locus-tag	class	description
CTM43_RS00005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTM43_RS00005	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTM43_RS00015	COG0204	Acyl-transferase
CTM43_RS00025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CTM43_RS00030	COG3084	Protein conserved in bacteria
CTM43_RS00040	COG1763	Mo-molybdopterin cofactor biosynthetic process
CTM43_RS00065	COG2186	Transcriptional regulator
CTM43_RS00070	COG0477	Major facilitator Superfamily
CTM43_RS00075	COG1609	Transcriptional regulator
CTM43_RS00080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTM43_RS00090	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS00095	COG1129	ABC transporter
CTM43_RS00125	COG1522	sequence-specific DNA binding
CTM43_RS00130	COG0716	FMN binding
CTM43_RS00145	COG3312	ion transport
CTM43_RS00200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTM43_RS00205	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CTM43_RS00210	COG0573	inorganic phosphate transmembrane transporter activity
CTM43_RS00215	COG0581	inorganic phosphate transmembrane transporter activity
CTM43_RS00220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTM43_RS00225	COG0704	Plays a role in the regulation of phosphate uptake
CTM43_RS00240	COG2382	esterase
CTM43_RS00245	COG0363	glucosamine-6-phosphate deaminase activity
CTM43_RS00250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTM43_RS00260	COG2252	PERMEase
CTM43_RS00265	COG0431	NADPH-dependent FMN reductase
CTM43_RS00270	COG2091	lysine biosynthetic process via aminoadipic acid
CTM43_RS00300	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CTM43_RS00330	COG0187	DNA topoisomerase II activity
CTM43_RS00335	COG0561	phosphatase activity
CTM43_RS00350	COG2186	Transcriptional regulator
CTM43_RS00355	COG3734	2-keto-3-deoxy-galactonokinase
CTM43_RS00360	COG0800	Aldolase
CTM43_RS00370	COG2271	Major facilitator Superfamily
CTM43_RS00375	COG0823	Involved in the tonB-independent uptake of proteins
CTM43_RS00380	COG5645	(Lipo)protein
CTM43_RS00405	COG2188	Transcriptional regulator
CTM43_RS00420	COG2149	membrane
CTM43_RS00440	COG2610	gluconate transmembrane transporter activity
CTM43_RS00445	COG0583	DNA-binding transcription factor activity
CTM43_RS00450	COG2814	Major facilitator Superfamily
CTM43_RS00475	COG0028	Belongs to the TPP enzyme family
CTM43_RS00480	COG0440	acetolactate synthase activity
CTM43_RS00485	COG2197	response regulator
CTM43_RS00495	COG2271	Major facilitator Superfamily
CTM43_RS00540	COG2188	Transcriptional regulator
CTM43_RS00575	COG4580	involved in the transport of maltose and maltodextrins
CTM43_RS00580	COG1447	Phosphotransferase system cellobiose-specific component IIA
CTM43_RS00585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTM43_RS00585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTM43_RS00595	COG1609	Transcriptional regulator
CTM43_RS00605	COG3384	dioxygenase
CTM43_RS00610	COG0583	DNA-binding transcription factor activity
CTM43_RS00615	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CTM43_RS00620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTM43_RS00625	COG2828	Protein conserved in bacteria
CTM43_RS00640	COG0697	spore germination
CTM43_RS00645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTM43_RS00645	COG1263	PTS System
CTM43_RS00655	COG2814	Major facilitator Superfamily
CTM43_RS00665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTM43_RS00700	COG0583	DNA-binding transcription factor activity
CTM43_RS00725	COG1464	Belongs to the NlpA lipoprotein family
CTM43_RS00740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CTM43_RS00750	COG1064	alcohol dehydrogenase
CTM43_RS00785	COG2211	Major facilitator Superfamily
CTM43_RS00790	COG1501	Belongs to the glycosyl hydrolase 31 family
CTM43_RS00800	COG1486	melibiose metabolic process
CTM43_RS00805	COG1263	PTS System
CTM43_RS00805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTM43_RS00810	COG2982	Protein involved in outer membrane biogenesis
CTM43_RS00815	COG2233	PERMEase
CTM43_RS00820	COG0786	glutamate:sodium symporter activity
CTM43_RS00840	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTM43_RS00865	COG3152	Membrane
CTM43_RS00875	COG1494	fructose-1,6-bisphosphatase
CTM43_RS00880	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTM43_RS00885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTM43_RS00890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTM43_RS00910	COG2860	membrane
CTM43_RS00920	COG2169	Transcriptional regulator
CTM43_RS00920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTM43_RS00925	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CTM43_RS00930	COG1561	YicC-like family, N-terminal region
CTM43_RS00950	COG1131	(ABC) transporter
CTM43_RS00955	COG0842	Transport permease protein
CTM43_RS00985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTM43_RS01020	COG1519	Transferase
CTM43_RS01025	COG1216	Glycosyl transferase, family 2
CTM43_RS01030	COG0438	transferase activity, transferring glycosyl groups
CTM43_RS01040	COG0859	PFAM glycosyl transferase family 9
CTM43_RS01050	COG1216	Glycosyl transferase, family 2
CTM43_RS01050	COG1442	glycosyl transferase family 8
CTM43_RS01055	COG3307	-O-antigen
CTM43_RS01060	COG0438	transferase activity, transferring glycosyl groups
CTM43_RS01065	COG0859	PFAM glycosyl transferase family 9
CTM43_RS01080	COG0156	8-amino-7-oxononanoate synthase activity
CTM43_RS01090	COG0463	Glycosyl transferase, family 2
CTM43_RS01095	COG2861	carbohydrate metabolic process
CTM43_RS01100	COG4942	peptidase
CTM43_RS01110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CTM43_RS01115	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTM43_RS01140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CTM43_RS01150	COG2186	Transcriptional regulator
CTM43_RS01170	COG3722	fumarate hydratase activity
CTM43_RS01195	COG0625	glutathione transferase activity
CTM43_RS01205	COG3276	selenocysteine insertion sequence binding
CTM43_RS01210	COG1414	Transcriptional regulator
CTM43_RS01215	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTM43_RS01220	COG3977	Valine--pyruvate aminotransferase
CTM43_RS01225	COG0366	Alpha amylase catalytic
CTM43_RS01230	COG2992	FlgJ-related protein
CTM43_RS01235	COG2207	Transcriptional regulator
CTM43_RS01235	COG1609	Transcriptional regulator
CTM43_RS01240	COG4214	carbohydrate transport
CTM43_RS01250	COG4213	ABC transporter substrate-binding protein
CTM43_RS01270	COG4682	membrane
CTM43_RS01275	COG4682	membrane
CTM43_RS01280	COG3274	enterobacterial common antigen metabolic process
CTM43_RS01340	COG1278	Cold shock
CTM43_RS01345	COG2944	sequence-specific DNA binding
CTM43_RS01350	COG2814	Major facilitator Superfamily
CTM43_RS01375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTM43_RS01385	COG1609	Transcriptional regulator
CTM43_RS01390	COG2885	chlorophyll binding
CTM43_RS01395	COG0243	molybdopterin cofactor binding
CTM43_RS01400	COG0456	acetyltransferase
CTM43_RS01405	COG2818	Glycosylase
CTM43_RS01410	COG5571	outer membrane autotransporter
CTM43_RS01415	COG2223	nitrite transmembrane transporter activity
CTM43_RS01445	COG0747	negative chemotaxis
CTM43_RS01450	COG0601	transmembrane transport
CTM43_RS01455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTM43_RS01460	COG0444	Belongs to the ABC transporter superfamily
CTM43_RS01465	COG4608	Belongs to the ABC transporter superfamily
CTM43_RS01480	COG2894	cell division
CTM43_RS01490	COG1215	transferase activity, transferring glycosyl groups
CTM43_RS01495	COG0457	Tetratricopeptide repeat
CTM43_RS01510	COG2194	sulfuric ester hydrolase activity
CTM43_RS01540	COG1215	transferase activity, transferring glycosyl groups
CTM43_RS01545	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CTM43_RS01550	COG0457	Tetratricopeptide repeat
CTM43_RS01550	COG3118	belongs to the thioredoxin family
CTM43_RS01555	COG2199	diguanylate cyclase activity
CTM43_RS01555	COG2200	EAL domain
CTM43_RS01565	COG0612	Peptidase, M16
CTM43_RS01580	COG2982	Protein involved in outer membrane biogenesis
CTM43_RS01585	COG0477	Major facilitator Superfamily
CTM43_RS01590	COG1295	ribonuclease BN
CTM43_RS01595	COG0583	DNA-binding transcription factor activity
CTM43_RS01600	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS01605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTM43_RS01615	COG1454	alcohol dehydrogenase
CTM43_RS01625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTM43_RS01630	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CTM43_RS01635	COG0671	phosphoesterase, PA-phosphatase related
CTM43_RS01655	COG0589	response to stress
CTM43_RS01665	COG0306	phosphate transporter
CTM43_RS01670	COG2081	HI0933 family
CTM43_RS01675	COG2239	Acts as a magnesium transporter
CTM43_RS01690	COG1124	(ABC) transporter
CTM43_RS01700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTM43_RS01705	COG0601	transmembrane transport
CTM43_RS01710	COG0747	negative chemotaxis
CTM43_RS01725	COG3479	Phenolic acid decarboxylase
CTM43_RS01765	COG0628	permease
CTM43_RS01770	COG0477	Major facilitator Superfamily
CTM43_RS01780	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CTM43_RS01800	COG3714	YhhN family
CTM43_RS01810	COG3776	membrane
CTM43_RS01815	COG0742	ribosomal rna small subunit methyltransferase
CTM43_RS01820	COG0552	protein localization to endoplasmic reticulum
CTM43_RS01825	COG2884	Cell division ATP-binding protein ftsE
CTM43_RS01830	COG2177	Part of the ABC transporter FtsEX involved in
CTM43_RS01845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTM43_RS01855	COG0683	leucine binding
CTM43_RS01870	COG0683	leucine binding
CTM43_RS01875	COG0559	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS01925	COG0584	glycerophosphoryl diester phosphodiesterase
CTM43_RS01940	COG1247	-acetyltransferase
CTM43_RS01950	COG0673	inositol 2-dehydrogenase activity
CTM43_RS01955	COG1741	Belongs to the pirin family
CTM43_RS01960	COG1609	Transcriptional regulator
CTM43_RS01965	COG3265	gluconokinase activity
CTM43_RS01970	COG2610	gluconate transmembrane transporter activity
CTM43_RS01980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CTM43_RS02005	COG0058	SHG alpha-glucan phosphorylase activity
CTM43_RS02020	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CTM43_RS02035	COG1349	DNA-binding transcription factor activity
CTM43_RS02050	COG0058	SHG alpha-glucan phosphorylase activity
CTM43_RS02055	COG1640	4-alpha-glucanotransferase
CTM43_RS02060	COG2610	gluconate transmembrane transporter activity
CTM43_RS02070	COG1040	competence protein
CTM43_RS02095	COG1918	ferrous iron import across plasma membrane
CTM43_RS02100	COG2183	response to ionizing radiation
CTM43_RS02105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTM43_RS02130	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTM43_RS02135	COG1011	Hydrolase
CTM43_RS02145	COG0494	nUDIX hydrolase
CTM43_RS02150	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CTM43_RS02175	COG4796	Type ii and iii secretion system protein
CTM43_RS02195	COG3266	domain, Protein
CTM43_RS02200	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CTM43_RS02205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTM43_RS02230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTM43_RS02235	COG0402	S-adenosylhomocysteine deaminase activity
CTM43_RS02240	COG0738	Major facilitator superfamily
CTM43_RS02265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTM43_RS02270	COG1289	transmembrane transporter activity
CTM43_RS02280	COG1765	OsmC-like protein
CTM43_RS02285	COG3954	Phosphoribulokinase
CTM43_RS02295	COG0429	hydrolase of the alpha beta-hydrolase fold
CTM43_RS02305	COG0488	(ABC) transporter
CTM43_RS02320	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CTM43_RS02325	COG1047	Peptidyl-prolyl cis-trans
CTM43_RS02335	COG0545	Peptidyl-prolyl cis-trans isomerase
CTM43_RS02340	COG2964	Protein conserved in bacteria
CTM43_RS02395	COG0051	transcription antitermination factor activity, RNA binding
CTM43_RS02420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CTM43_RS02435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CTM43_RS02500	COG0201	protein transport
CTM43_RS02525	COG0202	RNA polymerase activity
CTM43_RS02540	COG0789	Transcriptional regulator
CTM43_RS02545	COG3036	rescue of stalled ribosome
CTM43_RS02575	COG0758	DNA mediated transformation
CTM43_RS02585	COG0551	DNA topoisomerase type I activity
CTM43_RS02605	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTM43_RS02640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTM43_RS02645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTM43_RS02650	COG1309	transcriptional regulator
CTM43_RS02675	COG4145	pantothenate transmembrane transporter activity
CTM43_RS02680	COG3924	membrane
CTM43_RS02685	COG0439	Biotin carboxylase
CTM43_RS02690	COG0511	ligase activity, forming carbon-carbon bonds
CTM43_RS02715	COG2200	EAL domain
CTM43_RS02715	COG2199	diguanylate cyclase activity
CTM43_RS02720	COG1077	Cell shape determining protein MreB Mrl
CTM43_RS02725	COG1792	Involved in formation and maintenance of cell shape
CTM43_RS02730	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CTM43_RS02740	COG1530	ribonuclease E activity
CTM43_RS02745	COG3164	Protein of unknown function
CTM43_RS02750	COG0312	modulator of DNA gyrase
CTM43_RS02755	COG0583	DNA-binding transcription factor activity
CTM43_RS02770	COG1289	transmembrane transporter activity
CTM43_RS02775	COG2732	(Barnase) inhibitor
CTM43_RS02800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTM43_RS02805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTM43_RS02810	COG3105	Protein conserved in bacteria
CTM43_RS02815	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CTM43_RS02835	COG0625	glutathione transferase activity
CTM43_RS02840	COG2969	positive regulation of protein catabolic process
CTM43_RS02850	COG0493	'glutamate synthase
CTM43_RS02855	COG0070	glutamate synthase
CTM43_RS02855	COG0069	glutamate synthase activity
CTM43_RS02855	COG0067	glutamate synthase
CTM43_RS02860	COG1242	4 iron, 4 sulfur cluster binding
CTM43_RS02865	COG2271	Major facilitator Superfamily
CTM43_RS02870	COG1063	alcohol dehydrogenase
CTM43_RS02875	COG1312	Catalyzes the dehydration of D-mannonate
CTM43_RS02880	COG5002	protein histidine kinase activity
CTM43_RS02880	COG2198	Histidine kinase
CTM43_RS02880	COG0784	Response regulator, receiver
CTM43_RS02885	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CTM43_RS02890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTM43_RS02895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTM43_RS02905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTM43_RS02910	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CTM43_RS02915	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CTM43_RS02920	COG1137	ATPase activity
CTM43_RS02925	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CTM43_RS02930	COG3117	lipopolysaccharide transmembrane transporter activity
CTM43_RS02935	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CTM43_RS02945	COG0530	calcium, potassium:sodium antiporter activity
CTM43_RS02955	COG1127	ABC transporter
CTM43_RS02960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CTM43_RS02965	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CTM43_RS02970	COG2854	intermembrane phospholipid transfer
CTM43_RS02975	COG3113	response to antibiotic
CTM43_RS02980	COG5007	Belongs to the BolA IbaG family
CTM43_RS02990	COG3423	Transcriptional regulator
CTM43_RS02995	COG0142	geranyltranstransferase activity
CTM43_RS03010	COG0697	spore germination
CTM43_RS03020	COG2027	D-alanyl-D-alanine carboxypeptidase
CTM43_RS03030	COG1534	Rna-binding protein
CTM43_RS03040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTM43_RS03045	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CTM43_RS03055	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CTM43_RS03095	COG0195	Participates in both transcription termination and antitermination
CTM43_RS03145	COG0814	amino acid
CTM43_RS03150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTM43_RS03155	COG0826	peptidase U32
CTM43_RS03160	COG0826	peptidase U32
CTM43_RS03165	COG3154	lipid carrier protein
CTM43_RS03170	COG3153	acetyltransferase
CTM43_RS03185	COG0693	protein deglycase activity
CTM43_RS03190	COG0702	epimerase
CTM43_RS03195	COG0701	Predicted permease
CTM43_RS03200	COG2823	Periplasmic or secreted lipoprotein
CTM43_RS03220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CTM43_RS03225	COG2721	sulfolactate sulfo-lyase activity
CTM43_RS03235	COG2271	Major facilitator Superfamily
CTM43_RS03245	COG2084	Dehydrogenase
CTM43_RS03250	COG1929	Belongs to the glycerate kinase type-1 family
CTM43_RS03275	COG1741	Belongs to the pirin family
CTM43_RS03280	COG0583	DNA-binding transcription factor activity
CTM43_RS03285	COG3152	Membrane
