
HB789_RS13125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HB789_RS13135	COG2070	2-Nitropropane dioxygenase
HB789_RS13140	COG0583	DNA-binding transcription factor activity
HB789_RS13150	COG1902	pentaerythritol trinitrate reductase activity
HB789_RS13155	COG4529	Protein conserved in bacteria
HB789_RS13160	COG0477	Major facilitator Superfamily
HB789_RS13190	COG2223	nitrite transmembrane transporter activity
HB789_RS13200	COG1609	Transcriptional regulator
HB789_RS13205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS13220	COG3037	sugar-specific permease SgaT UlaA
HB789_RS13225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HB789_RS13235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB789_RS13240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB789_RS13240	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HB789_RS13240	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB789_RS13255	COG0583	DNA-binding transcription factor activity
HB789_RS13260	COG0583	DNA-binding transcription factor activity
HB789_RS13265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HB789_RS13275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HB789_RS13290	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS13300	COG1609	Transcriptional regulator
HB789_RS13330	COG1652	LysM domain
HB789_RS13345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HB789_RS13345	COG0426	domain, Protein
HB789_RS13370	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HB789_RS13370	COG0456	acetyltransferase
HB789_RS13380	COG0667	Aldo Keto reductase
HB789_RS13385	COG0667	Aldo Keto reductase
HB789_RS13395	COG0667	Aldo Keto reductase
HB789_RS13415	COG4977	sequence-specific DNA binding
HB789_RS13435	COG4977	sequence-specific DNA binding
HB789_RS13440	COG1349	DNA-binding transcription factor activity
HB789_RS13455	COG1349	DNA-binding transcription factor activity
HB789_RS13460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HB789_RS13465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB789_RS13470	COG0738	Major facilitator superfamily
HB789_RS13515	COG1929	Belongs to the glycerate kinase type-1 family
HB789_RS13520	COG3835	regulator
HB789_RS13540	COG2186	Transcriptional regulator
HB789_RS13545	COG1263	PTS System
HB789_RS13545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB789_RS13555	COG2814	Major facilitator Superfamily
HB789_RS13560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS13560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS13575	COG2819	hydrolase of the alpha beta superfamily
HB789_RS13580	COG5001	Diguanylate cyclase
HB789_RS13580	COG3300	MHYT domain
HB789_RS13615	COG3188	usher protein
HB789_RS13625	COG1649	PFAM Uncharacterised BCR, COG1649
HB789_RS13630	COG3550	peptidyl-serine autophosphorylation
HB789_RS13635	COG1396	sequence-specific DNA binding
HB789_RS13640	COG2351	hydroxyisourate hydrolase activity
HB789_RS13645	COG3195	allantoin biosynthetic process
HB789_RS13645	COG3648	Uricase
HB789_RS13650	COG2233	PERMEase
HB789_RS13680	COG2207	Transcriptional regulator
HB789_RS13695	COG4628	conserved protein (DUF2132)
HB789_RS13715	COG2011	ABC-type metal ion transport system permease component
HB789_RS13720	COG2070	2-Nitropropane dioxygenase
HB789_RS13730	COG0477	Major facilitator Superfamily
HB789_RS13800	COG2199	diguanylate cyclase activity
HB789_RS13815	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS13820	COG0583	DNA-binding transcription factor activity
HB789_RS13830	COG0039	L-malate dehydrogenase activity
HB789_RS13835	COG1349	DNA-binding transcription factor activity
HB789_RS13840	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HB789_RS13845	COG3395	kinase activity
HB789_RS13855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HB789_RS13870	COG2731	YhcH YjgK YiaL family protein
HB789_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS13905	COG4977	sequence-specific DNA binding
HB789_RS13915	COG0697	spore germination
HB789_RS13920	COG2814	Major facilitator Superfamily
HB789_RS13930	COG0410	ABC transporter
HB789_RS13935	COG1129	ABC transporter
HB789_RS13950	COG0683	leucine binding
HB789_RS13955	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HB789_RS13990	COG2223	nitrite transmembrane transporter activity
HB789_RS13995	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HB789_RS14010	COG1349	DNA-binding transcription factor activity
HB789_RS14015	COG2084	Dehydrogenase
HB789_RS14020	COG3395	kinase activity
HB789_RS14025	COG0235	Class ii aldolase
HB789_RS14030	COG3622	Belongs to the hyi family
HB789_RS14035	COG2610	gluconate transmembrane transporter activity
HB789_RS14040	COG2207	Transcriptional regulator
HB789_RS14040	COG3708	Transcriptional regulator
HB789_RS14065	COG2200	EAL domain
HB789_RS14070	COG1546	Belongs to the CinA family
HB789_RS14075	COG0071	Belongs to the small heat shock protein (HSP20) family
HB789_RS14090	COG2197	response regulator
HB789_RS14095	COG3039	Transposase
HB789_RS14110	COG2135	peptidase activity
HB789_RS14115	COG2207	Transcriptional regulator
HB789_RS14130	COG4221	oxidoreductase activity
HB789_RS14135	COG1802	Transcriptional regulator
HB789_RS14140	COG0589	response to stress
HB789_RS14145	COG0246	Mannitol dehydrogenase
HB789_RS14150	COG2271	Major facilitator Superfamily
HB789_RS14165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB789_RS14195	COG0437	4 iron, 4 sulfur cluster binding
HB789_RS14200	COG3302	dmso reductase anchor subunit
HB789_RS14215	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HB789_RS14220	COG1940	carbohydrate kinase activity
HB789_RS14225	COG0583	DNA-binding transcription factor activity
HB789_RS14230	COG2814	Major facilitator Superfamily
HB789_RS14235	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HB789_RS14245	COG3591	Belongs to the peptidase S1B family
HB789_RS14265	COG0628	permease
HB789_RS14295	COG0679	Auxin Efflux Carrier
HB789_RS14305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HB789_RS14330	COG3290	protein histidine kinase activity
HB789_RS14335	COG4565	transcriptional regulatory protein
HB789_RS14355	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HB789_RS14355	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HB789_RS14365	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HB789_RS14370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HB789_RS14380	COG0183	Belongs to the thiolase family
HB789_RS14385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HB789_RS14395	COG1414	Transcriptional regulator
HB789_RS14400	COG2840	Smr protein MutS2
HB789_RS14405	COG0583	DNA-binding transcription factor activity
HB789_RS14415	COG1473	amidohydrolase
HB789_RS14420	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HB789_RS14435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB789_RS14450	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HB789_RS14455	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HB789_RS14470	COG0531	amino acid
HB789_RS14480	COG3136	membrane protein required for alginate biosynthesis
HB789_RS14485	COG0745	RESPONSE REGULATOR receiver
HB789_RS14495	COG2205	protein histidine kinase activity
HB789_RS14505	COG0114	fumarate hydratase activity
HB789_RS14510	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HB789_RS14510	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HB789_RS14515	COG1482	cell wall glycoprotein biosynthetic process
HB789_RS14520	COG5339	Protein conserved in bacteria
HB789_RS14525	COG1609	Transcriptional regulator
HB789_RS14530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB789_RS14530	COG1263	PTS System
HB789_RS14535	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HB789_RS14560	COG2391	methyltransferase activity
HB789_RS14565	COG0425	Belongs to the sulfur carrier protein TusA family
HB789_RS14570	COG5562	phage envelope protein
HB789_RS14575	COG0401	homolog of Blt101
HB789_RS14580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB789_RS14585	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS14595	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB789_RS14600	COG0477	Major facilitator Superfamily
HB789_RS14605	COG1113	amino acid transport
HB789_RS14610	COG2988	succinylglutamate desuccinylase activity
HB789_RS14615	COG3724	N-succinylarginine dihydrolase activity
HB789_RS14620	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS14625	COG3138	arginine N-succinyltransferase
HB789_RS14630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HB789_RS14640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HB789_RS14645	COG0667	Aldo Keto reductase
HB789_RS14650	COG0583	DNA-binding transcription factor activity
HB789_RS14675	COG4122	O-methyltransferase activity
HB789_RS14680	COG1643	Atp-dependent helicase
HB789_RS14695	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HB789_RS14700	COG3327	negative regulation of DNA-templated transcription, initiation
HB789_RS14705	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HB789_RS14710	COG0183	Belongs to the thiolase family
HB789_RS14715	COG2050	protein possibly involved in aromatic compounds catabolism
