locus-tag	class	description
AKK42_RS00005	COG2186	Transcriptional regulator
AKK42_RS00010	COG0477	Major facilitator Superfamily
AKK42_RS00015	COG1609	Transcriptional regulator
AKK42_RS00020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AKK42_RS00030	COG1172	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS00035	COG1129	ABC transporter
AKK42_RS00065	COG1522	sequence-specific DNA binding
AKK42_RS00070	COG0716	FMN binding
AKK42_RS00085	COG3312	ion transport
AKK42_RS00145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AKK42_RS00150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AKK42_RS00155	COG0573	inorganic phosphate transmembrane transporter activity
AKK42_RS00160	COG0581	inorganic phosphate transmembrane transporter activity
AKK42_RS00165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AKK42_RS00170	COG0704	Plays a role in the regulation of phosphate uptake
AKK42_RS00185	COG2382	esterase
AKK42_RS00190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AKK42_RS00200	COG2252	PERMEase
AKK42_RS00205	COG0431	NADPH-dependent FMN reductase
AKK42_RS00210	COG2091	lysine biosynthetic process via aminoadipic acid
AKK42_RS00240	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AKK42_RS00270	COG0187	DNA topoisomerase II activity
AKK42_RS00275	COG0561	phosphatase activity
AKK42_RS00290	COG0823	Involved in the tonB-independent uptake of proteins
AKK42_RS00295	COG5645	(Lipo)protein
AKK42_RS00315	COG2188	Transcriptional regulator
AKK42_RS00330	COG2149	membrane
AKK42_RS00360	COG0583	DNA-binding transcription factor activity
AKK42_RS00365	COG2814	Major facilitator Superfamily
AKK42_RS00385	COG0028	Belongs to the TPP enzyme family
AKK42_RS00390	COG0440	acetolactate synthase activity
AKK42_RS00395	COG2197	response regulator
AKK42_RS00405	COG2271	Major facilitator Superfamily
AKK42_RS00435	COG2188	Transcriptional regulator
AKK42_RS00445	COG3842	ATPase activity
AKK42_RS00460	COG4580	involved in the transport of maltose and maltodextrins
AKK42_RS00465	COG1447	Phosphotransferase system cellobiose-specific component IIA
AKK42_RS00470	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AKK42_RS00470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AKK42_RS00480	COG1609	Transcriptional regulator
AKK42_RS00490	COG3384	dioxygenase
AKK42_RS00495	COG0583	DNA-binding transcription factor activity
AKK42_RS00500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AKK42_RS00505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AKK42_RS00510	COG2828	Protein conserved in bacteria
AKK42_RS00525	COG0697	spore germination
AKK42_RS00530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AKK42_RS00530	COG1263	PTS System
AKK42_RS00540	COG2814	Major facilitator Superfamily
AKK42_RS00550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AKK42_RS00585	COG1309	transcriptional regulator
AKK42_RS00595	COG0583	DNA-binding transcription factor activity
AKK42_RS00620	COG1464	Belongs to the NlpA lipoprotein family
AKK42_RS00635	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AKK42_RS00645	COG1064	alcohol dehydrogenase
AKK42_RS00655	COG0604	alcohol dehydrogenase
AKK42_RS00670	COG2211	Major facilitator Superfamily
AKK42_RS00675	COG1501	Belongs to the glycosyl hydrolase 31 family
AKK42_RS00685	COG1486	melibiose metabolic process
AKK42_RS00690	COG1263	PTS System
AKK42_RS00690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AKK42_RS00695	COG2982	Protein involved in outer membrane biogenesis
AKK42_RS00700	COG2233	PERMEase
AKK42_RS00710	COG0786	glutamate:sodium symporter activity
AKK42_RS00725	COG3074	FtsZ-dependent cytokinesis
AKK42_RS00730	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AKK42_RS00755	COG3152	Membrane
AKK42_RS00765	COG1494	fructose-1,6-bisphosphatase
AKK42_RS00770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AKK42_RS00775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKK42_RS00780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AKK42_RS00800	COG2860	membrane
AKK42_RS00810	COG2169	Transcriptional regulator
AKK42_RS00810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AKK42_RS00815	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AKK42_RS00825	COG1561	YicC-like family, N-terminal region
AKK42_RS00850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AKK42_RS00885	COG1519	Transferase
AKK42_RS00890	COG1216	Glycosyl transferase, family 2
AKK42_RS00895	COG0438	transferase activity, transferring glycosyl groups
AKK42_RS00905	COG0859	PFAM glycosyl transferase family 9
AKK42_RS00930	COG0859	PFAM glycosyl transferase family 9
AKK42_RS00955	COG0463	Glycosyl transferase, family 2
AKK42_RS00960	COG2861	carbohydrate metabolic process
AKK42_RS00965	COG4942	peptidase
AKK42_RS00975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AKK42_RS00980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AKK42_RS01000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AKK42_RS01010	COG2186	Transcriptional regulator
AKK42_RS01030	COG3722	fumarate hydratase activity
AKK42_RS01050	COG1566	PFAM secretion protein HlyD family protein
AKK42_RS01055	COG0625	glutathione transferase activity
AKK42_RS01065	COG3276	selenocysteine insertion sequence binding
AKK42_RS01075	COG2211	Major facilitator Superfamily
AKK42_RS01085	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AKK42_RS01090	COG3977	Valine--pyruvate aminotransferase
AKK42_RS01095	COG0366	Alpha amylase catalytic
AKK42_RS01100	COG2992	FlgJ-related protein
AKK42_RS01105	COG2207	Transcriptional regulator
AKK42_RS01105	COG1609	Transcriptional regulator
AKK42_RS01110	COG4214	carbohydrate transport
AKK42_RS01120	COG4213	ABC transporter substrate-binding protein
AKK42_RS01135	COG4682	membrane
AKK42_RS01140	COG3274	enterobacterial common antigen metabolic process
AKK42_RS01165	COG0488	(ABC) transporter
AKK42_RS01170	COG1278	Cold shock
AKK42_RS01175	COG2944	sequence-specific DNA binding
AKK42_RS01180	COG2814	Major facilitator Superfamily
AKK42_RS01200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AKK42_RS01210	COG1609	Transcriptional regulator
AKK42_RS01215	COG2885	chlorophyll binding
AKK42_RS01220	COG0243	molybdopterin cofactor binding
AKK42_RS01225	COG0456	acetyltransferase
AKK42_RS01230	COG2818	Glycosylase
AKK42_RS01235	COG5571	outer membrane autotransporter
AKK42_RS01240	COG2223	nitrite transmembrane transporter activity
AKK42_RS01265	COG0747	negative chemotaxis
AKK42_RS01270	COG0601	transmembrane transport
AKK42_RS01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AKK42_RS01280	COG0444	Belongs to the ABC transporter superfamily
AKK42_RS01285	COG4608	Belongs to the ABC transporter superfamily
AKK42_RS01300	COG2894	cell division
AKK42_RS01310	COG1215	transferase activity, transferring glycosyl groups
AKK42_RS01330	COG2194	sulfuric ester hydrolase activity
AKK42_RS01360	COG1215	transferase activity, transferring glycosyl groups
AKK42_RS01365	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AKK42_RS01370	COG0457	Tetratricopeptide repeat
AKK42_RS01370	COG3118	belongs to the thioredoxin family
AKK42_RS01380	COG2200	EAL domain
AKK42_RS01380	COG2199	diguanylate cyclase activity
AKK42_RS01390	COG0612	Peptidase, M16
AKK42_RS01405	COG2982	Protein involved in outer membrane biogenesis
AKK42_RS01410	COG0477	Major facilitator Superfamily
AKK42_RS01415	COG1295	ribonuclease BN
AKK42_RS01420	COG0583	DNA-binding transcription factor activity
AKK42_RS01425	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS01430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AKK42_RS01440	COG1454	alcohol dehydrogenase
AKK42_RS01450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AKK42_RS01455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AKK42_RS01460	COG0671	phosphoesterase, PA-phosphatase related
AKK42_RS01480	COG0589	response to stress
AKK42_RS01490	COG0306	phosphate transporter
AKK42_RS01495	COG2081	HI0933 family
AKK42_RS01500	COG2239	Acts as a magnesium transporter
AKK42_RS01510	COG1124	(ABC) transporter
AKK42_RS01520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AKK42_RS01525	COG0601	transmembrane transport
AKK42_RS01530	COG0747	negative chemotaxis
AKK42_RS01540	COG3479	Phenolic acid decarboxylase
AKK42_RS01580	COG0628	permease
AKK42_RS01585	COG0477	Major facilitator Superfamily
AKK42_RS01595	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AKK42_RS01610	COG3714	YhhN family
AKK42_RS01620	COG3776	membrane
AKK42_RS01625	COG0742	ribosomal rna small subunit methyltransferase
AKK42_RS01630	COG0552	protein localization to endoplasmic reticulum
AKK42_RS01635	COG2884	Cell division ATP-binding protein ftsE
AKK42_RS01640	COG2177	Part of the ABC transporter FtsEX involved in
AKK42_RS01655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AKK42_RS01665	COG0683	leucine binding
AKK42_RS01670	COG4907	membrane protein (DUF2207)
AKK42_RS01675	COG1704	LemA family
AKK42_RS01690	COG0683	leucine binding
AKK42_RS01695	COG0559	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS01735	COG0584	glycerophosphoryl diester phosphodiesterase
AKK42_RS01745	COG0405	Gamma-glutamyltransferase
AKK42_RS01750	COG1247	-acetyltransferase
AKK42_RS01760	COG0673	inositol 2-dehydrogenase activity
AKK42_RS01765	COG1741	Belongs to the pirin family
AKK42_RS01770	COG1609	Transcriptional regulator
AKK42_RS01775	COG3265	gluconokinase activity
AKK42_RS01780	COG2610	gluconate transmembrane transporter activity
AKK42_RS01790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AKK42_RS01815	COG0058	SHG alpha-glucan phosphorylase activity
AKK42_RS01820	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AKK42_RS01835	COG1349	DNA-binding transcription factor activity
AKK42_RS01845	COG0058	SHG alpha-glucan phosphorylase activity
AKK42_RS01850	COG1640	4-alpha-glucanotransferase
AKK42_RS01855	COG2610	gluconate transmembrane transporter activity
AKK42_RS01865	COG1040	competence protein
AKK42_RS01890	COG1918	ferrous iron import across plasma membrane
AKK42_RS01895	COG2183	response to ionizing radiation
AKK42_RS01900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AKK42_RS01930	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AKK42_RS01935	COG1011	Hydrolase
AKK42_RS01945	COG0494	nUDIX hydrolase
AKK42_RS01950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AKK42_RS01975	COG4796	Type ii and iii secretion system protein
AKK42_RS01990	COG3266	domain, Protein
AKK42_RS01995	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AKK42_RS02000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AKK42_RS02025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AKK42_RS02030	COG0402	S-adenosylhomocysteine deaminase activity
AKK42_RS02035	COG0738	Major facilitator superfamily
AKK42_RS02060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AKK42_RS02065	COG1289	transmembrane transporter activity
AKK42_RS02075	COG1765	OsmC-like protein
AKK42_RS02080	COG3954	Phosphoribulokinase
AKK42_RS02090	COG0429	hydrolase of the alpha beta-hydrolase fold
AKK42_RS02100	COG0488	(ABC) transporter
AKK42_RS02115	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AKK42_RS02120	COG1047	Peptidyl-prolyl cis-trans
AKK42_RS02130	COG0545	Peptidyl-prolyl cis-trans isomerase
AKK42_RS02135	COG2964	Protein conserved in bacteria
AKK42_RS02190	COG0051	transcription antitermination factor activity, RNA binding
AKK42_RS02215	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AKK42_RS02230	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AKK42_RS02295	COG0201	protein transport
AKK42_RS02315	COG0202	RNA polymerase activity
AKK42_RS02330	COG0789	Transcriptional regulator
AKK42_RS02360	COG0758	DNA mediated transformation
AKK42_RS02370	COG0551	DNA topoisomerase type I activity
AKK42_RS02390	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AKK42_RS02420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AKK42_RS02425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKK42_RS02430	COG1309	transcriptional regulator
AKK42_RS02450	COG4145	pantothenate transmembrane transporter activity
AKK42_RS02455	COG3924	membrane
AKK42_RS02460	COG0439	Biotin carboxylase
AKK42_RS02465	COG0511	ligase activity, forming carbon-carbon bonds
AKK42_RS02490	COG2199	diguanylate cyclase activity
AKK42_RS02490	COG2200	EAL domain
AKK42_RS02495	COG1077	Cell shape determining protein MreB Mrl
AKK42_RS02500	COG1792	Involved in formation and maintenance of cell shape
AKK42_RS02505	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AKK42_RS02515	COG1530	ribonuclease E activity
AKK42_RS02520	COG3164	Protein of unknown function
AKK42_RS02525	COG0312	modulator of DNA gyrase
AKK42_RS02530	COG0583	DNA-binding transcription factor activity
AKK42_RS02545	COG1289	transmembrane transporter activity
AKK42_RS02550	COG2732	(Barnase) inhibitor
AKK42_RS02575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKK42_RS02580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKK42_RS02585	COG3105	Protein conserved in bacteria
AKK42_RS02590	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AKK42_RS02605	COG0625	glutathione transferase activity
AKK42_RS02610	COG2969	positive regulation of protein catabolic process
AKK42_RS02640	COG2731	YhcH YjgK YiaL family protein
AKK42_RS02645	COG0493	'glutamate synthase
AKK42_RS02650	COG0067	glutamate synthase
AKK42_RS02650	COG0069	glutamate synthase activity
AKK42_RS02650	COG0070	glutamate synthase
AKK42_RS02655	COG1242	4 iron, 4 sulfur cluster binding
AKK42_RS02660	COG2271	Major facilitator Superfamily
AKK42_RS02665	COG1063	alcohol dehydrogenase
AKK42_RS02670	COG1312	Catalyzes the dehydration of D-mannonate
AKK42_RS02675	COG2198	Histidine kinase
AKK42_RS02675	COG0784	Response regulator, receiver
AKK42_RS02675	COG5002	protein histidine kinase activity
AKK42_RS02680	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AKK42_RS02685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AKK42_RS02690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS02700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS02705	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AKK42_RS02710	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AKK42_RS02715	COG1137	ATPase activity
AKK42_RS02720	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AKK42_RS02725	COG3117	lipopolysaccharide transmembrane transporter activity
AKK42_RS02730	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AKK42_RS02740	COG0530	calcium, potassium:sodium antiporter activity
AKK42_RS02745	COG1127	ABC transporter
AKK42_RS02750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AKK42_RS02755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AKK42_RS02760	COG2854	intermembrane phospholipid transfer
AKK42_RS02765	COG3113	response to antibiotic
AKK42_RS02770	COG5007	Belongs to the BolA IbaG family
AKK42_RS02780	COG3423	Transcriptional regulator
AKK42_RS02785	COG0142	geranyltranstransferase activity
AKK42_RS02800	COG0697	spore germination
AKK42_RS02810	COG2027	D-alanyl-D-alanine carboxypeptidase
AKK42_RS02820	COG1534	Rna-binding protein
AKK42_RS02830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AKK42_RS02835	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AKK42_RS02845	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AKK42_RS02890	COG0195	Participates in both transcription termination and antitermination
AKK42_RS02935	COG0814	amino acid
AKK42_RS02940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AKK42_RS02945	COG0826	peptidase U32
AKK42_RS02950	COG0826	peptidase U32
AKK42_RS02955	COG3154	lipid carrier protein
AKK42_RS02960	COG3153	acetyltransferase
AKK42_RS02975	COG0693	protein deglycase activity
AKK42_RS02980	COG0702	epimerase
AKK42_RS02985	COG0701	Predicted permease
AKK42_RS02990	COG2823	Periplasmic or secreted lipoprotein
AKK42_RS03010	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AKK42_RS03015	COG2721	sulfolactate sulfo-lyase activity
AKK42_RS03025	COG2084	Dehydrogenase
AKK42_RS03045	COG1741	Belongs to the pirin family
AKK42_RS03050	COG0583	DNA-binding transcription factor activity
AKK42_RS03055	COG3152	Membrane
AKK42_RS03060	COG0435	Glutathione S-transferase
AKK42_RS03065	COG2259	Doxx family
AKK42_RS03075	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AKK42_RS03080	COG4575	ribosome binding
