locus-tag	class	description
CI103_RS00020	COG0187	DNA topoisomerase II activity
CI103_RS00025	COG0561	phosphatase activity
CI103_RS00040	COG2186	Transcriptional regulator
CI103_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
CI103_RS00050	COG0800	Aldolase
CI103_RS00060	COG2271	Major facilitator Superfamily
CI103_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
CI103_RS00070	COG5645	(Lipo)protein
CI103_RS00085	COG3645	SOS response
CI103_RS00095	COG2188	Transcriptional regulator
CI103_RS00110	COG2149	membrane
CI103_RS00130	COG2610	gluconate transmembrane transporter activity
CI103_RS00135	COG0583	DNA-binding transcription factor activity
CI103_RS00140	COG2814	Major facilitator Superfamily
CI103_RS00165	COG0028	Belongs to the TPP enzyme family
CI103_RS00170	COG0440	acetolactate synthase activity
CI103_RS00175	COG2197	response regulator
CI103_RS00185	COG2271	Major facilitator Superfamily
CI103_RS00230	COG2188	Transcriptional regulator
CI103_RS00255	COG4580	involved in the transport of maltose and maltodextrins
CI103_RS00260	COG1447	Phosphotransferase system cellobiose-specific component IIA
CI103_RS00265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI103_RS00265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI103_RS00275	COG1609	Transcriptional regulator
CI103_RS00285	COG3384	dioxygenase
CI103_RS00290	COG0583	DNA-binding transcription factor activity
CI103_RS00295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CI103_RS00300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CI103_RS00305	COG2828	Protein conserved in bacteria
CI103_RS00320	COG0697	spore germination
CI103_RS00325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI103_RS00325	COG1263	PTS System
CI103_RS00335	COG2814	Major facilitator Superfamily
CI103_RS00345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CI103_RS00380	COG0583	DNA-binding transcription factor activity
CI103_RS00405	COG1464	Belongs to the NlpA lipoprotein family
CI103_RS00420	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CI103_RS00430	COG1064	alcohol dehydrogenase
CI103_RS00465	COG2211	Major facilitator Superfamily
CI103_RS00470	COG1501	Belongs to the glycosyl hydrolase 31 family
CI103_RS00480	COG1486	melibiose metabolic process
CI103_RS00485	COG1263	PTS System
CI103_RS00485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI103_RS00490	COG2982	Protein involved in outer membrane biogenesis
CI103_RS00495	COG2233	PERMEase
CI103_RS00500	COG0786	glutamate:sodium symporter activity
CI103_RS00520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CI103_RS00545	COG3152	Membrane
CI103_RS00555	COG1494	fructose-1,6-bisphosphatase
CI103_RS00560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CI103_RS00565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CI103_RS00570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CI103_RS00590	COG2860	membrane
CI103_RS00600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CI103_RS00600	COG2169	Transcriptional regulator
CI103_RS00605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CI103_RS00610	COG1561	YicC-like family, N-terminal region
CI103_RS00630	COG1131	(ABC) transporter
CI103_RS00635	COG0842	Transport permease protein
CI103_RS00660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CI103_RS00695	COG1519	Transferase
CI103_RS00700	COG1216	Glycosyl transferase, family 2
CI103_RS00705	COG0438	transferase activity, transferring glycosyl groups
CI103_RS00715	COG0859	PFAM glycosyl transferase family 9
CI103_RS00740	COG0859	PFAM glycosyl transferase family 9
CI103_RS00755	COG0156	8-amino-7-oxononanoate synthase activity
CI103_RS00765	COG0463	Glycosyl transferase, family 2
CI103_RS00770	COG2861	carbohydrate metabolic process
CI103_RS00775	COG4942	peptidase
CI103_RS00785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CI103_RS00790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CI103_RS00810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CI103_RS00820	COG2186	Transcriptional regulator
CI103_RS00840	COG3722	fumarate hydratase activity
CI103_RS00860	COG1566	PFAM secretion protein HlyD family protein
CI103_RS00865	COG0625	glutathione transferase activity
CI103_RS00875	COG3276	selenocysteine insertion sequence binding
CI103_RS00880	COG1414	Transcriptional regulator
CI103_RS00885	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI103_RS00890	COG3977	Valine--pyruvate aminotransferase
CI103_RS00895	COG0366	Alpha amylase catalytic
CI103_RS00905	COG2992	FlgJ-related protein
CI103_RS00910	COG1609	Transcriptional regulator
CI103_RS00910	COG2207	Transcriptional regulator
CI103_RS00915	COG4214	carbohydrate transport
CI103_RS00925	COG4213	ABC transporter substrate-binding protein
CI103_RS00945	COG4682	membrane
CI103_RS00950	COG4682	membrane
CI103_RS00955	COG3274	enterobacterial common antigen metabolic process
CI103_RS00995	COG1278	Cold shock
CI103_RS01000	COG2944	sequence-specific DNA binding
CI103_RS01005	COG2814	Major facilitator Superfamily
CI103_RS01025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI103_RS01035	COG1609	Transcriptional regulator
CI103_RS01040	COG2885	chlorophyll binding
CI103_RS01045	COG0243	molybdopterin cofactor binding
CI103_RS01050	COG0456	acetyltransferase
CI103_RS01055	COG2818	Glycosylase
CI103_RS01060	COG5571	outer membrane autotransporter
CI103_RS01065	COG2223	nitrite transmembrane transporter activity
CI103_RS01100	COG0747	negative chemotaxis
CI103_RS01105	COG0601	transmembrane transport
CI103_RS01110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CI103_RS01115	COG0444	Belongs to the ABC transporter superfamily
CI103_RS01120	COG4608	Belongs to the ABC transporter superfamily
CI103_RS01145	COG1215	transferase activity, transferring glycosyl groups
CI103_RS01150	COG0457	Tetratricopeptide repeat
CI103_RS01165	COG2194	sulfuric ester hydrolase activity
CI103_RS01195	COG1215	transferase activity, transferring glycosyl groups
CI103_RS01200	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CI103_RS01205	COG0457	Tetratricopeptide repeat
CI103_RS01205	COG3118	belongs to the thioredoxin family
CI103_RS01210	COG2199	diguanylate cyclase activity
CI103_RS01210	COG2200	EAL domain
CI103_RS01220	COG0612	Peptidase, M16
CI103_RS01235	COG2982	Protein involved in outer membrane biogenesis
CI103_RS01240	COG0477	Major facilitator Superfamily
CI103_RS01245	COG1295	ribonuclease BN
CI103_RS01250	COG0583	DNA-binding transcription factor activity
CI103_RS01255	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS01260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CI103_RS01270	COG1454	alcohol dehydrogenase
CI103_RS01280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CI103_RS01285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CI103_RS01290	COG0671	phosphoesterase, PA-phosphatase related
CI103_RS01310	COG0589	response to stress
CI103_RS01320	COG0306	phosphate transporter
CI103_RS01325	COG2081	HI0933 family
CI103_RS01330	COG2239	Acts as a magnesium transporter
CI103_RS01340	COG1124	(ABC) transporter
CI103_RS01350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CI103_RS01355	COG0601	transmembrane transport
CI103_RS01360	COG0747	negative chemotaxis
CI103_RS01370	COG3479	Phenolic acid decarboxylase
CI103_RS01410	COG0628	permease
CI103_RS01415	COG0477	Major facilitator Superfamily
CI103_RS01425	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CI103_RS01440	COG3714	YhhN family
CI103_RS01450	COG3776	membrane
CI103_RS01455	COG0742	ribosomal rna small subunit methyltransferase
CI103_RS01460	COG0552	protein localization to endoplasmic reticulum
CI103_RS01465	COG2884	Cell division ATP-binding protein ftsE
CI103_RS01470	COG2177	Part of the ABC transporter FtsEX involved in
CI103_RS01485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CI103_RS01495	COG0683	leucine binding
CI103_RS01505	COG0683	leucine binding
CI103_RS01510	COG0559	Belongs to the binding-protein-dependent transport system permease family
CI103_RS01560	COG0584	glycerophosphoryl diester phosphodiesterase
CI103_RS01570	COG0405	Gamma-glutamyltransferase
CI103_RS01575	COG1247	-acetyltransferase
CI103_RS01590	COG0673	inositol 2-dehydrogenase activity
CI103_RS01595	COG1741	Belongs to the pirin family
CI103_RS01600	COG1609	Transcriptional regulator
CI103_RS01605	COG3265	gluconokinase activity
CI103_RS01610	COG2610	gluconate transmembrane transporter activity
CI103_RS01620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CI103_RS01645	COG0058	SHG alpha-glucan phosphorylase activity
CI103_RS01660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CI103_RS01675	COG1349	DNA-binding transcription factor activity
CI103_RS01690	COG0058	SHG alpha-glucan phosphorylase activity
CI103_RS01695	COG1640	4-alpha-glucanotransferase
CI103_RS01700	COG2610	gluconate transmembrane transporter activity
CI103_RS01710	COG1040	competence protein
CI103_RS01735	COG1918	ferrous iron import across plasma membrane
CI103_RS01740	COG2183	response to ionizing radiation
CI103_RS01745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CI103_RS01770	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CI103_RS01775	COG1011	Hydrolase
CI103_RS01785	COG0494	nUDIX hydrolase
CI103_RS01790	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CI103_RS01815	COG4796	Type ii and iii secretion system protein
CI103_RS01835	COG3266	domain, Protein
CI103_RS01840	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CI103_RS01845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CI103_RS01870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CI103_RS01875	COG0402	S-adenosylhomocysteine deaminase activity
CI103_RS01880	COG0738	Major facilitator superfamily
CI103_RS01905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CI103_RS01910	COG1289	transmembrane transporter activity
CI103_RS01925	COG1765	OsmC-like protein
CI103_RS01930	COG3954	Phosphoribulokinase
CI103_RS01940	COG0429	hydrolase of the alpha beta-hydrolase fold
CI103_RS01950	COG0488	(ABC) transporter
CI103_RS01965	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CI103_RS01970	COG1047	Peptidyl-prolyl cis-trans
CI103_RS01980	COG0545	Peptidyl-prolyl cis-trans isomerase
CI103_RS01985	COG2964	Protein conserved in bacteria
CI103_RS02040	COG0051	transcription antitermination factor activity, RNA binding
CI103_RS02065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CI103_RS02080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CI103_RS02145	COG0201	protein transport
CI103_RS02170	COG0202	RNA polymerase activity
CI103_RS02185	COG0789	Transcriptional regulator
CI103_RS02190	COG3036	rescue of stalled ribosome
CI103_RS02220	COG0758	DNA mediated transformation
CI103_RS02230	COG0551	DNA topoisomerase type I activity
CI103_RS02250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CI103_RS02285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CI103_RS02290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI103_RS02295	COG1309	transcriptional regulator
CI103_RS02300	COG0582	viral genome integration into host DNA
CI103_RS02315	COG3561	AntA/AntB antirepressor
CI103_RS02405	COG1802	Transcriptional regulator
CI103_RS02405	COG4626	Terminase
CI103_RS02435	COG4145	pantothenate transmembrane transporter activity
CI103_RS02440	COG3924	membrane
CI103_RS02445	COG0439	Biotin carboxylase
CI103_RS02450	COG0511	ligase activity, forming carbon-carbon bonds
CI103_RS02480	COG2199	diguanylate cyclase activity
CI103_RS02480	COG2200	EAL domain
CI103_RS02490	COG1077	Cell shape determining protein MreB Mrl
CI103_RS02495	COG1792	Involved in formation and maintenance of cell shape
CI103_RS02500	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CI103_RS02510	COG1530	ribonuclease E activity
CI103_RS02515	COG3164	Protein of unknown function
CI103_RS02520	COG0312	modulator of DNA gyrase
CI103_RS02525	COG0583	DNA-binding transcription factor activity
CI103_RS02540	COG1289	transmembrane transporter activity
CI103_RS02545	COG2732	(Barnase) inhibitor
CI103_RS02570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CI103_RS02575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CI103_RS02580	COG3105	Protein conserved in bacteria
CI103_RS02585	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CI103_RS02605	COG0625	glutathione transferase activity
CI103_RS02610	COG2969	positive regulation of protein catabolic process
CI103_RS02620	COG0493	'glutamate synthase
CI103_RS02625	COG0070	glutamate synthase
CI103_RS02625	COG0067	glutamate synthase
CI103_RS02625	COG0069	glutamate synthase activity
CI103_RS02635	COG1242	4 iron, 4 sulfur cluster binding
CI103_RS02640	COG2271	Major facilitator Superfamily
CI103_RS02645	COG1063	alcohol dehydrogenase
CI103_RS02650	COG1312	Catalyzes the dehydration of D-mannonate
CI103_RS02655	COG0784	Response regulator, receiver
CI103_RS02655	COG2198	Histidine kinase
CI103_RS02655	COG5002	protein histidine kinase activity
CI103_RS02660	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CI103_RS02665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CI103_RS02670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS02680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS02685	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CI103_RS02690	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CI103_RS02695	COG1137	ATPase activity
CI103_RS02700	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CI103_RS02705	COG3117	lipopolysaccharide transmembrane transporter activity
CI103_RS02710	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CI103_RS02720	COG0530	calcium, potassium:sodium antiporter activity
CI103_RS02730	COG1127	ABC transporter
CI103_RS02735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CI103_RS02740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CI103_RS02745	COG2854	intermembrane phospholipid transfer
CI103_RS02750	COG3113	response to antibiotic
CI103_RS02755	COG5007	Belongs to the BolA IbaG family
CI103_RS02765	COG3423	Transcriptional regulator
CI103_RS02770	COG0142	geranyltranstransferase activity
CI103_RS02785	COG0697	spore germination
CI103_RS02795	COG2027	D-alanyl-D-alanine carboxypeptidase
CI103_RS02805	COG1534	Rna-binding protein
CI103_RS02820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CI103_RS02825	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CI103_RS02835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CI103_RS02875	COG0195	Participates in both transcription termination and antitermination
CI103_RS02925	COG0814	amino acid
CI103_RS02930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CI103_RS02935	COG0826	peptidase U32
CI103_RS02940	COG0826	peptidase U32
CI103_RS02945	COG3154	lipid carrier protein
CI103_RS02950	COG3153	acetyltransferase
CI103_RS02965	COG0693	protein deglycase activity
CI103_RS02970	COG0702	epimerase
CI103_RS02975	COG0701	Predicted permease
CI103_RS02980	COG2823	Periplasmic or secreted lipoprotein
CI103_RS03000	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CI103_RS03015	COG1063	alcohol dehydrogenase
CI103_RS03020	COG3775	system Galactitol-specific IIC component
CI103_RS03025	COG3414	Phosphotransferase system galactitol-specific IIB component
CI103_RS03030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS03040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS03040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS03045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CI103_RS03045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CI103_RS03045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS03050	COG1105	Belongs to the carbohydrate kinase PfkB family
CI103_RS03060	COG1349	DNA-binding transcription factor activity
CI103_RS03065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI103_RS03070	COG2721	sulfolactate sulfo-lyase activity
CI103_RS03075	COG2271	Major facilitator Superfamily
CI103_RS03085	COG2084	Dehydrogenase
CI103_RS03090	COG1929	Belongs to the glycerate kinase type-1 family
CI103_RS03110	COG1741	Belongs to the pirin family
CI103_RS03115	COG0583	DNA-binding transcription factor activity
CI103_RS03120	COG3152	Membrane
CI103_RS03125	COG0435	Glutathione S-transferase
CI103_RS03130	COG2259	Doxx family
CI103_RS03140	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CI103_RS03145	COG4575	ribosome binding
CI103_RS03150	COG1422	Protein of unknown function (DUF1090)
CI103_RS03160	COG0586	Pfam SNARE associated Golgi protein
CI103_RS03165	COG2186	Transcriptional regulator
CI103_RS03170	COG2271	Major facilitator Superfamily
CI103_RS03180	COG2721	sulfolactate sulfo-lyase activity
CI103_RS03195	COG0861	Integral membrane protein TerC family
CI103_RS03200	COG0673	inositol 2-dehydrogenase activity
CI103_RS03205	COG1451	nucleotide metabolic process
CI103_RS03225	COG0446	pyridine nucleotide-disulphide oxidoreductase
CI103_RS03225	COG1902	pentaerythritol trinitrate reductase activity
CI103_RS03280	COG1695	Transcriptional regulator
CI103_RS03285	COG2375	cellular response to nickel ion
CI103_RS03300	COG1461	Dihydroxyacetone kinase