CTM43_RS03290	COG0435	Glutathione S-transferase
CTM43_RS03295	COG2259	Doxx family
CTM43_RS03305	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CTM43_RS03310	COG4575	ribosome binding
CTM43_RS03315	COG1422	Protein of unknown function (DUF1090)
CTM43_RS03325	COG0586	Pfam SNARE associated Golgi protein
CTM43_RS03330	COG2186	Transcriptional regulator
CTM43_RS03335	COG2271	Major facilitator Superfamily
CTM43_RS03345	COG2721	sulfolactate sulfo-lyase activity
CTM43_RS03360	COG0861	Integral membrane protein TerC family
CTM43_RS03365	COG0673	inositol 2-dehydrogenase activity
CTM43_RS03370	COG1451	nucleotide metabolic process
CTM43_RS03390	COG1902	pentaerythritol trinitrate reductase activity
CTM43_RS03390	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTM43_RS03435	COG3408	Glycogen debranching enzyme
CTM43_RS03435	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CTM43_RS03445	COG0531	amino acid
CTM43_RS03450	COG0531	amino acid
CTM43_RS03455	COG2731	YhcH YjgK YiaL family protein
CTM43_RS03460	COG3250	beta-galactosidase activity
CTM43_RS03465	COG1609	Transcriptional regulator
CTM43_RS03470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTM43_RS03480	COG1695	Transcriptional regulator
CTM43_RS03485	COG2375	cellular response to nickel ion
CTM43_RS03500	COG1461	Dihydroxyacetone kinase
CTM43_RS03505	COG2376	Dihydroxyacetone kinase
CTM43_RS03580	COG3247	response to pH
CTM43_RS03590	COG2205	protein histidine kinase activity
CTM43_RS03590	COG0784	Response regulator, receiver
CTM43_RS03590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS03590	COG2198	Histidine kinase
CTM43_RS03595	COG2197	response regulator
CTM43_RS03620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CTM43_RS03625	COG0358	DNA primase activity
CTM43_RS03630	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CTM43_RS03690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CTM43_RS03705	COG4991	sh3 domain protein
CTM43_RS03710	COG3025	triphosphatase activity
CTM43_RS03730	COG2960	long-chain fatty acid transporting porin activity
CTM43_RS03745	COG3384	dioxygenase
CTM43_RS03750	COG0754	glutathionylspermidine amidase activity
CTM43_RS03765	COG0494	nUDIX hydrolase
CTM43_RS03770	COG3151	Protein conserved in bacteria
CTM43_RS03775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTM43_RS03780	COG3150	esterase
CTM43_RS03790	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CTM43_RS03795	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTM43_RS03800	COG0642	Histidine kinase
CTM43_RS03810	COG3111	PFAM Bacterial OB fold (BOF) protein
CTM43_RS03815	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CTM43_RS03820	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CTM43_RS03825	COG0204	Acyl-transferase
CTM43_RS03830	COG2132	Multicopper oxidase
CTM43_RS03835	COG1032	radical SAM domain protein
CTM43_RS03845	COG0656	L-ascorbic acid biosynthetic process
CTM43_RS03850	COG1979	alcohol dehydrogenase
CTM43_RS03855	COG2207	Transcriptional regulator
CTM43_RS03860	COG0586	Pfam SNARE associated Golgi protein
CTM43_RS03865	COG0626	cystathionine gamma-synthase activity
CTM43_RS03880	COG0848	biopolymer transport protein
CTM43_RS03900	COG0625	glutathione transferase activity
CTM43_RS03910	COG0754	glutathionylspermidine amidase activity
CTM43_RS03915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTM43_RS03935	COG0583	DNA-binding transcription factor activity
CTM43_RS03940	COG0626	cystathionine gamma-synthase activity
CTM43_RS03955	COG3121	Chaperone
CTM43_RS03970	COG3121	Chaperone
CTM43_RS03975	COG3121	Chaperone
CTM43_RS03980	COG3188	usher protein
CTM43_RS04010	COG1811	Na channel or pump
CTM43_RS04020	COG1982	Orn Lys Arg decarboxylase major
CTM43_RS04025	COG2211	Major facilitator Superfamily
CTM43_RS04040	COG1194	a g-specific adenine glycosylase
CTM43_RS04050	COG3171	Protein conserved in bacteria
CTM43_RS04060	COG4214	carbohydrate transport
CTM43_RS04075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTM43_RS04090	COG0762	integral membrane protein
CTM43_RS04095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CTM43_RS04100	COG2805	Type II/IV secretion system protein
CTM43_RS04120	COG0189	ligase activity
CTM43_RS04125	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTM43_RS04130	COG2356	endonuclease I
CTM43_RS04140	COG2814	Major facilitator Superfamily
CTM43_RS04175	COG0501	Belongs to the peptidase M48B family
CTM43_RS04180	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTM43_RS04195	COG0191	fructose-bisphosphate aldolase activity
CTM43_RS04200	COG0668	transmembrane transport
CTM43_RS04210	COG2968	Membrane
CTM43_RS04225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTM43_RS04230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTM43_RS04250	COG0006	proline dipeptidase activity
CTM43_RS04255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTM43_RS04260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTM43_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS04285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTM43_RS04305	COG2723	6-phospho-beta-galactosidase activity
CTM43_RS04310	COG1737	Transcriptional regulator
CTM43_RS04320	COG1272	protein, Hemolysin III
CTM43_RS04330	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CTM43_RS04340	COG0716	FMN binding
CTM43_RS04345	COG4974	Belongs to the 'phage' integrase family
CTM43_RS04355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTM43_RS04375	COG4942	peptidase
CTM43_RS04465	COG4974	Belongs to the 'phage' integrase family
CTM43_RS04475	COG3646	Phage regulatory protein
CTM43_RS04495	COG2814	Major facilitator Superfamily
CTM43_RS04515	COG2197	response regulator
CTM43_RS04525	COG0784	Response regulator, receiver
CTM43_RS04525	COG2205	protein histidine kinase activity
CTM43_RS04525	COG2198	Histidine kinase
CTM43_RS04525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS04530	COG2197	response regulator
CTM43_RS04565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTM43_RS04570	COG0601	transmembrane transport
CTM43_RS04580	COG4413	Urea transporter
CTM43_RS04590	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CTM43_RS04610	COG0832	Belongs to the urease beta subunit family
CTM43_RS04615	COG0831	urea catabolic process
CTM43_RS04620	COG0004	ammonium transporteR
CTM43_RS04635	COG0477	Major facilitator Superfamily
CTM43_RS04640	COG1566	PFAM secretion protein HlyD family protein
CTM43_RS04645	COG2197	response regulator
CTM43_RS04650	COG2198	Histidine kinase
CTM43_RS04650	COG0784	Response regulator, receiver
CTM43_RS04650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS04650	COG2205	protein histidine kinase activity
CTM43_RS04670	COG2200	EAL domain
CTM43_RS04685	COG0667	Aldo Keto reductase
CTM43_RS04720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CTM43_RS04725	COG1393	Belongs to the ArsC family
CTM43_RS04740	COG1538	Outer membrane efflux protein
CTM43_RS04745	COG1289	transmembrane transporter activity
CTM43_RS04760	COG3592	Divergent 4Fe-4S mono-cluster
CTM43_RS04765	COG2388	GCN5-related N-acetyl-transferase
CTM43_RS04775	COG3539	Fimbrial protein
CTM43_RS04780	COG3539	Fimbrial protein
CTM43_RS04785	COG3539	Fimbrial protein
CTM43_RS04790	COG3188	usher protein
CTM43_RS04795	COG3121	Chaperone
CTM43_RS04800	COG3539	Fimbrial protein
CTM43_RS04810	COG4974	Belongs to the 'phage' integrase family
CTM43_RS04815	COG0582	viral genome integration into host DNA
CTM43_RS04825	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CTM43_RS04830	COG1846	Transcriptional regulator
CTM43_RS04835	COG0697	spore germination
CTM43_RS04885	COG0667	Aldo Keto reductase
CTM43_RS04890	COG0814	amino acid
CTM43_RS04905	COG0183	Belongs to the thiolase family
CTM43_RS04915	COG0823	Involved in the tonB-independent uptake of proteins
CTM43_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS04925	COG2814	Major facilitator Superfamily
CTM43_RS04955	COG3842	ATPase activity
CTM43_RS04960	COG0395	ABC-type sugar transport system, permease component
CTM43_RS04965	COG1175	transmembrane transport
CTM43_RS04970	COG1917	Cupin 2, conserved barrel domain protein
CTM43_RS04975	COG1794	racemase activity, acting on amino acids and derivatives
CTM43_RS04980	COG0583	DNA-binding transcription factor activity
CTM43_RS04990	COG1609	Transcriptional regulator
CTM43_RS04995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTM43_RS05000	COG2723	6-phospho-beta-galactosidase activity
CTM43_RS05005	COG2186	Transcriptional regulator
CTM43_RS05015	COG1609	Transcriptional regulator
CTM43_RS05040	COG0667	Aldo Keto reductase
CTM43_RS05050	COG0861	Integral membrane protein TerC family
CTM43_RS05085	COG2165	general secretion pathway protein
CTM43_RS05090	COG4795	General secretion pathway protein
CTM43_RS05100	COG4967	type IV pilus modification protein PilV
CTM43_RS05105	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CTM43_RS05110	COG1025	Belongs to the peptidase M16 family
CTM43_RS05115	COG1074	ATP-dependent DNA helicase activity
CTM43_RS05120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTM43_RS05130	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CTM43_RS05130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CTM43_RS05135	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTM43_RS05140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CTM43_RS05170	COG4656	Part of a membrane complex involved in electron transport
CTM43_RS05175	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS05175	COG1454	alcohol dehydrogenase
CTM43_RS05205	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CTM43_RS05365	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CTM43_RS05370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTM43_RS05375	COG2166	iron-sulfur cluster assembly
CTM43_RS05380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTM43_RS05390	COG0583	DNA-binding transcription factor activity
CTM43_RS05395	COG2363	Small membrane protein
CTM43_RS05405	COG1349	DNA-binding transcription factor activity
CTM43_RS05425	COG0738	Major facilitator superfamily
CTM43_RS05430	COG0235	Class ii aldolase
CTM43_RS05435	COG1454	alcohol dehydrogenase
CTM43_RS05450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTM43_RS05465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTM43_RS05470	COG2011	ABC-type metal ion transport system permease component
CTM43_RS05475	COG1464	Belongs to the NlpA lipoprotein family
CTM43_RS05485	COG0477	Major facilitator Superfamily
CTM43_RS05495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTM43_RS05500	COG1760	l-serine dehydratase
CTM43_RS05505	COG0814	amino acid
CTM43_RS05510	COG1611	Belongs to the LOG family
CTM43_RS05525	COG3098	single-species biofilm formation
CTM43_RS05530	COG0564	pseudouridine synthase activity
CTM43_RS05535	COG0716	FMN binding
CTM43_RS05540	COG2271	Major facilitator Superfamily
CTM43_RS05545	COG4948	Mandelate Racemase Muconate Lactonizing
CTM43_RS05550	COG4948	Mandelate Racemase Muconate Lactonizing
CTM43_RS05555	COG1929	Belongs to the glycerate kinase type-1 family
CTM43_RS05565	COG4999	Histidine kinase
CTM43_RS05565	COG3850	Histidine kinase
CTM43_RS05565	COG3437	response regulator, receiver
CTM43_RS05565	COG2205	protein histidine kinase activity
CTM43_RS05575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTM43_RS05580	COG3956	TIGRFAM MazG family protein
CTM43_RS05600	COG0602	queuosine metabolic process
CTM43_RS05605	COG0720	synthase
CTM43_RS05625	COG2234	aminopeptidase activity
CTM43_RS05685	COG1388	LysM domain
CTM43_RS05685	COG4942	peptidase
CTM43_RS05690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CTM43_RS05715	COG0163	prenyltransferase activity
CTM43_RS05720	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CTM43_RS05745	COG0582	viral genome integration into host DNA
CTM43_RS05800	COG0464	growth
CTM43_RS05815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTM43_RS05820	COG4558	Periplasmic binding protein
CTM43_RS05825	COG3720	iron ion transport
CTM43_RS05845	COG0679	Auxin Efflux Carrier
CTM43_RS05860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTM43_RS05865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTM43_RS05870	COG1121	(ABC) transporter
CTM43_RS05880	COG1609	Transcriptional regulator
CTM43_RS05885	COG1940	carbohydrate kinase activity
CTM43_RS05890	COG1447	Phosphotransferase system cellobiose-specific component IIA
CTM43_RS05895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTM43_RS05900	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTM43_RS05905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTM43_RS05915	COG4580	involved in the transport of maltose and maltodextrins
CTM43_RS05925	COG2723	6-phospho-beta-galactosidase activity
CTM43_RS05935	COG0309	Hydrogenase expression formation protein (HypE)
CTM43_RS05940	COG0409	Hydrogenase expression formation protein
CTM43_RS05945	COG0298	carbon dioxide binding
CTM43_RS05950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CTM43_RS05970	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTM43_RS05975	COG0651	ATP synthesis coupled electron transport
CTM43_RS05980	COG0650	Formate hydrogenlyase subunit 4
CTM43_RS05985	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CTM43_RS05985	COG3261	NADH dehydrogenase
CTM43_RS05990	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTM43_RS05995	COG3260	NADH ubiquinone oxidoreductase 20
CTM43_RS06005	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CTM43_RS06015	COG2723	6-phospho-beta-galactosidase activity
CTM43_RS06020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTM43_RS06020	COG1263	PTS System
CTM43_RS06025	COG1609	Transcriptional regulator
CTM43_RS06030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTM43_RS06035	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CTM43_RS06040	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CTM43_RS06070	COG1349	DNA-binding transcription factor activity
CTM43_RS06075	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTM43_RS06080	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS06090	COG3732	PTS system glucitol sorbitol-specific
CTM43_RS06095	COG3730	PTS system glucitol sorbitol-specific
CTM43_RS06100	COG2951	lytic endotransglycosylase activity
CTM43_RS06110	COG1121	(ABC) transporter
CTM43_RS06115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTM43_RS06120	COG0803	Belongs to the bacterial solute-binding protein 9 family
CTM43_RS06125	COG1546	Belongs to the CinA family
CTM43_RS06150	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CTM43_RS06180	COG2823	Periplasmic or secreted lipoprotein
CTM43_RS06185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTM43_RS06190	COG1238	metal cluster binding
CTM43_RS06210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTM43_RS06215	COG2814	Major facilitator Superfamily
CTM43_RS06220	COG1566	PFAM secretion protein HlyD family protein
CTM43_RS06225	COG1846	Transcriptional regulator
CTM43_RS06235	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTM43_RS06245	COG4176	ABC-type proline glycine betaine transport system permease component
CTM43_RS06260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTM43_RS06270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTM43_RS06275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTM43_RS06280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTM43_RS06285	COG4575	ribosome binding
CTM43_RS06310	COG2916	Histone family protein nucleoid-structuring protein H-NS
CTM43_RS06325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CTM43_RS06330	COG0640	Transcriptional regulator
CTM43_RS06340	COG0583	DNA-binding transcription factor activity
CTM43_RS06345	COG3284	Transcriptional regulator
CTM43_RS06355	COG3539	Fimbrial protein
CTM43_RS06360	COG3121	Chaperone
CTM43_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS06405	COG0235	Class ii aldolase
CTM43_RS06410	COG1126	abc transporter atp-binding protein
CTM43_RS06415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS06450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTM43_RS06455	COG2207	Transcriptional regulator
CTM43_RS06455	COG3708	Transcriptional regulator
CTM43_RS06485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CTM43_RS06505	COG0582	viral genome integration into host DNA
CTM43_RS06560	COG4581	dead DEAH box helicase
CTM43_RS06590	COG0582	viral genome integration into host DNA
CTM43_RS06605	COG2867	negative regulation of translational initiation
CTM43_RS06620	COG0497	DNA recombination
CTM43_RS06640	COG4536	flavin adenine dinucleotide binding
CTM43_RS06645	COG4137	Cytochrome C assembly protein
CTM43_RS06650	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTM43_RS06685	COG2885	chlorophyll binding
CTM43_RS06690	COG2199	diguanylate cyclase activity
CTM43_RS06700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTM43_RS06705	COG0287	Prephenate dehydrogenase
CTM43_RS06705	COG1605	Chorismate mutase