AKK42_RS03085	COG1422	Protein of unknown function (DUF1090)
AKK42_RS03095	COG0586	Pfam SNARE associated Golgi protein
AKK42_RS03100	COG2186	Transcriptional regulator
AKK42_RS03105	COG2271	Major facilitator Superfamily
AKK42_RS03115	COG2721	sulfolactate sulfo-lyase activity
AKK42_RS03130	COG0861	Integral membrane protein TerC family
AKK42_RS03135	COG0673	inositol 2-dehydrogenase activity
AKK42_RS03140	COG1451	nucleotide metabolic process
AKK42_RS03160	COG1902	pentaerythritol trinitrate reductase activity
AKK42_RS03160	COG0446	pyridine nucleotide-disulphide oxidoreductase
AKK42_RS03210	COG1695	Transcriptional regulator
AKK42_RS03220	COG2375	cellular response to nickel ion
AKK42_RS03235	COG1461	Dihydroxyacetone kinase
AKK42_RS03240	COG2376	Dihydroxyacetone kinase
AKK42_RS03265	COG3247	response to pH
AKK42_RS03275	COG0784	Response regulator, receiver
AKK42_RS03275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKK42_RS03275	COG2205	protein histidine kinase activity
AKK42_RS03275	COG2198	Histidine kinase
AKK42_RS03280	COG2197	response regulator
AKK42_RS03305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AKK42_RS03310	COG0358	DNA primase activity
AKK42_RS03315	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AKK42_RS03380	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AKK42_RS03395	COG4991	sh3 domain protein
AKK42_RS03400	COG3025	triphosphatase activity
AKK42_RS03425	COG2960	long-chain fatty acid transporting porin activity
AKK42_RS03440	COG3384	dioxygenase
AKK42_RS03445	COG0754	glutathionylspermidine amidase activity
AKK42_RS03455	COG1538	Outer membrane efflux protein
AKK42_RS03460	COG0494	nUDIX hydrolase
AKK42_RS03465	COG3151	Protein conserved in bacteria
AKK42_RS03470	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AKK42_RS03475	COG3150	esterase
AKK42_RS03485	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AKK42_RS03490	COG2249	NAD(P)H dehydrogenase (quinone) activity
AKK42_RS03495	COG0642	Histidine kinase
AKK42_RS03505	COG3111	PFAM Bacterial OB fold (BOF) protein
AKK42_RS03510	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AKK42_RS03520	COG0204	Acyl-transferase
AKK42_RS03525	COG2132	Multicopper oxidase
AKK42_RS03530	COG1032	radical SAM domain protein
AKK42_RS03535	COG0656	L-ascorbic acid biosynthetic process
AKK42_RS03540	COG1979	alcohol dehydrogenase
AKK42_RS03545	COG2207	Transcriptional regulator
AKK42_RS03550	COG0586	Pfam SNARE associated Golgi protein
AKK42_RS03570	COG0848	biopolymer transport protein
AKK42_RS03575	COG2211	Major facilitator Superfamily
AKK42_RS03600	COG0625	glutathione transferase activity
AKK42_RS03615	COG0754	glutathionylspermidine amidase activity
AKK42_RS03620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AKK42_RS03640	COG0583	DNA-binding transcription factor activity
AKK42_RS03645	COG0626	cystathionine gamma-synthase activity
AKK42_RS03660	COG1811	Na channel or pump
AKK42_RS03665	COG1982	Orn Lys Arg decarboxylase major
AKK42_RS03670	COG2211	Major facilitator Superfamily
AKK42_RS03685	COG1194	a g-specific adenine glycosylase
AKK42_RS03695	COG3171	Protein conserved in bacteria
AKK42_RS03710	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AKK42_RS03715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AKK42_RS03720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AKK42_RS03735	COG0762	integral membrane protein
AKK42_RS03740	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AKK42_RS03745	COG2805	Type II/IV secretion system protein
AKK42_RS03770	COG0189	ligase activity
AKK42_RS03775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AKK42_RS03780	COG2356	endonuclease I
AKK42_RS03790	COG2814	Major facilitator Superfamily
AKK42_RS03820	COG2146	nitrite reductase [NAD(P)H] activity
AKK42_RS03835	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS03840	COG1414	Transcriptional regulator
AKK42_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS03875	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AKK42_RS03895	COG0501	Belongs to the peptidase M48B family
AKK42_RS03900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AKK42_RS03915	COG0191	fructose-bisphosphate aldolase activity
AKK42_RS03920	COG0668	transmembrane transport
AKK42_RS03935	COG2968	Membrane
AKK42_RS03955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AKK42_RS03960	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AKK42_RS03975	COG0006	proline dipeptidase activity
AKK42_RS03980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AKK42_RS03985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AKK42_RS04005	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS04010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AKK42_RS04030	COG2723	6-phospho-beta-galactosidase activity
AKK42_RS04035	COG1737	Transcriptional regulator
AKK42_RS04045	COG1272	protein, Hemolysin III
AKK42_RS04055	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AKK42_RS04065	COG0716	FMN binding
AKK42_RS04070	COG4974	Belongs to the 'phage' integrase family
AKK42_RS04080	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AKK42_RS04100	COG4942	peptidase
AKK42_RS04110	COG2814	Major facilitator Superfamily
AKK42_RS04125	COG0667	Aldo Keto reductase
AKK42_RS04130	COG2249	NAD(P)H dehydrogenase (quinone) activity
AKK42_RS04165	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AKK42_RS04170	COG1393	Belongs to the ArsC family
AKK42_RS04185	COG1538	Outer membrane efflux protein
AKK42_RS04190	COG1289	transmembrane transporter activity
AKK42_RS04205	COG3592	Divergent 4Fe-4S mono-cluster
AKK42_RS04210	COG2388	GCN5-related N-acetyl-transferase
AKK42_RS04220	COG3539	Fimbrial protein
AKK42_RS04225	COG3539	Fimbrial protein
AKK42_RS04230	COG3539	Fimbrial protein
AKK42_RS04235	COG3188	usher protein
AKK42_RS04240	COG3121	Chaperone
AKK42_RS04245	COG3539	Fimbrial protein
AKK42_RS04255	COG4974	Belongs to the 'phage' integrase family
AKK42_RS04260	COG0582	viral genome integration into host DNA
AKK42_RS04275	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AKK42_RS04280	COG1846	Transcriptional regulator
AKK42_RS04285	COG0697	spore germination
AKK42_RS04335	COG0667	Aldo Keto reductase
AKK42_RS04340	COG0814	amino acid
AKK42_RS04355	COG0183	Belongs to the thiolase family
AKK42_RS04365	COG0823	Involved in the tonB-independent uptake of proteins
AKK42_RS04370	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS04375	COG2814	Major facilitator Superfamily
AKK42_RS04410	COG3842	ATPase activity
AKK42_RS04415	COG0395	ABC-type sugar transport system, permease component
AKK42_RS04420	COG1175	transmembrane transport
AKK42_RS04425	COG1917	Cupin 2, conserved barrel domain protein
AKK42_RS04430	COG1794	racemase activity, acting on amino acids and derivatives
AKK42_RS04435	COG0583	DNA-binding transcription factor activity
AKK42_RS04445	COG1609	Transcriptional regulator
AKK42_RS04450	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AKK42_RS04455	COG2723	6-phospho-beta-galactosidase activity
AKK42_RS04460	COG2186	Transcriptional regulator
AKK42_RS04470	COG1609	Transcriptional regulator
AKK42_RS04490	COG0667	Aldo Keto reductase
AKK42_RS04500	COG0861	Integral membrane protein TerC family
AKK42_RS04535	COG2165	general secretion pathway protein
AKK42_RS04540	COG4795	General secretion pathway protein
AKK42_RS04550	COG4967	type IV pilus modification protein PilV
AKK42_RS04555	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AKK42_RS04560	COG1025	Belongs to the peptidase M16 family
AKK42_RS04565	COG1074	ATP-dependent DNA helicase activity
AKK42_RS04570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AKK42_RS04580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AKK42_RS04580	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AKK42_RS04585	COG0860	N-Acetylmuramoyl-L-alanine amidase
AKK42_RS04590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AKK42_RS04620	COG4656	Part of a membrane complex involved in electron transport
AKK42_RS04625	COG1454	alcohol dehydrogenase
AKK42_RS04625	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS04640	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AKK42_RS04655	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AKK42_RS04820	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AKK42_RS04825	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AKK42_RS04830	COG2166	iron-sulfur cluster assembly
AKK42_RS04835	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AKK42_RS04845	COG0583	DNA-binding transcription factor activity
AKK42_RS04850	COG2363	Small membrane protein
AKK42_RS04860	COG1349	DNA-binding transcription factor activity
AKK42_RS04880	COG0738	Major facilitator superfamily
AKK42_RS04890	COG0235	Class ii aldolase
AKK42_RS04895	COG1454	alcohol dehydrogenase
AKK42_RS04915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AKK42_RS04930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AKK42_RS04935	COG2011	ABC-type metal ion transport system permease component
AKK42_RS04940	COG1464	Belongs to the NlpA lipoprotein family
AKK42_RS04945	COG0477	Major facilitator Superfamily
AKK42_RS04955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AKK42_RS04960	COG1760	l-serine dehydratase
AKK42_RS04965	COG0814	amino acid
AKK42_RS04970	COG1611	Belongs to the LOG family
AKK42_RS04985	COG3098	single-species biofilm formation
AKK42_RS04990	COG0564	pseudouridine synthase activity
AKK42_RS04995	COG0716	FMN binding
AKK42_RS05000	COG2271	Major facilitator Superfamily
AKK42_RS05005	COG4948	Mandelate Racemase Muconate Lactonizing
AKK42_RS05010	COG4948	Mandelate Racemase Muconate Lactonizing
AKK42_RS05015	COG1929	Belongs to the glycerate kinase type-1 family
AKK42_RS05020	COG4999	Histidine kinase
AKK42_RS05020	COG2205	protein histidine kinase activity
AKK42_RS05020	COG3437	response regulator, receiver
AKK42_RS05020	COG3850	Histidine kinase
AKK42_RS05030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AKK42_RS05035	COG3956	TIGRFAM MazG family protein
AKK42_RS05055	COG0602	queuosine metabolic process
AKK42_RS05060	COG0720	synthase
AKK42_RS05080	COG2234	aminopeptidase activity
AKK42_RS05140	COG1388	LysM domain
AKK42_RS05140	COG4942	peptidase
AKK42_RS05145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AKK42_RS05170	COG0163	prenyltransferase activity
AKK42_RS05175	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AKK42_RS05210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKK42_RS05215	COG4558	Periplasmic binding protein
AKK42_RS05220	COG3720	iron ion transport
AKK42_RS05240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AKK42_RS05245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AKK42_RS05250	COG1121	(ABC) transporter
AKK42_RS05260	COG1609	Transcriptional regulator
AKK42_RS05265	COG1940	carbohydrate kinase activity
AKK42_RS05270	COG1447	Phosphotransferase system cellobiose-specific component IIA
AKK42_RS05275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AKK42_RS05280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AKK42_RS05285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AKK42_RS05290	COG4580	involved in the transport of maltose and maltodextrins
AKK42_RS05300	COG2723	6-phospho-beta-galactosidase activity
AKK42_RS05310	COG0309	Hydrogenase expression formation protein (HypE)
AKK42_RS05315	COG0409	Hydrogenase expression formation protein
AKK42_RS05320	COG0298	carbon dioxide binding
AKK42_RS05325	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AKK42_RS05340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AKK42_RS05345	COG0651	ATP synthesis coupled electron transport
AKK42_RS05350	COG0650	Formate hydrogenlyase subunit 4
AKK42_RS05355	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AKK42_RS05355	COG3261	NADH dehydrogenase
AKK42_RS05360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AKK42_RS05365	COG3260	NADH ubiquinone oxidoreductase 20
AKK42_RS05375	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AKK42_RS05385	COG2723	6-phospho-beta-galactosidase activity
AKK42_RS05390	COG1263	PTS System
AKK42_RS05390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AKK42_RS05400	COG1609	Transcriptional regulator
AKK42_RS05405	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AKK42_RS05410	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AKK42_RS05415	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AKK42_RS05425	COG2814	Major facilitator Superfamily
AKK42_RS05435	COG1414	Transcriptional regulator
AKK42_RS05440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AKK42_RS05445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AKK42_RS05475	COG1349	DNA-binding transcription factor activity
AKK42_RS05480	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS05485	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS05495	COG3732	PTS system glucitol sorbitol-specific
AKK42_RS05500	COG3730	PTS system glucitol sorbitol-specific
AKK42_RS05505	COG2951	lytic endotransglycosylase activity
AKK42_RS05510	COG1121	(ABC) transporter
AKK42_RS05515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AKK42_RS05520	COG0803	Belongs to the bacterial solute-binding protein 9 family
AKK42_RS05525	COG1546	Belongs to the CinA family
AKK42_RS05545	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AKK42_RS05575	COG2823	Periplasmic or secreted lipoprotein
AKK42_RS05580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AKK42_RS05585	COG1238	metal cluster binding
AKK42_RS05605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AKK42_RS05610	COG2814	Major facilitator Superfamily
AKK42_RS05615	COG1566	PFAM secretion protein HlyD family protein
AKK42_RS05625	COG1846	Transcriptional regulator
AKK42_RS05640	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AKK42_RS05650	COG4176	ABC-type proline glycine betaine transport system permease component
AKK42_RS05665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKK42_RS05675	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AKK42_RS05680	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AKK42_RS05690	COG4575	ribosome binding
AKK42_RS05725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AKK42_RS05730	COG0640	Transcriptional regulator
AKK42_RS05740	COG0583	DNA-binding transcription factor activity
AKK42_RS05745	COG0671	phosphoesterase, PA-phosphatase related
AKK42_RS05750	COG3284	Transcriptional regulator
AKK42_RS05765	COG3121	Chaperone
AKK42_RS05780	COG3121	Chaperone
AKK42_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS05810	COG0235	Class ii aldolase
AKK42_RS05820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKK42_RS05845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AKK42_RS05875	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AKK42_RS05895	COG0431	NADPH-dependent FMN reductase
AKK42_RS05910	COG2271	Major facilitator Superfamily
AKK42_RS05915	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AKK42_RS05920	COG0477	Major facilitator Superfamily
AKK42_RS05925	COG3622	Belongs to the hyi family
AKK42_RS05950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKK42_RS05955	COG3708	Transcriptional regulator
AKK42_RS05955	COG2207	Transcriptional regulator
AKK42_RS05965	COG0583	DNA-binding transcription factor activity
AKK42_RS05980	COG2814	Major facilitator Superfamily
AKK42_RS05985	COG0028	Belongs to the TPP enzyme family
AKK42_RS05995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AKK42_RS06015	COG2814	Major facilitator Superfamily
AKK42_RS06130	COG0582	viral genome integration into host DNA
AKK42_RS06140	COG2867	negative regulation of translational initiation
AKK42_RS06160	COG0497	DNA recombination
AKK42_RS06175	COG4536	flavin adenine dinucleotide binding
AKK42_RS06180	COG4137	Cytochrome C assembly protein
AKK42_RS06185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AKK42_RS06225	COG2885	chlorophyll binding
AKK42_RS06230	COG2199	diguanylate cyclase activity
AKK42_RS06240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AKK42_RS06245	COG1605	Chorismate mutase
AKK42_RS06245	COG0287	Prephenate dehydrogenase
AKK42_RS06255	COG0077	Prephenate dehydratase
AKK42_RS06255	COG1605	Chorismate mutase
AKK42_RS06260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AKK42_RS06265	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AKK42_RS06280	COG0542	response to heat