CI103_RS03305	COG2376	Dihydroxyacetone kinase
CI103_RS03385	COG3247	response to pH
CI103_RS03395	COG2205	protein histidine kinase activity
CI103_RS03395	COG0784	Response regulator, receiver
CI103_RS03395	COG2198	Histidine kinase
CI103_RS03395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI103_RS03400	COG2197	response regulator
CI103_RS03425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CI103_RS03430	COG0358	DNA primase activity
CI103_RS03435	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CI103_RS03500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CI103_RS03515	COG4991	sh3 domain protein
CI103_RS03520	COG3025	triphosphatase activity
CI103_RS03540	COG2960	long-chain fatty acid transporting porin activity
CI103_RS03555	COG3384	dioxygenase
CI103_RS03560	COG0754	glutathionylspermidine amidase activity
CI103_RS03575	COG0494	nUDIX hydrolase
CI103_RS03580	COG3151	Protein conserved in bacteria
CI103_RS03585	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CI103_RS03590	COG3150	esterase
CI103_RS03600	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CI103_RS03605	COG2249	NAD(P)H dehydrogenase (quinone) activity
CI103_RS03610	COG0642	Histidine kinase
CI103_RS03620	COG3111	PFAM Bacterial OB fold (BOF) protein
CI103_RS03625	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CI103_RS03630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CI103_RS03635	COG0204	Acyl-transferase
CI103_RS03640	COG2132	Multicopper oxidase
CI103_RS03645	COG1032	radical SAM domain protein
CI103_RS03655	COG0656	L-ascorbic acid biosynthetic process
CI103_RS03660	COG1979	alcohol dehydrogenase
CI103_RS03665	COG2207	Transcriptional regulator
CI103_RS03670	COG0586	Pfam SNARE associated Golgi protein
CI103_RS03675	COG0626	cystathionine gamma-synthase activity
CI103_RS03690	COG0848	biopolymer transport protein
CI103_RS03695	COG2211	Major facilitator Superfamily
CI103_RS03720	COG0625	glutathione transferase activity
CI103_RS03730	COG0754	glutathionylspermidine amidase activity
CI103_RS03735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CI103_RS03755	COG0583	DNA-binding transcription factor activity
CI103_RS03760	COG0626	cystathionine gamma-synthase activity
CI103_RS04025	COG3423	Transcriptional regulator
CI103_RS04035	COG1278	Cold shock
CI103_RS04040	COG3423	Transcriptional regulator
CI103_RS04100	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CI103_RS04110	COG1811	Na channel or pump
CI103_RS04120	COG1982	Orn Lys Arg decarboxylase major
CI103_RS04125	COG2211	Major facilitator Superfamily
CI103_RS04140	COG1194	a g-specific adenine glycosylase
CI103_RS04150	COG3171	Protein conserved in bacteria
CI103_RS04160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CI103_RS04175	COG0762	integral membrane protein
CI103_RS04180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CI103_RS04185	COG2805	Type II/IV secretion system protein
CI103_RS04205	COG0189	ligase activity
CI103_RS04210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CI103_RS04215	COG2356	endonuclease I
CI103_RS04225	COG2814	Major facilitator Superfamily
CI103_RS04270	COG2146	nitrite reductase [NAD(P)H] activity
CI103_RS04285	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS04290	COG1414	Transcriptional regulator
CI103_RS04320	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS04325	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CI103_RS04345	COG0501	Belongs to the peptidase M48B family
CI103_RS04350	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CI103_RS04365	COG0191	fructose-bisphosphate aldolase activity
CI103_RS04370	COG0668	transmembrane transport
CI103_RS04380	COG2968	Membrane
CI103_RS04395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CI103_RS04400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CI103_RS04420	COG0006	proline dipeptidase activity
CI103_RS04425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CI103_RS04430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CI103_RS04450	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS04455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CI103_RS04475	COG2723	6-phospho-beta-galactosidase activity
CI103_RS04480	COG1737	Transcriptional regulator
CI103_RS04490	COG1272	protein, Hemolysin III
CI103_RS04500	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CI103_RS04510	COG0716	FMN binding
CI103_RS04515	COG4974	Belongs to the 'phage' integrase family
CI103_RS04525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CI103_RS04550	COG4942	peptidase
CI103_RS04560	COG2814	Major facilitator Superfamily
CI103_RS04575	COG0667	Aldo Keto reductase
CI103_RS04610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CI103_RS04615	COG1393	Belongs to the ArsC family
CI103_RS04630	COG1538	Outer membrane efflux protein
CI103_RS04635	COG1289	transmembrane transporter activity
CI103_RS04650	COG3592	Divergent 4Fe-4S mono-cluster
CI103_RS04655	COG2388	GCN5-related N-acetyl-transferase
CI103_RS04665	COG3539	Fimbrial protein
CI103_RS04670	COG3539	Fimbrial protein
CI103_RS04675	COG3539	Fimbrial protein
CI103_RS04680	COG3188	usher protein
CI103_RS04685	COG3121	Chaperone
CI103_RS04690	COG3539	Fimbrial protein
CI103_RS04700	COG4974	Belongs to the 'phage' integrase family
CI103_RS04705	COG0582	viral genome integration into host DNA
CI103_RS04715	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CI103_RS04720	COG1846	Transcriptional regulator
CI103_RS04725	COG0697	spore germination
CI103_RS04790	COG0667	Aldo Keto reductase
CI103_RS04795	COG0814	amino acid
CI103_RS04810	COG0183	Belongs to the thiolase family
CI103_RS04820	COG0823	Involved in the tonB-independent uptake of proteins
CI103_RS04825	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS04830	COG2814	Major facilitator Superfamily
CI103_RS04860	COG3842	ATPase activity
CI103_RS04865	COG0395	ABC-type sugar transport system, permease component
CI103_RS04870	COG1175	transmembrane transport
CI103_RS04875	COG1917	Cupin 2, conserved barrel domain protein
CI103_RS04880	COG1794	racemase activity, acting on amino acids and derivatives
CI103_RS04885	COG0583	DNA-binding transcription factor activity
CI103_RS04895	COG1609	Transcriptional regulator
CI103_RS04900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI103_RS04905	COG2723	6-phospho-beta-galactosidase activity
CI103_RS04910	COG2186	Transcriptional regulator
CI103_RS04920	COG1609	Transcriptional regulator
CI103_RS04945	COG0667	Aldo Keto reductase
CI103_RS04955	COG0861	Integral membrane protein TerC family
CI103_RS04985	COG2165	general secretion pathway protein
CI103_RS04990	COG4795	General secretion pathway protein
CI103_RS05000	COG4967	type IV pilus modification protein PilV
CI103_RS05005	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CI103_RS05010	COG1025	Belongs to the peptidase M16 family
CI103_RS05015	COG1074	ATP-dependent DNA helicase activity
CI103_RS05020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CI103_RS05030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CI103_RS05030	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CI103_RS05035	COG0860	N-Acetylmuramoyl-L-alanine amidase
CI103_RS05040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CI103_RS05070	COG4656	Part of a membrane complex involved in electron transport
CI103_RS05075	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS05075	COG1454	alcohol dehydrogenase
CI103_RS05105	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CI103_RS05270	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CI103_RS05275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CI103_RS05280	COG2166	iron-sulfur cluster assembly
CI103_RS05285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CI103_RS05295	COG0583	DNA-binding transcription factor activity
CI103_RS05300	COG2363	Small membrane protein
CI103_RS05310	COG1349	DNA-binding transcription factor activity
CI103_RS05330	COG0738	Major facilitator superfamily
CI103_RS05335	COG0235	Class ii aldolase
CI103_RS05340	COG1454	alcohol dehydrogenase
CI103_RS05355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CI103_RS05370	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CI103_RS05375	COG2011	ABC-type metal ion transport system permease component
CI103_RS05380	COG1464	Belongs to the NlpA lipoprotein family
CI103_RS05390	COG0477	Major facilitator Superfamily
CI103_RS05400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CI103_RS05405	COG1760	l-serine dehydratase
CI103_RS05410	COG0814	amino acid
CI103_RS05415	COG1611	Belongs to the LOG family
CI103_RS05430	COG3098	single-species biofilm formation
CI103_RS05435	COG0564	pseudouridine synthase activity
CI103_RS05440	COG0716	FMN binding
CI103_RS05445	COG2271	Major facilitator Superfamily
CI103_RS05450	COG4948	Mandelate Racemase Muconate Lactonizing
CI103_RS05455	COG4948	Mandelate Racemase Muconate Lactonizing
CI103_RS05460	COG1929	Belongs to the glycerate kinase type-1 family
CI103_RS05465	COG2205	protein histidine kinase activity
CI103_RS05465	COG3437	response regulator, receiver
CI103_RS05465	COG3850	Histidine kinase
CI103_RS05465	COG4999	Histidine kinase
CI103_RS05475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CI103_RS05480	COG3956	TIGRFAM MazG family protein
CI103_RS05500	COG0602	queuosine metabolic process
CI103_RS05505	COG0720	synthase
CI103_RS05525	COG2234	aminopeptidase activity
CI103_RS05585	COG1388	LysM domain
CI103_RS05585	COG4942	peptidase
CI103_RS05590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CI103_RS05615	COG0163	prenyltransferase activity
CI103_RS05620	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CI103_RS05660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI103_RS05665	COG4558	Periplasmic binding protein
CI103_RS05670	COG3720	iron ion transport
CI103_RS05690	COG0679	Auxin Efflux Carrier
CI103_RS05705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CI103_RS05710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CI103_RS05715	COG1121	(ABC) transporter
CI103_RS05720	COG0803	Belongs to the bacterial solute-binding protein 9 family
CI103_RS05725	COG1609	Transcriptional regulator
CI103_RS05730	COG1940	carbohydrate kinase activity
CI103_RS05735	COG1447	Phosphotransferase system cellobiose-specific component IIA
CI103_RS05740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI103_RS05745	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI103_RS05750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI103_RS05755	COG4580	involved in the transport of maltose and maltodextrins
CI103_RS05765	COG2723	6-phospho-beta-galactosidase activity
CI103_RS05775	COG0309	Hydrogenase expression formation protein (HypE)
CI103_RS05780	COG0409	Hydrogenase expression formation protein
CI103_RS05785	COG0298	carbon dioxide binding
CI103_RS05790	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CI103_RS05810	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI103_RS05815	COG0651	ATP synthesis coupled electron transport
CI103_RS05820	COG0650	Formate hydrogenlyase subunit 4
CI103_RS05825	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CI103_RS05825	COG3261	NADH dehydrogenase
CI103_RS05830	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CI103_RS05835	COG3260	NADH ubiquinone oxidoreductase 20
CI103_RS05845	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CI103_RS05855	COG2723	6-phospho-beta-galactosidase activity
CI103_RS05860	COG1263	PTS System
CI103_RS05860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI103_RS05865	COG1609	Transcriptional regulator
CI103_RS05870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI103_RS05875	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CI103_RS05880	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CI103_RS05910	COG1349	DNA-binding transcription factor activity
CI103_RS05915	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS05920	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS05930	COG3732	PTS system glucitol sorbitol-specific
CI103_RS05935	COG3730	PTS system glucitol sorbitol-specific
CI103_RS05940	COG2951	lytic endotransglycosylase activity
CI103_RS05950	COG1121	(ABC) transporter
CI103_RS05955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CI103_RS05960	COG0803	Belongs to the bacterial solute-binding protein 9 family
CI103_RS05965	COG1546	Belongs to the CinA family
CI103_RS05990	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CI103_RS06020	COG2823	Periplasmic or secreted lipoprotein
CI103_RS06025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CI103_RS06030	COG1238	metal cluster binding
CI103_RS06050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CI103_RS06055	COG2814	Major facilitator Superfamily
CI103_RS06060	COG1566	PFAM secretion protein HlyD family protein
CI103_RS06065	COG1846	Transcriptional regulator
CI103_RS06075	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CI103_RS06085	COG4176	ABC-type proline glycine betaine transport system permease component
CI103_RS06100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CI103_RS06110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CI103_RS06115	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CI103_RS06120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CI103_RS06125	COG4575	ribosome binding
CI103_RS06150	COG2916	Histone family protein nucleoid-structuring protein H-NS
CI103_RS06165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CI103_RS06170	COG0640	Transcriptional regulator
CI103_RS06180	COG0583	DNA-binding transcription factor activity
CI103_RS06185	COG3284	Transcriptional regulator
CI103_RS06195	COG3539	Fimbrial protein
CI103_RS06200	COG3121	Chaperone
CI103_RS06220	COG3188	usher protein
CI103_RS06230	COG3539	Fimbrial protein
CI103_RS06235	COG2197	response regulator
CI103_RS06250	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS06260	COG0235	Class ii aldolase
CI103_RS06270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI103_RS06305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI103_RS06310	COG3708	Transcriptional regulator
CI103_RS06310	COG2207	Transcriptional regulator
CI103_RS06340	COG2867	negative regulation of translational initiation
CI103_RS06355	COG0497	DNA recombination
CI103_RS06375	COG4536	flavin adenine dinucleotide binding
CI103_RS06380	COG4137	Cytochrome C assembly protein
CI103_RS06385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CI103_RS06420	COG2885	chlorophyll binding
CI103_RS06425	COG2199	diguanylate cyclase activity
CI103_RS06435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CI103_RS06440	COG1605	Chorismate mutase
CI103_RS06440	COG0287	Prephenate dehydrogenase
CI103_RS06450	COG0077	Prephenate dehydratase
CI103_RS06450	COG1605	Chorismate mutase
CI103_RS06455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CI103_RS06460	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CI103_RS06475	COG0542	response to heat
CI103_RS06500	COG0477	Major facilitator Superfamily
CI103_RS06505	COG5544	Lipoprotein
CI103_RS06510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CI103_RS06520	COG3148	PFAM DTW domain containing protein
CI103_RS06525	COG3118	belongs to the thioredoxin family
CI103_RS06535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CI103_RS06550	COG0513	Belongs to the DEAD box helicase family
CI103_RS06560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CI103_RS06570	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CI103_RS06575	COG3026	antisigma factor binding
CI103_RS06580	COG3086	response to oxidative stress
CI103_RS06590	COG0681	Belongs to the peptidase S26 family
CI103_RS06610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CI103_RS06620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI103_RS06625	COG1737	Transcriptional regulator
CI103_RS06630	COG0560	Phosphoserine phosphatase
CI103_RS06645	COG0047	phosphoribosylformylglycinamidine synthase activity
CI103_RS06645	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CI103_RS06650	COG2205	protein histidine kinase activity
CI103_RS06655	COG3170	Tfp pilus assembly protein FimV
CI103_RS06660	COG2204	response regulator
CI103_RS06665	COG0347	Belongs to the P(II) protein family
CI103_RS06670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CI103_RS06670	COG1017	nitric oxide dioxygenase activity
CI103_RS06685	COG2259	Doxx family
CI103_RS06690	COG1940	carbohydrate kinase activity
CI103_RS06695	COG0457	Tetratricopeptide repeat
CI103_RS06700	COG2814	Major facilitator Superfamily
CI103_RS06700	COG0477	Major facilitator Superfamily
CI103_RS06705	COG2017	converts alpha-aldose to the beta-anomer
CI103_RS06710	COG2814	Major facilitator Superfamily
CI103_RS06715	COG3711	transcriptional antiterminator
CI103_RS06720	COG3683	transport system, periplasmic component
CI103_RS06725	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CI103_RS06755	COG0822	iron-sulfur transferase activity
CI103_RS06775	COG0633	Ferredoxin
CI103_RS06780	COG2975	iron-sulfur cluster assembly
CI103_RS06800	COG2897	thiosulfate sulfurtransferase activity