CTM43_RS06715	COG0077	Prephenate dehydratase
CTM43_RS06715	COG1605	Chorismate mutase
CTM43_RS06725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CTM43_RS06730	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTM43_RS06745	COG0542	response to heat
CTM43_RS06775	COG0477	Major facilitator Superfamily
CTM43_RS06780	COG5544	Lipoprotein
CTM43_RS06785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTM43_RS06795	COG3148	PFAM DTW domain containing protein
CTM43_RS06800	COG3118	belongs to the thioredoxin family
CTM43_RS06805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTM43_RS06820	COG0513	Belongs to the DEAD box helicase family
CTM43_RS06830	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CTM43_RS06845	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CTM43_RS06850	COG3026	antisigma factor binding
CTM43_RS06855	COG3086	response to oxidative stress
CTM43_RS06865	COG0681	Belongs to the peptidase S26 family
CTM43_RS06885	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CTM43_RS06895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTM43_RS06900	COG1737	Transcriptional regulator
CTM43_RS06905	COG0560	Phosphoserine phosphatase
CTM43_RS06920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTM43_RS06920	COG0047	phosphoribosylformylglycinamidine synthase activity
CTM43_RS06930	COG2205	protein histidine kinase activity
CTM43_RS06935	COG3170	Tfp pilus assembly protein FimV
CTM43_RS06940	COG2204	response regulator
CTM43_RS06945	COG0347	Belongs to the P(II) protein family
CTM43_RS06950	COG1017	nitric oxide dioxygenase activity
CTM43_RS06950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTM43_RS06960	COG2259	Doxx family
CTM43_RS06975	COG2814	Major facilitator Superfamily
CTM43_RS06975	COG0477	Major facilitator Superfamily
CTM43_RS06980	COG2017	converts alpha-aldose to the beta-anomer
CTM43_RS06985	COG2814	Major facilitator Superfamily
CTM43_RS06990	COG3711	transcriptional antiterminator
CTM43_RS06995	COG3683	transport system, periplasmic component
CTM43_RS07000	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CTM43_RS07030	COG0822	iron-sulfur transferase activity
CTM43_RS07050	COG0633	Ferredoxin
CTM43_RS07055	COG2975	iron-sulfur cluster assembly
CTM43_RS07075	COG2897	thiosulfate sulfurtransferase activity
CTM43_RS07080	COG2373	Large extracellular alpha-helical protein
CTM43_RS07085	COG4953	penicillin-binding protein 1C
CTM43_RS07120	COG2976	Protein conserved in bacteria
CTM43_RS07140	COG1645	bacterial-type flagellum-dependent swarming motility
CTM43_RS07150	COG0516	GMP reductase activity
CTM43_RS07150	COG0517	IMP dehydrogenase activity
CTM43_RS07160	COG3119	arylsulfatase activity
CTM43_RS07165	COG0641	radical SAM
CTM43_RS07185	COG2200	EAL domain
CTM43_RS07200	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CTM43_RS07215	COG2723	6-phospho-beta-galactosidase activity
CTM43_RS07225	COG2233	PERMEase
CTM43_RS07240	COG1393	Belongs to the ArsC family
CTM43_RS07245	COG4783	chaperone-mediated protein folding
CTM43_RS07250	COG0628	permease
CTM43_RS07255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CTM43_RS07260	COG2716	regulation of RNA biosynthetic process
CTM43_RS07270	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CTM43_RS07280	COG2321	neutral zinc metallopeptidase
CTM43_RS07285	COG1444	tRNA N-acetyltransferase activity
CTM43_RS07290	COG0400	carboxylic ester hydrolase activity
CTM43_RS07305	COG1393	Belongs to the ArsC family
CTM43_RS07315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTM43_RS07325	COG0493	'glutamate synthase
CTM43_RS07325	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTM43_RS07335	COG5342	invasion associated locus B
CTM43_RS07340	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTM43_RS07345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTM43_RS07355	COG4810	utilization protein
CTM43_RS07445	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTM43_RS07465	COG2837	iron assimilation
CTM43_RS07475	COG4150	thiosulfate binding
CTM43_RS07480	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CTM43_RS07485	COG4208	sulfate ABC transporter
CTM43_RS07490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CTM43_RS07500	COG4319	ketosteroid isomerase
CTM43_RS07535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTM43_RS07555	COG3530	Putative quorum-sensing-regulated virulence factor
CTM43_RS07560	COG0385	Bile acid
CTM43_RS07565	COG0583	DNA-binding transcription factor activity
CTM43_RS07600	COG3415	Transposase
CTM43_RS07605	COG3415	Transposase
CTM43_RS07620	COG2199	diguanylate cyclase activity
CTM43_RS07620	COG2200	EAL domain
CTM43_RS07625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CTM43_RS07640	COG0667	Aldo Keto reductase
CTM43_RS07645	COG3961	Belongs to the TPP enzyme family
CTM43_RS07660	COG3279	Response regulator of the LytR AlgR family
CTM43_RS07665	COG3275	phosphorelay sensor kinase activity
CTM43_RS07675	COG0436	Aminotransferase
CTM43_RS07685	COG2807	transmembrane transport
CTM43_RS07690	COG0590	tRNA wobble adenosine to inosine editing
CTM43_RS07695	COG0583	DNA-binding transcription factor activity
CTM43_RS07815	COG4974	Belongs to the 'phage' integrase family
CTM43_RS07910	COG3429	Glucose-6-phosphate dehydrogenase subunit
CTM43_RS07910	COG3409	Peptidoglycan-binding domain 1 protein
CTM43_RS07930	COG1475	DNA binding
CTM43_RS07960	COG3422	double-strand break repair
CTM43_RS07975	COG0582	viral genome integration into host DNA
CTM43_RS07990	COG2853	Lipoprotein
CTM43_RS08000	COG3691	Protein conserved in bacteria
CTM43_RS08015	COG2062	phosphohistidine phosphatase, SixA
CTM43_RS08040	COG0730	response to heat
CTM43_RS08045	COG3101	peptidyl-lysine hydroxylation
CTM43_RS08060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTM43_RS08080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CTM43_RS08090	COG0586	Pfam SNARE associated Golgi protein
CTM43_RS08100	COG0285	dihydrofolate synthase activity
CTM43_RS08105	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CTM43_RS08110	COG1286	toxin biosynthetic process
CTM43_RS08115	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CTM43_RS08120	COG0163	prenyltransferase activity
CTM43_RS08140	COG4160	amino acid transport
CTM43_RS08145	COG4598	ABC transporter
CTM43_RS08155	COG1090	epimerase
CTM43_RS08160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CTM43_RS08165	COG0625	glutathione transferase activity
CTM43_RS08170	COG0625	glutathione transferase activity
CTM43_RS08175	COG0622	Phosphoesterase
CTM43_RS08180	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CTM43_RS08185	COG0280	phosphate acetyltransferase
CTM43_RS08185	COG0857	belongs to the CobB CobQ family
CTM43_RS08205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTM43_RS08210	COG0490	domain, Protein
CTM43_RS08210	COG0471	metal ion transport
CTM43_RS08220	COG0436	Aminotransferase
CTM43_RS08225	COG0583	DNA-binding transcription factor activity
CTM43_RS08275	COG0839	Belongs to the complex I subunit 6 family
CTM43_RS08285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTM43_RS08290	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTM43_RS08305	COG2153	protein acetylation
CTM43_RS08310	COG1169	isochorismate synthase
CTM43_RS08335	COG0318	PFAM AMP-dependent synthetase and ligase
CTM43_RS08345	COG5464	transposase or invertase
CTM43_RS08365	COG1414	Transcriptional regulator
CTM43_RS08375	COG2271	Major facilitator Superfamily
CTM43_RS08385	COG0247	lactate metabolic process
CTM43_RS08395	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CTM43_RS08400	COG2271	Major facilitator Superfamily
CTM43_RS08405	COG0584	glycerophosphoryl diester phosphodiesterase
CTM43_RS08415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTM43_RS08445	COG0183	Belongs to the thiolase family
CTM43_RS08450	COG2031	fatty acid transporter
CTM43_RS08455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTM43_RS08460	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTM43_RS08465	COG2204	response regulator
CTM43_RS08470	COG3852	Histidine kinase
CTM43_RS08475	COG0784	Response regulator, receiver
CTM43_RS08475	COG2205	protein histidine kinase activity
CTM43_RS08485	COG0642	Histidine kinase
CTM43_RS08485	COG2198	Histidine kinase
CTM43_RS08500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTM43_RS08500	COG2169	Transcriptional regulator
CTM43_RS08505	COG3145	DNA-N1-methyladenine dioxygenase activity
CTM43_RS08510	COG4615	Cyclic peptide transporter
CTM43_RS08515	COG2239	Acts as a magnesium transporter
CTM43_RS08520	COG0659	secondary active sulfate transmembrane transporter activity
CTM43_RS08535	COG0628	permease
CTM43_RS08560	COG1349	DNA-binding transcription factor activity
CTM43_RS08565	COG0494	nUDIX hydrolase
CTM43_RS08585	COG1061	Type III restriction enzyme res subunit
CTM43_RS08590	COG1187	pseudouridine synthase activity
CTM43_RS08595	COG2814	Major facilitator Superfamily
CTM43_RS08605	COG4172	Belongs to the ABC transporter superfamily
CTM43_RS08610	COG4239	(ABC) transporter, permease
CTM43_RS08615	COG4174	ABC transporter (Permease)
CTM43_RS08620	COG4166	transmembrane transport
CTM43_RS08625	COG2200	EAL domain
CTM43_RS08630	COG0791	NLP P60 protein
CTM43_RS08635	COG0671	phosphoesterase, PA-phosphatase related
CTM43_RS08640	COG0523	cobalamin synthesis protein
CTM43_RS08645	COG0246	Mannitol dehydrogenase
CTM43_RS08650	COG1312	Catalyzes the dehydration of D-mannonate
CTM43_RS08675	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTM43_RS08675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTM43_RS08680	COG1105	Belongs to the carbohydrate kinase PfkB family
CTM43_RS08685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTM43_RS08685	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CTM43_RS08685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTM43_RS08695	COG2855	membrane
CTM43_RS08705	COG0583	DNA-binding transcription factor activity
CTM43_RS08710	COG0833	amino acid
CTM43_RS08725	COG4771	TonB-dependent receptor
CTM43_RS08740	COG2311	Membrane
CTM43_RS08755	COG1129	ABC transporter
CTM43_RS08765	COG2949	membrane
CTM43_RS08775	COG1346	cytolysis
CTM43_RS08785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTM43_RS08790	COG3659	wide pore channel activity
CTM43_RS08805	COG2723	6-phospho-beta-galactosidase activity
CTM43_RS08815	COG1538	Outer membrane efflux protein
CTM43_RS08820	COG0586	Pfam SNARE associated Golgi protein
CTM43_RS08830	COG1686	Belongs to the peptidase S11 family
CTM43_RS08840	COG0277	FAD linked oxidase domain protein
CTM43_RS08845	COG1472	Belongs to the glycosyl hydrolase 3 family
CTM43_RS08850	COG1732	Glycine betaine
CTM43_RS08855	COG1174	glycine betaine transport
CTM43_RS08860	COG1125	glycine betaine transport
CTM43_RS08865	COG1174	glycine betaine transport
CTM43_RS08875	COG3275	phosphorelay sensor kinase activity
CTM43_RS08885	COG4807	Protein conserved in bacteria
CTM43_RS08905	COG5455	response to cobalt ion
CTM43_RS08910	COG0583	DNA-binding transcription factor activity
CTM43_RS08915	COG2252	PERMEase
CTM43_RS08925	COG0583	DNA-binding transcription factor activity
CTM43_RS08945	COG0351	phosphomethylpyrimidine kinase
CTM43_RS08950	COG1830	Aldolase
CTM43_RS08985	COG1070	Carbohydrate kinase
CTM43_RS08995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTM43_RS09005	COG0826	peptidase U32
CTM43_RS09010	COG0745	RESPONSE REGULATOR receiver
CTM43_RS09015	COG2205	protein histidine kinase activity
CTM43_RS09040	COG1301	dicarboxylic acid transport
CTM43_RS09055	COG5002	protein histidine kinase activity
CTM43_RS09060	COG0443	Heat shock 70 kDa protein
CTM43_RS09065	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CTM43_RS09080	COG2982	Protein involved in outer membrane biogenesis
CTM43_RS09085	COG1253	flavin adenine dinucleotide binding
CTM43_RS09215	COG0438	transferase activity, transferring glycosyl groups
CTM43_RS09220	COG1216	Glycosyl transferase, family 2
CTM43_RS09220	COG1442	glycosyl transferase family 8
CTM43_RS09230	COG0463	Glycosyl transferase, family 2
CTM43_RS09255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CTM43_RS09285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTM43_RS09290	COG0583	DNA-binding transcription factor activity
CTM43_RS09300	COG0531	amino acid
CTM43_RS09305	COG0640	Transcriptional regulator
CTM43_RS09310	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CTM43_RS09315	COG2925	Exonuclease
CTM43_RS09330	COG1289	transmembrane transporter activity
CTM43_RS09350	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CTM43_RS09360	COG1942	4-Oxalocrotonate Tautomerase
CTM43_RS09365	COG0583	DNA-binding transcription factor activity
CTM43_RS09370	COG0095	Lipoate-protein ligase
CTM43_RS09375	COG0477	Major facilitator Superfamily
CTM43_RS09390	COG3300	MHYT domain
CTM43_RS09390	COG5001	Diguanylate cyclase
CTM43_RS09395	COG3615	Tellurite resistance protein tehB
CTM43_RS09420	COG3706	GGDEF domain
CTM43_RS09460	COG2197	response regulator
CTM43_RS09480	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTM43_RS09485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTM43_RS09490	COG1960	acyl-CoA dehydrogenase activity
CTM43_RS09520	COG0154	amidase activity
CTM43_RS09545	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CTM43_RS09615	COG3504	Conjugal transfer protein
CTM43_RS09695	COG4771	TonB-dependent receptor
CTM43_RS09700	COG1021	2,3-dihydroxybenzoate-AMP ligase
CTM43_RS09735	COG1132	(ABC) transporter
CTM43_RS09740	COG2814	Major facilitator Superfamily
CTM43_RS09745	COG1169	isochorismate synthase
CTM43_RS09750	COG0582	viral genome integration into host DNA
CTM43_RS09770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTM43_RS09775	COG0735	belongs to the Fur family
CTM43_RS09785	COG0523	cobalamin synthesis protein
CTM43_RS09815	COG0523	cobalamin synthesis protein
CTM43_RS09845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTM43_RS09850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTM43_RS09855	COG1121	(ABC) transporter
CTM43_RS09860	COG0803	Belongs to the bacterial solute-binding protein 9 family
CTM43_RS09865	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CTM43_RS09875	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CTM43_RS09905	COG0803	Belongs to the bacterial solute-binding protein 9 family
CTM43_RS09910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTM43_RS09915	COG1121	(ABC) transporter
CTM43_RS09925	COG0582	viral genome integration into host DNA
CTM43_RS09935	COG0534	Mate efflux family protein
CTM43_RS09945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CTM43_RS09965	COG0604	alcohol dehydrogenase
CTM43_RS09970	COG1309	transcriptional regulator
CTM43_RS09975	COG0025	NhaP-type Na H and K H
CTM43_RS10005	COG0251	oxidation-reduction process
CTM43_RS10025	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CTM43_RS10040	COG1418	mRNA catabolic process
CTM43_RS10045	COG0270	DNA (cytosine-5-)-methyltransferase activity
CTM43_RS10050	COG3727	T/G mismatch-specific endonuclease activity
CTM43_RS10055	COG0697	spore germination
CTM43_RS10060	COG2354	Protein conserved in bacteria
CTM43_RS10090	COG0366	Alpha amylase catalytic
CTM43_RS10095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS10105	COG0765	amino acid transport
CTM43_RS10110	COG1126	abc transporter atp-binding protein
CTM43_RS10115	COG2197	response regulator
CTM43_RS10125	COG2197	response regulator
CTM43_RS10165	COG3318	Belongs to the UPF0149 family
CTM43_RS10165	COG3012	SEC-C Motif Domain Protein
CTM43_RS10170	COG0814	amino acid
CTM43_RS10180	COG1528	Iron-storage protein
CTM43_RS10195	COG0477	Major facilitator Superfamily
CTM43_RS10205	COG2211	Major facilitator Superfamily
CTM43_RS10215	COG1528	Iron-storage protein
CTM43_RS10225	COG1879	ABC-type sugar transport system periplasmic component
CTM43_RS10235	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS10260	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CTM43_RS10270	COG3102	Protein conserved in bacteria
CTM43_RS10290	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CTM43_RS10295	COG1801	Protein of unknown function DUF72
CTM43_RS10300	COG1335	isochorismatase
CTM43_RS10310	COG0494	nUDIX hydrolase
CTM43_RS10335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTM43_RS10345	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CTM43_RS10350	COG0739	heme binding
CTM43_RS10355	COG1560	Kdo2-lipid A biosynthetic process
CTM43_RS10365	COG1737	Transcriptional regulator
CTM43_RS10380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CTM43_RS10385	COG0129	dihydroxy-acid dehydratase activity
CTM43_RS10390	COG0800	Aldolase
CTM43_RS10400	COG3141	response to X-ray
CTM43_RS10405	COG2979	Protein of unknown function (DUF533)
CTM43_RS10410	COG1770	oligopeptidase
CTM43_RS10415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTM43_RS10425	COG2372	response to copper ion
CTM43_RS10430	COG1276	copper resistance