HB789_RS14720	COG1250	3-hydroxyacyl-CoA dehydrogenase
HB789_RS14725	COG1024	Enoyl-CoA hydratase
HB789_RS14730	COG1024	Enoyl-CoA hydratase
HB789_RS14735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB789_RS14740	COG2151	metal-sulfur cluster biosynthetic enzyme
HB789_RS14745	COG3396	Phenylacetate-CoA oxygenase
HB789_RS14750	COG3460	Phenylacetate-CoA oxygenase
HB789_RS14755	COG3396	Phenylacetate-CoA oxygenase
HB789_RS14760	COG2030	dehydratase
HB789_RS14760	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS14780	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS14785	COG2207	Transcriptional regulator
HB789_RS14790	COG3784	Protein of unknown function (DUF1318)
HB789_RS14800	COG2911	Protein conserved in bacteria
HB789_RS14805	COG0586	Pfam SNARE associated Golgi protein
HB789_RS14810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB789_RS14815	COG3187	Heat shock protein
HB789_RS14820	COG3042	response to heat
HB789_RS14825	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HB789_RS14825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HB789_RS14825	COG1013	pyruvate-flavodoxin oxidoreductase activity
HB789_RS14825	COG0674	pyruvate-flavodoxin oxidoreductase activity
HB789_RS14830	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB789_RS14840	COG0589	response to stress
HB789_RS14850	COG0513	Belongs to the DEAD box helicase family
HB789_RS14860	COG1349	DNA-binding transcription factor activity
HB789_RS14865	COG0673	inositol 2-dehydrogenase activity
HB789_RS14880	COG1113	amino acid transport
HB789_RS14885	COG1522	sequence-specific DNA binding
HB789_RS14895	COG1448	Aminotransferase
HB789_RS14900	COG2011	ABC-type metal ion transport system permease component
HB789_RS14915	COG0436	Aminotransferase
HB789_RS14920	COG0604	alcohol dehydrogenase
HB789_RS14950	COG0583	DNA-binding transcription factor activity
HB789_RS14970	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS14975	COG1309	transcriptional regulator
HB789_RS14980	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS15075	COG2885	chlorophyll binding
HB789_RS15200	COG0741	lytic transglycosylase activity
HB789_RS15200	COG0739	heme binding
HB789_RS15200	COG1196	nuclear chromosome segregation
HB789_RS15270	COG3567	Phage-associated protein, HI1409 family
HB789_RS15275	COG1783	phage Terminase large subunit
HB789_RS15295	COG3772	lysozyme
HB789_RS15305	COG0484	heat shock protein binding
HB789_RS15410	COG0582	viral genome integration into host DNA
HB789_RS15415	COG0693	protein deglycase activity
HB789_RS15420	COG1078	dGTPase activity
HB789_RS15425	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS15430	COG0583	DNA-binding transcription factor activity
HB789_RS15450	COG0656	L-ascorbic acid biosynthetic process
HB789_RS15480	COG4166	transmembrane transport
HB789_RS15490	COG2866	Carboxypeptidase
HB789_RS15495	COG4948	Mandelate Racemase Muconate Lactonizing
HB789_RS15500	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HB789_RS15505	COG3180	Ammonia monooxygenase
HB789_RS15515	COG1486	melibiose metabolic process
HB789_RS15520	COG0583	DNA-binding transcription factor activity
HB789_RS15530	COG3106	COG3106 Predicted ATPase
HB789_RS15540	COG1983	PspC domain protein
HB789_RS15550	COG1842	Phage shock protein A
HB789_RS15555	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HB789_RS15565	COG1473	amidohydrolase
HB789_RS15580	COG0702	epimerase
HB789_RS15595	COG2135	peptidase activity
HB789_RS15605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HB789_RS15610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HB789_RS15615	COG3344	reverse transcriptase
HB789_RS15660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HB789_RS15685	COG3039	Transposase
HB789_RS15780	COG4171	peptide transport system, permease
HB789_RS15795	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HB789_RS15805	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HB789_RS15810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HB789_RS15810	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HB789_RS15825	COG1349	DNA-binding transcription factor activity
HB789_RS15835	COG0023	Translation Initiation Factor
HB789_RS15845	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HB789_RS15850	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HB789_RS15855	COG0671	phosphoesterase, PA-phosphatase related
HB789_RS15865	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HB789_RS15890	COG0616	signal peptide processing
HB789_RS15900	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS15905	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HB789_RS15915	COG0583	DNA-binding transcription factor activity
HB789_RS15925	COG0009	L-threonylcarbamoyladenylate synthase
HB789_RS15935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HB789_RS15940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HB789_RS15940	COG0512	Glutamine amidotransferase of anthranilate synthase
HB789_RS15945	COG0135	phosphoribosylanthranilate isomerase activity
HB789_RS15945	COG0134	indole-3-glycerol-phosphate synthase activity
HB789_RS16000	COG4774	siderophore transport
HB789_RS16010	COG3047	cAMP biosynthetic process
HB789_RS16015	COG0727	PFAM Uncharacterised protein family (UPF0153)
HB789_RS16045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB789_RS16050	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS16055	COG1988	membrane-bound metal-dependent
HB789_RS16060	COG1823	symporter activity
HB789_RS16070	COG0753	catalase activity
HB789_RS16095	COG2169	Transcriptional regulator
HB789_RS16095	COG1917	Cupin 2, conserved barrel domain protein
HB789_RS16100	COG1447	Phosphotransferase system cellobiose-specific component IIA
HB789_RS16105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS16115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS16120	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB789_RS16130	COG0322	excinuclease ABC activity
HB789_RS16135	COG3678	ATP-independent chaperone mediated protein folding
HB789_RS16145	COG3724	N-succinylarginine dihydrolase activity
HB789_RS16155	COG3138	arginine N-succinyltransferase
HB789_RS16165	COG0708	Exodeoxyribonuclease III
HB789_RS16170	COG0398	Pfam SNARE associated Golgi protein
HB789_RS16175	COG0398	Pfam SNARE associated Golgi protein
HB789_RS16180	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HB789_RS16185	COG4134	Bacterial extracellular solute-binding protein
HB789_RS16190	COG4135	transport system, permease component
HB789_RS16195	COG4136	ATPase activity
HB789_RS16200	COG2897	thiosulfate sulfurtransferase activity
HB789_RS16205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HB789_RS16210	COG0494	nUDIX hydrolase
HB789_RS16215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HB789_RS16220	COG0604	alcohol dehydrogenase
HB789_RS16220	COG3321	synthase
HB789_RS16220	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS16225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB789_RS16230	COG0709	Synthesizes selenophosphate from selenide and ATP
HB789_RS16245	COG0778	Nitroreductase
HB789_RS16250	COG0616	signal peptide processing
HB789_RS16255	COG0252	asparaginase activity
HB789_RS16260	COG1335	isochorismatase
HB789_RS16265	COG2814	Major facilitator Superfamily
HB789_RS16270	COG1349	DNA-binding transcription factor activity
HB789_RS16275	COG0667	Aldo Keto reductase
HB789_RS16280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB789_RS16285	COG0191	fructose-bisphosphate aldolase activity
HB789_RS16290	COG1063	alcohol dehydrogenase
HB789_RS16295	COG2271	Major facilitator Superfamily
HB789_RS16300	COG1063	alcohol dehydrogenase
HB789_RS16315	COG3139	Protein of unknown function (DUF1315)
HB789_RS16340	COG3713	MltA-interacting MipA family protein
HB789_RS16345	COG2766	serine protein kinase
HB789_RS16360	COG0386	Belongs to the glutathione peroxidase family
HB789_RS16385	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS16390	COG0583	DNA-binding transcription factor activity
HB789_RS16395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HB789_RS16400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HB789_RS16405	COG3344	reverse transcriptase
HB789_RS16415	COG0859	PFAM glycosyl transferase family 9
HB789_RS16420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HB789_RS16430	COG2207	Transcriptional regulator
HB789_RS16435	COG2807	transmembrane transport
HB789_RS16440	COG0504	CTP synthase activity
HB789_RS16445	COG1683	Conserved Protein
HB789_RS16450	COG3189	MarR family transcriptional regulator
HB789_RS16455	COG3042	response to heat
HB789_RS16460	COG2199	diguanylate cyclase activity
HB789_RS16460	COG2203	Gaf domain
HB789_RS16480	COG3182	Iron-regulated membrane protein
HB789_RS16490	COG1560	Kdo2-lipid A biosynthetic process
HB789_RS16500	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HB789_RS16505	COG3706	GGDEF domain
HB789_RS16510	COG0583	DNA-binding transcription factor activity
HB789_RS16515	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HB789_RS16545	COG1294	oxidase, subunit