CI103_RS06805	COG2373	Large extracellular alpha-helical protein
CI103_RS06810	COG4953	penicillin-binding protein 1C
CI103_RS06840	COG2976	Protein conserved in bacteria
CI103_RS06860	COG1645	bacterial-type flagellum-dependent swarming motility
CI103_RS06870	COG0517	IMP dehydrogenase activity
CI103_RS06870	COG0516	GMP reductase activity
CI103_RS06920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CI103_RS07010	COG5484	DNA packaging
CI103_RS07010	COG3728	DNA packaging
CI103_RS07125	COG3617	BRO family, N-terminal domain
CI103_RS07145	COG3344	reverse transcriptase
CI103_RS07170	COG3179	chitinase
CI103_RS07180	COG3119	arylsulfatase activity
CI103_RS07185	COG0641	radical SAM
CI103_RS07205	COG2200	EAL domain
CI103_RS07220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CI103_RS07235	COG2723	6-phospho-beta-galactosidase activity
CI103_RS07245	COG2233	PERMEase
CI103_RS07260	COG1393	Belongs to the ArsC family
CI103_RS07265	COG4783	chaperone-mediated protein folding
CI103_RS07270	COG0628	permease
CI103_RS07275	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CI103_RS07280	COG2716	regulation of RNA biosynthetic process
CI103_RS07290	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CI103_RS07300	COG2321	neutral zinc metallopeptidase
CI103_RS07305	COG1444	tRNA N-acetyltransferase activity
CI103_RS07310	COG0400	carboxylic ester hydrolase activity
CI103_RS07325	COG1393	Belongs to the ArsC family
CI103_RS07330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CI103_RS07340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CI103_RS07340	COG0493	'glutamate synthase
CI103_RS07350	COG5342	invasion associated locus B
CI103_RS07355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CI103_RS07360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CI103_RS07370	COG4810	utilization protein
CI103_RS07460	COG0860	N-Acetylmuramoyl-L-alanine amidase
CI103_RS07480	COG2837	iron assimilation
CI103_RS07490	COG4150	thiosulfate binding
CI103_RS07495	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CI103_RS07500	COG4208	sulfate ABC transporter
CI103_RS07505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CI103_RS07515	COG4319	ketosteroid isomerase
CI103_RS07550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CI103_RS07570	COG3530	Putative quorum-sensing-regulated virulence factor
CI103_RS07575	COG0385	Bile acid
CI103_RS07580	COG0583	DNA-binding transcription factor activity
CI103_RS07610	COG3415	Transposase
CI103_RS07615	COG3415	Transposase
CI103_RS07630	COG2200	EAL domain
CI103_RS07630	COG2199	diguanylate cyclase activity
CI103_RS07635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CI103_RS07650	COG0667	Aldo Keto reductase
CI103_RS07655	COG3961	Belongs to the TPP enzyme family
CI103_RS07670	COG3279	Response regulator of the LytR AlgR family
CI103_RS07675	COG3275	phosphorelay sensor kinase activity
CI103_RS07685	COG0436	Aminotransferase
CI103_RS07690	COG2807	transmembrane transport
CI103_RS07695	COG0590	tRNA wobble adenosine to inosine editing
CI103_RS07700	COG0583	DNA-binding transcription factor activity
CI103_RS07720	COG2116	formate transmembrane transporter activity
CI103_RS07725	COG2853	Lipoprotein
CI103_RS07735	COG3691	Protein conserved in bacteria
CI103_RS07750	COG2062	phosphohistidine phosphatase, SixA
CI103_RS07775	COG0730	response to heat
CI103_RS07780	COG3101	peptidyl-lysine hydroxylation
CI103_RS07795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CI103_RS07815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CI103_RS07825	COG0586	Pfam SNARE associated Golgi protein
CI103_RS07835	COG0285	dihydrofolate synthase activity
CI103_RS07840	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CI103_RS07845	COG1286	toxin biosynthetic process
CI103_RS07850	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CI103_RS07855	COG0163	prenyltransferase activity
CI103_RS07875	COG4160	amino acid transport
CI103_RS07880	COG4598	ABC transporter
CI103_RS07890	COG1090	epimerase
CI103_RS07895	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CI103_RS07900	COG0625	glutathione transferase activity
CI103_RS07905	COG0625	glutathione transferase activity
CI103_RS07910	COG0622	Phosphoesterase
CI103_RS07915	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CI103_RS07920	COG0857	belongs to the CobB CobQ family
CI103_RS07920	COG0280	phosphate acetyltransferase
CI103_RS07940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CI103_RS07945	COG0490	domain, Protein
CI103_RS07945	COG0471	metal ion transport
CI103_RS07955	COG0436	Aminotransferase
CI103_RS07960	COG0583	DNA-binding transcription factor activity
CI103_RS08010	COG0839	Belongs to the complex I subunit 6 family
CI103_RS08020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CI103_RS08025	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CI103_RS08040	COG2153	protein acetylation
CI103_RS08045	COG1169	isochorismate synthase
CI103_RS08070	COG0318	PFAM AMP-dependent synthetase and ligase
CI103_RS08080	COG5464	transposase or invertase
CI103_RS08095	COG1414	Transcriptional regulator
CI103_RS08105	COG2271	Major facilitator Superfamily
CI103_RS08115	COG0247	lactate metabolic process
CI103_RS08125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CI103_RS08130	COG2271	Major facilitator Superfamily
CI103_RS08135	COG0584	glycerophosphoryl diester phosphodiesterase
CI103_RS08145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CI103_RS08175	COG2205	protein histidine kinase activity
CI103_RS08175	COG0784	Response regulator, receiver
CI103_RS08185	COG2198	Histidine kinase
CI103_RS08185	COG0642	Histidine kinase
CI103_RS08200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CI103_RS08200	COG2169	Transcriptional regulator
CI103_RS08205	COG3145	DNA-N1-methyladenine dioxygenase activity
CI103_RS08210	COG4615	Cyclic peptide transporter
CI103_RS08215	COG2239	Acts as a magnesium transporter
CI103_RS08220	COG0659	secondary active sulfate transmembrane transporter activity
CI103_RS08235	COG0628	permease
CI103_RS08260	COG1349	DNA-binding transcription factor activity
CI103_RS08265	COG0494	nUDIX hydrolase
CI103_RS08285	COG1061	Type III restriction enzyme res subunit
CI103_RS08290	COG1187	pseudouridine synthase activity
CI103_RS08295	COG2814	Major facilitator Superfamily
CI103_RS08305	COG4172	Belongs to the ABC transporter superfamily
CI103_RS08310	COG4239	(ABC) transporter, permease
CI103_RS08315	COG4174	ABC transporter (Permease)
CI103_RS08320	COG4166	transmembrane transport
CI103_RS08325	COG2200	EAL domain
CI103_RS08330	COG0791	NLP P60 protein
CI103_RS08335	COG0671	phosphoesterase, PA-phosphatase related
CI103_RS08340	COG0523	cobalamin synthesis protein
CI103_RS08345	COG0246	Mannitol dehydrogenase
CI103_RS08350	COG1312	Catalyzes the dehydration of D-mannonate
CI103_RS08380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS08380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS08385	COG1105	Belongs to the carbohydrate kinase PfkB family
CI103_RS08390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CI103_RS08390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CI103_RS08390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CI103_RS08400	COG2855	membrane
CI103_RS08410	COG0583	DNA-binding transcription factor activity
CI103_RS08415	COG0833	amino acid
CI103_RS08425	COG4771	TonB-dependent receptor
CI103_RS08440	COG2311	Membrane
CI103_RS08455	COG1129	ABC transporter
CI103_RS08465	COG2949	membrane
CI103_RS08475	COG1346	cytolysis
CI103_RS08485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CI103_RS08490	COG3659	wide pore channel activity
CI103_RS08505	COG2723	6-phospho-beta-galactosidase activity
CI103_RS08510	COG1538	Outer membrane efflux protein
CI103_RS08515	COG0586	Pfam SNARE associated Golgi protein
CI103_RS08525	COG1686	Belongs to the peptidase S11 family
CI103_RS08535	COG0277	FAD linked oxidase domain protein
CI103_RS08540	COG1472	Belongs to the glycosyl hydrolase 3 family
CI103_RS08545	COG1732	Glycine betaine
CI103_RS08550	COG1174	glycine betaine transport
CI103_RS08555	COG1125	glycine betaine transport
CI103_RS08560	COG1174	glycine betaine transport
CI103_RS08570	COG3275	phosphorelay sensor kinase activity
CI103_RS08580	COG4807	Protein conserved in bacteria
CI103_RS08600	COG5455	response to cobalt ion
CI103_RS08605	COG0583	DNA-binding transcription factor activity
CI103_RS08610	COG2252	PERMEase
CI103_RS08620	COG0583	DNA-binding transcription factor activity
CI103_RS08635	COG0351	phosphomethylpyrimidine kinase
CI103_RS08640	COG1830	Aldolase
CI103_RS08650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CI103_RS08675	COG1070	Carbohydrate kinase
CI103_RS08685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CI103_RS08690	COG4948	Mandelate Racemase Muconate Lactonizing
CI103_RS08695	COG0747	negative chemotaxis
CI103_RS08700	COG0601	transmembrane transport
CI103_RS08705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CI103_RS08710	COG0444	Belongs to the ABC transporter superfamily
CI103_RS08715	COG4608	Belongs to the ABC transporter superfamily
CI103_RS08725	COG0826	peptidase U32
CI103_RS08730	COG0745	RESPONSE REGULATOR receiver
CI103_RS08735	COG2205	protein histidine kinase activity
CI103_RS08760	COG1301	dicarboxylic acid transport
CI103_RS08775	COG5002	protein histidine kinase activity
CI103_RS08780	COG0443	Heat shock 70 kDa protein
CI103_RS08785	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CI103_RS08800	COG2982	Protein involved in outer membrane biogenesis
CI103_RS08805	COG1253	flavin adenine dinucleotide binding
CI103_RS08830	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CI103_RS08850	COG1215	transferase activity, transferring glycosyl groups
CI103_RS08890	COG2244	polysaccharide biosynthetic process
CI103_RS08895	COG1442	glycosyl transferase family 8
CI103_RS08895	COG1216	Glycosyl transferase, family 2
CI103_RS08955	COG0438	transferase activity, transferring glycosyl groups
CI103_RS08960	COG1216	Glycosyl transferase, family 2
CI103_RS08960	COG1442	glycosyl transferase family 8
CI103_RS08970	COG0463	Glycosyl transferase, family 2
CI103_RS08995	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CI103_RS09020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CI103_RS09025	COG0583	DNA-binding transcription factor activity
CI103_RS09030	COG0531	amino acid
CI103_RS09035	COG0640	Transcriptional regulator
CI103_RS09040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CI103_RS09050	COG2925	Exonuclease
CI103_RS09065	COG3344	reverse transcriptase
CI103_RS09080	COG1289	transmembrane transporter activity
CI103_RS09100	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CI103_RS09110	COG1942	4-Oxalocrotonate Tautomerase
CI103_RS09115	COG0583	DNA-binding transcription factor activity
CI103_RS09120	COG0095	Lipoate-protein ligase
CI103_RS09125	COG0477	Major facilitator Superfamily
CI103_RS09140	COG5001	Diguanylate cyclase
CI103_RS09140	COG3300	MHYT domain
CI103_RS09150	COG3615	Tellurite resistance protein tehB
CI103_RS09175	COG3706	GGDEF domain
CI103_RS09220	COG2916	Histone family protein nucleoid-structuring protein H-NS
CI103_RS09330	COG0582	viral genome integration into host DNA
CI103_RS09340	COG0534	Mate efflux family protein
CI103_RS09350	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CI103_RS09370	COG0604	alcohol dehydrogenase
CI103_RS09375	COG1309	transcriptional regulator
CI103_RS09380	COG0025	NhaP-type Na H and K H
CI103_RS09415	COG0251	oxidation-reduction process
CI103_RS09480	COG4227	nucleotidyltransferase activity
CI103_RS09530	COG3504	Conjugal transfer protein
CI103_RS09605	COG4771	TonB-dependent receptor
CI103_RS09610	COG1021	2,3-dihydroxybenzoate-AMP ligase
CI103_RS09630	COG3433	isochorismatase activity
CI103_RS09630	COG2226	methyltransferase
CI103_RS09630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CI103_RS09645	COG1132	(ABC) transporter
CI103_RS09650	COG2814	Major facilitator Superfamily
CI103_RS09655	COG1169	isochorismate synthase
CI103_RS09660	COG0582	viral genome integration into host DNA
CI103_RS09680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CI103_RS09690	COG1418	mRNA catabolic process
CI103_RS09695	COG0270	DNA (cytosine-5-)-methyltransferase activity
CI103_RS09700	COG3727	T/G mismatch-specific endonuclease activity
CI103_RS09705	COG0697	spore germination
CI103_RS09710	COG2354	Protein conserved in bacteria
CI103_RS09740	COG0366	Alpha amylase catalytic
CI103_RS09745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI103_RS09755	COG0765	amino acid transport
CI103_RS09760	COG1126	abc transporter atp-binding protein
CI103_RS09765	COG2197	response regulator
CI103_RS09775	COG2197	response regulator
CI103_RS09810	COG3012	SEC-C Motif Domain Protein
CI103_RS09810	COG3318	Belongs to the UPF0149 family
CI103_RS09815	COG0814	amino acid
CI103_RS09825	COG1528	Iron-storage protein
CI103_RS09840	COG0477	Major facilitator Superfamily
CI103_RS09850	COG2211	Major facilitator Superfamily
CI103_RS09860	COG1528	Iron-storage protein
CI103_RS09870	COG1879	ABC-type sugar transport system periplasmic component
CI103_RS09880	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS09905	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CI103_RS09915	COG3102	Protein conserved in bacteria
CI103_RS09935	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CI103_RS09940	COG1801	Protein of unknown function DUF72
CI103_RS09945	COG1335	isochorismatase
CI103_RS09955	COG0494	nUDIX hydrolase
CI103_RS09980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CI103_RS09990	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CI103_RS09995	COG0739	heme binding
CI103_RS10000	COG1560	Kdo2-lipid A biosynthetic process
CI103_RS10010	COG1737	Transcriptional regulator
CI103_RS10025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CI103_RS10030	COG0129	dihydroxy-acid dehydratase activity
CI103_RS10035	COG0800	Aldolase
CI103_RS10045	COG3141	response to X-ray
CI103_RS10050	COG2979	Protein of unknown function (DUF533)
CI103_RS10055	COG1770	oligopeptidase
CI103_RS10060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CI103_RS10070	COG2372	response to copper ion
CI103_RS10075	COG1276	copper resistance
CI103_RS10090	COG2990	Protein conserved in bacteria
CI103_RS10115	COG3008	intermembrane lipid transfer
CI103_RS10120	COG2995	paraquat-inducible protein a
CI103_RS10125	COG1956	GAF domain-containing protein
CI103_RS10145	COG2814	Major facilitator Superfamily
CI103_RS10150	COG1414	Transcriptional regulator
CI103_RS10190	COG0768	penicillin binding
CI103_RS10195	COG2226	methyltransferase
CI103_RS10215	COG3716	PTS system mannose fructose sorbose family IID component
CI103_RS10220	COG3715	PTS system
CI103_RS10225	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS10225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI103_RS10230	COG1253	flavin adenine dinucleotide binding
CI103_RS10235	COG2200	EAL domain
CI103_RS10240	COG1760	l-serine dehydratase
CI103_RS10260	COG0251	oxidation-reduction process
CI103_RS10265	COG1199	ATP-dependent helicase activity
CI103_RS10275	COG3065	identical protein binding
CI103_RS10285	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CI103_RS10295	COG2894	cell division
CI103_RS10310	COG0179	Fumarylacetoacetate (FAA) hydrolase
CI103_RS10340	COG2719	SpoVR family
CI103_RS10360	COG1619	proteins homologs of microcin C7 resistance protein MccF
CI103_RS10370	COG4774	siderophore transport
CI103_RS10380	COG2308	Evidence 4 Homologs of previously reported genes of
CI103_RS10420	COG0583	DNA-binding transcription factor activity
CI103_RS10425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CI103_RS10440	COG1882	Formate acetyltransferase
CI103_RS10470	COG0583	DNA-binding transcription factor activity
CI103_RS10500	COG0583	DNA-binding transcription factor activity
CI103_RS10515	COG3122	Protein conserved in bacteria
CI103_RS10545	COG2885	chlorophyll binding
CI103_RS10620	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CI103_RS10710	COG0012	GTP binding
CI103_RS10730	COG0659	secondary active sulfate transmembrane transporter activity
CI103_RS10765	COG2890	protein-(glutamine-N5) methyltransferase activity
CI103_RS10785	COG0387	Pfam Sodium calcium exchanger
CI103_RS10790	COG4572	Cation transport regulator
CI103_RS10795	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CI103_RS10805	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CI103_RS10810	COG3707	response regulator
CI103_RS10815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CI103_RS10825	COG1116	anion transmembrane transporter activity
CI103_RS10830	COG2146	nitrite reductase [NAD(P)H] activity
CI103_RS10830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CI103_RS10835	COG0243	molybdopterin cofactor binding
CI103_RS10840	COG4932	domain protein
CI103_RS10845	COG2197	response regulator
CI103_RS10850	COG3850	Histidine kinase
CI103_RS10855	COG2223	nitrite transmembrane transporter activity
CI103_RS10860	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CI103_RS10865	COG1140	nitrate reductase beta subunit