CTM43_RS10445	COG2990	Protein conserved in bacteria
CTM43_RS10470	COG3008	intermembrane lipid transfer
CTM43_RS10475	COG2995	paraquat-inducible protein a
CTM43_RS10480	COG1956	GAF domain-containing protein
CTM43_RS10500	COG2814	Major facilitator Superfamily
CTM43_RS10510	COG1414	Transcriptional regulator
CTM43_RS10550	COG0768	penicillin binding
CTM43_RS10555	COG2226	methyltransferase
CTM43_RS10570	COG3716	PTS system mannose fructose sorbose family IID component
CTM43_RS10575	COG3715	PTS system
CTM43_RS10580	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTM43_RS10580	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTM43_RS10585	COG1253	flavin adenine dinucleotide binding
CTM43_RS10590	COG2200	EAL domain
CTM43_RS10595	COG1760	l-serine dehydratase
CTM43_RS10615	COG0251	oxidation-reduction process
CTM43_RS10620	COG1199	ATP-dependent helicase activity
CTM43_RS10630	COG3065	identical protein binding
CTM43_RS10640	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CTM43_RS10650	COG2894	cell division
CTM43_RS10665	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTM43_RS10695	COG2719	SpoVR family
CTM43_RS10715	COG1619	proteins homologs of microcin C7 resistance protein MccF
CTM43_RS10725	COG4774	siderophore transport
CTM43_RS10740	COG2308	Evidence 4 Homologs of previously reported genes of
CTM43_RS10785	COG0583	DNA-binding transcription factor activity
CTM43_RS10790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTM43_RS10805	COG1882	Formate acetyltransferase
CTM43_RS10835	COG0583	DNA-binding transcription factor activity
CTM43_RS10865	COG0583	DNA-binding transcription factor activity
CTM43_RS10880	COG3122	Protein conserved in bacteria
CTM43_RS10910	COG2885	chlorophyll binding
CTM43_RS10930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CTM43_RS10995	COG0012	GTP binding
CTM43_RS11015	COG0659	secondary active sulfate transmembrane transporter activity
CTM43_RS11045	COG2890	protein-(glutamine-N5) methyltransferase activity
CTM43_RS11065	COG0387	Pfam Sodium calcium exchanger
CTM43_RS11070	COG4572	Cation transport regulator
CTM43_RS11075	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CTM43_RS11085	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CTM43_RS11090	COG3707	response regulator
CTM43_RS11095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTM43_RS11105	COG1116	anion transmembrane transporter activity
CTM43_RS11110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTM43_RS11110	COG2146	nitrite reductase [NAD(P)H] activity
CTM43_RS11115	COG0243	molybdopterin cofactor binding
CTM43_RS11120	COG4932	domain protein
CTM43_RS11125	COG2197	response regulator
CTM43_RS11130	COG3850	Histidine kinase
CTM43_RS11135	COG2223	nitrite transmembrane transporter activity
CTM43_RS11140	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CTM43_RS11145	COG1140	nitrate reductase beta subunit
CTM43_RS11150	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CTM43_RS11155	COG2181	nitrate reductase activity
CTM43_RS11165	COG1522	sequence-specific DNA binding
CTM43_RS11200	COG0788	formyltetrahydrofolate deformylase activity
CTM43_RS11210	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTM43_RS11215	COG0745	RESPONSE REGULATOR receiver
CTM43_RS11220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTM43_RS11225	COG2916	Histone family protein nucleoid-structuring protein H-NS
CTM43_RS11230	COG1435	thymidine kinase activity
CTM43_RS11235	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS11235	COG1454	alcohol dehydrogenase
CTM43_RS11245	COG2095	MarC family integral membrane protein
CTM43_RS11250	COG4166	transmembrane transport
CTM43_RS11255	COG0601	transmembrane transport
CTM43_RS11260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTM43_RS11265	COG0444	Belongs to the ABC transporter superfamily
CTM43_RS11275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTM43_RS11295	COG2353	YceI-like domain
CTM43_RS11305	COG2350	Protein conserved in bacteria
CTM43_RS11315	COG3001	Fructosamine kinase
CTM43_RS11325	COG1105	Belongs to the carbohydrate kinase PfkB family
CTM43_RS11330	COG3137	Salt-induced outer membrane protein
CTM43_RS11375	COG0072	phenylalanine-tRNA ligase activity
CTM43_RS11375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTM43_RS11395	COG0583	DNA-binding transcription factor activity
CTM43_RS11415	COG0386	Belongs to the glutathione peroxidase family
CTM43_RS11425	COG0791	NLP P60 protein
CTM43_RS11435	COG4256	Hemin uptake protein
CTM43_RS11440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTM43_RS11450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CTM43_RS11450	COG0574	Belongs to the PEP-utilizing enzyme family
CTM43_RS11460	COG0628	permease
CTM43_RS11465	COG0277	FAD linked oxidase domain protein
CTM43_RS11465	COG0247	lactate metabolic process
CTM43_RS11470	COG2050	protein possibly involved in aromatic compounds catabolism
CTM43_RS11475	COG2261	transglycosylase associated protein
CTM43_RS11505	COG1120	ATPase activity
CTM43_RS11510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTM43_RS11520	COG0583	DNA-binding transcription factor activity
CTM43_RS11545	COG1304	FMN binding
CTM43_RS11550	COG1309	transcriptional regulator
CTM43_RS11565	COG0316	Belongs to the HesB IscA family
CTM43_RS11570	COG0719	Fe-S assembly protein
CTM43_RS11575	COG0396	ATPase activity
CTM43_RS11580	COG0719	Fe-S assembly protein
CTM43_RS11595	COG1376	ErfK ybiS ycfS ynhG family protein
CTM43_RS11620	COG1309	transcriptional regulator
CTM43_RS11625	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CTM43_RS11625	COG1082	Xylose isomerase domain protein TIM barrel
CTM43_RS11630	COG2271	Major facilitator Superfamily
CTM43_RS11635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CTM43_RS11645	COG1120	ATPase activity
CTM43_RS11650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTM43_RS11655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTM43_RS11660	COG1414	Transcriptional regulator
CTM43_RS11695	COG2814	Major facilitator Superfamily
CTM43_RS11715	COG0583	DNA-binding transcription factor activity
CTM43_RS11720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTM43_RS11740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTM43_RS11745	COG1116	anion transmembrane transporter activity
CTM43_RS11750	COG4774	siderophore transport
CTM43_RS11755	COG1120	ATPase activity
CTM43_RS11760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTM43_RS11765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTM43_RS11785	COG0765	amino acid transport
CTM43_RS11790	COG1126	abc transporter atp-binding protein
CTM43_RS11820	COG1473	amidohydrolase
CTM43_RS11825	COG3383	formate dehydrogenase (NAD+) activity
CTM43_RS11830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CTM43_RS11845	COG1175	transmembrane transport
CTM43_RS11875	COG4133	protoheme IX ABC transporter activity
CTM43_RS11880	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CTM43_RS11885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CTM43_RS11900	COG1138	Cytochrome C-type biogenesis protein
CTM43_RS11905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTM43_RS11910	COG4235	cytochrome complex assembly
CTM43_RS11910	COG3088	subunit of a heme lyase
CTM43_RS11930	COG5002	protein histidine kinase activity
CTM43_RS11930	COG3850	Histidine kinase
CTM43_RS11935	COG0745	RESPONSE REGULATOR receiver
CTM43_RS11955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTM43_RS11990	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS11995	COG2610	gluconate transmembrane transporter activity
CTM43_RS12000	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTM43_RS12010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTM43_RS12020	COG0583	DNA-binding transcription factor activity
CTM43_RS12050	COG2814	Major facilitator Superfamily
CTM43_RS12065	COG0277	FAD linked oxidase domain protein
CTM43_RS12070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTM43_RS12095	COG0402	S-adenosylhomocysteine deaminase activity
CTM43_RS12135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTM43_RS12145	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS12150	COG0531	amino acid
CTM43_RS12180	COG4608	Belongs to the ABC transporter superfamily
CTM43_RS12185	COG0444	Belongs to the ABC transporter superfamily
CTM43_RS12210	COG0346	lactoylglutathione lyase activity
CTM43_RS12215	COG1349	DNA-binding transcription factor activity
CTM43_RS12245	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CTM43_RS12265	COG0300	oxidoreductase activity
CTM43_RS12315	COG0307	riboflavin synthase, alpha
CTM43_RS12320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTM43_RS12325	COG2814	Major facilitator Superfamily
CTM43_RS12330	COG0583	DNA-binding transcription factor activity
CTM43_RS12345	COG2814	Major facilitator Superfamily
CTM43_RS12360	COG0791	NLP P60 protein
CTM43_RS12365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CTM43_RS12375	COG0346	lactoylglutathione lyase activity
CTM43_RS12380	COG1902	pentaerythritol trinitrate reductase activity
CTM43_RS12385	COG1309	transcriptional regulator
CTM43_RS12390	COG3313	Fe-S protein
CTM43_RS12395	COG4989	oxidoreductase activity
CTM43_RS12400	COG2032	superoxide dismutase activity
CTM43_RS12405	COG1289	transmembrane transporter activity
CTM43_RS12410	COG1566	PFAM secretion protein HlyD family protein
CTM43_RS12425	COG3706	GGDEF domain
CTM43_RS12440	COG3895	Periplasmic Protein
CTM43_RS12455	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CTM43_RS12460	COG0625	glutathione transferase activity
CTM43_RS12475	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTM43_RS12485	COG4659	FMN binding
CTM43_RS12520	COG2723	6-phospho-beta-galactosidase activity
CTM43_RS12530	COG0673	inositol 2-dehydrogenase activity
CTM43_RS12540	COG2814	Major facilitator Superfamily
CTM43_RS12560	COG3038	cytochrome b561
CTM43_RS12580	COG0583	DNA-binding transcription factor activity
CTM43_RS12585	COG3485	protocatechuate 3,4-dioxygenase
CTM43_RS12590	COG3485	protocatechuate 3,4-dioxygenase
CTM43_RS12595	COG5383	Protein conserved in bacteria
CTM43_RS12600	COG2272	Belongs to the type-B carboxylesterase lipase family
CTM43_RS12615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTM43_RS12620	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTM43_RS12625	COG1275	C4-dicarboxylate transporter malic acid transport protein
CTM43_RS12630	COG0500	methyltransferase
CTM43_RS12640	COG0697	spore germination
CTM43_RS12645	COG2207	Transcriptional regulator
CTM43_RS12645	COG3708	Transcriptional regulator
CTM43_RS12650	COG3135	benzoate transporter
CTM43_RS12655	COG1396	sequence-specific DNA binding
CTM43_RS12665	COG0826	peptidase U32
CTM43_RS12685	COG1294	oxidase, subunit
CTM43_RS12690	COG1271	oxidase subunit
CTM43_RS12695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTM43_RS12700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CTM43_RS12705	COG3842	ATPase activity
CTM43_RS12710	COG1176	ABC-type spermidine putrescine transport system, permease component I
CTM43_RS12715	COG1177	transmembrane transport
CTM43_RS12720	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS12750	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS12755	COG0747	negative chemotaxis
CTM43_RS12765	COG3238	Protein conserved in bacteria
CTM43_RS12770	COG1247	-acetyltransferase
CTM43_RS12780	COG2130	NADP-dependent
CTM43_RS12795	COG3691	Protein conserved in bacteria
CTM43_RS12800	COG1228	amidohydrolase
CTM43_RS12805	COG4772	TonB-dependent receptor
CTM43_RS12830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CTM43_RS12835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTM43_RS12840	COG1473	amidohydrolase
CTM43_RS12845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTM43_RS12850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS12860	COG0765	amino acid transport
CTM43_RS12865	COG1126	abc transporter atp-binding protein
CTM43_RS12875	COG0625	glutathione transferase activity
CTM43_RS12890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTM43_RS12895	COG3842	ATPase activity
CTM43_RS12900	COG1840	ABC-type Fe3 transport system, periplasmic component
CTM43_RS12905	COG1178	ABC-type Fe3 transport system permease component
CTM43_RS12910	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CTM43_RS12915	COG2181	nitrate reductase activity
CTM43_RS12920	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CTM43_RS12925	COG1140	nitrate reductase beta subunit
CTM43_RS12930	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CTM43_RS12950	COG1414	Transcriptional regulator
CTM43_RS12960	COG4829	muconolactone delta-isomerase
CTM43_RS12965	COG3485	protocatechuate 3,4-dioxygenase
CTM43_RS12975	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTM43_RS12995	COG3383	formate dehydrogenase (NAD+) activity
CTM43_RS12995	COG0243	molybdopterin cofactor binding
CTM43_RS13000	COG0243	molybdopterin cofactor binding
CTM43_RS13000	COG3383	formate dehydrogenase (NAD+) activity
CTM43_RS13005	COG0437	4 iron, 4 sulfur cluster binding
CTM43_RS13010	COG2864	formate dehydrogenase
CTM43_RS13025	COG2326	polyphosphate kinase activity
CTM43_RS13035	COG2814	Major facilitator Superfamily
CTM43_RS13045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTM43_RS13055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTM43_RS13065	COG0747	negative chemotaxis
CTM43_RS13070	COG1064	alcohol dehydrogenase
CTM43_RS13085	COG0488	(ABC) transporter
CTM43_RS13125	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS13130	COG3729	General stress protein
CTM43_RS13145	COG3685	Protein conserved in bacteria
CTM43_RS13155	COG0366	Alpha amylase catalytic
CTM43_RS13165	COG2323	membrane
CTM43_RS13175	COG3111	PFAM Bacterial OB fold (BOF) protein
CTM43_RS13180	COG1764	response to oxidative stress
CTM43_RS13205	COG3781	membrane
CTM43_RS13210	COG0243	molybdopterin cofactor binding
CTM43_RS13215	COG0583	DNA-binding transcription factor activity
CTM43_RS13220	COG1447	Phosphotransferase system cellobiose-specific component IIA
CTM43_RS13225	COG2814	Major facilitator Superfamily
CTM43_RS13235	COG1285	pathogenesis
CTM43_RS13240	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CTM43_RS13260	COG0519	Catalyzes the synthesis of GMP from XMP
CTM43_RS13260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTM43_RS13300	COG0596	Alpha beta hydrolase
CTM43_RS13310	COG2205	protein histidine kinase activity
CTM43_RS13330	COG0076	glutamate decarboxylase activity
CTM43_RS13335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTM43_RS13340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTM43_RS13345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTM43_RS13350	COG1116	anion transmembrane transporter activity
CTM43_RS13355	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTM43_RS13370	COG0673	inositol 2-dehydrogenase activity
CTM43_RS13380	COG1609	Transcriptional regulator
CTM43_RS13405	COG0402	S-adenosylhomocysteine deaminase activity
CTM43_RS13410	COG1953	Uracil, thiamine, allantoin
CTM43_RS13445	COG0596	Alpha beta hydrolase
CTM43_RS13455	COG2207	Transcriptional regulator
CTM43_RS13475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTM43_RS13540	COG0765	amino acid transport
CTM43_RS13550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CTM43_RS13560	COG2070	2-Nitropropane dioxygenase
CTM43_RS13565	COG0583	DNA-binding transcription factor activity
CTM43_RS13575	COG1902	pentaerythritol trinitrate reductase activity
CTM43_RS13580	COG4529	Protein conserved in bacteria
CTM43_RS13585	COG0477	Major facilitator Superfamily
CTM43_RS13610	COG2223	nitrite transmembrane transporter activity
CTM43_RS13620	COG1609	Transcriptional regulator
CTM43_RS13625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTM43_RS13635	COG3037	sugar-specific permease SgaT UlaA
CTM43_RS13640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTM43_RS13650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTM43_RS13655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTM43_RS13655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTM43_RS13655	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CTM43_RS13670	COG0583	DNA-binding transcription factor activity
CTM43_RS13680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTM43_RS13690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTM43_RS13730	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CTM43_RS13730	COG0456	acetyltransferase
CTM43_RS13740	COG0667	Aldo Keto reductase
CTM43_RS13745	COG0667	Aldo Keto reductase
CTM43_RS13750	COG3386	PFAM SMP-30 Gluconolaconase
CTM43_RS13755	COG0667	Aldo Keto reductase
CTM43_RS13775	COG2076	Multidrug Resistance protein
CTM43_RS13780	COG0583	DNA-binding transcription factor activity
CTM43_RS13795	COG0583	DNA-binding transcription factor activity
CTM43_RS13800	COG2315	Protein conserved in bacteria