HB789_RS16550	COG1271	oxidase subunit
HB789_RS16555	COG3546	catalase activity
HB789_RS16560	COG3685	Protein conserved in bacteria
HB789_RS16565	COG3685	Protein conserved in bacteria
HB789_RS16570	COG3729	General stress protein
HB789_RS16575	COG1063	alcohol dehydrogenase
HB789_RS16580	COG3813	Protein conserved in bacteria
HB789_RS16600	COG0640	Transcriptional regulator
HB789_RS16605	COG0538	isocitrate dehydrogenase activity
HB789_RS16690	COG0616	signal peptide processing
HB789_RS16705	COG4626	Terminase
HB789_RS16705	COG1802	Transcriptional regulator
HB789_RS16750	COG3772	lysozyme
HB789_RS16775	COG1403	HNH endonuclease
HB789_RS16795	COG3344	reverse transcriptase
HB789_RS16800	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HB789_RS16840	COG1396	sequence-specific DNA binding
HB789_RS16860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HB789_RS16870	COG0582	viral genome integration into host DNA
HB789_RS16875	COG0538	isocitrate dehydrogenase activity
HB789_RS16880	COG1187	pseudouridine synthase activity
HB789_RS16900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HB789_RS16920	COG2205	protein histidine kinase activity
HB789_RS16925	COG2850	peptidyl-arginine hydroxylation
HB789_RS16945	COG1177	transmembrane transport
HB789_RS16960	COG0318	PFAM AMP-dependent synthetase and ligase
HB789_RS16970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HB789_RS16980	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB789_RS16990	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB789_RS17000	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HB789_RS17005	COG1388	LysM domain
HB789_RS17005	COG1376	ErfK ybiS ycfS ynhG family protein
HB789_RS17020	COG1309	transcriptional regulator
HB789_RS17035	COG3134	Outer membrane lipoprotein
HB789_RS17040	COG1252	NADH dehydrogenase
HB789_RS17065	COG5633	Lipoprotein
HB789_RS17070	COG0537	adenosine 5'-monophosphoramidase activity
HB789_RS17080	COG0084	hydrolase, TatD family'
HB789_RS17085	COG0470	DNA polymerase III
HB789_RS17095	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HB789_RS17100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HB789_RS17105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HB789_RS17120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HB789_RS17140	COG1399	metal-binding, possibly nucleic acid-binding protein
HB789_RS17160	COG1530	ribonuclease E activity
HB789_RS17165	COG0583	DNA-binding transcription factor activity
HB789_RS17170	COG2814	Major facilitator Superfamily
HB789_RS17190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB789_RS17235	COG1560	Kdo2-lipid A biosynthetic process
HB789_RS17250	COG5645	(Lipo)protein
HB789_RS17285	COG3381	protein complex oligomerization
HB789_RS17310	COG0583	DNA-binding transcription factor activity
HB789_RS17320	COG1335	isochorismatase
HB789_RS17330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB789_RS17335	COG1702	phosphate starvation-inducible protein PhoH
HB789_RS17355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB789_RS17365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HB789_RS17380	COG1309	transcriptional regulator
HB789_RS17415	COG2233	PERMEase
HB789_RS17425	COG3729	General stress protein
HB789_RS17455	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS17470	COG0531	amino acid
HB789_RS17475	COG0174	glutamine synthetase
HB789_RS17480	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HB789_RS17485	COG1396	sequence-specific DNA binding
HB789_RS17485	COG1917	Cupin 2, conserved barrel domain protein
HB789_RS17490	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS17495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB789_RS17500	COG0583	DNA-binding transcription factor activity
HB789_RS17505	COG0473	3-isopropylmalate dehydrogenase activity
HB789_RS17510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB789_RS17515	COG4638	Rieske (2fe-2S)
HB789_RS17520	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS17525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB789_RS17550	COG0670	Belongs to the BI1 family
HB789_RS17565	COG2207	Transcriptional regulator
HB789_RS17570	COG1881	PFAM PEBP family protein
HB789_RS17585	COG1832	CoA-binding protein
HB789_RS17595	COG0210	DNA helicase
HB789_RS17600	COG3304	Inner membrane component domain
HB789_RS17605	COG1289	transmembrane transporter activity
HB789_RS17610	COG3070	regulator of competence-specific genes
HB789_RS17630	COG1067	ATP-dependent peptidase activity
HB789_RS17640	COG3130	regulation of translation
HB789_RS17645	COG3009	Protein conserved in bacteria
HB789_RS17650	COG3008	intermembrane lipid transfer
HB789_RS17650	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB789_RS17655	COG2995	paraquat-inducible protein a
HB789_RS17660	COG0488	(ABC) transporter
HB789_RS17670	COG0633	Ferredoxin
HB789_RS17670	COG3217	Mosc domain protein beta barrel domain protein
HB789_RS17685	COG0431	NADPH-dependent FMN reductase
HB789_RS17690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB789_RS17695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HB789_RS17700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB789_RS17710	COG0308	aminopeptidase N
HB789_RS17720	COG1473	amidohydrolase
HB789_RS17730	COG0814	amino acid
HB789_RS17755	COG1448	Aminotransferase
HB789_RS17760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HB789_RS17765	COG3108	Peptidase M15
HB789_RS17770	COG2989	Protein conserved in bacteria
HB789_RS17780	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HB789_RS17790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB789_RS17795	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB789_RS17800	COG3173	Aminoglycoside phosphotransferase
HB789_RS17815	COG3214	Protein conserved in bacteria
HB789_RS17830	COG2333	competence protein COMEC
HB789_RS17830	COG0658	competence protein
HB789_RS17840	COG0539	negative regulation of cytoplasmic translation
HB789_RS17860	COG2323	membrane
HB789_RS17865	COG1944	ATP diphosphatase activity
HB789_RS17870	COG2116	formate transmembrane transporter activity
HB789_RS17875	COG1882	Formate acetyltransferase
HB789_RS17880	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HB789_RS17885	COG0477	Major facilitator Superfamily
HB789_RS17890	COG3302	dmso reductase anchor subunit
HB789_RS17895	COG0437	4 iron, 4 sulfur cluster binding
HB789_RS17900	COG0243	molybdopterin cofactor binding
HB789_RS17910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HB789_RS17920	COG1674	ftsk spoiiie
HB789_RS17920	COG1178	ABC-type Fe3 transport system permease component
HB789_RS17930	COG0492	ferredoxin-NADP+ reductase activity
HB789_RS17935	COG4988	ABC transporter
HB789_RS17940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HB789_RS17955	COG0542	response to heat
HB789_RS17965	COG1278	Cold shock
HB789_RS17975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB789_RS17980	COG3593	DNA synthesis involved in DNA repair
HB789_RS17990	COG2431	L-lysine efflux transmembrane transporter activity
HB789_RS18000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB789_RS18010	COG0028	Belongs to the TPP enzyme family
HB789_RS18015	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HB789_RS18020	COG0702	epimerase
HB789_RS18025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HB789_RS18030	COG3023	N-Acetylmuramoyl-L-alanine amidase
HB789_RS18035	COG5001	Diguanylate cyclase
HB789_RS18035	COG4251	negative regulation of phosphorylation
HB789_RS18035	COG3706	GGDEF domain
HB789_RS18035	COG2203	Gaf domain
HB789_RS18045	COG1126	abc transporter atp-binding protein
HB789_RS18050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB789_RS18055	COG4215	(ABC) transporter
HB789_RS18060	COG4160	amino acid transport
HB789_RS18065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB789_RS18070	COG5002	protein histidine kinase activity
HB789_RS18075	COG0745	RESPONSE REGULATOR receiver
HB789_RS18090	COG1177	transmembrane transport
HB789_RS18095	COG1176	ABC-type spermidine putrescine transport system, permease component I
HB789_RS18100	COG3842	ATPase activity
HB789_RS18105	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HB789_RS18300	COG4695	Portal protein
HB789_RS18320	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HB789_RS18325	COG3226	Transcriptional regulator
HB789_RS18330	COG0738	Major facilitator superfamily
HB789_RS18335	COG0561	phosphatase activity
HB789_RS18340	COG2814	Major facilitator Superfamily
HB789_RS18345	COG0671	phosphoesterase, PA-phosphatase related
HB789_RS18350	COG1349	DNA-binding transcription factor activity
HB789_RS18355	COG1686	Belongs to the peptidase S11 family
HB789_RS18365	COG0625	glutathione transferase activity
HB789_RS18370	COG2133	pyrroloquinoline quinone binding
HB789_RS18380	COG2223	nitrite transmembrane transporter activity
HB789_RS18400	COG0747	negative chemotaxis
HB789_RS18415	COG0303	'Molybdopterin
HB789_RS18420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB789_RS18425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HB789_RS18430	COG1882	Formate acetyltransferase