CI103_RS10870	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CI103_RS10875	COG2181	nitrate reductase activity
CI103_RS10885	COG1522	sequence-specific DNA binding
CI103_RS10920	COG0788	formyltetrahydrofolate deformylase activity
CI103_RS10930	COG1752	Esterase of the alpha-beta hydrolase superfamily
CI103_RS10935	COG0745	RESPONSE REGULATOR receiver
CI103_RS10940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CI103_RS10945	COG2916	Histone family protein nucleoid-structuring protein H-NS
CI103_RS10950	COG1435	thymidine kinase activity
CI103_RS10955	COG1454	alcohol dehydrogenase
CI103_RS10955	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS10965	COG2095	MarC family integral membrane protein
CI103_RS10970	COG4166	transmembrane transport
CI103_RS10975	COG0601	transmembrane transport
CI103_RS10980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CI103_RS10985	COG0444	Belongs to the ABC transporter superfamily
CI103_RS10995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CI103_RS11015	COG2353	YceI-like domain
CI103_RS11020	COG2350	Protein conserved in bacteria
CI103_RS11030	COG3001	Fructosamine kinase
CI103_RS11040	COG1105	Belongs to the carbohydrate kinase PfkB family
CI103_RS11045	COG3137	Salt-induced outer membrane protein
CI103_RS11085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CI103_RS11085	COG0072	phenylalanine-tRNA ligase activity
CI103_RS11105	COG0583	DNA-binding transcription factor activity
CI103_RS11125	COG0386	Belongs to the glutathione peroxidase family
CI103_RS11135	COG0791	NLP P60 protein
CI103_RS11145	COG4256	Hemin uptake protein
CI103_RS11150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CI103_RS11165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CI103_RS11165	COG0574	Belongs to the PEP-utilizing enzyme family
CI103_RS11175	COG0628	permease
CI103_RS11180	COG0277	FAD linked oxidase domain protein
CI103_RS11180	COG0247	lactate metabolic process
CI103_RS11185	COG2050	protein possibly involved in aromatic compounds catabolism
CI103_RS11190	COG2261	transglycosylase associated protein
CI103_RS11225	COG1120	ATPase activity
CI103_RS11230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI103_RS11240	COG0583	DNA-binding transcription factor activity
CI103_RS11265	COG1304	FMN binding
CI103_RS11270	COG1309	transcriptional regulator
CI103_RS11285	COG0316	Belongs to the HesB IscA family
CI103_RS11290	COG0719	Fe-S assembly protein
CI103_RS11295	COG0396	ATPase activity
CI103_RS11300	COG0719	Fe-S assembly protein
CI103_RS11315	COG1376	ErfK ybiS ycfS ynhG family protein
CI103_RS11340	COG1309	transcriptional regulator
CI103_RS11345	COG1082	Xylose isomerase domain protein TIM barrel
CI103_RS11345	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CI103_RS11350	COG2271	Major facilitator Superfamily
CI103_RS11355	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CI103_RS11365	COG1120	ATPase activity
CI103_RS11370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI103_RS11375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CI103_RS11380	COG1414	Transcriptional regulator
CI103_RS11415	COG2814	Major facilitator Superfamily
CI103_RS11435	COG0583	DNA-binding transcription factor activity
CI103_RS11440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CI103_RS11460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CI103_RS11465	COG1116	anion transmembrane transporter activity
CI103_RS11470	COG4774	siderophore transport
CI103_RS11475	COG1120	ATPase activity
CI103_RS11480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI103_RS11485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI103_RS11505	COG0765	amino acid transport
CI103_RS11510	COG1126	abc transporter atp-binding protein
CI103_RS11540	COG1473	amidohydrolase
CI103_RS11545	COG3383	formate dehydrogenase (NAD+) activity
CI103_RS11550	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CI103_RS11565	COG1175	transmembrane transport
CI103_RS11595	COG4133	protoheme IX ABC transporter activity
CI103_RS11600	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CI103_RS11605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CI103_RS11620	COG1138	Cytochrome C-type biogenesis protein
CI103_RS11625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CI103_RS11630	COG3088	subunit of a heme lyase
CI103_RS11630	COG4235	cytochrome complex assembly
CI103_RS11655	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CI103_RS11670	COG5002	protein histidine kinase activity
CI103_RS11670	COG3850	Histidine kinase
CI103_RS11675	COG0745	RESPONSE REGULATOR receiver
CI103_RS11695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CI103_RS11730	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS11735	COG2610	gluconate transmembrane transporter activity
CI103_RS11740	COG1250	3-hydroxyacyl-CoA dehydrogenase
CI103_RS11750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CI103_RS11760	COG0583	DNA-binding transcription factor activity
CI103_RS11785	COG0277	FAD linked oxidase domain protein
CI103_RS11790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CI103_RS11815	COG0402	S-adenosylhomocysteine deaminase activity
CI103_RS11875	COG4608	Belongs to the ABC transporter superfamily
CI103_RS11880	COG0444	Belongs to the ABC transporter superfamily
CI103_RS11905	COG0346	lactoylglutathione lyase activity
CI103_RS11910	COG1349	DNA-binding transcription factor activity
CI103_RS11940	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CI103_RS11995	COG0307	riboflavin synthase, alpha
CI103_RS12000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CI103_RS12005	COG2814	Major facilitator Superfamily
CI103_RS12010	COG0583	DNA-binding transcription factor activity
CI103_RS12025	COG2814	Major facilitator Superfamily
CI103_RS12040	COG0791	NLP P60 protein
CI103_RS12045	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CI103_RS12055	COG0346	lactoylglutathione lyase activity
CI103_RS12060	COG1902	pentaerythritol trinitrate reductase activity
CI103_RS12065	COG1309	transcriptional regulator
CI103_RS12070	COG3313	Fe-S protein
CI103_RS12075	COG4989	oxidoreductase activity
CI103_RS12080	COG2032	superoxide dismutase activity
CI103_RS12085	COG1289	transmembrane transporter activity
CI103_RS12090	COG1566	PFAM secretion protein HlyD family protein
CI103_RS12105	COG3706	GGDEF domain
CI103_RS12120	COG3895	Periplasmic Protein
CI103_RS12135	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CI103_RS12140	COG0625	glutathione transferase activity
CI103_RS12155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CI103_RS12165	COG4659	FMN binding
CI103_RS12200	COG2723	6-phospho-beta-galactosidase activity
CI103_RS12210	COG0673	inositol 2-dehydrogenase activity
CI103_RS12220	COG2814	Major facilitator Superfamily
CI103_RS12240	COG3038	cytochrome b561
CI103_RS12260	COG0583	DNA-binding transcription factor activity
CI103_RS12265	COG3485	protocatechuate 3,4-dioxygenase
CI103_RS12270	COG3485	protocatechuate 3,4-dioxygenase
CI103_RS12275	COG5383	Protein conserved in bacteria
CI103_RS12280	COG2272	Belongs to the type-B carboxylesterase lipase family
CI103_RS12295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CI103_RS12300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CI103_RS12305	COG1275	C4-dicarboxylate transporter malic acid transport protein
CI103_RS12310	COG0500	methyltransferase
CI103_RS12325	COG2207	Transcriptional regulator
CI103_RS12325	COG3708	Transcriptional regulator
CI103_RS12330	COG3135	benzoate transporter
CI103_RS12335	COG1396	sequence-specific DNA binding
CI103_RS12345	COG0826	peptidase U32
CI103_RS12365	COG1294	oxidase, subunit
CI103_RS12370	COG1271	oxidase subunit
CI103_RS12375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CI103_RS12380	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CI103_RS12385	COG3842	ATPase activity
CI103_RS12390	COG1176	ABC-type spermidine putrescine transport system, permease component I
CI103_RS12395	COG1177	transmembrane transport
CI103_RS12400	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS12435	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS12440	COG0747	negative chemotaxis
CI103_RS12450	COG3238	Protein conserved in bacteria
CI103_RS12455	COG1247	-acetyltransferase
CI103_RS12465	COG2130	NADP-dependent
CI103_RS12480	COG3691	Protein conserved in bacteria
CI103_RS12485	COG1228	amidohydrolase
CI103_RS12490	COG4772	TonB-dependent receptor
CI103_RS12515	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CI103_RS12520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CI103_RS12525	COG1473	amidohydrolase
CI103_RS12530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CI103_RS12535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI103_RS12545	COG0765	amino acid transport
CI103_RS12550	COG1126	abc transporter atp-binding protein
CI103_RS12560	COG0625	glutathione transferase activity
CI103_RS12575	COG2211	Major facilitator Superfamily
CI103_RS12590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CI103_RS12595	COG3842	ATPase activity
CI103_RS12600	COG1840	ABC-type Fe3 transport system, periplasmic component
CI103_RS12605	COG1178	ABC-type Fe3 transport system permease component
CI103_RS12610	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CI103_RS12615	COG2181	nitrate reductase activity
CI103_RS12620	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CI103_RS12625	COG1140	nitrate reductase beta subunit
CI103_RS12630	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CI103_RS12650	COG1414	Transcriptional regulator
CI103_RS12655	COG4948	Mandelate Racemase Muconate Lactonizing
CI103_RS12660	COG4829	muconolactone delta-isomerase
CI103_RS12665	COG3485	protocatechuate 3,4-dioxygenase
CI103_RS12675	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CI103_RS12695	COG3383	formate dehydrogenase (NAD+) activity
CI103_RS12695	COG0243	molybdopterin cofactor binding
CI103_RS12700	COG0243	molybdopterin cofactor binding
CI103_RS12700	COG3383	formate dehydrogenase (NAD+) activity
CI103_RS12705	COG0437	4 iron, 4 sulfur cluster binding
CI103_RS12710	COG2864	formate dehydrogenase
CI103_RS12725	COG2326	polyphosphate kinase activity
CI103_RS12735	COG2814	Major facilitator Superfamily
CI103_RS12745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CI103_RS12755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CI103_RS12765	COG0747	negative chemotaxis
CI103_RS12770	COG1064	alcohol dehydrogenase
CI103_RS12785	COG0488	(ABC) transporter
CI103_RS12830	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS12845	COG3111	PFAM Bacterial OB fold (BOF) protein
CI103_RS12855	COG1764	response to oxidative stress
CI103_RS12880	COG3781	membrane
CI103_RS12885	COG0243	molybdopterin cofactor binding
CI103_RS12890	COG0583	DNA-binding transcription factor activity
CI103_RS12895	COG2814	Major facilitator Superfamily
CI103_RS12905	COG1285	pathogenesis
CI103_RS12910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CI103_RS12920	COG0583	DNA-binding transcription factor activity
CI103_RS12940	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CI103_RS12940	COG0519	Catalyzes the synthesis of GMP from XMP
CI103_RS12980	COG0596	Alpha beta hydrolase
CI103_RS12990	COG2205	protein histidine kinase activity
CI103_RS13005	COG0076	glutamate decarboxylase activity
CI103_RS13010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CI103_RS13015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CI103_RS13020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CI103_RS13025	COG1116	anion transmembrane transporter activity
CI103_RS13030	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CI103_RS13040	COG0673	inositol 2-dehydrogenase activity
CI103_RS13055	COG3706	GGDEF domain
CI103_RS13060	COG0402	S-adenosylhomocysteine deaminase activity
CI103_RS13065	COG1953	Uracil, thiamine, allantoin
CI103_RS13105	COG0406	alpha-ribazole phosphatase activity
CI103_RS13125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CI103_RS13140	COG2207	Transcriptional regulator
CI103_RS13155	COG0583	DNA-binding transcription factor activity
CI103_RS13170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CI103_RS13190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CI103_RS13235	COG0765	amino acid transport
CI103_RS13245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CI103_RS13255	COG2070	2-Nitropropane dioxygenase
CI103_RS13260	COG0583	DNA-binding transcription factor activity
CI103_RS13270	COG1902	pentaerythritol trinitrate reductase activity
CI103_RS13275	COG4529	Protein conserved in bacteria
CI103_RS13280	COG0477	Major facilitator Superfamily
CI103_RS13310	COG2223	nitrite transmembrane transporter activity
CI103_RS13320	COG1609	Transcriptional regulator
CI103_RS13325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS13335	COG3037	sugar-specific permease SgaT UlaA
CI103_RS13340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CI103_RS13355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CI103_RS13360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CI103_RS13360	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CI103_RS13360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CI103_RS13375	COG0583	DNA-binding transcription factor activity
CI103_RS13380	COG0583	DNA-binding transcription factor activity
CI103_RS13385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CI103_RS13395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CI103_RS13410	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS13420	COG1609	Transcriptional regulator
CI103_RS13450	COG1652	LysM domain
CI103_RS13480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CI103_RS13480	COG0456	acetyltransferase
CI103_RS13490	COG0667	Aldo Keto reductase
CI103_RS13495	COG0667	Aldo Keto reductase
CI103_RS13500	COG3386	PFAM SMP-30 Gluconolaconase
CI103_RS13505	COG0667	Aldo Keto reductase
CI103_RS13530	COG4977	sequence-specific DNA binding
CI103_RS13550	COG4977	sequence-specific DNA binding
CI103_RS13555	COG1349	DNA-binding transcription factor activity
CI103_RS13570	COG1349	DNA-binding transcription factor activity
CI103_RS13575	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CI103_RS13580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI103_RS13585	COG0738	Major facilitator superfamily
CI103_RS13630	COG1929	Belongs to the glycerate kinase type-1 family
CI103_RS13635	COG3835	regulator
CI103_RS13655	COG2186	Transcriptional regulator
CI103_RS13660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI103_RS13660	COG1263	PTS System
CI103_RS13670	COG2814	Major facilitator Superfamily
CI103_RS13675	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS13675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS13685	COG2819	hydrolase of the alpha beta superfamily
CI103_RS13690	COG5001	Diguanylate cyclase
CI103_RS13690	COG3300	MHYT domain
CI103_RS13725	COG3188	usher protein
CI103_RS13740	COG1649	PFAM Uncharacterised BCR, COG1649
CI103_RS13745	COG3550	peptidyl-serine autophosphorylation
CI103_RS13750	COG1396	sequence-specific DNA binding
CI103_RS13755	COG2351	hydroxyisourate hydrolase activity
CI103_RS13760	COG3195	allantoin biosynthetic process
CI103_RS13760	COG3648	Uricase
CI103_RS13765	COG2233	PERMEase
CI103_RS13795	COG2207	Transcriptional regulator
CI103_RS13810	COG4628	conserved protein (DUF2132)
CI103_RS13830	COG2011	ABC-type metal ion transport system permease component
CI103_RS13835	COG2070	2-Nitropropane dioxygenase
CI103_RS13845	COG0477	Major facilitator Superfamily
CI103_RS13925	COG2199	diguanylate cyclase activity
CI103_RS13940	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS13945	COG0583	DNA-binding transcription factor activity
CI103_RS13955	COG0039	L-malate dehydrogenase activity
CI103_RS13960	COG1349	DNA-binding transcription factor activity
CI103_RS13965	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CI103_RS13970	COG3395	kinase activity
CI103_RS13980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CI103_RS13995	COG2731	YhcH YjgK YiaL family protein
CI103_RS14000	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS14025	COG4977	sequence-specific DNA binding
CI103_RS14035	COG0697	spore germination
CI103_RS14040	COG2814	Major facilitator Superfamily
CI103_RS14050	COG0410	ABC transporter
CI103_RS14055	COG1129	ABC transporter
CI103_RS14070	COG0683	leucine binding
CI103_RS14075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CI103_RS14110	COG2223	nitrite transmembrane transporter activity
CI103_RS14115	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CI103_RS14130	COG1349	DNA-binding transcription factor activity
CI103_RS14135	COG2084	Dehydrogenase
CI103_RS14140	COG3395	kinase activity
CI103_RS14145	COG0235	Class ii aldolase
CI103_RS14150	COG3622	Belongs to the hyi family
CI103_RS14155	COG2610	gluconate transmembrane transporter activity
CI103_RS14160	COG3708	Transcriptional regulator
CI103_RS14160	COG2207	Transcriptional regulator
CI103_RS14185	COG2200	EAL domain
CI103_RS14190	COG1546	Belongs to the CinA family