CTM43_RS13855	COG1929	Belongs to the glycerate kinase type-1 family
CTM43_RS13860	COG3835	regulator
CTM43_RS13880	COG2186	Transcriptional regulator
CTM43_RS13885	COG1263	PTS System
CTM43_RS13885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTM43_RS13895	COG2814	Major facilitator Superfamily
CTM43_RS13900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTM43_RS13900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTM43_RS13910	COG2819	hydrolase of the alpha beta superfamily
CTM43_RS13915	COG5001	Diguanylate cyclase
CTM43_RS13915	COG3300	MHYT domain
CTM43_RS13950	COG3188	usher protein
CTM43_RS13965	COG1649	PFAM Uncharacterised BCR, COG1649
CTM43_RS13970	COG3550	peptidyl-serine autophosphorylation
CTM43_RS13975	COG1396	sequence-specific DNA binding
CTM43_RS13980	COG2351	hydroxyisourate hydrolase activity
CTM43_RS13985	COG3195	allantoin biosynthetic process
CTM43_RS13985	COG3648	Uricase
CTM43_RS13990	COG2233	PERMEase
CTM43_RS14020	COG2207	Transcriptional regulator
CTM43_RS14035	COG4628	conserved protein (DUF2132)
CTM43_RS14055	COG2011	ABC-type metal ion transport system permease component
CTM43_RS14060	COG2070	2-Nitropropane dioxygenase
CTM43_RS14070	COG0477	Major facilitator Superfamily
CTM43_RS14150	COG2199	diguanylate cyclase activity
CTM43_RS14165	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS14170	COG0583	DNA-binding transcription factor activity
CTM43_RS14180	COG0039	L-malate dehydrogenase activity
CTM43_RS14185	COG1349	DNA-binding transcription factor activity
CTM43_RS14190	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CTM43_RS14195	COG3395	kinase activity
CTM43_RS14205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTM43_RS14220	COG2731	YhcH YjgK YiaL family protein
CTM43_RS14225	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS14250	COG4977	sequence-specific DNA binding
CTM43_RS14260	COG0697	spore germination
CTM43_RS14265	COG2814	Major facilitator Superfamily
CTM43_RS14295	COG0683	leucine binding
CTM43_RS14300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CTM43_RS14335	COG2223	nitrite transmembrane transporter activity
CTM43_RS14340	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CTM43_RS14355	COG1349	DNA-binding transcription factor activity
CTM43_RS14360	COG2084	Dehydrogenase
CTM43_RS14365	COG3395	kinase activity
CTM43_RS14370	COG0235	Class ii aldolase
CTM43_RS14375	COG3622	Belongs to the hyi family
CTM43_RS14380	COG2610	gluconate transmembrane transporter activity
CTM43_RS14385	COG2207	Transcriptional regulator
CTM43_RS14385	COG3708	Transcriptional regulator
CTM43_RS14400	COG2200	EAL domain
CTM43_RS14405	COG1546	Belongs to the CinA family
CTM43_RS14410	COG0071	Belongs to the small heat shock protein (HSP20) family
CTM43_RS14430	COG2135	peptidase activity
CTM43_RS14435	COG2207	Transcriptional regulator
CTM43_RS14450	COG4221	oxidoreductase activity
CTM43_RS14455	COG1802	Transcriptional regulator
CTM43_RS14460	COG0589	response to stress
CTM43_RS14465	COG0246	Mannitol dehydrogenase
CTM43_RS14470	COG2271	Major facilitator Superfamily
CTM43_RS14485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTM43_RS14500	COG0243	molybdopterin cofactor binding
CTM43_RS14505	COG0437	4 iron, 4 sulfur cluster binding
CTM43_RS14510	COG3302	dmso reductase anchor subunit
CTM43_RS14525	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CTM43_RS14530	COG1940	carbohydrate kinase activity
CTM43_RS14535	COG0583	DNA-binding transcription factor activity
CTM43_RS14540	COG2814	Major facilitator Superfamily
CTM43_RS14545	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CTM43_RS14555	COG3591	Belongs to the peptidase S1B family
CTM43_RS14575	COG0628	permease
CTM43_RS14605	COG0679	Auxin Efflux Carrier
CTM43_RS14615	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CTM43_RS14640	COG3290	protein histidine kinase activity
CTM43_RS14645	COG4565	transcriptional regulatory protein
CTM43_RS14670	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTM43_RS14670	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTM43_RS14695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTM43_RS14700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTM43_RS14710	COG0183	Belongs to the thiolase family
CTM43_RS14715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTM43_RS14725	COG1414	Transcriptional regulator
CTM43_RS14730	COG2840	Smr protein MutS2
CTM43_RS14735	COG0583	DNA-binding transcription factor activity
CTM43_RS14745	COG1473	amidohydrolase
CTM43_RS14750	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CTM43_RS14765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTM43_RS14780	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CTM43_RS14785	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CTM43_RS14805	COG0531	amino acid
CTM43_RS14815	COG3136	membrane protein required for alginate biosynthesis
CTM43_RS14820	COG0745	RESPONSE REGULATOR receiver
CTM43_RS14830	COG2205	protein histidine kinase activity
CTM43_RS14840	COG0114	fumarate hydratase activity
CTM43_RS14845	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTM43_RS14845	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTM43_RS14850	COG1482	cell wall glycoprotein biosynthetic process
CTM43_RS14855	COG5339	Protein conserved in bacteria
CTM43_RS14860	COG1609	Transcriptional regulator
CTM43_RS14865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTM43_RS14865	COG1263	PTS System
CTM43_RS14870	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CTM43_RS14895	COG2391	methyltransferase activity
CTM43_RS14900	COG0425	Belongs to the sulfur carrier protein TusA family
CTM43_RS14905	COG5562	phage envelope protein
CTM43_RS14910	COG0401	homolog of Blt101
CTM43_RS14915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CTM43_RS14920	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS14925	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CTM43_RS14935	COG1113	amino acid transport
CTM43_RS14940	COG2988	succinylglutamate desuccinylase activity
CTM43_RS14945	COG3724	N-succinylarginine dihydrolase activity
CTM43_RS14950	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS14955	COG3138	arginine N-succinyltransferase
CTM43_RS14960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTM43_RS14965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTM43_RS14970	COG0667	Aldo Keto reductase
CTM43_RS14975	COG0583	DNA-binding transcription factor activity
CTM43_RS15000	COG4122	O-methyltransferase activity
CTM43_RS15005	COG1643	Atp-dependent helicase
CTM43_RS15020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTM43_RS15025	COG3327	negative regulation of DNA-templated transcription, initiation
CTM43_RS15030	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CTM43_RS15035	COG0183	Belongs to the thiolase family
CTM43_RS15040	COG2050	protein possibly involved in aromatic compounds catabolism
CTM43_RS15045	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTM43_RS15050	COG1024	Enoyl-CoA hydratase
CTM43_RS15055	COG1024	Enoyl-CoA hydratase
CTM43_RS15060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTM43_RS15065	COG2151	metal-sulfur cluster biosynthetic enzyme
CTM43_RS15070	COG3396	Phenylacetate-CoA oxygenase
CTM43_RS15075	COG3460	Phenylacetate-CoA oxygenase
CTM43_RS15080	COG3396	Phenylacetate-CoA oxygenase
CTM43_RS15085	COG2030	dehydratase
CTM43_RS15085	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS15110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTM43_RS15125	COG2072	flavoprotein involved in K transport
CTM43_RS15130	COG0583	DNA-binding transcription factor activity
CTM43_RS15140	COG1126	abc transporter atp-binding protein
CTM43_RS15150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS15165	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS15170	COG2207	Transcriptional regulator
CTM43_RS15175	COG3784	Protein of unknown function (DUF1318)
CTM43_RS15185	COG2911	Protein conserved in bacteria
CTM43_RS15190	COG0586	Pfam SNARE associated Golgi protein
CTM43_RS15195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CTM43_RS15200	COG3187	Heat shock protein
CTM43_RS15205	COG3042	response to heat
CTM43_RS15215	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTM43_RS15215	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CTM43_RS15215	COG1013	pyruvate-flavodoxin oxidoreductase activity
CTM43_RS15215	COG0674	pyruvate-flavodoxin oxidoreductase activity
CTM43_RS15220	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CTM43_RS15230	COG0589	response to stress
CTM43_RS15240	COG0513	Belongs to the DEAD box helicase family
CTM43_RS15255	COG1349	DNA-binding transcription factor activity
CTM43_RS15260	COG0673	inositol 2-dehydrogenase activity
CTM43_RS15275	COG1113	amino acid transport
CTM43_RS15280	COG1522	sequence-specific DNA binding
CTM43_RS15290	COG1448	Aminotransferase
CTM43_RS15295	COG2011	ABC-type metal ion transport system permease component
CTM43_RS15315	COG1078	dGTPase activity
CTM43_RS15320	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS15325	COG0583	DNA-binding transcription factor activity
CTM43_RS15345	COG0656	L-ascorbic acid biosynthetic process
CTM43_RS15370	COG4166	transmembrane transport
CTM43_RS15375	COG2866	Carboxypeptidase
CTM43_RS15380	COG4948	Mandelate Racemase Muconate Lactonizing
CTM43_RS15385	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CTM43_RS15390	COG3180	Ammonia monooxygenase
CTM43_RS15400	COG1486	melibiose metabolic process
CTM43_RS15405	COG0583	DNA-binding transcription factor activity
CTM43_RS15415	COG3106	COG3106 Predicted ATPase
CTM43_RS15425	COG1983	PspC domain protein
CTM43_RS15435	COG1842	Phage shock protein A
CTM43_RS15440	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CTM43_RS15450	COG1473	amidohydrolase
CTM43_RS15465	COG0702	epimerase
CTM43_RS15480	COG4171	peptide transport system, permease
CTM43_RS15495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTM43_RS15505	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CTM43_RS15510	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTM43_RS15510	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTM43_RS15525	COG1349	DNA-binding transcription factor activity
CTM43_RS15535	COG0023	Translation Initiation Factor
CTM43_RS15545	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CTM43_RS15550	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CTM43_RS15555	COG0671	phosphoesterase, PA-phosphatase related
CTM43_RS15565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CTM43_RS15595	COG0616	signal peptide processing
CTM43_RS15605	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS15610	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CTM43_RS15620	COG0583	DNA-binding transcription factor activity
CTM43_RS15630	COG0009	L-threonylcarbamoyladenylate synthase
CTM43_RS15640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CTM43_RS15645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTM43_RS15645	COG0512	Glutamine amidotransferase of anthranilate synthase
CTM43_RS15650	COG0134	indole-3-glycerol-phosphate synthase activity
CTM43_RS15650	COG0135	phosphoribosylanthranilate isomerase activity
CTM43_RS15685	COG4774	siderophore transport
CTM43_RS15695	COG3047	cAMP biosynthetic process
CTM43_RS15700	COG0727	PFAM Uncharacterised protein family (UPF0153)
CTM43_RS15730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTM43_RS15735	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS15740	COG1988	membrane-bound metal-dependent
CTM43_RS15745	COG1823	symporter activity
CTM43_RS15755	COG0753	catalase activity
CTM43_RS15765	COG1486	melibiose metabolic process
CTM43_RS15770	COG1917	Cupin 2, conserved barrel domain protein
CTM43_RS15770	COG2169	Transcriptional regulator
CTM43_RS15775	COG1447	Phosphotransferase system cellobiose-specific component IIA
CTM43_RS15780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTM43_RS15785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTM43_RS15790	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTM43_RS15800	COG0322	excinuclease ABC activity
CTM43_RS15805	COG3678	ATP-independent chaperone mediated protein folding
CTM43_RS15815	COG3724	N-succinylarginine dihydrolase activity
CTM43_RS15825	COG3138	arginine N-succinyltransferase
CTM43_RS15835	COG0708	Exodeoxyribonuclease III
CTM43_RS15840	COG0398	Pfam SNARE associated Golgi protein
CTM43_RS15845	COG0398	Pfam SNARE associated Golgi protein
CTM43_RS15850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTM43_RS15855	COG4134	Bacterial extracellular solute-binding protein
CTM43_RS15860	COG4135	transport system, permease component
CTM43_RS15865	COG4136	ATPase activity
CTM43_RS15870	COG2897	thiosulfate sulfurtransferase activity
CTM43_RS15875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTM43_RS15885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTM43_RS15890	COG3321	synthase
CTM43_RS15890	COG0604	alcohol dehydrogenase
CTM43_RS15890	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS15895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CTM43_RS15900	COG0709	Synthesizes selenophosphate from selenide and ATP
CTM43_RS15920	COG0778	Nitroreductase
CTM43_RS15925	COG0616	signal peptide processing
CTM43_RS15930	COG0252	asparaginase activity
CTM43_RS15935	COG1335	isochorismatase
CTM43_RS15950	COG3139	Protein of unknown function (DUF1315)
CTM43_RS15970	COG0656	L-ascorbic acid biosynthetic process
CTM43_RS15975	COG3713	MltA-interacting MipA family protein
CTM43_RS15980	COG2766	serine protein kinase
CTM43_RS15995	COG0386	Belongs to the glutathione peroxidase family
CTM43_RS16015	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS16020	COG0583	DNA-binding transcription factor activity
CTM43_RS16025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTM43_RS16030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTM43_RS16045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CTM43_RS16055	COG2207	Transcriptional regulator
CTM43_RS16060	COG2807	transmembrane transport
CTM43_RS16065	COG0504	CTP synthase activity
CTM43_RS16070	COG1683	Conserved Protein
CTM43_RS16075	COG3189	MarR family transcriptional regulator
CTM43_RS16080	COG3042	response to heat
CTM43_RS16085	COG2199	diguanylate cyclase activity
CTM43_RS16085	COG2203	Gaf domain
CTM43_RS16105	COG3182	Iron-regulated membrane protein
CTM43_RS16115	COG1560	Kdo2-lipid A biosynthetic process
CTM43_RS16130	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CTM43_RS16135	COG3706	GGDEF domain
CTM43_RS16140	COG0583	DNA-binding transcription factor activity
CTM43_RS16145	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CTM43_RS16170	COG1294	oxidase, subunit
CTM43_RS16175	COG1271	oxidase subunit
CTM43_RS16180	COG3546	catalase activity
CTM43_RS16185	COG3685	Protein conserved in bacteria
CTM43_RS16190	COG3685	Protein conserved in bacteria
CTM43_RS16195	COG3729	General stress protein
CTM43_RS16200	COG1063	alcohol dehydrogenase
CTM43_RS16205	COG3813	Protein conserved in bacteria
CTM43_RS16225	COG0640	Transcriptional regulator
CTM43_RS16230	COG0538	isocitrate dehydrogenase activity
CTM43_RS16240	COG3300	MHYT domain
CTM43_RS16240	COG5001	Diguanylate cyclase
CTM43_RS16245	COG3706	GGDEF domain
CTM43_RS16260	COG0582	viral genome integration into host DNA
CTM43_RS16265	COG0538	isocitrate dehydrogenase activity
CTM43_RS16270	COG1187	pseudouridine synthase activity
CTM43_RS16290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTM43_RS16310	COG2205	protein histidine kinase activity
CTM43_RS16315	COG2850	peptidyl-arginine hydroxylation
CTM43_RS16335	COG1177	transmembrane transport
CTM43_RS16350	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CTM43_RS16360	COG0318	PFAM AMP-dependent synthetase and ligase
CTM43_RS16365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTM43_RS16370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTM43_RS16375	COG0698	ribose 5-phosphate isomerase
CTM43_RS16390	COG3395	kinase activity
CTM43_RS16400	COG0149	triose-phosphate isomerase activity
CTM43_RS16405	COG2390	Transcriptional regulator
CTM43_RS16415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CTM43_RS16425	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTM43_RS16435	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTM43_RS16440	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTM43_RS16445	COG1376	ErfK ybiS ycfS ynhG family protein
CTM43_RS16445	COG1388	LysM domain
CTM43_RS16455	COG1309	transcriptional regulator
CTM43_RS16465	COG3134	Outer membrane lipoprotein
CTM43_RS16470	COG1252	NADH dehydrogenase
CTM43_RS16495	COG5633	Lipoprotein
CTM43_RS16500	COG0537	adenosine 5'-monophosphoramidase activity
CTM43_RS16510	COG0084	hydrolase, TatD family'
CTM43_RS16515	COG0470	DNA polymerase III