AKK42_RS06305	COG0477	Major facilitator Superfamily
AKK42_RS06310	COG5544	Lipoprotein
AKK42_RS06315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AKK42_RS06325	COG3148	PFAM DTW domain containing protein
AKK42_RS06330	COG3118	belongs to the thioredoxin family
AKK42_RS06335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKK42_RS06350	COG0513	Belongs to the DEAD box helicase family
AKK42_RS06360	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AKK42_RS06370	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AKK42_RS06375	COG3026	antisigma factor binding
AKK42_RS06380	COG3086	response to oxidative stress
AKK42_RS06390	COG0681	Belongs to the peptidase S26 family
AKK42_RS06415	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AKK42_RS06425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AKK42_RS06430	COG1737	Transcriptional regulator
AKK42_RS06435	COG0560	Phosphoserine phosphatase
AKK42_RS06450	COG0047	phosphoribosylformylglycinamidine synthase activity
AKK42_RS06450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AKK42_RS06455	COG2205	protein histidine kinase activity
AKK42_RS06460	COG3170	Tfp pilus assembly protein FimV
AKK42_RS06465	COG2204	response regulator
AKK42_RS06470	COG0347	Belongs to the P(II) protein family
AKK42_RS06475	COG1017	nitric oxide dioxygenase activity
AKK42_RS06475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AKK42_RS06485	COG2259	Doxx family
AKK42_RS06490	COG2814	Major facilitator Superfamily
AKK42_RS06495	COG3711	transcriptional antiterminator
AKK42_RS06500	COG3683	transport system, periplasmic component
AKK42_RS06505	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AKK42_RS06535	COG0822	iron-sulfur transferase activity
AKK42_RS06555	COG0633	Ferredoxin
AKK42_RS06560	COG2975	iron-sulfur cluster assembly
AKK42_RS06585	COG2897	thiosulfate sulfurtransferase activity
AKK42_RS06590	COG2373	Large extracellular alpha-helical protein
AKK42_RS06595	COG4953	penicillin-binding protein 1C
AKK42_RS06625	COG2976	Protein conserved in bacteria
AKK42_RS06645	COG1645	bacterial-type flagellum-dependent swarming motility
AKK42_RS06655	COG0516	GMP reductase activity
AKK42_RS06655	COG0517	IMP dehydrogenase activity
AKK42_RS06680	COG2200	EAL domain
AKK42_RS06695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AKK42_RS06710	COG2723	6-phospho-beta-galactosidase activity
AKK42_RS06720	COG2233	PERMEase
AKK42_RS06735	COG1393	Belongs to the ArsC family
AKK42_RS06740	COG4783	chaperone-mediated protein folding
AKK42_RS06750	COG0628	permease
AKK42_RS06755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKK42_RS06760	COG2716	regulation of RNA biosynthetic process
AKK42_RS06770	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AKK42_RS06780	COG2321	neutral zinc metallopeptidase
AKK42_RS06785	COG1444	tRNA N-acetyltransferase activity
AKK42_RS06790	COG0400	carboxylic ester hydrolase activity
AKK42_RS06805	COG1393	Belongs to the ArsC family
AKK42_RS06810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AKK42_RS06815	COG0493	'glutamate synthase
AKK42_RS06815	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AKK42_RS06825	COG5342	invasion associated locus B
AKK42_RS06830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AKK42_RS06835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AKK42_RS06850	COG0860	N-Acetylmuramoyl-L-alanine amidase
AKK42_RS06870	COG2837	iron assimilation
AKK42_RS06885	COG4150	thiosulfate binding
AKK42_RS06890	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AKK42_RS06895	COG4208	sulfate ABC transporter
AKK42_RS06900	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AKK42_RS06910	COG4319	ketosteroid isomerase
AKK42_RS06950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AKK42_RS06975	COG3530	Putative quorum-sensing-regulated virulence factor
AKK42_RS06980	COG0385	Bile acid
AKK42_RS06985	COG0583	DNA-binding transcription factor activity
AKK42_RS07015	COG3415	Transposase
AKK42_RS07020	COG3415	Transposase
AKK42_RS07035	COG2200	EAL domain
AKK42_RS07035	COG2199	diguanylate cyclase activity
AKK42_RS07040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AKK42_RS07055	COG0667	Aldo Keto reductase
AKK42_RS07060	COG3961	Belongs to the TPP enzyme family
AKK42_RS07075	COG3279	Response regulator of the LytR AlgR family
AKK42_RS07080	COG3275	phosphorelay sensor kinase activity
AKK42_RS07090	COG0436	Aminotransferase
AKK42_RS07095	COG2807	transmembrane transport
AKK42_RS07100	COG0590	tRNA wobble adenosine to inosine editing
AKK42_RS07105	COG0583	DNA-binding transcription factor activity
AKK42_RS07120	COG3706	GGDEF domain
AKK42_RS07130	COG2116	formate transmembrane transporter activity
AKK42_RS07135	COG2853	Lipoprotein
AKK42_RS07145	COG3691	Protein conserved in bacteria
AKK42_RS07160	COG2062	phosphohistidine phosphatase, SixA
AKK42_RS07185	COG0730	response to heat
AKK42_RS07190	COG3101	peptidyl-lysine hydroxylation
AKK42_RS07205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AKK42_RS07225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AKK42_RS07235	COG0586	Pfam SNARE associated Golgi protein
AKK42_RS07245	COG0285	dihydrofolate synthase activity
AKK42_RS07250	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AKK42_RS07255	COG1286	toxin biosynthetic process
AKK42_RS07260	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AKK42_RS07265	COG0163	prenyltransferase activity
AKK42_RS07290	COG4160	amino acid transport
AKK42_RS07295	COG4598	ABC transporter
AKK42_RS07310	COG1090	epimerase
AKK42_RS07315	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AKK42_RS07320	COG0625	glutathione transferase activity
AKK42_RS07325	COG0625	glutathione transferase activity
AKK42_RS07330	COG0622	Phosphoesterase
AKK42_RS07335	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AKK42_RS07360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AKK42_RS07365	COG0490	domain, Protein
AKK42_RS07365	COG0471	metal ion transport
AKK42_RS07375	COG0436	Aminotransferase
AKK42_RS07380	COG0583	DNA-binding transcription factor activity
AKK42_RS07430	COG0839	Belongs to the complex I subunit 6 family
AKK42_RS07440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AKK42_RS07445	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AKK42_RS07460	COG2153	protein acetylation
AKK42_RS07465	COG1169	isochorismate synthase
AKK42_RS07515	COG0642	Histidine kinase
AKK42_RS07525	COG5464	transposase or invertase
AKK42_RS07540	COG1414	Transcriptional regulator
AKK42_RS07550	COG2271	Major facilitator Superfamily
AKK42_RS07560	COG0247	lactate metabolic process
AKK42_RS07570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AKK42_RS07575	COG2271	Major facilitator Superfamily
AKK42_RS07580	COG0584	glycerophosphoryl diester phosphodiesterase
AKK42_RS07585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AKK42_RS07620	COG0642	Histidine kinase
AKK42_RS07620	COG2198	Histidine kinase
AKK42_RS07635	COG2169	Transcriptional regulator
AKK42_RS07635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AKK42_RS07640	COG3145	DNA-N1-methyladenine dioxygenase activity
AKK42_RS07645	COG4615	Cyclic peptide transporter
AKK42_RS07650	COG2239	Acts as a magnesium transporter
AKK42_RS07655	COG0659	secondary active sulfate transmembrane transporter activity
AKK42_RS07670	COG0628	permease
AKK42_RS07695	COG1349	DNA-binding transcription factor activity
AKK42_RS07700	COG0494	nUDIX hydrolase
AKK42_RS07720	COG1061	Type III restriction enzyme res subunit
AKK42_RS07725	COG1187	pseudouridine synthase activity
AKK42_RS07730	COG2814	Major facilitator Superfamily
AKK42_RS07740	COG4172	Belongs to the ABC transporter superfamily
AKK42_RS07745	COG4239	(ABC) transporter, permease
AKK42_RS07750	COG4174	ABC transporter (Permease)
AKK42_RS07755	COG4166	transmembrane transport
AKK42_RS07760	COG2200	EAL domain
AKK42_RS07765	COG0791	NLP P60 protein
AKK42_RS07770	COG0671	phosphoesterase, PA-phosphatase related
AKK42_RS07775	COG0523	cobalamin synthesis protein
AKK42_RS07780	COG0246	Mannitol dehydrogenase
AKK42_RS07785	COG1312	Catalyzes the dehydration of D-mannonate
AKK42_RS07810	COG1566	PFAM secretion protein HlyD family protein
AKK42_RS07815	COG2814	Major facilitator Superfamily
AKK42_RS07820	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS07820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS07825	COG1105	Belongs to the carbohydrate kinase PfkB family
AKK42_RS07830	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AKK42_RS07830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AKK42_RS07830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AKK42_RS07840	COG2855	membrane
AKK42_RS07850	COG0583	DNA-binding transcription factor activity
AKK42_RS07855	COG0833	amino acid
AKK42_RS07860	COG4771	TonB-dependent receptor
AKK42_RS07875	COG2311	Membrane
AKK42_RS07890	COG1129	ABC transporter
AKK42_RS07900	COG2949	membrane
AKK42_RS07910	COG1346	cytolysis
AKK42_RS07920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AKK42_RS07925	COG3659	wide pore channel activity
AKK42_RS07940	COG2723	6-phospho-beta-galactosidase activity
AKK42_RS07950	COG1538	Outer membrane efflux protein
AKK42_RS07955	COG0586	Pfam SNARE associated Golgi protein
AKK42_RS07965	COG1686	Belongs to the peptidase S11 family
AKK42_RS07975	COG0277	FAD linked oxidase domain protein
AKK42_RS07980	COG1472	Belongs to the glycosyl hydrolase 3 family
AKK42_RS07985	COG1732	Glycine betaine
AKK42_RS07990	COG1174	glycine betaine transport
AKK42_RS07995	COG1125	glycine betaine transport
AKK42_RS08000	COG1174	glycine betaine transport
AKK42_RS08010	COG3275	phosphorelay sensor kinase activity
AKK42_RS08020	COG4807	Protein conserved in bacteria
AKK42_RS08040	COG5455	response to cobalt ion
AKK42_RS08045	COG0583	DNA-binding transcription factor activity
AKK42_RS08050	COG2252	PERMEase
AKK42_RS08060	COG0583	DNA-binding transcription factor activity
AKK42_RS08080	COG0351	phosphomethylpyrimidine kinase
AKK42_RS08085	COG1830	Aldolase
AKK42_RS08120	COG1070	Carbohydrate kinase
AKK42_RS08130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AKK42_RS08135	COG4948	Mandelate Racemase Muconate Lactonizing
AKK42_RS08140	COG0747	negative chemotaxis
AKK42_RS08145	COG0601	transmembrane transport
AKK42_RS08150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AKK42_RS08155	COG0444	Belongs to the ABC transporter superfamily
AKK42_RS08160	COG4608	Belongs to the ABC transporter superfamily
AKK42_RS08170	COG0826	peptidase U32
AKK42_RS08175	COG0745	RESPONSE REGULATOR receiver
AKK42_RS08180	COG2205	protein histidine kinase activity
AKK42_RS08205	COG1301	dicarboxylic acid transport
AKK42_RS08225	COG2205	protein histidine kinase activity
AKK42_RS08230	COG0443	Heat shock 70 kDa protein
AKK42_RS08235	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AKK42_RS08250	COG2982	Protein involved in outer membrane biogenesis
AKK42_RS08255	COG1253	flavin adenine dinucleotide binding
AKK42_RS08295	COG1216	Glycosyl transferase, family 2
AKK42_RS08300	COG0438	transferase activity, transferring glycosyl groups
AKK42_RS08310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AKK42_RS08335	COG1088	dTDP-glucose 4,6-dehydratase activity
AKK42_RS08385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AKK42_RS08410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AKK42_RS08415	COG0583	DNA-binding transcription factor activity
AKK42_RS08420	COG0531	amino acid
AKK42_RS08425	COG0640	Transcriptional regulator
AKK42_RS08430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AKK42_RS08435	COG2925	Exonuclease
AKK42_RS08450	COG1289	transmembrane transporter activity
AKK42_RS08470	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AKK42_RS08480	COG1942	4-Oxalocrotonate Tautomerase
AKK42_RS08485	COG0583	DNA-binding transcription factor activity
AKK42_RS08490	COG0095	Lipoate-protein ligase
AKK42_RS08495	COG0477	Major facilitator Superfamily
AKK42_RS08505	COG3300	MHYT domain
AKK42_RS08505	COG5001	Diguanylate cyclase
AKK42_RS08510	COG3615	Tellurite resistance protein tehB
AKK42_RS08535	COG3706	GGDEF domain
AKK42_RS08555	COG0534	Mate efflux family protein
AKK42_RS08565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AKK42_RS08585	COG0604	alcohol dehydrogenase
AKK42_RS08590	COG1309	transcriptional regulator
AKK42_RS08595	COG0025	NhaP-type Na H and K H
AKK42_RS08615	COG1376	ErfK ybiS ycfS ynhG family protein
AKK42_RS08635	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AKK42_RS08645	COG1418	mRNA catabolic process
AKK42_RS08650	COG0270	DNA (cytosine-5-)-methyltransferase activity
AKK42_RS08655	COG3727	T/G mismatch-specific endonuclease activity
AKK42_RS08660	COG0697	spore germination
AKK42_RS08665	COG2354	Protein conserved in bacteria
AKK42_RS08695	COG0366	Alpha amylase catalytic
AKK42_RS08700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKK42_RS08710	COG0765	amino acid transport
AKK42_RS08715	COG1126	abc transporter atp-binding protein
AKK42_RS08720	COG2197	response regulator
AKK42_RS08730	COG2197	response regulator
AKK42_RS08765	COG3318	Belongs to the UPF0149 family
AKK42_RS08765	COG3012	SEC-C Motif Domain Protein
AKK42_RS08770	COG0814	amino acid
AKK42_RS08780	COG1528	Iron-storage protein
AKK42_RS08795	COG0477	Major facilitator Superfamily
AKK42_RS08805	COG2211	Major facilitator Superfamily
AKK42_RS08805	COG2211	Major facilitator Superfamily
AKK42_RS08815	COG1528	Iron-storage protein
AKK42_RS08820	COG1879	ABC-type sugar transport system periplasmic component
AKK42_RS08830	COG1172	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS08855	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AKK42_RS08865	COG3102	Protein conserved in bacteria
AKK42_RS08885	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AKK42_RS08890	COG1801	Protein of unknown function DUF72
AKK42_RS08895	COG1335	isochorismatase
AKK42_RS08905	COG0494	nUDIX hydrolase
AKK42_RS08930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AKK42_RS08940	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AKK42_RS08945	COG0739	heme binding
AKK42_RS08950	COG1560	Kdo2-lipid A biosynthetic process
AKK42_RS08970	COG3493	citrate carrier protein
AKK42_RS08980	COG1737	Transcriptional regulator
AKK42_RS08990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AKK42_RS08995	COG0129	dihydroxy-acid dehydratase activity
AKK42_RS09000	COG0800	Aldolase
AKK42_RS09010	COG3141	response to X-ray
AKK42_RS09015	COG2979	Protein of unknown function (DUF533)
AKK42_RS09020	COG1770	oligopeptidase
AKK42_RS09025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AKK42_RS09035	COG2372	response to copper ion
AKK42_RS09040	COG1276	copper resistance
AKK42_RS09055	COG2990	Protein conserved in bacteria
AKK42_RS09080	COG3008	intermembrane lipid transfer
AKK42_RS09085	COG2995	paraquat-inducible protein a
AKK42_RS09090	COG1956	GAF domain-containing protein
AKK42_RS09110	COG2814	Major facilitator Superfamily
AKK42_RS09115	COG1414	Transcriptional regulator
AKK42_RS09145	COG0768	penicillin binding
AKK42_RS09150	COG2226	methyltransferase
AKK42_RS09165	COG3716	PTS system mannose fructose sorbose family IID component
AKK42_RS09170	COG3715	PTS system
AKK42_RS09175	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS09175	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AKK42_RS09180	COG1253	flavin adenine dinucleotide binding
AKK42_RS09185	COG2200	EAL domain
AKK42_RS09190	COG1760	l-serine dehydratase
AKK42_RS09210	COG0251	oxidation-reduction process
AKK42_RS09215	COG1199	ATP-dependent helicase activity
AKK42_RS09225	COG3065	identical protein binding
AKK42_RS09235	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AKK42_RS09245	COG2894	cell division
AKK42_RS09265	COG0179	Fumarylacetoacetate (FAA) hydrolase
AKK42_RS09295	COG2719	SpoVR family
AKK42_RS09320	COG1619	proteins homologs of microcin C7 resistance protein MccF
AKK42_RS09340	COG4774	siderophore transport
AKK42_RS09350	COG2211	Major facilitator Superfamily
AKK42_RS09360	COG2308	Evidence 4 Homologs of previously reported genes of
AKK42_RS09380	COG3842	ATPase activity
AKK42_RS09385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AKK42_RS09390	COG0395	ABC-type sugar transport system, permease component