CI103_RS14195	COG0071	Belongs to the small heat shock protein (HSP20) family
CI103_RS14210	COG2197	response regulator
CI103_RS14215	COG2135	peptidase activity
CI103_RS14220	COG2207	Transcriptional regulator
CI103_RS14235	COG4221	oxidoreductase activity
CI103_RS14240	COG1802	Transcriptional regulator
CI103_RS14245	COG0589	response to stress
CI103_RS14250	COG0246	Mannitol dehydrogenase
CI103_RS14255	COG2271	Major facilitator Superfamily
CI103_RS14270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CI103_RS14285	COG0243	molybdopterin cofactor binding
CI103_RS14290	COG0437	4 iron, 4 sulfur cluster binding
CI103_RS14295	COG3302	dmso reductase anchor subunit
CI103_RS14310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CI103_RS14315	COG1940	carbohydrate kinase activity
CI103_RS14320	COG0583	DNA-binding transcription factor activity
CI103_RS14325	COG2814	Major facilitator Superfamily
CI103_RS14330	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CI103_RS14345	COG3591	Belongs to the peptidase S1B family
CI103_RS14370	COG0628	permease
CI103_RS14400	COG0679	Auxin Efflux Carrier
CI103_RS14410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CI103_RS14435	COG3290	protein histidine kinase activity
CI103_RS14440	COG4565	transcriptional regulatory protein
CI103_RS14465	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CI103_RS14465	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CI103_RS14485	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CI103_RS14490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CI103_RS14500	COG0183	Belongs to the thiolase family
CI103_RS14505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CI103_RS14515	COG1414	Transcriptional regulator
CI103_RS14520	COG2840	Smr protein MutS2
CI103_RS14525	COG0583	DNA-binding transcription factor activity
CI103_RS14535	COG1473	amidohydrolase
CI103_RS14540	COG1473	amidohydrolase
CI103_RS14545	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CI103_RS14560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CI103_RS14575	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CI103_RS14580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CI103_RS14600	COG0531	amino acid
CI103_RS14610	COG3136	membrane protein required for alginate biosynthesis
CI103_RS14615	COG0745	RESPONSE REGULATOR receiver
CI103_RS14625	COG2205	protein histidine kinase activity
CI103_RS14635	COG0114	fumarate hydratase activity
CI103_RS14640	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CI103_RS14640	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CI103_RS14645	COG1482	cell wall glycoprotein biosynthetic process
CI103_RS14650	COG5339	Protein conserved in bacteria
CI103_RS14655	COG1609	Transcriptional regulator
CI103_RS14660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI103_RS14660	COG1263	PTS System
CI103_RS14665	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CI103_RS14690	COG2391	methyltransferase activity
CI103_RS14695	COG0425	Belongs to the sulfur carrier protein TusA family
CI103_RS14700	COG5562	phage envelope protein
CI103_RS14705	COG0401	homolog of Blt101
CI103_RS14710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CI103_RS14715	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS14720	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CI103_RS14730	COG0477	Major facilitator Superfamily
CI103_RS14735	COG1113	amino acid transport
CI103_RS14740	COG2988	succinylglutamate desuccinylase activity
CI103_RS14745	COG3724	N-succinylarginine dihydrolase activity
CI103_RS14750	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS14755	COG3138	arginine N-succinyltransferase
CI103_RS14760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CI103_RS14765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CI103_RS14770	COG0667	Aldo Keto reductase
CI103_RS14775	COG0583	DNA-binding transcription factor activity
CI103_RS14800	COG4122	O-methyltransferase activity
CI103_RS14805	COG1643	Atp-dependent helicase
CI103_RS14820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CI103_RS14825	COG3327	negative regulation of DNA-templated transcription, initiation
CI103_RS14830	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CI103_RS14835	COG0183	Belongs to the thiolase family
CI103_RS14840	COG2050	protein possibly involved in aromatic compounds catabolism
CI103_RS14845	COG1250	3-hydroxyacyl-CoA dehydrogenase
CI103_RS14850	COG1024	Enoyl-CoA hydratase
CI103_RS14855	COG1024	Enoyl-CoA hydratase
CI103_RS14860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CI103_RS14865	COG2151	metal-sulfur cluster biosynthetic enzyme
CI103_RS14870	COG3396	Phenylacetate-CoA oxygenase
CI103_RS14875	COG3460	Phenylacetate-CoA oxygenase
CI103_RS14880	COG3396	Phenylacetate-CoA oxygenase
CI103_RS14885	COG2030	dehydratase
CI103_RS14885	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS14910	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS14915	COG2207	Transcriptional regulator
CI103_RS14920	COG3784	Protein of unknown function (DUF1318)
CI103_RS14930	COG2911	Protein conserved in bacteria
CI103_RS14935	COG0586	Pfam SNARE associated Golgi protein
CI103_RS14940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CI103_RS14945	COG3187	Heat shock protein
CI103_RS14950	COG3042	response to heat
CI103_RS14960	COG0674	pyruvate-flavodoxin oxidoreductase activity
CI103_RS14960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CI103_RS14960	COG1013	pyruvate-flavodoxin oxidoreductase activity
CI103_RS14960	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CI103_RS14965	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CI103_RS14975	COG0589	response to stress
CI103_RS14985	COG0513	Belongs to the DEAD box helicase family
CI103_RS15005	COG1349	DNA-binding transcription factor activity
CI103_RS15010	COG0673	inositol 2-dehydrogenase activity
CI103_RS15025	COG1113	amino acid transport
CI103_RS15030	COG1522	sequence-specific DNA binding
CI103_RS15040	COG1448	Aminotransferase
CI103_RS15045	COG2011	ABC-type metal ion transport system permease component
CI103_RS15060	COG0436	Aminotransferase
CI103_RS15065	COG0604	alcohol dehydrogenase
CI103_RS15090	COG0583	DNA-binding transcription factor activity
CI103_RS15110	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS15115	COG1309	transcriptional regulator
CI103_RS15120	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS15215	COG2885	chlorophyll binding
CI103_RS15330	COG1196	nuclear chromosome segregation
CI103_RS15330	COG0741	lytic transglycosylase activity
CI103_RS15330	COG0739	heme binding
CI103_RS15410	COG3567	Phage-associated protein, HI1409 family
CI103_RS15415	COG1783	phage Terminase large subunit
CI103_RS15435	COG3772	lysozyme
CI103_RS15445	COG0484	heat shock protein binding
CI103_RS15545	COG0582	viral genome integration into host DNA
CI103_RS15550	COG0693	protein deglycase activity
CI103_RS15555	COG1078	dGTPase activity
CI103_RS15560	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS15565	COG0583	DNA-binding transcription factor activity
CI103_RS15585	COG0656	L-ascorbic acid biosynthetic process
CI103_RS15615	COG4166	transmembrane transport
CI103_RS15620	COG2866	Carboxypeptidase
CI103_RS15625	COG4948	Mandelate Racemase Muconate Lactonizing
CI103_RS15630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CI103_RS15635	COG3180	Ammonia monooxygenase
CI103_RS15645	COG1486	melibiose metabolic process
CI103_RS15650	COG0583	DNA-binding transcription factor activity
CI103_RS15660	COG3106	COG3106 Predicted ATPase
CI103_RS15670	COG1983	PspC domain protein
CI103_RS15680	COG1842	Phage shock protein A
CI103_RS15685	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CI103_RS15695	COG1473	amidohydrolase
CI103_RS15710	COG0702	epimerase
CI103_RS15725	COG2135	peptidase activity
CI103_RS15735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CI103_RS15740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CI103_RS15745	COG3344	reverse transcriptase
CI103_RS15770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CI103_RS15830	COG1196	nuclear chromosome segregation
CI103_RS15920	COG5484	DNA packaging
CI103_RS15920	COG3728	DNA packaging
CI103_RS15980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CI103_RS16090	COG4171	peptide transport system, permease
CI103_RS16105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CI103_RS16115	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CI103_RS16120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CI103_RS16120	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CI103_RS16135	COG1349	DNA-binding transcription factor activity
CI103_RS16145	COG0023	Translation Initiation Factor
CI103_RS16155	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CI103_RS16160	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CI103_RS16165	COG0671	phosphoesterase, PA-phosphatase related
CI103_RS16175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CI103_RS16205	COG0616	signal peptide processing
CI103_RS16215	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS16220	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CI103_RS16230	COG0583	DNA-binding transcription factor activity
CI103_RS16240	COG0009	L-threonylcarbamoyladenylate synthase
CI103_RS16250	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CI103_RS16255	COG0512	Glutamine amidotransferase of anthranilate synthase
CI103_RS16255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CI103_RS16260	COG0135	phosphoribosylanthranilate isomerase activity
CI103_RS16260	COG0134	indole-3-glycerol-phosphate synthase activity
CI103_RS16315	COG4774	siderophore transport
CI103_RS16325	COG3047	cAMP biosynthetic process
CI103_RS16330	COG0727	PFAM Uncharacterised protein family (UPF0153)
CI103_RS16360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CI103_RS16365	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS16370	COG1988	membrane-bound metal-dependent
CI103_RS16375	COG1823	symporter activity
CI103_RS16385	COG0753	catalase activity
CI103_RS16395	COG1486	melibiose metabolic process
CI103_RS16400	COG2169	Transcriptional regulator
CI103_RS16400	COG1917	Cupin 2, conserved barrel domain protein
CI103_RS16405	COG1447	Phosphotransferase system cellobiose-specific component IIA
CI103_RS16410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI103_RS16415	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI103_RS16420	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CI103_RS16430	COG0322	excinuclease ABC activity
CI103_RS16435	COG3678	ATP-independent chaperone mediated protein folding
CI103_RS16445	COG3724	N-succinylarginine dihydrolase activity
CI103_RS16455	COG3138	arginine N-succinyltransferase
CI103_RS16465	COG0708	Exodeoxyribonuclease III
CI103_RS16470	COG0398	Pfam SNARE associated Golgi protein
CI103_RS16475	COG0398	Pfam SNARE associated Golgi protein
CI103_RS16480	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CI103_RS16485	COG4134	Bacterial extracellular solute-binding protein
CI103_RS16490	COG4135	transport system, permease component
CI103_RS16495	COG4136	ATPase activity
CI103_RS16500	COG2897	thiosulfate sulfurtransferase activity
CI103_RS16505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CI103_RS16510	COG0494	nUDIX hydrolase
CI103_RS16515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CI103_RS16520	COG3321	synthase
CI103_RS16520	COG0604	alcohol dehydrogenase
CI103_RS16520	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS16525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CI103_RS16530	COG0709	Synthesizes selenophosphate from selenide and ATP
CI103_RS16550	COG0778	Nitroreductase
CI103_RS16555	COG0616	signal peptide processing
CI103_RS16560	COG0252	asparaginase activity
CI103_RS16565	COG1335	isochorismatase
CI103_RS16570	COG2814	Major facilitator Superfamily
CI103_RS16575	COG1349	DNA-binding transcription factor activity
CI103_RS16580	COG0667	Aldo Keto reductase
CI103_RS16585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI103_RS16590	COG0191	fructose-bisphosphate aldolase activity
CI103_RS16595	COG1063	alcohol dehydrogenase
CI103_RS16600	COG2271	Major facilitator Superfamily
CI103_RS16605	COG1063	alcohol dehydrogenase
CI103_RS16620	COG3139	Protein of unknown function (DUF1315)
CI103_RS16640	COG0656	L-ascorbic acid biosynthetic process
CI103_RS16645	COG3713	MltA-interacting MipA family protein
CI103_RS16650	COG2766	serine protein kinase
CI103_RS16665	COG0386	Belongs to the glutathione peroxidase family
CI103_RS16685	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS16690	COG0583	DNA-binding transcription factor activity
CI103_RS16695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CI103_RS16700	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CI103_RS16705	COG3344	reverse transcriptase
CI103_RS16720	COG0859	PFAM glycosyl transferase family 9
CI103_RS16725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CI103_RS16735	COG2207	Transcriptional regulator
CI103_RS16740	COG2807	transmembrane transport
CI103_RS16745	COG0504	CTP synthase activity
CI103_RS16750	COG1683	Conserved Protein
CI103_RS16755	COG3189	MarR family transcriptional regulator
CI103_RS16760	COG3042	response to heat
CI103_RS16765	COG2199	diguanylate cyclase activity
CI103_RS16765	COG2203	Gaf domain
CI103_RS16785	COG3182	Iron-regulated membrane protein
CI103_RS16795	COG1560	Kdo2-lipid A biosynthetic process
CI103_RS16810	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CI103_RS16815	COG3706	GGDEF domain
CI103_RS16820	COG0583	DNA-binding transcription factor activity
CI103_RS16825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CI103_RS16850	COG1294	oxidase, subunit
CI103_RS16855	COG1271	oxidase subunit
CI103_RS16860	COG3546	catalase activity
CI103_RS16865	COG3685	Protein conserved in bacteria
CI103_RS16870	COG3685	Protein conserved in bacteria
CI103_RS16875	COG3729	General stress protein
CI103_RS16880	COG1063	alcohol dehydrogenase
CI103_RS16885	COG3813	Protein conserved in bacteria
CI103_RS16900	COG0640	Transcriptional regulator
CI103_RS16905	COG0538	isocitrate dehydrogenase activity
CI103_RS16910	COG1187	pseudouridine synthase activity
CI103_RS16930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CI103_RS16950	COG2205	protein histidine kinase activity
CI103_RS16955	COG2850	peptidyl-arginine hydroxylation
CI103_RS16975	COG1177	transmembrane transport
CI103_RS16990	COG0318	PFAM AMP-dependent synthetase and ligase
CI103_RS17000	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CI103_RS17010	COG4591	ABC-type transport system involved in lipoprotein release permease component
CI103_RS17020	COG4591	ABC-type transport system involved in lipoprotein release permease component
CI103_RS17025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CI103_RS17030	COG1388	LysM domain
CI103_RS17030	COG1376	ErfK ybiS ycfS ynhG family protein
CI103_RS17040	COG1309	transcriptional regulator
CI103_RS17050	COG3134	Outer membrane lipoprotein
CI103_RS17055	COG1252	NADH dehydrogenase
CI103_RS17085	COG5633	Lipoprotein
CI103_RS17090	COG0537	adenosine 5'-monophosphoramidase activity
CI103_RS17100	COG0084	hydrolase, TatD family'
CI103_RS17105	COG0470	DNA polymerase III
CI103_RS17115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CI103_RS17120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CI103_RS17125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CI103_RS17140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CI103_RS17160	COG1399	metal-binding, possibly nucleic acid-binding protein
CI103_RS17175	COG1530	ribonuclease E activity
CI103_RS17180	COG0583	DNA-binding transcription factor activity
CI103_RS17185	COG2814	Major facilitator Superfamily
CI103_RS17205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CI103_RS17255	COG1560	Kdo2-lipid A biosynthetic process
CI103_RS17275	COG5645	(Lipo)protein
CI103_RS17315	COG3381	protein complex oligomerization
CI103_RS17345	COG0583	DNA-binding transcription factor activity
CI103_RS17355	COG1335	isochorismatase
CI103_RS17365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CI103_RS17370	COG1702	phosphate starvation-inducible protein PhoH
CI103_RS17390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CI103_RS17400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CI103_RS17415	COG1309	transcriptional regulator
CI103_RS17450	COG2233	PERMEase
CI103_RS17465	COG3729	General stress protein
CI103_RS17490	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS17505	COG0531	amino acid
CI103_RS17515	COG0174	glutamine synthetase
CI103_RS17520	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CI103_RS17525	COG1917	Cupin 2, conserved barrel domain protein
CI103_RS17525	COG1396	sequence-specific DNA binding
CI103_RS17530	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS17535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CI103_RS17540	COG0583	DNA-binding transcription factor activity
CI103_RS17545	COG0473	3-isopropylmalate dehydrogenase activity