CTM43_RS16525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTM43_RS16530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CTM43_RS16535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTM43_RS16550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CTM43_RS16570	COG1399	metal-binding, possibly nucleic acid-binding protein
CTM43_RS16590	COG1530	ribonuclease E activity
CTM43_RS16595	COG0583	DNA-binding transcription factor activity
CTM43_RS16600	COG2814	Major facilitator Superfamily
CTM43_RS16620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTM43_RS16670	COG1560	Kdo2-lipid A biosynthetic process
CTM43_RS16690	COG5645	(Lipo)protein
CTM43_RS16730	COG3381	protein complex oligomerization
CTM43_RS16755	COG1309	transcriptional regulator
CTM43_RS16760	COG0583	DNA-binding transcription factor activity
CTM43_RS16770	COG1335	isochorismatase
CTM43_RS16780	COG1702	phosphate starvation-inducible protein PhoH
CTM43_RS16800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CTM43_RS16810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTM43_RS16825	COG1309	transcriptional regulator
CTM43_RS16860	COG2233	PERMEase
CTM43_RS16870	COG3729	General stress protein
CTM43_RS16895	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS16910	COG0531	amino acid
CTM43_RS16920	COG0174	glutamine synthetase
CTM43_RS16925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CTM43_RS16930	COG1917	Cupin 2, conserved barrel domain protein
CTM43_RS16930	COG1396	sequence-specific DNA binding
CTM43_RS16935	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS16940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTM43_RS16945	COG0583	DNA-binding transcription factor activity
CTM43_RS16950	COG0473	3-isopropylmalate dehydrogenase activity
CTM43_RS16955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTM43_RS16960	COG4638	Rieske (2fe-2S)
CTM43_RS16965	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS16970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTM43_RS16980	COG2200	EAL domain
CTM43_RS16985	COG2200	EAL domain
CTM43_RS17000	COG0670	Belongs to the BI1 family
CTM43_RS17050	COG2207	Transcriptional regulator
CTM43_RS17055	COG1881	PFAM PEBP family protein
CTM43_RS17070	COG1832	CoA-binding protein
CTM43_RS17080	COG0210	DNA helicase
CTM43_RS17085	COG3304	Inner membrane component domain
CTM43_RS17090	COG1289	transmembrane transporter activity
CTM43_RS17095	COG3070	regulator of competence-specific genes
CTM43_RS17120	COG1067	ATP-dependent peptidase activity
CTM43_RS17130	COG3130	regulation of translation
CTM43_RS17135	COG3009	Protein conserved in bacteria
CTM43_RS17140	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CTM43_RS17140	COG3008	intermembrane lipid transfer
CTM43_RS17145	COG2995	paraquat-inducible protein a
CTM43_RS17150	COG0488	(ABC) transporter
CTM43_RS17160	COG3217	Mosc domain protein beta barrel domain protein
CTM43_RS17160	COG0633	Ferredoxin
CTM43_RS17175	COG0431	NADPH-dependent FMN reductase
CTM43_RS17180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTM43_RS17185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTM43_RS17190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTM43_RS17200	COG0308	aminopeptidase N
CTM43_RS17210	COG1473	amidohydrolase
CTM43_RS17220	COG0814	amino acid
CTM43_RS17230	COG1522	sequence-specific DNA binding
CTM43_RS17240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CTM43_RS17245	COG1448	Aminotransferase
CTM43_RS17250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTM43_RS17255	COG3108	Peptidase M15
CTM43_RS17260	COG2989	Protein conserved in bacteria
CTM43_RS17270	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CTM43_RS17280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTM43_RS17285	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CTM43_RS17290	COG3173	Aminoglycoside phosphotransferase
CTM43_RS17305	COG3214	Protein conserved in bacteria
CTM43_RS17320	COG0658	competence protein
CTM43_RS17320	COG2333	competence protein COMEC
CTM43_RS17330	COG0539	negative regulation of cytoplasmic translation
CTM43_RS17350	COG2323	membrane
CTM43_RS17355	COG1944	ATP diphosphatase activity
CTM43_RS17360	COG2116	formate transmembrane transporter activity
CTM43_RS17365	COG1882	Formate acetyltransferase
CTM43_RS17370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CTM43_RS17375	COG0477	Major facilitator Superfamily
CTM43_RS17385	COG3302	dmso reductase anchor subunit
CTM43_RS17390	COG0437	4 iron, 4 sulfur cluster binding
CTM43_RS17395	COG0243	molybdopterin cofactor binding
CTM43_RS17405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTM43_RS17415	COG1674	ftsk spoiiie
CTM43_RS17415	COG1178	ABC-type Fe3 transport system permease component
CTM43_RS17425	COG0492	ferredoxin-NADP+ reductase activity
CTM43_RS17430	COG4988	ABC transporter
CTM43_RS17435	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CTM43_RS17450	COG0542	response to heat
CTM43_RS17460	COG1278	Cold shock
CTM43_RS17470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTM43_RS17475	COG3593	DNA synthesis involved in DNA repair
CTM43_RS17485	COG2431	L-lysine efflux transmembrane transporter activity
CTM43_RS17495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTM43_RS17510	COG0028	Belongs to the TPP enzyme family
CTM43_RS17515	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CTM43_RS17520	COG0702	epimerase
CTM43_RS17525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTM43_RS17530	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTM43_RS17535	COG4251	negative regulation of phosphorylation
CTM43_RS17535	COG5001	Diguanylate cyclase
CTM43_RS17535	COG3706	GGDEF domain
CTM43_RS17535	COG2203	Gaf domain
CTM43_RS17550	COG1126	abc transporter atp-binding protein
CTM43_RS17555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS17560	COG4215	(ABC) transporter
CTM43_RS17565	COG4160	amino acid transport
CTM43_RS17570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS17575	COG5002	protein histidine kinase activity
CTM43_RS17580	COG0745	RESPONSE REGULATOR receiver
CTM43_RS17595	COG1177	transmembrane transport
CTM43_RS17600	COG1176	ABC-type spermidine putrescine transport system, permease component I
CTM43_RS17605	COG3842	ATPase activity
CTM43_RS17610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CTM43_RS17625	COG0778	Nitroreductase
CTM43_RS17665	COG3226	Transcriptional regulator
CTM43_RS17670	COG0738	Major facilitator superfamily
CTM43_RS17675	COG0561	phosphatase activity
CTM43_RS17680	COG2814	Major facilitator Superfamily
CTM43_RS17690	COG0671	phosphoesterase, PA-phosphatase related
CTM43_RS17695	COG1349	DNA-binding transcription factor activity
CTM43_RS17700	COG1686	Belongs to the peptidase S11 family
CTM43_RS17705	COG0625	glutathione transferase activity
CTM43_RS17710	COG2133	pyrroloquinoline quinone binding
CTM43_RS17720	COG2223	nitrite transmembrane transporter activity
CTM43_RS17745	COG0747	negative chemotaxis
CTM43_RS17755	COG1446	asparaginase
CTM43_RS17760	COG0303	'Molybdopterin
CTM43_RS17765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CTM43_RS17770	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CTM43_RS17775	COG1882	Formate acetyltransferase
CTM43_RS17780	COG0561	phosphatase activity
CTM43_RS17790	COG1609	Transcriptional regulator
CTM43_RS17795	COG2271	Major facilitator Superfamily
CTM43_RS17810	COG0488	(ABC) transporter
CTM43_RS17815	COG2365	Tyrosine phosphatase family
CTM43_RS17820	COG1376	ErfK ybiS ycfS ynhG family protein
CTM43_RS17825	COG2188	Transcriptional regulator
CTM43_RS17830	COG2723	6-phospho-beta-galactosidase activity
CTM43_RS17835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CTM43_RS17850	COG2194	sulfuric ester hydrolase activity
CTM43_RS17855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CTM43_RS17870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS17875	COG0765	amino acid transport
CTM43_RS17880	COG1126	abc transporter atp-binding protein
CTM43_RS17885	COG0668	transmembrane transport
CTM43_RS17895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTM43_RS17905	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CTM43_RS17915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTM43_RS17920	COG1199	ATP-dependent helicase activity
CTM43_RS17925	COG0513	Belongs to the DEAD box helicase family
CTM43_RS17930	COG3958	Transketolase
CTM43_RS17935	COG3959	Transketolase, thiamine diphosphate binding domain
CTM43_RS17940	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS17945	COG2271	Major facilitator Superfamily
CTM43_RS17950	COG0583	DNA-binding transcription factor activity
CTM43_RS17955	COG1309	transcriptional regulator
CTM43_RS17960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTM43_RS17965	COG1131	(ABC) transporter
CTM43_RS17970	COG0842	Transport permease protein
CTM43_RS17975	COG0842	Transport permease protein
CTM43_RS17985	COG3568	Endonuclease Exonuclease Phosphatase
CTM43_RS17990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTM43_RS17995	COG0392	lysyltransferase activity
CTM43_RS18000	COG0670	Belongs to the BI1 family
CTM43_RS18005	COG0314	molybdopterin synthase activity
CTM43_RS18010	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CTM43_RS18020	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTM43_RS18045	COG0745	RESPONSE REGULATOR receiver
CTM43_RS18050	COG0642	Histidine kinase
CTM43_RS18090	COG2226	methyltransferase
CTM43_RS18105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CTM43_RS18110	COG1881	PFAM PEBP family protein
CTM43_RS18150	COG4677	pectinesterase activity
CTM43_RS18160	COG0589	response to stress
CTM43_RS18165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTM43_RS18195	COG0789	Transcriptional regulator
CTM43_RS18200	COG2200	EAL domain
CTM43_RS18225	COG0561	phosphatase activity
CTM43_RS18235	COG4149	molybdate abc transporter
CTM43_RS18240	COG0725	ABC transporter, periplasmic molybdate-binding protein
CTM43_RS18250	COG3585	molybdate ion transport
CTM43_RS18250	COG2005	Transcriptional regulator
CTM43_RS18255	COG1119	ATPase activity
CTM43_RS18265	COG1085	galactose-1-phosphate uridylyltransferase
CTM43_RS18275	COG2017	converts alpha-aldose to the beta-anomer
CTM43_RS18285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTM43_RS18300	COG3201	nicotinamide mononucleotide transporter
CTM43_RS18305	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CTM43_RS18355	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CTM43_RS18360	COG2885	chlorophyll binding
CTM43_RS18370	COG3064	Membrane
CTM43_RS18375	COG0848	biopolymer transport protein
CTM43_RS18380	COG0811	peptide transport
CTM43_RS18385	COG0824	Thioesterase
CTM43_RS18390	COG3790	cyd operon protein YbgE
CTM43_RS18395	COG4890	Cyd operon protein YbgT
CTM43_RS18400	COG1294	oxidase, subunit
CTM43_RS18405	COG1271	oxidase subunit
CTM43_RS18415	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CTM43_RS18430	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTM43_RS18435	COG0567	Dehydrogenase, E1 component
CTM43_RS18440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTM43_RS18445	COG1053	succinate dehydrogenase
CTM43_RS18450	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CTM43_RS18455	COG2009	succinate dehydrogenase
CTM43_RS18490	COG1984	allophanate hydrolase subunit 2
CTM43_RS18495	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CTM43_RS18510	COG0415	Belongs to the DNA photolyase family
CTM43_RS18540	COG2205	protein histidine kinase activity
CTM43_RS18545	COG0745	RESPONSE REGULATOR receiver
CTM43_RS18555	COG0033	Phosphoglucomutase
CTM43_RS18565	COG0596	Alpha beta hydrolase
CTM43_RS18580	COG0735	belongs to the Fur family
CTM43_RS18620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CTM43_RS18625	COG1846	Transcriptional regulator
CTM43_RS18625	COG1940	carbohydrate kinase activity
CTM43_RS18630	COG0647	UMP catabolic process
CTM43_RS18635	COG0367	asparagine synthase
CTM43_RS18680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTM43_RS18690	COG1702	phosphate starvation-inducible protein PhoH
CTM43_RS18715	COG0765	amino acid transport
CTM43_RS18720	COG0765	amino acid transport
CTM43_RS18725	COG1126	abc transporter atp-binding protein
CTM43_RS18740	COG2888	peptidyl-tyrosine sulfation
CTM43_RS18755	COG1466	dna polymerase III delta subunit
CTM43_RS18770	COG0799	negative regulation of ribosome biogenesis
CTM43_RS18780	COG0768	penicillin binding
CTM43_RS18785	COG0772	Belongs to the SEDS family
CTM43_RS18790	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTM43_RS18795	COG1686	Belongs to the peptidase S11 family
CTM43_RS18810	COG0583	DNA-binding transcription factor activity
CTM43_RS18825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTM43_RS18845	COG3069	C4-dicarboxylate transmembrane transporter activity
CTM43_RS18850	COG3719	Belongs to the RNase T2 family
CTM43_RS18855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTM43_RS18875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTM43_RS18880	COG0583	DNA-binding transcription factor activity
CTM43_RS18885	COG3969	phosphoadenosine phosphosulfate
CTM43_RS18890	COG1475	DNA binding
CTM43_RS18895	COG0436	Aminotransferase
CTM43_RS18920	COG1129	ABC transporter
CTM43_RS18925	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS18930	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS18940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTM43_RS18955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTM43_RS18965	COG0402	S-adenosylhomocysteine deaminase activity
CTM43_RS18975	COG0483	inositol monophosphate 1-phosphatase activity
CTM43_RS18980	COG2271	Major facilitator Superfamily
CTM43_RS19010	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS19015	COG1129	ABC transporter
CTM43_RS19020	COG0371	Dehydrogenase
CTM43_RS19040	COG2879	small protein
CTM43_RS19045	COG1966	Carbon starvation protein
CTM43_RS19055	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS19060	COG1535	isochorismatase
CTM43_RS19060	COG3433	isochorismatase activity
CTM43_RS19065	COG1021	2,3-dihydroxybenzoate-AMP ligase
CTM43_RS19070	COG1169	isochorismate synthase
CTM43_RS19075	COG4592	Periplasmic binding protein
CTM43_RS19085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTM43_RS19090	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTM43_RS19095	COG1120	ATPase activity
CTM43_RS19100	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CTM43_RS19100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTM43_RS19105	COG3251	PFAM MbtH domain protein
CTM43_RS19110	COG2382	esterase
CTM43_RS19120	COG4771	TonB-dependent receptor
CTM43_RS19125	COG2977	Belongs to the P-Pant transferase superfamily
CTM43_RS19130	COG3958	Transketolase
CTM43_RS19135	COG3959	Transketolase, thiamine diphosphate binding domain
CTM43_RS19145	COG2390	Transcriptional regulator
CTM43_RS19150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTM43_RS19155	COG1879	ABC-type sugar transport system periplasmic component
CTM43_RS19165	COG1129	ABC transporter
CTM43_RS19170	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS19180	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS19190	COG0583	DNA-binding transcription factor activity
CTM43_RS19195	COG0668	transmembrane transport
CTM43_RS19205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTM43_RS19230	COG0747	negative chemotaxis
CTM43_RS19235	COG0601	transmembrane transport
CTM43_RS19240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTM43_RS19245	COG0444	Belongs to the ABC transporter superfamily
CTM43_RS19250	COG4608	Belongs to the ABC transporter superfamily
CTM43_RS19265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CTM43_RS19270	COG4221	oxidoreductase activity
CTM43_RS19280	COG4215	(ABC) transporter
CTM43_RS19290	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CTM43_RS19305	COG0697	spore germination
CTM43_RS19320	COG4608	Belongs to the ABC transporter superfamily
CTM43_RS19325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTM43_RS19335	COG4166	transmembrane transport
CTM43_RS19345	COG3698	Phosphodiester glycosidase
CTM43_RS19390	COG2315	Protein conserved in bacteria
CTM43_RS19395	COG0778	Nitroreductase
CTM43_RS19405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTM43_RS19415	COG3716	PTS system mannose fructose sorbose family IID component
CTM43_RS19420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTM43_RS19425	COG2222	sugar isomerase
CTM43_RS19430	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CTM43_RS19430	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CTM43_RS19450	COG0477	Major facilitator Superfamily
CTM43_RS19455	COG0668	transmembrane transport
CTM43_RS19460	COG1609	Transcriptional regulator
CTM43_RS19470	COG0673	inositol 2-dehydrogenase activity
CTM43_RS19480	COG2211	Major facilitator Superfamily
CTM43_RS19485	COG1113	amino acid transport
CTM43_RS19500	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS19505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTM43_RS19515	COG0531	amino acid
CTM43_RS19530	COG4680	protein conserved in bacteria