HB789_RS18435	COG0561	phosphatase activity
HB789_RS18445	COG1609	Transcriptional regulator
HB789_RS18450	COG2271	Major facilitator Superfamily
HB789_RS18460	COG0488	(ABC) transporter
HB789_RS18465	COG2365	Tyrosine phosphatase family
HB789_RS18470	COG1376	ErfK ybiS ycfS ynhG family protein
HB789_RS18475	COG2188	Transcriptional regulator
HB789_RS18480	COG2723	6-phospho-beta-galactosidase activity
HB789_RS18485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HB789_RS18490	COG1321	iron dependent repressor
HB789_RS18500	COG2194	sulfuric ester hydrolase activity
HB789_RS18505	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HB789_RS18520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB789_RS18525	COG0765	amino acid transport
HB789_RS18530	COG1126	abc transporter atp-binding protein
HB789_RS18535	COG0668	transmembrane transport
HB789_RS18545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HB789_RS18555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HB789_RS18565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HB789_RS18570	COG1199	ATP-dependent helicase activity
HB789_RS18575	COG0513	Belongs to the DEAD box helicase family
HB789_RS18580	COG3958	Transketolase
HB789_RS18585	COG3959	Transketolase, thiamine diphosphate binding domain
HB789_RS18590	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS18595	COG2271	Major facilitator Superfamily
HB789_RS18605	COG0583	DNA-binding transcription factor activity
HB789_RS18610	COG1309	transcriptional regulator
HB789_RS18615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB789_RS18620	COG1131	(ABC) transporter
HB789_RS18625	COG0842	Transport permease protein
HB789_RS18630	COG0842	Transport permease protein
HB789_RS18640	COG3568	Endonuclease Exonuclease Phosphatase
HB789_RS18645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HB789_RS18650	COG0392	lysyltransferase activity
HB789_RS18655	COG0670	Belongs to the BI1 family
HB789_RS18660	COG0314	molybdopterin synthase activity
HB789_RS18665	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HB789_RS18675	COG0521	Mo-molybdopterin cofactor biosynthetic process
HB789_RS18695	COG0745	RESPONSE REGULATOR receiver
HB789_RS18700	COG0642	Histidine kinase
HB789_RS18710	COG3344	reverse transcriptase
HB789_RS18730	COG2226	methyltransferase
HB789_RS18745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HB789_RS18750	COG1881	PFAM PEBP family protein
HB789_RS18790	COG4677	pectinesterase activity
HB789_RS18825	COG0789	Transcriptional regulator
HB789_RS18830	COG2200	EAL domain
HB789_RS18855	COG0561	phosphatase activity
HB789_RS18860	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HB789_RS18865	COG4149	molybdate abc transporter
HB789_RS18870	COG0725	ABC transporter, periplasmic molybdate-binding protein
HB789_RS18880	COG3585	molybdate ion transport
HB789_RS18880	COG2005	Transcriptional regulator
HB789_RS18885	COG1119	ATPase activity
HB789_RS18895	COG1085	galactose-1-phosphate uridylyltransferase
HB789_RS18905	COG2017	converts alpha-aldose to the beta-anomer
HB789_RS18915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB789_RS18930	COG3201	nicotinamide mononucleotide transporter
HB789_RS18935	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HB789_RS18975	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HB789_RS18980	COG2885	chlorophyll binding
HB789_RS18990	COG3064	Membrane
HB789_RS18995	COG0848	biopolymer transport protein
HB789_RS19000	COG0811	peptide transport
HB789_RS19005	COG0824	Thioesterase
HB789_RS19010	COG3790	cyd operon protein YbgE
HB789_RS19015	COG4890	Cyd operon protein YbgT
HB789_RS19020	COG1294	oxidase, subunit
HB789_RS19025	COG1271	oxidase subunit
HB789_RS19030	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HB789_RS19040	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB789_RS19045	COG0567	Dehydrogenase, E1 component
HB789_RS19050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HB789_RS19055	COG1053	succinate dehydrogenase
HB789_RS19060	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HB789_RS19065	COG2009	succinate dehydrogenase
HB789_RS19100	COG1984	allophanate hydrolase subunit 2
HB789_RS19105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HB789_RS19120	COG0415	Belongs to the DNA photolyase family
HB789_RS19150	COG2205	protein histidine kinase activity
HB789_RS19155	COG0745	RESPONSE REGULATOR receiver
HB789_RS19165	COG0033	Phosphoglucomutase
HB789_RS19175	COG0596	Alpha beta hydrolase
HB789_RS19190	COG0735	belongs to the Fur family
HB789_RS19230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HB789_RS19235	COG1940	carbohydrate kinase activity
HB789_RS19235	COG1846	Transcriptional regulator
HB789_RS19240	COG0647	UMP catabolic process
HB789_RS19245	COG0367	asparagine synthase
HB789_RS19285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB789_RS19295	COG1702	phosphate starvation-inducible protein PhoH
HB789_RS19305	COG4535	Mg2 and Co2 transporter CorC
HB789_RS19320	COG0765	amino acid transport
HB789_RS19325	COG0765	amino acid transport
HB789_RS19330	COG1126	abc transporter atp-binding protein
HB789_RS19350	COG2888	peptidyl-tyrosine sulfation
HB789_RS19365	COG1466	dna polymerase III delta subunit
HB789_RS19380	COG0799	negative regulation of ribosome biogenesis
HB789_RS19390	COG0768	penicillin binding
HB789_RS19395	COG0772	Belongs to the SEDS family
HB789_RS19400	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB789_RS19405	COG1686	Belongs to the peptidase S11 family
HB789_RS19420	COG0583	DNA-binding transcription factor activity
HB789_RS19435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HB789_RS19455	COG3069	C4-dicarboxylate transmembrane transporter activity
HB789_RS19460	COG3719	Belongs to the RNase T2 family
HB789_RS19465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB789_RS19485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB789_RS19490	COG0583	DNA-binding transcription factor activity
HB789_RS19495	COG3969	phosphoadenosine phosphosulfate
HB789_RS19500	COG1475	DNA binding
HB789_RS19505	COG0436	Aminotransferase
HB789_RS19530	COG1129	ABC transporter
HB789_RS19535	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS19540	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS19550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB789_RS19565	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HB789_RS19575	COG0402	S-adenosylhomocysteine deaminase activity
HB789_RS19585	COG0483	inositol monophosphate 1-phosphatase activity
HB789_RS19590	COG2271	Major facilitator Superfamily
HB789_RS19620	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS19625	COG1129	ABC transporter
HB789_RS19630	COG0371	Dehydrogenase
HB789_RS19635	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS19650	COG2879	small protein
HB789_RS19655	COG1966	Carbon starvation protein
HB789_RS19665	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS19670	COG1535	isochorismatase
HB789_RS19670	COG3433	isochorismatase activity
HB789_RS19675	COG1021	2,3-dihydroxybenzoate-AMP ligase
HB789_RS19680	COG1169	isochorismate synthase
HB789_RS19685	COG4592	Periplasmic binding protein
HB789_RS19695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB789_RS19700	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB789_RS19705	COG1120	ATPase activity
HB789_RS19710	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HB789_RS19710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB789_RS19715	COG3251	PFAM MbtH domain protein
HB789_RS19720	COG2382	esterase
HB789_RS19725	COG4771	TonB-dependent receptor
HB789_RS19730	COG2977	Belongs to the P-Pant transferase superfamily
HB789_RS19735	COG3958	Transketolase
HB789_RS19740	COG3959	Transketolase, thiamine diphosphate binding domain
HB789_RS19745	COG2390	Transcriptional regulator
HB789_RS19750	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HB789_RS19755	COG1879	ABC-type sugar transport system periplasmic component
HB789_RS19765	COG1129	ABC transporter
HB789_RS19770	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS19780	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS19790	COG0583	DNA-binding transcription factor activity
HB789_RS19795	COG0668	transmembrane transport
HB789_RS19805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB789_RS19830	COG0747	negative chemotaxis
HB789_RS19835	COG0601	transmembrane transport
HB789_RS19840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB789_RS19845	COG0444	Belongs to the ABC transporter superfamily
HB789_RS19850	COG4608	Belongs to the ABC transporter superfamily
HB789_RS19855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HB789_RS19860	COG4221	oxidoreductase activity
HB789_RS19870	COG4215	(ABC) transporter
HB789_RS19875	COG0765	amino acid transport
HB789_RS19880	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB789_RS19895	COG0697	spore germination
HB789_RS19905	COG3698	Phosphodiester glycosidase
HB789_RS19950	COG2315	Protein conserved in bacteria
HB789_RS19955	COG0778	Nitroreductase