CI103_RS17555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CI103_RS17560	COG4638	Rieske (2fe-2S)
CI103_RS17565	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS17570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CI103_RS17580	COG2200	EAL domain
CI103_RS17585	COG2200	EAL domain
CI103_RS17600	COG0670	Belongs to the BI1 family
CI103_RS17615	COG2207	Transcriptional regulator
CI103_RS17620	COG1881	PFAM PEBP family protein
CI103_RS17635	COG1832	CoA-binding protein
CI103_RS17645	COG0210	DNA helicase
CI103_RS17650	COG3304	Inner membrane component domain
CI103_RS17655	COG1289	transmembrane transporter activity
CI103_RS17660	COG3070	regulator of competence-specific genes
CI103_RS17685	COG1067	ATP-dependent peptidase activity
CI103_RS17695	COG3130	regulation of translation
CI103_RS17705	COG3009	Protein conserved in bacteria
CI103_RS17710	COG3008	intermembrane lipid transfer
CI103_RS17710	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CI103_RS17715	COG2995	paraquat-inducible protein a
CI103_RS17720	COG0488	(ABC) transporter
CI103_RS17730	COG3217	Mosc domain protein beta barrel domain protein
CI103_RS17730	COG0633	Ferredoxin
CI103_RS17745	COG0431	NADPH-dependent FMN reductase
CI103_RS17750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CI103_RS17755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CI103_RS17760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CI103_RS17770	COG0308	aminopeptidase N
CI103_RS17780	COG1473	amidohydrolase
CI103_RS17790	COG0814	amino acid
CI103_RS17800	COG1522	sequence-specific DNA binding
CI103_RS17815	COG1448	Aminotransferase
CI103_RS17820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CI103_RS17825	COG3108	Peptidase M15
CI103_RS17835	COG2989	Protein conserved in bacteria
CI103_RS17845	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CI103_RS17855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CI103_RS17860	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CI103_RS17865	COG3173	Aminoglycoside phosphotransferase
CI103_RS17880	COG3214	Protein conserved in bacteria
CI103_RS17895	COG2333	competence protein COMEC
CI103_RS17895	COG0658	competence protein
CI103_RS17905	COG0539	negative regulation of cytoplasmic translation
CI103_RS17925	COG2323	membrane
CI103_RS17930	COG1944	ATP diphosphatase activity
CI103_RS17935	COG2116	formate transmembrane transporter activity
CI103_RS17940	COG1882	Formate acetyltransferase
CI103_RS17945	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CI103_RS17950	COG0477	Major facilitator Superfamily
CI103_RS17960	COG3302	dmso reductase anchor subunit
CI103_RS17965	COG0437	4 iron, 4 sulfur cluster binding
CI103_RS17970	COG0243	molybdopterin cofactor binding
CI103_RS17980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CI103_RS17990	COG1674	ftsk spoiiie
CI103_RS17990	COG1178	ABC-type Fe3 transport system permease component
CI103_RS18005	COG0492	ferredoxin-NADP+ reductase activity
CI103_RS18010	COG4988	ABC transporter
CI103_RS18015	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CI103_RS18030	COG0542	response to heat
CI103_RS18040	COG1278	Cold shock
CI103_RS18055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI103_RS18060	COG3593	DNA synthesis involved in DNA repair
CI103_RS18070	COG2431	L-lysine efflux transmembrane transporter activity
CI103_RS18080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CI103_RS18095	COG0028	Belongs to the TPP enzyme family
CI103_RS18100	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CI103_RS18105	COG0702	epimerase
CI103_RS18110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CI103_RS18115	COG3023	N-Acetylmuramoyl-L-alanine amidase
CI103_RS18120	COG2203	Gaf domain
CI103_RS18120	COG5001	Diguanylate cyclase
CI103_RS18120	COG4251	negative regulation of phosphorylation
CI103_RS18120	COG3706	GGDEF domain
CI103_RS18135	COG1126	abc transporter atp-binding protein
CI103_RS18140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI103_RS18145	COG4215	(ABC) transporter
CI103_RS18150	COG4160	amino acid transport
CI103_RS18155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI103_RS18160	COG5002	protein histidine kinase activity
CI103_RS18165	COG0745	RESPONSE REGULATOR receiver
CI103_RS18180	COG1177	transmembrane transport
CI103_RS18185	COG1176	ABC-type spermidine putrescine transport system, permease component I
CI103_RS18190	COG3842	ATPase activity
CI103_RS18195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CI103_RS18395	COG4695	Portal protein
CI103_RS18430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CI103_RS18470	COG3344	reverse transcriptase
CI103_RS18480	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CI103_RS18485	COG3226	Transcriptional regulator
CI103_RS18490	COG0738	Major facilitator superfamily
CI103_RS18495	COG0561	phosphatase activity
CI103_RS18500	COG2814	Major facilitator Superfamily
CI103_RS18510	COG0671	phosphoesterase, PA-phosphatase related
CI103_RS18515	COG1349	DNA-binding transcription factor activity
CI103_RS18520	COG1686	Belongs to the peptidase S11 family
CI103_RS18525	COG0625	glutathione transferase activity
CI103_RS18530	COG2133	pyrroloquinoline quinone binding
CI103_RS18540	COG2223	nitrite transmembrane transporter activity
CI103_RS18565	COG0747	negative chemotaxis
CI103_RS18580	COG0303	'Molybdopterin
CI103_RS18585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CI103_RS18590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CI103_RS18595	COG1882	Formate acetyltransferase
CI103_RS18600	COG0561	phosphatase activity
CI103_RS18610	COG1609	Transcriptional regulator
CI103_RS18615	COG2271	Major facilitator Superfamily
CI103_RS18630	COG0488	(ABC) transporter
CI103_RS18635	COG2365	Tyrosine phosphatase family
CI103_RS18640	COG1376	ErfK ybiS ycfS ynhG family protein
CI103_RS18645	COG2188	Transcriptional regulator
CI103_RS18650	COG2723	6-phospho-beta-galactosidase activity
CI103_RS18655	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CI103_RS18660	COG1321	iron dependent repressor
CI103_RS18670	COG2194	sulfuric ester hydrolase activity
CI103_RS18675	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CI103_RS18690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI103_RS18695	COG0765	amino acid transport
CI103_RS18700	COG1126	abc transporter atp-binding protein
CI103_RS18705	COG0668	transmembrane transport
CI103_RS18715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CI103_RS18725	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CI103_RS18735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CI103_RS18740	COG1199	ATP-dependent helicase activity
CI103_RS18745	COG0513	Belongs to the DEAD box helicase family
CI103_RS18750	COG3958	Transketolase
CI103_RS18755	COG3959	Transketolase, thiamine diphosphate binding domain
CI103_RS18760	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS18765	COG2271	Major facilitator Superfamily
CI103_RS18770	COG0583	DNA-binding transcription factor activity
CI103_RS18775	COG1309	transcriptional regulator
CI103_RS18780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI103_RS18785	COG1131	(ABC) transporter
CI103_RS18790	COG0842	Transport permease protein
CI103_RS18795	COG0842	Transport permease protein
CI103_RS18805	COG3568	Endonuclease Exonuclease Phosphatase
CI103_RS18810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CI103_RS18815	COG0392	lysyltransferase activity
CI103_RS18820	COG0670	Belongs to the BI1 family
CI103_RS18825	COG0314	molybdopterin synthase activity
CI103_RS18830	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CI103_RS18840	COG0521	Mo-molybdopterin cofactor biosynthetic process
CI103_RS18865	COG0745	RESPONSE REGULATOR receiver
CI103_RS18870	COG0642	Histidine kinase
CI103_RS18905	COG2226	methyltransferase
CI103_RS18925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CI103_RS18930	COG1881	PFAM PEBP family protein
CI103_RS18970	COG4677	pectinesterase activity
CI103_RS19000	COG0789	Transcriptional regulator
CI103_RS19005	COG2200	EAL domain
CI103_RS19030	COG0561	phosphatase activity
CI103_RS19035	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CI103_RS19040	COG4149	molybdate abc transporter
CI103_RS19045	COG0725	ABC transporter, periplasmic molybdate-binding protein
CI103_RS19055	COG3585	molybdate ion transport
CI103_RS19055	COG2005	Transcriptional regulator
CI103_RS19060	COG1119	ATPase activity
CI103_RS19070	COG1085	galactose-1-phosphate uridylyltransferase
CI103_RS19080	COG2017	converts alpha-aldose to the beta-anomer
CI103_RS19090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CI103_RS19105	COG3201	nicotinamide mononucleotide transporter
CI103_RS19110	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CI103_RS19155	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CI103_RS19160	COG2885	chlorophyll binding
CI103_RS19170	COG3064	Membrane
CI103_RS19175	COG0848	biopolymer transport protein
CI103_RS19180	COG0811	peptide transport
CI103_RS19185	COG0824	Thioesterase
CI103_RS19190	COG3790	cyd operon protein YbgE
CI103_RS19195	COG4890	Cyd operon protein YbgT
CI103_RS19200	COG1294	oxidase, subunit
CI103_RS19205	COG1271	oxidase subunit
CI103_RS19215	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CI103_RS19225	COG0508	dehydrogenase complex catalyzes the overall conversion of
CI103_RS19230	COG0567	Dehydrogenase, E1 component
CI103_RS19235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CI103_RS19240	COG1053	succinate dehydrogenase
CI103_RS19245	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CI103_RS19250	COG2009	succinate dehydrogenase
CI103_RS19290	COG1984	allophanate hydrolase subunit 2
CI103_RS19295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CI103_RS19310	COG0415	Belongs to the DNA photolyase family
CI103_RS19340	COG2205	protein histidine kinase activity
CI103_RS19345	COG0745	RESPONSE REGULATOR receiver
CI103_RS19355	COG0033	Phosphoglucomutase
CI103_RS19365	COG0596	Alpha beta hydrolase
CI103_RS19380	COG0735	belongs to the Fur family
CI103_RS19425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CI103_RS19430	COG1846	Transcriptional regulator
CI103_RS19430	COG1940	carbohydrate kinase activity
CI103_RS19435	COG0647	UMP catabolic process
CI103_RS19440	COG0367	asparagine synthase
CI103_RS19485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CI103_RS19495	COG1702	phosphate starvation-inducible protein PhoH
CI103_RS19505	COG4535	Mg2 and Co2 transporter CorC
CI103_RS19520	COG0765	amino acid transport
CI103_RS19525	COG0765	amino acid transport
CI103_RS19530	COG1126	abc transporter atp-binding protein
CI103_RS19545	COG2888	peptidyl-tyrosine sulfation
CI103_RS19560	COG1466	dna polymerase III delta subunit
CI103_RS19580	COG0799	negative regulation of ribosome biogenesis
CI103_RS19590	COG0768	penicillin binding
CI103_RS19595	COG0772	Belongs to the SEDS family
CI103_RS19600	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CI103_RS19605	COG1686	Belongs to the peptidase S11 family
CI103_RS19620	COG0583	DNA-binding transcription factor activity
CI103_RS19635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CI103_RS19655	COG3069	C4-dicarboxylate transmembrane transporter activity
CI103_RS19660	COG3719	Belongs to the RNase T2 family
CI103_RS19665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CI103_RS19685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CI103_RS19690	COG0583	DNA-binding transcription factor activity
CI103_RS19695	COG3969	phosphoadenosine phosphosulfate
CI103_RS19700	COG1475	DNA binding
CI103_RS19705	COG0436	Aminotransferase
CI103_RS19730	COG1129	ABC transporter
CI103_RS19735	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS19740	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS19750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CI103_RS19765	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CI103_RS19775	COG0402	S-adenosylhomocysteine deaminase activity
CI103_RS19785	COG0483	inositol monophosphate 1-phosphatase activity
CI103_RS19790	COG2271	Major facilitator Superfamily
CI103_RS19820	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS19825	COG1129	ABC transporter
CI103_RS19830	COG0371	Dehydrogenase
CI103_RS19835	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS19850	COG2879	small protein
CI103_RS19855	COG1966	Carbon starvation protein
CI103_RS19865	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS19870	COG3433	isochorismatase activity
CI103_RS19870	COG1535	isochorismatase
CI103_RS19875	COG1021	2,3-dihydroxybenzoate-AMP ligase
CI103_RS19880	COG1169	isochorismate synthase
CI103_RS19885	COG4592	Periplasmic binding protein
CI103_RS19895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI103_RS19900	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI103_RS19905	COG1120	ATPase activity
CI103_RS19910	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CI103_RS19910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CI103_RS19915	COG3251	PFAM MbtH domain protein
CI103_RS19920	COG2382	esterase
CI103_RS19930	COG4771	TonB-dependent receptor
CI103_RS19935	COG2977	Belongs to the P-Pant transferase superfamily
CI103_RS19940	COG3958	Transketolase
CI103_RS19945	COG3959	Transketolase, thiamine diphosphate binding domain
CI103_RS19955	COG2390	Transcriptional regulator
CI103_RS19960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CI103_RS19965	COG1879	ABC-type sugar transport system periplasmic component
CI103_RS19975	COG1129	ABC transporter
CI103_RS19980	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS19990	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS20000	COG0583	DNA-binding transcription factor activity
CI103_RS20005	COG0668	transmembrane transport
CI103_RS20015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CI103_RS20045	COG0747	negative chemotaxis
CI103_RS20050	COG0601	transmembrane transport
CI103_RS20055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CI103_RS20060	COG0444	Belongs to the ABC transporter superfamily
CI103_RS20065	COG4608	Belongs to the ABC transporter superfamily
CI103_RS20075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CI103_RS20080	COG4221	oxidoreductase activity
CI103_RS20090	COG4215	(ABC) transporter
CI103_RS20095	COG0765	amino acid transport
CI103_RS20100	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CI103_RS20115	COG0697	spore germination
CI103_RS20125	COG3698	Phosphodiester glycosidase
CI103_RS20175	COG2315	Protein conserved in bacteria
CI103_RS20180	COG0778	Nitroreductase
CI103_RS20190	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI103_RS20200	COG3716	PTS system mannose fructose sorbose family IID component
CI103_RS20205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CI103_RS20210	COG2222	sugar isomerase
CI103_RS20215	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CI103_RS20215	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CI103_RS20235	COG0477	Major facilitator Superfamily
CI103_RS20240	COG0668	transmembrane transport
CI103_RS20270	COG3188	usher protein
CI103_RS20285	COG2771	luxR family
CI103_RS20295	COG0673	inositol 2-dehydrogenase activity
CI103_RS20305	COG2211	Major facilitator Superfamily
CI103_RS20310	COG1113	amino acid transport
CI103_RS20325	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS20330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CI103_RS20340	COG0531	amino acid
CI103_RS20390	COG0667	Aldo Keto reductase
CI103_RS20395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI103_RS20400	COG1473	amidohydrolase
CI103_RS20425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI103_RS20430	COG1120	ATPase activity
CI103_RS20435	COG1566	PFAM secretion protein HlyD family protein
CI103_RS20480	COG4211	Belongs to the binding-protein-dependent transport system permease family
CI103_RS20485	COG1129	ABC transporter
CI103_RS20500	COG0673	inositol 2-dehydrogenase activity
CI103_RS20530	COG3104	oligopeptide transport
CI103_RS20535	COG1982	Orn Lys Arg decarboxylase major
CI103_RS20540	COG0531	amino acid
CI103_RS20545	COG3710	Transcriptional regulator
CI103_RS20555	COG1560	Kdo2-lipid A biosynthetic process
CI103_RS20570	COG3188	usher protein
CI103_RS20575	COG3121	Chaperone
CI103_RS20580	COG3539	Fimbrial protein
CI103_RS20620	COG0582	viral genome integration into host DNA
CI103_RS20635	COG3344	reverse transcriptase
CI103_RS20820	COG3772	lysozyme
CI103_RS20890	COG0305	Participates in initiation and elongation during chromosome replication
CI103_RS20970	COG0582	viral genome integration into host DNA
CI103_RS20990	COG2501	S4 domain
CI103_RS21000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CI103_RS21020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CI103_RS21025	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CI103_RS21040	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CI103_RS21045	COG4181	ATPase activity
CI103_RS21050	COG2755	lipolytic protein G-D-S-L family
CI103_RS21055	COG0300	oxidoreductase activity
CI103_RS21060	COG3118	belongs to the thioredoxin family
CI103_RS21070	COG0390	transport system, permease component