CTM43_RS19580	COG0667	Aldo Keto reductase
CTM43_RS19585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS19590	COG1473	amidohydrolase
CTM43_RS19610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTM43_RS19615	COG1120	ATPase activity
CTM43_RS19620	COG1566	PFAM secretion protein HlyD family protein
CTM43_RS19665	COG4211	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS19670	COG1129	ABC transporter
CTM43_RS19685	COG0673	inositol 2-dehydrogenase activity
CTM43_RS19720	COG3104	oligopeptide transport
CTM43_RS19725	COG1982	Orn Lys Arg decarboxylase major
CTM43_RS19730	COG0531	amino acid
CTM43_RS19735	COG3710	Transcriptional regulator
CTM43_RS19745	COG1560	Kdo2-lipid A biosynthetic process
CTM43_RS19760	COG3188	usher protein
CTM43_RS19765	COG3121	Chaperone
CTM43_RS19770	COG3539	Fimbrial protein
CTM43_RS19970	COG5410	chromosome segregation
CTM43_RS19995	COG3772	lysozyme
CTM43_RS20150	COG0582	viral genome integration into host DNA
CTM43_RS20170	COG2501	S4 domain
CTM43_RS20180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTM43_RS20195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CTM43_RS20200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CTM43_RS20215	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CTM43_RS20220	COG4181	ATPase activity
CTM43_RS20225	COG2755	lipolytic protein G-D-S-L family
CTM43_RS20230	COG0300	oxidoreductase activity
CTM43_RS20235	COG3118	belongs to the thioredoxin family
CTM43_RS20245	COG0390	transport system, permease component
CTM43_RS20250	COG4619	ABC transporter
CTM43_RS20255	COG0330	HflC and HflK could
CTM43_RS20260	COG1585	Membrane protein implicated in regulation of membrane protease activity
CTM43_RS20275	COG3735	TraB family
CTM43_RS20280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CTM43_RS20290	COG2223	nitrite transmembrane transporter activity
CTM43_RS20295	COG4651	solute:proton antiporter activity
CTM43_RS20295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTM43_RS20300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTM43_RS20340	COG2832	Protein of unknown function (DUF454)
CTM43_RS20345	COG3923	Primosomal replication protein n
CTM43_RS20355	COG5464	transposase or invertase
CTM43_RS20360	COG3264	Mechanosensitive ion channel
CTM43_RS20360	COG1196	nuclear chromosome segregation
CTM43_RS20365	COG1309	transcriptional regulator
CTM43_RS20370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTM43_RS20375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTM43_RS20390	COG0110	maltose O-acetyltransferase activity
CTM43_RS20435	COG1874	Beta-galactosidase
CTM43_RS20440	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CTM43_RS20445	COG3833	ABC-type maltose transport systems, permease component
CTM43_RS20450	COG1175	transmembrane transport
CTM43_RS20465	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CTM43_RS20480	COG2364	Membrane
CTM43_RS20510	COG3695	enzyme binding
CTM43_RS20515	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CTM43_RS20520	COG1946	Acyl-CoA thioesterase
CTM43_RS20525	COG0004	ammonium transporteR
CTM43_RS20530	COG0347	Belongs to the P(II) protein family
CTM43_RS20535	COG1132	(ABC) transporter
CTM43_RS20540	COG1132	(ABC) transporter
CTM43_RS20545	COG1522	sequence-specific DNA binding
CTM43_RS20560	COG4533	DNA binding
CTM43_RS20570	COG0824	Thioesterase
CTM43_RS20575	COG1555	photosystem II stabilization
CTM43_RS20580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTM43_RS20585	COG0776	regulation of translation
CTM43_RS20590	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CTM43_RS20620	COG0271	Belongs to the BolA IbaG family
CTM43_RS20625	COG3056	Lipoprotein
CTM43_RS20630	COG2223	nitrite transmembrane transporter activity
CTM43_RS20635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CTM43_RS20640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTM43_RS20645	COG1845	cytochrome c oxidase, subunit III
CTM43_RS20650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CTM43_RS20665	COG1414	Transcriptional regulator
CTM43_RS20670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CTM43_RS20675	COG1053	succinate dehydrogenase
CTM43_RS20685	COG1053	succinate dehydrogenase
CTM43_RS20700	COG0673	inositol 2-dehydrogenase activity
CTM43_RS20705	COG2814	Major facilitator Superfamily
CTM43_RS20715	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CTM43_RS20740	COG0142	geranyltranstransferase activity
CTM43_RS20750	COG0667	Aldo Keto reductase
CTM43_RS20755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CTM43_RS20775	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTM43_RS20775	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTM43_RS20785	COG4238	major outer membrane lipoprotein
CTM43_RS20805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTM43_RS20810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTM43_RS20815	COG1862	Preprotein translocase
CTM43_RS20835	COG0450	alkyl hydroperoxide reductase
CTM43_RS20840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTM43_RS20855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTM43_RS20865	COG1228	amidohydrolase
CTM43_RS20875	COG1335	isochorismatase
CTM43_RS20880	COG0583	DNA-binding transcription factor activity
CTM43_RS20885	COG0366	Alpha amylase catalytic
CTM43_RS20910	COG0420	3'-5' exonuclease activity
CTM43_RS20915	COG0419	ATPase involved in DNA repair
CTM43_RS20920	COG1940	carbohydrate kinase activity
CTM43_RS20935	COG4126	flavin adenine dinucleotide binding
CTM43_RS20945	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CTM43_RS20950	COG3416	Protein conserved in bacteria
CTM43_RS20960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CTM43_RS20970	COG1785	Belongs to the alkaline phosphatase family
CTM43_RS21010	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CTM43_RS21015	COG1335	isochorismatase
CTM43_RS21020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTM43_RS21025	COG0113	porphobilinogen synthase activity
CTM43_RS21035	COG2175	clavaminate synthase activity
CTM43_RS21040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTM43_RS21045	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CTM43_RS21050	COG4521	taurine ABC transporter
CTM43_RS21055	COG2040	homocysteine
CTM43_RS21060	COG0833	amino acid
CTM43_RS21070	COG4303	Ethanolamine ammonia lyase large subunit
CTM43_RS21075	COG4302	ethanolamine ammonia-lyase activity
CTM43_RS21110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS21115	COG1126	abc transporter atp-binding protein
CTM43_RS21120	COG4597	amino acid ABC transporter
CTM43_RS21125	COG0765	amino acid transport
CTM43_RS21140	COG3188	usher protein
CTM43_RS21165	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CTM43_RS21175	COG3639	organic phosphonate transmembrane transporter activity
CTM43_RS21205	COG0791	NLP P60 protein
CTM43_RS21240	COG0765	amino acid transport
CTM43_RS21250	COG4221	oxidoreductase activity
CTM43_RS21265	COG0436	Aminotransferase
CTM43_RS21270	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CTM43_RS21275	COG1984	allophanate hydrolase subunit 2
CTM43_RS21290	COG0697	spore germination
CTM43_RS21295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTM43_RS21300	COG0439	Biotin carboxylase
CTM43_RS21305	COG0511	ligase activity, forming carbon-carbon bonds
CTM43_RS21315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CTM43_RS21320	COG0022	dehydrogenase e1 component
CTM43_RS21325	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTM43_RS21330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTM43_RS21340	COG0625	glutathione transferase activity
CTM43_RS21345	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CTM43_RS21365	COG0579	oxidoreductase
CTM43_RS21370	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS21375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTM43_RS21380	COG1113	amino acid transport
CTM43_RS21385	COG1802	Transcriptional regulator
CTM43_RS21405	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTM43_RS21410	COG0454	-acetyltransferase
CTM43_RS21425	COG2991	Protein conserved in bacteria
CTM43_RS21440	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CTM43_RS21445	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CTM43_RS21465	COG3034	peptidoglycan biosynthetic process
CTM43_RS21470	COG0121	glutamine amidotransferase
CTM43_RS21480	COG1960	acyl-CoA dehydrogenase activity
CTM43_RS21485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTM43_RS21495	COG0583	DNA-binding transcription factor activity
CTM43_RS21505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTM43_RS21515	COG2226	methyltransferase
CTM43_RS21525	COG1388	LysM domain
CTM43_RS21525	COG0741	lytic transglycosylase activity
CTM43_RS21530	COG2226	methyltransferase
CTM43_RS21540	COG2814	Major facilitator Superfamily
CTM43_RS21545	COG0583	DNA-binding transcription factor activity
CTM43_RS21550	COG0656	L-ascorbic acid biosynthetic process
CTM43_RS21585	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CTM43_RS21595	COG2011	ABC-type metal ion transport system permease component
CTM43_RS21600	COG1464	Belongs to the NlpA lipoprotein family
CTM43_RS21610	COG1720	tRNA m6t6A37 methyltransferase activity
CTM43_RS21620	COG0791	NLP P60 protein
CTM43_RS21625	COG3015	lipoprotein NlpE involved in copper resistance
CTM43_RS21630	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CTM43_RS21645	COG4568	rho-dependent transcription termination
CTM43_RS21655	COG0346	lactoylglutathione lyase activity
CTM43_RS21660	COG1982	Orn Lys Arg decarboxylase major
CTM43_RS21700	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CTM43_RS21710	COG0750	zinc metalloprotease
CTM43_RS21715	COG0575	Belongs to the CDS family
CTM43_RS21730	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CTM43_RS21755	COG0024	Methionine aminopeptidase
CTM43_RS21760	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CTM43_RS21775	COG3835	regulator
CTM43_RS21780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTM43_RS21800	COG2860	membrane
CTM43_RS21820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTM43_RS21825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTM43_RS21830	COG1120	ATPase activity
CTM43_RS21835	COG4774	siderophore transport
CTM43_RS21840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTM43_RS21925	COG1643	Atp-dependent helicase
CTM43_RS21930	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CTM43_RS21950	COG0617	tRNA 3'-terminal CCA addition
CTM43_RS21955	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTM43_RS21975	COG0726	polysaccharide deacetylase
CTM43_RS21980	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTM43_RS21985	COG0842	Transport permease protein
CTM43_RS21990	COG1131	(ABC) transporter
CTM43_RS21995	COG0288	reversible hydration of carbon dioxide
CTM43_RS22005	COG4993	Dehydrogenase
CTM43_RS22010	COG2132	Multicopper oxidase
CTM43_RS22055	COG3064	Membrane
CTM43_RS22070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTM43_RS22075	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTM43_RS22080	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CTM43_RS22085	COG2186	Transcriptional regulator
CTM43_RS22090	COG1113	amino acid transport
CTM43_RS22095	COG2211	Major facilitator Superfamily
CTM43_RS22100	COG3940	Belongs to the glycosyl hydrolase 43 family
CTM43_RS22105	COG3725	Membrane protein required for beta-lactamase induction
CTM43_RS22110	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTM43_RS22120	COG4969	Belongs to the N-Me-Phe pilin family
CTM43_RS22125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CTM43_RS22130	COG1459	type II secretion system
CTM43_RS22155	COG0494	nUDIX hydrolase
CTM43_RS22175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CTM43_RS22180	COG0849	cell division
CTM43_RS22205	COG0772	Belongs to the SEDS family
CTM43_RS22220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTM43_RS22225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CTM43_RS22230	COG0768	penicillin binding
CTM43_RS22250	COG1609	Transcriptional regulator
CTM43_RS22260	COG0028	Belongs to the TPP enzyme family
CTM43_RS22310	COG0738	Major facilitator superfamily
CTM43_RS22320	COG0583	DNA-binding transcription factor activity
CTM43_RS22325	COG2271	Major facilitator Superfamily
CTM43_RS22330	COG2814	Major facilitator Superfamily
CTM43_RS22350	COG1178	ABC-type Fe3 transport system permease component
CTM43_RS22360	COG0586	Pfam SNARE associated Golgi protein
CTM43_RS22380	COG0235	Class ii aldolase
CTM43_RS22385	COG0417	DNA replication proofreading
CTM43_RS22395	COG0564	pseudouridine synthase activity
CTM43_RS22410	COG3493	citrate carrier protein
CTM43_RS22425	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CTM43_RS22430	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CTM43_RS22440	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CTM43_RS22490	COG0505	Belongs to the CarA family
CTM43_RS22555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CTM43_RS22565	COG3152	Membrane
CTM43_RS22580	COG1047	Peptidyl-prolyl cis-trans
CTM43_RS22595	COG0196	riboflavin kinase activity
CTM43_RS22610	COG0583	DNA-binding transcription factor activity
CTM43_RS22635	COG4735	regulation of single-species biofilm formation
CTM43_RS22640	COG1584	GPR1 FUN34 yaaH family protein
CTM43_RS22645	COG0477	Major facilitator Superfamily
CTM43_RS22650	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTM43_RS22655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTM43_RS22660	COG1115	amino acid carrier protein
CTM43_RS22680	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTM43_RS22690	COG0527	aspartate kinase activity
CTM43_RS22690	COG0460	homoserine dehydrogenase
CTM43_RS22700	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CTM43_RS22710	COG0745	RESPONSE REGULATOR receiver
CTM43_RS22715	COG4452	Inner membrane protein CreD
CTM43_RS22720	COG2205	protein histidine kinase activity
CTM43_RS22725	COG0745	RESPONSE REGULATOR receiver
CTM43_RS22730	COG3045	CreA protein
CTM43_RS22735	COG2207	Transcriptional regulator
CTM43_RS22735	COG3708	Transcriptional regulator
CTM43_RS22755	COG0741	lytic transglycosylase activity
CTM43_RS22760	COG0488	(ABC) transporter
CTM43_RS22770	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CTM43_RS22775	COG0560	Phosphoserine phosphatase
CTM43_RS22785	COG3726	membrane protein affecting hemolysin expression
CTM43_RS22815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CTM43_RS22820	COG0084	hydrolase, TatD family'
CTM43_RS22825	COG4667	esterase of the alpha-beta hydrolase superfamily
CTM43_RS22835	COG2823	Periplasmic or secreted lipoprotein
CTM43_RS22845	COG1011	Hydrolase
CTM43_RS22850	COG0456	acetyltransferase
CTM43_RS22855	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CTM43_RS22885	COG3706	GGDEF domain
CTM43_RS22890	COG4114	ferric iron reductase
CTM43_RS22895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTM43_RS22895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTM43_RS22900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CTM43_RS22905	COG2197	response regulator
CTM43_RS22910	COG2197	response regulator
CTM43_RS22930	COG2966	Psort location CytoplasmicMembrane, score
CTM43_RS22945	COG1484	DNA-dependent DNA replication
CTM43_RS22960	COG5464	transposase or invertase
CTM43_RS22970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTM43_RS22975	COG3716	PTS system mannose fructose sorbose family IID component
CTM43_RS22980	COG3715	PTS system
CTM43_RS22995	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CTM43_RS22995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CTM43_RS23000	COG0456	acetyltransferase
CTM43_RS23000	COG1214	PFAM Peptidase M22, glycoprotease
CTM43_RS23010	COG1737	Transcriptional regulator
CTM43_RS23015	COG0800	Aldolase
CTM43_RS23020	COG3734	2-keto-3-deoxy-galactonokinase
CTM43_RS23035	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CTM43_RS23065	COG1846	Transcriptional regulator
CTM43_RS23075	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTM43_RS23085	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS23090	COG3384	dioxygenase
CTM43_RS23100	COG3971	2-oxopent-4-enoate hydratase activity
CTM43_RS23120	COG2368	4-hydroxyphenylacetate
CTM43_RS23125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTM43_RS23140	COG1966	Carbon starvation protein
CTM43_RS23145	COG2879	small protein
CTM43_RS23150	COG0523	cobalamin synthesis protein
CTM43_RS23160	COG1012	belongs to the aldehyde dehydrogenase family
CTM43_RS23165	COG5464	transposase or invertase
CTM43_RS23170	COG2207	Transcriptional regulator
CTM43_RS23170	COG1917	Cupin 2, conserved barrel domain protein
CTM43_RS23180	COG2733	membrane
CTM43_RS23195	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CTM43_RS23200	COG1924	4 iron, 4 sulfur cluster binding
CTM43_RS23215	COG1566	PFAM secretion protein HlyD family protein