HB789_RS19965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB789_RS19975	COG3716	PTS system mannose fructose sorbose family IID component
HB789_RS19980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HB789_RS19985	COG2222	sugar isomerase
HB789_RS19990	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HB789_RS19990	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HB789_RS20005	COG0477	Major facilitator Superfamily
HB789_RS20010	COG0668	transmembrane transport
HB789_RS20040	COG3188	usher protein
HB789_RS20055	COG2771	luxR family
HB789_RS20065	COG0673	inositol 2-dehydrogenase activity
HB789_RS20075	COG2211	Major facilitator Superfamily
HB789_RS20080	COG1113	amino acid transport
HB789_RS20095	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS20100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB789_RS20110	COG0531	amino acid
HB789_RS20155	COG0667	Aldo Keto reductase
HB789_RS20160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB789_RS20165	COG1473	amidohydrolase
HB789_RS20195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB789_RS20200	COG1120	ATPase activity
HB789_RS20205	COG1566	PFAM secretion protein HlyD family protein
HB789_RS20250	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS20255	COG1129	ABC transporter
HB789_RS20270	COG0673	inositol 2-dehydrogenase activity
HB789_RS20300	COG3104	oligopeptide transport
HB789_RS20305	COG1982	Orn Lys Arg decarboxylase major
HB789_RS20310	COG0531	amino acid
HB789_RS20315	COG3710	Transcriptional regulator
HB789_RS20325	COG1560	Kdo2-lipid A biosynthetic process
HB789_RS20340	COG3188	usher protein
HB789_RS20345	COG3121	Chaperone
HB789_RS20350	COG3539	Fimbrial protein
HB789_RS20400	COG2501	S4 domain
HB789_RS20410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HB789_RS20425	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HB789_RS20430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HB789_RS20450	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HB789_RS20455	COG4181	ATPase activity
HB789_RS20460	COG2755	lipolytic protein G-D-S-L family
HB789_RS20465	COG0300	oxidoreductase activity
HB789_RS20470	COG3118	belongs to the thioredoxin family
HB789_RS20475	COG0390	transport system, permease component
HB789_RS20480	COG4619	ABC transporter
HB789_RS20485	COG0330	HflC and HflK could
HB789_RS20490	COG1585	Membrane protein implicated in regulation of membrane protease activity
HB789_RS20505	COG3735	TraB family
HB789_RS20510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HB789_RS20520	COG2223	nitrite transmembrane transporter activity
HB789_RS20525	COG4651	solute:proton antiporter activity
HB789_RS20525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB789_RS20530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB789_RS20570	COG2832	Protein of unknown function (DUF454)
HB789_RS20575	COG3923	Primosomal replication protein n
HB789_RS20585	COG5464	transposase or invertase
HB789_RS20590	COG3264	Mechanosensitive ion channel
HB789_RS20590	COG1196	nuclear chromosome segregation
HB789_RS20610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB789_RS20615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB789_RS20630	COG0110	maltose O-acetyltransferase activity
HB789_RS20680	COG1874	Beta-galactosidase
HB789_RS20685	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HB789_RS20690	COG3833	ABC-type maltose transport systems, permease component
HB789_RS20695	COG1175	transmembrane transport
HB789_RS20700	COG2182	Extracellular solute-binding protein
HB789_RS20710	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HB789_RS20725	COG2364	Membrane
HB789_RS20755	COG3695	enzyme binding
HB789_RS20760	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HB789_RS20765	COG1946	Acyl-CoA thioesterase
HB789_RS20770	COG0004	ammonium transporteR
HB789_RS20775	COG0347	Belongs to the P(II) protein family
HB789_RS20780	COG1132	(ABC) transporter
HB789_RS20785	COG1132	(ABC) transporter
HB789_RS20790	COG1522	sequence-specific DNA binding
HB789_RS20805	COG4533	DNA binding
HB789_RS20815	COG0824	Thioesterase
HB789_RS20820	COG1555	photosystem II stabilization
HB789_RS20825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB789_RS20830	COG0776	regulation of translation
HB789_RS20835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HB789_RS20855	COG0271	Belongs to the BolA IbaG family
HB789_RS20860	COG3056	Lipoprotein
HB789_RS20865	COG2223	nitrite transmembrane transporter activity
HB789_RS20870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HB789_RS20875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HB789_RS20880	COG1845	cytochrome c oxidase, subunit III
HB789_RS20885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HB789_RS20900	COG1414	Transcriptional regulator
HB789_RS20905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HB789_RS20910	COG1053	succinate dehydrogenase
HB789_RS20920	COG1053	succinate dehydrogenase
HB789_RS20935	COG0673	inositol 2-dehydrogenase activity
HB789_RS20940	COG2814	Major facilitator Superfamily
HB789_RS20950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HB789_RS20955	COG0693	protein deglycase activity
HB789_RS20975	COG0142	geranyltranstransferase activity
HB789_RS20985	COG0667	Aldo Keto reductase
HB789_RS20990	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HB789_RS21010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB789_RS21010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB789_RS21020	COG4238	major outer membrane lipoprotein
HB789_RS21040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB789_RS21045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB789_RS21050	COG1862	Preprotein translocase
HB789_RS21075	COG0450	alkyl hydroperoxide reductase
HB789_RS21085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS21100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB789_RS21110	COG1228	amidohydrolase
HB789_RS21120	COG1335	isochorismatase
HB789_RS21125	COG0583	DNA-binding transcription factor activity
HB789_RS21130	COG0366	Alpha amylase catalytic
HB789_RS21155	COG0420	3'-5' exonuclease activity
HB789_RS21160	COG0419	ATPase involved in DNA repair
HB789_RS21165	COG1940	carbohydrate kinase activity
HB789_RS21180	COG4126	flavin adenine dinucleotide binding
HB789_RS21190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HB789_RS21195	COG3416	Protein conserved in bacteria
HB789_RS21205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HB789_RS21215	COG1785	Belongs to the alkaline phosphatase family
HB789_RS21255	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HB789_RS21260	COG1335	isochorismatase
HB789_RS21265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HB789_RS21270	COG0113	porphobilinogen synthase activity
HB789_RS21280	COG2175	clavaminate synthase activity
HB789_RS21285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB789_RS21290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HB789_RS21295	COG4521	taurine ABC transporter
HB789_RS21300	COG2040	homocysteine
HB789_RS21305	COG0833	amino acid
HB789_RS21320	COG4303	Ethanolamine ammonia lyase large subunit
HB789_RS21325	COG4302	ethanolamine ammonia-lyase activity
HB789_RS21365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB789_RS21370	COG1126	abc transporter atp-binding protein
HB789_RS21375	COG0765	amino acid transport
HB789_RS21380	COG0765	amino acid transport
HB789_RS21395	COG3188	usher protein
HB789_RS21420	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HB789_RS21430	COG3639	organic phosphonate transmembrane transporter activity
HB789_RS21450	COG0791	NLP P60 protein
HB789_RS21475	COG0582	viral genome integration into host DNA
HB789_RS21480	COG1192	Involved in chromosome partitioning
HB789_RS21540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HB789_RS21545	COG0022	dehydrogenase e1 component
HB789_RS21550	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB789_RS21555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB789_RS21575	COG1070	Carbohydrate kinase
HB789_RS21580	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS21585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB789_RS21590	COG3775	system Galactitol-specific IIC component
HB789_RS21595	COG0625	glutathione transferase activity
HB789_RS21600	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HB789_RS21615	COG0579	oxidoreductase
HB789_RS21620	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS21625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HB789_RS21630	COG1113	amino acid transport
HB789_RS21635	COG1802	Transcriptional regulator
HB789_RS21655	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB789_RS21660	COG0454	-acetyltransferase
HB789_RS21675	COG2991	Protein conserved in bacteria
HB789_RS21690	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB789_RS21695	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB789_RS21710	COG3034	peptidoglycan biosynthetic process
HB789_RS21715	COG0121	glutamine amidotransferase
HB789_RS21725	COG1960	acyl-CoA dehydrogenase activity
HB789_RS21730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HB789_RS21740	COG0583	DNA-binding transcription factor activity