CI103_RS21075	COG4619	ABC transporter
CI103_RS21080	COG0330	HflC and HflK could
CI103_RS21085	COG1585	Membrane protein implicated in regulation of membrane protease activity
CI103_RS21100	COG3735	TraB family
CI103_RS21105	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CI103_RS21115	COG2223	nitrite transmembrane transporter activity
CI103_RS21120	COG4651	solute:proton antiporter activity
CI103_RS21120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CI103_RS21125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI103_RS21165	COG2832	Protein of unknown function (DUF454)
CI103_RS21170	COG3923	Primosomal replication protein n
CI103_RS21180	COG5464	transposase or invertase
CI103_RS21185	COG3264	Mechanosensitive ion channel
CI103_RS21185	COG1196	nuclear chromosome segregation
CI103_RS21190	COG1309	transcriptional regulator
CI103_RS21195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI103_RS21200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CI103_RS21215	COG0110	maltose O-acetyltransferase activity
CI103_RS21260	COG1874	Beta-galactosidase
CI103_RS21265	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CI103_RS21270	COG3833	ABC-type maltose transport systems, permease component
CI103_RS21275	COG1175	transmembrane transport
CI103_RS21280	COG2182	Extracellular solute-binding protein
CI103_RS21290	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CI103_RS21305	COG2364	Membrane
CI103_RS21335	COG3695	enzyme binding
CI103_RS21340	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CI103_RS21345	COG1946	Acyl-CoA thioesterase
CI103_RS21350	COG0004	ammonium transporteR
CI103_RS21355	COG0347	Belongs to the P(II) protein family
CI103_RS21360	COG1132	(ABC) transporter
CI103_RS21365	COG1132	(ABC) transporter
CI103_RS21370	COG1522	sequence-specific DNA binding
CI103_RS21385	COG4533	DNA binding
CI103_RS21395	COG0824	Thioesterase
CI103_RS21400	COG1555	photosystem II stabilization
CI103_RS21405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CI103_RS21410	COG0776	regulation of translation
CI103_RS21415	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CI103_RS21445	COG0271	Belongs to the BolA IbaG family
CI103_RS21450	COG3056	Lipoprotein
CI103_RS21455	COG2223	nitrite transmembrane transporter activity
CI103_RS21460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CI103_RS21465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CI103_RS21470	COG1845	cytochrome c oxidase, subunit III
CI103_RS21475	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CI103_RS21490	COG1414	Transcriptional regulator
CI103_RS21495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CI103_RS21500	COG1053	succinate dehydrogenase
CI103_RS21510	COG1053	succinate dehydrogenase
CI103_RS21525	COG0673	inositol 2-dehydrogenase activity
CI103_RS21530	COG2814	Major facilitator Superfamily
CI103_RS21540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CI103_RS21545	COG0693	protein deglycase activity
CI103_RS21565	COG0142	geranyltranstransferase activity
CI103_RS21575	COG0667	Aldo Keto reductase
CI103_RS21580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CI103_RS21600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CI103_RS21600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CI103_RS21610	COG4238	major outer membrane lipoprotein
CI103_RS21630	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CI103_RS21635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CI103_RS21640	COG1862	Preprotein translocase
CI103_RS21660	COG0450	alkyl hydroperoxide reductase
CI103_RS21665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS21680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI103_RS21690	COG1228	amidohydrolase
CI103_RS21700	COG1335	isochorismatase
CI103_RS21705	COG0583	DNA-binding transcription factor activity
CI103_RS21710	COG0366	Alpha amylase catalytic
CI103_RS21735	COG0420	3'-5' exonuclease activity
CI103_RS21740	COG0419	ATPase involved in DNA repair
CI103_RS21745	COG1940	carbohydrate kinase activity
CI103_RS21760	COG4126	flavin adenine dinucleotide binding
CI103_RS21770	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CI103_RS21775	COG3416	Protein conserved in bacteria
CI103_RS21785	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CI103_RS21795	COG1785	Belongs to the alkaline phosphatase family
CI103_RS21835	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CI103_RS21840	COG1335	isochorismatase
CI103_RS21845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CI103_RS21850	COG0113	porphobilinogen synthase activity
CI103_RS21860	COG2175	clavaminate synthase activity
CI103_RS21865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CI103_RS21870	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CI103_RS21875	COG4521	taurine ABC transporter
CI103_RS21880	COG2040	homocysteine
CI103_RS21885	COG0833	amino acid
CI103_RS21895	COG4303	Ethanolamine ammonia lyase large subunit
CI103_RS21900	COG4302	ethanolamine ammonia-lyase activity
CI103_RS21935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI103_RS21940	COG1126	abc transporter atp-binding protein
CI103_RS21945	COG0765	amino acid transport
CI103_RS21950	COG0765	amino acid transport
CI103_RS21965	COG3188	usher protein
CI103_RS21990	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CI103_RS22000	COG3639	organic phosphonate transmembrane transporter activity
CI103_RS22025	COG0791	NLP P60 protein
CI103_RS22050	COG0582	viral genome integration into host DNA
CI103_RS22055	COG1192	Involved in chromosome partitioning
CI103_RS22115	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CI103_RS22120	COG0022	dehydrogenase e1 component
CI103_RS22125	COG0508	dehydrogenase complex catalyzes the overall conversion of
CI103_RS22130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CI103_RS22155	COG1070	Carbohydrate kinase
CI103_RS22160	COG1028	Short-chain dehydrogenase reductase Sdr
CI103_RS22165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CI103_RS22170	COG3775	system Galactitol-specific IIC component
CI103_RS22175	COG0625	glutathione transferase activity
CI103_RS22180	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CI103_RS22200	COG0579	oxidoreductase
CI103_RS22205	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS22210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CI103_RS22215	COG1113	amino acid transport
CI103_RS22220	COG1802	Transcriptional regulator
CI103_RS22240	COG2195	Cleaves the N-terminal amino acid of tripeptides
CI103_RS22245	COG0454	-acetyltransferase
CI103_RS22260	COG2991	Protein conserved in bacteria
CI103_RS22275	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CI103_RS22280	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CI103_RS22300	COG3034	peptidoglycan biosynthetic process
CI103_RS22305	COG0121	glutamine amidotransferase
CI103_RS22315	COG1960	acyl-CoA dehydrogenase activity
CI103_RS22320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CI103_RS22330	COG0583	DNA-binding transcription factor activity
CI103_RS22340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CI103_RS22350	COG2226	methyltransferase
CI103_RS22360	COG0741	lytic transglycosylase activity
CI103_RS22360	COG1388	LysM domain
CI103_RS22365	COG2226	methyltransferase
CI103_RS22375	COG2814	Major facilitator Superfamily
CI103_RS22380	COG0583	DNA-binding transcription factor activity
CI103_RS22385	COG0656	L-ascorbic acid biosynthetic process
CI103_RS22420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CI103_RS22430	COG2011	ABC-type metal ion transport system permease component
CI103_RS22435	COG1464	Belongs to the NlpA lipoprotein family
CI103_RS22445	COG1720	tRNA m6t6A37 methyltransferase activity
CI103_RS22455	COG0791	NLP P60 protein
CI103_RS22460	COG3015	lipoprotein NlpE involved in copper resistance
CI103_RS22465	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CI103_RS22480	COG4568	rho-dependent transcription termination
CI103_RS22490	COG0346	lactoylglutathione lyase activity
CI103_RS22495	COG1982	Orn Lys Arg decarboxylase major
CI103_RS22535	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CI103_RS22545	COG0750	zinc metalloprotease
CI103_RS22550	COG0575	Belongs to the CDS family
CI103_RS22565	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CI103_RS22590	COG0024	Methionine aminopeptidase
CI103_RS22595	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CI103_RS22610	COG3835	regulator
CI103_RS22615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CI103_RS22635	COG2860	membrane
CI103_RS22655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI103_RS22660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CI103_RS22665	COG1120	ATPase activity
CI103_RS22670	COG4774	siderophore transport
CI103_RS22675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CI103_RS22765	COG1643	Atp-dependent helicase
CI103_RS22770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CI103_RS22790	COG0617	tRNA 3'-terminal CCA addition
CI103_RS22795	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CI103_RS22815	COG0726	polysaccharide deacetylase
CI103_RS22820	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS22825	COG0842	Transport permease protein
CI103_RS22830	COG1131	(ABC) transporter
CI103_RS22835	COG0288	reversible hydration of carbon dioxide
CI103_RS22845	COG4993	Dehydrogenase
CI103_RS22850	COG2132	Multicopper oxidase
CI103_RS22900	COG3064	Membrane
CI103_RS22915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CI103_RS22920	COG0508	dehydrogenase complex catalyzes the overall conversion of
CI103_RS22925	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CI103_RS22930	COG2186	Transcriptional regulator
CI103_RS22935	COG1113	amino acid transport
CI103_RS22940	COG2211	Major facilitator Superfamily
CI103_RS22945	COG3940	Belongs to the glycosyl hydrolase 43 family
CI103_RS22950	COG3725	Membrane protein required for beta-lactamase induction
CI103_RS22955	COG3023	N-Acetylmuramoyl-L-alanine amidase
CI103_RS22965	COG4969	Belongs to the N-Me-Phe pilin family
CI103_RS22970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CI103_RS22975	COG1459	type II secretion system
CI103_RS23000	COG0494	nUDIX hydrolase
CI103_RS23020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CI103_RS23025	COG0849	cell division
CI103_RS23050	COG0772	Belongs to the SEDS family
CI103_RS23065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CI103_RS23070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CI103_RS23075	COG0768	penicillin binding
CI103_RS23100	COG1609	Transcriptional regulator
CI103_RS23110	COG0028	Belongs to the TPP enzyme family
CI103_RS23160	COG0738	Major facilitator superfamily
CI103_RS23170	COG0583	DNA-binding transcription factor activity
CI103_RS23175	COG2271	Major facilitator Superfamily
CI103_RS23180	COG2814	Major facilitator Superfamily
CI103_RS23200	COG1178	ABC-type Fe3 transport system permease component
CI103_RS23210	COG0586	Pfam SNARE associated Golgi protein
CI103_RS23230	COG0235	Class ii aldolase
CI103_RS23235	COG0417	DNA replication proofreading
CI103_RS23245	COG0564	pseudouridine synthase activity
CI103_RS23260	COG3493	citrate carrier protein
CI103_RS23275	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CI103_RS23280	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CI103_RS23290	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CI103_RS23345	COG0505	Belongs to the CarA family
CI103_RS23415	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CI103_RS23440	COG1047	Peptidyl-prolyl cis-trans
CI103_RS23455	COG0196	riboflavin kinase activity
CI103_RS23475	COG0583	DNA-binding transcription factor activity
CI103_RS23500	COG4735	regulation of single-species biofilm formation
CI103_RS23505	COG1584	GPR1 FUN34 yaaH family protein
CI103_RS23510	COG0477	Major facilitator Superfamily
CI103_RS23515	COG0521	Mo-molybdopterin cofactor biosynthetic process
CI103_RS23520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CI103_RS23525	COG1115	amino acid carrier protein
CI103_RS23540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CI103_RS23550	COG0460	homoserine dehydrogenase
CI103_RS23550	COG0527	aspartate kinase activity
CI103_RS23560	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CI103_RS23575	COG0745	RESPONSE REGULATOR receiver
CI103_RS23580	COG4452	Inner membrane protein CreD
CI103_RS23585	COG2205	protein histidine kinase activity
CI103_RS23590	COG0745	RESPONSE REGULATOR receiver
CI103_RS23595	COG3045	CreA protein
CI103_RS23600	COG3708	Transcriptional regulator
CI103_RS23600	COG2207	Transcriptional regulator
CI103_RS23620	COG0741	lytic transglycosylase activity
CI103_RS23630	COG0488	(ABC) transporter
CI103_RS23640	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CI103_RS23645	COG0560	Phosphoserine phosphatase
CI103_RS23655	COG3726	membrane protein affecting hemolysin expression
CI103_RS23685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CI103_RS23690	COG0084	hydrolase, TatD family'
CI103_RS23695	COG4667	esterase of the alpha-beta hydrolase superfamily
CI103_RS23705	COG2823	Periplasmic or secreted lipoprotein
CI103_RS23715	COG1011	Hydrolase
CI103_RS23720	COG0456	acetyltransferase
CI103_RS23725	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CI103_RS23755	COG3706	GGDEF domain
CI103_RS23760	COG4114	ferric iron reductase
CI103_RS23765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI103_RS23765	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI103_RS23770	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CI103_RS23775	COG2197	response regulator
CI103_RS23780	COG2197	response regulator
CI103_RS23800	COG2966	Psort location CytoplasmicMembrane, score
CI103_RS23815	COG1484	DNA-dependent DNA replication
CI103_RS23830	COG5464	transposase or invertase
CI103_RS23840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CI103_RS23845	COG3716	PTS system mannose fructose sorbose family IID component
CI103_RS23850	COG3715	PTS system
CI103_RS23865	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CI103_RS23865	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CI103_RS23875	COG1063	alcohol dehydrogenase
CI103_RS23880	COG1802	Transcriptional regulator
CI103_RS23885	COG2271	Major facilitator Superfamily
CI103_RS23890	COG0456	acetyltransferase
CI103_RS23890	COG1214	PFAM Peptidase M22, glycoprotease
CI103_RS23900	COG1737	Transcriptional regulator
CI103_RS23905	COG0800	Aldolase
CI103_RS23910	COG3734	2-keto-3-deoxy-galactonokinase
CI103_RS23925	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CI103_RS23955	COG1846	Transcriptional regulator
CI103_RS23960	COG0179	Fumarylacetoacetate (FAA) hydrolase
CI103_RS23970	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS23975	COG3384	dioxygenase
CI103_RS23985	COG3971	2-oxopent-4-enoate hydratase activity
CI103_RS24005	COG2368	4-hydroxyphenylacetate
CI103_RS24010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CI103_RS24025	COG1966	Carbon starvation protein
CI103_RS24030	COG2879	small protein
CI103_RS24035	COG0523	cobalamin synthesis protein
CI103_RS24045	COG1012	belongs to the aldehyde dehydrogenase family
CI103_RS24050	COG5464	transposase or invertase
CI103_RS24055	COG1917	Cupin 2, conserved barrel domain protein
CI103_RS24055	COG2207	Transcriptional regulator
CI103_RS24065	COG2733	membrane
CI103_RS24080	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CI103_RS24085	COG1924	4 iron, 4 sulfur cluster binding
CI103_RS24100	COG1566	PFAM secretion protein HlyD family protein
CI103_RS24110	COG5457	Domain of unknown function (DUF1127)
CI103_RS24115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CI103_RS24125	COG0583	DNA-binding transcription factor activity
CI103_RS24130	COG2249	NAD(P)H dehydrogenase (quinone) activity
CI103_RS24140	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS24145	COG1129	ABC transporter
CI103_RS24150	COG1879	ABC-type sugar transport system periplasmic component
CI103_RS24160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI103_RS24165	COG1129	ABC transporter
CI103_RS24165	COG0842	Transport permease protein
CI103_RS24170	COG0842	Transport permease protein
CI103_RS24200	COG2850	peptidyl-arginine hydroxylation
CI103_RS24215	COG5002	protein histidine kinase activity
CI103_RS24220	COG0745	RESPONSE REGULATOR receiver
CI103_RS24230	COG1538	Outer membrane efflux protein
CI103_RS24235	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI103_RS24240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI103_RS24245	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CI103_RS24255	COG3040	lipid binding
CI103_RS24260	COG0789	Transcriptional regulator
CI103_RS24270	COG0300	oxidoreductase activity
CI103_RS24285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CI103_RS24305	COG3272	Protein of unknown function (DUF1722)
CI103_RS24310	COG4580	involved in the transport of maltose and maltodextrins
CI103_RS24320	COG2211	Major facilitator Superfamily
CI103_RS24325	COG3507	Belongs to the glycosyl hydrolase 43 family