AKK42_RS09400	COG1653	transport
AKK42_RS09405	COG1940	carbohydrate kinase activity
AKK42_RS09420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AKK42_RS09430	COG1174	glycine betaine transport
AKK42_RS09445	COG0583	DNA-binding transcription factor activity
AKK42_RS09450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AKK42_RS09465	COG1882	Formate acetyltransferase
AKK42_RS09500	COG0583	DNA-binding transcription factor activity
AKK42_RS09530	COG0583	DNA-binding transcription factor activity
AKK42_RS09540	COG0564	pseudouridine synthase activity
AKK42_RS09545	COG3122	Protein conserved in bacteria
AKK42_RS09575	COG0012	GTP binding
AKK42_RS09595	COG0659	secondary active sulfate transmembrane transporter activity
AKK42_RS09625	COG2890	protein-(glutamine-N5) methyltransferase activity
AKK42_RS09645	COG0387	Pfam Sodium calcium exchanger
AKK42_RS09650	COG4572	Cation transport regulator
AKK42_RS09655	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AKK42_RS09665	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AKK42_RS09670	COG3707	response regulator
AKK42_RS09680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AKK42_RS09690	COG1116	anion transmembrane transporter activity
AKK42_RS09695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AKK42_RS09695	COG2146	nitrite reductase [NAD(P)H] activity
AKK42_RS09700	COG0243	molybdopterin cofactor binding
AKK42_RS09705	COG4932	domain protein
AKK42_RS09710	COG2197	response regulator
AKK42_RS09715	COG3850	Histidine kinase
AKK42_RS09720	COG2223	nitrite transmembrane transporter activity
AKK42_RS09725	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AKK42_RS09730	COG1140	nitrate reductase beta subunit
AKK42_RS09735	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AKK42_RS09740	COG2181	nitrate reductase activity
AKK42_RS09750	COG1522	sequence-specific DNA binding
AKK42_RS09765	COG0788	formyltetrahydrofolate deformylase activity
AKK42_RS09775	COG1752	Esterase of the alpha-beta hydrolase superfamily
AKK42_RS09780	COG0745	RESPONSE REGULATOR receiver
AKK42_RS09785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AKK42_RS09790	COG2916	Histone family protein nucleoid-structuring protein H-NS
AKK42_RS09800	COG1435	thymidine kinase activity
AKK42_RS09805	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS09805	COG1454	alcohol dehydrogenase
AKK42_RS09815	COG2095	MarC family integral membrane protein
AKK42_RS09825	COG4166	transmembrane transport
AKK42_RS09830	COG0601	transmembrane transport
AKK42_RS09835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AKK42_RS09840	COG0444	Belongs to the ABC transporter superfamily
AKK42_RS09850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AKK42_RS09870	COG2353	YceI-like domain
AKK42_RS09880	COG2350	Protein conserved in bacteria
AKK42_RS09890	COG3001	Fructosamine kinase
AKK42_RS09900	COG1105	Belongs to the carbohydrate kinase PfkB family
AKK42_RS09905	COG3137	Salt-induced outer membrane protein
AKK42_RS09940	COG0072	phenylalanine-tRNA ligase activity
AKK42_RS09940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AKK42_RS09960	COG0583	DNA-binding transcription factor activity
AKK42_RS09980	COG0386	Belongs to the glutathione peroxidase family
AKK42_RS09990	COG0791	NLP P60 protein
AKK42_RS10000	COG4256	Hemin uptake protein
AKK42_RS10005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AKK42_RS10020	COG0574	Belongs to the PEP-utilizing enzyme family
AKK42_RS10020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AKK42_RS10025	COG0628	permease
AKK42_RS10030	COG0247	lactate metabolic process
AKK42_RS10030	COG0277	FAD linked oxidase domain protein
AKK42_RS10035	COG2050	protein possibly involved in aromatic compounds catabolism
AKK42_RS10040	COG2261	transglycosylase associated protein
AKK42_RS10055	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AKK42_RS10065	COG1120	ATPase activity
AKK42_RS10070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKK42_RS10080	COG0583	DNA-binding transcription factor activity
AKK42_RS10105	COG1304	FMN binding
AKK42_RS10120	COG0316	Belongs to the HesB IscA family
AKK42_RS10125	COG0719	Fe-S assembly protein
AKK42_RS10130	COG0396	ATPase activity
AKK42_RS10135	COG0719	Fe-S assembly protein
AKK42_RS10150	COG1376	ErfK ybiS ycfS ynhG family protein
AKK42_RS10175	COG1309	transcriptional regulator
AKK42_RS10180	COG1082	Xylose isomerase domain protein TIM barrel
AKK42_RS10180	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AKK42_RS10185	COG2271	Major facilitator Superfamily
AKK42_RS10190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AKK42_RS10200	COG1120	ATPase activity
AKK42_RS10205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKK42_RS10210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AKK42_RS10215	COG1414	Transcriptional regulator
AKK42_RS10250	COG2814	Major facilitator Superfamily
AKK42_RS10270	COG0583	DNA-binding transcription factor activity
AKK42_RS10275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AKK42_RS10295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AKK42_RS10300	COG1116	anion transmembrane transporter activity
AKK42_RS10305	COG4774	siderophore transport
AKK42_RS10310	COG1120	ATPase activity
AKK42_RS10315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKK42_RS10320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKK42_RS10325	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AKK42_RS10345	COG0765	amino acid transport
AKK42_RS10350	COG1126	abc transporter atp-binding protein
AKK42_RS10375	COG1473	amidohydrolase
AKK42_RS10380	COG3383	formate dehydrogenase (NAD+) activity
AKK42_RS10385	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AKK42_RS10400	COG1175	transmembrane transport
AKK42_RS10430	COG4133	protoheme IX ABC transporter activity
AKK42_RS10435	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AKK42_RS10440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AKK42_RS10455	COG1138	Cytochrome C-type biogenesis protein
AKK42_RS10465	COG3088	subunit of a heme lyase
AKK42_RS10465	COG4235	cytochrome complex assembly
AKK42_RS10505	COG0667	Aldo Keto reductase
AKK42_RS10510	COG2249	NAD(P)H dehydrogenase (quinone) activity
AKK42_RS10520	COG0656	L-ascorbic acid biosynthetic process
AKK42_RS10545	COG0667	Aldo Keto reductase
AKK42_RS10550	COG0667	Aldo Keto reductase
AKK42_RS10560	COG0667	Aldo Keto reductase
AKK42_RS10565	COG0583	DNA-binding transcription factor activity
AKK42_RS10570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AKK42_RS10570	COG2190	(PTS) system
AKK42_RS10570	COG1263	PTS System
AKK42_RS10575	COG2723	6-phospho-beta-galactosidase activity
AKK42_RS10605	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS10610	COG2610	gluconate transmembrane transporter activity
AKK42_RS10615	COG1250	3-hydroxyacyl-CoA dehydrogenase
AKK42_RS10625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AKK42_RS10635	COG0583	DNA-binding transcription factor activity
AKK42_RS10665	COG2814	Major facilitator Superfamily
AKK42_RS10690	COG0277	FAD linked oxidase domain protein
AKK42_RS10695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AKK42_RS10720	COG0402	S-adenosylhomocysteine deaminase activity
AKK42_RS10750	COG0583	DNA-binding transcription factor activity
AKK42_RS10775	COG4608	Belongs to the ABC transporter superfamily
AKK42_RS10780	COG0444	Belongs to the ABC transporter superfamily
AKK42_RS10810	COG2011	ABC-type metal ion transport system permease component
AKK42_RS10825	COG0346	lactoylglutathione lyase activity
AKK42_RS10830	COG1349	DNA-binding transcription factor activity
AKK42_RS10845	COG3321	synthase
AKK42_RS10845	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS10845	COG0604	alcohol dehydrogenase
AKK42_RS10870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AKK42_RS10890	COG0300	oxidoreductase activity
AKK42_RS10925	COG0307	riboflavin synthase, alpha
AKK42_RS10930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AKK42_RS10935	COG2814	Major facilitator Superfamily
AKK42_RS10940	COG0583	DNA-binding transcription factor activity
AKK42_RS10950	COG2814	Major facilitator Superfamily
AKK42_RS10960	COG0582	viral genome integration into host DNA
AKK42_RS11020	COG0791	NLP P60 protein
AKK42_RS11025	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AKK42_RS11035	COG0346	lactoylglutathione lyase activity
AKK42_RS11040	COG1902	pentaerythritol trinitrate reductase activity
AKK42_RS11045	COG1309	transcriptional regulator
AKK42_RS11050	COG3313	Fe-S protein
AKK42_RS11055	COG4989	oxidoreductase activity
AKK42_RS11060	COG2032	superoxide dismutase activity
AKK42_RS11065	COG1289	transmembrane transporter activity
AKK42_RS11070	COG1566	PFAM secretion protein HlyD family protein
AKK42_RS11085	COG3706	GGDEF domain
AKK42_RS11100	COG3895	Periplasmic Protein
AKK42_RS11115	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AKK42_RS11120	COG0625	glutathione transferase activity
AKK42_RS11135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AKK42_RS11145	COG4659	FMN binding
AKK42_RS11180	COG2723	6-phospho-beta-galactosidase activity
AKK42_RS11185	COG0673	inositol 2-dehydrogenase activity
AKK42_RS11195	COG2814	Major facilitator Superfamily
AKK42_RS11215	COG3038	cytochrome b561
AKK42_RS11235	COG0583	DNA-binding transcription factor activity
AKK42_RS11240	COG3485	protocatechuate 3,4-dioxygenase
AKK42_RS11245	COG3485	protocatechuate 3,4-dioxygenase
AKK42_RS11250	COG5383	Protein conserved in bacteria
AKK42_RS11255	COG2272	Belongs to the type-B carboxylesterase lipase family
AKK42_RS11265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AKK42_RS11270	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AKK42_RS11275	COG1275	C4-dicarboxylate transporter malic acid transport protein
AKK42_RS11280	COG0500	methyltransferase
AKK42_RS11295	COG3708	Transcriptional regulator
AKK42_RS11295	COG2207	Transcriptional regulator
AKK42_RS11300	COG3135	benzoate transporter
AKK42_RS11305	COG1396	sequence-specific DNA binding
AKK42_RS11315	COG0826	peptidase U32
AKK42_RS11335	COG1294	oxidase, subunit
AKK42_RS11340	COG1271	oxidase subunit
AKK42_RS11345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AKK42_RS11350	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AKK42_RS11355	COG3842	ATPase activity
AKK42_RS11360	COG1176	ABC-type spermidine putrescine transport system, permease component I
AKK42_RS11365	COG1177	transmembrane transport
AKK42_RS11370	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS11405	COG0747	negative chemotaxis
AKK42_RS11415	COG3238	Protein conserved in bacteria
AKK42_RS11420	COG1247	-acetyltransferase
AKK42_RS11430	COG2130	NADP-dependent
AKK42_RS11445	COG3691	Protein conserved in bacteria
AKK42_RS11450	COG4772	TonB-dependent receptor
AKK42_RS11475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AKK42_RS11480	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AKK42_RS11485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AKK42_RS11490	COG1473	amidohydrolase
AKK42_RS11495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AKK42_RS11500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKK42_RS11510	COG0765	amino acid transport
AKK42_RS11515	COG1126	abc transporter atp-binding protein
AKK42_RS11525	COG0625	glutathione transferase activity
AKK42_RS11540	COG2211	Major facilitator Superfamily
AKK42_RS11555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AKK42_RS11560	COG3842	ATPase activity
AKK42_RS11565	COG1840	ABC-type Fe3 transport system, periplasmic component
AKK42_RS11570	COG1178	ABC-type Fe3 transport system permease component
AKK42_RS11575	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AKK42_RS11590	COG1414	Transcriptional regulator
AKK42_RS11595	COG4948	Mandelate Racemase Muconate Lactonizing
AKK42_RS11600	COG4829	muconolactone delta-isomerase
AKK42_RS11605	COG3485	protocatechuate 3,4-dioxygenase
AKK42_RS11635	COG3383	formate dehydrogenase (NAD+) activity
AKK42_RS11635	COG0243	molybdopterin cofactor binding
AKK42_RS11640	COG3383	formate dehydrogenase (NAD+) activity
AKK42_RS11640	COG0243	molybdopterin cofactor binding
AKK42_RS11645	COG0437	4 iron, 4 sulfur cluster binding
AKK42_RS11650	COG2864	formate dehydrogenase
AKK42_RS11660	COG2326	polyphosphate kinase activity
AKK42_RS11670	COG2814	Major facilitator Superfamily
AKK42_RS11680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AKK42_RS11690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AKK42_RS11700	COG0747	negative chemotaxis
AKK42_RS11705	COG1064	alcohol dehydrogenase
AKK42_RS11725	COG0488	(ABC) transporter
AKK42_RS11775	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS11780	COG3729	General stress protein
AKK42_RS11790	COG3685	Protein conserved in bacteria
AKK42_RS11800	COG0366	Alpha amylase catalytic
AKK42_RS11810	COG2323	membrane
AKK42_RS11820	COG3111	PFAM Bacterial OB fold (BOF) protein
AKK42_RS11830	COG1764	response to oxidative stress
AKK42_RS11850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AKK42_RS11855	COG3781	membrane
AKK42_RS11860	COG0243	molybdopterin cofactor binding
AKK42_RS11865	COG0583	DNA-binding transcription factor activity
AKK42_RS11870	COG2814	Major facilitator Superfamily
AKK42_RS11875	COG1285	pathogenesis
AKK42_RS11880	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AKK42_RS11900	COG0519	Catalyzes the synthesis of GMP from XMP
AKK42_RS11900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AKK42_RS11940	COG0596	Alpha beta hydrolase
AKK42_RS11950	COG2205	protein histidine kinase activity
AKK42_RS11960	COG0583	DNA-binding transcription factor activity
AKK42_RS11965	COG0076	glutamate decarboxylase activity
AKK42_RS11970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AKK42_RS11975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AKK42_RS11980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AKK42_RS11985	COG1116	anion transmembrane transporter activity
AKK42_RS11990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AKK42_RS12010	COG0673	inositol 2-dehydrogenase activity
AKK42_RS12020	COG1609	Transcriptional regulator
AKK42_RS12025	COG3706	GGDEF domain
AKK42_RS12035	COG0402	S-adenosylhomocysteine deaminase activity
AKK42_RS12040	COG1953	Uracil, thiamine, allantoin
AKK42_RS12085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AKK42_RS12100	COG2207	Transcriptional regulator
AKK42_RS12120	COG0583	DNA-binding transcription factor activity
AKK42_RS12135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AKK42_RS12200	COG0765	amino acid transport
AKK42_RS12210	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AKK42_RS12220	COG2070	2-Nitropropane dioxygenase
AKK42_RS12225	COG0583	DNA-binding transcription factor activity
AKK42_RS12235	COG1902	pentaerythritol trinitrate reductase activity
AKK42_RS12240	COG4529	Protein conserved in bacteria
AKK42_RS12245	COG0477	Major facilitator Superfamily
AKK42_RS12275	COG2223	nitrite transmembrane transporter activity
AKK42_RS12290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AKK42_RS12290	COG1116	anion transmembrane transporter activity
AKK42_RS12300	COG3665	Urea carboxylase-associated protein
AKK42_RS12305	COG0439	Biotin carboxylase
AKK42_RS12330	COG2197	response regulator
AKK42_RS12340	COG3539	Fimbrial protein
AKK42_RS12350	COG3121	Chaperone
AKK42_RS12375	COG0583	DNA-binding transcription factor activity
AKK42_RS12385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AKK42_RS12400	COG1172	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS12410	COG1609	Transcriptional regulator
AKK42_RS12440	COG0747	negative chemotaxis
AKK42_RS12445	COG0601	transmembrane transport
AKK42_RS12450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AKK42_RS12485	COG2186	Transcriptional regulator
AKK42_RS12505	COG2814	Major facilitator Superfamily
AKK42_RS12510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS12510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS12530	COG2819	hydrolase of the alpha beta superfamily
AKK42_RS12535	COG3300	MHYT domain
AKK42_RS12535	COG5001	Diguanylate cyclase
AKK42_RS12555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AKK42_RS12575	COG1649	PFAM Uncharacterised BCR, COG1649
AKK42_RS12580	COG3550	peptidyl-serine autophosphorylation