HB789_RS21750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HB789_RS21760	COG2226	methyltransferase
HB789_RS21770	COG1388	LysM domain
HB789_RS21770	COG0741	lytic transglycosylase activity
HB789_RS21775	COG2226	methyltransferase
HB789_RS21785	COG2814	Major facilitator Superfamily
HB789_RS21790	COG0583	DNA-binding transcription factor activity
HB789_RS21795	COG0656	L-ascorbic acid biosynthetic process
HB789_RS21830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HB789_RS21840	COG2011	ABC-type metal ion transport system permease component
HB789_RS21845	COG1464	Belongs to the NlpA lipoprotein family
HB789_RS21855	COG1720	tRNA m6t6A37 methyltransferase activity
HB789_RS21865	COG0791	NLP P60 protein
HB789_RS21870	COG3015	lipoprotein NlpE involved in copper resistance
HB789_RS21875	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HB789_RS21890	COG4568	rho-dependent transcription termination
HB789_RS21900	COG0346	lactoylglutathione lyase activity
HB789_RS21905	COG1982	Orn Lys Arg decarboxylase major
HB789_RS21945	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HB789_RS21955	COG0750	zinc metalloprotease
HB789_RS21960	COG0575	Belongs to the CDS family
HB789_RS21970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HB789_RS21995	COG0024	Methionine aminopeptidase
HB789_RS22000	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HB789_RS22015	COG3835	regulator
HB789_RS22020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB789_RS22040	COG2860	membrane
HB789_RS22060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB789_RS22065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HB789_RS22070	COG1120	ATPase activity
HB789_RS22080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB789_RS22175	COG1643	Atp-dependent helicase
HB789_RS22180	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HB789_RS22200	COG0617	tRNA 3'-terminal CCA addition
HB789_RS22205	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HB789_RS22225	COG0726	polysaccharide deacetylase
HB789_RS22230	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS22235	COG0842	Transport permease protein
HB789_RS22240	COG1131	(ABC) transporter
HB789_RS22245	COG0288	reversible hydration of carbon dioxide
HB789_RS22260	COG4993	Dehydrogenase
HB789_RS22265	COG2132	Multicopper oxidase
HB789_RS22315	COG3064	Membrane
HB789_RS22330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB789_RS22335	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB789_RS22340	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HB789_RS22345	COG2186	Transcriptional regulator
HB789_RS22350	COG1113	amino acid transport
HB789_RS22355	COG2211	Major facilitator Superfamily
HB789_RS22360	COG3940	Belongs to the glycosyl hydrolase 43 family
HB789_RS22365	COG3725	Membrane protein required for beta-lactamase induction
HB789_RS22370	COG3023	N-Acetylmuramoyl-L-alanine amidase
HB789_RS22380	COG4969	Belongs to the N-Me-Phe pilin family
HB789_RS22385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB789_RS22390	COG1459	type II secretion system
HB789_RS22415	COG0494	nUDIX hydrolase
HB789_RS22435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HB789_RS22440	COG0849	cell division
HB789_RS22465	COG0772	Belongs to the SEDS family
HB789_RS22480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HB789_RS22485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HB789_RS22490	COG0768	penicillin binding
HB789_RS22510	COG1609	Transcriptional regulator
HB789_RS22520	COG0028	Belongs to the TPP enzyme family
HB789_RS22565	COG0738	Major facilitator superfamily
HB789_RS22575	COG0583	DNA-binding transcription factor activity
HB789_RS22580	COG2271	Major facilitator Superfamily
HB789_RS22585	COG2814	Major facilitator Superfamily
HB789_RS22605	COG1178	ABC-type Fe3 transport system permease component
HB789_RS22615	COG0586	Pfam SNARE associated Golgi protein
HB789_RS22635	COG0235	Class ii aldolase
HB789_RS22640	COG0417	DNA replication proofreading
HB789_RS22650	COG0564	pseudouridine synthase activity
HB789_RS22660	COG3493	citrate carrier protein
HB789_RS22675	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HB789_RS22680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HB789_RS22690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HB789_RS22735	COG0505	Belongs to the CarA family
HB789_RS22800	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HB789_RS22825	COG1047	Peptidyl-prolyl cis-trans
HB789_RS22840	COG0196	riboflavin kinase activity
HB789_RS22850	COG0583	DNA-binding transcription factor activity
HB789_RS22875	COG4735	regulation of single-species biofilm formation
HB789_RS22880	COG1584	GPR1 FUN34 yaaH family protein
HB789_RS22885	COG0477	Major facilitator Superfamily
HB789_RS22890	COG0521	Mo-molybdopterin cofactor biosynthetic process
HB789_RS22895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HB789_RS22900	COG1115	amino acid carrier protein
HB789_RS22915	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HB789_RS22925	COG0527	aspartate kinase activity
HB789_RS22925	COG0460	homoserine dehydrogenase
HB789_RS22935	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HB789_RS22945	COG0745	RESPONSE REGULATOR receiver
HB789_RS22950	COG4452	Inner membrane protein CreD
HB789_RS22955	COG2205	protein histidine kinase activity
HB789_RS22960	COG0745	RESPONSE REGULATOR receiver
HB789_RS22965	COG3045	CreA protein
HB789_RS22970	COG2207	Transcriptional regulator
HB789_RS22970	COG3708	Transcriptional regulator
HB789_RS22990	COG0741	lytic transglycosylase activity
HB789_RS22995	COG0488	(ABC) transporter
HB789_RS23005	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HB789_RS23010	COG0560	Phosphoserine phosphatase
HB789_RS23015	COG3726	membrane protein affecting hemolysin expression
HB789_RS23045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB789_RS23050	COG0084	hydrolase, TatD family'
HB789_RS23055	COG4667	esterase of the alpha-beta hydrolase superfamily
HB789_RS23065	COG2823	Periplasmic or secreted lipoprotein
HB789_RS23075	COG1011	Hydrolase
HB789_RS23080	COG0456	acetyltransferase
HB789_RS23085	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HB789_RS23120	COG3706	GGDEF domain
HB789_RS23125	COG4114	ferric iron reductase
HB789_RS23130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS23130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS23135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HB789_RS23140	COG2197	response regulator
HB789_RS23145	COG2197	response regulator
HB789_RS23160	COG2966	Psort location CytoplasmicMembrane, score
HB789_RS23175	COG1484	DNA-dependent DNA replication
HB789_RS23190	COG5464	transposase or invertase
HB789_RS23200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HB789_RS23205	COG3716	PTS system mannose fructose sorbose family IID component
HB789_RS23210	COG3715	PTS system
HB789_RS23225	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HB789_RS23225	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HB789_RS23235	COG1063	alcohol dehydrogenase
HB789_RS23240	COG1802	Transcriptional regulator
HB789_RS23245	COG2271	Major facilitator Superfamily
HB789_RS23250	COG1214	PFAM Peptidase M22, glycoprotease
HB789_RS23250	COG0456	acetyltransferase
HB789_RS23260	COG1737	Transcriptional regulator
HB789_RS23265	COG0800	Aldolase
HB789_RS23270	COG3734	2-keto-3-deoxy-galactonokinase
HB789_RS23285	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HB789_RS23315	COG1846	Transcriptional regulator
HB789_RS23325	COG0179	Fumarylacetoacetate (FAA) hydrolase
HB789_RS23335	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS23340	COG3384	dioxygenase
HB789_RS23350	COG3971	2-oxopent-4-enoate hydratase activity
HB789_RS23370	COG2368	4-hydroxyphenylacetate
HB789_RS23375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HB789_RS23390	COG1966	Carbon starvation protein
HB789_RS23395	COG2879	small protein
HB789_RS23400	COG0523	cobalamin synthesis protein
HB789_RS23410	COG1012	belongs to the aldehyde dehydrogenase family
HB789_RS23415	COG5464	transposase or invertase
HB789_RS23420	COG2207	Transcriptional regulator
HB789_RS23420	COG1917	Cupin 2, conserved barrel domain protein
HB789_RS23430	COG2733	membrane
HB789_RS23445	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HB789_RS23450	COG1924	4 iron, 4 sulfur cluster binding
HB789_RS23465	COG1566	PFAM secretion protein HlyD family protein
HB789_RS23475	COG5457	Domain of unknown function (DUF1127)
HB789_RS23480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB789_RS23490	COG0583	DNA-binding transcription factor activity
HB789_RS23495	COG2249	NAD(P)H dehydrogenase (quinone) activity
HB789_RS23505	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS23510	COG1129	ABC transporter
HB789_RS23515	COG1879	ABC-type sugar transport system periplasmic component
HB789_RS23525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB789_RS23530	COG0842	Transport permease protein
HB789_RS23530	COG1129	ABC transporter
HB789_RS23535	COG0842	Transport permease protein