CI103_RS24370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CI103_RS24370	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CI103_RS24435	COG0582	viral genome integration into host DNA
CI103_RS24450	COG0288	reversible hydration of carbon dioxide
CI103_RS24455	COG0659	secondary active sulfate transmembrane transporter activity
CI103_RS24460	COG1064	alcohol dehydrogenase
CI103_RS24465	COG1175	transmembrane transport
CI103_RS24470	COG0395	ABC-type sugar transport system, permease component
CI103_RS24475	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CI103_RS24480	COG3842	ATPase activity
CI103_RS24485	COG1653	transport
CI103_RS24495	COG1082	Xylose isomerase domain protein TIM barrel
CI103_RS24505	COG3962	Belongs to the TPP enzyme family
CI103_RS24510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI103_RS24515	COG1737	Transcriptional regulator
CI103_RS24515	COG0837	glucose binding
CI103_RS24550	COG3718	enzyme involved in inositol metabolism
CI103_RS24565	COG0433	COG0433 Predicted ATPase
CI103_RS24570	COG0795	lipopolysaccharide-transporting ATPase activity
CI103_RS24575	COG0795	lipopolysaccharide-transporting ATPase activity
CI103_RS24590	COG2927	DNA polymerase III (CHI subunit)
CI103_RS24595	COG0525	valine-tRNA ligase activity
CI103_RS24620	COG2188	Transcriptional regulator
CI103_RS24625	COG1288	antiporter activity
CI103_RS24630	COG1228	amidohydrolase
CI103_RS24635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI103_RS24640	COG2222	sugar isomerase
CI103_RS24645	COG2731	YhcH YjgK YiaL family protein
CI103_RS24685	COG1263	PTS System
CI103_RS24685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CI103_RS24690	COG0366	Alpha amylase catalytic
CI103_RS24695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CI103_RS24700	COG1486	melibiose metabolic process
CI103_RS24720	COG0602	queuosine metabolic process
CI103_RS24725	COG2026	Addiction module toxin, RelE StbE family
CI103_RS24730	COG3077	Addiction module antitoxin, RelB DinJ family
CI103_RS24735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CI103_RS24735	COG3711	transcriptional antiterminator
CI103_RS24740	COG2706	6-phosphogluconolactonase activity
CI103_RS24755	COG3964	amidohydrolase
CI103_RS24790	COG0312	modulator of DNA gyrase
CI103_RS24810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CI103_RS24820	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS24825	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS24830	COG1129	ABC transporter
CI103_RS24835	COG1879	ABC-type sugar transport system periplasmic component
CI103_RS24855	COG2105	PFAM AIG2 family protein
CI103_RS24860	COG2911	Protein conserved in bacteria
CI103_RS24865	COG0729	surface antigen
CI103_RS24875	COG1253	flavin adenine dinucleotide binding
CI103_RS24890	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CI103_RS24905	COG1733	regulation of RNA biosynthetic process
CI103_RS24910	COG0702	epimerase
CI103_RS24920	COG0697	spore germination
CI103_RS24930	COG1113	amino acid transport
CI103_RS24935	COG0545	Peptidyl-prolyl cis-trans isomerase
CI103_RS24940	COG3061	Opacity-associated protein A
CI103_RS24950	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CI103_RS24955	COG2965	DNA replication, synthesis of RNA primer
CI103_RS25015	COG1073	alpha beta
CI103_RS25020	COG3650	response to hydrogen peroxide
CI103_RS25030	COG1960	acyl-CoA dehydrogenase activity
CI103_RS25035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CI103_RS25040	COG0557	exoribonuclease II activity
CI103_RS25055	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CI103_RS25065	COG0330	HflC and HflK could
CI103_RS25070	COG0330	HflC and HflK could
CI103_RS25075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CI103_RS25095	COG0860	N-Acetylmuramoyl-L-alanine amidase
CI103_RS25100	COG0802	atpase or kinase
CI103_RS25105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CI103_RS25105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CI103_RS25110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CI103_RS25135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CI103_RS25160	COG3264	Mechanosensitive ion channel
CI103_RS25160	COG1511	domain protein
CI103_RS25175	COG1053	succinate dehydrogenase
CI103_RS25180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CI103_RS25200	COG2076	Multidrug Resistance protein
CI103_RS25205	COG5510	response to toxic substance
CI103_RS25220	COG1509	lysine 2,3-aminomutase activity
CI103_RS25300	COG0531	amino acid
CI103_RS25305	COG3030	protein affecting phage T7 exclusion by the F plasmid
CI103_RS25315	COG1027	Aspartate ammonia-lyase
CI103_RS25320	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CI103_RS25335	COG1309	transcriptional regulator
CI103_RS25365	COG0457	Tetratricopeptide repeat
CI103_RS25370	COG0726	polysaccharide deacetylase
CI103_RS25370	COG1649	PFAM Uncharacterised BCR, COG1649
CI103_RS25375	COG1215	transferase activity, transferring glycosyl groups
CI103_RS25395	COG0861	Integral membrane protein TerC family
CI103_RS25430	COG1486	melibiose metabolic process
CI103_RS25440	COG2169	Transcriptional regulator
CI103_RS25455	COG2824	Alkylphosphonate utilization operon protein PhnA
CI103_RS25460	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CI103_RS25465	COG2188	Transcriptional regulator
CI103_RS25470	COG3624	Phosphonate C-P lyase system protein PhnG
CI103_RS25475	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CI103_RS25480	COG3626	phosphonate metabolism
CI103_RS25485	COG3627	carbon phosphorus lyase activity
CI103_RS25490	COG4107	phosphonate C-P lyase system protein PhnK
CI103_RS25495	COG4778	phosphonate C-P lyase system protein PhnL
CI103_RS25500	COG3454	Phosphonate metabolism
CI103_RS25510	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CI103_RS25520	COG4191	Histidine kinase
CI103_RS25520	COG0784	Response regulator, receiver
CI103_RS25525	COG1129	ABC transporter
CI103_RS25530	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS25565	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CI103_RS25570	COG1301	dicarboxylic acid transport
CI103_RS25580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CI103_RS25590	COG3162	membrane
CI103_RS25620	COG3539	Fimbrial protein
CI103_RS25625	COG1346	cytolysis
CI103_RS25630	COG1380	Effector of murein hydrolase LrgA
CI103_RS25635	COG0583	DNA-binding transcription factor activity
CI103_RS25640	COG0025	NhaP-type Na H and K H
CI103_RS25645	COG2252	PERMEase
CI103_RS25655	COG0625	glutathione transferase activity
CI103_RS25660	COG0789	Transcriptional regulator
CI103_RS25670	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CI103_RS25705	COG1234	tRNA 3'-trailer cleavage
CI103_RS25710	COG1609	Transcriptional regulator
CI103_RS25715	COG0483	inositol monophosphate 1-phosphatase activity
CI103_RS25730	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CI103_RS25750	COG4771	TonB-dependent receptor
CI103_RS25755	COG0741	lytic transglycosylase activity
CI103_RS25770	COG2315	Protein conserved in bacteria
CI103_RS25775	COG0432	Pfam Uncharacterised protein family UPF0047
CI103_RS25790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CI103_RS25795	COG0305	Participates in initiation and elongation during chromosome replication
CI103_RS25810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CI103_RS25820	COG0735	belongs to the Fur family
CI103_RS25825	COG3237	CsbD-like
CI103_RS25830	COG0534	Mate efflux family protein
CI103_RS25840	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CI103_RS25925	COG0251	oxidation-reduction process
CI103_RS25935	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CI103_RS25950	COG0527	aspartate kinase activity
CI103_RS26005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CI103_RS26035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CI103_RS26045	COG0456	acetyltransferase
CI103_RS26085	COG0151	Belongs to the GarS family
CI103_RS26095	COG4191	Histidine kinase
CI103_RS26100	COG3678	ATP-independent chaperone mediated protein folding
CI103_RS26135	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CI103_RS26150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CI103_RS26155	COG2104	thiamine diphosphate biosynthetic process
CI103_RS26175	COG3706	GGDEF domain
CI103_RS26185	COG1447	Phosphotransferase system cellobiose-specific component IIA
CI103_RS26190	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CI103_RS26230	COG0250	Participates in transcription elongation, termination and antitermination
CI103_RS26280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CI103_RS26310	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CI103_RS26320	COG1739	Uncharacterized protein family UPF0029
CI103_RS26365	COG0805	protein transport
CI103_RS26385	COG3165	ubiquinone biosynthetic process from chorismate
CI103_RS26415	COG0583	DNA-binding transcription factor activity
CI103_RS26420	COG0697	spore germination
CI103_RS26425	COG0561	phosphatase activity
CI103_RS26430	COG2267	carboxylic ester hydrolase activity
CI103_RS26435	COG1280	lysine exporter protein (LysE YggA)
CI103_RS26445	COG1280	lysine exporter protein (LysE YggA)
CI103_RS26480	COG0210	DNA helicase
CI103_RS26485	COG1011	Hydrolase
CI103_RS26515	COG3072	Adenylate cyclase
CI103_RS26530	COG2959	enzyme of heme biosynthesis
CI103_RS26535	COG3071	HemY protein
CI103_RS26580	COG2244	polysaccharide biosynthetic process
CI103_RS26585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CI103_RS26590	COG0456	acetyltransferase
CI103_RS26595	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CI103_RS26600	COG1088	dTDP-glucose 4,6-dehydratase activity
CI103_RS26605	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CI103_RS26610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CI103_RS26620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CI103_RS26625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CI103_RS26635	COG3118	belongs to the thioredoxin family
CI103_RS26670	COG1811	Na channel or pump
CI103_RS26680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CI103_RS26685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CI103_RS26695	COG0583	DNA-binding transcription factor activity
CI103_RS26700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CI103_RS26715	COG3978	acetolactate synthase activity
CI103_RS26735	COG3085	chromosome segregation
CI103_RS26810	COG0583	DNA-binding transcription factor activity
CI103_RS26835	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CI103_RS26850	COG3443	Belongs to the bacterial solute-binding protein 9 family
CI103_RS26855	COG2207	Transcriptional regulator
CI103_RS26865	COG0371	Dehydrogenase
CI103_RS26870	COG0697	spore germination
CI103_RS26880	COG0583	DNA-binding transcription factor activity
CI103_RS26890	COG0737	Belongs to the 5'-nucleotidase family
CI103_RS26900	COG0527	aspartate kinase activity
CI103_RS26900	COG0460	homoserine dehydrogenase
CI103_RS26905	COG0626	cystathionine gamma-synthase activity
CI103_RS26920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CI103_RS26925	COG1609	Transcriptional regulator
CI103_RS26930	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CI103_RS26945	COG1575	Belongs to the MenA family. Type 1 subfamily
CI103_RS26965	COG3678	ATP-independent chaperone mediated protein folding
CI103_RS26970	COG0745	RESPONSE REGULATOR receiver
CI103_RS26975	COG2205	protein histidine kinase activity
CI103_RS26980	COG2258	MOSC domain
CI103_RS26985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CI103_RS27030	COG1129	ABC transporter
CI103_RS27035	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS27040	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS27045	COG1454	alcohol dehydrogenase
CI103_RS27055	COG2211	Major facilitator Superfamily
CI103_RS27115	COG0205	6-phosphofructokinase activity
CI103_RS27135	COG0243	molybdopterin cofactor binding
CI103_RS27135	COG3383	formate dehydrogenase (NAD+) activity
CI103_RS27140	COG3383	formate dehydrogenase (NAD+) activity
CI103_RS27140	COG0243	molybdopterin cofactor binding
CI103_RS27145	COG0437	4 iron, 4 sulfur cluster binding
CI103_RS27150	COG2864	formate dehydrogenase
CI103_RS27165	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CI103_RS27170	COG0657	acetylesterase activity
CI103_RS27175	COG0456	acetyltransferase
CI103_RS27190	COG1011	Hydrolase
CI103_RS27210	COG3852	Histidine kinase
CI103_RS27225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CI103_RS27250	COG0204	Acyl-transferase
CI103_RS27260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CI103_RS27265	COG3084	Protein conserved in bacteria
CI103_RS27275	COG1763	Mo-molybdopterin cofactor biosynthetic process
CI103_RS27300	COG2186	Transcriptional regulator
CI103_RS27305	COG0477	Major facilitator Superfamily
CI103_RS27310	COG1609	Transcriptional regulator
CI103_RS27315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CI103_RS27325	COG1172	Belongs to the binding-protein-dependent transport system permease family
CI103_RS27330	COG1129	ABC transporter
CI103_RS27360	COG1522	sequence-specific DNA binding
CI103_RS27365	COG0716	FMN binding
CI103_RS27380	COG3312	ion transport
CI103_RS27430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CI103_RS27435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CI103_RS27440	COG0573	inorganic phosphate transmembrane transporter activity
CI103_RS27445	COG0581	inorganic phosphate transmembrane transporter activity
CI103_RS27450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CI103_RS27455	COG0704	Plays a role in the regulation of phosphate uptake
CI103_RS27470	COG2382	esterase
CI103_RS27475	COG0363	glucosamine-6-phosphate deaminase activity
CI103_RS27480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CI103_RS27490	COG2252	PERMEase
CI103_RS27495	COG0431	NADPH-dependent FMN reductase
CI103_RS27500	COG2091	lysine biosynthetic process via aminoadipic acid
CI103_RS27530	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CI103_RS27565	COG2203	Gaf domain
CI103_RS27565	COG2199	diguanylate cyclase activity
CI103_RS27570	COG1716	ATPase activity
CI103_RS27570	COG5001	Diguanylate cyclase
CI103_RS27585	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CI103_RS27595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CI103_RS27645	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CI103_RS27675	COG0739	heme binding
CI103_RS27685	COG2132	Multicopper oxidase
CI103_RS27690	COG3667	copper resistance
CI103_RS27695	COG2372	response to copper ion
CI103_RS27700	COG1276	copper resistance
CI103_RS27705	COG0745	RESPONSE REGULATOR receiver
CI103_RS27710	COG2205	protein histidine kinase activity
CI103_RS27730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CI103_RS27745	COG0431	NADPH-dependent FMN reductase
CI103_RS27775	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CI103_RS27840	COG2801	Transposase and inactivated derivatives
CI103_RS27850	COG0501	Belongs to the peptidase M48B family
CI103_RS27870	COG0542	response to heat
CI103_RS27875	COG0071	Belongs to the small heat shock protein (HSP20) family
CI103_RS27985	COG3173	Aminoglycoside phosphotransferase
CI103_RS28015	COG1695	Transcriptional regulator
CI103_RS28115	COG3429	Glucose-6-phosphate dehydrogenase subunit
CI103_RS28115	COG3409	Peptidoglycan-binding domain 1 protein
CI103_RS28125	COG3436	PFAM IS66 Orf2 family protein
CI103_RS28135	COG4372	Transposase
CI103_RS28150	COG4172	Belongs to the ABC transporter superfamily
CI103_RS28165	COG0601	transmembrane transport
CI103_RS28170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CI103_RS28195	COG1595	DNA-templated transcription, initiation
CI103_RS28200	COG3712	iron ion homeostasis
CI103_RS28205	COG4772	TonB-dependent receptor
CI103_RS28210	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CI103_RS28215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI103_RS28220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CI103_RS28225	COG1120	ATPase activity
CI103_RS28230	COG3436	PFAM IS66 Orf2 family protein
CI103_RS28250	COG1609	Transcriptional regulator
CI103_RS28260	COG2223	nitrite transmembrane transporter activity
CI103_RS28340	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CI103_RS28570	COG5499	transcription regulator containing HTH domain
CI103_RS28655	COG1475	DNA binding
CI103_RS28735	COG3344	reverse transcriptase
CI103_RS28815	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CI103_RS28925	COG5001	Diguanylate cyclase
CI103_RS28925	COG3300	MHYT domain
CI103_RS28965	COG4644	lycopene metabolic process
CI103_RS28990	COG5433	transposase activity
CI103_RS29025	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CI103_RS29100	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CI103_RS29380	COG1475	DNA binding
CI103_RS29545	COG1192	Involved in chromosome partitioning
CI103_RS29585	COG1349	DNA-binding transcription factor activity
CI103_RS29655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CI103_RS29660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CI103_RS29690	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CI103_RS29795	COG0484	heat shock protein binding