AKK42_RS12585	COG1396	sequence-specific DNA binding
AKK42_RS12590	COG2351	hydroxyisourate hydrolase activity
AKK42_RS12595	COG3648	Uricase
AKK42_RS12595	COG3195	allantoin biosynthetic process
AKK42_RS12600	COG2233	PERMEase
AKK42_RS12630	COG2207	Transcriptional regulator
AKK42_RS12645	COG4628	conserved protein (DUF2132)
AKK42_RS12665	COG2011	ABC-type metal ion transport system permease component
AKK42_RS12670	COG2070	2-Nitropropane dioxygenase
AKK42_RS12725	COG2199	diguanylate cyclase activity
AKK42_RS12740	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS12745	COG0583	DNA-binding transcription factor activity
AKK42_RS12755	COG0039	L-malate dehydrogenase activity
AKK42_RS12785	COG4977	sequence-specific DNA binding
AKK42_RS12795	COG0697	spore germination
AKK42_RS12800	COG2814	Major facilitator Superfamily
AKK42_RS12835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AKK42_RS12870	COG2223	nitrite transmembrane transporter activity
AKK42_RS12890	COG1349	DNA-binding transcription factor activity
AKK42_RS12895	COG2084	Dehydrogenase
AKK42_RS12900	COG3395	kinase activity
AKK42_RS12905	COG0235	Class ii aldolase
AKK42_RS12910	COG3622	Belongs to the hyi family
AKK42_RS12915	COG2610	gluconate transmembrane transporter activity
AKK42_RS12920	COG2207	Transcriptional regulator
AKK42_RS12920	COG3708	Transcriptional regulator
AKK42_RS12930	COG2200	EAL domain
AKK42_RS12935	COG1546	Belongs to the CinA family
AKK42_RS12940	COG0071	Belongs to the small heat shock protein (HSP20) family
AKK42_RS12950	COG2135	peptidase activity
AKK42_RS12955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AKK42_RS12975	COG4221	oxidoreductase activity
AKK42_RS12980	COG1802	Transcriptional regulator
AKK42_RS12990	COG0246	Mannitol dehydrogenase
AKK42_RS12995	COG2271	Major facilitator Superfamily
AKK42_RS13010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AKK42_RS13025	COG0243	molybdopterin cofactor binding
AKK42_RS13030	COG0437	4 iron, 4 sulfur cluster binding
AKK42_RS13035	COG3302	dmso reductase anchor subunit
AKK42_RS13050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AKK42_RS13055	COG1940	carbohydrate kinase activity
AKK42_RS13060	COG0583	DNA-binding transcription factor activity
AKK42_RS13065	COG2814	Major facilitator Superfamily
AKK42_RS13070	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AKK42_RS13085	COG3591	Belongs to the peptidase S1B family
AKK42_RS13105	COG0628	permease
AKK42_RS13135	COG0679	Auxin Efflux Carrier
AKK42_RS13145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AKK42_RS13170	COG3290	protein histidine kinase activity
AKK42_RS13175	COG4565	transcriptional regulatory protein
AKK42_RS13200	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AKK42_RS13200	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AKK42_RS13210	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AKK42_RS13215	COG0596	Alpha beta hydrolase
AKK42_RS13225	COG0183	Belongs to the thiolase family
AKK42_RS13230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AKK42_RS13240	COG1414	Transcriptional regulator
AKK42_RS13245	COG2840	Smr protein MutS2
AKK42_RS13250	COG0583	DNA-binding transcription factor activity
AKK42_RS13260	COG1473	amidohydrolase
AKK42_RS13265	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AKK42_RS13280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AKK42_RS13295	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AKK42_RS13300	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AKK42_RS13325	COG0531	amino acid
AKK42_RS13335	COG3136	membrane protein required for alginate biosynthesis
AKK42_RS13340	COG0745	RESPONSE REGULATOR receiver
AKK42_RS13350	COG2205	protein histidine kinase activity
AKK42_RS13360	COG0114	fumarate hydratase activity
AKK42_RS13365	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AKK42_RS13365	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AKK42_RS13370	COG1482	cell wall glycoprotein biosynthetic process
AKK42_RS13375	COG5339	Protein conserved in bacteria
AKK42_RS13380	COG1609	Transcriptional regulator
AKK42_RS13385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AKK42_RS13385	COG1263	PTS System
AKK42_RS13390	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AKK42_RS13420	COG0425	Belongs to the sulfur carrier protein TusA family
AKK42_RS13425	COG5562	phage envelope protein
AKK42_RS13430	COG0401	homolog of Blt101
AKK42_RS13435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AKK42_RS13440	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS13450	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AKK42_RS13455	COG0477	Major facilitator Superfamily
AKK42_RS13460	COG1113	amino acid transport
AKK42_RS13465	COG2988	succinylglutamate desuccinylase activity
AKK42_RS13470	COG3724	N-succinylarginine dihydrolase activity
AKK42_RS13475	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS13480	COG3138	arginine N-succinyltransferase
AKK42_RS13485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AKK42_RS13495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AKK42_RS13510	COG0183	Belongs to the thiolase family
AKK42_RS13520	COG0667	Aldo Keto reductase
AKK42_RS13525	COG2814	Major facilitator Superfamily
AKK42_RS13530	COG0667	Aldo Keto reductase
AKK42_RS13535	COG0583	DNA-binding transcription factor activity
AKK42_RS13560	COG4122	O-methyltransferase activity
AKK42_RS13570	COG1643	Atp-dependent helicase
AKK42_RS13585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AKK42_RS13590	COG3327	negative regulation of DNA-templated transcription, initiation
AKK42_RS13595	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AKK42_RS13600	COG0183	Belongs to the thiolase family
AKK42_RS13605	COG2050	protein possibly involved in aromatic compounds catabolism
AKK42_RS13610	COG1250	3-hydroxyacyl-CoA dehydrogenase
AKK42_RS13615	COG1024	Enoyl-CoA hydratase
AKK42_RS13620	COG1024	Enoyl-CoA hydratase
AKK42_RS13625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AKK42_RS13630	COG2151	metal-sulfur cluster biosynthetic enzyme
AKK42_RS13635	COG3396	Phenylacetate-CoA oxygenase
AKK42_RS13640	COG3460	Phenylacetate-CoA oxygenase
AKK42_RS13645	COG3396	Phenylacetate-CoA oxygenase
AKK42_RS13650	COG2030	dehydratase
AKK42_RS13650	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS13700	COG2072	flavoprotein involved in K transport
AKK42_RS13705	COG0583	DNA-binding transcription factor activity
AKK42_RS13710	COG1126	abc transporter atp-binding protein
AKK42_RS13720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKK42_RS13735	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS13740	COG2207	Transcriptional regulator
AKK42_RS13745	COG3784	Protein of unknown function (DUF1318)
AKK42_RS13755	COG2911	Protein conserved in bacteria
AKK42_RS13760	COG0586	Pfam SNARE associated Golgi protein
AKK42_RS13765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AKK42_RS13770	COG3187	Heat shock protein
AKK42_RS13775	COG3042	response to heat
AKK42_RS13780	COG0674	pyruvate-flavodoxin oxidoreductase activity
AKK42_RS13780	COG1013	pyruvate-flavodoxin oxidoreductase activity
AKK42_RS13780	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AKK42_RS13780	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AKK42_RS13785	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AKK42_RS13795	COG0589	response to stress
AKK42_RS13800	COG2135	peptidase activity
AKK42_RS13815	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AKK42_RS13820	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AKK42_RS13865	COG1196	nuclear chromosome segregation
AKK42_RS13945	COG3728	DNA packaging
AKK42_RS13945	COG5484	DNA packaging
AKK42_RS14020	COG4104	PAAR repeat-containing protein
AKK42_RS14050	COG1484	DNA-dependent DNA replication
AKK42_RS14085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AKK42_RS14115	COG0582	viral genome integration into host DNA
AKK42_RS14125	COG0513	Belongs to the DEAD box helicase family
AKK42_RS14135	COG1349	DNA-binding transcription factor activity
AKK42_RS14140	COG0673	inositol 2-dehydrogenase activity
AKK42_RS14155	COG1113	amino acid transport
AKK42_RS14160	COG1522	sequence-specific DNA binding
AKK42_RS14170	COG1448	Aminotransferase
AKK42_RS14175	COG2011	ABC-type metal ion transport system permease component
AKK42_RS14190	COG0436	Aminotransferase
AKK42_RS14215	COG0583	DNA-binding transcription factor activity
AKK42_RS14230	COG2207	Transcriptional regulator
AKK42_RS14235	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS14240	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS14250	COG0693	protein deglycase activity
AKK42_RS14255	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS14310	COG5002	protein histidine kinase activity
AKK42_RS14310	COG0784	Response regulator, receiver
AKK42_RS14310	COG2205	protein histidine kinase activity
AKK42_RS14315	COG3250	beta-galactosidase activity
AKK42_RS14320	COG0656	L-ascorbic acid biosynthetic process
AKK42_RS14340	COG4166	transmembrane transport
AKK42_RS14350	COG2866	Carboxypeptidase
AKK42_RS14355	COG4948	Mandelate Racemase Muconate Lactonizing
AKK42_RS14360	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AKK42_RS14365	COG3180	Ammonia monooxygenase
AKK42_RS14380	COG3106	COG3106 Predicted ATPase
AKK42_RS14390	COG1983	PspC domain protein
AKK42_RS14400	COG1842	Phage shock protein A
AKK42_RS14405	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AKK42_RS14415	COG1473	amidohydrolase
AKK42_RS14430	COG0702	epimerase
AKK42_RS14445	COG4171	peptide transport system, permease
AKK42_RS14460	COG2986	histidine ammonia-lyase
AKK42_RS14500	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AKK42_RS14500	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AKK42_RS14515	COG1349	DNA-binding transcription factor activity
AKK42_RS14530	COG0023	Translation Initiation Factor
AKK42_RS14540	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AKK42_RS14545	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AKK42_RS14550	COG0671	phosphoesterase, PA-phosphatase related
AKK42_RS14560	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AKK42_RS14595	COG0616	signal peptide processing
AKK42_RS14605	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS14610	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AKK42_RS14620	COG0583	DNA-binding transcription factor activity
AKK42_RS14630	COG0009	L-threonylcarbamoyladenylate synthase
AKK42_RS14640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AKK42_RS14645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AKK42_RS14645	COG0512	Glutamine amidotransferase of anthranilate synthase
AKK42_RS14650	COG0135	phosphoribosylanthranilate isomerase activity
AKK42_RS14650	COG0134	indole-3-glycerol-phosphate synthase activity
AKK42_RS14680	COG4774	siderophore transport
AKK42_RS14690	COG3047	cAMP biosynthetic process
AKK42_RS14695	COG0727	PFAM Uncharacterised protein family (UPF0153)
AKK42_RS14725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AKK42_RS14730	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS14735	COG1988	membrane-bound metal-dependent
AKK42_RS14740	COG1823	symporter activity
AKK42_RS14750	COG0753	catalase activity
AKK42_RS14760	COG1486	melibiose metabolic process
AKK42_RS14765	COG1917	Cupin 2, conserved barrel domain protein
AKK42_RS14765	COG2169	Transcriptional regulator
AKK42_RS14770	COG1447	Phosphotransferase system cellobiose-specific component IIA
AKK42_RS14775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AKK42_RS14785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AKK42_RS14790	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AKK42_RS14800	COG0322	excinuclease ABC activity
AKK42_RS14805	COG3678	ATP-independent chaperone mediated protein folding
AKK42_RS14820	COG3724	N-succinylarginine dihydrolase activity
AKK42_RS14830	COG3138	arginine N-succinyltransferase
AKK42_RS14840	COG0708	Exodeoxyribonuclease III
AKK42_RS14845	COG0398	Pfam SNARE associated Golgi protein
AKK42_RS14850	COG0398	Pfam SNARE associated Golgi protein
AKK42_RS14855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AKK42_RS14860	COG4134	Bacterial extracellular solute-binding protein
AKK42_RS14865	COG4135	transport system, permease component
AKK42_RS14870	COG4136	ATPase activity
AKK42_RS14875	COG2897	thiosulfate sulfurtransferase activity
AKK42_RS14880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AKK42_RS14885	COG0494	nUDIX hydrolase
AKK42_RS14895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AKK42_RS14900	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS14900	COG3321	synthase
AKK42_RS14900	COG0604	alcohol dehydrogenase
AKK42_RS14905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AKK42_RS14910	COG0709	Synthesizes selenophosphate from selenide and ATP
AKK42_RS14920	COG0778	Nitroreductase
AKK42_RS14925	COG0616	signal peptide processing
AKK42_RS14930	COG0252	asparaginase activity
AKK42_RS14935	COG1335	isochorismatase
AKK42_RS14940	COG2814	Major facilitator Superfamily
AKK42_RS14945	COG1349	DNA-binding transcription factor activity
AKK42_RS14950	COG0667	Aldo Keto reductase
AKK42_RS14955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AKK42_RS14960	COG0191	fructose-bisphosphate aldolase activity
AKK42_RS14965	COG1063	alcohol dehydrogenase
AKK42_RS14970	COG2271	Major facilitator Superfamily
AKK42_RS14975	COG1063	alcohol dehydrogenase
AKK42_RS14990	COG3139	Protein of unknown function (DUF1315)
AKK42_RS15010	COG0656	L-ascorbic acid biosynthetic process
AKK42_RS15015	COG3713	MltA-interacting MipA family protein
AKK42_RS15020	COG2766	serine protein kinase
AKK42_RS15030	COG0386	Belongs to the glutathione peroxidase family
AKK42_RS15065	COG1126	abc transporter atp-binding protein
AKK42_RS15070	COG0765	amino acid transport
AKK42_RS15075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKK42_RS15085	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AKK42_RS15095	COG0583	DNA-binding transcription factor activity
AKK42_RS15100	COG1902	pentaerythritol trinitrate reductase activity
AKK42_RS15110	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS15115	COG0583	DNA-binding transcription factor activity
AKK42_RS15120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AKK42_RS15135	COG0859	PFAM glycosyl transferase family 9
AKK42_RS15140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AKK42_RS15150	COG2207	Transcriptional regulator
AKK42_RS15155	COG2807	transmembrane transport
AKK42_RS15160	COG0504	CTP synthase activity
AKK42_RS15165	COG1683	Conserved Protein
AKK42_RS15170	COG3189	MarR family transcriptional regulator
AKK42_RS15175	COG3042	response to heat
AKK42_RS15180	COG2199	diguanylate cyclase activity
AKK42_RS15180	COG2203	Gaf domain
AKK42_RS15195	COG3182	Iron-regulated membrane protein
AKK42_RS15205	COG1560	Kdo2-lipid A biosynthetic process
AKK42_RS15220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AKK42_RS15225	COG3706	GGDEF domain
AKK42_RS15230	COG0583	DNA-binding transcription factor activity
AKK42_RS15235	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AKK42_RS15245	COG2200	EAL domain
AKK42_RS15245	COG2771	luxR family
AKK42_RS15265	COG1294	oxidase, subunit
AKK42_RS15270	COG1271	oxidase subunit
AKK42_RS15275	COG3546	catalase activity
AKK42_RS15280	COG3685	Protein conserved in bacteria
AKK42_RS15285	COG3685	Protein conserved in bacteria
AKK42_RS15290	COG3729	General stress protein
AKK42_RS15300	COG1063	alcohol dehydrogenase
AKK42_RS15305	COG3813	Protein conserved in bacteria
AKK42_RS15345	COG0538	isocitrate dehydrogenase activity
AKK42_RS15350	COG1187	pseudouridine synthase activity
AKK42_RS15370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AKK42_RS15390	COG2205	protein histidine kinase activity
AKK42_RS15395	COG2850	peptidyl-arginine hydroxylation
AKK42_RS15415	COG1177	transmembrane transport
AKK42_RS15430	COG0318	PFAM AMP-dependent synthetase and ligase
AKK42_RS15440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AKK42_RS15450	COG4591	ABC-type transport system involved in lipoprotein release permease component
AKK42_RS15460	COG4591	ABC-type transport system involved in lipoprotein release permease component
AKK42_RS15470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AKK42_RS15475	COG1376	ErfK ybiS ycfS ynhG family protein
AKK42_RS15475	COG1388	LysM domain
AKK42_RS15490	COG1309	transcriptional regulator
AKK42_RS15505	COG3134	Outer membrane lipoprotein
AKK42_RS15510	COG1252	NADH dehydrogenase
AKK42_RS15535	COG5633	Lipoprotein
AKK42_RS15540	COG0537	adenosine 5'-monophosphoramidase activity
AKK42_RS15550	COG0084	hydrolase, TatD family'
AKK42_RS15555	COG0470	DNA polymerase III
AKK42_RS15565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AKK42_RS15570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AKK42_RS15575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AKK42_RS15590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AKK42_RS15610	COG1399	metal-binding, possibly nucleic acid-binding protein
AKK42_RS15625	COG1530	ribonuclease E activity
AKK42_RS15630	COG0583	DNA-binding transcription factor activity
AKK42_RS15635	COG2814	Major facilitator Superfamily
AKK42_RS15640	COG0728	peptidoglycan biosynthetic process
AKK42_RS15655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AKK42_RS15705	COG1560	Kdo2-lipid A biosynthetic process
AKK42_RS15720	COG5645	(Lipo)protein
AKK42_RS15755	COG3381	protein complex oligomerization
AKK42_RS15775	COG0583	DNA-binding transcription factor activity
AKK42_RS15785	COG1335	isochorismatase
AKK42_RS15795	COG1702	phosphate starvation-inducible protein PhoH
AKK42_RS15815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AKK42_RS15825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AKK42_RS15840	COG1309	transcriptional regulator
AKK42_RS15875	COG2233	PERMEase
AKK42_RS15885	COG3729	General stress protein
AKK42_RS15915	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS15930	COG0531	amino acid
AKK42_RS15935	COG0174	glutamine synthetase
AKK42_RS15940	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AKK42_RS15945	COG1396	sequence-specific DNA binding
AKK42_RS15945	COG1917	Cupin 2, conserved barrel domain protein
AKK42_RS15950	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS15955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AKK42_RS15960	COG0583	DNA-binding transcription factor activity
AKK42_RS15965	COG0473	3-isopropylmalate dehydrogenase activity
AKK42_RS15970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AKK42_RS15975	COG4638	Rieske (2fe-2S)
AKK42_RS15980	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS15985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AKK42_RS15990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AKK42_RS15990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS15990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS15995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AKK42_RS16000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AKK42_RS16005	COG1882	Formate acetyltransferase
AKK42_RS16010	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AKK42_RS16015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AKK42_RS16025	COG2207	Transcriptional regulator
AKK42_RS16030	COG3706	GGDEF domain
AKK42_RS16050	COG2200	EAL domain
AKK42_RS16060	COG0058	SHG alpha-glucan phosphorylase activity
AKK42_RS16075	COG0670	Belongs to the BI1 family
AKK42_RS16090	COG2207	Transcriptional regulator
AKK42_RS16095	COG1881	PFAM PEBP family protein
AKK42_RS16110	COG1832	CoA-binding protein
AKK42_RS16120	COG0210	DNA helicase
AKK42_RS16125	COG3304	Inner membrane component domain
AKK42_RS16130	COG1289	transmembrane transporter activity
AKK42_RS16135	COG3070	regulator of competence-specific genes
AKK42_RS16155	COG1067	ATP-dependent peptidase activity
AKK42_RS16165	COG3130	regulation of translation
AKK42_RS16175	COG3009	Protein conserved in bacteria
AKK42_RS16180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AKK42_RS16180	COG3008	intermembrane lipid transfer
AKK42_RS16185	COG2995	paraquat-inducible protein a
AKK42_RS16190	COG0488	(ABC) transporter
AKK42_RS16200	COG0633	Ferredoxin
AKK42_RS16200	COG3217	Mosc domain protein beta barrel domain protein
AKK42_RS16215	COG0431	NADPH-dependent FMN reductase
AKK42_RS16220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AKK42_RS16225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AKK42_RS16230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AKK42_RS16240	COG0308	aminopeptidase N
AKK42_RS16250	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AKK42_RS16260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AKK42_RS16265	COG1448	Aminotransferase
AKK42_RS16270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AKK42_RS16275	COG3108	Peptidase M15
AKK42_RS16280	COG2989	Protein conserved in bacteria
AKK42_RS16290	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AKK42_RS16300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AKK42_RS16305	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AKK42_RS16310	COG3173	Aminoglycoside phosphotransferase
AKK42_RS16325	COG3214	Protein conserved in bacteria
AKK42_RS16340	COG0658	competence protein
AKK42_RS16340	COG2333	competence protein COMEC
AKK42_RS16350	COG0539	negative regulation of cytoplasmic translation
AKK42_RS16370	COG2323	membrane
AKK42_RS16375	COG1944	ATP diphosphatase activity
AKK42_RS16380	COG2116	formate transmembrane transporter activity
AKK42_RS16385	COG1882	Formate acetyltransferase
AKK42_RS16390	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AKK42_RS16395	COG0477	Major facilitator Superfamily
AKK42_RS16405	COG3302	dmso reductase anchor subunit
AKK42_RS16410	COG0437	4 iron, 4 sulfur cluster binding
AKK42_RS16415	COG0243	molybdopterin cofactor binding
AKK42_RS16425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AKK42_RS16435	COG1674	ftsk spoiiie
AKK42_RS16435	COG1178	ABC-type Fe3 transport system permease component
AKK42_RS16445	COG0492	ferredoxin-NADP+ reductase activity
AKK42_RS16450	COG4988	ABC transporter
AKK42_RS16455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AKK42_RS16470	COG0542	response to heat
AKK42_RS16480	COG1278	Cold shock
AKK42_RS16490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKK42_RS16495	COG3593	DNA synthesis involved in DNA repair
AKK42_RS16505	COG2431	L-lysine efflux transmembrane transporter activity
AKK42_RS16515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AKK42_RS16525	COG0028	Belongs to the TPP enzyme family
AKK42_RS16530	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AKK42_RS16535	COG0702	epimerase
AKK42_RS16540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AKK42_RS16545	COG3023	N-Acetylmuramoyl-L-alanine amidase
AKK42_RS16550	COG2203	Gaf domain
AKK42_RS16550	COG3706	GGDEF domain
AKK42_RS16550	COG4251	negative regulation of phosphorylation
AKK42_RS16550	COG5001	Diguanylate cyclase
AKK42_RS16565	COG1126	abc transporter atp-binding protein
AKK42_RS16570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKK42_RS16575	COG4215	(ABC) transporter
AKK42_RS16580	COG4160	amino acid transport
AKK42_RS16585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKK42_RS16590	COG5002	protein histidine kinase activity
AKK42_RS16595	COG0745	RESPONSE REGULATOR receiver
AKK42_RS16610	COG1177	transmembrane transport
AKK42_RS16615	COG1176	ABC-type spermidine putrescine transport system, permease component I
AKK42_RS16620	COG3842	ATPase activity
AKK42_RS16625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AKK42_RS16670	COG3226	Transcriptional regulator
AKK42_RS16675	COG0738	Major facilitator superfamily
AKK42_RS16680	COG0561	phosphatase activity
AKK42_RS16685	COG2814	Major facilitator Superfamily
AKK42_RS16690	COG0671	phosphoesterase, PA-phosphatase related
AKK42_RS16695	COG1349	DNA-binding transcription factor activity
AKK42_RS16700	COG1686	Belongs to the peptidase S11 family
AKK42_RS16705	COG0625	glutathione transferase activity
AKK42_RS16710	COG2133	pyrroloquinoline quinone binding
AKK42_RS16750	COG1446	asparaginase
AKK42_RS16755	COG0303	'Molybdopterin
AKK42_RS16760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AKK42_RS16765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AKK42_RS16770	COG1882	Formate acetyltransferase
AKK42_RS16775	COG0561	phosphatase activity
AKK42_RS16785	COG1609	Transcriptional regulator
AKK42_RS16790	COG2271	Major facilitator Superfamily
AKK42_RS16800	COG0488	(ABC) transporter
AKK42_RS16810	COG1376	ErfK ybiS ycfS ynhG family protein
AKK42_RS16815	COG2188	Transcriptional regulator
AKK42_RS16820	COG2723	6-phospho-beta-galactosidase activity
AKK42_RS16825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AKK42_RS16830	COG1321	iron dependent repressor
AKK42_RS16840	COG2194	sulfuric ester hydrolase activity
AKK42_RS16845	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AKK42_RS16865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKK42_RS16870	COG0765	amino acid transport
AKK42_RS16875	COG1126	abc transporter atp-binding protein
AKK42_RS16880	COG0668	transmembrane transport
AKK42_RS16890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AKK42_RS16900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AKK42_RS16910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AKK42_RS16920	COG0513	Belongs to the DEAD box helicase family
AKK42_RS16925	COG3958	Transketolase
AKK42_RS16930	COG3959	Transketolase, thiamine diphosphate binding domain
AKK42_RS16935	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS16940	COG2271	Major facilitator Superfamily
AKK42_RS16950	COG0583	DNA-binding transcription factor activity
AKK42_RS16955	COG1309	transcriptional regulator
AKK42_RS16960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKK42_RS16965	COG1131	(ABC) transporter
AKK42_RS16970	COG0842	Transport permease protein
AKK42_RS16975	COG0842	Transport permease protein
AKK42_RS16985	COG3568	Endonuclease Exonuclease Phosphatase
AKK42_RS16990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AKK42_RS16995	COG0392	lysyltransferase activity
AKK42_RS17000	COG0670	Belongs to the BI1 family
AKK42_RS17005	COG0314	molybdopterin synthase activity
AKK42_RS17010	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AKK42_RS17020	COG0521	Mo-molybdopterin cofactor biosynthetic process
AKK42_RS17040	COG0745	RESPONSE REGULATOR receiver
AKK42_RS17045	COG0642	Histidine kinase
AKK42_RS17070	COG2226	methyltransferase
AKK42_RS17085	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AKK42_RS17090	COG1881	PFAM PEBP family protein
AKK42_RS17125	COG4677	pectinesterase activity
AKK42_RS17135	COG0589	response to stress
AKK42_RS17140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKK42_RS17175	COG0789	Transcriptional regulator
AKK42_RS17180	COG2200	EAL domain
AKK42_RS17205	COG0561	phosphatase activity
AKK42_RS17210	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AKK42_RS17215	COG4149	molybdate abc transporter
AKK42_RS17220	COG0725	ABC transporter, periplasmic molybdate-binding protein
AKK42_RS17230	COG2005	Transcriptional regulator
AKK42_RS17230	COG3585	molybdate ion transport
AKK42_RS17235	COG1119	ATPase activity
AKK42_RS17250	COG1085	galactose-1-phosphate uridylyltransferase
AKK42_RS17260	COG2017	converts alpha-aldose to the beta-anomer
AKK42_RS17270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AKK42_RS17285	COG3201	nicotinamide mononucleotide transporter
AKK42_RS17290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AKK42_RS17330	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AKK42_RS17335	COG2885	chlorophyll binding
AKK42_RS17345	COG3064	Membrane
AKK42_RS17345	COG3064	Membrane
AKK42_RS17350	COG0848	biopolymer transport protein
AKK42_RS17355	COG0811	peptide transport
AKK42_RS17360	COG0824	Thioesterase
AKK42_RS17365	COG3790	cyd operon protein YbgE
AKK42_RS17370	COG4890	Cyd operon protein YbgT
AKK42_RS17375	COG1294	oxidase, subunit
AKK42_RS17380	COG1271	oxidase subunit
AKK42_RS17385	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AKK42_RS17395	COG0508	dehydrogenase complex catalyzes the overall conversion of
AKK42_RS17400	COG0567	Dehydrogenase, E1 component
AKK42_RS17405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AKK42_RS17410	COG1053	succinate dehydrogenase
AKK42_RS17415	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AKK42_RS17420	COG2009	succinate dehydrogenase
AKK42_RS17425	COG0372	Belongs to the citrate synthase family
AKK42_RS17450	COG1984	allophanate hydrolase subunit 2
AKK42_RS17455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AKK42_RS17495	COG2205	protein histidine kinase activity
AKK42_RS17500	COG0745	RESPONSE REGULATOR receiver
AKK42_RS17510	COG0033	Phosphoglucomutase
AKK42_RS17525	COG0596	Alpha beta hydrolase
AKK42_RS17540	COG0735	belongs to the Fur family
AKK42_RS17545	COG0583	DNA-binding transcription factor activity
AKK42_RS17550	COG1053	succinate dehydrogenase
AKK42_RS17595	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AKK42_RS17600	COG1940	carbohydrate kinase activity
AKK42_RS17600	COG1846	Transcriptional regulator
AKK42_RS17605	COG0647	UMP catabolic process
AKK42_RS17610	COG0367	asparagine synthase
AKK42_RS17650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AKK42_RS17660	COG1702	phosphate starvation-inducible protein PhoH
AKK42_RS17685	COG0765	amino acid transport
AKK42_RS17690	COG0765	amino acid transport
AKK42_RS17695	COG1126	abc transporter atp-binding protein
AKK42_RS17700	COG2831	hemolysin activation secretion protein
AKK42_RS17710	COG2888	peptidyl-tyrosine sulfation
AKK42_RS17725	COG1466	dna polymerase III delta subunit
AKK42_RS17740	COG0799	negative regulation of ribosome biogenesis
AKK42_RS17750	COG0768	penicillin binding
AKK42_RS17755	COG0772	Belongs to the SEDS family
AKK42_RS17760	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AKK42_RS17765	COG1686	Belongs to the peptidase S11 family
AKK42_RS17780	COG0583	DNA-binding transcription factor activity
AKK42_RS17790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AKK42_RS17795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AKK42_RS17815	COG3069	C4-dicarboxylate transmembrane transporter activity
AKK42_RS17820	COG3719	Belongs to the RNase T2 family
AKK42_RS17825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AKK42_RS17845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AKK42_RS17850	COG0583	DNA-binding transcription factor activity
AKK42_RS17855	COG3969	phosphoadenosine phosphosulfate
AKK42_RS17860	COG1475	DNA binding
AKK42_RS17865	COG0436	Aminotransferase
AKK42_RS17890	COG1129	ABC transporter
AKK42_RS17895	COG1172	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS17900	COG1172	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS17910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AKK42_RS17925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AKK42_RS17935	COG0402	S-adenosylhomocysteine deaminase activity
AKK42_RS17945	COG0483	inositol monophosphate 1-phosphatase activity
AKK42_RS17950	COG2271	Major facilitator Superfamily
AKK42_RS17980	COG1172	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS17985	COG1129	ABC transporter
AKK42_RS17990	COG0371	Dehydrogenase
AKK42_RS18010	COG2879	small protein
AKK42_RS18015	COG1966	Carbon starvation protein
AKK42_RS18025	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS18030	COG1535	isochorismatase
AKK42_RS18030	COG3433	isochorismatase activity
AKK42_RS18035	COG1021	2,3-dihydroxybenzoate-AMP ligase
AKK42_RS18040	COG1169	isochorismate synthase
AKK42_RS18045	COG4592	Periplasmic binding protein
AKK42_RS18055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKK42_RS18060	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKK42_RS18065	COG1120	ATPase activity
AKK42_RS18070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AKK42_RS18070	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AKK42_RS18075	COG3251	PFAM MbtH domain protein
AKK42_RS18080	COG2382	esterase
AKK42_RS18085	COG4771	TonB-dependent receptor
AKK42_RS18090	COG2977	Belongs to the P-Pant transferase superfamily
AKK42_RS18095	COG3958	Transketolase
AKK42_RS18100	COG3959	Transketolase, thiamine diphosphate binding domain
AKK42_RS18105	COG2390	Transcriptional regulator
AKK42_RS18110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AKK42_RS18115	COG1879	ABC-type sugar transport system periplasmic component
AKK42_RS18125	COG1129	ABC transporter
AKK42_RS18130	COG1172	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS18140	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS18155	COG0583	DNA-binding transcription factor activity
AKK42_RS18160	COG0668	transmembrane transport
AKK42_RS18170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AKK42_RS18215	COG0747	negative chemotaxis
AKK42_RS18220	COG0601	transmembrane transport
AKK42_RS18225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AKK42_RS18230	COG0444	Belongs to the ABC transporter superfamily
AKK42_RS18235	COG4608	Belongs to the ABC transporter superfamily
AKK42_RS18245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AKK42_RS18250	COG4221	oxidoreductase activity
AKK42_RS18260	COG4215	(ABC) transporter
AKK42_RS18265	COG0765	amino acid transport
AKK42_RS18270	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AKK42_RS18280	COG0436	Aminotransferase
AKK42_RS18285	COG0697	spore germination
AKK42_RS18300	COG4608	Belongs to the ABC transporter superfamily
AKK42_RS18305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AKK42_RS18325	COG3698	Phosphodiester glycosidase
AKK42_RS18370	COG2315	Protein conserved in bacteria
AKK42_RS18375	COG0778	Nitroreductase
AKK42_RS18385	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AKK42_RS18395	COG3716	PTS system mannose fructose sorbose family IID component
AKK42_RS18400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AKK42_RS18405	COG2222	sugar isomerase
AKK42_RS18410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AKK42_RS18410	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AKK42_RS18425	COG0477	Major facilitator Superfamily
AKK42_RS18430	COG0668	transmembrane transport
AKK42_RS18435	COG1609	Transcriptional regulator
AKK42_RS18455	COG2211	Major facilitator Superfamily
AKK42_RS18460	COG1113	amino acid transport
AKK42_RS18475	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS18480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AKK42_RS18490	COG0531	amino acid
AKK42_RS18535	COG0667	Aldo Keto reductase
AKK42_RS18540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKK42_RS18545	COG1473	amidohydrolase
AKK42_RS18575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKK42_RS18580	COG1120	ATPase activity
AKK42_RS18585	COG1566	PFAM secretion protein HlyD family protein
AKK42_RS18640	COG4211	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS18645	COG1129	ABC transporter
AKK42_RS18660	COG0673	inositol 2-dehydrogenase activity
AKK42_RS18695	COG3104	oligopeptide transport
AKK42_RS18700	COG1982	Orn Lys Arg decarboxylase major
AKK42_RS18705	COG0531	amino acid
AKK42_RS18710	COG3710	Transcriptional regulator
AKK42_RS18720	COG1560	Kdo2-lipid A biosynthetic process
AKK42_RS18765	COG2501	S4 domain
AKK42_RS18775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AKK42_RS18790	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AKK42_RS18795	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AKK42_RS18815	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AKK42_RS18820	COG4181	ATPase activity
AKK42_RS18825	COG2755	lipolytic protein G-D-S-L family
AKK42_RS18830	COG0300	oxidoreductase activity
AKK42_RS18835	COG3118	belongs to the thioredoxin family
AKK42_RS18840	COG0390	transport system, permease component
AKK42_RS18845	COG4619	ABC transporter
AKK42_RS18850	COG0330	HflC and HflK could
AKK42_RS18855	COG1585	Membrane protein implicated in regulation of membrane protease activity
AKK42_RS18870	COG3735	TraB family
AKK42_RS18875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AKK42_RS18885	COG2223	nitrite transmembrane transporter activity
AKK42_RS18900	COG4651	solute:proton antiporter activity
AKK42_RS18900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AKK42_RS18905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AKK42_RS18945	COG2832	Protein of unknown function (DUF454)
AKK42_RS18950	COG3923	Primosomal replication protein n
AKK42_RS18965	COG1196	nuclear chromosome segregation
AKK42_RS18965	COG3264	Mechanosensitive ion channel
AKK42_RS18970	COG1309	transcriptional regulator
AKK42_RS18975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKK42_RS18980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AKK42_RS18995	COG0110	maltose O-acetyltransferase activity
AKK42_RS19045	COG1874	Beta-galactosidase
AKK42_RS19050	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AKK42_RS19055	COG3833	ABC-type maltose transport systems, permease component
AKK42_RS19060	COG1175	transmembrane transport
AKK42_RS19065	COG2182	Extracellular solute-binding protein
AKK42_RS19080	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AKK42_RS19095	COG2364	Membrane
AKK42_RS19120	COG3695	enzyme binding
AKK42_RS19125	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AKK42_RS19130	COG1946	Acyl-CoA thioesterase
AKK42_RS19135	COG0004	ammonium transporteR
AKK42_RS19140	COG0347	Belongs to the P(II) protein family
AKK42_RS19145	COG1132	(ABC) transporter
AKK42_RS19150	COG1132	(ABC) transporter
AKK42_RS19155	COG1522	sequence-specific DNA binding
AKK42_RS19170	COG4533	DNA binding
AKK42_RS19180	COG0824	Thioesterase
AKK42_RS19185	COG1555	photosystem II stabilization
AKK42_RS19190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AKK42_RS19195	COG0776	regulation of translation
AKK42_RS19200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AKK42_RS19220	COG0271	Belongs to the BolA IbaG family
AKK42_RS19225	COG3056	Lipoprotein
AKK42_RS19230	COG2223	nitrite transmembrane transporter activity
AKK42_RS19235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AKK42_RS19240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AKK42_RS19245	COG1845	cytochrome c oxidase, subunit III
AKK42_RS19250	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AKK42_RS19265	COG1414	Transcriptional regulator
AKK42_RS19270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AKK42_RS19275	COG1053	succinate dehydrogenase
AKK42_RS19285	COG1053	succinate dehydrogenase
AKK42_RS19300	COG0673	inositol 2-dehydrogenase activity
AKK42_RS19305	COG2814	Major facilitator Superfamily
AKK42_RS19315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AKK42_RS19340	COG0142	geranyltranstransferase activity
AKK42_RS19350	COG0667	Aldo Keto reductase
AKK42_RS19355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AKK42_RS19375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AKK42_RS19375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AKK42_RS19385	COG4238	major outer membrane lipoprotein
AKK42_RS19405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AKK42_RS19410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AKK42_RS19415	COG1862	Preprotein translocase
AKK42_RS19440	COG0450	alkyl hydroperoxide reductase
AKK42_RS19450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS19465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AKK42_RS19475	COG1228	amidohydrolase
AKK42_RS19485	COG1335	isochorismatase
AKK42_RS19490	COG0583	DNA-binding transcription factor activity
AKK42_RS19495	COG0366	Alpha amylase catalytic
AKK42_RS19520	COG0420	3'-5' exonuclease activity
AKK42_RS19525	COG0419	ATPase involved in DNA repair
AKK42_RS19530	COG1940	carbohydrate kinase activity
AKK42_RS19545	COG4126	flavin adenine dinucleotide binding
AKK42_RS19555	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AKK42_RS19560	COG3416	Protein conserved in bacteria
AKK42_RS19570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AKK42_RS19580	COG1785	Belongs to the alkaline phosphatase family
AKK42_RS19600	COG1181	Belongs to the D-alanine--D-alanine ligase family
AKK42_RS19620	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AKK42_RS19625	COG1335	isochorismatase
AKK42_RS19630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AKK42_RS19635	COG0113	porphobilinogen synthase activity
AKK42_RS19645	COG2175	clavaminate synthase activity
AKK42_RS19650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AKK42_RS19655	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AKK42_RS19660	COG4521	taurine ABC transporter
AKK42_RS19665	COG2040	homocysteine
AKK42_RS19670	COG0833	amino acid
AKK42_RS19685	COG4303	Ethanolamine ammonia lyase large subunit
AKK42_RS19690	COG4302	ethanolamine ammonia-lyase activity
AKK42_RS19730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKK42_RS19735	COG1126	abc transporter atp-binding protein
AKK42_RS19740	COG0765	amino acid transport
AKK42_RS19745	COG0765	amino acid transport
AKK42_RS19760	COG3188	usher protein
AKK42_RS19785	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AKK42_RS19795	COG3639	organic phosphonate transmembrane transporter activity
AKK42_RS19810	COG0791	NLP P60 protein
AKK42_RS19840	COG0582	viral genome integration into host DNA
AKK42_RS19895	COG2963	transposase activity
AKK42_RS19940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AKK42_RS19945	COG0022	dehydrogenase e1 component
AKK42_RS19950	COG0508	dehydrogenase complex catalyzes the overall conversion of
AKK42_RS19955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AKK42_RS19975	COG1070	Carbohydrate kinase
AKK42_RS19980	COG1028	Short-chain dehydrogenase reductase Sdr
AKK42_RS19985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AKK42_RS19990	COG3775	system Galactitol-specific IIC component
AKK42_RS19995	COG0625	glutathione transferase activity
AKK42_RS20000	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AKK42_RS20015	COG0579	oxidoreductase
AKK42_RS20020	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS20025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AKK42_RS20030	COG1113	amino acid transport
AKK42_RS20035	COG1802	Transcriptional regulator
AKK42_RS20055	COG2195	Cleaves the N-terminal amino acid of tripeptides
AKK42_RS20060	COG0454	-acetyltransferase
AKK42_RS20075	COG2991	Protein conserved in bacteria
AKK42_RS20090	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AKK42_RS20095	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AKK42_RS20115	COG3034	peptidoglycan biosynthetic process
AKK42_RS20120	COG0121	glutamine amidotransferase
AKK42_RS20130	COG1960	acyl-CoA dehydrogenase activity
AKK42_RS20135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AKK42_RS20150	COG0583	DNA-binding transcription factor activity
AKK42_RS20170	COG2226	methyltransferase
AKK42_RS20180	COG1388	LysM domain
AKK42_RS20180	COG0741	lytic transglycosylase activity
AKK42_RS20185	COG2226	methyltransferase
AKK42_RS20195	COG2814	Major facilitator Superfamily
AKK42_RS20200	COG0583	DNA-binding transcription factor activity
AKK42_RS20205	COG0656	L-ascorbic acid biosynthetic process
AKK42_RS20230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AKK42_RS20240	COG2011	ABC-type metal ion transport system permease component
AKK42_RS20245	COG1464	Belongs to the NlpA lipoprotein family
AKK42_RS20255	COG1720	tRNA m6t6A37 methyltransferase activity
AKK42_RS20265	COG0791	NLP P60 protein
AKK42_RS20270	COG3015	lipoprotein NlpE involved in copper resistance
AKK42_RS20275	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AKK42_RS20290	COG4568	rho-dependent transcription termination
AKK42_RS20300	COG0346	lactoylglutathione lyase activity
AKK42_RS20305	COG1982	Orn Lys Arg decarboxylase major
AKK42_RS20315	COG0587	DNA-directed DNA polymerase activity
AKK42_RS20345	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AKK42_RS20355	COG0750	zinc metalloprotease
AKK42_RS20360	COG0575	Belongs to the CDS family
AKK42_RS20395	COG0024	Methionine aminopeptidase
AKK42_RS20400	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AKK42_RS20415	COG3835	regulator
AKK42_RS20420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKK42_RS20440	COG2860	membrane
AKK42_RS20460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKK42_RS20465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AKK42_RS20470	COG1120	ATPase activity
AKK42_RS20475	COG4774	siderophore transport
AKK42_RS20480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AKK42_RS20575	COG1643	Atp-dependent helicase
AKK42_RS20580	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AKK42_RS20600	COG0617	tRNA 3'-terminal CCA addition
AKK42_RS20605	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AKK42_RS20625	COG0726	polysaccharide deacetylase
AKK42_RS20630	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS20635	COG0842	Transport permease protein
AKK42_RS20640	COG1131	(ABC) transporter
AKK42_RS20645	COG0288	reversible hydration of carbon dioxide
AKK42_RS20660	COG4993	Dehydrogenase
AKK42_RS20665	COG2132	Multicopper oxidase
AKK42_RS20710	COG3064	Membrane
AKK42_RS20725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AKK42_RS20730	COG0508	dehydrogenase complex catalyzes the overall conversion of
AKK42_RS20735	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AKK42_RS20740	COG2186	Transcriptional regulator
AKK42_RS20750	COG1113	amino acid transport
AKK42_RS20755	COG2211	Major facilitator Superfamily
AKK42_RS20760	COG3940	Belongs to the glycosyl hydrolase 43 family
AKK42_RS20765	COG3725	Membrane protein required for beta-lactamase induction
AKK42_RS20780	COG4969	Belongs to the N-Me-Phe pilin family
AKK42_RS20785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AKK42_RS20790	COG1459	type II secretion system
AKK42_RS20820	COG0494	nUDIX hydrolase
AKK42_RS20840	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AKK42_RS20845	COG0849	cell division
AKK42_RS20870	COG0772	Belongs to the SEDS family
AKK42_RS20885	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AKK42_RS20895	COG0768	penicillin binding
AKK42_RS20915	COG1609	Transcriptional regulator
AKK42_RS20925	COG0028	Belongs to the TPP enzyme family
AKK42_RS20965	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AKK42_RS20970	COG0738	Major facilitator superfamily
AKK42_RS20980	COG0583	DNA-binding transcription factor activity
AKK42_RS20985	COG2271	Major facilitator Superfamily
AKK42_RS20990	COG2814	Major facilitator Superfamily
AKK42_RS21015	COG1178	ABC-type Fe3 transport system permease component
AKK42_RS21025	COG0586	Pfam SNARE associated Golgi protein
AKK42_RS21050	COG0417	DNA replication proofreading
AKK42_RS21060	COG0564	pseudouridine synthase activity
AKK42_RS21075	COG3493	citrate carrier protein
AKK42_RS21090	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AKK42_RS21095	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AKK42_RS21105	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AKK42_RS21150	COG0505	Belongs to the CarA family
AKK42_RS21165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AKK42_RS21190	COG1047	Peptidyl-prolyl cis-trans
AKK42_RS21205	COG0196	riboflavin kinase activity
AKK42_RS21215	COG0583	DNA-binding transcription factor activity
AKK42_RS21240	COG4735	regulation of single-species biofilm formation
AKK42_RS21245	COG1584	GPR1 FUN34 yaaH family protein
AKK42_RS21250	COG0477	Major facilitator Superfamily
AKK42_RS21255	COG0521	Mo-molybdopterin cofactor biosynthetic process
AKK42_RS21260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AKK42_RS21265	COG1115	amino acid carrier protein
AKK42_RS21275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AKK42_RS21285	COG0527	aspartate kinase activity
AKK42_RS21285	COG0460	homoserine dehydrogenase
AKK42_RS21295	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AKK42_RS21300	COG0745	RESPONSE REGULATOR receiver
AKK42_RS21305	COG4452	Inner membrane protein CreD
AKK42_RS21310	COG2205	protein histidine kinase activity
AKK42_RS21315	COG0745	RESPONSE REGULATOR receiver
AKK42_RS21320	COG3045	CreA protein
AKK42_RS21325	COG2207	Transcriptional regulator
AKK42_RS21325	COG3708	Transcriptional regulator
AKK42_RS21345	COG0741	lytic transglycosylase activity
AKK42_RS21350	COG0488	(ABC) transporter
AKK42_RS21360	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AKK42_RS21365	COG0560	Phosphoserine phosphatase
AKK42_RS21370	COG3726	membrane protein affecting hemolysin expression
AKK42_RS21400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AKK42_RS21405	COG0084	hydrolase, TatD family'
AKK42_RS21410	COG4667	esterase of the alpha-beta hydrolase superfamily
AKK42_RS21420	COG2823	Periplasmic or secreted lipoprotein
AKK42_RS21430	COG1011	Hydrolase
AKK42_RS21435	COG0456	acetyltransferase
AKK42_RS21440	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AKK42_RS21475	COG3706	GGDEF domain
AKK42_RS21480	COG4114	ferric iron reductase
AKK42_RS21485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AKK42_RS21485	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AKK42_RS21490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AKK42_RS21495	COG2197	response regulator
AKK42_RS21500	COG2197	response regulator
AKK42_RS21505	COG2169	Transcriptional regulator
AKK42_RS21505	COG1917	Cupin 2, conserved barrel domain protein
AKK42_RS21520	COG2966	Psort location CytoplasmicMembrane, score
AKK42_RS21535	COG1484	DNA-dependent DNA replication
AKK42_RS21550	COG5464	transposase or invertase
AKK42_RS21555	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AKK42_RS21560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AKK42_RS21565	COG3716	PTS system mannose fructose sorbose family IID component
AKK42_RS21570	COG3715	PTS system
AKK42_RS21585	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AKK42_RS21585	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AKK42_RS21590	COG1214	PFAM Peptidase M22, glycoprotease
AKK42_RS21590	COG0456	acetyltransferase
AKK42_RS21605	COG0531	amino acid
AKK42_RS21610	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS21615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AKK42_RS21645	COG1846	Transcriptional regulator
AKK42_RS21655	COG0179	Fumarylacetoacetate (FAA) hydrolase
AKK42_RS21665	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS21670	COG3384	dioxygenase
AKK42_RS21680	COG3971	2-oxopent-4-enoate hydratase activity
AKK42_RS21700	COG2368	4-hydroxyphenylacetate
AKK42_RS21705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AKK42_RS21710	COG1966	Carbon starvation protein
AKK42_RS21715	COG2879	small protein
AKK42_RS21720	COG0523	cobalamin synthesis protein
AKK42_RS21735	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS21740	COG5464	transposase or invertase
AKK42_RS21745	COG2207	Transcriptional regulator
AKK42_RS21745	COG1917	Cupin 2, conserved barrel domain protein
AKK42_RS21755	COG2733	membrane
AKK42_RS21770	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
AKK42_RS21775	COG1924	4 iron, 4 sulfur cluster binding
AKK42_RS21790	COG1566	PFAM secretion protein HlyD family protein
AKK42_RS21800	COG5457	Domain of unknown function (DUF1127)
AKK42_RS21805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AKK42_RS21815	COG0583	DNA-binding transcription factor activity
AKK42_RS21855	COG1012	belongs to the aldehyde dehydrogenase family
AKK42_RS21855	COG1454	alcohol dehydrogenase
AKK42_RS21870	COG1882	Formate acetyltransferase
AKK42_RS21875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AKK42_RS21885	COG4869	propanediol catabolic process
AKK42_RS21910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKK42_RS21915	COG0842	Transport permease protein
AKK42_RS21915	COG1129	ABC transporter
AKK42_RS21920	COG0842	Transport permease protein
AKK42_RS21950	COG2850	peptidyl-arginine hydroxylation
AKK42_RS21955	COG5002	protein histidine kinase activity
AKK42_RS21960	COG0745	RESPONSE REGULATOR receiver
AKK42_RS21970	COG1538	Outer membrane efflux protein
AKK42_RS21975	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKK42_RS21980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKK42_RS21985	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AKK42_RS21995	COG3040	lipid binding
AKK42_RS22000	COG0789	Transcriptional regulator
AKK42_RS22010	COG0300	oxidoreductase activity
AKK42_RS22025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AKK42_RS22045	COG3272	Protein of unknown function (DUF1722)
AKK42_RS22050	COG4580	involved in the transport of maltose and maltodextrins
AKK42_RS22065	COG2211	Major facilitator Superfamily
AKK42_RS22070	COG3507	Belongs to the glycosyl hydrolase 43 family
AKK42_RS22095	COG2801	Transposase and inactivated derivatives
AKK42_RS22130	COG0288	reversible hydration of carbon dioxide
AKK42_RS22135	COG0659	secondary active sulfate transmembrane transporter activity
AKK42_RS22140	COG1064	alcohol dehydrogenase
AKK42_RS22145	COG1175	transmembrane transport
AKK42_RS22150	COG0395	ABC-type sugar transport system, permease component
AKK42_RS22155	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AKK42_RS22160	COG3842	ATPase activity
AKK42_RS22175	COG1082	Xylose isomerase domain protein TIM barrel
AKK42_RS22185	COG3962	Belongs to the TPP enzyme family
AKK42_RS22195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AKK42_RS22200	COG1737	Transcriptional regulator
AKK42_RS22200	COG0837	glucose binding
AKK42_RS22205	COG3718	enzyme involved in inositol metabolism
AKK42_RS22220	COG0433	COG0433 Predicted ATPase
AKK42_RS22225	COG0795	lipopolysaccharide-transporting ATPase activity
AKK42_RS22230	COG0795	lipopolysaccharide-transporting ATPase activity
AKK42_RS22240	COG2927	DNA polymerase III (CHI subunit)
AKK42_RS22245	COG0525	valine-tRNA ligase activity
AKK42_RS22270	COG2731	YhcH YjgK YiaL family protein
AKK42_RS22300	COG1263	PTS System
AKK42_RS22300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AKK42_RS22305	COG0366	Alpha amylase catalytic
AKK42_RS22315	COG0602	queuosine metabolic process
AKK42_RS22325	COG3077	Addiction module antitoxin, RelB DinJ family
AKK42_RS22330	COG3711	transcriptional antiterminator
AKK42_RS22330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKK42_RS22335	COG2706	6-phosphogluconolactonase activity
AKK42_RS22350	COG3964	amidohydrolase
AKK42_RS22390	COG0312	modulator of DNA gyrase
AKK42_RS22410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AKK42_RS22420	COG1172	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS22425	COG1172	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS22430	COG1129	ABC transporter
AKK42_RS22440	COG1879	ABC-type sugar transport system periplasmic component
AKK42_RS22455	COG2105	PFAM AIG2 family protein
AKK42_RS22460	COG2911	Protein conserved in bacteria
AKK42_RS22465	COG0729	surface antigen
AKK42_RS22475	COG1253	flavin adenine dinucleotide binding
AKK42_RS22500	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AKK42_RS22515	COG1733	regulation of RNA biosynthetic process
AKK42_RS22520	COG0702	epimerase
AKK42_RS22530	COG0697	spore germination
AKK42_RS22540	COG1113	amino acid transport
AKK42_RS22545	COG0545	Peptidyl-prolyl cis-trans isomerase
AKK42_RS22550	COG3061	Opacity-associated protein A
AKK42_RS22560	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AKK42_RS22565	COG2965	DNA replication, synthesis of RNA primer
AKK42_RS22625	COG1073	alpha beta
AKK42_RS22630	COG3650	response to hydrogen peroxide
AKK42_RS22640	COG1960	acyl-CoA dehydrogenase activity
AKK42_RS22645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKK42_RS22650	COG0557	exoribonuclease II activity
AKK42_RS22665	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AKK42_RS22680	COG0330	HflC and HflK could
AKK42_RS22685	COG0330	HflC and HflK could
AKK42_RS22690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AKK42_RS22710	COG0860	N-Acetylmuramoyl-L-alanine amidase
AKK42_RS22715	COG0802	atpase or kinase
AKK42_RS22720	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AKK42_RS22720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AKK42_RS22725	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AKK42_RS22750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKK42_RS22770	COG1511	domain protein
AKK42_RS22770	COG3264	Mechanosensitive ion channel
AKK42_RS22785	COG1053	succinate dehydrogenase
AKK42_RS22790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AKK42_RS22810	COG2076	Multidrug Resistance protein
AKK42_RS22820	COG5510	response to toxic substance
AKK42_RS22830	COG1509	lysine 2,3-aminomutase activity
AKK42_RS22845	COG3121	Chaperone
AKK42_RS22900	COG0531	amino acid
AKK42_RS22905	COG3030	protein affecting phage T7 exclusion by the F plasmid
AKK42_RS22915	COG1027	Aspartate ammonia-lyase
AKK42_RS22920	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AKK42_RS22935	COG1309	transcriptional regulator
AKK42_RS22965	COG0457	Tetratricopeptide repeat
AKK42_RS22970	COG0726	polysaccharide deacetylase
AKK42_RS22970	COG1649	PFAM Uncharacterised BCR, COG1649
AKK42_RS22975	COG1215	transferase activity, transferring glycosyl groups
AKK42_RS22995	COG0861	Integral membrane protein TerC family
AKK42_RS23030	COG1486	melibiose metabolic process
AKK42_RS23035	COG2169	Transcriptional regulator
AKK42_RS23045	COG2824	Alkylphosphonate utilization operon protein PhnA
AKK42_RS23050	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AKK42_RS23055	COG2188	Transcriptional regulator
AKK42_RS23060	COG3624	Phosphonate C-P lyase system protein PhnG
AKK42_RS23065	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AKK42_RS23070	COG3626	phosphonate metabolism
AKK42_RS23075	COG3627	carbon phosphorus lyase activity
AKK42_RS23080	COG4107	phosphonate C-P lyase system protein PhnK
AKK42_RS23085	COG4778	phosphonate C-P lyase system protein PhnL
AKK42_RS23090	COG3454	Phosphonate metabolism
AKK42_RS23100	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AKK42_RS23110	COG0784	Response regulator, receiver
AKK42_RS23110	COG4191	Histidine kinase
AKK42_RS23115	COG1129	ABC transporter
AKK42_RS23120	COG1172	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS23145	COG3383	formate dehydrogenase (NAD+) activity
AKK42_RS23150	COG3383	formate dehydrogenase (NAD+) activity
AKK42_RS23155	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AKK42_RS23160	COG1301	dicarboxylic acid transport
AKK42_RS23175	COG3162	membrane
AKK42_RS23205	COG3539	Fimbrial protein
AKK42_RS23215	COG1346	cytolysis
AKK42_RS23220	COG1380	Effector of murein hydrolase LrgA
AKK42_RS23225	COG0583	DNA-binding transcription factor activity
AKK42_RS23230	COG0025	NhaP-type Na H and K H
AKK42_RS23235	COG2252	PERMEase
AKK42_RS23240	COG0625	glutathione transferase activity
AKK42_RS23245	COG0789	Transcriptional regulator
AKK42_RS23255	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AKK42_RS23280	COG3842	ATPase activity
AKK42_RS23285	COG1234	tRNA 3'-trailer cleavage
AKK42_RS23290	COG1609	Transcriptional regulator
AKK42_RS23295	COG0483	inositol monophosphate 1-phosphatase activity
AKK42_RS23305	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AKK42_RS23330	COG4771	TonB-dependent receptor
AKK42_RS23355	COG2315	Protein conserved in bacteria
AKK42_RS23360	COG0432	Pfam Uncharacterised protein family UPF0047
AKK42_RS23375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AKK42_RS23380	COG0305	Participates in initiation and elongation during chromosome replication
AKK42_RS23395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AKK42_RS23410	COG0735	belongs to the Fur family
AKK42_RS23415	COG3237	CsbD-like
AKK42_RS23425	COG0534	Mate efflux family protein
AKK42_RS23435	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AKK42_RS23505	COG0251	oxidation-reduction process
AKK42_RS23515	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AKK42_RS23525	COG0527	aspartate kinase activity
AKK42_RS23585	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AKK42_RS23595	COG0456	acetyltransferase
AKK42_RS23625	COG0151	Belongs to the GarS family
AKK42_RS23635	COG4191	Histidine kinase
AKK42_RS23645	COG3678	ATP-independent chaperone mediated protein folding
AKK42_RS23680	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AKK42_RS23695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AKK42_RS23700	COG2104	thiamine diphosphate biosynthetic process
AKK42_RS23710	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AKK42_RS23720	COG3706	GGDEF domain
AKK42_RS23730	COG1447	Phosphotransferase system cellobiose-specific component IIA
AKK42_RS23735	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AKK42_RS23770	COG0250	Participates in transcription elongation, termination and antitermination
AKK42_RS23815	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AKK42_RS23840	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AKK42_RS23850	COG1739	Uncharacterized protein family UPF0029
AKK42_RS23895	COG0805	protein transport
AKK42_RS23915	COG3165	ubiquinone biosynthetic process from chorismate
AKK42_RS23935	COG0412	Dienelactone hydrolase
AKK42_RS23945	COG0583	DNA-binding transcription factor activity
AKK42_RS23950	COG0697	spore germination
AKK42_RS23955	COG0561	phosphatase activity
AKK42_RS23960	COG2267	carboxylic ester hydrolase activity
AKK42_RS23965	COG1280	lysine exporter protein (LysE YggA)
AKK42_RS23975	COG1280	lysine exporter protein (LysE YggA)
AKK42_RS24010	COG0210	DNA helicase
AKK42_RS24015	COG1011	Hydrolase
AKK42_RS24045	COG3072	Adenylate cyclase
AKK42_RS24065	COG2959	enzyme of heme biosynthesis
AKK42_RS24070	COG3071	HemY protein
AKK42_RS24120	COG2244	polysaccharide biosynthetic process
AKK42_RS24125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AKK42_RS24130	COG0456	acetyltransferase
AKK42_RS24135	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AKK42_RS24140	COG1088	dTDP-glucose 4,6-dehydratase activity
AKK42_RS24145	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AKK42_RS24150	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AKK42_RS24160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AKK42_RS24165	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AKK42_RS24175	COG3118	belongs to the thioredoxin family
AKK42_RS24195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AKK42_RS24200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AKK42_RS24210	COG0583	DNA-binding transcription factor activity
AKK42_RS24215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AKK42_RS24230	COG3978	acetolactate synthase activity
AKK42_RS24250	COG3085	chromosome segregation
AKK42_RS24320	COG0583	DNA-binding transcription factor activity
AKK42_RS24335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AKK42_RS24350	COG3443	Belongs to the bacterial solute-binding protein 9 family
AKK42_RS24355	COG2207	Transcriptional regulator
AKK42_RS24365	COG0371	Dehydrogenase
AKK42_RS24375	COG2190	(PTS) system
AKK42_RS24375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AKK42_RS24375	COG1263	PTS System
AKK42_RS24380	COG1609	Transcriptional regulator
AKK42_RS24385	COG0583	DNA-binding transcription factor activity
AKK42_RS24390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AKK42_RS24395	COG0527	aspartate kinase activity
AKK42_RS24395	COG0460	homoserine dehydrogenase
AKK42_RS24400	COG0626	cystathionine gamma-synthase activity
AKK42_RS24415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AKK42_RS24425	COG1609	Transcriptional regulator
AKK42_RS24430	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AKK42_RS24445	COG1575	Belongs to the MenA family. Type 1 subfamily
AKK42_RS24465	COG3678	ATP-independent chaperone mediated protein folding
AKK42_RS24470	COG0745	RESPONSE REGULATOR receiver
AKK42_RS24475	COG2205	protein histidine kinase activity
AKK42_RS24480	COG2258	MOSC domain
AKK42_RS24485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AKK42_RS24525	COG1129	ABC transporter
AKK42_RS24530	COG1172	Belongs to the binding-protein-dependent transport system permease family
AKK42_RS24540	COG1454	alcohol dehydrogenase
AKK42_RS24550	COG0110	maltose O-acetyltransferase activity
AKK42_RS24555	COG2211	Major facilitator Superfamily
AKK42_RS24615	COG0205	6-phosphofructokinase activity
AKK42_RS24630	COG0243	molybdopterin cofactor binding
AKK42_RS24630	COG3383	formate dehydrogenase (NAD+) activity
AKK42_RS24635	COG3383	formate dehydrogenase (NAD+) activity
AKK42_RS24635	COG0243	molybdopterin cofactor binding
AKK42_RS24640	COG0437	4 iron, 4 sulfur cluster binding
AKK42_RS24645	COG2864	formate dehydrogenase
AKK42_RS24660	COG0456	acetyltransferase
AKK42_RS24675	COG1011	Hydrolase
AKK42_RS24680	COG2271	Major facilitator Superfamily
AKK42_RS24685	COG1082	Xylose isomerase domain protein TIM barrel
AKK42_RS24690	COG2188	Transcriptional regulator
AKK42_RS24710	COG3852	Histidine kinase
AKK42_RS24735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AKK42_RS24735	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AKK42_RS24740	COG0204	Acyl-transferase
AKK42_RS24750	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AKK42_RS24755	COG3084	Protein conserved in bacteria
AKK42_RS24765	COG1763	Mo-molybdopterin cofactor biosynthetic process