HB789_RS23565	COG2850	peptidyl-arginine hydroxylation
HB789_RS23580	COG5002	protein histidine kinase activity
HB789_RS23585	COG0745	RESPONSE REGULATOR receiver
HB789_RS23590	COG1538	Outer membrane efflux protein
HB789_RS23595	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB789_RS23600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB789_RS23605	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB789_RS23615	COG3040	lipid binding
HB789_RS23620	COG0789	Transcriptional regulator
HB789_RS23630	COG0300	oxidoreductase activity
HB789_RS23645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB789_RS23665	COG3272	Protein of unknown function (DUF1722)
HB789_RS23670	COG4580	involved in the transport of maltose and maltodextrins
HB789_RS23680	COG2211	Major facilitator Superfamily
HB789_RS23685	COG3507	Belongs to the glycosyl hydrolase 43 family
HB789_RS23790	COG3039	Transposase
HB789_RS23800	COG0582	viral genome integration into host DNA
HB789_RS23810	COG0288	reversible hydration of carbon dioxide
HB789_RS23815	COG0659	secondary active sulfate transmembrane transporter activity
HB789_RS23820	COG1064	alcohol dehydrogenase
HB789_RS23825	COG1175	transmembrane transport
HB789_RS23830	COG0395	ABC-type sugar transport system, permease component
HB789_RS23835	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HB789_RS23840	COG3842	ATPase activity
HB789_RS23845	COG1653	transport
HB789_RS23855	COG1082	Xylose isomerase domain protein TIM barrel
HB789_RS23865	COG3962	Belongs to the TPP enzyme family
HB789_RS23870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB789_RS23875	COG1737	Transcriptional regulator
HB789_RS23875	COG0837	glucose binding
HB789_RS23880	COG3718	enzyme involved in inositol metabolism
HB789_RS23895	COG0433	COG0433 Predicted ATPase
HB789_RS23900	COG0795	lipopolysaccharide-transporting ATPase activity
HB789_RS23905	COG0795	lipopolysaccharide-transporting ATPase activity
HB789_RS23915	COG2927	DNA polymerase III (CHI subunit)
HB789_RS23920	COG0525	valine-tRNA ligase activity
HB789_RS23945	COG2188	Transcriptional regulator
HB789_RS23950	COG1288	antiporter activity
HB789_RS23955	COG1228	amidohydrolase
HB789_RS23960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB789_RS23965	COG2222	sugar isomerase
HB789_RS23970	COG2731	YhcH YjgK YiaL family protein
HB789_RS24005	COG1263	PTS System
HB789_RS24005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB789_RS24010	COG0366	Alpha amylase catalytic
HB789_RS24015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HB789_RS24020	COG1486	melibiose metabolic process
HB789_RS24045	COG0602	queuosine metabolic process
HB789_RS24050	COG2026	Addiction module toxin, RelE StbE family
HB789_RS24055	COG3077	Addiction module antitoxin, RelB DinJ family
HB789_RS24060	COG3711	transcriptional antiterminator
HB789_RS24060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB789_RS24065	COG2706	6-phosphogluconolactonase activity
HB789_RS24080	COG3964	amidohydrolase
HB789_RS24120	COG0312	modulator of DNA gyrase
HB789_RS24145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HB789_RS24155	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS24160	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS24165	COG1129	ABC transporter
HB789_RS24170	COG1879	ABC-type sugar transport system periplasmic component
HB789_RS24190	COG2105	PFAM AIG2 family protein
HB789_RS24195	COG2911	Protein conserved in bacteria
HB789_RS24200	COG0729	surface antigen
HB789_RS24210	COG1253	flavin adenine dinucleotide binding
HB789_RS24225	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HB789_RS24240	COG1733	regulation of RNA biosynthetic process
HB789_RS24245	COG0702	epimerase
HB789_RS24255	COG0697	spore germination
HB789_RS24265	COG1113	amino acid transport
HB789_RS24270	COG0545	Peptidyl-prolyl cis-trans isomerase
HB789_RS24275	COG3061	Opacity-associated protein A
HB789_RS24285	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HB789_RS24290	COG2965	DNA replication, synthesis of RNA primer
HB789_RS24350	COG1073	alpha beta
HB789_RS24355	COG3650	response to hydrogen peroxide
HB789_RS24365	COG1960	acyl-CoA dehydrogenase activity
HB789_RS24370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB789_RS24375	COG0557	exoribonuclease II activity
HB789_RS24390	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HB789_RS24400	COG0330	HflC and HflK could
HB789_RS24405	COG0330	HflC and HflK could
HB789_RS24410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HB789_RS24430	COG0860	N-Acetylmuramoyl-L-alanine amidase
HB789_RS24435	COG0802	atpase or kinase
HB789_RS24440	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HB789_RS24440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HB789_RS24445	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HB789_RS24465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB789_RS24485	COG1511	domain protein
HB789_RS24485	COG3264	Mechanosensitive ion channel
HB789_RS24500	COG1053	succinate dehydrogenase
HB789_RS24505	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HB789_RS24525	COG2076	Multidrug Resistance protein
HB789_RS24530	COG5510	response to toxic substance
HB789_RS24545	COG1509	lysine 2,3-aminomutase activity
HB789_RS24615	COG0531	amino acid
HB789_RS24620	COG3030	protein affecting phage T7 exclusion by the F plasmid
HB789_RS24625	COG1027	Aspartate ammonia-lyase
HB789_RS24630	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HB789_RS24645	COG1309	transcriptional regulator
HB789_RS24675	COG0457	Tetratricopeptide repeat
HB789_RS24680	COG1649	PFAM Uncharacterised BCR, COG1649
HB789_RS24680	COG0726	polysaccharide deacetylase
HB789_RS24685	COG1215	transferase activity, transferring glycosyl groups
HB789_RS24700	COG0861	Integral membrane protein TerC family
HB789_RS24745	COG1486	melibiose metabolic process
HB789_RS24750	COG2169	Transcriptional regulator
HB789_RS24760	COG2824	Alkylphosphonate utilization operon protein PhnA
HB789_RS24765	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HB789_RS24770	COG2188	Transcriptional regulator
HB789_RS24775	COG3624	Phosphonate C-P lyase system protein PhnG
HB789_RS24780	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HB789_RS24785	COG3626	phosphonate metabolism
HB789_RS24790	COG3627	carbon phosphorus lyase activity
HB789_RS24795	COG4107	phosphonate C-P lyase system protein PhnK
HB789_RS24800	COG4778	phosphonate C-P lyase system protein PhnL
HB789_RS24805	COG3454	Phosphonate metabolism
HB789_RS24815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HB789_RS24825	COG0784	Response regulator, receiver
HB789_RS24825	COG4191	Histidine kinase
HB789_RS24830	COG1129	ABC transporter
HB789_RS24835	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS24870	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HB789_RS24875	COG1301	dicarboxylic acid transport
HB789_RS24885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB789_RS24890	COG3162	membrane
HB789_RS24920	COG3539	Fimbrial protein
HB789_RS24925	COG1346	cytolysis
HB789_RS24930	COG1380	Effector of murein hydrolase LrgA
HB789_RS24935	COG0583	DNA-binding transcription factor activity
HB789_RS24940	COG0025	NhaP-type Na H and K H
HB789_RS24945	COG2252	PERMEase
HB789_RS24950	COG0625	glutathione transferase activity
HB789_RS24955	COG0789	Transcriptional regulator
HB789_RS24965	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HB789_RS24995	COG1234	tRNA 3'-trailer cleavage
HB789_RS25000	COG1609	Transcriptional regulator
HB789_RS25005	COG0483	inositol monophosphate 1-phosphatase activity
HB789_RS25015	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB789_RS25035	COG4771	TonB-dependent receptor
HB789_RS25040	COG0741	lytic transglycosylase activity
HB789_RS25055	COG2315	Protein conserved in bacteria
HB789_RS25060	COG0432	Pfam Uncharacterised protein family UPF0047
HB789_RS25075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HB789_RS25080	COG0305	Participates in initiation and elongation during chromosome replication
HB789_RS25095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB789_RS25105	COG0735	belongs to the Fur family
HB789_RS25110	COG3237	CsbD-like
HB789_RS25120	COG0534	Mate efflux family protein
HB789_RS25130	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HB789_RS25200	COG0251	oxidation-reduction process
HB789_RS25210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HB789_RS25220	COG0527	aspartate kinase activity
HB789_RS25275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HB789_RS25305	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HB789_RS25315	COG0456	acetyltransferase
HB789_RS25345	COG0151	Belongs to the GarS family
HB789_RS25355	COG4191	Histidine kinase
HB789_RS25360	COG3678	ATP-independent chaperone mediated protein folding
HB789_RS25395	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HB789_RS25410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB789_RS25415	COG2104	thiamine diphosphate biosynthetic process
HB789_RS25430	COG3706	GGDEF domain
HB789_RS25440	COG1447	Phosphotransferase system cellobiose-specific component IIA
HB789_RS25445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HB789_RS25480	COG0250	Participates in transcription elongation, termination and antitermination
HB789_RS25525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HB789_RS25555	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HB789_RS25565	COG1739	Uncharacterized protein family UPF0029
HB789_RS25605	COG0805	protein transport
HB789_RS25625	COG3165	ubiquinone biosynthetic process from chorismate
HB789_RS25655	COG0583	DNA-binding transcription factor activity
HB789_RS25660	COG0697	spore germination
HB789_RS25665	COG0561	phosphatase activity
HB789_RS25670	COG2267	carboxylic ester hydrolase activity
HB789_RS25675	COG1280	lysine exporter protein (LysE YggA)
HB789_RS25685	COG1280	lysine exporter protein (LysE YggA)
HB789_RS25715	COG0210	DNA helicase
HB789_RS25720	COG1011	Hydrolase
HB789_RS25750	COG3072	Adenylate cyclase
HB789_RS25765	COG2959	enzyme of heme biosynthesis
HB789_RS25770	COG3071	HemY protein
HB789_RS25815	COG2244	polysaccharide biosynthetic process
HB789_RS25820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HB789_RS25825	COG0456	acetyltransferase
HB789_RS25830	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HB789_RS25835	COG1088	dTDP-glucose 4,6-dehydratase activity
HB789_RS25840	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HB789_RS25845	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HB789_RS25855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HB789_RS25860	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HB789_RS25865	COG3118	belongs to the thioredoxin family
HB789_RS25890	COG1811	Na channel or pump
HB789_RS25900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB789_RS25905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB789_RS25915	COG0583	DNA-binding transcription factor activity
HB789_RS25920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HB789_RS25935	COG3978	acetolactate synthase activity
HB789_RS25955	COG3085	chromosome segregation
HB789_RS26030	COG0583	DNA-binding transcription factor activity
HB789_RS26045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HB789_RS26060	COG3443	Belongs to the bacterial solute-binding protein 9 family
HB789_RS26065	COG2207	Transcriptional regulator
HB789_RS26075	COG0371	Dehydrogenase
HB789_RS26080	COG0697	spore germination
HB789_RS26090	COG0583	DNA-binding transcription factor activity
HB789_RS26100	COG0737	Belongs to the 5'-nucleotidase family
HB789_RS26110	COG0527	aspartate kinase activity
HB789_RS26110	COG0460	homoserine dehydrogenase
HB789_RS26115	COG0626	cystathionine gamma-synthase activity
HB789_RS26130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HB789_RS26135	COG1609	Transcriptional regulator
HB789_RS26140	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB789_RS26155	COG1575	Belongs to the MenA family. Type 1 subfamily
HB789_RS26175	COG3678	ATP-independent chaperone mediated protein folding
HB789_RS26180	COG0745	RESPONSE REGULATOR receiver
HB789_RS26185	COG2205	protein histidine kinase activity
HB789_RS26190	COG2258	MOSC domain
HB789_RS26195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HB789_RS26235	COG1129	ABC transporter
HB789_RS26240	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS26245	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS26250	COG1454	alcohol dehydrogenase
HB789_RS26260	COG2211	Major facilitator Superfamily
HB789_RS26320	COG0205	6-phosphofructokinase activity
HB789_RS26340	COG0437	4 iron, 4 sulfur cluster binding
HB789_RS26345	COG2864	formate dehydrogenase
HB789_RS26360	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HB789_RS26365	COG0657	acetylesterase activity
HB789_RS26370	COG0456	acetyltransferase
HB789_RS26385	COG1011	Hydrolase
HB789_RS26400	COG3852	Histidine kinase
HB789_RS26415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HB789_RS26435	COG0204	Acyl-transferase
HB789_RS26445	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HB789_RS26450	COG3084	Protein conserved in bacteria
HB789_RS26460	COG1763	Mo-molybdopterin cofactor biosynthetic process
HB789_RS26485	COG2186	Transcriptional regulator
HB789_RS26490	COG0477	Major facilitator Superfamily
HB789_RS26495	COG1609	Transcriptional regulator
HB789_RS26500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB789_RS26510	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB789_RS26515	COG1129	ABC transporter
HB789_RS26545	COG1522	sequence-specific DNA binding
HB789_RS26550	COG0716	FMN binding
HB789_RS26565	COG3312	ion transport
HB789_RS26615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HB789_RS26620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HB789_RS26625	COG0573	inorganic phosphate transmembrane transporter activity
HB789_RS26630	COG0581	inorganic phosphate transmembrane transporter activity
HB789_RS26635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HB789_RS26640	COG0704	Plays a role in the regulation of phosphate uptake
HB789_RS26650	COG2382	esterase
HB789_RS26655	COG0363	glucosamine-6-phosphate deaminase activity
HB789_RS26660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB789_RS26665	COG2252	PERMEase
HB789_RS26670	COG0431	NADPH-dependent FMN reductase
HB789_RS26675	COG2091	lysine biosynthetic process via aminoadipic acid
HB789_RS26705	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HB789_RS26730	COG2199	diguanylate cyclase activity
HB789_RS26730	COG2203	Gaf domain
HB789_RS26735	COG5001	Diguanylate cyclase
HB789_RS26735	COG1716	ATPase activity
HB789_RS26750	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HB789_RS26760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB789_RS26805	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB789_RS26835	COG0739	heme binding
HB789_RS26860	COG2084	Dehydrogenase
HB789_RS26865	COG3395	kinase activity
HB789_RS26870	COG0235	Class ii aldolase
HB789_RS26910	COG4172	Belongs to the ABC transporter superfamily
HB789_RS26925	COG0601	transmembrane transport
HB789_RS26930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB789_RS26955	COG1595	DNA-templated transcription, initiation
HB789_RS26960	COG3712	iron ion homeostasis
HB789_RS26965	COG4772	TonB-dependent receptor
HB789_RS26970	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HB789_RS26975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB789_RS26980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB789_RS26985	COG1120	ATPase activity
HB789_RS26990	COG3436	PFAM IS66 Orf2 family protein
HB789_RS27035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HB789_RS27040	COG3118	belongs to the thioredoxin family
HB789_RS27045	COG1902	pentaerythritol trinitrate reductase activity
HB789_RS27050	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HB789_RS27055	COG1028	Short-chain dehydrogenase reductase Sdr
HB789_RS27060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HB789_RS27095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HB789_RS27140	COG4680	protein conserved in bacteria
HB789_RS27150	COG1556	Lactate utilization protein
HB789_RS27155	COG1139	Iron-sulfur cluster binding protein
HB789_RS27160	COG0247	lactate metabolic process
HB789_RS27165	COG0277	FAD linked oxidase domain protein
HB789_RS27170	COG1620	l-lactate permease
HB789_RS27215	COG2205	protein histidine kinase activity
HB789_RS27220	COG0745	RESPONSE REGULATOR receiver
HB789_RS27225	COG1276	copper resistance
HB789_RS27230	COG2372	response to copper ion
HB789_RS27235	COG3667	copper resistance
HB789_RS27260	COG1660	Displays ATPase and GTPase activities
HB789_RS27285	COG0768	penicillin binding
HB789_RS27330	COG3173	Aminoglycoside phosphotransferase
HB789_RS27390	COG0697	spore germination
HB789_RS27475	COG2003	Belongs to the UPF0758 family
HB789_RS27530	COG1609	Transcriptional regulator
HB789_RS27540	COG2223	nitrite transmembrane transporter activity
HB789_RS27595	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HB789_RS27605	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HB789_RS27650	COG3621	Patatin-like phospholipase
HB789_RS27695	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HB789_RS27945	COG3344	reverse transcriptase
HB789_RS28065	COG3941	tape measure
HB789_RS28155	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HB789_RS28160	COG1475	DNA binding
HB789_RS28165	COG1475	DNA binding
HB789_RS28285	COG0328	RNA-DNA hybrid ribonuclease activity
HB789_RS28305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HB789_RS28330	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HB789_RS28340	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB789_RS28345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB789_RS28515	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB789_RS28530	COG1702	phosphate starvation-inducible protein PhoH
HB789_RS28795	COG5001	Diguanylate cyclase
HB789_RS28795	COG3300	MHYT domain
HB789_RS28835	COG3344	reverse transcriptase
HB789_RS28915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HB789_RS29150	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HB789_RS29210	COG3064	Membrane