CTM43_RS23225	COG5457	Domain of unknown function (DUF1127)
CTM43_RS23230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTM43_RS23240	COG0583	DNA-binding transcription factor activity
CTM43_RS23245	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTM43_RS23255	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS23260	COG1129	ABC transporter
CTM43_RS23265	COG1879	ABC-type sugar transport system periplasmic component
CTM43_RS23275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTM43_RS23280	COG0842	Transport permease protein
CTM43_RS23280	COG1129	ABC transporter
CTM43_RS23285	COG0842	Transport permease protein
CTM43_RS23320	COG2850	peptidyl-arginine hydroxylation
CTM43_RS23335	COG5002	protein histidine kinase activity
CTM43_RS23340	COG0745	RESPONSE REGULATOR receiver
CTM43_RS23350	COG1538	Outer membrane efflux protein
CTM43_RS23355	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTM43_RS23360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTM43_RS23365	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTM43_RS23375	COG3040	lipid binding
CTM43_RS23380	COG0789	Transcriptional regulator
CTM43_RS23390	COG0300	oxidoreductase activity
CTM43_RS23405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTM43_RS23425	COG3272	Protein of unknown function (DUF1722)
CTM43_RS23430	COG4580	involved in the transport of maltose and maltodextrins
CTM43_RS23435	COG2115	Belongs to the xylose isomerase family
CTM43_RS23440	COG2211	Major facilitator Superfamily
CTM43_RS23445	COG3507	Belongs to the glycosyl hydrolase 43 family
CTM43_RS23455	COG0584	glycerophosphoryl diester phosphodiesterase
CTM43_RS23465	COG1176	ABC-type spermidine putrescine transport system, permease component I
CTM43_RS23520	COG1216	Glycosyl transferase, family 2
CTM43_RS23570	COG1401	restriction endodeoxyribonuclease activity
CTM43_RS23625	COG2815	serine threonine protein kinase
CTM43_RS23625	COG0515	serine threonine protein kinase
CTM43_RS23630	COG0582	viral genome integration into host DNA
CTM43_RS23645	COG0288	reversible hydration of carbon dioxide
CTM43_RS23650	COG0659	secondary active sulfate transmembrane transporter activity
CTM43_RS23655	COG1064	alcohol dehydrogenase
CTM43_RS23660	COG1175	transmembrane transport
CTM43_RS23665	COG0395	ABC-type sugar transport system, permease component
CTM43_RS23670	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTM43_RS23675	COG3842	ATPase activity
CTM43_RS23680	COG1653	transport
CTM43_RS23690	COG1082	Xylose isomerase domain protein TIM barrel
CTM43_RS23700	COG3962	Belongs to the TPP enzyme family
CTM43_RS23705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTM43_RS23710	COG1737	Transcriptional regulator
CTM43_RS23710	COG0837	glucose binding
CTM43_RS23725	COG3718	enzyme involved in inositol metabolism
CTM43_RS23740	COG0433	COG0433 Predicted ATPase
CTM43_RS23745	COG0795	lipopolysaccharide-transporting ATPase activity
CTM43_RS23750	COG0795	lipopolysaccharide-transporting ATPase activity
CTM43_RS23765	COG2927	DNA polymerase III (CHI subunit)
CTM43_RS23770	COG0525	valine-tRNA ligase activity
CTM43_RS23795	COG2188	Transcriptional regulator
CTM43_RS23800	COG1288	antiporter activity
CTM43_RS23805	COG1228	amidohydrolase
CTM43_RS23810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTM43_RS23815	COG2222	sugar isomerase
CTM43_RS23820	COG2731	YhcH YjgK YiaL family protein
CTM43_RS23865	COG1263	PTS System
CTM43_RS23865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTM43_RS23870	COG0366	Alpha amylase catalytic
CTM43_RS23875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTM43_RS23880	COG1486	melibiose metabolic process
CTM43_RS23905	COG0602	queuosine metabolic process
CTM43_RS23915	COG3077	Addiction module antitoxin, RelB DinJ family
CTM43_RS23920	COG3711	transcriptional antiterminator
CTM43_RS23920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTM43_RS23925	COG2706	6-phosphogluconolactonase activity
CTM43_RS23940	COG3964	amidohydrolase
CTM43_RS23975	COG0312	modulator of DNA gyrase
CTM43_RS23995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTM43_RS24005	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS24010	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS24015	COG1129	ABC transporter
CTM43_RS24020	COG1879	ABC-type sugar transport system periplasmic component
CTM43_RS24040	COG2105	PFAM AIG2 family protein
CTM43_RS24045	COG2911	Protein conserved in bacteria
CTM43_RS24050	COG0729	surface antigen
CTM43_RS24060	COG1253	flavin adenine dinucleotide binding
CTM43_RS24085	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CTM43_RS24100	COG1733	regulation of RNA biosynthetic process
CTM43_RS24105	COG0702	epimerase
CTM43_RS24115	COG0697	spore germination
CTM43_RS24125	COG1113	amino acid transport
CTM43_RS24130	COG0545	Peptidyl-prolyl cis-trans isomerase
CTM43_RS24135	COG3061	Opacity-associated protein A
CTM43_RS24145	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CTM43_RS24150	COG2965	DNA replication, synthesis of RNA primer
CTM43_RS24210	COG1073	alpha beta
CTM43_RS24215	COG3650	response to hydrogen peroxide
CTM43_RS24225	COG1960	acyl-CoA dehydrogenase activity
CTM43_RS24230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTM43_RS24235	COG0557	exoribonuclease II activity
CTM43_RS24250	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CTM43_RS24260	COG0330	HflC and HflK could
CTM43_RS24265	COG0330	HflC and HflK could
CTM43_RS24270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTM43_RS24290	COG0860	N-Acetylmuramoyl-L-alanine amidase
CTM43_RS24295	COG0802	atpase or kinase
CTM43_RS24300	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTM43_RS24300	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CTM43_RS24305	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CTM43_RS24330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTM43_RS24355	COG3264	Mechanosensitive ion channel
CTM43_RS24355	COG1511	domain protein
CTM43_RS24370	COG1053	succinate dehydrogenase
CTM43_RS24375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTM43_RS24395	COG2076	Multidrug Resistance protein
CTM43_RS24400	COG5510	response to toxic substance
CTM43_RS24415	COG1509	lysine 2,3-aminomutase activity
CTM43_RS24485	COG0531	amino acid
CTM43_RS24490	COG3030	protein affecting phage T7 exclusion by the F plasmid
CTM43_RS24500	COG1027	Aspartate ammonia-lyase
CTM43_RS24505	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CTM43_RS24520	COG1309	transcriptional regulator
CTM43_RS24550	COG0457	Tetratricopeptide repeat
CTM43_RS24555	COG1649	PFAM Uncharacterised BCR, COG1649
CTM43_RS24555	COG0726	polysaccharide deacetylase
CTM43_RS24560	COG1215	transferase activity, transferring glycosyl groups
CTM43_RS24580	COG0861	Integral membrane protein TerC family
CTM43_RS24610	COG1486	melibiose metabolic process
CTM43_RS24620	COG2169	Transcriptional regulator
CTM43_RS24635	COG2824	Alkylphosphonate utilization operon protein PhnA
CTM43_RS24640	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CTM43_RS24645	COG2188	Transcriptional regulator
CTM43_RS24650	COG3624	Phosphonate C-P lyase system protein PhnG
CTM43_RS24655	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CTM43_RS24660	COG3626	phosphonate metabolism
CTM43_RS24665	COG3627	carbon phosphorus lyase activity
CTM43_RS24670	COG4107	phosphonate C-P lyase system protein PhnK
CTM43_RS24675	COG4778	phosphonate C-P lyase system protein PhnL
CTM43_RS24680	COG3454	Phosphonate metabolism
CTM43_RS24690	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CTM43_RS24700	COG4191	Histidine kinase
CTM43_RS24700	COG0784	Response regulator, receiver
CTM43_RS24705	COG1129	ABC transporter
CTM43_RS24710	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS24745	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CTM43_RS24750	COG1301	dicarboxylic acid transport
CTM43_RS24760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTM43_RS24770	COG3162	membrane
CTM43_RS24800	COG3539	Fimbrial protein
CTM43_RS24805	COG1346	cytolysis
CTM43_RS24810	COG1380	Effector of murein hydrolase LrgA
CTM43_RS24815	COG0583	DNA-binding transcription factor activity
CTM43_RS24820	COG0025	NhaP-type Na H and K H
CTM43_RS24825	COG2252	PERMEase
CTM43_RS24830	COG0625	glutathione transferase activity
CTM43_RS24835	COG0789	Transcriptional regulator
CTM43_RS24845	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CTM43_RS24880	COG1234	tRNA 3'-trailer cleavage
CTM43_RS24885	COG1609	Transcriptional regulator
CTM43_RS24890	COG0483	inositol monophosphate 1-phosphatase activity
CTM43_RS24905	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTM43_RS24925	COG4771	TonB-dependent receptor
CTM43_RS24930	COG0741	lytic transglycosylase activity
CTM43_RS24950	COG2315	Protein conserved in bacteria
CTM43_RS24955	COG0432	Pfam Uncharacterised protein family UPF0047
CTM43_RS24970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTM43_RS24975	COG0305	Participates in initiation and elongation during chromosome replication
CTM43_RS24990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTM43_RS25000	COG0735	belongs to the Fur family
CTM43_RS25005	COG3237	CsbD-like
CTM43_RS25010	COG0534	Mate efflux family protein
CTM43_RS25020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CTM43_RS25095	COG0251	oxidation-reduction process
CTM43_RS25105	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CTM43_RS25125	COG0527	aspartate kinase activity
CTM43_RS25180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CTM43_RS25210	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTM43_RS25220	COG0456	acetyltransferase
CTM43_RS25250	COG0151	Belongs to the GarS family
CTM43_RS25260	COG4191	Histidine kinase
CTM43_RS25265	COG3678	ATP-independent chaperone mediated protein folding
CTM43_RS25300	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CTM43_RS25315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CTM43_RS25320	COG2104	thiamine diphosphate biosynthetic process
CTM43_RS25335	COG3706	GGDEF domain
CTM43_RS25345	COG1447	Phosphotransferase system cellobiose-specific component IIA
CTM43_RS25350	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CTM43_RS25385	COG0250	Participates in transcription elongation, termination and antitermination
CTM43_RS25435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CTM43_RS25465	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CTM43_RS25475	COG1739	Uncharacterized protein family UPF0029
CTM43_RS25520	COG0805	protein transport
CTM43_RS25540	COG3165	ubiquinone biosynthetic process from chorismate
CTM43_RS25570	COG0583	DNA-binding transcription factor activity
CTM43_RS25575	COG0697	spore germination
CTM43_RS25580	COG0561	phosphatase activity
CTM43_RS25585	COG2267	carboxylic ester hydrolase activity
CTM43_RS25590	COG1280	lysine exporter protein (LysE YggA)
CTM43_RS25600	COG1280	lysine exporter protein (LysE YggA)
CTM43_RS25635	COG0210	DNA helicase
CTM43_RS25640	COG1011	Hydrolase
CTM43_RS25670	COG3072	Adenylate cyclase
CTM43_RS25685	COG2959	enzyme of heme biosynthesis
CTM43_RS25690	COG3071	HemY protein
CTM43_RS25735	COG2244	polysaccharide biosynthetic process
CTM43_RS25740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CTM43_RS25745	COG0456	acetyltransferase
CTM43_RS25750	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CTM43_RS25755	COG1088	dTDP-glucose 4,6-dehydratase activity
CTM43_RS25760	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CTM43_RS25765	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CTM43_RS25775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTM43_RS25780	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CTM43_RS25790	COG3118	belongs to the thioredoxin family
CTM43_RS25820	COG1811	Na channel or pump
CTM43_RS25830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTM43_RS25835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTM43_RS25845	COG0583	DNA-binding transcription factor activity
CTM43_RS25850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTM43_RS25865	COG3978	acetolactate synthase activity
CTM43_RS25885	COG3085	chromosome segregation
CTM43_RS25960	COG0583	DNA-binding transcription factor activity
CTM43_RS25985	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CTM43_RS26000	COG3443	Belongs to the bacterial solute-binding protein 9 family
CTM43_RS26005	COG2207	Transcriptional regulator
CTM43_RS26015	COG0371	Dehydrogenase
CTM43_RS26020	COG0697	spore germination
CTM43_RS26030	COG0583	DNA-binding transcription factor activity
CTM43_RS26040	COG0737	Belongs to the 5'-nucleotidase family
CTM43_RS26050	COG0460	homoserine dehydrogenase
CTM43_RS26050	COG0527	aspartate kinase activity
CTM43_RS26055	COG0626	cystathionine gamma-synthase activity
CTM43_RS26070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTM43_RS26075	COG1609	Transcriptional regulator
CTM43_RS26080	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTM43_RS26095	COG1575	Belongs to the MenA family. Type 1 subfamily
CTM43_RS26115	COG3678	ATP-independent chaperone mediated protein folding
CTM43_RS26120	COG0745	RESPONSE REGULATOR receiver
CTM43_RS26125	COG2205	protein histidine kinase activity
CTM43_RS26130	COG2258	MOSC domain
CTM43_RS26135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTM43_RS26180	COG1129	ABC transporter
CTM43_RS26185	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS26190	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTM43_RS26195	COG1454	alcohol dehydrogenase
CTM43_RS26205	COG2211	Major facilitator Superfamily
CTM43_RS26265	COG0205	6-phosphofructokinase activity
CTM43_RS26280	COG3383	formate dehydrogenase (NAD+) activity
CTM43_RS26280	COG0243	molybdopterin cofactor binding
CTM43_RS26285	COG3383	formate dehydrogenase (NAD+) activity
CTM43_RS26285	COG0243	molybdopterin cofactor binding
CTM43_RS26290	COG0437	4 iron, 4 sulfur cluster binding
CTM43_RS26295	COG2864	formate dehydrogenase
CTM43_RS26310	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTM43_RS26320	COG0456	acetyltransferase
CTM43_RS26335	COG1011	Hydrolase
CTM43_RS26350	COG3852	Histidine kinase
CTM43_RS26360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTM43_RS26385	COG3436	PFAM IS66 Orf2 family protein
CTM43_RS26390	COG4372	Transposase
CTM43_RS26485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTM43_RS26510	COG2144	transferase activity, transferring acyl groups
CTM43_RS26525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTM43_RS26550	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
CTM43_RS26580	COG4245	von Willebrand factor, type A
CTM43_RS26585	COG4245	von Willebrand factor, type A
CTM43_RS26595	COG4245	von Willebrand factor, type A
CTM43_RS26615	COG1358	cellular component organization or biogenesis
CTM43_RS26710	COG3321	synthase
CTM43_RS26710	COG1028	Short-chain dehydrogenase reductase Sdr
CTM43_RS26710	COG0604	alcohol dehydrogenase
CTM43_RS26740	COG1522	sequence-specific DNA binding
CTM43_RS26820	COG1956	GAF domain-containing protein
CTM43_RS26825	COG1956	GAF domain-containing protein
CTM43_RS26935	COG0523	cobalamin synthesis protein
CTM43_RS26940	COG0500	methyltransferase
CTM43_RS26955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTM43_RS26965	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CTM43_RS26990	COG0735	belongs to the Fur family
CTM43_RS26995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CTM43_RS27000	COG0523	cobalamin synthesis protein
CTM43_RS27030	COG0523	cobalamin synthesis protein
CTM43_RS27070	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CTM43_RS27120	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CTM43_RS27135	COG0789	Transcriptional regulator
CTM43_RS27140	COG2205	protein histidine kinase activity
CTM43_RS27145	COG0745	RESPONSE REGULATOR receiver
CTM43_RS27150	COG1276	copper resistance
CTM43_RS27155	COG2372	response to copper ion
CTM43_RS27160	COG3667	copper resistance
CTM43_RS27165	COG2132	Multicopper oxidase
CTM43_RS27175	COG0739	heme binding
CTM43_RS27205	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTM43_RS27305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTM43_RS27330	COG0656	L-ascorbic acid biosynthetic process
CTM43_RS27335	COG2916	Histone family protein nucleoid-structuring protein H-NS
CTM43_RS27455	COG5654	RES domain protein
CTM43_RS27460	COG5642	Protein of unknown function (DUF2384)
CTM43_RS27475	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CTM43_RS27480	COG4772	TonB-dependent receptor
CTM43_RS27490	COG1595	DNA-templated transcription, initiation
CTM43_RS27505	COG3969	phosphoadenosine phosphosulfate
CTM43_RS27510	COG1475	DNA binding
CTM43_RS27530	COG2382	esterase
CTM43_RS27565	COG0500	methyltransferase
CTM43_RS27800	COG3504	Conjugal transfer protein
CTM43_RS27850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTM43_RS27860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CTM43_RS27900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs